locus-tag	class	description
ETA57_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETA57_RS00010	COG0592	DNA-directed DNA polymerase activity
ETA57_RS00015	COG2501	S4 domain
ETA57_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETA57_RS00030	COG0187	DNA topoisomerase II activity
ETA57_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETA57_RS00070	COG0517	IMP dehydrogenase activity
ETA57_RS00070	COG0516	GMP reductase activity
ETA57_RS00075	COG1686	Belongs to the peptidase S11 family
ETA57_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ETA57_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ETA57_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETA57_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
ETA57_RS00100	COG2610	gluconate transmembrane transporter activity
ETA57_RS00105	COG3835	regulator
ETA57_RS00120	COG1428	Deoxynucleoside kinase
ETA57_RS00125	COG1428	Deoxynucleoside kinase
ETA57_RS00130	COG1388	LysM domain
ETA57_RS00130	COG3858	chitin binding
ETA57_RS00135	COG1335	isochorismatase
ETA57_RS00140	COG0590	tRNA wobble adenosine to inosine editing
ETA57_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETA57_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ETA57_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETA57_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ETA57_RS00210	COG3853	Toxic anion resistance protein (TelA)
ETA57_RS00215	COG1982	Orn Lys Arg decarboxylase major
ETA57_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETA57_RS00225	COG3870	Protein conserved in bacteria
ETA57_RS00230	COG1728	Protein conserved in bacteria
ETA57_RS00235	COG0470	DNA polymerase III
ETA57_RS00240	COG1774	PSP1 C-terminal conserved region
ETA57_RS00245	COG4467	Involved in initiation control of chromosome replication
ETA57_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETA57_RS00255	COG2827	Endonuclease containing a URI domain
ETA57_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ETA57_RS00265	COG2002	toxin-antitoxin pair type II binding
ETA57_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA57_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA57_RS00275	COG0084	hydrolase, TatD family'
ETA57_RS00280	COG3583	domain protein
ETA57_RS00280	COG3584	3D domain protein
ETA57_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETA57_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETA57_RS00300	COG4466	Protein conserved in bacteria
ETA57_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETA57_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA57_RS00320	COG0251	oxidation-reduction process
ETA57_RS00325	COG2088	sporulation resulting in formation of a cellular spore
ETA57_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETA57_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETA57_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETA57_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
ETA57_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETA57_RS00360	COG2002	toxin-antitoxin pair type II binding
ETA57_RS00365	COG2244	polysaccharide biosynthetic process
ETA57_RS00370	COG3956	TIGRFAM MazG family protein
ETA57_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETA57_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ETA57_RS00395	COG1098	S1 RNA binding domain
ETA57_RS00410	COG2208	phosphoserine phosphatase activity
ETA57_RS00415	COG2304	oxidoreductase activity
ETA57_RS00420	COG0515	serine threonine protein kinase
ETA57_RS00425	COG0037	tRNA processing
ETA57_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETA57_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETA57_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETA57_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ETA57_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETA57_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA57_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETA57_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
ETA57_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA57_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETA57_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ETA57_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETA57_RS00495	COG1396	sequence-specific DNA binding
ETA57_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETA57_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ETA57_RS00585	COG4463	regulation of RNA biosynthetic process
ETA57_RS00590	COG3880	PFAM UvrB UvrC protein
ETA57_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETA57_RS00600	COG0542	response to heat
ETA57_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETA57_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ETA57_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
ETA57_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETA57_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETA57_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETA57_RS00635	COG1045	serine acetyltransferase
ETA57_RS00640	COG0215	cysteine-tRNA ligase activity
ETA57_RS00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETA57_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETA57_RS00655	COG3688	RNA-binding protein containing a PIN domain
ETA57_RS00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETA57_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
ETA57_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETA57_RS00685	COG0081	regulation of translation
ETA57_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETA57_RS00695	COG0222	ribosome binding
ETA57_RS00700	COG2813	Specifically methylates the guanine in position
ETA57_RS00705	COG0085	RNA polymerase activity
ETA57_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETA57_RS00715	COG1358	cellular component organization or biogenesis
ETA57_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETA57_RS00725	COG0049	tRNA binding
ETA57_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETA57_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETA57_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETA57_RS00750	COG0088	Forms part of the polypeptide exit tunnel
ETA57_RS00755	COG0089	rRNA binding
ETA57_RS00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETA57_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETA57_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETA57_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETA57_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETA57_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
ETA57_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETA57_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETA57_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ETA57_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETA57_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETA57_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETA57_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETA57_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETA57_RS00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETA57_RS00835	COG1841	ribosomal large subunit assembly
ETA57_RS00840	COG0200	Binds to the 23S rRNA
ETA57_RS00845	COG0201	protein transport
ETA57_RS00850	COG0563	adenylate kinase activity
ETA57_RS00855	COG0024	Methionine aminopeptidase
ETA57_RS00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
ETA57_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETA57_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ETA57_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETA57_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETA57_RS00885	COG0202	RNA polymerase activity
ETA57_RS00890	COG0203	ribosomal protein L17
ETA57_RS00895	COG1122	ATPase activity
ETA57_RS00900	COG1122	ATPase activity
ETA57_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETA57_RS00910	COG0101	tRNA pseudouridine synthase activity
ETA57_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETA57_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETA57_RS00925	COG2318	DinB family
ETA57_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS00940	COG0489	protein tyrosine kinase activity
ETA57_RS00950	COG2194	sulfuric ester hydrolase activity
ETA57_RS00955	COG0726	polysaccharide deacetylase
ETA57_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA57_RS00995	COG0385	Bile acid
ETA57_RS01010	COG3876	Protein conserved in bacteria
ETA57_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
ETA57_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA57_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS01025	COG1263	PTS System
ETA57_RS01030	COG1737	Transcriptional regulator
ETA57_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETA57_RS01040	COG1683	Conserved Protein
ETA57_RS01075	COG1595	DNA-templated transcription, initiation
ETA57_RS01080	COG5662	AntiSigma factor
ETA57_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETA57_RS01090	COG4856	YbbR-like protein
ETA57_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETA57_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETA57_RS01130	COG1063	alcohol dehydrogenase
ETA57_RS01140	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS01170	COG1725	Transcriptional regulator
ETA57_RS01175	COG0640	Transcriptional regulator
ETA57_RS01180	COG2814	Major facilitator Superfamily
ETA57_RS01190	COG1132	(ABC) transporter
ETA57_RS01195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETA57_RS01220	COG1011	Hydrolase
ETA57_RS01225	COG1113	amino acid transport
ETA57_RS01230	COG2851	Citrate transporter
ETA57_RS01235	COG3181	Tripartite tricarboxylate transporter family receptor
ETA57_RS01240	COG4565	transcriptional regulatory protein
ETA57_RS01245	COG3290	protein histidine kinase activity
ETA57_RS01260	COG2211	Major facilitator Superfamily
ETA57_RS01295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA57_RS01300	COG1331	Highly conserved protein containing a thioredoxin domain
ETA57_RS01305	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ETA57_RS01310	COG1331	Highly conserved protein containing a thioredoxin domain
ETA57_RS01320	COG0477	Major facilitator Superfamily
ETA57_RS01340	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETA57_RS01345	COG4682	membrane
ETA57_RS01370	COG0697	spore germination
ETA57_RS01375	COG1917	Cupin 2, conserved barrel domain protein
ETA57_RS01375	COG2207	Transcriptional regulator
ETA57_RS01395	COG0371	Dehydrogenase
ETA57_RS01405	COG4213	ABC transporter substrate-binding protein
ETA57_RS01420	COG4257	antibiotic catabolic process
ETA57_RS01435	COG2040	homocysteine
ETA57_RS01445	COG1263	PTS System
ETA57_RS01445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS01445	COG2190	(PTS) system
ETA57_RS01450	COG0789	Transcriptional regulator
ETA57_RS01455	COG2323	membrane
ETA57_RS01460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETA57_RS01460	COG4451	ribulose bisphosphate carboxylase, small
ETA57_RS01470	COG2205	protein histidine kinase activity
ETA57_RS01475	COG1115	amino acid carrier protein
ETA57_RS01480	COG2066	Belongs to the glutaminase family
ETA57_RS01485	COG4191	Histidine kinase
ETA57_RS01490	COG0784	Response regulator, receiver
ETA57_RS01515	COG3540	Alkaline phosphatase
ETA57_RS01520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETA57_RS01525	COG0805	protein transport
ETA57_RS01530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETA57_RS01535	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS01540	COG2271	Major facilitator Superfamily
ETA57_RS01545	COG4948	Mandelate Racemase Muconate Lactonizing
ETA57_RS01550	COG2186	Transcriptional regulator
ETA57_RS01555	COG2721	sulfolactate sulfo-lyase activity
ETA57_RS01560	COG0745	RESPONSE REGULATOR receiver
ETA57_RS01565	COG2205	protein histidine kinase activity
ETA57_RS01570	COG1131	(ABC) transporter
ETA57_RS01595	COG3173	Aminoglycoside phosphotransferase
ETA57_RS01600	COG1846	Transcriptional regulator
ETA57_RS01605	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS01625	COG0789	Transcriptional regulator
ETA57_RS01650	COG0697	spore germination
ETA57_RS01655	COG1714	RDD family
ETA57_RS01660	COG3012	SEC-C Motif Domain Protein
ETA57_RS01660	COG1405	negative regulation of cell septum assembly
ETA57_RS01665	COG1131	(ABC) transporter
ETA57_RS01690	COG0583	DNA-binding transcription factor activity
ETA57_RS01695	COG1942	4-Oxalocrotonate Tautomerase
ETA57_RS01700	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS01705	COG2226	methyltransferase
ETA57_RS01715	COG1288	antiporter activity
ETA57_RS01725	COG0456	acetyltransferase
ETA57_RS01735	COG1164	Oligoendopeptidase f
ETA57_RS01740	COG2261	transglycosylase associated protein
ETA57_RS01750	COG0247	lactate metabolic process
ETA57_RS01755	COG0277	FAD linked oxidase domain protein
ETA57_RS01760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS01765	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETA57_RS01770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS01775	COG1486	melibiose metabolic process
ETA57_RS01780	COG2188	Transcriptional regulator
ETA57_RS01785	COG3394	polysaccharide catabolic process
ETA57_RS01800	COG3591	Belongs to the peptidase S1B family
ETA57_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS01815	COG1595	DNA-templated transcription, initiation
ETA57_RS01825	COG3773	Cell wall hydrolase
ETA57_RS01830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA57_RS01835	COG0791	NLP P60 protein
ETA57_RS01835	COG3883	PFAM NLP P60 protein
ETA57_RS01845	COG1131	(ABC) transporter
ETA57_RS01850	COG1309	transcriptional regulator
ETA57_RS01870	COG2310	stress, protein
ETA57_RS01875	COG2310	stress, protein
ETA57_RS01880	COG2310	stress, protein
ETA57_RS01885	COG0861	Integral membrane protein TerC family
ETA57_RS01905	COG3853	Toxic anion resistance protein (TelA)
ETA57_RS01910	COG0785	Cytochrome C biogenesis protein
ETA57_RS01920	COG0789	Transcriptional regulator
ETA57_RS01925	COG2223	nitrite transmembrane transporter activity
ETA57_RS01930	COG0039	L-malate dehydrogenase activity
ETA57_RS01935	COG1620	l-lactate permease
ETA57_RS01940	COG1280	lysine exporter protein (LysE YggA)
ETA57_RS01945	COG1113	amino acid transport
ETA57_RS01950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETA57_RS01955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETA57_RS01960	COG3541	Predicted nucleotidyltransferase
ETA57_RS01965	COG0506	proline dehydrogenase activity
ETA57_RS01970	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS01980	COG2508	Transcriptional regulator
ETA57_RS01985	COG3689	TIGRFAM TIGR03943 family protein
ETA57_RS01990	COG0701	Predicted permease
ETA57_RS01995	COG3458	cephalosporin-C deacetylase activity
ETA57_RS02015	COG0765	amino acid transport
ETA57_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA57_RS02025	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS02035	COG2723	6-phospho-beta-galactosidase activity
ETA57_RS02045	COG3209	COG3209 Rhs family protein
ETA57_RS02050	COG0515	serine threonine protein kinase
ETA57_RS02050	COG3266	domain, Protein
ETA57_RS02060	COG5444	nuclease activity
ETA57_RS02085	COG1176	ABC-type spermidine putrescine transport system, permease component I
ETA57_RS02095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA57_RS02100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA57_RS02105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA57_RS02110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ETA57_RS02115	COG0697	spore germination
ETA57_RS02120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA57_RS02130	COG2819	hydrolase of the alpha beta superfamily
ETA57_RS02140	COG2364	Membrane
ETA57_RS02150	COG1131	(ABC) transporter
ETA57_RS02175	COG1126	abc transporter atp-binding protein
ETA57_RS02180	COG0765	amino acid transport
ETA57_RS02185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA57_RS02190	COG3829	transcription factor binding
ETA57_RS02195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETA57_RS02200	COG0833	amino acid
ETA57_RS02205	COG0010	Belongs to the arginase family
ETA57_RS02210	COG0583	DNA-binding transcription factor activity
ETA57_RS02215	COG0163	prenyltransferase activity
ETA57_RS02220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ETA57_RS02270	COG5444	nuclease activity
ETA57_RS02290	COG2972	Histidine kinase
ETA57_RS02295	COG2207	Transcriptional regulator
ETA57_RS02295	COG4753	response regulator
ETA57_RS02300	COG4213	ABC transporter substrate-binding protein
ETA57_RS02310	COG4214	carbohydrate transport
ETA57_RS02315	COG2271	Major facilitator Superfamily
ETA57_RS02320	COG0456	acetyltransferase
ETA57_RS02320	COG1846	Transcriptional regulator
ETA57_RS02330	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
ETA57_RS02335	COG3104	oligopeptide transport
ETA57_RS02340	COG5434	Belongs to the glycosyl hydrolase 28 family
ETA57_RS02350	COG0697	spore germination
ETA57_RS02360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ETA57_RS02365	COG0789	Transcriptional regulator
ETA57_RS02370	COG1136	(ABC) transporter
ETA57_RS02375	COG0577	efflux transmembrane transporter activity
ETA57_RS02380	COG0745	RESPONSE REGULATOR receiver
ETA57_RS02385	COG5002	protein histidine kinase activity
ETA57_RS02385	COG3850	Histidine kinase
ETA57_RS02395	COG0527	aspartate kinase activity
ETA57_RS02400	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS02405	COG4605	iron ion homeostasis
ETA57_RS02410	COG4604	ABC transporter, ATP-binding protein
ETA57_RS02415	COG4607	ABC-type enterochelin transport system periplasmic component
ETA57_RS02420	COG2814	Major facilitator Superfamily
ETA57_RS02425	COG1309	transcriptional regulator
ETA57_RS02435	COG0778	Nitroreductase
ETA57_RS02440	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETA57_RS02445	COG0640	Transcriptional regulator
ETA57_RS02450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA57_RS02455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETA57_RS02460	COG0531	amino acid
ETA57_RS02465	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS02475	COG0697	spore germination
ETA57_RS02485	COG4549	nuclear export factor GLE1
ETA57_RS02490	COG2372	response to copper ion
ETA57_RS02490	COG1276	copper resistance
ETA57_RS02495	COG1349	DNA-binding transcription factor activity
ETA57_RS02500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA57_RS02505	COG0243	molybdopterin cofactor binding
ETA57_RS02510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA57_RS02515	COG2146	nitrite reductase [NAD(P)H] activity
ETA57_RS02520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETA57_RS02520	COG1587	Uroporphyrinogen-III synthase
ETA57_RS02525	COG1802	Transcriptional regulator
ETA57_RS02530	COG0471	metal ion transport
ETA57_RS02535	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETA57_RS02540	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETA57_RS02555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS02570	COG3959	Transketolase, thiamine diphosphate binding domain
ETA57_RS02580	COG0561	phosphatase activity
ETA57_RS02590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ETA57_RS02595	COG1914	H( )-stimulated, divalent metal cation uptake system
ETA57_RS02600	COG4336	lyase activity
ETA57_RS02605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ETA57_RS02610	COG1984	allophanate hydrolase subunit 2
ETA57_RS02615	COG1414	Transcriptional regulator
ETA57_RS02620	COG2755	lipolytic protein G-D-S-L family
ETA57_RS02625	COG2213	PTS system mannitol-specific
ETA57_RS02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS02635	COG0246	Mannitol dehydrogenase
ETA57_RS02640	COG3711	transcriptional antiterminator
ETA57_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS02650	COG1917	Cupin 2, conserved barrel domain protein
ETA57_RS02660	COG3871	stress protein (general stress protein 26)
ETA57_RS02675	COG2814	Major facilitator Superfamily
ETA57_RS02685	COG1522	sequence-specific DNA binding
ETA57_RS02690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETA57_RS02690	COG0551	DNA topoisomerase type I activity
ETA57_RS02695	COG0531	amino acid
ETA57_RS02700	COG0028	Belongs to the TPP enzyme family
ETA57_RS02705	COG3397	chitin binding
ETA57_RS02715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA57_RS02720	COG1914	H( )-stimulated, divalent metal cation uptake system
ETA57_RS02725	COG2261	transglycosylase associated protein
ETA57_RS02730	COG1027	Aspartate ammonia-lyase
ETA57_RS02735	COG1819	glycosyl
ETA57_RS02740	COG4876	unkown
ETA57_RS02745	COG2217	Heavy metal translocating P-type atpase
ETA57_RS02755	COG0662	Cupin 2, conserved barrel domain protein
ETA57_RS02760	COG3729	General stress protein
