locus-tag	class	description
EJ992_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EJ992_RS00010	COG0592	DNA-directed DNA polymerase activity
EJ992_RS00015	COG2501	S4 domain
EJ992_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EJ992_RS00030	COG0187	DNA topoisomerase II activity
EJ992_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJ992_RS00070	COG0517	IMP dehydrogenase activity
EJ992_RS00070	COG0516	GMP reductase activity
EJ992_RS00075	COG1686	Belongs to the peptidase S11 family
EJ992_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EJ992_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EJ992_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EJ992_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
EJ992_RS00100	COG2610	gluconate transmembrane transporter activity
EJ992_RS00105	COG3835	regulator
EJ992_RS00120	COG1428	Deoxynucleoside kinase
EJ992_RS00125	COG1428	Deoxynucleoside kinase
EJ992_RS00130	COG3858	chitin binding
EJ992_RS00130	COG1388	LysM domain
EJ992_RS00135	COG1335	isochorismatase
EJ992_RS00140	COG0590	tRNA wobble adenosine to inosine editing
EJ992_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EJ992_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EJ992_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EJ992_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EJ992_RS00210	COG3853	Toxic anion resistance protein (TelA)
EJ992_RS00215	COG1982	Orn Lys Arg decarboxylase major
EJ992_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EJ992_RS00225	COG3870	Protein conserved in bacteria
EJ992_RS00230	COG1728	Protein conserved in bacteria
EJ992_RS00235	COG0470	DNA polymerase III
EJ992_RS00240	COG1774	PSP1 C-terminal conserved region
EJ992_RS00245	COG4467	Involved in initiation control of chromosome replication
EJ992_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EJ992_RS00255	COG2827	Endonuclease containing a URI domain
EJ992_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EJ992_RS00265	COG2002	toxin-antitoxin pair type II binding
EJ992_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJ992_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJ992_RS00275	COG0084	hydrolase, TatD family'
EJ992_RS00280	COG3584	3D domain protein
EJ992_RS00280	COG3583	domain protein
EJ992_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EJ992_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EJ992_RS00300	COG4466	Protein conserved in bacteria
EJ992_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EJ992_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJ992_RS00320	COG0251	oxidation-reduction process
EJ992_RS00325	COG2088	sporulation resulting in formation of a cellular spore
EJ992_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EJ992_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EJ992_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EJ992_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
EJ992_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EJ992_RS00360	COG2002	toxin-antitoxin pair type II binding
EJ992_RS00365	COG2244	polysaccharide biosynthetic process
EJ992_RS00370	COG3956	TIGRFAM MazG family protein
EJ992_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EJ992_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EJ992_RS00395	COG1098	S1 RNA binding domain
EJ992_RS00410	COG2208	phosphoserine phosphatase activity
EJ992_RS00415	COG2304	oxidoreductase activity
EJ992_RS00420	COG0515	serine threonine protein kinase
EJ992_RS00425	COG0037	tRNA processing
EJ992_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EJ992_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJ992_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EJ992_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EJ992_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJ992_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJ992_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJ992_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
EJ992_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJ992_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EJ992_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EJ992_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EJ992_RS00495	COG1396	sequence-specific DNA binding
EJ992_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EJ992_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EJ992_RS00585	COG4463	regulation of RNA biosynthetic process
EJ992_RS00590	COG3880	PFAM UvrB UvrC protein
EJ992_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EJ992_RS00600	COG0542	response to heat
EJ992_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EJ992_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EJ992_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
EJ992_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EJ992_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EJ992_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EJ992_RS00635	COG1045	serine acetyltransferase
EJ992_RS00640	COG0215	cysteine-tRNA ligase activity
EJ992_RS00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EJ992_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJ992_RS00655	COG3688	RNA-binding protein containing a PIN domain
EJ992_RS00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJ992_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
EJ992_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EJ992_RS00685	COG0081	regulation of translation
EJ992_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EJ992_RS00695	COG0222	ribosome binding
EJ992_RS00700	COG2813	Specifically methylates the guanine in position
EJ992_RS00705	COG0085	RNA polymerase activity
EJ992_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EJ992_RS00715	COG1358	cellular component organization or biogenesis
EJ992_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EJ992_RS00725	COG0049	tRNA binding
EJ992_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EJ992_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EJ992_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EJ992_RS00750	COG0088	Forms part of the polypeptide exit tunnel
EJ992_RS00755	COG0089	rRNA binding
EJ992_RS00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EJ992_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EJ992_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EJ992_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EJ992_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EJ992_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
EJ992_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EJ992_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EJ992_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EJ992_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EJ992_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJ992_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EJ992_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EJ992_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EJ992_RS00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EJ992_RS00835	COG1841	ribosomal large subunit assembly
EJ992_RS00840	COG0200	Binds to the 23S rRNA
EJ992_RS00845	COG0201	protein transport
EJ992_RS00850	COG0563	adenylate kinase activity
EJ992_RS00855	COG0024	Methionine aminopeptidase
EJ992_RS00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EJ992_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EJ992_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EJ992_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EJ992_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EJ992_RS00885	COG0202	RNA polymerase activity
EJ992_RS00890	COG0203	ribosomal protein L17
EJ992_RS00895	COG1122	ATPase activity
EJ992_RS00900	COG1122	ATPase activity
EJ992_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EJ992_RS00910	COG0101	tRNA pseudouridine synthase activity
EJ992_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EJ992_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EJ992_RS00925	COG2318	DinB family
EJ992_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS00940	COG0489	protein tyrosine kinase activity
EJ992_RS00950	COG2194	sulfuric ester hydrolase activity
EJ992_RS00955	COG0726	polysaccharide deacetylase
EJ992_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJ992_RS00995	COG0385	Bile acid
EJ992_RS01010	COG3876	Protein conserved in bacteria
EJ992_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
EJ992_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJ992_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS01025	COG1263	PTS System
EJ992_RS01030	COG1737	Transcriptional regulator
EJ992_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EJ992_RS01040	COG1683	Conserved Protein
EJ992_RS01075	COG1595	DNA-templated transcription, initiation
EJ992_RS01080	COG5662	AntiSigma factor
EJ992_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EJ992_RS01090	COG4856	YbbR-like protein
EJ992_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJ992_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EJ992_RS01120	COG1725	Transcriptional regulator
EJ992_RS01125	COG0640	Transcriptional regulator
EJ992_RS01130	COG2814	Major facilitator Superfamily
EJ992_RS01140	COG1132	(ABC) transporter
EJ992_RS01145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EJ992_RS01170	COG1011	Hydrolase
EJ992_RS01175	COG1113	amino acid transport
EJ992_RS01180	COG2851	Citrate transporter
EJ992_RS01185	COG3181	Tripartite tricarboxylate transporter family receptor
EJ992_RS01190	COG4565	transcriptional regulatory protein
EJ992_RS01195	COG3290	protein histidine kinase activity
EJ992_RS01205	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJ992_RS01210	COG2211	Major facilitator Superfamily
EJ992_RS01230	COG1331	Highly conserved protein containing a thioredoxin domain
EJ992_RS01235	COG1331	Highly conserved protein containing a thioredoxin domain
EJ992_RS01240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJ992_RS01255	COG3220	belongs to the UPF0276 family
EJ992_RS01270	COG1253	flavin adenine dinucleotide binding
EJ992_RS01275	COG1331	Highly conserved protein containing a thioredoxin domain
EJ992_RS01285	COG0477	Major facilitator Superfamily
EJ992_RS01305	COG1283	sodium-dependent phosphate transmembrane transporter activity
EJ992_RS01310	COG4682	membrane
EJ992_RS01335	COG0697	spore germination
EJ992_RS01360	COG0371	Dehydrogenase
EJ992_RS01365	COG0840	transmembrane signaling receptor activity
EJ992_RS01370	COG4213	ABC transporter substrate-binding protein
EJ992_RS01385	COG4257	antibiotic catabolic process
EJ992_RS01395	COG0833	amino acid
EJ992_RS01400	COG2040	homocysteine
EJ992_RS01410	COG2190	(PTS) system
EJ992_RS01410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS01410	COG1263	PTS System
EJ992_RS01415	COG0789	Transcriptional regulator
EJ992_RS01420	COG2323	membrane
EJ992_RS01425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EJ992_RS01425	COG4451	ribulose bisphosphate carboxylase, small
EJ992_RS01435	COG2205	protein histidine kinase activity
EJ992_RS01440	COG1115	amino acid carrier protein
EJ992_RS01445	COG2066	Belongs to the glutaminase family
EJ992_RS01450	COG4191	Histidine kinase
EJ992_RS01455	COG0784	Response regulator, receiver
EJ992_RS01480	COG3540	Alkaline phosphatase
EJ992_RS01485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJ992_RS01490	COG0805	protein transport
EJ992_RS01495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJ992_RS01500	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS01505	COG2271	Major facilitator Superfamily
EJ992_RS01510	COG4948	Mandelate Racemase Muconate Lactonizing
EJ992_RS01515	COG2186	Transcriptional regulator
EJ992_RS01520	COG2721	sulfolactate sulfo-lyase activity
EJ992_RS01530	COG2205	protein histidine kinase activity
EJ992_RS01535	COG1131	(ABC) transporter
EJ992_RS01560	COG3173	Aminoglycoside phosphotransferase
EJ992_RS01565	COG1846	Transcriptional regulator
EJ992_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS01590	COG0789	Transcriptional regulator
EJ992_RS01615	COG0697	spore germination
EJ992_RS01620	COG1714	RDD family
EJ992_RS01625	COG3012	SEC-C Motif Domain Protein
EJ992_RS01625	COG1405	negative regulation of cell septum assembly
EJ992_RS01630	COG1131	(ABC) transporter
EJ992_RS01655	COG0583	DNA-binding transcription factor activity
EJ992_RS01660	COG1942	4-Oxalocrotonate Tautomerase
EJ992_RS01665	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS01680	COG1288	antiporter activity
EJ992_RS01690	COG0456	acetyltransferase
EJ992_RS01700	COG1164	Oligoendopeptidase f
EJ992_RS01705	COG2261	transglycosylase associated protein
EJ992_RS01715	COG0247	lactate metabolic process
EJ992_RS01720	COG0277	FAD linked oxidase domain protein
EJ992_RS01725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS01730	COG1447	Phosphotransferase system cellobiose-specific component IIA
EJ992_RS01735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS01740	COG1486	melibiose metabolic process
EJ992_RS01745	COG2188	Transcriptional regulator
EJ992_RS01750	COG3394	polysaccharide catabolic process
EJ992_RS01765	COG3591	Belongs to the peptidase S1B family
EJ992_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS01780	COG1595	DNA-templated transcription, initiation
EJ992_RS01790	COG3773	Cell wall hydrolase
EJ992_RS01795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJ992_RS01800	COG3883	PFAM NLP P60 protein
EJ992_RS01800	COG0791	NLP P60 protein
EJ992_RS01810	COG1131	(ABC) transporter
EJ992_RS01815	COG1309	transcriptional regulator
EJ992_RS01835	COG2310	stress, protein
EJ992_RS01840	COG2310	stress, protein
EJ992_RS01845	COG2310	stress, protein
EJ992_RS01850	COG0861	Integral membrane protein TerC family
EJ992_RS01870	COG3853	Toxic anion resistance protein (TelA)
EJ992_RS01875	COG0785	Cytochrome C biogenesis protein
EJ992_RS01885	COG0789	Transcriptional regulator
EJ992_RS01890	COG2223	nitrite transmembrane transporter activity
EJ992_RS01895	COG0039	L-malate dehydrogenase activity
EJ992_RS01900	COG1620	l-lactate permease
EJ992_RS01905	COG1280	lysine exporter protein (LysE YggA)
EJ992_RS01910	COG1113	amino acid transport
EJ992_RS01915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EJ992_RS01920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EJ992_RS01925	COG3541	Predicted nucleotidyltransferase
EJ992_RS01930	COG0506	proline dehydrogenase activity
EJ992_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS01940	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS01945	COG2508	Transcriptional regulator
EJ992_RS01950	COG3689	TIGRFAM TIGR03943 family protein
EJ992_RS01955	COG0701	Predicted permease
EJ992_RS01960	COG3458	cephalosporin-C deacetylase activity
EJ992_RS01980	COG0765	amino acid transport
EJ992_RS01985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJ992_RS01990	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS02000	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS02010	COG3209	COG3209 Rhs family protein
EJ992_RS02020	COG3266	domain, Protein
EJ992_RS02020	COG0515	serine threonine protein kinase
EJ992_RS02030	COG5444	nuclease activity
EJ992_RS02055	COG1176	ABC-type spermidine putrescine transport system, permease component I
EJ992_RS02060	COG1177	transmembrane transport
EJ992_RS02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS02075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS02080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS02085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EJ992_RS02090	COG0697	spore germination
EJ992_RS02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJ992_RS02105	COG2819	hydrolase of the alpha beta superfamily
EJ992_RS02115	COG2364	Membrane
EJ992_RS02125	COG1131	(ABC) transporter
EJ992_RS02150	COG1126	abc transporter atp-binding protein
EJ992_RS02155	COG0765	amino acid transport
EJ992_RS02160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EJ992_RS02165	COG3829	transcription factor binding
EJ992_RS02170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJ992_RS02175	COG0833	amino acid
EJ992_RS02180	COG0010	Belongs to the arginase family
EJ992_RS02185	COG0583	DNA-binding transcription factor activity
EJ992_RS02190	COG0163	prenyltransferase activity
EJ992_RS02195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EJ992_RS02245	COG5444	nuclease activity
EJ992_RS02265	COG2972	Histidine kinase
EJ992_RS02270	COG2207	Transcriptional regulator
EJ992_RS02270	COG4753	response regulator
EJ992_RS02275	COG4213	ABC transporter substrate-binding protein
EJ992_RS02285	COG4214	carbohydrate transport
EJ992_RS02290	COG2271	Major facilitator Superfamily
EJ992_RS02295	COG0456	acetyltransferase
EJ992_RS02295	COG1846	Transcriptional regulator
EJ992_RS02300	COG1874	Beta-galactosidase
EJ992_RS02305	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EJ992_RS02310	COG3104	oligopeptide transport
EJ992_RS02315	COG5434	Belongs to the glycosyl hydrolase 28 family
EJ992_RS02325	COG0697	spore germination
EJ992_RS02335	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EJ992_RS02340	COG0789	Transcriptional regulator
EJ992_RS02345	COG1136	(ABC) transporter
EJ992_RS02350	COG0577	efflux transmembrane transporter activity
EJ992_RS02355	COG0745	RESPONSE REGULATOR receiver
EJ992_RS02360	COG3850	Histidine kinase
EJ992_RS02360	COG5002	protein histidine kinase activity
EJ992_RS02365	COG0840	transmembrane signaling receptor activity
EJ992_RS02370	COG0527	aspartate kinase activity
EJ992_RS02375	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS02380	COG4605	iron ion homeostasis
EJ992_RS02385	COG4604	ABC transporter, ATP-binding protein
EJ992_RS02390	COG4607	ABC-type enterochelin transport system periplasmic component
EJ992_RS02395	COG2814	Major facilitator Superfamily
EJ992_RS02400	COG1309	transcriptional regulator
EJ992_RS02410	COG0778	Nitroreductase
EJ992_RS02415	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EJ992_RS02420	COG0640	Transcriptional regulator
EJ992_RS02425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJ992_RS02430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EJ992_RS02435	COG0531	amino acid
EJ992_RS02440	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS02445	COG0697	spore germination
EJ992_RS02455	COG4549	nuclear export factor GLE1
EJ992_RS02460	COG1276	copper resistance
EJ992_RS02460	COG2372	response to copper ion
EJ992_RS02465	COG1349	DNA-binding transcription factor activity
EJ992_RS02470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJ992_RS02475	COG0243	molybdopterin cofactor binding
EJ992_RS02480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJ992_RS02485	COG2146	nitrite reductase [NAD(P)H] activity
EJ992_RS02490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJ992_RS02490	COG1587	Uroporphyrinogen-III synthase
EJ992_RS02495	COG1802	Transcriptional regulator
EJ992_RS02500	COG0471	metal ion transport
EJ992_RS02505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EJ992_RS02510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EJ992_RS02525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS02540	COG3959	Transketolase, thiamine diphosphate binding domain
EJ992_RS02545	COG3958	Transketolase
EJ992_RS02550	COG0561	phosphatase activity
EJ992_RS02555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EJ992_RS02560	COG1914	H( )-stimulated, divalent metal cation uptake system
EJ992_RS02565	COG4336	lyase activity
EJ992_RS02570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EJ992_RS02575	COG1984	allophanate hydrolase subunit 2
EJ992_RS02580	COG1414	Transcriptional regulator
EJ992_RS02585	COG2755	lipolytic protein G-D-S-L family
EJ992_RS02590	COG2213	PTS system mannitol-specific
EJ992_RS02595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS02600	COG0246	Mannitol dehydrogenase
EJ992_RS02605	COG3711	transcriptional antiterminator
EJ992_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS02615	COG1917	Cupin 2, conserved barrel domain protein
EJ992_RS02625	COG3871	stress protein (general stress protein 26)
EJ992_RS02640	COG2814	Major facilitator Superfamily
EJ992_RS02650	COG1522	sequence-specific DNA binding
EJ992_RS02655	COG0551	DNA topoisomerase type I activity
EJ992_RS02655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJ992_RS02660	COG0531	amino acid
EJ992_RS02665	COG0028	Belongs to the TPP enzyme family
EJ992_RS02670	COG3397	chitin binding
EJ992_RS02685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS02690	COG1914	H( )-stimulated, divalent metal cation uptake system
EJ992_RS02695	COG2261	transglycosylase associated protein
EJ992_RS02700	COG1027	Aspartate ammonia-lyase
EJ992_RS02705	COG1819	glycosyl
EJ992_RS02710	COG4876	unkown
EJ992_RS02715	COG2217	Heavy metal translocating P-type atpase
EJ992_RS02725	COG0662	Cupin 2, conserved barrel domain protein
EJ992_RS02730	COG3729	General stress protein
EJ992_RS02735	COG0628	permease
