locus-tag	class	description
B34_RS00010	COG1077	Cell shape determining protein MreB Mrl
B34_RS00015	COG2002	toxin-antitoxin pair type II binding
B34_RS00020	COG3852	Histidine kinase
B34_RS00025	COG0569	domain protein
B34_RS00030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B34_RS00035	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B34_RS00040	COG5503	Protein of unknown function (DUF1447)
B34_RS00045	COG0561	phosphatase activity
B34_RS00050	COG0242	peptide deformylase activity
B34_RS00060	COG0497	DNA recombination
B34_RS00065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_RS00070	COG0022	dehydrogenase e1 component
B34_RS00075	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_RS00080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_RS00085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS00095	COG1982	Orn Lys Arg decarboxylase major
B34_RS00100	COG4476	Belongs to the UPF0223 family
B34_RS00105	COG4493	Belongs to the UPF0637 family
B34_RS00115	COG0483	inositol monophosphate 1-phosphatase activity
B34_RS00135	COG1595	DNA-templated transcription, initiation
B34_RS00150	COG1217	gtp-binding protein TYPA
B34_RS00160	COG1846	Transcriptional regulator
B34_RS00165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B34_RS00170	COG4896	Protein conserved in bacteria
B34_RS00180	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B34_RS00185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B34_RS00190	COG2066	Belongs to the glutaminase family
B34_RS00195	COG4838	Belongs to the UPF0358 family
B34_RS00200	COG0772	Belongs to the SEDS family
B34_RS00205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B34_RS00210	COG1612	heme a metabolic process
B34_RS00215	COG0109	protoheme IX farnesyltransferase activity
B34_RS00220	COG2010	Cytochrome c
B34_RS00220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B34_RS00225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B34_RS00230	COG1845	cytochrome c oxidase, subunit III
B34_RS00235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B34_RS00240	COG3336	cytochrome c oxidase
B34_RS00250	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B34_RS00255	COG2340	Cysteine-rich secretory protein family
B34_RS00270	COG3679	Belongs to the UPF0342 family
B34_RS00275	COG4471	UPF0298 protein
B34_RS00280	COG0742	ribosomal rna small subunit methyltransferase
B34_RS00285	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B34_RS00290	COG3314	Sporulation integral membrane protein YlbJ
B34_RS00295	COG3480	Lon protease (S16) C-terminal proteolytic domain
B34_RS00300	COG1323	Belongs to the UPF0348 family
B34_RS00305	COG1399	metal-binding, possibly nucleic acid-binding protein
B34_RS00310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B34_RS00320	COG0454	-acetyltransferase
B34_RS00325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B34_RS00330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B34_RS00335	COG2001	Belongs to the MraZ family
B34_RS00340	COG0275	rRNA processing
B34_RS00345	COG4839	cell division protein FtsL
B34_RS00350	COG0768	penicillin binding
B34_RS00355	COG0768	penicillin binding
B34_RS00360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B34_RS00365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B34_RS00370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B34_RS00375	COG0772	Belongs to the SEDS family
B34_RS00380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_RS00385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B34_RS00390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B34_RS00395	COG3879	Bacterial protein of unknown function (DUF881)
B34_RS00400	COG3879	Bacterial protein of unknown function (DUF881)
B34_RS00405	COG3856	small basic protein
B34_RS00410	COG0849	cell division
B34_RS00415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B34_RS00420	COG4412	M6 family metalloprotease domain protein
B34_RS00420	COG1404	Belongs to the peptidase S8 family
B34_RS00435	COG1191	sigma factor activity
B34_RS00440	COG1191	sigma factor activity
B34_RS00445	COG1119	ATPase activity
B34_RS00450	COG0500	methyltransferase
B34_RS00455	COG1873	PFAM PRC-barrel domain
B34_RS00460	COG1496	oxidoreductase activity
B34_RS00465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B34_RS00470	COG1799	cell septum assembly
B34_RS00475	COG0762	integral membrane protein
B34_RS00480	COG2302	S4 RNA-binding domain
B34_RS00485	COG3599	regulation of cell shape
B34_RS00490	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B34_RS00495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_RS00500	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B34_RS00505	COG0564	pseudouridine synthase activity
B34_RS00510	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B34_RS00515	COG2233	PERMEase
B34_RS00520	COG0540	Belongs to the ATCase OTCase family
B34_RS00525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B34_RS00530	COG0505	Belongs to the CarA family
B34_RS00535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B34_RS00540	COG0543	2 iron, 2 sulfur cluster binding
B34_RS00545	COG0167	dihydroorotate dehydrogenase activity
B34_RS00550	COG0284	orotidine-5'-phosphate decarboxylase activity
B34_RS00555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B34_RS00565	COG0175	sulfate reduction
B34_RS00570	COG0306	phosphate transporter
B34_RS00575	COG2046	Belongs to the sulfate adenylyltransferase family
B34_RS00580	COG0529	Catalyzes the synthesis of activated sulfate
B34_RS00585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B34_RS00590	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
B34_RS00595	COG1648	precorrin-2 dehydrogenase activity
B34_RS00605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B34_RS00610	COG1561	YicC-like family, N-terminal region
B34_RS00615	COG2052	Domain of unknown function (DUF370)
B34_RS00620	COG0194	GDP metabolic process
B34_RS00625	COG1758	RNA polymerase activity
B34_RS00630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B34_RS00635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B34_RS00640	COG0242	peptide deformylase activity
B34_RS00645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B34_RS00650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B34_RS00650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B34_RS00655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B34_RS00660	COG0631	protein serine/threonine phosphatase activity
B34_RS00665	COG0515	serine threonine protein kinase
B34_RS00665	COG2815	serine threonine protein kinase
B34_RS00670	COG1162	GTPase activity
B34_RS00675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B34_RS00680	COG1564	THIamine pyrophosphokinase
B34_RS00690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B34_RS00695	COG1302	Protein conserved in bacteria
B34_RS00700	COG1461	Dihydroxyacetone kinase
B34_RS00705	COG1760	l-serine dehydratase
B34_RS00710	COG1760	l-serine dehydratase
B34_RS00715	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B34_RS00720	COG1349	DNA-binding transcription factor activity
B34_RS00725	COG0416	fatty acid biosynthetic process
B34_RS00730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B34_RS00735	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS00740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B34_RS00745	COG0571	ribonuclease III activity
B34_RS00750	COG1196	nuclear chromosome segregation
B34_RS00755	COG0552	protein localization to endoplasmic reticulum
B34_RS00760	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B34_RS00765	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B34_RS00770	COG0228	four-way junction DNA binding
B34_RS00775	COG1837	Belongs to the UPF0109 family
B34_RS00785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B34_RS00790	COG0336	Belongs to the RNA methyltransferase TrmD family
B34_RS00795	COG0335	large ribosomal subunit rRNA binding
B34_RS00800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B34_RS00805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B34_RS00815	COG2257	FlhB HrpN YscU SpaS Family
B34_RS00820	COG0045	succinate-CoA ligase (ADP-forming) activity
B34_RS00825	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_RS00830	COG0758	DNA mediated transformation
B34_RS00835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B34_RS00840	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B34_RS00845	COG4974	Belongs to the 'phage' integrase family
B34_RS00850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B34_RS00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B34_RS00860	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B34_RS00865	COG1815	bacterial-type flagellum-dependent cell motility
B34_RS00870	COG1558	bacterial-type flagellum-dependent cell motility
B34_RS00875	COG1677	Flagellar hook-basal body complex protein FliE
B34_RS00880	COG1766	The M ring may be actively involved in energy transduction
B34_RS00885	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_RS00890	COG1317	bacterial-type flagellum organization
B34_RS00895	COG1157	protein secretion by the type III secretion system
B34_RS00900	COG2882	bacterial-type flagellum organization
B34_RS00910	COG3144	bacterial-type flagellum assembly
B34_RS00915	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B34_RS00920	COG4786	Flagellar basal body rod
B34_RS00925	COG1582	Flagellar protein (FlbD)
B34_RS00930	COG1580	Controls the rotational direction of flagella during chemotaxis
B34_RS00935	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_RS00940	COG1776	CheC inhibitor of MCP methylation
B34_RS00940	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B34_RS00945	COG2201	protein-glutamate methylesterase activity
B34_RS00950	COG3190	flagellar
B34_RS00955	COG1338	Plays a role in the flagellum-specific transport system
B34_RS00960	COG1987	bacterial-type flagellum assembly
B34_RS00965	COG1684	flagellar biosynthetic protein fliR
B34_RS00970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B34_RS00975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B34_RS00980	COG1419	protein localization to endoplasmic reticulum
B34_RS00985	COG0455	bacterial-type flagellum organization
B34_RS00990	COG2201	protein-glutamate methylesterase activity
B34_RS00995	COG0643	Histidine kinase
B34_RS00995	COG2198	Histidine kinase
B34_RS01000	COG0835	chemotaxis
B34_RS01005	COG1776	CheC inhibitor of MCP methylation
B34_RS01010	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
B34_RS01015	COG1191	sigma factor activity
B34_RS01025	COG0052	Belongs to the universal ribosomal protein uS2 family
B34_RS01030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B34_RS01035	COG0528	UMP kinase activity
B34_RS01040	COG0233	cytoplasmic translational termination
B34_RS01045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B34_RS01050	COG4589	Belongs to the CDS family
B34_RS01055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B34_RS01060	COG0750	zinc metalloprotease
B34_RS01065	COG0442	prolyl-tRNA aminoacylation
B34_RS01070	COG2176	DNA-directed DNA polymerase activity
B34_RS01100	COG0779	Required for maturation of 30S ribosomal subunits
B34_RS01105	COG0195	Participates in both transcription termination and antitermination
B34_RS01110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B34_RS01115	COG1358	cellular component organization or biogenesis
B34_RS01120	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B34_RS01125	COG1550	Protein conserved in bacteria
B34_RS01130	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B34_RS01135	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B34_RS01140	COG0196	riboflavin kinase activity
B34_RS01145	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B34_RS01150	COG1185	polyribonucleotide nucleotidyltransferase activity
B34_RS01155	COG0726	polysaccharide deacetylase
B34_RS01160	COG0612	Peptidase, M16
B34_RS01165	COG1873	PFAM PRC-barrel domain
B34_RS01170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_RS01175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B34_RS01180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B34_RS01185	COG0527	aspartate kinase activity
B34_RS01195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B34_RS01200	COG0740	serine-type endopeptidase activity
B34_RS01210	COG4980	gas vesicle protein
B34_RS01210	COG1674	ftsk spoiiie
B34_RS01215	COG2188	Transcriptional regulator
B34_RS01220	COG2814	Major facilitator Superfamily
B34_RS01225	COG0612	Peptidase, M16
B34_RS01230	COG0612	Peptidase, M16
B34_RS01235	COG0300	oxidoreductase activity
B34_RS01250	COG1426	Protein conserved in bacteria
B34_RS01255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B34_RS01260	COG1546	Belongs to the CinA family
B34_RS01260	COG1058	Belongs to the CinA family
B34_RS01270	COG1418	mRNA catabolic process
B34_RS01275	COG1692	metallophosphoesterase
B34_RS01280	COG2359	stage V sporulation protein S
B34_RS01290	COG1063	alcohol dehydrogenase
B34_RS01295	COG0156	8-amino-7-oxononanoate synthase activity
B34_RS01300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B34_RS01305	COG4550	Control of competence regulator ComK, YlbF/YmcA
B34_RS01315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B34_RS01320	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B34_RS01325	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B34_RS01330	COG5444	nuclease activity
B34_RS01350	COG0523	cobalamin synthesis protein
B34_RS01360	COG1247	-acetyltransferase
B34_RS01375	COG1231	oxidoreductase activity
B34_RS01380	COG3619	membrane
B34_RS01385	COG3263	regulation of cellular component size
B34_RS01395	COG2267	carboxylic ester hydrolase activity
B34_RS01405	COG0393	Putative heavy-metal-binding
B34_RS01410	COG0398	Pfam SNARE associated Golgi protein
B34_RS01415	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_RS01420	COG1819	glycosyl
B34_RS01425	COG0531	amino acid
B34_RS01430	COG5577	PFAM Coat F domain
B34_RS01445	COG1309	transcriptional regulator
B34_RS01450	COG3631	Ketosteroid isomerase-related protein
B34_RS01455	COG0702	epimerase
B34_RS01465	COG1764	response to oxidative stress
B34_RS01470	COG2076	Multidrug Resistance protein
B34_RS01475	COG2076	Multidrug Resistance protein
B34_RS01490	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B34_RS01495	COG1923	regulation of RNA biosynthetic process
B34_RS01510	COG1780	Probably involved in ribonucleotide reductase function
B34_RS01515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_RS01520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_RS01525	COG4112	unkown
B34_RS01535	COG0822	iron-sulfur transferase activity
B34_RS01540	COG0735	belongs to the Fur family
B34_RS01545	COG1802	Transcriptional regulator
B34_RS01550	COG0697	spore germination
B34_RS01585	COG1309	transcriptional regulator
B34_RS01620	COG4282	regulation of fungal-type cell wall biogenesis
B34_RS01625	COG5444	nuclease activity
B34_RS01650	COG0464	growth
B34_RS01660	COG0840	transmembrane signaling receptor activity
B34_RS01665	COG2002	toxin-antitoxin pair type II binding
B34_RS01670	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS01675	COG5444	nuclease activity
B34_RS01710	COG2814	Major facilitator Superfamily
B34_RS01715	COG0457	Tetratricopeptide repeat
B34_RS01735	COG5632	N-Acetylmuramoyl-L-alanine amidase
B34_RS01745	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_RS01755	COG2433	Pfam Transposase IS66
B34_RS01765	COG1196	nuclear chromosome segregation
B34_RS01765	COG0741	lytic transglycosylase activity
B34_RS01765	COG0739	heme binding
B34_RS01770	COG0739	heme binding
B34_RS01770	COG1196	nuclear chromosome segregation
B34_RS01770	COG0741	lytic transglycosylase activity
B34_RS01835	COG0582	viral genome integration into host DNA
B34_RS01930	COG4373	Mu-like prophage FluMu protein gp28
B34_RS01960	COG0776	regulation of translation
B34_RS01990	COG1404	Belongs to the peptidase S8 family
B34_RS02065	COG3655	Transcriptional regulator
B34_RS02185	COG0582	viral genome integration into host DNA
B34_RS02210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B34_RS02265	COG1793	dna ligase
B34_RS02340	COG2887	Belongs to the helicase family. UvrD subfamily
B34_RS02350	COG0305	Participates in initiation and elongation during chromosome replication
B34_RS02355	COG0358	DNA primase activity
B34_RS02360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B34_RS02365	COG0587	DNA-directed DNA polymerase activity
B34_RS02375	COG0587	DNA-directed DNA polymerase activity
B34_RS02385	COG0587	DNA-directed DNA polymerase activity
B34_RS02390	COG3584	3D domain protein
B34_RS02430	COG1780	Probably involved in ribonucleotide reductase function
B34_RS02435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_RS02440	COG1372	Participates in initiation and elongation during chromosome replication
B34_RS02440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_RS02455	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B34_RS02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS02480	COG0756	dUTP diphosphatase activity
B34_RS02515	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B34_RS02540	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B34_RS02560	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
B34_RS02570	COG3331	DNA recombination
B34_RS02580	COG0464	growth
B34_RS02585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B34_RS02590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B34_RS02595	COG0789	Transcriptional regulator
B34_RS02600	COG0174	glutamine synthetase
B34_RS02640	COG1073	alpha beta
B34_RS02680	COG1309	transcriptional regulator
B34_RS02685	COG2076	Multidrug Resistance protein
B34_RS02690	COG2076	Multidrug Resistance protein
B34_RS02715	COG3546	catalase activity
B34_RS02740	COG1846	Transcriptional regulator
B34_RS02750	COG0346	lactoylglutathione lyase activity
B34_RS02755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B34_RS02760	COG0655	NAD(P)H dehydrogenase (quinone) activity
B34_RS02780	COG3209	COG3209 Rhs family protein
B34_RS02785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B34_RS02790	COG1388	LysM domain
B34_RS02795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B34_RS02800	COG4224	UPF0291 protein
B34_RS02805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B34_RS02815	COG3763	UPF0154 protein
B34_RS02825	COG0785	Cytochrome C biogenesis protein
B34_RS02830	COG2201	protein-glutamate methylesterase activity
B34_RS02835	COG4846	Membrane protein involved in cytochrome C biogenesis
B34_RS02845	COG0071	Belongs to the small heat shock protein (HSP20) family
B34_RS02860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B34_RS02865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS02885	COG0824	Thioesterase
B34_RS02910	COG4841	protein insertion into membrane
B34_RS02915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B34_RS02920	COG1832	CoA-binding protein
B34_RS02925	COG0187	DNA topoisomerase II activity
B34_RS02930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B34_RS02935	COG1609	Transcriptional regulator
B34_RS02950	COG2160	L-arabinose isomerase activity
B34_RS02970	COG1115	amino acid carrier protein
B34_RS02980	COG2181	nitrate reductase activity
B34_RS02985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B34_RS02990	COG1140	nitrate reductase beta subunit
B34_RS02995	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B34_RS03010	COG0535	radical SAM domain protein
B34_RS03015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_RS03025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_RS03030	COG2223	nitrite transmembrane transporter activity
B34_RS03040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B34_RS03050	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B34_RS03060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
B34_RS03070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_RS03080	COG0477	Major facilitator Superfamily
B34_RS03085	COG3420	alginic acid biosynthetic process
B34_RS03090	COG1114	Component of the transport system for branched-chain amino acids
B34_RS03095	COG1064	alcohol dehydrogenase
B34_RS03100	COG0789	Transcriptional regulator
B34_RS03125	COG1024	Enoyl-CoA hydratase
B34_RS03130	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS03135	COG2084	Dehydrogenase
B34_RS03140	COG1960	acyl-CoA dehydrogenase activity
B34_RS03145	COG1482	cell wall glycoprotein biosynthetic process
B34_RS03150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS03150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS03150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS03170	COG3711	transcriptional antiterminator
