locus-tag	class	description
LXN06_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LXN06_RS00010	COG0592	DNA-directed DNA polymerase activity
LXN06_RS00015	COG2501	S4 domain
LXN06_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LXN06_RS00030	COG0187	DNA topoisomerase II activity
LXN06_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXN06_RS00070	COG0516	GMP reductase activity
LXN06_RS00070	COG0517	IMP dehydrogenase activity
LXN06_RS00075	COG1686	Belongs to the peptidase S11 family
LXN06_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LXN06_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LXN06_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LXN06_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
LXN06_RS00100	COG2610	gluconate transmembrane transporter activity
LXN06_RS00105	COG3835	regulator
LXN06_RS00120	COG1428	Deoxynucleoside kinase
LXN06_RS00125	COG1428	Deoxynucleoside kinase
LXN06_RS00130	COG1388	LysM domain
LXN06_RS00130	COG3858	chitin binding
LXN06_RS00135	COG1335	isochorismatase
LXN06_RS00140	COG0590	tRNA wobble adenosine to inosine editing
LXN06_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LXN06_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LXN06_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LXN06_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LXN06_RS00210	COG3853	Toxic anion resistance protein (TelA)
LXN06_RS00215	COG1982	Orn Lys Arg decarboxylase major
LXN06_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LXN06_RS00225	COG3870	Protein conserved in bacteria
LXN06_RS00230	COG1728	Protein conserved in bacteria
LXN06_RS00235	COG0470	DNA polymerase III
LXN06_RS00240	COG1774	PSP1 C-terminal conserved region
LXN06_RS00245	COG4467	Involved in initiation control of chromosome replication
LXN06_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LXN06_RS00255	COG2827	Endonuclease containing a URI domain
LXN06_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LXN06_RS00265	COG2002	toxin-antitoxin pair type II binding
LXN06_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXN06_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXN06_RS00275	COG0084	hydrolase, TatD family'
LXN06_RS00280	COG3583	domain protein
LXN06_RS00280	COG3584	3D domain protein
LXN06_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LXN06_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LXN06_RS00300	COG4466	Protein conserved in bacteria
LXN06_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LXN06_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXN06_RS00320	COG0251	oxidation-reduction process
LXN06_RS00325	COG2088	sporulation resulting in formation of a cellular spore
LXN06_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LXN06_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LXN06_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LXN06_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
LXN06_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LXN06_RS00360	COG2002	toxin-antitoxin pair type II binding
LXN06_RS00365	COG2244	polysaccharide biosynthetic process
LXN06_RS00370	COG3956	TIGRFAM MazG family protein
LXN06_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LXN06_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LXN06_RS00395	COG1098	S1 RNA binding domain
LXN06_RS00410	COG2208	phosphoserine phosphatase activity
LXN06_RS00415	COG2304	oxidoreductase activity
LXN06_RS00420	COG0515	serine threonine protein kinase
LXN06_RS00425	COG0037	tRNA processing
LXN06_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LXN06_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXN06_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LXN06_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LXN06_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXN06_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXN06_RS00460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXN06_RS00465	COG0512	Glutamine amidotransferase of anthranilate synthase
LXN06_RS00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXN06_RS00475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LXN06_RS00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LXN06_RS00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LXN06_RS00490	COG1396	sequence-specific DNA binding
LXN06_RS00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LXN06_RS00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LXN06_RS00580	COG4463	regulation of RNA biosynthetic process
LXN06_RS00585	COG3880	PFAM UvrB UvrC protein
LXN06_RS00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LXN06_RS00595	COG0542	response to heat
LXN06_RS00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LXN06_RS00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LXN06_RS00610	COG4956	integral membrane protein (PIN domain superfamily)
LXN06_RS00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LXN06_RS00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LXN06_RS00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LXN06_RS00630	COG1045	serine acetyltransferase
LXN06_RS00635	COG0215	cysteine-tRNA ligase activity
LXN06_RS00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXN06_RS00650	COG3688	RNA-binding protein containing a PIN domain
LXN06_RS00660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LXN06_RS00670	COG0250	Participates in transcription elongation, termination and antitermination
LXN06_RS00675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LXN06_RS00680	COG0081	regulation of translation
LXN06_RS00685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LXN06_RS00690	COG0222	ribosome binding
LXN06_RS00695	COG2813	Specifically methylates the guanine in position
LXN06_RS00700	COG0085	RNA polymerase activity
LXN06_RS00705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LXN06_RS00710	COG1358	cellular component organization or biogenesis
LXN06_RS00715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LXN06_RS00720	COG0049	tRNA binding
LXN06_RS00725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LXN06_RS00730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LXN06_RS00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LXN06_RS00745	COG0088	Forms part of the polypeptide exit tunnel
LXN06_RS00750	COG0089	rRNA binding
LXN06_RS00755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LXN06_RS00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LXN06_RS00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LXN06_RS00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LXN06_RS00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LXN06_RS00780	COG0255	Belongs to the universal ribosomal protein uL29 family
LXN06_RS00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LXN06_RS00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LXN06_RS00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LXN06_RS00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LXN06_RS00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LXN06_RS00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LXN06_RS00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LXN06_RS00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LXN06_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LXN06_RS00830	COG1841	ribosomal large subunit assembly
LXN06_RS00835	COG0200	Binds to the 23S rRNA
LXN06_RS00840	COG0201	protein transport
LXN06_RS00845	COG0563	adenylate kinase activity
LXN06_RS00850	COG0024	Methionine aminopeptidase
LXN06_RS00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
LXN06_RS00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LXN06_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LXN06_RS00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LXN06_RS00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LXN06_RS00880	COG0202	RNA polymerase activity
LXN06_RS00885	COG0203	ribosomal protein L17
LXN06_RS00890	COG1122	ATPase activity
LXN06_RS00895	COG1122	ATPase activity
LXN06_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LXN06_RS00905	COG0101	tRNA pseudouridine synthase activity
LXN06_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LXN06_RS00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LXN06_RS00920	COG2318	DinB family
LXN06_RS00930	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXN06_RS00935	COG0489	protein tyrosine kinase activity
LXN06_RS00945	COG2194	sulfuric ester hydrolase activity
LXN06_RS00950	COG0726	polysaccharide deacetylase
LXN06_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXN06_RS00995	COG0385	Bile acid
LXN06_RS01010	COG3876	Protein conserved in bacteria
LXN06_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
LXN06_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXN06_RS01025	COG1263	PTS System
LXN06_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS01030	COG1737	Transcriptional regulator
LXN06_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LXN06_RS01040	COG1683	Conserved Protein
LXN06_RS01075	COG1595	DNA-templated transcription, initiation
LXN06_RS01080	COG5662	AntiSigma factor
LXN06_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LXN06_RS01090	COG4856	YbbR-like protein
LXN06_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXN06_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LXN06_RS01130	COG1725	Transcriptional regulator
LXN06_RS01135	COG0640	Transcriptional regulator
LXN06_RS01140	COG2814	Major facilitator Superfamily
LXN06_RS01150	COG1132	(ABC) transporter
LXN06_RS01155	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXN06_RS01180	COG1011	Hydrolase
LXN06_RS01200	COG2211	Major facilitator Superfamily
LXN06_RS01220	COG1331	Highly conserved protein containing a thioredoxin domain
LXN06_RS01230	COG1733	regulation of RNA biosynthetic process
LXN06_RS01235	COG0596	Alpha beta hydrolase
LXN06_RS01245	COG4122	O-methyltransferase activity
LXN06_RS01250	COG0477	Major facilitator Superfamily
LXN06_RS01275	COG1283	sodium-dependent phosphate transmembrane transporter activity
LXN06_RS01280	COG4682	membrane
LXN06_RS01300	COG3409	Peptidoglycan-binding domain 1 protein
LXN06_RS01310	COG0697	spore germination
LXN06_RS01315	COG1917	Cupin 2, conserved barrel domain protein
LXN06_RS01315	COG2207	Transcriptional regulator
LXN06_RS01340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXN06_RS01350	COG0371	Dehydrogenase
LXN06_RS01370	COG4257	antibiotic catabolic process
LXN06_RS01380	COG0833	amino acid
LXN06_RS01385	COG2040	homocysteine
LXN06_RS01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS01395	COG1263	PTS System
LXN06_RS01395	COG2190	(PTS) system
LXN06_RS01400	COG0789	Transcriptional regulator
LXN06_RS01405	COG2323	membrane
LXN06_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXN06_RS01410	COG4451	ribulose bisphosphate carboxylase, small
LXN06_RS01425	COG2205	protein histidine kinase activity
LXN06_RS01430	COG1115	amino acid carrier protein
LXN06_RS01435	COG2066	Belongs to the glutaminase family
LXN06_RS01440	COG4191	Histidine kinase
LXN06_RS01445	COG0784	Response regulator, receiver
LXN06_RS01470	COG3540	Alkaline phosphatase
LXN06_RS01475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXN06_RS01480	COG0805	protein transport
LXN06_RS01485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXN06_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS01495	COG2271	Major facilitator Superfamily
LXN06_RS01500	COG4948	Mandelate Racemase Muconate Lactonizing
LXN06_RS01505	COG2186	Transcriptional regulator
LXN06_RS01510	COG2721	sulfolactate sulfo-lyase activity
LXN06_RS01530	COG0745	RESPONSE REGULATOR receiver
LXN06_RS01535	COG2205	protein histidine kinase activity
LXN06_RS01540	COG1131	(ABC) transporter
LXN06_RS01565	COG3173	Aminoglycoside phosphotransferase
LXN06_RS01570	COG1846	Transcriptional regulator
LXN06_RS01575	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS01595	COG0789	Transcriptional regulator
LXN06_RS01630	COG0693	protein deglycase activity
LXN06_RS01635	COG0697	spore germination
LXN06_RS01640	COG1714	RDD family
LXN06_RS01645	COG1405	negative regulation of cell septum assembly
LXN06_RS01645	COG3012	SEC-C Motif Domain Protein
LXN06_RS01650	COG1131	(ABC) transporter
LXN06_RS01675	COG0583	DNA-binding transcription factor activity
LXN06_RS01680	COG1942	4-Oxalocrotonate Tautomerase
LXN06_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS01700	COG1288	antiporter activity
LXN06_RS01710	COG0252	asparaginase activity
LXN06_RS01715	COG0456	acetyltransferase
LXN06_RS01725	COG1164	Oligoendopeptidase f
LXN06_RS01730	COG2261	transglycosylase associated protein
LXN06_RS01740	COG0247	lactate metabolic process
LXN06_RS01745	COG0277	FAD linked oxidase domain protein
LXN06_RS01750	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS01755	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXN06_RS01760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS01765	COG1486	melibiose metabolic process
LXN06_RS01770	COG2188	Transcriptional regulator
LXN06_RS01775	COG3394	polysaccharide catabolic process
LXN06_RS01790	COG3591	Belongs to the peptidase S1B family
LXN06_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS01805	COG1595	DNA-templated transcription, initiation
LXN06_RS01815	COG3773	Cell wall hydrolase
LXN06_RS01820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXN06_RS01825	COG3883	PFAM NLP P60 protein
LXN06_RS01825	COG0791	NLP P60 protein
LXN06_RS01835	COG1131	(ABC) transporter
LXN06_RS01840	COG1309	transcriptional regulator
LXN06_RS01860	COG2310	stress, protein
LXN06_RS01865	COG2310	stress, protein
LXN06_RS01870	COG2310	stress, protein
LXN06_RS01875	COG0861	Integral membrane protein TerC family
LXN06_RS01895	COG3853	Toxic anion resistance protein (TelA)
LXN06_RS01900	COG0785	Cytochrome C biogenesis protein
LXN06_RS01910	COG0789	Transcriptional regulator
LXN06_RS01915	COG2223	nitrite transmembrane transporter activity
LXN06_RS01925	COG0039	L-malate dehydrogenase activity
LXN06_RS01930	COG1620	l-lactate permease
LXN06_RS01935	COG1280	lysine exporter protein (LysE YggA)
LXN06_RS01940	COG1113	amino acid transport
LXN06_RS01945	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LXN06_RS01950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LXN06_RS01955	COG3541	Predicted nucleotidyltransferase
LXN06_RS01960	COG0506	proline dehydrogenase activity
LXN06_RS01965	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS01970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS01975	COG2508	Transcriptional regulator
LXN06_RS01980	COG3689	TIGRFAM TIGR03943 family protein
LXN06_RS01985	COG0701	Predicted permease
LXN06_RS01990	COG3458	cephalosporin-C deacetylase activity
LXN06_RS02010	COG0765	amino acid transport
LXN06_RS02015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXN06_RS02020	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS02030	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS02040	COG3209	COG3209 Rhs family protein
LXN06_RS02055	COG0840	transmembrane signaling receptor activity
LXN06_RS02055	COG3290	protein histidine kinase activity
LXN06_RS02060	COG5444	nuclease activity
LXN06_RS02085	COG1176	ABC-type spermidine putrescine transport system, permease component I
LXN06_RS02090	COG1177	transmembrane transport
LXN06_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS02100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS02105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS02110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LXN06_RS02115	COG0697	spore germination
LXN06_RS02120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXN06_RS02130	COG2819	hydrolase of the alpha beta superfamily
LXN06_RS02135	COG2207	Transcriptional regulator
LXN06_RS02135	COG3708	Transcriptional regulator
LXN06_RS02140	COG2364	Membrane
LXN06_RS02150	COG1131	(ABC) transporter
LXN06_RS02175	COG0840	transmembrane signaling receptor activity
LXN06_RS02195	COG1126	abc transporter atp-binding protein
LXN06_RS02200	COG0765	amino acid transport
LXN06_RS02205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXN06_RS02210	COG3829	transcription factor binding
LXN06_RS02215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXN06_RS02220	COG0833	amino acid
LXN06_RS02225	COG0010	Belongs to the arginase family
LXN06_RS02230	COG0583	DNA-binding transcription factor activity
LXN06_RS02235	COG0163	prenyltransferase activity
LXN06_RS02240	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LXN06_RS02290	COG5444	nuclease activity
LXN06_RS02310	COG2972	Histidine kinase
LXN06_RS02315	COG4753	response regulator
LXN06_RS02315	COG2207	Transcriptional regulator
LXN06_RS02320	COG4213	ABC transporter substrate-binding protein
LXN06_RS02330	COG4214	carbohydrate transport
LXN06_RS02335	COG2271	Major facilitator Superfamily
LXN06_RS02340	COG0456	acetyltransferase
LXN06_RS02340	COG1846	Transcriptional regulator
LXN06_RS02345	COG1874	Beta-galactosidase
LXN06_RS02350	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
LXN06_RS02355	COG3104	oligopeptide transport
LXN06_RS02360	COG5434	Belongs to the glycosyl hydrolase 28 family
LXN06_RS02370	COG0697	spore germination
LXN06_RS02380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LXN06_RS02385	COG0789	Transcriptional regulator
LXN06_RS02390	COG1136	(ABC) transporter
LXN06_RS02395	COG0577	efflux transmembrane transporter activity
LXN06_RS02400	COG0745	RESPONSE REGULATOR receiver
LXN06_RS02405	COG3850	Histidine kinase
LXN06_RS02405	COG5002	protein histidine kinase activity
LXN06_RS02410	COG0840	transmembrane signaling receptor activity
LXN06_RS02415	COG0527	aspartate kinase activity
LXN06_RS02420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS02425	COG4605	iron ion homeostasis
LXN06_RS02430	COG4604	ABC transporter, ATP-binding protein
LXN06_RS02435	COG4607	ABC-type enterochelin transport system periplasmic component
LXN06_RS02440	COG2814	Major facilitator Superfamily
LXN06_RS02445	COG1309	transcriptional regulator
LXN06_RS02455	COG0778	Nitroreductase
LXN06_RS02460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LXN06_RS02465	COG0640	Transcriptional regulator
LXN06_RS02470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXN06_RS02475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LXN06_RS02480	COG0531	amino acid
LXN06_RS02485	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS02490	COG0697	spore germination
LXN06_RS02500	COG4549	nuclear export factor GLE1
LXN06_RS02505	COG1276	copper resistance
LXN06_RS02505	COG2372	response to copper ion
LXN06_RS02510	COG1349	DNA-binding transcription factor activity
LXN06_RS02515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXN06_RS02520	COG0243	molybdopterin cofactor binding
LXN06_RS02525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXN06_RS02530	COG2146	nitrite reductase [NAD(P)H] activity
LXN06_RS02535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXN06_RS02535	COG1587	Uroporphyrinogen-III synthase
LXN06_RS02540	COG1802	Transcriptional regulator
LXN06_RS02545	COG0471	metal ion transport
LXN06_RS02550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXN06_RS02560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS02575	COG3959	Transketolase, thiamine diphosphate binding domain
LXN06_RS02580	COG3958	Transketolase
LXN06_RS02585	COG0561	phosphatase activity
LXN06_RS02590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LXN06_RS02595	COG1914	H( )-stimulated, divalent metal cation uptake system
LXN06_RS02600	COG4336	lyase activity
LXN06_RS02605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LXN06_RS02610	COG1984	allophanate hydrolase subunit 2
LXN06_RS02615	COG1414	Transcriptional regulator
LXN06_RS02620	COG2755	lipolytic protein G-D-S-L family
LXN06_RS02625	COG2213	PTS system mannitol-specific
LXN06_RS02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS02635	COG0246	Mannitol dehydrogenase
LXN06_RS02640	COG3711	transcriptional antiterminator
LXN06_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS02650	COG1917	Cupin 2, conserved barrel domain protein
LXN06_RS02660	COG3871	stress protein (general stress protein 26)
LXN06_RS02675	COG2814	Major facilitator Superfamily
LXN06_RS02685	COG1522	sequence-specific DNA binding
LXN06_RS02690	COG0551	DNA topoisomerase type I activity
LXN06_RS02690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXN06_RS02695	COG0287	Prephenate dehydrogenase
LXN06_RS02700	COG0512	Glutamine amidotransferase of anthranilate synthase
LXN06_RS02700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXN06_RS02705	COG1605	Chorismate mutase
LXN06_RS02710	COG0028	Belongs to the TPP enzyme family
LXN06_RS02715	COG3397	chitin binding
LXN06_RS02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS02730	COG1914	H( )-stimulated, divalent metal cation uptake system
LXN06_RS02735	COG2261	transglycosylase associated protein
LXN06_RS02740	COG1027	Aspartate ammonia-lyase
LXN06_RS02745	COG1819	glycosyl
LXN06_RS02750	COG4876	unkown
LXN06_RS02755	COG2217	Heavy metal translocating P-type atpase
LXN06_RS02765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS02765	COG2207	Transcriptional regulator
