locus-tag	class	description
BLEG1_RS00020	COG3880	PFAM UvrB UvrC protein
BLEG1_RS00025	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BLEG1_RS00030	COG0542	response to heat
BLEG1_RS00035	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BLEG1_RS00040	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BLEG1_RS00045	COG4956	integral membrane protein (PIN domain superfamily)
BLEG1_RS00050	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BLEG1_RS00055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BLEG1_RS00060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLEG1_RS00065	COG1045	serine acetyltransferase
BLEG1_RS00070	COG0215	cysteine-tRNA ligase activity
BLEG1_RS00080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLEG1_RS00085	COG3688	RNA-binding protein containing a PIN domain
BLEG1_RS00095	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLEG1_RS00100	COG0250	Participates in transcription elongation, termination and antitermination
BLEG1_RS00105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLEG1_RS00110	COG0081	regulation of translation
BLEG1_RS00115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLEG1_RS00120	COG0222	ribosome binding
BLEG1_RS00125	COG2813	Specifically methylates the guanine in position
BLEG1_RS00130	COG0085	RNA polymerase activity
BLEG1_RS00135	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLEG1_RS00140	COG1358	cellular component organization or biogenesis
BLEG1_RS00145	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLEG1_RS00150	COG0049	tRNA binding
BLEG1_RS00155	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLEG1_RS00160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLEG1_RS00170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BLEG1_RS00175	COG0088	Forms part of the polypeptide exit tunnel
BLEG1_RS00180	COG0089	rRNA binding
BLEG1_RS00185	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BLEG1_RS00190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLEG1_RS00195	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLEG1_RS00200	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLEG1_RS00205	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLEG1_RS00210	COG0255	Belongs to the universal ribosomal protein uL29 family
BLEG1_RS00215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLEG1_RS00220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLEG1_RS00225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLEG1_RS00230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BLEG1_RS00235	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLEG1_RS00240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLEG1_RS00245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLEG1_RS00250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BLEG1_RS00255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLEG1_RS00260	COG1841	ribosomal large subunit assembly
BLEG1_RS00265	COG0200	Binds to the 23S rRNA
BLEG1_RS00270	COG0201	protein transport
BLEG1_RS00275	COG0563	adenylate kinase activity
BLEG1_RS00280	COG0024	Methionine aminopeptidase
BLEG1_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLEG1_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLEG1_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLEG1_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLEG1_RS00305	COG0202	RNA polymerase activity
BLEG1_RS00310	COG0203	ribosomal protein L17
BLEG1_RS00315	COG1122	ATPase activity
BLEG1_RS00325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLEG1_RS00330	COG0101	tRNA pseudouridine synthase activity
BLEG1_RS00335	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLEG1_RS00340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLEG1_RS00365	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS00370	COG3711	transcriptional antiterminator
BLEG1_RS00380	COG0489	protein tyrosine kinase activity
BLEG1_RS00390	COG2194	sulfuric ester hydrolase activity
BLEG1_RS00395	COG0726	polysaccharide deacetylase
BLEG1_RS00435	COG0577	efflux transmembrane transporter activity
BLEG1_RS00435	COG1136	(ABC) transporter
BLEG1_RS00445	COG0784	Response regulator, receiver
BLEG1_RS00445	COG2198	Histidine kinase
BLEG1_RS00445	COG5002	protein histidine kinase activity
BLEG1_RS00460	COG0791	NLP P60 protein
BLEG1_RS00460	COG0741	lytic transglycosylase activity
BLEG1_RS00495	COG0604	alcohol dehydrogenase
BLEG1_RS00555	COG0789	Transcriptional regulator
BLEG1_RS00565	COG0789	Transcriptional regulator
BLEG1_RS00585	COG0488	(ABC) transporter
BLEG1_RS00605	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
BLEG1_RS00665	COG0726	polysaccharide deacetylase
BLEG1_RS00705	COG1595	DNA-templated transcription, initiation
BLEG1_RS00710	COG5662	AntiSigma factor
BLEG1_RS00715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLEG1_RS00720	COG4856	YbbR-like protein
BLEG1_RS00725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLEG1_RS00730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLEG1_RS00745	COG1316	TRANSCRIPTIONal
BLEG1_RS00750	COG0456	acetyltransferase
BLEG1_RS00750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLEG1_RS00775	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLEG1_RS00780	COG1349	DNA-binding transcription factor activity
BLEG1_RS00785	COG0110	maltose O-acetyltransferase activity
BLEG1_RS00795	COG3433	isochorismatase activity
BLEG1_RS00795	COG1535	isochorismatase
BLEG1_RS00800	COG1078	dGTPase activity
BLEG1_RS00805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLEG1_RS00815	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS00820	COG0789	Transcriptional regulator
BLEG1_RS00830	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLEG1_RS00840	COG0180	Tryptophanyl-tRNA synthetase
BLEG1_RS00860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS00865	COG2267	carboxylic ester hydrolase activity
BLEG1_RS00870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLEG1_RS00890	COG0628	permease
BLEG1_RS00895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BLEG1_RS00895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLEG1_RS00910	COG0456	acetyltransferase
BLEG1_RS00915	COG0789	Transcriptional regulator
BLEG1_RS00920	COG1132	(ABC) transporter
BLEG1_RS00935	COG0604	alcohol dehydrogenase
BLEG1_RS00940	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLEG1_RS00945	COG1263	PTS System
BLEG1_RS00945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLEG1_RS00960	COG4841	protein insertion into membrane
BLEG1_RS00990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BLEG1_RS00995	COG1984	allophanate hydrolase subunit 2
BLEG1_RS01000	COG4336	lyase activity
BLEG1_RS01005	COG1914	H( )-stimulated, divalent metal cation uptake system
BLEG1_RS01010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BLEG1_RS01015	COG0840	transmembrane signaling receptor activity
BLEG1_RS01020	COG1842	Phage shock protein A
BLEG1_RS01030	COG0640	Transcriptional regulator
BLEG1_RS01035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLEG1_RS01040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLEG1_RS01050	COG0477	Major facilitator Superfamily
BLEG1_RS01055	COG0583	DNA-binding transcription factor activity
BLEG1_RS01075	COG2066	Belongs to the glutaminase family
BLEG1_RS01080	COG0697	spore germination
BLEG1_RS01100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLEG1_RS01115	COG4221	oxidoreductase activity
BLEG1_RS01135	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS01145	COG0667	Aldo Keto reductase
BLEG1_RS01155	COG0789	Transcriptional regulator
BLEG1_RS01160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLEG1_RS01185	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS01200	COG1063	alcohol dehydrogenase
BLEG1_RS01205	COG1720	tRNA m6t6A37 methyltransferase activity
BLEG1_RS01210	COG5646	InterPro IPR014922
BLEG1_RS01215	COG1349	DNA-binding transcription factor activity
BLEG1_RS01220	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS01225	COG3718	enzyme involved in inositol metabolism
BLEG1_RS01230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLEG1_RS01235	COG3962	Belongs to the TPP enzyme family
BLEG1_RS01240	COG1082	Xylose isomerase domain protein TIM barrel
BLEG1_RS01245	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS01250	COG0191	fructose-bisphosphate aldolase activity
BLEG1_RS01255	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS01260	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLEG1_RS01270	COG0556	nucleotide-excision repair
BLEG1_RS01275	COG1063	alcohol dehydrogenase
BLEG1_RS01285	COG3829	transcription factor binding
BLEG1_RS01285	COG3290	protein histidine kinase activity
BLEG1_RS01290	COG1454	alcohol dehydrogenase
BLEG1_RS01300	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS01305	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BLEG1_RS01315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLEG1_RS01330	COG0456	acetyltransferase
BLEG1_RS01355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS01375	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLEG1_RS01385	COG3634	alkyl hydroperoxide reductase activity
BLEG1_RS01390	COG0450	alkyl hydroperoxide reductase
BLEG1_RS01395	COG0697	spore germination
BLEG1_RS01405	COG0456	acetyltransferase
BLEG1_RS01410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLEG1_RS01415	COG1917	Cupin 2, conserved barrel domain protein
BLEG1_RS01425	COG0584	glycerophosphoryl diester phosphodiesterase
BLEG1_RS01440	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS01445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLEG1_RS01450	COG1802	Transcriptional regulator
BLEG1_RS01455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BLEG1_RS01465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BLEG1_RS01470	COG1063	alcohol dehydrogenase
BLEG1_RS01475	COG1312	Catalyzes the dehydration of D-mannonate
BLEG1_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS01485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLEG1_RS01490	COG0800	Aldolase
BLEG1_RS01495	COG1064	alcohol dehydrogenase
BLEG1_RS01510	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS01525	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS01530	COG4209	transmembrane transport
BLEG1_RS01535	COG1609	Transcriptional regulator
BLEG1_RS01540	COG1228	amidohydrolase
BLEG1_RS01555	COG0402	S-adenosylhomocysteine deaminase activity
BLEG1_RS01560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BLEG1_RS01565	COG0628	permease
BLEG1_RS01575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLEG1_RS01585	COG3655	Transcriptional regulator
BLEG1_RS01600	COG0604	alcohol dehydrogenase
BLEG1_RS01605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BLEG1_RS01620	COG1309	transcriptional regulator
BLEG1_RS01630	COG0586	Pfam SNARE associated Golgi protein
BLEG1_RS01645	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS01650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLEG1_RS01655	COG2011	ABC-type metal ion transport system permease component
BLEG1_RS01665	COG1473	amidohydrolase
BLEG1_RS01675	COG1609	Transcriptional regulator
BLEG1_RS01680	COG0561	phosphatase activity
BLEG1_RS01685	COG1522	sequence-specific DNA binding
BLEG1_RS01710	COG0531	amino acid
BLEG1_RS01715	COG0697	spore germination
BLEG1_RS01725	COG0477	Major facilitator Superfamily
BLEG1_RS01740	COG2409	Drug exporters of the RND superfamily
BLEG1_RS01745	COG5002	protein histidine kinase activity
BLEG1_RS01750	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS01780	COG2197	response regulator
BLEG1_RS01790	COG2217	Heavy metal translocating P-type atpase
BLEG1_RS01805	COG1823	symporter activity
BLEG1_RS01840	COG0473	3-isopropylmalate dehydrogenase activity
BLEG1_RS01860	COG1609	Transcriptional regulator
BLEG1_RS01865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLEG1_RS01870	COG1869	D-ribose catabolic process
BLEG1_RS01875	COG1129	ABC transporter
BLEG1_RS01880	COG1172	Belongs to the binding-protein-dependent transport system permease family
BLEG1_RS01885	COG1879	ABC-type sugar transport system periplasmic component
BLEG1_RS01905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLEG1_RS01930	COG0346	lactoylglutathione lyase activity
BLEG1_RS01935	COG2112	serine threonine protein kinase
BLEG1_RS01950	COG0697	spore germination
BLEG1_RS01975	COG1335	isochorismatase
BLEG1_RS02005	COG0431	NADPH-dependent FMN reductase
BLEG1_RS02010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLEG1_RS02020	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BLEG1_RS02025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLEG1_RS02030	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS02035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLEG1_RS02040	COG2409	Drug exporters of the RND superfamily
BLEG1_RS02090	COG2188	Transcriptional regulator
BLEG1_RS02095	COG1486	melibiose metabolic process
BLEG1_RS02100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLEG1_RS02105	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLEG1_RS02140	COG0515	serine threonine protein kinase
BLEG1_RS02145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BLEG1_RS02150	COG1132	(ABC) transporter
BLEG1_RS02180	COG1253	flavin adenine dinucleotide binding
BLEG1_RS02185	COG1253	flavin adenine dinucleotide binding
BLEG1_RS02315	COG1694	Mazg nucleotide pyrophosphohydrolase
BLEG1_RS02325	COG2207	Transcriptional regulator
BLEG1_RS02345	COG0165	Argininosuccinate lyase
BLEG1_RS02350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLEG1_RS02385	COG1695	Transcriptional regulator
BLEG1_RS02400	COG1612	heme a metabolic process
BLEG1_RS02415	COG1846	Transcriptional regulator
BLEG1_RS02420	COG0778	Nitroreductase
BLEG1_RS02425	COG3588	fructose-bisphosphate aldolase
BLEG1_RS02430	COG2329	Antibiotic biosynthesis monooxygenase
BLEG1_RS02445	COG0318	PFAM AMP-dependent synthetase and ligase
BLEG1_RS02450	COG0183	Belongs to the thiolase family
BLEG1_RS02460	COG0124	histidyl-tRNA synthetase
BLEG1_RS02465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLEG1_RS02490	COG1309	transcriptional regulator
BLEG1_RS02520	COG3279	Response regulator of the LytR AlgR family
BLEG1_RS02535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLEG1_RS02540	COG1309	transcriptional regulator
BLEG1_RS02555	COG3711	transcriptional antiterminator
BLEG1_RS02560	COG1263	PTS System
BLEG1_RS02560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLEG1_RS02560	COG2190	(PTS) system
BLEG1_RS02565	COG2723	6-phospho-beta-galactosidase activity
BLEG1_RS02585	COG2508	Transcriptional regulator
BLEG1_RS02595	COG4753	response regulator
BLEG1_RS02595	COG2207	Transcriptional regulator
BLEG1_RS02600	COG2972	Histidine kinase
BLEG1_RS02605	COG1653	transport
BLEG1_RS02610	COG1175	transmembrane transport
BLEG1_RS02615	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS02620	COG0445	tRNA wobble uridine modification
BLEG1_RS02635	COG5444	nuclease activity
BLEG1_RS02720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLEG1_RS02735	COG4209	transmembrane transport
BLEG1_RS02740	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS02760	COG1472	Belongs to the glycosyl hydrolase 3 family
BLEG1_RS02765	COG2207	Transcriptional regulator
BLEG1_RS02780	COG3764	Sortase (surface protein transpeptidase)
BLEG1_RS02785	COG1959	2 iron, 2 sulfur cluster binding
BLEG1_RS02790	COG4821	SIS domain
BLEG1_RS02810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS02825	COG1811	Na channel or pump
BLEG1_RS02835	COG3173	Aminoglycoside phosphotransferase
BLEG1_RS02840	COG0402	S-adenosylhomocysteine deaminase activity
BLEG1_RS02855	COG1982	Orn Lys Arg decarboxylase major
BLEG1_RS02865	COG1175	transmembrane transport
BLEG1_RS02870	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS02880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BLEG1_RS02905	COG0601	transmembrane transport
BLEG1_RS02910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS02930	COG2851	Citrate transporter
BLEG1_RS02940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BLEG1_RS02945	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLEG1_RS02950	COG1414	Transcriptional regulator
BLEG1_RS02975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLEG1_RS02985	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLEG1_RS02990	COG0471	metal ion transport
BLEG1_RS02995	COG0436	Aminotransferase
BLEG1_RS03000	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BLEG1_RS03005	COG0235	Class ii aldolase
BLEG1_RS03010	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLEG1_RS03015	COG1850	ribulose-bisphosphate carboxylase activity
BLEG1_RS03025	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BLEG1_RS03090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLEG1_RS03095	COG0402	S-adenosylhomocysteine deaminase activity