EJ992_RS02740	COG1301	dicarboxylic acid transport
EJ992_RS02745	COG1131	(ABC) transporter
EJ992_RS02750	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EJ992_RS02760	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS02775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS02780	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJ992_RS02785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EJ992_RS02795	COG0513	Belongs to the DEAD box helicase family
EJ992_RS02800	COG3402	PFAM membrane-flanked domain
EJ992_RS02805	COG3428	Bacterial PH domain
EJ992_RS02810	COG0705	Rhomboid family
EJ992_RS02815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EJ992_RS02820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EJ992_RS02825	COG0864	Transcriptional regulator
EJ992_RS02830	COG2337	Toxic component of a toxin-antitoxin (TA) module
EJ992_RS02835	COG1366	Belongs to the anti-sigma-factor antagonist family
EJ992_RS02840	COG1366	Belongs to the anti-sigma-factor antagonist family
EJ992_RS02845	COG2172	sigma factor antagonist activity
EJ992_RS02850	COG2208	phosphoserine phosphatase activity
EJ992_RS02860	COG2172	sigma factor antagonist activity
EJ992_RS02865	COG1191	sigma factor activity
EJ992_RS02870	COG2208	phosphoserine phosphatase activity
EJ992_RS02875	COG2183	response to ionizing radiation
EJ992_RS02880	COG1309	transcriptional regulator
EJ992_RS02885	COG1033	growth of symbiont in host cell
EJ992_RS02885	COG2409	Drug exporters of the RND superfamily
EJ992_RS02895	COG3091	SprT-like family
EJ992_RS02935	COG0697	spore germination
EJ992_RS02945	COG1476	TRANSCRIPTIONal
EJ992_RS02950	COG3239	Fatty acid desaturase
EJ992_RS02955	COG1278	Cold shock
EJ992_RS02960	COG1063	alcohol dehydrogenase
EJ992_RS02970	COG2364	Membrane
EJ992_RS02975	COG1846	Transcriptional regulator
EJ992_RS02980	COG0456	acetyltransferase
EJ992_RS02985	COG2808	Putative FMN-binding domain
EJ992_RS02995	COG1733	regulation of RNA biosynthetic process
EJ992_RS03000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS03010	COG0583	DNA-binding transcription factor activity
EJ992_RS03025	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EJ992_RS03030	COG1113	amino acid transport
EJ992_RS03045	COG1595	DNA-templated transcription, initiation
EJ992_RS03055	COG2755	lipolytic protein G-D-S-L family
EJ992_RS03055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EJ992_RS03060	COG2814	Major facilitator Superfamily
EJ992_RS03065	COG0745	RESPONSE REGULATOR receiver
EJ992_RS03065	COG2972	Histidine kinase
EJ992_RS03070	COG3279	Response regulator of the LytR AlgR family
EJ992_RS03080	COG3764	Sortase (surface protein transpeptidase)
EJ992_RS03090	COG2814	Major facilitator Superfamily
EJ992_RS03130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EJ992_RS03135	COG0802	atpase or kinase
EJ992_RS03140	COG1214	PFAM Peptidase M22, glycoprotease
EJ992_RS03145	COG0456	acetyltransferase
EJ992_RS03150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EJ992_RS03155	COG0488	(ABC) transporter
EJ992_RS03160	COG0315	cyclic pyranopterin monophosphate synthase activity
EJ992_RS03165	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EJ992_RS03170	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EJ992_RS03175	COG0805	protein transport
EJ992_RS03185	COG1266	CAAX protease self-immunity
EJ992_RS03190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EJ992_RS03195	COG0459	protein refolding
EJ992_RS03225	COG2720	vancomycin resistance protein
EJ992_RS03240	COG2135	peptidase activity
EJ992_RS03250	COG1309	transcriptional regulator
EJ992_RS03255	COG3848	Pyruvate phosphate dikinase
EJ992_RS03255	COG0574	Belongs to the PEP-utilizing enzyme family
EJ992_RS03265	COG3189	MarR family transcriptional regulator
EJ992_RS03270	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EJ992_RS03275	COG2272	Belongs to the type-B carboxylesterase lipase family
EJ992_RS03280	COG2814	Major facilitator Superfamily
EJ992_RS03285	COG1842	Phage shock protein A
EJ992_RS03290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EJ992_RS03295	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EJ992_RS03300	COG4260	virion core protein, lumpy skin disease virus
EJ992_RS03310	COG1378	Sugar-specific transcriptional regulator TrmB
EJ992_RS03315	COG1280	lysine exporter protein (LysE YggA)
EJ992_RS03320	COG3339	Conserved Protein
EJ992_RS03325	COG0772	Belongs to the SEDS family
EJ992_RS03330	COG0772	Belongs to the SEDS family
EJ992_RS03355	COG0726	polysaccharide deacetylase
EJ992_RS03365	COG1609	Transcriptional regulator
EJ992_RS03370	COG0366	Alpha amylase catalytic
EJ992_RS03375	COG2182	Extracellular solute-binding protein
EJ992_RS03380	COG1175	transmembrane transport
EJ992_RS03385	COG3833	ABC-type maltose transport systems, permease component
EJ992_RS03390	COG5521	maltodextrose utilization protein MalA
EJ992_RS03395	COG1554	hydrolase, family 65, central catalytic
EJ992_RS03400	COG0366	Alpha amylase catalytic
EJ992_RS03405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJ992_RS03410	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJ992_RS03415	COG1846	Transcriptional regulator
EJ992_RS03430	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EJ992_RS03435	COG0823	Involved in the tonB-independent uptake of proteins
EJ992_RS03465	COG0702	epimerase
EJ992_RS03475	COG2132	Multicopper oxidase
EJ992_RS03490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EJ992_RS03495	COG0714	Associated with various cellular activities
EJ992_RS03500	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EJ992_RS03505	COG1305	Transglutaminase-like
EJ992_RS03510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EJ992_RS03510	COG0519	Catalyzes the synthesis of GMP from XMP
EJ992_RS03520	COG2252	PERMEase
EJ992_RS03535	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EJ992_RS03545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EJ992_RS03550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EJ992_RS03555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EJ992_RS03560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EJ992_RS03565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJ992_RS03570	COG0047	phosphoribosylformylglycinamidine synthase activity
EJ992_RS03575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EJ992_RS03580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EJ992_RS03585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EJ992_RS03590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EJ992_RS03595	COG0138	bifunctional purine biosynthesis protein purh
EJ992_RS03600	COG0151	Belongs to the GarS family
EJ992_RS03610	COG2124	cytochrome p450
EJ992_RS03630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EJ992_RS03635	COG1470	cell adhesion involved in biofilm formation
EJ992_RS03640	COG4496	protein, YerC YecD
EJ992_RS03645	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EJ992_RS03650	COG0210	DNA helicase
EJ992_RS03655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EJ992_RS03660	COG4851	CamS sex pheromone cAM373 precursor
EJ992_RS03665	COG2188	Transcriptional regulator
EJ992_RS03685	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EJ992_RS03690	COG0626	cystathionine gamma-synthase activity
EJ992_RS03695	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EJ992_RS03700	COG3457	Alanine racemase
EJ992_RS03705	COG0363	glucosamine-6-phosphate deaminase activity
EJ992_RS03710	COG1285	pathogenesis
EJ992_RS03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS03720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJ992_RS03725	COG0154	amidase activity
EJ992_RS03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EJ992_RS03745	COG4124	Belongs to the glycosyl hydrolase 26 family
EJ992_RS03750	COG1309	transcriptional regulator
EJ992_RS03755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EJ992_RS03765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS03770	COG1957	nucleoside hydrolase
EJ992_RS03775	COG1597	lipid kinase activity
EJ992_RS03780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EJ992_RS03800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EJ992_RS03810	COG1263	PTS System
EJ992_RS03810	COG2190	(PTS) system
EJ992_RS03810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS03815	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS03820	COG3711	transcriptional antiterminator
EJ992_RS03825	COG0457	Tetratricopeptide repeat
EJ992_RS03840	COG0217	transcriptional regulatory protein
EJ992_RS03855	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS03860	COG0840	transmembrane signaling receptor activity
EJ992_RS03865	COG0471	metal ion transport
EJ992_RS03870	COG0488	(ABC) transporter
EJ992_RS03880	COG1469	GTP cyclohydrolase I activity
EJ992_RS03895	COG0523	cobalamin synthesis protein
EJ992_RS03900	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EJ992_RS03905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJ992_RS03910	COG0156	8-amino-7-oxononanoate synthase activity
EJ992_RS03915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EJ992_RS03920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EJ992_RS03925	COG2124	cytochrome p450
EJ992_RS03935	COG0789	Transcriptional regulator
EJ992_RS03940	COG2814	Major facilitator Superfamily
EJ992_RS03945	COG0488	(ABC) transporter
EJ992_RS03950	COG0513	Belongs to the DEAD box helicase family
EJ992_RS03955	COG2130	NADP-dependent
EJ992_RS03970	COG0471	metal ion transport
EJ992_RS03985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS03995	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EJ992_RS04000	COG5658	integral membrane protein
EJ992_RS04005	COG0640	Transcriptional regulator
EJ992_RS04010	COG1254	Belongs to the acylphosphatase family
EJ992_RS04015	COG2258	MOSC domain
EJ992_RS04025	COG0024	Methionine aminopeptidase
EJ992_RS04030	COG1368	sulfuric ester hydrolase activity
EJ992_RS04040	COG1115	amino acid carrier protein
EJ992_RS04045	COG1263	PTS System
EJ992_RS04045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS04050	COG0366	Alpha amylase catalytic
EJ992_RS04055	COG2188	Transcriptional regulator
EJ992_RS04075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJ992_RS04080	COG1045	serine acetyltransferase
EJ992_RS04085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJ992_RS04095	COG1215	transferase activity, transferring glycosyl groups
EJ992_RS04100	COG0457	Tetratricopeptide repeat
EJ992_RS04100	COG0463	Glycosyl transferase, family 2
EJ992_RS04110	COG0673	inositol 2-dehydrogenase activity
EJ992_RS04120	COG0657	acetylesterase activity
EJ992_RS04125	COG1733	regulation of RNA biosynthetic process
EJ992_RS04130	COG0778	Nitroreductase
EJ992_RS04135	COG0737	Belongs to the 5'-nucleotidase family
EJ992_RS04140	COG0693	protein deglycase activity
EJ992_RS04145	COG4840	Belongs to the UPF0435 family
EJ992_RS04150	COG1115	amino acid carrier protein
EJ992_RS04155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJ992_RS04160	COG4980	gas vesicle protein
EJ992_RS04165	COG1295	ribonuclease BN
EJ992_RS04170	COG0477	Major facilitator Superfamily
EJ992_RS04180	COG0387	Pfam Sodium calcium exchanger
EJ992_RS04190	COG0535	radical SAM domain protein
EJ992_RS04200	COG0726	polysaccharide deacetylase
EJ992_RS04205	COG0371	Dehydrogenase
EJ992_RS04215	COG0598	Magnesium transport protein CorA
EJ992_RS04220	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EJ992_RS04225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EJ992_RS04230	COG4637	Psort location Cytoplasmic, score
EJ992_RS04255	COG1819	glycosyl
EJ992_RS04265	COG0477	Major facilitator Superfamily
EJ992_RS04270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS04270	COG1263	PTS System
EJ992_RS04275	COG3711	transcriptional antiterminator
EJ992_RS04280	COG0288	reversible hydration of carbon dioxide
EJ992_RS04285	COG3002	Belongs to the UPF0753 family
EJ992_RS04290	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJ992_RS04295	COG5609	conserved protein (DUF2294)
EJ992_RS04305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJ992_RS04310	COG0022	dehydrogenase e1 component
EJ992_RS04315	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJ992_RS04320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJ992_RS04325	COG3284	Transcriptional regulator
EJ992_RS04330	COG1742	UPF0060 membrane protein
EJ992_RS04335	COG1486	melibiose metabolic process
EJ992_RS04340	COG1737	Transcriptional regulator
EJ992_RS04345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS04345	COG1263	PTS System
EJ992_RS04360	COG1733	regulation of RNA biosynthetic process
EJ992_RS04365	COG2259	Doxx family
EJ992_RS04370	COG2514	catechol 2,3-dioxygenase activity
EJ992_RS04380	COG3507	Belongs to the glycosyl hydrolase 43 family
EJ992_RS04385	COG2207	Transcriptional regulator
EJ992_RS04385	COG1917	Cupin 2, conserved barrel domain protein
EJ992_RS04390	COG1653	transport
EJ992_RS04395	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS04400	COG1051	belongs to the nudix hydrolase family
EJ992_RS04410	COG0392	lysyltransferase activity
EJ992_RS04410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EJ992_RS04415	COG0384	phenazine biosynthesis protein PhzF
EJ992_RS04420	COG0778	Nitroreductase
EJ992_RS04440	COG1090	epimerase
EJ992_RS04445	COG2137	regulation of response to DNA damage stimulus
EJ992_RS04475	COG0463	Glycosyl transferase, family 2
EJ992_RS04485	COG4485	Bacterial membrane protein, YfhO
EJ992_RS04490	COG1988	membrane-bound metal-dependent
EJ992_RS04495	COG1194	a g-specific adenine glycosylase
EJ992_RS04505	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS04520	COG3557	Belongs to the UPF0374 family
EJ992_RS04525	COG1132	(ABC) transporter
EJ992_RS04530	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS04535	COG4608	Belongs to the ABC transporter superfamily
EJ992_RS04540	COG0747	negative chemotaxis
EJ992_RS04545	COG0601	transmembrane transport
EJ992_RS04550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS04555	COG4129	membrane
EJ992_RS04560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EJ992_RS04565	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EJ992_RS04570	COG0735	belongs to the Fur family
EJ992_RS04680	COG0457	Tetratricopeptide repeat
EJ992_RS04725	COG5444	nuclease activity
EJ992_RS04740	COG5444	nuclease activity
EJ992_RS04745	COG0457	Tetratricopeptide repeat
EJ992_RS04750	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJ992_RS04760	COG0710	3-dehydroquinate dehydratase activity
EJ992_RS04765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EJ992_RS04770	COG1116	anion transmembrane transporter activity
EJ992_RS04775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJ992_RS04780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJ992_RS04785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJ992_RS04795	COG1476	TRANSCRIPTIONal
EJ992_RS04805	COG1131	(ABC) transporter
EJ992_RS04825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJ992_RS04835	COG3382	B3 4 domain protein
EJ992_RS04840	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EJ992_RS04850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EJ992_RS04855	COG0789	Transcriptional regulator
EJ992_RS04860	COG1664	Polymer-forming cytoskeletal
EJ992_RS04870	COG2766	serine protein kinase
EJ992_RS04875	COG2718	Belongs to the UPF0229 family
EJ992_RS04880	COG1566	PFAM secretion protein HlyD family protein
EJ992_RS04885	COG2814	Major facilitator Superfamily
EJ992_RS04890	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS04905	COG1131	(ABC) transporter
EJ992_RS04910	COG1131	(ABC) transporter
EJ992_RS04915	COG1131	(ABC) transporter
EJ992_RS04920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EJ992_RS04925	COG1278	Cold shock
EJ992_RS04930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EJ992_RS04935	COG2011	ABC-type metal ion transport system permease component
EJ992_RS04940	COG1464	Belongs to the NlpA lipoprotein family
EJ992_RS04945	COG1823	symporter activity
EJ992_RS04970	COG5577	PFAM Coat F domain
EJ992_RS04975	COG5002	protein histidine kinase activity
EJ992_RS04980	COG4085	toxin activity
EJ992_RS04980	COG1525	nuclease
EJ992_RS04980	COG0737	Belongs to the 5'-nucleotidase family
EJ992_RS04985	COG3764	Sortase (surface protein transpeptidase)
EJ992_RS04990	COG0564	pseudouridine synthase activity
EJ992_RS05000	COG0517	IMP dehydrogenase activity
EJ992_RS05005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EJ992_RS05010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJ992_RS05010	COG3153	acetyltransferase
EJ992_RS05015	COG0488	(ABC) transporter
EJ992_RS05025	COG2116	formate transmembrane transporter activity
EJ992_RS05030	COG0679	Auxin Efflux Carrier
EJ992_RS05035	COG0604	alcohol dehydrogenase
EJ992_RS05040	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EJ992_RS05045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EJ992_RS05050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EJ992_RS05055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EJ992_RS05060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EJ992_RS05075	COG4585	Histidine kinase
EJ992_RS05075	COG2203	Gaf domain
EJ992_RS05080	COG2197	response regulator
EJ992_RS05085	COG0431	NADPH-dependent FMN reductase
EJ992_RS05100	COG1959	2 iron, 2 sulfur cluster binding
EJ992_RS05105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EJ992_RS05105	COG1017	nitric oxide dioxygenase activity
EJ992_RS05110	COG2719	SpoVR family
EJ992_RS05115	COG1388	LysM domain
EJ992_RS05115	COG0791	NLP P60 protein
EJ992_RS05120	COG0583	DNA-binding transcription factor activity
EJ992_RS05125	COG0372	Belongs to the citrate synthase family
EJ992_RS05130	COG2133	pyrroloquinoline quinone binding
EJ992_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS05140	COG0733	neurotransmitter:sodium symporter activity
EJ992_RS05150	COG2207	Transcriptional regulator
EJ992_RS05150	COG3708	Transcriptional regulator
EJ992_RS05155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJ992_RS05175	COG1595	DNA-templated transcription, initiation
EJ992_RS05180	COG0662	Cupin 2, conserved barrel domain protein
EJ992_RS05190	COG0204	Acyl-transferase
EJ992_RS05195	COG3152	Membrane
EJ992_RS05210	COG1253	flavin adenine dinucleotide binding
EJ992_RS05215	COG0789	Transcriptional regulator
EJ992_RS05220	COG1253	flavin adenine dinucleotide binding
EJ992_RS05240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJ992_RS05245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EJ992_RS05250	COG0584	glycerophosphoryl diester phosphodiesterase
EJ992_RS05260	COG0668	transmembrane transport
EJ992_RS05265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EJ992_RS05275	COG0726	polysaccharide deacetylase
EJ992_RS05285	COG1757	Na H antiporter
EJ992_RS05290	COG2017	converts alpha-aldose to the beta-anomer
EJ992_RS05315	COG0589	response to stress
EJ992_RS05320	COG1132	(ABC) transporter
EJ992_RS05325	COG1132	(ABC) transporter
EJ992_RS05330	COG0702	epimerase
EJ992_RS05345	COG3842	ATPase activity
EJ992_RS05350	COG2508	Transcriptional regulator
EJ992_RS05360	COG0189	ligase activity
EJ992_RS05365	COG0189	ligase activity
EJ992_RS05370	COG4399	Belongs to the UPF0754 family
EJ992_RS05375	COG3679	Belongs to the UPF0342 family
EJ992_RS05385	COG0561	phosphatase activity
EJ992_RS05390	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EJ992_RS05395	COG1024	Enoyl-CoA hydratase
EJ992_RS05400	COG0457	Tetratricopeptide repeat
EJ992_RS05415	COG4152	abc transporter atp-binding protein
EJ992_RS05420	COG1668	transmembrane transport
EJ992_RS05425	COG0420	3'-5' exonuclease activity
EJ992_RS05430	COG4717	serine-type aminopeptidase activity
EJ992_RS05435	COG3481	metal-dependent phosphohydrolase, HD sub domain
EJ992_RS05445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EJ992_RS05475	COG1846	Transcriptional regulator
EJ992_RS05480	COG4980	gas vesicle protein
EJ992_RS05495	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EJ992_RS05500	COG0537	adenosine 5'-monophosphoramidase activity
EJ992_RS05505	COG1131	(ABC) transporter
EJ992_RS05510	COG4473	ABC transporter
EJ992_RS05520	COG1473	amidohydrolase
EJ992_RS05525	COG3069	C4-dicarboxylate transmembrane transporter activity
EJ992_RS05530	COG2329	Antibiotic biosynthesis monooxygenase
EJ992_RS05535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJ992_RS05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EJ992_RS05545	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EJ992_RS05550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EJ992_RS05555	COG1309	transcriptional regulator
EJ992_RS05560	COG1511	domain protein
EJ992_RS05565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJ992_RS05570	COG1363	Peptidase, m42
EJ992_RS05580	COG1301	dicarboxylic acid transport
EJ992_RS05590	COG1234	tRNA 3'-trailer cleavage
EJ992_RS05595	COG0095	Lipoate-protein ligase
EJ992_RS05600	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS05610	COG1396	sequence-specific DNA binding
