locus-tag	class	description
EQY74_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQY74_RS00010	COG0592	DNA-directed DNA polymerase activity
EQY74_RS00015	COG2501	S4 domain
EQY74_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EQY74_RS00030	COG0187	DNA topoisomerase II activity
EQY74_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQY74_RS00070	COG0517	IMP dehydrogenase activity
EQY74_RS00070	COG0516	GMP reductase activity
EQY74_RS00075	COG1686	Belongs to the peptidase S11 family
EQY74_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EQY74_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EQY74_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EQY74_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
EQY74_RS00100	COG2610	gluconate transmembrane transporter activity
EQY74_RS00105	COG3835	regulator
EQY74_RS00120	COG1428	Deoxynucleoside kinase
EQY74_RS00125	COG1428	Deoxynucleoside kinase
EQY74_RS00135	COG1335	isochorismatase
EQY74_RS00140	COG0590	tRNA wobble adenosine to inosine editing
EQY74_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EQY74_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EQY74_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EQY74_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
EQY74_RS00210	COG3853	Toxic anion resistance protein (TelA)
EQY74_RS00215	COG1982	Orn Lys Arg decarboxylase major
EQY74_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EQY74_RS00225	COG3870	Protein conserved in bacteria
EQY74_RS00230	COG1728	Protein conserved in bacteria
EQY74_RS00235	COG0470	DNA polymerase III
EQY74_RS00240	COG1774	PSP1 C-terminal conserved region
EQY74_RS00245	COG4467	Involved in initiation control of chromosome replication
EQY74_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EQY74_RS00255	COG2827	Endonuclease containing a URI domain
EQY74_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EQY74_RS00265	COG2002	toxin-antitoxin pair type II binding
EQY74_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQY74_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQY74_RS00275	COG0084	hydrolase, TatD family'
EQY74_RS00280	COG3584	3D domain protein
EQY74_RS00280	COG3583	domain protein
EQY74_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQY74_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EQY74_RS00300	COG4466	Protein conserved in bacteria
EQY74_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EQY74_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQY74_RS00320	COG0251	oxidation-reduction process
EQY74_RS00325	COG2088	sporulation resulting in formation of a cellular spore
EQY74_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EQY74_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EQY74_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EQY74_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
EQY74_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EQY74_RS00360	COG2002	toxin-antitoxin pair type II binding
EQY74_RS00365	COG2244	polysaccharide biosynthetic process
EQY74_RS00370	COG3956	TIGRFAM MazG family protein
EQY74_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EQY74_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EQY74_RS00395	COG1098	S1 RNA binding domain
EQY74_RS00410	COG2208	phosphoserine phosphatase activity
EQY74_RS00415	COG2304	oxidoreductase activity
EQY74_RS00420	COG0515	serine threonine protein kinase
EQY74_RS00425	COG0037	tRNA processing
EQY74_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EQY74_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQY74_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EQY74_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EQY74_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQY74_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQY74_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQY74_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
EQY74_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQY74_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EQY74_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EQY74_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EQY74_RS00495	COG1396	sequence-specific DNA binding
EQY74_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EQY74_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EQY74_RS00585	COG4463	regulation of RNA biosynthetic process
EQY74_RS00590	COG3880	PFAM UvrB UvrC protein
EQY74_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EQY74_RS00600	COG0542	response to heat
EQY74_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EQY74_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EQY74_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
EQY74_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EQY74_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EQY74_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EQY74_RS00635	COG1045	serine acetyltransferase
EQY74_RS00640	COG0215	cysteine-tRNA ligase activity
EQY74_RS00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EQY74_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQY74_RS00655	COG3688	RNA-binding protein containing a PIN domain
EQY74_RS00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQY74_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
EQY74_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EQY74_RS00685	COG0081	regulation of translation
EQY74_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EQY74_RS00695	COG0222	ribosome binding
EQY74_RS00700	COG2813	Specifically methylates the guanine in position
EQY74_RS00705	COG0085	RNA polymerase activity
EQY74_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EQY74_RS00715	COG1358	cellular component organization or biogenesis
EQY74_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EQY74_RS00725	COG0049	tRNA binding
EQY74_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EQY74_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EQY74_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EQY74_RS00750	COG0088	Forms part of the polypeptide exit tunnel
EQY74_RS00755	COG0089	rRNA binding
EQY74_RS00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EQY74_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EQY74_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EQY74_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EQY74_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EQY74_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
EQY74_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EQY74_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EQY74_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EQY74_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EQY74_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQY74_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EQY74_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EQY74_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EQY74_RS00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EQY74_RS00835	COG1841	ribosomal large subunit assembly
EQY74_RS00840	COG0200	Binds to the 23S rRNA
EQY74_RS00845	COG0201	protein transport
EQY74_RS00850	COG0563	adenylate kinase activity
EQY74_RS00855	COG0024	Methionine aminopeptidase
EQY74_RS00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
EQY74_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EQY74_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EQY74_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EQY74_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EQY74_RS00885	COG0202	RNA polymerase activity
EQY74_RS00890	COG0203	ribosomal protein L17
EQY74_RS00895	COG1122	ATPase activity
EQY74_RS00900	COG1122	ATPase activity
EQY74_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQY74_RS00910	COG0101	tRNA pseudouridine synthase activity
EQY74_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EQY74_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EQY74_RS00925	COG2318	DinB family
EQY74_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS00940	COG0489	protein tyrosine kinase activity
EQY74_RS00950	COG2194	sulfuric ester hydrolase activity
EQY74_RS00955	COG0726	polysaccharide deacetylase
EQY74_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQY74_RS00995	COG0385	Bile acid
EQY74_RS01010	COG3876	Protein conserved in bacteria
EQY74_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
EQY74_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQY74_RS01025	COG1263	PTS System
EQY74_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS01030	COG1737	Transcriptional regulator
EQY74_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQY74_RS01040	COG1683	Conserved Protein
EQY74_RS01075	COG1595	DNA-templated transcription, initiation
EQY74_RS01080	COG5662	AntiSigma factor
EQY74_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EQY74_RS01090	COG4856	YbbR-like protein
EQY74_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQY74_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EQY74_RS01120	COG1725	Transcriptional regulator
EQY74_RS01125	COG0640	Transcriptional regulator
EQY74_RS01130	COG2814	Major facilitator Superfamily
EQY74_RS01140	COG1132	(ABC) transporter
EQY74_RS01145	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQY74_RS01170	COG1011	Hydrolase
EQY74_RS01175	COG1113	amino acid transport
EQY74_RS01180	COG2851	Citrate transporter
EQY74_RS01185	COG3181	Tripartite tricarboxylate transporter family receptor
EQY74_RS01190	COG4565	transcriptional regulatory protein
EQY74_RS01195	COG3290	protein histidine kinase activity
EQY74_RS01230	COG1331	Highly conserved protein containing a thioredoxin domain
EQY74_RS01245	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQY74_RS01250	COG1331	Highly conserved protein containing a thioredoxin domain
EQY74_RS01255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EQY74_RS01260	COG1331	Highly conserved protein containing a thioredoxin domain
EQY74_RS01270	COG0477	Major facilitator Superfamily
EQY74_RS01290	COG1283	sodium-dependent phosphate transmembrane transporter activity
EQY74_RS01295	COG4682	membrane
EQY74_RS01320	COG0697	spore germination
EQY74_RS01325	COG2207	Transcriptional regulator
EQY74_RS01325	COG1917	Cupin 2, conserved barrel domain protein
EQY74_RS01345	COG0371	Dehydrogenase
EQY74_RS01350	COG0840	transmembrane signaling receptor activity
EQY74_RS01355	COG4213	ABC transporter substrate-binding protein
EQY74_RS01370	COG4257	antibiotic catabolic process
EQY74_RS01380	COG0833	amino acid
EQY74_RS01385	COG2040	homocysteine
EQY74_RS01395	COG1263	PTS System
EQY74_RS01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS01395	COG2190	(PTS) system
EQY74_RS01400	COG0789	Transcriptional regulator
EQY74_RS01405	COG2323	membrane
EQY74_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQY74_RS01410	COG4451	ribulose bisphosphate carboxylase, small
EQY74_RS01420	COG2205	protein histidine kinase activity
EQY74_RS01425	COG1115	amino acid carrier protein
EQY74_RS01430	COG2066	Belongs to the glutaminase family
EQY74_RS01435	COG4191	Histidine kinase
EQY74_RS01440	COG0784	Response regulator, receiver
EQY74_RS01465	COG3540	Alkaline phosphatase
EQY74_RS01470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQY74_RS01475	COG0805	protein transport
EQY74_RS01480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQY74_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS01490	COG2271	Major facilitator Superfamily
EQY74_RS01495	COG4948	Mandelate Racemase Muconate Lactonizing
EQY74_RS01500	COG2186	Transcriptional regulator
EQY74_RS01505	COG2721	sulfolactate sulfo-lyase activity
EQY74_RS01510	COG0745	RESPONSE REGULATOR receiver
EQY74_RS01515	COG2205	protein histidine kinase activity
EQY74_RS01520	COG1131	(ABC) transporter
EQY74_RS01545	COG3173	Aminoglycoside phosphotransferase
EQY74_RS01550	COG1846	Transcriptional regulator
EQY74_RS01555	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS01575	COG0789	Transcriptional regulator
EQY74_RS01605	COG1714	RDD family
EQY74_RS01610	COG3012	SEC-C Motif Domain Protein
EQY74_RS01610	COG1405	negative regulation of cell septum assembly
EQY74_RS01615	COG1131	(ABC) transporter
EQY74_RS01640	COG0583	DNA-binding transcription factor activity
EQY74_RS01645	COG1942	4-Oxalocrotonate Tautomerase
EQY74_RS01650	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS01665	COG1288	antiporter activity
EQY74_RS01675	COG0456	acetyltransferase
EQY74_RS01685	COG1164	Oligoendopeptidase f
EQY74_RS01690	COG2261	transglycosylase associated protein
EQY74_RS01700	COG0247	lactate metabolic process
EQY74_RS01705	COG0277	FAD linked oxidase domain protein
EQY74_RS01710	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS01715	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQY74_RS01720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS01725	COG1486	melibiose metabolic process
EQY74_RS01730	COG2188	Transcriptional regulator
EQY74_RS01735	COG3394	polysaccharide catabolic process
EQY74_RS01750	COG3591	Belongs to the peptidase S1B family
EQY74_RS01755	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS01765	COG1595	DNA-templated transcription, initiation
EQY74_RS01775	COG3773	Cell wall hydrolase
EQY74_RS01780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQY74_RS01785	COG3883	PFAM NLP P60 protein
EQY74_RS01785	COG0791	NLP P60 protein
EQY74_RS01795	COG1131	(ABC) transporter
EQY74_RS01800	COG1309	transcriptional regulator
EQY74_RS01820	COG2310	stress, protein
EQY74_RS01825	COG2310	stress, protein
EQY74_RS01830	COG2310	stress, protein
EQY74_RS01835	COG0861	Integral membrane protein TerC family
EQY74_RS01855	COG3853	Toxic anion resistance protein (TelA)
EQY74_RS01860	COG0785	Cytochrome C biogenesis protein
EQY74_RS01870	COG0789	Transcriptional regulator
EQY74_RS01875	COG2223	nitrite transmembrane transporter activity
EQY74_RS01880	COG0039	L-malate dehydrogenase activity
EQY74_RS01885	COG1620	l-lactate permease
EQY74_RS01890	COG1280	lysine exporter protein (LysE YggA)
EQY74_RS01895	COG1113	amino acid transport
EQY74_RS01900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EQY74_RS01905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EQY74_RS01910	COG3541	Predicted nucleotidyltransferase
EQY74_RS01915	COG0506	proline dehydrogenase activity
EQY74_RS01920	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS01925	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS01930	COG2508	Transcriptional regulator
EQY74_RS01935	COG3689	TIGRFAM TIGR03943 family protein
EQY74_RS01940	COG0701	Predicted permease
EQY74_RS01945	COG3458	cephalosporin-C deacetylase activity
EQY74_RS01965	COG0765	amino acid transport
EQY74_RS01970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQY74_RS01975	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS01985	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS01995	COG3209	COG3209 Rhs family protein
EQY74_RS02005	COG3266	domain, Protein
EQY74_RS02005	COG0515	serine threonine protein kinase
EQY74_RS02015	COG5444	nuclease activity
EQY74_RS02040	COG1176	ABC-type spermidine putrescine transport system, permease component I
EQY74_RS02045	COG1177	transmembrane transport
EQY74_RS02050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQY74_RS02055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQY74_RS02060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQY74_RS02065	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EQY74_RS02070	COG0697	spore germination
EQY74_RS02085	COG2819	hydrolase of the alpha beta superfamily
EQY74_RS02095	COG2364	Membrane
EQY74_RS02105	COG1131	(ABC) transporter
EQY74_RS02130	COG1126	abc transporter atp-binding protein
EQY74_RS02135	COG0765	amino acid transport
EQY74_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQY74_RS02145	COG3829	transcription factor binding
EQY74_RS02150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQY74_RS02155	COG0833	amino acid
EQY74_RS02160	COG0010	Belongs to the arginase family
EQY74_RS02165	COG0583	DNA-binding transcription factor activity
EQY74_RS02170	COG0163	prenyltransferase activity
EQY74_RS02175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EQY74_RS02225	COG5444	nuclease activity
EQY74_RS02245	COG2972	Histidine kinase
EQY74_RS02250	COG4753	response regulator
EQY74_RS02250	COG2207	Transcriptional regulator
EQY74_RS02255	COG4213	ABC transporter substrate-binding protein
EQY74_RS02265	COG4214	carbohydrate transport
EQY74_RS02270	COG2271	Major facilitator Superfamily
EQY74_RS02275	COG1846	Transcriptional regulator
EQY74_RS02275	COG0456	acetyltransferase
EQY74_RS02280	COG1874	Beta-galactosidase
EQY74_RS02285	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
EQY74_RS02290	COG3104	oligopeptide transport
EQY74_RS02295	COG5434	Belongs to the glycosyl hydrolase 28 family
EQY74_RS02305	COG0697	spore germination
EQY74_RS02315	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EQY74_RS02320	COG0789	Transcriptional regulator
EQY74_RS02325	COG1136	(ABC) transporter
EQY74_RS02330	COG0577	efflux transmembrane transporter activity
EQY74_RS02335	COG0745	RESPONSE REGULATOR receiver
EQY74_RS02340	COG5002	protein histidine kinase activity
EQY74_RS02340	COG3850	Histidine kinase
EQY74_RS02350	COG0527	aspartate kinase activity
EQY74_RS02355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS02360	COG4605	iron ion homeostasis
EQY74_RS02365	COG4604	ABC transporter, ATP-binding protein
EQY74_RS02370	COG4607	ABC-type enterochelin transport system periplasmic component
EQY74_RS02375	COG2814	Major facilitator Superfamily
EQY74_RS02380	COG1309	transcriptional regulator
EQY74_RS02390	COG0778	Nitroreductase
EQY74_RS02395	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQY74_RS02400	COG0640	Transcriptional regulator
EQY74_RS02405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQY74_RS02410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EQY74_RS02415	COG0531	amino acid
EQY74_RS02420	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS02425	COG0697	spore germination
EQY74_RS02435	COG4549	nuclear export factor GLE1
EQY74_RS02440	COG2372	response to copper ion
EQY74_RS02440	COG1276	copper resistance
EQY74_RS02445	COG1349	DNA-binding transcription factor activity
EQY74_RS02450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQY74_RS02455	COG0243	molybdopterin cofactor binding
EQY74_RS02460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQY74_RS02465	COG2146	nitrite reductase [NAD(P)H] activity
EQY74_RS02470	COG1587	Uroporphyrinogen-III synthase
EQY74_RS02470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EQY74_RS02475	COG1802	Transcriptional regulator
EQY74_RS02480	COG0471	metal ion transport
EQY74_RS02485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQY74_RS02490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQY74_RS02505	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS02520	COG3959	Transketolase, thiamine diphosphate binding domain
EQY74_RS02525	COG3958	Transketolase
EQY74_RS02530	COG0561	phosphatase activity
EQY74_RS02535	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EQY74_RS02540	COG1914	H( )-stimulated, divalent metal cation uptake system
EQY74_RS02545	COG4336	lyase activity
EQY74_RS02550	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EQY74_RS02555	COG1984	allophanate hydrolase subunit 2
EQY74_RS02560	COG1414	Transcriptional regulator
EQY74_RS02565	COG2755	lipolytic protein G-D-S-L family
EQY74_RS02570	COG2213	PTS system mannitol-specific
EQY74_RS02575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS02580	COG0246	Mannitol dehydrogenase
EQY74_RS02585	COG3711	transcriptional antiterminator
EQY74_RS02590	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS02595	COG1917	Cupin 2, conserved barrel domain protein
EQY74_RS02605	COG3871	stress protein (general stress protein 26)
EQY74_RS02620	COG2814	Major facilitator Superfamily
EQY74_RS02630	COG1522	sequence-specific DNA binding
EQY74_RS02635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQY74_RS02635	COG0551	DNA topoisomerase type I activity
EQY74_RS02640	COG0531	amino acid
EQY74_RS02645	COG0028	Belongs to the TPP enzyme family
EQY74_RS02650	COG3397	chitin binding
EQY74_RS02660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQY74_RS02665	COG1914	H( )-stimulated, divalent metal cation uptake system
EQY74_RS02670	COG2261	transglycosylase associated protein
EQY74_RS02675	COG1027	Aspartate ammonia-lyase
EQY74_RS02680	COG1819	glycosyl
EQY74_RS02685	COG4876	unkown
EQY74_RS02690	COG2217	Heavy metal translocating P-type atpase
EQY74_RS02700	COG0662	Cupin 2, conserved barrel domain protein
EQY74_RS02710	COG0628	permease
EQY74_RS02715	COG1301	dicarboxylic acid transport
EQY74_RS02720	COG1131	(ABC) transporter
EQY74_RS02725	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQY74_RS02735	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS02750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS02755	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQY74_RS02760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EQY74_RS02770	COG0513	Belongs to the DEAD box helicase family