LXN06_RS02790	COG0662	Cupin 2, conserved barrel domain protein
LXN06_RS02800	COG0628	permease
LXN06_RS02805	COG1301	dicarboxylic acid transport
LXN06_RS02810	COG1131	(ABC) transporter
LXN06_RS02815	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXN06_RS02825	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS02840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS02845	COG1181	Belongs to the D-alanine--D-alanine ligase family
LXN06_RS02850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LXN06_RS02860	COG0513	Belongs to the DEAD box helicase family
LXN06_RS02865	COG3402	PFAM membrane-flanked domain
LXN06_RS02870	COG3428	Bacterial PH domain
LXN06_RS02875	COG0705	Rhomboid family
LXN06_RS02880	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LXN06_RS02885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXN06_RS02890	COG0864	Transcriptional regulator
LXN06_RS02895	COG2337	Toxic component of a toxin-antitoxin (TA) module
LXN06_RS02900	COG1366	Belongs to the anti-sigma-factor antagonist family
LXN06_RS02905	COG1366	Belongs to the anti-sigma-factor antagonist family
LXN06_RS02910	COG2172	sigma factor antagonist activity
LXN06_RS02915	COG2208	phosphoserine phosphatase activity
LXN06_RS02930	COG1191	sigma factor activity
LXN06_RS02935	COG2208	phosphoserine phosphatase activity
LXN06_RS02940	COG2183	response to ionizing radiation
LXN06_RS02945	COG1309	transcriptional regulator
LXN06_RS02950	COG1033	growth of symbiont in host cell
LXN06_RS02950	COG2409	Drug exporters of the RND superfamily
LXN06_RS02960	COG3091	SprT-like family
LXN06_RS03000	COG0726	polysaccharide deacetylase
LXN06_RS03005	COG3239	Fatty acid desaturase
LXN06_RS03010	COG1278	Cold shock
LXN06_RS03015	COG1329	Transcriptional regulator
LXN06_RS03030	COG1846	Transcriptional regulator
LXN06_RS03035	COG0456	acetyltransferase
LXN06_RS03040	COG2808	Putative FMN-binding domain
LXN06_RS03050	COG1733	regulation of RNA biosynthetic process
LXN06_RS03055	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS03080	COG3545	Serine hydrolase
LXN06_RS03085	COG1733	regulation of RNA biosynthetic process
LXN06_RS03090	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LXN06_RS03095	COG1113	amino acid transport
LXN06_RS03110	COG1595	DNA-templated transcription, initiation
LXN06_RS03120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LXN06_RS03120	COG2755	lipolytic protein G-D-S-L family
LXN06_RS03125	COG2814	Major facilitator Superfamily
LXN06_RS03130	COG1979	alcohol dehydrogenase
LXN06_RS03135	COG0745	RESPONSE REGULATOR receiver
LXN06_RS03135	COG2972	Histidine kinase
LXN06_RS03145	COG3279	Response regulator of the LytR AlgR family
LXN06_RS03155	COG3764	Sortase (surface protein transpeptidase)
LXN06_RS03160	COG2814	Major facilitator Superfamily
LXN06_RS03200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LXN06_RS03205	COG0802	atpase or kinase
LXN06_RS03210	COG1214	PFAM Peptidase M22, glycoprotease
LXN06_RS03215	COG0456	acetyltransferase
LXN06_RS03220	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LXN06_RS03225	COG0488	(ABC) transporter
LXN06_RS03230	COG0315	cyclic pyranopterin monophosphate synthase activity
LXN06_RS03235	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LXN06_RS03240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LXN06_RS03245	COG0805	protein transport
LXN06_RS03255	COG1266	CAAX protease self-immunity
LXN06_RS03260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LXN06_RS03265	COG0459	protein refolding
LXN06_RS03275	COG2720	vancomycin resistance protein
LXN06_RS03295	COG2135	peptidase activity
LXN06_RS03305	COG1309	transcriptional regulator
LXN06_RS03310	COG0574	Belongs to the PEP-utilizing enzyme family
LXN06_RS03310	COG3848	Pyruvate phosphate dikinase
LXN06_RS03320	COG3189	MarR family transcriptional regulator
LXN06_RS03325	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
LXN06_RS03330	COG2272	Belongs to the type-B carboxylesterase lipase family
LXN06_RS03335	COG2814	Major facilitator Superfamily
LXN06_RS03340	COG1842	Phage shock protein A
LXN06_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXN06_RS03350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LXN06_RS03355	COG4260	virion core protein, lumpy skin disease virus
LXN06_RS03365	COG1378	Sugar-specific transcriptional regulator TrmB
LXN06_RS03370	COG1280	lysine exporter protein (LysE YggA)
LXN06_RS03375	COG3339	Conserved Protein
LXN06_RS03380	COG0772	Belongs to the SEDS family
LXN06_RS03385	COG0772	Belongs to the SEDS family
LXN06_RS03405	COG0726	polysaccharide deacetylase
LXN06_RS03415	COG1609	Transcriptional regulator
LXN06_RS03420	COG0366	Alpha amylase catalytic
LXN06_RS03425	COG2182	Extracellular solute-binding protein
LXN06_RS03430	COG1175	transmembrane transport
LXN06_RS03435	COG3833	ABC-type maltose transport systems, permease component
LXN06_RS03440	COG5521	maltodextrose utilization protein MalA
LXN06_RS03445	COG1554	hydrolase, family 65, central catalytic
LXN06_RS03450	COG0366	Alpha amylase catalytic
LXN06_RS03455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXN06_RS03460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXN06_RS03465	COG1846	Transcriptional regulator
LXN06_RS03480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LXN06_RS03485	COG0823	Involved in the tonB-independent uptake of proteins
LXN06_RS03510	COG0702	epimerase
LXN06_RS03520	COG2132	Multicopper oxidase
LXN06_RS03540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LXN06_RS03545	COG0714	Associated with various cellular activities
LXN06_RS03550	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LXN06_RS03555	COG1305	Transglutaminase-like
LXN06_RS03560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LXN06_RS03560	COG0519	Catalyzes the synthesis of GMP from XMP
LXN06_RS03565	COG2252	PERMEase
LXN06_RS03580	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LXN06_RS03590	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LXN06_RS03595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LXN06_RS03600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LXN06_RS03605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LXN06_RS03610	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXN06_RS03615	COG0047	phosphoribosylformylglycinamidine synthase activity
LXN06_RS03620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LXN06_RS03625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LXN06_RS03630	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LXN06_RS03635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LXN06_RS03640	COG0138	bifunctional purine biosynthesis protein purh
LXN06_RS03645	COG0151	Belongs to the GarS family
LXN06_RS03650	COG1309	transcriptional regulator
LXN06_RS03655	COG2124	cytochrome p450
LXN06_RS03685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LXN06_RS03690	COG1470	cell adhesion involved in biofilm formation
LXN06_RS03695	COG4496	protein, YerC YecD
LXN06_RS03700	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LXN06_RS03705	COG0210	DNA helicase
LXN06_RS03710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LXN06_RS03715	COG4851	CamS sex pheromone cAM373 precursor
LXN06_RS03720	COG2188	Transcriptional regulator
LXN06_RS03740	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LXN06_RS03745	COG0626	cystathionine gamma-synthase activity
LXN06_RS03750	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LXN06_RS03755	COG3457	Alanine racemase
LXN06_RS03760	COG0363	glucosamine-6-phosphate deaminase activity
LXN06_RS03765	COG1285	pathogenesis
LXN06_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS03775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXN06_RS03780	COG0154	amidase activity
LXN06_RS03785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LXN06_RS03790	COG4124	Belongs to the glycosyl hydrolase 26 family
LXN06_RS03795	COG1309	transcriptional regulator
LXN06_RS03800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LXN06_RS03810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS03815	COG1957	nucleoside hydrolase
LXN06_RS03820	COG1597	lipid kinase activity
LXN06_RS03825	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LXN06_RS03835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS03835	COG1263	PTS System
LXN06_RS03835	COG2190	(PTS) system
LXN06_RS03840	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS03845	COG3711	transcriptional antiterminator
LXN06_RS03850	COG0457	Tetratricopeptide repeat
LXN06_RS03860	COG2226	methyltransferase
LXN06_RS03865	COG0217	transcriptional regulatory protein
LXN06_RS03880	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS03885	COG0840	transmembrane signaling receptor activity
LXN06_RS03890	COG0109	protoheme IX farnesyltransferase activity
LXN06_RS03905	COG0471	metal ion transport
LXN06_RS03910	COG0488	(ABC) transporter
LXN06_RS03915	COG0583	DNA-binding transcription factor activity
LXN06_RS03925	COG1469	GTP cyclohydrolase I activity
LXN06_RS03940	COG0523	cobalamin synthesis protein
LXN06_RS03945	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LXN06_RS03950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXN06_RS03955	COG0156	8-amino-7-oxononanoate synthase activity
LXN06_RS03960	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LXN06_RS03965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LXN06_RS03970	COG2124	cytochrome p450
LXN06_RS03980	COG0789	Transcriptional regulator
LXN06_RS03985	COG2814	Major facilitator Superfamily
LXN06_RS03990	COG0488	(ABC) transporter
LXN06_RS03995	COG0513	Belongs to the DEAD box helicase family
LXN06_RS04000	COG2130	NADP-dependent
LXN06_RS04015	COG0471	metal ion transport
LXN06_RS04025	COG1136	(ABC) transporter
LXN06_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS04055	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LXN06_RS04060	COG3858	chitin binding
LXN06_RS04065	COG5658	integral membrane protein
LXN06_RS04070	COG0640	Transcriptional regulator
LXN06_RS04075	COG1254	Belongs to the acylphosphatase family
LXN06_RS04080	COG2258	MOSC domain
LXN06_RS04095	COG0024	Methionine aminopeptidase
LXN06_RS04100	COG1368	sulfuric ester hydrolase activity
LXN06_RS04110	COG1115	amino acid carrier protein
LXN06_RS04115	COG1263	PTS System
LXN06_RS04115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS04120	COG0366	Alpha amylase catalytic
LXN06_RS04125	COG2188	Transcriptional regulator
LXN06_RS04150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXN06_RS04155	COG1045	serine acetyltransferase
LXN06_RS04160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXN06_RS04170	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS04175	COG0457	Tetratricopeptide repeat
LXN06_RS04175	COG0463	Glycosyl transferase, family 2
LXN06_RS04185	COG0673	inositol 2-dehydrogenase activity
LXN06_RS04200	COG1733	regulation of RNA biosynthetic process
LXN06_RS04205	COG0778	Nitroreductase
LXN06_RS04210	COG0737	Belongs to the 5'-nucleotidase family
LXN06_RS04215	COG0693	protein deglycase activity
LXN06_RS04220	COG4840	Belongs to the UPF0435 family
LXN06_RS04225	COG1115	amino acid carrier protein
LXN06_RS04230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXN06_RS04235	COG4980	gas vesicle protein
LXN06_RS04240	COG1295	ribonuclease BN
LXN06_RS04245	COG0477	Major facilitator Superfamily
LXN06_RS04255	COG0387	Pfam Sodium calcium exchanger
LXN06_RS04265	COG0535	radical SAM domain protein
LXN06_RS04275	COG0726	polysaccharide deacetylase
LXN06_RS04280	COG0371	Dehydrogenase
LXN06_RS04290	COG0598	Magnesium transport protein CorA
LXN06_RS04295	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LXN06_RS04300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LXN06_RS04305	COG4637	Psort location Cytoplasmic, score
LXN06_RS04330	COG1819	glycosyl
LXN06_RS04340	COG0477	Major facilitator Superfamily
LXN06_RS04350	COG1263	PTS System
LXN06_RS04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS04355	COG3711	transcriptional antiterminator
LXN06_RS04360	COG0288	reversible hydration of carbon dioxide
LXN06_RS04365	COG3002	Belongs to the UPF0753 family
LXN06_RS04370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXN06_RS04375	COG5609	conserved protein (DUF2294)
LXN06_RS04385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXN06_RS04390	COG0022	dehydrogenase e1 component
LXN06_RS04395	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXN06_RS04400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXN06_RS04405	COG3284	Transcriptional regulator
LXN06_RS04410	COG1742	UPF0060 membrane protein
LXN06_RS04415	COG1486	melibiose metabolic process
LXN06_RS04420	COG1737	Transcriptional regulator
LXN06_RS04425	COG1263	PTS System
LXN06_RS04425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS04440	COG1733	regulation of RNA biosynthetic process
LXN06_RS04445	COG2259	Doxx family
LXN06_RS04450	COG2514	catechol 2,3-dioxygenase activity
LXN06_RS04460	COG3507	Belongs to the glycosyl hydrolase 43 family
LXN06_RS04470	COG1653	transport
LXN06_RS04475	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS04480	COG1051	belongs to the nudix hydrolase family
LXN06_RS04490	COG0392	lysyltransferase activity
LXN06_RS04490	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LXN06_RS04495	COG0384	phenazine biosynthesis protein PhzF
LXN06_RS04500	COG0778	Nitroreductase
LXN06_RS04520	COG1090	epimerase
LXN06_RS04525	COG2137	regulation of response to DNA damage stimulus
LXN06_RS04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXN06_RS04555	COG0463	Glycosyl transferase, family 2
LXN06_RS04565	COG4485	Bacterial membrane protein, YfhO
LXN06_RS04570	COG1988	membrane-bound metal-dependent
LXN06_RS04575	COG1194	a g-specific adenine glycosylase
LXN06_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS04600	COG3557	Belongs to the UPF0374 family
LXN06_RS04605	COG1132	(ABC) transporter
LXN06_RS04610	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS04615	COG4608	Belongs to the ABC transporter superfamily
LXN06_RS04620	COG0747	negative chemotaxis
LXN06_RS04625	COG0601	transmembrane transport
LXN06_RS04630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS04635	COG4129	membrane
LXN06_RS04640	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LXN06_RS04645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LXN06_RS04650	COG0735	belongs to the Fur family
LXN06_RS04760	COG4974	Belongs to the 'phage' integrase family
LXN06_RS04770	COG0457	Tetratricopeptide repeat
LXN06_RS04825	COG5444	nuclease activity
LXN06_RS04850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LXN06_RS04860	COG0710	3-dehydroquinate dehydratase activity
LXN06_RS04865	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LXN06_RS04870	COG1116	anion transmembrane transporter activity
LXN06_RS04875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXN06_RS04880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXN06_RS04885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXN06_RS04895	COG1476	TRANSCRIPTIONal
LXN06_RS04905	COG1131	(ABC) transporter
LXN06_RS04925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LXN06_RS04935	COG3382	B3 4 domain protein
LXN06_RS04940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LXN06_RS04950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LXN06_RS04955	COG0789	Transcriptional regulator
LXN06_RS04960	COG1664	Polymer-forming cytoskeletal
LXN06_RS04965	COG1664	Polymer-forming cytoskeletal
LXN06_RS04970	COG2766	serine protein kinase
LXN06_RS04975	COG2718	Belongs to the UPF0229 family
LXN06_RS04980	COG1566	PFAM secretion protein HlyD family protein
LXN06_RS04985	COG2814	Major facilitator Superfamily
LXN06_RS04990	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS05005	COG1725	Transcriptional regulator
LXN06_RS05010	COG1131	(ABC) transporter
LXN06_RS05015	COG1131	(ABC) transporter
LXN06_RS05020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXN06_RS05025	COG1278	Cold shock
LXN06_RS05030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXN06_RS05035	COG2011	ABC-type metal ion transport system permease component
LXN06_RS05040	COG1464	Belongs to the NlpA lipoprotein family
LXN06_RS05045	COG1823	symporter activity
LXN06_RS05070	COG5577	PFAM Coat F domain
LXN06_RS05080	COG5002	protein histidine kinase activity
LXN06_RS05085	COG0737	Belongs to the 5'-nucleotidase family
LXN06_RS05085	COG1525	nuclease
LXN06_RS05085	COG4085	toxin activity
LXN06_RS05090	COG3764	Sortase (surface protein transpeptidase)
LXN06_RS05095	COG0564	pseudouridine synthase activity
LXN06_RS05105	COG0517	IMP dehydrogenase activity
LXN06_RS05110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LXN06_RS05115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXN06_RS05115	COG3153	acetyltransferase
LXN06_RS05120	COG0488	(ABC) transporter
LXN06_RS05125	COG2116	formate transmembrane transporter activity
LXN06_RS05135	COG0679	Auxin Efflux Carrier
LXN06_RS05140	COG0604	alcohol dehydrogenase
LXN06_RS05145	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LXN06_RS05150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LXN06_RS05155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LXN06_RS05160	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LXN06_RS05165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LXN06_RS05180	COG4585	Histidine kinase
LXN06_RS05180	COG2203	Gaf domain
LXN06_RS05185	COG2197	response regulator
LXN06_RS05190	COG0431	NADPH-dependent FMN reductase
LXN06_RS05205	COG1959	2 iron, 2 sulfur cluster binding
LXN06_RS05210	COG1017	nitric oxide dioxygenase activity
LXN06_RS05210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LXN06_RS05215	COG2719	SpoVR family
LXN06_RS05220	COG1388	LysM domain
LXN06_RS05220	COG0791	NLP P60 protein
LXN06_RS05225	COG0583	DNA-binding transcription factor activity
LXN06_RS05230	COG0372	Belongs to the citrate synthase family
LXN06_RS05235	COG2133	pyrroloquinoline quinone binding
LXN06_RS05240	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS05245	COG0733	neurotransmitter:sodium symporter activity
LXN06_RS05255	COG2207	Transcriptional regulator
LXN06_RS05255	COG3708	Transcriptional regulator
LXN06_RS05260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXN06_RS05280	COG1595	DNA-templated transcription, initiation
LXN06_RS05285	COG0662	Cupin 2, conserved barrel domain protein
LXN06_RS05290	COG0667	Aldo Keto reductase
LXN06_RS05295	COG0204	Acyl-transferase
LXN06_RS05300	COG3152	Membrane
LXN06_RS05310	COG1309	transcriptional regulator
LXN06_RS05315	COG1253	flavin adenine dinucleotide binding
LXN06_RS05320	COG0789	Transcriptional regulator
LXN06_RS05325	COG1253	flavin adenine dinucleotide binding
LXN06_RS05345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXN06_RS05350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LXN06_RS05355	COG0584	glycerophosphoryl diester phosphodiesterase
LXN06_RS05365	COG0668	transmembrane transport
LXN06_RS05370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LXN06_RS05380	COG0726	polysaccharide deacetylase
LXN06_RS05390	COG1757	Na H antiporter
LXN06_RS05395	COG2017	converts alpha-aldose to the beta-anomer
LXN06_RS05420	COG0589	response to stress
LXN06_RS05425	COG1132	(ABC) transporter
LXN06_RS05430	COG1132	(ABC) transporter
LXN06_RS05435	COG0702	epimerase
LXN06_RS05455	COG3842	ATPase activity
LXN06_RS05460	COG2508	Transcriptional regulator
LXN06_RS05470	COG0189	ligase activity
LXN06_RS05475	COG0189	ligase activity
LXN06_RS05480	COG4399	Belongs to the UPF0754 family
LXN06_RS05485	COG3679	Belongs to the UPF0342 family
LXN06_RS05490	COG0561	phosphatase activity
LXN06_RS05495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXN06_RS05500	COG1024	Enoyl-CoA hydratase
LXN06_RS05505	COG0457	Tetratricopeptide repeat
LXN06_RS05525	COG4152	abc transporter atp-binding protein
LXN06_RS05530	COG1668	transmembrane transport
LXN06_RS05535	COG0420	3'-5' exonuclease activity
LXN06_RS05540	COG4717	serine-type aminopeptidase activity
LXN06_RS05545	COG3481	metal-dependent phosphohydrolase, HD sub domain
LXN06_RS05555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LXN06_RS05585	COG1846	Transcriptional regulator
LXN06_RS05590	COG4980	gas vesicle protein
LXN06_RS05605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LXN06_RS05610	COG0537	adenosine 5'-monophosphoramidase activity
LXN06_RS05615	COG1131	(ABC) transporter
LXN06_RS05620	COG4473	ABC transporter
LXN06_RS05630	COG1473	amidohydrolase
LXN06_RS05635	COG3069	C4-dicarboxylate transmembrane transporter activity
LXN06_RS05640	COG2329	Antibiotic biosynthesis monooxygenase
LXN06_RS05645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXN06_RS05650	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LXN06_RS05655	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXN06_RS05660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LXN06_RS05665	COG1309	transcriptional regulator
LXN06_RS05670	COG1511	domain protein
LXN06_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXN06_RS05680	COG1363	Peptidase, m42
LXN06_RS05690	COG1301	dicarboxylic acid transport
LXN06_RS05700	COG1234	tRNA 3'-trailer cleavage
LXN06_RS05705	COG0095	Lipoate-protein ligase