ETA57_RS02765	COG0628	permease
ETA57_RS02770	COG1301	dicarboxylic acid transport
ETA57_RS02775	COG1131	(ABC) transporter
ETA57_RS02780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA57_RS02790	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS02805	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS02810	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETA57_RS02815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETA57_RS02825	COG0513	Belongs to the DEAD box helicase family
ETA57_RS02830	COG3402	PFAM membrane-flanked domain
ETA57_RS02835	COG3428	Bacterial PH domain
ETA57_RS02840	COG0705	Rhomboid family
ETA57_RS02845	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ETA57_RS02850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETA57_RS02855	COG0864	Transcriptional regulator
ETA57_RS02860	COG2337	Toxic component of a toxin-antitoxin (TA) module
ETA57_RS02865	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA57_RS02870	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA57_RS02875	COG2172	sigma factor antagonist activity
ETA57_RS02880	COG2208	phosphoserine phosphatase activity
ETA57_RS02890	COG2172	sigma factor antagonist activity
ETA57_RS02895	COG1191	sigma factor activity
ETA57_RS02900	COG2208	phosphoserine phosphatase activity
ETA57_RS02905	COG2183	response to ionizing radiation
ETA57_RS02910	COG1309	transcriptional regulator
ETA57_RS02915	COG2409	Drug exporters of the RND superfamily
ETA57_RS02915	COG1033	growth of symbiont in host cell
ETA57_RS02925	COG3091	SprT-like family
ETA57_RS02965	COG0582	viral genome integration into host DNA
ETA57_RS02970	COG2856	Zn peptidase
ETA57_RS02975	COG1396	sequence-specific DNA binding
ETA57_RS03010	COG1674	ftsk spoiiie
ETA57_RS03015	COG1674	ftsk spoiiie
ETA57_RS03020	COG2946	Replication initiation factor
ETA57_RS03055	COG0433	COG0433 Predicted ATPase
ETA57_RS03065	COG5644	endopeptidase inhibitor activity
ETA57_RS03070	COG0791	NLP P60 protein
ETA57_RS03070	COG0741	lytic transglycosylase activity
ETA57_RS03085	COG0457	Tetratricopeptide repeat
ETA57_RS03135	COG1476	TRANSCRIPTIONal
ETA57_RS03140	COG3239	Fatty acid desaturase
ETA57_RS03145	COG1278	Cold shock
ETA57_RS03160	COG2364	Membrane
ETA57_RS03165	COG1846	Transcriptional regulator
ETA57_RS03170	COG0456	acetyltransferase
ETA57_RS03175	COG2808	Putative FMN-binding domain
ETA57_RS03185	COG1733	regulation of RNA biosynthetic process
ETA57_RS03190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS03215	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ETA57_RS03220	COG1113	amino acid transport
ETA57_RS03235	COG1595	DNA-templated transcription, initiation
ETA57_RS03245	COG2755	lipolytic protein G-D-S-L family
ETA57_RS03245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETA57_RS03250	COG2814	Major facilitator Superfamily
ETA57_RS03255	COG0745	RESPONSE REGULATOR receiver
ETA57_RS03255	COG2972	Histidine kinase
ETA57_RS03260	COG3279	Response regulator of the LytR AlgR family
ETA57_RS03270	COG3764	Sortase (surface protein transpeptidase)
ETA57_RS03280	COG2814	Major facilitator Superfamily
ETA57_RS03320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETA57_RS03325	COG0802	atpase or kinase
ETA57_RS03330	COG1214	PFAM Peptidase M22, glycoprotease
ETA57_RS03335	COG0456	acetyltransferase
ETA57_RS03340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETA57_RS03345	COG0488	(ABC) transporter
ETA57_RS03350	COG0315	cyclic pyranopterin monophosphate synthase activity
ETA57_RS03355	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETA57_RS03360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETA57_RS03365	COG0805	protein transport
ETA57_RS03375	COG1266	CAAX protease self-immunity
ETA57_RS03380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETA57_RS03385	COG0459	protein refolding
ETA57_RS03420	COG2720	vancomycin resistance protein
ETA57_RS03435	COG2135	peptidase activity
ETA57_RS03445	COG1309	transcriptional regulator
ETA57_RS03450	COG3848	Pyruvate phosphate dikinase
ETA57_RS03450	COG0574	Belongs to the PEP-utilizing enzyme family
ETA57_RS03460	COG3189	MarR family transcriptional regulator
ETA57_RS03465	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
ETA57_RS03470	COG2272	Belongs to the type-B carboxylesterase lipase family
ETA57_RS03475	COG2814	Major facilitator Superfamily
ETA57_RS03480	COG1842	Phage shock protein A
ETA57_RS03485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETA57_RS03490	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ETA57_RS03495	COG4260	virion core protein, lumpy skin disease virus
ETA57_RS03505	COG1378	Sugar-specific transcriptional regulator TrmB
ETA57_RS03510	COG1280	lysine exporter protein (LysE YggA)
ETA57_RS03515	COG3339	Conserved Protein
ETA57_RS03525	COG0772	Belongs to the SEDS family
ETA57_RS03550	COG0726	polysaccharide deacetylase
ETA57_RS03560	COG1609	Transcriptional regulator
ETA57_RS03565	COG0366	Alpha amylase catalytic
ETA57_RS03570	COG2182	Extracellular solute-binding protein
ETA57_RS03575	COG1175	transmembrane transport
ETA57_RS03580	COG3833	ABC-type maltose transport systems, permease component
ETA57_RS03585	COG5521	maltodextrose utilization protein MalA
ETA57_RS03590	COG1554	hydrolase, family 65, central catalytic
ETA57_RS03595	COG0366	Alpha amylase catalytic
ETA57_RS03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETA57_RS03605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETA57_RS03610	COG1846	Transcriptional regulator
ETA57_RS03625	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETA57_RS03630	COG0823	Involved in the tonB-independent uptake of proteins
ETA57_RS03660	COG0702	epimerase
ETA57_RS03670	COG2132	Multicopper oxidase
ETA57_RS03690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETA57_RS03695	COG0714	Associated with various cellular activities
ETA57_RS03700	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ETA57_RS03705	COG1305	Transglutaminase-like
ETA57_RS03710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETA57_RS03710	COG0519	Catalyzes the synthesis of GMP from XMP
ETA57_RS03720	COG2252	PERMEase
ETA57_RS03735	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ETA57_RS03745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETA57_RS03750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETA57_RS03755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETA57_RS03760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETA57_RS03765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETA57_RS03770	COG0047	phosphoribosylformylglycinamidine synthase activity
ETA57_RS03775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETA57_RS03780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETA57_RS03785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETA57_RS03790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETA57_RS03795	COG0138	bifunctional purine biosynthesis protein purh
ETA57_RS03800	COG0151	Belongs to the GarS family
ETA57_RS03810	COG2124	cytochrome p450
ETA57_RS03830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETA57_RS03835	COG1470	cell adhesion involved in biofilm formation
ETA57_RS03840	COG4496	protein, YerC YecD
ETA57_RS03845	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ETA57_RS03850	COG0210	DNA helicase
ETA57_RS03855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETA57_RS03860	COG4851	CamS sex pheromone cAM373 precursor
ETA57_RS03865	COG2188	Transcriptional regulator
ETA57_RS03885	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ETA57_RS03890	COG0626	cystathionine gamma-synthase activity
ETA57_RS03895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETA57_RS03900	COG3457	Alanine racemase
ETA57_RS03905	COG0363	glucosamine-6-phosphate deaminase activity
ETA57_RS03910	COG1285	pathogenesis
ETA57_RS03915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA57_RS03920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETA57_RS03925	COG0154	amidase activity
ETA57_RS03930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETA57_RS03945	COG4124	Belongs to the glycosyl hydrolase 26 family
ETA57_RS03950	COG1309	transcriptional regulator
ETA57_RS03955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETA57_RS03965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA57_RS03970	COG1957	nucleoside hydrolase
ETA57_RS03975	COG1597	lipid kinase activity
ETA57_RS03980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETA57_RS03990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS03990	COG1263	PTS System
ETA57_RS03990	COG2190	(PTS) system
ETA57_RS03995	COG2723	6-phospho-beta-galactosidase activity
ETA57_RS04000	COG3711	transcriptional antiterminator
ETA57_RS04025	COG0217	transcriptional regulatory protein
ETA57_RS04040	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS04045	COG0840	transmembrane signaling receptor activity
ETA57_RS04050	COG0471	metal ion transport
ETA57_RS04055	COG0488	(ABC) transporter
ETA57_RS04065	COG1469	GTP cyclohydrolase I activity
ETA57_RS04080	COG0523	cobalamin synthesis protein
ETA57_RS04085	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ETA57_RS04090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETA57_RS04095	COG0156	8-amino-7-oxononanoate synthase activity
ETA57_RS04100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ETA57_RS04105	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETA57_RS04110	COG2124	cytochrome p450
ETA57_RS04120	COG0789	Transcriptional regulator
ETA57_RS04125	COG2814	Major facilitator Superfamily
ETA57_RS04135	COG0488	(ABC) transporter
ETA57_RS04140	COG0513	Belongs to the DEAD box helicase family
ETA57_RS04145	COG2130	NADP-dependent
ETA57_RS04160	COG0471	metal ion transport
ETA57_RS04175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS04185	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ETA57_RS04190	COG5658	integral membrane protein
ETA57_RS04195	COG0640	Transcriptional regulator
ETA57_RS04200	COG1254	Belongs to the acylphosphatase family
ETA57_RS04205	COG2258	MOSC domain
ETA57_RS04215	COG0024	Methionine aminopeptidase
ETA57_RS04220	COG1368	sulfuric ester hydrolase activity
ETA57_RS04235	COG1263	PTS System
ETA57_RS04235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS04240	COG0366	Alpha amylase catalytic
ETA57_RS04245	COG2188	Transcriptional regulator
ETA57_RS04270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA57_RS04275	COG1045	serine acetyltransferase
ETA57_RS04280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA57_RS04290	COG1215	transferase activity, transferring glycosyl groups
ETA57_RS04295	COG0457	Tetratricopeptide repeat
ETA57_RS04295	COG0463	Glycosyl transferase, family 2
ETA57_RS04305	COG0673	inositol 2-dehydrogenase activity
ETA57_RS04315	COG0657	acetylesterase activity
ETA57_RS04320	COG1733	regulation of RNA biosynthetic process
ETA57_RS04325	COG0778	Nitroreductase
ETA57_RS04330	COG0737	Belongs to the 5'-nucleotidase family
ETA57_RS04335	COG0693	protein deglycase activity
ETA57_RS04345	COG4840	Belongs to the UPF0435 family
ETA57_RS04350	COG1115	amino acid carrier protein
ETA57_RS04355	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA57_RS04360	COG4980	gas vesicle protein
ETA57_RS04365	COG1295	ribonuclease BN
ETA57_RS04370	COG0477	Major facilitator Superfamily
ETA57_RS04380	COG0387	Pfam Sodium calcium exchanger
ETA57_RS04390	COG0535	radical SAM domain protein
ETA57_RS04400	COG0726	polysaccharide deacetylase
ETA57_RS04405	COG0371	Dehydrogenase
ETA57_RS04415	COG0598	Magnesium transport protein CorA
ETA57_RS04420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ETA57_RS04425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ETA57_RS04430	COG4637	Psort location Cytoplasmic, score
ETA57_RS04455	COG1819	glycosyl
ETA57_RS04465	COG0477	Major facilitator Superfamily
ETA57_RS04470	COG1263	PTS System
ETA57_RS04470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS04475	COG3711	transcriptional antiterminator
ETA57_RS04480	COG0288	reversible hydration of carbon dioxide
ETA57_RS04485	COG3002	Belongs to the UPF0753 family
ETA57_RS04490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETA57_RS04495	COG5609	conserved protein (DUF2294)
ETA57_RS04505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA57_RS04510	COG0022	dehydrogenase e1 component
ETA57_RS04515	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA57_RS04520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA57_RS04525	COG3284	Transcriptional regulator
ETA57_RS04530	COG1742	UPF0060 membrane protein
ETA57_RS04535	COG1486	melibiose metabolic process
ETA57_RS04540	COG1737	Transcriptional regulator
ETA57_RS04545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS04545	COG1263	PTS System
ETA57_RS04560	COG1733	regulation of RNA biosynthetic process
ETA57_RS04565	COG2259	Doxx family
ETA57_RS04570	COG2514	catechol 2,3-dioxygenase activity
ETA57_RS04580	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA57_RS04585	COG2207	Transcriptional regulator
ETA57_RS04585	COG1917	Cupin 2, conserved barrel domain protein
ETA57_RS04595	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS04600	COG1051	belongs to the nudix hydrolase family
ETA57_RS04610	COG0392	lysyltransferase activity
ETA57_RS04610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ETA57_RS04615	COG0384	phenazine biosynthesis protein PhzF
ETA57_RS04620	COG0778	Nitroreductase
ETA57_RS04640	COG1090	epimerase
ETA57_RS04645	COG2137	regulation of response to DNA damage stimulus
ETA57_RS04675	COG0463	Glycosyl transferase, family 2
ETA57_RS04685	COG4485	Bacterial membrane protein, YfhO
ETA57_RS04690	COG1988	membrane-bound metal-dependent
ETA57_RS04695	COG1194	a g-specific adenine glycosylase
ETA57_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS04720	COG3557	Belongs to the UPF0374 family
ETA57_RS04725	COG1132	(ABC) transporter
ETA57_RS04730	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS04735	COG4608	Belongs to the ABC transporter superfamily
ETA57_RS04740	COG0747	negative chemotaxis
ETA57_RS04745	COG0601	transmembrane transport
ETA57_RS04750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS04755	COG4129	membrane
ETA57_RS04760	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETA57_RS04765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETA57_RS04770	COG0735	belongs to the Fur family
ETA57_RS04875	COG4974	Belongs to the 'phage' integrase family
ETA57_RS04985	COG1396	sequence-specific DNA binding
ETA57_RS05030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ETA57_RS05055	COG1780	Probably involved in ribonucleotide reductase function
ETA57_RS05060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA57_RS05075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA57_RS05080	COG0756	dUTP diphosphatase activity
ETA57_RS05155	COG1793	dna ligase
ETA57_RS05225	COG0740	serine-type endopeptidase activity
ETA57_RS05275	COG3953	SLT domain
ETA57_RS05275	COG5280	Phage tail tape measure protein TP901
ETA57_RS05315	COG5632	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS05315	COG1388	LysM domain
ETA57_RS05315	COG3409	Peptidoglycan-binding domain 1 protein
ETA57_RS05340	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS05365	COG0457	Tetratricopeptide repeat
ETA57_RS05405	COG5444	nuclease activity
ETA57_RS05425	COG0457	Tetratricopeptide repeat
ETA57_RS05430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETA57_RS05440	COG0710	3-dehydroquinate dehydratase activity
ETA57_RS05445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETA57_RS05450	COG1116	anion transmembrane transporter activity
ETA57_RS05455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETA57_RS05460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETA57_RS05465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA57_RS05475	COG1476	TRANSCRIPTIONal
ETA57_RS05485	COG1131	(ABC) transporter
ETA57_RS05505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETA57_RS05520	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETA57_RS05530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETA57_RS05535	COG0789	Transcriptional regulator
ETA57_RS05540	COG1664	Polymer-forming cytoskeletal
ETA57_RS05550	COG2766	serine protein kinase
ETA57_RS05555	COG2718	Belongs to the UPF0229 family
ETA57_RS05560	COG1566	PFAM secretion protein HlyD family protein
ETA57_RS05565	COG2814	Major facilitator Superfamily
ETA57_RS05570	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS05585	COG1131	(ABC) transporter
ETA57_RS05590	COG1131	(ABC) transporter
ETA57_RS05595	COG1131	(ABC) transporter
ETA57_RS05600	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA57_RS05605	COG1278	Cold shock
ETA57_RS05610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETA57_RS05615	COG2011	ABC-type metal ion transport system permease component
ETA57_RS05620	COG1464	Belongs to the NlpA lipoprotein family
ETA57_RS05625	COG1823	symporter activity
ETA57_RS05650	COG5577	PFAM Coat F domain
ETA57_RS05655	COG5002	protein histidine kinase activity
ETA57_RS05665	COG3764	Sortase (surface protein transpeptidase)
ETA57_RS05670	COG0564	pseudouridine synthase activity
ETA57_RS05680	COG0517	IMP dehydrogenase activity
ETA57_RS05685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETA57_RS05690	COG3153	acetyltransferase
ETA57_RS05690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETA57_RS05695	COG0488	(ABC) transporter
ETA57_RS05710	COG0679	Auxin Efflux Carrier
ETA57_RS05715	COG0604	alcohol dehydrogenase
ETA57_RS05720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ETA57_RS05725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETA57_RS05730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETA57_RS05735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETA57_RS05740	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETA57_RS05755	COG4585	Histidine kinase
ETA57_RS05755	COG2203	Gaf domain
ETA57_RS05760	COG2197	response regulator
ETA57_RS05765	COG0431	NADPH-dependent FMN reductase
ETA57_RS05780	COG1959	2 iron, 2 sulfur cluster binding
ETA57_RS05785	COG1017	nitric oxide dioxygenase activity
ETA57_RS05785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ETA57_RS05790	COG2719	SpoVR family
ETA57_RS05795	COG0791	NLP P60 protein
ETA57_RS05795	COG1388	LysM domain
ETA57_RS05800	COG0583	DNA-binding transcription factor activity
ETA57_RS05805	COG0372	Belongs to the citrate synthase family
ETA57_RS05810	COG2133	pyrroloquinoline quinone binding
ETA57_RS05820	COG0733	neurotransmitter:sodium symporter activity
ETA57_RS05830	COG2207	Transcriptional regulator
ETA57_RS05830	COG3708	Transcriptional regulator
ETA57_RS05835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA57_RS05855	COG1595	DNA-templated transcription, initiation
ETA57_RS05860	COG0662	Cupin 2, conserved barrel domain protein
ETA57_RS05870	COG0204	Acyl-transferase
ETA57_RS05875	COG3152	Membrane
ETA57_RS05885	COG1309	transcriptional regulator
ETA57_RS05890	COG1253	flavin adenine dinucleotide binding
ETA57_RS05895	COG0789	Transcriptional regulator
ETA57_RS05900	COG1253	flavin adenine dinucleotide binding
ETA57_RS05920	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETA57_RS05925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ETA57_RS05930	COG0584	glycerophosphoryl diester phosphodiesterase
ETA57_RS05940	COG0668	transmembrane transport
ETA57_RS05945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ETA57_RS05955	COG0726	polysaccharide deacetylase
ETA57_RS05965	COG1757	Na H antiporter
ETA57_RS05970	COG2017	converts alpha-aldose to the beta-anomer
ETA57_RS05995	COG0589	response to stress
ETA57_RS06000	COG1132	(ABC) transporter
ETA57_RS06005	COG1132	(ABC) transporter
ETA57_RS06010	COG0702	epimerase
ETA57_RS06025	COG3842	ATPase activity
ETA57_RS06030	COG2508	Transcriptional regulator
ETA57_RS06040	COG0189	ligase activity
ETA57_RS06045	COG0189	ligase activity
ETA57_RS06050	COG4399	Belongs to the UPF0754 family
ETA57_RS06055	COG3679	Belongs to the UPF0342 family
ETA57_RS06065	COG0561	phosphatase activity
ETA57_RS06070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETA57_RS06075	COG0475	glutathione-regulated potassium exporter activity
ETA57_RS06080	COG0490	domain, Protein
ETA57_RS06090	COG1024	Enoyl-CoA hydratase
ETA57_RS06095	COG0457	Tetratricopeptide repeat
ETA57_RS06110	COG4152	abc transporter atp-binding protein
ETA57_RS06115	COG1668	transmembrane transport
ETA57_RS06120	COG0420	3'-5' exonuclease activity
ETA57_RS06125	COG4717	serine-type aminopeptidase activity
ETA57_RS06130	COG3481	metal-dependent phosphohydrolase, HD sub domain
ETA57_RS06140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETA57_RS06170	COG1846	Transcriptional regulator
ETA57_RS06175	COG4980	gas vesicle protein
