locus-tag	class	description
EYQ98_RS00025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ98_RS00040	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS00045	COG2190	(PTS) system
EYQ98_RS00045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS00045	COG1263	PTS System
EYQ98_RS00050	COG3711	transcriptional antiterminator
EYQ98_RS00055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYQ98_RS00065	COG4721	ABC-type cobalt transport system, permease component
EYQ98_RS00070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EYQ98_RS00075	COG2224	Isocitrate lyase
EYQ98_RS00080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EYQ98_RS00095	COG0577	efflux transmembrane transporter activity
EYQ98_RS00100	COG1136	(ABC) transporter
EYQ98_RS00105	COG2205	protein histidine kinase activity
EYQ98_RS00110	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS00115	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS00120	COG2190	(PTS) system
EYQ98_RS00120	COG1263	PTS System
EYQ98_RS00120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS00130	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EYQ98_RS00135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYQ98_RS00140	COG3507	Belongs to the glycosyl hydrolase 43 family
EYQ98_RS00145	COG0513	Belongs to the DEAD box helicase family
EYQ98_RS00175	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EYQ98_RS00180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ98_RS00185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYQ98_RS00190	COG2390	Transcriptional regulator
EYQ98_RS00200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EYQ98_RS00205	COG3706	GGDEF domain
EYQ98_RS00210	COG5298	Protein conserved in bacteria
EYQ98_RS00215	COG1215	transferase activity, transferring glycosyl groups
EYQ98_RS00225	COG3977	Valine--pyruvate aminotransferase
EYQ98_RS00240	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYQ98_RS00250	COG0191	fructose-bisphosphate aldolase activity
EYQ98_RS00255	COG1082	Xylose isomerase domain protein TIM barrel
EYQ98_RS00260	COG1082	Xylose isomerase domain protein TIM barrel
EYQ98_RS00265	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS00270	COG2814	Major facilitator Superfamily
EYQ98_RS00275	COG1082	Xylose isomerase domain protein TIM barrel
EYQ98_RS00280	COG3962	Belongs to the TPP enzyme family
EYQ98_RS00285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYQ98_RS00290	COG3718	enzyme involved in inositol metabolism
EYQ98_RS00295	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS00300	COG1349	DNA-binding transcription factor activity
EYQ98_RS00305	COG0667	Aldo Keto reductase
EYQ98_RS00310	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ98_RS00315	COG2271	Major facilitator Superfamily
EYQ98_RS00320	COG0326	Molecular chaperone. Has ATPase activity
EYQ98_RS00325	COG0488	(ABC) transporter
EYQ98_RS00330	COG0561	phosphatase activity
EYQ98_RS00350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS00380	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EYQ98_RS00385	COG0577	efflux transmembrane transporter activity
EYQ98_RS00390	COG1136	(ABC) transporter
EYQ98_RS00395	COG2205	protein histidine kinase activity
EYQ98_RS00400	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS00410	COG0840	transmembrane signaling receptor activity
EYQ98_RS00410	COG5278	phosphoserine phosphatase activity
EYQ98_RS00415	COG1115	amino acid carrier protein
EYQ98_RS00420	COG0686	Belongs to the AlaDH PNT family
EYQ98_RS00425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EYQ98_RS00430	COG1874	Beta-galactosidase
EYQ98_RS00435	COG3833	ABC-type maltose transport systems, permease component
EYQ98_RS00440	COG1175	transmembrane transport
EYQ98_RS00445	COG2182	Extracellular solute-binding protein
EYQ98_RS00450	COG1609	Transcriptional regulator
EYQ98_RS00460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYQ98_RS00465	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EYQ98_RS00470	COG1940	carbohydrate kinase activity
EYQ98_RS00495	COG1454	alcohol dehydrogenase
EYQ98_RS00495	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS00500	COG0450	alkyl hydroperoxide reductase
EYQ98_RS00505	COG3634	alkyl hydroperoxide reductase activity
EYQ98_RS00530	COG1131	(ABC) transporter
EYQ98_RS00535	COG0842	Transport permease protein
EYQ98_RS00540	COG4585	Histidine kinase
EYQ98_RS00545	COG2197	response regulator
EYQ98_RS00600	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EYQ98_RS00645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYQ98_RS00650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYQ98_RS00665	COG0456	acetyltransferase
EYQ98_RS00680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYQ98_RS00685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYQ98_RS00690	COG4853	Protein conserved in bacteria
EYQ98_RS00695	COG4863	YycH protein
EYQ98_RS00700	COG5002	protein histidine kinase activity
EYQ98_RS00705	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS00730	COG1051	belongs to the nudix hydrolase family
EYQ98_RS00735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYQ98_RS00745	COG0305	Participates in initiation and elongation during chromosome replication
EYQ98_RS00760	COG3093	addiction module antidote protein HigA
EYQ98_RS00765	COG2807	transmembrane transport
EYQ98_RS00770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYQ98_RS00775	COG0363	glucosamine-6-phosphate deaminase activity
EYQ98_RS00780	COG2188	Transcriptional regulator
EYQ98_RS00785	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EYQ98_RS00790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS00790	COG1263	PTS System
EYQ98_RS00795	COG0359	binds to the 23S rRNA
EYQ98_RS00800	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EYQ98_RS00805	COG4241	membrane
EYQ98_RS00810	COG5577	PFAM Coat F domain
EYQ98_RS00815	COG0589	response to stress
EYQ98_RS00820	COG0659	secondary active sulfate transmembrane transporter activity
EYQ98_RS00825	COG2271	Major facilitator Superfamily
EYQ98_RS00830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYQ98_RS00835	COG0629	single-stranded DNA binding
EYQ98_RS00840	COG0360	Binds together with S18 to 16S ribosomal RNA
EYQ98_RS00845	COG0012	GTP binding
EYQ98_RS00855	COG4481	Protein conserved in bacteria
EYQ98_RS00860	COG3949	Membrane
EYQ98_RS00870	COG1475	DNA binding
EYQ98_RS00875	COG1192	Involved in chromosome partitioning
EYQ98_RS00880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYQ98_RS00890	COG1475	DNA binding
EYQ98_RS00895	COG0357	Ribosomal RNA small subunit methyltransferase G
EYQ98_RS00900	COG0445	tRNA wobble uridine modification
EYQ98_RS00905	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYQ98_RS00910	COG1847	R3H domain protein
EYQ98_RS00915	COG0706	membrane insertase activity
EYQ98_RS00920	COG0594	ribonuclease P activity
EYQ98_RS00930	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYQ98_RS00935	COG0592	DNA-directed DNA polymerase activity
EYQ98_RS00940	COG2501	S4 domain
EYQ98_RS00945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYQ98_RS00955	COG0187	DNA topoisomerase II activity
EYQ98_RS00960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYQ98_RS00995	COG0516	GMP reductase activity
EYQ98_RS00995	COG0517	IMP dehydrogenase activity
EYQ98_RS01000	COG1686	Belongs to the peptidase S11 family
EYQ98_RS01005	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EYQ98_RS01010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EYQ98_RS01015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYQ98_RS01020	COG1929	Belongs to the glycerate kinase type-1 family
EYQ98_RS01025	COG2610	gluconate transmembrane transporter activity
EYQ98_RS01030	COG3835	regulator
EYQ98_RS01045	COG1428	Deoxynucleoside kinase
EYQ98_RS01050	COG1428	Deoxynucleoside kinase
EYQ98_RS01055	COG3858	chitin binding
EYQ98_RS01055	COG1388	LysM domain
EYQ98_RS01060	COG1335	isochorismatase
EYQ98_RS01065	COG0590	tRNA wobble adenosine to inosine editing
EYQ98_RS01075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYQ98_RS01080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYQ98_RS01085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYQ98_RS01130	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EYQ98_RS01135	COG3853	Toxic anion resistance protein (TelA)
EYQ98_RS01140	COG1982	Orn Lys Arg decarboxylase major
EYQ98_RS01145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYQ98_RS01150	COG3870	Protein conserved in bacteria
EYQ98_RS01155	COG1728	Protein conserved in bacteria
EYQ98_RS01160	COG0470	DNA polymerase III
EYQ98_RS01165	COG1774	PSP1 C-terminal conserved region
EYQ98_RS01170	COG4467	Involved in initiation control of chromosome replication
EYQ98_RS01175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYQ98_RS01180	COG2827	Endonuclease containing a URI domain
EYQ98_RS01185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYQ98_RS01190	COG2002	toxin-antitoxin pair type II binding
EYQ98_RS01195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ98_RS01195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ98_RS01200	COG0084	hydrolase, TatD family'
EYQ98_RS01205	COG3583	domain protein
EYQ98_RS01205	COG3584	3D domain protein
EYQ98_RS01210	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYQ98_RS01215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYQ98_RS01225	COG4466	Protein conserved in bacteria
EYQ98_RS01235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYQ98_RS01240	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYQ98_RS01245	COG0251	oxidation-reduction process
EYQ98_RS01250	COG2088	sporulation resulting in formation of a cellular spore
EYQ98_RS01255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYQ98_RS01260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYQ98_RS01265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYQ98_RS01270	COG0193	aminoacyl-tRNA hydrolase activity
EYQ98_RS01280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYQ98_RS01285	COG2002	toxin-antitoxin pair type II binding
EYQ98_RS01290	COG2244	polysaccharide biosynthetic process
EYQ98_RS01295	COG3956	TIGRFAM MazG family protein
EYQ98_RS01300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYQ98_RS01315	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EYQ98_RS01320	COG1098	S1 RNA binding domain
EYQ98_RS01335	COG2208	phosphoserine phosphatase activity
EYQ98_RS01340	COG2304	oxidoreductase activity
EYQ98_RS01345	COG0515	serine threonine protein kinase
EYQ98_RS01350	COG0037	tRNA processing
EYQ98_RS01355	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EYQ98_RS01360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYQ98_RS01365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYQ98_RS01370	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYQ98_RS01375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYQ98_RS01380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYQ98_RS01390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYQ98_RS01395	COG0512	Glutamine amidotransferase of anthranilate synthase
EYQ98_RS01400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYQ98_RS01405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYQ98_RS01410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYQ98_RS01415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYQ98_RS01420	COG1396	sequence-specific DNA binding
EYQ98_RS01425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYQ98_RS01430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYQ98_RS01510	COG4463	regulation of RNA biosynthetic process
EYQ98_RS01515	COG3880	PFAM UvrB UvrC protein
EYQ98_RS01520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EYQ98_RS01525	COG0542	response to heat
EYQ98_RS01530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYQ98_RS01535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EYQ98_RS01540	COG4956	integral membrane protein (PIN domain superfamily)
EYQ98_RS01545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYQ98_RS01550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYQ98_RS01555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYQ98_RS01560	COG1045	serine acetyltransferase
EYQ98_RS01565	COG0215	cysteine-tRNA ligase activity
EYQ98_RS01570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EYQ98_RS01575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYQ98_RS01580	COG3688	RNA-binding protein containing a PIN domain
EYQ98_RS01590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYQ98_RS01600	COG0250	Participates in transcription elongation, termination and antitermination
EYQ98_RS01605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYQ98_RS01610	COG0081	regulation of translation
EYQ98_RS01615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYQ98_RS01620	COG0222	ribosome binding
EYQ98_RS01625	COG2813	Specifically methylates the guanine in position
EYQ98_RS01630	COG0085	RNA polymerase activity
EYQ98_RS01635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYQ98_RS01640	COG1358	cellular component organization or biogenesis
EYQ98_RS01645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYQ98_RS01650	COG0049	tRNA binding
EYQ98_RS01655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYQ98_RS01660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYQ98_RS01670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYQ98_RS01675	COG0088	Forms part of the polypeptide exit tunnel
EYQ98_RS01680	COG0089	rRNA binding
EYQ98_RS01685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYQ98_RS01690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYQ98_RS01695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYQ98_RS01700	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYQ98_RS01705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYQ98_RS01710	COG0255	Belongs to the universal ribosomal protein uL29 family
EYQ98_RS01715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYQ98_RS01720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYQ98_RS01725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYQ98_RS01730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYQ98_RS01735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYQ98_RS01740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYQ98_RS01745	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYQ98_RS01750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYQ98_RS01755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYQ98_RS01760	COG1841	ribosomal large subunit assembly
EYQ98_RS01765	COG0200	Binds to the 23S rRNA
EYQ98_RS01770	COG0201	protein transport
EYQ98_RS01775	COG0563	adenylate kinase activity
EYQ98_RS01780	COG0024	Methionine aminopeptidase
EYQ98_RS01785	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EYQ98_RS01790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYQ98_RS01795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYQ98_RS01800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYQ98_RS01805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYQ98_RS01810	COG0202	RNA polymerase activity
EYQ98_RS01815	COG0203	ribosomal protein L17
EYQ98_RS01820	COG1122	ATPase activity
EYQ98_RS01825	COG1122	ATPase activity
EYQ98_RS01830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYQ98_RS01835	COG0101	tRNA pseudouridine synthase activity
EYQ98_RS01840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYQ98_RS01845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYQ98_RS01850	COG2318	DinB family
EYQ98_RS01860	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS01865	COG0489	protein tyrosine kinase activity
EYQ98_RS01875	COG2194	sulfuric ester hydrolase activity
EYQ98_RS01880	COG0726	polysaccharide deacetylase
EYQ98_RS01910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYQ98_RS01920	COG0385	Bile acid
EYQ98_RS01935	COG3876	Protein conserved in bacteria
EYQ98_RS01940	COG1472	Belongs to the glycosyl hydrolase 3 family
EYQ98_RS01945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYQ98_RS01950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS01950	COG1263	PTS System
EYQ98_RS01955	COG1737	Transcriptional regulator
EYQ98_RS01960	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EYQ98_RS01965	COG1683	Conserved Protein
EYQ98_RS02000	COG1595	DNA-templated transcription, initiation
EYQ98_RS02005	COG5662	AntiSigma factor
EYQ98_RS02010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYQ98_RS02015	COG4856	YbbR-like protein
EYQ98_RS02020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYQ98_RS02025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYQ98_RS02045	COG1725	Transcriptional regulator
EYQ98_RS02050	COG0640	Transcriptional regulator
EYQ98_RS02055	COG2814	Major facilitator Superfamily
EYQ98_RS02065	COG1132	(ABC) transporter
EYQ98_RS02070	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYQ98_RS02095	COG1011	Hydrolase
EYQ98_RS02100	COG1113	amino acid transport
EYQ98_RS02105	COG2851	Citrate transporter
EYQ98_RS02110	COG3181	Tripartite tricarboxylate transporter family receptor
EYQ98_RS02115	COG4565	transcriptional regulatory protein
EYQ98_RS02120	COG3290	protein histidine kinase activity
EYQ98_RS02155	COG1331	Highly conserved protein containing a thioredoxin domain
EYQ98_RS02160	COG3677	Transposase
EYQ98_RS02200	COG1331	Highly conserved protein containing a thioredoxin domain
EYQ98_RS02210	COG0477	Major facilitator Superfamily
EYQ98_RS02230	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYQ98_RS02235	COG4682	membrane
EYQ98_RS02260	COG0697	spore germination
EYQ98_RS02265	COG1917	Cupin 2, conserved barrel domain protein
EYQ98_RS02265	COG2207	Transcriptional regulator
EYQ98_RS02285	COG0371	Dehydrogenase
EYQ98_RS02290	COG0840	transmembrane signaling receptor activity
EYQ98_RS02295	COG4213	ABC transporter substrate-binding protein
EYQ98_RS02310	COG4257	antibiotic catabolic process
EYQ98_RS02320	COG0833	amino acid
EYQ98_RS02325	COG2040	homocysteine
EYQ98_RS02335	COG1263	PTS System
EYQ98_RS02335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS02335	COG2190	(PTS) system
EYQ98_RS02340	COG0789	Transcriptional regulator
EYQ98_RS02345	COG2323	membrane
EYQ98_RS02350	COG4451	ribulose bisphosphate carboxylase, small
EYQ98_RS02350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYQ98_RS02360	COG2205	protein histidine kinase activity
EYQ98_RS02365	COG1115	amino acid carrier protein
EYQ98_RS02370	COG2066	Belongs to the glutaminase family
EYQ98_RS02375	COG4191	Histidine kinase
EYQ98_RS02380	COG0784	Response regulator, receiver
EYQ98_RS02405	COG3540	Alkaline phosphatase
EYQ98_RS02410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYQ98_RS02415	COG0805	protein transport
EYQ98_RS02420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYQ98_RS02425	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS02430	COG2271	Major facilitator Superfamily
EYQ98_RS02440	COG2186	Transcriptional regulator
EYQ98_RS02445	COG2721	sulfolactate sulfo-lyase activity
EYQ98_RS02450	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS02455	COG2205	protein histidine kinase activity
EYQ98_RS02460	COG1131	(ABC) transporter
EYQ98_RS02485	COG3173	Aminoglycoside phosphotransferase
EYQ98_RS02490	COG1846	Transcriptional regulator
EYQ98_RS02495	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS02515	COG0789	Transcriptional regulator
EYQ98_RS02540	COG0697	spore germination
EYQ98_RS02545	COG1714	RDD family
EYQ98_RS02550	COG3012	SEC-C Motif Domain Protein
EYQ98_RS02550	COG1405	negative regulation of cell septum assembly
EYQ98_RS02555	COG1131	(ABC) transporter
EYQ98_RS02585	COG1942	4-Oxalocrotonate Tautomerase
EYQ98_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS02605	COG1288	antiporter activity
EYQ98_RS02615	COG0456	acetyltransferase
EYQ98_RS02625	COG1164	Oligoendopeptidase f
EYQ98_RS02630	COG2261	transglycosylase associated protein
EYQ98_RS02640	COG0247	lactate metabolic process
EYQ98_RS02650	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS02655	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYQ98_RS02660	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS02665	COG1486	melibiose metabolic process
EYQ98_RS02670	COG2188	Transcriptional regulator
EYQ98_RS02675	COG3394	polysaccharide catabolic process
EYQ98_RS02690	COG3591	Belongs to the peptidase S1B family
EYQ98_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS02705	COG1595	DNA-templated transcription, initiation
EYQ98_RS02715	COG3773	Cell wall hydrolase