BLEG1_RS03115	COG1131	(ABC) transporter
BLEG1_RS03125	COG1063	alcohol dehydrogenase
BLEG1_RS03140	COG4335	DNA alkylation repair
BLEG1_RS03145	COG3239	Fatty acid desaturase
BLEG1_RS03150	COG4585	Histidine kinase
BLEG1_RS03155	COG2197	response regulator
BLEG1_RS03165	COG4208	sulfate ABC transporter
BLEG1_RS03175	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BLEG1_RS03180	COG0667	Aldo Keto reductase
BLEG1_RS03185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLEG1_RS03195	COG1309	transcriptional regulator
BLEG1_RS03200	COG2814	Major facilitator Superfamily
BLEG1_RS03205	COG1126	abc transporter atp-binding protein
BLEG1_RS03210	COG0765	amino acid transport
BLEG1_RS03215	COG4597	amino acid ABC transporter
BLEG1_RS03220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLEG1_RS03240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLEG1_RS03260	COG0154	amidase activity
BLEG1_RS03265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLEG1_RS03270	COG1469	GTP cyclohydrolase I activity
BLEG1_RS03275	COG3443	Belongs to the bacterial solute-binding protein 9 family
BLEG1_RS03280	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLEG1_RS03285	COG1121	(ABC) transporter
BLEG1_RS03290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLEG1_RS03320	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLEG1_RS03325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLEG1_RS03330	COG4297	protein containing double-stranded beta helix domain
BLEG1_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS03370	COG0456	acetyltransferase
BLEG1_RS03395	COG2378	regulation of single-species biofilm formation
BLEG1_RS03420	COG1959	2 iron, 2 sulfur cluster binding
BLEG1_RS03425	COG0492	ferredoxin-NADP+ reductase activity
BLEG1_RS03435	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BLEG1_RS03465	COG1988	membrane-bound metal-dependent
BLEG1_RS03470	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLEG1_RS03475	COG0390	transport system, permease component
BLEG1_RS03485	COG0778	Nitroreductase
BLEG1_RS03505	COG4536	flavin adenine dinucleotide binding
BLEG1_RS03510	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLEG1_RS03515	COG1074	ATP-dependent DNA helicase activity
BLEG1_RS03520	COG2807	transmembrane transport
BLEG1_RS03535	COG1846	Transcriptional regulator
BLEG1_RS03540	COG2153	protein acetylation
BLEG1_RS03545	COG2814	Major facilitator Superfamily
BLEG1_RS03560	COG1388	LysM domain
BLEG1_RS03560	COG3584	3D domain protein
BLEG1_RS03575	COG1175	transmembrane transport
BLEG1_RS03580	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS03585	COG5578	integral membrane protein
BLEG1_RS03600	COG0693	protein deglycase activity
BLEG1_RS03610	COG2971	BadF BadG BcrA BcrD
BLEG1_RS03615	COG1737	Transcriptional regulator
BLEG1_RS03620	COG3876	Protein conserved in bacteria
BLEG1_RS03625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLEG1_RS03635	COG1131	(ABC) transporter
BLEG1_RS03660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BLEG1_RS03665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLEG1_RS03670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BLEG1_RS03670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLEG1_RS03680	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS03690	COG0028	Belongs to the TPP enzyme family
BLEG1_RS03695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BLEG1_RS03700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLEG1_RS03715	COG1175	transmembrane transport
BLEG1_RS03720	COG3833	ABC-type maltose transport systems, permease component
BLEG1_RS03725	COG0366	Alpha amylase catalytic
BLEG1_RS03730	COG1609	Transcriptional regulator
BLEG1_RS03735	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS03740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLEG1_RS03745	COG0569	domain protein
BLEG1_RS03800	COG0175	sulfate reduction
BLEG1_RS03805	COG2046	Belongs to the sulfate adenylyltransferase family
BLEG1_RS03810	COG0529	Catalyzes the synthesis of activated sulfate
BLEG1_RS03815	COG1587	Uroporphyrinogen-III synthase
BLEG1_RS03815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLEG1_RS03825	COG1648	precorrin-2 dehydrogenase activity
BLEG1_RS03825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLEG1_RS03830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLEG1_RS03835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLEG1_RS03845	COG1051	belongs to the nudix hydrolase family
BLEG1_RS03865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLEG1_RS03870	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLEG1_RS03875	COG0733	neurotransmitter:sodium symporter activity
BLEG1_RS03890	COG0658	competence protein
BLEG1_RS03890	COG2333	competence protein COMEC
BLEG1_RS03900	COG3209	COG3209 Rhs family protein
BLEG1_RS04030	COG1914	H( )-stimulated, divalent metal cation uptake system
BLEG1_RS04040	COG2323	membrane
BLEG1_RS04045	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLEG1_RS04060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLEG1_RS04085	COG0583	DNA-binding transcription factor activity
BLEG1_RS04090	COG2855	membrane
BLEG1_RS04115	COG2197	response regulator
BLEG1_RS04120	COG3142	Participates in the control of copper homeostasis
BLEG1_RS04130	COG1682	transport, permease protein
BLEG1_RS04135	COG1134	teichoic acid transport
BLEG1_RS04155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS04165	COG3414	Phosphotransferase system galactitol-specific IIB component
BLEG1_RS04170	COG3775	system Galactitol-specific IIC component
BLEG1_RS04175	COG1063	alcohol dehydrogenase
BLEG1_RS04180	COG1063	alcohol dehydrogenase
BLEG1_RS04185	COG0488	(ABC) transporter
BLEG1_RS04200	COG3448	diguanylate cyclase activity
BLEG1_RS04200	COG4175	Glycine betaine
BLEG1_RS04205	COG2050	protein possibly involved in aromatic compounds catabolism
BLEG1_RS04210	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLEG1_RS04220	COG2197	response regulator
BLEG1_RS04225	COG4585	Histidine kinase
BLEG1_RS04265	COG0583	DNA-binding transcription factor activity
BLEG1_RS04275	COG1053	succinate dehydrogenase
BLEG1_RS04290	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS04290	COG2202	Pas domain
BLEG1_RS04300	COG1418	mRNA catabolic process
BLEG1_RS04310	COG0438	transferase activity, transferring glycosyl groups
BLEG1_RS04310	COG1216	Glycosyl transferase, family 2
BLEG1_RS04320	COG2814	Major facilitator Superfamily
BLEG1_RS04325	COG0500	methyltransferase
BLEG1_RS04340	COG0501	Belongs to the peptidase M48B family
BLEG1_RS04345	COG4989	oxidoreductase activity
BLEG1_RS04360	COG1309	transcriptional regulator
BLEG1_RS04380	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS04385	COG1917	Cupin 2, conserved barrel domain protein
BLEG1_RS04385	COG2207	Transcriptional regulator
BLEG1_RS04400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLEG1_RS04405	COG1482	cell wall glycoprotein biosynthetic process
BLEG1_RS04410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS04450	COG1091	dTDP-4-dehydrorhamnose reductase activity
BLEG1_RS04515	COG1940	carbohydrate kinase activity
BLEG1_RS04520	COG4187	Peptidase family M20/M25/M40
BLEG1_RS04525	COG2814	Major facilitator Superfamily
BLEG1_RS04530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLEG1_RS04540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BLEG1_RS04560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLEG1_RS04570	COG2252	PERMEase
BLEG1_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS04625	COG0737	Belongs to the 5'-nucleotidase family
BLEG1_RS04630	COG1073	alpha beta
BLEG1_RS04635	COG0326	Molecular chaperone. Has ATPase activity
BLEG1_RS04640	COG2124	cytochrome p450
BLEG1_RS04645	COG2031	fatty acid transporter
BLEG1_RS04650	COG1454	alcohol dehydrogenase
BLEG1_RS04655	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS04660	COG1510	regulation of RNA biosynthetic process
BLEG1_RS04670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLEG1_RS04685	COG2153	protein acetylation
BLEG1_RS04695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLEG1_RS04700	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
BLEG1_RS04710	COG2059	Chromate
BLEG1_RS04720	COG0789	Transcriptional regulator
BLEG1_RS04735	COG1695	Transcriptional regulator
BLEG1_RS04740	COG3424	synthase
BLEG1_RS04760	COG1175	transmembrane transport
BLEG1_RS04765	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS04785	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLEG1_RS04790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLEG1_RS04795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLEG1_RS04800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLEG1_RS04805	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLEG1_RS04810	COG0047	phosphoribosylformylglycinamidine synthase activity
BLEG1_RS04815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLEG1_RS04820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLEG1_RS04825	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BLEG1_RS04830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLEG1_RS04835	COG0138	bifunctional purine biosynthesis protein purh
BLEG1_RS04840	COG0151	Belongs to the GarS family
BLEG1_RS04870	COG0384	phenazine biosynthesis protein PhzF
BLEG1_RS04885	COG2197	response regulator
BLEG1_RS04890	COG1131	(ABC) transporter
BLEG1_RS04910	COG1510	regulation of RNA biosynthetic process
BLEG1_RS04940	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLEG1_RS04945	COG4496	protein, YerC YecD
BLEG1_RS04950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLEG1_RS04965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLEG1_RS04975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS04980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS04985	COG1120	ATPase activity
BLEG1_RS04990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLEG1_RS04995	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BLEG1_RS05000	COG0210	DNA helicase
BLEG1_RS05005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLEG1_RS05010	COG4851	CamS sex pheromone cAM373 precursor
BLEG1_RS05020	COG2318	DinB family
BLEG1_RS05025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLEG1_RS05030	COG0154	amidase activity
BLEG1_RS05035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLEG1_RS05040	COG1597	lipid kinase activity
BLEG1_RS05045	COG1349	DNA-binding transcription factor activity
BLEG1_RS05075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLEG1_RS05080	COG0686	Belongs to the AlaDH PNT family
BLEG1_RS05085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLEG1_RS05085	COG2508	Transcriptional regulator
BLEG1_RS05090	COG1115	amino acid carrier protein
BLEG1_RS05095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLEG1_RS05115	COG0024	Methionine aminopeptidase
BLEG1_RS05125	COG1830	Aldolase
BLEG1_RS05130	COG1070	Carbohydrate kinase
BLEG1_RS05140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLEG1_RS05155	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS05180	COG1595	DNA-templated transcription, initiation
BLEG1_RS05185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BLEG1_RS05205	COG0398	Pfam SNARE associated Golgi protein
BLEG1_RS05210	COG0456	acetyltransferase
BLEG1_RS05235	COG1414	Transcriptional regulator
BLEG1_RS05240	COG0710	3-dehydroquinate dehydratase activity
BLEG1_RS05245	COG1733	regulation of RNA biosynthetic process
BLEG1_RS05255	COG0431	NADPH-dependent FMN reductase
BLEG1_RS05260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLEG1_RS05265	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BLEG1_RS05270	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BLEG1_RS05290	COG2814	Major facilitator Superfamily
BLEG1_RS05295	COG1378	Sugar-specific transcriptional regulator TrmB
BLEG1_RS05300	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BLEG1_RS05315	COG1380	Effector of murein hydrolase LrgA
BLEG1_RS05320	COG1346	cytolysis
BLEG1_RS05335	COG1078	dGTPase activity
BLEG1_RS05340	COG3048	D-serine ammonia-lyase activity
BLEG1_RS05345	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLEG1_RS05355	COG0583	DNA-binding transcription factor activity
BLEG1_RS05360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLEG1_RS05370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLEG1_RS05375	COG1595	DNA-templated transcription, initiation
BLEG1_RS05395	COG1131	(ABC) transporter
BLEG1_RS05400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLEG1_RS05405	COG5002	protein histidine kinase activity
BLEG1_RS05415	COG2391	methyltransferase activity
BLEG1_RS05420	COG2113	Glycine betaine
BLEG1_RS05425	COG1597	lipid kinase activity
BLEG1_RS05435	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS05440	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS05445	COG0747	negative chemotaxis
BLEG1_RS05450	COG0601	transmembrane transport
BLEG1_RS05455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS05470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLEG1_RS05475	COG3973	AAA domain
BLEG1_RS05480	COG2755	lipolytic protein G-D-S-L family
BLEG1_RS05485	COG1132	(ABC) transporter
BLEG1_RS05490	COG1132	(ABC) transporter
BLEG1_RS05500	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS05505	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLEG1_RS05510	COG1115	amino acid carrier protein
BLEG1_RS05515	COG2244	polysaccharide biosynthetic process
BLEG1_RS05520	COG0405	Gamma-glutamyltransferase
BLEG1_RS05525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLEG1_RS05525	COG1263	PTS System
BLEG1_RS05530	COG0366	Alpha amylase catalytic
BLEG1_RS05535	COG2188	Transcriptional regulator
BLEG1_RS05540	COG0386	Belongs to the glutathione peroxidase family
BLEG1_RS05545	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BLEG1_RS05550	COG0488	(ABC) transporter
BLEG1_RS05555	COG1349	DNA-binding transcription factor activity
BLEG1_RS05560	COG1105	Belongs to the carbohydrate kinase PfkB family
BLEG1_RS05565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS05565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS05565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS05590	COG1077	Cell shape determining protein MreB Mrl
BLEG1_RS05595	COG3011	Protein conserved in bacteria
BLEG1_RS05610	COG3341	Caulimovirus viroplasmin
BLEG1_RS05610	COG0328	RNA-DNA hybrid ribonuclease activity
BLEG1_RS05615	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS05625	COG0753	catalase activity
BLEG1_RS05640	COG1164	Oligoendopeptidase f
BLEG1_RS05650	COG1294	oxidase, subunit
BLEG1_RS05655	COG1271	oxidase subunit
BLEG1_RS05675	COG0535	radical SAM domain protein
BLEG1_RS05685	COG0406	alpha-ribazole phosphatase activity
BLEG1_RS05690	COG1253	flavin adenine dinucleotide binding
BLEG1_RS05700	COG0726	polysaccharide deacetylase
BLEG1_RS05710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLEG1_RS05750	COG1090	epimerase
BLEG1_RS05755	COG2137	regulation of response to DNA damage stimulus
BLEG1_RS05770	COG1988	membrane-bound metal-dependent
BLEG1_RS05775	COG1194	a g-specific adenine glycosylase
BLEG1_RS05795	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS05805	COG3557	Belongs to the UPF0374 family
BLEG1_RS05810	COG1132	(ABC) transporter
BLEG1_RS05815	COG4129	membrane
BLEG1_RS05820	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLEG1_RS05825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BLEG1_RS05840	COG0735	belongs to the Fur family
BLEG1_RS05945	COG5434	Belongs to the glycosyl hydrolase 28 family
BLEG1_RS06035	COG4894	glucomannan catabolic process
BLEG1_RS06045	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLEG1_RS06070	COG1575	Belongs to the MenA family. Type 1 subfamily
BLEG1_RS06080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLEG1_RS06095	COG3012	SEC-C Motif Domain Protein
BLEG1_RS06095	COG1405	negative regulation of cell septum assembly
BLEG1_RS06100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLEG1_RS06105	COG1966	Carbon starvation protein
BLEG1_RS06115	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS06120	COG1131	(ABC) transporter
BLEG1_RS06130	COG1725	Transcriptional regulator
BLEG1_RS06135	COG1131	(ABC) transporter
BLEG1_RS06150	COG0783	Belongs to the Dps family
BLEG1_RS06165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLEG1_RS06190	COG2329	Antibiotic biosynthesis monooxygenase
BLEG1_RS06195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLEG1_RS06200	COG2766	serine protein kinase
BLEG1_RS06205	COG0681	Belongs to the peptidase S26 family
BLEG1_RS06210	COG2718	Belongs to the UPF0229 family
BLEG1_RS06215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLEG1_RS06220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLEG1_RS06225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS06235	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS06240	COG2188	Transcriptional regulator