EJ992_RS05625	COG0501	Belongs to the peptidase M48B family
EJ992_RS05635	COG0697	spore germination
EJ992_RS05640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EJ992_RS05645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS05650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS05655	COG0406	alpha-ribazole phosphatase activity
EJ992_RS05660	COG0840	transmembrane signaling receptor activity
EJ992_RS05665	COG0723	plastoquinol--plastocyanin reductase activity
EJ992_RS05665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJ992_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS05680	COG4903	ComK protein
EJ992_RS05690	COG0398	Pfam SNARE associated Golgi protein
EJ992_RS05695	COG0681	Belongs to the peptidase S26 family
EJ992_RS05700	COG1404	Belongs to the peptidase S8 family
EJ992_RS05710	COG2508	Transcriptional regulator
EJ992_RS05720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJ992_RS05725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJ992_RS05730	COG3257	ureidoglycine aminohydrolase activity
EJ992_RS05735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EJ992_RS05740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EJ992_RS05745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJ992_RS05750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJ992_RS05760	COG0549	Belongs to the carbamate kinase family
EJ992_RS05765	COG2814	Major facilitator Superfamily
EJ992_RS05775	COG0457	Tetratricopeptide repeat
EJ992_RS05795	COG1609	Transcriptional regulator
EJ992_RS05800	COG1653	transport
EJ992_RS05805	COG1175	transmembrane transport
EJ992_RS05810	COG0395	ABC-type sugar transport system, permease component
EJ992_RS05815	COG1486	melibiose metabolic process
EJ992_RS05820	COG3180	Ammonia monooxygenase
EJ992_RS05835	COG3546	catalase activity
EJ992_RS05840	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS05845	COG2814	Major facilitator Superfamily
EJ992_RS05845	COG0477	Major facilitator Superfamily
EJ992_RS05855	COG5002	protein histidine kinase activity
EJ992_RS05860	COG0745	RESPONSE REGULATOR receiver
EJ992_RS05865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EJ992_RS05870	COG0725	ABC transporter, periplasmic molybdate-binding protein
EJ992_RS05875	COG4149	molybdate abc transporter
EJ992_RS05880	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EJ992_RS05885	COG1074	ATP-dependent DNA helicase activity
EJ992_RS05890	COG0420	3'-5' exonuclease activity
EJ992_RS05895	COG0419	ATPase involved in DNA repair
EJ992_RS05940	COG5337	Spore coat protein CotH
EJ992_RS05950	COG0179	Fumarylacetoacetate (FAA) hydrolase
EJ992_RS05970	COG0367	asparagine synthase
EJ992_RS05975	COG0004	ammonium transporteR
EJ992_RS05980	COG0347	Belongs to the P(II) protein family
EJ992_RS05985	COG0534	Mate efflux family protein
EJ992_RS05990	COG1917	Cupin 2, conserved barrel domain protein
EJ992_RS05990	COG2207	Transcriptional regulator
EJ992_RS06000	COG1609	Transcriptional regulator
EJ992_RS06005	COG0673	inositol 2-dehydrogenase activity
EJ992_RS06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EJ992_RS06020	COG0076	glutamate decarboxylase activity
EJ992_RS06045	COG2153	protein acetylation
EJ992_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS06055	COG2378	regulation of single-species biofilm formation
EJ992_RS06060	COG1410	methionine synthase
EJ992_RS06060	COG0646	methionine synthase
EJ992_RS06065	COG0646	methionine synthase
EJ992_RS06065	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EJ992_RS06070	COG1666	GTP binding
EJ992_RS06075	COG2996	Protein conserved in bacteria
EJ992_RS06090	COG1307	EDD domain protein, DegV family
EJ992_RS06095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS06105	COG0516	GMP reductase activity
EJ992_RS06115	COG0561	phosphatase activity
EJ992_RS06120	COG1073	alpha beta
EJ992_RS06125	COG2151	metal-sulfur cluster biosynthetic enzyme
EJ992_RS06135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EJ992_RS06140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EJ992_RS06145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EJ992_RS06150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EJ992_RS06155	COG0505	Belongs to the CarA family
EJ992_RS06160	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJ992_RS06165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJ992_RS06170	COG1968	undecaprenyl-diphosphatase activity
EJ992_RS06185	COG2267	carboxylic ester hydrolase activity
EJ992_RS06195	COG1744	ABC transporter substrate-binding protein PnrA-like
EJ992_RS06210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJ992_RS06215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EJ992_RS06220	COG5504	Zn-dependent protease
EJ992_RS06225	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS06230	COG4608	Belongs to the ABC transporter superfamily
EJ992_RS06240	COG0601	transmembrane transport
EJ992_RS06245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS06260	COG0180	Tryptophanyl-tRNA synthetase
EJ992_RS06270	COG4166	transmembrane transport
EJ992_RS06275	COG0601	transmembrane transport
EJ992_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS06285	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS06290	COG4608	Belongs to the ABC transporter superfamily
EJ992_RS06295	COG0456	acetyltransferase
EJ992_RS06300	COG1393	Belongs to the ArsC family
EJ992_RS06305	COG0861	Integral membrane protein TerC family
EJ992_RS06315	COG4862	establishment of competence for transformation
EJ992_RS06335	COG4565	transcriptional regulatory protein
EJ992_RS06340	COG3290	protein histidine kinase activity
EJ992_RS06345	COG4469	Competence protein
EJ992_RS06350	COG1164	Oligoendopeptidase f
EJ992_RS06355	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EJ992_RS06360	COG2346	COG2346, Truncated hemoglobins
EJ992_RS06365	COG0741	lytic transglycosylase activity
EJ992_RS06370	COG4116	CYTH
EJ992_RS06380	COG2357	RelA SpoT domain protein
EJ992_RS06385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJ992_RS06390	COG0564	pseudouridine synthase activity
EJ992_RS06395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EJ992_RS06405	COG0475	glutathione-regulated potassium exporter activity
EJ992_RS06405	COG0569	domain protein
EJ992_RS06410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EJ992_RS06415	COG0352	thiamine-phosphate diphosphorylase activity
EJ992_RS06425	COG2104	thiamine diphosphate biosynthetic process
EJ992_RS06430	COG2022	thiamine diphosphate biosynthetic process
EJ992_RS06435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EJ992_RS06440	COG0351	phosphomethylpyrimidine kinase
EJ992_RS06445	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EJ992_RS06500	COG0210	DNA helicase
EJ992_RS06510	COG0586	Pfam SNARE associated Golgi protein
EJ992_RS06515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJ992_RS06520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EJ992_RS06525	COG2246	polysaccharide biosynthetic process
EJ992_RS06530	COG2153	protein acetylation
EJ992_RS06535	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EJ992_RS06540	COG2382	esterase
EJ992_RS06560	COG0626	cystathionine gamma-synthase activity
EJ992_RS06565	COG0626	cystathionine gamma-synthase activity
EJ992_RS06570	COG5505	Protein of unknown function (DUF819)
EJ992_RS06585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJ992_RS06590	COG3507	Belongs to the glycosyl hydrolase 43 family
EJ992_RS06610	COG0110	maltose O-acetyltransferase activity
EJ992_RS06620	COG0583	DNA-binding transcription factor activity
EJ992_RS06625	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJ992_RS06630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EJ992_RS06640	COG0697	spore germination
EJ992_RS06645	COG0346	lactoylglutathione lyase activity
EJ992_RS06655	COG3584	3D domain protein
EJ992_RS06655	COG1388	LysM domain
EJ992_RS06660	COG2814	Major facilitator Superfamily
EJ992_RS06665	COG1309	transcriptional regulator
EJ992_RS06685	COG5444	nuclease activity
EJ992_RS06690	COG4195	phage-related replication protein
EJ992_RS06695	COG2856	Zn peptidase
EJ992_RS06700	COG1396	sequence-specific DNA binding
EJ992_RS06715	COG1522	sequence-specific DNA binding
EJ992_RS06720	COG1484	DNA-dependent DNA replication
EJ992_RS06735	COG1595	DNA-templated transcription, initiation
EJ992_RS06740	COG5484	DNA packaging
EJ992_RS06740	COG3728	DNA packaging
EJ992_RS06745	COG1783	phage Terminase large subunit
EJ992_RS06750	COG5518	Phage portal protein
EJ992_RS06755	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EJ992_RS06760	COG4653	Phage capsid family
EJ992_RS06810	COG3953	SLT domain
EJ992_RS06810	COG5412	phage tail tape measure protein
EJ992_RS06815	COG1652	LysM domain
EJ992_RS06820	COG4193	domain, Protein
EJ992_RS06830	COG3628	GPW Gp25 family protein
EJ992_RS06835	COG3299	homolog of phage Mu protein gp47
EJ992_RS06840	COG3778	Protein conserved in bacteria
EJ992_RS06875	COG1802	Transcriptional regulator
EJ992_RS06880	COG1063	alcohol dehydrogenase
EJ992_RS06885	COG1312	Catalyzes the dehydration of D-mannonate
EJ992_RS06890	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS06895	COG1063	alcohol dehydrogenase
EJ992_RS06900	COG2271	Major facilitator Superfamily
EJ992_RS06915	COG0306	phosphate transporter
EJ992_RS06920	COG1392	Phosphate transport regulator
EJ992_RS06925	COG0405	Gamma-glutamyltransferase
EJ992_RS06930	COG5578	integral membrane protein
EJ992_RS06935	COG2972	Histidine kinase
EJ992_RS06940	COG4753	response regulator
EJ992_RS06940	COG2207	Transcriptional regulator
EJ992_RS06945	COG1653	transport
EJ992_RS06950	COG1175	transmembrane transport
EJ992_RS06955	COG0395	ABC-type sugar transport system, permease component
EJ992_RS06960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EJ992_RS06965	COG2207	Transcriptional regulator
EJ992_RS06970	COG2755	lipolytic protein G-D-S-L family
EJ992_RS06980	COG5578	integral membrane protein
EJ992_RS06985	COG3401	FG-GAP repeat protein
EJ992_RS06995	COG2755	lipolytic protein G-D-S-L family
EJ992_RS07000	COG3401	FG-GAP repeat protein
EJ992_RS07005	COG0667	Aldo Keto reductase
EJ992_RS07010	COG2755	lipolytic protein G-D-S-L family
EJ992_RS07015	COG1874	Beta-galactosidase
EJ992_RS07025	COG1653	transport
EJ992_RS07030	COG4209	transmembrane transport
EJ992_RS07035	COG0395	ABC-type sugar transport system, permease component
EJ992_RS07040	COG0531	amino acid
EJ992_RS07045	COG0346	lactoylglutathione lyase activity
EJ992_RS07055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJ992_RS07060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJ992_RS07065	COG2362	D-Aminopeptidase
EJ992_RS07070	COG0601	transmembrane transport
EJ992_RS07075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS07080	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS07085	COG4166	transmembrane transport
EJ992_RS07090	COG1619	proteins homologs of microcin C7 resistance protein MccF
EJ992_RS07095	COG4948	Mandelate Racemase Muconate Lactonizing
EJ992_RS07100	COG0791	NLP P60 protein
EJ992_RS07105	COG4608	Belongs to the ABC transporter superfamily
EJ992_RS07110	COG1834	amidinotransferase
EJ992_RS07115	COG1607	acyl-coa hydrolase
EJ992_RS07120	COG2323	membrane
EJ992_RS07125	COG3866	Pectate lyase
EJ992_RS07145	COG2318	DinB family
EJ992_RS07150	COG2076	Multidrug Resistance protein
EJ992_RS07155	COG2076	Multidrug Resistance protein
EJ992_RS07160	COG0788	formyltetrahydrofolate deformylase activity
EJ992_RS07165	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EJ992_RS07170	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJ992_RS07175	COG1764	response to oxidative stress
EJ992_RS07180	COG1846	Transcriptional regulator
EJ992_RS07185	COG1764	response to oxidative stress
EJ992_RS07195	COG0590	tRNA wobble adenosine to inosine editing
EJ992_RS07200	COG0406	alpha-ribazole phosphatase activity
EJ992_RS07215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EJ992_RS07220	COG1404	Belongs to the peptidase S8 family
EJ992_RS07230	COG2239	Acts as a magnesium transporter
EJ992_RS07240	COG0582	viral genome integration into host DNA
EJ992_RS07245	COG2856	Zn peptidase
EJ992_RS07270	COG3620	sequence-specific DNA binding
EJ992_RS07315	COG5377	YqaJ viral recombinase family
EJ992_RS07320	COG3723	Recombinational DNA repair protein, rece pathway
EJ992_RS07325	COG3935	DnaD domain protein
EJ992_RS07330	COG1484	DNA-dependent DNA replication
EJ992_RS07365	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
EJ992_RS07380	COG0629	single-stranded DNA binding
EJ992_RS07405	COG3677	Transposase
EJ992_RS07415	COG5484	DNA packaging
EJ992_RS07420	COG1783	phage Terminase large subunit
EJ992_RS07540	COG0662	Cupin 2, conserved barrel domain protein
EJ992_RS07545	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EJ992_RS07550	COG2323	membrane
EJ992_RS07555	COG0789	Transcriptional regulator
EJ992_RS07570	COG1846	Transcriptional regulator
EJ992_RS07575	COG1793	dna ligase
EJ992_RS07575	COG3285	dna ligase
EJ992_RS07580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EJ992_RS07585	COG5001	Diguanylate cyclase
EJ992_RS07585	COG3300	MHYT domain
EJ992_RS07590	COG0586	Pfam SNARE associated Golgi protein
EJ992_RS07595	COG0861	Integral membrane protein TerC family
EJ992_RS07600	COG1191	sigma factor activity
EJ992_RS07620	COG0501	Belongs to the peptidase M48B family
EJ992_RS07625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EJ992_RS07630	COG0768	penicillin binding
EJ992_RS07645	COG3594	Acyltransferase
EJ992_RS07650	COG5002	protein histidine kinase activity
EJ992_RS07655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EJ992_RS07660	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EJ992_RS07665	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EJ992_RS07670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EJ992_RS07675	COG0436	Aminotransferase
EJ992_RS07680	COG1850	ribulose-bisphosphate carboxylase activity
EJ992_RS07685	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EJ992_RS07685	COG0235	Class ii aldolase
EJ992_RS07690	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EJ992_RS07695	COG0346	lactoylglutathione lyase activity
EJ992_RS07700	COG3339	Conserved Protein
EJ992_RS07710	COG3852	Histidine kinase
EJ992_RS07715	COG1846	Transcriptional regulator
EJ992_RS07720	COG1360	Flagellar Motor Protein
EJ992_RS07725	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EJ992_RS07730	COG0542	response to heat
EJ992_RS07735	COG3949	Membrane
EJ992_RS07740	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EJ992_RS07745	COG0720	synthase
EJ992_RS07750	COG0602	queuosine metabolic process
EJ992_RS07755	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EJ992_RS07765	COG4974	Belongs to the 'phage' integrase family
EJ992_RS07770	COG4974	Belongs to the 'phage' integrase family
EJ992_RS07800	COG1793	dna ligase
EJ992_RS07880	COG0740	serine-type endopeptidase activity
EJ992_RS07930	COG3953	SLT domain
EJ992_RS07930	COG5280	Phage tail tape measure protein TP901
EJ992_RS07965	COG0584	glycerophosphoryl diester phosphodiesterase
EJ992_RS07975	COG3409	Peptidoglycan-binding domain 1 protein
EJ992_RS07975	COG1388	LysM domain
EJ992_RS07975	COG5632	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS08005	COG0582	viral genome integration into host DNA
EJ992_RS08020	COG3739	integral membrane protein
EJ992_RS08025	COG3655	Transcriptional regulator
EJ992_RS08055	COG4873	Protein conserved in bacteria
EJ992_RS08065	COG3773	Cell wall hydrolase
EJ992_RS08070	COG2244	polysaccharide biosynthetic process
EJ992_RS08075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS08080	COG2217	Heavy metal translocating P-type atpase
EJ992_RS08085	COG0006	proline dipeptidase activity
EJ992_RS08095	COG1609	Transcriptional regulator
EJ992_RS08100	COG3711	transcriptional antiterminator
EJ992_RS08105	COG2190	(PTS) system
EJ992_RS08105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS08105	COG1263	PTS System
EJ992_RS08110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS08115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EJ992_RS08125	COG1533	DNA photolyase activity
EJ992_RS08130	COG0456	acetyltransferase
EJ992_RS08135	COG0840	transmembrane signaling receptor activity
EJ992_RS08140	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS08145	COG2084	Dehydrogenase
EJ992_RS08150	COG2340	Cysteine-rich secretory protein family
EJ992_RS08155	COG0768	penicillin binding
EJ992_RS08160	COG4191	Histidine kinase
EJ992_RS08165	COG0436	Aminotransferase
EJ992_RS08170	COG1714	RDD family
EJ992_RS08180	COG0784	Response regulator, receiver
EJ992_RS08180	COG0835	chemotaxis
EJ992_RS08190	COG2814	Major facilitator Superfamily
EJ992_RS08195	COG1376	ErfK ybiS ycfS ynhG family protein
EJ992_RS08205	COG1408	metallophosphoesterase
EJ992_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS08215	COG2200	EAL domain
EJ992_RS08225	COG4703	Protein of unknown function (DUF1797)
EJ992_RS08230	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EJ992_RS08240	COG0517	IMP dehydrogenase activity
EJ992_RS08245	COG0583	DNA-binding transcription factor activity
EJ992_RS08250	COG0716	FMN binding
EJ992_RS08260	COG0716	FMN binding
EJ992_RS08265	COG2171	N-acyltransferase activity
EJ992_RS08270	COG1473	amidohydrolase
EJ992_RS08280	COG0450	alkyl hydroperoxide reductase
EJ992_RS08285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS08300	COG0746	molybdenum cofactor guanylyltransferase activity
EJ992_RS08305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EJ992_RS08310	COG0303	'Molybdopterin
EJ992_RS08315	COG1763	Mo-molybdopterin cofactor biosynthetic process
EJ992_RS08320	COG0314	molybdopterin synthase activity
EJ992_RS08325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EJ992_RS08335	COG1132	(ABC) transporter
EJ992_RS08340	COG1132	(ABC) transporter
EJ992_RS08350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EJ992_RS08355	COG1136	(ABC) transporter
EJ992_RS08360	COG0577	efflux transmembrane transporter activity
EJ992_RS08365	COG1349	DNA-binding transcription factor activity
EJ992_RS08370	COG1105	Belongs to the carbohydrate kinase PfkB family
EJ992_RS08375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS08375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS08375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS08395	COG0488	(ABC) transporter
EJ992_RS08405	COG2309	aminopeptidase activity
EJ992_RS08415	COG1077	Cell shape determining protein MreB Mrl
EJ992_RS08420	COG2002	toxin-antitoxin pair type II binding
EJ992_RS08425	COG3852	Histidine kinase
EJ992_RS08430	COG0569	domain protein
EJ992_RS08435	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EJ992_RS08440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EJ992_RS08445	COG5503	Protein of unknown function (DUF1447)
EJ992_RS08450	COG0561	phosphatase activity
EJ992_RS08455	COG0242	peptide deformylase activity
EJ992_RS08465	COG0497	DNA recombination
EJ992_RS08470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJ992_RS08475	COG0022	dehydrogenase e1 component
EJ992_RS08480	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJ992_RS08485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJ992_RS08495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS08505	COG1982	Orn Lys Arg decarboxylase major
EJ992_RS08515	COG4476	Belongs to the UPF0223 family
EJ992_RS08520	COG4493	Belongs to the UPF0637 family
EJ992_RS08530	COG0483	inositol monophosphate 1-phosphatase activity
EJ992_RS08550	COG1595	DNA-templated transcription, initiation
EJ992_RS08565	COG1217	gtp-binding protein TYPA
EJ992_RS08575	COG1846	Transcriptional regulator
EJ992_RS08580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EJ992_RS08585	COG4896	Protein conserved in bacteria
EJ992_RS08595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EJ992_RS08600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJ992_RS08605	COG2066	Belongs to the glutaminase family
EJ992_RS08610	COG4838	Belongs to the UPF0358 family
EJ992_RS08615	COG0772	Belongs to the SEDS family
EJ992_RS08620	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EJ992_RS08625	COG1612	heme a metabolic process
EJ992_RS08630	COG0109	protoheme IX farnesyltransferase activity
EJ992_RS08635	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EJ992_RS08635	COG2010	Cytochrome c
EJ992_RS08640	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJ992_RS08645	COG1845	cytochrome c oxidase, subunit III
EJ992_RS08650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EJ992_RS08655	COG3336	cytochrome c oxidase
EJ992_RS08665	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EJ992_RS08670	COG2340	Cysteine-rich secretory protein family
EJ992_RS08685	COG3679	Belongs to the UPF0342 family
EJ992_RS08690	COG4471	UPF0298 protein
EJ992_RS08695	COG0742	ribosomal rna small subunit methyltransferase
EJ992_RS08700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EJ992_RS08705	COG3314	Sporulation integral membrane protein YlbJ
EJ992_RS08710	COG3480	Lon protease (S16) C-terminal proteolytic domain