LXN06_RS05710	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS05720	COG1396	sequence-specific DNA binding
LXN06_RS05735	COG0501	Belongs to the peptidase M48B family
LXN06_RS05745	COG0697	spore germination
LXN06_RS05750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LXN06_RS05755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS05760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS05765	COG0406	alpha-ribazole phosphatase activity
LXN06_RS05770	COG0840	transmembrane signaling receptor activity
LXN06_RS05775	COG0723	plastoquinol--plastocyanin reductase activity
LXN06_RS05775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXN06_RS05780	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS05790	COG4903	ComK protein
LXN06_RS05800	COG0398	Pfam SNARE associated Golgi protein
LXN06_RS05805	COG0681	Belongs to the peptidase S26 family
LXN06_RS05810	COG1404	Belongs to the peptidase S8 family
LXN06_RS05820	COG2508	Transcriptional regulator
LXN06_RS05830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXN06_RS05835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXN06_RS05840	COG3257	ureidoglycine aminohydrolase activity
LXN06_RS05845	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LXN06_RS05850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LXN06_RS05855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXN06_RS05860	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXN06_RS05870	COG0549	Belongs to the carbamate kinase family
LXN06_RS05885	COG0457	Tetratricopeptide repeat
LXN06_RS05905	COG3180	Ammonia monooxygenase
LXN06_RS05920	COG3546	catalase activity
LXN06_RS05925	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS05930	COG0477	Major facilitator Superfamily
LXN06_RS05930	COG2814	Major facilitator Superfamily
LXN06_RS05935	COG4533	DNA binding
LXN06_RS05945	COG5002	protein histidine kinase activity
LXN06_RS05950	COG0745	RESPONSE REGULATOR receiver
LXN06_RS05955	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LXN06_RS05960	COG0725	ABC transporter, periplasmic molybdate-binding protein
LXN06_RS05965	COG4149	molybdate abc transporter
LXN06_RS05970	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LXN06_RS05975	COG1074	ATP-dependent DNA helicase activity
LXN06_RS05980	COG0420	3'-5' exonuclease activity
LXN06_RS05985	COG0419	ATPase involved in DNA repair
LXN06_RS06030	COG5337	Spore coat protein CotH
LXN06_RS06040	COG0179	Fumarylacetoacetate (FAA) hydrolase
LXN06_RS06060	COG0367	asparagine synthase
LXN06_RS06065	COG0004	ammonium transporteR
LXN06_RS06070	COG0347	Belongs to the P(II) protein family
LXN06_RS06075	COG0534	Mate efflux family protein
LXN06_RS06080	COG1917	Cupin 2, conserved barrel domain protein
LXN06_RS06080	COG2207	Transcriptional regulator
LXN06_RS06090	COG1609	Transcriptional regulator
LXN06_RS06095	COG0673	inositol 2-dehydrogenase activity
LXN06_RS06110	COG0697	spore germination
LXN06_RS06115	COG1279	arginine transmembrane transporter activity
LXN06_RS06120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXN06_RS06130	COG0076	glutamate decarboxylase activity
LXN06_RS06155	COG2153	protein acetylation
LXN06_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS06165	COG2378	regulation of single-species biofilm formation
LXN06_RS06170	COG0646	methionine synthase
LXN06_RS06170	COG1410	methionine synthase
LXN06_RS06175	COG0646	methionine synthase
LXN06_RS06175	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LXN06_RS06180	COG1666	GTP binding
LXN06_RS06185	COG2996	Protein conserved in bacteria
LXN06_RS06200	COG1307	EDD domain protein, DegV family
LXN06_RS06205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS06215	COG0516	GMP reductase activity
LXN06_RS06230	COG0561	phosphatase activity
LXN06_RS06235	COG1073	alpha beta
LXN06_RS06240	COG2151	metal-sulfur cluster biosynthetic enzyme
LXN06_RS06245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LXN06_RS06250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LXN06_RS06255	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LXN06_RS06260	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LXN06_RS06265	COG0505	Belongs to the CarA family
LXN06_RS06270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXN06_RS06275	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LXN06_RS06280	COG1968	undecaprenyl-diphosphatase activity
LXN06_RS06295	COG2267	carboxylic ester hydrolase activity
LXN06_RS06305	COG1744	ABC transporter substrate-binding protein PnrA-like
LXN06_RS06320	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXN06_RS06325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LXN06_RS06330	COG5504	Zn-dependent protease
LXN06_RS06335	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS06340	COG4608	Belongs to the ABC transporter superfamily
LXN06_RS06350	COG0601	transmembrane transport
LXN06_RS06355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS06365	COG0180	Tryptophanyl-tRNA synthetase
LXN06_RS06370	COG4166	transmembrane transport
LXN06_RS06375	COG0601	transmembrane transport
LXN06_RS06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS06385	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS06390	COG4608	Belongs to the ABC transporter superfamily
LXN06_RS06395	COG0456	acetyltransferase
LXN06_RS06400	COG1393	Belongs to the ArsC family
LXN06_RS06405	COG0861	Integral membrane protein TerC family
LXN06_RS06415	COG4862	establishment of competence for transformation
LXN06_RS06445	COG4565	transcriptional regulatory protein
LXN06_RS06450	COG3290	protein histidine kinase activity
LXN06_RS06455	COG4469	Competence protein
LXN06_RS06460	COG1164	Oligoendopeptidase f
LXN06_RS06470	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LXN06_RS06475	COG2346	COG2346, Truncated hemoglobins
LXN06_RS06480	COG0741	lytic transglycosylase activity
LXN06_RS06485	COG4116	CYTH
LXN06_RS06495	COG2357	RelA SpoT domain protein
LXN06_RS06500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXN06_RS06505	COG0564	pseudouridine synthase activity
LXN06_RS06510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LXN06_RS06515	COG0475	glutathione-regulated potassium exporter activity
LXN06_RS06515	COG0569	domain protein
LXN06_RS06520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXN06_RS06525	COG0352	thiamine-phosphate diphosphorylase activity
LXN06_RS06535	COG2104	thiamine diphosphate biosynthetic process
LXN06_RS06540	COG2022	thiamine diphosphate biosynthetic process
LXN06_RS06545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXN06_RS06550	COG0351	phosphomethylpyrimidine kinase
LXN06_RS06555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LXN06_RS06610	COG0210	DNA helicase
LXN06_RS06620	COG0586	Pfam SNARE associated Golgi protein
LXN06_RS06635	COG2246	polysaccharide biosynthetic process
LXN06_RS06640	COG2153	protein acetylation
LXN06_RS06645	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LXN06_RS06650	COG2382	esterase
LXN06_RS06670	COG0626	cystathionine gamma-synthase activity
LXN06_RS06675	COG0626	cystathionine gamma-synthase activity
LXN06_RS06680	COG5505	Protein of unknown function (DUF819)
LXN06_RS06695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXN06_RS06710	COG3507	Belongs to the glycosyl hydrolase 43 family
LXN06_RS06730	COG0110	maltose O-acetyltransferase activity
LXN06_RS06740	COG0583	DNA-binding transcription factor activity
LXN06_RS06745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXN06_RS06750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LXN06_RS06755	COG0583	DNA-binding transcription factor activity
LXN06_RS06760	COG0697	spore germination
LXN06_RS06765	COG0346	lactoylglutathione lyase activity
LXN06_RS06775	COG1388	LysM domain
LXN06_RS06775	COG3584	3D domain protein
LXN06_RS06780	COG2814	Major facilitator Superfamily
LXN06_RS06785	COG1309	transcriptional regulator
LXN06_RS06805	COG4195	phage-related replication protein
LXN06_RS06810	COG2856	Zn peptidase
LXN06_RS06815	COG1396	sequence-specific DNA binding
LXN06_RS06830	COG1522	sequence-specific DNA binding
LXN06_RS06835	COG1484	DNA-dependent DNA replication
LXN06_RS06855	COG1595	DNA-templated transcription, initiation
LXN06_RS06860	COG3728	DNA packaging
LXN06_RS06860	COG5484	DNA packaging
LXN06_RS06865	COG1783	phage Terminase large subunit
LXN06_RS06870	COG5518	Phage portal protein
LXN06_RS06875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LXN06_RS06880	COG4653	Phage capsid family
LXN06_RS06930	COG5280	Phage tail tape measure protein TP901
LXN06_RS06930	COG3953	SLT domain
LXN06_RS06935	COG1652	LysM domain
LXN06_RS06940	COG4193	domain, Protein
LXN06_RS06950	COG3628	GPW Gp25 family protein
LXN06_RS06955	COG3299	homolog of phage Mu protein gp47
LXN06_RS06960	COG3778	Protein conserved in bacteria
LXN06_RS06995	COG1802	Transcriptional regulator
LXN06_RS07000	COG1063	alcohol dehydrogenase
LXN06_RS07005	COG1312	Catalyzes the dehydration of D-mannonate
LXN06_RS07010	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS07015	COG1063	alcohol dehydrogenase
LXN06_RS07020	COG2271	Major facilitator Superfamily
LXN06_RS07040	COG0306	phosphate transporter
LXN06_RS07045	COG1392	Phosphate transport regulator
LXN06_RS07050	COG0405	Gamma-glutamyltransferase
LXN06_RS07055	COG5578	integral membrane protein
LXN06_RS07060	COG2972	Histidine kinase
LXN06_RS07065	COG4753	response regulator
LXN06_RS07065	COG2207	Transcriptional regulator
LXN06_RS07070	COG1653	transport
LXN06_RS07075	COG1175	transmembrane transport
LXN06_RS07080	COG0395	ABC-type sugar transport system, permease component
LXN06_RS07085	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LXN06_RS07090	COG2207	Transcriptional regulator
LXN06_RS07095	COG2755	lipolytic protein G-D-S-L family
LXN06_RS07105	COG5578	integral membrane protein
LXN06_RS07110	COG3401	FG-GAP repeat protein
LXN06_RS07115	COG2755	lipolytic protein G-D-S-L family
LXN06_RS07120	COG3401	FG-GAP repeat protein
LXN06_RS07125	COG0667	Aldo Keto reductase
LXN06_RS07130	COG2755	lipolytic protein G-D-S-L family
LXN06_RS07135	COG1874	Beta-galactosidase
LXN06_RS07145	COG1653	transport
LXN06_RS07150	COG4209	transmembrane transport
LXN06_RS07155	COG0395	ABC-type sugar transport system, permease component
LXN06_RS07160	COG0531	amino acid
LXN06_RS07165	COG0346	lactoylglutathione lyase activity
LXN06_RS07175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXN06_RS07180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LXN06_RS07185	COG2362	D-Aminopeptidase
LXN06_RS07190	COG0601	transmembrane transport
LXN06_RS07195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS07200	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS07205	COG4166	transmembrane transport
LXN06_RS07210	COG1619	proteins homologs of microcin C7 resistance protein MccF
LXN06_RS07215	COG4948	Mandelate Racemase Muconate Lactonizing
LXN06_RS07220	COG0791	NLP P60 protein
LXN06_RS07225	COG4608	Belongs to the ABC transporter superfamily
LXN06_RS07230	COG1834	amidinotransferase
LXN06_RS07235	COG1607	acyl-coa hydrolase
LXN06_RS07240	COG2323	membrane
LXN06_RS07245	COG3866	Pectate lyase
LXN06_RS07265	COG2318	DinB family
LXN06_RS07270	COG2076	Multidrug Resistance protein
LXN06_RS07275	COG2076	Multidrug Resistance protein
LXN06_RS07280	COG0788	formyltetrahydrofolate deformylase activity
LXN06_RS07285	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXN06_RS07290	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LXN06_RS07295	COG1764	response to oxidative stress
LXN06_RS07300	COG1846	Transcriptional regulator
LXN06_RS07305	COG1764	response to oxidative stress
LXN06_RS07315	COG0590	tRNA wobble adenosine to inosine editing
LXN06_RS07320	COG0406	alpha-ribazole phosphatase activity
LXN06_RS07335	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LXN06_RS07340	COG1404	Belongs to the peptidase S8 family
LXN06_RS07350	COG2239	Acts as a magnesium transporter
LXN06_RS07360	COG0789	Transcriptional regulator
LXN06_RS07375	COG1846	Transcriptional regulator
LXN06_RS07380	COG1793	dna ligase
LXN06_RS07380	COG3285	dna ligase
LXN06_RS07385	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LXN06_RS07390	COG5001	Diguanylate cyclase
LXN06_RS07390	COG3300	MHYT domain
LXN06_RS07395	COG0586	Pfam SNARE associated Golgi protein
LXN06_RS07405	COG1191	sigma factor activity
LXN06_RS07425	COG0501	Belongs to the peptidase M48B family
LXN06_RS07430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXN06_RS07435	COG0768	penicillin binding
LXN06_RS07450	COG3594	Acyltransferase
LXN06_RS07455	COG5002	protein histidine kinase activity
LXN06_RS07460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXN06_RS07470	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LXN06_RS07475	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LXN06_RS07480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LXN06_RS07485	COG0436	Aminotransferase
LXN06_RS07490	COG1850	ribulose-bisphosphate carboxylase activity
LXN06_RS07495	COG0235	Class ii aldolase
LXN06_RS07495	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LXN06_RS07500	COG0235	Class ii aldolase
LXN06_RS07500	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LXN06_RS07505	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LXN06_RS07510	COG0346	lactoylglutathione lyase activity
LXN06_RS07515	COG3339	Conserved Protein
LXN06_RS07525	COG3852	Histidine kinase
LXN06_RS07530	COG1846	Transcriptional regulator
LXN06_RS07535	COG1360	Flagellar Motor Protein
LXN06_RS07540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LXN06_RS07545	COG0542	response to heat
LXN06_RS07550	COG3949	Membrane
LXN06_RS07555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LXN06_RS07560	COG0720	synthase
LXN06_RS07565	COG0602	queuosine metabolic process
LXN06_RS07570	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LXN06_RS07575	COG0457	Tetratricopeptide repeat
LXN06_RS07585	COG3739	integral membrane protein
LXN06_RS07590	COG3655	Transcriptional regulator
LXN06_RS07635	COG4873	Protein conserved in bacteria
LXN06_RS07645	COG3773	Cell wall hydrolase
LXN06_RS07650	COG2244	polysaccharide biosynthetic process
LXN06_RS07655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS07660	COG2217	Heavy metal translocating P-type atpase
LXN06_RS07665	COG0006	proline dipeptidase activity
LXN06_RS07680	COG3711	transcriptional antiterminator
LXN06_RS07685	COG2190	(PTS) system
LXN06_RS07685	COG1263	PTS System
LXN06_RS07685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS07690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS07695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LXN06_RS07705	COG1533	DNA photolyase activity
LXN06_RS07710	COG0456	acetyltransferase
LXN06_RS07715	COG0840	transmembrane signaling receptor activity
LXN06_RS07720	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS07725	COG2084	Dehydrogenase
LXN06_RS07730	COG2340	Cysteine-rich secretory protein family
LXN06_RS07735	COG0768	penicillin binding
LXN06_RS07740	COG4191	Histidine kinase
LXN06_RS07745	COG0436	Aminotransferase
LXN06_RS07755	COG1714	RDD family
LXN06_RS07765	COG0835	chemotaxis
LXN06_RS07765	COG0784	Response regulator, receiver
LXN06_RS07775	COG2814	Major facilitator Superfamily
LXN06_RS07780	COG1376	ErfK ybiS ycfS ynhG family protein
LXN06_RS07785	COG1408	metallophosphoesterase
LXN06_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS07795	COG2200	EAL domain
LXN06_RS07810	COG4703	Protein of unknown function (DUF1797)
LXN06_RS07815	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LXN06_RS07825	COG0517	IMP dehydrogenase activity
LXN06_RS07830	COG0583	DNA-binding transcription factor activity
LXN06_RS07835	COG0716	FMN binding
LXN06_RS07845	COG0716	FMN binding
LXN06_RS07850	COG2171	N-acyltransferase activity
LXN06_RS07855	COG1473	amidohydrolase
LXN06_RS07865	COG0450	alkyl hydroperoxide reductase
LXN06_RS07870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS07885	COG0746	molybdenum cofactor guanylyltransferase activity
LXN06_RS07890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LXN06_RS07895	COG0303	'Molybdopterin
LXN06_RS07900	COG1763	Mo-molybdopterin cofactor biosynthetic process
LXN06_RS07905	COG0314	molybdopterin synthase activity
LXN06_RS07910	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LXN06_RS07920	COG1132	(ABC) transporter
LXN06_RS07925	COG1132	(ABC) transporter
LXN06_RS07935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LXN06_RS07940	COG1136	(ABC) transporter
LXN06_RS07945	COG0577	efflux transmembrane transporter activity
LXN06_RS07960	COG1349	DNA-binding transcription factor activity
LXN06_RS07965	COG1105	Belongs to the carbohydrate kinase PfkB family
LXN06_RS07970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS07970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS07970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS07990	COG0488	(ABC) transporter
LXN06_RS08000	COG2309	aminopeptidase activity
LXN06_RS08010	COG1077	Cell shape determining protein MreB Mrl
LXN06_RS08015	COG2002	toxin-antitoxin pair type II binding
LXN06_RS08020	COG3852	Histidine kinase
LXN06_RS08025	COG0569	domain protein
LXN06_RS08030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LXN06_RS08035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LXN06_RS08040	COG5503	Protein of unknown function (DUF1447)
LXN06_RS08045	COG0561	phosphatase activity
LXN06_RS08050	COG0242	peptide deformylase activity
LXN06_RS08060	COG0497	DNA recombination
LXN06_RS08065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXN06_RS08070	COG0022	dehydrogenase e1 component
LXN06_RS08075	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXN06_RS08080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXN06_RS08085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS08095	COG1982	Orn Lys Arg decarboxylase major
LXN06_RS08100	COG4476	Belongs to the UPF0223 family
LXN06_RS08105	COG4493	Belongs to the UPF0637 family
LXN06_RS08115	COG0483	inositol monophosphate 1-phosphatase activity
LXN06_RS08135	COG1595	DNA-templated transcription, initiation
LXN06_RS08150	COG1217	gtp-binding protein TYPA
LXN06_RS08160	COG1846	Transcriptional regulator
LXN06_RS08165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LXN06_RS08170	COG4896	Protein conserved in bacteria
LXN06_RS08180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LXN06_RS08185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXN06_RS08190	COG2066	Belongs to the glutaminase family
LXN06_RS08195	COG4838	Belongs to the UPF0358 family
LXN06_RS08200	COG0772	Belongs to the SEDS family
LXN06_RS08205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LXN06_RS08210	COG1612	heme a metabolic process
LXN06_RS08215	COG0109	protoheme IX farnesyltransferase activity
LXN06_RS08220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXN06_RS08220	COG2010	Cytochrome c
LXN06_RS08225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXN06_RS08230	COG1845	cytochrome c oxidase, subunit III
LXN06_RS08235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXN06_RS08240	COG3336	cytochrome c oxidase
LXN06_RS08250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LXN06_RS08255	COG2340	Cysteine-rich secretory protein family
LXN06_RS08270	COG3679	Belongs to the UPF0342 family
LXN06_RS08275	COG4471	UPF0298 protein
LXN06_RS08280	COG0742	ribosomal rna small subunit methyltransferase
LXN06_RS08285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LXN06_RS08290	COG3314	Sporulation integral membrane protein YlbJ
LXN06_RS08295	COG3480	Lon protease (S16) C-terminal proteolytic domain
LXN06_RS08300	COG1323	Belongs to the UPF0348 family
LXN06_RS08305	COG1399	metal-binding, possibly nucleic acid-binding protein
LXN06_RS08310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LXN06_RS08320	COG0454	-acetyltransferase
LXN06_RS08325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LXN06_RS08330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LXN06_RS08335	COG2001	Belongs to the MraZ family
LXN06_RS08340	COG0275	rRNA processing
LXN06_RS08345	COG4839	cell division protein FtsL
LXN06_RS08350	COG0768	penicillin binding
LXN06_RS08355	COG0768	penicillin binding
LXN06_RS08360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LXN06_RS08365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LXN06_RS08370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXN06_RS08375	COG0772	Belongs to the SEDS family
LXN06_RS08380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXN06_RS08385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LXN06_RS08390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LXN06_RS08395	COG3879	Bacterial protein of unknown function (DUF881)
LXN06_RS08400	COG3879	Bacterial protein of unknown function (DUF881)
LXN06_RS08405	COG3856	small basic protein
LXN06_RS08410	COG0849	cell division
LXN06_RS08415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LXN06_RS08425	COG1404	Belongs to the peptidase S8 family
LXN06_RS08425	COG4412	M6 family metalloprotease domain protein
LXN06_RS08435	COG1191	sigma factor activity
LXN06_RS08440	COG1191	sigma factor activity
LXN06_RS08445	COG1119	ATPase activity
LXN06_RS08450	COG0500	methyltransferase
LXN06_RS08455	COG1873	PFAM PRC-barrel domain