B34_RS03170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS03185	COG1725	Transcriptional regulator
B34_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS03195	COG1312	Catalyzes the dehydration of D-mannonate
B34_RS03210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
B34_RS03220	COG1609	Transcriptional regulator
B34_RS03225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_RS03230	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B34_RS03235	COG0640	Transcriptional regulator
B34_RS03245	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B34_RS03260	COG1649	PFAM Uncharacterised BCR, COG1649
B34_RS03270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B34_RS03280	COG2027	D-alanyl-D-alanine carboxypeptidase
B34_RS03285	COG2323	membrane
B34_RS03290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_RS03300	COG2323	membrane
B34_RS03315	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_RS03340	COG3546	catalase activity
B34_RS03360	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS03380	COG1252	NADH dehydrogenase
B34_RS03395	COG0166	Belongs to the GPI family
B34_RS03405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_RS03410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B34_RS03415	COG1024	Enoyl-CoA hydratase
B34_RS03420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B34_RS03425	COG0511	ligase activity, forming carbon-carbon bonds
B34_RS03430	COG0439	Biotin carboxylase
B34_RS03435	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS03440	COG1960	acyl-CoA dehydrogenase activity
B34_RS03445	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_RS03450	COG1733	regulation of RNA biosynthetic process
B34_RS03455	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B34_RS03460	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B34_RS03470	COG2323	membrane
B34_RS03475	COG0306	phosphate transporter
B34_RS03480	COG0175	sulfate reduction
B34_RS03485	COG1809	phosphosulfolactate synthase activity
B34_RS03490	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS03500	COG2814	Major facilitator Superfamily
B34_RS03505	COG0463	Glycosyl transferase, family 2
B34_RS03520	COG0493	'glutamate synthase
B34_RS03525	COG0067	glutamate synthase
B34_RS03525	COG0069	glutamate synthase activity
B34_RS03525	COG0070	glutamate synthase
B34_RS03530	COG0583	DNA-binding transcription factor activity
B34_RS03550	COG1846	Transcriptional regulator
B34_RS03560	COG1132	(ABC) transporter
B34_RS03570	COG0300	oxidoreductase activity
B34_RS03585	COG0477	Major facilitator Superfamily
B34_RS03590	COG0243	molybdopterin cofactor binding
B34_RS03595	COG1846	Transcriptional regulator
B34_RS03600	COG2814	Major facilitator Superfamily
B34_RS03605	COG0531	amino acid
B34_RS03615	COG0531	amino acid
B34_RS03620	COG0531	amino acid
B34_RS03625	COG0697	spore germination
B34_RS03630	COG0488	(ABC) transporter
B34_RS03635	COG0840	transmembrane signaling receptor activity
B34_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_RS03645	COG1404	Belongs to the peptidase S8 family
B34_RS03655	COG1309	transcriptional regulator
B34_RS03660	COG1846	Transcriptional regulator
B34_RS03690	COG1309	transcriptional regulator
B34_RS03695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS03700	COG3708	Transcriptional regulator
B34_RS03710	COG2378	regulation of single-species biofilm formation
B34_RS03720	COG0640	Transcriptional regulator
B34_RS03725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS03735	COG0531	amino acid
B34_RS03740	COG0741	lytic transglycosylase activity
B34_RS03745	COG1086	Polysaccharide biosynthesis protein
B34_RS03770	COG2322	membrane
B34_RS03785	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS03790	COG3584	3D domain protein
B34_RS03790	COG1388	LysM domain
B34_RS03795	COG0514	ATP-dependent DNA helicase (RecQ)
B34_RS03815	COG2315	Protein conserved in bacteria
B34_RS03835	COG2427	Protein of unknown function (DUF1641)
B34_RS03840	COG3383	formate dehydrogenase (NAD+) activity
B34_RS03865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
B34_RS03910	COG0402	S-adenosylhomocysteine deaminase activity
B34_RS03925	COG2267	carboxylic ester hydrolase activity
B34_RS03940	COG1280	lysine exporter protein (LysE YggA)
B34_RS03945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_RS03955	COG0574	Belongs to the PEP-utilizing enzyme family
B34_RS03955	COG3848	Pyruvate phosphate dikinase
B34_RS03960	COG1309	transcriptional regulator
B34_RS03975	COG2318	DinB family
B34_RS03980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B34_RS03985	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS04005	COG2814	Major facilitator Superfamily
B34_RS04025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B34_RS04035	COG0733	neurotransmitter:sodium symporter activity
B34_RS04040	COG0385	Bile acid
B34_RS04045	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_RS04050	COG0567	Dehydrogenase, E1 component
B34_RS04055	COG4548	von Willebrand factor, type A
B34_RS04060	COG0714	Associated with various cellular activities
B34_RS04065	COG2032	superoxide dismutase activity
B34_RS04070	COG1388	LysM domain
B34_RS04070	COG0791	NLP P60 protein
B34_RS04080	COG0534	Mate efflux family protein
B34_RS04085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_RS04090	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_RS04100	COG2962	Rard protein
B34_RS04110	COG4305	rare lipoprotein A
B34_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS04125	COG1733	regulation of RNA biosynthetic process
B34_RS04130	COG0778	Nitroreductase
B34_RS04135	COG0400	carboxylic ester hydrolase activity
B34_RS04145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS04150	COG0793	Belongs to the peptidase S41A family
B34_RS04150	COG3409	Peptidoglycan-binding domain 1 protein
B34_RS04155	COG2226	methyltransferase
B34_RS04165	COG1876	peptidase activity
B34_RS04170	COG0813	purine-nucleoside phosphorylase activity
B34_RS04175	COG0701	Predicted permease
B34_RS04190	COG0671	phosphoesterase, PA-phosphatase related
B34_RS04205	COG4479	Belongs to the UPF0346 family
B34_RS04215	COG1509	lysine 2,3-aminomutase activity
B34_RS04220	COG0456	acetyltransferase
B34_RS04225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_RS04230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B34_RS04235	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B34_RS04240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B34_RS04255	COG0456	acetyltransferase
B34_RS04260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B34_RS04265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B34_RS04270	COG1846	Transcriptional regulator
B34_RS04280	COG3706	GGDEF domain
B34_RS04285	COG0534	Mate efflux family protein
B34_RS04300	COG4698	Protein conserved in bacteria
B34_RS04305	COG2755	lipolytic protein G-D-S-L family
B34_RS04310	COG1999	signal sequence binding
B34_RS04325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B34_RS04330	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B34_RS04335	COG1272	protein, Hemolysin III
B34_RS04340	COG0204	Acyl-transferase
B34_RS04345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B34_RS04355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B34_RS04370	COG2136	Putative SAM-dependent methyltransferase
B34_RS04370	COG2521	methyltransferase
B34_RS04380	COG0129	dihydroxy-acid dehydratase activity
B34_RS04385	COG1413	lyase activity
B34_RS04390	COG1418	mRNA catabolic process
B34_RS04395	COG0386	Belongs to the glutathione peroxidase family
B34_RS04400	COG2759	Belongs to the formate--tetrahydrofolate ligase family
B34_RS04405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B34_RS04410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_RS04420	COG1278	Cold shock
B34_RS04440	COG0328	RNA-DNA hybrid ribonuclease activity
B34_RS04445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
B34_RS04450	COG0328	RNA-DNA hybrid ribonuclease activity
B34_RS04460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_RS04470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B34_RS04480	COG1755	Isoprenylcysteine carboxyl methyltransferase
B34_RS04485	COG3424	synthase
B34_RS04490	COG0456	acetyltransferase
B34_RS04495	COG2233	PERMEase
B34_RS04500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_RS04505	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B34_RS04510	COG1199	ATP-dependent helicase activity
B34_RS04520	COG0116	Belongs to the methyltransferase superfamily
B34_RS04530	COG3599	regulation of cell shape
B34_RS04535	COG4474	Belongs to the UPF0398 family
B34_RS04545	COG3359	exonuclease
B34_RS04550	COG1205	dead DEAH box helicase
B34_RS04550	COG1111	helicase
B34_RS04555	COG2190	(PTS) system
B34_RS04560	COG0071	Belongs to the small heat shock protein (HSP20) family
B34_RS04595	COG3331	DNA recombination
B34_RS04600	COG4499	WXG100 protein secretion system (Wss), protein YukC
B34_RS04600	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_RS04610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B34_RS04615	COG3935	DnaD domain protein
B34_RS04620	COG0017	Asparaginyl-tRNA synthetase
B34_RS04625	COG0436	Aminotransferase
B34_RS04630	COG5353	protein conserved in bacteria
B34_RS04640	COG1199	ATP-dependent helicase activity
B34_RS04640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B34_RS04645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B34_RS04650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B34_RS04655	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B34_RS04670	COG0617	tRNA 3'-terminal CCA addition
B34_RS04675	COG0438	transferase activity, transferring glycosyl groups
B34_RS04680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B34_RS04685	COG1803	Methylglyoxal synthase
B34_RS04690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B34_RS04695	COG1694	Mazg nucleotide pyrophosphohydrolase
B34_RS04700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS04710	COG4347	Protein of unknown function (DUF1405)
B34_RS04715	COG2010	Cytochrome c
B34_RS04715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B34_RS04720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B34_RS04725	COG0723	plastoquinol--plastocyanin reductase activity
B34_RS04735	COG5582	Belongs to the UPF0302 family
B34_RS04740	COG0457	Tetratricopeptide repeat
B34_RS04745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B34_RS04750	COG0287	Prephenate dehydrogenase
B34_RS04755	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B34_RS04760	COG0159	tryptophan synthase activity
B34_RS04765	COG0133	tryptophan synthase activity
B34_RS04770	COG0135	phosphoribosylanthranilate isomerase activity
B34_RS04775	COG0134	indole-3-glycerol-phosphate synthase activity
B34_RS04780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_RS04785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B34_RS04790	COG4401	Chorismate mutase type I
B34_RS04795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B34_RS04800	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B34_RS04805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B34_RS04810	COG0105	UTP biosynthetic process
B34_RS04815	COG0142	geranyltranstransferase activity
B34_RS04820	COG2226	methyltransferase
B34_RS04825	COG0142	geranyltranstransferase activity
B34_RS04840	COG0776	regulation of translation
B34_RS04845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B34_RS04865	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B34_RS04870	COG1160	GTP binding
B34_RS04895	COG1304	FMN binding
B34_RS04900	COG0539	negative regulation of cytoplasmic translation
B34_RS04905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B34_RS04910	COG2959	enzyme of heme biosynthesis
B34_RS04915	COG3773	Cell wall hydrolase
B34_RS04915	COG3409	Peptidoglycan-binding domain 1 protein
B34_RS04920	COG2339	peptidase activity
B34_RS04930	COG0492	ferredoxin-NADP+ reductase activity
B34_RS04935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B34_RS04940	COG4862	establishment of competence for transformation
B34_RS04945	COG1408	metallophosphoesterase
B34_RS04955	COG1388	LysM domain
B34_RS04960	COG1266	CAAX protease self-immunity
B34_RS04965	COG0514	ATP-dependent DNA helicase (RecQ)
B34_RS04970	COG4955	Helix-turn-helix domain
B34_RS04975	COG1141	Ferredoxin
B34_RS04980	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B34_RS04985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B34_RS04990	COG0739	heme binding
B34_RS05000	COG1595	DNA-templated transcription, initiation
B34_RS05005	COG1316	TRANSCRIPTIONal
B34_RS05020	COG5002	protein histidine kinase activity
B34_RS05025	COG0745	RESPONSE REGULATOR receiver
B34_RS05030	COG5002	protein histidine kinase activity
B34_RS05035	COG0745	RESPONSE REGULATOR receiver
B34_RS05040	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B34_RS05045	COG1333	cytochrome c biogenesis protein
B34_RS05050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS05055	COG1187	pseudouridine synthase activity
B34_RS05060	COG0700	Nucleoside recognition
B34_RS05065	COG2715	membrane protein required for spore maturation
B34_RS05070	COG1686	Belongs to the peptidase S11 family
B34_RS05080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B34_RS05085	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B34_RS05095	COG1547	Domain of unknown function (DUF309)
B34_RS05100	COG0456	acetyltransferase
B34_RS05105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B34_RS05110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B34_RS05110	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B34_RS05115	COG0307	riboflavin synthase, alpha
B34_RS05120	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B34_RS05120	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B34_RS05145	COG0457	Tetratricopeptide repeat
B34_RS05150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B34_RS05155	COG4086	secreted protein
B34_RS05160	COG4195	phage-related replication protein
B34_RS05165	COG0019	diaminopimelate decarboxylase activity
B34_RS05175	COG0697	spore germination
B34_RS05190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_RS05215	COG2172	sigma factor antagonist activity
B34_RS05225	COG1686	Belongs to the peptidase S11 family
B34_RS05230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
B34_RS05235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B34_RS05240	COG4974	Belongs to the 'phage' integrase family
B34_RS05250	COG0735	belongs to the Fur family
B34_RS05255	COG1300	Membrane
B34_RS05260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS05285	COG2153	protein acetylation
B34_RS05290	COG1379	DNA repair
B34_RS05295	COG0494	nUDIX hydrolase
B34_RS05305	COG1309	transcriptional regulator
B34_RS05315	COG0667	Aldo Keto reductase
B34_RS05325	COG1073	alpha beta
B34_RS05335	COG4918	Iron-sulphur cluster biosynthesis
B34_RS05345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B34_RS05345	COG0456	acetyltransferase
B34_RS05350	COG2329	Antibiotic biosynthesis monooxygenase
B34_RS05360	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
B34_RS05370	COG0747	negative chemotaxis
B34_RS05375	COG0601	transmembrane transport
B34_RS05380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS05385	COG0444	Belongs to the ABC transporter superfamily
B34_RS05390	COG0534	Mate efflux family protein
B34_RS05405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B34_RS05415	COG2211	Major facilitator Superfamily
B34_RS05420	COG0346	lactoylglutathione lyase activity
B34_RS05425	COG1072	(Pantothenic acid kinase))
B34_RS05440	COG1131	(ABC) transporter
B34_RS05460	COG4195	phage-related replication protein
B34_RS05470	COG0300	oxidoreductase activity
B34_RS05475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS05480	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_RS05485	COG4187	Peptidase family M20/M25/M40
B34_RS05490	COG1902	pentaerythritol trinitrate reductase activity
B34_RS05495	COG0596	Alpha beta hydrolase
B34_RS05500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B34_RS05505	COG1234	tRNA 3'-trailer cleavage
B34_RS05510	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B34_RS05525	COG2358	TRAP transporter, solute receptor (TAXI family
B34_RS05530	COG2188	Transcriptional regulator
B34_RS05535	COG2723	6-phospho-beta-galactosidase activity
B34_RS05540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS05545	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_RS05550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS05560	COG1785	Belongs to the alkaline phosphatase family
B34_RS05565	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS05570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B34_RS05575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B34_RS05585	COG0706	membrane insertase activity
B34_RS05590	COG2195	Cleaves the N-terminal amino acid of tripeptides
B34_RS05595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B34_RS05600	COG4129	membrane
B34_RS05605	COG1126	abc transporter atp-binding protein
B34_RS05610	COG0765	amino acid transport
B34_RS05615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_RS05625	COG1597	lipid kinase activity
B34_RS05630	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_RS05635	COG0022	dehydrogenase e1 component
B34_RS05640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_RS05645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_RS05650	COG3426	butyrate kinase activity
B34_RS05660	COG0280	phosphate acetyltransferase
B34_RS05665	COG3290	protein histidine kinase activity
B34_RS05665	COG3829	transcription factor binding
B34_RS05675	COG0584	glycerophosphoryl diester phosphodiesterase
B34_RS05680	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS05695	COG1045	serine acetyltransferase
B34_RS05705	COG0745	RESPONSE REGULATOR receiver
B34_RS05710	COG0750	zinc metalloprotease
B34_RS05715	COG0497	DNA recombination
B34_RS05720	COG1438	arginine binding
B34_RS05725	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B34_RS05730	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B34_RS05735	COG0142	geranyltranstransferase activity
B34_RS05740	COG1722	exodeoxyribonuclease VII activity
B34_RS05745	COG1570	exodeoxyribonuclease VII activity
B34_RS05750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B34_RS05755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B34_RS05760	COG1302	Protein conserved in bacteria
B34_RS05765	COG0439	Biotin carboxylase
B34_RS05770	COG0511	ligase activity, forming carbon-carbon bonds
B34_RS05810	COG3854	ATPases associated with a variety of cellular activities
B34_RS05820	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B34_RS05825	COG0006	proline dipeptidase activity
B34_RS05830	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B34_RS05840	COG3872	metal-dependent enzyme
B34_RS05850	COG1752	Esterase of the alpha-beta hydrolase superfamily
B34_RS05855	COG1321	iron dependent repressor
B34_RS05860	COG0095	Lipoate-protein ligase
B34_RS05865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_RS05870	COG2113	Glycine betaine
B34_RS05875	COG4176	ABC-type proline glycine betaine transport system permease component
B34_RS05880	COG0517	IMP dehydrogenase activity
B34_RS05880	COG4175	Glycine betaine
B34_RS05885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B34_RS05890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B34_RS05895	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B34_RS05900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B34_RS05925	COG0681	Belongs to the peptidase S26 family
B34_RS05950	COG4940	Competence protein ComGF
B34_RS05960	COG4970	Tfp pilus assembly protein FimT
B34_RS05965	COG4537	Required for transformation and DNA binding
B34_RS06040	COG3778	Protein conserved in bacteria
B34_RS06045	COG3299	homolog of phage Mu protein gp47
B34_RS06050	COG3628	GPW Gp25 family protein
B34_RS06060	COG4193	domain, Protein
B34_RS06065	COG1652	LysM domain
B34_RS06070	COG3953	SLT domain
B34_RS06070	COG5280	Phage tail tape measure protein TP901
B34_RS06070	COG5280	Phage tail tape measure protein TP901
B34_RS06070	COG3953	SLT domain
B34_RS06130	COG4653	Phage capsid family
B34_RS06135	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B34_RS06145	COG2369	cell adhesion
B34_RS06150	COG5518	Phage portal protein
B34_RS06155	COG1783	phage Terminase large subunit
B34_RS06185	COG5444	nuclease activity
B34_RS06190	COG0457	Tetratricopeptide repeat
B34_RS06215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_RS06235	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
B34_RS06250	COG0305	Participates in initiation and elongation during chromosome replication
