locus-tag	class	description
C7M53_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7M53_RS00010	COG0592	DNA-directed DNA polymerase activity
C7M53_RS00015	COG2501	S4 domain
C7M53_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7M53_RS00030	COG0187	DNA topoisomerase II activity
C7M53_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M53_RS00070	COG0517	IMP dehydrogenase activity
C7M53_RS00070	COG0516	GMP reductase activity
C7M53_RS00075	COG1686	Belongs to the peptidase S11 family
C7M53_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
C7M53_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
C7M53_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7M53_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
C7M53_RS00100	COG2610	gluconate transmembrane transporter activity
C7M53_RS00105	COG3835	regulator
C7M53_RS00120	COG1428	Deoxynucleoside kinase
C7M53_RS00125	COG1428	Deoxynucleoside kinase
C7M53_RS00130	COG3858	chitin binding
C7M53_RS00130	COG1388	LysM domain
C7M53_RS00135	COG1335	isochorismatase
C7M53_RS00140	COG0590	tRNA wobble adenosine to inosine editing
C7M53_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7M53_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7M53_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7M53_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
C7M53_RS00210	COG3853	Toxic anion resistance protein (TelA)
C7M53_RS00215	COG1982	Orn Lys Arg decarboxylase major
C7M53_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7M53_RS00225	COG3870	Protein conserved in bacteria
C7M53_RS00230	COG1728	Protein conserved in bacteria
C7M53_RS00235	COG0470	DNA polymerase III
C7M53_RS00240	COG1774	PSP1 C-terminal conserved region
C7M53_RS00245	COG4467	Involved in initiation control of chromosome replication
C7M53_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7M53_RS00255	COG2827	Endonuclease containing a URI domain
C7M53_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7M53_RS00265	COG2002	toxin-antitoxin pair type II binding
C7M53_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_RS00275	COG0084	hydrolase, TatD family'
C7M53_RS00280	COG3583	domain protein
C7M53_RS00280	COG3584	3D domain protein
C7M53_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M53_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7M53_RS00300	COG4466	Protein conserved in bacteria
C7M53_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7M53_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_RS00320	COG0251	oxidation-reduction process
C7M53_RS00325	COG2088	sporulation resulting in formation of a cellular spore
C7M53_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7M53_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7M53_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7M53_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
C7M53_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7M53_RS00360	COG2002	toxin-antitoxin pair type II binding
C7M53_RS00365	COG2244	polysaccharide biosynthetic process
C7M53_RS00370	COG3956	TIGRFAM MazG family protein
C7M53_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7M53_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7M53_RS00395	COG1098	S1 RNA binding domain
C7M53_RS00410	COG2208	phosphoserine phosphatase activity
C7M53_RS00415	COG2304	oxidoreductase activity
C7M53_RS00420	COG0515	serine threonine protein kinase
C7M53_RS00425	COG0037	tRNA processing
C7M53_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
C7M53_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7M53_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C7M53_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7M53_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M53_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M53_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
C7M53_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7M53_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7M53_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7M53_RS00495	COG1396	sequence-specific DNA binding
C7M53_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7M53_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7M53_RS00535	COG4463	regulation of RNA biosynthetic process
C7M53_RS00540	COG3880	PFAM UvrB UvrC protein
C7M53_RS00545	COG3869	Catalyzes the specific phosphorylation of arginine residues in
C7M53_RS00550	COG0542	response to heat
C7M53_RS00555	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7M53_RS00560	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
C7M53_RS00565	COG4956	integral membrane protein (PIN domain superfamily)
C7M53_RS00570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7M53_RS00575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7M53_RS00580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7M53_RS00585	COG1045	serine acetyltransferase
C7M53_RS00590	COG0215	cysteine-tRNA ligase activity
C7M53_RS00595	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7M53_RS00600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M53_RS00605	COG3688	RNA-binding protein containing a PIN domain
C7M53_RS00615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_RS00625	COG0250	Participates in transcription elongation, termination and antitermination
C7M53_RS00630	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7M53_RS00635	COG0081	regulation of translation
C7M53_RS00640	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7M53_RS00645	COG0222	ribosome binding
C7M53_RS00650	COG2813	Specifically methylates the guanine in position
C7M53_RS00655	COG0085	RNA polymerase activity
C7M53_RS00660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7M53_RS00665	COG1358	cellular component organization or biogenesis
C7M53_RS00670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7M53_RS00675	COG0049	tRNA binding
C7M53_RS00680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7M53_RS00685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7M53_RS00695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7M53_RS00700	COG0088	Forms part of the polypeptide exit tunnel
C7M53_RS00705	COG0089	rRNA binding
C7M53_RS00710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7M53_RS00715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7M53_RS00720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7M53_RS00725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7M53_RS00730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7M53_RS00735	COG0255	Belongs to the universal ribosomal protein uL29 family
C7M53_RS00740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7M53_RS00745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7M53_RS00750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7M53_RS00755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7M53_RS00760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_RS00765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7M53_RS00770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7M53_RS00775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7M53_RS00780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7M53_RS00785	COG1841	ribosomal large subunit assembly