LXN06_RS08460	COG1496	oxidoreductase activity
LXN06_RS08465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LXN06_RS08470	COG1799	cell septum assembly
LXN06_RS08475	COG0762	integral membrane protein
LXN06_RS08480	COG2302	S4 RNA-binding domain
LXN06_RS08485	COG3599	regulation of cell shape
LXN06_RS08490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LXN06_RS08495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXN06_RS08500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LXN06_RS08505	COG0564	pseudouridine synthase activity
LXN06_RS08515	COG2233	PERMEase
LXN06_RS08520	COG0540	Belongs to the ATCase OTCase family
LXN06_RS08525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LXN06_RS08530	COG0505	Belongs to the CarA family
LXN06_RS08535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LXN06_RS08540	COG0543	2 iron, 2 sulfur cluster binding
LXN06_RS08545	COG0167	dihydroorotate dehydrogenase activity
LXN06_RS08550	COG0284	orotidine-5'-phosphate decarboxylase activity
LXN06_RS08555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LXN06_RS08565	COG0175	sulfate reduction
LXN06_RS08570	COG0306	phosphate transporter
LXN06_RS08575	COG2046	Belongs to the sulfate adenylyltransferase family
LXN06_RS08580	COG0529	Catalyzes the synthesis of activated sulfate
LXN06_RS08585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LXN06_RS08590	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LXN06_RS08595	COG1648	precorrin-2 dehydrogenase activity
LXN06_RS08605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LXN06_RS08610	COG1561	YicC-like family, N-terminal region
LXN06_RS08615	COG2052	Domain of unknown function (DUF370)
LXN06_RS08620	COG0194	GDP metabolic process
LXN06_RS08625	COG1758	RNA polymerase activity
LXN06_RS08630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXN06_RS08635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LXN06_RS08640	COG0242	peptide deformylase activity
LXN06_RS08645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LXN06_RS08650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXN06_RS08650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LXN06_RS08655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LXN06_RS08660	COG0631	protein serine/threonine phosphatase activity
LXN06_RS08665	COG2815	serine threonine protein kinase
LXN06_RS08665	COG0515	serine threonine protein kinase
LXN06_RS08670	COG1162	GTPase activity
LXN06_RS08675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LXN06_RS08680	COG1564	THIamine pyrophosphokinase
LXN06_RS08690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LXN06_RS08695	COG1302	Protein conserved in bacteria
LXN06_RS08700	COG1461	Dihydroxyacetone kinase
LXN06_RS08705	COG1760	l-serine dehydratase
LXN06_RS08710	COG1760	l-serine dehydratase
LXN06_RS08715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LXN06_RS08720	COG1349	DNA-binding transcription factor activity
LXN06_RS08725	COG0416	fatty acid biosynthetic process
LXN06_RS08730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LXN06_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS08740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXN06_RS08745	COG0571	ribonuclease III activity
LXN06_RS08750	COG1196	nuclear chromosome segregation
LXN06_RS08755	COG0552	protein localization to endoplasmic reticulum
LXN06_RS08760	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LXN06_RS08765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LXN06_RS08770	COG0228	four-way junction DNA binding
LXN06_RS08775	COG1837	Belongs to the UPF0109 family
LXN06_RS08785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LXN06_RS08790	COG0336	Belongs to the RNA methyltransferase TrmD family
LXN06_RS08795	COG0335	large ribosomal subunit rRNA binding
LXN06_RS08800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LXN06_RS08805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXN06_RS08815	COG2257	FlhB HrpN YscU SpaS Family
LXN06_RS08820	COG0045	succinate-CoA ligase (ADP-forming) activity
LXN06_RS08825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LXN06_RS08830	COG0758	DNA mediated transformation
LXN06_RS08835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LXN06_RS08840	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LXN06_RS08845	COG4974	Belongs to the 'phage' integrase family
LXN06_RS08850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LXN06_RS08855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LXN06_RS08860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LXN06_RS08865	COG1815	bacterial-type flagellum-dependent cell motility
LXN06_RS08870	COG1558	bacterial-type flagellum-dependent cell motility
LXN06_RS08875	COG1677	Flagellar hook-basal body complex protein FliE
LXN06_RS08880	COG1766	The M ring may be actively involved in energy transduction
LXN06_RS08885	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXN06_RS08890	COG1317	bacterial-type flagellum organization
LXN06_RS08895	COG1157	protein secretion by the type III secretion system
LXN06_RS08900	COG2882	bacterial-type flagellum organization
LXN06_RS08910	COG3144	bacterial-type flagellum assembly
LXN06_RS08915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LXN06_RS08920	COG4786	Flagellar basal body rod
LXN06_RS08925	COG1582	Flagellar protein (FlbD)
LXN06_RS08930	COG1580	Controls the rotational direction of flagella during chemotaxis
LXN06_RS08935	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXN06_RS08940	COG1776	CheC inhibitor of MCP methylation
LXN06_RS08940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LXN06_RS08945	COG2201	protein-glutamate methylesterase activity
LXN06_RS08950	COG3190	flagellar
LXN06_RS08955	COG1338	Plays a role in the flagellum-specific transport system
LXN06_RS08960	COG1987	bacterial-type flagellum assembly
LXN06_RS08965	COG1684	flagellar biosynthetic protein fliR
LXN06_RS08970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXN06_RS08975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LXN06_RS08980	COG1419	protein localization to endoplasmic reticulum
LXN06_RS08985	COG0455	bacterial-type flagellum organization
LXN06_RS08990	COG2201	protein-glutamate methylesterase activity
LXN06_RS08995	COG0643	Histidine kinase
LXN06_RS08995	COG2198	Histidine kinase
LXN06_RS09000	COG0835	chemotaxis
LXN06_RS09005	COG1776	CheC inhibitor of MCP methylation
LXN06_RS09010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LXN06_RS09015	COG1191	sigma factor activity
LXN06_RS09025	COG0052	Belongs to the universal ribosomal protein uS2 family
LXN06_RS09030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LXN06_RS09035	COG0528	UMP kinase activity
LXN06_RS09040	COG0233	cytoplasmic translational termination
LXN06_RS09045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LXN06_RS09050	COG4589	Belongs to the CDS family
LXN06_RS09055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LXN06_RS09060	COG0750	zinc metalloprotease
LXN06_RS09065	COG0442	prolyl-tRNA aminoacylation
LXN06_RS09070	COG2176	DNA-directed DNA polymerase activity
LXN06_RS09095	COG0779	Required for maturation of 30S ribosomal subunits
LXN06_RS09100	COG0195	Participates in both transcription termination and antitermination
LXN06_RS09105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LXN06_RS09110	COG1358	cellular component organization or biogenesis
LXN06_RS09115	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LXN06_RS09120	COG1550	Protein conserved in bacteria
LXN06_RS09125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LXN06_RS09130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LXN06_RS09135	COG0196	riboflavin kinase activity
LXN06_RS09140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LXN06_RS09145	COG1185	polyribonucleotide nucleotidyltransferase activity
LXN06_RS09150	COG0726	polysaccharide deacetylase
LXN06_RS09155	COG0612	Peptidase, M16
LXN06_RS09160	COG1873	PFAM PRC-barrel domain
LXN06_RS09165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXN06_RS09170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LXN06_RS09175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LXN06_RS09180	COG0527	aspartate kinase activity
LXN06_RS09190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LXN06_RS09195	COG0740	serine-type endopeptidase activity
LXN06_RS09205	COG1674	ftsk spoiiie
LXN06_RS09205	COG4980	gas vesicle protein
LXN06_RS09210	COG2188	Transcriptional regulator
LXN06_RS09215	COG2814	Major facilitator Superfamily
LXN06_RS09220	COG0612	Peptidase, M16
LXN06_RS09225	COG0612	Peptidase, M16
LXN06_RS09230	COG0300	oxidoreductase activity
LXN06_RS09245	COG1426	Protein conserved in bacteria
LXN06_RS09250	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LXN06_RS09255	COG1058	Belongs to the CinA family
LXN06_RS09255	COG1546	Belongs to the CinA family
LXN06_RS09265	COG1418	mRNA catabolic process
LXN06_RS09270	COG1692	metallophosphoesterase
LXN06_RS09275	COG2359	stage V sporulation protein S
LXN06_RS09285	COG1063	alcohol dehydrogenase
LXN06_RS09295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXN06_RS09300	COG4550	Control of competence regulator ComK, YlbF/YmcA
LXN06_RS09310	COG1595	DNA-templated transcription, initiation
LXN06_RS09315	COG0667	Aldo Keto reductase
LXN06_RS09325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LXN06_RS09330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LXN06_RS09335	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LXN06_RS09345	COG5444	nuclease activity
LXN06_RS09355	COG0523	cobalamin synthesis protein
LXN06_RS09375	COG1231	oxidoreductase activity
LXN06_RS09380	COG3619	membrane
LXN06_RS09385	COG3263	regulation of cellular component size
LXN06_RS09390	COG2814	Major facilitator Superfamily
LXN06_RS09395	COG2267	carboxylic ester hydrolase activity
LXN06_RS09405	COG0393	Putative heavy-metal-binding
LXN06_RS09410	COG0398	Pfam SNARE associated Golgi protein
LXN06_RS09415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LXN06_RS09420	COG1819	glycosyl
LXN06_RS09425	COG0531	amino acid
LXN06_RS09440	COG1388	LysM domain
LXN06_RS09440	COG3858	chitin binding
LXN06_RS09445	COG1309	transcriptional regulator
LXN06_RS09450	COG3631	Ketosteroid isomerase-related protein
LXN06_RS09455	COG0702	epimerase
LXN06_RS09465	COG1764	response to oxidative stress
LXN06_RS09470	COG2076	Multidrug Resistance protein
LXN06_RS09475	COG2076	Multidrug Resistance protein
LXN06_RS09490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LXN06_RS09495	COG1923	regulation of RNA biosynthetic process
LXN06_RS09505	COG1780	Probably involved in ribonucleotide reductase function
LXN06_RS09510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXN06_RS09515	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LXN06_RS09520	COG4112	unkown
LXN06_RS09540	COG1802	Transcriptional regulator
LXN06_RS09545	COG0697	spore germination
LXN06_RS09575	COG1309	transcriptional regulator
LXN06_RS09610	COG4282	regulation of fungal-type cell wall biogenesis
LXN06_RS09620	COG2814	Major facilitator Superfamily
LXN06_RS09625	COG0457	Tetratricopeptide repeat
LXN06_RS09635	COG4413	Urea transporter
LXN06_RS09640	COG0831	urea catabolic process
LXN06_RS09645	COG0832	Belongs to the urease beta subunit family
LXN06_RS09655	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LXN06_RS09660	COG0830	nickel cation binding
LXN06_RS09665	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LXN06_RS09670	COG0829	nickel cation binding
LXN06_RS09680	COG1695	Transcriptional regulator
LXN06_RS09735	COG0464	growth
LXN06_RS09740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LXN06_RS09745	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LXN06_RS09750	COG0789	Transcriptional regulator
LXN06_RS09755	COG0174	glutamine synthetase
LXN06_RS09885	COG1073	alpha beta
LXN06_RS09915	COG1309	transcriptional regulator
LXN06_RS09920	COG2076	Multidrug Resistance protein
LXN06_RS09925	COG2076	Multidrug Resistance protein
LXN06_RS09930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS09945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS09950	COG3546	catalase activity
LXN06_RS09975	COG1846	Transcriptional regulator
LXN06_RS09980	COG0778	Nitroreductase
LXN06_RS09985	COG0346	lactoylglutathione lyase activity
LXN06_RS09990	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXN06_RS09995	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS10020	COG3209	COG3209 Rhs family protein
LXN06_RS10025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LXN06_RS10030	COG1388	LysM domain
LXN06_RS10035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LXN06_RS10040	COG4224	UPF0291 protein
LXN06_RS10045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LXN06_RS10055	COG3763	UPF0154 protein
LXN06_RS10065	COG0785	Cytochrome C biogenesis protein
LXN06_RS10070	COG2201	protein-glutamate methylesterase activity
LXN06_RS10075	COG4846	Membrane protein involved in cytochrome C biogenesis
LXN06_RS10085	COG0071	Belongs to the small heat shock protein (HSP20) family
LXN06_RS10100	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LXN06_RS10105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS10125	COG0824	Thioesterase
LXN06_RS10145	COG4841	protein insertion into membrane
LXN06_RS10150	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LXN06_RS10155	COG1832	CoA-binding protein
LXN06_RS10160	COG0187	DNA topoisomerase II activity
LXN06_RS10165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LXN06_RS10170	COG1609	Transcriptional regulator
LXN06_RS10185	COG2160	L-arabinose isomerase activity
LXN06_RS10205	COG1115	amino acid carrier protein
LXN06_RS10215	COG2181	nitrate reductase activity
LXN06_RS10220	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LXN06_RS10225	COG1140	nitrate reductase beta subunit
LXN06_RS10230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LXN06_RS10245	COG0535	radical SAM domain protein
LXN06_RS10250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXN06_RS10260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LXN06_RS10265	COG2223	nitrite transmembrane transporter activity
LXN06_RS10285	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LXN06_RS10295	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
LXN06_RS10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS10320	COG0477	Major facilitator Superfamily
LXN06_RS10325	COG3420	alginic acid biosynthetic process
LXN06_RS10330	COG1114	Component of the transport system for branched-chain amino acids
LXN06_RS10360	COG1024	Enoyl-CoA hydratase
LXN06_RS10365	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS10370	COG2084	Dehydrogenase
LXN06_RS10375	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS10380	COG1482	cell wall glycoprotein biosynthetic process
LXN06_RS10385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS10385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS10385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS10405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS10405	COG3711	transcriptional antiterminator
LXN06_RS10420	COG1725	Transcriptional regulator
LXN06_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS10430	COG1312	Catalyzes the dehydration of D-mannonate
LXN06_RS10445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LXN06_RS10455	COG1609	Transcriptional regulator
LXN06_RS10460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXN06_RS10465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LXN06_RS10470	COG0640	Transcriptional regulator
LXN06_RS10475	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
LXN06_RS10495	COG2404	hydrolase activity, acting on ester bonds
LXN06_RS10500	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LXN06_RS10510	COG0297	glycogen (starch) synthase activity
LXN06_RS10515	COG2027	D-alanyl-D-alanine carboxypeptidase
LXN06_RS10535	COG1309	transcriptional regulator
LXN06_RS10540	COG1252	NADH dehydrogenase
LXN06_RS10550	COG0166	Belongs to the GPI family
LXN06_RS10560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXN06_RS10565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXN06_RS10570	COG1024	Enoyl-CoA hydratase
LXN06_RS10575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXN06_RS10580	COG0511	ligase activity, forming carbon-carbon bonds
LXN06_RS10585	COG0439	Biotin carboxylase
LXN06_RS10590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS10590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LXN06_RS10595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS10600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS10605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS10610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS10620	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS10625	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS10630	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS10635	COG1733	regulation of RNA biosynthetic process
LXN06_RS10640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LXN06_RS10645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LXN06_RS10655	COG2323	membrane
LXN06_RS10660	COG0306	phosphate transporter
LXN06_RS10665	COG0175	sulfate reduction
LXN06_RS10670	COG1809	phosphosulfolactate synthase activity
LXN06_RS10675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS10680	COG4948	Mandelate Racemase Muconate Lactonizing
LXN06_RS10685	COG2814	Major facilitator Superfamily
LXN06_RS10690	COG0463	Glycosyl transferase, family 2
LXN06_RS10700	COG0493	'glutamate synthase
LXN06_RS10705	COG0069	glutamate synthase activity
LXN06_RS10705	COG0070	glutamate synthase
LXN06_RS10705	COG0067	glutamate synthase
LXN06_RS10710	COG0583	DNA-binding transcription factor activity
LXN06_RS10725	COG1846	Transcriptional regulator
LXN06_RS10735	COG1132	(ABC) transporter
LXN06_RS10745	COG0300	oxidoreductase activity
LXN06_RS10750	COG3848	Pyruvate phosphate dikinase
LXN06_RS10750	COG0574	Belongs to the PEP-utilizing enzyme family
LXN06_RS10755	COG0477	Major facilitator Superfamily
LXN06_RS10760	COG0243	molybdopterin cofactor binding
LXN06_RS10765	COG1846	Transcriptional regulator
LXN06_RS10770	COG2814	Major facilitator Superfamily
LXN06_RS10775	COG0531	amino acid
LXN06_RS10785	COG0531	amino acid
LXN06_RS10790	COG0531	amino acid
LXN06_RS10795	COG0697	spore germination
LXN06_RS10800	COG0488	(ABC) transporter
LXN06_RS10805	COG0840	transmembrane signaling receptor activity
LXN06_RS10810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXN06_RS10815	COG1404	Belongs to the peptidase S8 family
LXN06_RS10825	COG1309	transcriptional regulator
LXN06_RS10830	COG1846	Transcriptional regulator
LXN06_RS10860	COG1309	transcriptional regulator
LXN06_RS10865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS10870	COG3708	Transcriptional regulator
LXN06_RS10880	COG2378	regulation of single-species biofilm formation
LXN06_RS10890	COG0640	Transcriptional regulator
LXN06_RS10905	COG0531	amino acid
LXN06_RS10910	COG0741	lytic transglycosylase activity
LXN06_RS10915	COG1086	Polysaccharide biosynthesis protein
LXN06_RS10935	COG2322	membrane
LXN06_RS10950	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS10955	COG1388	LysM domain
LXN06_RS10955	COG3584	3D domain protein
LXN06_RS10960	COG0514	ATP-dependent DNA helicase (RecQ)
LXN06_RS10980	COG2315	Protein conserved in bacteria
LXN06_RS10990	COG2427	Protein of unknown function (DUF1641)
LXN06_RS10995	COG3383	formate dehydrogenase (NAD+) activity
LXN06_RS11025	COG5444	nuclease activity
LXN06_RS11080	COG0402	S-adenosylhomocysteine deaminase activity
LXN06_RS11095	COG2267	carboxylic ester hydrolase activity
LXN06_RS11110	COG1280	lysine exporter protein (LysE YggA)
LXN06_RS11115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LXN06_RS11125	COG3848	Pyruvate phosphate dikinase
LXN06_RS11125	COG0574	Belongs to the PEP-utilizing enzyme family
LXN06_RS11130	COG1309	transcriptional regulator
LXN06_RS11145	COG2318	DinB family
LXN06_RS11150	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXN06_RS11165	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXN06_RS11180	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS11185	COG2814	Major facilitator Superfamily
LXN06_RS11205	COG1657	PFAM Prenyltransferase squalene oxidase
LXN06_RS11210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXN06_RS11220	COG0733	neurotransmitter:sodium symporter activity
LXN06_RS11225	COG0385	Bile acid
LXN06_RS11230	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXN06_RS11235	COG0567	Dehydrogenase, E1 component
LXN06_RS11240	COG4548	von Willebrand factor, type A
LXN06_RS11245	COG0714	Associated with various cellular activities
LXN06_RS11250	COG2032	superoxide dismutase activity
LXN06_RS11255	COG1388	LysM domain
LXN06_RS11255	COG0791	NLP P60 protein
LXN06_RS11260	COG0534	Mate efflux family protein
LXN06_RS11265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXN06_RS11270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXN06_RS11280	COG2962	Rard protein
LXN06_RS11290	COG4305	rare lipoprotein A
LXN06_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS11305	COG1733	regulation of RNA biosynthetic process
