locus-tag	class	description
JAV55_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JAV55_RS00010	COG0592	DNA-directed DNA polymerase activity
JAV55_RS00015	COG2501	S4 domain
JAV55_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JAV55_RS00030	COG0187	DNA topoisomerase II activity
JAV55_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JAV55_RS00070	COG0516	GMP reductase activity
JAV55_RS00070	COG0517	IMP dehydrogenase activity
JAV55_RS00075	COG1686	Belongs to the peptidase S11 family
JAV55_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JAV55_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JAV55_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JAV55_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
JAV55_RS00100	COG2610	gluconate transmembrane transporter activity
JAV55_RS00105	COG3835	regulator
JAV55_RS00120	COG1428	Deoxynucleoside kinase
JAV55_RS00125	COG1428	Deoxynucleoside kinase
JAV55_RS00130	COG1388	LysM domain
JAV55_RS00130	COG3858	chitin binding
JAV55_RS00135	COG1335	isochorismatase
JAV55_RS00140	COG0590	tRNA wobble adenosine to inosine editing
JAV55_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JAV55_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JAV55_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JAV55_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JAV55_RS00210	COG3853	Toxic anion resistance protein (TelA)
JAV55_RS00215	COG1982	Orn Lys Arg decarboxylase major
JAV55_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JAV55_RS00225	COG3870	Protein conserved in bacteria
JAV55_RS00230	COG1728	Protein conserved in bacteria
JAV55_RS00235	COG0470	DNA polymerase III
JAV55_RS00240	COG1774	PSP1 C-terminal conserved region
JAV55_RS00245	COG4467	Involved in initiation control of chromosome replication
JAV55_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JAV55_RS00255	COG2827	Endonuclease containing a URI domain
JAV55_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JAV55_RS00265	COG2002	toxin-antitoxin pair type II binding
JAV55_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_RS00275	COG0084	hydrolase, TatD family'
JAV55_RS00280	COG3584	3D domain protein
JAV55_RS00280	COG3583	domain protein
JAV55_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JAV55_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JAV55_RS00300	COG4466	Protein conserved in bacteria
JAV55_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JAV55_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_RS00320	COG0251	oxidation-reduction process
JAV55_RS00325	COG2088	sporulation resulting in formation of a cellular spore
JAV55_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JAV55_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JAV55_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JAV55_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
JAV55_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JAV55_RS00360	COG2002	toxin-antitoxin pair type II binding
JAV55_RS00365	COG2244	polysaccharide biosynthetic process
JAV55_RS00370	COG3956	TIGRFAM MazG family protein
JAV55_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JAV55_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JAV55_RS00395	COG1098	S1 RNA binding domain
JAV55_RS00410	COG2208	phosphoserine phosphatase activity
JAV55_RS00415	COG2304	oxidoreductase activity
JAV55_RS00420	COG0515	serine threonine protein kinase
JAV55_RS00425	COG0037	tRNA processing
JAV55_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JAV55_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JAV55_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JAV55_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JAV55_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JAV55_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_RS00460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JAV55_RS00465	COG0512	Glutamine amidotransferase of anthranilate synthase
JAV55_RS00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_RS00475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JAV55_RS00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JAV55_RS00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JAV55_RS00490	COG1396	sequence-specific DNA binding
JAV55_RS00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JAV55_RS00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JAV55_RS00580	COG4463	regulation of RNA biosynthetic process
JAV55_RS00585	COG3880	PFAM UvrB UvrC protein
JAV55_RS00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JAV55_RS00595	COG0542	response to heat
JAV55_RS00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JAV55_RS00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JAV55_RS00610	COG4956	integral membrane protein (PIN domain superfamily)
JAV55_RS00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JAV55_RS00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JAV55_RS00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JAV55_RS00630	COG1045	serine acetyltransferase
JAV55_RS00635	COG0215	cysteine-tRNA ligase activity
JAV55_RS00640	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JAV55_RS00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JAV55_RS00650	COG3688	RNA-binding protein containing a PIN domain
JAV55_RS00660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_RS00670	COG0250	Participates in transcription elongation, termination and antitermination
JAV55_RS00675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JAV55_RS00680	COG0081	regulation of translation
JAV55_RS00685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JAV55_RS00690	COG0222	ribosome binding
JAV55_RS00695	COG2813	Specifically methylates the guanine in position
JAV55_RS00700	COG0085	RNA polymerase activity
JAV55_RS00705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JAV55_RS00710	COG1358	cellular component organization or biogenesis
JAV55_RS00715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JAV55_RS00720	COG0049	tRNA binding
JAV55_RS00725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JAV55_RS00730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JAV55_RS00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JAV55_RS00745	COG0088	Forms part of the polypeptide exit tunnel
JAV55_RS00750	COG0089	rRNA binding
JAV55_RS00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JAV55_RS00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JAV55_RS00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JAV55_RS00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JAV55_RS00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JAV55_RS00780	COG0255	Belongs to the universal ribosomal protein uL29 family
JAV55_RS00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JAV55_RS00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JAV55_RS00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JAV55_RS00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JAV55_RS00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_RS00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JAV55_RS00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JAV55_RS00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JAV55_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JAV55_RS00830	COG1841	ribosomal large subunit assembly
JAV55_RS00835	COG0200	Binds to the 23S rRNA
JAV55_RS00840	COG0201	protein transport
JAV55_RS00845	COG0563	adenylate kinase activity
JAV55_RS00850	COG0024	Methionine aminopeptidase
JAV55_RS00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
JAV55_RS00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JAV55_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JAV55_RS00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JAV55_RS00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JAV55_RS00880	COG0202	RNA polymerase activity
JAV55_RS00885	COG0203	ribosomal protein L17
JAV55_RS00890	COG1122	ATPase activity
JAV55_RS00895	COG1122	ATPase activity
JAV55_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JAV55_RS00905	COG0101	tRNA pseudouridine synthase activity
JAV55_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JAV55_RS00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JAV55_RS00920	COG2318	DinB family
JAV55_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS00935	COG0489	protein tyrosine kinase activity
JAV55_RS00945	COG2194	sulfuric ester hydrolase activity
JAV55_RS00950	COG0726	polysaccharide deacetylase
JAV55_RS00980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_RS00990	COG0385	Bile acid
JAV55_RS01005	COG3876	Protein conserved in bacteria
JAV55_RS01010	COG1472	Belongs to the glycosyl hydrolase 3 family
JAV55_RS01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_RS01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS01020	COG1263	PTS System
JAV55_RS01025	COG1737	Transcriptional regulator
JAV55_RS01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JAV55_RS01035	COG1683	Conserved Protein
JAV55_RS01070	COG1595	DNA-templated transcription, initiation
JAV55_RS01075	COG5662	AntiSigma factor
JAV55_RS01080	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JAV55_RS01085	COG4856	YbbR-like protein
JAV55_RS01090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JAV55_RS01095	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JAV55_RS01115	COG1725	Transcriptional regulator
JAV55_RS01120	COG0640	Transcriptional regulator
JAV55_RS01125	COG2814	Major facilitator Superfamily
JAV55_RS01135	COG1132	(ABC) transporter
JAV55_RS01140	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JAV55_RS01165	COG1011	Hydrolase
JAV55_RS01170	COG1113	amino acid transport
JAV55_RS01175	COG2851	Citrate transporter
JAV55_RS01180	COG3181	Tripartite tricarboxylate transporter family receptor
JAV55_RS01185	COG4565	transcriptional regulatory protein
JAV55_RS01190	COG3290	protein histidine kinase activity
JAV55_RS01205	COG2211	Major facilitator Superfamily
JAV55_RS01225	COG1331	Highly conserved protein containing a thioredoxin domain
JAV55_RS01230	COG3677	Transposase
JAV55_RS01265	COG1331	Highly conserved protein containing a thioredoxin domain
JAV55_RS01270	COG0477	Major facilitator Superfamily
JAV55_RS01290	COG1283	sodium-dependent phosphate transmembrane transporter activity
JAV55_RS01295	COG4682	membrane
JAV55_RS01320	COG0697	spore germination
JAV55_RS01325	COG2207	Transcriptional regulator
JAV55_RS01325	COG1917	Cupin 2, conserved barrel domain protein
JAV55_RS01345	COG0371	Dehydrogenase
JAV55_RS01350	COG0840	transmembrane signaling receptor activity
JAV55_RS01355	COG4213	ABC transporter substrate-binding protein
JAV55_RS01370	COG4257	antibiotic catabolic process
JAV55_RS01380	COG0833	amino acid
JAV55_RS01385	COG2040	homocysteine
JAV55_RS01395	COG2190	(PTS) system
JAV55_RS01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS01395	COG1263	PTS System
JAV55_RS01400	COG0789	Transcriptional regulator
JAV55_RS01405	COG2323	membrane
JAV55_RS01410	COG4451	ribulose bisphosphate carboxylase, small
JAV55_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JAV55_RS01415	COG2205	protein histidine kinase activity
JAV55_RS01420	COG1115	amino acid carrier protein
JAV55_RS01425	COG2066	Belongs to the glutaminase family
JAV55_RS01430	COG4191	Histidine kinase
JAV55_RS01435	COG0784	Response regulator, receiver
JAV55_RS01460	COG3540	Alkaline phosphatase
JAV55_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JAV55_RS01470	COG0805	protein transport
JAV55_RS01475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_RS01480	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS01485	COG2271	Major facilitator Superfamily
JAV55_RS01490	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_RS01495	COG2186	Transcriptional regulator
JAV55_RS01500	COG2721	sulfolactate sulfo-lyase activity
JAV55_RS01505	COG0745	RESPONSE REGULATOR receiver
JAV55_RS01510	COG2205	protein histidine kinase activity
JAV55_RS01515	COG1131	(ABC) transporter
JAV55_RS01540	COG3173	Aminoglycoside phosphotransferase
JAV55_RS01545	COG1846	Transcriptional regulator
JAV55_RS01550	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS01570	COG0789	Transcriptional regulator
JAV55_RS01595	COG0697	spore germination
JAV55_RS01600	COG1714	RDD family
JAV55_RS01605	COG3012	SEC-C Motif Domain Protein
JAV55_RS01605	COG1405	negative regulation of cell septum assembly
JAV55_RS01610	COG1131	(ABC) transporter
JAV55_RS01635	COG0583	DNA-binding transcription factor activity
JAV55_RS01640	COG1942	4-Oxalocrotonate Tautomerase
JAV55_RS01660	COG1288	antiporter activity
JAV55_RS01670	COG0456	acetyltransferase
JAV55_RS01680	COG1164	Oligoendopeptidase f
JAV55_RS01685	COG2261	transglycosylase associated protein
JAV55_RS01695	COG0247	lactate metabolic process
JAV55_RS01700	COG0277	FAD linked oxidase domain protein
JAV55_RS01705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS01710	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_RS01715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS01720	COG1486	melibiose metabolic process
JAV55_RS01725	COG2188	Transcriptional regulator
JAV55_RS01730	COG3394	polysaccharide catabolic process
JAV55_RS01745	COG3591	Belongs to the peptidase S1B family
JAV55_RS01750	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS01760	COG1595	DNA-templated transcription, initiation
JAV55_RS01770	COG3773	Cell wall hydrolase
JAV55_RS01775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_RS01780	COG3883	PFAM NLP P60 protein
JAV55_RS01780	COG0791	NLP P60 protein
JAV55_RS01790	COG1131	(ABC) transporter
JAV55_RS01795	COG1309	transcriptional regulator
JAV55_RS01815	COG2310	stress, protein
JAV55_RS01820	COG2310	stress, protein
JAV55_RS01825	COG2310	stress, protein
JAV55_RS01830	COG0861	Integral membrane protein TerC family
JAV55_RS01850	COG3853	Toxic anion resistance protein (TelA)
JAV55_RS01855	COG0785	Cytochrome C biogenesis protein
JAV55_RS01865	COG0789	Transcriptional regulator
JAV55_RS01870	COG2223	nitrite transmembrane transporter activity
JAV55_RS01875	COG0039	L-malate dehydrogenase activity
JAV55_RS01880	COG1620	l-lactate permease
JAV55_RS01885	COG1280	lysine exporter protein (LysE YggA)
JAV55_RS01890	COG1113	amino acid transport
JAV55_RS01895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JAV55_RS01900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JAV55_RS01905	COG3541	Predicted nucleotidyltransferase
JAV55_RS01910	COG0506	proline dehydrogenase activity
JAV55_RS01915	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS01920	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS01925	COG2508	Transcriptional regulator
JAV55_RS01930	COG3689	TIGRFAM TIGR03943 family protein
JAV55_RS01935	COG0701	Predicted permease
JAV55_RS01940	COG3458	cephalosporin-C deacetylase activity
JAV55_RS01960	COG0765	amino acid transport
JAV55_RS01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_RS01970	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS01980	COG2723	6-phospho-beta-galactosidase activity
JAV55_RS01990	COG3209	COG3209 Rhs family protein
JAV55_RS02000	COG3266	domain, Protein
JAV55_RS02000	COG0515	serine threonine protein kinase
JAV55_RS02010	COG5444	nuclease activity
JAV55_RS02035	COG1176	ABC-type spermidine putrescine transport system, permease component I
JAV55_RS02045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_RS02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_RS02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_RS02060	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JAV55_RS02065	COG0697	spore germination
JAV55_RS02070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_RS02080	COG2819	hydrolase of the alpha beta superfamily
JAV55_RS02090	COG2364	Membrane
JAV55_RS02100	COG1131	(ABC) transporter
JAV55_RS02130	COG1126	abc transporter atp-binding protein
JAV55_RS02135	COG0765	amino acid transport
JAV55_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_RS02145	COG3829	transcription factor binding
JAV55_RS02150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JAV55_RS02155	COG0833	amino acid
JAV55_RS02160	COG0010	Belongs to the arginase family
JAV55_RS02165	COG0583	DNA-binding transcription factor activity
JAV55_RS02170	COG0163	prenyltransferase activity
JAV55_RS02175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JAV55_RS02220	COG5444	nuclease activity
JAV55_RS02240	COG2972	Histidine kinase
JAV55_RS02245	COG4753	response regulator
JAV55_RS02245	COG2207	Transcriptional regulator
JAV55_RS02250	COG4213	ABC transporter substrate-binding protein
JAV55_RS02260	COG4214	carbohydrate transport
JAV55_RS02265	COG2271	Major facilitator Superfamily
JAV55_RS02270	COG0456	acetyltransferase
JAV55_RS02270	COG1846	Transcriptional regulator
JAV55_RS02275	COG1874	Beta-galactosidase
JAV55_RS02280	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
JAV55_RS02285	COG3104	oligopeptide transport
JAV55_RS02290	COG5434	Belongs to the glycosyl hydrolase 28 family
JAV55_RS02300	COG0697	spore germination
JAV55_RS02310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JAV55_RS02320	COG1136	(ABC) transporter
JAV55_RS02325	COG0577	efflux transmembrane transporter activity
JAV55_RS02330	COG0745	RESPONSE REGULATOR receiver
JAV55_RS02335	COG3850	Histidine kinase
JAV55_RS02335	COG5002	protein histidine kinase activity
JAV55_RS02340	COG0840	transmembrane signaling receptor activity
JAV55_RS02345	COG0527	aspartate kinase activity
JAV55_RS02350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS02355	COG4605	iron ion homeostasis
JAV55_RS02360	COG4604	ABC transporter, ATP-binding protein
JAV55_RS02365	COG4607	ABC-type enterochelin transport system periplasmic component
JAV55_RS02370	COG2814	Major facilitator Superfamily
JAV55_RS02375	COG1309	transcriptional regulator
JAV55_RS02385	COG0778	Nitroreductase
JAV55_RS02390	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JAV55_RS02395	COG0640	Transcriptional regulator
JAV55_RS02400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_RS02405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JAV55_RS02410	COG0531	amino acid
JAV55_RS02415	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS02420	COG0697	spore germination
JAV55_RS02430	COG4549	nuclear export factor GLE1
JAV55_RS02435	COG2372	response to copper ion
JAV55_RS02435	COG1276	copper resistance
JAV55_RS02440	COG1349	DNA-binding transcription factor activity
JAV55_RS02445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_RS02450	COG0243	molybdopterin cofactor binding
JAV55_RS02455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_RS02460	COG2146	nitrite reductase [NAD(P)H] activity
JAV55_RS02465	COG1587	Uroporphyrinogen-III synthase
JAV55_RS02465	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JAV55_RS02470	COG1802	Transcriptional regulator
JAV55_RS02475	COG0471	metal ion transport
JAV55_RS02480	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_RS02485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_RS02495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS02510	COG3959	Transketolase, thiamine diphosphate binding domain
JAV55_RS02515	COG3958	Transketolase
JAV55_RS02520	COG0561	phosphatase activity
JAV55_RS02525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JAV55_RS02530	COG1914	H( )-stimulated, divalent metal cation uptake system
JAV55_RS02535	COG4336	lyase activity
JAV55_RS02540	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JAV55_RS02545	COG1984	allophanate hydrolase subunit 2
JAV55_RS02550	COG1414	Transcriptional regulator
JAV55_RS02555	COG2755	lipolytic protein G-D-S-L family
JAV55_RS02560	COG2213	PTS system mannitol-specific
JAV55_RS02565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS02570	COG0246	Mannitol dehydrogenase
JAV55_RS02575	COG3711	transcriptional antiterminator
JAV55_RS02580	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS02585	COG1917	Cupin 2, conserved barrel domain protein
JAV55_RS02595	COG3871	stress protein (general stress protein 26)
JAV55_RS02610	COG2814	Major facilitator Superfamily
JAV55_RS02620	COG1522	sequence-specific DNA binding
JAV55_RS02625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JAV55_RS02625	COG0551	DNA topoisomerase type I activity
JAV55_RS02630	COG0531	amino acid
JAV55_RS02635	COG0028	Belongs to the TPP enzyme family
JAV55_RS02640	COG3397	chitin binding
JAV55_RS02650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS02655	COG1914	H( )-stimulated, divalent metal cation uptake system
JAV55_RS02660	COG2261	transglycosylase associated protein
JAV55_RS02665	COG1027	Aspartate ammonia-lyase
JAV55_RS02670	COG1819	glycosyl
JAV55_RS02675	COG4876	unkown