ETA57_RS06190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETA57_RS06195	COG0537	adenosine 5'-monophosphoramidase activity
ETA57_RS06200	COG1131	(ABC) transporter
ETA57_RS06205	COG4473	ABC transporter
ETA57_RS06215	COG1473	amidohydrolase
ETA57_RS06220	COG3069	C4-dicarboxylate transmembrane transporter activity
ETA57_RS06225	COG2329	Antibiotic biosynthesis monooxygenase
ETA57_RS06230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA57_RS06235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETA57_RS06240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETA57_RS06245	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ETA57_RS06250	COG1309	transcriptional regulator
ETA57_RS06255	COG1511	domain protein
ETA57_RS06260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA57_RS06275	COG1301	dicarboxylic acid transport
ETA57_RS06285	COG1234	tRNA 3'-trailer cleavage
ETA57_RS06290	COG0095	Lipoate-protein ligase
ETA57_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS06305	COG1396	sequence-specific DNA binding
ETA57_RS06320	COG0501	Belongs to the peptidase M48B family
ETA57_RS06330	COG0697	spore germination
ETA57_RS06335	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ETA57_RS06340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS06345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS06350	COG0406	alpha-ribazole phosphatase activity
ETA57_RS06355	COG0840	transmembrane signaling receptor activity
ETA57_RS06360	COG0723	plastoquinol--plastocyanin reductase activity
ETA57_RS06360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETA57_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS06375	COG4903	ComK protein
ETA57_RS06385	COG0398	Pfam SNARE associated Golgi protein
ETA57_RS06390	COG0681	Belongs to the peptidase S26 family
ETA57_RS06395	COG1404	Belongs to the peptidase S8 family
ETA57_RS06405	COG2508	Transcriptional regulator
ETA57_RS06415	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETA57_RS06420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA57_RS06425	COG3257	ureidoglycine aminohydrolase activity
ETA57_RS06430	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETA57_RS06435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETA57_RS06445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETA57_RS06455	COG0549	Belongs to the carbamate kinase family
ETA57_RS06460	COG2814	Major facilitator Superfamily
ETA57_RS06470	COG0457	Tetratricopeptide repeat
ETA57_RS06490	COG1609	Transcriptional regulator
ETA57_RS06495	COG1653	transport
ETA57_RS06500	COG1175	transmembrane transport
ETA57_RS06505	COG0395	ABC-type sugar transport system, permease component
ETA57_RS06510	COG1486	melibiose metabolic process
ETA57_RS06515	COG3180	Ammonia monooxygenase
ETA57_RS06530	COG3546	catalase activity
ETA57_RS06535	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS06540	COG2814	Major facilitator Superfamily
ETA57_RS06540	COG0477	Major facilitator Superfamily
ETA57_RS06550	COG5002	protein histidine kinase activity
ETA57_RS06555	COG0745	RESPONSE REGULATOR receiver
ETA57_RS06560	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ETA57_RS06565	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETA57_RS06570	COG4149	molybdate abc transporter
ETA57_RS06575	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ETA57_RS06580	COG1074	ATP-dependent DNA helicase activity
ETA57_RS06585	COG0420	3'-5' exonuclease activity
ETA57_RS06590	COG0419	ATPase involved in DNA repair
ETA57_RS06635	COG5337	Spore coat protein CotH
ETA57_RS06665	COG0367	asparagine synthase
ETA57_RS06670	COG0004	ammonium transporteR
ETA57_RS06675	COG0347	Belongs to the P(II) protein family
ETA57_RS06680	COG0534	Mate efflux family protein
ETA57_RS06685	COG1917	Cupin 2, conserved barrel domain protein
ETA57_RS06685	COG2207	Transcriptional regulator
ETA57_RS06695	COG1609	Transcriptional regulator
ETA57_RS06700	COG0673	inositol 2-dehydrogenase activity
ETA57_RS06715	COG0076	glutamate decarboxylase activity
ETA57_RS06740	COG2153	protein acetylation
ETA57_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS06750	COG2378	regulation of single-species biofilm formation
ETA57_RS06760	COG0646	methionine synthase
ETA57_RS06760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETA57_RS06765	COG1666	GTP binding
ETA57_RS06770	COG2996	Protein conserved in bacteria
ETA57_RS06785	COG1307	EDD domain protein, DegV family
ETA57_RS06790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS06800	COG0516	GMP reductase activity
ETA57_RS06810	COG0561	phosphatase activity
ETA57_RS06815	COG1073	alpha beta
ETA57_RS06820	COG2151	metal-sulfur cluster biosynthetic enzyme
ETA57_RS06830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETA57_RS06835	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETA57_RS06840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ETA57_RS06845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETA57_RS06850	COG0505	Belongs to the CarA family
ETA57_RS06855	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETA57_RS06860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETA57_RS06865	COG1968	undecaprenyl-diphosphatase activity
ETA57_RS06880	COG2267	carboxylic ester hydrolase activity
ETA57_RS06890	COG1744	ABC transporter substrate-binding protein PnrA-like
ETA57_RS06905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA57_RS06910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETA57_RS06915	COG5504	Zn-dependent protease
ETA57_RS06920	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS06925	COG4608	Belongs to the ABC transporter superfamily
ETA57_RS06935	COG0601	transmembrane transport
ETA57_RS06940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS06965	COG0180	Tryptophanyl-tRNA synthetase
ETA57_RS06975	COG4166	transmembrane transport
ETA57_RS06980	COG0601	transmembrane transport
ETA57_RS06985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS06990	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS06995	COG4608	Belongs to the ABC transporter superfamily
ETA57_RS07000	COG0456	acetyltransferase
ETA57_RS07005	COG1393	Belongs to the ArsC family
ETA57_RS07010	COG0861	Integral membrane protein TerC family
ETA57_RS07020	COG4862	establishment of competence for transformation
ETA57_RS07040	COG4565	transcriptional regulatory protein
ETA57_RS07045	COG3290	protein histidine kinase activity
ETA57_RS07050	COG4469	Competence protein
ETA57_RS07055	COG1164	Oligoendopeptidase f
ETA57_RS07060	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ETA57_RS07065	COG2346	COG2346, Truncated hemoglobins
ETA57_RS07070	COG0741	lytic transglycosylase activity
ETA57_RS07075	COG4116	CYTH
ETA57_RS07085	COG2357	RelA SpoT domain protein
ETA57_RS07090	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETA57_RS07095	COG0564	pseudouridine synthase activity
ETA57_RS07100	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETA57_RS07110	COG0475	glutathione-regulated potassium exporter activity
ETA57_RS07110	COG0569	domain protein
ETA57_RS07115	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETA57_RS07120	COG0352	thiamine-phosphate diphosphorylase activity
ETA57_RS07130	COG2104	thiamine diphosphate biosynthetic process
ETA57_RS07135	COG2022	thiamine diphosphate biosynthetic process
ETA57_RS07140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETA57_RS07145	COG0351	phosphomethylpyrimidine kinase
ETA57_RS07150	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETA57_RS07205	COG0210	DNA helicase
ETA57_RS07215	COG0586	Pfam SNARE associated Golgi protein
ETA57_RS07220	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETA57_RS07225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETA57_RS07230	COG2246	polysaccharide biosynthetic process
ETA57_RS07235	COG2153	protein acetylation
ETA57_RS07240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETA57_RS07245	COG2382	esterase
ETA57_RS07265	COG0626	cystathionine gamma-synthase activity
ETA57_RS07270	COG0626	cystathionine gamma-synthase activity
ETA57_RS07275	COG5505	Protein of unknown function (DUF819)
ETA57_RS07295	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA57_RS07315	COG0110	maltose O-acetyltransferase activity
ETA57_RS07325	COG0583	DNA-binding transcription factor activity
ETA57_RS07330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETA57_RS07335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETA57_RS07340	COG0583	DNA-binding transcription factor activity
ETA57_RS07345	COG0697	spore germination
ETA57_RS07350	COG0346	lactoylglutathione lyase activity
ETA57_RS07360	COG3584	3D domain protein
ETA57_RS07360	COG1388	LysM domain
ETA57_RS07365	COG2814	Major facilitator Superfamily
ETA57_RS07370	COG1309	transcriptional regulator
ETA57_RS07395	COG4195	phage-related replication protein
ETA57_RS07400	COG2856	Zn peptidase
ETA57_RS07405	COG1396	sequence-specific DNA binding
ETA57_RS07420	COG1522	sequence-specific DNA binding
ETA57_RS07425	COG1484	DNA-dependent DNA replication
ETA57_RS07440	COG1595	DNA-templated transcription, initiation
ETA57_RS07445	COG5484	DNA packaging
ETA57_RS07445	COG3728	DNA packaging
ETA57_RS07450	COG1783	phage Terminase large subunit
ETA57_RS07455	COG5518	Phage portal protein
ETA57_RS07460	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ETA57_RS07465	COG4653	Phage capsid family
ETA57_RS07515	COG3953	SLT domain
ETA57_RS07515	COG5412	phage tail tape measure protein
ETA57_RS07520	COG1652	LysM domain
ETA57_RS07525	COG4193	domain, Protein
ETA57_RS07535	COG3628	GPW Gp25 family protein
ETA57_RS07545	COG3778	Protein conserved in bacteria
ETA57_RS07580	COG1802	Transcriptional regulator
ETA57_RS07585	COG1063	alcohol dehydrogenase
ETA57_RS07590	COG1312	Catalyzes the dehydration of D-mannonate
ETA57_RS07595	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS07600	COG1063	alcohol dehydrogenase
ETA57_RS07605	COG2271	Major facilitator Superfamily
ETA57_RS07620	COG0306	phosphate transporter
ETA57_RS07625	COG1392	Phosphate transport regulator
ETA57_RS07630	COG0405	Gamma-glutamyltransferase
ETA57_RS07635	COG5578	integral membrane protein
ETA57_RS07645	COG4753	response regulator
ETA57_RS07645	COG2207	Transcriptional regulator
ETA57_RS07650	COG1653	transport
ETA57_RS07655	COG1175	transmembrane transport
ETA57_RS07665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETA57_RS07690	COG2755	lipolytic protein G-D-S-L family
ETA57_RS07695	COG3401	FG-GAP repeat protein
ETA57_RS07700	COG0667	Aldo Keto reductase
ETA57_RS07705	COG2755	lipolytic protein G-D-S-L family
ETA57_RS07710	COG1874	Beta-galactosidase
ETA57_RS07720	COG1653	transport
ETA57_RS07725	COG4209	transmembrane transport
ETA57_RS07730	COG0395	ABC-type sugar transport system, permease component
ETA57_RS07735	COG0531	amino acid
ETA57_RS07740	COG0346	lactoylglutathione lyase activity
ETA57_RS07755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA57_RS07760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA57_RS07765	COG2362	D-Aminopeptidase
ETA57_RS07770	COG0601	transmembrane transport
ETA57_RS07775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS07780	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS07785	COG4166	transmembrane transport
ETA57_RS07790	COG1619	proteins homologs of microcin C7 resistance protein MccF
ETA57_RS07795	COG4948	Mandelate Racemase Muconate Lactonizing
ETA57_RS07800	COG0791	NLP P60 protein
ETA57_RS07805	COG4608	Belongs to the ABC transporter superfamily
ETA57_RS07810	COG1834	amidinotransferase
ETA57_RS07815	COG1607	acyl-coa hydrolase
ETA57_RS07820	COG2323	membrane
ETA57_RS07825	COG3866	Pectate lyase
ETA57_RS07845	COG2318	DinB family
ETA57_RS07850	COG2076	Multidrug Resistance protein
ETA57_RS07855	COG2076	Multidrug Resistance protein
ETA57_RS07860	COG0788	formyltetrahydrofolate deformylase activity
ETA57_RS07865	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETA57_RS07870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETA57_RS07875	COG1764	response to oxidative stress
ETA57_RS07880	COG1846	Transcriptional regulator
ETA57_RS07885	COG1764	response to oxidative stress
ETA57_RS07900	COG0590	tRNA wobble adenosine to inosine editing
ETA57_RS07905	COG0406	alpha-ribazole phosphatase activity
ETA57_RS07920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETA57_RS07925	COG1404	Belongs to the peptidase S8 family
ETA57_RS07935	COG2239	Acts as a magnesium transporter
ETA57_RS07945	COG0582	viral genome integration into host DNA
ETA57_RS07950	COG2856	Zn peptidase
ETA57_RS07970	COG3620	sequence-specific DNA binding
ETA57_RS07990	COG3617	BRO family, N-terminal domain
ETA57_RS08005	COG5377	YqaJ viral recombinase family
ETA57_RS08010	COG3723	Recombinational DNA repair protein, rece pathway
ETA57_RS08015	COG3935	DnaD domain protein
ETA57_RS08020	COG1484	DNA-dependent DNA replication
ETA57_RS08050	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ETA57_RS08060	COG0629	single-stranded DNA binding
ETA57_RS08105	COG5484	DNA packaging
ETA57_RS08110	COG1783	phage Terminase large subunit
ETA57_RS08215	COG4824	toxin secretion phage lysis holin
ETA57_RS08230	COG5444	nuclease activity
ETA57_RS08255	COG0789	Transcriptional regulator
ETA57_RS08270	COG1846	Transcriptional regulator
ETA57_RS08275	COG3285	dna ligase
ETA57_RS08275	COG1793	dna ligase
ETA57_RS08280	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ETA57_RS08285	COG3300	MHYT domain
ETA57_RS08285	COG5001	Diguanylate cyclase
ETA57_RS08290	COG0586	Pfam SNARE associated Golgi protein
ETA57_RS08295	COG0861	Integral membrane protein TerC family
ETA57_RS08300	COG1191	sigma factor activity
ETA57_RS08320	COG0501	Belongs to the peptidase M48B family
ETA57_RS08325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETA57_RS08330	COG0768	penicillin binding
ETA57_RS08345	COG3594	Acyltransferase
ETA57_RS08350	COG5002	protein histidine kinase activity
ETA57_RS08355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETA57_RS08360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETA57_RS08365	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ETA57_RS08370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETA57_RS08375	COG0436	Aminotransferase
ETA57_RS08380	COG1850	ribulose-bisphosphate carboxylase activity
ETA57_RS08385	COG0235	Class ii aldolase
ETA57_RS08385	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ETA57_RS08390	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETA57_RS08395	COG0346	lactoylglutathione lyase activity
ETA57_RS08400	COG3339	Conserved Protein
ETA57_RS08410	COG3852	Histidine kinase
ETA57_RS08415	COG1846	Transcriptional regulator
ETA57_RS08420	COG1360	Flagellar Motor Protein
ETA57_RS08425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETA57_RS08430	COG0542	response to heat
ETA57_RS08435	COG3949	Membrane
ETA57_RS08440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ETA57_RS08445	COG0720	synthase
ETA57_RS08450	COG0602	queuosine metabolic process
ETA57_RS08455	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETA57_RS08465	COG3739	integral membrane protein
ETA57_RS08470	COG3655	Transcriptional regulator
ETA57_RS08500	COG4873	Protein conserved in bacteria
ETA57_RS08510	COG3773	Cell wall hydrolase
ETA57_RS08515	COG2244	polysaccharide biosynthetic process
ETA57_RS08520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS08525	COG2217	Heavy metal translocating P-type atpase
ETA57_RS08530	COG0006	proline dipeptidase activity
ETA57_RS08540	COG1609	Transcriptional regulator
ETA57_RS08545	COG3711	transcriptional antiterminator
ETA57_RS08550	COG2190	(PTS) system
ETA57_RS08550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS08550	COG1263	PTS System
ETA57_RS08555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS08560	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETA57_RS08570	COG1533	DNA photolyase activity
ETA57_RS08575	COG0456	acetyltransferase
ETA57_RS08580	COG0840	transmembrane signaling receptor activity
ETA57_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS08590	COG2084	Dehydrogenase
ETA57_RS08595	COG2340	Cysteine-rich secretory protein family
ETA57_RS08600	COG0768	penicillin binding
ETA57_RS08605	COG4191	Histidine kinase
ETA57_RS08610	COG0436	Aminotransferase
ETA57_RS08615	COG1714	RDD family
ETA57_RS08625	COG0835	chemotaxis
ETA57_RS08625	COG0784	Response regulator, receiver
ETA57_RS08635	COG2814	Major facilitator Superfamily
ETA57_RS08640	COG1376	ErfK ybiS ycfS ynhG family protein
ETA57_RS08650	COG1408	metallophosphoesterase
ETA57_RS08655	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS08660	COG2200	EAL domain
ETA57_RS08670	COG4703	Protein of unknown function (DUF1797)
ETA57_RS08675	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ETA57_RS08685	COG0517	IMP dehydrogenase activity
ETA57_RS08690	COG0583	DNA-binding transcription factor activity
ETA57_RS08695	COG0716	FMN binding
ETA57_RS08705	COG0716	FMN binding
ETA57_RS08710	COG2171	N-acyltransferase activity
ETA57_RS08715	COG1473	amidohydrolase
ETA57_RS08725	COG0450	alkyl hydroperoxide reductase
ETA57_RS08730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS08745	COG0746	molybdenum cofactor guanylyltransferase activity
ETA57_RS08750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETA57_RS08755	COG0303	'Molybdopterin
ETA57_RS08760	COG1763	Mo-molybdopterin cofactor biosynthetic process
ETA57_RS08765	COG0314	molybdopterin synthase activity
ETA57_RS08770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ETA57_RS08780	COG1132	(ABC) transporter
ETA57_RS08785	COG1132	(ABC) transporter
ETA57_RS08795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETA57_RS08800	COG1136	(ABC) transporter
ETA57_RS08805	COG0577	efflux transmembrane transporter activity
ETA57_RS08810	COG1349	DNA-binding transcription factor activity
ETA57_RS08815	COG1105	Belongs to the carbohydrate kinase PfkB family
ETA57_RS08820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS08820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS08820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS08840	COG0488	(ABC) transporter
ETA57_RS08855	COG2309	aminopeptidase activity
ETA57_RS08865	COG1077	Cell shape determining protein MreB Mrl
ETA57_RS08870	COG2002	toxin-antitoxin pair type II binding
ETA57_RS08875	COG3852	Histidine kinase
ETA57_RS08880	COG0569	domain protein
ETA57_RS08885	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETA57_RS08890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETA57_RS08895	COG5503	Protein of unknown function (DUF1447)
ETA57_RS08900	COG0561	phosphatase activity
ETA57_RS08905	COG0242	peptide deformylase activity
ETA57_RS08915	COG0497	DNA recombination
ETA57_RS08920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA57_RS08925	COG0022	dehydrogenase e1 component
ETA57_RS08930	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA57_RS08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA57_RS08940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS08950	COG1982	Orn Lys Arg decarboxylase major
ETA57_RS08960	COG4476	Belongs to the UPF0223 family
ETA57_RS08965	COG4493	Belongs to the UPF0637 family
ETA57_RS08975	COG0483	inositol monophosphate 1-phosphatase activity
ETA57_RS08995	COG1595	DNA-templated transcription, initiation
ETA57_RS09010	COG1217	gtp-binding protein TYPA
ETA57_RS09025	COG1846	Transcriptional regulator
ETA57_RS09030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ETA57_RS09035	COG4896	Protein conserved in bacteria
ETA57_RS09045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETA57_RS09050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETA57_RS09055	COG2066	Belongs to the glutaminase family
ETA57_RS09060	COG4838	Belongs to the UPF0358 family
ETA57_RS09065	COG0772	Belongs to the SEDS family
ETA57_RS09070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETA57_RS09075	COG1612	heme a metabolic process
ETA57_RS09080	COG0109	protoheme IX farnesyltransferase activity
ETA57_RS09085	COG2010	Cytochrome c
ETA57_RS09085	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETA57_RS09090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETA57_RS09095	COG1845	cytochrome c oxidase, subunit III
ETA57_RS09100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETA57_RS09105	COG3336	cytochrome c oxidase
ETA57_RS09115	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETA57_RS09120	COG2340	Cysteine-rich secretory protein family
ETA57_RS09135	COG3679	Belongs to the UPF0342 family
ETA57_RS09140	COG4471	UPF0298 protein
ETA57_RS09145	COG0742	ribosomal rna small subunit methyltransferase
ETA57_RS09150	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETA57_RS09155	COG3314	Sporulation integral membrane protein YlbJ