EYQ98_RS02720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ98_RS02725	COG0791	NLP P60 protein
EYQ98_RS02725	COG3883	PFAM NLP P60 protein
EYQ98_RS02735	COG1131	(ABC) transporter
EYQ98_RS02740	COG1309	transcriptional regulator
EYQ98_RS02765	COG2310	stress, protein
EYQ98_RS02770	COG2310	stress, protein
EYQ98_RS02775	COG0861	Integral membrane protein TerC family
EYQ98_RS02795	COG3853	Toxic anion resistance protein (TelA)
EYQ98_RS02800	COG0785	Cytochrome C biogenesis protein
EYQ98_RS02810	COG0789	Transcriptional regulator
EYQ98_RS02815	COG2223	nitrite transmembrane transporter activity
EYQ98_RS02820	COG0039	L-malate dehydrogenase activity
EYQ98_RS02825	COG1620	l-lactate permease
EYQ98_RS02830	COG1280	lysine exporter protein (LysE YggA)
EYQ98_RS02835	COG1113	amino acid transport
EYQ98_RS02840	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EYQ98_RS02845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYQ98_RS02850	COG3541	Predicted nucleotidyltransferase
EYQ98_RS02855	COG0506	proline dehydrogenase activity
EYQ98_RS02860	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS02865	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ98_RS02870	COG2508	Transcriptional regulator
EYQ98_RS02875	COG3689	TIGRFAM TIGR03943 family protein
EYQ98_RS02880	COG0701	Predicted permease
EYQ98_RS02885	COG3458	cephalosporin-C deacetylase activity
EYQ98_RS02905	COG0765	amino acid transport
EYQ98_RS02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYQ98_RS02915	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS02925	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS02935	COG3209	COG3209 Rhs family protein
EYQ98_RS02945	COG0515	serine threonine protein kinase
EYQ98_RS02945	COG3266	domain, Protein
EYQ98_RS02950	COG0840	transmembrane signaling receptor activity
EYQ98_RS02950	COG3290	protein histidine kinase activity
EYQ98_RS02955	COG5444	nuclease activity
EYQ98_RS02980	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYQ98_RS02985	COG1177	transmembrane transport
EYQ98_RS02995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYQ98_RS03000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYQ98_RS03005	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EYQ98_RS03010	COG0697	spore germination
EYQ98_RS03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYQ98_RS03025	COG2819	hydrolase of the alpha beta superfamily
EYQ98_RS03035	COG2364	Membrane
EYQ98_RS03045	COG1131	(ABC) transporter
EYQ98_RS03070	COG1126	abc transporter atp-binding protein
EYQ98_RS03075	COG0765	amino acid transport
EYQ98_RS03080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYQ98_RS03085	COG3829	transcription factor binding
EYQ98_RS03090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYQ98_RS03095	COG0833	amino acid
EYQ98_RS03100	COG0010	Belongs to the arginase family
EYQ98_RS03105	COG0583	DNA-binding transcription factor activity
EYQ98_RS03110	COG0163	prenyltransferase activity
EYQ98_RS03115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYQ98_RS03165	COG5444	nuclease activity
EYQ98_RS03185	COG2972	Histidine kinase
EYQ98_RS03190	COG4753	response regulator
EYQ98_RS03190	COG2207	Transcriptional regulator
EYQ98_RS03195	COG4213	ABC transporter substrate-binding protein
EYQ98_RS03205	COG4214	carbohydrate transport
EYQ98_RS03210	COG2271	Major facilitator Superfamily
EYQ98_RS03215	COG0456	acetyltransferase
EYQ98_RS03215	COG1846	Transcriptional regulator
EYQ98_RS03225	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EYQ98_RS03230	COG3104	oligopeptide transport
EYQ98_RS03235	COG5434	Belongs to the glycosyl hydrolase 28 family
EYQ98_RS03245	COG0697	spore germination
EYQ98_RS03255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EYQ98_RS03260	COG0789	Transcriptional regulator
EYQ98_RS03265	COG1136	(ABC) transporter
EYQ98_RS03270	COG0577	efflux transmembrane transporter activity
EYQ98_RS03275	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS03280	COG3850	Histidine kinase
EYQ98_RS03280	COG5002	protein histidine kinase activity
EYQ98_RS03290	COG0527	aspartate kinase activity
EYQ98_RS03295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS03300	COG4605	iron ion homeostasis
EYQ98_RS03305	COG4604	ABC transporter, ATP-binding protein
EYQ98_RS03310	COG4607	ABC-type enterochelin transport system periplasmic component
EYQ98_RS03315	COG2814	Major facilitator Superfamily
EYQ98_RS03320	COG1309	transcriptional regulator
EYQ98_RS03330	COG0778	Nitroreductase
EYQ98_RS03335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EYQ98_RS03340	COG0640	Transcriptional regulator
EYQ98_RS03345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYQ98_RS03350	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYQ98_RS03355	COG0531	amino acid
EYQ98_RS03360	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS03365	COG0697	spore germination
EYQ98_RS03375	COG4549	nuclear export factor GLE1
EYQ98_RS03380	COG2372	response to copper ion
EYQ98_RS03380	COG1276	copper resistance
EYQ98_RS03385	COG1349	DNA-binding transcription factor activity
EYQ98_RS03390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYQ98_RS03395	COG0243	molybdopterin cofactor binding
EYQ98_RS03400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYQ98_RS03405	COG2146	nitrite reductase [NAD(P)H] activity
EYQ98_RS03410	COG1587	Uroporphyrinogen-III synthase
EYQ98_RS03410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYQ98_RS03415	COG1802	Transcriptional regulator
EYQ98_RS03420	COG0471	metal ion transport
EYQ98_RS03425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYQ98_RS03430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYQ98_RS03445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS03460	COG3959	Transketolase, thiamine diphosphate binding domain
EYQ98_RS03465	COG3958	Transketolase
EYQ98_RS03470	COG0561	phosphatase activity
EYQ98_RS03475	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EYQ98_RS03480	COG1914	H( )-stimulated, divalent metal cation uptake system
EYQ98_RS03485	COG4336	lyase activity
EYQ98_RS03490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYQ98_RS03495	COG1984	allophanate hydrolase subunit 2
EYQ98_RS03500	COG1414	Transcriptional regulator
EYQ98_RS03505	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS03510	COG2213	PTS system mannitol-specific
EYQ98_RS03515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS03520	COG0246	Mannitol dehydrogenase
EYQ98_RS03525	COG3711	transcriptional antiterminator
EYQ98_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS03535	COG1917	Cupin 2, conserved barrel domain protein
EYQ98_RS03560	COG2814	Major facilitator Superfamily
EYQ98_RS03570	COG1522	sequence-specific DNA binding
EYQ98_RS03575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYQ98_RS03575	COG0551	DNA topoisomerase type I activity
EYQ98_RS03580	COG0531	amino acid
EYQ98_RS03585	COG0028	Belongs to the TPP enzyme family
EYQ98_RS03590	COG3397	chitin binding
EYQ98_RS03600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS03605	COG1914	H( )-stimulated, divalent metal cation uptake system
EYQ98_RS03610	COG2261	transglycosylase associated protein
EYQ98_RS03615	COG1027	Aspartate ammonia-lyase
EYQ98_RS03620	COG1819	glycosyl
EYQ98_RS03625	COG4876	unkown
EYQ98_RS03630	COG2217	Heavy metal translocating P-type atpase
EYQ98_RS03640	COG0662	Cupin 2, conserved barrel domain protein
EYQ98_RS03650	COG0628	permease
EYQ98_RS03655	COG1301	dicarboxylic acid transport
EYQ98_RS03660	COG1131	(ABC) transporter
EYQ98_RS03665	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYQ98_RS03675	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS03690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS03695	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYQ98_RS03700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYQ98_RS03710	COG0513	Belongs to the DEAD box helicase family
EYQ98_RS03715	COG3402	PFAM membrane-flanked domain
EYQ98_RS03720	COG3428	Bacterial PH domain
EYQ98_RS03725	COG0705	Rhomboid family
EYQ98_RS03730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYQ98_RS03735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYQ98_RS03740	COG0864	Transcriptional regulator
EYQ98_RS03745	COG2337	Toxic component of a toxin-antitoxin (TA) module
EYQ98_RS03750	COG1366	Belongs to the anti-sigma-factor antagonist family
EYQ98_RS03755	COG1366	Belongs to the anti-sigma-factor antagonist family
EYQ98_RS03760	COG2172	sigma factor antagonist activity
EYQ98_RS03765	COG2208	phosphoserine phosphatase activity
EYQ98_RS03775	COG2172	sigma factor antagonist activity
EYQ98_RS03780	COG1191	sigma factor activity
EYQ98_RS03785	COG2208	phosphoserine phosphatase activity
EYQ98_RS03790	COG2183	response to ionizing radiation
EYQ98_RS03795	COG1309	transcriptional regulator
EYQ98_RS03800	COG1033	growth of symbiont in host cell
EYQ98_RS03800	COG2409	Drug exporters of the RND superfamily
EYQ98_RS03810	COG3091	SprT-like family
EYQ98_RS03855	COG1476	TRANSCRIPTIONal
EYQ98_RS03860	COG3239	Fatty acid desaturase
EYQ98_RS03865	COG1278	Cold shock
EYQ98_RS03870	COG1063	alcohol dehydrogenase
EYQ98_RS03880	COG2364	Membrane
EYQ98_RS03885	COG1846	Transcriptional regulator
EYQ98_RS03890	COG0456	acetyltransferase
EYQ98_RS03895	COG2808	Putative FMN-binding domain
EYQ98_RS03905	COG1733	regulation of RNA biosynthetic process
EYQ98_RS03910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS03920	COG0583	DNA-binding transcription factor activity
EYQ98_RS03935	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EYQ98_RS03940	COG1113	amino acid transport
EYQ98_RS03955	COG1595	DNA-templated transcription, initiation
EYQ98_RS03965	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS03965	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYQ98_RS03970	COG2814	Major facilitator Superfamily
EYQ98_RS03975	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS03975	COG2972	Histidine kinase
EYQ98_RS03980	COG3279	Response regulator of the LytR AlgR family
EYQ98_RS03990	COG3764	Sortase (surface protein transpeptidase)
EYQ98_RS04000	COG2814	Major facilitator Superfamily
EYQ98_RS04040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EYQ98_RS04045	COG0802	atpase or kinase
EYQ98_RS04050	COG1214	PFAM Peptidase M22, glycoprotease
EYQ98_RS04055	COG0456	acetyltransferase
EYQ98_RS04060	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYQ98_RS04065	COG0488	(ABC) transporter
EYQ98_RS04070	COG0315	cyclic pyranopterin monophosphate synthase activity
EYQ98_RS04075	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EYQ98_RS04080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYQ98_RS04085	COG0805	protein transport
EYQ98_RS04095	COG1266	CAAX protease self-immunity
EYQ98_RS04100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYQ98_RS04105	COG0459	protein refolding
EYQ98_RS04135	COG2720	vancomycin resistance protein
EYQ98_RS04150	COG2135	peptidase activity
EYQ98_RS04160	COG1309	transcriptional regulator
EYQ98_RS04165	COG3848	Pyruvate phosphate dikinase
EYQ98_RS04165	COG0574	Belongs to the PEP-utilizing enzyme family
EYQ98_RS04175	COG3189	MarR family transcriptional regulator
EYQ98_RS04180	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EYQ98_RS04185	COG2272	Belongs to the type-B carboxylesterase lipase family
EYQ98_RS04190	COG2814	Major facilitator Superfamily
EYQ98_RS04195	COG1842	Phage shock protein A
EYQ98_RS04200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYQ98_RS04205	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EYQ98_RS04210	COG4260	virion core protein, lumpy skin disease virus
EYQ98_RS04220	COG1378	Sugar-specific transcriptional regulator TrmB
EYQ98_RS04225	COG1280	lysine exporter protein (LysE YggA)
EYQ98_RS04230	COG3339	Conserved Protein
EYQ98_RS04235	COG0772	Belongs to the SEDS family
EYQ98_RS04240	COG0772	Belongs to the SEDS family
EYQ98_RS04265	COG0726	polysaccharide deacetylase
EYQ98_RS04275	COG1609	Transcriptional regulator
EYQ98_RS04280	COG0366	Alpha amylase catalytic
EYQ98_RS04285	COG2182	Extracellular solute-binding protein
EYQ98_RS04290	COG1175	transmembrane transport
EYQ98_RS04295	COG3833	ABC-type maltose transport systems, permease component
EYQ98_RS04300	COG5521	maltodextrose utilization protein MalA
EYQ98_RS04305	COG1554	hydrolase, family 65, central catalytic
EYQ98_RS04310	COG0366	Alpha amylase catalytic
EYQ98_RS04315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYQ98_RS04320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYQ98_RS04325	COG1846	Transcriptional regulator
EYQ98_RS04340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYQ98_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
EYQ98_RS04375	COG0702	epimerase
EYQ98_RS04385	COG2132	Multicopper oxidase
EYQ98_RS04400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYQ98_RS04405	COG0714	Associated with various cellular activities
EYQ98_RS04410	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EYQ98_RS04415	COG1305	Transglutaminase-like
EYQ98_RS04420	COG0519	Catalyzes the synthesis of GMP from XMP
EYQ98_RS04420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYQ98_RS04430	COG2252	PERMEase
EYQ98_RS04445	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EYQ98_RS04455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYQ98_RS04460	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EYQ98_RS04465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EYQ98_RS04470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYQ98_RS04475	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYQ98_RS04480	COG0047	phosphoribosylformylglycinamidine synthase activity
EYQ98_RS04485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYQ98_RS04490	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYQ98_RS04495	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYQ98_RS04500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYQ98_RS04505	COG0138	bifunctional purine biosynthesis protein purh
EYQ98_RS04510	COG0151	Belongs to the GarS family
EYQ98_RS04520	COG2124	cytochrome p450
EYQ98_RS04540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYQ98_RS04545	COG1470	cell adhesion involved in biofilm formation
EYQ98_RS04550	COG4496	protein, YerC YecD
EYQ98_RS04555	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EYQ98_RS04560	COG0210	DNA helicase
EYQ98_RS04565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYQ98_RS04570	COG4851	CamS sex pheromone cAM373 precursor
EYQ98_RS04575	COG2188	Transcriptional regulator
EYQ98_RS04595	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EYQ98_RS04600	COG0626	cystathionine gamma-synthase activity
EYQ98_RS04605	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EYQ98_RS04610	COG3457	Alanine racemase
EYQ98_RS04615	COG0363	glucosamine-6-phosphate deaminase activity
EYQ98_RS04620	COG1285	pathogenesis
EYQ98_RS04625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ98_RS04630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYQ98_RS04635	COG0154	amidase activity
EYQ98_RS04640	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYQ98_RS04655	COG4124	Belongs to the glycosyl hydrolase 26 family
EYQ98_RS04660	COG1309	transcriptional regulator
EYQ98_RS04665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYQ98_RS04675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS04680	COG1957	nucleoside hydrolase
EYQ98_RS04685	COG1597	lipid kinase activity
EYQ98_RS04690	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYQ98_RS04700	COG1263	PTS System
EYQ98_RS04700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS04700	COG2190	(PTS) system
EYQ98_RS04705	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS04710	COG3711	transcriptional antiterminator
EYQ98_RS04715	COG0457	Tetratricopeptide repeat
EYQ98_RS04735	COG0217	transcriptional regulatory protein
EYQ98_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS04755	COG0840	transmembrane signaling receptor activity
EYQ98_RS04760	COG0471	metal ion transport
EYQ98_RS04765	COG0488	(ABC) transporter
EYQ98_RS04775	COG1469	GTP cyclohydrolase I activity
EYQ98_RS04790	COG0523	cobalamin synthesis protein
EYQ98_RS04795	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EYQ98_RS04800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYQ98_RS04805	COG0156	8-amino-7-oxononanoate synthase activity
EYQ98_RS04810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYQ98_RS04815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYQ98_RS04820	COG2124	cytochrome p450
EYQ98_RS04830	COG0789	Transcriptional regulator
EYQ98_RS04835	COG2814	Major facilitator Superfamily
EYQ98_RS04840	COG0488	(ABC) transporter
EYQ98_RS04845	COG0513	Belongs to the DEAD box helicase family
EYQ98_RS04850	COG2130	NADP-dependent
EYQ98_RS04865	COG0471	metal ion transport
EYQ98_RS04880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS04890	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EYQ98_RS04895	COG5658	integral membrane protein
EYQ98_RS04900	COG0640	Transcriptional regulator
EYQ98_RS04905	COG1254	Belongs to the acylphosphatase family
EYQ98_RS04910	COG2258	MOSC domain
EYQ98_RS04920	COG0024	Methionine aminopeptidase
EYQ98_RS04925	COG1368	sulfuric ester hydrolase activity
EYQ98_RS04940	COG1263	PTS System
EYQ98_RS04940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS04945	COG0366	Alpha amylase catalytic
EYQ98_RS04950	COG2188	Transcriptional regulator
EYQ98_RS04975	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYQ98_RS04980	COG1045	serine acetyltransferase
EYQ98_RS04985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYQ98_RS04995	COG1215	transferase activity, transferring glycosyl groups
EYQ98_RS05000	COG0463	Glycosyl transferase, family 2
EYQ98_RS05000	COG0457	Tetratricopeptide repeat
EYQ98_RS05010	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS05020	COG0657	acetylesterase activity
EYQ98_RS05025	COG1733	regulation of RNA biosynthetic process
EYQ98_RS05030	COG0778	Nitroreductase
EYQ98_RS05040	COG0693	protein deglycase activity
EYQ98_RS05045	COG4840	Belongs to the UPF0435 family
EYQ98_RS05050	COG1115	amino acid carrier protein
EYQ98_RS05055	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYQ98_RS05060	COG4980	gas vesicle protein
EYQ98_RS05065	COG1295	ribonuclease BN
EYQ98_RS05070	COG0477	Major facilitator Superfamily
EYQ98_RS05080	COG0387	Pfam Sodium calcium exchanger
EYQ98_RS05090	COG0535	radical SAM domain protein
EYQ98_RS05100	COG0726	polysaccharide deacetylase
EYQ98_RS05105	COG0371	Dehydrogenase
EYQ98_RS05115	COG0598	Magnesium transport protein CorA
EYQ98_RS05120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EYQ98_RS05125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYQ98_RS05130	COG4637	Psort location Cytoplasmic, score
EYQ98_RS05155	COG1819	glycosyl
EYQ98_RS05165	COG0477	Major facilitator Superfamily
EYQ98_RS05170	COG1263	PTS System
EYQ98_RS05170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS05175	COG3711	transcriptional antiterminator
EYQ98_RS05180	COG0288	reversible hydration of carbon dioxide
EYQ98_RS05190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYQ98_RS05195	COG5609	conserved protein (DUF2294)
EYQ98_RS05205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYQ98_RS05210	COG0022	dehydrogenase e1 component
EYQ98_RS05215	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ98_RS05220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ98_RS05235	COG1486	melibiose metabolic process
EYQ98_RS05240	COG1737	Transcriptional regulator
EYQ98_RS05245	COG1263	PTS System
EYQ98_RS05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS05260	COG1733	regulation of RNA biosynthetic process
EYQ98_RS05265	COG2259	Doxx family
EYQ98_RS05270	COG2514	catechol 2,3-dioxygenase activity
EYQ98_RS05285	COG1917	Cupin 2, conserved barrel domain protein
EYQ98_RS05285	COG2207	Transcriptional regulator
EYQ98_RS05290	COG1653	transport
EYQ98_RS05295	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS05300	COG1051	belongs to the nudix hydrolase family
EYQ98_RS05310	COG0392	lysyltransferase activity
EYQ98_RS05310	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYQ98_RS05315	COG0384	phenazine biosynthesis protein PhzF
EYQ98_RS05320	COG0778	Nitroreductase
EYQ98_RS05345	COG2137	regulation of response to DNA damage stimulus
EYQ98_RS05375	COG0463	Glycosyl transferase, family 2
EYQ98_RS05385	COG4485	Bacterial membrane protein, YfhO
EYQ98_RS05390	COG1988	membrane-bound metal-dependent
EYQ98_RS05395	COG1194	a g-specific adenine glycosylase