JAV55_RS02680	COG2217	Heavy metal translocating P-type atpase
JAV55_RS02690	COG0662	Cupin 2, conserved barrel domain protein
JAV55_RS02695	COG3729	General stress protein
JAV55_RS02700	COG0628	permease
JAV55_RS02705	COG1301	dicarboxylic acid transport
JAV55_RS02710	COG1131	(ABC) transporter
JAV55_RS02715	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_RS02725	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS02740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS02745	COG1181	Belongs to the D-alanine--D-alanine ligase family
JAV55_RS02750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JAV55_RS02760	COG0513	Belongs to the DEAD box helicase family
JAV55_RS02765	COG3402	PFAM membrane-flanked domain
JAV55_RS02770	COG3428	Bacterial PH domain
JAV55_RS02775	COG0705	Rhomboid family
JAV55_RS02780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JAV55_RS02785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JAV55_RS02790	COG0864	Transcriptional regulator
JAV55_RS02795	COG2337	Toxic component of a toxin-antitoxin (TA) module
JAV55_RS02800	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_RS02805	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_RS02810	COG2172	sigma factor antagonist activity
JAV55_RS02815	COG2208	phosphoserine phosphatase activity
JAV55_RS02825	COG2172	sigma factor antagonist activity
JAV55_RS02830	COG1191	sigma factor activity
JAV55_RS02835	COG2208	phosphoserine phosphatase activity
JAV55_RS02840	COG2183	response to ionizing radiation
JAV55_RS02845	COG1309	transcriptional regulator
JAV55_RS02850	COG2409	Drug exporters of the RND superfamily
JAV55_RS02850	COG1033	growth of symbiont in host cell
JAV55_RS02860	COG3091	SprT-like family
JAV55_RS02905	COG1476	TRANSCRIPTIONal
JAV55_RS02910	COG3239	Fatty acid desaturase
JAV55_RS02915	COG1278	Cold shock
JAV55_RS02920	COG1063	alcohol dehydrogenase
JAV55_RS02925	COG2364	Membrane
JAV55_RS02930	COG1846	Transcriptional regulator
JAV55_RS02935	COG0456	acetyltransferase
JAV55_RS02940	COG2808	Putative FMN-binding domain
JAV55_RS02950	COG1733	regulation of RNA biosynthetic process
JAV55_RS02955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS02980	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
JAV55_RS02985	COG1113	amino acid transport
JAV55_RS03000	COG1595	DNA-templated transcription, initiation
JAV55_RS03010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JAV55_RS03010	COG2755	lipolytic protein G-D-S-L family
JAV55_RS03015	COG2814	Major facilitator Superfamily
JAV55_RS03020	COG0745	RESPONSE REGULATOR receiver
JAV55_RS03020	COG2972	Histidine kinase
JAV55_RS03025	COG3279	Response regulator of the LytR AlgR family
JAV55_RS03035	COG3764	Sortase (surface protein transpeptidase)
JAV55_RS03040	COG2814	Major facilitator Superfamily
JAV55_RS03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JAV55_RS03085	COG0802	atpase or kinase
JAV55_RS03090	COG1214	PFAM Peptidase M22, glycoprotease
JAV55_RS03095	COG0456	acetyltransferase
JAV55_RS03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JAV55_RS03105	COG0488	(ABC) transporter
JAV55_RS03110	COG0315	cyclic pyranopterin monophosphate synthase activity
JAV55_RS03115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JAV55_RS03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JAV55_RS03125	COG0805	protein transport
JAV55_RS03135	COG1266	CAAX protease self-immunity
JAV55_RS03140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JAV55_RS03145	COG0459	protein refolding
JAV55_RS03160	COG2720	vancomycin resistance protein
JAV55_RS03175	COG2135	peptidase activity
JAV55_RS03185	COG1309	transcriptional regulator
JAV55_RS03190	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_RS03190	COG3848	Pyruvate phosphate dikinase
JAV55_RS03200	COG3189	MarR family transcriptional regulator
JAV55_RS03205	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JAV55_RS03210	COG2272	Belongs to the type-B carboxylesterase lipase family
JAV55_RS03215	COG2814	Major facilitator Superfamily
JAV55_RS03220	COG1842	Phage shock protein A
JAV55_RS03225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JAV55_RS03230	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JAV55_RS03235	COG4260	virion core protein, lumpy skin disease virus
JAV55_RS03245	COG1378	Sugar-specific transcriptional regulator TrmB
JAV55_RS03250	COG1280	lysine exporter protein (LysE YggA)
JAV55_RS03255	COG3339	Conserved Protein
JAV55_RS03260	COG0772	Belongs to the SEDS family
JAV55_RS03265	COG0772	Belongs to the SEDS family
JAV55_RS03285	COG0726	polysaccharide deacetylase
JAV55_RS03295	COG1609	Transcriptional regulator
JAV55_RS03300	COG0366	Alpha amylase catalytic
JAV55_RS03305	COG2182	Extracellular solute-binding protein
JAV55_RS03310	COG1175	transmembrane transport
JAV55_RS03315	COG3833	ABC-type maltose transport systems, permease component
JAV55_RS03320	COG5521	maltodextrose utilization protein MalA
JAV55_RS03325	COG1554	hydrolase, family 65, central catalytic
JAV55_RS03330	COG0366	Alpha amylase catalytic
JAV55_RS03335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JAV55_RS03340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JAV55_RS03345	COG1846	Transcriptional regulator
JAV55_RS03360	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JAV55_RS03365	COG0823	Involved in the tonB-independent uptake of proteins
JAV55_RS03395	COG0702	epimerase
JAV55_RS03405	COG2132	Multicopper oxidase
JAV55_RS03420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JAV55_RS03425	COG0714	Associated with various cellular activities
JAV55_RS03430	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JAV55_RS03435	COG1305	Transglutaminase-like
JAV55_RS03440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JAV55_RS03440	COG0519	Catalyzes the synthesis of GMP from XMP
JAV55_RS03445	COG2252	PERMEase
JAV55_RS03460	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JAV55_RS03470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JAV55_RS03475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JAV55_RS03480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JAV55_RS03485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JAV55_RS03490	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JAV55_RS03495	COG0047	phosphoribosylformylglycinamidine synthase activity
JAV55_RS03500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JAV55_RS03505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JAV55_RS03510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JAV55_RS03515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JAV55_RS03520	COG0138	bifunctional purine biosynthesis protein purh
JAV55_RS03525	COG0151	Belongs to the GarS family
JAV55_RS03535	COG2124	cytochrome p450
JAV55_RS03555	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JAV55_RS03560	COG1470	cell adhesion involved in biofilm formation
JAV55_RS03565	COG4496	protein, YerC YecD
JAV55_RS03570	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JAV55_RS03575	COG0210	DNA helicase
JAV55_RS03580	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JAV55_RS03585	COG4851	CamS sex pheromone cAM373 precursor
JAV55_RS03590	COG2188	Transcriptional regulator
JAV55_RS03610	COG1735	metal-dependent hydrolase with the TIM-barrel fold
JAV55_RS03615	COG0626	cystathionine gamma-synthase activity
JAV55_RS03620	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JAV55_RS03625	COG3457	Alanine racemase
JAV55_RS03630	COG0363	glucosamine-6-phosphate deaminase activity
JAV55_RS03635	COG1285	pathogenesis
JAV55_RS03640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JAV55_RS03650	COG0154	amidase activity
JAV55_RS03655	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JAV55_RS03670	COG4124	Belongs to the glycosyl hydrolase 26 family
JAV55_RS03675	COG1309	transcriptional regulator
JAV55_RS03680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JAV55_RS03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS03695	COG1957	nucleoside hydrolase
JAV55_RS03700	COG1597	lipid kinase activity
JAV55_RS03705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JAV55_RS03725	COG2190	(PTS) system
JAV55_RS03725	COG1263	PTS System
JAV55_RS03725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS03730	COG2723	6-phospho-beta-galactosidase activity
JAV55_RS03735	COG3711	transcriptional antiterminator
JAV55_RS03740	COG0457	Tetratricopeptide repeat
JAV55_RS03755	COG0217	transcriptional regulatory protein
JAV55_RS03770	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS03775	COG0840	transmembrane signaling receptor activity
JAV55_RS03780	COG0471	metal ion transport
JAV55_RS03785	COG0488	(ABC) transporter
JAV55_RS03795	COG1469	GTP cyclohydrolase I activity
JAV55_RS03810	COG0523	cobalamin synthesis protein
JAV55_RS03815	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JAV55_RS03820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JAV55_RS03825	COG0156	8-amino-7-oxononanoate synthase activity
JAV55_RS03830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JAV55_RS03835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JAV55_RS03840	COG2124	cytochrome p450
JAV55_RS03850	COG0789	Transcriptional regulator
JAV55_RS03855	COG2814	Major facilitator Superfamily
JAV55_RS03860	COG0488	(ABC) transporter
JAV55_RS03865	COG0513	Belongs to the DEAD box helicase family
JAV55_RS03870	COG2130	NADP-dependent
JAV55_RS03885	COG0471	metal ion transport
JAV55_RS03905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS03915	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JAV55_RS03920	COG5658	integral membrane protein
JAV55_RS03925	COG0640	Transcriptional regulator
JAV55_RS03930	COG1254	Belongs to the acylphosphatase family
JAV55_RS03935	COG2258	MOSC domain
JAV55_RS03950	COG0024	Methionine aminopeptidase
JAV55_RS03955	COG1368	sulfuric ester hydrolase activity
JAV55_RS03965	COG1115	amino acid carrier protein
JAV55_RS03970	COG1263	PTS System
JAV55_RS03970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS03975	COG0366	Alpha amylase catalytic
JAV55_RS03980	COG2188	Transcriptional regulator
JAV55_RS04005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_RS04010	COG1045	serine acetyltransferase
JAV55_RS04015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_RS04025	COG1215	transferase activity, transferring glycosyl groups
JAV55_RS04030	COG0457	Tetratricopeptide repeat
JAV55_RS04030	COG0463	Glycosyl transferase, family 2
JAV55_RS04040	COG0673	inositol 2-dehydrogenase activity
JAV55_RS04050	COG0657	acetylesterase activity
JAV55_RS04055	COG1733	regulation of RNA biosynthetic process
JAV55_RS04060	COG0778	Nitroreductase
JAV55_RS04065	COG0737	Belongs to the 5'-nucleotidase family
JAV55_RS04070	COG0693	protein deglycase activity
JAV55_RS04075	COG4840	Belongs to the UPF0435 family
JAV55_RS04080	COG1115	amino acid carrier protein
JAV55_RS04085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_RS04090	COG4980	gas vesicle protein
JAV55_RS04095	COG1295	ribonuclease BN
JAV55_RS04100	COG0477	Major facilitator Superfamily
JAV55_RS04110	COG0387	Pfam Sodium calcium exchanger
JAV55_RS04120	COG0535	radical SAM domain protein
JAV55_RS04130	COG0726	polysaccharide deacetylase
JAV55_RS04135	COG0371	Dehydrogenase
JAV55_RS04145	COG0598	Magnesium transport protein CorA
JAV55_RS04150	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JAV55_RS04155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JAV55_RS04160	COG4637	Psort location Cytoplasmic, score
JAV55_RS04185	COG1819	glycosyl
JAV55_RS04195	COG0477	Major facilitator Superfamily
JAV55_RS04200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS04200	COG1263	PTS System
JAV55_RS04205	COG3711	transcriptional antiterminator
JAV55_RS04210	COG0288	reversible hydration of carbon dioxide
JAV55_RS04215	COG3002	Belongs to the UPF0753 family
JAV55_RS04220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JAV55_RS04225	COG5609	conserved protein (DUF2294)
JAV55_RS04235	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_RS04240	COG0022	dehydrogenase e1 component
JAV55_RS04245	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_RS04250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_RS04255	COG3284	Transcriptional regulator
JAV55_RS04260	COG1742	UPF0060 membrane protein
JAV55_RS04265	COG1486	melibiose metabolic process
JAV55_RS04270	COG1737	Transcriptional regulator
JAV55_RS04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS04275	COG1263	PTS System
JAV55_RS04290	COG1733	regulation of RNA biosynthetic process
JAV55_RS04295	COG2259	Doxx family
JAV55_RS04300	COG2514	catechol 2,3-dioxygenase activity
JAV55_RS04310	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_RS04315	COG1917	Cupin 2, conserved barrel domain protein
JAV55_RS04315	COG2207	Transcriptional regulator
JAV55_RS04320	COG1653	transport
JAV55_RS04325	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS04330	COG1051	belongs to the nudix hydrolase family
JAV55_RS04340	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JAV55_RS04340	COG0392	lysyltransferase activity
JAV55_RS04345	COG0384	phenazine biosynthesis protein PhzF
JAV55_RS04350	COG0778	Nitroreductase
JAV55_RS04370	COG1090	epimerase
JAV55_RS04375	COG2137	regulation of response to DNA damage stimulus
JAV55_RS04400	COG0463	Glycosyl transferase, family 2
JAV55_RS04410	COG4485	Bacterial membrane protein, YfhO
JAV55_RS04415	COG1988	membrane-bound metal-dependent
JAV55_RS04420	COG1194	a g-specific adenine glycosylase
JAV55_RS04430	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS04445	COG3557	Belongs to the UPF0374 family
JAV55_RS04450	COG1132	(ABC) transporter
JAV55_RS04455	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS04460	COG4608	Belongs to the ABC transporter superfamily
JAV55_RS04465	COG0747	negative chemotaxis
JAV55_RS04470	COG0601	transmembrane transport
JAV55_RS04475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_RS04480	COG4129	membrane
JAV55_RS04485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JAV55_RS04490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JAV55_RS04495	COG0735	belongs to the Fur family
JAV55_RS04605	COG0457	Tetratricopeptide repeat
JAV55_RS04630	COG5444	nuclease activity
JAV55_RS04635	COG0457	Tetratricopeptide repeat
JAV55_RS04640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JAV55_RS04650	COG0710	3-dehydroquinate dehydratase activity
JAV55_RS04655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JAV55_RS04660	COG1116	anion transmembrane transporter activity
JAV55_RS04665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JAV55_RS04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JAV55_RS04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_RS04685	COG1476	TRANSCRIPTIONal
JAV55_RS04695	COG1131	(ABC) transporter
JAV55_RS04715	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_RS04725	COG3382	B3 4 domain protein
JAV55_RS04730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JAV55_RS04740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JAV55_RS04745	COG0789	Transcriptional regulator
JAV55_RS04750	COG1664	Polymer-forming cytoskeletal
JAV55_RS04760	COG2766	serine protein kinase
JAV55_RS04765	COG2718	Belongs to the UPF0229 family
JAV55_RS04770	COG1566	PFAM secretion protein HlyD family protein
JAV55_RS04775	COG2814	Major facilitator Superfamily
JAV55_RS04780	COG0655	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS04790	COG1131	(ABC) transporter
JAV55_RS04795	COG1131	(ABC) transporter
JAV55_RS04800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_RS04805	COG1278	Cold shock
JAV55_RS04810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JAV55_RS04815	COG2011	ABC-type metal ion transport system permease component
JAV55_RS04820	COG1464	Belongs to the NlpA lipoprotein family
JAV55_RS04825	COG1823	symporter activity
JAV55_RS04850	COG5577	PFAM Coat F domain
JAV55_RS04855	COG5002	protein histidine kinase activity
JAV55_RS04860	COG4085	toxin activity
JAV55_RS04860	COG0737	Belongs to the 5'-nucleotidase family
JAV55_RS04860	COG1525	nuclease
JAV55_RS04865	COG3764	Sortase (surface protein transpeptidase)
JAV55_RS04870	COG0564	pseudouridine synthase activity
JAV55_RS04880	COG0517	IMP dehydrogenase activity
JAV55_RS04885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JAV55_RS04890	COG3153	acetyltransferase
JAV55_RS04890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JAV55_RS04895	COG0488	(ABC) transporter
JAV55_RS04900	COG2116	formate transmembrane transporter activity
JAV55_RS04905	COG0679	Auxin Efflux Carrier
JAV55_RS04910	COG0604	alcohol dehydrogenase
JAV55_RS04915	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JAV55_RS04920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JAV55_RS04925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JAV55_RS04930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JAV55_RS04935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JAV55_RS04950	COG2203	Gaf domain
JAV55_RS04950	COG4585	Histidine kinase
JAV55_RS04955	COG2197	response regulator
JAV55_RS04960	COG0431	NADPH-dependent FMN reductase
JAV55_RS04975	COG1959	2 iron, 2 sulfur cluster binding
JAV55_RS04980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JAV55_RS04980	COG1017	nitric oxide dioxygenase activity
JAV55_RS04985	COG2719	SpoVR family
JAV55_RS04990	COG0791	NLP P60 protein
JAV55_RS04990	COG1388	LysM domain
JAV55_RS04995	COG0583	DNA-binding transcription factor activity
JAV55_RS05000	COG0372	Belongs to the citrate synthase family
JAV55_RS05005	COG2133	pyrroloquinoline quinone binding
JAV55_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS05015	COG0733	neurotransmitter:sodium symporter activity
JAV55_RS05025	COG2207	Transcriptional regulator
JAV55_RS05025	COG3708	Transcriptional regulator
JAV55_RS05030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_RS05050	COG1595	DNA-templated transcription, initiation
JAV55_RS05055	COG0662	Cupin 2, conserved barrel domain protein
JAV55_RS05060	COG0204	Acyl-transferase
JAV55_RS05065	COG3152	Membrane
JAV55_RS05075	COG1309	transcriptional regulator
JAV55_RS05080	COG1253	flavin adenine dinucleotide binding
JAV55_RS05085	COG0789	Transcriptional regulator
JAV55_RS05090	COG1253	flavin adenine dinucleotide binding
JAV55_RS05110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JAV55_RS05115	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JAV55_RS05120	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_RS05130	COG0668	transmembrane transport
JAV55_RS05135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JAV55_RS05145	COG0726	polysaccharide deacetylase
JAV55_RS05155	COG1757	Na H antiporter
JAV55_RS05160	COG2017	converts alpha-aldose to the beta-anomer
JAV55_RS05185	COG0589	response to stress
JAV55_RS05190	COG1132	(ABC) transporter
JAV55_RS05195	COG1132	(ABC) transporter
JAV55_RS05220	COG3842	ATPase activity
JAV55_RS05225	COG2508	Transcriptional regulator
JAV55_RS05235	COG0189	ligase activity
JAV55_RS05240	COG0189	ligase activity
JAV55_RS05245	COG4399	Belongs to the UPF0754 family
JAV55_RS05250	COG3679	Belongs to the UPF0342 family
JAV55_RS05255	COG0561	phosphatase activity
JAV55_RS05260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JAV55_RS05265	COG0475	glutathione-regulated potassium exporter activity
JAV55_RS05270	COG0490	domain, Protein
JAV55_RS05280	COG1024	Enoyl-CoA hydratase
JAV55_RS05285	COG0457	Tetratricopeptide repeat
JAV55_RS05305	COG4152	abc transporter atp-binding protein
JAV55_RS05310	COG1668	transmembrane transport
JAV55_RS05315	COG0420	3'-5' exonuclease activity
JAV55_RS05320	COG4717	serine-type aminopeptidase activity
JAV55_RS05325	COG3481	metal-dependent phosphohydrolase, HD sub domain
JAV55_RS05335	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JAV55_RS05365	COG1846	Transcriptional regulator
JAV55_RS05370	COG4980	gas vesicle protein
JAV55_RS05380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JAV55_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
JAV55_RS05390	COG1131	(ABC) transporter
JAV55_RS05395	COG4473	ABC transporter
JAV55_RS05405	COG1473	amidohydrolase
JAV55_RS05410	COG3069	C4-dicarboxylate transmembrane transporter activity
JAV55_RS05415	COG2329	Antibiotic biosynthesis monooxygenase
JAV55_RS05420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_RS05425	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JAV55_RS05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JAV55_RS05435	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JAV55_RS05440	COG1309	transcriptional regulator
JAV55_RS05445	COG1511	domain protein
JAV55_RS05450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_RS05455	COG1363	Peptidase, m42