ETA57_RS09160	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETA57_RS09165	COG1323	Belongs to the UPF0348 family
ETA57_RS09170	COG1399	metal-binding, possibly nucleic acid-binding protein
ETA57_RS09175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETA57_RS09185	COG0454	-acetyltransferase
ETA57_RS09190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ETA57_RS09195	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ETA57_RS09200	COG2001	Belongs to the MraZ family
ETA57_RS09205	COG0275	rRNA processing
ETA57_RS09210	COG4839	cell division protein FtsL
ETA57_RS09215	COG0768	penicillin binding
ETA57_RS09220	COG0768	penicillin binding
ETA57_RS09230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETA57_RS09235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETA57_RS09240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETA57_RS09245	COG0772	Belongs to the SEDS family
ETA57_RS09250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA57_RS09255	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETA57_RS09260	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ETA57_RS09265	COG3879	Bacterial protein of unknown function (DUF881)
ETA57_RS09270	COG3879	Bacterial protein of unknown function (DUF881)
ETA57_RS09275	COG3856	small basic protein
ETA57_RS09280	COG0849	cell division
ETA57_RS09285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ETA57_RS09295	COG1404	Belongs to the peptidase S8 family
ETA57_RS09295	COG4412	M6 family metalloprotease domain protein
ETA57_RS09300	COG1404	Belongs to the peptidase S8 family
ETA57_RS09300	COG4412	M6 family metalloprotease domain protein
ETA57_RS09310	COG1191	sigma factor activity
ETA57_RS09315	COG1191	sigma factor activity
ETA57_RS09320	COG1119	ATPase activity
ETA57_RS09325	COG0500	methyltransferase
ETA57_RS09330	COG1873	PFAM PRC-barrel domain
ETA57_RS09335	COG1496	oxidoreductase activity
ETA57_RS09340	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETA57_RS09345	COG1799	cell septum assembly
ETA57_RS09350	COG0762	integral membrane protein
ETA57_RS09355	COG2302	S4 RNA-binding domain
ETA57_RS09360	COG3599	regulation of cell shape
ETA57_RS09365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETA57_RS09370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA57_RS09375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETA57_RS09380	COG0564	pseudouridine synthase activity
ETA57_RS09385	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ETA57_RS09390	COG2233	PERMEase
ETA57_RS09395	COG0540	Belongs to the ATCase OTCase family
ETA57_RS09400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETA57_RS09405	COG0505	Belongs to the CarA family
ETA57_RS09410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETA57_RS09415	COG0543	2 iron, 2 sulfur cluster binding
ETA57_RS09420	COG0167	dihydroorotate dehydrogenase activity
ETA57_RS09425	COG0284	orotidine-5'-phosphate decarboxylase activity
ETA57_RS09430	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETA57_RS09440	COG0175	sulfate reduction
ETA57_RS09445	COG0306	phosphate transporter
ETA57_RS09450	COG2046	Belongs to the sulfate adenylyltransferase family
ETA57_RS09455	COG0529	Catalyzes the synthesis of activated sulfate
ETA57_RS09460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ETA57_RS09465	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
ETA57_RS09470	COG1648	precorrin-2 dehydrogenase activity
ETA57_RS09480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETA57_RS09485	COG1561	YicC-like family, N-terminal region
ETA57_RS09490	COG2052	Domain of unknown function (DUF370)
ETA57_RS09495	COG0194	GDP metabolic process
ETA57_RS09500	COG1758	RNA polymerase activity
ETA57_RS09505	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETA57_RS09510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETA57_RS09515	COG0242	peptide deformylase activity
ETA57_RS09520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETA57_RS09525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETA57_RS09525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETA57_RS09530	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETA57_RS09535	COG0631	protein serine/threonine phosphatase activity
ETA57_RS09540	COG2815	serine threonine protein kinase
ETA57_RS09540	COG0515	serine threonine protein kinase
ETA57_RS09545	COG1162	GTPase activity
ETA57_RS09550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETA57_RS09555	COG1564	THIamine pyrophosphokinase
ETA57_RS09565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETA57_RS09570	COG1302	Protein conserved in bacteria
ETA57_RS09575	COG1461	Dihydroxyacetone kinase
ETA57_RS09580	COG1760	l-serine dehydratase
ETA57_RS09585	COG1760	l-serine dehydratase
ETA57_RS09590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETA57_RS09595	COG1349	DNA-binding transcription factor activity
ETA57_RS09600	COG0416	fatty acid biosynthetic process
ETA57_RS09605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETA57_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS09615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA57_RS09620	COG0571	ribonuclease III activity
ETA57_RS09625	COG1196	nuclear chromosome segregation
ETA57_RS09630	COG0552	protein localization to endoplasmic reticulum
ETA57_RS09635	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ETA57_RS09640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETA57_RS09645	COG0228	four-way junction DNA binding
ETA57_RS09650	COG1837	Belongs to the UPF0109 family
ETA57_RS09660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ETA57_RS09665	COG0336	Belongs to the RNA methyltransferase TrmD family
ETA57_RS09670	COG0335	large ribosomal subunit rRNA binding
ETA57_RS09675	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETA57_RS09680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETA57_RS09690	COG2257	FlhB HrpN YscU SpaS Family
ETA57_RS09695	COG0045	succinate-CoA ligase (ADP-forming) activity
ETA57_RS09700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ETA57_RS09705	COG0758	DNA mediated transformation
ETA57_RS09710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETA57_RS09715	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ETA57_RS09720	COG4974	Belongs to the 'phage' integrase family
ETA57_RS09725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ETA57_RS09730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ETA57_RS09735	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETA57_RS09740	COG1815	bacterial-type flagellum-dependent cell motility
ETA57_RS09745	COG1558	bacterial-type flagellum-dependent cell motility
ETA57_RS09750	COG1677	Flagellar hook-basal body complex protein FliE
ETA57_RS09755	COG1766	The M ring may be actively involved in energy transduction
ETA57_RS09760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA57_RS09765	COG1317	bacterial-type flagellum organization
ETA57_RS09770	COG1157	protein secretion by the type III secretion system
ETA57_RS09775	COG2882	bacterial-type flagellum organization
ETA57_RS09785	COG3144	bacterial-type flagellum assembly
ETA57_RS09790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETA57_RS09795	COG4786	Flagellar basal body rod
ETA57_RS09800	COG1582	Flagellar protein (FlbD)
ETA57_RS09805	COG1580	Controls the rotational direction of flagella during chemotaxis
ETA57_RS09810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA57_RS09815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETA57_RS09815	COG1776	CheC inhibitor of MCP methylation
ETA57_RS09820	COG2201	protein-glutamate methylesterase activity
ETA57_RS09825	COG3190	flagellar
ETA57_RS09830	COG1338	Plays a role in the flagellum-specific transport system
ETA57_RS09835	COG1987	bacterial-type flagellum assembly
ETA57_RS09840	COG1684	flagellar biosynthetic protein fliR
ETA57_RS09845	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETA57_RS09850	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETA57_RS09855	COG1419	protein localization to endoplasmic reticulum
ETA57_RS09860	COG0455	bacterial-type flagellum organization
ETA57_RS09865	COG2201	protein-glutamate methylesterase activity
ETA57_RS09870	COG2198	Histidine kinase
ETA57_RS09870	COG0643	Histidine kinase
ETA57_RS09875	COG0835	chemotaxis
ETA57_RS09880	COG1776	CheC inhibitor of MCP methylation
ETA57_RS09885	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETA57_RS09890	COG1191	sigma factor activity
ETA57_RS09900	COG0052	Belongs to the universal ribosomal protein uS2 family
ETA57_RS09905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETA57_RS09910	COG0528	UMP kinase activity
ETA57_RS09915	COG0233	cytoplasmic translational termination
ETA57_RS09920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETA57_RS09925	COG4589	Belongs to the CDS family
ETA57_RS09930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETA57_RS09935	COG0750	zinc metalloprotease
ETA57_RS09940	COG0442	prolyl-tRNA aminoacylation
ETA57_RS09945	COG2176	DNA-directed DNA polymerase activity
ETA57_RS09975	COG0779	Required for maturation of 30S ribosomal subunits
ETA57_RS09980	COG0195	Participates in both transcription termination and antitermination
ETA57_RS09985	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETA57_RS09990	COG1358	cellular component organization or biogenesis
ETA57_RS09995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETA57_RS10000	COG1550	Protein conserved in bacteria
ETA57_RS10005	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETA57_RS10010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETA57_RS10015	COG0196	riboflavin kinase activity
ETA57_RS10020	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETA57_RS10025	COG1185	polyribonucleotide nucleotidyltransferase activity
ETA57_RS10030	COG0726	polysaccharide deacetylase
ETA57_RS10035	COG0612	Peptidase, M16
ETA57_RS10040	COG1873	PFAM PRC-barrel domain
ETA57_RS10045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETA57_RS10050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETA57_RS10055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ETA57_RS10060	COG0527	aspartate kinase activity
ETA57_RS10070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ETA57_RS10075	COG0740	serine-type endopeptidase activity
ETA57_RS10085	COG1674	ftsk spoiiie
ETA57_RS10085	COG4980	gas vesicle protein
ETA57_RS10090	COG2188	Transcriptional regulator
ETA57_RS10095	COG2814	Major facilitator Superfamily
ETA57_RS10100	COG0612	Peptidase, M16
ETA57_RS10105	COG0612	Peptidase, M16
ETA57_RS10110	COG0300	oxidoreductase activity
ETA57_RS10125	COG1426	Protein conserved in bacteria
ETA57_RS10130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETA57_RS10135	COG1546	Belongs to the CinA family
ETA57_RS10135	COG1058	Belongs to the CinA family
ETA57_RS10145	COG1418	mRNA catabolic process
ETA57_RS10150	COG1692	metallophosphoesterase
ETA57_RS10155	COG2359	stage V sporulation protein S
ETA57_RS10165	COG1063	alcohol dehydrogenase
ETA57_RS10170	COG0156	8-amino-7-oxononanoate synthase activity
ETA57_RS10175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETA57_RS10180	COG4550	Control of competence regulator ComK, YlbF/YmcA
ETA57_RS10190	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETA57_RS10195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ETA57_RS10200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETA57_RS10205	COG5444	nuclease activity
ETA57_RS10225	COG0523	cobalamin synthesis protein
ETA57_RS10235	COG1247	-acetyltransferase
ETA57_RS10250	COG1231	oxidoreductase activity
ETA57_RS10255	COG3619	membrane
ETA57_RS10260	COG3263	regulation of cellular component size
ETA57_RS10265	COG2814	Major facilitator Superfamily
ETA57_RS10270	COG2267	carboxylic ester hydrolase activity
ETA57_RS10280	COG0393	Putative heavy-metal-binding
ETA57_RS10285	COG0398	Pfam SNARE associated Golgi protein
ETA57_RS10290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETA57_RS10295	COG1819	glycosyl
ETA57_RS10300	COG0531	amino acid
ETA57_RS10305	COG5577	PFAM Coat F domain
ETA57_RS10315	COG1388	LysM domain
ETA57_RS10315	COG3858	chitin binding
ETA57_RS10320	COG1309	transcriptional regulator
ETA57_RS10325	COG3631	Ketosteroid isomerase-related protein
ETA57_RS10330	COG0702	epimerase
ETA57_RS10340	COG1764	response to oxidative stress
ETA57_RS10345	COG2076	Multidrug Resistance protein
ETA57_RS10350	COG2076	Multidrug Resistance protein
ETA57_RS10365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETA57_RS10370	COG1923	regulation of RNA biosynthetic process
ETA57_RS10385	COG1780	Probably involved in ribonucleotide reductase function
ETA57_RS10390	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA57_RS10395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETA57_RS10400	COG4112	unkown
ETA57_RS10420	COG1802	Transcriptional regulator
ETA57_RS10425	COG0697	spore germination
ETA57_RS10465	COG1309	transcriptional regulator
ETA57_RS10515	COG0464	growth
ETA57_RS10520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETA57_RS10525	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ETA57_RS10530	COG0789	Transcriptional regulator
ETA57_RS10535	COG0174	glutamine synthetase
ETA57_RS10595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA57_RS10595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA57_RS10645	COG4626	Terminase
ETA57_RS10645	COG1802	Transcriptional regulator
ETA57_RS10705	COG5280	Phage tail tape measure protein TP901
ETA57_RS10705	COG3953	SLT domain
ETA57_RS10715	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETA57_RS10720	COG5434	Belongs to the glycosyl hydrolase 28 family
ETA57_RS10760	COG5444	nuclease activity
ETA57_RS10815	COG1073	alpha beta
ETA57_RS10855	COG1309	transcriptional regulator
ETA57_RS10860	COG2076	Multidrug Resistance protein
ETA57_RS10865	COG2076	Multidrug Resistance protein
ETA57_RS10890	COG3546	catalase activity
ETA57_RS10915	COG1846	Transcriptional regulator
ETA57_RS10920	COG0778	Nitroreductase
ETA57_RS10925	COG0346	lactoylglutathione lyase activity
ETA57_RS10930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETA57_RS10935	COG0655	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS10955	COG3209	COG3209 Rhs family protein
ETA57_RS10960	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETA57_RS10965	COG1388	LysM domain
ETA57_RS10970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETA57_RS10975	COG4224	UPF0291 protein
ETA57_RS10980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ETA57_RS10990	COG3763	UPF0154 protein
ETA57_RS11000	COG0785	Cytochrome C biogenesis protein
ETA57_RS11005	COG2201	protein-glutamate methylesterase activity
ETA57_RS11010	COG4846	Membrane protein involved in cytochrome C biogenesis
ETA57_RS11020	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA57_RS11035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETA57_RS11040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS11060	COG0824	Thioesterase
ETA57_RS11085	COG4841	protein insertion into membrane
ETA57_RS11090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ETA57_RS11095	COG1832	CoA-binding protein
ETA57_RS11100	COG0187	DNA topoisomerase II activity
ETA57_RS11105	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ETA57_RS11110	COG1609	Transcriptional regulator
ETA57_RS11125	COG2160	L-arabinose isomerase activity
ETA57_RS11145	COG1115	amino acid carrier protein
ETA57_RS11155	COG2181	nitrate reductase activity
ETA57_RS11160	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ETA57_RS11165	COG1140	nitrate reductase beta subunit
ETA57_RS11170	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ETA57_RS11185	COG0535	radical SAM domain protein
ETA57_RS11190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETA57_RS11200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETA57_RS11205	COG2223	nitrite transmembrane transporter activity
ETA57_RS11225	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ETA57_RS11235	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETA57_RS11245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA57_RS11255	COG0492	ferredoxin-NADP+ reductase activity
ETA57_RS11270	COG3420	alginic acid biosynthetic process
ETA57_RS11275	COG1114	Component of the transport system for branched-chain amino acids
ETA57_RS11280	COG1064	alcohol dehydrogenase
ETA57_RS11285	COG0789	Transcriptional regulator
ETA57_RS11310	COG1024	Enoyl-CoA hydratase
ETA57_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS11320	COG2084	Dehydrogenase
ETA57_RS11325	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS11330	COG1482	cell wall glycoprotein biosynthetic process
ETA57_RS11335	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS11335	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS11335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS11360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS11360	COG3711	transcriptional antiterminator
ETA57_RS11375	COG1725	Transcriptional regulator
ETA57_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS11385	COG1312	Catalyzes the dehydration of D-mannonate
ETA57_RS11400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ETA57_RS11410	COG1609	Transcriptional regulator
ETA57_RS11415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA57_RS11420	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ETA57_RS11425	COG0640	Transcriptional regulator
ETA57_RS11435	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ETA57_RS11450	COG1649	PFAM Uncharacterised BCR, COG1649
ETA57_RS11460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETA57_RS11470	COG2027	D-alanyl-D-alanine carboxypeptidase
ETA57_RS11475	COG1252	NADH dehydrogenase
ETA57_RS11490	COG0166	Belongs to the GPI family
ETA57_RS11500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETA57_RS11505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETA57_RS11510	COG1024	Enoyl-CoA hydratase
ETA57_RS11515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETA57_RS11520	COG0511	ligase activity, forming carbon-carbon bonds
ETA57_RS11525	COG0439	Biotin carboxylase
ETA57_RS11530	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS11535	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS11540	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS11545	COG1733	regulation of RNA biosynthetic process
ETA57_RS11550	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETA57_RS11555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETA57_RS11565	COG2323	membrane
ETA57_RS11580	COG0175	sulfate reduction
ETA57_RS11585	COG1809	phosphosulfolactate synthase activity
ETA57_RS11590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS11595	COG4948	Mandelate Racemase Muconate Lactonizing
ETA57_RS11600	COG2814	Major facilitator Superfamily
ETA57_RS11605	COG0463	Glycosyl transferase, family 2
ETA57_RS11620	COG0493	'glutamate synthase
ETA57_RS11625	COG0070	glutamate synthase
ETA57_RS11625	COG0069	glutamate synthase activity
ETA57_RS11625	COG0067	glutamate synthase
ETA57_RS11630	COG0583	DNA-binding transcription factor activity
ETA57_RS11650	COG1846	Transcriptional regulator
ETA57_RS11660	COG1132	(ABC) transporter
ETA57_RS11670	COG0300	oxidoreductase activity
ETA57_RS11675	COG3848	Pyruvate phosphate dikinase
ETA57_RS11675	COG0574	Belongs to the PEP-utilizing enzyme family
ETA57_RS11685	COG0477	Major facilitator Superfamily
ETA57_RS11690	COG0243	molybdopterin cofactor binding
ETA57_RS11695	COG1846	Transcriptional regulator
ETA57_RS11700	COG2814	Major facilitator Superfamily
ETA57_RS11705	COG0531	amino acid
ETA57_RS11715	COG0531	amino acid
ETA57_RS11720	COG0531	amino acid
ETA57_RS11725	COG0697	spore germination
ETA57_RS11730	COG0488	(ABC) transporter
ETA57_RS11735	COG0840	transmembrane signaling receptor activity
ETA57_RS11740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA57_RS11745	COG1404	Belongs to the peptidase S8 family
ETA57_RS11755	COG1309	transcriptional regulator
ETA57_RS11760	COG1846	Transcriptional regulator
ETA57_RS11785	COG1309	transcriptional regulator
ETA57_RS11790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS11795	COG3708	Transcriptional regulator
ETA57_RS11805	COG2378	regulation of single-species biofilm formation
ETA57_RS11815	COG0640	Transcriptional regulator
ETA57_RS11830	COG0531	amino acid
ETA57_RS11835	COG0741	lytic transglycosylase activity
ETA57_RS11840	COG1086	Polysaccharide biosynthesis protein
ETA57_RS11865	COG2322	membrane
ETA57_RS11880	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA57_RS11885	COG1388	LysM domain
ETA57_RS11885	COG3584	3D domain protein
ETA57_RS11890	COG0514	ATP-dependent DNA helicase (RecQ)
ETA57_RS11910	COG2315	Protein conserved in bacteria
ETA57_RS11930	COG2427	Protein of unknown function (DUF1641)
ETA57_RS11965	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