BLEG1_RS06245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BLEG1_RS06250	COG0363	glucosamine-6-phosphate deaminase activity
BLEG1_RS06255	COG2311	Membrane
BLEG1_RS06260	COG0778	Nitroreductase
BLEG1_RS06265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLEG1_RS06270	COG3153	acetyltransferase
BLEG1_RS06270	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLEG1_RS06280	COG1489	DNA binding
BLEG1_RS06285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLEG1_RS06290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLEG1_RS06295	COG2719	SpoVR family
BLEG1_RS06300	COG1132	(ABC) transporter
BLEG1_RS06310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLEG1_RS06315	COG0501	Belongs to the peptidase M48B family
BLEG1_RS06320	COG1704	LemA family
BLEG1_RS06325	COG1960	acyl-CoA dehydrogenase activity
BLEG1_RS06330	COG0439	Biotin carboxylase
BLEG1_RS06335	COG0511	ligase activity, forming carbon-carbon bonds
BLEG1_RS06340	COG1024	Enoyl-CoA hydratase
BLEG1_RS06345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLEG1_RS06355	COG3842	ATPase activity
BLEG1_RS06360	COG2508	Transcriptional regulator
BLEG1_RS06370	COG4399	Belongs to the UPF0754 family
BLEG1_RS06375	COG4399	Belongs to the UPF0754 family
BLEG1_RS06380	COG3679	Belongs to the UPF0342 family
BLEG1_RS06385	COG0561	phosphatase activity
BLEG1_RS06400	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS06410	COG3481	metal-dependent phosphohydrolase, HD sub domain
BLEG1_RS06420	COG0494	nUDIX hydrolase
BLEG1_RS06430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLEG1_RS06450	COG1846	Transcriptional regulator
BLEG1_RS06455	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLEG1_RS06460	COG0537	adenosine 5'-monophosphoramidase activity
BLEG1_RS06465	COG1131	(ABC) transporter
BLEG1_RS06470	COG4473	ABC transporter
BLEG1_RS06480	COG0785	Cytochrome C biogenesis protein
BLEG1_RS06485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLEG1_RS06490	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BLEG1_RS06495	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BLEG1_RS06500	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BLEG1_RS06505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLEG1_RS06510	COG4492	Belongs to the UPF0735 family
BLEG1_RS06515	COG0077	Prephenate dehydratase
BLEG1_RS06520	COG1827	regulation of RNA biosynthetic process
BLEG1_RS06525	COG1104	cysteine desulfurase activity
BLEG1_RS06530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLEG1_RS06535	COG0157	Belongs to the NadC ModD family
BLEG1_RS06540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLEG1_RS06545	COG1388	LysM domain
BLEG1_RS06565	COG0632	four-way junction helicase activity
BLEG1_RS06570	COG2255	four-way junction helicase activity
BLEG1_RS06580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLEG1_RS06585	COG0343	queuine tRNA-ribosyltransferase activity
BLEG1_RS06590	COG1862	Preprotein translocase
BLEG1_RS06610	COG2244	polysaccharide biosynthetic process
BLEG1_RS06625	COG5416	Lipopolysaccharide assembly protein A domain
BLEG1_RS06630	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BLEG1_RS06630	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BLEG1_RS06635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLEG1_RS06640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLEG1_RS06645	COG1490	D-aminoacyl-tRNA deacylase activity
BLEG1_RS06650	COG1609	Transcriptional regulator
BLEG1_RS06660	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS06665	COG0124	histidyl-tRNA synthetase
BLEG1_RS06670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLEG1_RS06675	COG0460	homoserine dehydrogenase
BLEG1_RS06685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BLEG1_RS06695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BLEG1_RS06700	COG1959	2 iron, 2 sulfur cluster binding
BLEG1_RS06705	COG1104	cysteine desulfurase activity
BLEG1_RS06710	COG0482	sulfurtransferase activity
BLEG1_RS06720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLEG1_RS06725	COG3881	PFAM PRC-barrel domain
BLEG1_RS06740	COG0628	permease
BLEG1_RS06745	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLEG1_RS06750	COG4472	Bacterial protein of unknown function (DUF965)
BLEG1_RS06755	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLEG1_RS06760	COG3906	Belongs to the UPF0473 family
BLEG1_RS06765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLEG1_RS06770	COG4122	O-methyltransferase activity
BLEG1_RS06775	COG0572	uridine kinase
BLEG1_RS06780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLEG1_RS06790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLEG1_RS06805	COG0095	Lipoate-protein ligase
BLEG1_RS06825	COG1587	Uroporphyrinogen-III synthase
BLEG1_RS06830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS06850	COG0776	regulation of translation
BLEG1_RS06855	COG1183	phosphatidylcholine synthase activity
BLEG1_RS06860	COG0688	phosphatidylethanolamine metabolic process
BLEG1_RS06865	COG1320	monovalent cation:proton antiporter activity
BLEG1_RS06870	COG2212	antiporter activity
BLEG1_RS06875	COG1863	multisubunit Na H antiporter MnhE subunit
BLEG1_RS06880	COG0651	ATP synthesis coupled electron transport
BLEG1_RS06885	COG1006	Multisubunit Na H antiporter MnhC subunit
BLEG1_RS06890	COG2111	Na H antiporter
BLEG1_RS06895	COG2111	Na H antiporter
BLEG1_RS06895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLEG1_RS06900	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BLEG1_RS06905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLEG1_RS06910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLEG1_RS06915	COG1534	Rna-binding protein
BLEG1_RS06920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLEG1_RS06925	COG1713	HD superfamily hydrolase involved in NAD metabolism
BLEG1_RS06930	COG0799	negative regulation of ribosome biogenesis
BLEG1_RS06935	COG2996	Protein conserved in bacteria
BLEG1_RS06940	COG2226	methyltransferase
BLEG1_RS06945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLEG1_RS06950	COG1596	polysaccharide export
BLEG1_RS06950	COG1555	photosystem II stabilization
BLEG1_RS06955	COG2131	deaminase
BLEG1_RS06960	COG2333	competence protein COMEC
BLEG1_RS06960	COG0658	competence protein
BLEG1_RS06970	COG1466	dna polymerase III delta subunit
BLEG1_RS06975	COG0268	Binds directly to 16S ribosomal RNA
BLEG1_RS06980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BLEG1_RS06990	COG0481	GTPase activity
BLEG1_RS06995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLEG1_RS07000	COG1420	regulation of RNA biosynthetic process
BLEG1_RS07005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLEG1_RS07010	COG0443	Heat shock 70 kDa protein
BLEG1_RS07015	COG0484	heat shock protein binding
BLEG1_RS07020	COG2264	protein methyltransferase activity
BLEG1_RS07025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLEG1_RS07030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLEG1_RS07035	COG2226	methyltransferase
BLEG1_RS07040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLEG1_RS07045	COG0667	Aldo Keto reductase
BLEG1_RS07055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLEG1_RS07060	COG1610	YqeY-like protein
BLEG1_RS07065	COG1030	water channel activity
BLEG1_RS07070	COG4864	UPF0365 protein
BLEG1_RS07090	COG1702	phosphate starvation-inducible protein PhoH
BLEG1_RS07095	COG1480	7TM receptor with intracellular HD hydrolase
BLEG1_RS07100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLEG1_RS07105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BLEG1_RS07110	COG0295	cytidine deaminase activity
BLEG1_RS07115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLEG1_RS07120	COG1381	Involved in DNA repair and RecF pathway recombination
BLEG1_RS07125	COG0752	glycyl-tRNA synthetase alpha subunit
BLEG1_RS07130	COG0751	glycine-tRNA ligase activity
BLEG1_RS07135	COG0517	IMP dehydrogenase activity
BLEG1_RS07140	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BLEG1_RS07145	COG1671	Belongs to the UPF0178 family
BLEG1_RS07150	COG0358	DNA primase activity
BLEG1_RS07155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLEG1_RS07165	COG2384	SAM-dependent methyltransferase
BLEG1_RS07170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLEG1_RS07175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLEG1_RS07180	COG1329	Transcriptional regulator
BLEG1_RS07190	COG0513	Belongs to the DEAD box helicase family
BLEG1_RS07195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BLEG1_RS07205	COG4191	Histidine kinase
BLEG1_RS07215	COG1121	(ABC) transporter
BLEG1_RS07220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLEG1_RS07225	COG0735	belongs to the Fur family
BLEG1_RS07235	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BLEG1_RS07245	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BLEG1_RS07255	COG4086	secreted protein
BLEG1_RS07265	COG0704	Plays a role in the regulation of phosphate uptake
BLEG1_RS07295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLEG1_RS07300	COG0477	Major facilitator Superfamily
BLEG1_RS07305	COG0768	penicillin binding
BLEG1_RS07325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLEG1_RS07330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLEG1_RS07340	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLEG1_RS07350	COG0705	Rhomboid family
BLEG1_RS07350	COG0457	Tetratricopeptide repeat
BLEG1_RS07355	COG0697	spore germination
BLEG1_RS07375	COG1940	carbohydrate kinase activity
BLEG1_RS07380	COG1027	Aspartate ammonia-lyase
BLEG1_RS07390	COG0352	thiamine-phosphate diphosphorylase activity
BLEG1_RS07400	COG2022	thiamine diphosphate biosynthetic process
BLEG1_RS07405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLEG1_RS07410	COG0351	phosphomethylpyrimidine kinase
BLEG1_RS07425	COG0011	TIGRFAM Protein of
BLEG1_RS07430	COG2153	protein acetylation
BLEG1_RS07435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLEG1_RS07440	COG2382	esterase
BLEG1_RS07450	COG1396	sequence-specific DNA binding
BLEG1_RS07455	COG0114	fumarate hydratase activity
BLEG1_RS07460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLEG1_RS07470	COG4191	Histidine kinase
BLEG1_RS07475	COG1280	lysine exporter protein (LysE YggA)
BLEG1_RS07480	COG3403	YqcI/YcgG family
BLEG1_RS07485	COG4129	membrane
BLEG1_RS07490	COG1376	ErfK ybiS ycfS ynhG family protein
BLEG1_RS07500	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLEG1_RS07520	COG0517	IMP dehydrogenase activity
BLEG1_RS07530	COG2861	carbohydrate metabolic process
BLEG1_RS07535	COG0789	Transcriptional regulator
BLEG1_RS07545	COG0527	aspartate kinase activity
BLEG1_RS07555	COG0300	oxidoreductase activity
BLEG1_RS07560	COG0367	asparagine synthase
BLEG1_RS07565	COG0398	Pfam SNARE associated Golgi protein
BLEG1_RS07585	COG1562	ergosterol biosynthetic process
BLEG1_RS07590	COG2171	N-acyltransferase activity
BLEG1_RS07615	COG2190	(PTS) system
BLEG1_RS07620	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BLEG1_RS07625	COG1850	ribulose-bisphosphate carboxylase activity
BLEG1_RS07630	COG1968	undecaprenyl-diphosphatase activity
BLEG1_RS07635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLEG1_RS07640	COG0494	nUDIX hydrolase
BLEG1_RS07645	COG1300	Membrane
BLEG1_RS07650	COG0735	belongs to the Fur family
BLEG1_RS07665	COG2186	Transcriptional regulator
BLEG1_RS07670	COG0277	FAD linked oxidase domain protein
BLEG1_RS07675	COG0247	lactate metabolic process
BLEG1_RS07680	COG0579	oxidoreductase
BLEG1_RS07685	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLEG1_RS07685	COG0824	Thioesterase
BLEG1_RS07695	COG3246	L-lysine catabolic process to acetate
BLEG1_RS07700	COG1510	regulation of RNA biosynthetic process
BLEG1_RS07705	COG0517	IMP dehydrogenase activity
BLEG1_RS07705	COG1125	glycine betaine transport
BLEG1_RS07710	COG1174	glycine betaine transport
BLEG1_RS07715	COG1732	Glycine betaine
BLEG1_RS07740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLEG1_RS07750	COG1082	Xylose isomerase domain protein TIM barrel
BLEG1_RS07760	COG4974	Belongs to the 'phage' integrase family
BLEG1_RS07765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLEG1_RS07775	COG3871	stress protein (general stress protein 26)
BLEG1_RS07780	COG1764	response to oxidative stress
BLEG1_RS07790	COG2814	Major facilitator Superfamily
BLEG1_RS07800	COG1686	Belongs to the peptidase S11 family
BLEG1_RS07810	COG2172	sigma factor antagonist activity
BLEG1_RS07825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLEG1_RS07840	COG0697	spore germination
BLEG1_RS07845	COG0019	diaminopimelate decarboxylase activity
BLEG1_RS07850	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLEG1_RS07855	COG0583	DNA-binding transcription factor activity
BLEG1_RS07865	COG2079	MmgE PrpD family protein
BLEG1_RS07870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BLEG1_RS07880	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS07885	COG0488	(ABC) transporter
BLEG1_RS07890	COG0656	L-ascorbic acid biosynthetic process
BLEG1_RS07895	COG2133	pyrroloquinoline quinone binding
BLEG1_RS07915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLEG1_RS07920	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLEG1_RS07925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLEG1_RS07930	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS07930	COG2202	Pas domain
BLEG1_RS07940	COG4876	unkown
BLEG1_RS07945	COG1960	acyl-CoA dehydrogenase activity
BLEG1_RS07970	COG1175	transmembrane transport
BLEG1_RS07975	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS07980	COG5578	integral membrane protein
BLEG1_RS07985	COG3534	alpha-L-arabinofuranosidase
BLEG1_RS08000	COG0371	Dehydrogenase
BLEG1_RS08010	COG1069	ribulokinase activity
BLEG1_RS08015	COG2160	L-arabinose isomerase activity
BLEG1_RS08020	COG4213	ABC transporter substrate-binding protein
BLEG1_RS08030	COG4214	carbohydrate transport
BLEG1_RS08035	COG1486	melibiose metabolic process
BLEG1_RS08040	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS08060	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BLEG1_RS08070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLEG1_RS08075	COG2226	methyltransferase
BLEG1_RS08085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLEG1_RS08090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLEG1_RS08095	COG1011	Hydrolase
BLEG1_RS08100	COG4721	ABC-type cobalt transport system, permease component
BLEG1_RS08105	COG1122	ATPase activity
BLEG1_RS08115	COG2094	Belongs to the DNA glycosylase MPG family
BLEG1_RS08130	COG3844	kynureninase activity
BLEG1_RS08140	COG0542	response to heat
BLEG1_RS08150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLEG1_RS08160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLEG1_RS08165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLEG1_RS08170	COG0626	cystathionine gamma-synthase activity
BLEG1_RS08175	COG0708	Exodeoxyribonuclease III
BLEG1_RS08185	COG0217	transcriptional regulatory protein
BLEG1_RS08210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLEG1_RS08215	COG2151	metal-sulfur cluster biosynthetic enzyme
BLEG1_RS08220	COG0702	epimerase
BLEG1_RS08225	COG1757	Na H antiporter
BLEG1_RS08230	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BLEG1_RS08240	COG1175	transmembrane transport
BLEG1_RS08245	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS08250	COG1472	Belongs to the glycosyl hydrolase 3 family
BLEG1_RS08260	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BLEG1_RS08265	COG1473	amidohydrolase
BLEG1_RS08270	COG1473	amidohydrolase
BLEG1_RS08285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLEG1_RS08295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BLEG1_RS08300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLEG1_RS08305	COG2508	Transcriptional regulator
BLEG1_RS08310	COG1288	antiporter activity
BLEG1_RS08315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLEG1_RS08320	COG2202	Pas domain
BLEG1_RS08320	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS08340	COG0800	Aldolase
BLEG1_RS08345	COG4948	Mandelate Racemase Muconate Lactonizing
BLEG1_RS08350	COG2610	gluconate transmembrane transporter activity
BLEG1_RS08375	COG1033	growth of symbiont in host cell
BLEG1_RS08375	COG2409	Drug exporters of the RND superfamily
BLEG1_RS08385	COG1733	regulation of RNA biosynthetic process
BLEG1_RS08395	COG0747	negative chemotaxis
BLEG1_RS08400	COG0601	transmembrane transport
BLEG1_RS08410	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS08415	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS08435	COG3850	Histidine kinase
BLEG1_RS08435	COG5002	protein histidine kinase activity