JAV55_RS05465	COG1301	dicarboxylic acid transport
JAV55_RS05475	COG1234	tRNA 3'-trailer cleavage
JAV55_RS05480	COG0095	Lipoate-protein ligase
JAV55_RS05485	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS05495	COG1396	sequence-specific DNA binding
JAV55_RS05510	COG0501	Belongs to the peptidase M48B family
JAV55_RS05520	COG0697	spore germination
JAV55_RS05525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JAV55_RS05530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS05540	COG0406	alpha-ribazole phosphatase activity
JAV55_RS05545	COG0840	transmembrane signaling receptor activity
JAV55_RS05550	COG0723	plastoquinol--plastocyanin reductase activity
JAV55_RS05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JAV55_RS05555	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS05565	COG4903	ComK protein
JAV55_RS05575	COG0398	Pfam SNARE associated Golgi protein
JAV55_RS05580	COG0681	Belongs to the peptidase S26 family
JAV55_RS05585	COG1404	Belongs to the peptidase S8 family
JAV55_RS05595	COG2508	Transcriptional regulator
JAV55_RS05605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JAV55_RS05615	COG3257	ureidoglycine aminohydrolase activity
JAV55_RS05620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JAV55_RS05625	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
JAV55_RS05630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_RS05635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_RS05645	COG0549	Belongs to the carbamate kinase family
JAV55_RS05650	COG2814	Major facilitator Superfamily
JAV55_RS05660	COG0457	Tetratricopeptide repeat
JAV55_RS05675	COG1609	Transcriptional regulator
JAV55_RS05680	COG1653	transport
JAV55_RS05685	COG1175	transmembrane transport
JAV55_RS05690	COG0395	ABC-type sugar transport system, permease component
JAV55_RS05695	COG1486	melibiose metabolic process
JAV55_RS05700	COG3180	Ammonia monooxygenase
JAV55_RS05715	COG3546	catalase activity
JAV55_RS05720	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS05725	COG0477	Major facilitator Superfamily
JAV55_RS05725	COG2814	Major facilitator Superfamily
JAV55_RS05735	COG5002	protein histidine kinase activity
JAV55_RS05740	COG0745	RESPONSE REGULATOR receiver
JAV55_RS05745	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JAV55_RS05750	COG0725	ABC transporter, periplasmic molybdate-binding protein
JAV55_RS05755	COG4149	molybdate abc transporter
JAV55_RS05760	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JAV55_RS05765	COG1074	ATP-dependent DNA helicase activity
JAV55_RS05770	COG0420	3'-5' exonuclease activity
JAV55_RS05775	COG0419	ATPase involved in DNA repair
JAV55_RS05830	COG0179	Fumarylacetoacetate (FAA) hydrolase
JAV55_RS05850	COG0367	asparagine synthase
JAV55_RS05855	COG0004	ammonium transporteR
JAV55_RS05865	COG0534	Mate efflux family protein
JAV55_RS05870	COG1917	Cupin 2, conserved barrel domain protein
JAV55_RS05870	COG2207	Transcriptional regulator
JAV55_RS05885	COG0673	inositol 2-dehydrogenase activity
JAV55_RS05905	COG1279	arginine transmembrane transporter activity
JAV55_RS05910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_RS05920	COG0076	glutamate decarboxylase activity
JAV55_RS05945	COG2153	protein acetylation
JAV55_RS05950	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS05955	COG2378	regulation of single-species biofilm formation
JAV55_RS05960	COG1410	methionine synthase
JAV55_RS05960	COG0646	methionine synthase
JAV55_RS05965	COG0646	methionine synthase
JAV55_RS05965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JAV55_RS05970	COG1666	GTP binding
JAV55_RS05975	COG2996	Protein conserved in bacteria
JAV55_RS05990	COG1307	EDD domain protein, DegV family
JAV55_RS05995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS06005	COG0516	GMP reductase activity
JAV55_RS06020	COG0561	phosphatase activity
JAV55_RS06025	COG1073	alpha beta
JAV55_RS06030	COG2151	metal-sulfur cluster biosynthetic enzyme
JAV55_RS06035	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JAV55_RS06040	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JAV55_RS06045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JAV55_RS06050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JAV55_RS06055	COG0505	Belongs to the CarA family
JAV55_RS06060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JAV55_RS06065	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JAV55_RS06070	COG1968	undecaprenyl-diphosphatase activity
JAV55_RS06085	COG2267	carboxylic ester hydrolase activity
JAV55_RS06095	COG1744	ABC transporter substrate-binding protein PnrA-like
JAV55_RS06110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_RS06115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JAV55_RS06120	COG5504	Zn-dependent protease
JAV55_RS06125	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS06130	COG4608	Belongs to the ABC transporter superfamily
JAV55_RS06140	COG0601	transmembrane transport
JAV55_RS06145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_RS06170	COG0180	Tryptophanyl-tRNA synthetase
JAV55_RS06175	COG4166	transmembrane transport
JAV55_RS06180	COG0601	transmembrane transport
JAV55_RS06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_RS06190	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS06195	COG4608	Belongs to the ABC transporter superfamily
JAV55_RS06200	COG0456	acetyltransferase
JAV55_RS06205	COG1393	Belongs to the ArsC family
JAV55_RS06210	COG0861	Integral membrane protein TerC family
JAV55_RS06220	COG4862	establishment of competence for transformation
JAV55_RS06240	COG4565	transcriptional regulatory protein
JAV55_RS06245	COG3290	protein histidine kinase activity
JAV55_RS06250	COG4469	Competence protein
JAV55_RS06255	COG1164	Oligoendopeptidase f
JAV55_RS06260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JAV55_RS06265	COG2346	COG2346, Truncated hemoglobins
JAV55_RS06270	COG0741	lytic transglycosylase activity
JAV55_RS06275	COG4116	CYTH
JAV55_RS06285	COG2357	RelA SpoT domain protein
JAV55_RS06290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JAV55_RS06295	COG0564	pseudouridine synthase activity
JAV55_RS06300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JAV55_RS06305	COG0569	domain protein
JAV55_RS06305	COG0475	glutathione-regulated potassium exporter activity
JAV55_RS06310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JAV55_RS06315	COG0352	thiamine-phosphate diphosphorylase activity
JAV55_RS06325	COG2104	thiamine diphosphate biosynthetic process
JAV55_RS06330	COG2022	thiamine diphosphate biosynthetic process
JAV55_RS06335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JAV55_RS06340	COG0351	phosphomethylpyrimidine kinase
JAV55_RS06345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JAV55_RS06400	COG0210	DNA helicase
JAV55_RS06410	COG0586	Pfam SNARE associated Golgi protein
JAV55_RS06415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_RS06420	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JAV55_RS06425	COG2246	polysaccharide biosynthetic process
JAV55_RS06430	COG2153	protein acetylation
JAV55_RS06435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JAV55_RS06440	COG2382	esterase
JAV55_RS06455	COG0626	cystathionine gamma-synthase activity
JAV55_RS06460	COG0626	cystathionine gamma-synthase activity
JAV55_RS06465	COG5505	Protein of unknown function (DUF819)
JAV55_RS06485	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_RS06490	COG0582	viral genome integration into host DNA
JAV55_RS06510	COG1476	TRANSCRIPTIONal
JAV55_RS06550	COG5377	YqaJ viral recombinase family
JAV55_RS06555	COG3723	Recombinational DNA repair protein, rece pathway
JAV55_RS06570	COG0305	Participates in initiation and elongation during chromosome replication
JAV55_RS06585	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JAV55_RS06630	COG0457	Tetratricopeptide repeat
JAV55_RS06685	COG5518	Phage portal protein
JAV55_RS06690	COG2369	cell adhesion
JAV55_RS06700	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JAV55_RS06705	COG4653	Phage capsid family
JAV55_RS06760	COG3953	SLT domain
JAV55_RS06760	COG5280	Phage tail tape measure protein TP901
JAV55_RS06760	COG3953	SLT domain
JAV55_RS06760	COG5280	Phage tail tape measure protein TP901
JAV55_RS06765	COG1652	LysM domain
JAV55_RS06770	COG4193	domain, Protein
JAV55_RS06780	COG3628	GPW Gp25 family protein
JAV55_RS06785	COG3299	homolog of phage Mu protein gp47
JAV55_RS06790	COG3778	Protein conserved in bacteria
JAV55_RS06840	COG2337	Toxic component of a toxin-antitoxin (TA) module
JAV55_RS06865	COG0110	maltose O-acetyltransferase activity
JAV55_RS06875	COG0583	DNA-binding transcription factor activity
JAV55_RS06880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JAV55_RS06885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JAV55_RS06890	COG0583	DNA-binding transcription factor activity
JAV55_RS06895	COG0697	spore germination
JAV55_RS06900	COG0346	lactoylglutathione lyase activity
JAV55_RS06910	COG3584	3D domain protein
JAV55_RS06910	COG1388	LysM domain
JAV55_RS06915	COG2814	Major facilitator Superfamily
JAV55_RS06920	COG1309	transcriptional regulator
JAV55_RS06940	COG5444	nuclease activity
JAV55_RS06945	COG4195	phage-related replication protein
JAV55_RS06950	COG2856	Zn peptidase
JAV55_RS06955	COG1396	sequence-specific DNA binding
JAV55_RS06970	COG1522	sequence-specific DNA binding
JAV55_RS06975	COG1484	DNA-dependent DNA replication
JAV55_RS06995	COG1595	DNA-templated transcription, initiation
JAV55_RS07000	COG5484	DNA packaging
JAV55_RS07000	COG3728	DNA packaging
JAV55_RS07005	COG1783	phage Terminase large subunit
JAV55_RS07010	COG5518	Phage portal protein
JAV55_RS07015	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JAV55_RS07020	COG4653	Phage capsid family
JAV55_RS07075	COG1652	LysM domain
JAV55_RS07080	COG4193	domain, Protein
JAV55_RS07090	COG3628	GPW Gp25 family protein
JAV55_RS07095	COG3299	homolog of phage Mu protein gp47
JAV55_RS07100	COG3778	Protein conserved in bacteria
JAV55_RS07135	COG1802	Transcriptional regulator
JAV55_RS07140	COG1063	alcohol dehydrogenase
JAV55_RS07145	COG1312	Catalyzes the dehydration of D-mannonate
JAV55_RS07150	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS07155	COG1063	alcohol dehydrogenase
JAV55_RS07160	COG2271	Major facilitator Superfamily
JAV55_RS07175	COG0306	phosphate transporter
JAV55_RS07180	COG1392	Phosphate transport regulator
JAV55_RS07185	COG0405	Gamma-glutamyltransferase
JAV55_RS07190	COG5578	integral membrane protein
JAV55_RS07195	COG2972	Histidine kinase
JAV55_RS07200	COG4753	response regulator
JAV55_RS07200	COG2207	Transcriptional regulator
JAV55_RS07205	COG1653	transport
JAV55_RS07210	COG1175	transmembrane transport
JAV55_RS07215	COG0395	ABC-type sugar transport system, permease component
JAV55_RS07220	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JAV55_RS07225	COG2207	Transcriptional regulator
JAV55_RS07230	COG2755	lipolytic protein G-D-S-L family
JAV55_RS07240	COG5578	integral membrane protein
JAV55_RS07245	COG3401	FG-GAP repeat protein
JAV55_RS07255	COG2755	lipolytic protein G-D-S-L family
JAV55_RS07260	COG3401	FG-GAP repeat protein
JAV55_RS07265	COG0667	Aldo Keto reductase
JAV55_RS07270	COG2755	lipolytic protein G-D-S-L family
JAV55_RS07275	COG1874	Beta-galactosidase
JAV55_RS07285	COG1653	transport
JAV55_RS07290	COG4209	transmembrane transport
JAV55_RS07295	COG0395	ABC-type sugar transport system, permease component
JAV55_RS07300	COG0531	amino acid
JAV55_RS07305	COG0346	lactoylglutathione lyase activity
JAV55_RS07315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_RS07320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_RS07325	COG2362	D-Aminopeptidase
JAV55_RS07330	COG0601	transmembrane transport
JAV55_RS07335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_RS07340	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS07345	COG4166	transmembrane transport
JAV55_RS07350	COG1619	proteins homologs of microcin C7 resistance protein MccF
JAV55_RS07355	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_RS07360	COG0791	NLP P60 protein
JAV55_RS07365	COG4608	Belongs to the ABC transporter superfamily
JAV55_RS07370	COG1834	amidinotransferase
JAV55_RS07375	COG1607	acyl-coa hydrolase
JAV55_RS07405	COG2318	DinB family
JAV55_RS07410	COG2076	Multidrug Resistance protein
JAV55_RS07415	COG2076	Multidrug Resistance protein
JAV55_RS07420	COG0788	formyltetrahydrofolate deformylase activity
JAV55_RS07425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JAV55_RS07430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JAV55_RS07435	COG1764	response to oxidative stress
JAV55_RS07440	COG1846	Transcriptional regulator
JAV55_RS07445	COG1764	response to oxidative stress
JAV55_RS07455	COG0590	tRNA wobble adenosine to inosine editing
JAV55_RS07460	COG0406	alpha-ribazole phosphatase activity
JAV55_RS07475	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JAV55_RS07480	COG1404	Belongs to the peptidase S8 family
JAV55_RS07490	COG2239	Acts as a magnesium transporter
JAV55_RS07500	COG0789	Transcriptional regulator
JAV55_RS07515	COG1846	Transcriptional regulator
JAV55_RS07520	COG1793	dna ligase
JAV55_RS07520	COG3285	dna ligase
JAV55_RS07525	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JAV55_RS07530	COG3300	MHYT domain
JAV55_RS07530	COG5001	Diguanylate cyclase
JAV55_RS07535	COG0586	Pfam SNARE associated Golgi protein
JAV55_RS07540	COG0861	Integral membrane protein TerC family
JAV55_RS07545	COG1191	sigma factor activity
JAV55_RS07565	COG0501	Belongs to the peptidase M48B family
JAV55_RS07570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_RS07575	COG0768	penicillin binding
JAV55_RS07590	COG3594	Acyltransferase
JAV55_RS07595	COG5002	protein histidine kinase activity
JAV55_RS07600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JAV55_RS07605	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JAV55_RS07610	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JAV55_RS07615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JAV55_RS07620	COG0436	Aminotransferase
JAV55_RS07625	COG1850	ribulose-bisphosphate carboxylase activity
JAV55_RS07630	COG0235	Class ii aldolase
JAV55_RS07630	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JAV55_RS07635	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JAV55_RS07640	COG0346	lactoylglutathione lyase activity
JAV55_RS07645	COG3339	Conserved Protein
JAV55_RS07655	COG3852	Histidine kinase
JAV55_RS07660	COG1846	Transcriptional regulator
JAV55_RS07665	COG1360	Flagellar Motor Protein
JAV55_RS07670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JAV55_RS07675	COG0542	response to heat
JAV55_RS07680	COG3949	Membrane
JAV55_RS07685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JAV55_RS07690	COG0720	synthase
JAV55_RS07695	COG0602	queuosine metabolic process
JAV55_RS07700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JAV55_RS07710	COG3739	integral membrane protein
JAV55_RS07715	COG3655	Transcriptional regulator
JAV55_RS07750	COG4873	Protein conserved in bacteria
JAV55_RS07760	COG3773	Cell wall hydrolase
JAV55_RS07765	COG2244	polysaccharide biosynthetic process
JAV55_RS07770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS07775	COG2217	Heavy metal translocating P-type atpase
JAV55_RS07780	COG0006	proline dipeptidase activity
JAV55_RS07790	COG1609	Transcriptional regulator
JAV55_RS07795	COG3711	transcriptional antiterminator
JAV55_RS07800	COG1263	PTS System
JAV55_RS07800	COG2190	(PTS) system
JAV55_RS07800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS07805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS07810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JAV55_RS07820	COG1533	DNA photolyase activity
JAV55_RS07825	COG0456	acetyltransferase
JAV55_RS07830	COG0840	transmembrane signaling receptor activity
JAV55_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS07840	COG2084	Dehydrogenase
JAV55_RS07845	COG2340	Cysteine-rich secretory protein family
JAV55_RS07850	COG0768	penicillin binding
JAV55_RS07855	COG4191	Histidine kinase
JAV55_RS07860	COG0436	Aminotransferase
JAV55_RS07870	COG1714	RDD family
JAV55_RS07880	COG0835	chemotaxis
JAV55_RS07880	COG0784	Response regulator, receiver
JAV55_RS07890	COG2814	Major facilitator Superfamily
JAV55_RS07895	COG1376	ErfK ybiS ycfS ynhG family protein
JAV55_RS07900	COG1408	metallophosphoesterase
JAV55_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS07910	COG2200	EAL domain
JAV55_RS07920	COG4703	Protein of unknown function (DUF1797)
JAV55_RS07930	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JAV55_RS07940	COG0517	IMP dehydrogenase activity
JAV55_RS07945	COG0583	DNA-binding transcription factor activity
JAV55_RS07950	COG0716	FMN binding
JAV55_RS07960	COG0716	FMN binding
JAV55_RS07965	COG2171	N-acyltransferase activity
JAV55_RS07970	COG1473	amidohydrolase
JAV55_RS07980	COG0450	alkyl hydroperoxide reductase
JAV55_RS07985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS08000	COG0746	molybdenum cofactor guanylyltransferase activity
JAV55_RS08005	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JAV55_RS08010	COG0303	'Molybdopterin
JAV55_RS08015	COG1763	Mo-molybdopterin cofactor biosynthetic process
JAV55_RS08020	COG0314	molybdopterin synthase activity
JAV55_RS08025	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JAV55_RS08035	COG1132	(ABC) transporter
JAV55_RS08040	COG1132	(ABC) transporter
JAV55_RS08050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JAV55_RS08055	COG1136	(ABC) transporter
JAV55_RS08060	COG0577	efflux transmembrane transporter activity
JAV55_RS08065	COG1349	DNA-binding transcription factor activity
JAV55_RS08070	COG1105	Belongs to the carbohydrate kinase PfkB family
JAV55_RS08075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS08075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS08075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS08095	COG0488	(ABC) transporter
JAV55_RS08105	COG2309	aminopeptidase activity
JAV55_RS08115	COG1077	Cell shape determining protein MreB Mrl
JAV55_RS08120	COG2002	toxin-antitoxin pair type II binding
JAV55_RS08125	COG3852	Histidine kinase
JAV55_RS08130	COG0569	domain protein
JAV55_RS08135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JAV55_RS08140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JAV55_RS08145	COG5503	Protein of unknown function (DUF1447)
JAV55_RS08150	COG0561	phosphatase activity
JAV55_RS08160	COG0242	peptide deformylase activity
JAV55_RS08170	COG0497	DNA recombination
JAV55_RS08175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_RS08180	COG0022	dehydrogenase e1 component
JAV55_RS08185	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_RS08190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_RS08195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS08205	COG1982	Orn Lys Arg decarboxylase major
JAV55_RS08210	COG4476	Belongs to the UPF0223 family
JAV55_RS08215	COG4493	Belongs to the UPF0637 family
JAV55_RS08225	COG0483	inositol monophosphate 1-phosphatase activity
JAV55_RS08245	COG1595	DNA-templated transcription, initiation
JAV55_RS08260	COG1217	gtp-binding protein TYPA
JAV55_RS08270	COG1846	Transcriptional regulator
JAV55_RS08275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JAV55_RS08280	COG4896	Protein conserved in bacteria
JAV55_RS08290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JAV55_RS08295	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JAV55_RS08300	COG2066	Belongs to the glutaminase family
JAV55_RS08305	COG4838	Belongs to the UPF0358 family
JAV55_RS08310	COG0772	Belongs to the SEDS family
JAV55_RS08315	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JAV55_RS08320	COG1612	heme a metabolic process
JAV55_RS08325	COG0109	protoheme IX farnesyltransferase activity
JAV55_RS08330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JAV55_RS08330	COG2010	Cytochrome c
JAV55_RS08335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JAV55_RS08340	COG1845	cytochrome c oxidase, subunit III
JAV55_RS08345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JAV55_RS08350	COG3336	cytochrome c oxidase
JAV55_RS08360	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JAV55_RS08365	COG2340	Cysteine-rich secretory protein family
JAV55_RS08380	COG3679	Belongs to the UPF0342 family
JAV55_RS08385	COG4471	UPF0298 protein
JAV55_RS08390	COG0742	ribosomal rna small subunit methyltransferase
JAV55_RS08395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JAV55_RS08400	COG3314	Sporulation integral membrane protein YlbJ
JAV55_RS08405	COG3480	Lon protease (S16) C-terminal proteolytic domain
JAV55_RS08410	COG1323	Belongs to the UPF0348 family