ETA57_RS12005	COG0402	S-adenosylhomocysteine deaminase activity
ETA57_RS12020	COG2267	carboxylic ester hydrolase activity
ETA57_RS12035	COG1280	lysine exporter protein (LysE YggA)
ETA57_RS12040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETA57_RS12050	COG3848	Pyruvate phosphate dikinase
ETA57_RS12050	COG0574	Belongs to the PEP-utilizing enzyme family
ETA57_RS12055	COG1309	transcriptional regulator
ETA57_RS12070	COG2318	DinB family
ETA57_RS12075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETA57_RS12080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA57_RS12095	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS12100	COG2814	Major facilitator Superfamily
ETA57_RS12115	COG1657	PFAM Prenyltransferase squalene oxidase
ETA57_RS12130	COG0733	neurotransmitter:sodium symporter activity
ETA57_RS12135	COG0385	Bile acid
ETA57_RS12140	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA57_RS12145	COG0567	Dehydrogenase, E1 component
ETA57_RS12150	COG4548	von Willebrand factor, type A
ETA57_RS12155	COG0714	Associated with various cellular activities
ETA57_RS12160	COG2032	superoxide dismutase activity
ETA57_RS12165	COG0791	NLP P60 protein
ETA57_RS12165	COG1388	LysM domain
ETA57_RS12175	COG0534	Mate efflux family protein
ETA57_RS12180	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA57_RS12185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA57_RS12195	COG2962	Rard protein
ETA57_RS12205	COG4305	rare lipoprotein A
ETA57_RS12215	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS12220	COG1733	regulation of RNA biosynthetic process
ETA57_RS12225	COG0778	Nitroreductase
ETA57_RS12230	COG0400	carboxylic ester hydrolase activity
ETA57_RS12240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA57_RS12250	COG3409	Peptidoglycan-binding domain 1 protein
ETA57_RS12250	COG0793	Belongs to the peptidase S41A family
ETA57_RS12255	COG2226	methyltransferase
ETA57_RS12270	COG0813	purine-nucleoside phosphorylase activity
ETA57_RS12275	COG0701	Predicted permease
ETA57_RS12295	COG0671	phosphoesterase, PA-phosphatase related
ETA57_RS12310	COG4479	Belongs to the UPF0346 family
ETA57_RS12320	COG1509	lysine 2,3-aminomutase activity
ETA57_RS12325	COG0456	acetyltransferase
ETA57_RS12330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA57_RS12335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ETA57_RS12340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETA57_RS12345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETA57_RS12360	COG0456	acetyltransferase
ETA57_RS12365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETA57_RS12370	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETA57_RS12375	COG1846	Transcriptional regulator
ETA57_RS12385	COG3706	GGDEF domain
ETA57_RS12405	COG4698	Protein conserved in bacteria
ETA57_RS12410	COG2755	lipolytic protein G-D-S-L family
ETA57_RS12415	COG1999	signal sequence binding
ETA57_RS12430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETA57_RS12435	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETA57_RS12440	COG1272	protein, Hemolysin III
ETA57_RS12445	COG0204	Acyl-transferase
ETA57_RS12450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETA57_RS12455	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETA57_RS12470	COG2136	Putative SAM-dependent methyltransferase
ETA57_RS12470	COG2521	methyltransferase
ETA57_RS12480	COG0129	dihydroxy-acid dehydratase activity
ETA57_RS12485	COG1413	lyase activity
ETA57_RS12490	COG1418	mRNA catabolic process
ETA57_RS12495	COG0386	Belongs to the glutathione peroxidase family
ETA57_RS12500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ETA57_RS12505	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ETA57_RS12510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA57_RS12520	COG1278	Cold shock
ETA57_RS12540	COG0328	RNA-DNA hybrid ribonuclease activity
ETA57_RS12545	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ETA57_RS12550	COG0328	RNA-DNA hybrid ribonuclease activity
ETA57_RS12560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA57_RS12570	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETA57_RS12580	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETA57_RS12585	COG3424	synthase
ETA57_RS12590	COG0456	acetyltransferase
ETA57_RS12595	COG2233	PERMEase
ETA57_RS12600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA57_RS12605	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ETA57_RS12610	COG1199	ATP-dependent helicase activity
ETA57_RS12620	COG0116	Belongs to the methyltransferase superfamily
ETA57_RS12630	COG3599	regulation of cell shape
ETA57_RS12635	COG4474	Belongs to the UPF0398 family
ETA57_RS12645	COG3359	exonuclease
ETA57_RS12650	COG1111	helicase
ETA57_RS12650	COG1205	dead DEAH box helicase
ETA57_RS12655	COG2190	(PTS) system
ETA57_RS12660	COG0071	Belongs to the small heat shock protein (HSP20) family
ETA57_RS12695	COG3331	DNA recombination
ETA57_RS12700	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETA57_RS12700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA57_RS12710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETA57_RS12715	COG3935	DnaD domain protein
ETA57_RS12720	COG0017	Asparaginyl-tRNA synthetase
ETA57_RS12725	COG0436	Aminotransferase
ETA57_RS12730	COG5353	protein conserved in bacteria
ETA57_RS12740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETA57_RS12740	COG1199	ATP-dependent helicase activity
ETA57_RS12745	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ETA57_RS12750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETA57_RS12755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETA57_RS12770	COG0617	tRNA 3'-terminal CCA addition
ETA57_RS12775	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS12780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETA57_RS12785	COG1803	Methylglyoxal synthase
ETA57_RS12790	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETA57_RS12795	COG1694	Mazg nucleotide pyrophosphohydrolase
ETA57_RS12800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS12810	COG4347	Protein of unknown function (DUF1405)
ETA57_RS12815	COG2010	Cytochrome c
ETA57_RS12815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETA57_RS12820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETA57_RS12825	COG0723	plastoquinol--plastocyanin reductase activity
ETA57_RS12835	COG5582	Belongs to the UPF0302 family
ETA57_RS12840	COG0457	Tetratricopeptide repeat
ETA57_RS12845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETA57_RS12850	COG0287	Prephenate dehydrogenase
ETA57_RS12855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETA57_RS12860	COG0159	tryptophan synthase activity
ETA57_RS12865	COG0133	tryptophan synthase activity
ETA57_RS12870	COG0135	phosphoribosylanthranilate isomerase activity
ETA57_RS12875	COG0134	indole-3-glycerol-phosphate synthase activity
ETA57_RS12880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETA57_RS12885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETA57_RS12890	COG4401	Chorismate mutase type I
ETA57_RS12895	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETA57_RS12900	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETA57_RS12905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETA57_RS12910	COG0105	UTP biosynthetic process
ETA57_RS12915	COG0142	geranyltranstransferase activity
ETA57_RS12920	COG2226	methyltransferase
ETA57_RS12925	COG0142	geranyltranstransferase activity
ETA57_RS12940	COG0776	regulation of translation
ETA57_RS12945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ETA57_RS12965	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETA57_RS12970	COG1160	GTP binding
ETA57_RS12995	COG1304	FMN binding
ETA57_RS13000	COG0539	negative regulation of cytoplasmic translation
ETA57_RS13005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETA57_RS13010	COG2959	enzyme of heme biosynthesis
ETA57_RS13015	COG3773	Cell wall hydrolase
ETA57_RS13015	COG3409	Peptidoglycan-binding domain 1 protein
ETA57_RS13020	COG2339	peptidase activity
ETA57_RS13030	COG0492	ferredoxin-NADP+ reductase activity
ETA57_RS13035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETA57_RS13040	COG4862	establishment of competence for transformation
ETA57_RS13045	COG1408	metallophosphoesterase
ETA57_RS13055	COG1388	LysM domain
ETA57_RS13065	COG0514	ATP-dependent DNA helicase (RecQ)
ETA57_RS13070	COG4955	Helix-turn-helix domain
ETA57_RS13075	COG1141	Ferredoxin
ETA57_RS13080	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETA57_RS13085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETA57_RS13090	COG0739	heme binding
ETA57_RS13100	COG1595	DNA-templated transcription, initiation
ETA57_RS13105	COG1316	TRANSCRIPTIONal
ETA57_RS13120	COG5002	protein histidine kinase activity
ETA57_RS13125	COG0745	RESPONSE REGULATOR receiver
ETA57_RS13130	COG5002	protein histidine kinase activity
ETA57_RS13135	COG0745	RESPONSE REGULATOR receiver
ETA57_RS13140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETA57_RS13145	COG1333	cytochrome c biogenesis protein
ETA57_RS13150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS13155	COG1187	pseudouridine synthase activity
ETA57_RS13160	COG0700	Nucleoside recognition
ETA57_RS13165	COG2715	membrane protein required for spore maturation
ETA57_RS13170	COG1686	Belongs to the peptidase S11 family
ETA57_RS13180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETA57_RS13185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ETA57_RS13195	COG1547	Domain of unknown function (DUF309)
ETA57_RS13200	COG0456	acetyltransferase
ETA57_RS13205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ETA57_RS13210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETA57_RS13210	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ETA57_RS13215	COG0307	riboflavin synthase, alpha
ETA57_RS13220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETA57_RS13220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ETA57_RS13245	COG0457	Tetratricopeptide repeat
ETA57_RS13250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETA57_RS13255	COG4086	secreted protein
ETA57_RS13260	COG4195	phage-related replication protein
ETA57_RS13265	COG0019	diaminopimelate decarboxylase activity
ETA57_RS13275	COG0697	spore germination
ETA57_RS13290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETA57_RS13325	COG1686	Belongs to the peptidase S11 family
ETA57_RS13330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETA57_RS13335	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ETA57_RS13340	COG4974	Belongs to the 'phage' integrase family
ETA57_RS13350	COG0735	belongs to the Fur family
ETA57_RS13355	COG1300	Membrane
ETA57_RS13360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS13380	COG2153	protein acetylation
ETA57_RS13385	COG1379	DNA repair
ETA57_RS13390	COG0494	nUDIX hydrolase
ETA57_RS13400	COG1309	transcriptional regulator
ETA57_RS13410	COG0667	Aldo Keto reductase
ETA57_RS13420	COG1073	alpha beta
ETA57_RS13430	COG4918	Iron-sulphur cluster biosynthesis
ETA57_RS13440	COG0456	acetyltransferase
ETA57_RS13440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETA57_RS13445	COG2329	Antibiotic biosynthesis monooxygenase
ETA57_RS13455	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ETA57_RS13465	COG0747	negative chemotaxis
ETA57_RS13470	COG0601	transmembrane transport
ETA57_RS13475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS13480	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS13485	COG0534	Mate efflux family protein
ETA57_RS13500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETA57_RS13510	COG2211	Major facilitator Superfamily
ETA57_RS13515	COG0346	lactoylglutathione lyase activity
ETA57_RS13520	COG1072	(Pantothenic acid kinase))
ETA57_RS13535	COG1131	(ABC) transporter
ETA57_RS13555	COG4195	phage-related replication protein
ETA57_RS13565	COG0300	oxidoreductase activity
ETA57_RS13570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS13575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA57_RS13580	COG4187	Peptidase family M20/M25/M40
ETA57_RS13585	COG1902	pentaerythritol trinitrate reductase activity
ETA57_RS13590	COG0596	Alpha beta hydrolase
ETA57_RS13595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETA57_RS13600	COG1234	tRNA 3'-trailer cleavage
ETA57_RS13605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETA57_RS13620	COG2358	TRAP transporter, solute receptor (TAXI family
ETA57_RS13625	COG2188	Transcriptional regulator
ETA57_RS13630	COG2723	6-phospho-beta-galactosidase activity
ETA57_RS13635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS13640	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETA57_RS13645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS13650	COG1785	Belongs to the alkaline phosphatase family
ETA57_RS13655	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS13660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETA57_RS13665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETA57_RS13675	COG0706	membrane insertase activity
ETA57_RS13680	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETA57_RS13685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETA57_RS13690	COG4129	membrane
ETA57_RS13695	COG1126	abc transporter atp-binding protein
ETA57_RS13700	COG0765	amino acid transport
ETA57_RS13705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETA57_RS13715	COG1597	lipid kinase activity
ETA57_RS13720	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETA57_RS13725	COG0022	dehydrogenase e1 component
ETA57_RS13730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETA57_RS13735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETA57_RS13740	COG3426	butyrate kinase activity
ETA57_RS13750	COG0280	phosphate acetyltransferase
ETA57_RS13755	COG3290	protein histidine kinase activity
ETA57_RS13755	COG3829	transcription factor binding
ETA57_RS13765	COG0584	glycerophosphoryl diester phosphodiesterase
ETA57_RS13770	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS13785	COG1045	serine acetyltransferase
ETA57_RS13795	COG0745	RESPONSE REGULATOR receiver
ETA57_RS13800	COG0750	zinc metalloprotease
ETA57_RS13805	COG0497	DNA recombination
ETA57_RS13810	COG1438	arginine binding
ETA57_RS13815	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETA57_RS13820	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETA57_RS13825	COG0142	geranyltranstransferase activity
ETA57_RS13830	COG1722	exodeoxyribonuclease VII activity
ETA57_RS13835	COG1570	exodeoxyribonuclease VII activity
ETA57_RS13840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETA57_RS13845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETA57_RS13850	COG1302	Protein conserved in bacteria
ETA57_RS13855	COG0439	Biotin carboxylase
ETA57_RS13860	COG0511	ligase activity, forming carbon-carbon bonds
ETA57_RS13900	COG3854	ATPases associated with a variety of cellular activities
ETA57_RS13910	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETA57_RS13915	COG0006	proline dipeptidase activity
ETA57_RS13920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ETA57_RS13930	COG3872	metal-dependent enzyme
ETA57_RS13940	COG1752	Esterase of the alpha-beta hydrolase superfamily
ETA57_RS13945	COG1321	iron dependent repressor
ETA57_RS13950	COG0095	Lipoate-protein ligase
ETA57_RS13955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA57_RS13960	COG2113	Glycine betaine
ETA57_RS13965	COG4176	ABC-type proline glycine betaine transport system permease component
ETA57_RS13970	COG4175	Glycine betaine
ETA57_RS13970	COG0517	IMP dehydrogenase activity
ETA57_RS13975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETA57_RS13980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETA57_RS13985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETA57_RS13990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETA57_RS14015	COG0681	Belongs to the peptidase S26 family
ETA57_RS14040	COG4940	Competence protein ComGF
ETA57_RS14050	COG4970	Tfp pilus assembly protein FimT
ETA57_RS14055	COG4537	Required for transformation and DNA binding
ETA57_RS14060	COG1459	type II secretion system
ETA57_RS14065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETA57_RS14070	COG1366	Belongs to the anti-sigma-factor antagonist family
ETA57_RS14080	COG1393	Belongs to the ArsC family
ETA57_RS14090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS14100	COG0011	TIGRFAM Protein of
ETA57_RS14110	COG2866	Carboxypeptidase
ETA57_RS14115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS14120	COG1368	sulfuric ester hydrolase activity
ETA57_RS14125	COG1940	carbohydrate kinase activity
ETA57_RS14130	COG4483	Protein conserved in bacteria
ETA57_RS14135	COG0697	spore germination
ETA57_RS14140	COG0705	Rhomboid family
ETA57_RS14140	COG0457	Tetratricopeptide repeat
ETA57_RS14145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETA57_RS14150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETA57_RS14155	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS14170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETA57_RS14175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETA57_RS14180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETA57_RS14185	COG0581	inorganic phosphate transmembrane transporter activity
ETA57_RS14190	COG0573	inorganic phosphate transmembrane transporter activity
ETA57_RS14195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETA57_RS14200	COG0768	penicillin binding
ETA57_RS14205	COG0477	Major facilitator Superfamily
ETA57_RS14210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETA57_RS14215	COG2839	Protein conserved in bacteria
ETA57_RS14220	COG5521	maltodextrose utilization protein MalA
ETA57_RS14225	COG1388	LysM domain
ETA57_RS14230	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETA57_RS14235	COG4709	membrane
ETA57_RS14240	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ETA57_RS14245	COG0735	belongs to the Fur family
ETA57_RS14250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETA57_RS14255	COG1121	(ABC) transporter
ETA57_RS14260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS14270	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETA57_RS14275	COG0513	Belongs to the DEAD box helicase family
ETA57_RS14285	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETA57_RS14290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETA57_RS14295	COG2384	SAM-dependent methyltransferase
ETA57_RS14345	COG5444	nuclease activity
ETA57_RS14360	COG2010	Cytochrome c
ETA57_RS14365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETA57_RS14370	COG0358	DNA primase activity
ETA57_RS14375	COG1671	Belongs to the UPF0178 family
ETA57_RS14380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ETA57_RS14385	COG0517	IMP dehydrogenase activity
ETA57_RS14390	COG0751	glycine-tRNA ligase activity
ETA57_RS14395	COG0752	glycyl-tRNA synthetase alpha subunit
ETA57_RS14400	COG1381	Involved in DNA repair and RecF pathway recombination
ETA57_RS14410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETA57_RS14415	COG0295	cytidine deaminase activity
ETA57_RS14420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETA57_RS14425	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETA57_RS14430	COG1480	7TM receptor with intracellular HD hydrolase
ETA57_RS14435	COG1702	phosphate starvation-inducible protein PhoH
ETA57_RS14440	COG0561	phosphatase activity
ETA57_RS14455	COG4864	UPF0365 protein
ETA57_RS14460	COG1030	water channel activity
ETA57_RS14465	COG1610	YqeY-like protein
ETA57_RS14470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETA57_RS14475	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETA57_RS14480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETA57_RS14485	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETA57_RS14490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETA57_RS14495	COG2264	protein methyltransferase activity
ETA57_RS14500	COG0484	heat shock protein binding
ETA57_RS14505	COG0443	Heat shock 70 kDa protein
ETA57_RS14510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETA57_RS14515	COG1420	regulation of RNA biosynthetic process
ETA57_RS14520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETA57_RS14525	COG0481	GTPase activity
ETA57_RS14535	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS14540	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ETA57_RS14545	COG0268	Binds directly to 16S ribosomal RNA
ETA57_RS14550	COG1466	dna polymerase III delta subunit
ETA57_RS14560	COG2333	competence protein COMEC
ETA57_RS14560	COG0658	competence protein
ETA57_RS14565	COG2131	deaminase
ETA57_RS14570	COG1555	photosystem II stabilization