BLEG1_RS08440	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS08500	COG2378	regulation of single-species biofilm formation
BLEG1_RS08510	COG1131	(ABC) transporter
BLEG1_RS08515	COG2205	protein histidine kinase activity
BLEG1_RS08520	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS08525	COG3420	alginic acid biosynthetic process
BLEG1_RS08535	COG2205	protein histidine kinase activity
BLEG1_RS08540	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS08545	COG1136	(ABC) transporter
BLEG1_RS08550	COG0577	efflux transmembrane transporter activity
BLEG1_RS08565	COG0463	Glycosyl transferase, family 2
BLEG1_RS08570	COG2274	protein secretion by the type I secretion system
BLEG1_RS08580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BLEG1_RS08620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLEG1_RS08625	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BLEG1_RS08630	COG3842	ATPase activity
BLEG1_RS08635	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLEG1_RS08640	COG1609	Transcriptional regulator
BLEG1_RS08665	COG1904	glucuronate isomerase
BLEG1_RS08670	COG3275	phosphorelay sensor kinase activity
BLEG1_RS08675	COG4753	response regulator
BLEG1_RS08675	COG2207	Transcriptional regulator
BLEG1_RS08680	COG2130	NADP-dependent
BLEG1_RS08685	COG2814	Major facilitator Superfamily
BLEG1_RS08695	COG0488	(ABC) transporter
BLEG1_RS08705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLEG1_RS08710	COG0384	phenazine biosynthesis protein PhzF
BLEG1_RS08720	COG1609	Transcriptional regulator
BLEG1_RS08725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLEG1_RS08730	COG0471	metal ion transport
BLEG1_RS08740	COG1119	ATPase activity
BLEG1_RS08760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS08765	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS08770	COG1120	ATPase activity
BLEG1_RS08780	COG0733	neurotransmitter:sodium symporter activity
BLEG1_RS08785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLEG1_RS08790	COG1131	(ABC) transporter
BLEG1_RS08795	COG3835	regulator
BLEG1_RS08800	COG1253	flavin adenine dinucleotide binding
BLEG1_RS08805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLEG1_RS08810	COG3842	ATPase activity
BLEG1_RS08815	COG1177	transmembrane transport
BLEG1_RS08820	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLEG1_RS08840	COG3964	amidohydrolase
BLEG1_RS08860	COG2188	Transcriptional regulator
BLEG1_RS08865	COG1115	amino acid carrier protein
BLEG1_RS08870	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BLEG1_RS08875	COG0402	S-adenosylhomocysteine deaminase activity
BLEG1_RS08925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLEG1_RS08945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BLEG1_RS08945	COG0167	dihydroorotate dehydrogenase activity
BLEG1_RS08950	COG0493	'glutamate synthase
BLEG1_RS08965	COG0457	Tetratricopeptide repeat
BLEG1_RS08975	COG1280	lysine exporter protein (LysE YggA)
BLEG1_RS08985	COG3340	Belongs to the peptidase S51 family
BLEG1_RS09000	COG1621	beta-fructofuranosidase activity
BLEG1_RS09010	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS09015	COG4209	transmembrane transport
BLEG1_RS09020	COG1609	Transcriptional regulator
BLEG1_RS09030	COG2226	methyltransferase
BLEG1_RS09040	COG2610	gluconate transmembrane transporter activity
BLEG1_RS09045	COG3829	transcription factor binding
BLEG1_RS09045	COG3290	protein histidine kinase activity
BLEG1_RS09050	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS09070	COG3414	Phosphotransferase system galactitol-specific IIB component
BLEG1_RS09095	COG1609	Transcriptional regulator
BLEG1_RS09105	COG0667	Aldo Keto reductase
BLEG1_RS09120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BLEG1_RS09120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLEG1_RS09130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BLEG1_RS09135	COG0277	FAD linked oxidase domain protein
BLEG1_RS09150	COG0318	PFAM AMP-dependent synthetase and ligase
BLEG1_RS09165	COG1414	Transcriptional regulator
BLEG1_RS09185	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS09195	COG0662	Cupin 2, conserved barrel domain protein
BLEG1_RS09220	COG0747	negative chemotaxis
BLEG1_RS09225	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS09235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS09240	COG0601	transmembrane transport
BLEG1_RS09245	COG1309	transcriptional regulator
BLEG1_RS09250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLEG1_RS09255	COG1794	racemase activity, acting on amino acids and derivatives
BLEG1_RS09270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLEG1_RS09270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLEG1_RS09280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS09285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLEG1_RS09290	COG1360	Flagellar Motor Protein
BLEG1_RS09295	COG0628	permease
BLEG1_RS09300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLEG1_RS09305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLEG1_RS09310	COG0187	DNA topoisomerase II activity
BLEG1_RS09315	COG1832	CoA-binding protein
BLEG1_RS09320	COG1174	glycine betaine transport
BLEG1_RS09325	COG1125	glycine betaine transport
BLEG1_RS09325	COG0517	IMP dehydrogenase activity
BLEG1_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS09345	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BLEG1_RS09350	COG4841	protein insertion into membrane
BLEG1_RS09360	COG1070	Carbohydrate kinase
BLEG1_RS09370	COG0116	Belongs to the methyltransferase superfamily
BLEG1_RS09380	COG0328	RNA-DNA hybrid ribonuclease activity
BLEG1_RS09385	COG3599	regulation of cell shape
BLEG1_RS09390	COG4474	Belongs to the UPF0398 family
BLEG1_RS09400	COG3359	exonuclease
BLEG1_RS09405	COG1205	dead DEAH box helicase
BLEG1_RS09405	COG1111	helicase
BLEG1_RS09420	COG0400	carboxylic ester hydrolase activity
BLEG1_RS09430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLEG1_RS09455	COG0493	'glutamate synthase
BLEG1_RS09460	COG0070	glutamate synthase
BLEG1_RS09460	COG0069	glutamate synthase activity
BLEG1_RS09460	COG0067	glutamate synthase
BLEG1_RS09480	COG3428	Bacterial PH domain
BLEG1_RS09485	COG3402	PFAM membrane-flanked domain
BLEG1_RS09495	COG1413	lyase activity
BLEG1_RS09520	COG1234	tRNA 3'-trailer cleavage
BLEG1_RS09530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLEG1_RS09545	COG0789	Transcriptional regulator
BLEG1_RS09555	COG3331	DNA recombination
BLEG1_RS09560	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLEG1_RS09560	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLEG1_RS09565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLEG1_RS09575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLEG1_RS09580	COG3935	DnaD domain protein
BLEG1_RS09585	COG0017	Asparaginyl-tRNA synthetase
BLEG1_RS09605	COG0402	S-adenosylhomocysteine deaminase activity
BLEG1_RS09610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLEG1_RS09610	COG1199	ATP-dependent helicase activity
BLEG1_RS09620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BLEG1_RS09625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BLEG1_RS09630	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BLEG1_RS09640	COG0617	tRNA 3'-terminal CCA addition
BLEG1_RS09645	COG0438	transferase activity, transferring glycosyl groups
BLEG1_RS09650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLEG1_RS09655	COG1803	Methylglyoxal synthase
BLEG1_RS09660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLEG1_RS09665	COG1694	Mazg nucleotide pyrophosphohydrolase
BLEG1_RS09670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS09675	COG2738	Putative neutral zinc metallopeptidase
BLEG1_RS09685	COG4347	Protein of unknown function (DUF1405)
BLEG1_RS09695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLEG1_RS09700	COG0723	plastoquinol--plastocyanin reductase activity
BLEG1_RS09710	COG5582	Belongs to the UPF0302 family
BLEG1_RS09715	COG0457	Tetratricopeptide repeat
BLEG1_RS09720	COG0287	Prephenate dehydrogenase
BLEG1_RS09725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLEG1_RS09730	COG0159	tryptophan synthase activity
BLEG1_RS09735	COG0133	tryptophan synthase activity
BLEG1_RS09740	COG0135	phosphoribosylanthranilate isomerase activity
BLEG1_RS09745	COG0134	indole-3-glycerol-phosphate synthase activity
BLEG1_RS09750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLEG1_RS09760	COG4401	Chorismate mutase type I
BLEG1_RS09765	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLEG1_RS09770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLEG1_RS09775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLEG1_RS09780	COG0105	UTP biosynthetic process
BLEG1_RS09785	COG0142	geranyltranstransferase activity
BLEG1_RS09790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BLEG1_RS09795	COG2226	methyltransferase
BLEG1_RS09810	COG0302	gtp cyclohydrolase
BLEG1_RS09815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLEG1_RS09835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BLEG1_RS09840	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BLEG1_RS09845	COG1160	GTP binding
BLEG1_RS09855	COG0539	negative regulation of cytoplasmic translation
BLEG1_RS09860	COG0204	Acyl-transferase
BLEG1_RS09865	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLEG1_RS09870	COG2959	enzyme of heme biosynthesis
BLEG1_RS09875	COG3409	Peptidoglycan-binding domain 1 protein
BLEG1_RS09875	COG3773	Cell wall hydrolase
BLEG1_RS09880	COG1410	methionine synthase
BLEG1_RS09880	COG0646	methionine synthase
BLEG1_RS09885	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLEG1_RS09885	COG0646	methionine synthase
BLEG1_RS09890	COG0626	cystathionine gamma-synthase activity
BLEG1_RS09895	COG2339	peptidase activity
BLEG1_RS09905	COG0492	ferredoxin-NADP+ reductase activity
BLEG1_RS09910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLEG1_RS09920	COG5002	protein histidine kinase activity
BLEG1_RS09925	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS09930	COG4862	establishment of competence for transformation
BLEG1_RS09940	COG1473	amidohydrolase
BLEG1_RS09960	COG1396	sequence-specific DNA binding
BLEG1_RS09975	COG0514	ATP-dependent DNA helicase (RecQ)
BLEG1_RS09980	COG4955	Helix-turn-helix domain
BLEG1_RS09990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLEG1_RS10000	COG1120	ATPase activity
BLEG1_RS10005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS10010	COG5002	protein histidine kinase activity
BLEG1_RS10015	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS10020	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLEG1_RS10025	COG1333	cytochrome c biogenesis protein
BLEG1_RS10030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLEG1_RS10035	COG1187	pseudouridine synthase activity
BLEG1_RS10040	COG0700	Nucleoside recognition
BLEG1_RS10045	COG2715	membrane protein required for spore maturation
BLEG1_RS10050	COG1686	Belongs to the peptidase S11 family
BLEG1_RS10060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLEG1_RS10075	COG2323	membrane
BLEG1_RS10090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLEG1_RS10095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLEG1_RS10100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLEG1_RS10105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLEG1_RS10115	COG2116	formate transmembrane transporter activity
BLEG1_RS10120	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLEG1_RS10125	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLEG1_RS10125	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLEG1_RS10130	COG0307	riboflavin synthase, alpha
BLEG1_RS10145	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLEG1_RS10150	COG0567	Dehydrogenase, E1 component
BLEG1_RS10170	COG1764	response to oxidative stress
BLEG1_RS10175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BLEG1_RS10185	COG0720	synthase
BLEG1_RS10190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLEG1_RS10195	COG2309	aminopeptidase activity
BLEG1_RS10205	COG1254	Belongs to the acylphosphatase family
BLEG1_RS10220	COG1845	cytochrome c oxidase, subunit III
BLEG1_RS10225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLEG1_RS10240	COG0657	acetylesterase activity
BLEG1_RS10245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLEG1_RS10255	COG4841	protein insertion into membrane
BLEG1_RS10260	COG0784	Response regulator, receiver
BLEG1_RS10260	COG0835	chemotaxis
BLEG1_RS10285	COG2200	EAL domain
BLEG1_RS10290	COG2267	carboxylic ester hydrolase activity
BLEG1_RS10305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BLEG1_RS10310	COG0824	Thioesterase
BLEG1_RS10315	COG0464	growth
BLEG1_RS10335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLEG1_RS10355	COG1132	(ABC) transporter
BLEG1_RS10360	COG1132	(ABC) transporter
BLEG1_RS10365	COG3763	UPF0154 protein
BLEG1_RS10375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLEG1_RS10380	COG4224	UPF0291 protein
BLEG1_RS10385	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLEG1_RS10395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLEG1_RS10400	COG2814	Major facilitator Superfamily
BLEG1_RS10410	COG0174	glutamine synthetase
BLEG1_RS10415	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BLEG1_RS10420	COG0464	growth
BLEG1_RS10430	COG1923	regulation of RNA biosynthetic process
BLEG1_RS10435	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLEG1_RS10440	COG2136	Putative SAM-dependent methyltransferase
BLEG1_RS10440	COG2521	methyltransferase
BLEG1_RS10445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLEG1_RS10450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLEG1_RS10460	COG4550	Control of competence regulator ComK, YlbF/YmcA
BLEG1_RS10465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLEG1_RS10475	COG2359	stage V sporulation protein S
BLEG1_RS10480	COG1692	metallophosphoesterase
BLEG1_RS10485	COG1418	mRNA catabolic process
BLEG1_RS10510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLEG1_RS10515	COG0513	Belongs to the DEAD box helicase family
BLEG1_RS10520	COG1058	Belongs to the CinA family
BLEG1_RS10520	COG1546	Belongs to the CinA family
BLEG1_RS10525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLEG1_RS10530	COG1426	Protein conserved in bacteria
BLEG1_RS10545	COG0300	oxidoreductase activity
BLEG1_RS10550	COG0612	Peptidase, M16
BLEG1_RS10555	COG0612	Peptidase, M16
BLEG1_RS10560	COG1674	ftsk spoiiie
BLEG1_RS10570	COG0740	serine-type endopeptidase activity
BLEG1_RS10575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLEG1_RS10585	COG0527	aspartate kinase activity
BLEG1_RS10590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLEG1_RS10595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLEG1_RS10600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLEG1_RS10605	COG1873	PFAM PRC-barrel domain
BLEG1_RS10610	COG0612	Peptidase, M16
BLEG1_RS10615	COG0726	polysaccharide deacetylase
BLEG1_RS10620	COG1185	polyribonucleotide nucleotidyltransferase activity
BLEG1_RS10625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLEG1_RS10630	COG0196	riboflavin kinase activity
BLEG1_RS10635	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLEG1_RS10640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLEG1_RS10645	COG1550	Protein conserved in bacteria
BLEG1_RS10650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLEG1_RS10660	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BLEG1_RS10665	COG0195	Participates in both transcription termination and antitermination
BLEG1_RS10670	COG0779	Required for maturation of 30S ribosomal subunits
BLEG1_RS10675	COG2176	DNA-directed DNA polymerase activity
BLEG1_RS10680	COG0442	prolyl-tRNA aminoacylation
BLEG1_RS10685	COG0750	zinc metalloprotease
BLEG1_RS10690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BLEG1_RS10695	COG4589	Belongs to the CDS family
BLEG1_RS10700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLEG1_RS10705	COG0233	cytoplasmic translational termination
BLEG1_RS10710	COG0528	UMP kinase activity
BLEG1_RS10715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLEG1_RS10720	COG0052	Belongs to the universal ribosomal protein uS2 family
BLEG1_RS10730	COG1191	sigma factor activity
BLEG1_RS10735	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BLEG1_RS10740	COG1776	CheC inhibitor of MCP methylation
BLEG1_RS10745	COG2201	protein-glutamate methylesterase activity
BLEG1_RS10760	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLEG1_RS10765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLEG1_RS10770	COG1684	flagellar biosynthetic protein fliR
BLEG1_RS10775	COG1987	bacterial-type flagellum assembly
BLEG1_RS10780	COG1338	Plays a role in the flagellum-specific transport system
BLEG1_RS10790	COG2201	protein-glutamate methylesterase activity