C7M53_RS00790	COG0200	Binds to the 23S rRNA
C7M53_RS00795	COG0201	protein transport
C7M53_RS00800	COG0563	adenylate kinase activity
C7M53_RS00805	COG0024	Methionine aminopeptidase
C7M53_RS00810	COG2163	COG2163 Ribosomal protein L14E L6E L27E
C7M53_RS00815	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7M53_RS00820	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7M53_RS00825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7M53_RS00830	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7M53_RS00835	COG0202	RNA polymerase activity
C7M53_RS00840	COG0203	ribosomal protein L17
C7M53_RS00845	COG1122	ATPase activity
C7M53_RS00850	COG1122	ATPase activity
C7M53_RS00855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M53_RS00860	COG0101	tRNA pseudouridine synthase activity
C7M53_RS00865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7M53_RS00870	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7M53_RS00875	COG2318	DinB family
C7M53_RS00885	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS00890	COG0489	protein tyrosine kinase activity
C7M53_RS00900	COG2194	sulfuric ester hydrolase activity
C7M53_RS00905	COG0726	polysaccharide deacetylase
C7M53_RS00935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_RS00945	COG0385	Bile acid
C7M53_RS00960	COG3876	Protein conserved in bacteria
C7M53_RS00965	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M53_RS00970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_RS00975	COG1263	PTS System
C7M53_RS00975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS00980	COG1737	Transcriptional regulator
C7M53_RS00985	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M53_RS00990	COG1683	Conserved Protein
C7M53_RS01025	COG1595	DNA-templated transcription, initiation
C7M53_RS01030	COG5662	AntiSigma factor
C7M53_RS01035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7M53_RS01040	COG4856	YbbR-like protein
C7M53_RS01045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M53_RS01050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7M53_RS01070	COG1725	Transcriptional regulator
C7M53_RS01075	COG0640	Transcriptional regulator
C7M53_RS01080	COG2814	Major facilitator Superfamily
C7M53_RS01090	COG1132	(ABC) transporter
C7M53_RS01095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M53_RS01120	COG1011	Hydrolase
C7M53_RS01125	COG1113	amino acid transport
C7M53_RS01130	COG2851	Citrate transporter
C7M53_RS01135	COG3181	Tripartite tricarboxylate transporter family receptor
C7M53_RS01140	COG4565	transcriptional regulatory protein
C7M53_RS01145	COG3290	protein histidine kinase activity
C7M53_RS01160	COG2211	Major facilitator Superfamily
C7M53_RS01180	COG1331	Highly conserved protein containing a thioredoxin domain
C7M53_RS01190	COG0477	Major facilitator Superfamily
C7M53_RS01210	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M53_RS01215	COG4682	membrane
C7M53_RS01245	COG1917	Cupin 2, conserved barrel domain protein
C7M53_RS01245	COG2207	Transcriptional regulator
C7M53_RS01265	COG0371	Dehydrogenase
C7M53_RS01270	COG0840	transmembrane signaling receptor activity
C7M53_RS01275	COG4213	ABC transporter substrate-binding protein
C7M53_RS01290	COG4257	antibiotic catabolic process
C7M53_RS01300	COG0833	amino acid
C7M53_RS01305	COG2040	homocysteine
C7M53_RS01315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS01315	COG1263	PTS System
C7M53_RS01315	COG2190	(PTS) system
C7M53_RS01320	COG0789	Transcriptional regulator
C7M53_RS01325	COG2323	membrane
C7M53_RS01330	COG4451	ribulose bisphosphate carboxylase, small
C7M53_RS01330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M53_RS01340	COG2205	protein histidine kinase activity
C7M53_RS01345	COG1115	amino acid carrier protein
C7M53_RS01350	COG2066	Belongs to the glutaminase family
C7M53_RS01355	COG4191	Histidine kinase
C7M53_RS01360	COG0784	Response regulator, receiver
C7M53_RS01385	COG3540	Alkaline phosphatase
C7M53_RS01390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M53_RS01395	COG0805	protein transport
C7M53_RS01400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS01410	COG2271	Major facilitator Superfamily
C7M53_RS01415	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_RS01420	COG2186	Transcriptional regulator
C7M53_RS01425	COG2721	sulfolactate sulfo-lyase activity
C7M53_RS01430	COG0745	RESPONSE REGULATOR receiver
C7M53_RS01435	COG2205	protein histidine kinase activity
C7M53_RS01465	COG3173	Aminoglycoside phosphotransferase
C7M53_RS01470	COG1846	Transcriptional regulator
C7M53_RS01475	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS01500	COG0789	Transcriptional regulator
C7M53_RS01525	COG0697	spore germination
C7M53_RS01530	COG1714	RDD family
C7M53_RS01535	COG3012	SEC-C Motif Domain Protein
C7M53_RS01535	COG1405	negative regulation of cell septum assembly
C7M53_RS01540	COG1131	(ABC) transporter
C7M53_RS01565	COG0583	DNA-binding transcription factor activity
C7M53_RS01570	COG1942	4-Oxalocrotonate Tautomerase
C7M53_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS01590	COG1288	antiporter activity
C7M53_RS01600	COG0456	acetyltransferase
C7M53_RS01610	COG1164	Oligoendopeptidase f
C7M53_RS01615	COG2261	transglycosylase associated protein
C7M53_RS01625	COG0247	lactate metabolic process
C7M53_RS01630	COG0277	FAD linked oxidase domain protein
C7M53_RS01635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS01640	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_RS01645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS01650	COG1486	melibiose metabolic process
C7M53_RS01655	COG2188	Transcriptional regulator
C7M53_RS01660	COG3394	polysaccharide catabolic process
C7M53_RS01675	COG3591	Belongs to the peptidase S1B family
C7M53_RS01680	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS01690	COG1595	DNA-templated transcription, initiation
C7M53_RS01700	COG3773	Cell wall hydrolase
C7M53_RS01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_RS01710	COG3883	PFAM NLP P60 protein
C7M53_RS01710	COG0791	NLP P60 protein
C7M53_RS01720	COG1131	(ABC) transporter
C7M53_RS01725	COG1309	transcriptional regulator
C7M53_RS01745	COG2310	stress, protein
C7M53_RS01750	COG2310	stress, protein
C7M53_RS01755	COG2310	stress, protein
C7M53_RS01760	COG0861	Integral membrane protein TerC family
C7M53_RS01780	COG3853	Toxic anion resistance protein (TelA)
C7M53_RS01785	COG0785	Cytochrome C biogenesis protein
C7M53_RS01795	COG0789	Transcriptional regulator
C7M53_RS01800	COG2223	nitrite transmembrane transporter activity
C7M53_RS01805	COG0039	L-malate dehydrogenase activity
C7M53_RS01810	COG1620	l-lactate permease