EJ992_RS08715	COG1323	Belongs to the UPF0348 family
EJ992_RS08720	COG1399	metal-binding, possibly nucleic acid-binding protein
EJ992_RS08725	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EJ992_RS08735	COG0454	-acetyltransferase
EJ992_RS08740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EJ992_RS08745	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EJ992_RS08750	COG2001	Belongs to the MraZ family
EJ992_RS08755	COG0275	rRNA processing
EJ992_RS08760	COG4839	cell division protein FtsL
EJ992_RS08765	COG0768	penicillin binding
EJ992_RS08770	COG0768	penicillin binding
EJ992_RS08775	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EJ992_RS08780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJ992_RS08785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EJ992_RS08790	COG0772	Belongs to the SEDS family
EJ992_RS08795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJ992_RS08800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EJ992_RS08805	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EJ992_RS08810	COG3879	Bacterial protein of unknown function (DUF881)
EJ992_RS08815	COG3879	Bacterial protein of unknown function (DUF881)
EJ992_RS08820	COG3856	small basic protein
EJ992_RS08825	COG0849	cell division
EJ992_RS08830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EJ992_RS08840	COG1404	Belongs to the peptidase S8 family
EJ992_RS08840	COG4412	M6 family metalloprotease domain protein
EJ992_RS08845	COG1404	Belongs to the peptidase S8 family
EJ992_RS08845	COG4412	M6 family metalloprotease domain protein
EJ992_RS08855	COG1191	sigma factor activity
EJ992_RS08860	COG1191	sigma factor activity
EJ992_RS08865	COG1119	ATPase activity
EJ992_RS08870	COG2226	methyltransferase
EJ992_RS08875	COG0500	methyltransferase
EJ992_RS08880	COG1873	PFAM PRC-barrel domain
EJ992_RS08885	COG1496	oxidoreductase activity
EJ992_RS08890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EJ992_RS08895	COG1799	cell septum assembly
EJ992_RS08900	COG0762	integral membrane protein
EJ992_RS08905	COG2302	S4 RNA-binding domain
EJ992_RS08910	COG3599	regulation of cell shape
EJ992_RS08915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EJ992_RS08920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EJ992_RS08925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EJ992_RS08930	COG0564	pseudouridine synthase activity
EJ992_RS08935	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EJ992_RS08940	COG2233	PERMEase
EJ992_RS08945	COG0540	Belongs to the ATCase OTCase family
EJ992_RS08950	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EJ992_RS08955	COG0505	Belongs to the CarA family
EJ992_RS08960	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EJ992_RS08965	COG0543	2 iron, 2 sulfur cluster binding
EJ992_RS08970	COG0167	dihydroorotate dehydrogenase activity
EJ992_RS08975	COG0284	orotidine-5'-phosphate decarboxylase activity
EJ992_RS08980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EJ992_RS08990	COG0175	sulfate reduction
EJ992_RS08995	COG0306	phosphate transporter
EJ992_RS09000	COG2046	Belongs to the sulfate adenylyltransferase family
EJ992_RS09005	COG0529	Catalyzes the synthesis of activated sulfate
EJ992_RS09010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EJ992_RS09015	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EJ992_RS09020	COG1648	precorrin-2 dehydrogenase activity
EJ992_RS09030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EJ992_RS09035	COG1561	YicC-like family, N-terminal region
EJ992_RS09040	COG2052	Domain of unknown function (DUF370)
EJ992_RS09045	COG0194	GDP metabolic process
EJ992_RS09050	COG1758	RNA polymerase activity
EJ992_RS09055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EJ992_RS09060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EJ992_RS09065	COG0242	peptide deformylase activity
EJ992_RS09070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EJ992_RS09075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJ992_RS09075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EJ992_RS09080	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EJ992_RS09085	COG0631	protein serine/threonine phosphatase activity
EJ992_RS09090	COG0515	serine threonine protein kinase
EJ992_RS09090	COG2815	serine threonine protein kinase
EJ992_RS09095	COG1162	GTPase activity
EJ992_RS09100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EJ992_RS09105	COG1564	THIamine pyrophosphokinase
EJ992_RS09115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EJ992_RS09120	COG1302	Protein conserved in bacteria
EJ992_RS09125	COG1461	Dihydroxyacetone kinase
EJ992_RS09130	COG1760	l-serine dehydratase
EJ992_RS09135	COG1760	l-serine dehydratase
EJ992_RS09140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EJ992_RS09145	COG1349	DNA-binding transcription factor activity
EJ992_RS09150	COG0416	fatty acid biosynthetic process
EJ992_RS09155	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EJ992_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJ992_RS09170	COG0571	ribonuclease III activity
EJ992_RS09175	COG1196	nuclear chromosome segregation
EJ992_RS09180	COG0552	protein localization to endoplasmic reticulum
EJ992_RS09185	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EJ992_RS09190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EJ992_RS09195	COG0228	four-way junction DNA binding
EJ992_RS09200	COG1837	Belongs to the UPF0109 family
EJ992_RS09210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EJ992_RS09215	COG0336	Belongs to the RNA methyltransferase TrmD family
EJ992_RS09220	COG0335	large ribosomal subunit rRNA binding
EJ992_RS09225	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EJ992_RS09230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJ992_RS09240	COG2257	FlhB HrpN YscU SpaS Family
EJ992_RS09245	COG0045	succinate-CoA ligase (ADP-forming) activity
EJ992_RS09250	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EJ992_RS09255	COG0758	DNA mediated transformation
EJ992_RS09260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EJ992_RS09265	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EJ992_RS09270	COG4974	Belongs to the 'phage' integrase family
EJ992_RS09275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EJ992_RS09280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EJ992_RS09285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EJ992_RS09290	COG1815	bacterial-type flagellum-dependent cell motility
EJ992_RS09295	COG1558	bacterial-type flagellum-dependent cell motility
EJ992_RS09300	COG1677	Flagellar hook-basal body complex protein FliE
EJ992_RS09305	COG1766	The M ring may be actively involved in energy transduction
EJ992_RS09310	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EJ992_RS09315	COG1317	bacterial-type flagellum organization
EJ992_RS09320	COG1157	protein secretion by the type III secretion system
EJ992_RS09325	COG2882	bacterial-type flagellum organization
EJ992_RS09335	COG3144	bacterial-type flagellum assembly
EJ992_RS09340	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EJ992_RS09345	COG4786	Flagellar basal body rod
EJ992_RS09350	COG1582	Flagellar protein (FlbD)
EJ992_RS09355	COG1580	Controls the rotational direction of flagella during chemotaxis
EJ992_RS09360	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EJ992_RS09365	COG1776	CheC inhibitor of MCP methylation
EJ992_RS09365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EJ992_RS09370	COG2201	protein-glutamate methylesterase activity
EJ992_RS09375	COG3190	flagellar
EJ992_RS09380	COG1338	Plays a role in the flagellum-specific transport system
EJ992_RS09385	COG1987	bacterial-type flagellum assembly
EJ992_RS09390	COG1684	flagellar biosynthetic protein fliR
EJ992_RS09395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EJ992_RS09400	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EJ992_RS09405	COG1419	protein localization to endoplasmic reticulum
EJ992_RS09410	COG0455	bacterial-type flagellum organization
EJ992_RS09415	COG2201	protein-glutamate methylesterase activity
EJ992_RS09420	COG2198	Histidine kinase
EJ992_RS09420	COG0643	Histidine kinase
EJ992_RS09425	COG0835	chemotaxis
EJ992_RS09430	COG1776	CheC inhibitor of MCP methylation
EJ992_RS09435	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EJ992_RS09440	COG1191	sigma factor activity
EJ992_RS09450	COG0052	Belongs to the universal ribosomal protein uS2 family
EJ992_RS09455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EJ992_RS09460	COG0528	UMP kinase activity
EJ992_RS09465	COG0233	cytoplasmic translational termination
EJ992_RS09470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EJ992_RS09475	COG4589	Belongs to the CDS family
EJ992_RS09480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EJ992_RS09485	COG0750	zinc metalloprotease
EJ992_RS09490	COG0442	prolyl-tRNA aminoacylation
EJ992_RS09495	COG2176	DNA-directed DNA polymerase activity
EJ992_RS09525	COG0779	Required for maturation of 30S ribosomal subunits
EJ992_RS09530	COG0195	Participates in both transcription termination and antitermination
EJ992_RS09535	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EJ992_RS09540	COG1358	cellular component organization or biogenesis
EJ992_RS09545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EJ992_RS09550	COG1550	Protein conserved in bacteria
EJ992_RS09555	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EJ992_RS09560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EJ992_RS09565	COG0196	riboflavin kinase activity
EJ992_RS09570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EJ992_RS09575	COG1185	polyribonucleotide nucleotidyltransferase activity
EJ992_RS09580	COG0726	polysaccharide deacetylase
EJ992_RS09585	COG0612	Peptidase, M16
EJ992_RS09590	COG1873	PFAM PRC-barrel domain
EJ992_RS09595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJ992_RS09600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EJ992_RS09605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EJ992_RS09610	COG0527	aspartate kinase activity
EJ992_RS09620	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EJ992_RS09625	COG0740	serine-type endopeptidase activity
EJ992_RS09635	COG4980	gas vesicle protein
EJ992_RS09635	COG1674	ftsk spoiiie
EJ992_RS09640	COG2188	Transcriptional regulator
EJ992_RS09645	COG2814	Major facilitator Superfamily
EJ992_RS09650	COG0612	Peptidase, M16
EJ992_RS09655	COG0612	Peptidase, M16
EJ992_RS09660	COG0300	oxidoreductase activity
EJ992_RS09675	COG1426	Protein conserved in bacteria
EJ992_RS09680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EJ992_RS09685	COG1546	Belongs to the CinA family
EJ992_RS09685	COG1058	Belongs to the CinA family
EJ992_RS09695	COG1418	mRNA catabolic process
EJ992_RS09700	COG1692	metallophosphoesterase
EJ992_RS09705	COG2359	stage V sporulation protein S
EJ992_RS09715	COG1063	alcohol dehydrogenase
EJ992_RS09720	COG0156	8-amino-7-oxononanoate synthase activity
EJ992_RS09725	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJ992_RS09730	COG4550	Control of competence regulator ComK, YlbF/YmcA
EJ992_RS09740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EJ992_RS09745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EJ992_RS09750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EJ992_RS09755	COG5444	nuclease activity
EJ992_RS09775	COG0523	cobalamin synthesis protein
EJ992_RS09785	COG1247	-acetyltransferase
EJ992_RS09805	COG3619	membrane
EJ992_RS09810	COG3263	regulation of cellular component size
EJ992_RS09830	COG0393	Putative heavy-metal-binding
EJ992_RS09835	COG0398	Pfam SNARE associated Golgi protein
EJ992_RS09840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EJ992_RS09845	COG1819	glycosyl
EJ992_RS09850	COG0531	amino acid
EJ992_RS09855	COG5577	PFAM Coat F domain
EJ992_RS09865	COG3858	chitin binding
EJ992_RS09865	COG1388	LysM domain
EJ992_RS09870	COG1309	transcriptional regulator
EJ992_RS09875	COG3631	Ketosteroid isomerase-related protein
EJ992_RS09880	COG0702	epimerase
EJ992_RS09890	COG1764	response to oxidative stress
EJ992_RS09895	COG2076	Multidrug Resistance protein
EJ992_RS09900	COG2076	Multidrug Resistance protein
EJ992_RS09915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EJ992_RS09920	COG1923	regulation of RNA biosynthetic process
EJ992_RS09935	COG1780	Probably involved in ribonucleotide reductase function
EJ992_RS09940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJ992_RS09945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EJ992_RS09950	COG4112	unkown
EJ992_RS09965	COG0735	belongs to the Fur family
EJ992_RS09970	COG1802	Transcriptional regulator
EJ992_RS09975	COG0697	spore germination
EJ992_RS10010	COG1309	transcriptional regulator
EJ992_RS10060	COG0464	growth
EJ992_RS10065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EJ992_RS10070	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EJ992_RS10075	COG0789	Transcriptional regulator
EJ992_RS10080	COG0174	glutamine synthetase
EJ992_RS10120	COG1073	alpha beta
EJ992_RS10160	COG1309	transcriptional regulator
EJ992_RS10165	COG2076	Multidrug Resistance protein
EJ992_RS10170	COG2076	Multidrug Resistance protein
EJ992_RS10175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS10195	COG3546	catalase activity
EJ992_RS10220	COG1846	Transcriptional regulator
EJ992_RS10225	COG0778	Nitroreductase
EJ992_RS10230	COG0346	lactoylglutathione lyase activity
EJ992_RS10235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EJ992_RS10240	COG0655	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS10260	COG3209	COG3209 Rhs family protein
EJ992_RS10265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJ992_RS10270	COG1388	LysM domain
EJ992_RS10275	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EJ992_RS10280	COG4224	UPF0291 protein
EJ992_RS10285	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EJ992_RS10295	COG3763	UPF0154 protein
EJ992_RS10305	COG0785	Cytochrome C biogenesis protein
EJ992_RS10310	COG2201	protein-glutamate methylesterase activity
EJ992_RS10315	COG4846	Membrane protein involved in cytochrome C biogenesis
EJ992_RS10325	COG0071	Belongs to the small heat shock protein (HSP20) family
EJ992_RS10340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EJ992_RS10345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS10365	COG0824	Thioesterase
EJ992_RS10390	COG4841	protein insertion into membrane
EJ992_RS10395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EJ992_RS10400	COG1832	CoA-binding protein
EJ992_RS10405	COG0187	DNA topoisomerase II activity
EJ992_RS10410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EJ992_RS10415	COG1609	Transcriptional regulator
EJ992_RS10430	COG2160	L-arabinose isomerase activity
EJ992_RS10450	COG1115	amino acid carrier protein
EJ992_RS10460	COG2181	nitrate reductase activity
EJ992_RS10465	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EJ992_RS10470	COG1140	nitrate reductase beta subunit
EJ992_RS10475	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EJ992_RS10490	COG0535	radical SAM domain protein
EJ992_RS10495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJ992_RS10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EJ992_RS10510	COG2223	nitrite transmembrane transporter activity
EJ992_RS10530	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EJ992_RS10540	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EJ992_RS10550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS10560	COG0492	ferredoxin-NADP+ reductase activity
EJ992_RS10575	COG3420	alginic acid biosynthetic process
EJ992_RS10580	COG1114	Component of the transport system for branched-chain amino acids
EJ992_RS10585	COG1064	alcohol dehydrogenase
EJ992_RS10590	COG0789	Transcriptional regulator
EJ992_RS10615	COG1024	Enoyl-CoA hydratase
EJ992_RS10620	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS10625	COG2084	Dehydrogenase
EJ992_RS10630	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS10635	COG1482	cell wall glycoprotein biosynthetic process
EJ992_RS10640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS10640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS10640	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS10665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS10665	COG3711	transcriptional antiterminator
EJ992_RS10680	COG1725	Transcriptional regulator
EJ992_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS10690	COG1312	Catalyzes the dehydration of D-mannonate
EJ992_RS10705	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EJ992_RS10715	COG1609	Transcriptional regulator
EJ992_RS10720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJ992_RS10725	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EJ992_RS10730	COG0640	Transcriptional regulator
EJ992_RS10740	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EJ992_RS10755	COG1649	PFAM Uncharacterised BCR, COG1649
EJ992_RS10760	COG2404	hydrolase activity, acting on ester bonds
EJ992_RS10765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EJ992_RS10775	COG2027	D-alanyl-D-alanine carboxypeptidase
EJ992_RS10780	COG1252	NADH dehydrogenase
EJ992_RS10795	COG0166	Belongs to the GPI family
EJ992_RS10805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJ992_RS10810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJ992_RS10815	COG1024	Enoyl-CoA hydratase
EJ992_RS10820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJ992_RS10825	COG0511	ligase activity, forming carbon-carbon bonds
EJ992_RS10830	COG0439	Biotin carboxylase
EJ992_RS10835	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS10840	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS10845	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS10850	COG1733	regulation of RNA biosynthetic process
EJ992_RS10855	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EJ992_RS10860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EJ992_RS10870	COG2323	membrane
EJ992_RS10880	COG0306	phosphate transporter
EJ992_RS10885	COG0175	sulfate reduction
EJ992_RS10890	COG1809	phosphosulfolactate synthase activity
EJ992_RS10895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS10900	COG4948	Mandelate Racemase Muconate Lactonizing
EJ992_RS10905	COG2814	Major facilitator Superfamily
EJ992_RS10910	COG0463	Glycosyl transferase, family 2
EJ992_RS10925	COG0493	'glutamate synthase
EJ992_RS10930	COG0070	glutamate synthase
EJ992_RS10930	COG0069	glutamate synthase activity
EJ992_RS10930	COG0067	glutamate synthase
EJ992_RS10935	COG0583	DNA-binding transcription factor activity
EJ992_RS10955	COG1846	Transcriptional regulator
EJ992_RS10965	COG1132	(ABC) transporter
EJ992_RS10975	COG0300	oxidoreductase activity
EJ992_RS10980	COG3848	Pyruvate phosphate dikinase
EJ992_RS10980	COG0574	Belongs to the PEP-utilizing enzyme family
EJ992_RS10990	COG0477	Major facilitator Superfamily
EJ992_RS10995	COG0243	molybdopterin cofactor binding
EJ992_RS11000	COG1846	Transcriptional regulator
EJ992_RS11010	COG0531	amino acid
EJ992_RS11020	COG0531	amino acid
EJ992_RS11025	COG0531	amino acid
EJ992_RS11030	COG0697	spore germination
EJ992_RS11035	COG0488	(ABC) transporter
EJ992_RS11040	COG0840	transmembrane signaling receptor activity
EJ992_RS11045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJ992_RS11050	COG1404	Belongs to the peptidase S8 family
EJ992_RS11060	COG1309	transcriptional regulator
EJ992_RS11065	COG1846	Transcriptional regulator
EJ992_RS11095	COG1309	transcriptional regulator
EJ992_RS11100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS11105	COG3708	Transcriptional regulator
EJ992_RS11115	COG2378	regulation of single-species biofilm formation
EJ992_RS11125	COG0640	Transcriptional regulator
EJ992_RS11130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS11140	COG0531	amino acid
EJ992_RS11145	COG0741	lytic transglycosylase activity
EJ992_RS11150	COG1086	Polysaccharide biosynthesis protein
EJ992_RS11170	COG2322	membrane
EJ992_RS11185	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS11190	COG1388	LysM domain
EJ992_RS11190	COG3584	3D domain protein
EJ992_RS11195	COG0514	ATP-dependent DNA helicase (RecQ)
EJ992_RS11215	COG2315	Protein conserved in bacteria
EJ992_RS11235	COG2427	Protein of unknown function (DUF1641)
EJ992_RS11240	COG3383	formate dehydrogenase (NAD+) activity
EJ992_RS11260	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EJ992_RS11305	COG0402	S-adenosylhomocysteine deaminase activity
EJ992_RS11320	COG2267	carboxylic ester hydrolase activity
EJ992_RS11335	COG1280	lysine exporter protein (LysE YggA)
EJ992_RS11340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EJ992_RS11350	COG0574	Belongs to the PEP-utilizing enzyme family
EJ992_RS11350	COG3848	Pyruvate phosphate dikinase
EJ992_RS11355	COG1309	transcriptional regulator
EJ992_RS11370	COG2318	DinB family
EJ992_RS11375	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EJ992_RS11380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EJ992_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS11400	COG2814	Major facilitator Superfamily