ETA57_RS14570	COG1596	polysaccharide export
ETA57_RS14575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETA57_RS14580	COG2226	methyltransferase
ETA57_RS14585	COG0799	negative regulation of ribosome biogenesis
ETA57_RS14590	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETA57_RS14595	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETA57_RS14600	COG1534	Rna-binding protein
ETA57_RS14605	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETA57_RS14610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETA57_RS14615	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETA57_RS14625	COG2755	lipolytic protein G-D-S-L family
ETA57_RS14630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA57_RS14635	COG5609	conserved protein (DUF2294)
ETA57_RS14640	COG3383	formate dehydrogenase (NAD+) activity
ETA57_RS14645	COG2427	Protein of unknown function (DUF1641)
ETA57_RS14675	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS14720	COG1136	(ABC) transporter
ETA57_RS14725	COG0577	efflux transmembrane transporter activity
ETA57_RS14805	COG2197	response regulator
ETA57_RS14810	COG4585	Histidine kinase
ETA57_RS14815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS14820	COG0730	response to heat
ETA57_RS14825	COG0425	Belongs to the sulfur carrier protein TusA family
ETA57_RS14830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA57_RS14830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS14835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA57_RS14835	COG0425	Belongs to the sulfur carrier protein TusA family
ETA57_RS14840	COG2210	Belongs to the sulfur carrier protein TusA family
ETA57_RS14845	COG1937	Protein conserved in bacteria
ETA57_RS14890	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETA57_RS14915	COG1942	4-Oxalocrotonate Tautomerase
ETA57_RS14925	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ETA57_RS14930	COG1733	regulation of RNA biosynthetic process
ETA57_RS14935	COG3239	Fatty acid desaturase
ETA57_RS14940	COG4585	Histidine kinase
ETA57_RS14945	COG2197	response regulator
ETA57_RS14950	COG0492	ferredoxin-NADP+ reductase activity
ETA57_RS14955	COG0747	negative chemotaxis
ETA57_RS14960	COG0601	transmembrane transport
ETA57_RS14965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETA57_RS14970	COG0444	Belongs to the ABC transporter superfamily
ETA57_RS14975	COG4608	Belongs to the ABC transporter superfamily
ETA57_RS14995	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS15015	COG0730	response to heat
ETA57_RS15030	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS15035	COG1621	beta-fructofuranosidase activity
ETA57_RS15040	COG3716	PTS system mannose fructose sorbose family IID component
ETA57_RS15045	COG3715	PTS system
ETA57_RS15050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS15055	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS15060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ETA57_RS15060	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ETA57_RS15080	COG2169	Transcriptional regulator
ETA57_RS15085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETA57_RS15090	COG0656	L-ascorbic acid biosynthetic process
ETA57_RS15100	COG1733	regulation of RNA biosynthetic process
ETA57_RS15105	COG3340	Belongs to the peptidase S51 family
ETA57_RS15110	COG1587	Uroporphyrinogen-III synthase
ETA57_RS15120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS15130	COG2814	Major facilitator Superfamily
ETA57_RS15140	COG2124	cytochrome p450
ETA57_RS15140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETA57_RS15145	COG1309	transcriptional regulator
ETA57_RS15150	COG1404	Belongs to the peptidase S8 family
ETA57_RS15155	COG2226	methyltransferase
ETA57_RS15180	COG0626	cystathionine gamma-synthase activity
ETA57_RS15185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA57_RS15190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETA57_RS15195	COG2226	methyltransferase
ETA57_RS15210	COG0768	penicillin binding
ETA57_RS15215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETA57_RS15220	COG0572	uridine kinase
ETA57_RS15225	COG0826	peptidase U32
ETA57_RS15230	COG0826	peptidase U32
ETA57_RS15235	COG4122	O-methyltransferase activity
ETA57_RS15240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETA57_RS15245	COG3906	Belongs to the UPF0473 family
ETA57_RS15250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETA57_RS15255	COG4472	Bacterial protein of unknown function (DUF965)
ETA57_RS15260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETA57_RS15265	COG0628	permease
ETA57_RS15280	COG3881	PFAM PRC-barrel domain
ETA57_RS15285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETA57_RS15290	COG0457	Tetratricopeptide repeat
ETA57_RS15295	COG0482	sulfurtransferase activity
ETA57_RS15300	COG1104	cysteine desulfurase activity
ETA57_RS15305	COG1959	2 iron, 2 sulfur cluster binding
ETA57_RS15310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETA57_RS15315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ETA57_RS15325	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETA57_RS15330	COG0124	histidyl-tRNA synthetase
ETA57_RS15335	COG4991	sh3 domain protein
ETA57_RS15335	COG3103	Sh3 type 3 domain protein
ETA57_RS15335	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS15340	COG1490	D-aminoacyl-tRNA deacylase activity
ETA57_RS15345	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ETA57_RS15350	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETA57_RS15355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETA57_RS15355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETA57_RS15360	COG5416	Lipopolysaccharide assembly protein A domain
ETA57_RS15365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETA57_RS15365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETA57_RS15375	COG2244	polysaccharide biosynthetic process
ETA57_RS15380	COG2323	membrane
ETA57_RS15390	COG1862	Preprotein translocase
ETA57_RS15395	COG0343	queuine tRNA-ribosyltransferase activity
ETA57_RS15400	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ETA57_RS15410	COG2255	four-way junction helicase activity
ETA57_RS15415	COG0632	four-way junction helicase activity
ETA57_RS15425	COG2112	serine threonine protein kinase
ETA57_RS15435	COG2318	DinB family
ETA57_RS15440	COG4195	phage-related replication protein
ETA57_RS15455	COG0217	transcriptional regulatory protein
ETA57_RS15465	COG1388	LysM domain
ETA57_RS15470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETA57_RS15475	COG0157	Belongs to the NadC ModD family
ETA57_RS15480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETA57_RS15485	COG1104	cysteine desulfurase activity
ETA57_RS15490	COG1827	regulation of RNA biosynthetic process
ETA57_RS15495	COG0077	Prephenate dehydratase
ETA57_RS15500	COG4492	Belongs to the UPF0735 family
ETA57_RS15505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETA57_RS15510	COG3290	protein histidine kinase activity
ETA57_RS15515	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETA57_RS15520	COG2868	ribosomal protein
ETA57_RS15525	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETA57_RS15530	COG1994	Peptidase M50
ETA57_RS15535	COG0739	heme binding
ETA57_RS15540	COG3832	glyoxalase III activity
ETA57_RS15545	COG0640	Transcriptional regulator
ETA57_RS15550	COG2894	cell division
ETA57_RS15555	COG0850	regulation of cytokinetic process
ETA57_RS15560	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ETA57_RS15570	COG1077	Cell shape determining protein MreB Mrl
ETA57_RS15590	COG0457	Tetratricopeptide repeat
ETA57_RS15595	COG5444	nuclease activity
ETA57_RS15640	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETA57_RS15695	COG1802	Transcriptional regulator
ETA57_RS15695	COG4626	Terminase
ETA57_RS15815	COG0424	maF-like protein
ETA57_RS15825	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETA57_RS15830	COG0285	dihydrofolate synthase activity
ETA57_RS15835	COG0525	valine-tRNA ligase activity
ETA57_RS15845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA57_RS15850	COG1388	LysM domain
ETA57_RS15855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETA57_RS15860	COG0113	porphobilinogen synthase activity
ETA57_RS15865	COG1587	Uroporphyrinogen-III synthase
ETA57_RS15870	COG0181	hydroxymethylbilane synthase activity
ETA57_RS15875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETA57_RS15880	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETA57_RS15890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ETA57_RS15895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETA57_RS15900	COG1067	ATP-dependent peptidase activity
ETA57_RS15900	COG0470	DNA polymerase III
ETA57_RS15905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETA57_RS15910	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETA57_RS15915	COG1477	protein flavinylation
ETA57_RS15915	COG0457	Tetratricopeptide repeat
ETA57_RS15920	COG0066	3-isopropylmalate dehydratase activity
ETA57_RS15925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETA57_RS15930	COG0473	3-isopropylmalate dehydrogenase activity
ETA57_RS15935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETA57_RS15940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETA57_RS15945	COG0440	acetolactate synthase activity
ETA57_RS15950	COG0028	Belongs to the TPP enzyme family
ETA57_RS15955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA57_RS15965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETA57_RS15985	COG5518	Phage portal protein
ETA57_RS15990	COG1783	phage Terminase large subunit
ETA57_RS16045	COG5444	nuclease activity
ETA57_RS16070	COG0622	Phosphoesterase
ETA57_RS16075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETA57_RS16080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETA57_RS16085	COG5401	PFAM Sporulation and spore germination
ETA57_RS16090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ETA57_RS16095	COG1846	Transcriptional regulator
ETA57_RS16100	COG2197	response regulator
ETA57_RS16105	COG4221	oxidoreductase activity
ETA57_RS16110	COG0824	Thioesterase
ETA57_RS16115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETA57_RS16120	COG1053	succinate dehydrogenase
ETA57_RS16125	COG2009	succinate dehydrogenase
ETA57_RS16130	COG1719	4-vinyl reductase, 4VR
ETA57_RS16135	COG0527	aspartate kinase activity
ETA57_RS16145	COG0322	excinuclease ABC activity
ETA57_RS16150	COG3118	belongs to the thioredoxin family
ETA57_RS16155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ETA57_RS16160	COG2086	electron transfer activity
ETA57_RS16165	COG1024	Enoyl-CoA hydratase
ETA57_RS16170	COG1309	transcriptional regulator
ETA57_RS16175	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS16180	COG3766	membrane
ETA57_RS16185	COG1193	negative regulation of DNA recombination
ETA57_RS16190	COG1796	DNA polymerase
ETA57_RS16190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETA57_RS16195	COG1286	toxin biosynthetic process
ETA57_RS16200	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ETA57_RS16205	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ETA57_RS16235	COG1137	ATPase activity
ETA57_RS16250	COG0072	phenylalanine-tRNA ligase activity
ETA57_RS16250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA57_RS16255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETA57_RS16260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETA57_RS16270	COG1966	Carbon starvation protein
ETA57_RS16285	COG0395	ABC-type sugar transport system, permease component
ETA57_RS16290	COG1175	transmembrane transport
ETA57_RS16295	COG1653	transport
ETA57_RS16300	COG0371	Dehydrogenase
ETA57_RS16305	COG0235	Class ii aldolase
ETA57_RS16315	COG2160	L-arabinose isomerase activity
ETA57_RS16320	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA57_RS16325	COG1363	Peptidase, m42
ETA57_RS16335	COG3326	Membrane
ETA57_RS16340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETA57_RS16345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETA57_RS16350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETA57_RS16355	COG1346	cytolysis
ETA57_RS16365	COG3540	Alkaline phosphatase
ETA57_RS16370	COG3279	Response regulator of the LytR AlgR family
ETA57_RS16375	COG3275	phosphorelay sensor kinase activity
ETA57_RS16385	COG1011	Hydrolase
ETA57_RS16390	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETA57_RS16400	COG0398	Pfam SNARE associated Golgi protein
ETA57_RS16405	COG1484	DNA-dependent DNA replication
ETA57_RS16410	COG3611	Membrane attachment protein
ETA57_RS16415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETA57_RS16430	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ETA57_RS16435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETA57_RS16440	COG3866	Pectate lyase
ETA57_RS16445	COG0237	dephospho-CoA kinase activity
ETA57_RS16450	COG1971	Probably functions as a manganese efflux pump
ETA57_RS16455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETA57_RS16460	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA57_RS16460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETA57_RS16465	COG5002	protein histidine kinase activity
ETA57_RS16470	COG0745	RESPONSE REGULATOR receiver
ETA57_RS16475	COG0039	L-malate dehydrogenase activity
ETA57_RS16480	COG0538	isocitrate dehydrogenase activity
ETA57_RS16485	COG0372	Belongs to the citrate synthase family
ETA57_RS16490	COG2707	UPF0756 membrane protein
ETA57_RS16495	COG0628	permease
ETA57_RS16500	COG3030	protein affecting phage T7 exclusion by the F plasmid
ETA57_RS16510	COG0205	6-phosphofructokinase activity
ETA57_RS16515	COG0825	malonyl-CoA metabolic process
ETA57_RS16520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETA57_RS16525	COG0281	malic enzyme
ETA57_RS16530	COG0587	DNA-directed DNA polymerase activity
ETA57_RS16550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETA57_RS16560	COG4109	DRTGG domain
ETA57_RS16565	COG1695	Transcriptional regulator
ETA57_RS16570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETA57_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS16580	COG0165	Argininosuccinate lyase
ETA57_RS16585	COG0137	argininosuccinate synthase activity
ETA57_RS16590	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETA57_RS16595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETA57_RS16600	COG0827	DNA restriction-modification system
ETA57_RS16605	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETA57_RS16610	COG3874	Sporulation protein YtfJ
ETA57_RS16620	COG1714	RDD family
ETA57_RS16625	COG0616	signal peptide processing
ETA57_RS16630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETA57_RS16635	COG1566	PFAM secretion protein HlyD family protein
ETA57_RS16640	COG0477	Major facilitator Superfamily
ETA57_RS16650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETA57_RS16660	COG0301	tRNA thio-modification
ETA57_RS16665	COG1104	cysteine desulfurase activity
ETA57_RS16670	COG1114	Component of the transport system for branched-chain amino acids
ETA57_RS16680	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ETA57_RS16685	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETA57_RS16690	COG1309	transcriptional regulator
ETA57_RS16695	COG1956	GAF domain-containing protein
ETA57_RS16705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETA57_RS16720	COG3152	Membrane
ETA57_RS16725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETA57_RS16730	COG1522	sequence-specific DNA binding
ETA57_RS16735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETA57_RS16740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETA57_RS16745	COG0454	-acetyltransferase
ETA57_RS16750	COG0517	IMP dehydrogenase activity
ETA57_RS16755	COG0123	including yeast histone deacetylase and acetoin utilization protein
ETA57_RS16760	COG1360	Flagellar Motor Protein
ETA57_RS16765	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ETA57_RS16770	COG1609	Transcriptional regulator
ETA57_RS16775	COG1605	Chorismate mutase
ETA57_RS16775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETA57_RS16785	COG3118	belongs to the thioredoxin family
ETA57_RS16790	COG4980	gas vesicle protein
ETA57_RS16795	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ETA57_RS16800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ETA57_RS16805	COG1674	ftsk spoiiie
ETA57_RS16810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETA57_RS16815	COG4848	Belongs to the UPF0354 family
ETA57_RS16820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS16830	COG1363	Peptidase, m42
ETA57_RS16835	COG5584	Small secreted protein
ETA57_RS16840	COG0281	malic enzyme
ETA57_RS16845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETA57_RS16850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETA57_RS16860	COG0510	thiamine kinase activity
ETA57_RS16865	COG1523	belongs to the glycosyl hydrolase 13 family
ETA57_RS16870	COG1597	lipid kinase activity
ETA57_RS16880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETA57_RS16885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETA57_RS16900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA57_RS16905	COG2252	PERMEase
ETA57_RS16910	COG1349	DNA-binding transcription factor activity
ETA57_RS16915	COG1187	pseudouridine synthase activity
ETA57_RS16920	COG2244	polysaccharide biosynthetic process
ETA57_RS16925	COG2081	HI0933 family
ETA57_RS16930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ETA57_RS16940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETA57_RS16955	COG5578	integral membrane protein
ETA57_RS16960	COG0673	inositol 2-dehydrogenase activity
ETA57_RS16965	COG1653	transport
ETA57_RS16970	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETA57_RS16975	COG4209	transmembrane transport
ETA57_RS16980	COG2207	Transcriptional regulator
ETA57_RS16985	COG1653	transport
ETA57_RS16990	COG0395	ABC-type sugar transport system, permease component
ETA57_RS16995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA57_RS17000	COG1073	alpha beta
ETA57_RS17010	COG0583	DNA-binding transcription factor activity
ETA57_RS17015	COG0346	lactoylglutathione lyase activity
ETA57_RS17020	COG0495	leucyl-tRNA aminoacylation
ETA57_RS17030	COG2814	Major facilitator Superfamily
ETA57_RS17040	COG2433	Pfam Transposase IS66
ETA57_RS17045	COG0577	efflux transmembrane transporter activity
ETA57_RS17050	COG1136	(ABC) transporter
ETA57_RS17060	COG1131	(ABC) transporter
ETA57_RS17065	COG1725	Transcriptional regulator
ETA57_RS17075	COG1242	4 iron, 4 sulfur cluster binding
ETA57_RS17080	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETA57_RS17085	COG1301	dicarboxylic acid transport
ETA57_RS17095	COG2267	carboxylic ester hydrolase activity
ETA57_RS17100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ETA57_RS17105	COG0671	phosphoesterase, PA-phosphatase related
ETA57_RS17110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA57_RS17110	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS17115	COG0367	asparagine synthase
ETA57_RS17120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETA57_RS17125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETA57_RS17130	COG1301	dicarboxylic acid transport
ETA57_RS17140	COG1506	peptidase
ETA57_RS17145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETA57_RS17150	COG1116	anion transmembrane transporter activity
ETA57_RS17155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETA57_RS17160	COG0494	nUDIX hydrolase
ETA57_RS17170	COG4824	toxin secretion phage lysis holin
ETA57_RS17175	COG0783	Belongs to the Dps family
ETA57_RS17190	COG1854	S-ribosylhomocysteine lyase activity
ETA57_RS17195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETA57_RS17200	COG0288	reversible hydration of carbon dioxide
ETA57_RS17205	COG0523	cobalamin synthesis protein
ETA57_RS17210	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETA57_RS17220	COG0254	rRNA binding
ETA57_RS17225	COG1271	oxidase subunit
ETA57_RS17230	COG1294	oxidase, subunit
ETA57_RS17245	COG4948	Mandelate Racemase Muconate Lactonizing
ETA57_RS17250	COG0318	PFAM AMP-dependent synthetase and ligase
ETA57_RS17255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ETA57_RS17260	COG0596	Alpha beta hydrolase
ETA57_RS17265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ETA57_RS17270	COG1169	isochorismate synthase
ETA57_RS17275	COG1575	Belongs to the MenA family. Type 1 subfamily
ETA57_RS17280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ETA57_RS17285	COG0058	SHG alpha-glucan phosphorylase activity
ETA57_RS17290	COG0297	glycogen (starch) synthase activity
ETA57_RS17295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETA57_RS17300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETA57_RS17305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETA57_RS17430	COG1609	Transcriptional regulator