B34_RS06265	COG3723	Recombinational DNA repair protein, rece pathway
B34_RS06270	COG5377	YqaJ viral recombinase family
B34_RS06315	COG1396	sequence-specific DNA binding
B34_RS06320	COG2856	Zn peptidase
B34_RS06335	COG1459	type II secretion system
B34_RS06340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B34_RS06345	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_RS06355	COG1393	Belongs to the ArsC family
B34_RS06365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS06375	COG0011	TIGRFAM Protein of
B34_RS06385	COG2866	Carboxypeptidase
B34_RS06390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS06395	COG1368	sulfuric ester hydrolase activity
B34_RS06400	COG1940	carbohydrate kinase activity
B34_RS06405	COG4483	Protein conserved in bacteria
B34_RS06410	COG0697	spore germination
B34_RS06415	COG0705	Rhomboid family
B34_RS06415	COG0457	Tetratricopeptide repeat
B34_RS06420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B34_RS06425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B34_RS06430	COG0438	transferase activity, transferring glycosyl groups
B34_RS06445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B34_RS06450	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B34_RS06455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B34_RS06460	COG0581	inorganic phosphate transmembrane transporter activity
B34_RS06465	COG0573	inorganic phosphate transmembrane transporter activity
B34_RS06470	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B34_RS06475	COG0768	penicillin binding
B34_RS06480	COG0477	Major facilitator Superfamily
B34_RS06485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B34_RS06490	COG2839	Protein conserved in bacteria
B34_RS06495	COG5521	maltodextrose utilization protein MalA
B34_RS06500	COG1388	LysM domain
B34_RS06505	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B34_RS06510	COG4709	membrane
B34_RS06515	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B34_RS06520	COG0735	belongs to the Fur family
B34_RS06525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B34_RS06530	COG1121	(ABC) transporter
B34_RS06535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS06545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B34_RS06550	COG0513	Belongs to the DEAD box helicase family
B34_RS06560	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B34_RS06565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B34_RS06570	COG2384	SAM-dependent methyltransferase
B34_RS06625	COG5444	nuclease activity
B34_RS06640	COG2010	Cytochrome c
B34_RS06645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B34_RS06650	COG0358	DNA primase activity
B34_RS06655	COG1671	Belongs to the UPF0178 family
B34_RS06660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B34_RS06665	COG0517	IMP dehydrogenase activity
B34_RS06670	COG0751	glycine-tRNA ligase activity
B34_RS06675	COG0752	glycyl-tRNA synthetase alpha subunit
B34_RS06680	COG1381	Involved in DNA repair and RecF pathway recombination
B34_RS06690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B34_RS06695	COG0295	cytidine deaminase activity
B34_RS06700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B34_RS06705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B34_RS06710	COG1480	7TM receptor with intracellular HD hydrolase
B34_RS06715	COG1702	phosphate starvation-inducible protein PhoH
B34_RS06720	COG0561	phosphatase activity
B34_RS06735	COG4864	UPF0365 protein
B34_RS06740	COG1030	water channel activity
B34_RS06745	COG1610	YqeY-like protein
B34_RS06750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B34_RS06755	COG1283	sodium-dependent phosphate transmembrane transporter activity
B34_RS06760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B34_RS06765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B34_RS06770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B34_RS06775	COG2264	protein methyltransferase activity
B34_RS06780	COG0484	heat shock protein binding
B34_RS06785	COG0443	Heat shock 70 kDa protein
B34_RS06790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B34_RS06795	COG1420	regulation of RNA biosynthetic process
B34_RS06800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B34_RS06805	COG0481	GTPase activity
B34_RS06815	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS06820	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B34_RS06825	COG0268	Binds directly to 16S ribosomal RNA
B34_RS06830	COG1466	dna polymerase III delta subunit
B34_RS06840	COG0658	competence protein
B34_RS06840	COG2333	competence protein COMEC
B34_RS06845	COG2131	deaminase
B34_RS06850	COG1555	photosystem II stabilization
B34_RS06850	COG1596	polysaccharide export
B34_RS06855	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_RS06860	COG2226	methyltransferase
B34_RS06865	COG0799	negative regulation of ribosome biogenesis
B34_RS06870	COG1713	HD superfamily hydrolase involved in NAD metabolism
B34_RS06875	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B34_RS06880	COG1534	Rna-binding protein
B34_RS06885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B34_RS06890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B34_RS06895	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B34_RS06905	COG2755	lipolytic protein G-D-S-L family
B34_RS06910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_RS06915	COG5609	conserved protein (DUF2294)
B34_RS06920	COG3383	formate dehydrogenase (NAD+) activity
B34_RS06925	COG2427	Protein of unknown function (DUF1641)
B34_RS06960	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS07015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_RS07015	COG0425	Belongs to the sulfur carrier protein TusA family
B34_RS07025	COG2197	response regulator
B34_RS07030	COG4585	Histidine kinase
B34_RS07035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS07040	COG0730	response to heat
B34_RS07045	COG0425	Belongs to the sulfur carrier protein TusA family
B34_RS07050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_RS07050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS07055	COG0425	Belongs to the sulfur carrier protein TusA family
B34_RS07055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_RS07060	COG2210	Belongs to the sulfur carrier protein TusA family
B34_RS07065	COG1937	Protein conserved in bacteria
B34_RS07105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B34_RS07110	COG0113	porphobilinogen synthase activity
B34_RS07115	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B34_RS07120	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
B34_RS07125	COG1733	regulation of RNA biosynthetic process
B34_RS07130	COG3239	Fatty acid desaturase
B34_RS07135	COG4585	Histidine kinase
B34_RS07140	COG2197	response regulator
B34_RS07145	COG0492	ferredoxin-NADP+ reductase activity
B34_RS07155	COG0601	transmembrane transport
B34_RS07160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS07165	COG0444	Belongs to the ABC transporter superfamily
B34_RS07170	COG4608	Belongs to the ABC transporter superfamily
B34_RS07190	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS07205	COG2124	cytochrome p450
B34_RS07210	COG0730	response to heat
B34_RS07225	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS07230	COG1621	beta-fructofuranosidase activity
B34_RS07235	COG3716	PTS system mannose fructose sorbose family IID component
B34_RS07245	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS07250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS07255	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B34_RS07255	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B34_RS07275	COG2169	Transcriptional regulator
B34_RS07280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B34_RS07285	COG0656	L-ascorbic acid biosynthetic process
B34_RS07290	COG2814	Major facilitator Superfamily
B34_RS07295	COG1733	regulation of RNA biosynthetic process
B34_RS07300	COG3340	Belongs to the peptidase S51 family
B34_RS07305	COG1587	Uroporphyrinogen-III synthase
B34_RS07315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS07320	COG0583	DNA-binding transcription factor activity
B34_RS07325	COG2814	Major facilitator Superfamily
B34_RS07335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B34_RS07335	COG2124	cytochrome p450
B34_RS07340	COG1309	transcriptional regulator
B34_RS07345	COG1404	Belongs to the peptidase S8 family
B34_RS07350	COG2226	methyltransferase
B34_RS07375	COG0626	cystathionine gamma-synthase activity
B34_RS07380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_RS07385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B34_RS07390	COG2226	methyltransferase
B34_RS07405	COG0768	penicillin binding
B34_RS07410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B34_RS07415	COG0572	uridine kinase
B34_RS07420	COG0826	peptidase U32
B34_RS07425	COG0826	peptidase U32
B34_RS07430	COG4122	O-methyltransferase activity
B34_RS07435	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B34_RS07440	COG3906	Belongs to the UPF0473 family
B34_RS07445	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B34_RS07450	COG4472	Bacterial protein of unknown function (DUF965)
B34_RS07455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B34_RS07460	COG0628	permease
B34_RS07475	COG3881	PFAM PRC-barrel domain
B34_RS07480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B34_RS07485	COG0457	Tetratricopeptide repeat
B34_RS07490	COG0482	sulfurtransferase activity
B34_RS07495	COG1104	cysteine desulfurase activity
B34_RS07500	COG1959	2 iron, 2 sulfur cluster binding
B34_RS07505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B34_RS07510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B34_RS07520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B34_RS07525	COG0124	histidyl-tRNA synthetase
B34_RS07530	COG3103	Sh3 type 3 domain protein
B34_RS07530	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS07530	COG4991	sh3 domain protein
B34_RS07535	COG1490	D-aminoacyl-tRNA deacylase activity
B34_RS07540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B34_RS07545	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_RS07550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B34_RS07550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B34_RS07555	COG5416	Lipopolysaccharide assembly protein A domain
B34_RS07560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B34_RS07560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B34_RS07570	COG2244	polysaccharide biosynthetic process
B34_RS07575	COG2323	membrane
B34_RS07585	COG1862	Preprotein translocase
B34_RS07590	COG0343	queuine tRNA-ribosyltransferase activity
B34_RS07595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B34_RS07605	COG2255	four-way junction helicase activity
B34_RS07610	COG0632	four-way junction helicase activity
B34_RS07620	COG2112	serine threonine protein kinase
B34_RS07630	COG2318	DinB family
B34_RS07635	COG4195	phage-related replication protein
B34_RS07650	COG0217	transcriptional regulatory protein
B34_RS07660	COG1388	LysM domain
B34_RS07665	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B34_RS07670	COG0157	Belongs to the NadC ModD family
B34_RS07675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B34_RS07680	COG1104	cysteine desulfurase activity
B34_RS07685	COG1827	regulation of RNA biosynthetic process
B34_RS07690	COG0077	Prephenate dehydratase
B34_RS07695	COG4492	Belongs to the UPF0735 family
B34_RS07700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B34_RS07705	COG3290	protein histidine kinase activity
B34_RS07710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B34_RS07715	COG2868	ribosomal protein
B34_RS07720	COG0261	This protein binds to 23S rRNA in the presence of protein L20
B34_RS07725	COG1994	Peptidase M50
B34_RS07730	COG0739	heme binding
B34_RS07735	COG3832	glyoxalase III activity
B34_RS07740	COG0640	Transcriptional regulator
B34_RS07745	COG2894	cell division
B34_RS07750	COG0850	regulation of cytokinetic process
B34_RS07755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B34_RS07765	COG1077	Cell shape determining protein MreB Mrl
B34_RS07770	COG2003	Belongs to the UPF0758 family
B34_RS07775	COG0424	maF-like protein
B34_RS07785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B34_RS07790	COG0285	dihydrofolate synthase activity
B34_RS07795	COG0525	valine-tRNA ligase activity
B34_RS07805	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B34_RS07810	COG1388	LysM domain
B34_RS07815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B34_RS07820	COG0113	porphobilinogen synthase activity
B34_RS07825	COG1587	Uroporphyrinogen-III synthase
B34_RS07830	COG0181	hydroxymethylbilane synthase activity
B34_RS07835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B34_RS07840	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B34_RS07850	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B34_RS07855	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B34_RS07860	COG0470	DNA polymerase III
B34_RS07860	COG1067	ATP-dependent peptidase activity
B34_RS07865	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
B34_RS07870	COG0544	peptidyl-prolyl cis-trans isomerase activity
B34_RS07875	COG0457	Tetratricopeptide repeat
B34_RS07875	COG1477	protein flavinylation
B34_RS07880	COG0066	3-isopropylmalate dehydratase activity
B34_RS07885	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B34_RS07890	COG0473	3-isopropylmalate dehydrogenase activity
B34_RS07895	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B34_RS07900	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B34_RS07905	COG0440	acetolactate synthase activity
B34_RS07910	COG0028	Belongs to the TPP enzyme family
B34_RS07915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_RS07945	COG5518	Phage portal protein
B34_RS07950	COG1783	phage Terminase large subunit
B34_RS07985	COG5444	nuclease activity
B34_RS07990	COG0457	Tetratricopeptide repeat
B34_RS08010	COG0622	Phosphoesterase
B34_RS08015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
B34_RS08020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B34_RS08025	COG5401	PFAM Sporulation and spore germination
B34_RS08030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B34_RS08035	COG1846	Transcriptional regulator
B34_RS08040	COG2197	response regulator
B34_RS08045	COG4221	oxidoreductase activity
B34_RS08050	COG0824	Thioesterase
B34_RS08055	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B34_RS08060	COG1053	succinate dehydrogenase
B34_RS08065	COG2009	succinate dehydrogenase
B34_RS08070	COG1719	4-vinyl reductase, 4VR
B34_RS08075	COG0527	aspartate kinase activity
B34_RS08080	COG0322	excinuclease ABC activity
B34_RS08085	COG3118	belongs to the thioredoxin family
B34_RS08090	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B34_RS08095	COG2086	electron transfer activity
B34_RS08100	COG1024	Enoyl-CoA hydratase
B34_RS08105	COG1309	transcriptional regulator
B34_RS08110	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS08115	COG3766	membrane
B34_RS08120	COG1193	negative regulation of DNA recombination
B34_RS08125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B34_RS08125	COG1796	DNA polymerase
B34_RS08130	COG1286	toxin biosynthetic process
B34_RS08135	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B34_RS08140	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B34_RS08165	COG1137	ATPase activity
B34_RS08180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_RS08180	COG0072	phenylalanine-tRNA ligase activity
B34_RS08185	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B34_RS08190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B34_RS08200	COG1966	Carbon starvation protein
B34_RS08215	COG0395	ABC-type sugar transport system, permease component
B34_RS08220	COG1175	transmembrane transport
B34_RS08225	COG1653	transport
B34_RS08230	COG0371	Dehydrogenase
B34_RS08235	COG0235	Class ii aldolase
B34_RS08240	COG1069	ribulokinase activity
B34_RS08250	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_RS08255	COG1363	Peptidase, m42
B34_RS08265	COG3326	Membrane
B34_RS08270	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B34_RS08275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
B34_RS08280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B34_RS08285	COG1346	cytolysis
B34_RS08295	COG3540	Alkaline phosphatase
B34_RS08300	COG3279	Response regulator of the LytR AlgR family
B34_RS08305	COG3275	phosphorelay sensor kinase activity
B34_RS08315	COG1011	Hydrolase
B34_RS08320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B34_RS08330	COG0398	Pfam SNARE associated Golgi protein
B34_RS08335	COG1484	DNA-dependent DNA replication
B34_RS08340	COG3611	Membrane attachment protein
B34_RS08345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B34_RS08360	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B34_RS08365	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B34_RS08370	COG3866	Pectate lyase
B34_RS08375	COG0237	dephospho-CoA kinase activity
B34_RS08380	COG1971	Probably functions as a manganese efflux pump
B34_RS08385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B34_RS08390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_RS08390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B34_RS08395	COG5002	protein histidine kinase activity
B34_RS08400	COG0745	RESPONSE REGULATOR receiver
B34_RS08405	COG0039	L-malate dehydrogenase activity
B34_RS08410	COG0538	isocitrate dehydrogenase activity
B34_RS08415	COG0372	Belongs to the citrate synthase family
B34_RS08420	COG2707	UPF0756 membrane protein
B34_RS08425	COG0628	permease
B34_RS08430	COG3030	protein affecting phage T7 exclusion by the F plasmid
B34_RS08440	COG0205	6-phosphofructokinase activity
B34_RS08445	COG0825	malonyl-CoA metabolic process
B34_RS08450	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B34_RS08455	COG0281	malic enzyme
B34_RS08460	COG0587	DNA-directed DNA polymerase activity
B34_RS08480	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B34_RS08490	COG4109	DRTGG domain
B34_RS08495	COG1695	Transcriptional regulator
B34_RS08500	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B34_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS08510	COG0165	Argininosuccinate lyase
B34_RS08515	COG0137	argininosuccinate synthase activity
B34_RS08520	COG0521	Mo-molybdopterin cofactor biosynthetic process
B34_RS08525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B34_RS08530	COG0827	DNA restriction-modification system
B34_RS08535	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B34_RS08540	COG3874	Sporulation protein YtfJ
B34_RS08550	COG1714	RDD family
B34_RS08555	COG0616	signal peptide processing
B34_RS08560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B34_RS08565	COG1566	PFAM secretion protein HlyD family protein
B34_RS08580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_RS08590	COG0301	tRNA thio-modification
B34_RS08595	COG1104	cysteine desulfurase activity
B34_RS08600	COG1114	Component of the transport system for branched-chain amino acids
B34_RS08610	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B34_RS08615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B34_RS08620	COG1309	transcriptional regulator
B34_RS08625	COG1956	GAF domain-containing protein
B34_RS08640	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B34_RS08655	COG3152	Membrane
B34_RS08665	COG1522	sequence-specific DNA binding
B34_RS08670	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B34_RS08675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B34_RS08680	COG0454	-acetyltransferase
B34_RS08685	COG0517	IMP dehydrogenase activity
B34_RS08690	COG0123	including yeast histone deacetylase and acetoin utilization protein
B34_RS08695	COG1360	Flagellar Motor Protein
B34_RS08700	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B34_RS08705	COG1609	Transcriptional regulator
B34_RS08710	COG1605	Chorismate mutase
B34_RS08710	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B34_RS08720	COG3118	belongs to the thioredoxin family
B34_RS08725	COG4980	gas vesicle protein
B34_RS08730	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B34_RS08735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B34_RS08740	COG1674	ftsk spoiiie
B34_RS08745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_RS08750	COG4848	Belongs to the UPF0354 family
B34_RS08755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS08765	COG1363	Peptidase, m42
B34_RS08770	COG5584	Small secreted protein
B34_RS08775	COG0281	malic enzyme
B34_RS08780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS08785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B34_RS08795	COG0510	thiamine kinase activity