C7M53_RS01815	COG1280	lysine exporter protein (LysE YggA)
C7M53_RS01820	COG1113	amino acid transport
C7M53_RS01825	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7M53_RS01830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7M53_RS01835	COG3541	Predicted nucleotidyltransferase
C7M53_RS01840	COG0506	proline dehydrogenase activity
C7M53_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS01850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS01855	COG2508	Transcriptional regulator
C7M53_RS01860	COG3689	TIGRFAM TIGR03943 family protein
C7M53_RS01865	COG0701	Predicted permease
C7M53_RS01870	COG3458	cephalosporin-C deacetylase activity
C7M53_RS01890	COG0765	amino acid transport
C7M53_RS01895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_RS01900	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS01910	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS01920	COG3209	COG3209 Rhs family protein
C7M53_RS01925	COG0515	serine threonine protein kinase
C7M53_RS01925	COG3266	domain, Protein
C7M53_RS01935	COG5444	nuclease activity
C7M53_RS01960	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7M53_RS01965	COG1177	transmembrane transport
C7M53_RS01970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_RS01975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_RS01980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_RS01985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7M53_RS01990	COG0697	spore germination
C7M53_RS01995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_RS02005	COG2819	hydrolase of the alpha beta superfamily
C7M53_RS02015	COG2364	Membrane
C7M53_RS02025	COG1131	(ABC) transporter
C7M53_RS02050	COG1126	abc transporter atp-binding protein
C7M53_RS02055	COG0765	amino acid transport
C7M53_RS02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_RS02065	COG3829	transcription factor binding
C7M53_RS02070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M53_RS02075	COG0833	amino acid
C7M53_RS02080	COG0010	Belongs to the arginase family
C7M53_RS02085	COG0583	DNA-binding transcription factor activity
C7M53_RS02090	COG0163	prenyltransferase activity
C7M53_RS02095	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7M53_RS02145	COG5444	nuclease activity
C7M53_RS02165	COG2972	Histidine kinase
C7M53_RS02170	COG2207	Transcriptional regulator
C7M53_RS02170	COG4753	response regulator
C7M53_RS02175	COG4213	ABC transporter substrate-binding protein
C7M53_RS02185	COG4214	carbohydrate transport
C7M53_RS02190	COG2271	Major facilitator Superfamily
C7M53_RS02195	COG1846	Transcriptional regulator
C7M53_RS02195	COG0456	acetyltransferase
C7M53_RS02200	COG1874	Beta-galactosidase
C7M53_RS02205	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
C7M53_RS02210	COG3104	oligopeptide transport
C7M53_RS02215	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M53_RS02225	COG0697	spore germination
C7M53_RS02235	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7M53_RS02240	COG0789	Transcriptional regulator
C7M53_RS02245	COG1136	(ABC) transporter
C7M53_RS02250	COG0577	efflux transmembrane transporter activity
C7M53_RS02255	COG0745	RESPONSE REGULATOR receiver
C7M53_RS02260	COG5002	protein histidine kinase activity
C7M53_RS02260	COG3850	Histidine kinase
C7M53_RS02265	COG0840	transmembrane signaling receptor activity
C7M53_RS02270	COG0527	aspartate kinase activity
C7M53_RS02275	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS02280	COG4605	iron ion homeostasis
C7M53_RS02285	COG4604	ABC transporter, ATP-binding protein
C7M53_RS02290	COG4607	ABC-type enterochelin transport system periplasmic component
C7M53_RS02295	COG2814	Major facilitator Superfamily
C7M53_RS02300	COG1309	transcriptional regulator
C7M53_RS02310	COG0778	Nitroreductase
C7M53_RS02315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M53_RS02320	COG0640	Transcriptional regulator
C7M53_RS02325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_RS02330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7M53_RS02335	COG0531	amino acid
C7M53_RS02340	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS02345	COG0697	spore germination
C7M53_RS02355	COG4549	nuclear export factor GLE1
C7M53_RS02360	COG2372	response to copper ion
C7M53_RS02360	COG1276	copper resistance
C7M53_RS02365	COG1349	DNA-binding transcription factor activity
C7M53_RS02370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_RS02375	COG0243	molybdopterin cofactor binding
C7M53_RS02380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_RS02385	COG2146	nitrite reductase [NAD(P)H] activity
C7M53_RS02390	COG1587	Uroporphyrinogen-III synthase
C7M53_RS02390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M53_RS02395	COG1802	Transcriptional regulator
C7M53_RS02400	COG0471	metal ion transport
C7M53_RS02405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_RS02410	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_RS02425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS02440	COG3959	Transketolase, thiamine diphosphate binding domain
C7M53_RS02445	COG3958	Transketolase
C7M53_RS02450	COG0561	phosphatase activity
C7M53_RS02455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7M53_RS02460	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M53_RS02465	COG4336	lyase activity
C7M53_RS02470	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7M53_RS02475	COG1984	allophanate hydrolase subunit 2
C7M53_RS02480	COG1414	Transcriptional regulator
C7M53_RS02485	COG2755	lipolytic protein G-D-S-L family
C7M53_RS02490	COG2213	PTS system mannitol-specific
C7M53_RS02495	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS02500	COG0246	Mannitol dehydrogenase
C7M53_RS02505	COG3711	transcriptional antiterminator
C7M53_RS02510	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS02515	COG1917	Cupin 2, conserved barrel domain protein
C7M53_RS02525	COG3871	stress protein (general stress protein 26)
C7M53_RS02540	COG2814	Major facilitator Superfamily
C7M53_RS02550	COG1522	sequence-specific DNA binding
C7M53_RS02555	COG0551	DNA topoisomerase type I activity
C7M53_RS02555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M53_RS02560	COG0531	amino acid
C7M53_RS02565	COG0028	Belongs to the TPP enzyme family
C7M53_RS02570	COG3397	chitin binding
C7M53_RS02585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS02590	COG1914	H( )-stimulated, divalent metal cation uptake system
C7M53_RS02595	COG2261	transglycosylase associated protein
C7M53_RS02600	COG1027	Aspartate ammonia-lyase
C7M53_RS02610	COG4876	unkown
C7M53_RS02615	COG2217	Heavy metal translocating P-type atpase
C7M53_RS02625	COG0662	Cupin 2, conserved barrel domain protein
C7M53_RS02630	COG3729	General stress protein
C7M53_RS02635	COG0628	permease
C7M53_RS02640	COG1301	dicarboxylic acid transport
C7M53_RS02645	COG1131	(ABC) transporter