ETA57_RS17435	COG3859	Proton-coupled thiamine transporter YuaJ
ETA57_RS17440	COG3764	Sortase (surface protein transpeptidase)
ETA57_RS17455	COG0457	Tetratricopeptide repeat
ETA57_RS17460	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETA57_RS17465	COG0569	domain protein
ETA57_RS17470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETA57_RS17480	COG2318	DinB family
ETA57_RS17490	COG1454	alcohol dehydrogenase
ETA57_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS17500	COG1510	regulation of RNA biosynthetic process
ETA57_RS17510	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ETA57_RS17515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ETA57_RS17560	COG1397	ADP-ribosylglycohydrolase
ETA57_RS17595	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ETA57_RS17605	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ETA57_RS17610	COG0726	polysaccharide deacetylase
ETA57_RS17615	COG1408	metallophosphoesterase
ETA57_RS17620	COG1968	undecaprenyl-diphosphatase activity
ETA57_RS17625	COG0628	permease
ETA57_RS17630	COG0673	inositol 2-dehydrogenase activity
ETA57_RS17635	COG0693	protein deglycase activity
ETA57_RS17645	COG0840	transmembrane signaling receptor activity
ETA57_RS17660	COG2070	2-Nitropropane dioxygenase
ETA57_RS17665	COG0432	Pfam Uncharacterised protein family UPF0047
ETA57_RS17670	COG0366	Alpha amylase catalytic
ETA57_RS17685	COG5297	Belongs to the glycosyl hydrolase family 6
ETA57_RS17690	COG1253	flavin adenine dinucleotide binding
ETA57_RS17695	COG2738	Putative neutral zinc metallopeptidase
ETA57_RS17710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETA57_RS17735	COG0166	Belongs to the GPI family
ETA57_RS17740	COG1979	alcohol dehydrogenase
ETA57_RS17745	COG2155	Conserved Protein
ETA57_RS17750	COG1098	S1 RNA binding domain
ETA57_RS17755	COG0436	Aminotransferase
ETA57_RS17760	COG1522	sequence-specific DNA binding
ETA57_RS17765	COG2267	carboxylic ester hydrolase activity
ETA57_RS17780	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ETA57_RS17795	COG5018	Exonuclease
ETA57_RS17800	COG2814	Major facilitator Superfamily
ETA57_RS17805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETA57_RS17810	COG3011	Protein conserved in bacteria
ETA57_RS17820	COG3290	protein histidine kinase activity
ETA57_RS17825	COG4565	transcriptional regulatory protein
ETA57_RS17835	COG1183	phosphatidylcholine synthase activity
ETA57_RS17840	COG0586	Pfam SNARE associated Golgi protein
ETA57_RS17845	COG0688	phosphatidylethanolamine metabolic process
ETA57_RS17855	COG3493	citrate carrier protein
ETA57_RS17865	COG2111	Na H antiporter
ETA57_RS17865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETA57_RS17870	COG2111	Na H antiporter
ETA57_RS17875	COG1006	Multisubunit Na H antiporter MnhC subunit
ETA57_RS17880	COG0651	ATP synthesis coupled electron transport
ETA57_RS17885	COG1863	multisubunit Na H antiporter MnhE subunit
ETA57_RS17890	COG2212	antiporter activity
ETA57_RS17895	COG1320	monovalent cation:proton antiporter activity
ETA57_RS17900	COG2050	protein possibly involved in aromatic compounds catabolism
ETA57_RS17905	COG2197	response regulator
ETA57_RS17910	COG4585	Histidine kinase
ETA57_RS17920	COG0142	geranyltranstransferase activity
ETA57_RS17940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ETA57_RS17945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETA57_RS17950	COG1335	isochorismatase
ETA57_RS17955	COG5506	Protein of unknown function (DUF1694)
ETA57_RS17970	COG0628	permease
ETA57_RS17975	COG1959	2 iron, 2 sulfur cluster binding
ETA57_RS17980	COG0657	acetylesterase activity
ETA57_RS17990	COG1418	mRNA catabolic process
ETA57_RS17995	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS18005	COG1511	domain protein
ETA57_RS18010	COG0433	COG0433 Predicted ATPase
ETA57_RS18010	COG1674	ftsk spoiiie
ETA57_RS18015	COG4499	WXG100 protein secretion system (Wss), protein YukC
ETA57_RS18020	COG5417	Belongs to the EsaB family
ETA57_RS18025	COG4842	Belongs to the WXG100 family
ETA57_RS18030	COG1115	amino acid carrier protein
ETA57_RS18035	COG2508	Transcriptional regulator
ETA57_RS18035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ETA57_RS18040	COG0686	Belongs to the AlaDH PNT family
ETA57_RS18050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETA57_RS18055	COG1268	BioY protein
ETA57_RS18060	COG2056	Na+-H+ antiporter family
ETA57_RS18065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETA57_RS18070	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ETA57_RS18075	COG3584	3D domain protein
ETA57_RS18085	COG1252	NADH dehydrogenase
ETA57_RS18090	COG0492	ferredoxin-NADP+ reductase activity
ETA57_RS18210	COG0582	viral genome integration into host DNA
ETA57_RS18235	COG0316	Belongs to the HesB IscA family
ETA57_RS18240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETA57_RS18245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETA57_RS18250	COG4844	belongs to the
ETA57_RS18255	COG1252	NADH dehydrogenase
ETA57_RS18260	COG5646	InterPro IPR014922
ETA57_RS18270	COG3479	Phenolic acid decarboxylase
ETA57_RS18280	COG4837	Protein of unknown function (DUF1462)
ETA57_RS18285	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ETA57_RS18295	COG0083	homoserine kinase activity
ETA57_RS18300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETA57_RS18305	COG0460	homoserine dehydrogenase
ETA57_RS18315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ETA57_RS18320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETA57_RS18325	COG0647	UMP catabolic process
ETA57_RS18330	COG2445	Protein of unknown function DUF86
ETA57_RS18335	COG4470	Protein conserved in bacteria
ETA57_RS18350	COG0739	heme binding
ETA57_RS18365	COG0733	neurotransmitter:sodium symporter activity
ETA57_RS18375	COG3377	Domain of unknown function (DUF1805)
ETA57_RS18380	COG0737	Belongs to the 5'-nucleotidase family
ETA57_RS18385	COG0730	response to heat
ETA57_RS18390	COG1801	Protein of unknown function DUF72
ETA57_RS18400	COG3226	Transcriptional regulator
ETA57_RS18410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETA57_RS18415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETA57_RS18420	COG2508	Transcriptional regulator
ETA57_RS18425	COG2814	Major facilitator Superfamily
ETA57_RS18430	COG1288	antiporter activity
ETA57_RS18435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETA57_RS18440	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETA57_RS18445	COG2356	endonuclease I
ETA57_RS18455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETA57_RS18470	COG0457	Tetratricopeptide repeat
ETA57_RS18475	COG0719	Fe-S assembly protein
ETA57_RS18480	COG0822	iron-sulfur transferase activity
ETA57_RS18485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETA57_RS18490	COG0719	Fe-S assembly protein
ETA57_RS18495	COG0396	ATPase activity
ETA57_RS18505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETA57_RS18510	COG1464	Belongs to the NlpA lipoprotein family
ETA57_RS18515	COG2011	ABC-type metal ion transport system permease component
ETA57_RS18520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ETA57_RS18530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETA57_RS18535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ETA57_RS18545	COG0509	glycine decarboxylation via glycine cleavage system
ETA57_RS18550	COG1393	Belongs to the ArsC family
ETA57_RS18555	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS18560	COG0183	Belongs to the thiolase family
ETA57_RS18565	COG1024	Enoyl-CoA hydratase
ETA57_RS18565	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETA57_RS18580	COG5577	PFAM Coat F domain
ETA57_RS18595	COG1120	ATPase activity
ETA57_RS18600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS18605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS18610	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS18625	COG1686	Belongs to the peptidase S11 family
ETA57_RS18630	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS18635	COG0783	Belongs to the Dps family
ETA57_RS18640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA57_RS18645	COG0745	RESPONSE REGULATOR receiver
ETA57_RS18650	COG2205	protein histidine kinase activity
ETA57_RS18650	COG2770	Histidine kinase
ETA57_RS18655	COG1309	transcriptional regulator
ETA57_RS18660	COG0114	fumarate hydratase activity
ETA57_RS18670	COG0697	spore germination
ETA57_RS18675	COG0814	amino acid
ETA57_RS18690	COG2197	response regulator
ETA57_RS18695	COG4585	Histidine kinase
ETA57_RS18700	COG4758	membrane
ETA57_RS18710	COG1842	Phage shock protein A
ETA57_RS18715	COG4758	membrane
ETA57_RS18720	COG4677	pectinesterase activity
ETA57_RS18725	COG2096	Adenosyltransferase
ETA57_RS18730	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS18740	COG1454	alcohol dehydrogenase
ETA57_RS18745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETA57_RS18750	COG1120	ATPase activity
ETA57_RS18755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS18760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS18765	COG1802	Transcriptional regulator
ETA57_RS18770	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS18775	COG2258	MOSC domain
ETA57_RS18780	COG0583	DNA-binding transcription factor activity
ETA57_RS18795	COG2721	sulfolactate sulfo-lyase activity
ETA57_RS18800	COG0246	Mannitol dehydrogenase
ETA57_RS18805	COG1609	Transcriptional regulator
ETA57_RS18810	COG2211	Major facilitator Superfamily
ETA57_RS18815	COG1904	glucuronate isomerase
ETA57_RS18820	COG2205	protein histidine kinase activity
ETA57_RS18825	COG0745	RESPONSE REGULATOR receiver
ETA57_RS18830	COG1120	ATPase activity
ETA57_RS18835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS18840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS18845	COG0531	amino acid
ETA57_RS18855	COG1988	membrane-bound metal-dependent
ETA57_RS18860	COG1368	sulfuric ester hydrolase activity
ETA57_RS18865	COG2814	Major facilitator Superfamily
ETA57_RS18870	COG0656	L-ascorbic acid biosynthetic process
ETA57_RS18875	COG1940	carbohydrate kinase activity
ETA57_RS18880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETA57_RS18890	COG3973	AAA domain
ETA57_RS18895	COG2860	membrane
ETA57_RS18900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETA57_RS18900	COG0456	acetyltransferase
ETA57_RS18910	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ETA57_RS18915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ETA57_RS18920	COG2217	Heavy metal translocating P-type atpase
ETA57_RS18925	COG1653	transport
ETA57_RS18930	COG1175	transmembrane transport
ETA57_RS18935	COG0395	ABC-type sugar transport system, permease component
ETA57_RS18940	COG1501	Belongs to the glycosyl hydrolase 31 family
ETA57_RS18945	COG1472	Belongs to the glycosyl hydrolase 3 family
ETA57_RS18950	COG1121	(ABC) transporter
ETA57_RS18955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETA57_RS18960	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETA57_RS18975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ETA57_RS18975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETA57_RS18980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS18980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS18980	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETA57_RS18995	COG2217	Heavy metal translocating P-type atpase
ETA57_RS19000	COG2608	mercury ion transmembrane transporter activity
ETA57_RS19005	COG1937	Protein conserved in bacteria
ETA57_RS19010	COG0693	protein deglycase activity
ETA57_RS19015	COG1349	DNA-binding transcription factor activity
ETA57_RS19020	COG1070	Carbohydrate kinase
ETA57_RS19025	COG4952	isomerase
ETA57_RS19035	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS19035	COG3347	Dehydrogenase
ETA57_RS19040	COG2814	Major facilitator Superfamily
ETA57_RS19045	COG2814	Major facilitator Superfamily
ETA57_RS19055	COG2124	cytochrome p450
ETA57_RS19065	COG1846	Transcriptional regulator
ETA57_RS19075	COG0673	inositol 2-dehydrogenase activity
ETA57_RS19080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ETA57_RS19085	COG1054	Belongs to the UPF0176 family
ETA57_RS19095	COG1191	sigma factor activity
ETA57_RS19105	COG2140	Oxalate decarboxylase
ETA57_RS19150	COG0457	Tetratricopeptide repeat
ETA57_RS19155	COG5444	nuclease activity
ETA57_RS19200	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETA57_RS19210	COG5280	Phage tail tape measure protein TP901
ETA57_RS19210	COG3953	SLT domain
ETA57_RS19270	COG1802	Transcriptional regulator
ETA57_RS19270	COG4626	Terminase
ETA57_RS19415	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETA57_RS19420	COG0557	exoribonuclease II activity
ETA57_RS19425	COG1647	Serine aminopeptidase, S33
ETA57_RS19430	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ETA57_RS19435	COG2002	toxin-antitoxin pair type II binding
ETA57_RS19440	COG1476	TRANSCRIPTIONal
ETA57_RS19445	COG1396	sequence-specific DNA binding
ETA57_RS19450	COG1396	sequence-specific DNA binding
ETA57_RS19455	COG1174	glycine betaine transport
ETA57_RS19460	COG1732	Glycine betaine
ETA57_RS19465	COG1174	glycine betaine transport
ETA57_RS19470	COG1125	glycine betaine transport
ETA57_RS19470	COG0517	IMP dehydrogenase activity
ETA57_RS19475	COG1510	regulation of RNA biosynthetic process
ETA57_RS19480	COG2095	MarC family integral membrane protein
ETA57_RS19485	COG3064	Membrane
ETA57_RS19490	COG4640	response to antibiotic
ETA57_RS19495	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS19515	COG0148	phosphopyruvate hydratase activity
ETA57_RS19520	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ETA57_RS19525	COG0149	triose-phosphate isomerase activity
ETA57_RS19530	COG0126	phosphoglycerate kinase activity
ETA57_RS19540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETA57_RS19545	COG2390	Transcriptional regulator
ETA57_RS19550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA57_RS19555	COG1113	amino acid transport
ETA57_RS19575	COG1556	Lactate utilization protein
ETA57_RS19580	COG1139	Iron-sulfur cluster binding protein
ETA57_RS19585	COG0247	lactate metabolic process
ETA57_RS19590	COG2186	Transcriptional regulator
ETA57_RS19595	COG1620	l-lactate permease
ETA57_RS19600	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ETA57_RS19610	COG5039	Polysaccharide pyruvyl transferase
ETA57_RS19615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA57_RS19620	COG0110	maltose O-acetyltransferase activity
ETA57_RS19625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETA57_RS19630	COG2244	polysaccharide biosynthetic process
ETA57_RS19635	COG1216	Glycosyl transferase, family 2
ETA57_RS19640	COG5039	Polysaccharide pyruvyl transferase
ETA57_RS19645	COG1216	Glycosyl transferase, family 2
ETA57_RS19655	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS19660	COG1215	transferase activity, transferring glycosyl groups
ETA57_RS19665	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS19670	COG1086	Polysaccharide biosynthesis protein
ETA57_RS19675	COG0489	protein tyrosine kinase activity
ETA57_RS19680	COG3944	biosynthesis protein
ETA57_RS19685	COG1396	sequence-specific DNA binding
ETA57_RS19690	COG2249	NAD(P)H dehydrogenase (quinone) activity
ETA57_RS19705	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ETA57_RS19720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETA57_RS19730	COG1733	regulation of RNA biosynthetic process
ETA57_RS19735	COG1902	pentaerythritol trinitrate reductase activity
ETA57_RS19740	COG1621	beta-fructofuranosidase activity
ETA57_RS19745	COG1621	beta-fructofuranosidase activity
ETA57_RS19760	COG0740	serine-type endopeptidase activity
ETA57_RS19765	COG1611	Belongs to the LOG family
ETA57_RS19770	COG1694	Mazg nucleotide pyrophosphohydrolase
ETA57_RS19775	COG1078	dGTPase activity
ETA57_RS19780	COG0659	secondary active sulfate transmembrane transporter activity
ETA57_RS19785	COG0288	reversible hydration of carbon dioxide
ETA57_RS19790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETA57_RS19795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ETA57_RS19800	COG0640	Transcriptional regulator
ETA57_RS19810	COG2732	(Barnase) inhibitor
ETA57_RS19815	COG2162	N-hydroxyarylamine O-acetyltransferase activity
ETA57_RS19820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETA57_RS19825	COG1481	regulation of sporulation
ETA57_RS19830	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ETA57_RS19835	COG1660	Displays ATPase and GTPase activities
ETA57_RS19840	COG1051	belongs to the nudix hydrolase family
ETA57_RS19850	COG0492	ferredoxin-NADP+ reductase activity
ETA57_RS19855	COG0457	Tetratricopeptide repeat
ETA57_RS19860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETA57_RS19865	COG0140	phosphoribosyl-ATP diphosphatase activity
ETA57_RS19865	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ETA57_RS19870	COG0107	imidazoleglycerol-phosphate synthase activity
ETA57_RS19875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETA57_RS19880	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETA57_RS19885	COG0131	Imidazoleglycerol-phosphate dehydratase
ETA57_RS19890	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETA57_RS19895	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETA57_RS19900	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ETA57_RS19905	COG4990	cell redox homeostasis
ETA57_RS19915	COG0110	maltose O-acetyltransferase activity
ETA57_RS19920	COG0546	phosphoglycolate phosphatase activity
ETA57_RS19925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETA57_RS19930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETA57_RS19935	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ETA57_RS19940	COG1846	Transcriptional regulator
ETA57_RS19945	COG2814	Major facilitator Superfamily
ETA57_RS19950	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ETA57_RS19955	COG1950	PFAM Membrane protein of
ETA57_RS19960	COG1983	PspC domain protein
ETA57_RS19965	COG3595	metallopeptidase activity
ETA57_RS19985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETA57_RS19990	COG0556	nucleotide-excision repair
ETA57_RS19995	COG4897	Protein conserved in bacteria
ETA57_RS20005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA57_RS20015	COG3409	Peptidoglycan-binding domain 1 protein
ETA57_RS20015	COG0793	Belongs to the peptidase S41A family
ETA57_RS20020	COG0473	3-isopropylmalate dehydrogenase activity
ETA57_RS20025	COG3883	PFAM NLP P60 protein
ETA57_RS20025	COG0791	NLP P60 protein
ETA57_RS20030	COG2177	Part of the ABC transporter FtsEX involved in
ETA57_RS20035	COG2884	Cell division ATP-binding protein ftsE
ETA57_RS20045	COG2010	Cytochrome c
ETA57_RS20050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS20060	COG0653	protein targeting
ETA57_RS20065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETA57_RS20080	COG1516	flagellar protein fliS
ETA57_RS20085	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETA57_RS20090	COG1334	flagellar protein FlaG
ETA57_RS20095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETA57_RS20100	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETA57_RS20105	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETA57_RS20115	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ETA57_RS20120	COG1256	bacterial-type flagellum assembly
ETA57_RS20120	COG4786	Flagellar basal body rod
ETA57_RS20125	COG3418	PFAM FlgN family protein
ETA57_RS20130	COG2747	anti-sigma28 factor FlgM
ETA57_RS20140	COG1040	competence protein
ETA57_RS20150	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETA57_RS20155	COG1307	EDD domain protein, DegV family
ETA57_RS20160	COG2197	response regulator
ETA57_RS20165	COG4585	Histidine kinase
ETA57_RS20170	COG1739	Uncharacterized protein family UPF0029
ETA57_RS20175	COG1316	TRANSCRIPTIONal
ETA57_RS20185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETA57_RS20190	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS20195	COG1215	transferase activity, transferring glycosyl groups
ETA57_RS20200	COG3206	protein involved in exopolysaccharide biosynthesis
ETA57_RS20205	COG3307	-O-antigen
ETA57_RS20210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETA57_RS20215	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ETA57_RS20220	COG0297	glycogen (starch) synthase activity
ETA57_RS20220	COG0438	transferase activity, transferring glycosyl groups
ETA57_RS20225	COG2244	polysaccharide biosynthetic process
ETA57_RS20235	COG2247	cell wall binding repeat
ETA57_RS20235	COG0860	N-Acetylmuramoyl-L-alanine amidase
ETA57_RS20240	COG2247	cell wall binding repeat
ETA57_RS20240	COG2385	sporulation resulting in formation of a cellular spore
ETA57_RS20250	COG1316	TRANSCRIPTIONal