LXN06_RS11310	COG0778	Nitroreductase
LXN06_RS11315	COG0400	carboxylic ester hydrolase activity
LXN06_RS11325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS11330	COG0793	Belongs to the peptidase S41A family
LXN06_RS11330	COG3409	Peptidoglycan-binding domain 1 protein
LXN06_RS11335	COG2226	methyltransferase
LXN06_RS11345	COG1876	peptidase activity
LXN06_RS11350	COG0813	purine-nucleoside phosphorylase activity
LXN06_RS11355	COG0701	Predicted permease
LXN06_RS11375	COG0671	phosphoesterase, PA-phosphatase related
LXN06_RS11395	COG4479	Belongs to the UPF0346 family
LXN06_RS11405	COG1509	lysine 2,3-aminomutase activity
LXN06_RS11410	COG0456	acetyltransferase
LXN06_RS11415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXN06_RS11420	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LXN06_RS11425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LXN06_RS11430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LXN06_RS11445	COG0456	acetyltransferase
LXN06_RS11450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXN06_RS11455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LXN06_RS11460	COG1846	Transcriptional regulator
LXN06_RS11470	COG3706	GGDEF domain
LXN06_RS11475	COG0534	Mate efflux family protein
LXN06_RS11490	COG4698	Protein conserved in bacteria
LXN06_RS11495	COG2755	lipolytic protein G-D-S-L family
LXN06_RS11500	COG1999	signal sequence binding
LXN06_RS11515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LXN06_RS11520	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LXN06_RS11525	COG1272	protein, Hemolysin III
LXN06_RS11530	COG0204	Acyl-transferase
LXN06_RS11535	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LXN06_RS11540	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXN06_RS11550	COG2136	Putative SAM-dependent methyltransferase
LXN06_RS11550	COG2521	methyltransferase
LXN06_RS11560	COG0129	dihydroxy-acid dehydratase activity
LXN06_RS11565	COG1413	lyase activity
LXN06_RS11570	COG1418	mRNA catabolic process
LXN06_RS11575	COG0386	Belongs to the glutathione peroxidase family
LXN06_RS11580	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LXN06_RS11585	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LXN06_RS11590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXN06_RS11600	COG1278	Cold shock
LXN06_RS11620	COG0328	RNA-DNA hybrid ribonuclease activity
LXN06_RS11625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LXN06_RS11630	COG0328	RNA-DNA hybrid ribonuclease activity
LXN06_RS11640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXN06_RS11655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LXN06_RS11665	COG1755	Isoprenylcysteine carboxyl methyltransferase
LXN06_RS11670	COG3424	synthase
LXN06_RS11680	COG2233	PERMEase
LXN06_RS11685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXN06_RS11690	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LXN06_RS11695	COG1199	ATP-dependent helicase activity
LXN06_RS11710	COG0116	Belongs to the methyltransferase superfamily
LXN06_RS11720	COG3599	regulation of cell shape
LXN06_RS11725	COG4474	Belongs to the UPF0398 family
LXN06_RS11735	COG3359	exonuclease
LXN06_RS11740	COG1111	helicase
LXN06_RS11740	COG1205	dead DEAH box helicase
LXN06_RS11745	COG2190	(PTS) system
LXN06_RS11750	COG0071	Belongs to the small heat shock protein (HSP20) family
LXN06_RS11785	COG3331	DNA recombination
LXN06_RS11790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXN06_RS11790	COG4499	WXG100 protein secretion system (Wss), protein YukC
LXN06_RS11800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LXN06_RS11805	COG3935	DnaD domain protein
LXN06_RS11810	COG0017	Asparaginyl-tRNA synthetase
LXN06_RS11815	COG0436	Aminotransferase
LXN06_RS11820	COG5353	protein conserved in bacteria
LXN06_RS11830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LXN06_RS11830	COG1199	ATP-dependent helicase activity
LXN06_RS11835	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LXN06_RS11840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LXN06_RS11845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LXN06_RS11855	COG0617	tRNA 3'-terminal CCA addition
LXN06_RS11860	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS11865	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LXN06_RS11870	COG1803	Methylglyoxal synthase
LXN06_RS11875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LXN06_RS11880	COG1694	Mazg nucleotide pyrophosphohydrolase
LXN06_RS11885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS11895	COG4347	Protein of unknown function (DUF1405)
LXN06_RS11905	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXN06_RS11905	COG2010	Cytochrome c
LXN06_RS11910	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LXN06_RS11915	COG0723	plastoquinol--plastocyanin reductase activity
LXN06_RS11925	COG5582	Belongs to the UPF0302 family
LXN06_RS11930	COG0457	Tetratricopeptide repeat
LXN06_RS11935	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LXN06_RS11940	COG0287	Prephenate dehydrogenase
LXN06_RS11945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LXN06_RS11950	COG0159	tryptophan synthase activity
LXN06_RS11955	COG0133	tryptophan synthase activity
LXN06_RS11960	COG0135	phosphoribosylanthranilate isomerase activity
LXN06_RS11965	COG0134	indole-3-glycerol-phosphate synthase activity
LXN06_RS11970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXN06_RS11975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LXN06_RS11980	COG4401	Chorismate mutase type I
LXN06_RS11985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LXN06_RS11990	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LXN06_RS11995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LXN06_RS12000	COG0105	UTP biosynthetic process
LXN06_RS12005	COG0142	geranyltranstransferase activity
LXN06_RS12010	COG2226	methyltransferase
LXN06_RS12015	COG0142	geranyltranstransferase activity
LXN06_RS12030	COG0776	regulation of translation
LXN06_RS12035	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LXN06_RS12050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LXN06_RS12055	COG1160	GTP binding
LXN06_RS12080	COG1304	FMN binding
LXN06_RS12085	COG0539	negative regulation of cytoplasmic translation
LXN06_RS12090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LXN06_RS12100	COG2959	enzyme of heme biosynthesis
LXN06_RS12105	COG3773	Cell wall hydrolase
LXN06_RS12105	COG3409	Peptidoglycan-binding domain 1 protein
LXN06_RS12110	COG2339	peptidase activity
LXN06_RS12120	COG0492	ferredoxin-NADP+ reductase activity
LXN06_RS12125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXN06_RS12130	COG4862	establishment of competence for transformation
LXN06_RS12135	COG1408	metallophosphoesterase
LXN06_RS12145	COG1388	LysM domain
LXN06_RS12150	COG1266	CAAX protease self-immunity
LXN06_RS12155	COG0514	ATP-dependent DNA helicase (RecQ)
LXN06_RS12160	COG4955	Helix-turn-helix domain
LXN06_RS12165	COG1141	Ferredoxin
LXN06_RS12170	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LXN06_RS12175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LXN06_RS12180	COG0739	heme binding
LXN06_RS12190	COG1595	DNA-templated transcription, initiation
LXN06_RS12195	COG1316	TRANSCRIPTIONal
LXN06_RS12210	COG5002	protein histidine kinase activity
LXN06_RS12215	COG0745	RESPONSE REGULATOR receiver
LXN06_RS12220	COG5002	protein histidine kinase activity
LXN06_RS12225	COG0745	RESPONSE REGULATOR receiver
LXN06_RS12230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXN06_RS12235	COG1333	cytochrome c biogenesis protein
LXN06_RS12240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS12245	COG1187	pseudouridine synthase activity
LXN06_RS12250	COG0700	Nucleoside recognition
LXN06_RS12255	COG2715	membrane protein required for spore maturation
LXN06_RS12260	COG1686	Belongs to the peptidase S11 family
LXN06_RS12270	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LXN06_RS12275	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LXN06_RS12285	COG1547	Domain of unknown function (DUF309)
LXN06_RS12290	COG0456	acetyltransferase
LXN06_RS12295	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LXN06_RS12300	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXN06_RS12300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LXN06_RS12305	COG0307	riboflavin synthase, alpha
LXN06_RS12310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXN06_RS12310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LXN06_RS12335	COG0457	Tetratricopeptide repeat
LXN06_RS12340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LXN06_RS12345	COG4086	secreted protein
LXN06_RS12350	COG4195	phage-related replication protein
LXN06_RS12355	COG0019	diaminopimelate decarboxylase activity
LXN06_RS12365	COG0697	spore germination
LXN06_RS12380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LXN06_RS12415	COG1686	Belongs to the peptidase S11 family
LXN06_RS12420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LXN06_RS12425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LXN06_RS12430	COG4974	Belongs to the 'phage' integrase family
LXN06_RS12440	COG0735	belongs to the Fur family
LXN06_RS12445	COG1300	Membrane
LXN06_RS12450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS12460	COG1953	Uracil, thiamine, allantoin
LXN06_RS12480	COG2153	protein acetylation
LXN06_RS12485	COG1379	DNA repair
LXN06_RS12490	COG0494	nUDIX hydrolase
LXN06_RS12500	COG1309	transcriptional regulator
LXN06_RS12510	COG0667	Aldo Keto reductase
LXN06_RS12520	COG1073	alpha beta
LXN06_RS12530	COG4918	Iron-sulphur cluster biosynthesis
LXN06_RS12540	COG0456	acetyltransferase
LXN06_RS12540	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LXN06_RS12550	COG2329	Antibiotic biosynthesis monooxygenase
LXN06_RS12565	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LXN06_RS12575	COG0747	negative chemotaxis
LXN06_RS12580	COG0601	transmembrane transport
LXN06_RS12585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS12590	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS12600	COG0534	Mate efflux family protein
LXN06_RS12615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXN06_RS12625	COG2211	Major facilitator Superfamily
LXN06_RS12630	COG0346	lactoylglutathione lyase activity
LXN06_RS12635	COG1072	(Pantothenic acid kinase))
LXN06_RS12645	COG1131	(ABC) transporter
LXN06_RS12670	COG2205	protein histidine kinase activity
LXN06_RS12675	COG0745	RESPONSE REGULATOR receiver
LXN06_RS12695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LXN06_RS12700	COG2814	Major facilitator Superfamily
LXN06_RS12710	COG4195	phage-related replication protein
LXN06_RS12725	COG0300	oxidoreductase activity
LXN06_RS12730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS12735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LXN06_RS12740	COG4187	Peptidase family M20/M25/M40
LXN06_RS12745	COG1902	pentaerythritol trinitrate reductase activity
LXN06_RS12750	COG0596	Alpha beta hydrolase
LXN06_RS12755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LXN06_RS12760	COG1234	tRNA 3'-trailer cleavage
LXN06_RS12765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LXN06_RS12780	COG2358	TRAP transporter, solute receptor (TAXI family
LXN06_RS12785	COG2188	Transcriptional regulator
LXN06_RS12790	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS12795	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS12800	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXN06_RS12805	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS12810	COG1785	Belongs to the alkaline phosphatase family
LXN06_RS12815	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS12820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LXN06_RS12825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LXN06_RS12835	COG0706	membrane insertase activity
LXN06_RS12840	COG2195	Cleaves the N-terminal amino acid of tripeptides
LXN06_RS12845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LXN06_RS12855	COG4129	membrane
LXN06_RS12860	COG1126	abc transporter atp-binding protein
LXN06_RS12865	COG0765	amino acid transport
LXN06_RS12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LXN06_RS12880	COG1597	lipid kinase activity
LXN06_RS12885	COG0508	dehydrogenase complex catalyzes the overall conversion of
LXN06_RS12890	COG0022	dehydrogenase e1 component
LXN06_RS12895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LXN06_RS12900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LXN06_RS12905	COG3426	butyrate kinase activity
LXN06_RS12915	COG0280	phosphate acetyltransferase
LXN06_RS12920	COG3829	transcription factor binding
LXN06_RS12920	COG3290	protein histidine kinase activity
LXN06_RS12930	COG0584	glycerophosphoryl diester phosphodiesterase
LXN06_RS12935	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXN06_RS12950	COG0745	RESPONSE REGULATOR receiver
LXN06_RS12955	COG0750	zinc metalloprotease
LXN06_RS12960	COG0497	DNA recombination
LXN06_RS12965	COG1438	arginine binding
LXN06_RS12970	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LXN06_RS12975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LXN06_RS12980	COG0142	geranyltranstransferase activity
LXN06_RS12985	COG1722	exodeoxyribonuclease VII activity
LXN06_RS12990	COG1570	exodeoxyribonuclease VII activity
LXN06_RS12995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LXN06_RS13000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LXN06_RS13005	COG1302	Protein conserved in bacteria
LXN06_RS13010	COG0439	Biotin carboxylase
LXN06_RS13015	COG0511	ligase activity, forming carbon-carbon bonds
LXN06_RS13055	COG3854	ATPases associated with a variety of cellular activities
LXN06_RS13060	COG3854	ATPases associated with a variety of cellular activities
LXN06_RS13070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LXN06_RS13075	COG0006	proline dipeptidase activity
LXN06_RS13080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LXN06_RS13090	COG3872	metal-dependent enzyme
LXN06_RS13100	COG1752	Esterase of the alpha-beta hydrolase superfamily
LXN06_RS13105	COG1321	iron dependent repressor
LXN06_RS13110	COG0095	Lipoate-protein ligase
LXN06_RS13115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXN06_RS13120	COG2113	Glycine betaine
LXN06_RS13125	COG4176	ABC-type proline glycine betaine transport system permease component
LXN06_RS13130	COG4175	Glycine betaine
LXN06_RS13130	COG0517	IMP dehydrogenase activity
LXN06_RS13135	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LXN06_RS13140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LXN06_RS13145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LXN06_RS13150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXN06_RS13175	COG0681	Belongs to the peptidase S26 family
LXN06_RS13200	COG4940	Competence protein ComGF
LXN06_RS13210	COG4970	Tfp pilus assembly protein FimT
LXN06_RS13215	COG4537	Required for transformation and DNA binding
LXN06_RS13220	COG1459	type II secretion system
LXN06_RS13225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LXN06_RS13230	COG1366	Belongs to the anti-sigma-factor antagonist family
LXN06_RS13240	COG1393	Belongs to the ArsC family
LXN06_RS13250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS13260	COG0011	TIGRFAM Protein of
LXN06_RS13270	COG2866	Carboxypeptidase
LXN06_RS13275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS13280	COG1368	sulfuric ester hydrolase activity
LXN06_RS13285	COG1940	carbohydrate kinase activity
LXN06_RS13290	COG4483	Protein conserved in bacteria
LXN06_RS13295	COG0697	spore germination
LXN06_RS13300	COG0705	Rhomboid family
LXN06_RS13300	COG0457	Tetratricopeptide repeat
LXN06_RS13310	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LXN06_RS13315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LXN06_RS13320	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS13335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXN06_RS13345	COG2851	Citrate transporter
LXN06_RS13385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXN06_RS13390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LXN06_RS13395	COG0581	inorganic phosphate transmembrane transporter activity
LXN06_RS13400	COG0573	inorganic phosphate transmembrane transporter activity
LXN06_RS13405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LXN06_RS13410	COG0768	penicillin binding
LXN06_RS13415	COG0477	Major facilitator Superfamily
LXN06_RS13420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LXN06_RS13425	COG2839	Protein conserved in bacteria
LXN06_RS13430	COG5521	maltodextrose utilization protein MalA
LXN06_RS13435	COG1388	LysM domain
LXN06_RS13440	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LXN06_RS13445	COG4709	membrane
LXN06_RS13450	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LXN06_RS13455	COG0735	belongs to the Fur family
LXN06_RS13460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXN06_RS13465	COG1121	(ABC) transporter
LXN06_RS13470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS13480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LXN06_RS13485	COG0513	Belongs to the DEAD box helicase family
LXN06_RS13495	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LXN06_RS13500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LXN06_RS13505	COG2384	SAM-dependent methyltransferase
LXN06_RS13565	COG2010	Cytochrome c
LXN06_RS13570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LXN06_RS13580	COG0358	DNA primase activity
LXN06_RS13585	COG1671	Belongs to the UPF0178 family
LXN06_RS13590	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LXN06_RS13595	COG0517	IMP dehydrogenase activity
LXN06_RS13600	COG0751	glycine-tRNA ligase activity
LXN06_RS13605	COG0752	glycyl-tRNA synthetase alpha subunit
LXN06_RS13610	COG1381	Involved in DNA repair and RecF pathway recombination
LXN06_RS13620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LXN06_RS13625	COG0295	cytidine deaminase activity
LXN06_RS13630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LXN06_RS13635	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LXN06_RS13640	COG1480	7TM receptor with intracellular HD hydrolase
LXN06_RS13645	COG1702	phosphate starvation-inducible protein PhoH
LXN06_RS13650	COG0561	phosphatase activity
LXN06_RS13665	COG4864	UPF0365 protein
LXN06_RS13670	COG1030	water channel activity
LXN06_RS13675	COG1610	YqeY-like protein
LXN06_RS13680	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LXN06_RS13685	COG1283	sodium-dependent phosphate transmembrane transporter activity
LXN06_RS13690	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LXN06_RS13695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LXN06_RS13700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LXN06_RS13705	COG2264	protein methyltransferase activity
LXN06_RS13710	COG0484	heat shock protein binding
LXN06_RS13715	COG0443	Heat shock 70 kDa protein
LXN06_RS13720	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LXN06_RS13725	COG1420	regulation of RNA biosynthetic process
LXN06_RS13730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LXN06_RS13735	COG0481	GTPase activity
LXN06_RS13745	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXN06_RS13750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LXN06_RS13755	COG0268	Binds directly to 16S ribosomal RNA
LXN06_RS13765	COG1733	regulation of RNA biosynthetic process
LXN06_RS13770	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS13780	COG1466	dna polymerase III delta subunit
LXN06_RS13790	COG0658	competence protein
LXN06_RS13790	COG2333	competence protein COMEC
LXN06_RS13795	COG2131	deaminase
LXN06_RS13800	COG1555	photosystem II stabilization
LXN06_RS13800	COG1596	polysaccharide export
LXN06_RS13805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LXN06_RS13810	COG2226	methyltransferase
LXN06_RS13815	COG0799	negative regulation of ribosome biogenesis
LXN06_RS13820	COG1713	HD superfamily hydrolase involved in NAD metabolism
LXN06_RS13825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LXN06_RS13830	COG1534	Rna-binding protein
LXN06_RS13835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LXN06_RS13840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LXN06_RS13845	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LXN06_RS13860	COG2755	lipolytic protein G-D-S-L family
LXN06_RS13870	COG5609	conserved protein (DUF2294)
LXN06_RS13875	COG3383	formate dehydrogenase (NAD+) activity
LXN06_RS13880	COG2427	Protein of unknown function (DUF1641)
LXN06_RS13895	COG1486	melibiose metabolic process
LXN06_RS13915	COG3616	Alanine racemase, N-terminal domain
LXN06_RS13920	COG0251	oxidation-reduction process
LXN06_RS13930	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXN06_RS13935	COG0251	oxidation-reduction process
LXN06_RS13950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS13960	COG2807	transmembrane transport
LXN06_RS13975	COG0789	Transcriptional regulator
LXN06_RS13975	COG4978	Transcriptional regulator
LXN06_RS13995	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS14005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS14065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS14075	COG2197	response regulator