EJ992_RS11415	COG1657	PFAM Prenyltransferase squalene oxidase
EJ992_RS11420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJ992_RS11430	COG0733	neurotransmitter:sodium symporter activity
EJ992_RS11435	COG0385	Bile acid
EJ992_RS11440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJ992_RS11445	COG0567	Dehydrogenase, E1 component
EJ992_RS11450	COG4548	von Willebrand factor, type A
EJ992_RS11455	COG0714	Associated with various cellular activities
EJ992_RS11460	COG2032	superoxide dismutase activity
EJ992_RS11465	COG0791	NLP P60 protein
EJ992_RS11465	COG1388	LysM domain
EJ992_RS11475	COG0534	Mate efflux family protein
EJ992_RS11480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJ992_RS11485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJ992_RS11495	COG2962	Rard protein
EJ992_RS11505	COG4305	rare lipoprotein A
EJ992_RS11515	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS11520	COG1733	regulation of RNA biosynthetic process
EJ992_RS11525	COG0778	Nitroreductase
EJ992_RS11530	COG0400	carboxylic ester hydrolase activity
EJ992_RS11540	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS11550	COG3409	Peptidoglycan-binding domain 1 protein
EJ992_RS11550	COG0793	Belongs to the peptidase S41A family
EJ992_RS11555	COG2226	methyltransferase
EJ992_RS11565	COG1876	peptidase activity
EJ992_RS11570	COG0813	purine-nucleoside phosphorylase activity
EJ992_RS11575	COG0701	Predicted permease
EJ992_RS11595	COG0671	phosphoesterase, PA-phosphatase related
EJ992_RS11610	COG4479	Belongs to the UPF0346 family
EJ992_RS11620	COG1509	lysine 2,3-aminomutase activity
EJ992_RS11625	COG0456	acetyltransferase
EJ992_RS11630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJ992_RS11635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EJ992_RS11640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EJ992_RS11645	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EJ992_RS11660	COG0456	acetyltransferase
EJ992_RS11665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJ992_RS11670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EJ992_RS11675	COG1846	Transcriptional regulator
EJ992_RS11685	COG3706	GGDEF domain
EJ992_RS11690	COG0534	Mate efflux family protein
EJ992_RS11705	COG4698	Protein conserved in bacteria
EJ992_RS11710	COG2755	lipolytic protein G-D-S-L family
EJ992_RS11715	COG1999	signal sequence binding
EJ992_RS11730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EJ992_RS11735	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EJ992_RS11740	COG1272	protein, Hemolysin III
EJ992_RS11745	COG0204	Acyl-transferase
EJ992_RS11750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EJ992_RS11755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EJ992_RS11765	COG2136	Putative SAM-dependent methyltransferase
EJ992_RS11765	COG2521	methyltransferase
EJ992_RS11775	COG0129	dihydroxy-acid dehydratase activity
EJ992_RS11780	COG1413	lyase activity
EJ992_RS11785	COG1418	mRNA catabolic process
EJ992_RS11790	COG0386	Belongs to the glutathione peroxidase family
EJ992_RS11795	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EJ992_RS11800	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EJ992_RS11805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJ992_RS11815	COG1278	Cold shock
EJ992_RS11835	COG0328	RNA-DNA hybrid ribonuclease activity
EJ992_RS11840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EJ992_RS11845	COG0328	RNA-DNA hybrid ribonuclease activity
EJ992_RS11855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJ992_RS11865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EJ992_RS11875	COG1755	Isoprenylcysteine carboxyl methyltransferase
EJ992_RS11880	COG3424	synthase
EJ992_RS11885	COG0456	acetyltransferase
EJ992_RS11890	COG2233	PERMEase
EJ992_RS11895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJ992_RS11900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EJ992_RS11905	COG1199	ATP-dependent helicase activity
EJ992_RS11915	COG0116	Belongs to the methyltransferase superfamily
EJ992_RS11925	COG3599	regulation of cell shape
EJ992_RS11930	COG4474	Belongs to the UPF0398 family
EJ992_RS11940	COG3359	exonuclease
EJ992_RS11945	COG1205	dead DEAH box helicase
EJ992_RS11945	COG1111	helicase
EJ992_RS11950	COG2190	(PTS) system
EJ992_RS11955	COG0071	Belongs to the small heat shock protein (HSP20) family
EJ992_RS11990	COG3331	DNA recombination
EJ992_RS11995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJ992_RS11995	COG4499	WXG100 protein secretion system (Wss), protein YukC
EJ992_RS12005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EJ992_RS12010	COG3935	DnaD domain protein
EJ992_RS12015	COG0017	Asparaginyl-tRNA synthetase
EJ992_RS12020	COG0436	Aminotransferase
EJ992_RS12025	COG5353	protein conserved in bacteria
EJ992_RS12035	COG1199	ATP-dependent helicase activity
EJ992_RS12035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EJ992_RS12040	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EJ992_RS12045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EJ992_RS12050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EJ992_RS12065	COG0617	tRNA 3'-terminal CCA addition
EJ992_RS12070	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS12075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EJ992_RS12080	COG1803	Methylglyoxal synthase
EJ992_RS12085	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EJ992_RS12090	COG1694	Mazg nucleotide pyrophosphohydrolase
EJ992_RS12095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS12105	COG4347	Protein of unknown function (DUF1405)
EJ992_RS12110	COG2010	Cytochrome c
EJ992_RS12110	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJ992_RS12115	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EJ992_RS12120	COG0723	plastoquinol--plastocyanin reductase activity
EJ992_RS12130	COG5582	Belongs to the UPF0302 family
EJ992_RS12135	COG0457	Tetratricopeptide repeat
EJ992_RS12140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EJ992_RS12145	COG0287	Prephenate dehydrogenase
EJ992_RS12150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EJ992_RS12155	COG0159	tryptophan synthase activity
EJ992_RS12160	COG0133	tryptophan synthase activity
EJ992_RS12165	COG0135	phosphoribosylanthranilate isomerase activity
EJ992_RS12170	COG0134	indole-3-glycerol-phosphate synthase activity
EJ992_RS12175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJ992_RS12180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EJ992_RS12185	COG4401	Chorismate mutase type I
EJ992_RS12190	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EJ992_RS12195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EJ992_RS12200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EJ992_RS12205	COG0105	UTP biosynthetic process
EJ992_RS12210	COG0142	geranyltranstransferase activity
EJ992_RS12215	COG2226	methyltransferase
EJ992_RS12220	COG0142	geranyltranstransferase activity
EJ992_RS12235	COG0776	regulation of translation
EJ992_RS12240	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EJ992_RS12260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EJ992_RS12265	COG1160	GTP binding
EJ992_RS12290	COG1304	FMN binding
EJ992_RS12295	COG0539	negative regulation of cytoplasmic translation
EJ992_RS12300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EJ992_RS12305	COG2959	enzyme of heme biosynthesis
EJ992_RS12310	COG3773	Cell wall hydrolase
EJ992_RS12310	COG3409	Peptidoglycan-binding domain 1 protein
EJ992_RS12315	COG2339	peptidase activity
EJ992_RS12325	COG0492	ferredoxin-NADP+ reductase activity
EJ992_RS12330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EJ992_RS12335	COG4862	establishment of competence for transformation
EJ992_RS12340	COG1408	metallophosphoesterase
EJ992_RS12350	COG1388	LysM domain
EJ992_RS12355	COG1266	CAAX protease self-immunity
EJ992_RS12360	COG0514	ATP-dependent DNA helicase (RecQ)
EJ992_RS12365	COG4955	Helix-turn-helix domain
EJ992_RS12370	COG1141	Ferredoxin
EJ992_RS12375	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EJ992_RS12380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EJ992_RS12395	COG1595	DNA-templated transcription, initiation
EJ992_RS12400	COG1316	TRANSCRIPTIONal
EJ992_RS12415	COG5002	protein histidine kinase activity
EJ992_RS12420	COG0745	RESPONSE REGULATOR receiver
EJ992_RS12425	COG5002	protein histidine kinase activity
EJ992_RS12430	COG0745	RESPONSE REGULATOR receiver
EJ992_RS12435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJ992_RS12440	COG1333	cytochrome c biogenesis protein
EJ992_RS12445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS12450	COG1187	pseudouridine synthase activity
EJ992_RS12455	COG0700	Nucleoside recognition
EJ992_RS12460	COG2715	membrane protein required for spore maturation
EJ992_RS12465	COG1686	Belongs to the peptidase S11 family
EJ992_RS12475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EJ992_RS12480	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EJ992_RS12490	COG1547	Domain of unknown function (DUF309)
EJ992_RS12495	COG0456	acetyltransferase
EJ992_RS12500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EJ992_RS12505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJ992_RS12505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EJ992_RS12510	COG0307	riboflavin synthase, alpha
EJ992_RS12515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJ992_RS12515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EJ992_RS12540	COG0457	Tetratricopeptide repeat
EJ992_RS12545	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EJ992_RS12550	COG4086	secreted protein
EJ992_RS12560	COG4195	phage-related replication protein
EJ992_RS12565	COG0019	diaminopimelate decarboxylase activity
EJ992_RS12575	COG0697	spore germination
EJ992_RS12590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EJ992_RS12615	COG2172	sigma factor antagonist activity
EJ992_RS12625	COG1686	Belongs to the peptidase S11 family
EJ992_RS12630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EJ992_RS12635	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EJ992_RS12640	COG4974	Belongs to the 'phage' integrase family
EJ992_RS12650	COG0735	belongs to the Fur family
EJ992_RS12655	COG1300	Membrane
EJ992_RS12660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS12680	COG2153	protein acetylation
EJ992_RS12685	COG1379	DNA repair
EJ992_RS12690	COG0494	nUDIX hydrolase
EJ992_RS12700	COG1309	transcriptional regulator
EJ992_RS12710	COG0667	Aldo Keto reductase
EJ992_RS12720	COG1073	alpha beta
EJ992_RS12730	COG4918	Iron-sulphur cluster biosynthesis
EJ992_RS12740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EJ992_RS12740	COG0456	acetyltransferase
EJ992_RS12745	COG2329	Antibiotic biosynthesis monooxygenase
EJ992_RS12755	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EJ992_RS12765	COG0747	negative chemotaxis
EJ992_RS12770	COG0601	transmembrane transport
EJ992_RS12775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS12780	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS12790	COG0534	Mate efflux family protein
EJ992_RS12805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EJ992_RS12815	COG2211	Major facilitator Superfamily
EJ992_RS12820	COG0346	lactoylglutathione lyase activity
EJ992_RS12825	COG1072	(Pantothenic acid kinase))
EJ992_RS12840	COG1131	(ABC) transporter
EJ992_RS12860	COG4195	phage-related replication protein
EJ992_RS12870	COG0300	oxidoreductase activity
EJ992_RS12875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS12880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJ992_RS12885	COG4187	Peptidase family M20/M25/M40
EJ992_RS12890	COG1902	pentaerythritol trinitrate reductase activity
EJ992_RS12895	COG0596	Alpha beta hydrolase
EJ992_RS12900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJ992_RS12905	COG1234	tRNA 3'-trailer cleavage
EJ992_RS12910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EJ992_RS12925	COG2358	TRAP transporter, solute receptor (TAXI family
EJ992_RS12930	COG2188	Transcriptional regulator
EJ992_RS12935	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS12945	COG1447	Phosphotransferase system cellobiose-specific component IIA
EJ992_RS12950	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS12955	COG1785	Belongs to the alkaline phosphatase family
EJ992_RS12960	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS12965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EJ992_RS12970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EJ992_RS12980	COG0706	membrane insertase activity
EJ992_RS12985	COG2195	Cleaves the N-terminal amino acid of tripeptides
EJ992_RS12990	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EJ992_RS12995	COG4129	membrane
EJ992_RS13000	COG1126	abc transporter atp-binding protein
EJ992_RS13005	COG0765	amino acid transport
EJ992_RS13020	COG1597	lipid kinase activity
EJ992_RS13025	COG0508	dehydrogenase complex catalyzes the overall conversion of
EJ992_RS13030	COG0022	dehydrogenase e1 component
EJ992_RS13035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EJ992_RS13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EJ992_RS13045	COG3426	butyrate kinase activity
EJ992_RS13055	COG0280	phosphate acetyltransferase
EJ992_RS13060	COG3290	protein histidine kinase activity
EJ992_RS13060	COG3829	transcription factor binding
EJ992_RS13070	COG0584	glycerophosphoryl diester phosphodiesterase
EJ992_RS13075	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS13090	COG1045	serine acetyltransferase
EJ992_RS13100	COG0745	RESPONSE REGULATOR receiver
EJ992_RS13105	COG0750	zinc metalloprotease
EJ992_RS13110	COG0497	DNA recombination
EJ992_RS13115	COG1438	arginine binding
EJ992_RS13120	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EJ992_RS13125	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EJ992_RS13130	COG0142	geranyltranstransferase activity
EJ992_RS13135	COG1722	exodeoxyribonuclease VII activity
EJ992_RS13140	COG1570	exodeoxyribonuclease VII activity
EJ992_RS13145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EJ992_RS13150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EJ992_RS13155	COG1302	Protein conserved in bacteria
EJ992_RS13160	COG0439	Biotin carboxylase
EJ992_RS13165	COG0511	ligase activity, forming carbon-carbon bonds
EJ992_RS13205	COG3854	ATPases associated with a variety of cellular activities
EJ992_RS13215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EJ992_RS13220	COG0006	proline dipeptidase activity
EJ992_RS13225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EJ992_RS13235	COG3872	metal-dependent enzyme
EJ992_RS13245	COG1752	Esterase of the alpha-beta hydrolase superfamily
EJ992_RS13250	COG1321	iron dependent repressor
EJ992_RS13255	COG0095	Lipoate-protein ligase
EJ992_RS13260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJ992_RS13265	COG2113	Glycine betaine
EJ992_RS13270	COG4176	ABC-type proline glycine betaine transport system permease component
EJ992_RS13275	COG0517	IMP dehydrogenase activity
EJ992_RS13275	COG4175	Glycine betaine
EJ992_RS13280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJ992_RS13285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EJ992_RS13290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EJ992_RS13295	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJ992_RS13320	COG0681	Belongs to the peptidase S26 family
EJ992_RS13345	COG4940	Competence protein ComGF
EJ992_RS13355	COG4970	Tfp pilus assembly protein FimT
EJ992_RS13360	COG4537	Required for transformation and DNA binding
EJ992_RS13365	COG1459	type II secretion system
EJ992_RS13370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EJ992_RS13375	COG1366	Belongs to the anti-sigma-factor antagonist family
EJ992_RS13385	COG1393	Belongs to the ArsC family
EJ992_RS13395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS13405	COG0011	TIGRFAM Protein of
EJ992_RS13415	COG2866	Carboxypeptidase
EJ992_RS13420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS13425	COG1368	sulfuric ester hydrolase activity
EJ992_RS13430	COG1940	carbohydrate kinase activity
EJ992_RS13435	COG4483	Protein conserved in bacteria
EJ992_RS13440	COG0697	spore germination
EJ992_RS13445	COG0457	Tetratricopeptide repeat
EJ992_RS13445	COG0705	Rhomboid family
EJ992_RS13450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EJ992_RS13455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EJ992_RS13460	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS13475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EJ992_RS13480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EJ992_RS13485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EJ992_RS13490	COG0581	inorganic phosphate transmembrane transporter activity
EJ992_RS13495	COG0573	inorganic phosphate transmembrane transporter activity
EJ992_RS13500	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EJ992_RS13505	COG0768	penicillin binding
EJ992_RS13510	COG0477	Major facilitator Superfamily
EJ992_RS13515	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EJ992_RS13520	COG2839	Protein conserved in bacteria
EJ992_RS13525	COG5521	maltodextrose utilization protein MalA
EJ992_RS13530	COG1388	LysM domain
EJ992_RS13535	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EJ992_RS13540	COG4709	membrane
EJ992_RS13545	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EJ992_RS13550	COG0735	belongs to the Fur family
EJ992_RS13555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EJ992_RS13560	COG1121	(ABC) transporter
EJ992_RS13565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS13575	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EJ992_RS13580	COG0513	Belongs to the DEAD box helicase family
EJ992_RS13590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EJ992_RS13595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EJ992_RS13600	COG2384	SAM-dependent methyltransferase
EJ992_RS13650	COG5444	nuclease activity
EJ992_RS13665	COG2010	Cytochrome c
EJ992_RS13670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EJ992_RS13675	COG0358	DNA primase activity
EJ992_RS13680	COG1671	Belongs to the UPF0178 family
EJ992_RS13685	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EJ992_RS13690	COG0517	IMP dehydrogenase activity
EJ992_RS13695	COG0751	glycine-tRNA ligase activity
EJ992_RS13700	COG0752	glycyl-tRNA synthetase alpha subunit
EJ992_RS13705	COG1381	Involved in DNA repair and RecF pathway recombination
EJ992_RS13715	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EJ992_RS13720	COG0295	cytidine deaminase activity
EJ992_RS13725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EJ992_RS13730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EJ992_RS13735	COG1480	7TM receptor with intracellular HD hydrolase
EJ992_RS13740	COG1702	phosphate starvation-inducible protein PhoH
EJ992_RS13745	COG0561	phosphatase activity
EJ992_RS13760	COG4864	UPF0365 protein
EJ992_RS13765	COG1030	water channel activity
EJ992_RS13770	COG1610	YqeY-like protein
EJ992_RS13775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EJ992_RS13780	COG1283	sodium-dependent phosphate transmembrane transporter activity
EJ992_RS13785	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EJ992_RS13790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EJ992_RS13795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EJ992_RS13800	COG2264	protein methyltransferase activity
EJ992_RS13805	COG0484	heat shock protein binding
EJ992_RS13810	COG0443	Heat shock 70 kDa protein
EJ992_RS13815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EJ992_RS13820	COG1420	regulation of RNA biosynthetic process
EJ992_RS13825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EJ992_RS13830	COG0481	GTPase activity
EJ992_RS13840	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS13845	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EJ992_RS13850	COG0268	Binds directly to 16S ribosomal RNA
EJ992_RS13855	COG1466	dna polymerase III delta subunit
EJ992_RS13865	COG0658	competence protein
EJ992_RS13865	COG2333	competence protein COMEC
EJ992_RS13870	COG2131	deaminase
EJ992_RS13875	COG1596	polysaccharide export
EJ992_RS13875	COG1555	photosystem II stabilization
EJ992_RS13880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EJ992_RS13885	COG2226	methyltransferase
EJ992_RS13890	COG0799	negative regulation of ribosome biogenesis
EJ992_RS13895	COG1713	HD superfamily hydrolase involved in NAD metabolism
EJ992_RS13900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EJ992_RS13905	COG1534	Rna-binding protein
EJ992_RS13910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EJ992_RS13915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EJ992_RS13920	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EJ992_RS13930	COG2755	lipolytic protein G-D-S-L family
EJ992_RS13935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS13940	COG5609	conserved protein (DUF2294)