B34_RS08805	COG1597	lipid kinase activity
B34_RS08815	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B34_RS08820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_RS08835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_RS08840	COG2252	PERMEase
B34_RS08845	COG1349	DNA-binding transcription factor activity
B34_RS08850	COG1187	pseudouridine synthase activity
B34_RS08855	COG2244	polysaccharide biosynthetic process
B34_RS08860	COG2081	HI0933 family
B34_RS08865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B34_RS08875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B34_RS08880	COG0457	Tetratricopeptide repeat
B34_RS08890	COG5578	integral membrane protein
B34_RS08895	COG0673	inositol 2-dehydrogenase activity
B34_RS08900	COG1653	transport
B34_RS08905	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B34_RS08910	COG4209	transmembrane transport
B34_RS08915	COG2207	Transcriptional regulator
B34_RS08925	COG1653	transport
B34_RS08930	COG0395	ABC-type sugar transport system, permease component
B34_RS08935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_RS08940	COG1073	alpha beta
B34_RS08950	COG0583	DNA-binding transcription factor activity
B34_RS08955	COG0346	lactoylglutathione lyase activity
B34_RS08960	COG0495	leucyl-tRNA aminoacylation
B34_RS08970	COG2814	Major facilitator Superfamily
B34_RS08980	COG2433	Pfam Transposase IS66
B34_RS08985	COG0577	efflux transmembrane transporter activity
B34_RS08990	COG1136	(ABC) transporter
B34_RS09000	COG1131	(ABC) transporter
B34_RS09005	COG1725	Transcriptional regulator
B34_RS09015	COG1242	4 iron, 4 sulfur cluster binding
B34_RS09020	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B34_RS09025	COG1301	dicarboxylic acid transport
B34_RS09035	COG2267	carboxylic ester hydrolase activity
B34_RS09040	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B34_RS09045	COG0671	phosphoesterase, PA-phosphatase related
B34_RS09050	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_RS09050	COG0438	transferase activity, transferring glycosyl groups
B34_RS09055	COG0367	asparagine synthase
B34_RS09060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B34_RS09065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B34_RS09080	COG1506	peptidase
B34_RS09085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B34_RS09090	COG1116	anion transmembrane transporter activity
B34_RS09095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B34_RS09100	COG0494	nUDIX hydrolase
B34_RS09110	COG4824	toxin secretion phage lysis holin
B34_RS09115	COG0783	Belongs to the Dps family
B34_RS09130	COG1854	S-ribosylhomocysteine lyase activity
B34_RS09135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B34_RS09140	COG0288	reversible hydration of carbon dioxide
B34_RS09145	COG0523	cobalamin synthesis protein
B34_RS09150	COG0803	Belongs to the bacterial solute-binding protein 9 family
B34_RS09155	COG0254	rRNA binding
B34_RS09160	COG1271	oxidase subunit
B34_RS09165	COG1294	oxidase, subunit
B34_RS09180	COG4948	Mandelate Racemase Muconate Lactonizing
B34_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS09190	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B34_RS09195	COG0596	Alpha beta hydrolase
B34_RS09200	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B34_RS09205	COG1169	isochorismate synthase
B34_RS09210	COG1575	Belongs to the MenA family. Type 1 subfamily
B34_RS09215	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B34_RS09220	COG0058	SHG alpha-glucan phosphorylase activity
B34_RS09225	COG0297	glycogen (starch) synthase activity
B34_RS09230	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B34_RS09240	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B34_RS09365	COG1609	Transcriptional regulator
B34_RS09370	COG3859	Proton-coupled thiamine transporter YuaJ
B34_RS09375	COG3764	Sortase (surface protein transpeptidase)
B34_RS09390	COG0457	Tetratricopeptide repeat
B34_RS09395	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B34_RS09400	COG0569	domain protein
B34_RS09405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_RS09415	COG2318	DinB family
B34_RS09425	COG1454	alcohol dehydrogenase
B34_RS09430	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS09435	COG1510	regulation of RNA biosynthetic process
B34_RS09445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B34_RS09450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B34_RS09455	COG2140	Oxalate decarboxylase
B34_RS09495	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B34_RS09505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B34_RS09510	COG0726	polysaccharide deacetylase
B34_RS09515	COG1408	metallophosphoesterase
B34_RS09520	COG1968	undecaprenyl-diphosphatase activity
B34_RS09525	COG0628	permease
B34_RS09530	COG0673	inositol 2-dehydrogenase activity
B34_RS09535	COG0693	protein deglycase activity
B34_RS09540	COG0840	transmembrane signaling receptor activity
B34_RS09545	COG0840	transmembrane signaling receptor activity
B34_RS09550	COG0840	transmembrane signaling receptor activity
B34_RS09560	COG2070	2-Nitropropane dioxygenase
B34_RS09565	COG0432	Pfam Uncharacterised protein family UPF0047
B34_RS09570	COG0366	Alpha amylase catalytic
B34_RS09585	COG5297	Belongs to the glycosyl hydrolase family 6
B34_RS09590	COG1253	flavin adenine dinucleotide binding
B34_RS09595	COG2738	Putative neutral zinc metallopeptidase
B34_RS09605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B34_RS09620	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
B34_RS09630	COG0166	Belongs to the GPI family
B34_RS09635	COG1979	alcohol dehydrogenase
B34_RS09640	COG2155	Conserved Protein
B34_RS09645	COG1098	S1 RNA binding domain
B34_RS09650	COG0436	Aminotransferase
B34_RS09655	COG1522	sequence-specific DNA binding
B34_RS09660	COG2267	carboxylic ester hydrolase activity
B34_RS09690	COG5018	Exonuclease
B34_RS09695	COG2814	Major facilitator Superfamily
B34_RS09700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_RS09705	COG3011	Protein conserved in bacteria
B34_RS09715	COG3290	protein histidine kinase activity
B34_RS09720	COG4565	transcriptional regulatory protein
B34_RS09730	COG1183	phosphatidylcholine synthase activity
B34_RS09735	COG0586	Pfam SNARE associated Golgi protein
B34_RS09740	COG0688	phosphatidylethanolamine metabolic process
B34_RS09745	COG3493	citrate carrier protein
B34_RS09755	COG2111	Na H antiporter
B34_RS09755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B34_RS09760	COG2111	Na H antiporter
B34_RS09765	COG1006	Multisubunit Na H antiporter MnhC subunit
B34_RS09770	COG0651	ATP synthesis coupled electron transport
B34_RS09775	COG1863	multisubunit Na H antiporter MnhE subunit
B34_RS09780	COG2212	antiporter activity
B34_RS09785	COG1320	monovalent cation:proton antiporter activity
B34_RS09790	COG2050	protein possibly involved in aromatic compounds catabolism
B34_RS09795	COG2197	response regulator
B34_RS09800	COG4585	Histidine kinase
B34_RS09830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
B34_RS09835	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B34_RS09840	COG1335	isochorismatase
B34_RS09845	COG5506	Protein of unknown function (DUF1694)
B34_RS09860	COG0628	permease
B34_RS09865	COG1959	2 iron, 2 sulfur cluster binding
B34_RS09870	COG0657	acetylesterase activity
B34_RS09880	COG1418	mRNA catabolic process
B34_RS09885	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS09895	COG1511	domain protein
B34_RS09900	COG1674	ftsk spoiiie
B34_RS09900	COG0433	COG0433 Predicted ATPase
B34_RS09905	COG4499	WXG100 protein secretion system (Wss), protein YukC
B34_RS09910	COG5417	Belongs to the EsaB family
B34_RS09915	COG4842	Belongs to the WXG100 family
B34_RS09920	COG1115	amino acid carrier protein
B34_RS09925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B34_RS09925	COG2508	Transcriptional regulator
B34_RS09930	COG0686	Belongs to the AlaDH PNT family
B34_RS09940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B34_RS09945	COG1268	BioY protein
B34_RS09950	COG2056	Na+-H+ antiporter family
B34_RS09955	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B34_RS09960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B34_RS09965	COG3584	3D domain protein
B34_RS09975	COG1252	NADH dehydrogenase
B34_RS09980	COG0492	ferredoxin-NADP+ reductase activity
B34_RS09995	COG0456	acetyltransferase
B34_RS10000	COG0316	Belongs to the HesB IscA family
B34_RS10005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B34_RS10010	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_RS10015	COG4844	belongs to the
B34_RS10020	COG1252	NADH dehydrogenase
B34_RS10025	COG5646	InterPro IPR014922
B34_RS10035	COG0457	Tetratricopeptide repeat
B34_RS10040	COG3479	Phenolic acid decarboxylase
B34_RS10050	COG4837	Protein of unknown function (DUF1462)
B34_RS10055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B34_RS10060	COG4946	Tricorn protease homolog
B34_RS10060	COG1506	peptidase
B34_RS10060	COG0823	Involved in the tonB-independent uptake of proteins
B34_RS10065	COG0083	homoserine kinase activity
B34_RS10070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B34_RS10075	COG0460	homoserine dehydrogenase
B34_RS10085	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B34_RS10090	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B34_RS10095	COG0647	UMP catabolic process
B34_RS10100	COG2445	Protein of unknown function DUF86
B34_RS10105	COG4470	Protein conserved in bacteria
B34_RS10120	COG0739	heme binding
B34_RS10130	COG0733	neurotransmitter:sodium symporter activity
B34_RS10140	COG3377	Domain of unknown function (DUF1805)
B34_RS10145	COG0737	Belongs to the 5'-nucleotidase family
B34_RS10150	COG0730	response to heat
B34_RS10155	COG1801	Protein of unknown function DUF72
B34_RS10165	COG3226	Transcriptional regulator
B34_RS10175	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B34_RS10180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_RS10185	COG2508	Transcriptional regulator
B34_RS10190	COG2814	Major facilitator Superfamily
B34_RS10200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_RS10205	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B34_RS10210	COG2356	endonuclease I
B34_RS10220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B34_RS10235	COG0457	Tetratricopeptide repeat
B34_RS10240	COG0719	Fe-S assembly protein
B34_RS10245	COG0822	iron-sulfur transferase activity
B34_RS10250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B34_RS10255	COG0719	Fe-S assembly protein
B34_RS10260	COG0396	ATPase activity
B34_RS10270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B34_RS10275	COG1464	Belongs to the NlpA lipoprotein family
B34_RS10280	COG2011	ABC-type metal ion transport system permease component
B34_RS10285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B34_RS10295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS10300	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B34_RS10310	COG0509	glycine decarboxylation via glycine cleavage system
B34_RS10315	COG1393	Belongs to the ArsC family
B34_RS10320	COG1960	acyl-CoA dehydrogenase activity
B34_RS10325	COG0183	Belongs to the thiolase family
B34_RS10330	COG1250	3-hydroxyacyl-CoA dehydrogenase
B34_RS10330	COG1024	Enoyl-CoA hydratase
B34_RS10345	COG5577	PFAM Coat F domain
B34_RS10360	COG1120	ATPase activity
B34_RS10365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS10370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS10375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS10390	COG1686	Belongs to the peptidase S11 family
B34_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS10400	COG0783	Belongs to the Dps family
B34_RS10405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_RS10410	COG0745	RESPONSE REGULATOR receiver
B34_RS10415	COG2770	Histidine kinase
B34_RS10415	COG2205	protein histidine kinase activity
B34_RS10420	COG1309	transcriptional regulator
B34_RS10425	COG0114	fumarate hydratase activity
B34_RS10435	COG0697	spore germination
B34_RS10440	COG0814	amino acid
B34_RS10455	COG2197	response regulator
B34_RS10460	COG4585	Histidine kinase
B34_RS10465	COG4758	membrane
B34_RS10475	COG1842	Phage shock protein A
B34_RS10480	COG4758	membrane
B34_RS10485	COG4677	pectinesterase activity
B34_RS10490	COG2096	Adenosyltransferase
B34_RS10505	COG1454	alcohol dehydrogenase
B34_RS10510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_RS10515	COG1120	ATPase activity
B34_RS10520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS10525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS10530	COG1802	Transcriptional regulator
B34_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS10540	COG2258	MOSC domain
B34_RS10545	COG0583	DNA-binding transcription factor activity
B34_RS10555	COG2721	sulfolactate sulfo-lyase activity
B34_RS10560	COG0246	Mannitol dehydrogenase
B34_RS10565	COG1609	Transcriptional regulator
B34_RS10570	COG2211	Major facilitator Superfamily
B34_RS10575	COG1904	glucuronate isomerase
B34_RS10580	COG2205	protein histidine kinase activity
B34_RS10585	COG0745	RESPONSE REGULATOR receiver
B34_RS10590	COG1120	ATPase activity
B34_RS10595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS10600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS10605	COG0531	amino acid
B34_RS10615	COG1988	membrane-bound metal-dependent
B34_RS10620	COG1368	sulfuric ester hydrolase activity
B34_RS10625	COG2814	Major facilitator Superfamily
B34_RS10630	COG0656	L-ascorbic acid biosynthetic process
B34_RS10635	COG1940	carbohydrate kinase activity
B34_RS10640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B34_RS10650	COG3973	AAA domain
B34_RS10655	COG2860	membrane
B34_RS10660	COG0456	acetyltransferase
B34_RS10660	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B34_RS10665	COG0456	acetyltransferase
B34_RS10670	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B34_RS10675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B34_RS10680	COG2217	Heavy metal translocating P-type atpase
B34_RS10685	COG1653	transport
B34_RS10690	COG1175	transmembrane transport
B34_RS10695	COG0395	ABC-type sugar transport system, permease component
B34_RS10700	COG1501	Belongs to the glycosyl hydrolase 31 family
B34_RS10705	COG1472	Belongs to the glycosyl hydrolase 3 family
B34_RS10710	COG1121	(ABC) transporter
B34_RS10715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B34_RS10720	COG0803	Belongs to the bacterial solute-binding protein 9 family
B34_RS10735	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B34_RS10735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B34_RS10740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS10740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS10740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS10755	COG2217	Heavy metal translocating P-type atpase
B34_RS10760	COG2608	mercury ion transmembrane transporter activity
B34_RS10765	COG1937	Protein conserved in bacteria
B34_RS10770	COG0693	protein deglycase activity
B34_RS10775	COG1349	DNA-binding transcription factor activity
B34_RS10780	COG1070	Carbohydrate kinase
B34_RS10785	COG4952	isomerase
B34_RS10795	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS10795	COG3347	Dehydrogenase
B34_RS10800	COG2814	Major facilitator Superfamily
B34_RS10805	COG2814	Major facilitator Superfamily
B34_RS10815	COG2124	cytochrome p450
B34_RS10825	COG1846	Transcriptional regulator
B34_RS10835	COG0673	inositol 2-dehydrogenase activity
B34_RS10840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B34_RS10845	COG1054	Belongs to the UPF0176 family
B34_RS10855	COG1191	sigma factor activity
B34_RS10865	COG2140	Oxalate decarboxylase
B34_RS10940	COG5444	nuclease activity
B34_RS10985	COG1705	Flagellar rod assembly protein muramidase FlgJ
B34_RS10995	COG5280	Phage tail tape measure protein TP901
B34_RS10995	COG3953	SLT domain
B34_RS11055	COG1802	Transcriptional regulator
B34_RS11055	COG4626	Terminase
B34_RS11205	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B34_RS11210	COG0557	exoribonuclease II activity
B34_RS11215	COG1647	Serine aminopeptidase, S33
B34_RS11220	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B34_RS11225	COG2002	toxin-antitoxin pair type II binding
B34_RS11230	COG1476	TRANSCRIPTIONal
B34_RS11235	COG1396	sequence-specific DNA binding
B34_RS11240	COG1396	sequence-specific DNA binding
B34_RS11245	COG1174	glycine betaine transport
B34_RS11250	COG1732	Glycine betaine
B34_RS11255	COG1174	glycine betaine transport
B34_RS11260	COG1125	glycine betaine transport
B34_RS11260	COG0517	IMP dehydrogenase activity
B34_RS11265	COG1510	regulation of RNA biosynthetic process
B34_RS11275	COG3064	Membrane
B34_RS11285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS11295	COG0693	protein deglycase activity
B34_RS11300	COG0148	phosphopyruvate hydratase activity
B34_RS11305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B34_RS11310	COG0149	triose-phosphate isomerase activity
B34_RS11315	COG0126	phosphoglycerate kinase activity
B34_RS11320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B34_RS11325	COG2390	Transcriptional regulator
B34_RS11330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_RS11335	COG1113	amino acid transport
B34_RS11355	COG1556	Lactate utilization protein
B34_RS11360	COG1139	Iron-sulfur cluster binding protein
B34_RS11365	COG0247	lactate metabolic process
B34_RS11370	COG2186	Transcriptional regulator
B34_RS11375	COG1620	l-lactate permease
B34_RS11380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B34_RS11390	COG5039	Polysaccharide pyruvyl transferase
B34_RS11395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_RS11400	COG0110	maltose O-acetyltransferase activity
B34_RS11405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B34_RS11410	COG2244	polysaccharide biosynthetic process
B34_RS11415	COG1216	Glycosyl transferase, family 2
B34_RS11420	COG5039	Polysaccharide pyruvyl transferase
B34_RS11425	COG1216	Glycosyl transferase, family 2
B34_RS11435	COG0438	transferase activity, transferring glycosyl groups
B34_RS11440	COG1215	transferase activity, transferring glycosyl groups
B34_RS11445	COG0438	transferase activity, transferring glycosyl groups
B34_RS11450	COG1086	Polysaccharide biosynthesis protein
B34_RS11455	COG0489	protein tyrosine kinase activity
B34_RS11460	COG3944	biosynthesis protein
B34_RS11465	COG1396	sequence-specific DNA binding
B34_RS11470	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_RS11480	COG2271	Major facilitator Superfamily
B34_RS11490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B34_RS11505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_RS11515	COG1733	regulation of RNA biosynthetic process
B34_RS11520	COG1902	pentaerythritol trinitrate reductase activity
B34_RS11525	COG1621	beta-fructofuranosidase activity
B34_RS11530	COG1621	beta-fructofuranosidase activity
B34_RS11545	COG0740	serine-type endopeptidase activity
B34_RS11550	COG1611	Belongs to the LOG family
B34_RS11555	COG1694	Mazg nucleotide pyrophosphohydrolase
B34_RS11560	COG1078	dGTPase activity
B34_RS11565	COG0659	secondary active sulfate transmembrane transporter activity
B34_RS11570	COG0288	reversible hydration of carbon dioxide
B34_RS11575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_RS11580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B34_RS11585	COG0640	Transcriptional regulator
B34_RS11595	COG2732	(Barnase) inhibitor
B34_RS11600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B34_RS11605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS11610	COG1481	regulation of sporulation
B34_RS11615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B34_RS11620	COG1660	Displays ATPase and GTPase activities
B34_RS11625	COG1051	belongs to the nudix hydrolase family
B34_RS11635	COG0492	ferredoxin-NADP+ reductase activity
B34_RS11640	COG0457	Tetratricopeptide repeat
B34_RS11650	COG0140	phosphoribosyl-ATP diphosphatase activity
B34_RS11650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B34_RS11655	COG0107	imidazoleglycerol-phosphate synthase activity
B34_RS11660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B34_RS11665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B34_RS11670	COG0131	Imidazoleglycerol-phosphate dehydratase
B34_RS11675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B34_RS11680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B34_RS11685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B34_RS11690	COG4990	cell redox homeostasis
B34_RS11695	COG5297	Belongs to the glycosyl hydrolase family 6
B34_RS11700	COG0110	maltose O-acetyltransferase activity
B34_RS11705	COG0546	phosphoglycolate phosphatase activity