BLEG1_RS10795	COG1776	CheC inhibitor of MCP methylation
BLEG1_RS10795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLEG1_RS10800	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLEG1_RS10815	COG4786	Flagellar basal body rod
BLEG1_RS10820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BLEG1_RS10840	COG1157	protein secretion by the type III secretion system
BLEG1_RS10845	COG1317	bacterial-type flagellum organization
BLEG1_RS10850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLEG1_RS10855	COG1766	The M ring may be actively involved in energy transduction
BLEG1_RS10860	COG1677	Flagellar hook-basal body complex protein FliE
BLEG1_RS10865	COG1558	bacterial-type flagellum-dependent cell motility
BLEG1_RS10870	COG1815	bacterial-type flagellum-dependent cell motility
BLEG1_RS10875	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLEG1_RS10880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLEG1_RS10885	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLEG1_RS10890	COG4974	Belongs to the 'phage' integrase family
BLEG1_RS10895	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLEG1_RS10900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLEG1_RS10905	COG0758	DNA mediated transformation
BLEG1_RS10910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLEG1_RS10915	COG0045	succinate-CoA ligase (ADP-forming) activity
BLEG1_RS10925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLEG1_RS10945	COG0335	large ribosomal subunit rRNA binding
BLEG1_RS10950	COG0018	arginyl-trna synthetase
BLEG1_RS10955	COG0336	Belongs to the RNA methyltransferase TrmD family
BLEG1_RS10960	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLEG1_RS10970	COG1837	Belongs to the UPF0109 family
BLEG1_RS10975	COG0228	four-way junction DNA binding
BLEG1_RS10980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLEG1_RS10985	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLEG1_RS10990	COG0552	protein localization to endoplasmic reticulum
BLEG1_RS10995	COG1196	nuclear chromosome segregation
BLEG1_RS11005	COG0571	ribonuclease III activity
BLEG1_RS11010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLEG1_RS11015	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS11020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLEG1_RS11025	COG0416	fatty acid biosynthetic process
BLEG1_RS11030	COG1349	DNA-binding transcription factor activity
BLEG1_RS11035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLEG1_RS11040	COG1760	l-serine dehydratase
BLEG1_RS11045	COG1760	l-serine dehydratase
BLEG1_RS11050	COG1307	EDD domain protein, DegV family
BLEG1_RS11055	COG1461	Dihydroxyacetone kinase
BLEG1_RS11060	COG1302	Protein conserved in bacteria
BLEG1_RS11065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLEG1_RS11075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLEG1_RS11080	COG1162	GTPase activity
BLEG1_RS11085	COG2815	serine threonine protein kinase
BLEG1_RS11085	COG0515	serine threonine protein kinase
BLEG1_RS11095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLEG1_RS11095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLEG1_RS11100	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLEG1_RS11105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLEG1_RS11110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLEG1_RS11115	COG1758	RNA polymerase activity
BLEG1_RS11120	COG0194	GDP metabolic process
BLEG1_RS11125	COG2052	Domain of unknown function (DUF370)
BLEG1_RS11130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLEG1_RS11140	COG2226	methyltransferase
BLEG1_RS11145	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLEG1_RS11150	COG0284	orotidine-5'-phosphate decarboxylase activity
BLEG1_RS11155	COG0167	dihydroorotate dehydrogenase activity
BLEG1_RS11160	COG0543	2 iron, 2 sulfur cluster binding
BLEG1_RS11165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLEG1_RS11170	COG0505	Belongs to the CarA family
BLEG1_RS11175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLEG1_RS11180	COG0540	Belongs to the ATCase OTCase family
BLEG1_RS11185	COG2233	PERMEase
BLEG1_RS11190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BLEG1_RS11195	COG0564	pseudouridine synthase activity
BLEG1_RS11200	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLEG1_RS11205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLEG1_RS11210	COG3599	regulation of cell shape
BLEG1_RS11215	COG2302	S4 RNA-binding domain
BLEG1_RS11220	COG0762	integral membrane protein
BLEG1_RS11225	COG1799	cell septum assembly
BLEG1_RS11230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLEG1_RS11235	COG1496	oxidoreductase activity
BLEG1_RS11240	COG1873	PFAM PRC-barrel domain
BLEG1_RS11245	COG1191	sigma factor activity
BLEG1_RS11250	COG1191	sigma factor activity
BLEG1_RS11260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLEG1_RS11265	COG0849	cell division
BLEG1_RS11270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BLEG1_RS11275	COG0772	Belongs to the SEDS family
BLEG1_RS11280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLEG1_RS11285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLEG1_RS11290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLEG1_RS11295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLEG1_RS11300	COG0768	penicillin binding
BLEG1_RS11305	COG0768	penicillin binding
BLEG1_RS11315	COG0275	rRNA processing
BLEG1_RS11320	COG2001	Belongs to the MraZ family
BLEG1_RS11325	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BLEG1_RS11330	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLEG1_RS11335	COG0454	-acetyltransferase
BLEG1_RS11345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLEG1_RS11350	COG1399	metal-binding, possibly nucleic acid-binding protein
BLEG1_RS11360	COG1323	Belongs to the UPF0348 family
BLEG1_RS11365	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLEG1_RS11370	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLEG1_RS11375	COG3314	Sporulation integral membrane protein YlbJ
BLEG1_RS11380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLEG1_RS11385	COG0742	ribosomal rna small subunit methyltransferase
BLEG1_RS11395	COG4471	UPF0298 protein
BLEG1_RS11400	COG3679	Belongs to the UPF0342 family
BLEG1_RS11425	COG2340	Cysteine-rich secretory protein family
BLEG1_RS11440	COG2322	membrane
BLEG1_RS11445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLEG1_RS11450	COG1845	cytochrome c oxidase, subunit III
BLEG1_RS11455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLEG1_RS11460	COG2010	Cytochrome c
BLEG1_RS11460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLEG1_RS11465	COG1612	heme a metabolic process
BLEG1_RS11470	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BLEG1_RS11475	COG4838	Belongs to the UPF0358 family
BLEG1_RS11480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLEG1_RS11485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BLEG1_RS11495	COG1217	gtp-binding protein TYPA
BLEG1_RS11510	COG0483	inositol monophosphate 1-phosphatase activity
BLEG1_RS11520	COG4493	Belongs to the UPF0637 family
BLEG1_RS11525	COG4476	Belongs to the UPF0223 family
BLEG1_RS11530	COG1982	Orn Lys Arg decarboxylase major
BLEG1_RS11535	COG0726	polysaccharide deacetylase
BLEG1_RS11540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS11550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS11555	COG0601	transmembrane transport
BLEG1_RS11565	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS11570	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS11580	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLEG1_RS11585	COG0022	dehydrogenase e1 component
BLEG1_RS11595	COG0497	DNA recombination
BLEG1_RS11605	COG0242	peptide deformylase activity
BLEG1_RS11610	COG5503	Protein of unknown function (DUF1447)
BLEG1_RS11615	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLEG1_RS11620	COG0668	transmembrane transport
BLEG1_RS11630	COG1473	amidohydrolase
BLEG1_RS11635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLEG1_RS11640	COG2171	N-acyltransferase activity
BLEG1_RS11650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BLEG1_RS11655	COG0668	transmembrane transport
BLEG1_RS11665	COG0628	permease
BLEG1_RS11670	COG0702	epimerase
BLEG1_RS11685	COG2608	mercury ion transmembrane transporter activity
BLEG1_RS11690	COG1937	Protein conserved in bacteria
BLEG1_RS11695	COG0561	phosphatase activity
BLEG1_RS11715	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLEG1_RS11720	COG0022	dehydrogenase e1 component
BLEG1_RS11725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLEG1_RS11730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLEG1_RS11740	COG3290	protein histidine kinase activity
BLEG1_RS11740	COG3829	transcription factor binding
BLEG1_RS11755	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS11760	COG0750	zinc metalloprotease
BLEG1_RS11765	COG0497	DNA recombination
BLEG1_RS11770	COG1438	arginine binding
BLEG1_RS11775	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BLEG1_RS11780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLEG1_RS11785	COG0142	geranyltranstransferase activity
BLEG1_RS11790	COG1722	exodeoxyribonuclease VII activity
BLEG1_RS11795	COG1570	exodeoxyribonuclease VII activity
BLEG1_RS11800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLEG1_RS11805	COG1302	Protein conserved in bacteria
BLEG1_RS11810	COG0439	Biotin carboxylase
BLEG1_RS11815	COG0511	ligase activity, forming carbon-carbon bonds
BLEG1_RS11860	COG3854	ATPases associated with a variety of cellular activities
BLEG1_RS11870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLEG1_RS11875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLEG1_RS11880	COG0006	proline dipeptidase activity
BLEG1_RS11895	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLEG1_RS11900	COG1321	iron dependent repressor
BLEG1_RS11905	COG1533	DNA photolyase activity
BLEG1_RS11915	COG3973	AAA domain
BLEG1_RS11920	COG0095	Lipoate-protein ligase
BLEG1_RS11925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLEG1_RS11930	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLEG1_RS11935	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLEG1_RS11940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLEG1_RS11945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLEG1_RS11960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLEG1_RS11995	COG4537	Required for transformation and DNA binding
BLEG1_RS12000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLEG1_RS12050	COG1459	type II secretion system
BLEG1_RS12055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLEG1_RS12060	COG1403	HNH endonuclease
BLEG1_RS12065	COG0210	DNA helicase
BLEG1_RS12070	COG1216	Glycosyl transferase, family 2
BLEG1_RS12070	COG0438	transferase activity, transferring glycosyl groups
BLEG1_RS12075	COG0457	Tetratricopeptide repeat
BLEG1_RS12075	COG0463	Glycosyl transferase, family 2
BLEG1_RS12080	COG0463	Glycosyl transferase, family 2
BLEG1_RS12090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLEG1_RS12090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLEG1_RS12130	COG0564	pseudouridine synthase activity
BLEG1_RS12135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLEG1_RS12140	COG2357	RelA SpoT domain protein
BLEG1_RS12150	COG4116	CYTH
BLEG1_RS12155	COG0741	lytic transglycosylase activity
BLEG1_RS12160	COG2346	COG2346, Truncated hemoglobins
BLEG1_RS12165	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLEG1_RS12175	COG1164	Oligoendopeptidase f
BLEG1_RS12185	COG4862	establishment of competence for transformation
BLEG1_RS12190	COG1393	Belongs to the ArsC family
BLEG1_RS12195	COG0456	acetyltransferase
BLEG1_RS12210	COG1272	protein, Hemolysin III
BLEG1_RS12215	COG1418	mRNA catabolic process
BLEG1_RS12225	COG0180	Tryptophanyl-tRNA synthetase
BLEG1_RS12230	COG1846	Transcriptional regulator
BLEG1_RS12240	COG5504	Zn-dependent protease
BLEG1_RS12245	COG1072	(Pantothenic acid kinase))
BLEG1_RS12250	COG2340	Cysteine-rich secretory protein family
BLEG1_RS12255	COG3773	Cell wall hydrolase
BLEG1_RS12255	COG3409	Peptidoglycan-binding domain 1 protein
BLEG1_RS12265	COG0617	tRNA 3'-terminal CCA addition
BLEG1_RS12265	COG3620	sequence-specific DNA binding
BLEG1_RS12265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLEG1_RS12270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLEG1_RS12275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLEG1_RS12290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BLEG1_RS12310	COG2267	carboxylic ester hydrolase activity
BLEG1_RS12320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLEG1_RS12325	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLEG1_RS12330	COG0505	Belongs to the CarA family
BLEG1_RS12335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLEG1_RS12340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLEG1_RS12345	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLEG1_RS12350	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLEG1_RS12355	COG1999	signal sequence binding
BLEG1_RS12360	COG3336	cytochrome c oxidase
BLEG1_RS12365	COG0561	phosphatase activity
BLEG1_RS12385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLEG1_RS12395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS12400	COG1073	alpha beta
BLEG1_RS12410	COG1054	Belongs to the UPF0176 family
BLEG1_RS12420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLEG1_RS12425	COG1834	amidinotransferase
BLEG1_RS12435	COG0367	asparagine synthase
BLEG1_RS12440	COG0835	chemotaxis
BLEG1_RS12445	COG0643	Histidine kinase
BLEG1_RS12445	COG2198	Histidine kinase
BLEG1_RS12455	COG0704	Plays a role in the regulation of phosphate uptake
BLEG1_RS12460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLEG1_RS12465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLEG1_RS12470	COG0581	inorganic phosphate transmembrane transporter activity
BLEG1_RS12475	COG0573	inorganic phosphate transmembrane transporter activity
BLEG1_RS12480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BLEG1_RS12485	COG2318	DinB family
BLEG1_RS12495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BLEG1_RS12500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLEG1_RS12515	COG1228	amidohydrolase
BLEG1_RS12520	COG2002	toxin-antitoxin pair type II binding
BLEG1_RS12525	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BLEG1_RS12530	COG2868	ribosomal protein
BLEG1_RS12535	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLEG1_RS12540	COG1530	ribonuclease E activity
BLEG1_RS12545	COG1994	Peptidase M50
BLEG1_RS12555	COG0667	Aldo Keto reductase
BLEG1_RS12560	COG1268	BioY protein
BLEG1_RS12565	COG0315	cyclic pyranopterin monophosphate synthase activity
BLEG1_RS12570	COG2894	cell division
BLEG1_RS12575	COG0850	regulation of cytokinetic process
BLEG1_RS12580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BLEG1_RS12585	COG1792	Involved in formation and maintenance of cell shape
BLEG1_RS12590	COG1077	Cell shape determining protein MreB Mrl
BLEG1_RS12595	COG2003	Belongs to the UPF0758 family
BLEG1_RS12600	COG0424	maF-like protein
BLEG1_RS12605	COG0823	Involved in the tonB-independent uptake of proteins
BLEG1_RS12605	COG1506	peptidase
BLEG1_RS12605	COG4946	Tricorn protease homolog
BLEG1_RS12615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BLEG1_RS12620	COG0285	dihydrofolate synthase activity
BLEG1_RS12625	COG0525	valine-tRNA ligase activity
BLEG1_RS12655	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLEG1_RS12660	COG0113	porphobilinogen synthase activity
BLEG1_RS12670	COG0181	hydroxymethylbilane synthase activity
BLEG1_RS12675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BLEG1_RS12680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BLEG1_RS12685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BLEG1_RS12690	COG0470	DNA polymerase III
BLEG1_RS12690	COG1067	ATP-dependent peptidase activity
BLEG1_RS12695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLEG1_RS12700	COG0544	peptidyl-prolyl cis-trans isomerase activity
BLEG1_RS12705	COG1477	protein flavinylation
BLEG1_RS12705	COG0457	Tetratricopeptide repeat
BLEG1_RS12710	COG0066	3-isopropylmalate dehydratase activity
BLEG1_RS12715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLEG1_RS12720	COG0473	3-isopropylmalate dehydrogenase activity
BLEG1_RS12725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLEG1_RS12730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLEG1_RS12735	COG0440	acetolactate synthase activity
BLEG1_RS12740	COG0028	Belongs to the TPP enzyme family
BLEG1_RS12745	COG0129	dihydroxy-acid dehydratase activity
BLEG1_RS12755	COG0110	maltose O-acetyltransferase activity
BLEG1_RS12775	COG0622	Phosphoesterase