JAV55_RS08415	COG1399	metal-binding, possibly nucleic acid-binding protein
JAV55_RS08420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JAV55_RS08430	COG0454	-acetyltransferase
JAV55_RS08435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JAV55_RS08440	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JAV55_RS08445	COG2001	Belongs to the MraZ family
JAV55_RS08450	COG0275	rRNA processing
JAV55_RS08455	COG4839	cell division protein FtsL
JAV55_RS08460	COG0768	penicillin binding
JAV55_RS08465	COG0768	penicillin binding
JAV55_RS08470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JAV55_RS08475	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JAV55_RS08480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JAV55_RS08485	COG0772	Belongs to the SEDS family
JAV55_RS08490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_RS08495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JAV55_RS08500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JAV55_RS08505	COG3879	Bacterial protein of unknown function (DUF881)
JAV55_RS08510	COG3879	Bacterial protein of unknown function (DUF881)
JAV55_RS08515	COG3856	small basic protein
JAV55_RS08520	COG0849	cell division
JAV55_RS08525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JAV55_RS08530	COG4412	M6 family metalloprotease domain protein
JAV55_RS08530	COG1404	Belongs to the peptidase S8 family
JAV55_RS08535	COG1404	Belongs to the peptidase S8 family
JAV55_RS08535	COG4412	M6 family metalloprotease domain protein
JAV55_RS08545	COG1191	sigma factor activity
JAV55_RS08550	COG1191	sigma factor activity
JAV55_RS08555	COG1119	ATPase activity
JAV55_RS08560	COG0500	methyltransferase
JAV55_RS08565	COG1873	PFAM PRC-barrel domain
JAV55_RS08570	COG1496	oxidoreductase activity
JAV55_RS08575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JAV55_RS08580	COG1799	cell septum assembly
JAV55_RS08585	COG0762	integral membrane protein
JAV55_RS08590	COG2302	S4 RNA-binding domain
JAV55_RS08595	COG3599	regulation of cell shape
JAV55_RS08600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JAV55_RS08605	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_RS08610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JAV55_RS08615	COG0564	pseudouridine synthase activity
JAV55_RS08620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JAV55_RS08625	COG2233	PERMEase
JAV55_RS08630	COG0540	Belongs to the ATCase OTCase family
JAV55_RS08635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JAV55_RS08640	COG0505	Belongs to the CarA family
JAV55_RS08645	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JAV55_RS08650	COG0543	2 iron, 2 sulfur cluster binding
JAV55_RS08655	COG0167	dihydroorotate dehydrogenase activity
JAV55_RS08660	COG0284	orotidine-5'-phosphate decarboxylase activity
JAV55_RS08665	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JAV55_RS08675	COG0175	sulfate reduction
JAV55_RS08680	COG0306	phosphate transporter
JAV55_RS08685	COG2046	Belongs to the sulfate adenylyltransferase family
JAV55_RS08690	COG0529	Catalyzes the synthesis of activated sulfate
JAV55_RS08695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JAV55_RS08700	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JAV55_RS08705	COG1648	precorrin-2 dehydrogenase activity
JAV55_RS08715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JAV55_RS08720	COG1561	YicC-like family, N-terminal region
JAV55_RS08725	COG2052	Domain of unknown function (DUF370)
JAV55_RS08730	COG0194	GDP metabolic process
JAV55_RS08735	COG1758	RNA polymerase activity
JAV55_RS08740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JAV55_RS08745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JAV55_RS08750	COG0242	peptide deformylase activity
JAV55_RS08755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JAV55_RS08760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JAV55_RS08760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JAV55_RS08765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JAV55_RS08770	COG0631	protein serine/threonine phosphatase activity
JAV55_RS08775	COG0515	serine threonine protein kinase
JAV55_RS08775	COG2815	serine threonine protein kinase
JAV55_RS08780	COG1162	GTPase activity
JAV55_RS08785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JAV55_RS08790	COG1564	THIamine pyrophosphokinase
JAV55_RS08800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JAV55_RS08805	COG1302	Protein conserved in bacteria
JAV55_RS08810	COG1461	Dihydroxyacetone kinase
JAV55_RS08815	COG1760	l-serine dehydratase
JAV55_RS08820	COG1760	l-serine dehydratase
JAV55_RS08825	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JAV55_RS08830	COG1349	DNA-binding transcription factor activity
JAV55_RS08835	COG0416	fatty acid biosynthetic process
JAV55_RS08840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JAV55_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS08850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JAV55_RS08855	COG0571	ribonuclease III activity
JAV55_RS08860	COG1196	nuclear chromosome segregation
JAV55_RS08865	COG0552	protein localization to endoplasmic reticulum
JAV55_RS08870	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JAV55_RS08875	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JAV55_RS08880	COG0228	four-way junction DNA binding
JAV55_RS08885	COG1837	Belongs to the UPF0109 family
JAV55_RS08895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JAV55_RS08900	COG0336	Belongs to the RNA methyltransferase TrmD family
JAV55_RS08905	COG0335	large ribosomal subunit rRNA binding
JAV55_RS08910	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JAV55_RS08915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JAV55_RS08925	COG2257	FlhB HrpN YscU SpaS Family
JAV55_RS08930	COG0045	succinate-CoA ligase (ADP-forming) activity
JAV55_RS08935	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JAV55_RS08940	COG0758	DNA mediated transformation
JAV55_RS08945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JAV55_RS08950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JAV55_RS08955	COG4974	Belongs to the 'phage' integrase family
JAV55_RS08960	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JAV55_RS08965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JAV55_RS08970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JAV55_RS08975	COG1815	bacterial-type flagellum-dependent cell motility
JAV55_RS08980	COG1558	bacterial-type flagellum-dependent cell motility
JAV55_RS08985	COG1677	Flagellar hook-basal body complex protein FliE
JAV55_RS08990	COG1766	The M ring may be actively involved in energy transduction
JAV55_RS08995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_RS09000	COG1317	bacterial-type flagellum organization
JAV55_RS09005	COG1157	protein secretion by the type III secretion system
JAV55_RS09010	COG2882	bacterial-type flagellum organization
JAV55_RS09020	COG3144	bacterial-type flagellum assembly
JAV55_RS09025	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JAV55_RS09030	COG4786	Flagellar basal body rod
JAV55_RS09035	COG1582	Flagellar protein (FlbD)
JAV55_RS09040	COG1580	Controls the rotational direction of flagella during chemotaxis
JAV55_RS09045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_RS09050	COG1776	CheC inhibitor of MCP methylation
JAV55_RS09050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JAV55_RS09055	COG2201	protein-glutamate methylesterase activity
JAV55_RS09060	COG3190	flagellar
JAV55_RS09065	COG1338	Plays a role in the flagellum-specific transport system
JAV55_RS09070	COG1987	bacterial-type flagellum assembly
JAV55_RS09075	COG1684	flagellar biosynthetic protein fliR
JAV55_RS09080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JAV55_RS09085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JAV55_RS09090	COG1419	protein localization to endoplasmic reticulum
JAV55_RS09095	COG0455	bacterial-type flagellum organization
JAV55_RS09100	COG2201	protein-glutamate methylesterase activity
JAV55_RS09105	COG0643	Histidine kinase
JAV55_RS09105	COG2198	Histidine kinase
JAV55_RS09110	COG0835	chemotaxis
JAV55_RS09115	COG1776	CheC inhibitor of MCP methylation
JAV55_RS09120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JAV55_RS09125	COG1191	sigma factor activity
JAV55_RS09135	COG0052	Belongs to the universal ribosomal protein uS2 family
JAV55_RS09140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JAV55_RS09145	COG0528	UMP kinase activity
JAV55_RS09150	COG0233	cytoplasmic translational termination
JAV55_RS09155	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JAV55_RS09160	COG4589	Belongs to the CDS family
JAV55_RS09165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JAV55_RS09170	COG0750	zinc metalloprotease
JAV55_RS09175	COG0442	prolyl-tRNA aminoacylation
JAV55_RS09180	COG2176	DNA-directed DNA polymerase activity
JAV55_RS09205	COG0779	Required for maturation of 30S ribosomal subunits
JAV55_RS09210	COG0195	Participates in both transcription termination and antitermination
JAV55_RS09215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JAV55_RS09220	COG1358	cellular component organization or biogenesis
JAV55_RS09225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JAV55_RS09230	COG1550	Protein conserved in bacteria
JAV55_RS09235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JAV55_RS09240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JAV55_RS09245	COG0196	riboflavin kinase activity
JAV55_RS09250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JAV55_RS09255	COG1185	polyribonucleotide nucleotidyltransferase activity
JAV55_RS09260	COG0726	polysaccharide deacetylase
JAV55_RS09265	COG0612	Peptidase, M16
JAV55_RS09270	COG1873	PFAM PRC-barrel domain
JAV55_RS09275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_RS09280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JAV55_RS09285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JAV55_RS09290	COG0527	aspartate kinase activity
JAV55_RS09300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JAV55_RS09305	COG0740	serine-type endopeptidase activity
JAV55_RS09315	COG1674	ftsk spoiiie
JAV55_RS09315	COG4980	gas vesicle protein
JAV55_RS09320	COG2188	Transcriptional regulator
JAV55_RS09325	COG2814	Major facilitator Superfamily
JAV55_RS09330	COG0612	Peptidase, M16
JAV55_RS09335	COG0612	Peptidase, M16
JAV55_RS09340	COG0300	oxidoreductase activity
JAV55_RS09355	COG1426	Protein conserved in bacteria
JAV55_RS09360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JAV55_RS09365	COG1058	Belongs to the CinA family
JAV55_RS09365	COG1546	Belongs to the CinA family
JAV55_RS09375	COG1418	mRNA catabolic process
JAV55_RS09380	COG1692	metallophosphoesterase
JAV55_RS09385	COG2359	stage V sporulation protein S
JAV55_RS09395	COG1063	alcohol dehydrogenase
JAV55_RS09400	COG0156	8-amino-7-oxononanoate synthase activity
JAV55_RS09405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JAV55_RS09410	COG4550	Control of competence regulator ComK, YlbF/YmcA
JAV55_RS09420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JAV55_RS09425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JAV55_RS09430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JAV55_RS09435	COG5444	nuclease activity
JAV55_RS09450	COG0523	cobalamin synthesis protein
JAV55_RS09460	COG1247	-acetyltransferase
JAV55_RS09480	COG3619	membrane
JAV55_RS09485	COG3263	regulation of cellular component size
JAV55_RS09505	COG0393	Putative heavy-metal-binding
JAV55_RS09510	COG0398	Pfam SNARE associated Golgi protein
JAV55_RS09515	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JAV55_RS09520	COG1819	glycosyl
JAV55_RS09525	COG0531	amino acid
JAV55_RS09530	COG5577	PFAM Coat F domain
JAV55_RS09540	COG1388	LysM domain
JAV55_RS09540	COG3858	chitin binding
JAV55_RS09545	COG1309	transcriptional regulator
JAV55_RS09550	COG3631	Ketosteroid isomerase-related protein
JAV55_RS09555	COG0702	epimerase
JAV55_RS09565	COG1764	response to oxidative stress
JAV55_RS09570	COG2076	Multidrug Resistance protein
JAV55_RS09575	COG2076	Multidrug Resistance protein
JAV55_RS09590	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JAV55_RS09595	COG1923	regulation of RNA biosynthetic process
JAV55_RS09605	COG1780	Probably involved in ribonucleotide reductase function
JAV55_RS09610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JAV55_RS09615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JAV55_RS09620	COG4112	unkown
JAV55_RS09635	COG0735	belongs to the Fur family
JAV55_RS09640	COG1802	Transcriptional regulator
JAV55_RS09645	COG0697	spore germination
JAV55_RS09675	COG1309	transcriptional regulator
JAV55_RS09720	COG0464	growth
JAV55_RS09725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JAV55_RS09730	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JAV55_RS09735	COG0789	Transcriptional regulator
JAV55_RS09740	COG0174	glutamine synthetase
JAV55_RS09775	COG1073	alpha beta
JAV55_RS09820	COG1309	transcriptional regulator
JAV55_RS09825	COG2076	Multidrug Resistance protein
JAV55_RS09830	COG2076	Multidrug Resistance protein
JAV55_RS09835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS09855	COG3546	catalase activity
JAV55_RS09880	COG1846	Transcriptional regulator
JAV55_RS09885	COG0778	Nitroreductase
JAV55_RS09890	COG0346	lactoylglutathione lyase activity
JAV55_RS09895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JAV55_RS09900	COG0655	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS09925	COG3209	COG3209 Rhs family protein
JAV55_RS09930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JAV55_RS09935	COG1388	LysM domain
JAV55_RS09940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JAV55_RS09945	COG4224	UPF0291 protein
JAV55_RS09950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JAV55_RS09960	COG3763	UPF0154 protein
JAV55_RS09970	COG0785	Cytochrome C biogenesis protein
JAV55_RS09975	COG2201	protein-glutamate methylesterase activity
JAV55_RS09980	COG4846	Membrane protein involved in cytochrome C biogenesis
JAV55_RS09990	COG0071	Belongs to the small heat shock protein (HSP20) family
JAV55_RS10005	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JAV55_RS10010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS10030	COG0824	Thioesterase
JAV55_RS10055	COG4841	protein insertion into membrane
JAV55_RS10060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JAV55_RS10065	COG1832	CoA-binding protein
JAV55_RS10070	COG0187	DNA topoisomerase II activity
JAV55_RS10075	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JAV55_RS10080	COG1609	Transcriptional regulator
JAV55_RS10095	COG2160	L-arabinose isomerase activity
JAV55_RS10115	COG1115	amino acid carrier protein
JAV55_RS10125	COG2181	nitrate reductase activity
JAV55_RS10130	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JAV55_RS10135	COG1140	nitrate reductase beta subunit
JAV55_RS10140	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JAV55_RS10155	COG0535	radical SAM domain protein
JAV55_RS10160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JAV55_RS10170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JAV55_RS10175	COG2223	nitrite transmembrane transporter activity
JAV55_RS10195	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
JAV55_RS10205	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JAV55_RS10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS10230	COG3420	alginic acid biosynthetic process
JAV55_RS10235	COG1114	Component of the transport system for branched-chain amino acids
JAV55_RS10245	COG0789	Transcriptional regulator
JAV55_RS10270	COG1024	Enoyl-CoA hydratase
JAV55_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS10280	COG2084	Dehydrogenase
JAV55_RS10285	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS10290	COG1482	cell wall glycoprotein biosynthetic process
JAV55_RS10295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS10295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS10295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS10315	COG3711	transcriptional antiterminator
JAV55_RS10315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS10330	COG1725	Transcriptional regulator
JAV55_RS10335	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS10340	COG1312	Catalyzes the dehydration of D-mannonate
JAV55_RS10355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JAV55_RS10365	COG1609	Transcriptional regulator
JAV55_RS10370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_RS10375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JAV55_RS10380	COG0640	Transcriptional regulator
JAV55_RS10385	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
JAV55_RS10400	COG1649	PFAM Uncharacterised BCR, COG1649
JAV55_RS10405	COG2404	hydrolase activity, acting on ester bonds
JAV55_RS10410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JAV55_RS10420	COG2027	D-alanyl-D-alanine carboxypeptidase
JAV55_RS10425	COG1252	NADH dehydrogenase
JAV55_RS10435	COG0166	Belongs to the GPI family
JAV55_RS10445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_RS10450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JAV55_RS10455	COG1024	Enoyl-CoA hydratase
JAV55_RS10460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JAV55_RS10465	COG0511	ligase activity, forming carbon-carbon bonds
JAV55_RS10470	COG0439	Biotin carboxylase
JAV55_RS10475	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS10480	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS10485	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS10490	COG1733	regulation of RNA biosynthetic process
JAV55_RS10495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JAV55_RS10500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JAV55_RS10510	COG2323	membrane
JAV55_RS10520	COG0306	phosphate transporter
JAV55_RS10525	COG0175	sulfate reduction
JAV55_RS10530	COG1809	phosphosulfolactate synthase activity
JAV55_RS10535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS10540	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_RS10545	COG2814	Major facilitator Superfamily
JAV55_RS10550	COG0463	Glycosyl transferase, family 2
JAV55_RS10560	COG0493	'glutamate synthase
JAV55_RS10565	COG0070	glutamate synthase
JAV55_RS10565	COG0067	glutamate synthase
JAV55_RS10565	COG0069	glutamate synthase activity
JAV55_RS10570	COG0583	DNA-binding transcription factor activity
JAV55_RS10590	COG1846	Transcriptional regulator
JAV55_RS10600	COG1132	(ABC) transporter
JAV55_RS10610	COG0300	oxidoreductase activity
JAV55_RS10615	COG3848	Pyruvate phosphate dikinase
JAV55_RS10615	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_RS10620	COG0477	Major facilitator Superfamily
JAV55_RS10625	COG0243	molybdopterin cofactor binding
JAV55_RS10630	COG1846	Transcriptional regulator
JAV55_RS10640	COG0531	amino acid
JAV55_RS10650	COG0531	amino acid
JAV55_RS10655	COG0531	amino acid
JAV55_RS10660	COG0697	spore germination
JAV55_RS10665	COG0488	(ABC) transporter
JAV55_RS10670	COG0840	transmembrane signaling receptor activity
JAV55_RS10675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_RS10680	COG1404	Belongs to the peptidase S8 family
JAV55_RS10690	COG1309	transcriptional regulator
JAV55_RS10695	COG1846	Transcriptional regulator
JAV55_RS10725	COG1309	transcriptional regulator
JAV55_RS10735	COG3708	Transcriptional regulator
JAV55_RS10745	COG2378	regulation of single-species biofilm formation
JAV55_RS10755	COG0640	Transcriptional regulator
JAV55_RS10760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS10770	COG0531	amino acid
JAV55_RS10775	COG0741	lytic transglycosylase activity
JAV55_RS10780	COG1086	Polysaccharide biosynthesis protein
JAV55_RS10800	COG2322	membrane
JAV55_RS10815	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS10820	COG1388	LysM domain
JAV55_RS10820	COG3584	3D domain protein
JAV55_RS10825	COG0514	ATP-dependent DNA helicase (RecQ)
JAV55_RS10860	COG2427	Protein of unknown function (DUF1641)
JAV55_RS10865	COG3383	formate dehydrogenase (NAD+) activity
JAV55_RS10880	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JAV55_RS10920	COG0402	S-adenosylhomocysteine deaminase activity
JAV55_RS10935	COG2267	carboxylic ester hydrolase activity
JAV55_RS10950	COG1280	lysine exporter protein (LysE YggA)
JAV55_RS10955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JAV55_RS10965	COG0574	Belongs to the PEP-utilizing enzyme family
JAV55_RS10965	COG3848	Pyruvate phosphate dikinase
JAV55_RS10970	COG1309	transcriptional regulator
JAV55_RS10985	COG2318	DinB family
JAV55_RS10990	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JAV55_RS10995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_RS11010	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS11015	COG2814	Major facilitator Superfamily