B34_RS11710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B34_RS11715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B34_RS11720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B34_RS11725	COG1846	Transcriptional regulator
B34_RS11730	COG2814	Major facilitator Superfamily
B34_RS11735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B34_RS11740	COG1950	PFAM Membrane protein of
B34_RS11745	COG1983	PspC domain protein
B34_RS11750	COG3595	metallopeptidase activity
B34_RS11775	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B34_RS11780	COG0556	nucleotide-excision repair
B34_RS11785	COG4897	Protein conserved in bacteria
B34_RS11795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_RS11805	COG0793	Belongs to the peptidase S41A family
B34_RS11805	COG3409	Peptidoglycan-binding domain 1 protein
B34_RS11810	COG0473	3-isopropylmalate dehydrogenase activity
B34_RS11815	COG3883	PFAM NLP P60 protein
B34_RS11815	COG0791	NLP P60 protein
B34_RS11820	COG2177	Part of the ABC transporter FtsEX involved in
B34_RS11825	COG2884	Cell division ATP-binding protein ftsE
B34_RS11835	COG2010	Cytochrome c
B34_RS11840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS11845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B34_RS11850	COG0653	protein targeting
B34_RS11855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B34_RS11870	COG1516	flagellar protein fliS
B34_RS11875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B34_RS11880	COG1334	flagellar protein FlaG
B34_RS11885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B34_RS11890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
B34_RS11895	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
B34_RS11905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B34_RS11910	COG4786	Flagellar basal body rod
B34_RS11910	COG1256	bacterial-type flagellum assembly
B34_RS11915	COG3418	PFAM FlgN family protein
B34_RS11920	COG2747	anti-sigma28 factor FlgM
B34_RS11930	COG1040	competence protein
B34_RS11940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B34_RS11945	COG1307	EDD domain protein, DegV family
B34_RS11950	COG2197	response regulator
B34_RS11955	COG4585	Histidine kinase
B34_RS11960	COG1739	Uncharacterized protein family UPF0029
B34_RS11965	COG1316	TRANSCRIPTIONal
B34_RS11975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B34_RS11980	COG0438	transferase activity, transferring glycosyl groups
B34_RS11985	COG1215	transferase activity, transferring glycosyl groups
B34_RS11990	COG3206	protein involved in exopolysaccharide biosynthesis
B34_RS11995	COG3307	-O-antigen
B34_RS12000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_RS12005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B34_RS12010	COG0438	transferase activity, transferring glycosyl groups
B34_RS12010	COG0297	glycogen (starch) synthase activity
B34_RS12015	COG2244	polysaccharide biosynthetic process
B34_RS12025	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS12025	COG2247	cell wall binding repeat
B34_RS12030	COG2385	sporulation resulting in formation of a cellular spore
B34_RS12030	COG2247	cell wall binding repeat
B34_RS12040	COG1316	TRANSCRIPTIONal
B34_RS12045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B34_RS12050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B34_RS12055	COG1134	teichoic acid transport
B34_RS12060	COG1682	transport, permease protein
B34_RS12065	COG0438	transferase activity, transferring glycosyl groups
B34_RS12075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_RS12100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_RS12100	COG0463	Glycosyl transferase, family 2
B34_RS12105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_RS12110	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B34_RS12115	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
B34_RS12120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B34_RS12125	COG4193	domain, Protein
B34_RS12130	COG1482	cell wall glycoprotein biosynthetic process
B34_RS12150	COG0800	Aldolase
B34_RS12155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_RS12160	COG1609	Transcriptional regulator
B34_RS12165	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B34_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS12175	COG1063	alcohol dehydrogenase
B34_RS12180	COG2814	Major facilitator Superfamily
B34_RS12185	COG1316	TRANSCRIPTIONal
B34_RS12190	COG0561	phosphatase activity
B34_RS12195	COG0791	NLP P60 protein
B34_RS12210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B34_RS12215	COG1609	Transcriptional regulator
B34_RS12220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_RS12225	COG1869	D-ribose catabolic process
B34_RS12230	COG1129	ABC transporter
B34_RS12235	COG1172	Belongs to the binding-protein-dependent transport system permease family
B34_RS12240	COG1879	ABC-type sugar transport system periplasmic component
B34_RS12250	COG3527	Alpha-acetolactate decarboxylase
B34_RS12255	COG0028	Belongs to the TPP enzyme family
B34_RS12260	COG0583	DNA-binding transcription factor activity
B34_RS12270	COG0405	Gamma-glutamyltransferase
B34_RS12275	COG1522	sequence-specific DNA binding
B34_RS12280	COG2059	Chromate
B34_RS12285	COG2059	Chromate
B34_RS12290	COG4464	protein tyrosine phosphatase activity
B34_RS12295	COG3944	biosynthesis protein
B34_RS12300	COG4715	Zinc finger, swim domain protein
B34_RS12305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B34_RS12310	COG0561	phosphatase activity
B34_RS12315	COG1349	DNA-binding transcription factor activity
B34_RS12325	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS12335	COG3732	PTS system glucitol sorbitol-specific
B34_RS12355	COG0629	single-stranded DNA binding
B34_RS12370	COG1970	mechanosensitive ion channel activity
B34_RS12375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B34_RS12380	COG4786	Flagellar basal body rod
B34_RS12385	COG4786	Flagellar basal body rod
B34_RS12390	COG1077	Cell shape determining protein MreB Mrl
B34_RS12395	COG1609	Transcriptional regulator
B34_RS12405	COG1846	Transcriptional regulator
B34_RS12410	COG2814	Major facilitator Superfamily
B34_RS12415	COG0671	phosphoesterase, PA-phosphatase related
B34_RS12420	COG1227	inorganic diphosphatase activity
B34_RS12425	COG3546	catalase activity
B34_RS12430	COG3361	conserved protein (COG2071)
B34_RS12435	COG0517	IMP dehydrogenase activity
B34_RS12440	COG0598	Magnesium transport protein CorA
B34_RS12445	COG1253	flavin adenine dinucleotide binding
B34_RS12450	COG0004	ammonium transporteR
B34_RS12455	COG0347	Belongs to the P(II) protein family
B34_RS12460	COG0740	serine-type endopeptidase activity
B34_RS12470	COG0739	heme binding
B34_RS12475	COG1247	-acetyltransferase
B34_RS12485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_RS12490	COG0477	Major facilitator Superfamily
B34_RS12495	COG3251	PFAM MbtH domain protein
B34_RS12500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_RS12505	COG3433	isochorismatase activity
B34_RS12505	COG1535	isochorismatase
B34_RS12510	COG1021	2,3-dihydroxybenzoate-AMP ligase
B34_RS12515	COG1169	isochorismate synthase
B34_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS12525	COG2819	hydrolase of the alpha beta superfamily
B34_RS12530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS12535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS12540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS12545	COG2207	Transcriptional regulator
B34_RS12545	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS12555	COG2910	NAD(P)H-binding
B34_RS12560	COG1959	2 iron, 2 sulfur cluster binding
B34_RS12565	COG1994	Peptidase M50
B34_RS12570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B34_RS12575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B34_RS12585	COG3383	formate dehydrogenase (NAD+) activity
B34_RS12590	COG2304	oxidoreductase activity
B34_RS12595	COG2304	oxidoreductase activity
B34_RS12600	COG2385	sporulation resulting in formation of a cellular spore
B34_RS12605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B34_RS12615	COG4836	Membrane
B34_RS12620	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B34_RS12625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B34_RS12630	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B34_RS12635	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B34_RS12640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B34_RS12645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B34_RS12650	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B34_RS12670	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B34_RS12675	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B34_RS12680	COG4475	Protein of unknown function (DUF436)
B34_RS12685	COG0698	ribose 5-phosphate isomerase
B34_RS12690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_RS12695	COG1971	Probably functions as a manganese efflux pump
B34_RS12700	COG0009	L-threonylcarbamoyladenylate synthase
B34_RS12705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B34_RS12715	COG0738	Major facilitator superfamily
B34_RS12720	COG0673	inositol 2-dehydrogenase activity
B34_RS12725	COG0561	phosphatase activity
B34_RS12730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_RS12735	COG1609	Transcriptional regulator
B34_RS12740	COG2890	protein-(glutamine-N5) methyltransferase activity
B34_RS12745	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B34_RS12750	COG0346	lactoylglutathione lyase activity
B34_RS12755	COG0789	Transcriptional regulator
B34_RS12760	COG0679	Auxin Efflux Carrier
B34_RS12765	COG0281	malic enzyme
B34_RS12770	COG1435	thymidine kinase activity
B34_RS12775	COG0254	rRNA binding
B34_RS12780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B34_RS12785	COG1494	fructose-1,6-bisphosphatase
B34_RS12790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B34_RS12795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B34_RS12800	COG0191	fructose-bisphosphate aldolase activity
B34_RS12805	COG2204	response regulator
B34_RS12810	COG4821	SIS domain
B34_RS12820	COG0504	CTP synthase activity
B34_RS12825	COG3343	RNA polymerase activity
B34_RS12830	COG1960	acyl-CoA dehydrogenase activity
B34_RS12835	COG1960	acyl-CoA dehydrogenase activity
B34_RS12840	COG1250	3-hydroxyacyl-CoA dehydrogenase
B34_RS12845	COG0183	Belongs to the thiolase family
B34_RS12850	COG2181	nitrate reductase activity
B34_RS12850	COG0247	lactate metabolic process
B34_RS12855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B34_RS12865	COG0018	arginyl-trna synthetase
B34_RS12870	COG4506	Protein conserved in bacteria
B34_RS12875	COG0010	Belongs to the arginase family
B34_RS12880	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B34_RS12895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_RS12905	COG1994	Peptidase M50
B34_RS12910	COG1942	4-Oxalocrotonate Tautomerase
B34_RS12920	COG3465	dGTPase activity
B34_RS12925	COG1078	dGTPase activity
B34_RS12930	COG4844	belongs to the
B34_RS12955	COG2814	Major facilitator Superfamily
B34_RS12980	COG1414	Transcriptional regulator
B34_RS12990	COG0280	phosphate acetyltransferase
B34_RS12995	COG3253	May function as heme-dependent peroxidase
B34_RS13010	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_RS13030	COG1131	(ABC) transporter
B34_RS13045	COG2363	Small membrane protein
B34_RS13050	COG2233	PERMEase
B34_RS13060	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS13065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B34_RS13070	COG1216	Glycosyl transferase, family 2
B34_RS13075	COG0351	phosphomethylpyrimidine kinase
B34_RS13085	COG1621	beta-fructofuranosidase activity
B34_RS13090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS13090	COG1263	PTS System
B34_RS13095	COG3711	transcriptional antiterminator
B34_RS13105	COG1404	Belongs to the peptidase S8 family
B34_RS13115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_RS13120	COG0778	Nitroreductase
B34_RS13125	COG1473	amidohydrolase
B34_RS13130	COG0772	Belongs to the SEDS family
B34_RS13135	COG0772	Belongs to the SEDS family
B34_RS13140	COG3314	Sporulation integral membrane protein YlbJ
B34_RS13160	COG0456	acetyltransferase
B34_RS13195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B34_RS13205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B34_RS13210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B34_RS13215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_RS13235	COG3162	membrane
B34_RS13240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS13245	COG1070	Carbohydrate kinase
B34_RS13250	COG2115	Belongs to the xylose isomerase family
B34_RS13260	COG0352	thiamine-phosphate diphosphorylase activity
B34_RS13265	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B34_RS13270	COG0583	DNA-binding transcription factor activity
B34_RS13285	COG1380	Effector of murein hydrolase LrgA
B34_RS13290	COG1346	cytolysis
B34_RS13300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS13305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B34_RS13310	COG0346	lactoylglutathione lyase activity
B34_RS13315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B34_RS13320	COG1442	glycosyl transferase family 8
B34_RS13325	COG4585	Histidine kinase
B34_RS13330	COG2197	response regulator
B34_RS13335	COG2409	Drug exporters of the RND superfamily
B34_RS13340	COG5522	Integral membrane protein (intg_mem_TP0381)
B34_RS13345	COG2271	Major facilitator Superfamily
B34_RS13350	COG4948	Mandelate Racemase Muconate Lactonizing
B34_RS13355	COG0800	Aldolase
B34_RS13360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_RS13370	COG2234	aminopeptidase activity
B34_RS13375	COG0477	Major facilitator Superfamily
B34_RS13385	COG2357	RelA SpoT domain protein
B34_RS13400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_RS13405	COG1696	Membrane protein involved in D-alanine export
B34_RS13410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B34_RS13415	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B34_RS13420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_RS13425	COG2814	Major facilitator Superfamily
B34_RS13430	COG1486	melibiose metabolic process
B34_RS13435	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_RS13440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS13445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS13450	COG3711	transcriptional antiterminator
B34_RS13450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS13455	COG2094	Belongs to the DNA glycosylase MPG family
B34_RS13465	COG0372	Belongs to the citrate synthase family
B34_RS13470	COG2079	MmgE PrpD family protein
B34_RS13475	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B34_RS13490	COG1132	(ABC) transporter
B34_RS13495	COG2755	lipolytic protein G-D-S-L family
B34_RS13510	COG2814	Major facilitator Superfamily
B34_RS13515	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_RS13520	COG1131	(ABC) transporter
B34_RS13540	COG1595	DNA-templated transcription, initiation
B34_RS13545	COG2814	Major facilitator Superfamily
B34_RS13550	COG0753	catalase activity
B34_RS13555	COG0753	catalase activity
B34_RS13560	COG0735	belongs to the Fur family
B34_RS13565	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B34_RS13570	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_RS13575	COG1131	(ABC) transporter
B34_RS13590	COG1131	(ABC) transporter
B34_RS13645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B34_RS13650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B34_RS13655	COG4988	ABC transporter
B34_RS13660	COG1294	oxidase, subunit
B34_RS13665	COG1271	oxidase subunit
B34_RS13675	COG2116	formate transmembrane transporter activity
B34_RS13685	COG0281	malic enzyme
B34_RS13690	COG1757	Na H antiporter
B34_RS13695	COG1027	Aspartate ammonia-lyase
B34_RS13700	COG0252	asparaginase activity
B34_RS13705	COG1396	sequence-specific DNA binding
B34_RS13710	COG2706	6-phosphogluconolactonase activity
B34_RS13715	COG0745	RESPONSE REGULATOR receiver
B34_RS13720	COG2205	protein histidine kinase activity
B34_RS13730	COG1136	(ABC) transporter
B34_RS13735	COG0577	efflux transmembrane transporter activity
B34_RS13740	COG5294	Protein conserved in bacteria
B34_RS13750	COG0726	polysaccharide deacetylase
B34_RS13760	COG1215	transferase activity, transferring glycosyl groups
B34_RS13765	COG3493	citrate carrier protein
B34_RS13770	COG0584	glycerophosphoryl diester phosphodiesterase
B34_RS13785	COG1368	sulfuric ester hydrolase activity
B34_RS13795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS13810	COG2235	arginine
B34_RS13815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B34_RS13825	COG0549	Belongs to the carbamate kinase family
B34_RS13835	COG2723	6-phospho-beta-galactosidase activity
B34_RS13840	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS13850	COG1595	DNA-templated transcription, initiation
B34_RS13875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B34_RS13880	COG2195	Cleaves the N-terminal amino acid of tripeptides
B34_RS13890	COG1621	beta-fructofuranosidase activity
B34_RS13895	COG2223	nitrite transmembrane transporter activity
B34_RS13900	COG0395	ABC-type sugar transport system, permease component
B34_RS13905	COG1175	transmembrane transport
B34_RS13915	COG1609	Transcriptional regulator
B34_RS13930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B34_RS13935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B34_RS13940	COG0463	Glycosyl transferase, family 2
B34_RS13945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_RS13955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_RS13960	COG0693	protein deglycase activity
B34_RS13960	COG0753	catalase activity
B34_RS13970	COG2723	6-phospho-beta-galactosidase activity
B34_RS13975	COG1263	PTS System
B34_RS13975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS13975	COG2190	(PTS) system
B34_RS13980	COG3711	transcriptional antiterminator
B34_RS13985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B34_RS13990	COG1122	ATPase activity
B34_RS13995	COG4721	ABC-type cobalt transport system, permease component
B34_RS14000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B34_RS14005	COG2224	Isocitrate lyase
B34_RS14010	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B34_RS14020	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
B34_RS14025	COG0577	efflux transmembrane transporter activity
B34_RS14030	COG1136	(ABC) transporter
B34_RS14035	COG2205	protein histidine kinase activity
B34_RS14040	COG0745	RESPONSE REGULATOR receiver
B34_RS14045	COG2723	6-phospho-beta-galactosidase activity
B34_RS14050	COG1263	PTS System
B34_RS14050	COG2190	(PTS) system
B34_RS14050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS14060	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
B34_RS14075	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_RS14080	COG0513	Belongs to the DEAD box helicase family
B34_RS14110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B34_RS14115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B34_RS14120	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B34_RS14125	COG2390	Transcriptional regulator
B34_RS14135	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B34_RS14140	COG3706	GGDEF domain
B34_RS14145	COG5298	Protein conserved in bacteria
B34_RS14160	COG3977	Valine--pyruvate aminotransferase
B34_RS14175	COG1181	Belongs to the D-alanine--D-alanine ligase family
B34_RS14185	COG0191	fructose-bisphosphate aldolase activity
B34_RS14190	COG1082	Xylose isomerase domain protein TIM barrel
B34_RS14195	COG1082	Xylose isomerase domain protein TIM barrel
B34_RS14200	COG0673	inositol 2-dehydrogenase activity
B34_RS14205	COG2814	Major facilitator Superfamily
B34_RS14210	COG1082	Xylose isomerase domain protein TIM barrel
B34_RS14215	COG3962	Belongs to the TPP enzyme family
B34_RS14220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B34_RS14225	COG3718	enzyme involved in inositol metabolism
B34_RS14230	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS14235	COG1349	DNA-binding transcription factor activity
B34_RS14240	COG0667	Aldo Keto reductase
B34_RS14245	COG0584	glycerophosphoryl diester phosphodiesterase
B34_RS14250	COG2271	Major facilitator Superfamily
B34_RS14255	COG0326	Molecular chaperone. Has ATPase activity
B34_RS14260	COG0488	(ABC) transporter
B34_RS14265	COG0561	phosphatase activity
B34_RS14285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B34_RS14315	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
B34_RS14320	COG0577	efflux transmembrane transporter activity
B34_RS14325	COG1136	(ABC) transporter
B34_RS14330	COG2205	protein histidine kinase activity