LXN06_RS14080	COG4585	Histidine kinase
LXN06_RS14085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS14090	COG0730	response to heat
LXN06_RS14095	COG0425	Belongs to the sulfur carrier protein TusA family
LXN06_RS14100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS14100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXN06_RS14105	COG0425	Belongs to the sulfur carrier protein TusA family
LXN06_RS14105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXN06_RS14110	COG2210	Belongs to the sulfur carrier protein TusA family
LXN06_RS14115	COG1937	Protein conserved in bacteria
LXN06_RS14155	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXN06_RS14160	COG0113	porphobilinogen synthase activity
LXN06_RS14170	COG1942	4-Oxalocrotonate Tautomerase
LXN06_RS14175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LXN06_RS14180	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LXN06_RS14185	COG1733	regulation of RNA biosynthetic process
LXN06_RS14190	COG3239	Fatty acid desaturase
LXN06_RS14195	COG4585	Histidine kinase
LXN06_RS14200	COG2197	response regulator
LXN06_RS14205	COG0492	ferredoxin-NADP+ reductase activity
LXN06_RS14210	COG0747	negative chemotaxis
LXN06_RS14215	COG0601	transmembrane transport
LXN06_RS14220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LXN06_RS14225	COG0444	Belongs to the ABC transporter superfamily
LXN06_RS14230	COG4608	Belongs to the ABC transporter superfamily
LXN06_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS14265	COG2124	cytochrome p450
LXN06_RS14270	COG0730	response to heat
LXN06_RS14275	COG3507	Belongs to the glycosyl hydrolase 43 family
LXN06_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS14295	COG1621	beta-fructofuranosidase activity
LXN06_RS14300	COG3716	PTS system mannose fructose sorbose family IID component
LXN06_RS14305	COG3715	PTS system
LXN06_RS14310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS14315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS14320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LXN06_RS14320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LXN06_RS14340	COG2169	Transcriptional regulator
LXN06_RS14345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LXN06_RS14350	COG0656	L-ascorbic acid biosynthetic process
LXN06_RS14355	COG2814	Major facilitator Superfamily
LXN06_RS14360	COG1733	regulation of RNA biosynthetic process
LXN06_RS14365	COG3340	Belongs to the peptidase S51 family
LXN06_RS14375	COG1587	Uroporphyrinogen-III synthase
LXN06_RS14385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS14390	COG0583	DNA-binding transcription factor activity
LXN06_RS14395	COG2814	Major facilitator Superfamily
LXN06_RS14415	COG0697	spore germination
LXN06_RS14420	COG2124	cytochrome p450
LXN06_RS14420	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LXN06_RS14425	COG1309	transcriptional regulator
LXN06_RS14430	COG1404	Belongs to the peptidase S8 family
LXN06_RS14435	COG2226	methyltransferase
LXN06_RS14460	COG0626	cystathionine gamma-synthase activity
LXN06_RS14465	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXN06_RS14470	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LXN06_RS14475	COG2226	methyltransferase
LXN06_RS14490	COG0768	penicillin binding
LXN06_RS14495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LXN06_RS14500	COG0572	uridine kinase
LXN06_RS14505	COG0826	peptidase U32
LXN06_RS14510	COG0826	peptidase U32
LXN06_RS14515	COG4122	O-methyltransferase activity
LXN06_RS14520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LXN06_RS14525	COG3906	Belongs to the UPF0473 family
LXN06_RS14530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LXN06_RS14535	COG4472	Bacterial protein of unknown function (DUF965)
LXN06_RS14540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LXN06_RS14545	COG0628	permease
LXN06_RS14560	COG3881	PFAM PRC-barrel domain
LXN06_RS14565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LXN06_RS14570	COG0457	Tetratricopeptide repeat
LXN06_RS14575	COG0482	sulfurtransferase activity
LXN06_RS14580	COG1104	cysteine desulfurase activity
LXN06_RS14585	COG1959	2 iron, 2 sulfur cluster binding
LXN06_RS14590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LXN06_RS14595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LXN06_RS14605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LXN06_RS14610	COG0124	histidyl-tRNA synthetase
LXN06_RS14620	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXN06_RS14620	COG3103	Sh3 type 3 domain protein
LXN06_RS14620	COG4991	sh3 domain protein
LXN06_RS14625	COG1490	D-aminoacyl-tRNA deacylase activity
LXN06_RS14630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LXN06_RS14635	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LXN06_RS14640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LXN06_RS14640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LXN06_RS14645	COG5416	Lipopolysaccharide assembly protein A domain
LXN06_RS14650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXN06_RS14650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LXN06_RS14660	COG2244	polysaccharide biosynthetic process
LXN06_RS14665	COG2323	membrane
LXN06_RS14675	COG1862	Preprotein translocase
LXN06_RS14680	COG0343	queuine tRNA-ribosyltransferase activity
LXN06_RS14685	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LXN06_RS14695	COG2255	four-way junction helicase activity
LXN06_RS14700	COG0632	four-way junction helicase activity
LXN06_RS14710	COG2112	serine threonine protein kinase
LXN06_RS14720	COG2318	DinB family
LXN06_RS14725	COG4195	phage-related replication protein
LXN06_RS14740	COG0217	transcriptional regulatory protein
LXN06_RS14750	COG1388	LysM domain
LXN06_RS14755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LXN06_RS14760	COG0157	Belongs to the NadC ModD family
LXN06_RS14765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LXN06_RS14770	COG1104	cysteine desulfurase activity
LXN06_RS14775	COG1827	regulation of RNA biosynthetic process
LXN06_RS14780	COG0077	Prephenate dehydratase
LXN06_RS14785	COG4492	Belongs to the UPF0735 family
LXN06_RS14790	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LXN06_RS14795	COG3290	protein histidine kinase activity
LXN06_RS14800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LXN06_RS14805	COG2868	ribosomal protein
LXN06_RS14810	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LXN06_RS14815	COG1994	Peptidase M50
LXN06_RS14820	COG0739	heme binding
LXN06_RS14825	COG3832	glyoxalase III activity
LXN06_RS14830	COG0640	Transcriptional regulator
LXN06_RS14835	COG2894	cell division
LXN06_RS14840	COG0850	regulation of cytokinetic process
LXN06_RS14845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LXN06_RS14855	COG1077	Cell shape determining protein MreB Mrl
LXN06_RS14860	COG2003	Belongs to the UPF0758 family
LXN06_RS14865	COG0424	maF-like protein
LXN06_RS14875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LXN06_RS14880	COG0285	dihydrofolate synthase activity
LXN06_RS14885	COG0525	valine-tRNA ligase activity
LXN06_RS14895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXN06_RS14900	COG1388	LysM domain
LXN06_RS14905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LXN06_RS14910	COG0113	porphobilinogen synthase activity
LXN06_RS14915	COG1587	Uroporphyrinogen-III synthase
LXN06_RS14920	COG0181	hydroxymethylbilane synthase activity
LXN06_RS14925	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LXN06_RS14930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LXN06_RS14940	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LXN06_RS14945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LXN06_RS14950	COG1067	ATP-dependent peptidase activity
LXN06_RS14950	COG0470	DNA polymerase III
LXN06_RS14955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LXN06_RS14960	COG0544	peptidyl-prolyl cis-trans isomerase activity
LXN06_RS14965	COG0457	Tetratricopeptide repeat
LXN06_RS14965	COG1477	protein flavinylation
LXN06_RS14970	COG0066	3-isopropylmalate dehydratase activity
LXN06_RS14975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LXN06_RS14980	COG0473	3-isopropylmalate dehydrogenase activity
LXN06_RS14985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LXN06_RS14990	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LXN06_RS14995	COG0440	acetolactate synthase activity
LXN06_RS15000	COG0028	Belongs to the TPP enzyme family
LXN06_RS15005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXN06_RS15015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LXN06_RS15080	COG3778	Protein conserved in bacteria
LXN06_RS15085	COG3299	homolog of phage Mu protein gp47
LXN06_RS15090	COG3628	GPW Gp25 family protein
LXN06_RS15100	COG4193	domain, Protein
LXN06_RS15105	COG1652	LysM domain
LXN06_RS15110	COG3953	SLT domain
LXN06_RS15110	COG5280	Phage tail tape measure protein TP901
LXN06_RS15110	COG3953	SLT domain
LXN06_RS15110	COG5280	Phage tail tape measure protein TP901
LXN06_RS15170	COG4653	Phage capsid family
LXN06_RS15175	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LXN06_RS15185	COG2369	cell adhesion
LXN06_RS15190	COG5518	Phage portal protein
LXN06_RS15195	COG1783	phage Terminase large subunit
LXN06_RS15225	COG5444	nuclease activity
LXN06_RS15230	COG0457	Tetratricopeptide repeat
LXN06_RS15240	COG1396	sequence-specific DNA binding
LXN06_RS15260	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LXN06_RS15275	COG0305	Participates in initiation and elongation during chromosome replication
LXN06_RS15290	COG3723	Recombinational DNA repair protein, rece pathway
LXN06_RS15295	COG5377	YqaJ viral recombinase family
LXN06_RS15340	COG3620	sequence-specific DNA binding
LXN06_RS15350	COG2856	Zn peptidase
LXN06_RS15355	COG4974	Belongs to the 'phage' integrase family
LXN06_RS15365	COG0622	Phosphoesterase
LXN06_RS15370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LXN06_RS15375	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LXN06_RS15380	COG5401	PFAM Sporulation and spore germination
LXN06_RS15385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LXN06_RS15390	COG1846	Transcriptional regulator
LXN06_RS15395	COG2197	response regulator
LXN06_RS15400	COG0300	oxidoreductase activity
LXN06_RS15405	COG0824	Thioesterase
LXN06_RS15410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LXN06_RS15415	COG1053	succinate dehydrogenase
LXN06_RS15420	COG2009	succinate dehydrogenase
LXN06_RS15425	COG1719	4-vinyl reductase, 4VR
LXN06_RS15435	COG0577	efflux transmembrane transporter activity
LXN06_RS15435	COG1136	(ABC) transporter
LXN06_RS15450	COG0527	aspartate kinase activity
LXN06_RS15455	COG0322	excinuclease ABC activity
LXN06_RS15460	COG3118	belongs to the thioredoxin family
LXN06_RS15465	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LXN06_RS15470	COG2086	electron transfer activity
LXN06_RS15475	COG1024	Enoyl-CoA hydratase
LXN06_RS15480	COG1309	transcriptional regulator
LXN06_RS15485	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS15490	COG3766	membrane
LXN06_RS15495	COG1193	negative regulation of DNA recombination
LXN06_RS15500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LXN06_RS15500	COG1796	DNA polymerase
LXN06_RS15505	COG1286	toxin biosynthetic process
LXN06_RS15510	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LXN06_RS15515	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LXN06_RS15525	COG0072	phenylalanine-tRNA ligase activity
LXN06_RS15525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXN06_RS15530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LXN06_RS15535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LXN06_RS15545	COG1966	Carbon starvation protein
LXN06_RS15560	COG0395	ABC-type sugar transport system, permease component
LXN06_RS15565	COG1175	transmembrane transport
LXN06_RS15570	COG1653	transport
LXN06_RS15575	COG0371	Dehydrogenase
LXN06_RS15580	COG0235	Class ii aldolase
LXN06_RS15585	COG1069	ribulokinase activity
LXN06_RS15590	COG2160	L-arabinose isomerase activity
LXN06_RS15595	COG3507	Belongs to the glycosyl hydrolase 43 family
LXN06_RS15600	COG1363	Peptidase, m42
LXN06_RS15610	COG3326	Membrane
LXN06_RS15615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LXN06_RS15620	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LXN06_RS15625	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LXN06_RS15630	COG1346	cytolysis
LXN06_RS15640	COG3540	Alkaline phosphatase
LXN06_RS15645	COG3279	Response regulator of the LytR AlgR family
LXN06_RS15650	COG3275	phosphorelay sensor kinase activity
LXN06_RS15660	COG1011	Hydrolase
LXN06_RS15665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LXN06_RS15675	COG0398	Pfam SNARE associated Golgi protein
LXN06_RS15680	COG1484	DNA-dependent DNA replication
LXN06_RS15685	COG3611	Membrane attachment protein
LXN06_RS15690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LXN06_RS15700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LXN06_RS15705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXN06_RS15710	COG3866	Pectate lyase
LXN06_RS15715	COG0237	dephospho-CoA kinase activity
LXN06_RS15720	COG1971	Probably functions as a manganese efflux pump
LXN06_RS15725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LXN06_RS15730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXN06_RS15730	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LXN06_RS15735	COG5002	protein histidine kinase activity
LXN06_RS15740	COG0745	RESPONSE REGULATOR receiver
LXN06_RS15745	COG0039	L-malate dehydrogenase activity
LXN06_RS15750	COG0538	isocitrate dehydrogenase activity
LXN06_RS15755	COG0372	Belongs to the citrate synthase family
LXN06_RS15760	COG2707	UPF0756 membrane protein
LXN06_RS15765	COG0628	permease
LXN06_RS15770	COG3030	protein affecting phage T7 exclusion by the F plasmid
LXN06_RS15780	COG0205	6-phosphofructokinase activity
LXN06_RS15785	COG0825	malonyl-CoA metabolic process
LXN06_RS15790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LXN06_RS15795	COG0281	malic enzyme
LXN06_RS15800	COG0587	DNA-directed DNA polymerase activity
LXN06_RS15820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LXN06_RS15830	COG4109	DRTGG domain
LXN06_RS15835	COG1695	Transcriptional regulator
LXN06_RS15840	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LXN06_RS15845	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS15855	COG0165	Argininosuccinate lyase
LXN06_RS15860	COG0137	argininosuccinate synthase activity
LXN06_RS15865	COG0521	Mo-molybdopterin cofactor biosynthetic process
LXN06_RS15870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LXN06_RS15875	COG0827	DNA restriction-modification system
LXN06_RS15880	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LXN06_RS15885	COG3874	Sporulation protein YtfJ
LXN06_RS15895	COG1714	RDD family
LXN06_RS15900	COG0616	signal peptide processing
LXN06_RS15905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LXN06_RS15910	COG1566	PFAM secretion protein HlyD family protein
LXN06_RS15915	COG0477	Major facilitator Superfamily
LXN06_RS15925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXN06_RS15935	COG0301	tRNA thio-modification
LXN06_RS15940	COG1104	cysteine desulfurase activity
LXN06_RS15945	COG1114	Component of the transport system for branched-chain amino acids
LXN06_RS15950	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LXN06_RS15955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LXN06_RS15960	COG1309	transcriptional regulator
LXN06_RS15965	COG1956	GAF domain-containing protein
LXN06_RS15970	COG2199	diguanylate cyclase activity
LXN06_RS15970	COG2203	Gaf domain
LXN06_RS15975	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LXN06_RS15985	COG3152	Membrane
LXN06_RS15990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LXN06_RS15995	COG1522	sequence-specific DNA binding
LXN06_RS16005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LXN06_RS16010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LXN06_RS16015	COG0454	-acetyltransferase
LXN06_RS16020	COG0517	IMP dehydrogenase activity
LXN06_RS16025	COG0123	including yeast histone deacetylase and acetoin utilization protein
LXN06_RS16030	COG1360	Flagellar Motor Protein
LXN06_RS16035	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LXN06_RS16040	COG1609	Transcriptional regulator
LXN06_RS16045	COG1605	Chorismate mutase
LXN06_RS16045	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LXN06_RS16055	COG3118	belongs to the thioredoxin family
LXN06_RS16060	COG4980	gas vesicle protein
LXN06_RS16065	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LXN06_RS16070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LXN06_RS16075	COG1674	ftsk spoiiie
LXN06_RS16080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LXN06_RS16085	COG4848	Belongs to the UPF0354 family
LXN06_RS16090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS16100	COG1363	Peptidase, m42
LXN06_RS16105	COG5584	Small secreted protein
LXN06_RS16110	COG0281	malic enzyme
LXN06_RS16115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LXN06_RS16120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LXN06_RS16130	COG0510	thiamine kinase activity
LXN06_RS16135	COG1523	belongs to the glycosyl hydrolase 13 family
LXN06_RS16140	COG1597	lipid kinase activity
LXN06_RS16150	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LXN06_RS16155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LXN06_RS16170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LXN06_RS16175	COG2252	PERMEase
LXN06_RS16180	COG4473	ABC transporter
LXN06_RS16185	COG4473	ABC transporter
LXN06_RS16190	COG1131	(ABC) transporter
LXN06_RS16195	COG1349	DNA-binding transcription factor activity
LXN06_RS16200	COG1187	pseudouridine synthase activity
LXN06_RS16205	COG2244	polysaccharide biosynthetic process
LXN06_RS16210	COG2081	HI0933 family
LXN06_RS16215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LXN06_RS16225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LXN06_RS16230	COG0457	Tetratricopeptide repeat
LXN06_RS16240	COG5578	integral membrane protein
LXN06_RS16245	COG0673	inositol 2-dehydrogenase activity
LXN06_RS16250	COG1653	transport
LXN06_RS16255	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LXN06_RS16260	COG4209	transmembrane transport
LXN06_RS16265	COG2207	Transcriptional regulator
LXN06_RS16270	COG1653	transport
LXN06_RS16275	COG0395	ABC-type sugar transport system, permease component
LXN06_RS16280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXN06_RS16285	COG1073	alpha beta
LXN06_RS16295	COG0583	DNA-binding transcription factor activity
LXN06_RS16300	COG0346	lactoylglutathione lyase activity
LXN06_RS16305	COG0495	leucyl-tRNA aminoacylation
LXN06_RS16315	COG2814	Major facilitator Superfamily
LXN06_RS16325	COG2433	Pfam Transposase IS66
LXN06_RS16330	COG0577	efflux transmembrane transporter activity
LXN06_RS16335	COG1136	(ABC) transporter
LXN06_RS16345	COG1131	(ABC) transporter
LXN06_RS16350	COG1725	Transcriptional regulator
LXN06_RS16360	COG1242	4 iron, 4 sulfur cluster binding
LXN06_RS16365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LXN06_RS16375	COG2267	carboxylic ester hydrolase activity
LXN06_RS16380	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LXN06_RS16385	COG0671	phosphoesterase, PA-phosphatase related
LXN06_RS16390	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS16390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXN06_RS16395	COG0367	asparagine synthase
LXN06_RS16400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LXN06_RS16405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LXN06_RS16420	COG1506	peptidase
LXN06_RS16425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LXN06_RS16430	COG1116	anion transmembrane transporter activity
LXN06_RS16435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LXN06_RS16440	COG0494	nUDIX hydrolase
LXN06_RS16450	COG4824	toxin secretion phage lysis holin
LXN06_RS16455	COG0783	Belongs to the Dps family
LXN06_RS16470	COG1854	S-ribosylhomocysteine lyase activity
LXN06_RS16475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LXN06_RS16480	COG0288	reversible hydration of carbon dioxide
LXN06_RS16485	COG0523	cobalamin synthesis protein
LXN06_RS16490	COG0803	Belongs to the bacterial solute-binding protein 9 family
LXN06_RS16495	COG0254	rRNA binding
LXN06_RS16500	COG1271	oxidase subunit
LXN06_RS16505	COG1294	oxidase, subunit
LXN06_RS16520	COG4948	Mandelate Racemase Muconate Lactonizing
LXN06_RS16525	COG0318	PFAM AMP-dependent synthetase and ligase
LXN06_RS16530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LXN06_RS16535	COG0596	Alpha beta hydrolase
LXN06_RS16540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LXN06_RS16545	COG1169	isochorismate synthase
LXN06_RS16550	COG1575	Belongs to the MenA family. Type 1 subfamily
LXN06_RS16555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LXN06_RS16560	COG0058	SHG alpha-glucan phosphorylase activity
LXN06_RS16565	COG0297	glycogen (starch) synthase activity
LXN06_RS16570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LXN06_RS16575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LXN06_RS16580	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LXN06_RS16700	COG1609	Transcriptional regulator