EYQ98_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS05420	COG3557	Belongs to the UPF0374 family
EYQ98_RS05425	COG1132	(ABC) transporter
EYQ98_RS05430	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS05435	COG4608	Belongs to the ABC transporter superfamily
EYQ98_RS05440	COG0747	negative chemotaxis
EYQ98_RS05445	COG0601	transmembrane transport
EYQ98_RS05450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ98_RS05455	COG4129	membrane
EYQ98_RS05460	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYQ98_RS05465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYQ98_RS05470	COG0735	belongs to the Fur family
EYQ98_RS05580	COG0457	Tetratricopeptide repeat
EYQ98_RS05625	COG5444	nuclease activity
EYQ98_RS05640	COG5444	nuclease activity
EYQ98_RS05645	COG0457	Tetratricopeptide repeat
EYQ98_RS05650	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYQ98_RS05660	COG0710	3-dehydroquinate dehydratase activity
EYQ98_RS05665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYQ98_RS05670	COG1116	anion transmembrane transporter activity
EYQ98_RS05675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYQ98_RS05685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ98_RS05695	COG1476	TRANSCRIPTIONal
EYQ98_RS05705	COG1131	(ABC) transporter
EYQ98_RS05725	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYQ98_RS05735	COG3382	B3 4 domain protein
EYQ98_RS05740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYQ98_RS05750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYQ98_RS05755	COG0789	Transcriptional regulator
EYQ98_RS05760	COG1664	Polymer-forming cytoskeletal
EYQ98_RS05770	COG2766	serine protein kinase
EYQ98_RS05775	COG2718	Belongs to the UPF0229 family
EYQ98_RS05780	COG1566	PFAM secretion protein HlyD family protein
EYQ98_RS05785	COG2814	Major facilitator Superfamily
EYQ98_RS05790	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS05805	COG1131	(ABC) transporter
EYQ98_RS05810	COG1131	(ABC) transporter
EYQ98_RS05815	COG1131	(ABC) transporter
EYQ98_RS05820	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYQ98_RS05825	COG1278	Cold shock
EYQ98_RS05830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYQ98_RS05835	COG2011	ABC-type metal ion transport system permease component
EYQ98_RS05840	COG1464	Belongs to the NlpA lipoprotein family
EYQ98_RS05845	COG1823	symporter activity
EYQ98_RS05870	COG5577	PFAM Coat F domain
EYQ98_RS05875	COG5002	protein histidine kinase activity
EYQ98_RS05880	COG4085	toxin activity
EYQ98_RS05880	COG1525	nuclease
EYQ98_RS05880	COG0737	Belongs to the 5'-nucleotidase family
EYQ98_RS05885	COG3764	Sortase (surface protein transpeptidase)
EYQ98_RS05890	COG0564	pseudouridine synthase activity
EYQ98_RS05900	COG0517	IMP dehydrogenase activity
EYQ98_RS05905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYQ98_RS05910	COG3153	acetyltransferase
EYQ98_RS05910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYQ98_RS05915	COG0488	(ABC) transporter
EYQ98_RS05925	COG2116	formate transmembrane transporter activity
EYQ98_RS05930	COG0679	Auxin Efflux Carrier
EYQ98_RS05935	COG0604	alcohol dehydrogenase
EYQ98_RS05940	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EYQ98_RS05945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EYQ98_RS05950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYQ98_RS05955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYQ98_RS05960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYQ98_RS05975	COG2203	Gaf domain
EYQ98_RS05975	COG4585	Histidine kinase
EYQ98_RS05980	COG2197	response regulator
EYQ98_RS05985	COG0431	NADPH-dependent FMN reductase
EYQ98_RS06000	COG1959	2 iron, 2 sulfur cluster binding
EYQ98_RS06005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYQ98_RS06005	COG1017	nitric oxide dioxygenase activity
EYQ98_RS06010	COG2719	SpoVR family
EYQ98_RS06015	COG0791	NLP P60 protein
EYQ98_RS06015	COG1388	LysM domain
EYQ98_RS06020	COG0583	DNA-binding transcription factor activity
EYQ98_RS06025	COG0372	Belongs to the citrate synthase family
EYQ98_RS06030	COG2133	pyrroloquinoline quinone binding
EYQ98_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS06040	COG0733	neurotransmitter:sodium symporter activity
EYQ98_RS06050	COG2207	Transcriptional regulator
EYQ98_RS06050	COG3708	Transcriptional regulator
EYQ98_RS06080	COG0662	Cupin 2, conserved barrel domain protein
EYQ98_RS06090	COG0204	Acyl-transferase
EYQ98_RS06095	COG3152	Membrane
EYQ98_RS06105	COG1309	transcriptional regulator
EYQ98_RS06110	COG1253	flavin adenine dinucleotide binding
EYQ98_RS06115	COG0789	Transcriptional regulator
EYQ98_RS06120	COG1253	flavin adenine dinucleotide binding
EYQ98_RS06140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYQ98_RS06145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYQ98_RS06150	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ98_RS06160	COG0668	transmembrane transport
EYQ98_RS06165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYQ98_RS06175	COG0726	polysaccharide deacetylase
EYQ98_RS06185	COG1757	Na H antiporter
EYQ98_RS06190	COG2017	converts alpha-aldose to the beta-anomer
EYQ98_RS06215	COG0589	response to stress
EYQ98_RS06220	COG1132	(ABC) transporter
EYQ98_RS06225	COG1132	(ABC) transporter
EYQ98_RS06230	COG0702	epimerase
EYQ98_RS06245	COG3842	ATPase activity
EYQ98_RS06250	COG2508	Transcriptional regulator
EYQ98_RS06260	COG0189	ligase activity
EYQ98_RS06265	COG0189	ligase activity
EYQ98_RS06270	COG4399	Belongs to the UPF0754 family
EYQ98_RS06275	COG3679	Belongs to the UPF0342 family
EYQ98_RS06285	COG0561	phosphatase activity
EYQ98_RS06290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYQ98_RS06295	COG0475	glutathione-regulated potassium exporter activity
EYQ98_RS06300	COG0490	domain, Protein
EYQ98_RS06310	COG1024	Enoyl-CoA hydratase
EYQ98_RS06315	COG0457	Tetratricopeptide repeat
EYQ98_RS06330	COG4152	abc transporter atp-binding protein
EYQ98_RS06335	COG1668	transmembrane transport
EYQ98_RS06340	COG0420	3'-5' exonuclease activity
EYQ98_RS06345	COG4717	serine-type aminopeptidase activity
EYQ98_RS06350	COG3481	metal-dependent phosphohydrolase, HD sub domain
EYQ98_RS06360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYQ98_RS06390	COG1846	Transcriptional regulator
EYQ98_RS06395	COG4980	gas vesicle protein
EYQ98_RS06410	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYQ98_RS06415	COG0537	adenosine 5'-monophosphoramidase activity
EYQ98_RS06425	COG1131	(ABC) transporter
EYQ98_RS06430	COG4473	ABC transporter
EYQ98_RS06440	COG1473	amidohydrolase
EYQ98_RS06445	COG3069	C4-dicarboxylate transmembrane transporter activity
EYQ98_RS06450	COG2329	Antibiotic biosynthesis monooxygenase
EYQ98_RS06455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYQ98_RS06460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EYQ98_RS06465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYQ98_RS06470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EYQ98_RS06475	COG1309	transcriptional regulator
EYQ98_RS06480	COG1511	domain protein
EYQ98_RS06485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYQ98_RS06500	COG1301	dicarboxylic acid transport
EYQ98_RS06510	COG1234	tRNA 3'-trailer cleavage
EYQ98_RS06515	COG0095	Lipoate-protein ligase
EYQ98_RS06520	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS06530	COG1396	sequence-specific DNA binding
EYQ98_RS06545	COG0501	Belongs to the peptidase M48B family
EYQ98_RS06555	COG0697	spore germination
EYQ98_RS06560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EYQ98_RS06565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS06570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS06575	COG0406	alpha-ribazole phosphatase activity
EYQ98_RS06580	COG0840	transmembrane signaling receptor activity
EYQ98_RS06585	COG0723	plastoquinol--plastocyanin reductase activity
EYQ98_RS06585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYQ98_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS06600	COG4903	ComK protein
EYQ98_RS06610	COG0398	Pfam SNARE associated Golgi protein
EYQ98_RS06615	COG0681	Belongs to the peptidase S26 family
EYQ98_RS06620	COG1404	Belongs to the peptidase S8 family
EYQ98_RS06630	COG2508	Transcriptional regulator
EYQ98_RS06640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYQ98_RS06645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ98_RS06650	COG3257	ureidoglycine aminohydrolase activity
EYQ98_RS06655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYQ98_RS06660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYQ98_RS06665	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYQ98_RS06670	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYQ98_RS06680	COG0549	Belongs to the carbamate kinase family
EYQ98_RS06685	COG2814	Major facilitator Superfamily
EYQ98_RS06695	COG0457	Tetratricopeptide repeat
EYQ98_RS06715	COG1609	Transcriptional regulator
EYQ98_RS06720	COG1653	transport
EYQ98_RS06725	COG1175	transmembrane transport
EYQ98_RS06730	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS06735	COG1486	melibiose metabolic process
EYQ98_RS06740	COG3180	Ammonia monooxygenase
EYQ98_RS06755	COG3546	catalase activity
EYQ98_RS06760	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS06765	COG2814	Major facilitator Superfamily
EYQ98_RS06765	COG0477	Major facilitator Superfamily
EYQ98_RS06775	COG5002	protein histidine kinase activity
EYQ98_RS06780	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS06785	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EYQ98_RS06790	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYQ98_RS06795	COG4149	molybdate abc transporter
EYQ98_RS06800	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EYQ98_RS06805	COG1074	ATP-dependent DNA helicase activity
EYQ98_RS06810	COG0420	3'-5' exonuclease activity
EYQ98_RS06815	COG0419	ATPase involved in DNA repair
EYQ98_RS06860	COG5337	Spore coat protein CotH
EYQ98_RS06870	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYQ98_RS06890	COG0367	asparagine synthase
EYQ98_RS06900	COG0347	Belongs to the P(II) protein family
EYQ98_RS06905	COG0534	Mate efflux family protein
EYQ98_RS06910	COG1917	Cupin 2, conserved barrel domain protein
EYQ98_RS06910	COG2207	Transcriptional regulator
EYQ98_RS06920	COG1609	Transcriptional regulator
EYQ98_RS06925	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS06950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYQ98_RS06960	COG0076	glutamate decarboxylase activity
EYQ98_RS06985	COG2153	protein acetylation
EYQ98_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS06995	COG2378	regulation of single-species biofilm formation
EYQ98_RS07005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYQ98_RS07005	COG0646	methionine synthase
EYQ98_RS07010	COG1666	GTP binding
EYQ98_RS07015	COG2996	Protein conserved in bacteria
EYQ98_RS07030	COG1307	EDD domain protein, DegV family
EYQ98_RS07035	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS07045	COG0516	GMP reductase activity
EYQ98_RS07055	COG0561	phosphatase activity
EYQ98_RS07060	COG1073	alpha beta
EYQ98_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
EYQ98_RS07075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYQ98_RS07080	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYQ98_RS07085	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYQ98_RS07090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYQ98_RS07095	COG0505	Belongs to the CarA family
EYQ98_RS07100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYQ98_RS07105	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYQ98_RS07110	COG1968	undecaprenyl-diphosphatase activity
EYQ98_RS07125	COG2267	carboxylic ester hydrolase activity
EYQ98_RS07135	COG1744	ABC transporter substrate-binding protein PnrA-like
EYQ98_RS07150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYQ98_RS07155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYQ98_RS07160	COG5504	Zn-dependent protease
EYQ98_RS07165	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS07180	COG0601	transmembrane transport
EYQ98_RS07185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ98_RS07195	COG0180	Tryptophanyl-tRNA synthetase
EYQ98_RS07205	COG4166	transmembrane transport
EYQ98_RS07210	COG0601	transmembrane transport
EYQ98_RS07215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ98_RS07220	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS07225	COG4608	Belongs to the ABC transporter superfamily
EYQ98_RS07230	COG0456	acetyltransferase
EYQ98_RS07235	COG1393	Belongs to the ArsC family
EYQ98_RS07240	COG0861	Integral membrane protein TerC family
EYQ98_RS07250	COG4862	establishment of competence for transformation
EYQ98_RS07270	COG4565	transcriptional regulatory protein
EYQ98_RS07275	COG3290	protein histidine kinase activity
EYQ98_RS07280	COG4469	Competence protein
EYQ98_RS07285	COG1164	Oligoendopeptidase f
EYQ98_RS07290	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EYQ98_RS07295	COG2346	COG2346, Truncated hemoglobins
EYQ98_RS07300	COG0741	lytic transglycosylase activity
EYQ98_RS07305	COG4116	CYTH
EYQ98_RS07315	COG2357	RelA SpoT domain protein
EYQ98_RS07320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYQ98_RS07325	COG0564	pseudouridine synthase activity
EYQ98_RS07330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EYQ98_RS07340	COG0569	domain protein
EYQ98_RS07340	COG0475	glutathione-regulated potassium exporter activity
EYQ98_RS07345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EYQ98_RS07350	COG0352	thiamine-phosphate diphosphorylase activity
EYQ98_RS07360	COG2104	thiamine diphosphate biosynthetic process
EYQ98_RS07365	COG2022	thiamine diphosphate biosynthetic process
EYQ98_RS07370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYQ98_RS07375	COG0351	phosphomethylpyrimidine kinase
EYQ98_RS07380	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYQ98_RS07435	COG0210	DNA helicase
EYQ98_RS07445	COG0586	Pfam SNARE associated Golgi protein
EYQ98_RS07450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYQ98_RS07455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYQ98_RS07460	COG2246	polysaccharide biosynthetic process
EYQ98_RS07465	COG2153	protein acetylation
EYQ98_RS07470	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EYQ98_RS07475	COG2382	esterase
EYQ98_RS07495	COG0626	cystathionine gamma-synthase activity
EYQ98_RS07500	COG0626	cystathionine gamma-synthase activity
EYQ98_RS07505	COG5505	Protein of unknown function (DUF819)
EYQ98_RS07525	COG3507	Belongs to the glycosyl hydrolase 43 family
EYQ98_RS07545	COG0110	maltose O-acetyltransferase activity
EYQ98_RS07555	COG0583	DNA-binding transcription factor activity
EYQ98_RS07560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYQ98_RS07565	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYQ98_RS07570	COG0583	DNA-binding transcription factor activity
EYQ98_RS07575	COG0697	spore germination
EYQ98_RS07580	COG0346	lactoylglutathione lyase activity
EYQ98_RS07590	COG1388	LysM domain
EYQ98_RS07590	COG3584	3D domain protein
EYQ98_RS07595	COG2814	Major facilitator Superfamily
EYQ98_RS07600	COG1309	transcriptional regulator
EYQ98_RS07625	COG4195	phage-related replication protein
EYQ98_RS07630	COG2856	Zn peptidase
EYQ98_RS07635	COG1396	sequence-specific DNA binding
EYQ98_RS07650	COG1522	sequence-specific DNA binding
EYQ98_RS07655	COG1484	DNA-dependent DNA replication
EYQ98_RS07670	COG1595	DNA-templated transcription, initiation
EYQ98_RS07675	COG5484	DNA packaging
EYQ98_RS07675	COG3728	DNA packaging
EYQ98_RS07680	COG1783	phage Terminase large subunit
EYQ98_RS07685	COG5518	Phage portal protein
EYQ98_RS07690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EYQ98_RS07695	COG4653	Phage capsid family
EYQ98_RS07745	COG5412	phage tail tape measure protein
EYQ98_RS07745	COG3953	SLT domain
EYQ98_RS07750	COG1652	LysM domain
EYQ98_RS07755	COG4193	domain, Protein
EYQ98_RS07765	COG3628	GPW Gp25 family protein
EYQ98_RS07770	COG3299	homolog of phage Mu protein gp47
EYQ98_RS07775	COG3778	Protein conserved in bacteria
EYQ98_RS07810	COG1802	Transcriptional regulator
EYQ98_RS07815	COG1063	alcohol dehydrogenase
EYQ98_RS07820	COG1312	Catalyzes the dehydration of D-mannonate
EYQ98_RS07825	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS07830	COG1063	alcohol dehydrogenase
EYQ98_RS07850	COG0306	phosphate transporter
EYQ98_RS07855	COG1392	Phosphate transport regulator
EYQ98_RS07860	COG0405	Gamma-glutamyltransferase
EYQ98_RS07865	COG5578	integral membrane protein
EYQ98_RS07875	COG4753	response regulator
EYQ98_RS07875	COG2207	Transcriptional regulator
EYQ98_RS07880	COG1653	transport
EYQ98_RS07885	COG1175	transmembrane transport
EYQ98_RS07890	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS07895	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYQ98_RS07900	COG2207	Transcriptional regulator
EYQ98_RS07905	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS07915	COG5578	integral membrane protein
EYQ98_RS07920	COG3401	FG-GAP repeat protein
EYQ98_RS07930	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS07935	COG3401	FG-GAP repeat protein
EYQ98_RS07940	COG0667	Aldo Keto reductase
EYQ98_RS07945	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS07950	COG1874	Beta-galactosidase
EYQ98_RS07960	COG1653	transport
EYQ98_RS07965	COG4209	transmembrane transport
EYQ98_RS07970	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS07975	COG0531	amino acid
EYQ98_RS07980	COG0346	lactoylglutathione lyase activity
EYQ98_RS07990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYQ98_RS07995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYQ98_RS08000	COG2362	D-Aminopeptidase
EYQ98_RS08005	COG0601	transmembrane transport
EYQ98_RS08010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ98_RS08015	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS08020	COG4166	transmembrane transport
EYQ98_RS08025	COG1619	proteins homologs of microcin C7 resistance protein MccF
EYQ98_RS08030	COG4948	Mandelate Racemase Muconate Lactonizing
EYQ98_RS08035	COG0791	NLP P60 protein
EYQ98_RS08040	COG4608	Belongs to the ABC transporter superfamily
EYQ98_RS08045	COG1834	amidinotransferase
EYQ98_RS08050	COG1607	acyl-coa hydrolase
EYQ98_RS08055	COG2323	membrane
EYQ98_RS08060	COG3866	Pectate lyase
EYQ98_RS08080	COG2318	DinB family
EYQ98_RS08090	COG2076	Multidrug Resistance protein
EYQ98_RS08095	COG0788	formyltetrahydrofolate deformylase activity
EYQ98_RS08100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYQ98_RS08105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYQ98_RS08110	COG1764	response to oxidative stress
EYQ98_RS08120	COG1846	Transcriptional regulator
EYQ98_RS08125	COG1764	response to oxidative stress
EYQ98_RS08135	COG0590	tRNA wobble adenosine to inosine editing
EYQ98_RS08140	COG0406	alpha-ribazole phosphatase activity
EYQ98_RS08155	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYQ98_RS08160	COG1404	Belongs to the peptidase S8 family
EYQ98_RS08170	COG2239	Acts as a magnesium transporter
EYQ98_RS08180	COG0789	Transcriptional regulator
EYQ98_RS08195	COG1846	Transcriptional regulator
EYQ98_RS08200	COG3285	dna ligase
EYQ98_RS08200	COG1793	dna ligase
EYQ98_RS08205	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EYQ98_RS08210	COG3300	MHYT domain
EYQ98_RS08210	COG5001	Diguanylate cyclase
EYQ98_RS08215	COG0586	Pfam SNARE associated Golgi protein
EYQ98_RS08225	COG1191	sigma factor activity
EYQ98_RS08245	COG0501	Belongs to the peptidase M48B family
EYQ98_RS08250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYQ98_RS08255	COG0768	penicillin binding
EYQ98_RS08270	COG3594	Acyltransferase
EYQ98_RS08275	COG5002	protein histidine kinase activity
EYQ98_RS08280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYQ98_RS08285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EYQ98_RS08290	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EYQ98_RS08295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYQ98_RS08300	COG0436	Aminotransferase
EYQ98_RS08305	COG1850	ribulose-bisphosphate carboxylase activity
EYQ98_RS08310	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EYQ98_RS08310	COG0235	Class ii aldolase
EYQ98_RS08315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EYQ98_RS08320	COG0346	lactoylglutathione lyase activity
EYQ98_RS08325	COG3339	Conserved Protein
EYQ98_RS08335	COG3852	Histidine kinase
EYQ98_RS08340	COG1846	Transcriptional regulator
EYQ98_RS08345	COG1360	Flagellar Motor Protein