B34_RS14335	COG0745	RESPONSE REGULATOR receiver
B34_RS14345	COG0840	transmembrane signaling receptor activity
B34_RS14345	COG5278	phosphoserine phosphatase activity
B34_RS14350	COG1115	amino acid carrier protein
B34_RS14355	COG0686	Belongs to the AlaDH PNT family
B34_RS14360	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B34_RS14365	COG1874	Beta-galactosidase
B34_RS14370	COG3833	ABC-type maltose transport systems, permease component
B34_RS14375	COG1175	transmembrane transport
B34_RS14380	COG2182	Extracellular solute-binding protein
B34_RS14385	COG1609	Transcriptional regulator
B34_RS14395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_RS14400	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B34_RS14405	COG1940	carbohydrate kinase activity
B34_RS14430	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS14430	COG1454	alcohol dehydrogenase
B34_RS14435	COG0450	alkyl hydroperoxide reductase
B34_RS14440	COG3634	alkyl hydroperoxide reductase activity
B34_RS14465	COG1131	(ABC) transporter
B34_RS14470	COG0842	Transport permease protein
B34_RS14480	COG2197	response regulator
B34_RS14505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B34_RS14520	COG0456	acetyltransferase
B34_RS14535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_RS14540	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B34_RS14545	COG4853	Protein conserved in bacteria
B34_RS14550	COG4863	YycH protein
B34_RS14555	COG5002	protein histidine kinase activity
B34_RS14560	COG0745	RESPONSE REGULATOR receiver
B34_RS14585	COG1051	belongs to the nudix hydrolase family
B34_RS14590	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B34_RS14600	COG0305	Participates in initiation and elongation during chromosome replication
B34_RS14615	COG3093	addiction module antidote protein HigA
B34_RS14620	COG2807	transmembrane transport
B34_RS14625	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B34_RS14630	COG0363	glucosamine-6-phosphate deaminase activity
B34_RS14635	COG2188	Transcriptional regulator
B34_RS14640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B34_RS14645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS14645	COG1263	PTS System
B34_RS14650	COG0359	binds to the 23S rRNA
B34_RS14655	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B34_RS14660	COG4241	membrane
B34_RS14665	COG5577	PFAM Coat F domain
B34_RS14670	COG0589	response to stress
B34_RS14675	COG0659	secondary active sulfate transmembrane transporter activity
B34_RS14680	COG2271	Major facilitator Superfamily
B34_RS14685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B34_RS14690	COG0629	single-stranded DNA binding
B34_RS14695	COG0360	Binds together with S18 to 16S ribosomal RNA
B34_RS14700	COG0012	GTP binding
B34_RS14710	COG4481	Protein conserved in bacteria
B34_RS14715	COG3949	Membrane
B34_RS14725	COG1475	DNA binding
B34_RS14730	COG1192	Involved in chromosome partitioning
B34_RS14735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B34_RS14745	COG1475	DNA binding
B34_RS14750	COG0357	Ribosomal RNA small subunit methyltransferase G
B34_RS14755	COG0445	tRNA wobble uridine modification
B34_RS14760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B34_RS14765	COG1847	R3H domain protein
B34_RS14770	COG0706	membrane insertase activity
B34_RS14775	COG0594	ribonuclease P activity
B34_RS14785	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B34_RS14790	COG0592	DNA-directed DNA polymerase activity
B34_RS14795	COG2501	S4 domain
B34_RS14800	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B34_RS14810	COG0187	DNA topoisomerase II activity
B34_RS14815	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B34_RS14850	COG0516	GMP reductase activity
B34_RS14850	COG0517	IMP dehydrogenase activity
B34_RS14855	COG1686	Belongs to the peptidase S11 family
B34_RS14860	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B34_RS14865	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B34_RS14870	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B34_RS14875	COG1929	Belongs to the glycerate kinase type-1 family
B34_RS14880	COG2610	gluconate transmembrane transporter activity
B34_RS14885	COG3835	regulator
B34_RS14900	COG1428	Deoxynucleoside kinase
B34_RS14905	COG1428	Deoxynucleoside kinase
B34_RS14910	COG1388	LysM domain
B34_RS14910	COG3858	chitin binding
B34_RS14915	COG1335	isochorismatase
B34_RS14920	COG0590	tRNA wobble adenosine to inosine editing
B34_RS14930	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B34_RS14935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B34_RS14940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B34_RS14985	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B34_RS14990	COG3853	Toxic anion resistance protein (TelA)
B34_RS14995	COG1982	Orn Lys Arg decarboxylase major
B34_RS15000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B34_RS15005	COG3870	Protein conserved in bacteria
B34_RS15010	COG1728	Protein conserved in bacteria
B34_RS15015	COG0470	DNA polymerase III
B34_RS15020	COG1774	PSP1 C-terminal conserved region
B34_RS15025	COG4467	Involved in initiation control of chromosome replication
B34_RS15030	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B34_RS15035	COG2827	Endonuclease containing a URI domain
B34_RS15040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B34_RS15045	COG2002	toxin-antitoxin pair type II binding
B34_RS15050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_RS15050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B34_RS15055	COG0084	hydrolase, TatD family'
B34_RS15060	COG3584	3D domain protein
B34_RS15060	COG3583	domain protein
B34_RS15065	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B34_RS15070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B34_RS15080	COG4466	Protein conserved in bacteria
B34_RS15090	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B34_RS15095	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B34_RS15100	COG0251	oxidation-reduction process
B34_RS15105	COG2088	sporulation resulting in formation of a cellular spore
B34_RS15110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B34_RS15115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B34_RS15120	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B34_RS15125	COG0193	aminoacyl-tRNA hydrolase activity
B34_RS15135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B34_RS15140	COG2002	toxin-antitoxin pair type II binding
B34_RS15145	COG2244	polysaccharide biosynthetic process
B34_RS15150	COG3956	TIGRFAM MazG family protein
B34_RS15155	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B34_RS15170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B34_RS15175	COG1098	S1 RNA binding domain
B34_RS15190	COG2208	phosphoserine phosphatase activity
B34_RS15195	COG2304	oxidoreductase activity
B34_RS15200	COG0515	serine threonine protein kinase
B34_RS15205	COG0037	tRNA processing
B34_RS15210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B34_RS15215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B34_RS15220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B34_RS15225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B34_RS15230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B34_RS15235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B34_RS15245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B34_RS15250	COG0512	Glutamine amidotransferase of anthranilate synthase
B34_RS15255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B34_RS15260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B34_RS15265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B34_RS15270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B34_RS15275	COG1396	sequence-specific DNA binding
B34_RS15280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B34_RS15285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B34_RS15365	COG4463	regulation of RNA biosynthetic process
B34_RS15370	COG3880	PFAM UvrB UvrC protein
B34_RS15375	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B34_RS15380	COG0542	response to heat
B34_RS15385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B34_RS15390	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B34_RS15395	COG4956	integral membrane protein (PIN domain superfamily)
B34_RS15400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B34_RS15405	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B34_RS15410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B34_RS15415	COG1045	serine acetyltransferase
B34_RS15420	COG0215	cysteine-tRNA ligase activity
B34_RS15425	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B34_RS15430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B34_RS15435	COG3688	RNA-binding protein containing a PIN domain
B34_RS15445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B34_RS15455	COG0250	Participates in transcription elongation, termination and antitermination
B34_RS15460	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B34_RS15465	COG0081	regulation of translation
B34_RS15470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B34_RS15475	COG0222	ribosome binding
B34_RS15480	COG2813	Specifically methylates the guanine in position
B34_RS15485	COG0085	RNA polymerase activity
B34_RS15490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B34_RS15495	COG1358	cellular component organization or biogenesis
B34_RS15500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B34_RS15505	COG0049	tRNA binding
B34_RS15510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B34_RS15515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B34_RS15525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B34_RS15530	COG0088	Forms part of the polypeptide exit tunnel
B34_RS15535	COG0089	rRNA binding
B34_RS15540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B34_RS15545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B34_RS15550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B34_RS15555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B34_RS15560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B34_RS15565	COG0255	Belongs to the universal ribosomal protein uL29 family
B34_RS15570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B34_RS15575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B34_RS15580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B34_RS15585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B34_RS15590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_RS15595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B34_RS15600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B34_RS15605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B34_RS15610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B34_RS15615	COG1841	ribosomal large subunit assembly
B34_RS15620	COG0200	Binds to the 23S rRNA
B34_RS15625	COG0201	protein transport
B34_RS15630	COG0563	adenylate kinase activity
B34_RS15635	COG0024	Methionine aminopeptidase
B34_RS15640	COG2163	COG2163 Ribosomal protein L14E L6E L27E
B34_RS15645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B34_RS15650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B34_RS15655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B34_RS15660	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B34_RS15665	COG0202	RNA polymerase activity
B34_RS15670	COG0203	ribosomal protein L17
B34_RS15675	COG1122	ATPase activity
B34_RS15680	COG1122	ATPase activity
B34_RS15685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B34_RS15690	COG0101	tRNA pseudouridine synthase activity
B34_RS15695	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B34_RS15700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B34_RS15705	COG2318	DinB family
B34_RS15725	COG1131	(ABC) transporter
B34_RS15755	COG2274	protein secretion by the type I secretion system
B34_RS15780	COG3290	protein histidine kinase activity
B34_RS15805	COG0860	N-Acetylmuramoyl-L-alanine amidase
B34_RS15810	COG0489	protein tyrosine kinase activity
B34_RS15820	COG2194	sulfuric ester hydrolase activity
B34_RS15825	COG0726	polysaccharide deacetylase
B34_RS15855	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_RS15865	COG0385	Bile acid
B34_RS15880	COG3876	Protein conserved in bacteria
B34_RS15885	COG1472	Belongs to the glycosyl hydrolase 3 family
B34_RS15890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_RS15895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS15895	COG1263	PTS System
B34_RS15900	COG1737	Transcriptional regulator
B34_RS15905	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
B34_RS15910	COG1683	Conserved Protein
B34_RS15945	COG1595	DNA-templated transcription, initiation
B34_RS15950	COG5662	AntiSigma factor
B34_RS15955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B34_RS15960	COG4856	YbbR-like protein
B34_RS15965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B34_RS15970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B34_RS15990	COG1725	Transcriptional regulator
B34_RS15995	COG0640	Transcriptional regulator
B34_RS16000	COG2814	Major facilitator Superfamily
B34_RS16010	COG1132	(ABC) transporter
B34_RS16015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B34_RS16040	COG1011	Hydrolase
B34_RS16045	COG1113	amino acid transport
B34_RS16050	COG2851	Citrate transporter
B34_RS16055	COG3181	Tripartite tricarboxylate transporter family receptor
B34_RS16060	COG4565	transcriptional regulatory protein
B34_RS16065	COG3290	protein histidine kinase activity
B34_RS16080	COG2211	Major facilitator Superfamily
B34_RS16100	COG1331	Highly conserved protein containing a thioredoxin domain
B34_RS16110	COG0477	Major facilitator Superfamily
B34_RS16130	COG1283	sodium-dependent phosphate transmembrane transporter activity
B34_RS16135	COG4682	membrane
B34_RS16160	COG0697	spore germination
B34_RS16165	COG2207	Transcriptional regulator
B34_RS16165	COG1917	Cupin 2, conserved barrel domain protein
B34_RS16185	COG0371	Dehydrogenase
B34_RS16190	COG0840	transmembrane signaling receptor activity
B34_RS16195	COG4213	ABC transporter substrate-binding protein
B34_RS16210	COG4257	antibiotic catabolic process
B34_RS16220	COG0833	amino acid
B34_RS16225	COG2040	homocysteine
B34_RS16235	COG1263	PTS System
B34_RS16235	COG2190	(PTS) system
B34_RS16235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS16240	COG0789	Transcriptional regulator
B34_RS16245	COG2323	membrane
B34_RS16250	COG4451	ribulose bisphosphate carboxylase, small
B34_RS16250	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B34_RS16260	COG2205	protein histidine kinase activity
B34_RS16265	COG1115	amino acid carrier protein
B34_RS16270	COG2066	Belongs to the glutaminase family
B34_RS16275	COG4191	Histidine kinase
B34_RS16280	COG0784	Response regulator, receiver
B34_RS16305	COG3540	Alkaline phosphatase
B34_RS16310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B34_RS16315	COG0805	protein transport
B34_RS16320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B34_RS16325	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS16330	COG2271	Major facilitator Superfamily
B34_RS16335	COG4948	Mandelate Racemase Muconate Lactonizing
B34_RS16340	COG2186	Transcriptional regulator
B34_RS16345	COG2721	sulfolactate sulfo-lyase activity
B34_RS16350	COG0745	RESPONSE REGULATOR receiver
B34_RS16355	COG2205	protein histidine kinase activity
B34_RS16360	COG1131	(ABC) transporter
B34_RS16385	COG3173	Aminoglycoside phosphotransferase
B34_RS16390	COG1846	Transcriptional regulator
B34_RS16395	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS16415	COG0789	Transcriptional regulator
B34_RS16440	COG0697	spore germination
B34_RS16445	COG1714	RDD family
B34_RS16450	COG1405	negative regulation of cell septum assembly
B34_RS16450	COG3012	SEC-C Motif Domain Protein
B34_RS16455	COG1131	(ABC) transporter
B34_RS16480	COG0583	DNA-binding transcription factor activity
B34_RS16485	COG1942	4-Oxalocrotonate Tautomerase
B34_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS16505	COG1288	antiporter activity
B34_RS16515	COG0456	acetyltransferase
B34_RS16525	COG1164	Oligoendopeptidase f
B34_RS16530	COG2261	transglycosylase associated protein
B34_RS16540	COG0247	lactate metabolic process
B34_RS16545	COG0277	FAD linked oxidase domain protein
B34_RS16550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS16555	COG1447	Phosphotransferase system cellobiose-specific component IIA
B34_RS16560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B34_RS16565	COG1486	melibiose metabolic process
B34_RS16570	COG2188	Transcriptional regulator
B34_RS16575	COG3394	polysaccharide catabolic process
B34_RS16590	COG3591	Belongs to the peptidase S1B family
B34_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS16605	COG1595	DNA-templated transcription, initiation
B34_RS16615	COG3773	Cell wall hydrolase
B34_RS16620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_RS16625	COG0791	NLP P60 protein
B34_RS16625	COG3883	PFAM NLP P60 protein
B34_RS16640	COG1309	transcriptional regulator
B34_RS16660	COG2310	stress, protein
B34_RS16665	COG2310	stress, protein
B34_RS16670	COG2310	stress, protein
B34_RS16675	COG0861	Integral membrane protein TerC family
B34_RS16695	COG3853	Toxic anion resistance protein (TelA)
B34_RS16700	COG0785	Cytochrome C biogenesis protein
B34_RS16710	COG0789	Transcriptional regulator
B34_RS16715	COG2223	nitrite transmembrane transporter activity
B34_RS16720	COG0039	L-malate dehydrogenase activity
B34_RS16725	COG1620	l-lactate permease
B34_RS16730	COG1280	lysine exporter protein (LysE YggA)
B34_RS16735	COG1113	amino acid transport
B34_RS16740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B34_RS16745	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B34_RS16750	COG3541	Predicted nucleotidyltransferase
B34_RS16755	COG0506	proline dehydrogenase activity
B34_RS16760	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS16765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS16770	COG2508	Transcriptional regulator
B34_RS16775	COG3689	TIGRFAM TIGR03943 family protein
B34_RS16785	COG3458	cephalosporin-C deacetylase activity
B34_RS16805	COG0765	amino acid transport
B34_RS16810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_RS16815	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_RS16825	COG2723	6-phospho-beta-galactosidase activity
B34_RS16835	COG3209	COG3209 Rhs family protein
B34_RS16845	COG0515	serine threonine protein kinase
B34_RS16845	COG3266	domain, Protein
B34_RS16855	COG5444	nuclease activity
B34_RS16880	COG1176	ABC-type spermidine putrescine transport system, permease component I
B34_RS16885	COG1177	transmembrane transport
B34_RS16890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_RS16895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_RS16900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B34_RS16905	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B34_RS16910	COG0697	spore germination
B34_RS16915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_RS16925	COG2819	hydrolase of the alpha beta superfamily
B34_RS16930	COG3708	Transcriptional regulator
B34_RS16930	COG2207	Transcriptional regulator
B34_RS16940	COG2364	Membrane
B34_RS16950	COG1131	(ABC) transporter
B34_RS16975	COG1126	abc transporter atp-binding protein
B34_RS16980	COG0765	amino acid transport
B34_RS16985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B34_RS16990	COG3829	transcription factor binding
B34_RS16995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B34_RS17000	COG0833	amino acid
B34_RS17005	COG0010	Belongs to the arginase family
B34_RS17010	COG0583	DNA-binding transcription factor activity
B34_RS17015	COG0163	prenyltransferase activity
B34_RS17020	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
B34_RS17070	COG5444	nuclease activity
B34_RS17090	COG2972	Histidine kinase
B34_RS17095	COG2207	Transcriptional regulator
B34_RS17095	COG4753	response regulator
B34_RS17100	COG4213	ABC transporter substrate-binding protein
B34_RS17110	COG4214	carbohydrate transport
B34_RS17115	COG2271	Major facilitator Superfamily
B34_RS17120	COG0456	acetyltransferase
B34_RS17120	COG1846	Transcriptional regulator
B34_RS17125	COG1874	Beta-galactosidase
B34_RS17130	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
B34_RS17135	COG3104	oligopeptide transport
B34_RS17140	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_RS17150	COG0697	spore germination
B34_RS17160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B34_RS17170	COG1136	(ABC) transporter
B34_RS17175	COG0577	efflux transmembrane transporter activity
B34_RS17180	COG0745	RESPONSE REGULATOR receiver
B34_RS17185	COG3850	Histidine kinase