EQY74_RS02775	COG3402	PFAM membrane-flanked domain
EQY74_RS02780	COG3428	Bacterial PH domain
EQY74_RS02785	COG0705	Rhomboid family
EQY74_RS02790	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EQY74_RS02795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQY74_RS02800	COG0864	Transcriptional regulator
EQY74_RS02805	COG2337	Toxic component of a toxin-antitoxin (TA) module
EQY74_RS02810	COG1366	Belongs to the anti-sigma-factor antagonist family
EQY74_RS02815	COG1366	Belongs to the anti-sigma-factor antagonist family
EQY74_RS02820	COG2172	sigma factor antagonist activity
EQY74_RS02825	COG2208	phosphoserine phosphatase activity
EQY74_RS02835	COG2172	sigma factor antagonist activity
EQY74_RS02840	COG1191	sigma factor activity
EQY74_RS02845	COG2208	phosphoserine phosphatase activity
EQY74_RS02850	COG2183	response to ionizing radiation
EQY74_RS02855	COG1309	transcriptional regulator
EQY74_RS02860	COG1033	growth of symbiont in host cell
EQY74_RS02860	COG2409	Drug exporters of the RND superfamily
EQY74_RS02870	COG3091	SprT-like family
EQY74_RS02910	COG0582	viral genome integration into host DNA
EQY74_RS02915	COG2856	Zn peptidase
EQY74_RS02920	COG1396	sequence-specific DNA binding
EQY74_RS02945	COG1674	ftsk spoiiie
EQY74_RS02950	COG2946	Replication initiation factor
EQY74_RS02990	COG0433	COG0433 Predicted ATPase
EQY74_RS03000	COG5644	endopeptidase inhibitor activity
EQY74_RS03005	COG0791	NLP P60 protein
EQY74_RS03005	COG0741	lytic transglycosylase activity
EQY74_RS03030	COG0457	Tetratricopeptide repeat
EQY74_RS03035	COG0457	Tetratricopeptide repeat
EQY74_RS03050	COG1476	TRANSCRIPTIONal
EQY74_RS03055	COG3239	Fatty acid desaturase
EQY74_RS03060	COG1278	Cold shock
EQY74_RS03065	COG1063	alcohol dehydrogenase
EQY74_RS03075	COG2364	Membrane
EQY74_RS03080	COG1846	Transcriptional regulator
EQY74_RS03085	COG0456	acetyltransferase
EQY74_RS03090	COG2808	Putative FMN-binding domain
EQY74_RS03100	COG1733	regulation of RNA biosynthetic process
EQY74_RS03105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS03115	COG0583	DNA-binding transcription factor activity
EQY74_RS03130	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EQY74_RS03135	COG1113	amino acid transport
EQY74_RS03150	COG1595	DNA-templated transcription, initiation
EQY74_RS03160	COG2755	lipolytic protein G-D-S-L family
EQY74_RS03160	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EQY74_RS03165	COG2814	Major facilitator Superfamily
EQY74_RS03170	COG2972	Histidine kinase
EQY74_RS03170	COG0745	RESPONSE REGULATOR receiver
EQY74_RS03175	COG3279	Response regulator of the LytR AlgR family
EQY74_RS03185	COG3764	Sortase (surface protein transpeptidase)
EQY74_RS03195	COG2814	Major facilitator Superfamily
EQY74_RS03235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EQY74_RS03240	COG0802	atpase or kinase
EQY74_RS03245	COG1214	PFAM Peptidase M22, glycoprotease
EQY74_RS03250	COG0456	acetyltransferase
EQY74_RS03255	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EQY74_RS03260	COG0488	(ABC) transporter
EQY74_RS03265	COG0315	cyclic pyranopterin monophosphate synthase activity
EQY74_RS03270	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EQY74_RS03275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EQY74_RS03280	COG0805	protein transport
EQY74_RS03290	COG1266	CAAX protease self-immunity
EQY74_RS03295	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EQY74_RS03300	COG0459	protein refolding
EQY74_RS03305	COG4974	Belongs to the 'phage' integrase family
EQY74_RS03310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQY74_RS03405	COG0582	viral genome integration into host DNA
EQY74_RS03510	COG3953	SLT domain
EQY74_RS03510	COG5280	Phage tail tape measure protein TP901
EQY74_RS03565	COG5444	nuclease activity
EQY74_RS03605	COG2720	vancomycin resistance protein
EQY74_RS03620	COG2135	peptidase activity
EQY74_RS03630	COG1309	transcriptional regulator
EQY74_RS03635	COG3848	Pyruvate phosphate dikinase
EQY74_RS03635	COG0574	Belongs to the PEP-utilizing enzyme family
EQY74_RS03645	COG3189	MarR family transcriptional regulator
EQY74_RS03650	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EQY74_RS03655	COG2272	Belongs to the type-B carboxylesterase lipase family
EQY74_RS03660	COG2814	Major facilitator Superfamily
EQY74_RS03665	COG1842	Phage shock protein A
EQY74_RS03670	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQY74_RS03675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EQY74_RS03680	COG4260	virion core protein, lumpy skin disease virus
EQY74_RS03695	COG1378	Sugar-specific transcriptional regulator TrmB
EQY74_RS03700	COG1280	lysine exporter protein (LysE YggA)
EQY74_RS03705	COG3339	Conserved Protein
EQY74_RS03710	COG0772	Belongs to the SEDS family
EQY74_RS03715	COG0772	Belongs to the SEDS family
EQY74_RS03740	COG0726	polysaccharide deacetylase
EQY74_RS03750	COG1609	Transcriptional regulator
EQY74_RS03755	COG0366	Alpha amylase catalytic
EQY74_RS03760	COG2182	Extracellular solute-binding protein
EQY74_RS03765	COG1175	transmembrane transport
EQY74_RS03770	COG3833	ABC-type maltose transport systems, permease component
EQY74_RS03775	COG5521	maltodextrose utilization protein MalA
EQY74_RS03780	COG1554	hydrolase, family 65, central catalytic
EQY74_RS03785	COG0366	Alpha amylase catalytic
EQY74_RS03790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQY74_RS03795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQY74_RS03800	COG1846	Transcriptional regulator
EQY74_RS03815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EQY74_RS03820	COG0823	Involved in the tonB-independent uptake of proteins
EQY74_RS03850	COG0702	epimerase
EQY74_RS03860	COG2132	Multicopper oxidase
EQY74_RS03875	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EQY74_RS03880	COG0714	Associated with various cellular activities
EQY74_RS03885	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EQY74_RS03890	COG1305	Transglutaminase-like
EQY74_RS03895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EQY74_RS03895	COG0519	Catalyzes the synthesis of GMP from XMP
EQY74_RS03905	COG2252	PERMEase
EQY74_RS03920	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EQY74_RS03930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EQY74_RS03935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EQY74_RS03940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EQY74_RS03945	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EQY74_RS03950	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQY74_RS03955	COG0047	phosphoribosylformylglycinamidine synthase activity
EQY74_RS03960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EQY74_RS03965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EQY74_RS03970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EQY74_RS03975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EQY74_RS03980	COG0138	bifunctional purine biosynthesis protein purh
EQY74_RS03985	COG0151	Belongs to the GarS family
EQY74_RS04000	COG2124	cytochrome p450
EQY74_RS04020	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQY74_RS04025	COG1470	cell adhesion involved in biofilm formation
EQY74_RS04030	COG4496	protein, YerC YecD
EQY74_RS04035	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EQY74_RS04040	COG0210	DNA helicase
EQY74_RS04045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EQY74_RS04050	COG4851	CamS sex pheromone cAM373 precursor
EQY74_RS04060	COG2188	Transcriptional regulator
EQY74_RS04080	COG1735	metal-dependent hydrolase with the TIM-barrel fold
EQY74_RS04085	COG0626	cystathionine gamma-synthase activity
EQY74_RS04090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQY74_RS04095	COG3457	Alanine racemase
EQY74_RS04100	COG0363	glucosamine-6-phosphate deaminase activity
EQY74_RS04105	COG1285	pathogenesis
EQY74_RS04110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS04115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQY74_RS04120	COG0154	amidase activity
EQY74_RS04125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EQY74_RS04140	COG4124	Belongs to the glycosyl hydrolase 26 family
EQY74_RS04145	COG1309	transcriptional regulator
EQY74_RS04150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EQY74_RS04160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQY74_RS04165	COG1957	nucleoside hydrolase
EQY74_RS04170	COG1597	lipid kinase activity
EQY74_RS04175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQY74_RS04185	COG2190	(PTS) system
EQY74_RS04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS04185	COG1263	PTS System
EQY74_RS04190	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS04195	COG3711	transcriptional antiterminator
EQY74_RS04200	COG0457	Tetratricopeptide repeat
EQY74_RS04220	COG0217	transcriptional regulatory protein
EQY74_RS04235	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS04240	COG0840	transmembrane signaling receptor activity
EQY74_RS04245	COG0471	metal ion transport
EQY74_RS04250	COG0488	(ABC) transporter
EQY74_RS04260	COG1469	GTP cyclohydrolase I activity
EQY74_RS04275	COG0523	cobalamin synthesis protein
EQY74_RS04280	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EQY74_RS04285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQY74_RS04290	COG0156	8-amino-7-oxononanoate synthase activity
EQY74_RS04295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EQY74_RS04300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EQY74_RS04305	COG2124	cytochrome p450
EQY74_RS04315	COG0789	Transcriptional regulator
EQY74_RS04320	COG2814	Major facilitator Superfamily
EQY74_RS04325	COG0488	(ABC) transporter
EQY74_RS04330	COG0513	Belongs to the DEAD box helicase family
EQY74_RS04335	COG2130	NADP-dependent
EQY74_RS04350	COG0471	metal ion transport
EQY74_RS04370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS04380	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EQY74_RS04385	COG5658	integral membrane protein
EQY74_RS04390	COG0640	Transcriptional regulator
EQY74_RS04395	COG1254	Belongs to the acylphosphatase family
EQY74_RS04400	COG2258	MOSC domain
EQY74_RS04410	COG0024	Methionine aminopeptidase
EQY74_RS04415	COG1368	sulfuric ester hydrolase activity
EQY74_RS04425	COG1115	amino acid carrier protein
EQY74_RS04430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS04430	COG1263	PTS System
EQY74_RS04435	COG0366	Alpha amylase catalytic
EQY74_RS04440	COG2188	Transcriptional regulator
EQY74_RS04460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQY74_RS04465	COG1045	serine acetyltransferase
EQY74_RS04470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQY74_RS04480	COG1215	transferase activity, transferring glycosyl groups
EQY74_RS04485	COG0457	Tetratricopeptide repeat
EQY74_RS04485	COG0463	Glycosyl transferase, family 2
EQY74_RS04495	COG0673	inositol 2-dehydrogenase activity
EQY74_RS04505	COG0657	acetylesterase activity
EQY74_RS04510	COG1733	regulation of RNA biosynthetic process
EQY74_RS04515	COG0778	Nitroreductase
EQY74_RS04520	COG0737	Belongs to the 5'-nucleotidase family
EQY74_RS04525	COG0693	protein deglycase activity
EQY74_RS04530	COG4840	Belongs to the UPF0435 family
EQY74_RS04535	COG1115	amino acid carrier protein
EQY74_RS04540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQY74_RS04545	COG4980	gas vesicle protein
EQY74_RS04550	COG1295	ribonuclease BN
EQY74_RS04555	COG0477	Major facilitator Superfamily
EQY74_RS04565	COG0387	Pfam Sodium calcium exchanger
EQY74_RS04575	COG0535	radical SAM domain protein
EQY74_RS04585	COG0726	polysaccharide deacetylase
EQY74_RS04590	COG0371	Dehydrogenase
EQY74_RS04600	COG0598	Magnesium transport protein CorA
EQY74_RS04605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EQY74_RS04610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EQY74_RS04615	COG4637	Psort location Cytoplasmic, score
EQY74_RS04640	COG1819	glycosyl
EQY74_RS04650	COG0477	Major facilitator Superfamily
EQY74_RS04655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS04655	COG1263	PTS System
EQY74_RS04660	COG3711	transcriptional antiterminator
EQY74_RS04665	COG0288	reversible hydration of carbon dioxide
EQY74_RS04670	COG3002	Belongs to the UPF0753 family
EQY74_RS04675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQY74_RS04680	COG5609	conserved protein (DUF2294)
EQY74_RS04690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQY74_RS04695	COG0022	dehydrogenase e1 component
EQY74_RS04700	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQY74_RS04705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQY74_RS04710	COG3284	Transcriptional regulator
EQY74_RS04715	COG1742	UPF0060 membrane protein
EQY74_RS04720	COG1486	melibiose metabolic process
EQY74_RS04725	COG1737	Transcriptional regulator
EQY74_RS04730	COG1263	PTS System
EQY74_RS04730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS04745	COG1733	regulation of RNA biosynthetic process
EQY74_RS04750	COG2259	Doxx family
EQY74_RS04755	COG2514	catechol 2,3-dioxygenase activity
EQY74_RS04765	COG3507	Belongs to the glycosyl hydrolase 43 family
EQY74_RS04770	COG2207	Transcriptional regulator
EQY74_RS04770	COG1917	Cupin 2, conserved barrel domain protein
EQY74_RS04775	COG1653	transport
EQY74_RS04780	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS04785	COG1051	belongs to the nudix hydrolase family
EQY74_RS04795	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EQY74_RS04795	COG0392	lysyltransferase activity
EQY74_RS04800	COG0384	phenazine biosynthesis protein PhzF
EQY74_RS04805	COG0778	Nitroreductase
EQY74_RS04825	COG1090	epimerase
EQY74_RS04830	COG2137	regulation of response to DNA damage stimulus
EQY74_RS04860	COG0463	Glycosyl transferase, family 2
EQY74_RS04870	COG4485	Bacterial membrane protein, YfhO
EQY74_RS04875	COG1988	membrane-bound metal-dependent
EQY74_RS04880	COG1194	a g-specific adenine glycosylase
EQY74_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS04905	COG3557	Belongs to the UPF0374 family
EQY74_RS04910	COG1132	(ABC) transporter
EQY74_RS04915	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS04920	COG4608	Belongs to the ABC transporter superfamily
EQY74_RS04925	COG0747	negative chemotaxis
EQY74_RS04930	COG0601	transmembrane transport
EQY74_RS04935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS04940	COG4129	membrane
EQY74_RS04945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQY74_RS04950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EQY74_RS04955	COG0735	belongs to the Fur family
EQY74_RS05065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQY74_RS05075	COG0710	3-dehydroquinate dehydratase activity
EQY74_RS05080	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EQY74_RS05085	COG1116	anion transmembrane transporter activity
EQY74_RS05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQY74_RS05095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQY74_RS05100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQY74_RS05110	COG1476	TRANSCRIPTIONal
EQY74_RS05120	COG1131	(ABC) transporter
EQY74_RS05140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQY74_RS05150	COG3382	B3 4 domain protein
EQY74_RS05155	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EQY74_RS05165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EQY74_RS05170	COG0789	Transcriptional regulator
EQY74_RS05175	COG1664	Polymer-forming cytoskeletal
EQY74_RS05185	COG2766	serine protein kinase
EQY74_RS05190	COG2718	Belongs to the UPF0229 family
EQY74_RS05195	COG1566	PFAM secretion protein HlyD family protein
EQY74_RS05200	COG2814	Major facilitator Superfamily
EQY74_RS05205	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS05220	COG1131	(ABC) transporter
EQY74_RS05225	COG1131	(ABC) transporter
EQY74_RS05230	COG1131	(ABC) transporter
EQY74_RS05235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQY74_RS05240	COG1278	Cold shock
EQY74_RS05245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQY74_RS05250	COG2011	ABC-type metal ion transport system permease component
EQY74_RS05255	COG1464	Belongs to the NlpA lipoprotein family
EQY74_RS05260	COG1823	symporter activity
EQY74_RS05285	COG5577	PFAM Coat F domain
EQY74_RS05290	COG5002	protein histidine kinase activity
EQY74_RS05295	COG4085	toxin activity
EQY74_RS05295	COG1525	nuclease
EQY74_RS05295	COG0737	Belongs to the 5'-nucleotidase family
EQY74_RS05300	COG3764	Sortase (surface protein transpeptidase)
EQY74_RS05305	COG0564	pseudouridine synthase activity
EQY74_RS05315	COG0517	IMP dehydrogenase activity
EQY74_RS05320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EQY74_RS05325	COG3153	acetyltransferase
EQY74_RS05325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQY74_RS05330	COG0488	(ABC) transporter
EQY74_RS05340	COG2116	formate transmembrane transporter activity
EQY74_RS05345	COG0679	Auxin Efflux Carrier
EQY74_RS05350	COG0604	alcohol dehydrogenase
EQY74_RS05355	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EQY74_RS05360	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EQY74_RS05365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EQY74_RS05370	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EQY74_RS05375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EQY74_RS05390	COG2203	Gaf domain
EQY74_RS05390	COG4585	Histidine kinase
EQY74_RS05395	COG2197	response regulator
EQY74_RS05400	COG0431	NADPH-dependent FMN reductase
EQY74_RS05415	COG1959	2 iron, 2 sulfur cluster binding
EQY74_RS05420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EQY74_RS05420	COG1017	nitric oxide dioxygenase activity
EQY74_RS05425	COG2719	SpoVR family
EQY74_RS05430	COG1388	LysM domain
EQY74_RS05430	COG0791	NLP P60 protein
EQY74_RS05435	COG0583	DNA-binding transcription factor activity
EQY74_RS05440	COG0372	Belongs to the citrate synthase family
EQY74_RS05445	COG2133	pyrroloquinoline quinone binding
EQY74_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS05455	COG0733	neurotransmitter:sodium symporter activity
EQY74_RS05465	COG2207	Transcriptional regulator
EQY74_RS05465	COG3708	Transcriptional regulator
EQY74_RS05470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQY74_RS05490	COG1595	DNA-templated transcription, initiation
EQY74_RS05495	COG0662	Cupin 2, conserved barrel domain protein
EQY74_RS05505	COG0204	Acyl-transferase
EQY74_RS05510	COG3152	Membrane
EQY74_RS05520	COG1309	transcriptional regulator
EQY74_RS05525	COG1253	flavin adenine dinucleotide binding
EQY74_RS05530	COG0789	Transcriptional regulator
EQY74_RS05535	COG1253	flavin adenine dinucleotide binding
EQY74_RS05555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQY74_RS05560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EQY74_RS05565	COG0584	glycerophosphoryl diester phosphodiesterase
EQY74_RS05575	COG0668	transmembrane transport
EQY74_RS05580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EQY74_RS05595	COG0726	polysaccharide deacetylase
EQY74_RS05605	COG1757	Na H antiporter
EQY74_RS05610	COG2017	converts alpha-aldose to the beta-anomer
EQY74_RS05635	COG0589	response to stress
EQY74_RS05640	COG1132	(ABC) transporter
EQY74_RS05645	COG1132	(ABC) transporter
EQY74_RS05650	COG0702	epimerase
EQY74_RS05665	COG3842	ATPase activity
EQY74_RS05670	COG2508	Transcriptional regulator
EQY74_RS05680	COG0189	ligase activity
EQY74_RS05685	COG0189	ligase activity
EQY74_RS05690	COG4399	Belongs to the UPF0754 family
EQY74_RS05695	COG3679	Belongs to the UPF0342 family
EQY74_RS05705	COG0561	phosphatase activity
EQY74_RS05710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQY74_RS05715	COG0475	glutathione-regulated potassium exporter activity
EQY74_RS05720	COG0490	domain, Protein
EQY74_RS05730	COG1024	Enoyl-CoA hydratase
EQY74_RS05735	COG0457	Tetratricopeptide repeat
EQY74_RS05750	COG4152	abc transporter atp-binding protein
EQY74_RS05755	COG1668	transmembrane transport
EQY74_RS05760	COG0420	3'-5' exonuclease activity
EQY74_RS05770	COG3481	metal-dependent phosphohydrolase, HD sub domain
EQY74_RS05780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EQY74_RS05810	COG1846	Transcriptional regulator
EQY74_RS05815	COG4980	gas vesicle protein
EQY74_RS05830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EQY74_RS05835	COG0537	adenosine 5'-monophosphoramidase activity
EQY74_RS05845	COG1131	(ABC) transporter
EQY74_RS05850	COG4473	ABC transporter
EQY74_RS05860	COG1473	amidohydrolase
EQY74_RS05865	COG3069	C4-dicarboxylate transmembrane transporter activity
EQY74_RS05870	COG2329	Antibiotic biosynthesis monooxygenase
EQY74_RS05875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQY74_RS05880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EQY74_RS05885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EQY74_RS05890	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EQY74_RS05895	COG1309	transcriptional regulator
EQY74_RS05900	COG1511	domain protein
EQY74_RS05905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQY74_RS05910	COG1363	Peptidase, m42
EQY74_RS05920	COG1301	dicarboxylic acid transport
EQY74_RS05930	COG1234	tRNA 3'-trailer cleavage
EQY74_RS05935	COG0095	Lipoate-protein ligase