EYQ98_RS08350	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYQ98_RS08355	COG0542	response to heat
EYQ98_RS08360	COG3949	Membrane
EYQ98_RS08365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYQ98_RS08370	COG0720	synthase
EYQ98_RS08375	COG0602	queuosine metabolic process
EYQ98_RS08380	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYQ98_RS08390	COG4974	Belongs to the 'phage' integrase family
EYQ98_RS08395	COG4974	Belongs to the 'phage' integrase family
EYQ98_RS08445	COG5444	nuclease activity
EYQ98_RS08535	COG0582	viral genome integration into host DNA
EYQ98_RS08665	COG3409	Peptidoglycan-binding domain 1 protein
EYQ98_RS08665	COG1388	LysM domain
EYQ98_RS08665	COG5632	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS08690	COG0582	viral genome integration into host DNA
EYQ98_RS08705	COG3739	integral membrane protein
EYQ98_RS08710	COG3655	Transcriptional regulator
EYQ98_RS08740	COG4873	Protein conserved in bacteria
EYQ98_RS08750	COG3773	Cell wall hydrolase
EYQ98_RS08755	COG2244	polysaccharide biosynthetic process
EYQ98_RS08760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS08765	COG2217	Heavy metal translocating P-type atpase
EYQ98_RS08770	COG0006	proline dipeptidase activity
EYQ98_RS08780	COG1609	Transcriptional regulator
EYQ98_RS08785	COG3711	transcriptional antiterminator
EYQ98_RS08790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS08790	COG2190	(PTS) system
EYQ98_RS08790	COG1263	PTS System
EYQ98_RS08795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS08800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYQ98_RS08810	COG1533	DNA photolyase activity
EYQ98_RS08815	COG0456	acetyltransferase
EYQ98_RS08820	COG0840	transmembrane signaling receptor activity
EYQ98_RS08825	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS08830	COG2084	Dehydrogenase
EYQ98_RS08835	COG2340	Cysteine-rich secretory protein family
EYQ98_RS08840	COG0768	penicillin binding
EYQ98_RS08845	COG4191	Histidine kinase
EYQ98_RS08850	COG0436	Aminotransferase
EYQ98_RS08855	COG1714	RDD family
EYQ98_RS08865	COG0835	chemotaxis
EYQ98_RS08865	COG0784	Response regulator, receiver
EYQ98_RS08875	COG2814	Major facilitator Superfamily
EYQ98_RS08880	COG1376	ErfK ybiS ycfS ynhG family protein
EYQ98_RS08890	COG1408	metallophosphoesterase
EYQ98_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS08900	COG2200	EAL domain
EYQ98_RS08910	COG4703	Protein of unknown function (DUF1797)
EYQ98_RS08915	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EYQ98_RS08925	COG0517	IMP dehydrogenase activity
EYQ98_RS08930	COG0583	DNA-binding transcription factor activity
EYQ98_RS08935	COG0716	FMN binding
EYQ98_RS08945	COG0716	FMN binding
EYQ98_RS08950	COG2171	N-acyltransferase activity
EYQ98_RS08955	COG1473	amidohydrolase
EYQ98_RS08965	COG0450	alkyl hydroperoxide reductase
EYQ98_RS08970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS08985	COG0746	molybdenum cofactor guanylyltransferase activity
EYQ98_RS08990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYQ98_RS08995	COG0303	'Molybdopterin
EYQ98_RS09000	COG1763	Mo-molybdopterin cofactor biosynthetic process
EYQ98_RS09005	COG0314	molybdopterin synthase activity
EYQ98_RS09010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EYQ98_RS09020	COG1132	(ABC) transporter
EYQ98_RS09025	COG1132	(ABC) transporter
EYQ98_RS09035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYQ98_RS09040	COG1136	(ABC) transporter
EYQ98_RS09045	COG0577	efflux transmembrane transporter activity
EYQ98_RS09050	COG1349	DNA-binding transcription factor activity
EYQ98_RS09055	COG1105	Belongs to the carbohydrate kinase PfkB family
EYQ98_RS09060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS09060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS09060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS09080	COG0488	(ABC) transporter
EYQ98_RS09090	COG2309	aminopeptidase activity
EYQ98_RS09100	COG1077	Cell shape determining protein MreB Mrl
EYQ98_RS09105	COG2002	toxin-antitoxin pair type II binding
EYQ98_RS09110	COG3852	Histidine kinase
EYQ98_RS09115	COG0569	domain protein
EYQ98_RS09120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYQ98_RS09125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYQ98_RS09130	COG5503	Protein of unknown function (DUF1447)
EYQ98_RS09135	COG0561	phosphatase activity
EYQ98_RS09140	COG0242	peptide deformylase activity
EYQ98_RS09150	COG0497	DNA recombination
EYQ98_RS09155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYQ98_RS09160	COG0022	dehydrogenase e1 component
EYQ98_RS09165	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ98_RS09170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ98_RS09175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS09185	COG1982	Orn Lys Arg decarboxylase major
EYQ98_RS09195	COG4476	Belongs to the UPF0223 family
EYQ98_RS09200	COG4493	Belongs to the UPF0637 family
EYQ98_RS09210	COG0483	inositol monophosphate 1-phosphatase activity
EYQ98_RS09230	COG1595	DNA-templated transcription, initiation
EYQ98_RS09245	COG1217	gtp-binding protein TYPA
EYQ98_RS09255	COG1846	Transcriptional regulator
EYQ98_RS09260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYQ98_RS09265	COG4896	Protein conserved in bacteria
EYQ98_RS09275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EYQ98_RS09280	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYQ98_RS09285	COG2066	Belongs to the glutaminase family
EYQ98_RS09290	COG4838	Belongs to the UPF0358 family
EYQ98_RS09295	COG0772	Belongs to the SEDS family
EYQ98_RS09300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EYQ98_RS09305	COG1612	heme a metabolic process
EYQ98_RS09310	COG0109	protoheme IX farnesyltransferase activity
EYQ98_RS09315	COG2010	Cytochrome c
EYQ98_RS09315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYQ98_RS09320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYQ98_RS09325	COG1845	cytochrome c oxidase, subunit III
EYQ98_RS09330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYQ98_RS09335	COG3336	cytochrome c oxidase
EYQ98_RS09345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EYQ98_RS09350	COG2340	Cysteine-rich secretory protein family
EYQ98_RS09365	COG3679	Belongs to the UPF0342 family
EYQ98_RS09370	COG4471	UPF0298 protein
EYQ98_RS09375	COG0742	ribosomal rna small subunit methyltransferase
EYQ98_RS09380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYQ98_RS09385	COG3314	Sporulation integral membrane protein YlbJ
EYQ98_RS09395	COG3480	Lon protease (S16) C-terminal proteolytic domain
EYQ98_RS09400	COG1323	Belongs to the UPF0348 family
EYQ98_RS09405	COG1399	metal-binding, possibly nucleic acid-binding protein
EYQ98_RS09410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYQ98_RS09420	COG0454	-acetyltransferase
EYQ98_RS09425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EYQ98_RS09430	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EYQ98_RS09435	COG2001	Belongs to the MraZ family
EYQ98_RS09440	COG0275	rRNA processing
EYQ98_RS09445	COG4839	cell division protein FtsL
EYQ98_RS09450	COG0768	penicillin binding
EYQ98_RS09455	COG0768	penicillin binding
EYQ98_RS09460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYQ98_RS09465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYQ98_RS09470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYQ98_RS09475	COG0772	Belongs to the SEDS family
EYQ98_RS09480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ98_RS09485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYQ98_RS09490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYQ98_RS09495	COG3879	Bacterial protein of unknown function (DUF881)
EYQ98_RS09500	COG3879	Bacterial protein of unknown function (DUF881)
EYQ98_RS09505	COG3856	small basic protein
EYQ98_RS09510	COG0849	cell division
EYQ98_RS09515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYQ98_RS09525	COG1404	Belongs to the peptidase S8 family
EYQ98_RS09525	COG4412	M6 family metalloprotease domain protein
EYQ98_RS09530	COG4412	M6 family metalloprotease domain protein
EYQ98_RS09530	COG1404	Belongs to the peptidase S8 family
EYQ98_RS09540	COG1191	sigma factor activity
EYQ98_RS09545	COG1191	sigma factor activity
EYQ98_RS09550	COG1119	ATPase activity
EYQ98_RS09555	COG0500	methyltransferase
EYQ98_RS09560	COG1873	PFAM PRC-barrel domain
EYQ98_RS09565	COG1496	oxidoreductase activity
EYQ98_RS09570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYQ98_RS09575	COG1799	cell septum assembly
EYQ98_RS09580	COG0762	integral membrane protein
EYQ98_RS09585	COG2302	S4 RNA-binding domain
EYQ98_RS09590	COG3599	regulation of cell shape
EYQ98_RS09595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYQ98_RS09600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYQ98_RS09605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYQ98_RS09610	COG0564	pseudouridine synthase activity
EYQ98_RS09615	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EYQ98_RS09620	COG2233	PERMEase
EYQ98_RS09625	COG0540	Belongs to the ATCase OTCase family
EYQ98_RS09630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYQ98_RS09635	COG0505	Belongs to the CarA family
EYQ98_RS09640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYQ98_RS09645	COG0543	2 iron, 2 sulfur cluster binding
EYQ98_RS09650	COG0167	dihydroorotate dehydrogenase activity
EYQ98_RS09655	COG0284	orotidine-5'-phosphate decarboxylase activity
EYQ98_RS09660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYQ98_RS09670	COG0175	sulfate reduction
EYQ98_RS09675	COG0306	phosphate transporter
EYQ98_RS09680	COG2046	Belongs to the sulfate adenylyltransferase family
EYQ98_RS09685	COG0529	Catalyzes the synthesis of activated sulfate
EYQ98_RS09690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYQ98_RS09695	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EYQ98_RS09710	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYQ98_RS09715	COG1561	YicC-like family, N-terminal region
EYQ98_RS09720	COG2052	Domain of unknown function (DUF370)
EYQ98_RS09725	COG0194	GDP metabolic process
EYQ98_RS09730	COG1758	RNA polymerase activity
EYQ98_RS09735	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYQ98_RS09740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYQ98_RS09745	COG0242	peptide deformylase activity
EYQ98_RS09750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYQ98_RS09755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYQ98_RS09755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYQ98_RS09760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYQ98_RS09765	COG0631	protein serine/threonine phosphatase activity
EYQ98_RS09770	COG2815	serine threonine protein kinase
EYQ98_RS09770	COG0515	serine threonine protein kinase
EYQ98_RS09775	COG1162	GTPase activity
EYQ98_RS09780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYQ98_RS09785	COG1564	THIamine pyrophosphokinase
EYQ98_RS09795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYQ98_RS09800	COG1302	Protein conserved in bacteria
EYQ98_RS09805	COG1461	Dihydroxyacetone kinase
EYQ98_RS09810	COG1760	l-serine dehydratase
EYQ98_RS09815	COG1760	l-serine dehydratase
EYQ98_RS09820	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYQ98_RS09825	COG1349	DNA-binding transcription factor activity
EYQ98_RS09830	COG0416	fatty acid biosynthetic process
EYQ98_RS09835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYQ98_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS09845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYQ98_RS09850	COG0571	ribonuclease III activity
EYQ98_RS09860	COG0552	protein localization to endoplasmic reticulum
EYQ98_RS09865	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EYQ98_RS09870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYQ98_RS09875	COG0228	four-way junction DNA binding
EYQ98_RS09880	COG1837	Belongs to the UPF0109 family
EYQ98_RS09890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYQ98_RS09895	COG0336	Belongs to the RNA methyltransferase TrmD family
EYQ98_RS09900	COG0335	large ribosomal subunit rRNA binding
EYQ98_RS09905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYQ98_RS09910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYQ98_RS09920	COG2257	FlhB HrpN YscU SpaS Family
EYQ98_RS09925	COG0045	succinate-CoA ligase (ADP-forming) activity
EYQ98_RS09930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYQ98_RS09935	COG0758	DNA mediated transformation
EYQ98_RS09940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYQ98_RS09945	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EYQ98_RS09950	COG4974	Belongs to the 'phage' integrase family
EYQ98_RS09955	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYQ98_RS09960	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EYQ98_RS09965	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EYQ98_RS09970	COG1815	bacterial-type flagellum-dependent cell motility
EYQ98_RS09975	COG1558	bacterial-type flagellum-dependent cell motility
EYQ98_RS09980	COG1677	Flagellar hook-basal body complex protein FliE
EYQ98_RS09985	COG1766	The M ring may be actively involved in energy transduction
EYQ98_RS09990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYQ98_RS09995	COG1317	bacterial-type flagellum organization
EYQ98_RS10000	COG1157	protein secretion by the type III secretion system
EYQ98_RS10005	COG2882	bacterial-type flagellum organization
EYQ98_RS10015	COG3144	bacterial-type flagellum assembly
EYQ98_RS10020	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYQ98_RS10025	COG4786	Flagellar basal body rod
EYQ98_RS10030	COG1582	Flagellar protein (FlbD)
EYQ98_RS10035	COG1580	Controls the rotational direction of flagella during chemotaxis
EYQ98_RS10040	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYQ98_RS10045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYQ98_RS10045	COG1776	CheC inhibitor of MCP methylation
EYQ98_RS10050	COG2201	protein-glutamate methylesterase activity
EYQ98_RS10055	COG3190	flagellar
EYQ98_RS10060	COG1338	Plays a role in the flagellum-specific transport system
EYQ98_RS10065	COG1987	bacterial-type flagellum assembly
EYQ98_RS10070	COG1684	flagellar biosynthetic protein fliR
EYQ98_RS10075	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYQ98_RS10080	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYQ98_RS10085	COG1419	protein localization to endoplasmic reticulum
EYQ98_RS10090	COG0455	bacterial-type flagellum organization
EYQ98_RS10095	COG2201	protein-glutamate methylesterase activity
EYQ98_RS10100	COG2198	Histidine kinase
EYQ98_RS10100	COG0643	Histidine kinase
EYQ98_RS10105	COG0835	chemotaxis
EYQ98_RS10110	COG1776	CheC inhibitor of MCP methylation
EYQ98_RS10115	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EYQ98_RS10120	COG1191	sigma factor activity
EYQ98_RS10130	COG0052	Belongs to the universal ribosomal protein uS2 family
EYQ98_RS10135	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYQ98_RS10140	COG0528	UMP kinase activity
EYQ98_RS10145	COG0233	cytoplasmic translational termination
EYQ98_RS10150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYQ98_RS10155	COG4589	Belongs to the CDS family
EYQ98_RS10160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYQ98_RS10165	COG0750	zinc metalloprotease
EYQ98_RS10170	COG0442	prolyl-tRNA aminoacylation
EYQ98_RS10175	COG2176	DNA-directed DNA polymerase activity
EYQ98_RS10205	COG0779	Required for maturation of 30S ribosomal subunits
EYQ98_RS10210	COG0195	Participates in both transcription termination and antitermination
EYQ98_RS10215	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EYQ98_RS10220	COG1358	cellular component organization or biogenesis
EYQ98_RS10225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYQ98_RS10230	COG1550	Protein conserved in bacteria
EYQ98_RS10235	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYQ98_RS10240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYQ98_RS10245	COG0196	riboflavin kinase activity
EYQ98_RS10250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYQ98_RS10255	COG1185	polyribonucleotide nucleotidyltransferase activity
EYQ98_RS10260	COG0726	polysaccharide deacetylase
EYQ98_RS10265	COG0612	Peptidase, M16
EYQ98_RS10270	COG1873	PFAM PRC-barrel domain
EYQ98_RS10275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ98_RS10280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYQ98_RS10285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYQ98_RS10290	COG0527	aspartate kinase activity
EYQ98_RS10300	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYQ98_RS10305	COG0740	serine-type endopeptidase activity
EYQ98_RS10315	COG1674	ftsk spoiiie
EYQ98_RS10315	COG4980	gas vesicle protein
EYQ98_RS10320	COG2188	Transcriptional regulator
EYQ98_RS10325	COG2814	Major facilitator Superfamily
EYQ98_RS10330	COG0612	Peptidase, M16
EYQ98_RS10335	COG0612	Peptidase, M16
EYQ98_RS10340	COG0300	oxidoreductase activity
EYQ98_RS10355	COG1426	Protein conserved in bacteria
EYQ98_RS10360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYQ98_RS10365	COG1546	Belongs to the CinA family
EYQ98_RS10365	COG1058	Belongs to the CinA family
EYQ98_RS10375	COG1418	mRNA catabolic process
EYQ98_RS10380	COG1692	metallophosphoesterase
EYQ98_RS10385	COG2359	stage V sporulation protein S
EYQ98_RS10395	COG1063	alcohol dehydrogenase
EYQ98_RS10400	COG0156	8-amino-7-oxononanoate synthase activity
EYQ98_RS10405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYQ98_RS10410	COG4550	Control of competence regulator ComK, YlbF/YmcA
EYQ98_RS10420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYQ98_RS10425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYQ98_RS10430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EYQ98_RS10435	COG5444	nuclease activity
EYQ98_RS10455	COG0523	cobalamin synthesis protein
EYQ98_RS10465	COG1247	-acetyltransferase
EYQ98_RS10480	COG1231	oxidoreductase activity
EYQ98_RS10485	COG3619	membrane
EYQ98_RS10490	COG3263	regulation of cellular component size
EYQ98_RS10495	COG2814	Major facilitator Superfamily
EYQ98_RS10510	COG0393	Putative heavy-metal-binding
EYQ98_RS10515	COG0398	Pfam SNARE associated Golgi protein
EYQ98_RS10520	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EYQ98_RS10525	COG1819	glycosyl
EYQ98_RS10530	COG0531	amino acid
EYQ98_RS10535	COG5577	PFAM Coat F domain
EYQ98_RS10545	COG3858	chitin binding
EYQ98_RS10545	COG1388	LysM domain
EYQ98_RS10550	COG1309	transcriptional regulator
EYQ98_RS10555	COG3631	Ketosteroid isomerase-related protein
EYQ98_RS10560	COG0702	epimerase
EYQ98_RS10570	COG1764	response to oxidative stress
EYQ98_RS10575	COG2076	Multidrug Resistance protein
EYQ98_RS10580	COG2076	Multidrug Resistance protein
EYQ98_RS10595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYQ98_RS10600	COG1923	regulation of RNA biosynthetic process
EYQ98_RS10615	COG1780	Probably involved in ribonucleotide reductase function
EYQ98_RS10620	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYQ98_RS10625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYQ98_RS10630	COG4112	unkown
EYQ98_RS10645	COG0735	belongs to the Fur family
EYQ98_RS10650	COG1802	Transcriptional regulator
EYQ98_RS10655	COG0697	spore germination
EYQ98_RS10690	COG1309	transcriptional regulator
EYQ98_RS10740	COG0464	growth
EYQ98_RS10745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYQ98_RS10750	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EYQ98_RS10755	COG0789	Transcriptional regulator
EYQ98_RS10760	COG0174	glutamine synthetase
EYQ98_RS10800	COG1073	alpha beta
EYQ98_RS10840	COG1309	transcriptional regulator
EYQ98_RS10845	COG2076	Multidrug Resistance protein
EYQ98_RS10850	COG2076	Multidrug Resistance protein
EYQ98_RS10855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS10900	COG1846	Transcriptional regulator
EYQ98_RS10905	COG0778	Nitroreductase
EYQ98_RS10910	COG0346	lactoylglutathione lyase activity
EYQ98_RS10915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYQ98_RS10920	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS10940	COG3209	COG3209 Rhs family protein
EYQ98_RS10945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYQ98_RS10950	COG1388	LysM domain
EYQ98_RS10955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYQ98_RS10960	COG4224	UPF0291 protein
EYQ98_RS10965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EYQ98_RS10975	COG3763	UPF0154 protein
EYQ98_RS10985	COG0785	Cytochrome C biogenesis protein
EYQ98_RS10990	COG2201	protein-glutamate methylesterase activity