ETA57_RS20260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ETA57_RS20265	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETA57_RS20270	COG1134	teichoic acid transport
ETA57_RS20275	COG1682	transport, permease protein
ETA57_RS20290	COG0463	Glycosyl transferase, family 2
ETA57_RS20290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA57_RS20295	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA57_RS20300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ETA57_RS20305	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ETA57_RS20310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ETA57_RS20320	COG1482	cell wall glycoprotein biosynthetic process
ETA57_RS20345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA57_RS20350	COG1609	Transcriptional regulator
ETA57_RS20355	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ETA57_RS20360	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS20365	COG1063	alcohol dehydrogenase
ETA57_RS20370	COG2814	Major facilitator Superfamily
ETA57_RS20375	COG1316	TRANSCRIPTIONal
ETA57_RS20380	COG0561	phosphatase activity
ETA57_RS20385	COG0791	NLP P60 protein
ETA57_RS20390	COG2843	Capsule synthesis protein
ETA57_RS20400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETA57_RS20405	COG1609	Transcriptional regulator
ETA57_RS20410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA57_RS20415	COG1869	D-ribose catabolic process
ETA57_RS20420	COG1129	ABC transporter
ETA57_RS20425	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETA57_RS20430	COG1879	ABC-type sugar transport system periplasmic component
ETA57_RS20440	COG3527	Alpha-acetolactate decarboxylase
ETA57_RS20445	COG0028	Belongs to the TPP enzyme family
ETA57_RS20450	COG0583	DNA-binding transcription factor activity
ETA57_RS20460	COG0405	Gamma-glutamyltransferase
ETA57_RS20465	COG1522	sequence-specific DNA binding
ETA57_RS20470	COG2059	Chromate
ETA57_RS20475	COG2059	Chromate
ETA57_RS20480	COG4464	protein tyrosine phosphatase activity
ETA57_RS20485	COG3944	biosynthesis protein
ETA57_RS20495	COG4715	Zinc finger, swim domain protein
ETA57_RS20500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETA57_RS20505	COG0561	phosphatase activity
ETA57_RS20510	COG1349	DNA-binding transcription factor activity
ETA57_RS20520	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS20530	COG3732	PTS system glucitol sorbitol-specific
ETA57_RS20550	COG0629	single-stranded DNA binding
ETA57_RS20565	COG1970	mechanosensitive ion channel activity
ETA57_RS20570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETA57_RS20575	COG4786	Flagellar basal body rod
ETA57_RS20580	COG4786	Flagellar basal body rod
ETA57_RS20585	COG1077	Cell shape determining protein MreB Mrl
ETA57_RS20590	COG1609	Transcriptional regulator
ETA57_RS20600	COG1846	Transcriptional regulator
ETA57_RS20605	COG2814	Major facilitator Superfamily
ETA57_RS20610	COG0671	phosphoesterase, PA-phosphatase related
ETA57_RS20615	COG1227	inorganic diphosphatase activity
ETA57_RS20625	COG3361	conserved protein (COG2071)
ETA57_RS20630	COG0517	IMP dehydrogenase activity
ETA57_RS20635	COG0598	Magnesium transport protein CorA
ETA57_RS20640	COG1253	flavin adenine dinucleotide binding
ETA57_RS20645	COG0004	ammonium transporteR
ETA57_RS20650	COG0347	Belongs to the P(II) protein family
ETA57_RS20655	COG0740	serine-type endopeptidase activity
ETA57_RS20665	COG0739	heme binding
ETA57_RS20670	COG1247	-acetyltransferase
ETA57_RS20680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETA57_RS20685	COG0477	Major facilitator Superfamily
ETA57_RS20690	COG3251	PFAM MbtH domain protein
ETA57_RS20695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA57_RS20700	COG3433	isochorismatase activity
ETA57_RS20700	COG1535	isochorismatase
ETA57_RS20705	COG1021	2,3-dihydroxybenzoate-AMP ligase
ETA57_RS20710	COG1169	isochorismate synthase
ETA57_RS20715	COG1028	Short-chain dehydrogenase reductase Sdr
ETA57_RS20720	COG2819	hydrolase of the alpha beta superfamily
ETA57_RS20725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS20730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETA57_RS20735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS20740	COG2207	Transcriptional regulator
ETA57_RS20740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS20755	COG2910	NAD(P)H-binding
ETA57_RS20760	COG1959	2 iron, 2 sulfur cluster binding
ETA57_RS20770	COG1994	Peptidase M50
ETA57_RS20775	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETA57_RS20780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ETA57_RS20785	COG2223	nitrite transmembrane transporter activity
ETA57_RS20790	COG3383	formate dehydrogenase (NAD+) activity
ETA57_RS20795	COG2304	oxidoreductase activity
ETA57_RS20800	COG2304	oxidoreductase activity
ETA57_RS20805	COG2385	sporulation resulting in formation of a cellular spore
ETA57_RS20810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETA57_RS20820	COG4836	Membrane
ETA57_RS20825	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETA57_RS20830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETA57_RS20835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETA57_RS20840	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETA57_RS20845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETA57_RS20850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ETA57_RS20855	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETA57_RS20875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETA57_RS20880	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETA57_RS20885	COG4475	Protein of unknown function (DUF436)
ETA57_RS20890	COG0698	ribose 5-phosphate isomerase
ETA57_RS20895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETA57_RS20900	COG1971	Probably functions as a manganese efflux pump
ETA57_RS20905	COG0009	L-threonylcarbamoyladenylate synthase
ETA57_RS20910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ETA57_RS20930	COG0561	phosphatase activity
ETA57_RS20935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ETA57_RS20940	COG1609	Transcriptional regulator
ETA57_RS20945	COG2890	protein-(glutamine-N5) methyltransferase activity
ETA57_RS20950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETA57_RS20955	COG0346	lactoylglutathione lyase activity
ETA57_RS20960	COG0789	Transcriptional regulator
ETA57_RS20965	COG0679	Auxin Efflux Carrier
ETA57_RS20970	COG0281	malic enzyme
ETA57_RS20975	COG1435	thymidine kinase activity
ETA57_RS20980	COG0254	rRNA binding
ETA57_RS20985	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETA57_RS20990	COG1494	fructose-1,6-bisphosphatase
ETA57_RS20995	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ETA57_RS21000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETA57_RS21005	COG0191	fructose-bisphosphate aldolase activity
ETA57_RS21010	COG2204	response regulator
ETA57_RS21015	COG4821	SIS domain
ETA57_RS21025	COG0504	CTP synthase activity
ETA57_RS21030	COG3343	RNA polymerase activity
ETA57_RS21035	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS21040	COG1960	acyl-CoA dehydrogenase activity
ETA57_RS21045	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETA57_RS21050	COG0183	Belongs to the thiolase family
ETA57_RS21055	COG2181	nitrate reductase activity
ETA57_RS21055	COG0247	lactate metabolic process
ETA57_RS21060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETA57_RS21070	COG0018	arginyl-trna synthetase
ETA57_RS21075	COG4506	Protein conserved in bacteria
ETA57_RS21080	COG0010	Belongs to the arginase family
ETA57_RS21085	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETA57_RS21110	COG1994	Peptidase M50
ETA57_RS21115	COG1942	4-Oxalocrotonate Tautomerase
ETA57_RS21125	COG3465	dGTPase activity
ETA57_RS21130	COG1078	dGTPase activity
ETA57_RS21135	COG4844	belongs to the
ETA57_RS21160	COG2814	Major facilitator Superfamily
ETA57_RS21185	COG1414	Transcriptional regulator
ETA57_RS21195	COG0280	phosphate acetyltransferase
ETA57_RS21200	COG3253	May function as heme-dependent peroxidase
ETA57_RS21215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETA57_RS21235	COG1131	(ABC) transporter
ETA57_RS21250	COG2363	Small membrane protein
ETA57_RS21255	COG2233	PERMEase
ETA57_RS21265	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS21270	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ETA57_RS21275	COG1216	Glycosyl transferase, family 2
ETA57_RS21280	COG0351	phosphomethylpyrimidine kinase
ETA57_RS21290	COG1621	beta-fructofuranosidase activity
ETA57_RS21295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS21295	COG1263	PTS System
ETA57_RS21300	COG3711	transcriptional antiterminator
ETA57_RS21310	COG1404	Belongs to the peptidase S8 family
ETA57_RS21320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETA57_RS21325	COG0778	Nitroreductase
ETA57_RS21330	COG1473	amidohydrolase
ETA57_RS21340	COG0772	Belongs to the SEDS family
ETA57_RS21345	COG0772	Belongs to the SEDS family
ETA57_RS21350	COG3314	Sporulation integral membrane protein YlbJ
ETA57_RS21370	COG0456	acetyltransferase
ETA57_RS21405	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ETA57_RS21415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETA57_RS21420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETA57_RS21425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETA57_RS21445	COG3162	membrane
ETA57_RS21450	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA57_RS21455	COG1070	Carbohydrate kinase
ETA57_RS21460	COG2115	Belongs to the xylose isomerase family
ETA57_RS21470	COG0352	thiamine-phosphate diphosphorylase activity
ETA57_RS21475	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ETA57_RS21480	COG0583	DNA-binding transcription factor activity
ETA57_RS21495	COG1380	Effector of murein hydrolase LrgA
ETA57_RS21500	COG1346	cytolysis
ETA57_RS21510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETA57_RS21515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETA57_RS21520	COG0346	lactoylglutathione lyase activity
ETA57_RS21525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETA57_RS21530	COG1442	glycosyl transferase family 8
ETA57_RS21540	COG4585	Histidine kinase
ETA57_RS21545	COG2197	response regulator
ETA57_RS21550	COG2409	Drug exporters of the RND superfamily
ETA57_RS21555	COG5522	Integral membrane protein (intg_mem_TP0381)
ETA57_RS21560	COG2271	Major facilitator Superfamily
ETA57_RS21565	COG4948	Mandelate Racemase Muconate Lactonizing
ETA57_RS21570	COG0800	Aldolase
ETA57_RS21575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA57_RS21585	COG2234	aminopeptidase activity
ETA57_RS21590	COG0477	Major facilitator Superfamily
ETA57_RS21600	COG2357	RelA SpoT domain protein
ETA57_RS21615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETA57_RS21620	COG1696	Membrane protein involved in D-alanine export
ETA57_RS21625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETA57_RS21630	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETA57_RS21635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETA57_RS21640	COG2814	Major facilitator Superfamily
ETA57_RS21645	COG1486	melibiose metabolic process
ETA57_RS21650	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETA57_RS21655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS21660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS21670	COG2094	Belongs to the DNA glycosylase MPG family
ETA57_RS21680	COG0372	Belongs to the citrate synthase family
ETA57_RS21685	COG2079	MmgE PrpD family protein
ETA57_RS21690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETA57_RS21705	COG1132	(ABC) transporter
ETA57_RS21710	COG2755	lipolytic protein G-D-S-L family
ETA57_RS21725	COG2814	Major facilitator Superfamily
ETA57_RS21730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA57_RS21735	COG1131	(ABC) transporter
ETA57_RS21755	COG1595	DNA-templated transcription, initiation
ETA57_RS21760	COG2814	Major facilitator Superfamily
ETA57_RS21765	COG0753	catalase activity
ETA57_RS21770	COG0753	catalase activity
ETA57_RS21775	COG0735	belongs to the Fur family
ETA57_RS21780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETA57_RS21785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ETA57_RS21790	COG1131	(ABC) transporter
ETA57_RS21805	COG1131	(ABC) transporter
ETA57_RS21860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETA57_RS21865	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ETA57_RS21870	COG4988	ABC transporter
ETA57_RS21875	COG1294	oxidase, subunit
ETA57_RS21880	COG1271	oxidase subunit
ETA57_RS21890	COG2116	formate transmembrane transporter activity
ETA57_RS21900	COG0281	malic enzyme
ETA57_RS21905	COG1757	Na H antiporter
ETA57_RS21910	COG1027	Aspartate ammonia-lyase
ETA57_RS21915	COG0252	asparaginase activity
ETA57_RS21920	COG1396	sequence-specific DNA binding
ETA57_RS21925	COG2706	6-phosphogluconolactonase activity
ETA57_RS21930	COG0745	RESPONSE REGULATOR receiver
ETA57_RS21935	COG2205	protein histidine kinase activity
ETA57_RS21945	COG1136	(ABC) transporter
ETA57_RS21950	COG0577	efflux transmembrane transporter activity
ETA57_RS21955	COG5294	Protein conserved in bacteria
ETA57_RS21970	COG0726	polysaccharide deacetylase
ETA57_RS21975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETA57_RS21985	COG1215	transferase activity, transferring glycosyl groups
ETA57_RS21990	COG3493	citrate carrier protein
ETA57_RS21995	COG0584	glycerophosphoryl diester phosphodiesterase
ETA57_RS22010	COG1368	sulfuric ester hydrolase activity
ETA57_RS22020	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETA57_RS22035	COG2235	arginine
ETA57_RS22040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETA57_RS22050	COG0549	Belongs to the carbamate kinase family
ETA57_RS22065	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETA57_RS22075	COG1595	DNA-templated transcription, initiation
ETA57_RS22100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETA57_RS22105	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETA57_RS22115	COG1621	beta-fructofuranosidase activity
ETA57_RS22120	COG2223	nitrite transmembrane transporter activity
ETA57_RS22125	COG1609	Transcriptional regulator
ETA57_RS22140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ETA57_RS22145	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETA57_RS22150	COG0463	Glycosyl transferase, family 2
ETA57_RS22155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETA57_RS22180	COG1122	ATPase activity
ETA57_RS22185	COG4721	ABC-type cobalt transport system, permease component
ETA57_RS22190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ETA57_RS22195	COG2224	Isocitrate lyase
ETA57_RS22200	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ETA57_RS22210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ETA57_RS22215	COG0577	efflux transmembrane transporter activity
ETA57_RS22220	COG1136	(ABC) transporter
ETA57_RS22225	COG2205	protein histidine kinase activity
ETA57_RS22230	COG0745	RESPONSE REGULATOR receiver
ETA57_RS22235	COG2723	6-phospho-beta-galactosidase activity
ETA57_RS22240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS22240	COG2190	(PTS) system
ETA57_RS22240	COG1263	PTS System
ETA57_RS22250	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ETA57_RS22255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETA57_RS22260	COG3507	Belongs to the glycosyl hydrolase 43 family
ETA57_RS22265	COG0513	Belongs to the DEAD box helicase family
ETA57_RS22295	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETA57_RS22300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETA57_RS22305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETA57_RS22310	COG2390	Transcriptional regulator
ETA57_RS22320	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ETA57_RS22325	COG3706	GGDEF domain
ETA57_RS22335	COG1215	transferase activity, transferring glycosyl groups
ETA57_RS22345	COG3977	Valine--pyruvate aminotransferase
ETA57_RS22360	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETA57_RS22370	COG0191	fructose-bisphosphate aldolase activity
ETA57_RS22375	COG1082	Xylose isomerase domain protein TIM barrel
ETA57_RS22380	COG1082	Xylose isomerase domain protein TIM barrel
ETA57_RS22385	COG0673	inositol 2-dehydrogenase activity
ETA57_RS22390	COG2814	Major facilitator Superfamily
ETA57_RS22395	COG1082	Xylose isomerase domain protein TIM barrel
ETA57_RS22400	COG3962	Belongs to the TPP enzyme family
ETA57_RS22405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETA57_RS22410	COG3718	enzyme involved in inositol metabolism
ETA57_RS22415	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS22420	COG1349	DNA-binding transcription factor activity
ETA57_RS22425	COG0667	Aldo Keto reductase
ETA57_RS22430	COG0584	glycerophosphoryl diester phosphodiesterase
ETA57_RS22435	COG2271	Major facilitator Superfamily
ETA57_RS22445	COG0326	Molecular chaperone. Has ATPase activity
ETA57_RS22450	COG0488	(ABC) transporter
ETA57_RS22455	COG0561	phosphatase activity
ETA57_RS22475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETA57_RS22505	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ETA57_RS22515	COG0577	efflux transmembrane transporter activity
ETA57_RS22520	COG1136	(ABC) transporter
ETA57_RS22525	COG2205	protein histidine kinase activity
ETA57_RS22530	COG0745	RESPONSE REGULATOR receiver
ETA57_RS22540	COG0840	transmembrane signaling receptor activity
ETA57_RS22540	COG5278	phosphoserine phosphatase activity
ETA57_RS22545	COG1115	amino acid carrier protein
ETA57_RS22550	COG0686	Belongs to the AlaDH PNT family
ETA57_RS22555	COG3867	Arabinogalactan endo-beta-1,4-galactanase
ETA57_RS22560	COG1874	Beta-galactosidase
ETA57_RS22565	COG3833	ABC-type maltose transport systems, permease component
ETA57_RS22570	COG1175	transmembrane transport
ETA57_RS22575	COG2182	Extracellular solute-binding protein
ETA57_RS22580	COG1609	Transcriptional regulator
ETA57_RS22590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETA57_RS22600	COG1940	carbohydrate kinase activity
ETA57_RS22625	COG1012	belongs to the aldehyde dehydrogenase family
ETA57_RS22625	COG1454	alcohol dehydrogenase
ETA57_RS22630	COG0450	alkyl hydroperoxide reductase
ETA57_RS22635	COG3634	alkyl hydroperoxide reductase activity
ETA57_RS22660	COG1131	(ABC) transporter
ETA57_RS22665	COG0842	Transport permease protein
ETA57_RS22675	COG2197	response regulator
ETA57_RS22715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ETA57_RS22720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ETA57_RS22735	COG0456	acetyltransferase
ETA57_RS22750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETA57_RS22755	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETA57_RS22760	COG4853	Protein conserved in bacteria
ETA57_RS22765	COG4863	YycH protein
ETA57_RS22770	COG5002	protein histidine kinase activity
ETA57_RS22775	COG0745	RESPONSE REGULATOR receiver
ETA57_RS22800	COG1051	belongs to the nudix hydrolase family
ETA57_RS22805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ETA57_RS22815	COG0305	Participates in initiation and elongation during chromosome replication
ETA57_RS22830	COG3093	addiction module antidote protein HigA
ETA57_RS22835	COG2807	transmembrane transport
ETA57_RS22840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETA57_RS22845	COG0363	glucosamine-6-phosphate deaminase activity
ETA57_RS22850	COG2188	Transcriptional regulator
ETA57_RS22855	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ETA57_RS22860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETA57_RS22860	COG1263	PTS System
ETA57_RS22865	COG0359	binds to the 23S rRNA
ETA57_RS22870	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ETA57_RS22875	COG4241	membrane
ETA57_RS22880	COG5577	PFAM Coat F domain
ETA57_RS22885	COG0589	response to stress
ETA57_RS22890	COG0659	secondary active sulfate transmembrane transporter activity
ETA57_RS22895	COG2271	Major facilitator Superfamily
ETA57_RS22900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETA57_RS22905	COG0629	single-stranded DNA binding
ETA57_RS22910	COG0360	Binds together with S18 to 16S ribosomal RNA
ETA57_RS22915	COG0012	GTP binding
ETA57_RS22925	COG4481	Protein conserved in bacteria
ETA57_RS22930	COG3949	Membrane
ETA57_RS22940	COG1475	DNA binding
ETA57_RS22945	COG1192	Involved in chromosome partitioning
ETA57_RS22950	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ETA57_RS22960	COG1475	DNA binding
ETA57_RS22965	COG0357	Ribosomal RNA small subunit methyltransferase G
ETA57_RS22970	COG0445	tRNA wobble uridine modification
ETA57_RS22975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETA57_RS22980	COG1847	R3H domain protein
ETA57_RS22985	COG0706	membrane insertase activity
ETA57_RS22990	COG0594	ribonuclease P activity