C7M53_RS02650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_RS02660	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS02675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS02680	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M53_RS02685	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7M53_RS02695	COG0513	Belongs to the DEAD box helicase family
C7M53_RS02700	COG3402	PFAM membrane-flanked domain
C7M53_RS02705	COG3428	Bacterial PH domain
C7M53_RS02710	COG0705	Rhomboid family
C7M53_RS02715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7M53_RS02720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M53_RS02725	COG0864	Transcriptional regulator
C7M53_RS02730	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M53_RS02735	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_RS02740	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_RS02745	COG2172	sigma factor antagonist activity
C7M53_RS02750	COG2208	phosphoserine phosphatase activity
C7M53_RS02760	COG2172	sigma factor antagonist activity
C7M53_RS02765	COG1191	sigma factor activity
C7M53_RS02770	COG2208	phosphoserine phosphatase activity
C7M53_RS02775	COG2183	response to ionizing radiation
C7M53_RS02780	COG1309	transcriptional regulator
C7M53_RS02785	COG2409	Drug exporters of the RND superfamily
C7M53_RS02785	COG1033	growth of symbiont in host cell
C7M53_RS02795	COG3091	SprT-like family
C7M53_RS02840	COG1476	TRANSCRIPTIONal
C7M53_RS02845	COG3239	Fatty acid desaturase
C7M53_RS02850	COG1278	Cold shock
C7M53_RS02855	COG1063	alcohol dehydrogenase
C7M53_RS02865	COG2364	Membrane
C7M53_RS02870	COG1846	Transcriptional regulator
C7M53_RS02875	COG0456	acetyltransferase
C7M53_RS02880	COG2808	Putative FMN-binding domain
C7M53_RS02890	COG1733	regulation of RNA biosynthetic process
C7M53_RS02895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS02905	COG0583	DNA-binding transcription factor activity
C7M53_RS02920	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C7M53_RS02925	COG1113	amino acid transport
C7M53_RS02940	COG1595	DNA-templated transcription, initiation
C7M53_RS02950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C7M53_RS02950	COG2755	lipolytic protein G-D-S-L family
C7M53_RS02955	COG2814	Major facilitator Superfamily
C7M53_RS02960	COG2972	Histidine kinase
C7M53_RS02960	COG0745	RESPONSE REGULATOR receiver
C7M53_RS02965	COG3279	Response regulator of the LytR AlgR family
C7M53_RS02975	COG3764	Sortase (surface protein transpeptidase)
C7M53_RS02980	COG2814	Major facilitator Superfamily
C7M53_RS03080	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7M53_RS03085	COG0802	atpase or kinase
C7M53_RS03090	COG1214	PFAM Peptidase M22, glycoprotease
C7M53_RS03095	COG0456	acetyltransferase
C7M53_RS03100	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7M53_RS03105	COG0488	(ABC) transporter
C7M53_RS03110	COG0315	cyclic pyranopterin monophosphate synthase activity
C7M53_RS03115	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
C7M53_RS03120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7M53_RS03125	COG0805	protein transport
C7M53_RS03135	COG1266	CAAX protease self-immunity
C7M53_RS03140	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7M53_RS03145	COG0459	protein refolding
C7M53_RS03175	COG2720	vancomycin resistance protein
C7M53_RS03190	COG2135	peptidase activity
C7M53_RS03200	COG1309	transcriptional regulator
C7M53_RS03205	COG3848	Pyruvate phosphate dikinase
C7M53_RS03205	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_RS03215	COG3189	MarR family transcriptional regulator
C7M53_RS03220	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
C7M53_RS03225	COG2272	Belongs to the type-B carboxylesterase lipase family
C7M53_RS03230	COG2814	Major facilitator Superfamily
C7M53_RS03235	COG1842	Phage shock protein A
C7M53_RS03240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M53_RS03245	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7M53_RS03250	COG4260	virion core protein, lumpy skin disease virus
C7M53_RS03260	COG1378	Sugar-specific transcriptional regulator TrmB
C7M53_RS03265	COG1280	lysine exporter protein (LysE YggA)
C7M53_RS03270	COG3339	Conserved Protein
C7M53_RS03275	COG0772	Belongs to the SEDS family
C7M53_RS03280	COG0772	Belongs to the SEDS family
C7M53_RS03305	COG0726	polysaccharide deacetylase
C7M53_RS03315	COG1609	Transcriptional regulator
C7M53_RS03320	COG0366	Alpha amylase catalytic
C7M53_RS03325	COG2182	Extracellular solute-binding protein
C7M53_RS03330	COG1175	transmembrane transport
C7M53_RS03335	COG3833	ABC-type maltose transport systems, permease component
C7M53_RS03340	COG5521	maltodextrose utilization protein MalA
C7M53_RS03345	COG1554	hydrolase, family 65, central catalytic
C7M53_RS03350	COG0366	Alpha amylase catalytic
C7M53_RS03355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M53_RS03360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M53_RS03365	COG1846	Transcriptional regulator
C7M53_RS03380	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7M53_RS03385	COG0823	Involved in the tonB-independent uptake of proteins
C7M53_RS03420	COG0702	epimerase
C7M53_RS03430	COG2132	Multicopper oxidase
C7M53_RS03445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7M53_RS03450	COG0714	Associated with various cellular activities
C7M53_RS03455	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
C7M53_RS03460	COG1305	Transglutaminase-like
C7M53_RS03465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7M53_RS03465	COG0519	Catalyzes the synthesis of GMP from XMP
C7M53_RS03475	COG2252	PERMEase
C7M53_RS03490	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
C7M53_RS03500	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7M53_RS03505	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7M53_RS03510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7M53_RS03515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7M53_RS03520	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M53_RS03525	COG0047	phosphoribosylformylglycinamidine synthase activity
C7M53_RS03530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7M53_RS03535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7M53_RS03540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7M53_RS03545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7M53_RS03550	COG0138	bifunctional purine biosynthesis protein purh
C7M53_RS03555	COG0151	Belongs to the GarS family
C7M53_RS03565	COG2124	cytochrome p450
C7M53_RS03585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M53_RS03590	COG1470	cell adhesion involved in biofilm formation
C7M53_RS03595	COG4496	protein, YerC YecD
C7M53_RS03600	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
C7M53_RS03605	COG0210	DNA helicase
C7M53_RS03610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7M53_RS03615	COG4851	CamS sex pheromone cAM373 precursor
C7M53_RS03620	COG2188	Transcriptional regulator
C7M53_RS03640	COG1735	metal-dependent hydrolase with the TIM-barrel fold