EYQ98_RS10995	COG4846	Membrane protein involved in cytochrome C biogenesis
EYQ98_RS11005	COG0071	Belongs to the small heat shock protein (HSP20) family
EYQ98_RS11020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYQ98_RS11025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS11045	COG0824	Thioesterase
EYQ98_RS11070	COG4841	protein insertion into membrane
EYQ98_RS11075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYQ98_RS11080	COG1832	CoA-binding protein
EYQ98_RS11085	COG0187	DNA topoisomerase II activity
EYQ98_RS11090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYQ98_RS11095	COG1609	Transcriptional regulator
EYQ98_RS11110	COG2160	L-arabinose isomerase activity
EYQ98_RS11130	COG1115	amino acid carrier protein
EYQ98_RS11140	COG2181	nitrate reductase activity
EYQ98_RS11145	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EYQ98_RS11150	COG1140	nitrate reductase beta subunit
EYQ98_RS11155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EYQ98_RS11170	COG0535	radical SAM domain protein
EYQ98_RS11175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYQ98_RS11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYQ98_RS11190	COG2223	nitrite transmembrane transporter activity
EYQ98_RS11210	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EYQ98_RS11220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EYQ98_RS11230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS11240	COG0492	ferredoxin-NADP+ reductase activity
EYQ98_RS11255	COG3420	alginic acid biosynthetic process
EYQ98_RS11260	COG1114	Component of the transport system for branched-chain amino acids
EYQ98_RS11265	COG1064	alcohol dehydrogenase
EYQ98_RS11270	COG0789	Transcriptional regulator
EYQ98_RS11295	COG1024	Enoyl-CoA hydratase
EYQ98_RS11300	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS11305	COG2084	Dehydrogenase
EYQ98_RS11310	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS11315	COG1482	cell wall glycoprotein biosynthetic process
EYQ98_RS11320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS11320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS11320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS11345	COG3711	transcriptional antiterminator
EYQ98_RS11345	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS11360	COG1725	Transcriptional regulator
EYQ98_RS11365	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS11370	COG1312	Catalyzes the dehydration of D-mannonate
EYQ98_RS11385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EYQ98_RS11395	COG1609	Transcriptional regulator
EYQ98_RS11400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYQ98_RS11405	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EYQ98_RS11410	COG0640	Transcriptional regulator
EYQ98_RS11420	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EYQ98_RS11435	COG1649	PFAM Uncharacterised BCR, COG1649
EYQ98_RS11445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYQ98_RS11455	COG2027	D-alanyl-D-alanine carboxypeptidase
EYQ98_RS11460	COG1252	NADH dehydrogenase
EYQ98_RS11475	COG0166	Belongs to the GPI family
EYQ98_RS11485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYQ98_RS11490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYQ98_RS11495	COG1024	Enoyl-CoA hydratase
EYQ98_RS11500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYQ98_RS11505	COG0511	ligase activity, forming carbon-carbon bonds
EYQ98_RS11510	COG0439	Biotin carboxylase
EYQ98_RS11515	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS11520	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS11525	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS11530	COG1733	regulation of RNA biosynthetic process
EYQ98_RS11535	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYQ98_RS11540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYQ98_RS11550	COG2323	membrane
EYQ98_RS11560	COG0306	phosphate transporter
EYQ98_RS11565	COG0175	sulfate reduction
EYQ98_RS11570	COG1809	phosphosulfolactate synthase activity
EYQ98_RS11575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS11580	COG4948	Mandelate Racemase Muconate Lactonizing
EYQ98_RS11585	COG2814	Major facilitator Superfamily
EYQ98_RS11590	COG0463	Glycosyl transferase, family 2
EYQ98_RS11605	COG0493	'glutamate synthase
EYQ98_RS11610	COG0067	glutamate synthase
EYQ98_RS11610	COG0069	glutamate synthase activity
EYQ98_RS11610	COG0070	glutamate synthase
EYQ98_RS11615	COG0583	DNA-binding transcription factor activity
EYQ98_RS11635	COG1846	Transcriptional regulator
EYQ98_RS11645	COG1132	(ABC) transporter
EYQ98_RS11655	COG0300	oxidoreductase activity
EYQ98_RS11660	COG3848	Pyruvate phosphate dikinase
EYQ98_RS11660	COG0574	Belongs to the PEP-utilizing enzyme family
EYQ98_RS11670	COG0477	Major facilitator Superfamily
EYQ98_RS11675	COG0243	molybdopterin cofactor binding
EYQ98_RS11680	COG1846	Transcriptional regulator
EYQ98_RS11690	COG0531	amino acid
EYQ98_RS11700	COG0531	amino acid
EYQ98_RS11710	COG0697	spore germination
EYQ98_RS11715	COG0488	(ABC) transporter
EYQ98_RS11720	COG0840	transmembrane signaling receptor activity
EYQ98_RS11725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ98_RS11730	COG1404	Belongs to the peptidase S8 family
EYQ98_RS11740	COG1309	transcriptional regulator
EYQ98_RS11745	COG1846	Transcriptional regulator
EYQ98_RS11775	COG1309	transcriptional regulator
EYQ98_RS11780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS11785	COG3708	Transcriptional regulator
EYQ98_RS11795	COG2378	regulation of single-species biofilm formation
EYQ98_RS11805	COG0640	Transcriptional regulator
EYQ98_RS11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS11820	COG0531	amino acid
EYQ98_RS11825	COG0741	lytic transglycosylase activity
EYQ98_RS11830	COG1086	Polysaccharide biosynthesis protein
EYQ98_RS11850	COG2322	membrane
EYQ98_RS11870	COG1388	LysM domain
EYQ98_RS11870	COG3584	3D domain protein
EYQ98_RS11875	COG0514	ATP-dependent DNA helicase (RecQ)
EYQ98_RS11895	COG2315	Protein conserved in bacteria
EYQ98_RS11915	COG2427	Protein of unknown function (DUF1641)
EYQ98_RS11920	COG3383	formate dehydrogenase (NAD+) activity
EYQ98_RS11985	COG0402	S-adenosylhomocysteine deaminase activity
EYQ98_RS12000	COG2267	carboxylic ester hydrolase activity
EYQ98_RS12015	COG1280	lysine exporter protein (LysE YggA)
EYQ98_RS12020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYQ98_RS12030	COG3848	Pyruvate phosphate dikinase
EYQ98_RS12030	COG0574	Belongs to the PEP-utilizing enzyme family
EYQ98_RS12035	COG1309	transcriptional regulator
EYQ98_RS12050	COG2318	DinB family
EYQ98_RS12055	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYQ98_RS12060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYQ98_RS12075	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS12080	COG2814	Major facilitator Superfamily
EYQ98_RS12100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYQ98_RS12110	COG0733	neurotransmitter:sodium symporter activity
EYQ98_RS12120	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ98_RS12125	COG0567	Dehydrogenase, E1 component
EYQ98_RS12130	COG4548	von Willebrand factor, type A
EYQ98_RS12135	COG0714	Associated with various cellular activities
EYQ98_RS12140	COG2032	superoxide dismutase activity
EYQ98_RS12145	COG1388	LysM domain
EYQ98_RS12145	COG0791	NLP P60 protein
EYQ98_RS12155	COG0534	Mate efflux family protein
EYQ98_RS12160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYQ98_RS12165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYQ98_RS12175	COG2962	Rard protein
EYQ98_RS12185	COG4305	rare lipoprotein A
EYQ98_RS12195	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS12200	COG1733	regulation of RNA biosynthetic process
EYQ98_RS12205	COG0778	Nitroreductase
EYQ98_RS12210	COG0400	carboxylic ester hydrolase activity
EYQ98_RS12220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ98_RS12225	COG3409	Peptidoglycan-binding domain 1 protein
EYQ98_RS12225	COG0793	Belongs to the peptidase S41A family
EYQ98_RS12230	COG2226	methyltransferase
EYQ98_RS12240	COG1876	peptidase activity
EYQ98_RS12245	COG0813	purine-nucleoside phosphorylase activity
EYQ98_RS12250	COG0701	Predicted permease
EYQ98_RS12270	COG0671	phosphoesterase, PA-phosphatase related
EYQ98_RS12285	COG4479	Belongs to the UPF0346 family
EYQ98_RS12295	COG1509	lysine 2,3-aminomutase activity
EYQ98_RS12300	COG0456	acetyltransferase
EYQ98_RS12305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ98_RS12310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYQ98_RS12315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EYQ98_RS12320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYQ98_RS12335	COG0456	acetyltransferase
EYQ98_RS12340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYQ98_RS12345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYQ98_RS12350	COG1846	Transcriptional regulator
EYQ98_RS12360	COG3706	GGDEF domain
EYQ98_RS12365	COG0534	Mate efflux family protein
EYQ98_RS12380	COG4698	Protein conserved in bacteria
EYQ98_RS12385	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS12390	COG1999	signal sequence binding
EYQ98_RS12405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYQ98_RS12410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EYQ98_RS12415	COG1272	protein, Hemolysin III
EYQ98_RS12420	COG0204	Acyl-transferase
EYQ98_RS12425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYQ98_RS12430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYQ98_RS12440	COG2136	Putative SAM-dependent methyltransferase
EYQ98_RS12440	COG2521	methyltransferase
EYQ98_RS12455	COG1413	lyase activity
EYQ98_RS12460	COG1418	mRNA catabolic process
EYQ98_RS12465	COG0386	Belongs to the glutathione peroxidase family
EYQ98_RS12470	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EYQ98_RS12475	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYQ98_RS12480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ98_RS12490	COG1278	Cold shock
EYQ98_RS12510	COG0328	RNA-DNA hybrid ribonuclease activity
EYQ98_RS12515	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYQ98_RS12520	COG0328	RNA-DNA hybrid ribonuclease activity
EYQ98_RS12530	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ98_RS12550	COG1755	Isoprenylcysteine carboxyl methyltransferase
EYQ98_RS12555	COG3424	synthase
EYQ98_RS12565	COG2233	PERMEase
EYQ98_RS12570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYQ98_RS12575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EYQ98_RS12580	COG1199	ATP-dependent helicase activity
EYQ98_RS12590	COG0116	Belongs to the methyltransferase superfamily
EYQ98_RS12600	COG3599	regulation of cell shape
EYQ98_RS12605	COG4474	Belongs to the UPF0398 family
EYQ98_RS12615	COG3359	exonuclease
EYQ98_RS12620	COG1205	dead DEAH box helicase
EYQ98_RS12620	COG1111	helicase
EYQ98_RS12625	COG2190	(PTS) system
EYQ98_RS12630	COG0071	Belongs to the small heat shock protein (HSP20) family
EYQ98_RS12665	COG3331	DNA recombination
EYQ98_RS12670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYQ98_RS12670	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYQ98_RS12680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYQ98_RS12685	COG3935	DnaD domain protein
EYQ98_RS12690	COG0017	Asparaginyl-tRNA synthetase
EYQ98_RS12695	COG0436	Aminotransferase
EYQ98_RS12700	COG5353	protein conserved in bacteria
EYQ98_RS12715	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYQ98_RS12720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYQ98_RS12725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYQ98_RS12740	COG0617	tRNA 3'-terminal CCA addition
EYQ98_RS12745	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS12750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYQ98_RS12755	COG1803	Methylglyoxal synthase
EYQ98_RS12760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYQ98_RS12765	COG1694	Mazg nucleotide pyrophosphohydrolase
EYQ98_RS12770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS12780	COG4347	Protein of unknown function (DUF1405)
EYQ98_RS12785	COG2010	Cytochrome c
EYQ98_RS12785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYQ98_RS12790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYQ98_RS12795	COG0723	plastoquinol--plastocyanin reductase activity
EYQ98_RS12805	COG5582	Belongs to the UPF0302 family
EYQ98_RS12810	COG0457	Tetratricopeptide repeat
EYQ98_RS12815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYQ98_RS12820	COG0287	Prephenate dehydrogenase
EYQ98_RS12825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYQ98_RS12830	COG0159	tryptophan synthase activity
EYQ98_RS12835	COG0133	tryptophan synthase activity
EYQ98_RS12840	COG0135	phosphoribosylanthranilate isomerase activity
EYQ98_RS12845	COG0134	indole-3-glycerol-phosphate synthase activity
EYQ98_RS12850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYQ98_RS12855	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYQ98_RS12860	COG4401	Chorismate mutase type I
EYQ98_RS12865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYQ98_RS12870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYQ98_RS12875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYQ98_RS12880	COG0105	UTP biosynthetic process
EYQ98_RS12885	COG0142	geranyltranstransferase activity
EYQ98_RS12890	COG2226	methyltransferase
EYQ98_RS12895	COG0142	geranyltranstransferase activity
EYQ98_RS12910	COG0776	regulation of translation
EYQ98_RS12915	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYQ98_RS12935	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYQ98_RS12940	COG1160	GTP binding
EYQ98_RS12965	COG1304	FMN binding
EYQ98_RS12970	COG0539	negative regulation of cytoplasmic translation
EYQ98_RS12975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYQ98_RS12985	COG3773	Cell wall hydrolase
EYQ98_RS12985	COG3409	Peptidoglycan-binding domain 1 protein
EYQ98_RS12990	COG2339	peptidase activity
EYQ98_RS13000	COG0492	ferredoxin-NADP+ reductase activity
EYQ98_RS13005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYQ98_RS13010	COG4862	establishment of competence for transformation
EYQ98_RS13015	COG1408	metallophosphoesterase
EYQ98_RS13025	COG1388	LysM domain
EYQ98_RS13030	COG1266	CAAX protease self-immunity
EYQ98_RS13035	COG0514	ATP-dependent DNA helicase (RecQ)
EYQ98_RS13040	COG4955	Helix-turn-helix domain
EYQ98_RS13045	COG1141	Ferredoxin
EYQ98_RS13050	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EYQ98_RS13055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYQ98_RS13060	COG0739	heme binding
EYQ98_RS13070	COG1595	DNA-templated transcription, initiation
EYQ98_RS13075	COG1316	TRANSCRIPTIONal
EYQ98_RS13090	COG5002	protein histidine kinase activity
EYQ98_RS13100	COG5002	protein histidine kinase activity
EYQ98_RS13105	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS13115	COG1333	cytochrome c biogenesis protein
EYQ98_RS13120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS13125	COG1187	pseudouridine synthase activity
EYQ98_RS13130	COG0700	Nucleoside recognition
EYQ98_RS13135	COG2715	membrane protein required for spore maturation
EYQ98_RS13140	COG1686	Belongs to the peptidase S11 family
EYQ98_RS13150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYQ98_RS13155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYQ98_RS13165	COG1547	Domain of unknown function (DUF309)
EYQ98_RS13170	COG0456	acetyltransferase
EYQ98_RS13175	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYQ98_RS13180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYQ98_RS13180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYQ98_RS13185	COG0307	riboflavin synthase, alpha
EYQ98_RS13190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYQ98_RS13190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYQ98_RS13215	COG0457	Tetratricopeptide repeat
EYQ98_RS13220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYQ98_RS13225	COG4086	secreted protein
EYQ98_RS13230	COG4195	phage-related replication protein
EYQ98_RS13235	COG0019	diaminopimelate decarboxylase activity
EYQ98_RS13245	COG0697	spore germination
EYQ98_RS13260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYQ98_RS13295	COG1686	Belongs to the peptidase S11 family
EYQ98_RS13300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYQ98_RS13305	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EYQ98_RS13310	COG4974	Belongs to the 'phage' integrase family
EYQ98_RS13320	COG0735	belongs to the Fur family
EYQ98_RS13325	COG1300	Membrane
EYQ98_RS13330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS13350	COG2153	protein acetylation
EYQ98_RS13355	COG1379	DNA repair
EYQ98_RS13360	COG0494	nUDIX hydrolase
EYQ98_RS13370	COG1309	transcriptional regulator
EYQ98_RS13380	COG0667	Aldo Keto reductase
EYQ98_RS13390	COG1073	alpha beta
EYQ98_RS13400	COG4918	Iron-sulphur cluster biosynthesis
EYQ98_RS13410	COG0456	acetyltransferase
EYQ98_RS13410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EYQ98_RS13415	COG2329	Antibiotic biosynthesis monooxygenase
EYQ98_RS13425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EYQ98_RS13435	COG0747	negative chemotaxis
EYQ98_RS13440	COG0601	transmembrane transport
EYQ98_RS13450	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS13460	COG0534	Mate efflux family protein
EYQ98_RS13475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYQ98_RS13490	COG0346	lactoylglutathione lyase activity
EYQ98_RS13495	COG1072	(Pantothenic acid kinase))
EYQ98_RS13510	COG1131	(ABC) transporter
EYQ98_RS13530	COG4195	phage-related replication protein
EYQ98_RS13540	COG0300	oxidoreductase activity
EYQ98_RS13545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS13550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYQ98_RS13555	COG4187	Peptidase family M20/M25/M40
EYQ98_RS13560	COG1902	pentaerythritol trinitrate reductase activity
EYQ98_RS13565	COG0596	Alpha beta hydrolase
EYQ98_RS13570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYQ98_RS13575	COG1234	tRNA 3'-trailer cleavage
EYQ98_RS13580	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYQ98_RS13595	COG2358	TRAP transporter, solute receptor (TAXI family
EYQ98_RS13600	COG2188	Transcriptional regulator
EYQ98_RS13605	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS13610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS13615	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYQ98_RS13620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS13625	COG1785	Belongs to the alkaline phosphatase family
EYQ98_RS13630	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS13635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EYQ98_RS13640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYQ98_RS13650	COG0706	membrane insertase activity
EYQ98_RS13655	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYQ98_RS13660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYQ98_RS13665	COG4129	membrane
EYQ98_RS13670	COG1126	abc transporter atp-binding protein
EYQ98_RS13675	COG0765	amino acid transport
EYQ98_RS13680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYQ98_RS13690	COG1597	lipid kinase activity
EYQ98_RS13695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYQ98_RS13700	COG0022	dehydrogenase e1 component
EYQ98_RS13705	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYQ98_RS13710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYQ98_RS13715	COG3426	butyrate kinase activity
EYQ98_RS13725	COG0280	phosphate acetyltransferase
EYQ98_RS13730	COG3829	transcription factor binding
EYQ98_RS13730	COG3290	protein histidine kinase activity
EYQ98_RS13740	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ98_RS13745	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS13760	COG1045	serine acetyltransferase
EYQ98_RS13770	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS13775	COG0750	zinc metalloprotease
EYQ98_RS13780	COG0497	DNA recombination
EYQ98_RS13785	COG1438	arginine binding
EYQ98_RS13790	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EYQ98_RS13795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYQ98_RS13800	COG0142	geranyltranstransferase activity
EYQ98_RS13805	COG1722	exodeoxyribonuclease VII activity
EYQ98_RS13810	COG1570	exodeoxyribonuclease VII activity
EYQ98_RS13815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYQ98_RS13820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYQ98_RS13825	COG1302	Protein conserved in bacteria
EYQ98_RS13830	COG0439	Biotin carboxylase
EYQ98_RS13835	COG0511	ligase activity, forming carbon-carbon bonds