JAV55_RS11030	COG1657	PFAM Prenyltransferase squalene oxidase
JAV55_RS11035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JAV55_RS11045	COG0733	neurotransmitter:sodium symporter activity
JAV55_RS11050	COG0385	Bile acid
JAV55_RS11055	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_RS11060	COG0567	Dehydrogenase, E1 component
JAV55_RS11065	COG4548	von Willebrand factor, type A
JAV55_RS11070	COG0714	Associated with various cellular activities
JAV55_RS11075	COG2032	superoxide dismutase activity
JAV55_RS11080	COG1388	LysM domain
JAV55_RS11080	COG0791	NLP P60 protein
JAV55_RS11085	COG0534	Mate efflux family protein
JAV55_RS11090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_RS11095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_RS11105	COG2962	Rard protein
JAV55_RS11115	COG4305	rare lipoprotein A
JAV55_RS11130	COG1733	regulation of RNA biosynthetic process
JAV55_RS11135	COG0778	Nitroreductase
JAV55_RS11140	COG0400	carboxylic ester hydrolase activity
JAV55_RS11150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS11155	COG0793	Belongs to the peptidase S41A family
JAV55_RS11155	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_RS11160	COG2226	methyltransferase
JAV55_RS11170	COG1876	peptidase activity
JAV55_RS11175	COG0813	purine-nucleoside phosphorylase activity
JAV55_RS11180	COG0701	Predicted permease
JAV55_RS11200	COG0671	phosphoesterase, PA-phosphatase related
JAV55_RS11215	COG4479	Belongs to the UPF0346 family
JAV55_RS11225	COG1509	lysine 2,3-aminomutase activity
JAV55_RS11230	COG0456	acetyltransferase
JAV55_RS11235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_RS11240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JAV55_RS11245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JAV55_RS11250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JAV55_RS11265	COG0456	acetyltransferase
JAV55_RS11270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JAV55_RS11275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JAV55_RS11280	COG1846	Transcriptional regulator
JAV55_RS11290	COG3706	GGDEF domain
JAV55_RS11295	COG0534	Mate efflux family protein
JAV55_RS11310	COG4698	Protein conserved in bacteria
JAV55_RS11315	COG2755	lipolytic protein G-D-S-L family
JAV55_RS11320	COG1999	signal sequence binding
JAV55_RS11335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JAV55_RS11340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JAV55_RS11345	COG1272	protein, Hemolysin III
JAV55_RS11350	COG0204	Acyl-transferase
JAV55_RS11355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JAV55_RS11360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JAV55_RS11370	COG2521	methyltransferase
JAV55_RS11370	COG2136	Putative SAM-dependent methyltransferase
JAV55_RS11380	COG0129	dihydroxy-acid dehydratase activity
JAV55_RS11385	COG1413	lyase activity
JAV55_RS11390	COG1418	mRNA catabolic process
JAV55_RS11395	COG0386	Belongs to the glutathione peroxidase family
JAV55_RS11400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JAV55_RS11405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JAV55_RS11410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_RS11420	COG1278	Cold shock
JAV55_RS11440	COG0328	RNA-DNA hybrid ribonuclease activity
JAV55_RS11445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JAV55_RS11450	COG0328	RNA-DNA hybrid ribonuclease activity
JAV55_RS11460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_RS11475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JAV55_RS11485	COG1755	Isoprenylcysteine carboxyl methyltransferase
JAV55_RS11490	COG3424	synthase
JAV55_RS11495	COG0456	acetyltransferase
JAV55_RS11500	COG2233	PERMEase
JAV55_RS11505	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_RS11510	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JAV55_RS11515	COG1199	ATP-dependent helicase activity
JAV55_RS11530	COG0116	Belongs to the methyltransferase superfamily
JAV55_RS11540	COG3599	regulation of cell shape
JAV55_RS11545	COG4474	Belongs to the UPF0398 family
JAV55_RS11555	COG3359	exonuclease
JAV55_RS11560	COG1111	helicase
JAV55_RS11560	COG1205	dead DEAH box helicase
JAV55_RS11565	COG2190	(PTS) system
JAV55_RS11570	COG0071	Belongs to the small heat shock protein (HSP20) family
JAV55_RS11605	COG3331	DNA recombination
JAV55_RS11610	COG4499	WXG100 protein secretion system (Wss), protein YukC
JAV55_RS11610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_RS11620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JAV55_RS11625	COG3935	DnaD domain protein
JAV55_RS11630	COG0017	Asparaginyl-tRNA synthetase
JAV55_RS11635	COG0436	Aminotransferase
JAV55_RS11640	COG5353	protein conserved in bacteria
JAV55_RS11650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JAV55_RS11650	COG1199	ATP-dependent helicase activity
JAV55_RS11655	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JAV55_RS11660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JAV55_RS11665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JAV55_RS11675	COG0617	tRNA 3'-terminal CCA addition
JAV55_RS11680	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS11685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JAV55_RS11690	COG1803	Methylglyoxal synthase
JAV55_RS11695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JAV55_RS11700	COG1694	Mazg nucleotide pyrophosphohydrolase
JAV55_RS11705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS11715	COG4347	Protein of unknown function (DUF1405)
JAV55_RS11725	COG2010	Cytochrome c
JAV55_RS11725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JAV55_RS11730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JAV55_RS11735	COG0723	plastoquinol--plastocyanin reductase activity
JAV55_RS11745	COG5582	Belongs to the UPF0302 family
JAV55_RS11750	COG0457	Tetratricopeptide repeat
JAV55_RS11755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JAV55_RS11760	COG0287	Prephenate dehydrogenase
JAV55_RS11765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JAV55_RS11770	COG0159	tryptophan synthase activity
JAV55_RS11775	COG0133	tryptophan synthase activity
JAV55_RS11780	COG0135	phosphoribosylanthranilate isomerase activity
JAV55_RS11785	COG0134	indole-3-glycerol-phosphate synthase activity
JAV55_RS11790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_RS11795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JAV55_RS11800	COG4401	Chorismate mutase type I
JAV55_RS11805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JAV55_RS11810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JAV55_RS11815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JAV55_RS11820	COG0105	UTP biosynthetic process
JAV55_RS11825	COG0142	geranyltranstransferase activity
JAV55_RS11830	COG2226	methyltransferase
JAV55_RS11835	COG0142	geranyltranstransferase activity
JAV55_RS11850	COG0776	regulation of translation
JAV55_RS11855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JAV55_RS11870	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JAV55_RS11875	COG1160	GTP binding
JAV55_RS11900	COG1304	FMN binding
JAV55_RS11905	COG0539	negative regulation of cytoplasmic translation
JAV55_RS11910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JAV55_RS11920	COG2959	enzyme of heme biosynthesis
JAV55_RS11925	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_RS11925	COG3773	Cell wall hydrolase
JAV55_RS11930	COG2339	peptidase activity
JAV55_RS11940	COG0492	ferredoxin-NADP+ reductase activity
JAV55_RS11945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JAV55_RS11980	COG4955	Helix-turn-helix domain
JAV55_RS11985	COG1141	Ferredoxin
JAV55_RS11990	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JAV55_RS12000	COG0739	heme binding
JAV55_RS12010	COG1595	DNA-templated transcription, initiation
JAV55_RS12030	COG5002	protein histidine kinase activity
JAV55_RS12035	COG0745	RESPONSE REGULATOR receiver
JAV55_RS12040	COG5002	protein histidine kinase activity
JAV55_RS12045	COG0745	RESPONSE REGULATOR receiver
JAV55_RS12050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JAV55_RS12055	COG1333	cytochrome c biogenesis protein
JAV55_RS12060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS12065	COG1187	pseudouridine synthase activity
JAV55_RS12070	COG0700	Nucleoside recognition
JAV55_RS12075	COG2715	membrane protein required for spore maturation
JAV55_RS12080	COG1686	Belongs to the peptidase S11 family
JAV55_RS12090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JAV55_RS12095	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JAV55_RS12105	COG1547	Domain of unknown function (DUF309)
JAV55_RS12110	COG0456	acetyltransferase
JAV55_RS12115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JAV55_RS12120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JAV55_RS12120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JAV55_RS12125	COG0307	riboflavin synthase, alpha
JAV55_RS12130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JAV55_RS12130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JAV55_RS12155	COG0457	Tetratricopeptide repeat
JAV55_RS12160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JAV55_RS12165	COG4086	secreted protein
JAV55_RS12170	COG4195	phage-related replication protein
JAV55_RS12175	COG0019	diaminopimelate decarboxylase activity
JAV55_RS12190	COG0697	spore germination
JAV55_RS12205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JAV55_RS12240	COG1686	Belongs to the peptidase S11 family
JAV55_RS12245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JAV55_RS12250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JAV55_RS12255	COG4974	Belongs to the 'phage' integrase family
JAV55_RS12265	COG0735	belongs to the Fur family
JAV55_RS12270	COG1300	Membrane
JAV55_RS12275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS12295	COG2153	protein acetylation
JAV55_RS12300	COG1379	DNA repair
JAV55_RS12305	COG0494	nUDIX hydrolase
JAV55_RS12315	COG1309	transcriptional regulator
JAV55_RS12325	COG0667	Aldo Keto reductase
JAV55_RS12335	COG1073	alpha beta
JAV55_RS12345	COG4918	Iron-sulphur cluster biosynthesis
JAV55_RS12360	COG2329	Antibiotic biosynthesis monooxygenase
JAV55_RS12365	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JAV55_RS12375	COG0747	negative chemotaxis
JAV55_RS12380	COG0601	transmembrane transport
JAV55_RS12390	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS12400	COG0534	Mate efflux family protein
JAV55_RS12415	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JAV55_RS12425	COG2211	Major facilitator Superfamily
JAV55_RS12430	COG0346	lactoylglutathione lyase activity
JAV55_RS12435	COG1072	(Pantothenic acid kinase))
JAV55_RS12445	COG1131	(ABC) transporter
JAV55_RS12465	COG4195	phage-related replication protein
JAV55_RS12470	COG0300	oxidoreductase activity
JAV55_RS12475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS12480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_RS12485	COG4187	Peptidase family M20/M25/M40
JAV55_RS12490	COG1902	pentaerythritol trinitrate reductase activity
JAV55_RS12495	COG0596	Alpha beta hydrolase
JAV55_RS12500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_RS12505	COG1234	tRNA 3'-trailer cleavage
JAV55_RS12510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JAV55_RS12525	COG2358	TRAP transporter, solute receptor (TAXI family
JAV55_RS12530	COG2188	Transcriptional regulator
JAV55_RS12535	COG2723	6-phospho-beta-galactosidase activity
JAV55_RS12540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS12545	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_RS12550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS12555	COG1785	Belongs to the alkaline phosphatase family
JAV55_RS12560	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS12565	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JAV55_RS12570	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JAV55_RS12580	COG0706	membrane insertase activity
JAV55_RS12585	COG2195	Cleaves the N-terminal amino acid of tripeptides
JAV55_RS12590	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JAV55_RS12600	COG4129	membrane
JAV55_RS12605	COG1126	abc transporter atp-binding protein
JAV55_RS12610	COG0765	amino acid transport
JAV55_RS12615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JAV55_RS12630	COG1597	lipid kinase activity
JAV55_RS12635	COG0508	dehydrogenase complex catalyzes the overall conversion of
JAV55_RS12640	COG0022	dehydrogenase e1 component
JAV55_RS12645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JAV55_RS12650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JAV55_RS12655	COG3426	butyrate kinase activity
JAV55_RS12665	COG0280	phosphate acetyltransferase
JAV55_RS12670	COG3829	transcription factor binding
JAV55_RS12670	COG3290	protein histidine kinase activity
JAV55_RS12680	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_RS12685	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS12700	COG1045	serine acetyltransferase
JAV55_RS12710	COG0745	RESPONSE REGULATOR receiver
JAV55_RS12715	COG0750	zinc metalloprotease
JAV55_RS12720	COG0497	DNA recombination
JAV55_RS12725	COG1438	arginine binding
JAV55_RS12730	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JAV55_RS12735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JAV55_RS12740	COG0142	geranyltranstransferase activity
JAV55_RS12745	COG1722	exodeoxyribonuclease VII activity
JAV55_RS12750	COG1570	exodeoxyribonuclease VII activity
JAV55_RS12755	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JAV55_RS12760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JAV55_RS12765	COG1302	Protein conserved in bacteria
JAV55_RS12770	COG0439	Biotin carboxylase
JAV55_RS12775	COG0511	ligase activity, forming carbon-carbon bonds
JAV55_RS12815	COG3854	ATPases associated with a variety of cellular activities
JAV55_RS12825	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JAV55_RS12830	COG0006	proline dipeptidase activity
JAV55_RS12835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JAV55_RS12845	COG3872	metal-dependent enzyme
JAV55_RS12855	COG1752	Esterase of the alpha-beta hydrolase superfamily
JAV55_RS12860	COG1321	iron dependent repressor
JAV55_RS12865	COG0095	Lipoate-protein ligase
JAV55_RS12870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_RS12875	COG2113	Glycine betaine
JAV55_RS12880	COG4176	ABC-type proline glycine betaine transport system permease component
JAV55_RS12885	COG0517	IMP dehydrogenase activity
JAV55_RS12885	COG4175	Glycine betaine
JAV55_RS12890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JAV55_RS12895	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JAV55_RS12900	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JAV55_RS12905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JAV55_RS12930	COG0681	Belongs to the peptidase S26 family
JAV55_RS12955	COG4940	Competence protein ComGF
JAV55_RS12965	COG4970	Tfp pilus assembly protein FimT
JAV55_RS12970	COG4537	Required for transformation and DNA binding
JAV55_RS12975	COG1459	type II secretion system
JAV55_RS12980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JAV55_RS12985	COG1366	Belongs to the anti-sigma-factor antagonist family
JAV55_RS12995	COG1393	Belongs to the ArsC family
JAV55_RS13005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS13015	COG0011	TIGRFAM Protein of
JAV55_RS13025	COG2866	Carboxypeptidase
JAV55_RS13030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS13040	COG1368	sulfuric ester hydrolase activity
JAV55_RS13045	COG1940	carbohydrate kinase activity
JAV55_RS13050	COG4483	Protein conserved in bacteria
JAV55_RS13055	COG0697	spore germination
JAV55_RS13060	COG0457	Tetratricopeptide repeat
JAV55_RS13060	COG0705	Rhomboid family
JAV55_RS13070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JAV55_RS13075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JAV55_RS13080	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS13095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JAV55_RS13100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JAV55_RS13105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JAV55_RS13110	COG0581	inorganic phosphate transmembrane transporter activity
JAV55_RS13115	COG0573	inorganic phosphate transmembrane transporter activity
JAV55_RS13120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JAV55_RS13125	COG0768	penicillin binding
JAV55_RS13130	COG0477	Major facilitator Superfamily
JAV55_RS13135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JAV55_RS13140	COG2839	Protein conserved in bacteria
JAV55_RS13145	COG5521	maltodextrose utilization protein MalA
JAV55_RS13150	COG1388	LysM domain
JAV55_RS13155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JAV55_RS13160	COG4709	membrane
JAV55_RS13165	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JAV55_RS13170	COG0735	belongs to the Fur family
JAV55_RS13175	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JAV55_RS13180	COG1121	(ABC) transporter
JAV55_RS13185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS13195	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JAV55_RS13200	COG0513	Belongs to the DEAD box helicase family
JAV55_RS13210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JAV55_RS13215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JAV55_RS13220	COG2384	SAM-dependent methyltransferase
JAV55_RS13265	COG5444	nuclease activity
JAV55_RS13280	COG2010	Cytochrome c
JAV55_RS13285	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JAV55_RS13290	COG0358	DNA primase activity
JAV55_RS13295	COG1671	Belongs to the UPF0178 family
JAV55_RS13300	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JAV55_RS13305	COG0517	IMP dehydrogenase activity
JAV55_RS13310	COG0751	glycine-tRNA ligase activity
JAV55_RS13315	COG0752	glycyl-tRNA synthetase alpha subunit
JAV55_RS13320	COG1381	Involved in DNA repair and RecF pathway recombination
JAV55_RS13330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JAV55_RS13335	COG0295	cytidine deaminase activity
JAV55_RS13340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JAV55_RS13345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JAV55_RS13350	COG1480	7TM receptor with intracellular HD hydrolase
JAV55_RS13355	COG1702	phosphate starvation-inducible protein PhoH
JAV55_RS13360	COG0561	phosphatase activity
JAV55_RS13375	COG4864	UPF0365 protein
JAV55_RS13380	COG1030	water channel activity
JAV55_RS13385	COG1610	YqeY-like protein
JAV55_RS13390	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JAV55_RS13395	COG1283	sodium-dependent phosphate transmembrane transporter activity
JAV55_RS13400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JAV55_RS13405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JAV55_RS13410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JAV55_RS13415	COG2264	protein methyltransferase activity
JAV55_RS13420	COG0484	heat shock protein binding
JAV55_RS13425	COG0443	Heat shock 70 kDa protein
JAV55_RS13430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JAV55_RS13435	COG1420	regulation of RNA biosynthetic process
JAV55_RS13440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JAV55_RS13445	COG0481	GTPase activity
JAV55_RS13455	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS13460	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JAV55_RS13465	COG0268	Binds directly to 16S ribosomal RNA
JAV55_RS13470	COG1466	dna polymerase III delta subunit
JAV55_RS13480	COG2333	competence protein COMEC
JAV55_RS13480	COG0658	competence protein
JAV55_RS13485	COG2131	deaminase
JAV55_RS13490	COG1596	polysaccharide export
JAV55_RS13490	COG1555	photosystem II stabilization
JAV55_RS13495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JAV55_RS13500	COG2226	methyltransferase
JAV55_RS13505	COG0799	negative regulation of ribosome biogenesis
JAV55_RS13510	COG1713	HD superfamily hydrolase involved in NAD metabolism
JAV55_RS13515	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JAV55_RS13520	COG1534	Rna-binding protein
JAV55_RS13525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JAV55_RS13530	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JAV55_RS13535	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JAV55_RS13550	COG2755	lipolytic protein G-D-S-L family
JAV55_RS13555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS13560	COG5609	conserved protein (DUF2294)
JAV55_RS13565	COG3383	formate dehydrogenase (NAD+) activity
JAV55_RS13570	COG2427	Protein of unknown function (DUF1641)
JAV55_RS13600	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS13665	COG2197	response regulator
JAV55_RS13670	COG4585	Histidine kinase