EQY74_RS05940	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS05950	COG1396	sequence-specific DNA binding
EQY74_RS05965	COG0501	Belongs to the peptidase M48B family
EQY74_RS05975	COG0697	spore germination
EQY74_RS05980	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EQY74_RS05990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS05995	COG0406	alpha-ribazole phosphatase activity
EQY74_RS06000	COG0840	transmembrane signaling receptor activity
EQY74_RS06005	COG0723	plastoquinol--plastocyanin reductase activity
EQY74_RS06005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQY74_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS06020	COG4903	ComK protein
EQY74_RS06030	COG0398	Pfam SNARE associated Golgi protein
EQY74_RS06035	COG0681	Belongs to the peptidase S26 family
EQY74_RS06040	COG1404	Belongs to the peptidase S8 family
EQY74_RS06050	COG2508	Transcriptional regulator
EQY74_RS06060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EQY74_RS06065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQY74_RS06070	COG3257	ureidoglycine aminohydrolase activity
EQY74_RS06075	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EQY74_RS06080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EQY74_RS06085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQY74_RS06090	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQY74_RS06100	COG0549	Belongs to the carbamate kinase family
EQY74_RS06105	COG2814	Major facilitator Superfamily
EQY74_RS06115	COG0457	Tetratricopeptide repeat
EQY74_RS06135	COG1609	Transcriptional regulator
EQY74_RS06140	COG1653	transport
EQY74_RS06145	COG1175	transmembrane transport
EQY74_RS06150	COG0395	ABC-type sugar transport system, permease component
EQY74_RS06155	COG1486	melibiose metabolic process
EQY74_RS06160	COG3180	Ammonia monooxygenase
EQY74_RS06175	COG3546	catalase activity
EQY74_RS06180	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS06185	COG2814	Major facilitator Superfamily
EQY74_RS06185	COG0477	Major facilitator Superfamily
EQY74_RS06195	COG5002	protein histidine kinase activity
EQY74_RS06200	COG0745	RESPONSE REGULATOR receiver
EQY74_RS06205	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EQY74_RS06210	COG0725	ABC transporter, periplasmic molybdate-binding protein
EQY74_RS06215	COG4149	molybdate abc transporter
EQY74_RS06220	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EQY74_RS06225	COG1074	ATP-dependent DNA helicase activity
EQY74_RS06230	COG0420	3'-5' exonuclease activity
EQY74_RS06235	COG0419	ATPase involved in DNA repair
EQY74_RS06280	COG5337	Spore coat protein CotH
EQY74_RS06290	COG0179	Fumarylacetoacetate (FAA) hydrolase
EQY74_RS06310	COG0367	asparagine synthase
EQY74_RS06325	COG0347	Belongs to the P(II) protein family
EQY74_RS06330	COG0534	Mate efflux family protein
EQY74_RS06335	COG1917	Cupin 2, conserved barrel domain protein
EQY74_RS06335	COG2207	Transcriptional regulator
EQY74_RS06345	COG1609	Transcriptional regulator
EQY74_RS06350	COG0673	inositol 2-dehydrogenase activity
EQY74_RS06355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQY74_RS06365	COG0076	glutamate decarboxylase activity
EQY74_RS06390	COG2153	protein acetylation
EQY74_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS06400	COG2378	regulation of single-species biofilm formation
EQY74_RS06405	COG0646	methionine synthase
EQY74_RS06405	COG1410	methionine synthase
EQY74_RS06410	COG0646	methionine synthase
EQY74_RS06410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EQY74_RS06415	COG1666	GTP binding
EQY74_RS06420	COG2996	Protein conserved in bacteria
EQY74_RS06435	COG1307	EDD domain protein, DegV family
EQY74_RS06440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS06450	COG0516	GMP reductase activity
EQY74_RS06460	COG0561	phosphatase activity
EQY74_RS06465	COG1073	alpha beta
EQY74_RS06470	COG2151	metal-sulfur cluster biosynthetic enzyme
EQY74_RS06480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EQY74_RS06485	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EQY74_RS06490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EQY74_RS06495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EQY74_RS06500	COG0505	Belongs to the CarA family
EQY74_RS06505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQY74_RS06510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQY74_RS06515	COG1968	undecaprenyl-diphosphatase activity
EQY74_RS06530	COG2267	carboxylic ester hydrolase activity
EQY74_RS06540	COG1744	ABC transporter substrate-binding protein PnrA-like
EQY74_RS06555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQY74_RS06560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EQY74_RS06565	COG5504	Zn-dependent protease
EQY74_RS06570	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS06585	COG0601	transmembrane transport
EQY74_RS06590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS06615	COG0180	Tryptophanyl-tRNA synthetase
EQY74_RS06625	COG4166	transmembrane transport
EQY74_RS06630	COG0601	transmembrane transport
EQY74_RS06635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS06640	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS06645	COG4608	Belongs to the ABC transporter superfamily
EQY74_RS06650	COG0456	acetyltransferase
EQY74_RS06655	COG1393	Belongs to the ArsC family
EQY74_RS06660	COG0861	Integral membrane protein TerC family
EQY74_RS06670	COG4862	establishment of competence for transformation
EQY74_RS06690	COG4565	transcriptional regulatory protein
EQY74_RS06695	COG3290	protein histidine kinase activity
EQY74_RS06700	COG4469	Competence protein
EQY74_RS06705	COG1164	Oligoendopeptidase f
EQY74_RS06710	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EQY74_RS06715	COG2346	COG2346, Truncated hemoglobins
EQY74_RS06720	COG0741	lytic transglycosylase activity
EQY74_RS06725	COG4116	CYTH
EQY74_RS06735	COG2357	RelA SpoT domain protein
EQY74_RS06740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQY74_RS06745	COG0564	pseudouridine synthase activity
EQY74_RS06750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EQY74_RS06760	COG0475	glutathione-regulated potassium exporter activity
EQY74_RS06760	COG0569	domain protein
EQY74_RS06765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQY74_RS06770	COG0352	thiamine-phosphate diphosphorylase activity
EQY74_RS06780	COG2104	thiamine diphosphate biosynthetic process
EQY74_RS06785	COG2022	thiamine diphosphate biosynthetic process
EQY74_RS06790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQY74_RS06795	COG0351	phosphomethylpyrimidine kinase
EQY74_RS06800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EQY74_RS06855	COG0210	DNA helicase
EQY74_RS06865	COG0586	Pfam SNARE associated Golgi protein
EQY74_RS06870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQY74_RS06875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQY74_RS06880	COG2246	polysaccharide biosynthetic process
EQY74_RS06885	COG2153	protein acetylation
EQY74_RS06890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQY74_RS06895	COG2382	esterase
EQY74_RS06915	COG0626	cystathionine gamma-synthase activity
EQY74_RS06920	COG0626	cystathionine gamma-synthase activity
EQY74_RS06925	COG5505	Protein of unknown function (DUF819)
EQY74_RS06940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQY74_RS06945	COG3507	Belongs to the glycosyl hydrolase 43 family
EQY74_RS06965	COG0110	maltose O-acetyltransferase activity
EQY74_RS06975	COG0583	DNA-binding transcription factor activity
EQY74_RS06980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQY74_RS06985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EQY74_RS06995	COG0583	DNA-binding transcription factor activity
EQY74_RS07000	COG0697	spore germination
EQY74_RS07005	COG0346	lactoylglutathione lyase activity
EQY74_RS07015	COG1388	LysM domain
EQY74_RS07015	COG3584	3D domain protein
EQY74_RS07020	COG2814	Major facilitator Superfamily
EQY74_RS07025	COG1309	transcriptional regulator
EQY74_RS07045	COG5444	nuclease activity
EQY74_RS07050	COG4195	phage-related replication protein
EQY74_RS07055	COG2856	Zn peptidase
EQY74_RS07060	COG1396	sequence-specific DNA binding
EQY74_RS07075	COG1522	sequence-specific DNA binding
EQY74_RS07080	COG1484	DNA-dependent DNA replication
EQY74_RS07095	COG1595	DNA-templated transcription, initiation
EQY74_RS07100	COG3728	DNA packaging
EQY74_RS07100	COG5484	DNA packaging
EQY74_RS07105	COG1783	phage Terminase large subunit
EQY74_RS07115	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EQY74_RS07120	COG4653	Phage capsid family
EQY74_RS07170	COG5412	phage tail tape measure protein
EQY74_RS07170	COG3953	SLT domain
EQY74_RS07175	COG1652	LysM domain
EQY74_RS07180	COG4193	domain, Protein
EQY74_RS07190	COG3628	GPW Gp25 family protein
EQY74_RS07195	COG3299	homolog of phage Mu protein gp47
EQY74_RS07200	COG3778	Protein conserved in bacteria
EQY74_RS07235	COG1802	Transcriptional regulator
EQY74_RS07240	COG1063	alcohol dehydrogenase
EQY74_RS07245	COG1312	Catalyzes the dehydration of D-mannonate
EQY74_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS07255	COG1063	alcohol dehydrogenase
EQY74_RS07260	COG2271	Major facilitator Superfamily
EQY74_RS07275	COG0306	phosphate transporter
EQY74_RS07280	COG1392	Phosphate transport regulator
EQY74_RS07285	COG0405	Gamma-glutamyltransferase
EQY74_RS07290	COG5578	integral membrane protein
EQY74_RS07295	COG2972	Histidine kinase
EQY74_RS07300	COG4753	response regulator
EQY74_RS07300	COG2207	Transcriptional regulator
EQY74_RS07305	COG1653	transport
EQY74_RS07310	COG1175	transmembrane transport
EQY74_RS07315	COG0395	ABC-type sugar transport system, permease component
EQY74_RS07320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQY74_RS07325	COG2207	Transcriptional regulator
EQY74_RS07330	COG2755	lipolytic protein G-D-S-L family
EQY74_RS07340	COG5578	integral membrane protein
EQY74_RS07345	COG3401	FG-GAP repeat protein
EQY74_RS07355	COG2755	lipolytic protein G-D-S-L family
EQY74_RS07360	COG3401	FG-GAP repeat protein
EQY74_RS07365	COG0667	Aldo Keto reductase
EQY74_RS07370	COG2755	lipolytic protein G-D-S-L family
EQY74_RS07375	COG1874	Beta-galactosidase
EQY74_RS07385	COG1653	transport
EQY74_RS07390	COG4209	transmembrane transport
EQY74_RS07395	COG0395	ABC-type sugar transport system, permease component
EQY74_RS07400	COG0531	amino acid
EQY74_RS07405	COG0346	lactoylglutathione lyase activity
EQY74_RS07415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQY74_RS07420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQY74_RS07425	COG2362	D-Aminopeptidase
EQY74_RS07430	COG0601	transmembrane transport
EQY74_RS07435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS07440	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS07445	COG4166	transmembrane transport
EQY74_RS07450	COG1619	proteins homologs of microcin C7 resistance protein MccF
EQY74_RS07460	COG0791	NLP P60 protein
EQY74_RS07465	COG4608	Belongs to the ABC transporter superfamily
EQY74_RS07470	COG1834	amidinotransferase
EQY74_RS07475	COG1607	acyl-coa hydrolase
EQY74_RS07485	COG3866	Pectate lyase
EQY74_RS07505	COG2318	DinB family
EQY74_RS07510	COG2076	Multidrug Resistance protein
EQY74_RS07515	COG2076	Multidrug Resistance protein
EQY74_RS07520	COG0788	formyltetrahydrofolate deformylase activity
EQY74_RS07525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQY74_RS07530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQY74_RS07535	COG1764	response to oxidative stress
EQY74_RS07540	COG1846	Transcriptional regulator
EQY74_RS07545	COG1764	response to oxidative stress
EQY74_RS07555	COG0590	tRNA wobble adenosine to inosine editing
EQY74_RS07560	COG0406	alpha-ribazole phosphatase activity
EQY74_RS07575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQY74_RS07580	COG1404	Belongs to the peptidase S8 family
EQY74_RS07590	COG2239	Acts as a magnesium transporter
EQY74_RS07600	COG0582	viral genome integration into host DNA
EQY74_RS07605	COG2856	Zn peptidase
EQY74_RS07620	COG3620	sequence-specific DNA binding
EQY74_RS07635	COG3646	Phage regulatory protein
EQY74_RS07635	COG3645	SOS response
EQY74_RS07675	COG1484	DNA-dependent DNA replication
EQY74_RS07710	COG3331	DNA recombination
EQY74_RS07725	COG0629	single-stranded DNA binding
EQY74_RS07785	COG5484	DNA packaging
EQY74_RS07785	COG3728	DNA packaging
EQY74_RS07790	COG1783	phage Terminase large subunit
EQY74_RS07915	COG5444	nuclease activity
EQY74_RS07935	COG0789	Transcriptional regulator
EQY74_RS07950	COG1846	Transcriptional regulator
EQY74_RS07955	COG1793	dna ligase
EQY74_RS07955	COG3285	dna ligase
EQY74_RS07960	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EQY74_RS07965	COG3300	MHYT domain
EQY74_RS07965	COG5001	Diguanylate cyclase
EQY74_RS07970	COG0586	Pfam SNARE associated Golgi protein
EQY74_RS07975	COG0861	Integral membrane protein TerC family
EQY74_RS07980	COG1191	sigma factor activity
EQY74_RS08000	COG0501	Belongs to the peptidase M48B family
EQY74_RS08005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQY74_RS08015	COG0768	penicillin binding
EQY74_RS08030	COG3594	Acyltransferase
EQY74_RS08035	COG5002	protein histidine kinase activity
EQY74_RS08040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQY74_RS08045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EQY74_RS08050	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EQY74_RS08055	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EQY74_RS08060	COG0436	Aminotransferase
EQY74_RS08065	COG1850	ribulose-bisphosphate carboxylase activity
EQY74_RS08070	COG0235	Class ii aldolase
EQY74_RS08070	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EQY74_RS08075	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EQY74_RS08080	COG0346	lactoylglutathione lyase activity
EQY74_RS08085	COG3339	Conserved Protein
EQY74_RS08095	COG3852	Histidine kinase
EQY74_RS08100	COG1846	Transcriptional regulator
EQY74_RS08105	COG1360	Flagellar Motor Protein
EQY74_RS08110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EQY74_RS08115	COG0542	response to heat
EQY74_RS08120	COG3949	Membrane
EQY74_RS08125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EQY74_RS08130	COG0720	synthase
EQY74_RS08135	COG0602	queuosine metabolic process
EQY74_RS08140	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EQY74_RS08150	COG4974	Belongs to the 'phage' integrase family
EQY74_RS08200	COG5444	nuclease activity
EQY74_RS08285	COG0582	viral genome integration into host DNA
EQY74_RS08405	COG1388	LysM domain
EQY74_RS08405	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS08405	COG3409	Peptidoglycan-binding domain 1 protein
EQY74_RS08430	COG0582	viral genome integration into host DNA
EQY74_RS08445	COG3739	integral membrane protein
EQY74_RS08450	COG3655	Transcriptional regulator
EQY74_RS08485	COG4873	Protein conserved in bacteria
EQY74_RS08495	COG3773	Cell wall hydrolase
EQY74_RS08500	COG2244	polysaccharide biosynthetic process
EQY74_RS08505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS08510	COG2217	Heavy metal translocating P-type atpase
EQY74_RS08515	COG0006	proline dipeptidase activity
EQY74_RS08525	COG1609	Transcriptional regulator
EQY74_RS08530	COG3711	transcriptional antiterminator
EQY74_RS08535	COG2190	(PTS) system
EQY74_RS08535	COG1263	PTS System
EQY74_RS08535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS08540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS08545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EQY74_RS08555	COG1533	DNA photolyase activity
EQY74_RS08560	COG0456	acetyltransferase
EQY74_RS08565	COG0840	transmembrane signaling receptor activity
EQY74_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS08575	COG2084	Dehydrogenase
EQY74_RS08580	COG2340	Cysteine-rich secretory protein family
EQY74_RS08595	COG4191	Histidine kinase
EQY74_RS08600	COG0436	Aminotransferase
EQY74_RS08605	COG1714	RDD family
EQY74_RS08615	COG0835	chemotaxis
EQY74_RS08615	COG0784	Response regulator, receiver
EQY74_RS08625	COG2814	Major facilitator Superfamily
EQY74_RS08630	COG1376	ErfK ybiS ycfS ynhG family protein
EQY74_RS08640	COG1408	metallophosphoesterase
EQY74_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS08650	COG2200	EAL domain
EQY74_RS08660	COG4703	Protein of unknown function (DUF1797)
EQY74_RS08665	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EQY74_RS08675	COG0517	IMP dehydrogenase activity
EQY74_RS08680	COG0583	DNA-binding transcription factor activity
EQY74_RS08685	COG0716	FMN binding
EQY74_RS08695	COG0716	FMN binding
EQY74_RS08700	COG2171	N-acyltransferase activity
EQY74_RS08705	COG1473	amidohydrolase
EQY74_RS08715	COG0450	alkyl hydroperoxide reductase
EQY74_RS08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS08735	COG0746	molybdenum cofactor guanylyltransferase activity
EQY74_RS08740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EQY74_RS08745	COG0303	'Molybdopterin
EQY74_RS08750	COG1763	Mo-molybdopterin cofactor biosynthetic process
EQY74_RS08755	COG0314	molybdopterin synthase activity
EQY74_RS08760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EQY74_RS08770	COG1132	(ABC) transporter
EQY74_RS08775	COG1132	(ABC) transporter
EQY74_RS08785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EQY74_RS08790	COG1136	(ABC) transporter
EQY74_RS08795	COG0577	efflux transmembrane transporter activity
EQY74_RS08800	COG1349	DNA-binding transcription factor activity
EQY74_RS08805	COG1105	Belongs to the carbohydrate kinase PfkB family
EQY74_RS08810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS08810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS08810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS08830	COG0488	(ABC) transporter
EQY74_RS08840	COG2309	aminopeptidase activity
EQY74_RS08850	COG1077	Cell shape determining protein MreB Mrl
EQY74_RS08855	COG2002	toxin-antitoxin pair type II binding
EQY74_RS08860	COG3852	Histidine kinase
EQY74_RS08865	COG0569	domain protein
EQY74_RS08870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EQY74_RS08875	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQY74_RS08880	COG5503	Protein of unknown function (DUF1447)
EQY74_RS08885	COG0561	phosphatase activity
EQY74_RS08895	COG0242	peptide deformylase activity
EQY74_RS08905	COG0497	DNA recombination
EQY74_RS08910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQY74_RS08915	COG0022	dehydrogenase e1 component
EQY74_RS08920	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQY74_RS08925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQY74_RS08930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS08940	COG1982	Orn Lys Arg decarboxylase major
EQY74_RS08950	COG4476	Belongs to the UPF0223 family
EQY74_RS08955	COG4493	Belongs to the UPF0637 family
EQY74_RS08965	COG0483	inositol monophosphate 1-phosphatase activity
EQY74_RS08985	COG1595	DNA-templated transcription, initiation
EQY74_RS09000	COG1217	gtp-binding protein TYPA
EQY74_RS09010	COG1846	Transcriptional regulator
EQY74_RS09015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EQY74_RS09020	COG4896	Protein conserved in bacteria
EQY74_RS09030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EQY74_RS09035	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQY74_RS09040	COG2066	Belongs to the glutaminase family
EQY74_RS09045	COG4838	Belongs to the UPF0358 family
EQY74_RS09050	COG0772	Belongs to the SEDS family
EQY74_RS09055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EQY74_RS09060	COG1612	heme a metabolic process
EQY74_RS09065	COG0109	protoheme IX farnesyltransferase activity
EQY74_RS09070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQY74_RS09070	COG2010	Cytochrome c
EQY74_RS09075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQY74_RS09080	COG1845	cytochrome c oxidase, subunit III
EQY74_RS09085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQY74_RS09090	COG3336	cytochrome c oxidase
EQY74_RS09100	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EQY74_RS09105	COG2340	Cysteine-rich secretory protein family
EQY74_RS09120	COG3679	Belongs to the UPF0342 family
EQY74_RS09125	COG4471	UPF0298 protein
EQY74_RS09130	COG0742	ribosomal rna small subunit methyltransferase
EQY74_RS09135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EQY74_RS09140	COG3314	Sporulation integral membrane protein YlbJ
EQY74_RS09145	COG3480	Lon protease (S16) C-terminal proteolytic domain
EQY74_RS09150	COG1323	Belongs to the UPF0348 family
EQY74_RS09155	COG1399	metal-binding, possibly nucleic acid-binding protein
EQY74_RS09160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EQY74_RS09170	COG0454	-acetyltransferase
EQY74_RS09175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EQY74_RS09180	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EQY74_RS09185	COG2001	Belongs to the MraZ family
EQY74_RS09190	COG0275	rRNA processing
EQY74_RS09195	COG4839	cell division protein FtsL
EQY74_RS09200	COG0768	penicillin binding
EQY74_RS09205	COG0768	penicillin binding
EQY74_RS09210	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EQY74_RS09215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQY74_RS09220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQY74_RS09225	COG0772	Belongs to the SEDS family