EYQ98_RS13875	COG3854	ATPases associated with a variety of cellular activities
EYQ98_RS13885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYQ98_RS13890	COG0006	proline dipeptidase activity
EYQ98_RS13895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYQ98_RS13905	COG3872	metal-dependent enzyme
EYQ98_RS13915	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYQ98_RS13920	COG1321	iron dependent repressor
EYQ98_RS13925	COG0095	Lipoate-protein ligase
EYQ98_RS13930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ98_RS13935	COG2113	Glycine betaine
EYQ98_RS13940	COG4176	ABC-type proline glycine betaine transport system permease component
EYQ98_RS13945	COG4175	Glycine betaine
EYQ98_RS13945	COG0517	IMP dehydrogenase activity
EYQ98_RS13950	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYQ98_RS13955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYQ98_RS13960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYQ98_RS13965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYQ98_RS13990	COG0681	Belongs to the peptidase S26 family
EYQ98_RS14015	COG4940	Competence protein ComGF
EYQ98_RS14025	COG4970	Tfp pilus assembly protein FimT
EYQ98_RS14030	COG4537	Required for transformation and DNA binding
EYQ98_RS14035	COG1459	type II secretion system
EYQ98_RS14040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYQ98_RS14045	COG1366	Belongs to the anti-sigma-factor antagonist family
EYQ98_RS14055	COG1393	Belongs to the ArsC family
EYQ98_RS14065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS14075	COG0011	TIGRFAM Protein of
EYQ98_RS14085	COG2866	Carboxypeptidase
EYQ98_RS14090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS14095	COG1368	sulfuric ester hydrolase activity
EYQ98_RS14100	COG1940	carbohydrate kinase activity
EYQ98_RS14105	COG4483	Protein conserved in bacteria
EYQ98_RS14110	COG0697	spore germination
EYQ98_RS14115	COG0705	Rhomboid family
EYQ98_RS14115	COG0457	Tetratricopeptide repeat
EYQ98_RS14120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYQ98_RS14125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYQ98_RS14130	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS14145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYQ98_RS14150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYQ98_RS14155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYQ98_RS14160	COG0581	inorganic phosphate transmembrane transporter activity
EYQ98_RS14165	COG0573	inorganic phosphate transmembrane transporter activity
EYQ98_RS14170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYQ98_RS14175	COG0768	penicillin binding
EYQ98_RS14180	COG0477	Major facilitator Superfamily
EYQ98_RS14190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYQ98_RS14195	COG2839	Protein conserved in bacteria
EYQ98_RS14200	COG5521	maltodextrose utilization protein MalA
EYQ98_RS14205	COG1388	LysM domain
EYQ98_RS14210	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYQ98_RS14215	COG4709	membrane
EYQ98_RS14220	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EYQ98_RS14225	COG0735	belongs to the Fur family
EYQ98_RS14230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYQ98_RS14235	COG1121	(ABC) transporter
EYQ98_RS14240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS14250	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EYQ98_RS14265	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYQ98_RS14270	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EYQ98_RS14275	COG2384	SAM-dependent methyltransferase
EYQ98_RS14325	COG5444	nuclease activity
EYQ98_RS14340	COG2010	Cytochrome c
EYQ98_RS14345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYQ98_RS14350	COG0358	DNA primase activity
EYQ98_RS14355	COG1671	Belongs to the UPF0178 family
EYQ98_RS14360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYQ98_RS14365	COG0517	IMP dehydrogenase activity
EYQ98_RS14370	COG0751	glycine-tRNA ligase activity
EYQ98_RS14375	COG0752	glycyl-tRNA synthetase alpha subunit
EYQ98_RS14380	COG1381	Involved in DNA repair and RecF pathway recombination
EYQ98_RS14390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYQ98_RS14395	COG0295	cytidine deaminase activity
EYQ98_RS14400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYQ98_RS14405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYQ98_RS14410	COG1480	7TM receptor with intracellular HD hydrolase
EYQ98_RS14415	COG1702	phosphate starvation-inducible protein PhoH
EYQ98_RS14420	COG0561	phosphatase activity
EYQ98_RS14435	COG4864	UPF0365 protein
EYQ98_RS14440	COG1030	water channel activity
EYQ98_RS14445	COG1610	YqeY-like protein
EYQ98_RS14450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYQ98_RS14455	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYQ98_RS14460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYQ98_RS14465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYQ98_RS14470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYQ98_RS14475	COG2264	protein methyltransferase activity
EYQ98_RS14480	COG0484	heat shock protein binding
EYQ98_RS14485	COG0443	Heat shock 70 kDa protein
EYQ98_RS14490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYQ98_RS14495	COG1420	regulation of RNA biosynthetic process
EYQ98_RS14500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYQ98_RS14505	COG0481	GTPase activity
EYQ98_RS14515	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS14520	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EYQ98_RS14525	COG0268	Binds directly to 16S ribosomal RNA
EYQ98_RS14530	COG1466	dna polymerase III delta subunit
EYQ98_RS14540	COG0658	competence protein
EYQ98_RS14540	COG2333	competence protein COMEC
EYQ98_RS14545	COG2131	deaminase
EYQ98_RS14550	COG1596	polysaccharide export
EYQ98_RS14550	COG1555	photosystem II stabilization
EYQ98_RS14555	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYQ98_RS14565	COG0799	negative regulation of ribosome biogenesis
EYQ98_RS14570	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYQ98_RS14575	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYQ98_RS14580	COG1534	Rna-binding protein
EYQ98_RS14585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYQ98_RS14590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EYQ98_RS14595	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EYQ98_RS14605	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS14610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS14615	COG5609	conserved protein (DUF2294)
EYQ98_RS14620	COG3383	formate dehydrogenase (NAD+) activity
EYQ98_RS14625	COG2427	Protein of unknown function (DUF1641)
EYQ98_RS14655	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS14710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ98_RS14710	COG0425	Belongs to the sulfur carrier protein TusA family
EYQ98_RS14720	COG2197	response regulator
EYQ98_RS14730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS14735	COG0730	response to heat
EYQ98_RS14740	COG0425	Belongs to the sulfur carrier protein TusA family
EYQ98_RS14745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ98_RS14745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS14750	COG0425	Belongs to the sulfur carrier protein TusA family
EYQ98_RS14750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ98_RS14755	COG2210	Belongs to the sulfur carrier protein TusA family
EYQ98_RS14760	COG1937	Protein conserved in bacteria
EYQ98_RS14805	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYQ98_RS14810	COG0113	porphobilinogen synthase activity
EYQ98_RS14815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EYQ98_RS14820	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EYQ98_RS14825	COG1733	regulation of RNA biosynthetic process
EYQ98_RS14830	COG3239	Fatty acid desaturase
EYQ98_RS14835	COG4585	Histidine kinase
EYQ98_RS14840	COG2197	response regulator
EYQ98_RS14845	COG0492	ferredoxin-NADP+ reductase activity
EYQ98_RS14850	COG0747	negative chemotaxis
EYQ98_RS14855	COG0601	transmembrane transport
EYQ98_RS14860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYQ98_RS14865	COG0444	Belongs to the ABC transporter superfamily
EYQ98_RS14870	COG4608	Belongs to the ABC transporter superfamily
EYQ98_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS14905	COG2124	cytochrome p450
EYQ98_RS14910	COG0730	response to heat
EYQ98_RS14925	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS14930	COG1621	beta-fructofuranosidase activity
EYQ98_RS14935	COG3716	PTS system mannose fructose sorbose family IID component
EYQ98_RS14940	COG3715	PTS system
EYQ98_RS14945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS14950	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS14975	COG2169	Transcriptional regulator
EYQ98_RS14980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYQ98_RS14985	COG0656	L-ascorbic acid biosynthetic process
EYQ98_RS14995	COG1733	regulation of RNA biosynthetic process
EYQ98_RS15000	COG3340	Belongs to the peptidase S51 family
EYQ98_RS15005	COG1587	Uroporphyrinogen-III synthase
EYQ98_RS15015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS15020	COG0583	DNA-binding transcription factor activity
EYQ98_RS15025	COG2814	Major facilitator Superfamily
EYQ98_RS15035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYQ98_RS15035	COG2124	cytochrome p450
EYQ98_RS15040	COG1309	transcriptional regulator
EYQ98_RS15045	COG1404	Belongs to the peptidase S8 family
EYQ98_RS15050	COG2226	methyltransferase
EYQ98_RS15075	COG0626	cystathionine gamma-synthase activity
EYQ98_RS15080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYQ98_RS15085	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYQ98_RS15090	COG2226	methyltransferase
EYQ98_RS15105	COG0768	penicillin binding
EYQ98_RS15110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYQ98_RS15115	COG0572	uridine kinase
EYQ98_RS15120	COG0826	peptidase U32
EYQ98_RS15125	COG0826	peptidase U32
EYQ98_RS15130	COG4122	O-methyltransferase activity
EYQ98_RS15135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYQ98_RS15140	COG3906	Belongs to the UPF0473 family
EYQ98_RS15145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYQ98_RS15150	COG4472	Bacterial protein of unknown function (DUF965)
EYQ98_RS15155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYQ98_RS15160	COG0628	permease
EYQ98_RS15175	COG3881	PFAM PRC-barrel domain
EYQ98_RS15185	COG0457	Tetratricopeptide repeat
EYQ98_RS15190	COG0482	sulfurtransferase activity
EYQ98_RS15195	COG1104	cysteine desulfurase activity
EYQ98_RS15200	COG1959	2 iron, 2 sulfur cluster binding
EYQ98_RS15205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYQ98_RS15210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYQ98_RS15220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYQ98_RS15225	COG0124	histidyl-tRNA synthetase
EYQ98_RS15230	COG3103	Sh3 type 3 domain protein
EYQ98_RS15230	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS15230	COG4991	sh3 domain protein
EYQ98_RS15235	COG1490	D-aminoacyl-tRNA deacylase activity
EYQ98_RS15240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYQ98_RS15245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYQ98_RS15250	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EYQ98_RS15250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYQ98_RS15255	COG5416	Lipopolysaccharide assembly protein A domain
EYQ98_RS15260	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYQ98_RS15260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYQ98_RS15270	COG2244	polysaccharide biosynthetic process
EYQ98_RS15275	COG2323	membrane
EYQ98_RS15285	COG1862	Preprotein translocase
EYQ98_RS15295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYQ98_RS15305	COG2255	four-way junction helicase activity
EYQ98_RS15310	COG0632	four-way junction helicase activity
EYQ98_RS15320	COG2112	serine threonine protein kinase
EYQ98_RS15330	COG2318	DinB family
EYQ98_RS15335	COG4195	phage-related replication protein
EYQ98_RS15350	COG0217	transcriptional regulatory protein
EYQ98_RS15360	COG1388	LysM domain
EYQ98_RS15365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYQ98_RS15370	COG0157	Belongs to the NadC ModD family
EYQ98_RS15375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EYQ98_RS15380	COG1104	cysteine desulfurase activity
EYQ98_RS15385	COG1827	regulation of RNA biosynthetic process
EYQ98_RS15390	COG0077	Prephenate dehydratase
EYQ98_RS15395	COG4492	Belongs to the UPF0735 family
EYQ98_RS15400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYQ98_RS15405	COG3290	protein histidine kinase activity
EYQ98_RS15410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYQ98_RS15415	COG2868	ribosomal protein
EYQ98_RS15420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYQ98_RS15425	COG1994	Peptidase M50
EYQ98_RS15430	COG0739	heme binding
EYQ98_RS15435	COG3832	glyoxalase III activity
EYQ98_RS15440	COG0640	Transcriptional regulator
EYQ98_RS15445	COG2894	cell division
EYQ98_RS15450	COG0850	regulation of cytokinetic process
EYQ98_RS15455	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EYQ98_RS15465	COG1077	Cell shape determining protein MreB Mrl
EYQ98_RS15510	COG5444	nuclease activity
EYQ98_RS15550	COG5434	Belongs to the glycosyl hydrolase 28 family
EYQ98_RS15555	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYQ98_RS15565	COG5280	Phage tail tape measure protein TP901
EYQ98_RS15565	COG3953	SLT domain
EYQ98_RS15625	COG4626	Terminase
EYQ98_RS15625	COG1802	Transcriptional regulator
EYQ98_RS15725	COG1396	sequence-specific DNA binding
EYQ98_RS15740	COG2003	Belongs to the UPF0758 family
EYQ98_RS15745	COG0424	maF-like protein
EYQ98_RS15760	COG0285	dihydrofolate synthase activity
EYQ98_RS15765	COG0525	valine-tRNA ligase activity
EYQ98_RS15775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYQ98_RS15780	COG1388	LysM domain
EYQ98_RS15785	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYQ98_RS15790	COG0113	porphobilinogen synthase activity
EYQ98_RS15795	COG1587	Uroporphyrinogen-III synthase
EYQ98_RS15800	COG0181	hydroxymethylbilane synthase activity
EYQ98_RS15805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYQ98_RS15820	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYQ98_RS15825	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYQ98_RS15830	COG0470	DNA polymerase III
EYQ98_RS15830	COG1067	ATP-dependent peptidase activity
EYQ98_RS15835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYQ98_RS15840	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYQ98_RS15845	COG0457	Tetratricopeptide repeat
EYQ98_RS15845	COG1477	protein flavinylation
EYQ98_RS15850	COG0066	3-isopropylmalate dehydratase activity
EYQ98_RS15855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYQ98_RS15860	COG0473	3-isopropylmalate dehydrogenase activity
EYQ98_RS15870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYQ98_RS15875	COG0440	acetolactate synthase activity
EYQ98_RS15880	COG0028	Belongs to the TPP enzyme family
EYQ98_RS15885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYQ98_RS15895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYQ98_RS15915	COG5518	Phage portal protein
EYQ98_RS15920	COG1783	phage Terminase large subunit
EYQ98_RS15960	COG5444	nuclease activity
EYQ98_RS15965	COG0457	Tetratricopeptide repeat
EYQ98_RS15985	COG0622	Phosphoesterase
EYQ98_RS15990	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYQ98_RS15995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYQ98_RS16000	COG5401	PFAM Sporulation and spore germination
EYQ98_RS16005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EYQ98_RS16010	COG1846	Transcriptional regulator
EYQ98_RS16015	COG2197	response regulator
EYQ98_RS16020	COG4221	oxidoreductase activity
EYQ98_RS16025	COG0824	Thioesterase
EYQ98_RS16030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EYQ98_RS16035	COG1053	succinate dehydrogenase
EYQ98_RS16040	COG2009	succinate dehydrogenase
EYQ98_RS16045	COG1719	4-vinyl reductase, 4VR
EYQ98_RS16050	COG0527	aspartate kinase activity
EYQ98_RS16060	COG0322	excinuclease ABC activity
EYQ98_RS16065	COG3118	belongs to the thioredoxin family
EYQ98_RS16070	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EYQ98_RS16075	COG2086	electron transfer activity
EYQ98_RS16080	COG1024	Enoyl-CoA hydratase
EYQ98_RS16085	COG1309	transcriptional regulator
EYQ98_RS16090	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS16095	COG3766	membrane
EYQ98_RS16100	COG1193	negative regulation of DNA recombination
EYQ98_RS16105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYQ98_RS16105	COG1796	DNA polymerase
EYQ98_RS16110	COG1286	toxin biosynthetic process
EYQ98_RS16115	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EYQ98_RS16120	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYQ98_RS16145	COG1137	ATPase activity
EYQ98_RS16160	COG0072	phenylalanine-tRNA ligase activity
EYQ98_RS16160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ98_RS16165	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYQ98_RS16170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYQ98_RS16180	COG1966	Carbon starvation protein
EYQ98_RS16195	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS16200	COG1175	transmembrane transport
EYQ98_RS16205	COG1653	transport
EYQ98_RS16210	COG0371	Dehydrogenase
EYQ98_RS16215	COG0235	Class ii aldolase
EYQ98_RS16220	COG1069	ribulokinase activity
EYQ98_RS16230	COG3507	Belongs to the glycosyl hydrolase 43 family
EYQ98_RS16235	COG1363	Peptidase, m42
EYQ98_RS16245	COG3326	Membrane
EYQ98_RS16250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYQ98_RS16255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYQ98_RS16260	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYQ98_RS16265	COG1346	cytolysis
EYQ98_RS16275	COG3540	Alkaline phosphatase
EYQ98_RS16280	COG3279	Response regulator of the LytR AlgR family
EYQ98_RS16285	COG3275	phosphorelay sensor kinase activity
EYQ98_RS16295	COG1011	Hydrolase
EYQ98_RS16300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYQ98_RS16310	COG0398	Pfam SNARE associated Golgi protein
EYQ98_RS16315	COG1484	DNA-dependent DNA replication
EYQ98_RS16320	COG3611	Membrane attachment protein
EYQ98_RS16325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYQ98_RS16340	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EYQ98_RS16345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYQ98_RS16350	COG3866	Pectate lyase
EYQ98_RS16360	COG1971	Probably functions as a manganese efflux pump
EYQ98_RS16365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYQ98_RS16370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ98_RS16370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYQ98_RS16375	COG5002	protein histidine kinase activity
EYQ98_RS16380	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS16385	COG0039	L-malate dehydrogenase activity
EYQ98_RS16390	COG0538	isocitrate dehydrogenase activity
EYQ98_RS16395	COG0372	Belongs to the citrate synthase family
EYQ98_RS16400	COG2707	UPF0756 membrane protein
EYQ98_RS16405	COG0628	permease
EYQ98_RS16410	COG3030	protein affecting phage T7 exclusion by the F plasmid
EYQ98_RS16420	COG0205	6-phosphofructokinase activity
EYQ98_RS16425	COG0825	malonyl-CoA metabolic process
EYQ98_RS16430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYQ98_RS16435	COG0281	malic enzyme
EYQ98_RS16440	COG0587	DNA-directed DNA polymerase activity
EYQ98_RS16460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EYQ98_RS16470	COG4109	DRTGG domain
EYQ98_RS16475	COG1695	Transcriptional regulator
EYQ98_RS16480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYQ98_RS16485	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS16490	COG0165	Argininosuccinate lyase
EYQ98_RS16495	COG0137	argininosuccinate synthase activity
EYQ98_RS16500	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYQ98_RS16505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EYQ98_RS16510	COG0827	DNA restriction-modification system
EYQ98_RS16515	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EYQ98_RS16520	COG3874	Sporulation protein YtfJ
EYQ98_RS16530	COG1714	RDD family
EYQ98_RS16535	COG0616	signal peptide processing
EYQ98_RS16540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYQ98_RS16545	COG1566	PFAM secretion protein HlyD family protein
EYQ98_RS16550	COG0477	Major facilitator Superfamily
EYQ98_RS16560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYQ98_RS16570	COG0301	tRNA thio-modification
EYQ98_RS16575	COG1104	cysteine desulfurase activity