JAV55_RS13675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS13680	COG0730	response to heat
JAV55_RS13685	COG0425	Belongs to the sulfur carrier protein TusA family
JAV55_RS13690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS13690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_RS13695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_RS13695	COG0425	Belongs to the sulfur carrier protein TusA family
JAV55_RS13700	COG2210	Belongs to the sulfur carrier protein TusA family
JAV55_RS13705	COG1937	Protein conserved in bacteria
JAV55_RS13750	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JAV55_RS13755	COG0113	porphobilinogen synthase activity
JAV55_RS13760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JAV55_RS13765	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JAV55_RS13770	COG1733	regulation of RNA biosynthetic process
JAV55_RS13775	COG3239	Fatty acid desaturase
JAV55_RS13780	COG4585	Histidine kinase
JAV55_RS13785	COG2197	response regulator
JAV55_RS13790	COG0492	ferredoxin-NADP+ reductase activity
JAV55_RS13795	COG0747	negative chemotaxis
JAV55_RS13800	COG0601	transmembrane transport
JAV55_RS13805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JAV55_RS13810	COG0444	Belongs to the ABC transporter superfamily
JAV55_RS13815	COG4608	Belongs to the ABC transporter superfamily
JAV55_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS13850	COG2124	cytochrome p450
JAV55_RS13855	COG0730	response to heat
JAV55_RS13865	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS13870	COG1621	beta-fructofuranosidase activity
JAV55_RS13875	COG3716	PTS system mannose fructose sorbose family IID component
JAV55_RS13880	COG3715	PTS system
JAV55_RS13885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS13890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS13895	COG3933	PFAM sigma-54 factor interaction domain-containing protein
JAV55_RS13895	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JAV55_RS13920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JAV55_RS13925	COG0656	L-ascorbic acid biosynthetic process
JAV55_RS13930	COG2814	Major facilitator Superfamily
JAV55_RS13935	COG1733	regulation of RNA biosynthetic process
JAV55_RS13940	COG3340	Belongs to the peptidase S51 family
JAV55_RS13945	COG1587	Uroporphyrinogen-III synthase
JAV55_RS13955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS13960	COG0583	DNA-binding transcription factor activity
JAV55_RS13965	COG2814	Major facilitator Superfamily
JAV55_RS13975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JAV55_RS13975	COG2124	cytochrome p450
JAV55_RS13980	COG1309	transcriptional regulator
JAV55_RS13985	COG1404	Belongs to the peptidase S8 family
JAV55_RS13990	COG2226	methyltransferase
JAV55_RS14015	COG0626	cystathionine gamma-synthase activity
JAV55_RS14020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_RS14025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JAV55_RS14030	COG2226	methyltransferase
JAV55_RS14045	COG0768	penicillin binding
JAV55_RS14050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JAV55_RS14055	COG0572	uridine kinase
JAV55_RS14060	COG0826	peptidase U32
JAV55_RS14065	COG0826	peptidase U32
JAV55_RS14070	COG4122	O-methyltransferase activity
JAV55_RS14075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JAV55_RS14080	COG3906	Belongs to the UPF0473 family
JAV55_RS14085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JAV55_RS14090	COG4472	Bacterial protein of unknown function (DUF965)
JAV55_RS14095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JAV55_RS14100	COG0628	permease
JAV55_RS14115	COG3881	PFAM PRC-barrel domain
JAV55_RS14120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JAV55_RS14125	COG0457	Tetratricopeptide repeat
JAV55_RS14130	COG0482	sulfurtransferase activity
JAV55_RS14135	COG1104	cysteine desulfurase activity
JAV55_RS14140	COG1959	2 iron, 2 sulfur cluster binding
JAV55_RS14145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JAV55_RS14150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JAV55_RS14160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JAV55_RS14165	COG0124	histidyl-tRNA synthetase
JAV55_RS14175	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS14175	COG3103	Sh3 type 3 domain protein
JAV55_RS14175	COG4991	sh3 domain protein
JAV55_RS14180	COG1490	D-aminoacyl-tRNA deacylase activity
JAV55_RS14185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JAV55_RS14190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JAV55_RS14195	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JAV55_RS14195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JAV55_RS14200	COG5416	Lipopolysaccharide assembly protein A domain
JAV55_RS14205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JAV55_RS14205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JAV55_RS14215	COG2244	polysaccharide biosynthetic process
JAV55_RS14220	COG2323	membrane
JAV55_RS14230	COG1862	Preprotein translocase
JAV55_RS14235	COG0343	queuine tRNA-ribosyltransferase activity
JAV55_RS14240	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JAV55_RS14250	COG2255	four-way junction helicase activity
JAV55_RS14255	COG0632	four-way junction helicase activity
JAV55_RS14265	COG2112	serine threonine protein kinase
JAV55_RS14275	COG2318	DinB family
JAV55_RS14280	COG4195	phage-related replication protein
JAV55_RS14295	COG0217	transcriptional regulatory protein
JAV55_RS14305	COG1388	LysM domain
JAV55_RS14310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JAV55_RS14315	COG0157	Belongs to the NadC ModD family
JAV55_RS14320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JAV55_RS14325	COG1104	cysteine desulfurase activity
JAV55_RS14330	COG1827	regulation of RNA biosynthetic process
JAV55_RS14335	COG0077	Prephenate dehydratase
JAV55_RS14340	COG4492	Belongs to the UPF0735 family
JAV55_RS14345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JAV55_RS14350	COG3290	protein histidine kinase activity
JAV55_RS14355	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JAV55_RS14360	COG2868	ribosomal protein
JAV55_RS14365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JAV55_RS14370	COG1994	Peptidase M50
JAV55_RS14375	COG0739	heme binding
JAV55_RS14380	COG3832	glyoxalase III activity
JAV55_RS14385	COG0640	Transcriptional regulator
JAV55_RS14390	COG2894	cell division
JAV55_RS14395	COG0850	regulation of cytokinetic process
JAV55_RS14400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JAV55_RS14410	COG1077	Cell shape determining protein MreB Mrl
JAV55_RS14415	COG2003	Belongs to the UPF0758 family
JAV55_RS14420	COG0424	maF-like protein
JAV55_RS14430	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JAV55_RS14435	COG0285	dihydrofolate synthase activity
JAV55_RS14440	COG0525	valine-tRNA ligase activity
JAV55_RS14450	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JAV55_RS14455	COG1388	LysM domain
JAV55_RS14460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JAV55_RS14465	COG0113	porphobilinogen synthase activity
JAV55_RS14470	COG1587	Uroporphyrinogen-III synthase
JAV55_RS14475	COG0181	hydroxymethylbilane synthase activity
JAV55_RS14480	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JAV55_RS14485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JAV55_RS14495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JAV55_RS14500	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JAV55_RS14505	COG1067	ATP-dependent peptidase activity
JAV55_RS14505	COG0470	DNA polymerase III
JAV55_RS14510	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JAV55_RS14515	COG0544	peptidyl-prolyl cis-trans isomerase activity
JAV55_RS14520	COG0457	Tetratricopeptide repeat
JAV55_RS14520	COG1477	protein flavinylation
JAV55_RS14525	COG0066	3-isopropylmalate dehydratase activity
JAV55_RS14530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JAV55_RS14535	COG0473	3-isopropylmalate dehydrogenase activity
JAV55_RS14540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JAV55_RS14545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JAV55_RS14550	COG0440	acetolactate synthase activity
JAV55_RS14555	COG0028	Belongs to the TPP enzyme family
JAV55_RS14560	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_RS14570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JAV55_RS14625	COG5444	nuclease activity
JAV55_RS14630	COG0457	Tetratricopeptide repeat
JAV55_RS14655	COG0622	Phosphoesterase
JAV55_RS14660	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JAV55_RS14665	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JAV55_RS14670	COG5401	PFAM Sporulation and spore germination
JAV55_RS14675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JAV55_RS14680	COG1846	Transcriptional regulator
JAV55_RS14685	COG2197	response regulator
JAV55_RS14690	COG4221	oxidoreductase activity
JAV55_RS14695	COG0824	Thioesterase
JAV55_RS14700	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JAV55_RS14705	COG1053	succinate dehydrogenase
JAV55_RS14710	COG2009	succinate dehydrogenase
JAV55_RS14715	COG1719	4-vinyl reductase, 4VR
JAV55_RS14720	COG0527	aspartate kinase activity
JAV55_RS14725	COG0322	excinuclease ABC activity
JAV55_RS14730	COG3118	belongs to the thioredoxin family
JAV55_RS14735	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JAV55_RS14740	COG2086	electron transfer activity
JAV55_RS14745	COG1024	Enoyl-CoA hydratase
JAV55_RS14750	COG1309	transcriptional regulator
JAV55_RS14755	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS14760	COG3766	membrane
JAV55_RS14765	COG1193	negative regulation of DNA recombination
JAV55_RS14770	COG1796	DNA polymerase
JAV55_RS14770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JAV55_RS14775	COG1286	toxin biosynthetic process
JAV55_RS14780	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JAV55_RS14785	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JAV55_RS14805	COG1137	ATPase activity
JAV55_RS14820	COG0072	phenylalanine-tRNA ligase activity
JAV55_RS14820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_RS14825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JAV55_RS14830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JAV55_RS14840	COG1966	Carbon starvation protein
JAV55_RS14850	COG0395	ABC-type sugar transport system, permease component
JAV55_RS14855	COG1175	transmembrane transport
JAV55_RS14860	COG1653	transport
JAV55_RS14865	COG0371	Dehydrogenase
JAV55_RS14870	COG0235	Class ii aldolase
JAV55_RS14875	COG1069	ribulokinase activity
JAV55_RS14880	COG2160	L-arabinose isomerase activity
JAV55_RS14885	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_RS14890	COG1363	Peptidase, m42
JAV55_RS14900	COG3326	Membrane
JAV55_RS14905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JAV55_RS14910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JAV55_RS14915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JAV55_RS14920	COG1346	cytolysis
JAV55_RS14930	COG3540	Alkaline phosphatase
JAV55_RS14935	COG3279	Response regulator of the LytR AlgR family
JAV55_RS14940	COG3275	phosphorelay sensor kinase activity
JAV55_RS14950	COG1011	Hydrolase
JAV55_RS14955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JAV55_RS14965	COG0398	Pfam SNARE associated Golgi protein
JAV55_RS14970	COG1484	DNA-dependent DNA replication
JAV55_RS14975	COG3611	Membrane attachment protein
JAV55_RS14980	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JAV55_RS14990	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JAV55_RS14995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JAV55_RS15000	COG3866	Pectate lyase
JAV55_RS15005	COG0237	dephospho-CoA kinase activity
JAV55_RS15010	COG1971	Probably functions as a manganese efflux pump
JAV55_RS15015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JAV55_RS15020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_RS15020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JAV55_RS15025	COG5002	protein histidine kinase activity
JAV55_RS15030	COG0745	RESPONSE REGULATOR receiver
JAV55_RS15035	COG0039	L-malate dehydrogenase activity
JAV55_RS15040	COG0538	isocitrate dehydrogenase activity
JAV55_RS15045	COG0372	Belongs to the citrate synthase family
JAV55_RS15050	COG2707	UPF0756 membrane protein
JAV55_RS15055	COG0628	permease
JAV55_RS15060	COG3030	protein affecting phage T7 exclusion by the F plasmid
JAV55_RS15070	COG0205	6-phosphofructokinase activity
JAV55_RS15075	COG0825	malonyl-CoA metabolic process
JAV55_RS15080	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JAV55_RS15085	COG0281	malic enzyme
JAV55_RS15090	COG0587	DNA-directed DNA polymerase activity
JAV55_RS15110	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JAV55_RS15120	COG4109	DRTGG domain
JAV55_RS15125	COG1695	Transcriptional regulator
JAV55_RS15130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JAV55_RS15135	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS15145	COG0165	Argininosuccinate lyase
JAV55_RS15150	COG0137	argininosuccinate synthase activity
JAV55_RS15155	COG0521	Mo-molybdopterin cofactor biosynthetic process
JAV55_RS15160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JAV55_RS15165	COG0827	DNA restriction-modification system
JAV55_RS15170	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JAV55_RS15175	COG3874	Sporulation protein YtfJ
JAV55_RS15185	COG1714	RDD family
JAV55_RS15190	COG0616	signal peptide processing
JAV55_RS15195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JAV55_RS15200	COG1566	PFAM secretion protein HlyD family protein
JAV55_RS15205	COG0477	Major facilitator Superfamily
JAV55_RS15215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_RS15225	COG0301	tRNA thio-modification
JAV55_RS15230	COG1104	cysteine desulfurase activity
JAV55_RS15235	COG1114	Component of the transport system for branched-chain amino acids
JAV55_RS15240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JAV55_RS15245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JAV55_RS15250	COG1309	transcriptional regulator
JAV55_RS15255	COG1956	GAF domain-containing protein
JAV55_RS15260	COG2203	Gaf domain
JAV55_RS15260	COG2199	diguanylate cyclase activity
JAV55_RS15265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JAV55_RS15275	COG3152	Membrane
JAV55_RS15280	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JAV55_RS15285	COG1522	sequence-specific DNA binding
JAV55_RS15295	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JAV55_RS15300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JAV55_RS15305	COG0454	-acetyltransferase
JAV55_RS15310	COG0517	IMP dehydrogenase activity
JAV55_RS15315	COG0123	including yeast histone deacetylase and acetoin utilization protein
JAV55_RS15320	COG1360	Flagellar Motor Protein
JAV55_RS15325	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JAV55_RS15330	COG1609	Transcriptional regulator
JAV55_RS15335	COG1605	Chorismate mutase
JAV55_RS15335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JAV55_RS15345	COG3118	belongs to the thioredoxin family
JAV55_RS15350	COG4980	gas vesicle protein
JAV55_RS15355	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JAV55_RS15360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JAV55_RS15365	COG1674	ftsk spoiiie
JAV55_RS15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JAV55_RS15375	COG4848	Belongs to the UPF0354 family
JAV55_RS15380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS15390	COG1363	Peptidase, m42
JAV55_RS15395	COG5584	Small secreted protein
JAV55_RS15400	COG0281	malic enzyme
JAV55_RS15405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JAV55_RS15410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JAV55_RS15420	COG0510	thiamine kinase activity
JAV55_RS15425	COG1523	belongs to the glycosyl hydrolase 13 family
JAV55_RS15430	COG1597	lipid kinase activity
JAV55_RS15440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JAV55_RS15445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JAV55_RS15460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_RS15465	COG2252	PERMEase
JAV55_RS15470	COG1349	DNA-binding transcription factor activity
JAV55_RS15475	COG1187	pseudouridine synthase activity
JAV55_RS15480	COG2244	polysaccharide biosynthetic process
JAV55_RS15485	COG2081	HI0933 family
JAV55_RS15490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JAV55_RS15500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JAV55_RS15515	COG5578	integral membrane protein
JAV55_RS15520	COG0673	inositol 2-dehydrogenase activity
JAV55_RS15525	COG1653	transport
JAV55_RS15530	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JAV55_RS15535	COG4209	transmembrane transport
JAV55_RS15540	COG2207	Transcriptional regulator
JAV55_RS15545	COG1653	transport
JAV55_RS15550	COG0395	ABC-type sugar transport system, permease component
JAV55_RS15555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_RS15560	COG1073	alpha beta
JAV55_RS15570	COG0583	DNA-binding transcription factor activity
JAV55_RS15575	COG0346	lactoylglutathione lyase activity
JAV55_RS15580	COG0495	leucyl-tRNA aminoacylation
JAV55_RS15590	COG2814	Major facilitator Superfamily
JAV55_RS15600	COG2433	Pfam Transposase IS66
JAV55_RS15605	COG0577	efflux transmembrane transporter activity
JAV55_RS15610	COG1136	(ABC) transporter
JAV55_RS15620	COG1131	(ABC) transporter
JAV55_RS15625	COG1725	Transcriptional regulator
JAV55_RS15635	COG1242	4 iron, 4 sulfur cluster binding
JAV55_RS15640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JAV55_RS15645	COG1301	dicarboxylic acid transport
JAV55_RS15655	COG2267	carboxylic ester hydrolase activity
JAV55_RS15660	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JAV55_RS15665	COG0671	phosphoesterase, PA-phosphatase related
JAV55_RS15670	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_RS15670	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS15675	COG0367	asparagine synthase
JAV55_RS15680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JAV55_RS15685	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JAV55_RS15700	COG1506	peptidase
JAV55_RS15705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JAV55_RS15710	COG1116	anion transmembrane transporter activity
JAV55_RS15715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JAV55_RS15720	COG0494	nUDIX hydrolase
JAV55_RS15730	COG4824	toxin secretion phage lysis holin
JAV55_RS15735	COG0783	Belongs to the Dps family
JAV55_RS15750	COG1854	S-ribosylhomocysteine lyase activity
JAV55_RS15755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JAV55_RS15760	COG0288	reversible hydration of carbon dioxide
JAV55_RS15765	COG0523	cobalamin synthesis protein
JAV55_RS15770	COG0803	Belongs to the bacterial solute-binding protein 9 family
JAV55_RS15775	COG0254	rRNA binding
JAV55_RS15780	COG1271	oxidase subunit
JAV55_RS15785	COG1294	oxidase, subunit
JAV55_RS15800	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_RS15805	COG0318	PFAM AMP-dependent synthetase and ligase
JAV55_RS15810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JAV55_RS15815	COG0596	Alpha beta hydrolase
JAV55_RS15820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JAV55_RS15825	COG1169	isochorismate synthase
JAV55_RS15830	COG1575	Belongs to the MenA family. Type 1 subfamily
JAV55_RS15835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JAV55_RS15840	COG0058	SHG alpha-glucan phosphorylase activity
JAV55_RS15845	COG0297	glycogen (starch) synthase activity
JAV55_RS15850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JAV55_RS15855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JAV55_RS15985	COG1609	Transcriptional regulator
JAV55_RS15990	COG3859	Proton-coupled thiamine transporter YuaJ
JAV55_RS15995	COG3764	Sortase (surface protein transpeptidase)
JAV55_RS16010	COG0457	Tetratricopeptide repeat
JAV55_RS16015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JAV55_RS16020	COG0569	domain protein
JAV55_RS16025	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_RS16035	COG2318	DinB family
JAV55_RS16045	COG1454	alcohol dehydrogenase
JAV55_RS16050	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS16055	COG1510	regulation of RNA biosynthetic process
JAV55_RS16065	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JAV55_RS16070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JAV55_RS16075	COG2140	Oxalate decarboxylase
JAV55_RS16110	COG1397	ADP-ribosylglycohydrolase
JAV55_RS16145	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
JAV55_RS16160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JAV55_RS16165	COG0726	polysaccharide deacetylase
JAV55_RS16170	COG1408	metallophosphoesterase
JAV55_RS16175	COG1968	undecaprenyl-diphosphatase activity