B34_RS17185	COG5002	protein histidine kinase activity
B34_RS17190	COG0840	transmembrane signaling receptor activity
B34_RS17195	COG0527	aspartate kinase activity
B34_RS17200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS17205	COG4605	iron ion homeostasis
B34_RS17210	COG4604	ABC transporter, ATP-binding protein
B34_RS17215	COG4607	ABC-type enterochelin transport system periplasmic component
B34_RS17220	COG2814	Major facilitator Superfamily
B34_RS17225	COG1309	transcriptional regulator
B34_RS17235	COG0778	Nitroreductase
B34_RS17240	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B34_RS17245	COG0640	Transcriptional regulator
B34_RS17250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_RS17255	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B34_RS17260	COG0531	amino acid
B34_RS17265	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS17270	COG0697	spore germination
B34_RS17280	COG4549	nuclear export factor GLE1
B34_RS17285	COG1276	copper resistance
B34_RS17285	COG2372	response to copper ion
B34_RS17290	COG1349	DNA-binding transcription factor activity
B34_RS17295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_RS17300	COG0243	molybdopterin cofactor binding
B34_RS17305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_RS17310	COG2146	nitrite reductase [NAD(P)H] activity
B34_RS17315	COG1587	Uroporphyrinogen-III synthase
B34_RS17315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B34_RS17320	COG1802	Transcriptional regulator
B34_RS17325	COG0471	metal ion transport
B34_RS17330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B34_RS17335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B34_RS17350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS17365	COG3959	Transketolase, thiamine diphosphate binding domain
B34_RS17370	COG3958	Transketolase
B34_RS17375	COG0561	phosphatase activity
B34_RS17380	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B34_RS17385	COG1914	H( )-stimulated, divalent metal cation uptake system
B34_RS17390	COG4336	lyase activity
B34_RS17395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B34_RS17400	COG1984	allophanate hydrolase subunit 2
B34_RS17405	COG1414	Transcriptional regulator
B34_RS17410	COG2755	lipolytic protein G-D-S-L family
B34_RS17415	COG2213	PTS system mannitol-specific
B34_RS17420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS17425	COG0246	Mannitol dehydrogenase
B34_RS17430	COG3711	transcriptional antiterminator
B34_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS17440	COG1917	Cupin 2, conserved barrel domain protein
B34_RS17450	COG3871	stress protein (general stress protein 26)
B34_RS17465	COG2814	Major facilitator Superfamily
B34_RS17475	COG1522	sequence-specific DNA binding
B34_RS17480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B34_RS17480	COG0551	DNA topoisomerase type I activity
B34_RS17485	COG0531	amino acid
B34_RS17490	COG0028	Belongs to the TPP enzyme family
B34_RS17495	COG3397	chitin binding
B34_RS17510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_RS17515	COG1914	H( )-stimulated, divalent metal cation uptake system
B34_RS17520	COG2261	transglycosylase associated protein
B34_RS17525	COG1027	Aspartate ammonia-lyase
B34_RS17530	COG1819	glycosyl
B34_RS17535	COG4876	unkown
B34_RS17540	COG2217	Heavy metal translocating P-type atpase
B34_RS17550	COG0662	Cupin 2, conserved barrel domain protein
B34_RS17555	COG3729	General stress protein
B34_RS17560	COG0628	permease
B34_RS17565	COG1301	dicarboxylic acid transport
B34_RS17570	COG1131	(ABC) transporter
B34_RS17575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_RS17585	COG1960	acyl-CoA dehydrogenase activity
B34_RS17600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS17605	COG1181	Belongs to the D-alanine--D-alanine ligase family
B34_RS17610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B34_RS17620	COG0513	Belongs to the DEAD box helicase family
B34_RS17625	COG3402	PFAM membrane-flanked domain
B34_RS17630	COG3428	Bacterial PH domain
B34_RS17635	COG0705	Rhomboid family
B34_RS17640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B34_RS17645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B34_RS17650	COG0864	Transcriptional regulator
B34_RS17655	COG2337	Toxic component of a toxin-antitoxin (TA) module
B34_RS17660	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_RS17665	COG1366	Belongs to the anti-sigma-factor antagonist family
B34_RS17670	COG2172	sigma factor antagonist activity
B34_RS17675	COG2208	phosphoserine phosphatase activity
B34_RS17685	COG2172	sigma factor antagonist activity
B34_RS17690	COG1191	sigma factor activity
B34_RS17695	COG2208	phosphoserine phosphatase activity
B34_RS17700	COG2183	response to ionizing radiation
B34_RS17705	COG1309	transcriptional regulator
B34_RS17710	COG2409	Drug exporters of the RND superfamily
B34_RS17710	COG1033	growth of symbiont in host cell
B34_RS17715	COG3091	SprT-like family
B34_RS17755	COG0582	viral genome integration into host DNA
B34_RS17760	COG2856	Zn peptidase
B34_RS17765	COG1396	sequence-specific DNA binding
B34_RS17785	COG1674	ftsk spoiiie
B34_RS17790	COG2946	Replication initiation factor
B34_RS17825	COG0433	COG0433 Predicted ATPase
B34_RS17835	COG5644	endopeptidase inhibitor activity
B34_RS17840	COG0791	NLP P60 protein
B34_RS17840	COG0741	lytic transglycosylase activity
B34_RS17860	COG0457	Tetratricopeptide repeat
B34_RS17885	COG1476	TRANSCRIPTIONal
B34_RS17890	COG3239	Fatty acid desaturase
B34_RS17895	COG1278	Cold shock
B34_RS17910	COG2364	Membrane
B34_RS17915	COG1846	Transcriptional regulator
B34_RS17920	COG0456	acetyltransferase
B34_RS17925	COG2808	Putative FMN-binding domain
B34_RS17935	COG1733	regulation of RNA biosynthetic process
B34_RS17940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS17950	COG0583	DNA-binding transcription factor activity
B34_RS17965	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B34_RS17970	COG1113	amino acid transport
B34_RS17985	COG1595	DNA-templated transcription, initiation
B34_RS17995	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B34_RS17995	COG2755	lipolytic protein G-D-S-L family
B34_RS18000	COG2814	Major facilitator Superfamily
B34_RS18005	COG0745	RESPONSE REGULATOR receiver
B34_RS18005	COG2972	Histidine kinase
B34_RS18010	COG3279	Response regulator of the LytR AlgR family
B34_RS18020	COG3764	Sortase (surface protein transpeptidase)
B34_RS18025	COG2814	Major facilitator Superfamily
B34_RS18065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B34_RS18070	COG0802	atpase or kinase
B34_RS18075	COG1214	PFAM Peptidase M22, glycoprotease
B34_RS18080	COG0456	acetyltransferase
B34_RS18085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
B34_RS18090	COG0488	(ABC) transporter
B34_RS18095	COG0315	cyclic pyranopterin monophosphate synthase activity
B34_RS18100	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B34_RS18105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B34_RS18110	COG0805	protein transport
B34_RS18120	COG1266	CAAX protease self-immunity
B34_RS18125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B34_RS18130	COG0459	protein refolding
B34_RS18165	COG2720	vancomycin resistance protein
B34_RS18180	COG2135	peptidase activity
B34_RS18190	COG1309	transcriptional regulator
B34_RS18195	COG3848	Pyruvate phosphate dikinase
B34_RS18195	COG0574	Belongs to the PEP-utilizing enzyme family
B34_RS18205	COG3189	MarR family transcriptional regulator
B34_RS18210	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
B34_RS18215	COG2272	Belongs to the type-B carboxylesterase lipase family
B34_RS18220	COG2814	Major facilitator Superfamily
B34_RS18225	COG1842	Phage shock protein A
B34_RS18230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B34_RS18235	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B34_RS18240	COG4260	virion core protein, lumpy skin disease virus
B34_RS18250	COG1378	Sugar-specific transcriptional regulator TrmB
B34_RS18255	COG1280	lysine exporter protein (LysE YggA)
B34_RS18260	COG3339	Conserved Protein
B34_RS18265	COG0772	Belongs to the SEDS family
B34_RS18270	COG0772	Belongs to the SEDS family
B34_RS18295	COG0726	polysaccharide deacetylase
B34_RS18310	COG1609	Transcriptional regulator
B34_RS18315	COG0366	Alpha amylase catalytic
B34_RS18320	COG2182	Extracellular solute-binding protein
B34_RS18325	COG1175	transmembrane transport
B34_RS18330	COG3833	ABC-type maltose transport systems, permease component
B34_RS18335	COG5521	maltodextrose utilization protein MalA
B34_RS18340	COG1554	hydrolase, family 65, central catalytic
B34_RS18345	COG0366	Alpha amylase catalytic
B34_RS18350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B34_RS18355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B34_RS18360	COG1846	Transcriptional regulator
B34_RS18375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B34_RS18380	COG0823	Involved in the tonB-independent uptake of proteins
B34_RS18410	COG0702	epimerase
B34_RS18420	COG2132	Multicopper oxidase
B34_RS18435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B34_RS18440	COG0714	Associated with various cellular activities
B34_RS18445	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B34_RS18450	COG1305	Transglutaminase-like
B34_RS18455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B34_RS18455	COG0519	Catalyzes the synthesis of GMP from XMP
B34_RS18465	COG2252	PERMEase
B34_RS18480	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
B34_RS18490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B34_RS18495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B34_RS18500	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B34_RS18505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B34_RS18510	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B34_RS18515	COG0047	phosphoribosylformylglycinamidine synthase activity
B34_RS18520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B34_RS18525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B34_RS18530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B34_RS18535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B34_RS18540	COG0138	bifunctional purine biosynthesis protein purh
B34_RS18545	COG0151	Belongs to the GarS family
B34_RS18555	COG2124	cytochrome p450
B34_RS18575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B34_RS18580	COG1470	cell adhesion involved in biofilm formation
B34_RS18585	COG4496	protein, YerC YecD
B34_RS18590	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B34_RS18595	COG0210	DNA helicase
B34_RS18600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B34_RS18605	COG4851	CamS sex pheromone cAM373 precursor
B34_RS18610	COG2188	Transcriptional regulator
B34_RS18630	COG1735	metal-dependent hydrolase with the TIM-barrel fold
B34_RS18635	COG0626	cystathionine gamma-synthase activity
B34_RS18640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B34_RS18645	COG3457	Alanine racemase
B34_RS18650	COG0363	glucosamine-6-phosphate deaminase activity
B34_RS18655	COG1285	pathogenesis
B34_RS18660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B34_RS18665	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B34_RS18670	COG0154	amidase activity
B34_RS18675	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B34_RS18690	COG4124	Belongs to the glycosyl hydrolase 26 family
B34_RS18695	COG1309	transcriptional regulator
B34_RS18700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B34_RS18710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B34_RS18715	COG1957	nucleoside hydrolase
B34_RS18720	COG1597	lipid kinase activity
B34_RS18725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B34_RS18735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS18735	COG2190	(PTS) system
B34_RS18735	COG1263	PTS System
B34_RS18740	COG2723	6-phospho-beta-galactosidase activity
B34_RS18745	COG3711	transcriptional antiterminator
B34_RS18750	COG0457	Tetratricopeptide repeat
B34_RS18770	COG0217	transcriptional regulatory protein
B34_RS18785	COG1012	belongs to the aldehyde dehydrogenase family
B34_RS18790	COG0840	transmembrane signaling receptor activity
B34_RS18795	COG0471	metal ion transport
B34_RS18800	COG0488	(ABC) transporter
B34_RS18810	COG1469	GTP cyclohydrolase I activity
B34_RS18825	COG0523	cobalamin synthesis protein
B34_RS18830	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
B34_RS18835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B34_RS18840	COG0156	8-amino-7-oxononanoate synthase activity
B34_RS18845	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B34_RS18850	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B34_RS18855	COG2124	cytochrome p450
B34_RS18865	COG0789	Transcriptional regulator
B34_RS18870	COG2814	Major facilitator Superfamily
B34_RS18875	COG0488	(ABC) transporter
B34_RS18880	COG0513	Belongs to the DEAD box helicase family
B34_RS18885	COG2130	NADP-dependent
B34_RS18900	COG0471	metal ion transport
B34_RS18915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B34_RS18925	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B34_RS18930	COG5658	integral membrane protein
B34_RS18935	COG0640	Transcriptional regulator
B34_RS18940	COG1254	Belongs to the acylphosphatase family
B34_RS18945	COG2258	MOSC domain
B34_RS18955	COG0024	Methionine aminopeptidase
B34_RS18960	COG1368	sulfuric ester hydrolase activity
B34_RS18970	COG1115	amino acid carrier protein
B34_RS18975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS18975	COG1263	PTS System
B34_RS18980	COG0366	Alpha amylase catalytic
B34_RS18985	COG2188	Transcriptional regulator
B34_RS19010	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B34_RS19015	COG1045	serine acetyltransferase
B34_RS19020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B34_RS19030	COG1215	transferase activity, transferring glycosyl groups
B34_RS19035	COG0463	Glycosyl transferase, family 2
B34_RS19035	COG0457	Tetratricopeptide repeat
B34_RS19045	COG0673	inositol 2-dehydrogenase activity
B34_RS19055	COG0657	acetylesterase activity
B34_RS19060	COG1733	regulation of RNA biosynthetic process
B34_RS19065	COG0778	Nitroreductase
B34_RS19070	COG0737	Belongs to the 5'-nucleotidase family
B34_RS19075	COG0693	protein deglycase activity
B34_RS19080	COG4840	Belongs to the UPF0435 family
B34_RS19085	COG1115	amino acid carrier protein
B34_RS19090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B34_RS19095	COG4980	gas vesicle protein
B34_RS19100	COG1295	ribonuclease BN
B34_RS19105	COG0477	Major facilitator Superfamily
B34_RS19115	COG0387	Pfam Sodium calcium exchanger
B34_RS19125	COG0535	radical SAM domain protein
B34_RS19135	COG0726	polysaccharide deacetylase
B34_RS19140	COG0371	Dehydrogenase
B34_RS19150	COG0598	Magnesium transport protein CorA
B34_RS19155	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B34_RS19160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B34_RS19165	COG4637	Psort location Cytoplasmic, score
B34_RS19190	COG1819	glycosyl
B34_RS19205	COG0477	Major facilitator Superfamily
B34_RS19210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS19210	COG1263	PTS System
B34_RS19215	COG3711	transcriptional antiterminator
B34_RS19225	COG0288	reversible hydration of carbon dioxide
B34_RS19230	COG3002	Belongs to the UPF0753 family
B34_RS19235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B34_RS19240	COG5609	conserved protein (DUF2294)
B34_RS19250	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B34_RS19255	COG0022	dehydrogenase e1 component
B34_RS19260	COG0508	dehydrogenase complex catalyzes the overall conversion of
B34_RS19265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B34_RS19270	COG3284	Transcriptional regulator
B34_RS19275	COG1742	UPF0060 membrane protein
B34_RS19280	COG1486	melibiose metabolic process
B34_RS19285	COG1737	Transcriptional regulator
B34_RS19290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS19290	COG1263	PTS System
B34_RS19305	COG1733	regulation of RNA biosynthetic process
B34_RS19310	COG2259	Doxx family
B34_RS19315	COG2514	catechol 2,3-dioxygenase activity
B34_RS19325	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_RS19330	COG2207	Transcriptional regulator
B34_RS19330	COG1917	Cupin 2, conserved barrel domain protein
B34_RS19340	COG2249	NAD(P)H dehydrogenase (quinone) activity
B34_RS19345	COG1051	belongs to the nudix hydrolase family
B34_RS19355	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B34_RS19355	COG0392	lysyltransferase activity
B34_RS19365	COG0384	phenazine biosynthesis protein PhzF
B34_RS19370	COG0778	Nitroreductase
B34_RS19390	COG1090	epimerase
B34_RS19395	COG2137	regulation of response to DNA damage stimulus
B34_RS19425	COG0463	Glycosyl transferase, family 2
B34_RS19435	COG4485	Bacterial membrane protein, YfhO
B34_RS19440	COG1988	membrane-bound metal-dependent
B34_RS19445	COG1194	a g-specific adenine glycosylase
B34_RS19455	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS19470	COG3557	Belongs to the UPF0374 family
B34_RS19475	COG1132	(ABC) transporter
B34_RS19480	COG0444	Belongs to the ABC transporter superfamily
B34_RS19485	COG4608	Belongs to the ABC transporter superfamily
B34_RS19490	COG0747	negative chemotaxis
B34_RS19495	COG0601	transmembrane transport
B34_RS19500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS19505	COG4129	membrane
B34_RS19510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B34_RS19515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B34_RS19520	COG0735	belongs to the Fur family
B34_RS19735	COG0582	viral genome integration into host DNA
B34_RS19770	COG1802	Transcriptional regulator
B34_RS19770	COG4626	Terminase
B34_RS19830	COG5280	Phage tail tape measure protein TP901
B34_RS19830	COG3953	SLT domain
B34_RS19840	COG1705	Flagellar rod assembly protein muramidase FlgJ
B34_RS19845	COG5434	Belongs to the glycosyl hydrolase 28 family
B34_RS19885	COG5444	nuclease activity
B34_RS19890	COG0457	Tetratricopeptide repeat
B34_RS19905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B34_RS19955	COG5444	nuclease activity
B34_RS19960	COG0457	Tetratricopeptide repeat
B34_RS19965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B34_RS19975	COG0710	3-dehydroquinate dehydratase activity
B34_RS19980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B34_RS19985	COG1116	anion transmembrane transporter activity
B34_RS19990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B34_RS19995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B34_RS20000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B34_RS20010	COG1476	TRANSCRIPTIONal
B34_RS20020	COG1131	(ABC) transporter
B34_RS20040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
B34_RS20050	COG3382	B3 4 domain protein
B34_RS20055	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B34_RS20065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B34_RS20070	COG0789	Transcriptional regulator
B34_RS20075	COG1664	Polymer-forming cytoskeletal
B34_RS20085	COG2766	serine protein kinase
B34_RS20090	COG2718	Belongs to the UPF0229 family
B34_RS20095	COG1566	PFAM secretion protein HlyD family protein
B34_RS20100	COG2814	Major facilitator Superfamily
B34_RS20105	COG0655	NAD(P)H dehydrogenase (quinone) activity
B34_RS20125	COG1131	(ABC) transporter
B34_RS20130	COG1131	(ABC) transporter
B34_RS20135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B34_RS20145	COG1278	Cold shock
B34_RS20150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B34_RS20155	COG2011	ABC-type metal ion transport system permease component
B34_RS20160	COG1464	Belongs to the NlpA lipoprotein family
B34_RS20165	COG1823	symporter activity
B34_RS20190	COG5577	PFAM Coat F domain
B34_RS20195	COG5002	protein histidine kinase activity
B34_RS20200	COG1525	nuclease
B34_RS20200	COG4085	toxin activity
B34_RS20200	COG0737	Belongs to the 5'-nucleotidase family
B34_RS20205	COG3764	Sortase (surface protein transpeptidase)
B34_RS20210	COG0564	pseudouridine synthase activity
B34_RS20220	COG0517	IMP dehydrogenase activity
B34_RS20225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B34_RS20230	COG3153	acetyltransferase
B34_RS20230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B34_RS20235	COG0488	(ABC) transporter
B34_RS20245	COG2116	formate transmembrane transporter activity
B34_RS20250	COG0679	Auxin Efflux Carrier
B34_RS20255	COG0604	alcohol dehydrogenase
B34_RS20260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B34_RS20265	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B34_RS20270	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B34_RS20275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B34_RS20280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B34_RS20295	COG2203	Gaf domain