EYQ98_RS16580	COG1114	Component of the transport system for branched-chain amino acids
EYQ98_RS16585	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EYQ98_RS16590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYQ98_RS16595	COG1309	transcriptional regulator
EYQ98_RS16600	COG1956	GAF domain-containing protein
EYQ98_RS16605	COG2203	Gaf domain
EYQ98_RS16605	COG2199	diguanylate cyclase activity
EYQ98_RS16610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYQ98_RS16625	COG3152	Membrane
EYQ98_RS16630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYQ98_RS16635	COG1522	sequence-specific DNA binding
EYQ98_RS16640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYQ98_RS16645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYQ98_RS16650	COG0454	-acetyltransferase
EYQ98_RS16655	COG0517	IMP dehydrogenase activity
EYQ98_RS16660	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYQ98_RS16665	COG1360	Flagellar Motor Protein
EYQ98_RS16670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYQ98_RS16675	COG1609	Transcriptional regulator
EYQ98_RS16680	COG1605	Chorismate mutase
EYQ98_RS16680	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EYQ98_RS16690	COG3118	belongs to the thioredoxin family
EYQ98_RS16695	COG4980	gas vesicle protein
EYQ98_RS16700	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EYQ98_RS16705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYQ98_RS16710	COG1674	ftsk spoiiie
EYQ98_RS16715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYQ98_RS16720	COG4848	Belongs to the UPF0354 family
EYQ98_RS16725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS16735	COG1363	Peptidase, m42
EYQ98_RS16740	COG5584	Small secreted protein
EYQ98_RS16745	COG0281	malic enzyme
EYQ98_RS16750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYQ98_RS16755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYQ98_RS16765	COG0510	thiamine kinase activity
EYQ98_RS16770	COG1523	belongs to the glycosyl hydrolase 13 family
EYQ98_RS16775	COG1597	lipid kinase activity
EYQ98_RS16785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EYQ98_RS16790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYQ98_RS16805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ98_RS16810	COG2252	PERMEase
EYQ98_RS16815	COG1349	DNA-binding transcription factor activity
EYQ98_RS16820	COG1187	pseudouridine synthase activity
EYQ98_RS16825	COG2244	polysaccharide biosynthetic process
EYQ98_RS16830	COG2081	HI0933 family
EYQ98_RS16835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EYQ98_RS16845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYQ98_RS16860	COG5578	integral membrane protein
EYQ98_RS16865	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS16870	COG1653	transport
EYQ98_RS16875	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYQ98_RS16880	COG4209	transmembrane transport
EYQ98_RS16885	COG2207	Transcriptional regulator
EYQ98_RS16890	COG1653	transport
EYQ98_RS16895	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS16900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYQ98_RS16905	COG1073	alpha beta
EYQ98_RS16915	COG0583	DNA-binding transcription factor activity
EYQ98_RS16920	COG0346	lactoylglutathione lyase activity
EYQ98_RS16925	COG0495	leucyl-tRNA aminoacylation
EYQ98_RS16935	COG2814	Major facilitator Superfamily
EYQ98_RS16945	COG2433	Pfam Transposase IS66
EYQ98_RS16950	COG0577	efflux transmembrane transporter activity
EYQ98_RS16955	COG1136	(ABC) transporter
EYQ98_RS16965	COG1131	(ABC) transporter
EYQ98_RS16970	COG1725	Transcriptional regulator
EYQ98_RS16980	COG1242	4 iron, 4 sulfur cluster binding
EYQ98_RS16985	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EYQ98_RS16990	COG1301	dicarboxylic acid transport
EYQ98_RS17000	COG2267	carboxylic ester hydrolase activity
EYQ98_RS17005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EYQ98_RS17010	COG0671	phosphoesterase, PA-phosphatase related
EYQ98_RS17015	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS17015	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ98_RS17025	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYQ98_RS17030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EYQ98_RS17035	COG1301	dicarboxylic acid transport
EYQ98_RS17045	COG1506	peptidase
EYQ98_RS17050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYQ98_RS17055	COG1116	anion transmembrane transporter activity
EYQ98_RS17060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYQ98_RS17065	COG0494	nUDIX hydrolase
EYQ98_RS17075	COG4824	toxin secretion phage lysis holin
EYQ98_RS17080	COG0783	Belongs to the Dps family
EYQ98_RS17095	COG1854	S-ribosylhomocysteine lyase activity
EYQ98_RS17100	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYQ98_RS17105	COG0288	reversible hydration of carbon dioxide
EYQ98_RS17110	COG0523	cobalamin synthesis protein
EYQ98_RS17115	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYQ98_RS17120	COG0254	rRNA binding
EYQ98_RS17125	COG1271	oxidase subunit
EYQ98_RS17130	COG1294	oxidase, subunit
EYQ98_RS17145	COG4948	Mandelate Racemase Muconate Lactonizing
EYQ98_RS17150	COG0318	PFAM AMP-dependent synthetase and ligase
EYQ98_RS17155	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EYQ98_RS17160	COG0596	Alpha beta hydrolase
EYQ98_RS17165	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EYQ98_RS17170	COG1169	isochorismate synthase
EYQ98_RS17175	COG1575	Belongs to the MenA family. Type 1 subfamily
EYQ98_RS17180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYQ98_RS17185	COG0058	SHG alpha-glucan phosphorylase activity
EYQ98_RS17190	COG0297	glycogen (starch) synthase activity
EYQ98_RS17195	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYQ98_RS17200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYQ98_RS17205	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYQ98_RS17330	COG1609	Transcriptional regulator
EYQ98_RS17335	COG3859	Proton-coupled thiamine transporter YuaJ
EYQ98_RS17340	COG3764	Sortase (surface protein transpeptidase)
EYQ98_RS17355	COG0457	Tetratricopeptide repeat
EYQ98_RS17365	COG0569	domain protein
EYQ98_RS17370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYQ98_RS17380	COG2318	DinB family
EYQ98_RS17390	COG1454	alcohol dehydrogenase
EYQ98_RS17395	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS17400	COG1510	regulation of RNA biosynthetic process
EYQ98_RS17410	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EYQ98_RS17415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYQ98_RS17420	COG2140	Oxalate decarboxylase
EYQ98_RS17465	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EYQ98_RS17475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYQ98_RS17480	COG0726	polysaccharide deacetylase
EYQ98_RS17485	COG1408	metallophosphoesterase
EYQ98_RS17490	COG1968	undecaprenyl-diphosphatase activity
EYQ98_RS17495	COG0628	permease
EYQ98_RS17500	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS17505	COG0693	protein deglycase activity
EYQ98_RS17510	COG0840	transmembrane signaling receptor activity
EYQ98_RS17515	COG0840	transmembrane signaling receptor activity
EYQ98_RS17520	COG0840	transmembrane signaling receptor activity
EYQ98_RS17535	COG0432	Pfam Uncharacterised protein family UPF0047
EYQ98_RS17540	COG0366	Alpha amylase catalytic
EYQ98_RS17555	COG5297	Belongs to the glycosyl hydrolase family 6
EYQ98_RS17560	COG1253	flavin adenine dinucleotide binding
EYQ98_RS17565	COG2738	Putative neutral zinc metallopeptidase
EYQ98_RS17580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYQ98_RS17590	COG2323	membrane
EYQ98_RS17595	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYQ98_RS17605	COG0166	Belongs to the GPI family
EYQ98_RS17610	COG1979	alcohol dehydrogenase
EYQ98_RS17615	COG2155	Conserved Protein
EYQ98_RS17620	COG1098	S1 RNA binding domain
EYQ98_RS17625	COG0436	Aminotransferase
EYQ98_RS17630	COG1522	sequence-specific DNA binding
EYQ98_RS17635	COG2267	carboxylic ester hydrolase activity
EYQ98_RS17650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYQ98_RS17665	COG5018	Exonuclease
EYQ98_RS17670	COG2814	Major facilitator Superfamily
EYQ98_RS17675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYQ98_RS17680	COG3011	Protein conserved in bacteria
EYQ98_RS17690	COG3290	protein histidine kinase activity
EYQ98_RS17695	COG4565	transcriptional regulatory protein
EYQ98_RS17705	COG1183	phosphatidylcholine synthase activity
EYQ98_RS17710	COG0586	Pfam SNARE associated Golgi protein
EYQ98_RS17715	COG0688	phosphatidylethanolamine metabolic process
EYQ98_RS17720	COG3493	citrate carrier protein
EYQ98_RS17730	COG2111	Na H antiporter
EYQ98_RS17730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYQ98_RS17735	COG2111	Na H antiporter
EYQ98_RS17740	COG1006	Multisubunit Na H antiporter MnhC subunit
EYQ98_RS17750	COG1863	multisubunit Na H antiporter MnhE subunit
EYQ98_RS17755	COG2212	antiporter activity
EYQ98_RS17760	COG1320	monovalent cation:proton antiporter activity
EYQ98_RS17765	COG2050	protein possibly involved in aromatic compounds catabolism
EYQ98_RS17770	COG2197	response regulator
EYQ98_RS17775	COG4585	Histidine kinase
EYQ98_RS17805	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EYQ98_RS17810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYQ98_RS17815	COG1335	isochorismatase
EYQ98_RS17820	COG5506	Protein of unknown function (DUF1694)
EYQ98_RS17835	COG0628	permease
EYQ98_RS17840	COG1959	2 iron, 2 sulfur cluster binding
EYQ98_RS17845	COG0657	acetylesterase activity
EYQ98_RS17855	COG1418	mRNA catabolic process
EYQ98_RS17860	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS17870	COG1511	domain protein
EYQ98_RS17875	COG0433	COG0433 Predicted ATPase
EYQ98_RS17875	COG1674	ftsk spoiiie
EYQ98_RS17880	COG4499	WXG100 protein secretion system (Wss), protein YukC
EYQ98_RS17885	COG5417	Belongs to the EsaB family
EYQ98_RS17890	COG4842	Belongs to the WXG100 family
EYQ98_RS17900	COG2508	Transcriptional regulator
EYQ98_RS17900	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EYQ98_RS17905	COG0686	Belongs to the AlaDH PNT family
EYQ98_RS17915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYQ98_RS17920	COG1268	BioY protein
EYQ98_RS17925	COG2056	Na+-H+ antiporter family
EYQ98_RS17930	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYQ98_RS17935	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EYQ98_RS17940	COG3584	3D domain protein
EYQ98_RS17950	COG1252	NADH dehydrogenase
EYQ98_RS17955	COG0492	ferredoxin-NADP+ reductase activity
EYQ98_RS17970	COG0456	acetyltransferase
EYQ98_RS17975	COG0316	Belongs to the HesB IscA family
EYQ98_RS17980	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYQ98_RS17985	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ98_RS17990	COG4844	belongs to the
EYQ98_RS17995	COG1252	NADH dehydrogenase
EYQ98_RS18000	COG5646	InterPro IPR014922
EYQ98_RS18010	COG0457	Tetratricopeptide repeat
EYQ98_RS18015	COG3479	Phenolic acid decarboxylase
EYQ98_RS18025	COG4837	Protein of unknown function (DUF1462)
EYQ98_RS18030	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYQ98_RS18035	COG1506	peptidase
EYQ98_RS18035	COG4946	Tricorn protease homolog
EYQ98_RS18035	COG0823	Involved in the tonB-independent uptake of proteins
EYQ98_RS18040	COG0083	homoserine kinase activity
EYQ98_RS18045	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYQ98_RS18050	COG0460	homoserine dehydrogenase
EYQ98_RS18060	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYQ98_RS18065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EYQ98_RS18070	COG0647	UMP catabolic process
EYQ98_RS18075	COG2445	Protein of unknown function DUF86
EYQ98_RS18080	COG4470	Protein conserved in bacteria
EYQ98_RS18105	COG0733	neurotransmitter:sodium symporter activity
EYQ98_RS18115	COG3377	Domain of unknown function (DUF1805)
EYQ98_RS18120	COG0737	Belongs to the 5'-nucleotidase family
EYQ98_RS18125	COG0730	response to heat
EYQ98_RS18130	COG1801	Protein of unknown function DUF72
EYQ98_RS18140	COG3226	Transcriptional regulator
EYQ98_RS18150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYQ98_RS18155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYQ98_RS18160	COG2508	Transcriptional regulator
EYQ98_RS18165	COG2814	Major facilitator Superfamily
EYQ98_RS18170	COG1288	antiporter activity
EYQ98_RS18175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYQ98_RS18180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYQ98_RS18185	COG2356	endonuclease I
EYQ98_RS18195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYQ98_RS18210	COG0457	Tetratricopeptide repeat
EYQ98_RS18215	COG0719	Fe-S assembly protein
EYQ98_RS18220	COG0822	iron-sulfur transferase activity
EYQ98_RS18225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYQ98_RS18230	COG0719	Fe-S assembly protein
EYQ98_RS18235	COG0396	ATPase activity
EYQ98_RS18245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYQ98_RS18250	COG1464	Belongs to the NlpA lipoprotein family
EYQ98_RS18255	COG2011	ABC-type metal ion transport system permease component
EYQ98_RS18260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYQ98_RS18270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYQ98_RS18275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EYQ98_RS18285	COG0509	glycine decarboxylation via glycine cleavage system
EYQ98_RS18290	COG1393	Belongs to the ArsC family
EYQ98_RS18295	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS18300	COG0183	Belongs to the thiolase family
EYQ98_RS18305	COG1024	Enoyl-CoA hydratase
EYQ98_RS18305	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYQ98_RS18320	COG5577	PFAM Coat F domain
EYQ98_RS18335	COG1120	ATPase activity
EYQ98_RS18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS18345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS18350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS18365	COG1686	Belongs to the peptidase S11 family
EYQ98_RS18370	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS18375	COG0783	Belongs to the Dps family
EYQ98_RS18380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYQ98_RS18385	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS18390	COG2205	protein histidine kinase activity
EYQ98_RS18390	COG2770	Histidine kinase
EYQ98_RS18395	COG1309	transcriptional regulator
EYQ98_RS18400	COG0114	fumarate hydratase activity
EYQ98_RS18410	COG0697	spore germination
EYQ98_RS18415	COG0814	amino acid
EYQ98_RS18430	COG2197	response regulator
EYQ98_RS18435	COG4585	Histidine kinase
EYQ98_RS18440	COG4758	membrane
EYQ98_RS18450	COG1842	Phage shock protein A
EYQ98_RS18455	COG4758	membrane
EYQ98_RS18460	COG4677	pectinesterase activity
EYQ98_RS18465	COG2096	Adenosyltransferase
EYQ98_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS18485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYQ98_RS18490	COG1120	ATPase activity
EYQ98_RS18495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS18500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS18505	COG1802	Transcriptional regulator
EYQ98_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS18515	COG2258	MOSC domain
EYQ98_RS18520	COG0583	DNA-binding transcription factor activity
EYQ98_RS18530	COG2721	sulfolactate sulfo-lyase activity
EYQ98_RS18535	COG0246	Mannitol dehydrogenase
EYQ98_RS18540	COG1609	Transcriptional regulator
EYQ98_RS18545	COG2211	Major facilitator Superfamily
EYQ98_RS18550	COG1904	glucuronate isomerase
EYQ98_RS18555	COG2205	protein histidine kinase activity
EYQ98_RS18560	COG0745	RESPONSE REGULATOR receiver
EYQ98_RS18565	COG1120	ATPase activity
EYQ98_RS18570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS18580	COG0531	amino acid
EYQ98_RS18590	COG1988	membrane-bound metal-dependent
EYQ98_RS18600	COG2814	Major facilitator Superfamily
EYQ98_RS18605	COG0656	L-ascorbic acid biosynthetic process
EYQ98_RS18610	COG1940	carbohydrate kinase activity
EYQ98_RS18615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYQ98_RS18625	COG3973	AAA domain
EYQ98_RS18630	COG2860	membrane
EYQ98_RS18635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EYQ98_RS18635	COG0456	acetyltransferase
EYQ98_RS18640	COG0456	acetyltransferase
EYQ98_RS18645	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EYQ98_RS18650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYQ98_RS18655	COG2217	Heavy metal translocating P-type atpase
EYQ98_RS18660	COG1653	transport
EYQ98_RS18665	COG1175	transmembrane transport
EYQ98_RS18670	COG0395	ABC-type sugar transport system, permease component
EYQ98_RS18675	COG1501	Belongs to the glycosyl hydrolase 31 family
EYQ98_RS18680	COG1472	Belongs to the glycosyl hydrolase 3 family
EYQ98_RS18685	COG1121	(ABC) transporter
EYQ98_RS18690	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYQ98_RS18695	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYQ98_RS18710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EYQ98_RS18710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYQ98_RS18715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS18715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS18715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYQ98_RS18730	COG2217	Heavy metal translocating P-type atpase
EYQ98_RS18735	COG2608	mercury ion transmembrane transporter activity
EYQ98_RS18740	COG1937	Protein conserved in bacteria
EYQ98_RS18745	COG0693	protein deglycase activity
EYQ98_RS18750	COG1349	DNA-binding transcription factor activity
EYQ98_RS18755	COG1070	Carbohydrate kinase
EYQ98_RS18760	COG4952	isomerase
EYQ98_RS18770	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS18770	COG3347	Dehydrogenase
EYQ98_RS18775	COG2814	Major facilitator Superfamily
EYQ98_RS18780	COG2814	Major facilitator Superfamily
EYQ98_RS18790	COG2124	cytochrome p450
EYQ98_RS18800	COG1846	Transcriptional regulator
EYQ98_RS18810	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS18815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYQ98_RS18820	COG1054	Belongs to the UPF0176 family
EYQ98_RS18830	COG1191	sigma factor activity
EYQ98_RS18840	COG2140	Oxalate decarboxylase
EYQ98_RS18905	COG5444	nuclease activity
EYQ98_RS18950	COG1705	Flagellar rod assembly protein muramidase FlgJ
EYQ98_RS18960	COG5280	Phage tail tape measure protein TP901
EYQ98_RS18960	COG3953	SLT domain
EYQ98_RS19020	COG1802	Transcriptional regulator
EYQ98_RS19020	COG4626	Terminase
EYQ98_RS19150	COG1396	sequence-specific DNA binding
EYQ98_RS19170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYQ98_RS19175	COG0557	exoribonuclease II activity
EYQ98_RS19180	COG1647	Serine aminopeptidase, S33
EYQ98_RS19185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYQ98_RS19190	COG2002	toxin-antitoxin pair type II binding
EYQ98_RS19195	COG1476	TRANSCRIPTIONal
EYQ98_RS19200	COG1396	sequence-specific DNA binding
EYQ98_RS19205	COG1396	sequence-specific DNA binding
EYQ98_RS19210	COG1174	glycine betaine transport
EYQ98_RS19215	COG1732	Glycine betaine
EYQ98_RS19220	COG1174	glycine betaine transport
EYQ98_RS19225	COG1125	glycine betaine transport
EYQ98_RS19225	COG0517	IMP dehydrogenase activity
EYQ98_RS19230	COG1510	regulation of RNA biosynthetic process
EYQ98_RS19235	COG2095	MarC family integral membrane protein
EYQ98_RS19240	COG3064	Membrane
EYQ98_RS19250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS19265	COG0693	protein deglycase activity
EYQ98_RS19270	COG0148	phosphopyruvate hydratase activity
EYQ98_RS19275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYQ98_RS19280	COG0149	triose-phosphate isomerase activity
EYQ98_RS19285	COG0126	phosphoglycerate kinase activity
EYQ98_RS19295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EYQ98_RS19300	COG2390	Transcriptional regulator
EYQ98_RS19305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ98_RS19310	COG1113	amino acid transport
EYQ98_RS19330	COG1556	Lactate utilization protein
EYQ98_RS19335	COG1139	Iron-sulfur cluster binding protein
EYQ98_RS19340	COG0247	lactate metabolic process
EYQ98_RS19345	COG2186	Transcriptional regulator
EYQ98_RS19350	COG1620	l-lactate permease
EYQ98_RS19355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EYQ98_RS19365	COG5039	Polysaccharide pyruvyl transferase
EYQ98_RS19370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYQ98_RS19375	COG0110	maltose O-acetyltransferase activity
EYQ98_RS19380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYQ98_RS19390	COG1216	Glycosyl transferase, family 2
EYQ98_RS19395	COG5039	Polysaccharide pyruvyl transferase
EYQ98_RS19400	COG1216	Glycosyl transferase, family 2