EQY74_RS09230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQY74_RS09235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EQY74_RS09240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EQY74_RS09245	COG3879	Bacterial protein of unknown function (DUF881)
EQY74_RS09250	COG3879	Bacterial protein of unknown function (DUF881)
EQY74_RS09255	COG3856	small basic protein
EQY74_RS09260	COG0849	cell division
EQY74_RS09265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EQY74_RS09275	COG4412	M6 family metalloprotease domain protein
EQY74_RS09275	COG1404	Belongs to the peptidase S8 family
EQY74_RS09280	COG4412	M6 family metalloprotease domain protein
EQY74_RS09280	COG1404	Belongs to the peptidase S8 family
EQY74_RS09290	COG1191	sigma factor activity
EQY74_RS09295	COG1191	sigma factor activity
EQY74_RS09300	COG1119	ATPase activity
EQY74_RS09305	COG0500	methyltransferase
EQY74_RS09310	COG1873	PFAM PRC-barrel domain
EQY74_RS09315	COG1496	oxidoreductase activity
EQY74_RS09320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EQY74_RS09325	COG1799	cell septum assembly
EQY74_RS09330	COG0762	integral membrane protein
EQY74_RS09335	COG2302	S4 RNA-binding domain
EQY74_RS09340	COG3599	regulation of cell shape
EQY74_RS09345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EQY74_RS09350	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQY74_RS09355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EQY74_RS09360	COG0564	pseudouridine synthase activity
EQY74_RS09365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EQY74_RS09370	COG2233	PERMEase
EQY74_RS09375	COG0540	Belongs to the ATCase OTCase family
EQY74_RS09380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EQY74_RS09385	COG0505	Belongs to the CarA family
EQY74_RS09390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EQY74_RS09395	COG0543	2 iron, 2 sulfur cluster binding
EQY74_RS09400	COG0167	dihydroorotate dehydrogenase activity
EQY74_RS09405	COG0284	orotidine-5'-phosphate decarboxylase activity
EQY74_RS09410	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EQY74_RS09420	COG0175	sulfate reduction
EQY74_RS09425	COG0306	phosphate transporter
EQY74_RS09430	COG2046	Belongs to the sulfate adenylyltransferase family
EQY74_RS09435	COG0529	Catalyzes the synthesis of activated sulfate
EQY74_RS09440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EQY74_RS09445	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
EQY74_RS09450	COG1648	precorrin-2 dehydrogenase activity
EQY74_RS09460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EQY74_RS09465	COG1561	YicC-like family, N-terminal region
EQY74_RS09470	COG2052	Domain of unknown function (DUF370)
EQY74_RS09475	COG0194	GDP metabolic process
EQY74_RS09480	COG1758	RNA polymerase activity
EQY74_RS09485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQY74_RS09490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EQY74_RS09495	COG0242	peptide deformylase activity
EQY74_RS09500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EQY74_RS09505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQY74_RS09505	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EQY74_RS09510	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EQY74_RS09515	COG0631	protein serine/threonine phosphatase activity
EQY74_RS09520	COG2815	serine threonine protein kinase
EQY74_RS09520	COG0515	serine threonine protein kinase
EQY74_RS09525	COG1162	GTPase activity
EQY74_RS09530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EQY74_RS09535	COG1564	THIamine pyrophosphokinase
EQY74_RS09545	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EQY74_RS09550	COG1302	Protein conserved in bacteria
EQY74_RS09555	COG1461	Dihydroxyacetone kinase
EQY74_RS09560	COG1760	l-serine dehydratase
EQY74_RS09565	COG1760	l-serine dehydratase
EQY74_RS09570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EQY74_RS09575	COG1349	DNA-binding transcription factor activity
EQY74_RS09580	COG0416	fatty acid biosynthetic process
EQY74_RS09585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EQY74_RS09590	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS09595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQY74_RS09600	COG0571	ribonuclease III activity
EQY74_RS09605	COG1196	nuclear chromosome segregation
EQY74_RS09610	COG0552	protein localization to endoplasmic reticulum
EQY74_RS09615	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EQY74_RS09620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EQY74_RS09625	COG0228	four-way junction DNA binding
EQY74_RS09630	COG1837	Belongs to the UPF0109 family
EQY74_RS09640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EQY74_RS09645	COG0336	Belongs to the RNA methyltransferase TrmD family
EQY74_RS09650	COG0335	large ribosomal subunit rRNA binding
EQY74_RS09655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQY74_RS09660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQY74_RS09670	COG2257	FlhB HrpN YscU SpaS Family
EQY74_RS09675	COG0045	succinate-CoA ligase (ADP-forming) activity
EQY74_RS09680	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EQY74_RS09685	COG0758	DNA mediated transformation
EQY74_RS09690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EQY74_RS09695	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EQY74_RS09700	COG4974	Belongs to the 'phage' integrase family
EQY74_RS09705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EQY74_RS09710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EQY74_RS09715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQY74_RS09720	COG1815	bacterial-type flagellum-dependent cell motility
EQY74_RS09725	COG1558	bacterial-type flagellum-dependent cell motility
EQY74_RS09730	COG1677	Flagellar hook-basal body complex protein FliE
EQY74_RS09735	COG1766	The M ring may be actively involved in energy transduction
EQY74_RS09740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQY74_RS09745	COG1317	bacterial-type flagellum organization
EQY74_RS09750	COG1157	protein secretion by the type III secretion system
EQY74_RS09755	COG2882	bacterial-type flagellum organization
EQY74_RS09765	COG3144	bacterial-type flagellum assembly
EQY74_RS09770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EQY74_RS09775	COG4786	Flagellar basal body rod
EQY74_RS09780	COG1582	Flagellar protein (FlbD)
EQY74_RS09785	COG1580	Controls the rotational direction of flagella during chemotaxis
EQY74_RS09790	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQY74_RS09795	COG1776	CheC inhibitor of MCP methylation
EQY74_RS09795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EQY74_RS09800	COG2201	protein-glutamate methylesterase activity
EQY74_RS09805	COG3190	flagellar
EQY74_RS09810	COG1338	Plays a role in the flagellum-specific transport system
EQY74_RS09815	COG1987	bacterial-type flagellum assembly
EQY74_RS09820	COG1684	flagellar biosynthetic protein fliR
EQY74_RS09825	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQY74_RS09830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EQY74_RS09835	COG1419	protein localization to endoplasmic reticulum
EQY74_RS09840	COG0455	bacterial-type flagellum organization
EQY74_RS09845	COG2201	protein-glutamate methylesterase activity
EQY74_RS09850	COG2198	Histidine kinase
EQY74_RS09850	COG0643	Histidine kinase
EQY74_RS09855	COG0835	chemotaxis
EQY74_RS09860	COG1776	CheC inhibitor of MCP methylation
EQY74_RS09865	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EQY74_RS09870	COG1191	sigma factor activity
EQY74_RS09880	COG0052	Belongs to the universal ribosomal protein uS2 family
EQY74_RS09885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EQY74_RS09890	COG0528	UMP kinase activity
EQY74_RS09895	COG0233	cytoplasmic translational termination
EQY74_RS09900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EQY74_RS09905	COG4589	Belongs to the CDS family
EQY74_RS09910	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EQY74_RS09915	COG0750	zinc metalloprotease
EQY74_RS09920	COG0442	prolyl-tRNA aminoacylation
EQY74_RS09925	COG2176	DNA-directed DNA polymerase activity
EQY74_RS09955	COG0779	Required for maturation of 30S ribosomal subunits
EQY74_RS09960	COG0195	Participates in both transcription termination and antitermination
EQY74_RS09965	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EQY74_RS09970	COG1358	cellular component organization or biogenesis
EQY74_RS09975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EQY74_RS09980	COG1550	Protein conserved in bacteria
EQY74_RS09985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EQY74_RS09990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EQY74_RS09995	COG0196	riboflavin kinase activity
EQY74_RS10000	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EQY74_RS10005	COG1185	polyribonucleotide nucleotidyltransferase activity
EQY74_RS10010	COG0726	polysaccharide deacetylase
EQY74_RS10015	COG0612	Peptidase, M16
EQY74_RS10020	COG1873	PFAM PRC-barrel domain
EQY74_RS10025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQY74_RS10030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EQY74_RS10035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EQY74_RS10040	COG0527	aspartate kinase activity
EQY74_RS10050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EQY74_RS10055	COG0740	serine-type endopeptidase activity
EQY74_RS10065	COG4980	gas vesicle protein
EQY74_RS10065	COG1674	ftsk spoiiie
EQY74_RS10070	COG2188	Transcriptional regulator
EQY74_RS10075	COG2814	Major facilitator Superfamily
EQY74_RS10080	COG0612	Peptidase, M16
EQY74_RS10085	COG0612	Peptidase, M16
EQY74_RS10090	COG0300	oxidoreductase activity
EQY74_RS10105	COG1426	Protein conserved in bacteria
EQY74_RS10110	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EQY74_RS10115	COG1058	Belongs to the CinA family
EQY74_RS10115	COG1546	Belongs to the CinA family
EQY74_RS10125	COG1418	mRNA catabolic process
EQY74_RS10130	COG1692	metallophosphoesterase
EQY74_RS10135	COG2359	stage V sporulation protein S
EQY74_RS10145	COG1063	alcohol dehydrogenase
EQY74_RS10155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQY74_RS10160	COG4550	Control of competence regulator ComK, YlbF/YmcA
EQY74_RS10170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EQY74_RS10175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EQY74_RS10180	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EQY74_RS10185	COG5444	nuclease activity
EQY74_RS10205	COG0523	cobalamin synthesis protein
EQY74_RS10215	COG1247	-acetyltransferase
EQY74_RS10230	COG1231	oxidoreductase activity
EQY74_RS10235	COG3619	membrane
EQY74_RS10240	COG3263	regulation of cellular component size
EQY74_RS10260	COG0393	Putative heavy-metal-binding
EQY74_RS10265	COG0398	Pfam SNARE associated Golgi protein
EQY74_RS10270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EQY74_RS10275	COG1819	glycosyl
EQY74_RS10280	COG0531	amino acid
EQY74_RS10285	COG5577	PFAM Coat F domain
EQY74_RS10300	COG1309	transcriptional regulator
EQY74_RS10305	COG3631	Ketosteroid isomerase-related protein
EQY74_RS10310	COG0702	epimerase
EQY74_RS10320	COG1764	response to oxidative stress
EQY74_RS10325	COG2076	Multidrug Resistance protein
EQY74_RS10330	COG2076	Multidrug Resistance protein
EQY74_RS10345	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EQY74_RS10350	COG1923	regulation of RNA biosynthetic process
EQY74_RS10365	COG1780	Probably involved in ribonucleotide reductase function
EQY74_RS10370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQY74_RS10375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQY74_RS10380	COG4112	unkown
EQY74_RS10395	COG0735	belongs to the Fur family
EQY74_RS10400	COG1802	Transcriptional regulator
EQY74_RS10405	COG0697	spore germination
EQY74_RS10440	COG1309	transcriptional regulator
EQY74_RS10490	COG0464	growth
EQY74_RS10495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EQY74_RS10500	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EQY74_RS10505	COG0789	Transcriptional regulator
EQY74_RS10510	COG0174	glutamine synthetase
EQY74_RS10595	COG0490	domain, Protein
EQY74_RS10600	COG0475	glutathione-regulated potassium exporter activity
EQY74_RS10645	COG1309	transcriptional regulator
EQY74_RS10650	COG2076	Multidrug Resistance protein
EQY74_RS10655	COG2076	Multidrug Resistance protein
EQY74_RS10660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQY74_RS10680	COG3546	catalase activity
EQY74_RS10700	COG1846	Transcriptional regulator
EQY74_RS10705	COG0778	Nitroreductase
EQY74_RS10710	COG0346	lactoylglutathione lyase activity
EQY74_RS10715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQY74_RS10720	COG0655	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS10740	COG3209	COG3209 Rhs family protein
EQY74_RS10745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EQY74_RS10750	COG1388	LysM domain
EQY74_RS10755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQY74_RS10760	COG4224	UPF0291 protein
EQY74_RS10765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EQY74_RS10775	COG3763	UPF0154 protein
EQY74_RS10785	COG0785	Cytochrome C biogenesis protein
EQY74_RS10790	COG2201	protein-glutamate methylesterase activity
EQY74_RS10795	COG4846	Membrane protein involved in cytochrome C biogenesis
EQY74_RS10805	COG0071	Belongs to the small heat shock protein (HSP20) family
EQY74_RS10820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EQY74_RS10825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS10845	COG0824	Thioesterase
EQY74_RS10870	COG4841	protein insertion into membrane
EQY74_RS10875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EQY74_RS10880	COG1832	CoA-binding protein
EQY74_RS10885	COG0187	DNA topoisomerase II activity
EQY74_RS10890	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EQY74_RS10895	COG1609	Transcriptional regulator
EQY74_RS10910	COG2160	L-arabinose isomerase activity
EQY74_RS10930	COG1115	amino acid carrier protein
EQY74_RS10940	COG2181	nitrate reductase activity
EQY74_RS10945	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EQY74_RS10950	COG1140	nitrate reductase beta subunit
EQY74_RS10955	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EQY74_RS10970	COG0535	radical SAM domain protein
EQY74_RS10975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQY74_RS10985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EQY74_RS10990	COG2223	nitrite transmembrane transporter activity
EQY74_RS11010	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EQY74_RS11030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQY74_RS11040	COG0492	ferredoxin-NADP+ reductase activity
EQY74_RS11055	COG3420	alginic acid biosynthetic process
EQY74_RS11060	COG1114	Component of the transport system for branched-chain amino acids
EQY74_RS11065	COG1064	alcohol dehydrogenase
EQY74_RS11070	COG0789	Transcriptional regulator
EQY74_RS11095	COG1024	Enoyl-CoA hydratase
EQY74_RS11100	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS11105	COG2084	Dehydrogenase
EQY74_RS11110	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS11115	COG1482	cell wall glycoprotein biosynthetic process
EQY74_RS11120	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS11120	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS11120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS11145	COG3711	transcriptional antiterminator
EQY74_RS11145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS11160	COG1725	Transcriptional regulator
EQY74_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS11170	COG1312	Catalyzes the dehydration of D-mannonate
EQY74_RS11185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EQY74_RS11195	COG1609	Transcriptional regulator
EQY74_RS11200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQY74_RS11205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EQY74_RS11210	COG0640	Transcriptional regulator
EQY74_RS11220	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
EQY74_RS11235	COG1649	PFAM Uncharacterised BCR, COG1649
EQY74_RS11240	COG2404	hydrolase activity, acting on ester bonds
EQY74_RS11245	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EQY74_RS11255	COG2027	D-alanyl-D-alanine carboxypeptidase
EQY74_RS11260	COG1252	NADH dehydrogenase
EQY74_RS11275	COG0166	Belongs to the GPI family
EQY74_RS11285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQY74_RS11290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQY74_RS11295	COG1024	Enoyl-CoA hydratase
EQY74_RS11300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQY74_RS11305	COG0511	ligase activity, forming carbon-carbon bonds
EQY74_RS11310	COG0439	Biotin carboxylase
EQY74_RS11315	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS11320	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS11325	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS11330	COG1733	regulation of RNA biosynthetic process
EQY74_RS11335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EQY74_RS11340	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EQY74_RS11350	COG2323	membrane
EQY74_RS11360	COG0306	phosphate transporter
EQY74_RS11365	COG0175	sulfate reduction
EQY74_RS11370	COG1809	phosphosulfolactate synthase activity
EQY74_RS11375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS11380	COG4948	Mandelate Racemase Muconate Lactonizing
EQY74_RS11385	COG2814	Major facilitator Superfamily
EQY74_RS11390	COG0463	Glycosyl transferase, family 2
EQY74_RS11405	COG0493	'glutamate synthase
EQY74_RS11410	COG0070	glutamate synthase
EQY74_RS11410	COG0067	glutamate synthase
EQY74_RS11410	COG0069	glutamate synthase activity
EQY74_RS11415	COG0583	DNA-binding transcription factor activity
EQY74_RS11435	COG1846	Transcriptional regulator
EQY74_RS11445	COG1132	(ABC) transporter
EQY74_RS11455	COG0300	oxidoreductase activity
EQY74_RS11460	COG0574	Belongs to the PEP-utilizing enzyme family
EQY74_RS11460	COG3848	Pyruvate phosphate dikinase
EQY74_RS11470	COG0477	Major facilitator Superfamily
EQY74_RS11475	COG0243	molybdopterin cofactor binding
EQY74_RS11480	COG1846	Transcriptional regulator
EQY74_RS11490	COG0531	amino acid
EQY74_RS11500	COG0531	amino acid
EQY74_RS11510	COG0697	spore germination
EQY74_RS11515	COG0488	(ABC) transporter
EQY74_RS11520	COG0840	transmembrane signaling receptor activity
EQY74_RS11525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQY74_RS11530	COG1404	Belongs to the peptidase S8 family
EQY74_RS11540	COG1309	transcriptional regulator
EQY74_RS11545	COG1846	Transcriptional regulator
EQY74_RS11575	COG1309	transcriptional regulator
EQY74_RS11580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS11585	COG3708	Transcriptional regulator
EQY74_RS11595	COG2378	regulation of single-species biofilm formation
EQY74_RS11605	COG0640	Transcriptional regulator
EQY74_RS11620	COG0531	amino acid
EQY74_RS11625	COG0741	lytic transglycosylase activity
EQY74_RS11630	COG1086	Polysaccharide biosynthesis protein
EQY74_RS11650	COG2322	membrane
EQY74_RS11665	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS11670	COG3584	3D domain protein
EQY74_RS11670	COG1388	LysM domain
EQY74_RS11675	COG0514	ATP-dependent DNA helicase (RecQ)
EQY74_RS11695	COG2315	Protein conserved in bacteria
EQY74_RS11715	COG2427	Protein of unknown function (DUF1641)
EQY74_RS11740	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
EQY74_RS11785	COG0402	S-adenosylhomocysteine deaminase activity
EQY74_RS11815	COG1280	lysine exporter protein (LysE YggA)
EQY74_RS11820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EQY74_RS11830	COG0574	Belongs to the PEP-utilizing enzyme family
EQY74_RS11830	COG3848	Pyruvate phosphate dikinase
EQY74_RS11835	COG1309	transcriptional regulator
EQY74_RS11850	COG2318	DinB family
EQY74_RS11855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQY74_RS11860	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQY74_RS11875	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS11880	COG2814	Major facilitator Superfamily
EQY74_RS11895	COG1657	PFAM Prenyltransferase squalene oxidase
EQY74_RS11900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQY74_RS11910	COG0733	neurotransmitter:sodium symporter activity
EQY74_RS11920	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQY74_RS11925	COG0567	Dehydrogenase, E1 component
EQY74_RS11930	COG4548	von Willebrand factor, type A
EQY74_RS11935	COG0714	Associated with various cellular activities
EQY74_RS11940	COG2032	superoxide dismutase activity
EQY74_RS11945	COG1388	LysM domain
EQY74_RS11945	COG0791	NLP P60 protein
EQY74_RS11955	COG0534	Mate efflux family protein
EQY74_RS11960	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQY74_RS11965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQY74_RS11975	COG2962	Rard protein
EQY74_RS11985	COG4305	rare lipoprotein A
EQY74_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS12000	COG1733	regulation of RNA biosynthetic process
EQY74_RS12005	COG0778	Nitroreductase
EQY74_RS12010	COG0400	carboxylic ester hydrolase activity