B34_RS20295	COG4585	Histidine kinase
B34_RS20300	COG2197	response regulator
B34_RS20305	COG0431	NADPH-dependent FMN reductase
B34_RS20320	COG1959	2 iron, 2 sulfur cluster binding
B34_RS20325	COG1017	nitric oxide dioxygenase activity
B34_RS20325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B34_RS20330	COG2719	SpoVR family
B34_RS20335	COG1388	LysM domain
B34_RS20335	COG0791	NLP P60 protein
B34_RS20340	COG0583	DNA-binding transcription factor activity
B34_RS20345	COG0372	Belongs to the citrate synthase family
B34_RS20350	COG2133	pyrroloquinoline quinone binding
B34_RS20355	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS20360	COG0733	neurotransmitter:sodium symporter activity
B34_RS20370	COG3708	Transcriptional regulator
B34_RS20370	COG2207	Transcriptional regulator
B34_RS20375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_RS20395	COG1595	DNA-templated transcription, initiation
B34_RS20400	COG0662	Cupin 2, conserved barrel domain protein
B34_RS20410	COG0204	Acyl-transferase
B34_RS20415	COG3152	Membrane
B34_RS20425	COG1309	transcriptional regulator
B34_RS20430	COG1253	flavin adenine dinucleotide binding
B34_RS20435	COG0789	Transcriptional regulator
B34_RS20440	COG1253	flavin adenine dinucleotide binding
B34_RS20460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B34_RS20465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B34_RS20470	COG0584	glycerophosphoryl diester phosphodiesterase
B34_RS20475	COG0668	transmembrane transport
B34_RS20480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B34_RS20495	COG0726	polysaccharide deacetylase
B34_RS20505	COG1757	Na H antiporter
B34_RS20510	COG2017	converts alpha-aldose to the beta-anomer
B34_RS20535	COG0589	response to stress
B34_RS20540	COG1132	(ABC) transporter
B34_RS20545	COG1132	(ABC) transporter
B34_RS20550	COG0702	epimerase
B34_RS20565	COG3842	ATPase activity
B34_RS20570	COG2508	Transcriptional regulator
B34_RS20580	COG0189	ligase activity
B34_RS20585	COG0189	ligase activity
B34_RS20590	COG4399	Belongs to the UPF0754 family
B34_RS20595	COG3679	Belongs to the UPF0342 family
B34_RS20605	COG0561	phosphatase activity
B34_RS20610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B34_RS20615	COG0475	glutathione-regulated potassium exporter activity
B34_RS20620	COG0490	domain, Protein
B34_RS20630	COG1024	Enoyl-CoA hydratase
B34_RS20650	COG4152	abc transporter atp-binding protein
B34_RS20655	COG1668	transmembrane transport
B34_RS20660	COG0420	3'-5' exonuclease activity
B34_RS20665	COG4717	serine-type aminopeptidase activity
B34_RS20670	COG3481	metal-dependent phosphohydrolase, HD sub domain
B34_RS20680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B34_RS20710	COG1846	Transcriptional regulator
B34_RS20715	COG4980	gas vesicle protein
B34_RS20730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B34_RS20735	COG0537	adenosine 5'-monophosphoramidase activity
B34_RS20745	COG1131	(ABC) transporter
B34_RS20750	COG4473	ABC transporter
B34_RS20760	COG1473	amidohydrolase
B34_RS20765	COG3069	C4-dicarboxylate transmembrane transporter activity
B34_RS20770	COG2329	Antibiotic biosynthesis monooxygenase
B34_RS20775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B34_RS20780	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B34_RS20785	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B34_RS20790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B34_RS20795	COG1309	transcriptional regulator
B34_RS20800	COG1511	domain protein
B34_RS20805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_RS20810	COG1363	Peptidase, m42
B34_RS20820	COG1301	dicarboxylic acid transport
B34_RS20830	COG1234	tRNA 3'-trailer cleavage
B34_RS20835	COG0095	Lipoate-protein ligase
B34_RS20840	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS20850	COG1396	sequence-specific DNA binding
B34_RS20865	COG0501	Belongs to the peptidase M48B family
B34_RS20875	COG0697	spore germination
B34_RS20880	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B34_RS20885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS20890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B34_RS20895	COG0406	alpha-ribazole phosphatase activity
B34_RS20900	COG0840	transmembrane signaling receptor activity
B34_RS20905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B34_RS20905	COG0723	plastoquinol--plastocyanin reductase activity
B34_RS20910	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS20920	COG4903	ComK protein
B34_RS20930	COG0398	Pfam SNARE associated Golgi protein
B34_RS20935	COG0681	Belongs to the peptidase S26 family
B34_RS20940	COG1404	Belongs to the peptidase S8 family
B34_RS20950	COG2508	Transcriptional regulator
B34_RS20960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B34_RS20965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B34_RS20970	COG3257	ureidoglycine aminohydrolase activity
B34_RS20975	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
B34_RS20985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_RS20990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B34_RS21000	COG0549	Belongs to the carbamate kinase family
B34_RS21005	COG2814	Major facilitator Superfamily
B34_RS21015	COG0457	Tetratricopeptide repeat
B34_RS21035	COG1609	Transcriptional regulator
B34_RS21040	COG1653	transport
B34_RS21045	COG1175	transmembrane transport
B34_RS21050	COG0395	ABC-type sugar transport system, permease component
B34_RS21055	COG1486	melibiose metabolic process
B34_RS21060	COG3180	Ammonia monooxygenase
B34_RS21075	COG3546	catalase activity
B34_RS21080	COG0318	PFAM AMP-dependent synthetase and ligase
B34_RS21085	COG2814	Major facilitator Superfamily
B34_RS21085	COG0477	Major facilitator Superfamily
B34_RS21095	COG5002	protein histidine kinase activity
B34_RS21100	COG0745	RESPONSE REGULATOR receiver
B34_RS21105	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B34_RS21110	COG0725	ABC transporter, periplasmic molybdate-binding protein
B34_RS21115	COG4149	molybdate abc transporter
B34_RS21120	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B34_RS21125	COG1074	ATP-dependent DNA helicase activity
B34_RS21130	COG0420	3'-5' exonuclease activity
B34_RS21135	COG0419	ATPase involved in DNA repair
B34_RS21180	COG5337	Spore coat protein CotH
B34_RS21190	COG0179	Fumarylacetoacetate (FAA) hydrolase
B34_RS21210	COG0367	asparagine synthase
B34_RS21220	COG0347	Belongs to the P(II) protein family
B34_RS21225	COG0534	Mate efflux family protein
B34_RS21230	COG2207	Transcriptional regulator
B34_RS21230	COG1917	Cupin 2, conserved barrel domain protein
B34_RS21240	COG1609	Transcriptional regulator
B34_RS21265	COG1279	arginine transmembrane transporter activity
B34_RS21270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B34_RS21280	COG0076	glutamate decarboxylase activity
B34_RS21305	COG2153	protein acetylation
B34_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS21315	COG2378	regulation of single-species biofilm formation
B34_RS21320	COG1410	methionine synthase
B34_RS21320	COG0646	methionine synthase
B34_RS21325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B34_RS21325	COG0646	methionine synthase
B34_RS21330	COG1666	GTP binding
B34_RS21335	COG2996	Protein conserved in bacteria
B34_RS21345	COG1307	EDD domain protein, DegV family
B34_RS21350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B34_RS21360	COG0516	GMP reductase activity
B34_RS21370	COG0561	phosphatase activity
B34_RS21375	COG1073	alpha beta
B34_RS21380	COG2151	metal-sulfur cluster biosynthetic enzyme
B34_RS21390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B34_RS21395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B34_RS21400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B34_RS21405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B34_RS21410	COG0505	Belongs to the CarA family
B34_RS21415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B34_RS21420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B34_RS21425	COG1968	undecaprenyl-diphosphatase activity
B34_RS21440	COG2267	carboxylic ester hydrolase activity
B34_RS21450	COG1744	ABC transporter substrate-binding protein PnrA-like
B34_RS21465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B34_RS21470	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B34_RS21475	COG5504	Zn-dependent protease
B34_RS21480	COG0444	Belongs to the ABC transporter superfamily
B34_RS21485	COG4608	Belongs to the ABC transporter superfamily
B34_RS21495	COG0601	transmembrane transport
B34_RS21500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS21525	COG0180	Tryptophanyl-tRNA synthetase
B34_RS21535	COG4166	transmembrane transport
B34_RS21540	COG0601	transmembrane transport
B34_RS21545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS21550	COG0444	Belongs to the ABC transporter superfamily
B34_RS21555	COG4608	Belongs to the ABC transporter superfamily
B34_RS21560	COG0456	acetyltransferase
B34_RS21565	COG1393	Belongs to the ArsC family
B34_RS21570	COG0861	Integral membrane protein TerC family
B34_RS21575	COG4862	establishment of competence for transformation
B34_RS21595	COG4565	transcriptional regulatory protein
B34_RS21600	COG3290	protein histidine kinase activity
B34_RS21605	COG4469	Competence protein
B34_RS21610	COG1164	Oligoendopeptidase f
B34_RS21620	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B34_RS21625	COG2346	COG2346, Truncated hemoglobins
B34_RS21630	COG0741	lytic transglycosylase activity
B34_RS21635	COG4116	CYTH
B34_RS21645	COG2357	RelA SpoT domain protein
B34_RS21650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B34_RS21655	COG0564	pseudouridine synthase activity
B34_RS21660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B34_RS21670	COG0569	domain protein
B34_RS21670	COG0475	glutathione-regulated potassium exporter activity
B34_RS21675	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B34_RS21680	COG0352	thiamine-phosphate diphosphorylase activity
B34_RS21690	COG2104	thiamine diphosphate biosynthetic process
B34_RS21695	COG2022	thiamine diphosphate biosynthetic process
B34_RS21700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B34_RS21705	COG0351	phosphomethylpyrimidine kinase
B34_RS21710	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B34_RS21765	COG0210	DNA helicase
B34_RS21775	COG0586	Pfam SNARE associated Golgi protein
B34_RS21780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B34_RS21785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B34_RS21790	COG2246	polysaccharide biosynthetic process
B34_RS21795	COG2153	protein acetylation
B34_RS21800	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B34_RS21805	COG2382	esterase
B34_RS21825	COG0626	cystathionine gamma-synthase activity
B34_RS21830	COG0626	cystathionine gamma-synthase activity
B34_RS21835	COG5505	Protein of unknown function (DUF819)
B34_RS21850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B34_RS21855	COG3507	Belongs to the glycosyl hydrolase 43 family
B34_RS21875	COG0110	maltose O-acetyltransferase activity
B34_RS21885	COG0583	DNA-binding transcription factor activity
B34_RS21895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B34_RS21900	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B34_RS21905	COG0583	DNA-binding transcription factor activity
B34_RS21910	COG0697	spore germination
B34_RS21915	COG0346	lactoylglutathione lyase activity
B34_RS21925	COG3584	3D domain protein
B34_RS21925	COG1388	LysM domain
B34_RS21930	COG2814	Major facilitator Superfamily
B34_RS21935	COG1309	transcriptional regulator
B34_RS21960	COG4195	phage-related replication protein
B34_RS21965	COG2856	Zn peptidase
B34_RS21970	COG1396	sequence-specific DNA binding
B34_RS21985	COG1522	sequence-specific DNA binding
B34_RS21990	COG1484	DNA-dependent DNA replication
B34_RS22005	COG1595	DNA-templated transcription, initiation
B34_RS22010	COG3728	DNA packaging
B34_RS22010	COG5484	DNA packaging
B34_RS22015	COG1783	phage Terminase large subunit
B34_RS22025	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B34_RS22030	COG4653	Phage capsid family
B34_RS22075	COG5412	phage tail tape measure protein
B34_RS22075	COG3953	SLT domain
B34_RS22080	COG1652	LysM domain
B34_RS22085	COG4193	domain, Protein
B34_RS22095	COG3628	GPW Gp25 family protein
B34_RS22100	COG3299	homolog of phage Mu protein gp47
B34_RS22105	COG3778	Protein conserved in bacteria
B34_RS22140	COG1802	Transcriptional regulator
B34_RS22145	COG1063	alcohol dehydrogenase
B34_RS22150	COG1312	Catalyzes the dehydration of D-mannonate
B34_RS22155	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS22160	COG1063	alcohol dehydrogenase
B34_RS22165	COG2271	Major facilitator Superfamily
B34_RS22180	COG0306	phosphate transporter
B34_RS22185	COG1392	Phosphate transport regulator
B34_RS22190	COG0405	Gamma-glutamyltransferase
B34_RS22200	COG2972	Histidine kinase
B34_RS22205	COG4753	response regulator
B34_RS22205	COG2207	Transcriptional regulator
B34_RS22210	COG1653	transport
B34_RS22215	COG1175	transmembrane transport
B34_RS22220	COG0395	ABC-type sugar transport system, permease component
B34_RS22225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
B34_RS22230	COG2207	Transcriptional regulator
B34_RS22235	COG2755	lipolytic protein G-D-S-L family
B34_RS22245	COG5578	integral membrane protein
B34_RS22250	COG3401	FG-GAP repeat protein
B34_RS22260	COG2755	lipolytic protein G-D-S-L family
B34_RS22265	COG3401	FG-GAP repeat protein
B34_RS22270	COG0667	Aldo Keto reductase
B34_RS22275	COG2755	lipolytic protein G-D-S-L family
B34_RS22280	COG1874	Beta-galactosidase
B34_RS22290	COG1653	transport
B34_RS22295	COG4209	transmembrane transport
B34_RS22300	COG0395	ABC-type sugar transport system, permease component
B34_RS22305	COG0531	amino acid
B34_RS22310	COG0346	lactoylglutathione lyase activity
B34_RS22320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B34_RS22325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B34_RS22330	COG2362	D-Aminopeptidase
B34_RS22335	COG0601	transmembrane transport
B34_RS22340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B34_RS22345	COG0444	Belongs to the ABC transporter superfamily
B34_RS22350	COG4166	transmembrane transport
B34_RS22355	COG1619	proteins homologs of microcin C7 resistance protein MccF
B34_RS22360	COG4948	Mandelate Racemase Muconate Lactonizing
B34_RS22365	COG0791	NLP P60 protein
B34_RS22370	COG4608	Belongs to the ABC transporter superfamily
B34_RS22375	COG1834	amidinotransferase
B34_RS22380	COG1607	acyl-coa hydrolase
B34_RS22385	COG2323	membrane
B34_RS22390	COG3866	Pectate lyase
B34_RS22410	COG2318	DinB family
B34_RS22415	COG2076	Multidrug Resistance protein
B34_RS22420	COG2076	Multidrug Resistance protein
B34_RS22425	COG0788	formyltetrahydrofolate deformylase activity
B34_RS22430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B34_RS22435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B34_RS22440	COG1764	response to oxidative stress
B34_RS22445	COG1846	Transcriptional regulator
B34_RS22450	COG1764	response to oxidative stress
B34_RS22460	COG0590	tRNA wobble adenosine to inosine editing
B34_RS22465	COG0406	alpha-ribazole phosphatase activity
B34_RS22480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B34_RS22485	COG1404	Belongs to the peptidase S8 family
B34_RS22490	COG2239	Acts as a magnesium transporter
B34_RS22500	COG0789	Transcriptional regulator
B34_RS22510	COG1846	Transcriptional regulator
B34_RS22515	COG3285	dna ligase
B34_RS22515	COG1793	dna ligase
B34_RS22520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B34_RS22525	COG5001	Diguanylate cyclase
B34_RS22525	COG3300	MHYT domain
B34_RS22530	COG0586	Pfam SNARE associated Golgi protein
B34_RS22535	COG0861	Integral membrane protein TerC family
B34_RS22540	COG1191	sigma factor activity
B34_RS22560	COG0501	Belongs to the peptidase M48B family
B34_RS22565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B34_RS22570	COG0768	penicillin binding
B34_RS22585	COG3594	Acyltransferase
B34_RS22590	COG5002	protein histidine kinase activity
B34_RS22595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B34_RS22600	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B34_RS22605	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B34_RS22610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B34_RS22615	COG0436	Aminotransferase
B34_RS22620	COG1850	ribulose-bisphosphate carboxylase activity
B34_RS22625	COG0235	Class ii aldolase
B34_RS22625	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B34_RS22630	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B34_RS22635	COG0346	lactoylglutathione lyase activity
B34_RS22640	COG3339	Conserved Protein
B34_RS22650	COG3852	Histidine kinase
B34_RS22655	COG1846	Transcriptional regulator
B34_RS22660	COG1360	Flagellar Motor Protein
B34_RS22665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B34_RS22670	COG0542	response to heat
B34_RS22675	COG3949	Membrane
B34_RS22680	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B34_RS22685	COG0720	synthase
B34_RS22690	COG0602	queuosine metabolic process
B34_RS22695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B34_RS22705	COG4974	Belongs to the 'phage' integrase family
B34_RS22710	COG4974	Belongs to the 'phage' integrase family
B34_RS22760	COG5444	nuclease activity
B34_RS22845	COG0582	viral genome integration into host DNA
B34_RS22975	COG5632	N-Acetylmuramoyl-L-alanine amidase
B34_RS22975	COG3409	Peptidoglycan-binding domain 1 protein
B34_RS22975	COG1388	LysM domain
B34_RS23005	COG0582	viral genome integration into host DNA
B34_RS23010	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B34_RS23020	COG3739	integral membrane protein
B34_RS23025	COG3655	Transcriptional regulator
B34_RS23055	COG4873	Protein conserved in bacteria
B34_RS23065	COG3773	Cell wall hydrolase
B34_RS23070	COG2244	polysaccharide biosynthetic process
B34_RS23075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS23080	COG2217	Heavy metal translocating P-type atpase
B34_RS23085	COG0006	proline dipeptidase activity
B34_RS23095	COG1609	Transcriptional regulator
B34_RS23100	COG3711	transcriptional antiterminator
B34_RS23105	COG2190	(PTS) system
B34_RS23105	COG1263	PTS System
B34_RS23105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B34_RS23110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS23115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B34_RS23125	COG1533	DNA photolyase activity
B34_RS23130	COG0456	acetyltransferase
B34_RS23135	COG0840	transmembrane signaling receptor activity
B34_RS23140	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS23145	COG2084	Dehydrogenase
B34_RS23150	COG2340	Cysteine-rich secretory protein family
B34_RS23155	COG0768	penicillin binding
B34_RS23160	COG4191	Histidine kinase
B34_RS23165	COG0436	Aminotransferase
B34_RS23170	COG1714	RDD family
B34_RS23180	COG0835	chemotaxis
B34_RS23180	COG0784	Response regulator, receiver
B34_RS23190	COG2814	Major facilitator Superfamily
B34_RS23195	COG1376	ErfK ybiS ycfS ynhG family protein
B34_RS23205	COG1408	metallophosphoesterase
B34_RS23210	COG1028	Short-chain dehydrogenase reductase Sdr
B34_RS23215	COG2200	EAL domain
B34_RS23225	COG4703	Protein of unknown function (DUF1797)
B34_RS23230	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B34_RS23240	COG0517	IMP dehydrogenase activity
B34_RS23245	COG0583	DNA-binding transcription factor activity
B34_RS23250	COG0716	FMN binding
B34_RS23260	COG0716	FMN binding
B34_RS23265	COG2171	N-acyltransferase activity
B34_RS23270	COG1473	amidohydrolase
B34_RS23280	COG0450	alkyl hydroperoxide reductase
B34_RS23285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B34_RS23300	COG0746	molybdenum cofactor guanylyltransferase activity
B34_RS23305	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B34_RS23310	COG0303	'Molybdopterin
B34_RS23315	COG1763	Mo-molybdopterin cofactor biosynthetic process
B34_RS23320	COG0314	molybdopterin synthase activity
B34_RS23325	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B34_RS23335	COG1132	(ABC) transporter
B34_RS23340	COG1132	(ABC) transporter
B34_RS23350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B34_RS23355	COG1136	(ABC) transporter
B34_RS23360	COG0577	efflux transmembrane transporter activity
B34_RS23365	COG1349	DNA-binding transcription factor activity
B34_RS23370	COG1105	Belongs to the carbohydrate kinase PfkB family
B34_RS23375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS23375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B34_RS23375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B34_RS23395	COG0488	(ABC) transporter