LXN06_RS16705	COG3859	Proton-coupled thiamine transporter YuaJ
LXN06_RS16710	COG3764	Sortase (surface protein transpeptidase)
LXN06_RS16725	COG0457	Tetratricopeptide repeat
LXN06_RS16730	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LXN06_RS16735	COG0569	domain protein
LXN06_RS16740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXN06_RS16750	COG2318	DinB family
LXN06_RS16760	COG1454	alcohol dehydrogenase
LXN06_RS16765	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS16770	COG1510	regulation of RNA biosynthetic process
LXN06_RS16780	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LXN06_RS16785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LXN06_RS16790	COG2140	Oxalate decarboxylase
LXN06_RS16840	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
LXN06_RS16855	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LXN06_RS16860	COG0726	polysaccharide deacetylase
LXN06_RS16865	COG1408	metallophosphoesterase
LXN06_RS16870	COG1968	undecaprenyl-diphosphatase activity
LXN06_RS16875	COG0628	permease
LXN06_RS16880	COG0673	inositol 2-dehydrogenase activity
LXN06_RS16885	COG0693	protein deglycase activity
LXN06_RS16890	COG0840	transmembrane signaling receptor activity
LXN06_RS16895	COG0840	transmembrane signaling receptor activity
LXN06_RS16900	COG0840	transmembrane signaling receptor activity
LXN06_RS16910	COG2070	2-Nitropropane dioxygenase
LXN06_RS16915	COG0432	Pfam Uncharacterised protein family UPF0047
LXN06_RS16920	COG0366	Alpha amylase catalytic
LXN06_RS16935	COG5297	Belongs to the glycosyl hydrolase family 6
LXN06_RS16940	COG1253	flavin adenine dinucleotide binding
LXN06_RS16945	COG2738	Putative neutral zinc metallopeptidase
LXN06_RS16960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LXN06_RS16970	COG2323	membrane
LXN06_RS16975	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
LXN06_RS16990	COG0166	Belongs to the GPI family
LXN06_RS16995	COG1979	alcohol dehydrogenase
LXN06_RS17000	COG2155	Conserved Protein
LXN06_RS17005	COG1098	S1 RNA binding domain
LXN06_RS17010	COG0436	Aminotransferase
LXN06_RS17015	COG1522	sequence-specific DNA binding
LXN06_RS17020	COG2267	carboxylic ester hydrolase activity
LXN06_RS17035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LXN06_RS17050	COG5018	Exonuclease
LXN06_RS17055	COG2814	Major facilitator Superfamily
LXN06_RS17060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXN06_RS17065	COG3011	Protein conserved in bacteria
LXN06_RS17075	COG3290	protein histidine kinase activity
LXN06_RS17080	COG4565	transcriptional regulatory protein
LXN06_RS17090	COG1183	phosphatidylcholine synthase activity
LXN06_RS17095	COG0586	Pfam SNARE associated Golgi protein
LXN06_RS17100	COG0688	phosphatidylethanolamine metabolic process
LXN06_RS17105	COG3493	citrate carrier protein
LXN06_RS17115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LXN06_RS17115	COG2111	Na H antiporter
LXN06_RS17120	COG2111	Na H antiporter
LXN06_RS17125	COG1006	Multisubunit Na H antiporter MnhC subunit
LXN06_RS17130	COG0651	ATP synthesis coupled electron transport
LXN06_RS17135	COG1863	multisubunit Na H antiporter MnhE subunit
LXN06_RS17140	COG2212	antiporter activity
LXN06_RS17145	COG1320	monovalent cation:proton antiporter activity
LXN06_RS17150	COG2050	protein possibly involved in aromatic compounds catabolism
LXN06_RS17155	COG2197	response regulator
LXN06_RS17160	COG4585	Histidine kinase
LXN06_RS17185	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LXN06_RS17190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LXN06_RS17195	COG1335	isochorismatase
LXN06_RS17200	COG5506	Protein of unknown function (DUF1694)
LXN06_RS17215	COG0628	permease
LXN06_RS17220	COG1959	2 iron, 2 sulfur cluster binding
LXN06_RS17225	COG0657	acetylesterase activity
LXN06_RS17235	COG1418	mRNA catabolic process
LXN06_RS17240	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS17255	COG1511	domain protein
LXN06_RS17260	COG1674	ftsk spoiiie
LXN06_RS17260	COG0433	COG0433 Predicted ATPase
LXN06_RS17265	COG4499	WXG100 protein secretion system (Wss), protein YukC
LXN06_RS17270	COG5417	Belongs to the EsaB family
LXN06_RS17275	COG4842	Belongs to the WXG100 family
LXN06_RS17280	COG1115	amino acid carrier protein
LXN06_RS17285	COG2508	Transcriptional regulator
LXN06_RS17285	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LXN06_RS17290	COG0686	Belongs to the AlaDH PNT family
LXN06_RS17300	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LXN06_RS17305	COG1268	BioY protein
LXN06_RS17310	COG2056	Na+-H+ antiporter family
LXN06_RS17315	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LXN06_RS17320	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LXN06_RS17325	COG3584	3D domain protein
LXN06_RS17340	COG1252	NADH dehydrogenase
LXN06_RS17345	COG0492	ferredoxin-NADP+ reductase activity
LXN06_RS17360	COG0456	acetyltransferase
LXN06_RS17365	COG0316	Belongs to the HesB IscA family
LXN06_RS17370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LXN06_RS17375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXN06_RS17380	COG4844	belongs to the
LXN06_RS17385	COG1252	NADH dehydrogenase
LXN06_RS17405	COG5646	InterPro IPR014922
LXN06_RS17415	COG0457	Tetratricopeptide repeat
LXN06_RS17420	COG3479	Phenolic acid decarboxylase
LXN06_RS17430	COG4837	Protein of unknown function (DUF1462)
LXN06_RS17440	COG1506	peptidase
LXN06_RS17440	COG4946	Tricorn protease homolog
LXN06_RS17440	COG0823	Involved in the tonB-independent uptake of proteins
LXN06_RS17445	COG0083	homoserine kinase activity
LXN06_RS17450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LXN06_RS17455	COG0460	homoserine dehydrogenase
LXN06_RS17465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LXN06_RS17470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LXN06_RS17475	COG0647	UMP catabolic process
LXN06_RS17480	COG2445	Protein of unknown function DUF86
LXN06_RS17485	COG4470	Protein conserved in bacteria
LXN06_RS17500	COG0739	heme binding
LXN06_RS17510	COG0733	neurotransmitter:sodium symporter activity
LXN06_RS17520	COG3377	Domain of unknown function (DUF1805)
LXN06_RS17525	COG0737	Belongs to the 5'-nucleotidase family
LXN06_RS17530	COG0730	response to heat
LXN06_RS17535	COG1801	Protein of unknown function DUF72
LXN06_RS17545	COG3226	Transcriptional regulator
LXN06_RS17560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LXN06_RS17565	COG2508	Transcriptional regulator
LXN06_RS17570	COG2814	Major facilitator Superfamily
LXN06_RS17575	COG1288	antiporter activity
LXN06_RS17580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LXN06_RS17585	COG2356	endonuclease I
LXN06_RS17595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LXN06_RS17610	COG0457	Tetratricopeptide repeat
LXN06_RS17620	COG0719	Fe-S assembly protein
LXN06_RS17625	COG0822	iron-sulfur transferase activity
LXN06_RS17630	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXN06_RS17635	COG0719	Fe-S assembly protein
LXN06_RS17640	COG0396	ATPase activity
LXN06_RS17655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXN06_RS17660	COG1464	Belongs to the NlpA lipoprotein family
LXN06_RS17665	COG2011	ABC-type metal ion transport system permease component
LXN06_RS17670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LXN06_RS17680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LXN06_RS17685	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LXN06_RS17695	COG0509	glycine decarboxylation via glycine cleavage system
LXN06_RS17700	COG1393	Belongs to the ArsC family
LXN06_RS17705	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS17710	COG0183	Belongs to the thiolase family
LXN06_RS17715	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXN06_RS17715	COG1024	Enoyl-CoA hydratase
LXN06_RS17730	COG5577	PFAM Coat F domain
LXN06_RS17745	COG1120	ATPase activity
LXN06_RS17750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS17755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS17760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS17775	COG1686	Belongs to the peptidase S11 family
LXN06_RS17780	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS17785	COG0783	Belongs to the Dps family
LXN06_RS17790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXN06_RS17795	COG0745	RESPONSE REGULATOR receiver
LXN06_RS17800	COG2205	protein histidine kinase activity
LXN06_RS17800	COG2770	Histidine kinase
LXN06_RS17810	COG1309	transcriptional regulator
LXN06_RS17815	COG0114	fumarate hydratase activity
LXN06_RS17825	COG0697	spore germination
LXN06_RS17830	COG0814	amino acid
LXN06_RS17845	COG2197	response regulator
LXN06_RS17850	COG4585	Histidine kinase
LXN06_RS17855	COG4758	membrane
LXN06_RS17865	COG1842	Phage shock protein A
LXN06_RS17870	COG4758	membrane
LXN06_RS17875	COG4677	pectinesterase activity
LXN06_RS17880	COG2096	Adenosyltransferase
LXN06_RS17885	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS17890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LXN06_RS17895	COG3395	kinase activity
LXN06_RS17915	COG1454	alcohol dehydrogenase
LXN06_RS17920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LXN06_RS17925	COG1120	ATPase activity
LXN06_RS17930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS17935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS17940	COG1802	Transcriptional regulator
LXN06_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS17955	COG2721	sulfolactate sulfo-lyase activity
LXN06_RS17960	COG0246	Mannitol dehydrogenase
LXN06_RS17965	COG1609	Transcriptional regulator
LXN06_RS17970	COG2211	Major facilitator Superfamily
LXN06_RS17975	COG1904	glucuronate isomerase
LXN06_RS17980	COG2205	protein histidine kinase activity
LXN06_RS17985	COG0745	RESPONSE REGULATOR receiver
LXN06_RS17990	COG1120	ATPase activity
LXN06_RS17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS18000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS18005	COG0531	amino acid
LXN06_RS18015	COG1988	membrane-bound metal-dependent
LXN06_RS18020	COG1368	sulfuric ester hydrolase activity
LXN06_RS18025	COG2814	Major facilitator Superfamily
LXN06_RS18030	COG0656	L-ascorbic acid biosynthetic process
LXN06_RS18035	COG1940	carbohydrate kinase activity
LXN06_RS18040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LXN06_RS18050	COG3973	AAA domain
LXN06_RS18055	COG2860	membrane
LXN06_RS18060	COG0456	acetyltransferase
LXN06_RS18060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LXN06_RS18065	COG0456	acetyltransferase
LXN06_RS18070	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LXN06_RS18075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LXN06_RS18080	COG2217	Heavy metal translocating P-type atpase
LXN06_RS18085	COG1653	transport
LXN06_RS18090	COG1175	transmembrane transport
LXN06_RS18095	COG0395	ABC-type sugar transport system, permease component
LXN06_RS18100	COG1501	Belongs to the glycosyl hydrolase 31 family
LXN06_RS18105	COG1472	Belongs to the glycosyl hydrolase 3 family
LXN06_RS18110	COG1121	(ABC) transporter
LXN06_RS18115	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LXN06_RS18120	COG0803	Belongs to the bacterial solute-binding protein 9 family
LXN06_RS18135	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LXN06_RS18135	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LXN06_RS18140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS18140	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS18140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LXN06_RS18160	COG2217	Heavy metal translocating P-type atpase
LXN06_RS18165	COG2608	mercury ion transmembrane transporter activity
LXN06_RS18170	COG1937	Protein conserved in bacteria
LXN06_RS18175	COG0693	protein deglycase activity
LXN06_RS18180	COG1349	DNA-binding transcription factor activity
LXN06_RS18185	COG1070	Carbohydrate kinase
LXN06_RS18190	COG4952	isomerase
LXN06_RS18200	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS18200	COG3347	Dehydrogenase
LXN06_RS18210	COG2814	Major facilitator Superfamily
LXN06_RS18215	COG2814	Major facilitator Superfamily
LXN06_RS18225	COG2124	cytochrome p450
LXN06_RS18235	COG1846	Transcriptional regulator
LXN06_RS18245	COG0673	inositol 2-dehydrogenase activity
LXN06_RS18250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LXN06_RS18255	COG1054	Belongs to the UPF0176 family
LXN06_RS18265	COG1191	sigma factor activity
LXN06_RS18275	COG2140	Oxalate decarboxylase
LXN06_RS18315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LXN06_RS18320	COG0557	exoribonuclease II activity
LXN06_RS18325	COG1647	Serine aminopeptidase, S33
LXN06_RS18330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LXN06_RS18335	COG2002	toxin-antitoxin pair type II binding
LXN06_RS18340	COG1476	TRANSCRIPTIONal
LXN06_RS18345	COG1396	sequence-specific DNA binding
LXN06_RS18350	COG1396	sequence-specific DNA binding
LXN06_RS18355	COG1174	glycine betaine transport
LXN06_RS18360	COG1732	Glycine betaine
LXN06_RS18365	COG1174	glycine betaine transport
LXN06_RS18370	COG1125	glycine betaine transport
LXN06_RS18370	COG0517	IMP dehydrogenase activity
LXN06_RS18375	COG1510	regulation of RNA biosynthetic process
LXN06_RS18380	COG2095	MarC family integral membrane protein
LXN06_RS18385	COG3064	Membrane
LXN06_RS18390	COG4640	response to antibiotic
LXN06_RS18395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS18405	COG0693	protein deglycase activity
LXN06_RS18410	COG0148	phosphopyruvate hydratase activity
LXN06_RS18415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LXN06_RS18420	COG0149	triose-phosphate isomerase activity
LXN06_RS18425	COG0126	phosphoglycerate kinase activity
LXN06_RS18430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LXN06_RS18435	COG2390	Transcriptional regulator
LXN06_RS18440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXN06_RS18450	COG1113	amino acid transport
LXN06_RS18470	COG1556	Lactate utilization protein
LXN06_RS18475	COG1139	Iron-sulfur cluster binding protein
LXN06_RS18480	COG0247	lactate metabolic process
LXN06_RS18485	COG2186	Transcriptional regulator
LXN06_RS18490	COG1620	l-lactate permease
LXN06_RS18495	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LXN06_RS18505	COG5039	Polysaccharide pyruvyl transferase
LXN06_RS18510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXN06_RS18515	COG0110	maltose O-acetyltransferase activity
LXN06_RS18520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LXN06_RS18525	COG2244	polysaccharide biosynthetic process
LXN06_RS18530	COG1216	Glycosyl transferase, family 2
LXN06_RS18535	COG5039	Polysaccharide pyruvyl transferase
LXN06_RS18540	COG1216	Glycosyl transferase, family 2
LXN06_RS18550	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS18555	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS18560	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS18565	COG1086	Polysaccharide biosynthesis protein
LXN06_RS18570	COG0489	protein tyrosine kinase activity
LXN06_RS18575	COG3944	biosynthesis protein
LXN06_RS18580	COG1396	sequence-specific DNA binding
LXN06_RS18585	COG2249	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS18590	COG1733	regulation of RNA biosynthetic process
LXN06_RS18595	COG1902	pentaerythritol trinitrate reductase activity
LXN06_RS18600	COG1621	beta-fructofuranosidase activity
LXN06_RS18605	COG1621	beta-fructofuranosidase activity
LXN06_RS18625	COG0740	serine-type endopeptidase activity
LXN06_RS18630	COG1611	Belongs to the LOG family
LXN06_RS18635	COG1694	Mazg nucleotide pyrophosphohydrolase
LXN06_RS18640	COG1078	dGTPase activity
LXN06_RS18645	COG0659	secondary active sulfate transmembrane transporter activity
LXN06_RS18650	COG0288	reversible hydration of carbon dioxide
LXN06_RS18655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXN06_RS18660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LXN06_RS18665	COG0640	Transcriptional regulator
LXN06_RS18670	COG4290	ribonuclease
LXN06_RS18675	COG2732	(Barnase) inhibitor
LXN06_RS18680	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LXN06_RS18685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS18690	COG1481	regulation of sporulation
LXN06_RS18695	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LXN06_RS18700	COG1660	Displays ATPase and GTPase activities
LXN06_RS18705	COG1051	belongs to the nudix hydrolase family
LXN06_RS18710	COG0492	ferredoxin-NADP+ reductase activity
LXN06_RS18715	COG0457	Tetratricopeptide repeat
LXN06_RS18720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LXN06_RS18725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LXN06_RS18725	COG0140	phosphoribosyl-ATP diphosphatase activity
LXN06_RS18730	COG0107	imidazoleglycerol-phosphate synthase activity
LXN06_RS18735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LXN06_RS18740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LXN06_RS18745	COG0131	Imidazoleglycerol-phosphate dehydratase
LXN06_RS18750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LXN06_RS18755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LXN06_RS18760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LXN06_RS18765	COG4990	cell redox homeostasis
LXN06_RS18770	COG5297	Belongs to the glycosyl hydrolase family 6
LXN06_RS18775	COG0110	maltose O-acetyltransferase activity
LXN06_RS18780	COG0546	phosphoglycolate phosphatase activity
LXN06_RS18785	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LXN06_RS18790	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LXN06_RS18795	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LXN06_RS18800	COG1846	Transcriptional regulator
LXN06_RS18805	COG2814	Major facilitator Superfamily
LXN06_RS18810	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LXN06_RS18815	COG1950	PFAM Membrane protein of
LXN06_RS18820	COG1983	PspC domain protein
LXN06_RS18825	COG3595	metallopeptidase activity
LXN06_RS18845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LXN06_RS18850	COG0556	nucleotide-excision repair
LXN06_RS18855	COG4897	Protein conserved in bacteria
LXN06_RS18865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXN06_RS18875	COG0793	Belongs to the peptidase S41A family
LXN06_RS18875	COG3409	Peptidoglycan-binding domain 1 protein
LXN06_RS18880	COG0473	3-isopropylmalate dehydrogenase activity
LXN06_RS18885	COG0791	NLP P60 protein
LXN06_RS18885	COG3883	PFAM NLP P60 protein
LXN06_RS18890	COG2177	Part of the ABC transporter FtsEX involved in
LXN06_RS18895	COG2884	Cell division ATP-binding protein ftsE
LXN06_RS18900	COG2010	Cytochrome c
LXN06_RS18905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS18915	COG0653	protein targeting
LXN06_RS18920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LXN06_RS18935	COG1516	flagellar protein fliS
LXN06_RS18940	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LXN06_RS18945	COG1334	flagellar protein FlaG
LXN06_RS18955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXN06_RS18960	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LXN06_RS18965	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LXN06_RS18975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LXN06_RS18980	COG1256	bacterial-type flagellum assembly
LXN06_RS18980	COG4786	Flagellar basal body rod
LXN06_RS18985	COG3418	PFAM FlgN family protein
LXN06_RS18990	COG2747	anti-sigma28 factor FlgM
LXN06_RS19000	COG1040	competence protein
LXN06_RS19010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LXN06_RS19015	COG1307	EDD domain protein, DegV family
LXN06_RS19020	COG2197	response regulator
LXN06_RS19025	COG4585	Histidine kinase
LXN06_RS19030	COG1739	Uncharacterized protein family UPF0029
LXN06_RS19035	COG1316	TRANSCRIPTIONal
LXN06_RS19045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LXN06_RS19050	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS19055	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS19060	COG3206	protein involved in exopolysaccharide biosynthesis
LXN06_RS19065	COG3307	-O-antigen
LXN06_RS19070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LXN06_RS19075	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LXN06_RS19080	COG0438	transferase activity, transferring glycosyl groups
LXN06_RS19080	COG0297	glycogen (starch) synthase activity
LXN06_RS19085	COG2244	polysaccharide biosynthetic process
LXN06_RS19095	COG0860	N-Acetylmuramoyl-L-alanine amidase
LXN06_RS19095	COG2247	cell wall binding repeat
LXN06_RS19100	COG2247	cell wall binding repeat
LXN06_RS19100	COG2385	sporulation resulting in formation of a cellular spore
LXN06_RS19110	COG1316	TRANSCRIPTIONal
LXN06_RS19115	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LXN06_RS19120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LXN06_RS19130	COG1682	transport, permease protein
LXN06_RS19135	COG0463	Glycosyl transferase, family 2
LXN06_RS19140	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS19140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXN06_RS19145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXN06_RS19150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LXN06_RS19155	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LXN06_RS19160	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LXN06_RS19165	COG4193	domain, Protein