EQY74_RS12020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS12030	COG0793	Belongs to the peptidase S41A family
EQY74_RS12030	COG3409	Peptidoglycan-binding domain 1 protein
EQY74_RS12035	COG2226	methyltransferase
EQY74_RS12045	COG1876	peptidase activity
EQY74_RS12050	COG0813	purine-nucleoside phosphorylase activity
EQY74_RS12055	COG0701	Predicted permease
EQY74_RS12075	COG0671	phosphoesterase, PA-phosphatase related
EQY74_RS12090	COG4479	Belongs to the UPF0346 family
EQY74_RS12110	COG3331	DNA recombination
EQY74_RS12120	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EQY74_RS12145	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQY74_RS12170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EQY74_RS12185	COG0756	dUTP diphosphatase activity
EQY74_RS12195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS12205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQY74_RS12210	COG1372	Participates in initiation and elongation during chromosome replication
EQY74_RS12210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQY74_RS12215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EQY74_RS12220	COG1780	Probably involved in ribonucleotide reductase function
EQY74_RS12290	COG3584	3D domain protein
EQY74_RS12295	COG0587	DNA-directed DNA polymerase activity
EQY74_RS12315	COG0587	DNA-directed DNA polymerase activity
EQY74_RS12320	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQY74_RS12325	COG0358	DNA primase activity
EQY74_RS12340	COG2887	Belongs to the helicase family. UvrD subfamily
EQY74_RS12410	COG1793	dna ligase
EQY74_RS12455	COG4474	Belongs to the UPF0398 family
EQY74_RS12465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQY74_RS12495	COG0582	viral genome integration into host DNA
EQY74_RS12525	COG1404	Belongs to the peptidase S8 family
EQY74_RS12600	COG3655	Transcriptional regulator
EQY74_RS12665	COG1404	Belongs to the peptidase S8 family
EQY74_RS12695	COG0776	regulation of translation
EQY74_RS12725	COG4373	Mu-like prophage FluMu protein gp28
EQY74_RS12820	COG0582	viral genome integration into host DNA
EQY74_RS12830	COG0515	serine threonine protein kinase
EQY74_RS12830	COG0457	Tetratricopeptide repeat
EQY74_RS12910	COG0741	lytic transglycosylase activity
EQY74_RS12910	COG0739	heme binding
EQY74_RS12910	COG1196	nuclear chromosome segregation
EQY74_RS12920	COG2433	Pfam Transposase IS66
EQY74_RS12930	COG5434	Belongs to the glycosyl hydrolase 28 family
EQY74_RS12935	COG5632	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS12960	COG0457	Tetratricopeptide repeat
EQY74_RS13000	COG5444	nuclease activity
EQY74_RS13010	COG2002	toxin-antitoxin pair type II binding
EQY74_RS13020	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EQY74_RS13025	COG1509	lysine 2,3-aminomutase activity
EQY74_RS13030	COG0456	acetyltransferase
EQY74_RS13035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQY74_RS13040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EQY74_RS13045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EQY74_RS13050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EQY74_RS13065	COG0456	acetyltransferase
EQY74_RS13070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQY74_RS13075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EQY74_RS13080	COG1846	Transcriptional regulator
EQY74_RS13090	COG3706	GGDEF domain
EQY74_RS13095	COG0534	Mate efflux family protein
EQY74_RS13110	COG4698	Protein conserved in bacteria
EQY74_RS13115	COG2755	lipolytic protein G-D-S-L family
EQY74_RS13120	COG1999	signal sequence binding
EQY74_RS13135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EQY74_RS13140	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQY74_RS13145	COG1272	protein, Hemolysin III
EQY74_RS13150	COG0204	Acyl-transferase
EQY74_RS13155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EQY74_RS13160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQY74_RS13170	COG2521	methyltransferase
EQY74_RS13170	COG2136	Putative SAM-dependent methyltransferase
EQY74_RS13180	COG0129	dihydroxy-acid dehydratase activity
EQY74_RS13185	COG1413	lyase activity
EQY74_RS13190	COG1418	mRNA catabolic process
EQY74_RS13195	COG0386	Belongs to the glutathione peroxidase family
EQY74_RS13200	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EQY74_RS13205	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EQY74_RS13210	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQY74_RS13220	COG1278	Cold shock
EQY74_RS13240	COG0328	RNA-DNA hybrid ribonuclease activity
EQY74_RS13245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EQY74_RS13250	COG0328	RNA-DNA hybrid ribonuclease activity
EQY74_RS13260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQY74_RS13270	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQY74_RS13280	COG1755	Isoprenylcysteine carboxyl methyltransferase
EQY74_RS13285	COG3424	synthase
EQY74_RS13290	COG0456	acetyltransferase
EQY74_RS13295	COG2233	PERMEase
EQY74_RS13300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQY74_RS13305	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EQY74_RS13310	COG1199	ATP-dependent helicase activity
EQY74_RS13320	COG0116	Belongs to the methyltransferase superfamily
EQY74_RS13330	COG3599	regulation of cell shape
EQY74_RS13335	COG4474	Belongs to the UPF0398 family
EQY74_RS13345	COG3359	exonuclease
EQY74_RS13350	COG1205	dead DEAH box helicase
EQY74_RS13350	COG1111	helicase
EQY74_RS13355	COG2190	(PTS) system
EQY74_RS13360	COG0071	Belongs to the small heat shock protein (HSP20) family
EQY74_RS13395	COG3331	DNA recombination
EQY74_RS13400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQY74_RS13400	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQY74_RS13410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EQY74_RS13415	COG3935	DnaD domain protein
EQY74_RS13420	COG0017	Asparaginyl-tRNA synthetase
EQY74_RS13425	COG0436	Aminotransferase
EQY74_RS13430	COG5353	protein conserved in bacteria
EQY74_RS13440	COG1199	ATP-dependent helicase activity
EQY74_RS13440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EQY74_RS13445	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EQY74_RS13450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EQY74_RS13455	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EQY74_RS13470	COG0617	tRNA 3'-terminal CCA addition
EQY74_RS13475	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS13480	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EQY74_RS13485	COG1803	Methylglyoxal synthase
EQY74_RS13490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EQY74_RS13495	COG1694	Mazg nucleotide pyrophosphohydrolase
EQY74_RS13500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS13510	COG4347	Protein of unknown function (DUF1405)
EQY74_RS13515	COG2010	Cytochrome c
EQY74_RS13515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQY74_RS13520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EQY74_RS13525	COG0723	plastoquinol--plastocyanin reductase activity
EQY74_RS13535	COG5582	Belongs to the UPF0302 family
EQY74_RS13540	COG0457	Tetratricopeptide repeat
EQY74_RS13545	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EQY74_RS13550	COG0287	Prephenate dehydrogenase
EQY74_RS13555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EQY74_RS13560	COG0159	tryptophan synthase activity
EQY74_RS13565	COG0133	tryptophan synthase activity
EQY74_RS13570	COG0135	phosphoribosylanthranilate isomerase activity
EQY74_RS13575	COG0134	indole-3-glycerol-phosphate synthase activity
EQY74_RS13580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQY74_RS13585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EQY74_RS13590	COG4401	Chorismate mutase type I
EQY74_RS13595	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EQY74_RS13600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EQY74_RS13605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EQY74_RS13610	COG0105	UTP biosynthetic process
EQY74_RS13615	COG0142	geranyltranstransferase activity
EQY74_RS13620	COG2226	methyltransferase
EQY74_RS13625	COG0142	geranyltranstransferase activity
EQY74_RS13640	COG0776	regulation of translation
EQY74_RS13645	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EQY74_RS13665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EQY74_RS13670	COG1160	GTP binding
EQY74_RS13695	COG1304	FMN binding
EQY74_RS13700	COG0539	negative regulation of cytoplasmic translation
EQY74_RS13705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EQY74_RS13710	COG2959	enzyme of heme biosynthesis
EQY74_RS13715	COG3409	Peptidoglycan-binding domain 1 protein
EQY74_RS13715	COG3773	Cell wall hydrolase
EQY74_RS13720	COG2339	peptidase activity
EQY74_RS13730	COG0492	ferredoxin-NADP+ reductase activity
EQY74_RS13735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQY74_RS13740	COG4862	establishment of competence for transformation
EQY74_RS13745	COG1408	metallophosphoesterase
EQY74_RS13755	COG1388	LysM domain
EQY74_RS13760	COG1266	CAAX protease self-immunity
EQY74_RS13765	COG0514	ATP-dependent DNA helicase (RecQ)
EQY74_RS13770	COG4955	Helix-turn-helix domain
EQY74_RS13775	COG1141	Ferredoxin
EQY74_RS13780	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EQY74_RS13785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EQY74_RS13790	COG0739	heme binding
EQY74_RS13800	COG1595	DNA-templated transcription, initiation
EQY74_RS13805	COG1316	TRANSCRIPTIONal
EQY74_RS13820	COG5002	protein histidine kinase activity
EQY74_RS13825	COG0745	RESPONSE REGULATOR receiver
EQY74_RS13830	COG5002	protein histidine kinase activity
EQY74_RS13835	COG0745	RESPONSE REGULATOR receiver
EQY74_RS13840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQY74_RS13845	COG1333	cytochrome c biogenesis protein
EQY74_RS13850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS13855	COG1187	pseudouridine synthase activity
EQY74_RS13860	COG0700	Nucleoside recognition
EQY74_RS13865	COG2715	membrane protein required for spore maturation
EQY74_RS13870	COG1686	Belongs to the peptidase S11 family
EQY74_RS13880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EQY74_RS13885	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EQY74_RS13895	COG1547	Domain of unknown function (DUF309)
EQY74_RS13900	COG0456	acetyltransferase
EQY74_RS13905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EQY74_RS13910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQY74_RS13910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EQY74_RS13915	COG0307	riboflavin synthase, alpha
EQY74_RS13920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQY74_RS13920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EQY74_RS13945	COG0457	Tetratricopeptide repeat
EQY74_RS13950	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EQY74_RS13955	COG4086	secreted protein
EQY74_RS13960	COG4195	phage-related replication protein
EQY74_RS13965	COG0019	diaminopimelate decarboxylase activity
EQY74_RS13975	COG0697	spore germination
EQY74_RS13990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EQY74_RS14025	COG1686	Belongs to the peptidase S11 family
EQY74_RS14030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EQY74_RS14035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EQY74_RS14040	COG4974	Belongs to the 'phage' integrase family
EQY74_RS14050	COG0735	belongs to the Fur family
EQY74_RS14055	COG1300	Membrane
EQY74_RS14060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS14080	COG2153	protein acetylation
EQY74_RS14085	COG1379	DNA repair
EQY74_RS14090	COG0494	nUDIX hydrolase
EQY74_RS14100	COG1309	transcriptional regulator
EQY74_RS14110	COG0667	Aldo Keto reductase
EQY74_RS14120	COG1073	alpha beta
EQY74_RS14130	COG4918	Iron-sulphur cluster biosynthesis
EQY74_RS14140	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQY74_RS14140	COG0456	acetyltransferase
EQY74_RS14145	COG2329	Antibiotic biosynthesis monooxygenase
EQY74_RS14155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EQY74_RS14165	COG0747	negative chemotaxis
EQY74_RS14170	COG0601	transmembrane transport
EQY74_RS14175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS14180	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS14185	COG0534	Mate efflux family protein
EQY74_RS14200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQY74_RS14210	COG2211	Major facilitator Superfamily
EQY74_RS14215	COG0346	lactoylglutathione lyase activity
EQY74_RS14220	COG1072	(Pantothenic acid kinase))
EQY74_RS14235	COG1131	(ABC) transporter
EQY74_RS14255	COG4195	phage-related replication protein
EQY74_RS14270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS14275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQY74_RS14280	COG4187	Peptidase family M20/M25/M40
EQY74_RS14285	COG1902	pentaerythritol trinitrate reductase activity
EQY74_RS14290	COG0596	Alpha beta hydrolase
EQY74_RS14295	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQY74_RS14300	COG1234	tRNA 3'-trailer cleavage
EQY74_RS14305	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EQY74_RS14320	COG2358	TRAP transporter, solute receptor (TAXI family
EQY74_RS14325	COG2188	Transcriptional regulator
EQY74_RS14330	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS14335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS14340	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQY74_RS14345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS14350	COG1785	Belongs to the alkaline phosphatase family
EQY74_RS14355	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS14360	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EQY74_RS14365	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EQY74_RS14375	COG0706	membrane insertase activity
EQY74_RS14380	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQY74_RS14385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EQY74_RS14390	COG4129	membrane
EQY74_RS14395	COG1126	abc transporter atp-binding protein
EQY74_RS14400	COG0765	amino acid transport
EQY74_RS14405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EQY74_RS14415	COG1597	lipid kinase activity
EQY74_RS14420	COG0508	dehydrogenase complex catalyzes the overall conversion of
EQY74_RS14425	COG0022	dehydrogenase e1 component
EQY74_RS14430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EQY74_RS14435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EQY74_RS14440	COG3426	butyrate kinase activity
EQY74_RS14450	COG0280	phosphate acetyltransferase
EQY74_RS14455	COG3290	protein histidine kinase activity
EQY74_RS14455	COG3829	transcription factor binding
EQY74_RS14465	COG0584	glycerophosphoryl diester phosphodiesterase
EQY74_RS14470	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS14485	COG1045	serine acetyltransferase
EQY74_RS14495	COG0745	RESPONSE REGULATOR receiver
EQY74_RS14500	COG0750	zinc metalloprotease
EQY74_RS14505	COG0497	DNA recombination
EQY74_RS14510	COG1438	arginine binding
EQY74_RS14515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EQY74_RS14520	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EQY74_RS14525	COG0142	geranyltranstransferase activity
EQY74_RS14530	COG1722	exodeoxyribonuclease VII activity
EQY74_RS14535	COG1570	exodeoxyribonuclease VII activity
EQY74_RS14540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EQY74_RS14545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EQY74_RS14550	COG1302	Protein conserved in bacteria
EQY74_RS14555	COG0439	Biotin carboxylase
EQY74_RS14560	COG0511	ligase activity, forming carbon-carbon bonds
EQY74_RS14600	COG3854	ATPases associated with a variety of cellular activities
EQY74_RS14610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EQY74_RS14615	COG0006	proline dipeptidase activity
EQY74_RS14620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EQY74_RS14630	COG3872	metal-dependent enzyme
EQY74_RS14640	COG1752	Esterase of the alpha-beta hydrolase superfamily
EQY74_RS14645	COG1321	iron dependent repressor
EQY74_RS14650	COG0095	Lipoate-protein ligase
EQY74_RS14655	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQY74_RS14660	COG2113	Glycine betaine
EQY74_RS14665	COG4176	ABC-type proline glycine betaine transport system permease component
EQY74_RS14670	COG0517	IMP dehydrogenase activity
EQY74_RS14670	COG4175	Glycine betaine
EQY74_RS14675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQY74_RS14680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EQY74_RS14685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EQY74_RS14690	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQY74_RS14715	COG0681	Belongs to the peptidase S26 family
EQY74_RS14740	COG4940	Competence protein ComGF
EQY74_RS14750	COG4970	Tfp pilus assembly protein FimT
EQY74_RS14755	COG4537	Required for transformation and DNA binding
EQY74_RS14760	COG1459	type II secretion system
EQY74_RS14765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EQY74_RS14770	COG1366	Belongs to the anti-sigma-factor antagonist family
EQY74_RS14780	COG1393	Belongs to the ArsC family
EQY74_RS14790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS14800	COG0011	TIGRFAM Protein of
EQY74_RS14810	COG2866	Carboxypeptidase
EQY74_RS14815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS14820	COG1368	sulfuric ester hydrolase activity
EQY74_RS14825	COG1940	carbohydrate kinase activity
EQY74_RS14830	COG4483	Protein conserved in bacteria
EQY74_RS14835	COG0697	spore germination
EQY74_RS14840	COG0457	Tetratricopeptide repeat
EQY74_RS14840	COG0705	Rhomboid family
EQY74_RS14845	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EQY74_RS14850	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EQY74_RS14855	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS14870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQY74_RS14875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQY74_RS14880	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EQY74_RS14885	COG0581	inorganic phosphate transmembrane transporter activity
EQY74_RS14890	COG0573	inorganic phosphate transmembrane transporter activity
EQY74_RS14895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EQY74_RS14900	COG0768	penicillin binding
EQY74_RS14905	COG0477	Major facilitator Superfamily
EQY74_RS14910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EQY74_RS14915	COG2839	Protein conserved in bacteria
EQY74_RS14920	COG5521	maltodextrose utilization protein MalA
EQY74_RS14925	COG1388	LysM domain
EQY74_RS14930	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EQY74_RS14935	COG4709	membrane
EQY74_RS14940	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
EQY74_RS14945	COG0735	belongs to the Fur family
EQY74_RS14950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQY74_RS14955	COG1121	(ABC) transporter
EQY74_RS14960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS14970	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EQY74_RS14975	COG0513	Belongs to the DEAD box helicase family
EQY74_RS14985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EQY74_RS14990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EQY74_RS14995	COG2384	SAM-dependent methyltransferase
EQY74_RS15045	COG5444	nuclease activity
EQY74_RS15060	COG2010	Cytochrome c
EQY74_RS15065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EQY74_RS15070	COG0358	DNA primase activity
EQY74_RS15075	COG1671	Belongs to the UPF0178 family
EQY74_RS15080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EQY74_RS15085	COG0517	IMP dehydrogenase activity
EQY74_RS15090	COG0751	glycine-tRNA ligase activity
EQY74_RS15095	COG0752	glycyl-tRNA synthetase alpha subunit
EQY74_RS15100	COG1381	Involved in DNA repair and RecF pathway recombination
EQY74_RS15110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EQY74_RS15115	COG0295	cytidine deaminase activity
EQY74_RS15120	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EQY74_RS15125	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EQY74_RS15130	COG1480	7TM receptor with intracellular HD hydrolase
EQY74_RS15135	COG1702	phosphate starvation-inducible protein PhoH
EQY74_RS15140	COG0561	phosphatase activity
EQY74_RS15160	COG1030	water channel activity
EQY74_RS15165	COG1610	YqeY-like protein
EQY74_RS15170	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EQY74_RS15175	COG1283	sodium-dependent phosphate transmembrane transporter activity
EQY74_RS15180	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQY74_RS15185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EQY74_RS15190	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EQY74_RS15195	COG2264	protein methyltransferase activity
EQY74_RS15200	COG0484	heat shock protein binding
EQY74_RS15205	COG0443	Heat shock 70 kDa protein
EQY74_RS15210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EQY74_RS15215	COG1420	regulation of RNA biosynthetic process
EQY74_RS15220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EQY74_RS15225	COG0481	GTPase activity
EQY74_RS15235	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS15240	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EQY74_RS15245	COG0268	Binds directly to 16S ribosomal RNA
EQY74_RS15250	COG1466	dna polymerase III delta subunit