JAV55_RS16180	COG0628	permease
JAV55_RS16185	COG0673	inositol 2-dehydrogenase activity
JAV55_RS16190	COG0693	protein deglycase activity
JAV55_RS16195	COG0840	transmembrane signaling receptor activity
JAV55_RS16200	COG0840	transmembrane signaling receptor activity
JAV55_RS16205	COG0840	transmembrane signaling receptor activity
JAV55_RS16215	COG2070	2-Nitropropane dioxygenase
JAV55_RS16220	COG0432	Pfam Uncharacterised protein family UPF0047
JAV55_RS16225	COG0366	Alpha amylase catalytic
JAV55_RS16240	COG5297	Belongs to the glycosyl hydrolase family 6
JAV55_RS16245	COG1253	flavin adenine dinucleotide binding
JAV55_RS16250	COG2738	Putative neutral zinc metallopeptidase
JAV55_RS16265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JAV55_RS16280	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JAV55_RS16290	COG0166	Belongs to the GPI family
JAV55_RS16295	COG1979	alcohol dehydrogenase
JAV55_RS16300	COG2155	Conserved Protein
JAV55_RS16305	COG1098	S1 RNA binding domain
JAV55_RS16310	COG0436	Aminotransferase
JAV55_RS16315	COG1522	sequence-specific DNA binding
JAV55_RS16320	COG2267	carboxylic ester hydrolase activity
JAV55_RS16335	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JAV55_RS16350	COG5018	Exonuclease
JAV55_RS16355	COG2814	Major facilitator Superfamily
JAV55_RS16360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_RS16365	COG3011	Protein conserved in bacteria
JAV55_RS16375	COG3290	protein histidine kinase activity
JAV55_RS16380	COG4565	transcriptional regulatory protein
JAV55_RS16390	COG1183	phosphatidylcholine synthase activity
JAV55_RS16395	COG0586	Pfam SNARE associated Golgi protein
JAV55_RS16400	COG0688	phosphatidylethanolamine metabolic process
JAV55_RS16405	COG3493	citrate carrier protein
JAV55_RS16415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JAV55_RS16415	COG2111	Na H antiporter
JAV55_RS16420	COG2111	Na H antiporter
JAV55_RS16425	COG1006	Multisubunit Na H antiporter MnhC subunit
JAV55_RS16430	COG0651	ATP synthesis coupled electron transport
JAV55_RS16435	COG1863	multisubunit Na H antiporter MnhE subunit
JAV55_RS16440	COG2212	antiporter activity
JAV55_RS16445	COG1320	monovalent cation:proton antiporter activity
JAV55_RS16450	COG2050	protein possibly involved in aromatic compounds catabolism
JAV55_RS16455	COG2197	response regulator
JAV55_RS16460	COG4585	Histidine kinase
JAV55_RS16470	COG0142	geranyltranstransferase activity
JAV55_RS16485	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JAV55_RS16490	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JAV55_RS16495	COG1335	isochorismatase
JAV55_RS16500	COG5506	Protein of unknown function (DUF1694)
JAV55_RS16515	COG0628	permease
JAV55_RS16520	COG1959	2 iron, 2 sulfur cluster binding
JAV55_RS16525	COG0657	acetylesterase activity
JAV55_RS16535	COG1418	mRNA catabolic process
JAV55_RS16540	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS16550	COG1511	domain protein
JAV55_RS16555	COG0433	COG0433 Predicted ATPase
JAV55_RS16555	COG1674	ftsk spoiiie
JAV55_RS16560	COG4499	WXG100 protein secretion system (Wss), protein YukC
JAV55_RS16565	COG5417	Belongs to the EsaB family
JAV55_RS16570	COG4842	Belongs to the WXG100 family
JAV55_RS16575	COG1115	amino acid carrier protein
JAV55_RS16580	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JAV55_RS16580	COG2508	Transcriptional regulator
JAV55_RS16585	COG0686	Belongs to the AlaDH PNT family
JAV55_RS16595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JAV55_RS16600	COG1268	BioY protein
JAV55_RS16605	COG2056	Na+-H+ antiporter family
JAV55_RS16610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JAV55_RS16615	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JAV55_RS16620	COG3584	3D domain protein
JAV55_RS16635	COG1252	NADH dehydrogenase
JAV55_RS16640	COG0492	ferredoxin-NADP+ reductase activity
JAV55_RS16655	COG0456	acetyltransferase
JAV55_RS16660	COG0316	Belongs to the HesB IscA family
JAV55_RS16665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JAV55_RS16670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_RS16675	COG4844	belongs to the
JAV55_RS16680	COG1252	NADH dehydrogenase
JAV55_RS16685	COG5646	InterPro IPR014922
JAV55_RS16695	COG0457	Tetratricopeptide repeat
JAV55_RS16700	COG3479	Phenolic acid decarboxylase
JAV55_RS16710	COG4837	Protein of unknown function (DUF1462)
JAV55_RS16715	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JAV55_RS16720	COG1506	peptidase
JAV55_RS16720	COG0823	Involved in the tonB-independent uptake of proteins
JAV55_RS16720	COG4946	Tricorn protease homolog
JAV55_RS16725	COG0083	homoserine kinase activity
JAV55_RS16730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JAV55_RS16735	COG0460	homoserine dehydrogenase
JAV55_RS16745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JAV55_RS16750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JAV55_RS16755	COG0647	UMP catabolic process
JAV55_RS16760	COG2445	Protein of unknown function DUF86
JAV55_RS16765	COG4470	Protein conserved in bacteria
JAV55_RS16780	COG0739	heme binding
JAV55_RS16790	COG0733	neurotransmitter:sodium symporter activity
JAV55_RS16800	COG3377	Domain of unknown function (DUF1805)
JAV55_RS16805	COG0737	Belongs to the 5'-nucleotidase family
JAV55_RS16810	COG0730	response to heat
JAV55_RS16815	COG1801	Protein of unknown function DUF72
JAV55_RS16825	COG3226	Transcriptional regulator
JAV55_RS16835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JAV55_RS16840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JAV55_RS16845	COG2508	Transcriptional regulator
JAV55_RS16850	COG2814	Major facilitator Superfamily
JAV55_RS16855	COG1288	antiporter activity
JAV55_RS16860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_RS16865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JAV55_RS16870	COG2356	endonuclease I
JAV55_RS16880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JAV55_RS16895	COG0457	Tetratricopeptide repeat
JAV55_RS16900	COG0719	Fe-S assembly protein
JAV55_RS16905	COG0822	iron-sulfur transferase activity
JAV55_RS16910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JAV55_RS16915	COG0719	Fe-S assembly protein
JAV55_RS16920	COG0396	ATPase activity
JAV55_RS16930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JAV55_RS16935	COG1464	Belongs to the NlpA lipoprotein family
JAV55_RS16940	COG2011	ABC-type metal ion transport system permease component
JAV55_RS16945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JAV55_RS16955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JAV55_RS16960	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JAV55_RS16970	COG0509	glycine decarboxylation via glycine cleavage system
JAV55_RS16975	COG1393	Belongs to the ArsC family
JAV55_RS16980	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS16985	COG0183	Belongs to the thiolase family
JAV55_RS16990	COG1250	3-hydroxyacyl-CoA dehydrogenase
JAV55_RS16990	COG1024	Enoyl-CoA hydratase
JAV55_RS17005	COG5577	PFAM Coat F domain
JAV55_RS17020	COG1120	ATPase activity
JAV55_RS17025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS17035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS17050	COG1686	Belongs to the peptidase S11 family
JAV55_RS17055	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS17060	COG0783	Belongs to the Dps family
JAV55_RS17065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_RS17070	COG0745	RESPONSE REGULATOR receiver
JAV55_RS17075	COG2770	Histidine kinase
JAV55_RS17075	COG2205	protein histidine kinase activity
JAV55_RS17085	COG1309	transcriptional regulator
JAV55_RS17090	COG0114	fumarate hydratase activity
JAV55_RS17100	COG0697	spore germination
JAV55_RS17105	COG0814	amino acid
JAV55_RS17120	COG2197	response regulator
JAV55_RS17125	COG4585	Histidine kinase
JAV55_RS17130	COG4758	membrane
JAV55_RS17140	COG1842	Phage shock protein A
JAV55_RS17145	COG4758	membrane
JAV55_RS17150	COG4677	pectinesterase activity
JAV55_RS17155	COG2096	Adenosyltransferase
JAV55_RS17160	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS17175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_RS17180	COG1120	ATPase activity
JAV55_RS17185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS17190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS17195	COG1802	Transcriptional regulator
JAV55_RS17200	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS17205	COG2258	MOSC domain
JAV55_RS17210	COG0583	DNA-binding transcription factor activity
JAV55_RS17220	COG2721	sulfolactate sulfo-lyase activity
JAV55_RS17225	COG0246	Mannitol dehydrogenase
JAV55_RS17230	COG1609	Transcriptional regulator
JAV55_RS17235	COG2211	Major facilitator Superfamily
JAV55_RS17240	COG1904	glucuronate isomerase
JAV55_RS17245	COG2205	protein histidine kinase activity
JAV55_RS17250	COG0745	RESPONSE REGULATOR receiver
JAV55_RS17255	COG1120	ATPase activity
JAV55_RS17260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS17265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS17270	COG0531	amino acid
JAV55_RS17280	COG1988	membrane-bound metal-dependent
JAV55_RS17285	COG1368	sulfuric ester hydrolase activity
JAV55_RS17290	COG2814	Major facilitator Superfamily
JAV55_RS17295	COG0656	L-ascorbic acid biosynthetic process
JAV55_RS17300	COG1940	carbohydrate kinase activity
JAV55_RS17305	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JAV55_RS17315	COG3973	AAA domain
JAV55_RS17320	COG2860	membrane
JAV55_RS17325	COG0456	acetyltransferase
JAV55_RS17325	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JAV55_RS17330	COG0456	acetyltransferase
JAV55_RS17335	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JAV55_RS17340	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JAV55_RS17345	COG2217	Heavy metal translocating P-type atpase
JAV55_RS17355	COG1175	transmembrane transport
JAV55_RS17360	COG0395	ABC-type sugar transport system, permease component
JAV55_RS17365	COG1501	Belongs to the glycosyl hydrolase 31 family
JAV55_RS17370	COG1472	Belongs to the glycosyl hydrolase 3 family
JAV55_RS17375	COG1121	(ABC) transporter
JAV55_RS17380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JAV55_RS17385	COG0803	Belongs to the bacterial solute-binding protein 9 family
JAV55_RS17400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JAV55_RS17400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JAV55_RS17405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS17405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JAV55_RS17405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS17425	COG2217	Heavy metal translocating P-type atpase
JAV55_RS17430	COG2608	mercury ion transmembrane transporter activity
JAV55_RS17435	COG1937	Protein conserved in bacteria
JAV55_RS17440	COG0693	protein deglycase activity
JAV55_RS17445	COG1349	DNA-binding transcription factor activity
JAV55_RS17450	COG1070	Carbohydrate kinase
JAV55_RS17455	COG4952	isomerase
JAV55_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS17465	COG3347	Dehydrogenase
JAV55_RS17470	COG2814	Major facilitator Superfamily
JAV55_RS17475	COG2814	Major facilitator Superfamily
JAV55_RS17485	COG2124	cytochrome p450
JAV55_RS17495	COG1846	Transcriptional regulator
JAV55_RS17505	COG0673	inositol 2-dehydrogenase activity
JAV55_RS17510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JAV55_RS17515	COG1054	Belongs to the UPF0176 family
JAV55_RS17525	COG1191	sigma factor activity
JAV55_RS17535	COG2140	Oxalate decarboxylase
JAV55_RS17565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JAV55_RS17655	COG1705	Flagellar rod assembly protein muramidase FlgJ
JAV55_RS17665	COG3953	SLT domain
JAV55_RS17665	COG5280	Phage tail tape measure protein TP901
JAV55_RS17725	COG1802	Transcriptional regulator
JAV55_RS17725	COG4626	Terminase
JAV55_RS17870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JAV55_RS17875	COG0557	exoribonuclease II activity
JAV55_RS17880	COG1647	Serine aminopeptidase, S33
JAV55_RS17885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JAV55_RS17890	COG2002	toxin-antitoxin pair type II binding
JAV55_RS17895	COG1476	TRANSCRIPTIONal
JAV55_RS17900	COG1396	sequence-specific DNA binding
JAV55_RS17905	COG1396	sequence-specific DNA binding
JAV55_RS17910	COG1174	glycine betaine transport
JAV55_RS17915	COG1732	Glycine betaine
JAV55_RS17920	COG1174	glycine betaine transport
JAV55_RS17925	COG0517	IMP dehydrogenase activity
JAV55_RS17925	COG1125	glycine betaine transport
JAV55_RS17930	COG1510	regulation of RNA biosynthetic process
JAV55_RS17935	COG2095	MarC family integral membrane protein
JAV55_RS17950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS17960	COG0693	protein deglycase activity
JAV55_RS17965	COG0148	phosphopyruvate hydratase activity
JAV55_RS17970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JAV55_RS17975	COG0149	triose-phosphate isomerase activity
JAV55_RS17980	COG0126	phosphoglycerate kinase activity
JAV55_RS17985	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JAV55_RS17990	COG2390	Transcriptional regulator
JAV55_RS17995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_RS18000	COG1113	amino acid transport
JAV55_RS18020	COG1556	Lactate utilization protein
JAV55_RS18025	COG1139	Iron-sulfur cluster binding protein
JAV55_RS18030	COG0247	lactate metabolic process
JAV55_RS18035	COG2186	Transcriptional regulator
JAV55_RS18040	COG1620	l-lactate permease
JAV55_RS18045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JAV55_RS18055	COG5039	Polysaccharide pyruvyl transferase
JAV55_RS18060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_RS18065	COG0110	maltose O-acetyltransferase activity
JAV55_RS18070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JAV55_RS18075	COG2244	polysaccharide biosynthetic process
JAV55_RS18080	COG1216	Glycosyl transferase, family 2
JAV55_RS18085	COG5039	Polysaccharide pyruvyl transferase
JAV55_RS18090	COG1216	Glycosyl transferase, family 2
JAV55_RS18100	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS18105	COG1215	transferase activity, transferring glycosyl groups
JAV55_RS18110	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS18115	COG1086	Polysaccharide biosynthesis protein
JAV55_RS18120	COG0489	protein tyrosine kinase activity
JAV55_RS18125	COG3944	biosynthesis protein
JAV55_RS18130	COG1396	sequence-specific DNA binding
JAV55_RS18140	COG2249	NAD(P)H dehydrogenase (quinone) activity
JAV55_RS18145	COG2271	Major facilitator Superfamily
JAV55_RS18155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JAV55_RS18170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JAV55_RS18180	COG1733	regulation of RNA biosynthetic process
JAV55_RS18185	COG1902	pentaerythritol trinitrate reductase activity
JAV55_RS18190	COG1621	beta-fructofuranosidase activity
JAV55_RS18195	COG1621	beta-fructofuranosidase activity
JAV55_RS18210	COG0740	serine-type endopeptidase activity
JAV55_RS18215	COG1611	Belongs to the LOG family
JAV55_RS18220	COG1694	Mazg nucleotide pyrophosphohydrolase
JAV55_RS18225	COG1078	dGTPase activity
JAV55_RS18230	COG0659	secondary active sulfate transmembrane transporter activity
JAV55_RS18235	COG0288	reversible hydration of carbon dioxide
JAV55_RS18240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_RS18245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JAV55_RS18250	COG0640	Transcriptional regulator
JAV55_RS18260	COG2732	(Barnase) inhibitor
JAV55_RS18265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JAV55_RS18270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS18275	COG1481	regulation of sporulation
JAV55_RS18280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JAV55_RS18285	COG1660	Displays ATPase and GTPase activities
JAV55_RS18290	COG1051	belongs to the nudix hydrolase family
JAV55_RS18295	COG0492	ferredoxin-NADP+ reductase activity
JAV55_RS18300	COG0457	Tetratricopeptide repeat
JAV55_RS18305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JAV55_RS18310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JAV55_RS18310	COG0140	phosphoribosyl-ATP diphosphatase activity
JAV55_RS18315	COG0107	imidazoleglycerol-phosphate synthase activity
JAV55_RS18320	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JAV55_RS18325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JAV55_RS18330	COG0131	Imidazoleglycerol-phosphate dehydratase
JAV55_RS18335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JAV55_RS18340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JAV55_RS18345	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JAV55_RS18350	COG4990	cell redox homeostasis
JAV55_RS18355	COG5297	Belongs to the glycosyl hydrolase family 6
JAV55_RS18360	COG0110	maltose O-acetyltransferase activity
JAV55_RS18365	COG0546	phosphoglycolate phosphatase activity
JAV55_RS18370	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JAV55_RS18375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JAV55_RS18380	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JAV55_RS18385	COG1846	Transcriptional regulator
JAV55_RS18390	COG2814	Major facilitator Superfamily
JAV55_RS18395	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JAV55_RS18400	COG1950	PFAM Membrane protein of
JAV55_RS18405	COG1983	PspC domain protein
JAV55_RS18410	COG3595	metallopeptidase activity
JAV55_RS18430	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JAV55_RS18435	COG0556	nucleotide-excision repair
JAV55_RS18440	COG4897	Protein conserved in bacteria
JAV55_RS18450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_RS18460	COG0793	Belongs to the peptidase S41A family
JAV55_RS18460	COG3409	Peptidoglycan-binding domain 1 protein
JAV55_RS18465	COG0473	3-isopropylmalate dehydrogenase activity
JAV55_RS18470	COG3883	PFAM NLP P60 protein
JAV55_RS18470	COG0791	NLP P60 protein
JAV55_RS18475	COG2177	Part of the ABC transporter FtsEX involved in
JAV55_RS18480	COG2884	Cell division ATP-binding protein ftsE
JAV55_RS18485	COG2010	Cytochrome c
JAV55_RS18490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS18500	COG0653	protein targeting
JAV55_RS18505	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JAV55_RS18520	COG1516	flagellar protein fliS
JAV55_RS18525	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JAV55_RS18530	COG1334	flagellar protein FlaG
JAV55_RS18535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JAV55_RS18540	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JAV55_RS18545	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JAV55_RS18555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JAV55_RS18560	COG4786	Flagellar basal body rod
JAV55_RS18560	COG1256	bacterial-type flagellum assembly
JAV55_RS18565	COG3418	PFAM FlgN family protein
JAV55_RS18570	COG2747	anti-sigma28 factor FlgM
JAV55_RS18580	COG1040	competence protein
JAV55_RS18590	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JAV55_RS18595	COG1307	EDD domain protein, DegV family
JAV55_RS18600	COG2197	response regulator
JAV55_RS18605	COG4585	Histidine kinase
JAV55_RS18610	COG1739	Uncharacterized protein family UPF0029
JAV55_RS18615	COG1316	TRANSCRIPTIONal
JAV55_RS18625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JAV55_RS18630	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS18635	COG1215	transferase activity, transferring glycosyl groups
JAV55_RS18640	COG3206	protein involved in exopolysaccharide biosynthesis
JAV55_RS18645	COG3307	-O-antigen
JAV55_RS18650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JAV55_RS18655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JAV55_RS18660	COG0297	glycogen (starch) synthase activity
JAV55_RS18660	COG0438	transferase activity, transferring glycosyl groups
JAV55_RS18665	COG2244	polysaccharide biosynthetic process
JAV55_RS18675	COG0860	N-Acetylmuramoyl-L-alanine amidase
JAV55_RS18675	COG2247	cell wall binding repeat
JAV55_RS18680	COG2385	sporulation resulting in formation of a cellular spore
JAV55_RS18680	COG2247	cell wall binding repeat
JAV55_RS18690	COG1316	TRANSCRIPTIONal
JAV55_RS18695	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JAV55_RS18705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JAV55_RS18710	COG1134	teichoic acid transport
JAV55_RS18715	COG1682	transport, permease protein
JAV55_RS18720	COG0463	Glycosyl transferase, family 2
JAV55_RS18720	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_RS18725	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_RS18730	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JAV55_RS18735	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JAV55_RS18740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JAV55_RS18745	COG4193	domain, Protein
JAV55_RS18750	COG1482	cell wall glycoprotein biosynthetic process
JAV55_RS18770	COG0800	Aldolase