BLEG1_RS12780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLEG1_RS12785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BLEG1_RS12790	COG5401	PFAM Sporulation and spore germination
BLEG1_RS12795	COG1054	Belongs to the UPF0176 family
BLEG1_RS12805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLEG1_RS12810	COG1846	Transcriptional regulator
BLEG1_RS12815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLEG1_RS12820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS12825	COG2197	response regulator
BLEG1_RS12830	COG0824	Thioesterase
BLEG1_RS12835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLEG1_RS12840	COG1053	succinate dehydrogenase
BLEG1_RS12845	COG2009	succinate dehydrogenase
BLEG1_RS12855	COG0322	excinuclease ABC activity
BLEG1_RS12860	COG3118	belongs to the thioredoxin family
BLEG1_RS12865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLEG1_RS12870	COG2086	electron transfer activity
BLEG1_RS12875	COG1024	Enoyl-CoA hydratase
BLEG1_RS12880	COG1309	transcriptional regulator
BLEG1_RS12885	COG0318	PFAM AMP-dependent synthetase and ligase
BLEG1_RS12890	COG3766	membrane
BLEG1_RS12895	COG1193	negative regulation of DNA recombination
BLEG1_RS12900	COG1796	DNA polymerase
BLEG1_RS12900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLEG1_RS12905	COG1286	toxin biosynthetic process
BLEG1_RS12910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BLEG1_RS12915	COG0072	phenylalanine-tRNA ligase activity
BLEG1_RS12920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLEG1_RS12925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLEG1_RS12940	COG1363	Peptidase, m42
BLEG1_RS12950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLEG1_RS12955	COG3162	membrane
BLEG1_RS12960	COG0398	Pfam SNARE associated Golgi protein
BLEG1_RS12970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLEG1_RS12975	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLEG1_RS12980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLEG1_RS12985	COG0577	efflux transmembrane transporter activity
BLEG1_RS12990	COG1136	(ABC) transporter
BLEG1_RS12995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLEG1_RS13020	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLEG1_RS13030	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BLEG1_RS13035	COG1484	DNA-dependent DNA replication
BLEG1_RS13040	COG3611	Membrane attachment protein
BLEG1_RS13045	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLEG1_RS13055	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BLEG1_RS13060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLEG1_RS13065	COG0237	dephospho-CoA kinase activity
BLEG1_RS13070	COG1971	Probably functions as a manganese efflux pump
BLEG1_RS13075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BLEG1_RS13080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLEG1_RS13080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLEG1_RS13085	COG5002	protein histidine kinase activity
BLEG1_RS13090	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS13095	COG1522	sequence-specific DNA binding
BLEG1_RS13105	COG0039	L-malate dehydrogenase activity
BLEG1_RS13110	COG0538	isocitrate dehydrogenase activity
BLEG1_RS13115	COG0372	Belongs to the citrate synthase family
BLEG1_RS13120	COG3030	protein affecting phage T7 exclusion by the F plasmid
BLEG1_RS13130	COG0205	6-phosphofructokinase activity
BLEG1_RS13135	COG0825	malonyl-CoA metabolic process
BLEG1_RS13140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLEG1_RS13145	COG2186	Transcriptional regulator
BLEG1_RS13150	COG0281	malic enzyme
BLEG1_RS13155	COG0587	DNA-directed DNA polymerase activity
BLEG1_RS13170	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLEG1_RS13180	COG4109	DRTGG domain
BLEG1_RS13190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLEG1_RS13195	COG0006	proline dipeptidase activity
BLEG1_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS13210	COG0165	Argininosuccinate lyase
BLEG1_RS13215	COG0137	argininosuccinate synthase activity
BLEG1_RS13225	COG3481	metal-dependent phosphohydrolase, HD sub domain
BLEG1_RS13230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLEG1_RS13235	COG0827	DNA restriction-modification system
BLEG1_RS13240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BLEG1_RS13245	COG3874	Sporulation protein YtfJ
BLEG1_RS13255	COG1714	RDD family
BLEG1_RS13260	COG0616	signal peptide processing
BLEG1_RS13265	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BLEG1_RS13275	COG0301	tRNA thio-modification
BLEG1_RS13280	COG1104	cysteine desulfurase activity
BLEG1_RS13285	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLEG1_RS13290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLEG1_RS13295	COG1309	transcriptional regulator
BLEG1_RS13300	COG1956	GAF domain-containing protein
BLEG1_RS13305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLEG1_RS13310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLEG1_RS13320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLEG1_RS13325	COG0454	-acetyltransferase
BLEG1_RS13330	COG0517	IMP dehydrogenase activity
BLEG1_RS13335	COG0123	including yeast histone deacetylase and acetoin utilization protein
BLEG1_RS13340	COG1609	Transcriptional regulator
BLEG1_RS13345	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BLEG1_RS13345	COG1605	Chorismate mutase
BLEG1_RS13350	COG4980	gas vesicle protein
BLEG1_RS13360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLEG1_RS13365	COG1674	ftsk spoiiie
BLEG1_RS13370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLEG1_RS13375	COG4848	Belongs to the UPF0354 family
BLEG1_RS13380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLEG1_RS13395	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BLEG1_RS13400	COG1363	Peptidase, m42
BLEG1_RS13410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BLEG1_RS13420	COG0510	thiamine kinase activity
BLEG1_RS13425	COG0788	formyltetrahydrofolate deformylase activity
BLEG1_RS13430	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS13440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLEG1_RS13445	COG1349	DNA-binding transcription factor activity
BLEG1_RS13450	COG1187	pseudouridine synthase activity
BLEG1_RS13455	COG0772	Belongs to the SEDS family
BLEG1_RS13460	COG0772	Belongs to the SEDS family
BLEG1_RS13465	COG2244	polysaccharide biosynthetic process
BLEG1_RS13470	COG3386	PFAM SMP-30 Gluconolaconase
BLEG1_RS13475	COG0432	Pfam Uncharacterised protein family UPF0047
BLEG1_RS13480	COG1473	amidohydrolase
BLEG1_RS13485	COG2081	HI0933 family
BLEG1_RS13490	COG0495	leucyl-tRNA aminoacylation
BLEG1_RS13495	COG2814	Major facilitator Superfamily
BLEG1_RS13500	COG1242	4 iron, 4 sulfur cluster binding
BLEG1_RS13505	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BLEG1_RS13510	COG0288	reversible hydration of carbon dioxide
BLEG1_RS13520	COG2267	carboxylic ester hydrolase activity
BLEG1_RS13525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BLEG1_RS13530	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLEG1_RS13535	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BLEG1_RS13540	COG1506	peptidase
BLEG1_RS13545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLEG1_RS13550	COG1116	anion transmembrane transporter activity
BLEG1_RS13555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLEG1_RS13560	COG0494	nUDIX hydrolase
BLEG1_RS13565	COG2814	Major facilitator Superfamily
BLEG1_RS13575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLEG1_RS13580	COG1428	Deoxynucleoside kinase
BLEG1_RS13585	COG1428	Deoxynucleoside kinase
BLEG1_RS13595	COG4607	ABC-type enterochelin transport system periplasmic component
BLEG1_RS13600	COG4604	ABC transporter, ATP-binding protein
BLEG1_RS13605	COG4605	iron ion homeostasis
BLEG1_RS13610	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLEG1_RS13615	COG0671	phosphoesterase, PA-phosphatase related
BLEG1_RS13630	COG4846	Membrane protein involved in cytochrome C biogenesis
BLEG1_RS13635	COG0109	protoheme IX farnesyltransferase activity
BLEG1_RS13640	COG1227	inorganic diphosphatase activity
BLEG1_RS13660	COG2610	gluconate transmembrane transporter activity
BLEG1_RS13665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLEG1_RS13670	COG3395	kinase activity
BLEG1_RS13675	COG1349	DNA-binding transcription factor activity
BLEG1_RS13790	COG1396	sequence-specific DNA binding
BLEG1_RS13800	COG1396	sequence-specific DNA binding
BLEG1_RS13995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLEG1_RS14010	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS14015	COG1802	Transcriptional regulator
BLEG1_RS14025	COG0166	Belongs to the GPI family
BLEG1_RS14030	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLEG1_RS14035	COG1979	alcohol dehydrogenase
BLEG1_RS14040	COG2155	Conserved Protein
BLEG1_RS14045	COG1098	S1 RNA binding domain
BLEG1_RS14055	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BLEG1_RS14060	COG0436	Aminotransferase
BLEG1_RS14065	COG1522	sequence-specific DNA binding
BLEG1_RS14070	COG1335	isochorismatase
BLEG1_RS14075	COG1854	S-ribosylhomocysteine lyase activity
BLEG1_RS14080	COG1295	ribonuclease BN
BLEG1_RS14085	COG0776	regulation of translation
BLEG1_RS14090	COG2056	Na+-H+ antiporter family
BLEG1_RS14100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLEG1_RS14105	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BLEG1_RS14110	COG3584	3D domain protein
BLEG1_RS14120	COG1252	NADH dehydrogenase
BLEG1_RS14125	COG0492	ferredoxin-NADP+ reductase activity
BLEG1_RS14130	COG0246	Mannitol dehydrogenase
BLEG1_RS14140	COG3711	transcriptional antiterminator
BLEG1_RS14145	COG2213	PTS system mannitol-specific
BLEG1_RS14150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLEG1_RS14155	COG0765	amino acid transport
BLEG1_RS14160	COG0316	Belongs to the HesB IscA family
BLEG1_RS14165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BLEG1_RS14170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLEG1_RS14180	COG4844	belongs to the
BLEG1_RS14185	COG1252	NADH dehydrogenase
BLEG1_RS14190	COG4837	Protein of unknown function (DUF1462)
BLEG1_RS14195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BLEG1_RS14210	COG0083	homoserine kinase activity
BLEG1_RS14215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BLEG1_RS14220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLEG1_RS14225	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLEG1_RS14235	COG2445	Protein of unknown function DUF86
BLEG1_RS14245	COG4470	Protein conserved in bacteria
BLEG1_RS14255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BLEG1_RS14260	COG0739	heme binding
BLEG1_RS14265	COG1757	Na H antiporter
BLEG1_RS14280	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLEG1_RS14285	COG3377	Domain of unknown function (DUF1805)
BLEG1_RS14290	COG0737	Belongs to the 5'-nucleotidase family
BLEG1_RS14295	COG0730	response to heat
BLEG1_RS14300	COG1801	Protein of unknown function DUF72
BLEG1_RS14305	COG0719	Fe-S assembly protein
BLEG1_RS14310	COG0822	iron-sulfur transferase activity
BLEG1_RS14315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLEG1_RS14320	COG0719	Fe-S assembly protein
BLEG1_RS14325	COG0396	ATPase activity
BLEG1_RS14330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLEG1_RS14335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLEG1_RS14345	COG1464	Belongs to the NlpA lipoprotein family
BLEG1_RS14350	COG2011	ABC-type metal ion transport system permease component
BLEG1_RS14355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLEG1_RS14370	COG0509	glycine decarboxylation via glycine cleavage system
BLEG1_RS14375	COG1393	Belongs to the ArsC family
BLEG1_RS14380	COG1960	acyl-CoA dehydrogenase activity
BLEG1_RS14385	COG0183	Belongs to the thiolase family
BLEG1_RS14390	COG1024	Enoyl-CoA hydratase
BLEG1_RS14390	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLEG1_RS14405	COG0753	catalase activity
BLEG1_RS14415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLEG1_RS14420	COG3314	Sporulation integral membrane protein YlbJ
BLEG1_RS14430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLEG1_RS14435	COG2259	Doxx family
BLEG1_RS14440	COG0557	exoribonuclease II activity
BLEG1_RS14445	COG1647	Serine aminopeptidase, S33
BLEG1_RS14455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLEG1_RS14460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLEG1_RS14470	COG0163	prenyltransferase activity
BLEG1_RS14480	COG0148	phosphopyruvate hydratase activity
BLEG1_RS14485	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLEG1_RS14490	COG0149	triose-phosphate isomerase activity
BLEG1_RS14495	COG0126	phosphoglycerate kinase activity
BLEG1_RS14500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLEG1_RS14515	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLEG1_RS14520	COG0740	serine-type endopeptidase activity
BLEG1_RS14530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS14535	COG1481	regulation of sporulation
BLEG1_RS14540	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BLEG1_RS14545	COG1660	Displays ATPase and GTPase activities
BLEG1_RS14550	COG1051	belongs to the nudix hydrolase family
BLEG1_RS14555	COG0492	ferredoxin-NADP+ reductase activity
BLEG1_RS14565	COG0140	phosphoribosyl-ATP diphosphatase activity
BLEG1_RS14565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLEG1_RS14570	COG0107	imidazoleglycerol-phosphate synthase activity
BLEG1_RS14575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLEG1_RS14580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLEG1_RS14585	COG0131	Imidazoleglycerol-phosphate dehydratase
BLEG1_RS14590	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BLEG1_RS14595	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLEG1_RS14600	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLEG1_RS14605	COG0110	maltose O-acetyltransferase activity
BLEG1_RS14610	COG0546	phosphoglycolate phosphatase activity
BLEG1_RS14615	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLEG1_RS14620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLEG1_RS14625	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLEG1_RS14630	COG1950	PFAM Membrane protein of
BLEG1_RS14635	COG1983	PspC domain protein
BLEG1_RS14640	COG3595	metallopeptidase activity
BLEG1_RS14645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLEG1_RS14650	COG0556	nucleotide-excision repair
BLEG1_RS14665	COG0793	Belongs to the peptidase S41A family
BLEG1_RS14665	COG3409	Peptidoglycan-binding domain 1 protein
BLEG1_RS14670	COG0739	heme binding
BLEG1_RS14675	COG2177	Part of the ABC transporter FtsEX involved in
BLEG1_RS14680	COG2884	Cell division ATP-binding protein ftsE
BLEG1_RS14690	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLEG1_RS14695	COG0653	protein targeting
BLEG1_RS14700	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLEG1_RS14705	COG1278	Cold shock
BLEG1_RS14720	COG1516	flagellar protein fliS
BLEG1_RS14725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BLEG1_RS14735	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BLEG1_RS14740	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BLEG1_RS14745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLEG1_RS14750	COG1256	bacterial-type flagellum assembly
BLEG1_RS14750	COG4786	Flagellar basal body rod
BLEG1_RS14775	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BLEG1_RS14780	COG1307	EDD domain protein, DegV family
BLEG1_RS14795	COG1739	Uncharacterized protein family UPF0029
BLEG1_RS14800	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLEG1_RS14805	COG2860	membrane
BLEG1_RS14820	COG0601	transmembrane transport
BLEG1_RS14825	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS14845	COG4193	domain, Protein
BLEG1_RS14860	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLEG1_RS14860	COG0463	Glycosyl transferase, family 2
BLEG1_RS14865	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLEG1_RS14875	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLEG1_RS14880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLEG1_RS14895	COG1780	Probably involved in ribonucleotide reductase function
BLEG1_RS14900	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLEG1_RS14905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLEG1_RS14910	COG4112	unkown
BLEG1_RS14920	COG1388	LysM domain
BLEG1_RS14920	COG3858	chitin binding
BLEG1_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS14950	COG1725	Transcriptional regulator
BLEG1_RS14955	COG1131	(ABC) transporter
BLEG1_RS14965	COG1959	2 iron, 2 sulfur cluster binding
BLEG1_RS14970	COG1408	metallophosphoesterase
BLEG1_RS14980	COG0561	phosphatase activity
BLEG1_RS14985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLEG1_RS14990	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS15020	COG3275	phosphorelay sensor kinase activity