EQY74_RS15260	COG0658	competence protein
EQY74_RS15260	COG2333	competence protein COMEC
EQY74_RS15265	COG2131	deaminase
EQY74_RS15270	COG1596	polysaccharide export
EQY74_RS15270	COG1555	photosystem II stabilization
EQY74_RS15275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EQY74_RS15280	COG2226	methyltransferase
EQY74_RS15285	COG0799	negative regulation of ribosome biogenesis
EQY74_RS15290	COG1713	HD superfamily hydrolase involved in NAD metabolism
EQY74_RS15295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EQY74_RS15300	COG1534	Rna-binding protein
EQY74_RS15305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EQY74_RS15310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EQY74_RS15315	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EQY74_RS15325	COG2755	lipolytic protein G-D-S-L family
EQY74_RS15330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EQY74_RS15335	COG5609	conserved protein (DUF2294)
EQY74_RS15340	COG3383	formate dehydrogenase (NAD+) activity
EQY74_RS15345	COG2427	Protein of unknown function (DUF1641)
EQY74_RS15375	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS15430	COG0425	Belongs to the sulfur carrier protein TusA family
EQY74_RS15430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQY74_RS15440	COG2197	response regulator
EQY74_RS15445	COG4585	Histidine kinase
EQY74_RS15450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS15455	COG0730	response to heat
EQY74_RS15460	COG0425	Belongs to the sulfur carrier protein TusA family
EQY74_RS15465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS15465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQY74_RS15470	COG0425	Belongs to the sulfur carrier protein TusA family
EQY74_RS15470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQY74_RS15475	COG2210	Belongs to the sulfur carrier protein TusA family
EQY74_RS15480	COG1937	Protein conserved in bacteria
EQY74_RS15525	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQY74_RS15530	COG0113	porphobilinogen synthase activity
EQY74_RS15535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EQY74_RS15540	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
EQY74_RS15545	COG1733	regulation of RNA biosynthetic process
EQY74_RS15550	COG3239	Fatty acid desaturase
EQY74_RS15555	COG4585	Histidine kinase
EQY74_RS15560	COG2197	response regulator
EQY74_RS15565	COG0492	ferredoxin-NADP+ reductase activity
EQY74_RS15570	COG0747	negative chemotaxis
EQY74_RS15575	COG0601	transmembrane transport
EQY74_RS15580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EQY74_RS15585	COG0444	Belongs to the ABC transporter superfamily
EQY74_RS15590	COG4608	Belongs to the ABC transporter superfamily
EQY74_RS15610	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS15625	COG2124	cytochrome p450
EQY74_RS15630	COG0730	response to heat
EQY74_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS15650	COG1621	beta-fructofuranosidase activity
EQY74_RS15655	COG3716	PTS system mannose fructose sorbose family IID component
EQY74_RS15660	COG3715	PTS system
EQY74_RS15665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS15670	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS15675	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EQY74_RS15675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EQY74_RS15695	COG2169	Transcriptional regulator
EQY74_RS15700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EQY74_RS15705	COG0656	L-ascorbic acid biosynthetic process
EQY74_RS15710	COG2814	Major facilitator Superfamily
EQY74_RS15715	COG1733	regulation of RNA biosynthetic process
EQY74_RS15720	COG3340	Belongs to the peptidase S51 family
EQY74_RS15725	COG1587	Uroporphyrinogen-III synthase
EQY74_RS15735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS15740	COG0583	DNA-binding transcription factor activity
EQY74_RS15745	COG2814	Major facilitator Superfamily
EQY74_RS15755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EQY74_RS15755	COG2124	cytochrome p450
EQY74_RS15760	COG1309	transcriptional regulator
EQY74_RS15765	COG1404	Belongs to the peptidase S8 family
EQY74_RS15770	COG2226	methyltransferase
EQY74_RS15795	COG0626	cystathionine gamma-synthase activity
EQY74_RS15800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQY74_RS15805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EQY74_RS15810	COG2226	methyltransferase
EQY74_RS15825	COG0768	penicillin binding
EQY74_RS15830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EQY74_RS15835	COG0572	uridine kinase
EQY74_RS15840	COG0826	peptidase U32
EQY74_RS15845	COG0826	peptidase U32
EQY74_RS15850	COG4122	O-methyltransferase activity
EQY74_RS15855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EQY74_RS15860	COG3906	Belongs to the UPF0473 family
EQY74_RS15870	COG4472	Bacterial protein of unknown function (DUF965)
EQY74_RS15875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EQY74_RS15880	COG0628	permease
EQY74_RS15895	COG3881	PFAM PRC-barrel domain
EQY74_RS15900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EQY74_RS15905	COG0457	Tetratricopeptide repeat
EQY74_RS15910	COG0482	sulfurtransferase activity
EQY74_RS15915	COG1104	cysteine desulfurase activity
EQY74_RS15920	COG1959	2 iron, 2 sulfur cluster binding
EQY74_RS15925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EQY74_RS15930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EQY74_RS15940	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EQY74_RS15945	COG0124	histidyl-tRNA synthetase
EQY74_RS15950	COG4991	sh3 domain protein
EQY74_RS15950	COG3103	Sh3 type 3 domain protein
EQY74_RS15950	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS15955	COG1490	D-aminoacyl-tRNA deacylase activity
EQY74_RS15960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EQY74_RS15965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EQY74_RS15970	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EQY74_RS15970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EQY74_RS15975	COG5416	Lipopolysaccharide assembly protein A domain
EQY74_RS15980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQY74_RS15980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EQY74_RS15990	COG2244	polysaccharide biosynthetic process
EQY74_RS15995	COG2323	membrane
EQY74_RS16005	COG1862	Preprotein translocase
EQY74_RS16010	COG0343	queuine tRNA-ribosyltransferase activity
EQY74_RS16015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EQY74_RS16025	COG2255	four-way junction helicase activity
EQY74_RS16030	COG0632	four-way junction helicase activity
EQY74_RS16040	COG2112	serine threonine protein kinase
EQY74_RS16050	COG2318	DinB family
EQY74_RS16055	COG4195	phage-related replication protein
EQY74_RS16070	COG0217	transcriptional regulatory protein
EQY74_RS16080	COG1388	LysM domain
EQY74_RS16085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EQY74_RS16090	COG0157	Belongs to the NadC ModD family
EQY74_RS16095	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EQY74_RS16100	COG1104	cysteine desulfurase activity
EQY74_RS16105	COG1827	regulation of RNA biosynthetic process
EQY74_RS16110	COG0077	Prephenate dehydratase
EQY74_RS16115	COG4492	Belongs to the UPF0735 family
EQY74_RS16120	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EQY74_RS16125	COG3290	protein histidine kinase activity
EQY74_RS16130	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EQY74_RS16135	COG2868	ribosomal protein
EQY74_RS16140	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EQY74_RS16145	COG1994	Peptidase M50
EQY74_RS16150	COG0739	heme binding
EQY74_RS16155	COG3832	glyoxalase III activity
EQY74_RS16160	COG0640	Transcriptional regulator
EQY74_RS16165	COG2894	cell division
EQY74_RS16170	COG0850	regulation of cytokinetic process
EQY74_RS16175	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EQY74_RS16185	COG1077	Cell shape determining protein MreB Mrl
EQY74_RS16190	COG2003	Belongs to the UPF0758 family
EQY74_RS16195	COG0424	maF-like protein
EQY74_RS16205	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EQY74_RS16210	COG0285	dihydrofolate synthase activity
EQY74_RS16215	COG0525	valine-tRNA ligase activity
EQY74_RS16225	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQY74_RS16230	COG1388	LysM domain
EQY74_RS16235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EQY74_RS16240	COG0113	porphobilinogen synthase activity
EQY74_RS16245	COG1587	Uroporphyrinogen-III synthase
EQY74_RS16250	COG0181	hydroxymethylbilane synthase activity
EQY74_RS16255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EQY74_RS16260	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EQY74_RS16270	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EQY74_RS16275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EQY74_RS16280	COG0470	DNA polymerase III
EQY74_RS16280	COG1067	ATP-dependent peptidase activity
EQY74_RS16285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EQY74_RS16290	COG0544	peptidyl-prolyl cis-trans isomerase activity
EQY74_RS16295	COG0457	Tetratricopeptide repeat
EQY74_RS16295	COG1477	protein flavinylation
EQY74_RS16300	COG0066	3-isopropylmalate dehydratase activity
EQY74_RS16305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EQY74_RS16310	COG0473	3-isopropylmalate dehydrogenase activity
EQY74_RS16315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EQY74_RS16320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EQY74_RS16325	COG0440	acetolactate synthase activity
EQY74_RS16330	COG0028	Belongs to the TPP enzyme family
EQY74_RS16335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQY74_RS16345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EQY74_RS16365	COG5518	Phage portal protein
EQY74_RS16370	COG1783	phage Terminase large subunit
EQY74_RS16410	COG5444	nuclease activity
EQY74_RS16415	COG0457	Tetratricopeptide repeat
EQY74_RS16435	COG0622	Phosphoesterase
EQY74_RS16440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EQY74_RS16445	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EQY74_RS16450	COG5401	PFAM Sporulation and spore germination
EQY74_RS16455	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EQY74_RS16460	COG1846	Transcriptional regulator
EQY74_RS16465	COG2197	response regulator
EQY74_RS16470	COG4221	oxidoreductase activity
EQY74_RS16475	COG0824	Thioesterase
EQY74_RS16480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EQY74_RS16485	COG1053	succinate dehydrogenase
EQY74_RS16490	COG2009	succinate dehydrogenase
EQY74_RS16495	COG1719	4-vinyl reductase, 4VR
EQY74_RS16500	COG0527	aspartate kinase activity
EQY74_RS16510	COG0322	excinuclease ABC activity
EQY74_RS16515	COG3118	belongs to the thioredoxin family
EQY74_RS16520	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EQY74_RS16525	COG2086	electron transfer activity
EQY74_RS16530	COG1024	Enoyl-CoA hydratase
EQY74_RS16535	COG1309	transcriptional regulator
EQY74_RS16540	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS16545	COG3766	membrane
EQY74_RS16550	COG1193	negative regulation of DNA recombination
EQY74_RS16555	COG1796	DNA polymerase
EQY74_RS16555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQY74_RS16560	COG1286	toxin biosynthetic process
EQY74_RS16565	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EQY74_RS16570	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EQY74_RS16600	COG1137	ATPase activity
EQY74_RS16615	COG0072	phenylalanine-tRNA ligase activity
EQY74_RS16615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQY74_RS16620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EQY74_RS16625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EQY74_RS16635	COG1966	Carbon starvation protein
EQY74_RS16650	COG0395	ABC-type sugar transport system, permease component
EQY74_RS16655	COG1175	transmembrane transport
EQY74_RS16660	COG1653	transport
EQY74_RS16665	COG0371	Dehydrogenase
EQY74_RS16670	COG0235	Class ii aldolase
EQY74_RS16675	COG1069	ribulokinase activity
EQY74_RS16685	COG3507	Belongs to the glycosyl hydrolase 43 family
EQY74_RS16690	COG1363	Peptidase, m42
EQY74_RS16700	COG3326	Membrane
EQY74_RS16705	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EQY74_RS16710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EQY74_RS16715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EQY74_RS16720	COG1346	cytolysis
EQY74_RS16730	COG3540	Alkaline phosphatase
EQY74_RS16735	COG3279	Response regulator of the LytR AlgR family
EQY74_RS16740	COG3275	phosphorelay sensor kinase activity
EQY74_RS16750	COG1011	Hydrolase
EQY74_RS16755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EQY74_RS16765	COG0398	Pfam SNARE associated Golgi protein
EQY74_RS16770	COG1484	DNA-dependent DNA replication
EQY74_RS16775	COG3611	Membrane attachment protein
EQY74_RS16780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EQY74_RS16795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EQY74_RS16800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQY74_RS16805	COG3866	Pectate lyase
EQY74_RS16810	COG0237	dephospho-CoA kinase activity
EQY74_RS16815	COG1971	Probably functions as a manganese efflux pump
EQY74_RS16820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EQY74_RS16825	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQY74_RS16825	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EQY74_RS16830	COG5002	protein histidine kinase activity
EQY74_RS16835	COG0745	RESPONSE REGULATOR receiver
EQY74_RS16840	COG0039	L-malate dehydrogenase activity
EQY74_RS16845	COG0538	isocitrate dehydrogenase activity
EQY74_RS16850	COG0372	Belongs to the citrate synthase family
EQY74_RS16855	COG2707	UPF0756 membrane protein
EQY74_RS16860	COG0628	permease
EQY74_RS16865	COG3030	protein affecting phage T7 exclusion by the F plasmid
EQY74_RS16875	COG0205	6-phosphofructokinase activity
EQY74_RS16880	COG0825	malonyl-CoA metabolic process
EQY74_RS16885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EQY74_RS16890	COG0281	malic enzyme
EQY74_RS16895	COG0587	DNA-directed DNA polymerase activity
EQY74_RS16915	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EQY74_RS16925	COG4109	DRTGG domain
EQY74_RS16930	COG1695	Transcriptional regulator
EQY74_RS16935	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EQY74_RS16940	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS16945	COG0165	Argininosuccinate lyase
EQY74_RS16950	COG0137	argininosuccinate synthase activity
EQY74_RS16955	COG0521	Mo-molybdopterin cofactor biosynthetic process
EQY74_RS16960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EQY74_RS16965	COG0827	DNA restriction-modification system
EQY74_RS16970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EQY74_RS16975	COG3874	Sporulation protein YtfJ
EQY74_RS16985	COG1714	RDD family
EQY74_RS16990	COG0616	signal peptide processing
EQY74_RS16995	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EQY74_RS17000	COG1566	PFAM secretion protein HlyD family protein
EQY74_RS17015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQY74_RS17025	COG0301	tRNA thio-modification
EQY74_RS17030	COG1104	cysteine desulfurase activity
EQY74_RS17035	COG1114	Component of the transport system for branched-chain amino acids
EQY74_RS17040	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EQY74_RS17045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EQY74_RS17050	COG1309	transcriptional regulator
EQY74_RS17055	COG1956	GAF domain-containing protein
EQY74_RS17065	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EQY74_RS17080	COG3152	Membrane
EQY74_RS17090	COG1522	sequence-specific DNA binding
EQY74_RS17095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EQY74_RS17100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EQY74_RS17105	COG0454	-acetyltransferase
EQY74_RS17110	COG0517	IMP dehydrogenase activity
EQY74_RS17115	COG0123	including yeast histone deacetylase and acetoin utilization protein
EQY74_RS17120	COG1360	Flagellar Motor Protein
EQY74_RS17125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EQY74_RS17130	COG1609	Transcriptional regulator
EQY74_RS17135	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EQY74_RS17135	COG1605	Chorismate mutase
EQY74_RS17145	COG3118	belongs to the thioredoxin family
EQY74_RS17150	COG4980	gas vesicle protein
EQY74_RS17155	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EQY74_RS17160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EQY74_RS17165	COG1674	ftsk spoiiie
EQY74_RS17170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EQY74_RS17175	COG4848	Belongs to the UPF0354 family
EQY74_RS17180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS17190	COG1363	Peptidase, m42
EQY74_RS17195	COG5584	Small secreted protein
EQY74_RS17200	COG0281	malic enzyme
EQY74_RS17205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EQY74_RS17210	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EQY74_RS17220	COG0510	thiamine kinase activity
EQY74_RS17230	COG1597	lipid kinase activity
EQY74_RS17240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EQY74_RS17245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EQY74_RS17260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQY74_RS17265	COG2252	PERMEase
EQY74_RS17270	COG1349	DNA-binding transcription factor activity
EQY74_RS17275	COG1187	pseudouridine synthase activity
EQY74_RS17280	COG2244	polysaccharide biosynthetic process
EQY74_RS17285	COG2081	HI0933 family
EQY74_RS17290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EQY74_RS17300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EQY74_RS17305	COG0457	Tetratricopeptide repeat
EQY74_RS17315	COG5578	integral membrane protein
EQY74_RS17320	COG0673	inositol 2-dehydrogenase activity
EQY74_RS17325	COG1653	transport
EQY74_RS17330	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EQY74_RS17335	COG4209	transmembrane transport
EQY74_RS17340	COG2207	Transcriptional regulator
EQY74_RS17345	COG1653	transport
EQY74_RS17350	COG0395	ABC-type sugar transport system, permease component
EQY74_RS17355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQY74_RS17360	COG1073	alpha beta
EQY74_RS17370	COG0583	DNA-binding transcription factor activity
EQY74_RS17375	COG0346	lactoylglutathione lyase activity
EQY74_RS17380	COG0495	leucyl-tRNA aminoacylation
EQY74_RS17390	COG2814	Major facilitator Superfamily
EQY74_RS17400	COG2433	Pfam Transposase IS66
EQY74_RS17405	COG0577	efflux transmembrane transporter activity
EQY74_RS17410	COG1136	(ABC) transporter
EQY74_RS17420	COG1131	(ABC) transporter
EQY74_RS17425	COG1725	Transcriptional regulator
EQY74_RS17435	COG1242	4 iron, 4 sulfur cluster binding
EQY74_RS17440	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EQY74_RS17445	COG1301	dicarboxylic acid transport
EQY74_RS17455	COG2267	carboxylic ester hydrolase activity
EQY74_RS17460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EQY74_RS17465	COG0671	phosphoesterase, PA-phosphatase related
EQY74_RS17470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQY74_RS17470	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS17475	COG0367	asparagine synthase
EQY74_RS17480	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EQY74_RS17485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EQY74_RS17490	COG1301	dicarboxylic acid transport
EQY74_RS17500	COG1506	peptidase
EQY74_RS17505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EQY74_RS17510	COG1116	anion transmembrane transporter activity
EQY74_RS17515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EQY74_RS17520	COG0494	nUDIX hydrolase
EQY74_RS17530	COG4824	toxin secretion phage lysis holin
EQY74_RS17535	COG0783	Belongs to the Dps family
EQY74_RS17550	COG1854	S-ribosylhomocysteine lyase activity
EQY74_RS17555	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EQY74_RS17560	COG0288	reversible hydration of carbon dioxide
EQY74_RS17565	COG0523	cobalamin synthesis protein
EQY74_RS17570	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQY74_RS17575	COG0254	rRNA binding
EQY74_RS17580	COG1271	oxidase subunit
EQY74_RS17585	COG1294	oxidase, subunit
EQY74_RS17600	COG4948	Mandelate Racemase Muconate Lactonizing
EQY74_RS17605	COG0318	PFAM AMP-dependent synthetase and ligase
EQY74_RS17610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EQY74_RS17615	COG0596	Alpha beta hydrolase
EQY74_RS17620	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EQY74_RS17625	COG1169	isochorismate synthase
EQY74_RS17630	COG1575	Belongs to the MenA family. Type 1 subfamily
EQY74_RS17635	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EQY74_RS17640	COG0058	SHG alpha-glucan phosphorylase activity
EQY74_RS17645	COG0297	glycogen (starch) synthase activity
EQY74_RS17650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EQY74_RS17655	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EQY74_RS17660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EQY74_RS17785	COG1609	Transcriptional regulator
EQY74_RS17790	COG3859	Proton-coupled thiamine transporter YuaJ
EQY74_RS17795	COG3764	Sortase (surface protein transpeptidase)
EQY74_RS17810	COG0457	Tetratricopeptide repeat
EQY74_RS17815	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EQY74_RS17820	COG0569	domain protein