EJ992_RS13945	COG3383	formate dehydrogenase (NAD+) activity
EJ992_RS13950	COG2427	Protein of unknown function (DUF1641)
EJ992_RS13970	COG1247	-acetyltransferase
EJ992_RS13985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJ992_RS13990	COG3616	Alanine racemase, N-terminal domain
EJ992_RS13995	COG0251	oxidation-reduction process
EJ992_RS14005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJ992_RS14010	COG0251	oxidation-reduction process
EJ992_RS14030	COG0789	Transcriptional regulator
EJ992_RS14030	COG4978	Transcriptional regulator
EJ992_RS14035	COG0425	Belongs to the sulfur carrier protein TusA family
EJ992_RS14035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJ992_RS14045	COG2197	response regulator
EJ992_RS14050	COG4585	Histidine kinase
EJ992_RS14055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS14060	COG0730	response to heat
EJ992_RS14065	COG0425	Belongs to the sulfur carrier protein TusA family
EJ992_RS14070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJ992_RS14070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS14075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJ992_RS14075	COG0425	Belongs to the sulfur carrier protein TusA family
EJ992_RS14080	COG2210	Belongs to the sulfur carrier protein TusA family
EJ992_RS14085	COG1937	Protein conserved in bacteria
EJ992_RS14130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EJ992_RS14135	COG0113	porphobilinogen synthase activity
EJ992_RS14145	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EJ992_RS14150	COG1733	regulation of RNA biosynthetic process
EJ992_RS14155	COG3239	Fatty acid desaturase
EJ992_RS14160	COG4585	Histidine kinase
EJ992_RS14165	COG2197	response regulator
EJ992_RS14170	COG0492	ferredoxin-NADP+ reductase activity
EJ992_RS14175	COG0747	negative chemotaxis
EJ992_RS14180	COG0601	transmembrane transport
EJ992_RS14185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EJ992_RS14190	COG0444	Belongs to the ABC transporter superfamily
EJ992_RS14195	COG4608	Belongs to the ABC transporter superfamily
EJ992_RS14215	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS14230	COG2124	cytochrome p450
EJ992_RS14235	COG0730	response to heat
EJ992_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS14255	COG1621	beta-fructofuranosidase activity
EJ992_RS14260	COG3716	PTS system mannose fructose sorbose family IID component
EJ992_RS14265	COG3715	PTS system
EJ992_RS14270	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS14275	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS14280	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EJ992_RS14280	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EJ992_RS14300	COG2169	Transcriptional regulator
EJ992_RS14305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EJ992_RS14310	COG0656	L-ascorbic acid biosynthetic process
EJ992_RS14315	COG2814	Major facilitator Superfamily
EJ992_RS14320	COG1733	regulation of RNA biosynthetic process
EJ992_RS14325	COG3340	Belongs to the peptidase S51 family
EJ992_RS14330	COG1587	Uroporphyrinogen-III synthase
EJ992_RS14340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS14345	COG0583	DNA-binding transcription factor activity
EJ992_RS14350	COG2814	Major facilitator Superfamily
EJ992_RS14360	COG2124	cytochrome p450
EJ992_RS14360	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EJ992_RS14365	COG1309	transcriptional regulator
EJ992_RS14370	COG1404	Belongs to the peptidase S8 family
EJ992_RS14375	COG2226	methyltransferase
EJ992_RS14400	COG0626	cystathionine gamma-synthase activity
EJ992_RS14405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJ992_RS14410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EJ992_RS14415	COG2226	methyltransferase
EJ992_RS14430	COG0768	penicillin binding
EJ992_RS14435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EJ992_RS14440	COG0572	uridine kinase
EJ992_RS14445	COG0826	peptidase U32
EJ992_RS14450	COG0826	peptidase U32
EJ992_RS14455	COG4122	O-methyltransferase activity
EJ992_RS14460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EJ992_RS14465	COG3906	Belongs to the UPF0473 family
EJ992_RS14470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EJ992_RS14475	COG4472	Bacterial protein of unknown function (DUF965)
EJ992_RS14480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EJ992_RS14485	COG0628	permease
EJ992_RS14500	COG3881	PFAM PRC-barrel domain
EJ992_RS14505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EJ992_RS14510	COG0457	Tetratricopeptide repeat
EJ992_RS14515	COG0482	sulfurtransferase activity
EJ992_RS14520	COG1104	cysteine desulfurase activity
EJ992_RS14525	COG1959	2 iron, 2 sulfur cluster binding
EJ992_RS14530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EJ992_RS14535	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EJ992_RS14545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EJ992_RS14550	COG0124	histidyl-tRNA synthetase
EJ992_RS14555	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS14555	COG3103	Sh3 type 3 domain protein
EJ992_RS14555	COG4991	sh3 domain protein
EJ992_RS14560	COG1490	D-aminoacyl-tRNA deacylase activity
EJ992_RS14565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EJ992_RS14570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EJ992_RS14575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EJ992_RS14575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EJ992_RS14580	COG5416	Lipopolysaccharide assembly protein A domain
EJ992_RS14585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJ992_RS14585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EJ992_RS14595	COG2244	polysaccharide biosynthetic process
EJ992_RS14600	COG2323	membrane
EJ992_RS14610	COG1862	Preprotein translocase
EJ992_RS14615	COG0343	queuine tRNA-ribosyltransferase activity
EJ992_RS14620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EJ992_RS14630	COG2255	four-way junction helicase activity
EJ992_RS14635	COG0632	four-way junction helicase activity
EJ992_RS14645	COG2112	serine threonine protein kinase
EJ992_RS14655	COG2318	DinB family
EJ992_RS14660	COG4195	phage-related replication protein
EJ992_RS14675	COG0217	transcriptional regulatory protein
EJ992_RS14685	COG1388	LysM domain
EJ992_RS14690	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EJ992_RS14695	COG0157	Belongs to the NadC ModD family
EJ992_RS14700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EJ992_RS14705	COG1104	cysteine desulfurase activity
EJ992_RS14710	COG1827	regulation of RNA biosynthetic process
EJ992_RS14715	COG0077	Prephenate dehydratase
EJ992_RS14720	COG4492	Belongs to the UPF0735 family
EJ992_RS14725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EJ992_RS14730	COG3290	protein histidine kinase activity
EJ992_RS14735	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EJ992_RS14740	COG2868	ribosomal protein
EJ992_RS14745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EJ992_RS14750	COG1994	Peptidase M50
EJ992_RS14755	COG0739	heme binding
EJ992_RS14760	COG3832	glyoxalase III activity
EJ992_RS14765	COG0640	Transcriptional regulator
EJ992_RS14770	COG2894	cell division
EJ992_RS14775	COG0850	regulation of cytokinetic process
EJ992_RS14780	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EJ992_RS14790	COG1077	Cell shape determining protein MreB Mrl
EJ992_RS14795	COG2003	Belongs to the UPF0758 family
EJ992_RS14800	COG0424	maF-like protein
EJ992_RS14810	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EJ992_RS14815	COG0285	dihydrofolate synthase activity
EJ992_RS14820	COG0525	valine-tRNA ligase activity
EJ992_RS14830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EJ992_RS14835	COG1388	LysM domain
EJ992_RS14840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EJ992_RS14845	COG0113	porphobilinogen synthase activity
EJ992_RS14850	COG1587	Uroporphyrinogen-III synthase
EJ992_RS14855	COG0181	hydroxymethylbilane synthase activity
EJ992_RS14860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EJ992_RS14865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EJ992_RS14875	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EJ992_RS14880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EJ992_RS14885	COG0470	DNA polymerase III
EJ992_RS14885	COG1067	ATP-dependent peptidase activity
EJ992_RS14890	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EJ992_RS14895	COG0544	peptidyl-prolyl cis-trans isomerase activity
EJ992_RS14900	COG1477	protein flavinylation
EJ992_RS14900	COG0457	Tetratricopeptide repeat
EJ992_RS14905	COG0066	3-isopropylmalate dehydratase activity
EJ992_RS14910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EJ992_RS14915	COG0473	3-isopropylmalate dehydrogenase activity
EJ992_RS14920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EJ992_RS14925	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EJ992_RS14930	COG0440	acetolactate synthase activity
EJ992_RS14935	COG0028	Belongs to the TPP enzyme family
EJ992_RS14940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJ992_RS14970	COG5518	Phage portal protein
EJ992_RS14975	COG1783	phage Terminase large subunit
EJ992_RS15015	COG5444	nuclease activity
EJ992_RS15020	COG0457	Tetratricopeptide repeat
EJ992_RS15040	COG0622	Phosphoesterase
EJ992_RS15045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EJ992_RS15050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EJ992_RS15055	COG5401	PFAM Sporulation and spore germination
EJ992_RS15060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EJ992_RS15065	COG1846	Transcriptional regulator
EJ992_RS15070	COG2197	response regulator
EJ992_RS15075	COG4221	oxidoreductase activity
EJ992_RS15080	COG0824	Thioesterase
EJ992_RS15085	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EJ992_RS15090	COG1053	succinate dehydrogenase
EJ992_RS15095	COG2009	succinate dehydrogenase
EJ992_RS15100	COG1719	4-vinyl reductase, 4VR
EJ992_RS15105	COG0527	aspartate kinase activity
EJ992_RS15115	COG0322	excinuclease ABC activity
EJ992_RS15120	COG3118	belongs to the thioredoxin family
EJ992_RS15125	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EJ992_RS15130	COG2086	electron transfer activity
EJ992_RS15135	COG1024	Enoyl-CoA hydratase
EJ992_RS15140	COG1309	transcriptional regulator
EJ992_RS15145	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS15150	COG3766	membrane
EJ992_RS15155	COG1193	negative regulation of DNA recombination
EJ992_RS15160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EJ992_RS15160	COG1796	DNA polymerase
EJ992_RS15165	COG1286	toxin biosynthetic process
EJ992_RS15170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EJ992_RS15175	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EJ992_RS15200	COG1137	ATPase activity
EJ992_RS15215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJ992_RS15215	COG0072	phenylalanine-tRNA ligase activity
EJ992_RS15220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EJ992_RS15225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EJ992_RS15235	COG1966	Carbon starvation protein
EJ992_RS15250	COG0395	ABC-type sugar transport system, permease component
EJ992_RS15255	COG1175	transmembrane transport
EJ992_RS15260	COG1653	transport
EJ992_RS15265	COG0371	Dehydrogenase
EJ992_RS15270	COG0235	Class ii aldolase
EJ992_RS15275	COG1069	ribulokinase activity
EJ992_RS15280	COG2160	L-arabinose isomerase activity
EJ992_RS15285	COG3507	Belongs to the glycosyl hydrolase 43 family
EJ992_RS15290	COG1363	Peptidase, m42
EJ992_RS15300	COG3326	Membrane
EJ992_RS15305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EJ992_RS15310	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EJ992_RS15315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EJ992_RS15320	COG1346	cytolysis
EJ992_RS15330	COG3540	Alkaline phosphatase
EJ992_RS15335	COG3279	Response regulator of the LytR AlgR family
EJ992_RS15340	COG3275	phosphorelay sensor kinase activity
EJ992_RS15350	COG1011	Hydrolase
EJ992_RS15355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EJ992_RS15365	COG0398	Pfam SNARE associated Golgi protein
EJ992_RS15370	COG1484	DNA-dependent DNA replication
EJ992_RS15375	COG3611	Membrane attachment protein
EJ992_RS15380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EJ992_RS15395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EJ992_RS15400	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EJ992_RS15405	COG3866	Pectate lyase
EJ992_RS15410	COG0237	dephospho-CoA kinase activity
EJ992_RS15415	COG1971	Probably functions as a manganese efflux pump
EJ992_RS15420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EJ992_RS15425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJ992_RS15425	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EJ992_RS15430	COG5002	protein histidine kinase activity
EJ992_RS15435	COG0745	RESPONSE REGULATOR receiver
EJ992_RS15440	COG0039	L-malate dehydrogenase activity
EJ992_RS15445	COG0538	isocitrate dehydrogenase activity
EJ992_RS15450	COG0372	Belongs to the citrate synthase family
EJ992_RS15455	COG2707	UPF0756 membrane protein
EJ992_RS15460	COG0628	permease
EJ992_RS15465	COG3030	protein affecting phage T7 exclusion by the F plasmid
EJ992_RS15475	COG0205	6-phosphofructokinase activity
EJ992_RS15480	COG0825	malonyl-CoA metabolic process
EJ992_RS15485	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EJ992_RS15490	COG0281	malic enzyme
EJ992_RS15495	COG0587	DNA-directed DNA polymerase activity
EJ992_RS15515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EJ992_RS15525	COG4109	DRTGG domain
EJ992_RS15530	COG1695	Transcriptional regulator
EJ992_RS15535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EJ992_RS15540	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS15545	COG0165	Argininosuccinate lyase
EJ992_RS15550	COG0137	argininosuccinate synthase activity
EJ992_RS15555	COG0521	Mo-molybdopterin cofactor biosynthetic process
EJ992_RS15560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EJ992_RS15565	COG0827	DNA restriction-modification system
EJ992_RS15570	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EJ992_RS15575	COG3874	Sporulation protein YtfJ
EJ992_RS15585	COG1714	RDD family
EJ992_RS15590	COG0616	signal peptide processing
EJ992_RS15595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EJ992_RS15600	COG1566	PFAM secretion protein HlyD family protein
EJ992_RS15605	COG0477	Major facilitator Superfamily
EJ992_RS15615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJ992_RS15625	COG0301	tRNA thio-modification
EJ992_RS15630	COG1104	cysteine desulfurase activity
EJ992_RS15635	COG1114	Component of the transport system for branched-chain amino acids
EJ992_RS15645	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EJ992_RS15650	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EJ992_RS15655	COG1309	transcriptional regulator
EJ992_RS15660	COG1956	GAF domain-containing protein
EJ992_RS15665	COG2199	diguanylate cyclase activity
EJ992_RS15665	COG2203	Gaf domain
EJ992_RS15670	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EJ992_RS15685	COG3152	Membrane
EJ992_RS15690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EJ992_RS15695	COG1522	sequence-specific DNA binding
EJ992_RS15700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EJ992_RS15705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EJ992_RS15710	COG0454	-acetyltransferase
EJ992_RS15715	COG0517	IMP dehydrogenase activity
EJ992_RS15720	COG0123	including yeast histone deacetylase and acetoin utilization protein
EJ992_RS15725	COG1360	Flagellar Motor Protein
EJ992_RS15730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EJ992_RS15735	COG1609	Transcriptional regulator
EJ992_RS15740	COG1605	Chorismate mutase
EJ992_RS15740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EJ992_RS15750	COG3118	belongs to the thioredoxin family
EJ992_RS15755	COG4980	gas vesicle protein
EJ992_RS15760	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EJ992_RS15765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EJ992_RS15770	COG1674	ftsk spoiiie
EJ992_RS15775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EJ992_RS15780	COG4848	Belongs to the UPF0354 family
EJ992_RS15785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS15795	COG1363	Peptidase, m42
EJ992_RS15800	COG5584	Small secreted protein
EJ992_RS15805	COG0281	malic enzyme
EJ992_RS15810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EJ992_RS15815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EJ992_RS15825	COG0510	thiamine kinase activity
EJ992_RS15830	COG1523	belongs to the glycosyl hydrolase 13 family
EJ992_RS15835	COG1597	lipid kinase activity
EJ992_RS15845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EJ992_RS15850	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EJ992_RS15865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJ992_RS15870	COG2252	PERMEase
EJ992_RS15875	COG1349	DNA-binding transcription factor activity
EJ992_RS15880	COG1187	pseudouridine synthase activity
EJ992_RS15885	COG2244	polysaccharide biosynthetic process
EJ992_RS15890	COG2081	HI0933 family
EJ992_RS15895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EJ992_RS15905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EJ992_RS15910	COG0457	Tetratricopeptide repeat
EJ992_RS15920	COG5578	integral membrane protein
EJ992_RS15925	COG0673	inositol 2-dehydrogenase activity
EJ992_RS15930	COG1653	transport
EJ992_RS15935	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EJ992_RS15940	COG4209	transmembrane transport
EJ992_RS15945	COG2207	Transcriptional regulator
EJ992_RS15950	COG1653	transport
EJ992_RS15955	COG0395	ABC-type sugar transport system, permease component
EJ992_RS15960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJ992_RS15965	COG1073	alpha beta
EJ992_RS15975	COG0583	DNA-binding transcription factor activity
EJ992_RS15980	COG0346	lactoylglutathione lyase activity
EJ992_RS15985	COG0495	leucyl-tRNA aminoacylation
EJ992_RS15995	COG2814	Major facilitator Superfamily
EJ992_RS16005	COG2433	Pfam Transposase IS66
EJ992_RS16010	COG0577	efflux transmembrane transporter activity
EJ992_RS16015	COG1136	(ABC) transporter
EJ992_RS16025	COG1131	(ABC) transporter
EJ992_RS16030	COG1725	Transcriptional regulator
EJ992_RS16040	COG1242	4 iron, 4 sulfur cluster binding
EJ992_RS16045	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EJ992_RS16050	COG1301	dicarboxylic acid transport
EJ992_RS16060	COG2267	carboxylic ester hydrolase activity
EJ992_RS16065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EJ992_RS16070	COG0671	phosphoesterase, PA-phosphatase related
EJ992_RS16075	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJ992_RS16075	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS16080	COG0367	asparagine synthase
EJ992_RS16085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EJ992_RS16090	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EJ992_RS16105	COG1506	peptidase
EJ992_RS16110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EJ992_RS16115	COG1116	anion transmembrane transporter activity
EJ992_RS16120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EJ992_RS16125	COG0494	nUDIX hydrolase
EJ992_RS16135	COG4824	toxin secretion phage lysis holin
EJ992_RS16140	COG0783	Belongs to the Dps family
EJ992_RS16155	COG1854	S-ribosylhomocysteine lyase activity
EJ992_RS16160	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EJ992_RS16165	COG0288	reversible hydration of carbon dioxide
EJ992_RS16170	COG0523	cobalamin synthesis protein
EJ992_RS16175	COG0803	Belongs to the bacterial solute-binding protein 9 family
EJ992_RS16180	COG0254	rRNA binding
EJ992_RS16185	COG1271	oxidase subunit
EJ992_RS16190	COG1294	oxidase, subunit
EJ992_RS16205	COG4948	Mandelate Racemase Muconate Lactonizing
EJ992_RS16210	COG0318	PFAM AMP-dependent synthetase and ligase
EJ992_RS16215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EJ992_RS16220	COG0596	Alpha beta hydrolase
EJ992_RS16225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EJ992_RS16230	COG1169	isochorismate synthase
EJ992_RS16235	COG1575	Belongs to the MenA family. Type 1 subfamily
EJ992_RS16240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EJ992_RS16245	COG0058	SHG alpha-glucan phosphorylase activity
EJ992_RS16250	COG0297	glycogen (starch) synthase activity
EJ992_RS16255	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EJ992_RS16260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EJ992_RS16265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EJ992_RS16390	COG1609	Transcriptional regulator
EJ992_RS16395	COG3859	Proton-coupled thiamine transporter YuaJ
EJ992_RS16400	COG3764	Sortase (surface protein transpeptidase)
EJ992_RS16415	COG0457	Tetratricopeptide repeat
EJ992_RS16420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EJ992_RS16425	COG0569	domain protein
EJ992_RS16430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EJ992_RS16440	COG2318	DinB family
EJ992_RS16450	COG1454	alcohol dehydrogenase