EYQ98_RS19410	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS19415	COG1215	transferase activity, transferring glycosyl groups
EYQ98_RS19420	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS19425	COG1086	Polysaccharide biosynthesis protein
EYQ98_RS19430	COG0489	protein tyrosine kinase activity
EYQ98_RS19435	COG3944	biosynthesis protein
EYQ98_RS19440	COG1396	sequence-specific DNA binding
EYQ98_RS19445	COG2249	NAD(P)H dehydrogenase (quinone) activity
EYQ98_RS19450	COG2271	Major facilitator Superfamily
EYQ98_RS19460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYQ98_RS19475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYQ98_RS19490	COG1902	pentaerythritol trinitrate reductase activity
EYQ98_RS19500	COG1621	beta-fructofuranosidase activity
EYQ98_RS19515	COG0740	serine-type endopeptidase activity
EYQ98_RS19520	COG1611	Belongs to the LOG family
EYQ98_RS19525	COG1694	Mazg nucleotide pyrophosphohydrolase
EYQ98_RS19530	COG1078	dGTPase activity
EYQ98_RS19535	COG0659	secondary active sulfate transmembrane transporter activity
EYQ98_RS19540	COG0288	reversible hydration of carbon dioxide
EYQ98_RS19545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ98_RS19550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYQ98_RS19555	COG0640	Transcriptional regulator
EYQ98_RS19565	COG2732	(Barnase) inhibitor
EYQ98_RS19570	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EYQ98_RS19575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS19585	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EYQ98_RS19590	COG1660	Displays ATPase and GTPase activities
EYQ98_RS19595	COG1051	belongs to the nudix hydrolase family
EYQ98_RS19605	COG0492	ferredoxin-NADP+ reductase activity
EYQ98_RS19610	COG0457	Tetratricopeptide repeat
EYQ98_RS19615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYQ98_RS19620	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYQ98_RS19620	COG0140	phosphoribosyl-ATP diphosphatase activity
EYQ98_RS19625	COG0107	imidazoleglycerol-phosphate synthase activity
EYQ98_RS19630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYQ98_RS19635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYQ98_RS19640	COG0131	Imidazoleglycerol-phosphate dehydratase
EYQ98_RS19645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYQ98_RS19650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYQ98_RS19655	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYQ98_RS19660	COG4990	cell redox homeostasis
EYQ98_RS19665	COG5297	Belongs to the glycosyl hydrolase family 6
EYQ98_RS19670	COG0110	maltose O-acetyltransferase activity
EYQ98_RS19675	COG0546	phosphoglycolate phosphatase activity
EYQ98_RS19680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYQ98_RS19685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYQ98_RS19690	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYQ98_RS19695	COG1846	Transcriptional regulator
EYQ98_RS19700	COG2814	Major facilitator Superfamily
EYQ98_RS19705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EYQ98_RS19710	COG1950	PFAM Membrane protein of
EYQ98_RS19715	COG1983	PspC domain protein
EYQ98_RS19720	COG3595	metallopeptidase activity
EYQ98_RS19750	COG0556	nucleotide-excision repair
EYQ98_RS19755	COG4897	Protein conserved in bacteria
EYQ98_RS19765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYQ98_RS19775	COG0793	Belongs to the peptidase S41A family
EYQ98_RS19775	COG3409	Peptidoglycan-binding domain 1 protein
EYQ98_RS19780	COG0473	3-isopropylmalate dehydrogenase activity
EYQ98_RS19785	COG3883	PFAM NLP P60 protein
EYQ98_RS19785	COG0791	NLP P60 protein
EYQ98_RS19790	COG2177	Part of the ABC transporter FtsEX involved in
EYQ98_RS19795	COG2884	Cell division ATP-binding protein ftsE
EYQ98_RS19805	COG2010	Cytochrome c
EYQ98_RS19810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS19820	COG0653	protein targeting
EYQ98_RS19825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EYQ98_RS19840	COG1516	flagellar protein fliS
EYQ98_RS19845	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EYQ98_RS19850	COG1334	flagellar protein FlaG
EYQ98_RS19855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYQ98_RS19860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EYQ98_RS19865	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EYQ98_RS19875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYQ98_RS19880	COG1256	bacterial-type flagellum assembly
EYQ98_RS19880	COG4786	Flagellar basal body rod
EYQ98_RS19885	COG3418	PFAM FlgN family protein
EYQ98_RS19890	COG2747	anti-sigma28 factor FlgM
EYQ98_RS19900	COG1040	competence protein
EYQ98_RS19910	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EYQ98_RS19915	COG1307	EDD domain protein, DegV family
EYQ98_RS19920	COG2197	response regulator
EYQ98_RS19925	COG4585	Histidine kinase
EYQ98_RS19930	COG1739	Uncharacterized protein family UPF0029
EYQ98_RS19935	COG1316	TRANSCRIPTIONal
EYQ98_RS19945	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYQ98_RS19950	COG0438	transferase activity, transferring glycosyl groups
EYQ98_RS19955	COG1215	transferase activity, transferring glycosyl groups
EYQ98_RS19960	COG3206	protein involved in exopolysaccharide biosynthesis
EYQ98_RS19965	COG3307	-O-antigen
EYQ98_RS19970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYQ98_RS19975	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EYQ98_RS19985	COG2244	polysaccharide biosynthetic process
EYQ98_RS19995	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYQ98_RS19995	COG2247	cell wall binding repeat
EYQ98_RS20000	COG2247	cell wall binding repeat
EYQ98_RS20000	COG2385	sporulation resulting in formation of a cellular spore
EYQ98_RS20010	COG1316	TRANSCRIPTIONal
EYQ98_RS20015	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EYQ98_RS20020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYQ98_RS20025	COG1134	teichoic acid transport
EYQ98_RS20030	COG1682	transport, permease protein
EYQ98_RS20035	COG0463	Glycosyl transferase, family 2
EYQ98_RS20035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ98_RS20040	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ98_RS20045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYQ98_RS20050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EYQ98_RS20055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYQ98_RS20065	COG1482	cell wall glycoprotein biosynthetic process
EYQ98_RS20085	COG0800	Aldolase
EYQ98_RS20090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYQ98_RS20095	COG1609	Transcriptional regulator
EYQ98_RS20100	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EYQ98_RS20105	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS20110	COG1063	alcohol dehydrogenase
EYQ98_RS20115	COG2814	Major facilitator Superfamily
EYQ98_RS20120	COG1316	TRANSCRIPTIONal
EYQ98_RS20125	COG0561	phosphatase activity
EYQ98_RS20130	COG0791	NLP P60 protein
EYQ98_RS20135	COG2843	Capsule synthesis protein
EYQ98_RS20145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYQ98_RS20150	COG1609	Transcriptional regulator
EYQ98_RS20155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYQ98_RS20160	COG1869	D-ribose catabolic process
EYQ98_RS20165	COG1129	ABC transporter
EYQ98_RS20170	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYQ98_RS20175	COG1879	ABC-type sugar transport system periplasmic component
EYQ98_RS20185	COG3527	Alpha-acetolactate decarboxylase
EYQ98_RS20190	COG0028	Belongs to the TPP enzyme family
EYQ98_RS20195	COG0583	DNA-binding transcription factor activity
EYQ98_RS20200	COG0405	Gamma-glutamyltransferase
EYQ98_RS20205	COG1522	sequence-specific DNA binding
EYQ98_RS20210	COG2059	Chromate
EYQ98_RS20215	COG2059	Chromate
EYQ98_RS20220	COG4464	protein tyrosine phosphatase activity
EYQ98_RS20225	COG3944	biosynthesis protein
EYQ98_RS20235	COG4715	Zinc finger, swim domain protein
EYQ98_RS20240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYQ98_RS20245	COG0561	phosphatase activity
EYQ98_RS20250	COG1349	DNA-binding transcription factor activity
EYQ98_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS20270	COG3732	PTS system glucitol sorbitol-specific
EYQ98_RS20290	COG0629	single-stranded DNA binding
EYQ98_RS20305	COG1970	mechanosensitive ion channel activity
EYQ98_RS20310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYQ98_RS20315	COG4786	Flagellar basal body rod
EYQ98_RS20320	COG4786	Flagellar basal body rod
EYQ98_RS20325	COG1077	Cell shape determining protein MreB Mrl
EYQ98_RS20330	COG1609	Transcriptional regulator
EYQ98_RS20340	COG1846	Transcriptional regulator
EYQ98_RS20345	COG2814	Major facilitator Superfamily
EYQ98_RS20350	COG0671	phosphoesterase, PA-phosphatase related
EYQ98_RS20355	COG1227	inorganic diphosphatase activity
EYQ98_RS20360	COG3546	catalase activity
EYQ98_RS20365	COG3361	conserved protein (COG2071)
EYQ98_RS20370	COG0517	IMP dehydrogenase activity
EYQ98_RS20375	COG0598	Magnesium transport protein CorA
EYQ98_RS20380	COG1253	flavin adenine dinucleotide binding
EYQ98_RS20385	COG0004	ammonium transporteR
EYQ98_RS20390	COG0347	Belongs to the P(II) protein family
EYQ98_RS20395	COG0740	serine-type endopeptidase activity
EYQ98_RS20405	COG0739	heme binding
EYQ98_RS20410	COG1247	-acetyltransferase
EYQ98_RS20420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYQ98_RS20425	COG0477	Major facilitator Superfamily
EYQ98_RS20430	COG3251	PFAM MbtH domain protein
EYQ98_RS20435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYQ98_RS20440	COG3433	isochorismatase activity
EYQ98_RS20440	COG1535	isochorismatase
EYQ98_RS20445	COG1021	2,3-dihydroxybenzoate-AMP ligase
EYQ98_RS20450	COG1169	isochorismate synthase
EYQ98_RS20455	COG1028	Short-chain dehydrogenase reductase Sdr
EYQ98_RS20460	COG2819	hydrolase of the alpha beta superfamily
EYQ98_RS20465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS20470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYQ98_RS20475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS20480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EYQ98_RS20480	COG2207	Transcriptional regulator
EYQ98_RS20490	COG2910	NAD(P)H-binding
EYQ98_RS20495	COG1959	2 iron, 2 sulfur cluster binding
EYQ98_RS20505	COG1994	Peptidase M50
EYQ98_RS20510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYQ98_RS20515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYQ98_RS20520	COG2223	nitrite transmembrane transporter activity
EYQ98_RS20525	COG3383	formate dehydrogenase (NAD+) activity
EYQ98_RS20530	COG2304	oxidoreductase activity
EYQ98_RS20535	COG2304	oxidoreductase activity
EYQ98_RS20540	COG2385	sporulation resulting in formation of a cellular spore
EYQ98_RS20545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYQ98_RS20555	COG4836	Membrane
EYQ98_RS20565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYQ98_RS20570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYQ98_RS20575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYQ98_RS20580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYQ98_RS20585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYQ98_RS20590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYQ98_RS20610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYQ98_RS20615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYQ98_RS20625	COG0698	ribose 5-phosphate isomerase
EYQ98_RS20630	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYQ98_RS20635	COG1971	Probably functions as a manganese efflux pump
EYQ98_RS20640	COG0009	L-threonylcarbamoyladenylate synthase
EYQ98_RS20645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EYQ98_RS20655	COG0738	Major facilitator superfamily
EYQ98_RS20660	COG0673	inositol 2-dehydrogenase activity
EYQ98_RS20665	COG0561	phosphatase activity
EYQ98_RS20670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYQ98_RS20675	COG1609	Transcriptional regulator
EYQ98_RS20680	COG2890	protein-(glutamine-N5) methyltransferase activity
EYQ98_RS20685	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYQ98_RS20690	COG0346	lactoylglutathione lyase activity
EYQ98_RS20695	COG0789	Transcriptional regulator
EYQ98_RS20700	COG0679	Auxin Efflux Carrier
EYQ98_RS20705	COG0281	malic enzyme
EYQ98_RS20710	COG1435	thymidine kinase activity
EYQ98_RS20715	COG0254	rRNA binding
EYQ98_RS20720	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYQ98_RS20725	COG1494	fructose-1,6-bisphosphatase
EYQ98_RS20730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYQ98_RS20735	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYQ98_RS20740	COG0191	fructose-bisphosphate aldolase activity
EYQ98_RS20745	COG2204	response regulator
EYQ98_RS20750	COG4821	SIS domain
EYQ98_RS20755	COG0504	CTP synthase activity
EYQ98_RS20760	COG3343	RNA polymerase activity
EYQ98_RS20765	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS20770	COG1960	acyl-CoA dehydrogenase activity
EYQ98_RS20775	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYQ98_RS20780	COG0183	Belongs to the thiolase family
EYQ98_RS20785	COG2181	nitrate reductase activity
EYQ98_RS20785	COG0247	lactate metabolic process
EYQ98_RS20790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYQ98_RS20800	COG0018	arginyl-trna synthetase
EYQ98_RS20805	COG4506	Protein conserved in bacteria
EYQ98_RS20810	COG0010	Belongs to the arginase family
EYQ98_RS20815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYQ98_RS20840	COG1994	Peptidase M50
EYQ98_RS20845	COG1942	4-Oxalocrotonate Tautomerase
EYQ98_RS20855	COG3465	dGTPase activity
EYQ98_RS20860	COG1078	dGTPase activity
EYQ98_RS20865	COG4844	belongs to the
EYQ98_RS20890	COG2814	Major facilitator Superfamily
EYQ98_RS20915	COG1414	Transcriptional regulator
EYQ98_RS20925	COG0280	phosphate acetyltransferase
EYQ98_RS20930	COG3253	May function as heme-dependent peroxidase
EYQ98_RS20945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYQ98_RS20965	COG1131	(ABC) transporter
EYQ98_RS20980	COG2363	Small membrane protein
EYQ98_RS20985	COG2233	PERMEase
EYQ98_RS20995	COG1012	belongs to the aldehyde dehydrogenase family
EYQ98_RS21000	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYQ98_RS21005	COG1216	Glycosyl transferase, family 2
EYQ98_RS21010	COG0351	phosphomethylpyrimidine kinase
EYQ98_RS21020	COG1621	beta-fructofuranosidase activity
EYQ98_RS21025	COG1263	PTS System
EYQ98_RS21025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS21030	COG3711	transcriptional antiterminator
EYQ98_RS21050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYQ98_RS21055	COG0778	Nitroreductase
EYQ98_RS21060	COG1473	amidohydrolase
EYQ98_RS21065	COG0772	Belongs to the SEDS family
EYQ98_RS21070	COG0772	Belongs to the SEDS family
EYQ98_RS21075	COG3314	Sporulation integral membrane protein YlbJ
EYQ98_RS21095	COG0456	acetyltransferase
EYQ98_RS21130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYQ98_RS21140	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYQ98_RS21145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYQ98_RS21150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYQ98_RS21170	COG3162	membrane
EYQ98_RS21175	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ98_RS21180	COG1070	Carbohydrate kinase
EYQ98_RS21185	COG2115	Belongs to the xylose isomerase family
EYQ98_RS21195	COG0352	thiamine-phosphate diphosphorylase activity
EYQ98_RS21200	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EYQ98_RS21205	COG0583	DNA-binding transcription factor activity
EYQ98_RS21220	COG1380	Effector of murein hydrolase LrgA
EYQ98_RS21225	COG1346	cytolysis
EYQ98_RS21235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYQ98_RS21240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYQ98_RS21245	COG0346	lactoylglutathione lyase activity
EYQ98_RS21250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYQ98_RS21255	COG1442	glycosyl transferase family 8
EYQ98_RS21265	COG4585	Histidine kinase
EYQ98_RS21270	COG2197	response regulator
EYQ98_RS21275	COG2409	Drug exporters of the RND superfamily
EYQ98_RS21280	COG5522	Integral membrane protein (intg_mem_TP0381)
EYQ98_RS21285	COG2271	Major facilitator Superfamily
EYQ98_RS21290	COG4948	Mandelate Racemase Muconate Lactonizing
EYQ98_RS21295	COG0800	Aldolase
EYQ98_RS21300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYQ98_RS21310	COG2234	aminopeptidase activity
EYQ98_RS21315	COG0477	Major facilitator Superfamily
EYQ98_RS21325	COG2357	RelA SpoT domain protein
EYQ98_RS21340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYQ98_RS21345	COG1696	Membrane protein involved in D-alanine export
EYQ98_RS21350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYQ98_RS21355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EYQ98_RS21360	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYQ98_RS21365	COG2814	Major facilitator Superfamily
EYQ98_RS21370	COG1486	melibiose metabolic process
EYQ98_RS21375	COG1447	Phosphotransferase system cellobiose-specific component IIA
EYQ98_RS21380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS21385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS21390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYQ98_RS21390	COG3711	transcriptional antiterminator
EYQ98_RS21395	COG2094	Belongs to the DNA glycosylase MPG family
EYQ98_RS21405	COG0372	Belongs to the citrate synthase family
EYQ98_RS21410	COG2079	MmgE PrpD family protein
EYQ98_RS21415	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EYQ98_RS21430	COG1132	(ABC) transporter
EYQ98_RS21435	COG2755	lipolytic protein G-D-S-L family
EYQ98_RS21450	COG2814	Major facilitator Superfamily
EYQ98_RS21455	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYQ98_RS21460	COG1131	(ABC) transporter
EYQ98_RS21480	COG1595	DNA-templated transcription, initiation
EYQ98_RS21485	COG2814	Major facilitator Superfamily
EYQ98_RS21490	COG0753	catalase activity
EYQ98_RS21495	COG0753	catalase activity
EYQ98_RS21500	COG0735	belongs to the Fur family
EYQ98_RS21505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYQ98_RS21510	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EYQ98_RS21515	COG1131	(ABC) transporter
EYQ98_RS21530	COG1131	(ABC) transporter
EYQ98_RS21585	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYQ98_RS21590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYQ98_RS21595	COG4988	ABC transporter
EYQ98_RS21600	COG1294	oxidase, subunit
EYQ98_RS21605	COG1271	oxidase subunit
EYQ98_RS21615	COG2116	formate transmembrane transporter activity
EYQ98_RS21625	COG0281	malic enzyme
EYQ98_RS21630	COG1757	Na H antiporter
EYQ98_RS21635	COG1027	Aspartate ammonia-lyase
EYQ98_RS21640	COG0252	asparaginase activity
EYQ98_RS21645	COG1396	sequence-specific DNA binding
EYQ98_RS21650	COG2706	6-phosphogluconolactonase activity
EYQ98_RS21660	COG2205	protein histidine kinase activity
EYQ98_RS21670	COG1136	(ABC) transporter
EYQ98_RS21675	COG0577	efflux transmembrane transporter activity
EYQ98_RS21680	COG5294	Protein conserved in bacteria
EYQ98_RS21690	COG0726	polysaccharide deacetylase
EYQ98_RS21695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYQ98_RS21705	COG1215	transferase activity, transferring glycosyl groups
EYQ98_RS21710	COG3493	citrate carrier protein
EYQ98_RS21715	COG0584	glycerophosphoryl diester phosphodiesterase
EYQ98_RS21730	COG1368	sulfuric ester hydrolase activity
EYQ98_RS21740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYQ98_RS21760	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYQ98_RS21770	COG0549	Belongs to the carbamate kinase family
EYQ98_RS21780	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS21785	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EYQ98_RS21795	COG1595	DNA-templated transcription, initiation
EYQ98_RS21820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYQ98_RS21825	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYQ98_RS21835	COG1621	beta-fructofuranosidase activity
EYQ98_RS21840	COG2223	nitrite transmembrane transporter activity
EYQ98_RS21845	COG1609	Transcriptional regulator
EYQ98_RS21860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EYQ98_RS21865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYQ98_RS21870	COG0463	Glycosyl transferase, family 2
EYQ98_RS21875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYQ98_RS21900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EYQ98_RS21915	COG2723	6-phospho-beta-galactosidase activity
EYQ98_RS21920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYQ98_RS21920	COG2190	(PTS) system
EYQ98_RS21920	COG1263	PTS System