BLEG1_RS15030	COG1966	Carbon starvation protein
BLEG1_RS15035	COG3961	Belongs to the TPP enzyme family
BLEG1_RS15045	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLEG1_RS15045	COG0519	Catalyzes the synthesis of GMP from XMP
BLEG1_RS15050	COG1305	Transglutaminase-like
BLEG1_RS15055	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BLEG1_RS15060	COG0714	Associated with various cellular activities
BLEG1_RS15070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BLEG1_RS15085	COG0768	penicillin binding
BLEG1_RS15090	COG0778	Nitroreductase
BLEG1_RS15095	COG1126	abc transporter atp-binding protein
BLEG1_RS15100	COG0765	amino acid transport
BLEG1_RS15105	COG0765	amino acid transport
BLEG1_RS15110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLEG1_RS15120	COG0463	Glycosyl transferase, family 2
BLEG1_RS15130	COG4485	Bacterial membrane protein, YfhO
BLEG1_RS15145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BLEG1_RS15150	COG2427	Protein of unknown function (DUF1641)
BLEG1_RS15155	COG3383	formate dehydrogenase (NAD+) activity
BLEG1_RS15160	COG2116	formate transmembrane transporter activity
BLEG1_RS15165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BLEG1_RS15170	COG0314	molybdopterin synthase activity
BLEG1_RS15175	COG1763	Mo-molybdopterin cofactor biosynthetic process
BLEG1_RS15180	COG0303	'Molybdopterin
BLEG1_RS15185	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BLEG1_RS15195	COG0746	molybdenum cofactor guanylyltransferase activity
BLEG1_RS15200	COG0315	cyclic pyranopterin monophosphate synthase activity
BLEG1_RS15205	COG2368	4-hydroxyphenylacetate
BLEG1_RS15210	COG2267	carboxylic ester hydrolase activity
BLEG1_RS15215	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BLEG1_RS15265	COG1279	arginine transmembrane transporter activity
BLEG1_RS15290	COG0459	protein refolding
BLEG1_RS15295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLEG1_RS15300	COG1266	CAAX protease self-immunity
BLEG1_RS15305	COG0371	Dehydrogenase
BLEG1_RS15310	COG1464	Belongs to the NlpA lipoprotein family
BLEG1_RS15315	COG2011	ABC-type metal ion transport system permease component
BLEG1_RS15320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLEG1_RS15330	COG1174	glycine betaine transport
BLEG1_RS15335	COG0517	IMP dehydrogenase activity
BLEG1_RS15335	COG1125	glycine betaine transport
BLEG1_RS15345	COG0805	protein transport
BLEG1_RS15350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLEG1_RS15355	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BLEG1_RS15360	COG0488	(ABC) transporter
BLEG1_RS15365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLEG1_RS15370	COG0456	acetyltransferase
BLEG1_RS15375	COG1214	PFAM Peptidase M22, glycoprotease
BLEG1_RS15380	COG0802	atpase or kinase
BLEG1_RS15385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BLEG1_RS15395	COG0626	cystathionine gamma-synthase activity
BLEG1_RS15400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLEG1_RS15405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLEG1_RS15410	COG1285	pathogenesis
BLEG1_RS15415	COG0586	Pfam SNARE associated Golgi protein
BLEG1_RS15480	COG4152	abc transporter atp-binding protein
BLEG1_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS15500	COG2207	Transcriptional regulator
BLEG1_RS15505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLEG1_RS15510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLEG1_RS15535	COG2409	Drug exporters of the RND superfamily
BLEG1_RS15585	COG3091	SprT-like family
BLEG1_RS15590	COG2183	response to ionizing radiation
BLEG1_RS15600	COG1191	sigma factor activity
BLEG1_RS15605	COG2172	sigma factor antagonist activity
BLEG1_RS15610	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS15615	COG2208	phosphoserine phosphatase activity
BLEG1_RS15620	COG2172	sigma factor antagonist activity
BLEG1_RS15625	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS15630	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS15635	COG2337	Toxic component of a toxin-antitoxin (TA) module
BLEG1_RS15645	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BLEG1_RS15650	COG0736	holo-[acyl-carrier-protein] synthase activity
BLEG1_RS15655	COG0705	Rhomboid family
BLEG1_RS15665	COG1368	sulfuric ester hydrolase activity
BLEG1_RS15670	COG1876	peptidase activity
BLEG1_RS15680	COG5578	integral membrane protein
BLEG1_RS15700	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS15705	COG1082	Xylose isomerase domain protein TIM barrel
BLEG1_RS15710	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS15720	COG1320	monovalent cation:proton antiporter activity
BLEG1_RS15725	COG2212	antiporter activity
BLEG1_RS15730	COG1863	multisubunit Na H antiporter MnhE subunit
BLEG1_RS15735	COG0651	ATP synthesis coupled electron transport
BLEG1_RS15740	COG1006	Multisubunit Na H antiporter MnhC subunit
BLEG1_RS15745	COG2111	Na H antiporter
BLEG1_RS15750	COG2111	Na H antiporter
BLEG1_RS15750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLEG1_RS15755	COG2205	protein histidine kinase activity
BLEG1_RS15765	COG2514	catechol 2,3-dioxygenase activity
BLEG1_RS15770	COG1733	regulation of RNA biosynthetic process
BLEG1_RS15785	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS15790	COG0791	NLP P60 protein
BLEG1_RS15795	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLEG1_RS15800	COG4166	transmembrane transport
BLEG1_RS15805	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS15810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS15815	COG0601	transmembrane transport
BLEG1_RS15820	COG2362	D-Aminopeptidase
BLEG1_RS15825	COG2962	Rard protein
BLEG1_RS15830	COG2706	6-phosphogluconolactonase activity
BLEG1_RS15835	COG0686	Belongs to the AlaDH PNT family
BLEG1_RS15840	COG2508	Transcriptional regulator
BLEG1_RS15840	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLEG1_RS15845	COG0415	Belongs to the DNA photolyase family
BLEG1_RS15855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLEG1_RS15860	COG0531	amino acid
BLEG1_RS15865	COG1876	peptidase activity
BLEG1_RS15880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLEG1_RS15885	COG0596	Alpha beta hydrolase
BLEG1_RS15890	COG0861	Integral membrane protein TerC family
BLEG1_RS15895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLEG1_RS15915	COG1404	Belongs to the peptidase S8 family
BLEG1_RS15920	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BLEG1_RS15930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BLEG1_RS15935	COG3639	organic phosphonate transmembrane transporter activity
BLEG1_RS15940	COG3639	organic phosphonate transmembrane transporter activity
BLEG1_RS15945	COG0604	alcohol dehydrogenase
BLEG1_RS15955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLEG1_RS15975	COG0024	Methionine aminopeptidase
BLEG1_RS15980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLEG1_RS15995	COG1846	Transcriptional regulator
BLEG1_RS16005	COG2239	Acts as a magnesium transporter
BLEG1_RS16010	COG1304	FMN binding
BLEG1_RS16020	COG4977	sequence-specific DNA binding
BLEG1_RS16020	COG1917	Cupin 2, conserved barrel domain protein
BLEG1_RS16025	COG1486	melibiose metabolic process
BLEG1_RS16045	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS16050	COG4209	transmembrane transport
BLEG1_RS16055	COG2207	Transcriptional regulator
BLEG1_RS16055	COG4753	response regulator
BLEG1_RS16060	COG2972	Histidine kinase
BLEG1_RS16065	COG1653	transport
BLEG1_RS16075	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLEG1_RS16080	COG1757	Na H antiporter
BLEG1_RS16085	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS16100	COG2207	Transcriptional regulator
BLEG1_RS16110	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLEG1_RS16115	COG1408	metallophosphoesterase
BLEG1_RS16125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS16130	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BLEG1_RS16140	COG2258	MOSC domain
BLEG1_RS16160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLEG1_RS16170	COG2084	Dehydrogenase
BLEG1_RS16175	COG2610	gluconate transmembrane transporter activity
BLEG1_RS16180	COG1737	Transcriptional regulator
BLEG1_RS16185	COG0191	fructose-bisphosphate aldolase activity
BLEG1_RS16190	COG0697	spore germination
BLEG1_RS16220	COG0577	efflux transmembrane transporter activity
BLEG1_RS16220	COG1136	(ABC) transporter
BLEG1_RS16225	COG3850	Histidine kinase
BLEG1_RS16225	COG5002	protein histidine kinase activity
BLEG1_RS16230	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS16235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLEG1_RS16245	COG1309	transcriptional regulator
BLEG1_RS16250	COG0477	Major facilitator Superfamily
BLEG1_RS16260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLEG1_RS16265	COG2340	Cysteine-rich secretory protein family
BLEG1_RS16285	COG1376	ErfK ybiS ycfS ynhG family protein
BLEG1_RS16310	COG1357	PFAM Pentapeptide repeats (8 copies)
BLEG1_RS16330	COG1113	amino acid transport
BLEG1_RS16340	COG0737	Belongs to the 5'-nucleotidase family
BLEG1_RS16345	COG0438	transferase activity, transferring glycosyl groups
BLEG1_RS16350	COG0438	transferase activity, transferring glycosyl groups
BLEG1_RS16360	COG3397	chitin binding
BLEG1_RS16395	COG5504	Zn-dependent protease
BLEG1_RS16420	COG3842	ATPase activity
BLEG1_RS16425	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS16430	COG1175	transmembrane transport
BLEG1_RS16440	COG0385	Bile acid
BLEG1_RS16450	COG1686	Belongs to the peptidase S11 family
BLEG1_RS16455	COG4509	Sortase family
BLEG1_RS16460	COG1120	ATPase activity
BLEG1_RS16480	COG5386	Cell surface protein
BLEG1_RS16485	COG2329	Antibiotic biosynthesis monooxygenase
BLEG1_RS16500	COG0716	FMN binding
BLEG1_RS16505	COG0551	DNA topoisomerase type I activity
BLEG1_RS16505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLEG1_RS16520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLEG1_RS16530	COG3192	ethanolamine utilization protein
BLEG1_RS16545	COG1621	beta-fructofuranosidase activity
BLEG1_RS16565	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLEG1_RS16570	COG0523	cobalamin synthesis protein
BLEG1_RS16575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLEG1_RS16575	COG0512	Glutamine amidotransferase of anthranilate synthase
BLEG1_RS16590	COG3069	C4-dicarboxylate transmembrane transporter activity
BLEG1_RS16600	COG2226	methyltransferase
BLEG1_RS16625	COG1131	(ABC) transporter
BLEG1_RS16645	COG1302	Protein conserved in bacteria
BLEG1_RS16685	COG0248	Ppx GppA phosphatase
BLEG1_RS16715	COG1132	(ABC) transporter
BLEG1_RS16720	COG1132	(ABC) transporter
BLEG1_RS16740	COG0300	oxidoreductase activity
BLEG1_RS16745	COG1280	lysine exporter protein (LysE YggA)
BLEG1_RS16750	COG1690	Belongs to the RtcB family
BLEG1_RS16755	COG3340	Belongs to the peptidase S51 family
BLEG1_RS16760	COG0346	lactoylglutathione lyase activity
BLEG1_RS16765	COG0400	carboxylic ester hydrolase activity
BLEG1_RS16795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLEG1_RS16815	COG1609	Transcriptional regulator
BLEG1_RS16825	COG1653	transport
BLEG1_RS16830	COG1175	transmembrane transport
BLEG1_RS16840	COG2357	RelA SpoT domain protein
BLEG1_RS16860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BLEG1_RS16870	COG1942	4-Oxalocrotonate Tautomerase
BLEG1_RS16880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLEG1_RS16885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BLEG1_RS16890	COG0583	DNA-binding transcription factor activity
BLEG1_RS16900	COG2261	transglycosylase associated protein
BLEG1_RS16905	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLEG1_RS16920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLEG1_RS16945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLEG1_RS16950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLEG1_RS16955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLEG1_RS16960	COG1132	(ABC) transporter
BLEG1_RS16975	COG0010	Belongs to the arginase family
BLEG1_RS16980	COG0019	diaminopimelate decarboxylase activity
BLEG1_RS16995	COG1595	DNA-templated transcription, initiation
BLEG1_RS17005	COG1511	domain protein
BLEG1_RS17010	COG1674	ftsk spoiiie
BLEG1_RS17015	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLEG1_RS17025	COG4842	Belongs to the WXG100 family
BLEG1_RS17065	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17070	COG1175	transmembrane transport
BLEG1_RS17075	COG2204	response regulator
BLEG1_RS17080	COG2972	Histidine kinase
BLEG1_RS17090	COG2910	NAD(P)H-binding
BLEG1_RS17105	COG1929	Belongs to the glycerate kinase type-1 family
BLEG1_RS17120	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS17125	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLEG1_RS17135	COG2197	response regulator
BLEG1_RS17145	COG1396	sequence-specific DNA binding
BLEG1_RS17155	COG0662	Cupin 2, conserved barrel domain protein
BLEG1_RS17155	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BLEG1_RS17160	COG1091	dTDP-4-dehydrorhamnose reductase activity
BLEG1_RS17175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BLEG1_RS17180	COG2815	serine threonine protein kinase
BLEG1_RS17180	COG0515	serine threonine protein kinase
BLEG1_RS17200	COG1216	Glycosyl transferase, family 2
BLEG1_RS17215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLEG1_RS17220	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLEG1_RS17240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS17240	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS17240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS17245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLEG1_RS17245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS17245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLEG1_RS17250	COG1105	Belongs to the carbohydrate kinase PfkB family
BLEG1_RS17280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLEG1_RS17305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLEG1_RS17305	COG2207	Transcriptional regulator
BLEG1_RS17335	COG1131	(ABC) transporter
BLEG1_RS17355	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17360	COG1175	transmembrane transport
BLEG1_RS17365	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLEG1_RS17375	COG0673	inositol 2-dehydrogenase activity
BLEG1_RS17385	COG2207	Transcriptional regulator
BLEG1_RS17385	COG1917	Cupin 2, conserved barrel domain protein
BLEG1_RS17395	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BLEG1_RS17400	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS17405	COG1349	DNA-binding transcription factor activity
BLEG1_RS17410	COG1070	Carbohydrate kinase
BLEG1_RS17415	COG2115	Belongs to the xylose isomerase family
BLEG1_RS17420	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17425	COG1175	transmembrane transport
BLEG1_RS17435	COG1940	carbohydrate kinase activity
BLEG1_RS17440	COG3507	Belongs to the glycosyl hydrolase 43 family
BLEG1_RS17460	COG1653	transport
BLEG1_RS17465	COG1175	transmembrane transport
BLEG1_RS17470	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17485	COG4193	domain, Protein
BLEG1_RS17505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLEG1_RS17540	COG0318	PFAM AMP-dependent synthetase and ligase
BLEG1_RS17545	COG1309	transcriptional regulator
BLEG1_RS17555	COG4565	transcriptional regulatory protein
BLEG1_RS17560	COG3290	protein histidine kinase activity
BLEG1_RS17580	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17585	COG1175	transmembrane transport
BLEG1_RS17600	COG0671	phosphoesterase, PA-phosphatase related
BLEG1_RS17610	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS17620	COG2207	Transcriptional regulator
BLEG1_RS17625	COG1388	LysM domain
BLEG1_RS17630	COG0753	catalase activity
BLEG1_RS17670	COG1528	Iron-storage protein
BLEG1_RS17695	COG2182	Extracellular solute-binding protein
BLEG1_RS17700	COG1175	transmembrane transport
BLEG1_RS17705	COG3833	ABC-type maltose transport systems, permease component
BLEG1_RS17720	COG2814	Major facilitator Superfamily
BLEG1_RS17725	COG0537	adenosine 5'-monophosphoramidase activity
BLEG1_RS17750	COG3250	beta-galactosidase activity
BLEG1_RS17765	COG1175	transmembrane transport
BLEG1_RS17770	COG0395	ABC-type sugar transport system, permease component
BLEG1_RS17775	COG1657	PFAM Prenyltransferase squalene oxidase
BLEG1_RS17795	COG3181	Tripartite tricarboxylate transporter family receptor
BLEG1_RS17800	COG4565	transcriptional regulatory protein
BLEG1_RS17805	COG3290	protein histidine kinase activity
BLEG1_RS17810	COG0318	PFAM AMP-dependent synthetase and ligase
BLEG1_RS17815	COG4464	protein tyrosine phosphatase activity
BLEG1_RS17820	COG0489	protein tyrosine kinase activity
BLEG1_RS17825	COG3944	biosynthesis protein
BLEG1_RS17830	COG1316	TRANSCRIPTIONal
BLEG1_RS17835	COG2076	Multidrug Resistance protein
BLEG1_RS17840	COG2076	Multidrug Resistance protein