JAV55_RS18775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_RS18780	COG1609	Transcriptional regulator
JAV55_RS18785	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JAV55_RS18790	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS18795	COG1063	alcohol dehydrogenase
JAV55_RS18805	COG2814	Major facilitator Superfamily
JAV55_RS18810	COG1316	TRANSCRIPTIONal
JAV55_RS18815	COG0561	phosphatase activity
JAV55_RS18820	COG0791	NLP P60 protein
JAV55_RS18830	COG2843	Capsule synthesis protein
JAV55_RS18840	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JAV55_RS18845	COG1609	Transcriptional regulator
JAV55_RS18850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_RS18855	COG1869	D-ribose catabolic process
JAV55_RS18860	COG1129	ABC transporter
JAV55_RS18865	COG1172	Belongs to the binding-protein-dependent transport system permease family
JAV55_RS18870	COG1879	ABC-type sugar transport system periplasmic component
JAV55_RS18875	COG3527	Alpha-acetolactate decarboxylase
JAV55_RS18880	COG0028	Belongs to the TPP enzyme family
JAV55_RS18885	COG0583	DNA-binding transcription factor activity
JAV55_RS18890	COG0405	Gamma-glutamyltransferase
JAV55_RS18895	COG1522	sequence-specific DNA binding
JAV55_RS18900	COG2059	Chromate
JAV55_RS18905	COG2059	Chromate
JAV55_RS18910	COG4464	protein tyrosine phosphatase activity
JAV55_RS18915	COG3944	biosynthesis protein
JAV55_RS18925	COG4715	Zinc finger, swim domain protein
JAV55_RS18930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JAV55_RS18935	COG0561	phosphatase activity
JAV55_RS18940	COG1349	DNA-binding transcription factor activity
JAV55_RS18950	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS18960	COG3732	PTS system glucitol sorbitol-specific
JAV55_RS18980	COG0629	single-stranded DNA binding
JAV55_RS18995	COG1970	mechanosensitive ion channel activity
JAV55_RS19000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JAV55_RS19005	COG4786	Flagellar basal body rod
JAV55_RS19010	COG4786	Flagellar basal body rod
JAV55_RS19015	COG1077	Cell shape determining protein MreB Mrl
JAV55_RS19020	COG1609	Transcriptional regulator
JAV55_RS19025	COG1846	Transcriptional regulator
JAV55_RS19030	COG2814	Major facilitator Superfamily
JAV55_RS19035	COG0671	phosphoesterase, PA-phosphatase related
JAV55_RS19040	COG1227	inorganic diphosphatase activity
JAV55_RS19045	COG3546	catalase activity
JAV55_RS19050	COG3361	conserved protein (COG2071)
JAV55_RS19055	COG0517	IMP dehydrogenase activity
JAV55_RS19060	COG0598	Magnesium transport protein CorA
JAV55_RS19065	COG1253	flavin adenine dinucleotide binding
JAV55_RS19070	COG0004	ammonium transporteR
JAV55_RS19075	COG0347	Belongs to the P(II) protein family
JAV55_RS19080	COG0740	serine-type endopeptidase activity
JAV55_RS19090	COG0739	heme binding
JAV55_RS19095	COG1247	-acetyltransferase
JAV55_RS19105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JAV55_RS19115	COG0477	Major facilitator Superfamily
JAV55_RS19120	COG3251	PFAM MbtH domain protein
JAV55_RS19125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_RS19130	COG3433	isochorismatase activity
JAV55_RS19130	COG1535	isochorismatase
JAV55_RS19135	COG1021	2,3-dihydroxybenzoate-AMP ligase
JAV55_RS19140	COG1169	isochorismate synthase
JAV55_RS19145	COG1028	Short-chain dehydrogenase reductase Sdr
JAV55_RS19150	COG2819	hydrolase of the alpha beta superfamily
JAV55_RS19155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS19160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JAV55_RS19165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS19170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS19170	COG2207	Transcriptional regulator
JAV55_RS19180	COG2910	NAD(P)H-binding
JAV55_RS19185	COG1959	2 iron, 2 sulfur cluster binding
JAV55_RS19195	COG1994	Peptidase M50
JAV55_RS19200	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JAV55_RS19205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JAV55_RS19210	COG2223	nitrite transmembrane transporter activity
JAV55_RS19215	COG0243	molybdopterin cofactor binding
JAV55_RS19220	COG2304	oxidoreductase activity
JAV55_RS19225	COG2304	oxidoreductase activity
JAV55_RS19230	COG2385	sporulation resulting in formation of a cellular spore
JAV55_RS19235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JAV55_RS19245	COG4836	Membrane
JAV55_RS19250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JAV55_RS19255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JAV55_RS19260	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JAV55_RS19265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JAV55_RS19270	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JAV55_RS19275	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JAV55_RS19280	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JAV55_RS19295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JAV55_RS19300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JAV55_RS19305	COG4475	Protein of unknown function (DUF436)
JAV55_RS19310	COG0698	ribose 5-phosphate isomerase
JAV55_RS19315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JAV55_RS19320	COG1971	Probably functions as a manganese efflux pump
JAV55_RS19325	COG0009	L-threonylcarbamoyladenylate synthase
JAV55_RS19330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JAV55_RS19340	COG0738	Major facilitator superfamily
JAV55_RS19345	COG0673	inositol 2-dehydrogenase activity
JAV55_RS19350	COG0561	phosphatase activity
JAV55_RS19355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JAV55_RS19360	COG1609	Transcriptional regulator
JAV55_RS19365	COG2890	protein-(glutamine-N5) methyltransferase activity
JAV55_RS19370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JAV55_RS19375	COG0346	lactoylglutathione lyase activity
JAV55_RS19380	COG0789	Transcriptional regulator
JAV55_RS19385	COG0679	Auxin Efflux Carrier
JAV55_RS19390	COG0281	malic enzyme
JAV55_RS19395	COG1435	thymidine kinase activity
JAV55_RS19400	COG0254	rRNA binding
JAV55_RS19405	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JAV55_RS19410	COG1494	fructose-1,6-bisphosphatase
JAV55_RS19415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JAV55_RS19420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JAV55_RS19425	COG0191	fructose-bisphosphate aldolase activity
JAV55_RS19430	COG2204	response regulator
JAV55_RS19435	COG4821	SIS domain
JAV55_RS19440	COG0504	CTP synthase activity
JAV55_RS19445	COG3343	RNA polymerase activity
JAV55_RS19455	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS19460	COG1960	acyl-CoA dehydrogenase activity
JAV55_RS19465	COG1250	3-hydroxyacyl-CoA dehydrogenase
JAV55_RS19470	COG0183	Belongs to the thiolase family
JAV55_RS19475	COG0247	lactate metabolic process
JAV55_RS19475	COG2181	nitrate reductase activity
JAV55_RS19480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JAV55_RS19490	COG0018	arginyl-trna synthetase
JAV55_RS19495	COG4506	Protein conserved in bacteria
JAV55_RS19500	COG0010	Belongs to the arginase family
JAV55_RS19505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JAV55_RS19520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JAV55_RS19530	COG1994	Peptidase M50
JAV55_RS19535	COG1942	4-Oxalocrotonate Tautomerase
JAV55_RS19545	COG3465	dGTPase activity
JAV55_RS19550	COG1078	dGTPase activity
JAV55_RS19555	COG4844	belongs to the
JAV55_RS19580	COG2814	Major facilitator Superfamily
JAV55_RS19605	COG1414	Transcriptional regulator
JAV55_RS19615	COG0280	phosphate acetyltransferase
JAV55_RS19620	COG3253	May function as heme-dependent peroxidase
JAV55_RS19630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JAV55_RS19650	COG1131	(ABC) transporter
JAV55_RS19665	COG2363	Small membrane protein
JAV55_RS19670	COG2233	PERMEase
JAV55_RS19680	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS19685	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JAV55_RS19690	COG1216	Glycosyl transferase, family 2
JAV55_RS19695	COG0351	phosphomethylpyrimidine kinase
JAV55_RS19705	COG1621	beta-fructofuranosidase activity
JAV55_RS19710	COG1263	PTS System
JAV55_RS19710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS19715	COG3711	transcriptional antiterminator
JAV55_RS19725	COG1404	Belongs to the peptidase S8 family
JAV55_RS19735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JAV55_RS19740	COG0778	Nitroreductase
JAV55_RS19745	COG1473	amidohydrolase
JAV55_RS19750	COG0772	Belongs to the SEDS family
JAV55_RS19755	COG0772	Belongs to the SEDS family
JAV55_RS19760	COG3314	Sporulation integral membrane protein YlbJ
JAV55_RS19775	COG0456	acetyltransferase
JAV55_RS19810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JAV55_RS19820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JAV55_RS19825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JAV55_RS19830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_RS19845	COG3162	membrane
JAV55_RS19850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS19855	COG1070	Carbohydrate kinase
JAV55_RS19860	COG2115	Belongs to the xylose isomerase family
JAV55_RS19870	COG0352	thiamine-phosphate diphosphorylase activity
JAV55_RS19875	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JAV55_RS19880	COG0583	DNA-binding transcription factor activity
JAV55_RS19895	COG1380	Effector of murein hydrolase LrgA
JAV55_RS19900	COG1346	cytolysis
JAV55_RS19910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JAV55_RS19915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JAV55_RS19920	COG0346	lactoylglutathione lyase activity
JAV55_RS19925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JAV55_RS19930	COG1442	glycosyl transferase family 8
JAV55_RS19940	COG4585	Histidine kinase
JAV55_RS19945	COG2197	response regulator
JAV55_RS19950	COG2409	Drug exporters of the RND superfamily
JAV55_RS19955	COG5522	Integral membrane protein (intg_mem_TP0381)
JAV55_RS19960	COG2271	Major facilitator Superfamily
JAV55_RS19965	COG4948	Mandelate Racemase Muconate Lactonizing
JAV55_RS19970	COG0800	Aldolase
JAV55_RS19975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_RS19985	COG2234	aminopeptidase activity
JAV55_RS19990	COG0477	Major facilitator Superfamily
JAV55_RS20000	COG2357	RelA SpoT domain protein
JAV55_RS20015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JAV55_RS20020	COG1696	Membrane protein involved in D-alanine export
JAV55_RS20025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JAV55_RS20030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JAV55_RS20035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JAV55_RS20040	COG2814	Major facilitator Superfamily
JAV55_RS20045	COG1486	melibiose metabolic process
JAV55_RS20050	COG1447	Phosphotransferase system cellobiose-specific component IIA
JAV55_RS20055	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS20060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS20065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JAV55_RS20065	COG3711	transcriptional antiterminator
JAV55_RS20070	COG2094	Belongs to the DNA glycosylase MPG family
JAV55_RS20080	COG0372	Belongs to the citrate synthase family
JAV55_RS20085	COG2079	MmgE PrpD family protein
JAV55_RS20090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JAV55_RS20105	COG1132	(ABC) transporter
JAV55_RS20110	COG2755	lipolytic protein G-D-S-L family
JAV55_RS20125	COG2814	Major facilitator Superfamily
JAV55_RS20130	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_RS20135	COG1131	(ABC) transporter
JAV55_RS20155	COG1595	DNA-templated transcription, initiation
JAV55_RS20160	COG2814	Major facilitator Superfamily
JAV55_RS20165	COG0753	catalase activity
JAV55_RS20170	COG0753	catalase activity
JAV55_RS20175	COG0735	belongs to the Fur family
JAV55_RS20180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JAV55_RS20185	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JAV55_RS20190	COG1131	(ABC) transporter
JAV55_RS20205	COG1131	(ABC) transporter
JAV55_RS20260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JAV55_RS20265	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JAV55_RS20270	COG4988	ABC transporter
JAV55_RS20275	COG1294	oxidase, subunit
JAV55_RS20280	COG1271	oxidase subunit
JAV55_RS20285	COG2116	formate transmembrane transporter activity
JAV55_RS20295	COG0281	malic enzyme
JAV55_RS20300	COG1757	Na H antiporter
JAV55_RS20305	COG1027	Aspartate ammonia-lyase
JAV55_RS20310	COG0252	asparaginase activity
JAV55_RS20315	COG1396	sequence-specific DNA binding
JAV55_RS20320	COG2706	6-phosphogluconolactonase activity
JAV55_RS20325	COG0745	RESPONSE REGULATOR receiver
JAV55_RS20330	COG2205	protein histidine kinase activity
JAV55_RS20335	COG1136	(ABC) transporter
JAV55_RS20345	COG5294	Protein conserved in bacteria
JAV55_RS20360	COG0726	polysaccharide deacetylase
JAV55_RS20365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JAV55_RS20370	COG1215	transferase activity, transferring glycosyl groups
JAV55_RS20375	COG3493	citrate carrier protein
JAV55_RS20380	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_RS20395	COG1368	sulfuric ester hydrolase activity
JAV55_RS20405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JAV55_RS20415	COG2235	arginine
JAV55_RS20420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JAV55_RS20430	COG0549	Belongs to the carbamate kinase family
JAV55_RS20445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JAV55_RS20455	COG1595	DNA-templated transcription, initiation
JAV55_RS20470	COG2195	Cleaves the N-terminal amino acid of tripeptides
JAV55_RS20475	COG1621	beta-fructofuranosidase activity
JAV55_RS20480	COG2223	nitrite transmembrane transporter activity
JAV55_RS20485	COG1609	Transcriptional regulator
JAV55_RS20500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JAV55_RS20505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JAV55_RS20510	COG0463	Glycosyl transferase, family 2
JAV55_RS20515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_RS20540	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_RS20545	COG0753	catalase activity
JAV55_RS20545	COG0693	protein deglycase activity
JAV55_RS20555	COG2723	6-phospho-beta-galactosidase activity
JAV55_RS20560	COG1263	PTS System
JAV55_RS20560	COG2190	(PTS) system
JAV55_RS20560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS20570	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JAV55_RS20575	COG1122	ATPase activity
JAV55_RS20580	COG4721	ABC-type cobalt transport system, permease component
JAV55_RS20585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JAV55_RS20595	COG2224	Isocitrate lyase
JAV55_RS20600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JAV55_RS20610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JAV55_RS20615	COG0577	efflux transmembrane transporter activity
JAV55_RS20620	COG1136	(ABC) transporter
JAV55_RS20625	COG2205	protein histidine kinase activity
JAV55_RS20630	COG0745	RESPONSE REGULATOR receiver
JAV55_RS20635	COG2723	6-phospho-beta-galactosidase activity
JAV55_RS20640	COG1263	PTS System
JAV55_RS20640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS20640	COG2190	(PTS) system
JAV55_RS20650	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JAV55_RS20665	COG3507	Belongs to the glycosyl hydrolase 43 family
JAV55_RS20670	COG0513	Belongs to the DEAD box helicase family
JAV55_RS20700	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JAV55_RS20705	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JAV55_RS20710	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JAV55_RS20715	COG2390	Transcriptional regulator
JAV55_RS20725	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JAV55_RS20730	COG3706	GGDEF domain
JAV55_RS20735	COG5298	Protein conserved in bacteria
JAV55_RS20740	COG1215	transferase activity, transferring glycosyl groups
JAV55_RS20750	COG3977	Valine--pyruvate aminotransferase
JAV55_RS20765	COG1181	Belongs to the D-alanine--D-alanine ligase family
JAV55_RS20775	COG0191	fructose-bisphosphate aldolase activity
JAV55_RS20780	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_RS20785	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_RS20790	COG0673	inositol 2-dehydrogenase activity
JAV55_RS20795	COG2814	Major facilitator Superfamily
JAV55_RS20800	COG1082	Xylose isomerase domain protein TIM barrel
JAV55_RS20805	COG3962	Belongs to the TPP enzyme family
JAV55_RS20810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JAV55_RS20815	COG3718	enzyme involved in inositol metabolism
JAV55_RS20820	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS20825	COG1349	DNA-binding transcription factor activity
JAV55_RS20830	COG0667	Aldo Keto reductase
JAV55_RS20835	COG0584	glycerophosphoryl diester phosphodiesterase
JAV55_RS20840	COG2271	Major facilitator Superfamily
JAV55_RS20845	COG0326	Molecular chaperone. Has ATPase activity
JAV55_RS20850	COG0488	(ABC) transporter
JAV55_RS20855	COG0561	phosphatase activity
JAV55_RS20875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JAV55_RS20905	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JAV55_RS20910	COG0577	efflux transmembrane transporter activity
JAV55_RS20915	COG1136	(ABC) transporter
JAV55_RS20920	COG2205	protein histidine kinase activity
JAV55_RS20925	COG0745	RESPONSE REGULATOR receiver
JAV55_RS20935	COG5278	phosphoserine phosphatase activity
JAV55_RS20935	COG0840	transmembrane signaling receptor activity
JAV55_RS20940	COG1115	amino acid carrier protein
JAV55_RS20945	COG0686	Belongs to the AlaDH PNT family
JAV55_RS20950	COG3867	Arabinogalactan endo-beta-1,4-galactanase
JAV55_RS20955	COG1874	Beta-galactosidase
JAV55_RS20960	COG3833	ABC-type maltose transport systems, permease component
JAV55_RS20965	COG1175	transmembrane transport
JAV55_RS20970	COG2182	Extracellular solute-binding protein
JAV55_RS20975	COG1609	Transcriptional regulator
JAV55_RS20985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JAV55_RS20990	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JAV55_RS20995	COG1940	carbohydrate kinase activity
JAV55_RS21020	COG1454	alcohol dehydrogenase
JAV55_RS21020	COG1012	belongs to the aldehyde dehydrogenase family
JAV55_RS21025	COG0450	alkyl hydroperoxide reductase
JAV55_RS21030	COG3634	alkyl hydroperoxide reductase activity
JAV55_RS21055	COG1131	(ABC) transporter
JAV55_RS21060	COG0842	Transport permease protein
JAV55_RS21065	COG4585	Histidine kinase
JAV55_RS21070	COG2197	response regulator
JAV55_RS21100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JAV55_RS21115	COG0456	acetyltransferase
JAV55_RS21130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JAV55_RS21135	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JAV55_RS21140	COG4853	Protein conserved in bacteria
JAV55_RS21145	COG4863	YycH protein
JAV55_RS21150	COG5002	protein histidine kinase activity
JAV55_RS21155	COG0745	RESPONSE REGULATOR receiver
JAV55_RS21180	COG1051	belongs to the nudix hydrolase family
JAV55_RS21185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JAV55_RS21195	COG0305	Participates in initiation and elongation during chromosome replication
JAV55_RS21210	COG3093	addiction module antidote protein HigA
JAV55_RS21215	COG2807	transmembrane transport
JAV55_RS21220	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JAV55_RS21225	COG0363	glucosamine-6-phosphate deaminase activity
JAV55_RS21230	COG2188	Transcriptional regulator
JAV55_RS21235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JAV55_RS21240	COG1263	PTS System
JAV55_RS21240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JAV55_RS21245	COG0359	binds to the 23S rRNA
JAV55_RS21250	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JAV55_RS21255	COG4241	membrane
JAV55_RS21265	COG5577	PFAM Coat F domain
JAV55_RS21270	COG0589	response to stress
JAV55_RS21275	COG0659	secondary active sulfate transmembrane transporter activity
JAV55_RS21280	COG2271	Major facilitator Superfamily
JAV55_RS21285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JAV55_RS21290	COG0629	single-stranded DNA binding
JAV55_RS21295	COG0360	Binds together with S18 to 16S ribosomal RNA
JAV55_RS21300	COG0012	GTP binding
JAV55_RS21305	COG4481	Protein conserved in bacteria
JAV55_RS21310	COG3949	Membrane
JAV55_RS21320	COG1475	DNA binding
JAV55_RS21325	COG1192	Involved in chromosome partitioning
JAV55_RS21330	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JAV55_RS21340	COG1475	DNA binding
JAV55_RS21345	COG0357	Ribosomal RNA small subunit methyltransferase G
JAV55_RS21350	COG0445	tRNA wobble uridine modification
JAV55_RS21355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JAV55_RS21360	COG1847	R3H domain protein
JAV55_RS21365	COG0706	membrane insertase activity
JAV55_RS21370	COG0594	ribonuclease P activity