EQY74_RS17825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQY74_RS17835	COG2318	DinB family
EQY74_RS17845	COG1454	alcohol dehydrogenase
EQY74_RS17850	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS17855	COG1510	regulation of RNA biosynthetic process
EQY74_RS17865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EQY74_RS17870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EQY74_RS17875	COG2140	Oxalate decarboxylase
EQY74_RS17930	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
EQY74_RS17940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EQY74_RS17945	COG0726	polysaccharide deacetylase
EQY74_RS17950	COG1408	metallophosphoesterase
EQY74_RS17955	COG1968	undecaprenyl-diphosphatase activity
EQY74_RS17960	COG0628	permease
EQY74_RS17965	COG0673	inositol 2-dehydrogenase activity
EQY74_RS17970	COG0693	protein deglycase activity
EQY74_RS17975	COG0840	transmembrane signaling receptor activity
EQY74_RS17980	COG0840	transmembrane signaling receptor activity
EQY74_RS17985	COG0840	transmembrane signaling receptor activity
EQY74_RS17995	COG2070	2-Nitropropane dioxygenase
EQY74_RS18000	COG0432	Pfam Uncharacterised protein family UPF0047
EQY74_RS18005	COG0366	Alpha amylase catalytic
EQY74_RS18020	COG5297	Belongs to the glycosyl hydrolase family 6
EQY74_RS18025	COG1253	flavin adenine dinucleotide binding
EQY74_RS18030	COG2738	Putative neutral zinc metallopeptidase
EQY74_RS18055	COG2323	membrane
EQY74_RS18060	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EQY74_RS18070	COG0166	Belongs to the GPI family
EQY74_RS18075	COG1979	alcohol dehydrogenase
EQY74_RS18080	COG2155	Conserved Protein
EQY74_RS18085	COG1098	S1 RNA binding domain
EQY74_RS18090	COG0436	Aminotransferase
EQY74_RS18095	COG1522	sequence-specific DNA binding
EQY74_RS18100	COG2267	carboxylic ester hydrolase activity
EQY74_RS18115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EQY74_RS18130	COG5018	Exonuclease
EQY74_RS18135	COG2814	Major facilitator Superfamily
EQY74_RS18140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQY74_RS18145	COG3011	Protein conserved in bacteria
EQY74_RS18155	COG3290	protein histidine kinase activity
EQY74_RS18160	COG4565	transcriptional regulatory protein
EQY74_RS18170	COG1183	phosphatidylcholine synthase activity
EQY74_RS18175	COG0586	Pfam SNARE associated Golgi protein
EQY74_RS18180	COG0688	phosphatidylethanolamine metabolic process
EQY74_RS18185	COG3493	citrate carrier protein
EQY74_RS18195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EQY74_RS18195	COG2111	Na H antiporter
EQY74_RS18200	COG2111	Na H antiporter
EQY74_RS18205	COG1006	Multisubunit Na H antiporter MnhC subunit
EQY74_RS18210	COG0651	ATP synthesis coupled electron transport
EQY74_RS18215	COG1863	multisubunit Na H antiporter MnhE subunit
EQY74_RS18220	COG2212	antiporter activity
EQY74_RS18225	COG1320	monovalent cation:proton antiporter activity
EQY74_RS18230	COG2050	protein possibly involved in aromatic compounds catabolism
EQY74_RS18235	COG2197	response regulator
EQY74_RS18240	COG4585	Histidine kinase
EQY74_RS18270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EQY74_RS18275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EQY74_RS18280	COG1335	isochorismatase
EQY74_RS18285	COG5506	Protein of unknown function (DUF1694)
EQY74_RS18300	COG0628	permease
EQY74_RS18305	COG1959	2 iron, 2 sulfur cluster binding
EQY74_RS18310	COG0657	acetylesterase activity
EQY74_RS18320	COG1418	mRNA catabolic process
EQY74_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS18335	COG1511	domain protein
EQY74_RS18340	COG0433	COG0433 Predicted ATPase
EQY74_RS18340	COG1674	ftsk spoiiie
EQY74_RS18345	COG4499	WXG100 protein secretion system (Wss), protein YukC
EQY74_RS18350	COG5417	Belongs to the EsaB family
EQY74_RS18355	COG4842	Belongs to the WXG100 family
EQY74_RS18360	COG1115	amino acid carrier protein
EQY74_RS18365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EQY74_RS18365	COG2508	Transcriptional regulator
EQY74_RS18370	COG0686	Belongs to the AlaDH PNT family
EQY74_RS18380	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EQY74_RS18385	COG1268	BioY protein
EQY74_RS18390	COG2056	Na+-H+ antiporter family
EQY74_RS18395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EQY74_RS18400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EQY74_RS18405	COG3584	3D domain protein
EQY74_RS18415	COG1252	NADH dehydrogenase
EQY74_RS18420	COG0492	ferredoxin-NADP+ reductase activity
EQY74_RS18435	COG0456	acetyltransferase
EQY74_RS18440	COG0316	Belongs to the HesB IscA family
EQY74_RS18445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EQY74_RS18450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQY74_RS18455	COG4844	belongs to the
EQY74_RS18460	COG1252	NADH dehydrogenase
EQY74_RS18465	COG5646	InterPro IPR014922
EQY74_RS18475	COG0457	Tetratricopeptide repeat
EQY74_RS18480	COG3479	Phenolic acid decarboxylase
EQY74_RS18490	COG4837	Protein of unknown function (DUF1462)
EQY74_RS18495	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EQY74_RS18500	COG1506	peptidase
EQY74_RS18500	COG4946	Tricorn protease homolog
EQY74_RS18500	COG0823	Involved in the tonB-independent uptake of proteins
EQY74_RS18505	COG0083	homoserine kinase activity
EQY74_RS18510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EQY74_RS18515	COG0460	homoserine dehydrogenase
EQY74_RS18525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EQY74_RS18530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EQY74_RS18535	COG0647	UMP catabolic process
EQY74_RS18540	COG2445	Protein of unknown function DUF86
EQY74_RS18545	COG4470	Protein conserved in bacteria
EQY74_RS18560	COG0739	heme binding
EQY74_RS18570	COG0733	neurotransmitter:sodium symporter activity
EQY74_RS18580	COG3377	Domain of unknown function (DUF1805)
EQY74_RS18585	COG0737	Belongs to the 5'-nucleotidase family
EQY74_RS18590	COG0730	response to heat
EQY74_RS18595	COG1801	Protein of unknown function DUF72
EQY74_RS18605	COG3226	Transcriptional regulator
EQY74_RS18615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EQY74_RS18620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EQY74_RS18625	COG2508	Transcriptional regulator
EQY74_RS18630	COG2814	Major facilitator Superfamily
EQY74_RS18635	COG1288	antiporter activity
EQY74_RS18640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQY74_RS18645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EQY74_RS18650	COG2356	endonuclease I
EQY74_RS18660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EQY74_RS18675	COG0457	Tetratricopeptide repeat
EQY74_RS18680	COG0719	Fe-S assembly protein
EQY74_RS18685	COG0822	iron-sulfur transferase activity
EQY74_RS18690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQY74_RS18695	COG0719	Fe-S assembly protein
EQY74_RS18700	COG0396	ATPase activity
EQY74_RS18710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQY74_RS18715	COG1464	Belongs to the NlpA lipoprotein family
EQY74_RS18720	COG2011	ABC-type metal ion transport system permease component
EQY74_RS18725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EQY74_RS18735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EQY74_RS18740	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EQY74_RS18750	COG0509	glycine decarboxylation via glycine cleavage system
EQY74_RS18755	COG1393	Belongs to the ArsC family
EQY74_RS18760	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS18765	COG0183	Belongs to the thiolase family
EQY74_RS18785	COG5577	PFAM Coat F domain
EQY74_RS18800	COG1120	ATPase activity
EQY74_RS18805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS18815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS18840	COG0783	Belongs to the Dps family
EQY74_RS18845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQY74_RS18850	COG0745	RESPONSE REGULATOR receiver
EQY74_RS18855	COG2770	Histidine kinase
EQY74_RS18855	COG2205	protein histidine kinase activity
EQY74_RS18860	COG1309	transcriptional regulator
EQY74_RS18865	COG0114	fumarate hydratase activity
EQY74_RS18875	COG0697	spore germination
EQY74_RS18880	COG0814	amino acid
EQY74_RS18895	COG2197	response regulator
EQY74_RS18900	COG4585	Histidine kinase
EQY74_RS18905	COG4758	membrane
EQY74_RS18915	COG1842	Phage shock protein A
EQY74_RS18920	COG4758	membrane
EQY74_RS18925	COG4677	pectinesterase activity
EQY74_RS18930	COG2096	Adenosyltransferase
EQY74_RS18935	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS18945	COG1454	alcohol dehydrogenase
EQY74_RS18950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQY74_RS18960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS18965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS18970	COG1802	Transcriptional regulator
EQY74_RS18975	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS18980	COG2258	MOSC domain
EQY74_RS18985	COG0583	DNA-binding transcription factor activity
EQY74_RS18995	COG2721	sulfolactate sulfo-lyase activity
EQY74_RS19005	COG1609	Transcriptional regulator
EQY74_RS19010	COG2211	Major facilitator Superfamily
EQY74_RS19015	COG1904	glucuronate isomerase
EQY74_RS19020	COG2205	protein histidine kinase activity
EQY74_RS19025	COG0745	RESPONSE REGULATOR receiver
EQY74_RS19030	COG1120	ATPase activity
EQY74_RS19035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS19040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS19045	COG0531	amino acid
EQY74_RS19055	COG1988	membrane-bound metal-dependent
EQY74_RS19060	COG1368	sulfuric ester hydrolase activity
EQY74_RS19065	COG2814	Major facilitator Superfamily
EQY74_RS19070	COG0656	L-ascorbic acid biosynthetic process
EQY74_RS19075	COG1940	carbohydrate kinase activity
EQY74_RS19080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EQY74_RS19090	COG3973	AAA domain
EQY74_RS19095	COG2860	membrane
EQY74_RS19100	COG0456	acetyltransferase
EQY74_RS19100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EQY74_RS19105	COG0456	acetyltransferase
EQY74_RS19110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EQY74_RS19115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EQY74_RS19120	COG2217	Heavy metal translocating P-type atpase
EQY74_RS19125	COG1653	transport
EQY74_RS19130	COG1175	transmembrane transport
EQY74_RS19135	COG0395	ABC-type sugar transport system, permease component
EQY74_RS19140	COG1501	Belongs to the glycosyl hydrolase 31 family
EQY74_RS19145	COG1472	Belongs to the glycosyl hydrolase 3 family
EQY74_RS19150	COG1121	(ABC) transporter
EQY74_RS19155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EQY74_RS19160	COG0803	Belongs to the bacterial solute-binding protein 9 family
EQY74_RS19175	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQY74_RS19175	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EQY74_RS19180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS19180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS19180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EQY74_RS19195	COG2217	Heavy metal translocating P-type atpase
EQY74_RS19200	COG2608	mercury ion transmembrane transporter activity
EQY74_RS19205	COG1937	Protein conserved in bacteria
EQY74_RS19210	COG0693	protein deglycase activity
EQY74_RS19215	COG1349	DNA-binding transcription factor activity
EQY74_RS19220	COG1070	Carbohydrate kinase
EQY74_RS19225	COG4952	isomerase
EQY74_RS19235	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS19235	COG3347	Dehydrogenase
EQY74_RS19240	COG2814	Major facilitator Superfamily
EQY74_RS19245	COG2814	Major facilitator Superfamily
EQY74_RS19255	COG2124	cytochrome p450
EQY74_RS19265	COG1846	Transcriptional regulator
EQY74_RS19275	COG0673	inositol 2-dehydrogenase activity
EQY74_RS19280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EQY74_RS19285	COG1054	Belongs to the UPF0176 family
EQY74_RS19295	COG1191	sigma factor activity
EQY74_RS19305	COG2140	Oxalate decarboxylase
EQY74_RS19375	COG5444	nuclease activity
EQY74_RS19420	COG1705	Flagellar rod assembly protein muramidase FlgJ
EQY74_RS19430	COG5280	Phage tail tape measure protein TP901
EQY74_RS19430	COG3953	SLT domain
EQY74_RS19490	COG4626	Terminase
EQY74_RS19490	COG1802	Transcriptional regulator
EQY74_RS19665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EQY74_RS19670	COG0557	exoribonuclease II activity
EQY74_RS19675	COG1647	Serine aminopeptidase, S33
EQY74_RS19680	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EQY74_RS19685	COG2002	toxin-antitoxin pair type II binding
EQY74_RS19690	COG1476	TRANSCRIPTIONal
EQY74_RS19695	COG1396	sequence-specific DNA binding
EQY74_RS19700	COG1396	sequence-specific DNA binding
EQY74_RS19705	COG1174	glycine betaine transport
EQY74_RS19710	COG1732	Glycine betaine
EQY74_RS19715	COG1174	glycine betaine transport
EQY74_RS19720	COG1125	glycine betaine transport
EQY74_RS19720	COG0517	IMP dehydrogenase activity
EQY74_RS19725	COG1510	regulation of RNA biosynthetic process
EQY74_RS19730	COG2095	MarC family integral membrane protein
EQY74_RS19735	COG3064	Membrane
EQY74_RS19745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS19760	COG0693	protein deglycase activity
EQY74_RS19765	COG0148	phosphopyruvate hydratase activity
EQY74_RS19770	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EQY74_RS19775	COG0149	triose-phosphate isomerase activity
EQY74_RS19780	COG0126	phosphoglycerate kinase activity
EQY74_RS19790	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EQY74_RS19795	COG2390	Transcriptional regulator
EQY74_RS19800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQY74_RS19805	COG1113	amino acid transport
EQY74_RS19825	COG1556	Lactate utilization protein
EQY74_RS19830	COG1139	Iron-sulfur cluster binding protein
EQY74_RS19835	COG0247	lactate metabolic process
EQY74_RS19840	COG2186	Transcriptional regulator
EQY74_RS19845	COG1620	l-lactate permease
EQY74_RS19850	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EQY74_RS19860	COG5039	Polysaccharide pyruvyl transferase
EQY74_RS19865	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQY74_RS19870	COG0110	maltose O-acetyltransferase activity
EQY74_RS19875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EQY74_RS19880	COG2244	polysaccharide biosynthetic process
EQY74_RS19885	COG1216	Glycosyl transferase, family 2
EQY74_RS19890	COG5039	Polysaccharide pyruvyl transferase
EQY74_RS19895	COG1216	Glycosyl transferase, family 2
EQY74_RS19905	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS19910	COG1215	transferase activity, transferring glycosyl groups
EQY74_RS19915	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS19920	COG1086	Polysaccharide biosynthesis protein
EQY74_RS19925	COG0489	protein tyrosine kinase activity
EQY74_RS19930	COG3944	biosynthesis protein
EQY74_RS19935	COG1396	sequence-specific DNA binding
EQY74_RS19940	COG2249	NAD(P)H dehydrogenase (quinone) activity
EQY74_RS19950	COG2271	Major facilitator Superfamily
EQY74_RS19960	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EQY74_RS19975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EQY74_RS19985	COG1733	regulation of RNA biosynthetic process
EQY74_RS19990	COG1902	pentaerythritol trinitrate reductase activity
EQY74_RS19995	COG1621	beta-fructofuranosidase activity
EQY74_RS20000	COG1621	beta-fructofuranosidase activity
EQY74_RS20015	COG0740	serine-type endopeptidase activity
EQY74_RS20020	COG1611	Belongs to the LOG family
EQY74_RS20025	COG1694	Mazg nucleotide pyrophosphohydrolase
EQY74_RS20035	COG0659	secondary active sulfate transmembrane transporter activity
EQY74_RS20040	COG0288	reversible hydration of carbon dioxide
EQY74_RS20045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQY74_RS20050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EQY74_RS20055	COG0640	Transcriptional regulator
EQY74_RS20065	COG2732	(Barnase) inhibitor
EQY74_RS20070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EQY74_RS20075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS20080	COG1481	regulation of sporulation
EQY74_RS20085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EQY74_RS20090	COG1660	Displays ATPase and GTPase activities
EQY74_RS20095	COG1051	belongs to the nudix hydrolase family
EQY74_RS20105	COG0492	ferredoxin-NADP+ reductase activity
EQY74_RS20110	COG0457	Tetratricopeptide repeat
EQY74_RS20120	COG0140	phosphoribosyl-ATP diphosphatase activity
EQY74_RS20120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EQY74_RS20125	COG0107	imidazoleglycerol-phosphate synthase activity
EQY74_RS20130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EQY74_RS20135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EQY74_RS20140	COG0131	Imidazoleglycerol-phosphate dehydratase
EQY74_RS20145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EQY74_RS20150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EQY74_RS20155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EQY74_RS20160	COG4990	cell redox homeostasis
EQY74_RS20165	COG5297	Belongs to the glycosyl hydrolase family 6
EQY74_RS20170	COG0110	maltose O-acetyltransferase activity
EQY74_RS20175	COG0546	phosphoglycolate phosphatase activity
EQY74_RS20180	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EQY74_RS20185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EQY74_RS20190	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EQY74_RS20195	COG1846	Transcriptional regulator
EQY74_RS20200	COG2814	Major facilitator Superfamily
EQY74_RS20205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EQY74_RS20210	COG1950	PFAM Membrane protein of
EQY74_RS20215	COG1983	PspC domain protein
EQY74_RS20220	COG3595	metallopeptidase activity
EQY74_RS20245	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EQY74_RS20250	COG0556	nucleotide-excision repair
EQY74_RS20255	COG4897	Protein conserved in bacteria
EQY74_RS20265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQY74_RS20275	COG3409	Peptidoglycan-binding domain 1 protein
EQY74_RS20275	COG0793	Belongs to the peptidase S41A family
EQY74_RS20280	COG0473	3-isopropylmalate dehydrogenase activity
EQY74_RS20285	COG0791	NLP P60 protein
EQY74_RS20285	COG3883	PFAM NLP P60 protein
EQY74_RS20290	COG2177	Part of the ABC transporter FtsEX involved in
EQY74_RS20295	COG2884	Cell division ATP-binding protein ftsE
EQY74_RS20305	COG2010	Cytochrome c
EQY74_RS20310	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS20320	COG0653	protein targeting
EQY74_RS20325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EQY74_RS20340	COG1516	flagellar protein fliS
EQY74_RS20345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EQY74_RS20350	COG1334	flagellar protein FlaG
EQY74_RS20355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQY74_RS20360	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EQY74_RS20365	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EQY74_RS20375	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EQY74_RS20380	COG4786	Flagellar basal body rod
EQY74_RS20380	COG1256	bacterial-type flagellum assembly
EQY74_RS20385	COG3418	PFAM FlgN family protein
EQY74_RS20390	COG2747	anti-sigma28 factor FlgM
EQY74_RS20400	COG1040	competence protein
EQY74_RS20410	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EQY74_RS20415	COG1307	EDD domain protein, DegV family
EQY74_RS20420	COG2197	response regulator
EQY74_RS20425	COG4585	Histidine kinase
EQY74_RS20430	COG1739	Uncharacterized protein family UPF0029
EQY74_RS20435	COG1316	TRANSCRIPTIONal
EQY74_RS20445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EQY74_RS20450	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS20455	COG1215	transferase activity, transferring glycosyl groups
EQY74_RS20460	COG3206	protein involved in exopolysaccharide biosynthesis
EQY74_RS20465	COG3307	-O-antigen
EQY74_RS20470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EQY74_RS20475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EQY74_RS20480	COG0297	glycogen (starch) synthase activity
EQY74_RS20480	COG0438	transferase activity, transferring glycosyl groups
EQY74_RS20485	COG2244	polysaccharide biosynthetic process
EQY74_RS20495	COG2247	cell wall binding repeat
EQY74_RS20495	COG0860	N-Acetylmuramoyl-L-alanine amidase
EQY74_RS20500	COG2247	cell wall binding repeat
EQY74_RS20500	COG2385	sporulation resulting in formation of a cellular spore
EQY74_RS20510	COG1316	TRANSCRIPTIONal
EQY74_RS20515	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EQY74_RS20520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EQY74_RS20525	COG1134	teichoic acid transport
EQY74_RS20530	COG1682	transport, permease protein
EQY74_RS20535	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQY74_RS20535	COG0463	Glycosyl transferase, family 2
EQY74_RS20540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQY74_RS20545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EQY74_RS20550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EQY74_RS20555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EQY74_RS20560	COG4193	domain, Protein
EQY74_RS20565	COG1482	cell wall glycoprotein biosynthetic process
EQY74_RS20585	COG0800	Aldolase