BLEG1_RS17850	COG0702	epimerase
BLEG1_RS17855	COG0772	Belongs to the SEDS family
BLEG1_RS17860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLEG1_RS17875	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLEG1_RS17880	COG0791	NLP P60 protein
BLEG1_RS17880	COG1388	LysM domain
BLEG1_RS17885	COG0010	Belongs to the arginase family
BLEG1_RS17895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLEG1_RS17905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLEG1_RS17930	COG4786	Flagellar basal body rod
BLEG1_RS17935	COG4786	Flagellar basal body rod
BLEG1_RS17940	COG1077	Cell shape determining protein MreB Mrl
BLEG1_RS17945	COG1609	Transcriptional regulator
BLEG1_RS17950	COG0739	heme binding
BLEG1_RS17955	COG2385	sporulation resulting in formation of a cellular spore
BLEG1_RS17960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLEG1_RS17975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLEG1_RS17980	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLEG1_RS17985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLEG1_RS17990	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLEG1_RS17995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLEG1_RS18000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLEG1_RS18005	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLEG1_RS18010	COG0356	it plays a direct role in the translocation of protons across the membrane
BLEG1_RS18025	COG1404	Belongs to the peptidase S8 family
BLEG1_RS18030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLEG1_RS18035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLEG1_RS18040	COG4475	Protein of unknown function (DUF436)
BLEG1_RS18045	COG0698	ribose 5-phosphate isomerase
BLEG1_RS18050	COG0840	transmembrane signaling receptor activity
BLEG1_RS18060	COG1971	Probably functions as a manganese efflux pump
BLEG1_RS18070	COG0009	L-threonylcarbamoyladenylate synthase
BLEG1_RS18090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLEG1_RS18095	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLEG1_RS18105	COG1435	thymidine kinase activity
BLEG1_RS18110	COG0254	rRNA binding
BLEG1_RS18115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BLEG1_RS18120	COG1494	fructose-1,6-bisphosphatase
BLEG1_RS18125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLEG1_RS18130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLEG1_RS18135	COG0191	fructose-bisphosphate aldolase activity
BLEG1_RS18150	COG0504	CTP synthase activity
BLEG1_RS18155	COG3343	RNA polymerase activity
BLEG1_RS18165	COG1960	acyl-CoA dehydrogenase activity
BLEG1_RS18170	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLEG1_RS18175	COG0183	Belongs to the thiolase family
BLEG1_RS18180	COG2181	nitrate reductase activity
BLEG1_RS18180	COG0247	lactate metabolic process
BLEG1_RS18185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLEG1_RS18190	COG2839	Protein conserved in bacteria
BLEG1_RS18195	COG0018	arginyl-trna synthetase
BLEG1_RS18205	COG0010	Belongs to the arginase family
BLEG1_RS18210	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BLEG1_RS18215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLEG1_RS18225	COG1164	Oligoendopeptidase f
BLEG1_RS18245	COG1942	4-Oxalocrotonate Tautomerase
BLEG1_RS18250	COG3465	dGTPase activity
BLEG1_RS18255	COG1078	dGTPase activity
BLEG1_RS18260	COG1301	dicarboxylic acid transport
BLEG1_RS18265	COG0095	Lipoate-protein ligase
BLEG1_RS18270	COG0280	phosphate acetyltransferase
BLEG1_RS18275	COG1024	Enoyl-CoA hydratase
BLEG1_RS18280	COG3253	May function as heme-dependent peroxidase
BLEG1_RS18285	COG0706	membrane insertase activity
BLEG1_RS18295	COG1668	transmembrane transport
BLEG1_RS18300	COG4152	abc transporter atp-binding protein
BLEG1_RS18305	COG3773	Cell wall hydrolase
BLEG1_RS18315	COG2363	Small membrane protein
BLEG1_RS18320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLEG1_RS18320	COG3153	acetyltransferase
BLEG1_RS18340	COG0004	ammonium transporteR
BLEG1_RS18345	COG5577	PFAM Coat F domain
BLEG1_RS18355	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLEG1_RS18360	COG3314	Sporulation integral membrane protein YlbJ
BLEG1_RS18365	COG0840	transmembrane signaling receptor activity
BLEG1_RS18370	COG0351	phosphomethylpyrimidine kinase
BLEG1_RS18375	COG2986	histidine ammonia-lyase
BLEG1_RS18395	COG0513	Belongs to the DEAD box helicase family
BLEG1_RS18405	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BLEG1_RS18410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLEG1_RS18410	COG0723	plastoquinol--plastocyanin reductase activity
BLEG1_RS18430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLEG1_RS18435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLEG1_RS18445	COG3493	citrate carrier protein
BLEG1_RS18460	COG2268	Band 7 protein
BLEG1_RS18465	COG1785	Belongs to the alkaline phosphatase family
BLEG1_RS18470	COG0551	DNA topoisomerase type I activity
BLEG1_RS18470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLEG1_RS18475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BLEG1_RS18485	COG2814	Major facilitator Superfamily
BLEG1_RS18500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLEG1_RS18505	COG1321	iron dependent repressor
BLEG1_RS18505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLEG1_RS18510	COG1121	(ABC) transporter
BLEG1_RS18515	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLEG1_RS18520	COG0561	phosphatase activity
BLEG1_RS18525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLEG1_RS18550	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLEG1_RS18555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLEG1_RS18560	COG2814	Major facilitator Superfamily
BLEG1_RS18630	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS18640	COG3493	citrate carrier protein
BLEG1_RS18645	COG4565	transcriptional regulatory protein
BLEG1_RS18650	COG3290	protein histidine kinase activity
BLEG1_RS18655	COG0753	catalase activity
BLEG1_RS18660	COG1132	(ABC) transporter
BLEG1_RS18670	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLEG1_RS18675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLEG1_RS18680	COG0747	negative chemotaxis
BLEG1_RS18685	COG0601	transmembrane transport
BLEG1_RS18690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS18695	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS18700	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS18735	COG2323	membrane
BLEG1_RS18740	COG1597	lipid kinase activity
BLEG1_RS18745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLEG1_RS18755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLEG1_RS18755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLEG1_RS18770	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BLEG1_RS18785	COG1114	Component of the transport system for branched-chain amino acids
BLEG1_RS18800	COG5002	protein histidine kinase activity
BLEG1_RS18805	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS18815	COG2807	transmembrane transport
BLEG1_RS18820	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS18825	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BLEG1_RS18830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLEG1_RS18835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BLEG1_RS18840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLEG1_RS18845	COG0471	metal ion transport
BLEG1_RS18850	COG4565	transcriptional regulatory protein
BLEG1_RS18855	COG3290	protein histidine kinase activity
BLEG1_RS18860	COG0697	spore germination
BLEG1_RS18905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BLEG1_RS18915	COG1215	transferase activity, transferring glycosyl groups
BLEG1_RS18920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLEG1_RS18935	COG0668	transmembrane transport
BLEG1_RS18940	COG1366	Belongs to the anti-sigma-factor antagonist family
BLEG1_RS18945	COG0813	purine-nucleoside phosphorylase activity
BLEG1_RS18950	COG0346	lactoylglutathione lyase activity
BLEG1_RS18965	COG0577	efflux transmembrane transporter activity
BLEG1_RS18970	COG1136	(ABC) transporter
BLEG1_RS18975	COG0642	Histidine kinase
BLEG1_RS18980	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS18985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BLEG1_RS18990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BLEG1_RS19005	COG1657	PFAM Prenyltransferase squalene oxidase
BLEG1_RS19015	COG4149	molybdate abc transporter
BLEG1_RS19020	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLEG1_RS19035	COG0640	Transcriptional regulator
BLEG1_RS19080	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BLEG1_RS19085	COG1793	dna ligase
BLEG1_RS19085	COG3285	dna ligase
BLEG1_RS19090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLEG1_RS19100	COG2409	Drug exporters of the RND superfamily
BLEG1_RS19110	COG0579	oxidoreductase
BLEG1_RS19130	COG2040	homocysteine
BLEG1_RS19140	COG0583	DNA-binding transcription factor activity
BLEG1_RS19145	COG2814	Major facilitator Superfamily
BLEG1_RS19170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLEG1_RS19185	COG1438	arginine binding
BLEG1_RS19205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLEG1_RS19215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLEG1_RS19220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLEG1_RS19225	COG4853	Protein conserved in bacteria
BLEG1_RS19235	COG5002	protein histidine kinase activity
BLEG1_RS19240	COG0745	RESPONSE REGULATOR receiver
BLEG1_RS19270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLEG1_RS19275	COG0305	Participates in initiation and elongation during chromosome replication
BLEG1_RS19280	COG0359	binds to the 23S rRNA
BLEG1_RS19285	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BLEG1_RS19295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLEG1_RS19300	COG0629	single-stranded DNA binding
BLEG1_RS19305	COG0360	Binds together with S18 to 16S ribosomal RNA
BLEG1_RS19310	COG0012	GTP binding
BLEG1_RS19315	COG4481	Protein conserved in bacteria
BLEG1_RS19320	COG3949	Membrane
BLEG1_RS19330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLEG1_RS19335	COG1475	DNA binding
BLEG1_RS19340	COG1192	Involved in chromosome partitioning
BLEG1_RS19345	COG1475	DNA binding
BLEG1_RS19350	COG0357	Ribosomal RNA small subunit methyltransferase G
BLEG1_RS19355	COG0445	tRNA wobble uridine modification
BLEG1_RS19360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLEG1_RS19365	COG1847	R3H domain protein
BLEG1_RS19370	COG0706	membrane insertase activity
BLEG1_RS19375	COG0594	ribonuclease P activity
BLEG1_RS19380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BLEG1_RS19385	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLEG1_RS19390	COG0592	DNA-directed DNA polymerase activity
BLEG1_RS19395	COG2501	S4 domain
BLEG1_RS19400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLEG1_RS19410	COG0187	DNA topoisomerase II activity
BLEG1_RS19415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLEG1_RS19420	COG1028	Short-chain dehydrogenase reductase Sdr
BLEG1_RS19445	COG0516	GMP reductase activity
BLEG1_RS19445	COG0517	IMP dehydrogenase activity
BLEG1_RS19450	COG1686	Belongs to the peptidase S11 family
BLEG1_RS19460	COG2508	Transcriptional regulator
BLEG1_RS19465	COG0006	proline dipeptidase activity
BLEG1_RS19475	COG1473	amidohydrolase
BLEG1_RS19485	COG1012	belongs to the aldehyde dehydrogenase family
BLEG1_RS19490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLEG1_RS19495	COG0765	amino acid transport
BLEG1_RS19505	COG4608	Belongs to the ABC transporter superfamily
BLEG1_RS19510	COG0444	Belongs to the ABC transporter superfamily
BLEG1_RS19515	COG0601	transmembrane transport
BLEG1_RS19520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLEG1_RS19535	COG0590	tRNA wobble adenosine to inosine editing
BLEG1_RS19540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLEG1_RS19545	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BLEG1_RS19550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLEG1_RS19590	COG1982	Orn Lys Arg decarboxylase major
BLEG1_RS19595	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLEG1_RS19600	COG3870	Protein conserved in bacteria
BLEG1_RS19605	COG0470	DNA polymerase III
BLEG1_RS19610	COG1774	PSP1 C-terminal conserved region
BLEG1_RS19615	COG4467	Involved in initiation control of chromosome replication
BLEG1_RS19620	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BLEG1_RS19625	COG2827	Endonuclease containing a URI domain
BLEG1_RS19630	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLEG1_RS19635	COG2002	toxin-antitoxin pair type II binding
BLEG1_RS19650	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLEG1_RS19650	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLEG1_RS19655	COG0488	(ABC) transporter
BLEG1_RS19670	COG0084	hydrolase, TatD family'
BLEG1_RS19675	COG3583	domain protein
BLEG1_RS19675	COG3584	3D domain protein
BLEG1_RS19680	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLEG1_RS19685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLEG1_RS19695	COG4466	Protein conserved in bacteria
BLEG1_RS19705	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BLEG1_RS19710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLEG1_RS19715	COG0251	oxidation-reduction process
BLEG1_RS19720	COG2088	sporulation resulting in formation of a cellular spore
BLEG1_RS19725	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLEG1_RS19730	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLEG1_RS19735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLEG1_RS19740	COG0193	aminoacyl-tRNA hydrolase activity
BLEG1_RS19750	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLEG1_RS19755	COG2002	toxin-antitoxin pair type II binding
BLEG1_RS19765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLEG1_RS19775	COG2244	polysaccharide biosynthetic process
BLEG1_RS19780	COG3956	TIGRFAM MazG family protein
BLEG1_RS19785	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BLEG1_RS19790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLEG1_RS19795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLEG1_RS19800	COG0492	ferredoxin-NADP+ reductase activity
BLEG1_RS19825	COG1098	S1 RNA binding domain
BLEG1_RS19835	COG2208	phosphoserine phosphatase activity
BLEG1_RS19840	COG2304	oxidoreductase activity
BLEG1_RS19845	COG0515	serine threonine protein kinase
BLEG1_RS19850	COG0037	tRNA processing
BLEG1_RS19855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BLEG1_RS19860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLEG1_RS19865	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BLEG1_RS19870	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BLEG1_RS19875	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLEG1_RS19880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLEG1_RS19885	COG0512	Glutamine amidotransferase of anthranilate synthase
BLEG1_RS19890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLEG1_RS19895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLEG1_RS19900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLEG1_RS19905	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLEG1_RS19910	COG1396	sequence-specific DNA binding
BLEG1_RS19915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLEG1_RS19945	COG5644	endopeptidase inhibitor activity
BLEG1_RS19975	COG3409	Peptidoglycan-binding domain 1 protein
BLEG1_RS19975	COG5632	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS20005	COG3209	COG3209 Rhs family protein
BLEG1_RS20020	COG4585	Histidine kinase
BLEG1_RS20030	COG5434	Belongs to the glycosyl hydrolase 28 family
BLEG1_RS20055	COG0584	glycerophosphoryl diester phosphodiesterase
BLEG1_RS20080	COG3584	3D domain protein
BLEG1_RS20080	COG3583	domain protein
BLEG1_RS20095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLEG1_RS20100	COG1714	RDD family
BLEG1_RS20130	COG1419	protein localization to endoplasmic reticulum
BLEG1_RS20135	COG3190	flagellar
BLEG1_RS20140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLEG1_RS20145	COG1388	LysM domain
BLEG1_RS20145	COG1388	LysM domain
BLEG1_RS20155	COG1396	sequence-specific DNA binding
BLEG1_RS20170	COG0741	lytic transglycosylase activity
BLEG1_RS20170	COG1196	nuclear chromosome segregation
BLEG1_RS20170	COG0739	heme binding
BLEG1_RS20185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLEG1_RS20185	COG2010	Cytochrome c
BLEG1_RS20190	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS20190	COG3103	Sh3 type 3 domain protein
BLEG1_RS20190	COG4991	sh3 domain protein
BLEG1_RS20205	COG5632	N-Acetylmuramoyl-L-alanine amidase
BLEG1_RS20205	COG3409	Peptidoglycan-binding domain 1 protein
BLEG1_RS20235	COG2203	Gaf domain
BLEG1_RS20235	COG4585	Histidine kinase
BLEG1_RS20245	COG0860	N-Acetylmuramoyl-L-alanine amidase