EJ992_RS16455	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS16460	COG1510	regulation of RNA biosynthetic process
EJ992_RS16470	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EJ992_RS16475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EJ992_RS16525	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EJ992_RS16535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EJ992_RS16540	COG0726	polysaccharide deacetylase
EJ992_RS16545	COG1408	metallophosphoesterase
EJ992_RS16550	COG1968	undecaprenyl-diphosphatase activity
EJ992_RS16555	COG0628	permease
EJ992_RS16560	COG0673	inositol 2-dehydrogenase activity
EJ992_RS16565	COG0693	protein deglycase activity
EJ992_RS16570	COG0840	transmembrane signaling receptor activity
EJ992_RS16575	COG0840	transmembrane signaling receptor activity
EJ992_RS16580	COG0840	transmembrane signaling receptor activity
EJ992_RS16590	COG2070	2-Nitropropane dioxygenase
EJ992_RS16595	COG0432	Pfam Uncharacterised protein family UPF0047
EJ992_RS16600	COG0366	Alpha amylase catalytic
EJ992_RS16615	COG5297	Belongs to the glycosyl hydrolase family 6
EJ992_RS16620	COG1253	flavin adenine dinucleotide binding
EJ992_RS16625	COG2738	Putative neutral zinc metallopeptidase
EJ992_RS16640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EJ992_RS16650	COG2323	membrane
EJ992_RS16655	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EJ992_RS16665	COG0166	Belongs to the GPI family
EJ992_RS16670	COG1979	alcohol dehydrogenase
EJ992_RS16675	COG2155	Conserved Protein
EJ992_RS16680	COG1098	S1 RNA binding domain
EJ992_RS16685	COG0436	Aminotransferase
EJ992_RS16690	COG1522	sequence-specific DNA binding
EJ992_RS16695	COG2267	carboxylic ester hydrolase activity
EJ992_RS16710	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EJ992_RS16725	COG5018	Exonuclease
EJ992_RS16730	COG2814	Major facilitator Superfamily
EJ992_RS16735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJ992_RS16740	COG3011	Protein conserved in bacteria
EJ992_RS16750	COG3290	protein histidine kinase activity
EJ992_RS16755	COG4565	transcriptional regulatory protein
EJ992_RS16765	COG1183	phosphatidylcholine synthase activity
EJ992_RS16770	COG0586	Pfam SNARE associated Golgi protein
EJ992_RS16775	COG0688	phosphatidylethanolamine metabolic process
EJ992_RS16785	COG3493	citrate carrier protein
EJ992_RS16795	COG2111	Na H antiporter
EJ992_RS16795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EJ992_RS16800	COG2111	Na H antiporter
EJ992_RS16805	COG1006	Multisubunit Na H antiporter MnhC subunit
EJ992_RS16810	COG0651	ATP synthesis coupled electron transport
EJ992_RS16815	COG1863	multisubunit Na H antiporter MnhE subunit
EJ992_RS16820	COG2212	antiporter activity
EJ992_RS16825	COG1320	monovalent cation:proton antiporter activity
EJ992_RS16830	COG2050	protein possibly involved in aromatic compounds catabolism
EJ992_RS16835	COG2197	response regulator
EJ992_RS16880	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EJ992_RS16885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EJ992_RS16890	COG1335	isochorismatase
EJ992_RS16895	COG5506	Protein of unknown function (DUF1694)
EJ992_RS16910	COG0628	permease
EJ992_RS16915	COG1959	2 iron, 2 sulfur cluster binding
EJ992_RS16920	COG0657	acetylesterase activity
EJ992_RS16930	COG1418	mRNA catabolic process
EJ992_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS16945	COG1511	domain protein
EJ992_RS16950	COG0433	COG0433 Predicted ATPase
EJ992_RS16950	COG1674	ftsk spoiiie
EJ992_RS16955	COG4499	WXG100 protein secretion system (Wss), protein YukC
EJ992_RS16960	COG5417	Belongs to the EsaB family
EJ992_RS16965	COG4842	Belongs to the WXG100 family
EJ992_RS16970	COG1115	amino acid carrier protein
EJ992_RS16975	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EJ992_RS16975	COG2508	Transcriptional regulator
EJ992_RS16980	COG0686	Belongs to the AlaDH PNT family
EJ992_RS16990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EJ992_RS16995	COG1268	BioY protein
EJ992_RS17000	COG2056	Na+-H+ antiporter family
EJ992_RS17005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EJ992_RS17010	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EJ992_RS17015	COG3584	3D domain protein
EJ992_RS17025	COG1252	NADH dehydrogenase
EJ992_RS17030	COG0492	ferredoxin-NADP+ reductase activity
EJ992_RS17045	COG0456	acetyltransferase
EJ992_RS17050	COG0316	Belongs to the HesB IscA family
EJ992_RS17055	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EJ992_RS17060	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EJ992_RS17065	COG4844	belongs to the
EJ992_RS17070	COG1252	NADH dehydrogenase
EJ992_RS17075	COG5646	InterPro IPR014922
EJ992_RS17085	COG0457	Tetratricopeptide repeat
EJ992_RS17090	COG3479	Phenolic acid decarboxylase
EJ992_RS17100	COG4837	Protein of unknown function (DUF1462)
EJ992_RS17105	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EJ992_RS17110	COG4946	Tricorn protease homolog
EJ992_RS17110	COG0823	Involved in the tonB-independent uptake of proteins
EJ992_RS17110	COG1506	peptidase
EJ992_RS17115	COG0083	homoserine kinase activity
EJ992_RS17120	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EJ992_RS17125	COG0460	homoserine dehydrogenase
EJ992_RS17135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EJ992_RS17140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EJ992_RS17145	COG0647	UMP catabolic process
EJ992_RS17150	COG2445	Protein of unknown function DUF86
EJ992_RS17155	COG4470	Protein conserved in bacteria
EJ992_RS17170	COG0739	heme binding
EJ992_RS17180	COG0733	neurotransmitter:sodium symporter activity
EJ992_RS17190	COG3377	Domain of unknown function (DUF1805)
EJ992_RS17195	COG0737	Belongs to the 5'-nucleotidase family
EJ992_RS17200	COG0730	response to heat
EJ992_RS17205	COG1801	Protein of unknown function DUF72
EJ992_RS17215	COG3226	Transcriptional regulator
EJ992_RS17225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EJ992_RS17230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EJ992_RS17235	COG2508	Transcriptional regulator
EJ992_RS17240	COG2814	Major facilitator Superfamily
EJ992_RS17245	COG1288	antiporter activity
EJ992_RS17250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJ992_RS17255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EJ992_RS17260	COG2356	endonuclease I
EJ992_RS17270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EJ992_RS17285	COG0457	Tetratricopeptide repeat
EJ992_RS17290	COG0719	Fe-S assembly protein
EJ992_RS17295	COG0822	iron-sulfur transferase activity
EJ992_RS17300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJ992_RS17305	COG0719	Fe-S assembly protein
EJ992_RS17310	COG0396	ATPase activity
EJ992_RS17320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJ992_RS17325	COG1464	Belongs to the NlpA lipoprotein family
EJ992_RS17330	COG2011	ABC-type metal ion transport system permease component
EJ992_RS17335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EJ992_RS17345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EJ992_RS17350	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EJ992_RS17360	COG0509	glycine decarboxylation via glycine cleavage system
EJ992_RS17365	COG1393	Belongs to the ArsC family
EJ992_RS17370	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS17375	COG0183	Belongs to the thiolase family
EJ992_RS17380	COG1024	Enoyl-CoA hydratase
EJ992_RS17380	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJ992_RS17395	COG5577	PFAM Coat F domain
EJ992_RS17410	COG1120	ATPase activity
EJ992_RS17415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS17420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS17425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS17440	COG1686	Belongs to the peptidase S11 family
EJ992_RS17445	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS17450	COG0783	Belongs to the Dps family
EJ992_RS17455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJ992_RS17460	COG0745	RESPONSE REGULATOR receiver
EJ992_RS17465	COG2770	Histidine kinase
EJ992_RS17465	COG2205	protein histidine kinase activity
EJ992_RS17470	COG1309	transcriptional regulator
EJ992_RS17475	COG0114	fumarate hydratase activity
EJ992_RS17485	COG0697	spore germination
EJ992_RS17490	COG0814	amino acid
EJ992_RS17505	COG2197	response regulator
EJ992_RS17510	COG4585	Histidine kinase
EJ992_RS17515	COG4758	membrane
EJ992_RS17525	COG1842	Phage shock protein A
EJ992_RS17530	COG4758	membrane
EJ992_RS17535	COG4677	pectinesterase activity
EJ992_RS17540	COG2096	Adenosyltransferase
EJ992_RS17545	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS17560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJ992_RS17565	COG1120	ATPase activity
EJ992_RS17570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS17575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS17580	COG1802	Transcriptional regulator
EJ992_RS17585	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS17590	COG2258	MOSC domain
EJ992_RS17595	COG0583	DNA-binding transcription factor activity
EJ992_RS17605	COG2721	sulfolactate sulfo-lyase activity
EJ992_RS17610	COG0246	Mannitol dehydrogenase
EJ992_RS17615	COG1609	Transcriptional regulator
EJ992_RS17620	COG2211	Major facilitator Superfamily
EJ992_RS17625	COG1904	glucuronate isomerase
EJ992_RS17630	COG2205	protein histidine kinase activity
EJ992_RS17635	COG0745	RESPONSE REGULATOR receiver
EJ992_RS17640	COG1120	ATPase activity
EJ992_RS17645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS17650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS17655	COG0531	amino acid
EJ992_RS17665	COG1988	membrane-bound metal-dependent
EJ992_RS17670	COG1368	sulfuric ester hydrolase activity
EJ992_RS17675	COG2814	Major facilitator Superfamily
EJ992_RS17680	COG0656	L-ascorbic acid biosynthetic process
EJ992_RS17685	COG1940	carbohydrate kinase activity
EJ992_RS17690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EJ992_RS17700	COG3973	AAA domain
EJ992_RS17705	COG2860	membrane
EJ992_RS17710	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EJ992_RS17710	COG0456	acetyltransferase
EJ992_RS17715	COG0456	acetyltransferase
EJ992_RS17720	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EJ992_RS17725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EJ992_RS17730	COG2217	Heavy metal translocating P-type atpase
EJ992_RS17735	COG1653	transport
EJ992_RS17740	COG1175	transmembrane transport
EJ992_RS17745	COG0395	ABC-type sugar transport system, permease component
EJ992_RS17750	COG1501	Belongs to the glycosyl hydrolase 31 family
EJ992_RS17755	COG1472	Belongs to the glycosyl hydrolase 3 family
EJ992_RS17760	COG1121	(ABC) transporter
EJ992_RS17765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EJ992_RS17770	COG0803	Belongs to the bacterial solute-binding protein 9 family
EJ992_RS17785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EJ992_RS17785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EJ992_RS17790	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS17790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS17790	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EJ992_RS17805	COG2217	Heavy metal translocating P-type atpase
EJ992_RS17810	COG2608	mercury ion transmembrane transporter activity
EJ992_RS17815	COG1937	Protein conserved in bacteria
EJ992_RS17820	COG0693	protein deglycase activity
EJ992_RS17825	COG1349	DNA-binding transcription factor activity
EJ992_RS17830	COG1070	Carbohydrate kinase
EJ992_RS17835	COG4952	isomerase
EJ992_RS17845	COG3347	Dehydrogenase
EJ992_RS17845	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS17850	COG2814	Major facilitator Superfamily
EJ992_RS17855	COG2814	Major facilitator Superfamily
EJ992_RS17865	COG2124	cytochrome p450
EJ992_RS17875	COG1846	Transcriptional regulator
EJ992_RS17885	COG0673	inositol 2-dehydrogenase activity
EJ992_RS17890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EJ992_RS17895	COG1054	Belongs to the UPF0176 family
EJ992_RS17905	COG1191	sigma factor activity
EJ992_RS17915	COG2140	Oxalate decarboxylase
EJ992_RS17960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EJ992_RS17990	COG5444	nuclease activity
EJ992_RS18035	COG1705	Flagellar rod assembly protein muramidase FlgJ
EJ992_RS18045	COG5280	Phage tail tape measure protein TP901
EJ992_RS18045	COG3953	SLT domain
EJ992_RS18105	COG4626	Terminase
EJ992_RS18105	COG1802	Transcriptional regulator
EJ992_RS18245	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EJ992_RS18250	COG0557	exoribonuclease II activity
EJ992_RS18255	COG1647	Serine aminopeptidase, S33
EJ992_RS18260	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EJ992_RS18265	COG2002	toxin-antitoxin pair type II binding
EJ992_RS18270	COG1476	TRANSCRIPTIONal
EJ992_RS18275	COG1396	sequence-specific DNA binding
EJ992_RS18280	COG1396	sequence-specific DNA binding
EJ992_RS18285	COG1174	glycine betaine transport
EJ992_RS18290	COG1732	Glycine betaine
EJ992_RS18295	COG1174	glycine betaine transport
EJ992_RS18300	COG0517	IMP dehydrogenase activity
EJ992_RS18300	COG1125	glycine betaine transport
EJ992_RS18305	COG1510	regulation of RNA biosynthetic process
EJ992_RS18310	COG2095	MarC family integral membrane protein
EJ992_RS18315	COG3064	Membrane
EJ992_RS18325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS18345	COG0148	phosphopyruvate hydratase activity
EJ992_RS18350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EJ992_RS18355	COG0149	triose-phosphate isomerase activity
EJ992_RS18360	COG0126	phosphoglycerate kinase activity
EJ992_RS18370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EJ992_RS18375	COG2390	Transcriptional regulator
EJ992_RS18380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJ992_RS18385	COG1113	amino acid transport
EJ992_RS18405	COG1556	Lactate utilization protein
EJ992_RS18410	COG1139	Iron-sulfur cluster binding protein
EJ992_RS18415	COG0247	lactate metabolic process
EJ992_RS18420	COG2186	Transcriptional regulator
EJ992_RS18425	COG1620	l-lactate permease
EJ992_RS18430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EJ992_RS18440	COG5039	Polysaccharide pyruvyl transferase
EJ992_RS18445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJ992_RS18450	COG0110	maltose O-acetyltransferase activity
EJ992_RS18455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EJ992_RS18460	COG2244	polysaccharide biosynthetic process
EJ992_RS18465	COG1216	Glycosyl transferase, family 2
EJ992_RS18470	COG5039	Polysaccharide pyruvyl transferase
EJ992_RS18475	COG1216	Glycosyl transferase, family 2
EJ992_RS18485	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS18490	COG1215	transferase activity, transferring glycosyl groups
EJ992_RS18495	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS18500	COG1086	Polysaccharide biosynthesis protein
EJ992_RS18505	COG0489	protein tyrosine kinase activity
EJ992_RS18510	COG3944	biosynthesis protein
EJ992_RS18515	COG1396	sequence-specific DNA binding
EJ992_RS18520	COG2249	NAD(P)H dehydrogenase (quinone) activity
EJ992_RS18525	COG2271	Major facilitator Superfamily
EJ992_RS18535	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EJ992_RS18550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EJ992_RS18560	COG1733	regulation of RNA biosynthetic process
EJ992_RS18565	COG1902	pentaerythritol trinitrate reductase activity
EJ992_RS18570	COG1621	beta-fructofuranosidase activity
EJ992_RS18575	COG1621	beta-fructofuranosidase activity
EJ992_RS18590	COG0740	serine-type endopeptidase activity
EJ992_RS18595	COG1611	Belongs to the LOG family
EJ992_RS18600	COG1694	Mazg nucleotide pyrophosphohydrolase
EJ992_RS18605	COG1078	dGTPase activity
EJ992_RS18610	COG0659	secondary active sulfate transmembrane transporter activity
EJ992_RS18615	COG0288	reversible hydration of carbon dioxide
EJ992_RS18620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EJ992_RS18625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EJ992_RS18630	COG0640	Transcriptional regulator
EJ992_RS18640	COG2732	(Barnase) inhibitor
EJ992_RS18645	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EJ992_RS18650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS18655	COG1481	regulation of sporulation
EJ992_RS18660	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EJ992_RS18665	COG1660	Displays ATPase and GTPase activities
EJ992_RS18670	COG1051	belongs to the nudix hydrolase family
EJ992_RS18680	COG0492	ferredoxin-NADP+ reductase activity
EJ992_RS18685	COG0457	Tetratricopeptide repeat
EJ992_RS18690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EJ992_RS18695	COG0140	phosphoribosyl-ATP diphosphatase activity
EJ992_RS18695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EJ992_RS18700	COG0107	imidazoleglycerol-phosphate synthase activity
EJ992_RS18705	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EJ992_RS18710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EJ992_RS18715	COG0131	Imidazoleglycerol-phosphate dehydratase
EJ992_RS18720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EJ992_RS18725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EJ992_RS18730	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EJ992_RS18735	COG4990	cell redox homeostasis
EJ992_RS18740	COG5297	Belongs to the glycosyl hydrolase family 6
EJ992_RS18745	COG0110	maltose O-acetyltransferase activity
EJ992_RS18750	COG0546	phosphoglycolate phosphatase activity
EJ992_RS18755	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EJ992_RS18760	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EJ992_RS18765	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EJ992_RS18770	COG1846	Transcriptional regulator
EJ992_RS18775	COG2814	Major facilitator Superfamily
EJ992_RS18780	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EJ992_RS18785	COG1950	PFAM Membrane protein of
EJ992_RS18790	COG1983	PspC domain protein
EJ992_RS18795	COG3595	metallopeptidase activity
EJ992_RS18820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EJ992_RS18825	COG0556	nucleotide-excision repair
EJ992_RS18830	COG4897	Protein conserved in bacteria
EJ992_RS18840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJ992_RS18850	COG3409	Peptidoglycan-binding domain 1 protein
EJ992_RS18850	COG0793	Belongs to the peptidase S41A family
EJ992_RS18855	COG0473	3-isopropylmalate dehydrogenase activity
EJ992_RS18860	COG3883	PFAM NLP P60 protein
EJ992_RS18860	COG0791	NLP P60 protein
EJ992_RS18865	COG2177	Part of the ABC transporter FtsEX involved in
EJ992_RS18870	COG2884	Cell division ATP-binding protein ftsE
EJ992_RS18880	COG2010	Cytochrome c
EJ992_RS18885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS18895	COG0653	protein targeting
EJ992_RS18900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EJ992_RS18915	COG1516	flagellar protein fliS
EJ992_RS18920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EJ992_RS18925	COG1334	flagellar protein FlaG
EJ992_RS18930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EJ992_RS18935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EJ992_RS18940	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EJ992_RS18950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EJ992_RS18955	COG1256	bacterial-type flagellum assembly
EJ992_RS18955	COG4786	Flagellar basal body rod
EJ992_RS18960	COG3418	PFAM FlgN family protein
EJ992_RS18965	COG2747	anti-sigma28 factor FlgM
EJ992_RS18975	COG1040	competence protein
EJ992_RS18985	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EJ992_RS18990	COG1307	EDD domain protein, DegV family
EJ992_RS18995	COG2197	response regulator
EJ992_RS19000	COG4585	Histidine kinase
EJ992_RS19005	COG1739	Uncharacterized protein family UPF0029
EJ992_RS19010	COG1316	TRANSCRIPTIONal
EJ992_RS19020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EJ992_RS19025	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS19030	COG1215	transferase activity, transferring glycosyl groups
EJ992_RS19035	COG3206	protein involved in exopolysaccharide biosynthesis
EJ992_RS19040	COG3307	-O-antigen
EJ992_RS19045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EJ992_RS19050	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EJ992_RS19055	COG0438	transferase activity, transferring glycosyl groups
EJ992_RS19055	COG0297	glycogen (starch) synthase activity
EJ992_RS19060	COG2244	polysaccharide biosynthetic process
EJ992_RS19070	COG0860	N-Acetylmuramoyl-L-alanine amidase
EJ992_RS19070	COG2247	cell wall binding repeat
EJ992_RS19075	COG2247	cell wall binding repeat
EJ992_RS19075	COG2385	sporulation resulting in formation of a cellular spore
EJ992_RS19085	COG1316	TRANSCRIPTIONal
EJ992_RS19095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EJ992_RS19100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EJ992_RS19105	COG1134	teichoic acid transport
EJ992_RS19110	COG1682	transport, permease protein
EJ992_RS19115	COG0463	Glycosyl transferase, family 2