C7M53_RS03645	COG0626	cystathionine gamma-synthase activity
C7M53_RS03650	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M53_RS03655	COG3457	Alanine racemase
C7M53_RS03660	COG0363	glucosamine-6-phosphate deaminase activity
C7M53_RS03665	COG1285	pathogenesis
C7M53_RS03670	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS03675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M53_RS03680	COG0154	amidase activity
C7M53_RS03685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7M53_RS03700	COG4124	Belongs to the glycosyl hydrolase 26 family
C7M53_RS03705	COG1309	transcriptional regulator
C7M53_RS03710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7M53_RS03720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS03725	COG1957	nucleoside hydrolase
C7M53_RS03730	COG1597	lipid kinase activity
C7M53_RS03735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M53_RS03745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS03745	COG1263	PTS System
C7M53_RS03745	COG2190	(PTS) system
C7M53_RS03750	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS03755	COG3711	transcriptional antiterminator
C7M53_RS03760	COG0457	Tetratricopeptide repeat
C7M53_RS03780	COG0217	transcriptional regulatory protein
C7M53_RS03795	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS03800	COG0840	transmembrane signaling receptor activity
C7M53_RS03805	COG0471	metal ion transport
C7M53_RS03810	COG0488	(ABC) transporter
C7M53_RS03815	COG1469	GTP cyclohydrolase I activity
C7M53_RS03830	COG0523	cobalamin synthesis protein
C7M53_RS03835	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
C7M53_RS03840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M53_RS03845	COG0156	8-amino-7-oxononanoate synthase activity
C7M53_RS03850	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7M53_RS03855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7M53_RS03860	COG2124	cytochrome p450
C7M53_RS03870	COG0789	Transcriptional regulator
C7M53_RS03875	COG2814	Major facilitator Superfamily
C7M53_RS03880	COG0488	(ABC) transporter
C7M53_RS03885	COG0513	Belongs to the DEAD box helicase family
C7M53_RS03890	COG2130	NADP-dependent
C7M53_RS03905	COG0471	metal ion transport
C7M53_RS03920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS03930	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
C7M53_RS03935	COG5658	integral membrane protein
C7M53_RS03940	COG0640	Transcriptional regulator
C7M53_RS03945	COG1254	Belongs to the acylphosphatase family
C7M53_RS03950	COG2258	MOSC domain
C7M53_RS03960	COG0024	Methionine aminopeptidase
C7M53_RS03965	COG1368	sulfuric ester hydrolase activity
C7M53_RS03980	COG1263	PTS System
C7M53_RS03980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS03985	COG0366	Alpha amylase catalytic
C7M53_RS03990	COG2188	Transcriptional regulator
C7M53_RS04015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_RS04020	COG1045	serine acetyltransferase
C7M53_RS04025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_RS04035	COG1215	transferase activity, transferring glycosyl groups
C7M53_RS04040	COG0463	Glycosyl transferase, family 2
C7M53_RS04040	COG0457	Tetratricopeptide repeat
C7M53_RS04050	COG0673	inositol 2-dehydrogenase activity
C7M53_RS04060	COG0657	acetylesterase activity
C7M53_RS04065	COG1733	regulation of RNA biosynthetic process
C7M53_RS04070	COG0778	Nitroreductase
C7M53_RS04075	COG0737	Belongs to the 5'-nucleotidase family
C7M53_RS04080	COG0693	protein deglycase activity
C7M53_RS04085	COG4840	Belongs to the UPF0435 family
C7M53_RS04090	COG1115	amino acid carrier protein
C7M53_RS04095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_RS04100	COG4980	gas vesicle protein
C7M53_RS04105	COG1295	ribonuclease BN
C7M53_RS04110	COG0477	Major facilitator Superfamily
C7M53_RS04120	COG0387	Pfam Sodium calcium exchanger
C7M53_RS04130	COG0535	radical SAM domain protein
C7M53_RS04140	COG0726	polysaccharide deacetylase
C7M53_RS04145	COG0371	Dehydrogenase
C7M53_RS04155	COG0598	Magnesium transport protein CorA
C7M53_RS04160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7M53_RS04165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7M53_RS04170	COG4637	Psort location Cytoplasmic, score
C7M53_RS04195	COG1819	glycosyl
C7M53_RS04205	COG0477	Major facilitator Superfamily
C7M53_RS04210	COG1263	PTS System
C7M53_RS04210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS04215	COG3711	transcriptional antiterminator
C7M53_RS04220	COG0288	reversible hydration of carbon dioxide
C7M53_RS04225	COG3002	Belongs to the UPF0753 family
C7M53_RS04230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M53_RS04235	COG5609	conserved protein (DUF2294)
C7M53_RS04245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_RS04250	COG0022	dehydrogenase e1 component
C7M53_RS04255	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_RS04260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_RS04265	COG3284	Transcriptional regulator
C7M53_RS04270	COG1742	UPF0060 membrane protein
C7M53_RS04275	COG1486	melibiose metabolic process
C7M53_RS04280	COG1737	Transcriptional regulator
C7M53_RS04285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS04285	COG1263	PTS System
C7M53_RS04300	COG1733	regulation of RNA biosynthetic process
C7M53_RS04305	COG2259	Doxx family
C7M53_RS04310	COG2514	catechol 2,3-dioxygenase activity
C7M53_RS04325	COG2207	Transcriptional regulator
C7M53_RS04325	COG1917	Cupin 2, conserved barrel domain protein
C7M53_RS04330	COG1653	transport
C7M53_RS04335	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS04340	COG1051	belongs to the nudix hydrolase family
C7M53_RS04350	COG0392	lysyltransferase activity
C7M53_RS04350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C7M53_RS04355	COG0384	phenazine biosynthesis protein PhzF
C7M53_RS04360	COG0778	Nitroreductase
C7M53_RS04380	COG1090	epimerase
C7M53_RS04385	COG2137	regulation of response to DNA damage stimulus
C7M53_RS04415	COG0463	Glycosyl transferase, family 2
C7M53_RS04425	COG4485	Bacterial membrane protein, YfhO
C7M53_RS04430	COG1988	membrane-bound metal-dependent
C7M53_RS04435	COG1194	a g-specific adenine glycosylase
C7M53_RS04445	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS04460	COG3557	Belongs to the UPF0374 family
C7M53_RS04465	COG1132	(ABC) transporter
C7M53_RS04470	COG0444	Belongs to the ABC transporter superfamily
C7M53_RS04475	COG4608	Belongs to the ABC transporter superfamily
C7M53_RS04480	COG0747	negative chemotaxis
C7M53_RS04485	COG0601	transmembrane transport
C7M53_RS04490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS04495	COG4129	membrane
C7M53_RS04500	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M53_RS04505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7M53_RS04510	COG0735	belongs to the Fur family
C7M53_RS04620	COG0457	Tetratricopeptide repeat
C7M53_RS04665	COG5444	nuclease activity
C7M53_RS04670	COG0457	Tetratricopeptide repeat