EQY74_RS20590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQY74_RS20595	COG1609	Transcriptional regulator
EQY74_RS20600	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EQY74_RS20605	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS20610	COG1063	alcohol dehydrogenase
EQY74_RS20615	COG2814	Major facilitator Superfamily
EQY74_RS20620	COG1316	TRANSCRIPTIONal
EQY74_RS20625	COG0561	phosphatase activity
EQY74_RS20635	COG2843	Capsule synthesis protein
EQY74_RS20645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EQY74_RS20650	COG1609	Transcriptional regulator
EQY74_RS20655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQY74_RS20660	COG1869	D-ribose catabolic process
EQY74_RS20665	COG1129	ABC transporter
EQY74_RS20670	COG1172	Belongs to the binding-protein-dependent transport system permease family
EQY74_RS20675	COG1879	ABC-type sugar transport system periplasmic component
EQY74_RS20685	COG3527	Alpha-acetolactate decarboxylase
EQY74_RS20690	COG0028	Belongs to the TPP enzyme family
EQY74_RS20695	COG0583	DNA-binding transcription factor activity
EQY74_RS20705	COG0405	Gamma-glutamyltransferase
EQY74_RS20710	COG1522	sequence-specific DNA binding
EQY74_RS20715	COG2059	Chromate
EQY74_RS20720	COG2059	Chromate
EQY74_RS20725	COG4464	protein tyrosine phosphatase activity
EQY74_RS20730	COG3944	biosynthesis protein
EQY74_RS20740	COG4715	Zinc finger, swim domain protein
EQY74_RS20745	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EQY74_RS20750	COG0561	phosphatase activity
EQY74_RS20755	COG1349	DNA-binding transcription factor activity
EQY74_RS20765	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS20775	COG3732	PTS system glucitol sorbitol-specific
EQY74_RS20795	COG0629	single-stranded DNA binding
EQY74_RS20810	COG1970	mechanosensitive ion channel activity
EQY74_RS20815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EQY74_RS20820	COG4786	Flagellar basal body rod
EQY74_RS20825	COG4786	Flagellar basal body rod
EQY74_RS20830	COG1077	Cell shape determining protein MreB Mrl
EQY74_RS20835	COG1609	Transcriptional regulator
EQY74_RS20845	COG1846	Transcriptional regulator
EQY74_RS20850	COG2814	Major facilitator Superfamily
EQY74_RS20855	COG0671	phosphoesterase, PA-phosphatase related
EQY74_RS20860	COG1227	inorganic diphosphatase activity
EQY74_RS20865	COG3546	catalase activity
EQY74_RS20870	COG3361	conserved protein (COG2071)
EQY74_RS20875	COG0517	IMP dehydrogenase activity
EQY74_RS20880	COG0598	Magnesium transport protein CorA
EQY74_RS20885	COG1253	flavin adenine dinucleotide binding
EQY74_RS20890	COG0004	ammonium transporteR
EQY74_RS20895	COG0347	Belongs to the P(II) protein family
EQY74_RS20900	COG0740	serine-type endopeptidase activity
EQY74_RS20910	COG0739	heme binding
EQY74_RS20915	COG1247	-acetyltransferase
EQY74_RS20925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQY74_RS20930	COG0477	Major facilitator Superfamily
EQY74_RS20935	COG3251	PFAM MbtH domain protein
EQY74_RS20940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQY74_RS20945	COG1535	isochorismatase
EQY74_RS20945	COG3433	isochorismatase activity
EQY74_RS20950	COG1021	2,3-dihydroxybenzoate-AMP ligase
EQY74_RS20955	COG1169	isochorismate synthase
EQY74_RS20960	COG1028	Short-chain dehydrogenase reductase Sdr
EQY74_RS20965	COG2819	hydrolase of the alpha beta superfamily
EQY74_RS20970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS20975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EQY74_RS20980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS20985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS20985	COG2207	Transcriptional regulator
EQY74_RS20995	COG2910	NAD(P)H-binding
EQY74_RS21000	COG1959	2 iron, 2 sulfur cluster binding
EQY74_RS21010	COG1994	Peptidase M50
EQY74_RS21015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EQY74_RS21020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EQY74_RS21025	COG2223	nitrite transmembrane transporter activity
EQY74_RS21035	COG2304	oxidoreductase activity
EQY74_RS21040	COG2304	oxidoreductase activity
EQY74_RS21045	COG2385	sporulation resulting in formation of a cellular spore
EQY74_RS21050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQY74_RS21060	COG4836	Membrane
EQY74_RS21065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EQY74_RS21070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EQY74_RS21075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EQY74_RS21080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EQY74_RS21085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQY74_RS21090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EQY74_RS21095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EQY74_RS21115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EQY74_RS21120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EQY74_RS21125	COG4475	Protein of unknown function (DUF436)
EQY74_RS21130	COG0698	ribose 5-phosphate isomerase
EQY74_RS21135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EQY74_RS21140	COG1971	Probably functions as a manganese efflux pump
EQY74_RS21145	COG0009	L-threonylcarbamoyladenylate synthase
EQY74_RS21150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EQY74_RS21160	COG0738	Major facilitator superfamily
EQY74_RS21165	COG0673	inositol 2-dehydrogenase activity
EQY74_RS21170	COG0561	phosphatase activity
EQY74_RS21175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EQY74_RS21180	COG1609	Transcriptional regulator
EQY74_RS21185	COG2890	protein-(glutamine-N5) methyltransferase activity
EQY74_RS21190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EQY74_RS21195	COG0346	lactoylglutathione lyase activity
EQY74_RS21200	COG0789	Transcriptional regulator
EQY74_RS21205	COG0679	Auxin Efflux Carrier
EQY74_RS21210	COG0281	malic enzyme
EQY74_RS21215	COG1435	thymidine kinase activity
EQY74_RS21220	COG0254	rRNA binding
EQY74_RS21225	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EQY74_RS21230	COG1494	fructose-1,6-bisphosphatase
EQY74_RS21235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EQY74_RS21240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EQY74_RS21245	COG0191	fructose-bisphosphate aldolase activity
EQY74_RS21250	COG2204	response regulator
EQY74_RS21255	COG4821	SIS domain
EQY74_RS21260	COG0504	CTP synthase activity
EQY74_RS21265	COG3343	RNA polymerase activity
EQY74_RS21270	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS21275	COG1960	acyl-CoA dehydrogenase activity
EQY74_RS21280	COG1250	3-hydroxyacyl-CoA dehydrogenase
EQY74_RS21285	COG0183	Belongs to the thiolase family
EQY74_RS21290	COG0247	lactate metabolic process
EQY74_RS21290	COG2181	nitrate reductase activity
EQY74_RS21295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EQY74_RS21305	COG0018	arginyl-trna synthetase
EQY74_RS21310	COG4506	Protein conserved in bacteria
EQY74_RS21315	COG0010	Belongs to the arginase family
EQY74_RS21320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EQY74_RS21335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EQY74_RS21345	COG1994	Peptidase M50
EQY74_RS21350	COG1942	4-Oxalocrotonate Tautomerase
EQY74_RS21360	COG3465	dGTPase activity
EQY74_RS21365	COG1078	dGTPase activity
EQY74_RS21370	COG4844	belongs to the
EQY74_RS21395	COG2814	Major facilitator Superfamily
EQY74_RS21420	COG1414	Transcriptional regulator
EQY74_RS21430	COG0280	phosphate acetyltransferase
EQY74_RS21435	COG3253	May function as heme-dependent peroxidase
EQY74_RS21450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EQY74_RS21470	COG1131	(ABC) transporter
EQY74_RS21485	COG2363	Small membrane protein
EQY74_RS21490	COG2233	PERMEase
EQY74_RS21500	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS21505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EQY74_RS21510	COG1216	Glycosyl transferase, family 2
EQY74_RS21515	COG0351	phosphomethylpyrimidine kinase
EQY74_RS21525	COG1621	beta-fructofuranosidase activity
EQY74_RS21530	COG1263	PTS System
EQY74_RS21530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS21535	COG3711	transcriptional antiterminator
EQY74_RS21545	COG1404	Belongs to the peptidase S8 family
EQY74_RS21555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EQY74_RS21560	COG0778	Nitroreductase
EQY74_RS21565	COG1473	amidohydrolase
EQY74_RS21570	COG0772	Belongs to the SEDS family
EQY74_RS21575	COG0772	Belongs to the SEDS family
EQY74_RS21580	COG3314	Sporulation integral membrane protein YlbJ
EQY74_RS21600	COG0456	acetyltransferase
EQY74_RS21635	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EQY74_RS21645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EQY74_RS21650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EQY74_RS21655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQY74_RS21675	COG3162	membrane
EQY74_RS21680	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS21685	COG1070	Carbohydrate kinase
EQY74_RS21690	COG2115	Belongs to the xylose isomerase family
EQY74_RS21700	COG0352	thiamine-phosphate diphosphorylase activity
EQY74_RS21705	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EQY74_RS21710	COG0583	DNA-binding transcription factor activity
EQY74_RS21725	COG1380	Effector of murein hydrolase LrgA
EQY74_RS21730	COG1346	cytolysis
EQY74_RS21740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EQY74_RS21745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EQY74_RS21750	COG0346	lactoylglutathione lyase activity
EQY74_RS21755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EQY74_RS21760	COG1442	glycosyl transferase family 8
EQY74_RS21770	COG4585	Histidine kinase
EQY74_RS21775	COG2197	response regulator
EQY74_RS21780	COG2409	Drug exporters of the RND superfamily
EQY74_RS21785	COG5522	Integral membrane protein (intg_mem_TP0381)
EQY74_RS21790	COG2271	Major facilitator Superfamily
EQY74_RS21795	COG4948	Mandelate Racemase Muconate Lactonizing
EQY74_RS21800	COG0800	Aldolase
EQY74_RS21805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQY74_RS21815	COG2234	aminopeptidase activity
EQY74_RS21820	COG0477	Major facilitator Superfamily
EQY74_RS21830	COG2357	RelA SpoT domain protein
EQY74_RS21845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EQY74_RS21850	COG1696	Membrane protein involved in D-alanine export
EQY74_RS21855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EQY74_RS21860	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EQY74_RS21865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EQY74_RS21870	COG2814	Major facilitator Superfamily
EQY74_RS21875	COG1486	melibiose metabolic process
EQY74_RS21880	COG1447	Phosphotransferase system cellobiose-specific component IIA
EQY74_RS21885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS21890	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS21895	COG3711	transcriptional antiterminator
EQY74_RS21895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EQY74_RS21905	COG2094	Belongs to the DNA glycosylase MPG family
EQY74_RS21915	COG0372	Belongs to the citrate synthase family
EQY74_RS21920	COG2079	MmgE PrpD family protein
EQY74_RS21925	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EQY74_RS21940	COG1132	(ABC) transporter
EQY74_RS21945	COG2755	lipolytic protein G-D-S-L family
EQY74_RS21960	COG2814	Major facilitator Superfamily
EQY74_RS21965	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQY74_RS21970	COG1131	(ABC) transporter
EQY74_RS21990	COG1595	DNA-templated transcription, initiation
EQY74_RS21995	COG2814	Major facilitator Superfamily
EQY74_RS22000	COG0753	catalase activity
EQY74_RS22005	COG0753	catalase activity
EQY74_RS22010	COG0735	belongs to the Fur family
EQY74_RS22015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EQY74_RS22020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EQY74_RS22025	COG1131	(ABC) transporter
EQY74_RS22040	COG1131	(ABC) transporter
EQY74_RS22095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EQY74_RS22100	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EQY74_RS22105	COG4988	ABC transporter
EQY74_RS22110	COG1294	oxidase, subunit
EQY74_RS22115	COG1271	oxidase subunit
EQY74_RS22125	COG2116	formate transmembrane transporter activity
EQY74_RS22135	COG0281	malic enzyme
EQY74_RS22140	COG1757	Na H antiporter
EQY74_RS22145	COG1027	Aspartate ammonia-lyase
EQY74_RS22150	COG0252	asparaginase activity
EQY74_RS22155	COG1396	sequence-specific DNA binding
EQY74_RS22160	COG2706	6-phosphogluconolactonase activity
EQY74_RS22165	COG0745	RESPONSE REGULATOR receiver
EQY74_RS22170	COG2205	protein histidine kinase activity
EQY74_RS22180	COG1136	(ABC) transporter
EQY74_RS22185	COG0577	efflux transmembrane transporter activity
EQY74_RS22190	COG5294	Protein conserved in bacteria
EQY74_RS22200	COG0726	polysaccharide deacetylase
EQY74_RS22205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EQY74_RS22215	COG1215	transferase activity, transferring glycosyl groups
EQY74_RS22220	COG3493	citrate carrier protein
EQY74_RS22225	COG0584	glycerophosphoryl diester phosphodiesterase
EQY74_RS22240	COG1368	sulfuric ester hydrolase activity
EQY74_RS22250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EQY74_RS22265	COG2235	arginine
EQY74_RS22270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EQY74_RS22280	COG0549	Belongs to the carbamate kinase family
EQY74_RS22290	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS22295	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EQY74_RS22305	COG1595	DNA-templated transcription, initiation
EQY74_RS22330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EQY74_RS22335	COG2195	Cleaves the N-terminal amino acid of tripeptides
EQY74_RS22345	COG1621	beta-fructofuranosidase activity
EQY74_RS22350	COG2223	nitrite transmembrane transporter activity
EQY74_RS22355	COG1609	Transcriptional regulator
EQY74_RS22370	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EQY74_RS22375	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQY74_RS22380	COG0463	Glycosyl transferase, family 2
EQY74_RS22385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQY74_RS22390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQY74_RS22405	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS22410	COG1263	PTS System
EQY74_RS22410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS22410	COG2190	(PTS) system
EQY74_RS22415	COG3711	transcriptional antiterminator
EQY74_RS22420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EQY74_RS22425	COG1122	ATPase activity
EQY74_RS22430	COG4721	ABC-type cobalt transport system, permease component
EQY74_RS22435	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EQY74_RS22440	COG2224	Isocitrate lyase
EQY74_RS22445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EQY74_RS22455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EQY74_RS22460	COG0577	efflux transmembrane transporter activity
EQY74_RS22465	COG1136	(ABC) transporter
EQY74_RS22470	COG2205	protein histidine kinase activity
EQY74_RS22475	COG0745	RESPONSE REGULATOR receiver
EQY74_RS22480	COG2723	6-phospho-beta-galactosidase activity
EQY74_RS22485	COG1263	PTS System
EQY74_RS22485	COG2190	(PTS) system
EQY74_RS22485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS22495	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EQY74_RS22510	COG3507	Belongs to the glycosyl hydrolase 43 family
EQY74_RS22515	COG0513	Belongs to the DEAD box helicase family
EQY74_RS22545	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EQY74_RS22550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EQY74_RS22555	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EQY74_RS22560	COG2390	Transcriptional regulator
EQY74_RS22575	COG3706	GGDEF domain
EQY74_RS22580	COG5298	Protein conserved in bacteria
EQY74_RS22585	COG1215	transferase activity, transferring glycosyl groups
EQY74_RS22595	COG3977	Valine--pyruvate aminotransferase
EQY74_RS22610	COG1181	Belongs to the D-alanine--D-alanine ligase family
EQY74_RS22620	COG0191	fructose-bisphosphate aldolase activity
EQY74_RS22625	COG1082	Xylose isomerase domain protein TIM barrel
EQY74_RS22630	COG1082	Xylose isomerase domain protein TIM barrel
EQY74_RS22635	COG0673	inositol 2-dehydrogenase activity
EQY74_RS22640	COG2814	Major facilitator Superfamily
EQY74_RS22645	COG1082	Xylose isomerase domain protein TIM barrel
EQY74_RS22650	COG3962	Belongs to the TPP enzyme family
EQY74_RS22655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EQY74_RS22660	COG3718	enzyme involved in inositol metabolism
EQY74_RS22665	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS22670	COG1349	DNA-binding transcription factor activity
EQY74_RS22675	COG0667	Aldo Keto reductase
EQY74_RS22680	COG0584	glycerophosphoryl diester phosphodiesterase
EQY74_RS22685	COG2271	Major facilitator Superfamily
EQY74_RS22690	COG0326	Molecular chaperone. Has ATPase activity
EQY74_RS22695	COG0488	(ABC) transporter
EQY74_RS22700	COG0561	phosphatase activity
EQY74_RS22720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EQY74_RS22750	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EQY74_RS22755	COG0577	efflux transmembrane transporter activity
EQY74_RS22760	COG1136	(ABC) transporter
EQY74_RS22765	COG2205	protein histidine kinase activity
EQY74_RS22770	COG0745	RESPONSE REGULATOR receiver
EQY74_RS22780	COG0840	transmembrane signaling receptor activity
EQY74_RS22780	COG5278	phosphoserine phosphatase activity
EQY74_RS22785	COG1115	amino acid carrier protein
EQY74_RS22790	COG0686	Belongs to the AlaDH PNT family
EQY74_RS22795	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EQY74_RS22800	COG1874	Beta-galactosidase
EQY74_RS22805	COG3833	ABC-type maltose transport systems, permease component
EQY74_RS22810	COG1175	transmembrane transport
EQY74_RS22815	COG2182	Extracellular solute-binding protein
EQY74_RS22820	COG1609	Transcriptional regulator
EQY74_RS22830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EQY74_RS22835	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EQY74_RS22840	COG1940	carbohydrate kinase activity
EQY74_RS22865	COG1012	belongs to the aldehyde dehydrogenase family
EQY74_RS22865	COG1454	alcohol dehydrogenase
EQY74_RS22870	COG0450	alkyl hydroperoxide reductase
EQY74_RS22875	COG3634	alkyl hydroperoxide reductase activity
EQY74_RS22900	COG1131	(ABC) transporter
EQY74_RS22905	COG0842	Transport permease protein
EQY74_RS22915	COG2197	response regulator
EQY74_RS22940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EQY74_RS22955	COG0456	acetyltransferase
EQY74_RS22970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EQY74_RS22975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EQY74_RS22980	COG4853	Protein conserved in bacteria
EQY74_RS22985	COG4863	YycH protein
EQY74_RS22990	COG5002	protein histidine kinase activity
EQY74_RS22995	COG0745	RESPONSE REGULATOR receiver
EQY74_RS23020	COG1051	belongs to the nudix hydrolase family
EQY74_RS23025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EQY74_RS23035	COG0305	Participates in initiation and elongation during chromosome replication
EQY74_RS23050	COG3093	addiction module antidote protein HigA
EQY74_RS23055	COG2807	transmembrane transport
EQY74_RS23060	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EQY74_RS23065	COG0363	glucosamine-6-phosphate deaminase activity
EQY74_RS23070	COG2188	Transcriptional regulator
EQY74_RS23075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EQY74_RS23080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EQY74_RS23080	COG1263	PTS System
EQY74_RS23085	COG0359	binds to the 23S rRNA
EQY74_RS23090	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EQY74_RS23095	COG4241	membrane
EQY74_RS23100	COG5577	PFAM Coat F domain
EQY74_RS23105	COG0589	response to stress
EQY74_RS23110	COG0659	secondary active sulfate transmembrane transporter activity
EQY74_RS23115	COG2271	Major facilitator Superfamily
EQY74_RS23120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EQY74_RS23125	COG0629	single-stranded DNA binding
EQY74_RS23130	COG0360	Binds together with S18 to 16S ribosomal RNA
EQY74_RS23135	COG0012	GTP binding
EQY74_RS23145	COG4481	Protein conserved in bacteria
EQY74_RS23150	COG3949	Membrane
EQY74_RS23160	COG1475	DNA binding
EQY74_RS23165	COG1192	Involved in chromosome partitioning
EQY74_RS23170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EQY74_RS23180	COG1475	DNA binding
EQY74_RS23185	COG0357	Ribosomal RNA small subunit methyltransferase G
EQY74_RS23190	COG0445	tRNA wobble uridine modification
EQY74_RS23195	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EQY74_RS23200	COG1847	R3H domain protein
EQY74_RS23205	COG0706	membrane insertase activity
EQY74_RS23210	COG0594	ribonuclease P activity
EQY74_RS23320	COG0791	NLP P60 protein
EQY74_RS23320	COG3883	PFAM NLP P60 protein
EQY74_RS23355	COG0629	single-stranded DNA binding
EQY74_RS23540	COG5444	nuclease activity
EQY74_RS23545	COG0457	Tetratricopeptide repeat
EQY74_RS23590	COG1793	dna ligase
EQY74_RS23625	COG1192	Involved in chromosome partitioning
EQY74_RS23635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EQY74_RS23645	COG1396	sequence-specific DNA binding
EQY74_RS23670	COG3764	Sortase (surface protein transpeptidase)