EJ992_RS19115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EJ992_RS19120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EJ992_RS19125	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EJ992_RS19130	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EJ992_RS19135	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EJ992_RS19140	COG4193	domain, Protein
EJ992_RS19145	COG1482	cell wall glycoprotein biosynthetic process
EJ992_RS19165	COG0800	Aldolase
EJ992_RS19170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJ992_RS19175	COG1609	Transcriptional regulator
EJ992_RS19180	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EJ992_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS19190	COG1063	alcohol dehydrogenase
EJ992_RS19200	COG1316	TRANSCRIPTIONal
EJ992_RS19205	COG0561	phosphatase activity
EJ992_RS19210	COG0791	NLP P60 protein
EJ992_RS19215	COG2843	Capsule synthesis protein
EJ992_RS19225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EJ992_RS19230	COG1609	Transcriptional regulator
EJ992_RS19235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJ992_RS19240	COG1869	D-ribose catabolic process
EJ992_RS19245	COG1129	ABC transporter
EJ992_RS19250	COG1172	Belongs to the binding-protein-dependent transport system permease family
EJ992_RS19255	COG1879	ABC-type sugar transport system periplasmic component
EJ992_RS19265	COG3527	Alpha-acetolactate decarboxylase
EJ992_RS19270	COG0028	Belongs to the TPP enzyme family
EJ992_RS19275	COG0583	DNA-binding transcription factor activity
EJ992_RS19280	COG0405	Gamma-glutamyltransferase
EJ992_RS19285	COG1522	sequence-specific DNA binding
EJ992_RS19290	COG2059	Chromate
EJ992_RS19295	COG2059	Chromate
EJ992_RS19300	COG4464	protein tyrosine phosphatase activity
EJ992_RS19305	COG3944	biosynthesis protein
EJ992_RS19315	COG4715	Zinc finger, swim domain protein
EJ992_RS19320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EJ992_RS19325	COG0561	phosphatase activity
EJ992_RS19330	COG1349	DNA-binding transcription factor activity
EJ992_RS19340	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS19350	COG3732	PTS system glucitol sorbitol-specific
EJ992_RS19370	COG0629	single-stranded DNA binding
EJ992_RS19385	COG1970	mechanosensitive ion channel activity
EJ992_RS19390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EJ992_RS19395	COG4786	Flagellar basal body rod
EJ992_RS19400	COG4786	Flagellar basal body rod
EJ992_RS19405	COG1077	Cell shape determining protein MreB Mrl
EJ992_RS19410	COG1609	Transcriptional regulator
EJ992_RS19420	COG1846	Transcriptional regulator
EJ992_RS19425	COG2814	Major facilitator Superfamily
EJ992_RS19430	COG0671	phosphoesterase, PA-phosphatase related
EJ992_RS19435	COG1227	inorganic diphosphatase activity
EJ992_RS19440	COG3546	catalase activity
EJ992_RS19445	COG3361	conserved protein (COG2071)
EJ992_RS19450	COG0517	IMP dehydrogenase activity
EJ992_RS19455	COG0598	Magnesium transport protein CorA
EJ992_RS19460	COG1253	flavin adenine dinucleotide binding
EJ992_RS19465	COG0004	ammonium transporteR
EJ992_RS19470	COG0347	Belongs to the P(II) protein family
EJ992_RS19475	COG0740	serine-type endopeptidase activity
EJ992_RS19485	COG0739	heme binding
EJ992_RS19490	COG1247	-acetyltransferase
EJ992_RS19500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EJ992_RS19505	COG0477	Major facilitator Superfamily
EJ992_RS19510	COG3251	PFAM MbtH domain protein
EJ992_RS19515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS19520	COG1535	isochorismatase
EJ992_RS19520	COG3433	isochorismatase activity
EJ992_RS19525	COG1021	2,3-dihydroxybenzoate-AMP ligase
EJ992_RS19530	COG1169	isochorismate synthase
EJ992_RS19535	COG1028	Short-chain dehydrogenase reductase Sdr
EJ992_RS19540	COG2819	hydrolase of the alpha beta superfamily
EJ992_RS19545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS19550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EJ992_RS19555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS19560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS19560	COG2207	Transcriptional regulator
EJ992_RS19575	COG2910	NAD(P)H-binding
EJ992_RS19580	COG1959	2 iron, 2 sulfur cluster binding
EJ992_RS19590	COG1994	Peptidase M50
EJ992_RS19595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EJ992_RS19600	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EJ992_RS19605	COG2223	nitrite transmembrane transporter activity
EJ992_RS19610	COG3383	formate dehydrogenase (NAD+) activity
EJ992_RS19615	COG2304	oxidoreductase activity
EJ992_RS19620	COG2304	oxidoreductase activity
EJ992_RS19625	COG2385	sporulation resulting in formation of a cellular spore
EJ992_RS19630	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJ992_RS19640	COG4836	Membrane
EJ992_RS19645	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EJ992_RS19650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EJ992_RS19655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EJ992_RS19660	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EJ992_RS19665	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJ992_RS19670	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EJ992_RS19675	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EJ992_RS19695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EJ992_RS19700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EJ992_RS19705	COG4475	Protein of unknown function (DUF436)
EJ992_RS19710	COG0698	ribose 5-phosphate isomerase
EJ992_RS19715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EJ992_RS19720	COG1971	Probably functions as a manganese efflux pump
EJ992_RS19725	COG0009	L-threonylcarbamoyladenylate synthase
EJ992_RS19730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EJ992_RS19740	COG0738	Major facilitator superfamily
EJ992_RS19745	COG0673	inositol 2-dehydrogenase activity
EJ992_RS19750	COG0561	phosphatase activity
EJ992_RS19755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EJ992_RS19760	COG1609	Transcriptional regulator
EJ992_RS19765	COG2890	protein-(glutamine-N5) methyltransferase activity
EJ992_RS19770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EJ992_RS19775	COG0346	lactoylglutathione lyase activity
EJ992_RS19780	COG0789	Transcriptional regulator
EJ992_RS19785	COG0679	Auxin Efflux Carrier
EJ992_RS19790	COG0281	malic enzyme
EJ992_RS19795	COG1435	thymidine kinase activity
EJ992_RS19800	COG0254	rRNA binding
EJ992_RS19805	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EJ992_RS19810	COG1494	fructose-1,6-bisphosphatase
EJ992_RS19815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EJ992_RS19820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EJ992_RS19825	COG0191	fructose-bisphosphate aldolase activity
EJ992_RS19830	COG2204	response regulator
EJ992_RS19835	COG4821	SIS domain
EJ992_RS19840	COG0504	CTP synthase activity
EJ992_RS19845	COG3343	RNA polymerase activity
EJ992_RS19850	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS19855	COG1960	acyl-CoA dehydrogenase activity
EJ992_RS19860	COG1250	3-hydroxyacyl-CoA dehydrogenase
EJ992_RS19865	COG0183	Belongs to the thiolase family
EJ992_RS19870	COG0247	lactate metabolic process
EJ992_RS19870	COG2181	nitrate reductase activity
EJ992_RS19875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EJ992_RS19885	COG0018	arginyl-trna synthetase
EJ992_RS19890	COG4506	Protein conserved in bacteria
EJ992_RS19895	COG0010	Belongs to the arginase family
EJ992_RS19900	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EJ992_RS19915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EJ992_RS19925	COG1994	Peptidase M50
EJ992_RS19930	COG1942	4-Oxalocrotonate Tautomerase
EJ992_RS19940	COG3465	dGTPase activity
EJ992_RS19945	COG1078	dGTPase activity
EJ992_RS19950	COG4844	belongs to the
EJ992_RS19975	COG2814	Major facilitator Superfamily
EJ992_RS20000	COG1414	Transcriptional regulator
EJ992_RS20010	COG0280	phosphate acetyltransferase
EJ992_RS20015	COG3253	May function as heme-dependent peroxidase
EJ992_RS20030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EJ992_RS20050	COG1131	(ABC) transporter
EJ992_RS20065	COG2363	Small membrane protein
EJ992_RS20070	COG2233	PERMEase
EJ992_RS20080	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS20085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EJ992_RS20090	COG1216	Glycosyl transferase, family 2
EJ992_RS20095	COG0351	phosphomethylpyrimidine kinase
EJ992_RS20105	COG1621	beta-fructofuranosidase activity
EJ992_RS20110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS20110	COG1263	PTS System
EJ992_RS20115	COG3711	transcriptional antiterminator
EJ992_RS20125	COG1404	Belongs to the peptidase S8 family
EJ992_RS20135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EJ992_RS20140	COG0778	Nitroreductase
EJ992_RS20145	COG1473	amidohydrolase
EJ992_RS20150	COG0772	Belongs to the SEDS family
EJ992_RS20155	COG0772	Belongs to the SEDS family
EJ992_RS20160	COG3314	Sporulation integral membrane protein YlbJ
EJ992_RS20180	COG0456	acetyltransferase
EJ992_RS20215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EJ992_RS20225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EJ992_RS20230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EJ992_RS20235	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJ992_RS20255	COG3162	membrane
EJ992_RS20260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS20265	COG1070	Carbohydrate kinase
EJ992_RS20270	COG2115	Belongs to the xylose isomerase family
EJ992_RS20280	COG0352	thiamine-phosphate diphosphorylase activity
EJ992_RS20285	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EJ992_RS20305	COG1380	Effector of murein hydrolase LrgA
EJ992_RS20310	COG1346	cytolysis
EJ992_RS20320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EJ992_RS20325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EJ992_RS20330	COG0346	lactoylglutathione lyase activity
EJ992_RS20340	COG1442	glycosyl transferase family 8
EJ992_RS20350	COG4585	Histidine kinase
EJ992_RS20355	COG2197	response regulator
EJ992_RS20360	COG2409	Drug exporters of the RND superfamily
EJ992_RS20365	COG5522	Integral membrane protein (intg_mem_TP0381)
EJ992_RS20370	COG2271	Major facilitator Superfamily
EJ992_RS20375	COG4948	Mandelate Racemase Muconate Lactonizing
EJ992_RS20380	COG0800	Aldolase
EJ992_RS20385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJ992_RS20395	COG2234	aminopeptidase activity
EJ992_RS20400	COG0477	Major facilitator Superfamily
EJ992_RS20410	COG2357	RelA SpoT domain protein
EJ992_RS20425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EJ992_RS20430	COG1696	Membrane protein involved in D-alanine export
EJ992_RS20435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EJ992_RS20440	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EJ992_RS20445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EJ992_RS20450	COG2814	Major facilitator Superfamily
EJ992_RS20455	COG1486	melibiose metabolic process
EJ992_RS20460	COG1447	Phosphotransferase system cellobiose-specific component IIA
EJ992_RS20465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS20470	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS20475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EJ992_RS20475	COG3711	transcriptional antiterminator
EJ992_RS20480	COG2094	Belongs to the DNA glycosylase MPG family
EJ992_RS20490	COG0372	Belongs to the citrate synthase family
EJ992_RS20495	COG2079	MmgE PrpD family protein
EJ992_RS20500	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EJ992_RS20515	COG1132	(ABC) transporter
EJ992_RS20520	COG2755	lipolytic protein G-D-S-L family
EJ992_RS20535	COG2814	Major facilitator Superfamily
EJ992_RS20540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EJ992_RS20545	COG1131	(ABC) transporter
EJ992_RS20565	COG1595	DNA-templated transcription, initiation
EJ992_RS20570	COG2814	Major facilitator Superfamily
EJ992_RS20575	COG0753	catalase activity
EJ992_RS20580	COG0753	catalase activity
EJ992_RS20585	COG0735	belongs to the Fur family
EJ992_RS20590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EJ992_RS20595	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EJ992_RS20600	COG1131	(ABC) transporter
EJ992_RS20615	COG1131	(ABC) transporter
EJ992_RS20670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EJ992_RS20675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EJ992_RS20680	COG4988	ABC transporter
EJ992_RS20685	COG1294	oxidase, subunit
EJ992_RS20690	COG1271	oxidase subunit
EJ992_RS20700	COG2116	formate transmembrane transporter activity
EJ992_RS20710	COG0281	malic enzyme
EJ992_RS20715	COG1757	Na H antiporter
EJ992_RS20720	COG1027	Aspartate ammonia-lyase
EJ992_RS20725	COG0252	asparaginase activity
EJ992_RS20730	COG1396	sequence-specific DNA binding
EJ992_RS20735	COG2706	6-phosphogluconolactonase activity
EJ992_RS20745	COG2205	protein histidine kinase activity
EJ992_RS20755	COG1136	(ABC) transporter
EJ992_RS20760	COG0577	efflux transmembrane transporter activity
EJ992_RS20765	COG5294	Protein conserved in bacteria
EJ992_RS20775	COG0726	polysaccharide deacetylase
EJ992_RS20790	COG1215	transferase activity, transferring glycosyl groups
EJ992_RS20795	COG3493	citrate carrier protein
EJ992_RS20800	COG0584	glycerophosphoryl diester phosphodiesterase
EJ992_RS20815	COG1368	sulfuric ester hydrolase activity
EJ992_RS20825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EJ992_RS20840	COG2235	arginine
EJ992_RS20845	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EJ992_RS20855	COG0549	Belongs to the carbamate kinase family
EJ992_RS20865	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS20870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EJ992_RS20880	COG1595	DNA-templated transcription, initiation
EJ992_RS20905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EJ992_RS20910	COG2195	Cleaves the N-terminal amino acid of tripeptides
EJ992_RS20920	COG1621	beta-fructofuranosidase activity
EJ992_RS20925	COG2223	nitrite transmembrane transporter activity
EJ992_RS20930	COG0395	ABC-type sugar transport system, permease component
EJ992_RS20935	COG1175	transmembrane transport
EJ992_RS20945	COG1609	Transcriptional regulator
EJ992_RS20960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EJ992_RS20965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJ992_RS20970	COG0463	Glycosyl transferase, family 2
EJ992_RS20975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJ992_RS21000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EJ992_RS21015	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS21020	COG2190	(PTS) system
EJ992_RS21020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS21020	COG1263	PTS System
EJ992_RS21025	COG3711	transcriptional antiterminator
EJ992_RS21030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EJ992_RS21035	COG1122	ATPase activity
EJ992_RS21040	COG4721	ABC-type cobalt transport system, permease component
EJ992_RS21045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EJ992_RS21050	COG2224	Isocitrate lyase
EJ992_RS21055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EJ992_RS21065	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EJ992_RS21070	COG0577	efflux transmembrane transporter activity
EJ992_RS21075	COG1136	(ABC) transporter
EJ992_RS21080	COG2205	protein histidine kinase activity
EJ992_RS21085	COG0745	RESPONSE REGULATOR receiver
EJ992_RS21090	COG2723	6-phospho-beta-galactosidase activity
EJ992_RS21095	COG1263	PTS System
EJ992_RS21095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS21095	COG2190	(PTS) system
EJ992_RS21105	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EJ992_RS21120	COG3507	Belongs to the glycosyl hydrolase 43 family
EJ992_RS21125	COG0513	Belongs to the DEAD box helicase family
EJ992_RS21155	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EJ992_RS21160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EJ992_RS21165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EJ992_RS21170	COG2390	Transcriptional regulator
EJ992_RS21180	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EJ992_RS21185	COG3706	GGDEF domain
EJ992_RS21190	COG5298	Protein conserved in bacteria
EJ992_RS21205	COG3977	Valine--pyruvate aminotransferase
EJ992_RS21220	COG1181	Belongs to the D-alanine--D-alanine ligase family
EJ992_RS21230	COG0191	fructose-bisphosphate aldolase activity
EJ992_RS21235	COG1082	Xylose isomerase domain protein TIM barrel
EJ992_RS21240	COG1082	Xylose isomerase domain protein TIM barrel
EJ992_RS21245	COG0673	inositol 2-dehydrogenase activity
EJ992_RS21250	COG2814	Major facilitator Superfamily
EJ992_RS21255	COG1082	Xylose isomerase domain protein TIM barrel
EJ992_RS21260	COG3962	Belongs to the TPP enzyme family
EJ992_RS21265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EJ992_RS21270	COG3718	enzyme involved in inositol metabolism
EJ992_RS21275	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS21280	COG1349	DNA-binding transcription factor activity
EJ992_RS21285	COG0667	Aldo Keto reductase
EJ992_RS21290	COG0584	glycerophosphoryl diester phosphodiesterase
EJ992_RS21295	COG2271	Major facilitator Superfamily
EJ992_RS21300	COG0326	Molecular chaperone. Has ATPase activity
EJ992_RS21305	COG0488	(ABC) transporter
EJ992_RS21310	COG0561	phosphatase activity
EJ992_RS21330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EJ992_RS21360	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EJ992_RS21365	COG0577	efflux transmembrane transporter activity
EJ992_RS21370	COG1136	(ABC) transporter
EJ992_RS21375	COG2205	protein histidine kinase activity
EJ992_RS21380	COG0745	RESPONSE REGULATOR receiver
EJ992_RS21390	COG5278	phosphoserine phosphatase activity
EJ992_RS21390	COG0840	transmembrane signaling receptor activity
EJ992_RS21395	COG1115	amino acid carrier protein
EJ992_RS21400	COG0686	Belongs to the AlaDH PNT family
EJ992_RS21405	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EJ992_RS21410	COG1874	Beta-galactosidase
EJ992_RS21415	COG3833	ABC-type maltose transport systems, permease component
EJ992_RS21420	COG1175	transmembrane transport
EJ992_RS21425	COG2182	Extracellular solute-binding protein
EJ992_RS21430	COG1609	Transcriptional regulator
EJ992_RS21440	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EJ992_RS21445	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EJ992_RS21450	COG1940	carbohydrate kinase activity
EJ992_RS21475	COG1012	belongs to the aldehyde dehydrogenase family
EJ992_RS21475	COG1454	alcohol dehydrogenase
EJ992_RS21480	COG0450	alkyl hydroperoxide reductase
EJ992_RS21485	COG3634	alkyl hydroperoxide reductase activity
EJ992_RS21510	COG1131	(ABC) transporter
EJ992_RS21515	COG0842	Transport permease protein
EJ992_RS21525	COG2197	response regulator
EJ992_RS21580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EJ992_RS21625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EJ992_RS21630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EJ992_RS21645	COG0456	acetyltransferase
EJ992_RS21660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EJ992_RS21665	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EJ992_RS21670	COG4853	Protein conserved in bacteria
EJ992_RS21675	COG4863	YycH protein
EJ992_RS21680	COG5002	protein histidine kinase activity
EJ992_RS21685	COG0745	RESPONSE REGULATOR receiver
EJ992_RS21710	COG1051	belongs to the nudix hydrolase family
EJ992_RS21715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EJ992_RS21725	COG0305	Participates in initiation and elongation during chromosome replication
EJ992_RS21740	COG3093	addiction module antidote protein HigA
EJ992_RS21745	COG2807	transmembrane transport
EJ992_RS21750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EJ992_RS21755	COG0363	glucosamine-6-phosphate deaminase activity
EJ992_RS21760	COG2188	Transcriptional regulator
EJ992_RS21765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EJ992_RS21770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EJ992_RS21770	COG1263	PTS System
EJ992_RS21775	COG0359	binds to the 23S rRNA
EJ992_RS21780	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EJ992_RS21785	COG4241	membrane
EJ992_RS21790	COG5577	PFAM Coat F domain
EJ992_RS21795	COG0589	response to stress
EJ992_RS21800	COG0659	secondary active sulfate transmembrane transporter activity
EJ992_RS21805	COG2271	Major facilitator Superfamily
EJ992_RS21810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EJ992_RS21815	COG0629	single-stranded DNA binding
EJ992_RS21820	COG0360	Binds together with S18 to 16S ribosomal RNA
EJ992_RS21825	COG0012	GTP binding
EJ992_RS21835	COG4481	Protein conserved in bacteria
EJ992_RS21840	COG3949	Membrane
EJ992_RS21850	COG1475	DNA binding
EJ992_RS21855	COG1192	Involved in chromosome partitioning
EJ992_RS21860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EJ992_RS21870	COG1475	DNA binding
EJ992_RS21875	COG0357	Ribosomal RNA small subunit methyltransferase G
EJ992_RS21880	COG0445	tRNA wobble uridine modification
EJ992_RS21885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EJ992_RS21890	COG1847	R3H domain protein
EJ992_RS21895	COG0706	membrane insertase activity
EJ992_RS21900	COG0594	ribonuclease P activity