LXN06_RS19170	COG1482	cell wall glycoprotein biosynthetic process
LXN06_RS19180	COG1328	CTP reductase activity
LXN06_RS19190	COG0800	Aldolase
LXN06_RS19195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXN06_RS19200	COG1609	Transcriptional regulator
LXN06_RS19205	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LXN06_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS19215	COG1063	alcohol dehydrogenase
LXN06_RS19225	COG2814	Major facilitator Superfamily
LXN06_RS19230	COG1316	TRANSCRIPTIONal
LXN06_RS19235	COG0561	phosphatase activity
LXN06_RS19240	COG0791	NLP P60 protein
LXN06_RS19250	COG2843	Capsule synthesis protein
LXN06_RS19260	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LXN06_RS19265	COG1609	Transcriptional regulator
LXN06_RS19270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXN06_RS19275	COG1869	D-ribose catabolic process
LXN06_RS19280	COG1129	ABC transporter
LXN06_RS19285	COG1172	Belongs to the binding-protein-dependent transport system permease family
LXN06_RS19290	COG1879	ABC-type sugar transport system periplasmic component
LXN06_RS19295	COG0583	DNA-binding transcription factor activity
LXN06_RS19300	COG3527	Alpha-acetolactate decarboxylase
LXN06_RS19305	COG0028	Belongs to the TPP enzyme family
LXN06_RS19310	COG0583	DNA-binding transcription factor activity
LXN06_RS19315	COG0405	Gamma-glutamyltransferase
LXN06_RS19320	COG1522	sequence-specific DNA binding
LXN06_RS19325	COG2059	Chromate
LXN06_RS19330	COG2059	Chromate
LXN06_RS19335	COG4464	protein tyrosine phosphatase activity
LXN06_RS19340	COG3944	biosynthesis protein
LXN06_RS19350	COG4715	Zinc finger, swim domain protein
LXN06_RS19355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LXN06_RS19360	COG3878	Protein conserved in bacteria
LXN06_RS19365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LXN06_RS19380	COG0561	phosphatase activity
LXN06_RS19385	COG1349	DNA-binding transcription factor activity
LXN06_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS19405	COG3732	PTS system glucitol sorbitol-specific
LXN06_RS19425	COG0629	single-stranded DNA binding
LXN06_RS19440	COG1970	mechanosensitive ion channel activity
LXN06_RS19445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LXN06_RS19450	COG4786	Flagellar basal body rod
LXN06_RS19455	COG4786	Flagellar basal body rod
LXN06_RS19460	COG1077	Cell shape determining protein MreB Mrl
LXN06_RS19465	COG1609	Transcriptional regulator
LXN06_RS19470	COG1846	Transcriptional regulator
LXN06_RS19475	COG2814	Major facilitator Superfamily
LXN06_RS19480	COG0671	phosphoesterase, PA-phosphatase related
LXN06_RS19485	COG1227	inorganic diphosphatase activity
LXN06_RS19490	COG3546	catalase activity
LXN06_RS19495	COG3361	conserved protein (COG2071)
LXN06_RS19510	COG0517	IMP dehydrogenase activity
LXN06_RS19515	COG0598	Magnesium transport protein CorA
LXN06_RS19520	COG1253	flavin adenine dinucleotide binding
LXN06_RS19525	COG0004	ammonium transporteR
LXN06_RS19530	COG0347	Belongs to the P(II) protein family
LXN06_RS19535	COG0740	serine-type endopeptidase activity
LXN06_RS19545	COG0739	heme binding
LXN06_RS19550	COG1247	-acetyltransferase
LXN06_RS19560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXN06_RS19565	COG0477	Major facilitator Superfamily
LXN06_RS19570	COG3251	PFAM MbtH domain protein
LXN06_RS19575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS19580	COG1535	isochorismatase
LXN06_RS19580	COG3433	isochorismatase activity
LXN06_RS19585	COG1021	2,3-dihydroxybenzoate-AMP ligase
LXN06_RS19590	COG1169	isochorismate synthase
LXN06_RS19595	COG1028	Short-chain dehydrogenase reductase Sdr
LXN06_RS19600	COG2819	hydrolase of the alpha beta superfamily
LXN06_RS19605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS19610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LXN06_RS19615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS19620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS19620	COG2207	Transcriptional regulator
LXN06_RS19630	COG2910	NAD(P)H-binding
LXN06_RS19635	COG1959	2 iron, 2 sulfur cluster binding
LXN06_RS19645	COG1994	Peptidase M50
LXN06_RS19650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LXN06_RS19655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LXN06_RS19660	COG2223	nitrite transmembrane transporter activity
LXN06_RS19665	COG3383	formate dehydrogenase (NAD+) activity
LXN06_RS19670	COG2304	oxidoreductase activity
LXN06_RS19675	COG2304	oxidoreductase activity
LXN06_RS19680	COG2385	sporulation resulting in formation of a cellular spore
LXN06_RS19685	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXN06_RS19695	COG4836	Membrane
LXN06_RS19700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LXN06_RS19705	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LXN06_RS19710	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LXN06_RS19715	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LXN06_RS19720	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXN06_RS19725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LXN06_RS19730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LXN06_RS19735	COG0356	it plays a direct role in the translocation of protons across the membrane
LXN06_RS19745	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LXN06_RS19750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LXN06_RS19755	COG4475	Protein of unknown function (DUF436)
LXN06_RS19760	COG0698	ribose 5-phosphate isomerase
LXN06_RS19765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LXN06_RS19770	COG1971	Probably functions as a manganese efflux pump
LXN06_RS19775	COG0009	L-threonylcarbamoyladenylate synthase
LXN06_RS19780	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LXN06_RS19790	COG0738	Major facilitator superfamily
LXN06_RS19795	COG0673	inositol 2-dehydrogenase activity
LXN06_RS19800	COG0561	phosphatase activity
LXN06_RS19805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LXN06_RS19810	COG1609	Transcriptional regulator
LXN06_RS19815	COG2890	protein-(glutamine-N5) methyltransferase activity
LXN06_RS19820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LXN06_RS19825	COG0346	lactoylglutathione lyase activity
LXN06_RS19830	COG0789	Transcriptional regulator
LXN06_RS19835	COG0679	Auxin Efflux Carrier
LXN06_RS19840	COG0281	malic enzyme
LXN06_RS19845	COG1435	thymidine kinase activity
LXN06_RS19850	COG0254	rRNA binding
LXN06_RS19855	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LXN06_RS19860	COG1494	fructose-1,6-bisphosphatase
LXN06_RS19865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LXN06_RS19870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LXN06_RS19875	COG0191	fructose-bisphosphate aldolase activity
LXN06_RS19880	COG2204	response regulator
LXN06_RS19885	COG4821	SIS domain
LXN06_RS19890	COG0504	CTP synthase activity
LXN06_RS19895	COG3343	RNA polymerase activity
LXN06_RS19900	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS19905	COG1960	acyl-CoA dehydrogenase activity
LXN06_RS19910	COG1250	3-hydroxyacyl-CoA dehydrogenase
LXN06_RS19915	COG0183	Belongs to the thiolase family
LXN06_RS19920	COG0247	lactate metabolic process
LXN06_RS19920	COG2181	nitrate reductase activity
LXN06_RS19925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LXN06_RS19935	COG0018	arginyl-trna synthetase
LXN06_RS19940	COG4506	Protein conserved in bacteria
LXN06_RS19945	COG0010	Belongs to the arginase family
LXN06_RS19950	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LXN06_RS19960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LXN06_RS19970	COG1994	Peptidase M50
LXN06_RS19975	COG1942	4-Oxalocrotonate Tautomerase
LXN06_RS19985	COG3465	dGTPase activity
LXN06_RS19990	COG1078	dGTPase activity
LXN06_RS19995	COG4844	belongs to the
LXN06_RS20020	COG2814	Major facilitator Superfamily
LXN06_RS20045	COG1414	Transcriptional regulator
LXN06_RS20055	COG0280	phosphate acetyltransferase
LXN06_RS20060	COG3253	May function as heme-dependent peroxidase
LXN06_RS20070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LXN06_RS20090	COG1131	(ABC) transporter
LXN06_RS20105	COG2363	Small membrane protein
LXN06_RS20110	COG2233	PERMEase
LXN06_RS20125	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LXN06_RS20130	COG1216	Glycosyl transferase, family 2
LXN06_RS20135	COG0351	phosphomethylpyrimidine kinase
LXN06_RS20145	COG1621	beta-fructofuranosidase activity
LXN06_RS20150	COG1263	PTS System
LXN06_RS20150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS20155	COG3711	transcriptional antiterminator
LXN06_RS20165	COG1404	Belongs to the peptidase S8 family
LXN06_RS20175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LXN06_RS20185	COG0778	Nitroreductase
LXN06_RS20190	COG1473	amidohydrolase
LXN06_RS20195	COG0772	Belongs to the SEDS family
LXN06_RS20200	COG0772	Belongs to the SEDS family
LXN06_RS20205	COG3314	Sporulation integral membrane protein YlbJ
LXN06_RS20220	COG0456	acetyltransferase
LXN06_RS20255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LXN06_RS20265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LXN06_RS20270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LXN06_RS20275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXN06_RS20285	COG0655	NAD(P)H dehydrogenase (quinone) activity
LXN06_RS20290	COG3162	membrane
LXN06_RS20295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS20300	COG1070	Carbohydrate kinase
LXN06_RS20305	COG2115	Belongs to the xylose isomerase family
LXN06_RS20310	COG1940	carbohydrate kinase activity
LXN06_RS20315	COG0352	thiamine-phosphate diphosphorylase activity
LXN06_RS20320	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LXN06_RS20325	COG0583	DNA-binding transcription factor activity
LXN06_RS20340	COG1380	Effector of murein hydrolase LrgA
LXN06_RS20345	COG1346	cytolysis
LXN06_RS20350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LXN06_RS20355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LXN06_RS20360	COG0346	lactoylglutathione lyase activity
LXN06_RS20365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LXN06_RS20370	COG1442	glycosyl transferase family 8
LXN06_RS20385	COG4585	Histidine kinase
LXN06_RS20390	COG2197	response regulator
LXN06_RS20395	COG2409	Drug exporters of the RND superfamily
LXN06_RS20400	COG5522	Integral membrane protein (intg_mem_TP0381)
LXN06_RS20405	COG2271	Major facilitator Superfamily
LXN06_RS20410	COG4948	Mandelate Racemase Muconate Lactonizing
LXN06_RS20415	COG0800	Aldolase
LXN06_RS20420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXN06_RS20430	COG2234	aminopeptidase activity
LXN06_RS20435	COG0477	Major facilitator Superfamily
LXN06_RS20450	COG2357	RelA SpoT domain protein
LXN06_RS20465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LXN06_RS20470	COG1696	Membrane protein involved in D-alanine export
LXN06_RS20475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LXN06_RS20480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LXN06_RS20485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LXN06_RS20490	COG2814	Major facilitator Superfamily
LXN06_RS20495	COG1486	melibiose metabolic process
LXN06_RS20500	COG1447	Phosphotransferase system cellobiose-specific component IIA
LXN06_RS20505	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS20510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS20515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LXN06_RS20515	COG3711	transcriptional antiterminator
LXN06_RS20525	COG2094	Belongs to the DNA glycosylase MPG family
LXN06_RS20535	COG0372	Belongs to the citrate synthase family
LXN06_RS20540	COG2079	MmgE PrpD family protein
LXN06_RS20545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LXN06_RS20560	COG1132	(ABC) transporter
LXN06_RS20565	COG2755	lipolytic protein G-D-S-L family
LXN06_RS20580	COG2814	Major facilitator Superfamily
LXN06_RS20585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LXN06_RS20590	COG1131	(ABC) transporter
LXN06_RS20610	COG1595	DNA-templated transcription, initiation
LXN06_RS20615	COG2814	Major facilitator Superfamily
LXN06_RS20625	COG0753	catalase activity
LXN06_RS20630	COG0753	catalase activity
LXN06_RS20635	COG0735	belongs to the Fur family
LXN06_RS20640	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LXN06_RS20650	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LXN06_RS20655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LXN06_RS20660	COG4988	ABC transporter
LXN06_RS20665	COG1294	oxidase, subunit
LXN06_RS20670	COG1271	oxidase subunit
LXN06_RS20675	COG2116	formate transmembrane transporter activity
LXN06_RS20685	COG0281	malic enzyme
LXN06_RS20690	COG1757	Na H antiporter
LXN06_RS20695	COG1027	Aspartate ammonia-lyase
LXN06_RS20700	COG0252	asparaginase activity
LXN06_RS20705	COG1396	sequence-specific DNA binding
LXN06_RS20710	COG2706	6-phosphogluconolactonase activity
LXN06_RS20715	COG0745	RESPONSE REGULATOR receiver
LXN06_RS20720	COG2205	protein histidine kinase activity
LXN06_RS20725	COG1136	(ABC) transporter
LXN06_RS20730	COG0577	efflux transmembrane transporter activity
LXN06_RS20735	COG5294	Protein conserved in bacteria
LXN06_RS20750	COG0726	polysaccharide deacetylase
LXN06_RS20755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LXN06_RS20765	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS20770	COG3493	citrate carrier protein
LXN06_RS20775	COG0584	glycerophosphoryl diester phosphodiesterase
LXN06_RS20790	COG1368	sulfuric ester hydrolase activity
LXN06_RS20800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LXN06_RS20810	COG2235	arginine
LXN06_RS20815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LXN06_RS20825	COG0549	Belongs to the carbamate kinase family
LXN06_RS20835	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS20840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LXN06_RS20850	COG1595	DNA-templated transcription, initiation
LXN06_RS20860	COG2195	Cleaves the N-terminal amino acid of tripeptides
LXN06_RS20875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LXN06_RS20880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LXN06_RS20885	COG0463	Glycosyl transferase, family 2
LXN06_RS20890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXN06_RS20920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXN06_RS20930	COG0753	catalase activity
LXN06_RS20930	COG0693	protein deglycase activity
LXN06_RS20940	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS20945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS20945	COG1263	PTS System
LXN06_RS20945	COG2190	(PTS) system
LXN06_RS20950	COG3711	transcriptional antiterminator
LXN06_RS20955	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LXN06_RS20960	COG1122	ATPase activity
LXN06_RS20965	COG4721	ABC-type cobalt transport system, permease component
LXN06_RS20970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LXN06_RS20980	COG2224	Isocitrate lyase
LXN06_RS20985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LXN06_RS20995	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LXN06_RS21090	COG3209	COG3209 Rhs family protein
LXN06_RS21095	COG0577	efflux transmembrane transporter activity
LXN06_RS21100	COG1136	(ABC) transporter
LXN06_RS21105	COG2205	protein histidine kinase activity
LXN06_RS21110	COG0745	RESPONSE REGULATOR receiver
LXN06_RS21115	COG2723	6-phospho-beta-galactosidase activity
LXN06_RS21120	COG2190	(PTS) system
LXN06_RS21120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS21120	COG1263	PTS System
LXN06_RS21130	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LXN06_RS21150	COG3507	Belongs to the glycosyl hydrolase 43 family
LXN06_RS21155	COG0513	Belongs to the DEAD box helicase family
LXN06_RS21165	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LXN06_RS21170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LXN06_RS21175	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LXN06_RS21180	COG2390	Transcriptional regulator
LXN06_RS21190	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LXN06_RS21195	COG3706	GGDEF domain
LXN06_RS21200	COG5298	Protein conserved in bacteria
LXN06_RS21205	COG1215	transferase activity, transferring glycosyl groups
LXN06_RS21215	COG3977	Valine--pyruvate aminotransferase
LXN06_RS21240	COG0191	fructose-bisphosphate aldolase activity
LXN06_RS21245	COG1082	Xylose isomerase domain protein TIM barrel
LXN06_RS21250	COG1082	Xylose isomerase domain protein TIM barrel
LXN06_RS21255	COG0673	inositol 2-dehydrogenase activity
LXN06_RS21260	COG2814	Major facilitator Superfamily
LXN06_RS21265	COG1082	Xylose isomerase domain protein TIM barrel
LXN06_RS21270	COG3962	Belongs to the TPP enzyme family
LXN06_RS21275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LXN06_RS21280	COG3718	enzyme involved in inositol metabolism
LXN06_RS21285	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS21290	COG1349	DNA-binding transcription factor activity
LXN06_RS21295	COG0667	Aldo Keto reductase
LXN06_RS21300	COG0584	glycerophosphoryl diester phosphodiesterase
LXN06_RS21305	COG2271	Major facilitator Superfamily
LXN06_RS21310	COG0326	Molecular chaperone. Has ATPase activity
LXN06_RS21315	COG0488	(ABC) transporter
LXN06_RS21320	COG0561	phosphatase activity
LXN06_RS21340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LXN06_RS21355	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LXN06_RS21360	COG0577	efflux transmembrane transporter activity
LXN06_RS21365	COG1136	(ABC) transporter
LXN06_RS21370	COG2205	protein histidine kinase activity
LXN06_RS21375	COG0745	RESPONSE REGULATOR receiver
LXN06_RS21385	COG5278	phosphoserine phosphatase activity
LXN06_RS21385	COG0840	transmembrane signaling receptor activity
LXN06_RS21390	COG1115	amino acid carrier protein
LXN06_RS21395	COG0686	Belongs to the AlaDH PNT family
LXN06_RS21400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
LXN06_RS21405	COG1874	Beta-galactosidase
LXN06_RS21410	COG3833	ABC-type maltose transport systems, permease component
LXN06_RS21415	COG1175	transmembrane transport
LXN06_RS21420	COG2182	Extracellular solute-binding protein
LXN06_RS21425	COG1609	Transcriptional regulator
LXN06_RS21435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LXN06_RS21440	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LXN06_RS21445	COG1940	carbohydrate kinase activity
LXN06_RS21475	COG1454	alcohol dehydrogenase
LXN06_RS21475	COG1012	belongs to the aldehyde dehydrogenase family
LXN06_RS21480	COG0450	alkyl hydroperoxide reductase
LXN06_RS21485	COG3634	alkyl hydroperoxide reductase activity
LXN06_RS21510	COG1131	(ABC) transporter
LXN06_RS21515	COG0842	Transport permease protein
LXN06_RS21520	COG4585	Histidine kinase
LXN06_RS21525	COG2197	response regulator
LXN06_RS21550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LXN06_RS21565	COG0456	acetyltransferase
LXN06_RS21580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LXN06_RS21585	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LXN06_RS21590	COG4853	Protein conserved in bacteria
LXN06_RS21595	COG4863	YycH protein
LXN06_RS21600	COG5002	protein histidine kinase activity
LXN06_RS21605	COG0745	RESPONSE REGULATOR receiver
LXN06_RS21635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LXN06_RS21645	COG0305	Participates in initiation and elongation during chromosome replication
LXN06_RS21660	COG3093	addiction module antidote protein HigA
LXN06_RS21665	COG2807	transmembrane transport
LXN06_RS21670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LXN06_RS21675	COG0363	glucosamine-6-phosphate deaminase activity
LXN06_RS21680	COG2188	Transcriptional regulator
LXN06_RS21685	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LXN06_RS21690	COG1263	PTS System
LXN06_RS21690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LXN06_RS21695	COG0359	binds to the 23S rRNA
LXN06_RS21700	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LXN06_RS21705	COG4241	membrane
LXN06_RS21715	COG5577	PFAM Coat F domain
LXN06_RS21720	COG0589	response to stress
LXN06_RS21725	COG0659	secondary active sulfate transmembrane transporter activity
LXN06_RS21730	COG2271	Major facilitator Superfamily
LXN06_RS21735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LXN06_RS21740	COG0629	single-stranded DNA binding
LXN06_RS21745	COG0360	Binds together with S18 to 16S ribosomal RNA
LXN06_RS21750	COG0012	GTP binding
LXN06_RS21755	COG4481	Protein conserved in bacteria
LXN06_RS21760	COG3949	Membrane
LXN06_RS21770	COG1475	DNA binding
LXN06_RS21775	COG1192	Involved in chromosome partitioning
LXN06_RS21780	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LXN06_RS21785	COG1595	DNA-templated transcription, initiation
LXN06_RS21790	COG1475	DNA binding
LXN06_RS21795	COG0357	Ribosomal RNA small subunit methyltransferase G
LXN06_RS21800	COG0445	tRNA wobble uridine modification
LXN06_RS21805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LXN06_RS21810	COG1847	R3H domain protein
LXN06_RS21815	COG0706	membrane insertase activity
LXN06_RS21820	COG0594	ribonuclease P activity
LXN06_RS21880	COG0735	belongs to the Fur family