C7M53_RS04675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M53_RS04685	COG0710	3-dehydroquinate dehydratase activity
C7M53_RS04690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7M53_RS04695	COG1116	anion transmembrane transporter activity
C7M53_RS04700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M53_RS04705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M53_RS04710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_RS04720	COG1476	TRANSCRIPTIONal
C7M53_RS04730	COG1131	(ABC) transporter
C7M53_RS04750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_RS04760	COG3382	B3 4 domain protein
C7M53_RS04765	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7M53_RS04775	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7M53_RS04780	COG0789	Transcriptional regulator
C7M53_RS04785	COG1664	Polymer-forming cytoskeletal
C7M53_RS04795	COG2766	serine protein kinase
C7M53_RS04800	COG2718	Belongs to the UPF0229 family
C7M53_RS04810	COG1566	PFAM secretion protein HlyD family protein
C7M53_RS04815	COG2814	Major facilitator Superfamily
C7M53_RS04820	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS04835	COG1131	(ABC) transporter
C7M53_RS04840	COG1131	(ABC) transporter
C7M53_RS04845	COG1131	(ABC) transporter
C7M53_RS04850	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_RS04855	COG1278	Cold shock
C7M53_RS04860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M53_RS04865	COG2011	ABC-type metal ion transport system permease component
C7M53_RS04870	COG1464	Belongs to the NlpA lipoprotein family
C7M53_RS04875	COG1823	symporter activity
C7M53_RS04900	COG5577	PFAM Coat F domain
C7M53_RS04905	COG5002	protein histidine kinase activity
C7M53_RS04910	COG1525	nuclease
C7M53_RS04910	COG0737	Belongs to the 5'-nucleotidase family
C7M53_RS04910	COG4085	toxin activity
C7M53_RS04915	COG3764	Sortase (surface protein transpeptidase)
C7M53_RS04920	COG0564	pseudouridine synthase activity
C7M53_RS04930	COG0517	IMP dehydrogenase activity
C7M53_RS04935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7M53_RS04940	COG3153	acetyltransferase
C7M53_RS04940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M53_RS04945	COG0488	(ABC) transporter
C7M53_RS04955	COG2116	formate transmembrane transporter activity
C7M53_RS04960	COG0679	Auxin Efflux Carrier
C7M53_RS04965	COG0604	alcohol dehydrogenase
C7M53_RS04970	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
C7M53_RS04975	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7M53_RS04980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7M53_RS04985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7M53_RS04990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7M53_RS05005	COG2203	Gaf domain
C7M53_RS05005	COG4585	Histidine kinase
C7M53_RS05010	COG2197	response regulator
C7M53_RS05015	COG0431	NADPH-dependent FMN reductase
C7M53_RS05030	COG1959	2 iron, 2 sulfur cluster binding
C7M53_RS05035	COG1017	nitric oxide dioxygenase activity
C7M53_RS05035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7M53_RS05040	COG2719	SpoVR family
C7M53_RS05045	COG1388	LysM domain
C7M53_RS05045	COG0791	NLP P60 protein
C7M53_RS05050	COG0583	DNA-binding transcription factor activity
C7M53_RS05055	COG0372	Belongs to the citrate synthase family
C7M53_RS05060	COG2133	pyrroloquinoline quinone binding
C7M53_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS05070	COG0733	neurotransmitter:sodium symporter activity
C7M53_RS05080	COG3708	Transcriptional regulator
C7M53_RS05080	COG2207	Transcriptional regulator
C7M53_RS05105	COG1595	DNA-templated transcription, initiation
C7M53_RS05110	COG0662	Cupin 2, conserved barrel domain protein
C7M53_RS05120	COG0204	Acyl-transferase
C7M53_RS05125	COG3152	Membrane
C7M53_RS05135	COG1309	transcriptional regulator
C7M53_RS05140	COG1253	flavin adenine dinucleotide binding
C7M53_RS05145	COG0789	Transcriptional regulator
C7M53_RS05150	COG1253	flavin adenine dinucleotide binding
C7M53_RS05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M53_RS05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7M53_RS05180	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_RS05190	COG0668	transmembrane transport
C7M53_RS05195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7M53_RS05210	COG0726	polysaccharide deacetylase
C7M53_RS05220	COG1757	Na H antiporter
C7M53_RS05225	COG2017	converts alpha-aldose to the beta-anomer
C7M53_RS05250	COG0589	response to stress
C7M53_RS05255	COG1132	(ABC) transporter
C7M53_RS05260	COG1132	(ABC) transporter
C7M53_RS05265	COG0702	epimerase
C7M53_RS05280	COG3842	ATPase activity
C7M53_RS05285	COG2508	Transcriptional regulator
C7M53_RS05295	COG0189	ligase activity
C7M53_RS05300	COG0189	ligase activity
C7M53_RS05305	COG4399	Belongs to the UPF0754 family
C7M53_RS05310	COG3679	Belongs to the UPF0342 family
C7M53_RS05325	COG0561	phosphatase activity
C7M53_RS05330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M53_RS05335	COG0475	glutathione-regulated potassium exporter activity
C7M53_RS05340	COG0490	domain, Protein
C7M53_RS05350	COG1024	Enoyl-CoA hydratase
C7M53_RS05355	COG0457	Tetratricopeptide repeat
C7M53_RS05370	COG4152	abc transporter atp-binding protein
C7M53_RS05375	COG1668	transmembrane transport
C7M53_RS05380	COG0420	3'-5' exonuclease activity
C7M53_RS05385	COG4717	serine-type aminopeptidase activity
C7M53_RS05390	COG3481	metal-dependent phosphohydrolase, HD sub domain
C7M53_RS05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7M53_RS05430	COG1846	Transcriptional regulator
C7M53_RS05435	COG4980	gas vesicle protein
C7M53_RS05450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7M53_RS05455	COG0537	adenosine 5'-monophosphoramidase activity
C7M53_RS05465	COG1131	(ABC) transporter
C7M53_RS05470	COG4473	ABC transporter
C7M53_RS05480	COG1473	amidohydrolase
C7M53_RS05490	COG2329	Antibiotic biosynthesis monooxygenase
C7M53_RS05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_RS05500	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7M53_RS05505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7M53_RS05510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
C7M53_RS05515	COG1309	transcriptional regulator
C7M53_RS05520	COG1511	domain protein
C7M53_RS05530	COG1363	Peptidase, m42
C7M53_RS05540	COG1301	dicarboxylic acid transport
C7M53_RS05550	COG1234	tRNA 3'-trailer cleavage
C7M53_RS05555	COG0095	Lipoate-protein ligase
C7M53_RS05560	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS05570	COG1396	sequence-specific DNA binding
C7M53_RS05585	COG0501	Belongs to the peptidase M48B family
C7M53_RS05595	COG0697	spore germination
C7M53_RS05600	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7M53_RS05605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS05610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS05615	COG0406	alpha-ribazole phosphatase activity
C7M53_RS05620	COG0840	transmembrane signaling receptor activity
C7M53_RS05625	COG0723	plastoquinol--plastocyanin reductase activity
C7M53_RS05625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M53_RS05630	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS05640	COG4903	ComK protein
C7M53_RS05650	COG0398	Pfam SNARE associated Golgi protein
C7M53_RS05655	COG0681	Belongs to the peptidase S26 family
C7M53_RS05665	COG1404	Belongs to the peptidase S8 family
C7M53_RS05675	COG2508	Transcriptional regulator
C7M53_RS05685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M53_RS05690	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_RS05695	COG3257	ureidoglycine aminohydrolase activity
C7M53_RS05700	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M53_RS05705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C7M53_RS05710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_RS05715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_RS05725	COG0549	Belongs to the carbamate kinase family
C7M53_RS05730	COG2814	Major facilitator Superfamily
C7M53_RS05740	COG0457	Tetratricopeptide repeat
C7M53_RS05760	COG1609	Transcriptional regulator
C7M53_RS05765	COG1653	transport
C7M53_RS05770	COG1175	transmembrane transport
C7M53_RS05775	COG0395	ABC-type sugar transport system, permease component
C7M53_RS05780	COG1486	melibiose metabolic process
C7M53_RS05785	COG3180	Ammonia monooxygenase
C7M53_RS05800	COG3546	catalase activity
C7M53_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS05810	COG0477	Major facilitator Superfamily
C7M53_RS05810	COG2814	Major facilitator Superfamily
C7M53_RS05820	COG5002	protein histidine kinase activity
C7M53_RS05825	COG0745	RESPONSE REGULATOR receiver
C7M53_RS05830	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M53_RS05835	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7M53_RS05840	COG4149	molybdate abc transporter
C7M53_RS05845	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
C7M53_RS05850	COG1074	ATP-dependent DNA helicase activity
C7M53_RS05855	COG0420	3'-5' exonuclease activity
C7M53_RS05860	COG0419	ATPase involved in DNA repair
C7M53_RS05905	COG5337	Spore coat protein CotH
C7M53_RS05915	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7M53_RS05940	COG0367	asparagine synthase
C7M53_RS05945	COG0004	ammonium transporteR
C7M53_RS05950	COG0347	Belongs to the P(II) protein family
C7M53_RS05955	COG0534	Mate efflux family protein
C7M53_RS05960	COG2207	Transcriptional regulator
C7M53_RS05960	COG1917	Cupin 2, conserved barrel domain protein
C7M53_RS05970	COG1609	Transcriptional regulator
C7M53_RS05975	COG0673	inositol 2-dehydrogenase activity
C7M53_RS05980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_RS05990	COG0076	glutamate decarboxylase activity
C7M53_RS06015	COG2153	protein acetylation
C7M53_RS06020	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS06025	COG2378	regulation of single-species biofilm formation
C7M53_RS06030	COG0646	methionine synthase
C7M53_RS06030	COG1410	methionine synthase
C7M53_RS06035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7M53_RS06035	COG0646	methionine synthase
C7M53_RS06040	COG1666	GTP binding
C7M53_RS06045	COG2996	Protein conserved in bacteria
C7M53_RS06060	COG1307	EDD domain protein, DegV family
C7M53_RS06065	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS06075	COG0516	GMP reductase activity
C7M53_RS06085	COG0561	phosphatase activity
C7M53_RS06090	COG1073	alpha beta
C7M53_RS06095	COG2151	metal-sulfur cluster biosynthetic enzyme
C7M53_RS06105	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7M53_RS06110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7M53_RS06115	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7M53_RS06120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7M53_RS06125	COG0505	Belongs to the CarA family
C7M53_RS06130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M53_RS06135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M53_RS06140	COG1968	undecaprenyl-diphosphatase activity
C7M53_RS06155	COG2267	carboxylic ester hydrolase activity
C7M53_RS06165	COG1744	ABC transporter substrate-binding protein PnrA-like
C7M53_RS06180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M53_RS06185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7M53_RS06190	COG5504	Zn-dependent protease
C7M53_RS06195	COG0444	Belongs to the ABC transporter superfamily
C7M53_RS06200	COG4608	Belongs to the ABC transporter superfamily
C7M53_RS06210	COG0601	transmembrane transport
C7M53_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS06230	COG0180	Tryptophanyl-tRNA synthetase
C7M53_RS06240	COG4166	transmembrane transport
C7M53_RS06245	COG0601	transmembrane transport
C7M53_RS06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS06260	COG4608	Belongs to the ABC transporter superfamily
C7M53_RS06265	COG0456	acetyltransferase
C7M53_RS06270	COG1393	Belongs to the ArsC family
C7M53_RS06275	COG0861	Integral membrane protein TerC family
C7M53_RS06285	COG4862	establishment of competence for transformation
C7M53_RS06305	COG4565	transcriptional regulatory protein
C7M53_RS06310	COG3290	protein histidine kinase activity
C7M53_RS06315	COG4469	Competence protein
C7M53_RS06320	COG1164	Oligoendopeptidase f
C7M53_RS06325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7M53_RS06330	COG2346	COG2346, Truncated hemoglobins
C7M53_RS06335	COG0741	lytic transglycosylase activity
C7M53_RS06340	COG4116	CYTH
C7M53_RS06350	COG2357	RelA SpoT domain protein
C7M53_RS06355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M53_RS06360	COG0564	pseudouridine synthase activity
C7M53_RS06365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7M53_RS06375	COG0569	domain protein
C7M53_RS06375	COG0475	glutathione-regulated potassium exporter activity
C7M53_RS06380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7M53_RS06385	COG0352	thiamine-phosphate diphosphorylase activity
C7M53_RS06395	COG2104	thiamine diphosphate biosynthetic process
C7M53_RS06400	COG2022	thiamine diphosphate biosynthetic process
C7M53_RS06405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M53_RS06410	COG0351	phosphomethylpyrimidine kinase
C7M53_RS06415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7M53_RS06470	COG0210	DNA helicase
C7M53_RS06480	COG0586	Pfam SNARE associated Golgi protein
C7M53_RS06485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_RS06490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M53_RS06495	COG2246	polysaccharide biosynthetic process
C7M53_RS06500	COG2153	protein acetylation
C7M53_RS06505	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M53_RS06510	COG2382	esterase
C7M53_RS06530	COG0626	cystathionine gamma-synthase activity
C7M53_RS06535	COG0626	cystathionine gamma-synthase activity
C7M53_RS06540	COG5505	Protein of unknown function (DUF819)
C7M53_RS06555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_RS06560	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M53_RS06580	COG0110	maltose O-acetyltransferase activity
C7M53_RS06590	COG0583	DNA-binding transcription factor activity
C7M53_RS06600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M53_RS06605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7M53_RS06610	COG0583	DNA-binding transcription factor activity
C7M53_RS06615	COG0697	spore germination
C7M53_RS06620	COG0346	lactoylglutathione lyase activity
C7M53_RS06630	COG3584	3D domain protein
C7M53_RS06630	COG1388	LysM domain
C7M53_RS06635	COG2814	Major facilitator Superfamily
C7M53_RS06640	COG1309	transcriptional regulator
C7M53_RS06660	COG5444	nuclease activity
C7M53_RS06665	COG4195	phage-related replication protein
C7M53_RS06670	COG2856	Zn peptidase
C7M53_RS06675	COG1396	sequence-specific DNA binding
C7M53_RS06690	COG1522	sequence-specific DNA binding
C7M53_RS06695	COG1484	DNA-dependent DNA replication
C7M53_RS06710	COG1595	DNA-templated transcription, initiation
C7M53_RS06715	COG5484	DNA packaging
C7M53_RS06715	COG3728	DNA packaging
C7M53_RS06720	COG1783	phage Terminase large subunit
C7M53_RS06725	COG5518	Phage portal protein
C7M53_RS06730	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7M53_RS06735	COG4653	Phage capsid family
C7M53_RS06785	COG3953	SLT domain
C7M53_RS06785	COG5412	phage tail tape measure protein
C7M53_RS06790	COG1652	LysM domain
C7M53_RS06795	COG4193	domain, Protein
C7M53_RS06805	COG3628	GPW Gp25 family protein
C7M53_RS06810	COG3299	homolog of phage Mu protein gp47
C7M53_RS06815	COG3778	Protein conserved in bacteria
C7M53_RS06855	COG1802	Transcriptional regulator
C7M53_RS06860	COG1063	alcohol dehydrogenase
C7M53_RS06865	COG1312	Catalyzes the dehydration of D-mannonate
C7M53_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS06875	COG1063	alcohol dehydrogenase
C7M53_RS06880	COG2271	Major facilitator Superfamily
C7M53_RS06895	COG0306	phosphate transporter
C7M53_RS06900	COG1392	Phosphate transport regulator
C7M53_RS06905	COG0405	Gamma-glutamyltransferase
C7M53_RS06910	COG5578	integral membrane protein
C7M53_RS06925	COG2207	Transcriptional regulator
C7M53_RS06930	COG2755	lipolytic protein G-D-S-L family
C7M53_RS06940	COG5578	integral membrane protein
C7M53_RS06945	COG3401	FG-GAP repeat protein
C7M53_RS06955	COG2755	lipolytic protein G-D-S-L family
C7M53_RS06960	COG3401	FG-GAP repeat protein
C7M53_RS06965	COG0667	Aldo Keto reductase
C7M53_RS06970	COG2755	lipolytic protein G-D-S-L family
C7M53_RS06975	COG1874	Beta-galactosidase
C7M53_RS06985	COG1653	transport
C7M53_RS06990	COG4209	transmembrane transport
C7M53_RS06995	COG0395	ABC-type sugar transport system, permease component
C7M53_RS07000	COG0531	amino acid
C7M53_RS07005	COG0346	lactoylglutathione lyase activity
C7M53_RS07015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_RS07020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_RS07025	COG2362	D-Aminopeptidase
C7M53_RS07030	COG0601	transmembrane transport
C7M53_RS07035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS07040	COG0444	Belongs to the ABC transporter superfamily
C7M53_RS07045	COG4166	transmembrane transport
C7M53_RS07050	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7M53_RS07055	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_RS07060	COG0791	NLP P60 protein
C7M53_RS07065	COG4608	Belongs to the ABC transporter superfamily
C7M53_RS07070	COG1834	amidinotransferase
C7M53_RS07075	COG1607	acyl-coa hydrolase
C7M53_RS07085	COG3866	Pectate lyase
C7M53_RS07105	COG2318	DinB family
C7M53_RS07110	COG2076	Multidrug Resistance protein
C7M53_RS07115	COG2076	Multidrug Resistance protein
C7M53_RS07120	COG0788	formyltetrahydrofolate deformylase activity
C7M53_RS07125	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M53_RS07130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M53_RS07135	COG1764	response to oxidative stress
C7M53_RS07140	COG1846	Transcriptional regulator
C7M53_RS07145	COG1764	response to oxidative stress
C7M53_RS07155	COG0590	tRNA wobble adenosine to inosine editing
C7M53_RS07160	COG0406	alpha-ribazole phosphatase activity
C7M53_RS07175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M53_RS07180	COG1404	Belongs to the peptidase S8 family
C7M53_RS07190	COG2239	Acts as a magnesium transporter
C7M53_RS07200	COG0582	viral genome integration into host DNA
C7M53_RS07205	COG2856	Zn peptidase
C7M53_RS07225	COG3620	sequence-specific DNA binding
C7M53_RS07265	COG5377	YqaJ viral recombinase family
C7M53_RS07270	COG3723	Recombinational DNA repair protein, rece pathway
C7M53_RS07275	COG3935	DnaD domain protein
C7M53_RS07280	COG1484	DNA-dependent DNA replication
C7M53_RS07310	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
C7M53_RS07325	COG0629	single-stranded DNA binding
C7M53_RS07370	COG5484	DNA packaging
C7M53_RS07375	COG1783	phage Terminase large subunit
C7M53_RS07500	COG5444	nuclease activity
C7M53_RS07520	COG0789	Transcriptional regulator
C7M53_RS07535	COG1846	Transcriptional regulator
C7M53_RS07540	COG1793	dna ligase
C7M53_RS07540	COG3285	dna ligase
C7M53_RS07545	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
C7M53_RS07550	COG5001	Diguanylate cyclase
C7M53_RS07550	COG3300	MHYT domain
C7M53_RS07555	COG0586	Pfam SNARE associated Golgi protein
C7M53_RS07560	COG0861	Integral membrane protein TerC family
C7M53_RS07565	COG1191	sigma factor activity
C7M53_RS07585	COG0501	Belongs to the peptidase M48B family
C7M53_RS07590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_RS07595	COG0768	penicillin binding
C7M53_RS07610	COG3594	Acyltransferase
C7M53_RS07615	COG5002	protein histidine kinase activity
C7M53_RS07620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M53_RS07625	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
C7M53_RS07630	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
C7M53_RS07635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7M53_RS07640	COG0436	Aminotransferase
C7M53_RS07645	COG1850	ribulose-bisphosphate carboxylase activity
C7M53_RS07650	COG0235	Class ii aldolase
C7M53_RS07650	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
C7M53_RS07655	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7M53_RS07660	COG0346	lactoylglutathione lyase activity
C7M53_RS07665	COG3339	Conserved Protein
C7M53_RS07675	COG3852	Histidine kinase
C7M53_RS07680	COG1846	Transcriptional regulator
C7M53_RS07685	COG1360	Flagellar Motor Protein
C7M53_RS07690	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M53_RS07695	COG0542	response to heat
C7M53_RS07700	COG3949	Membrane
C7M53_RS07705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7M53_RS07710	COG0720	synthase
C7M53_RS07715	COG0602	queuosine metabolic process
C7M53_RS07720	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7M53_RS07730	COG4974	Belongs to the 'phage' integrase family
C7M53_RS07735	COG4974	Belongs to the 'phage' integrase family
C7M53_RS07790	COG5444	nuclease activity
C7M53_RS07880	COG0582	viral genome integration into host DNA
C7M53_RS08010	COG1388	LysM domain
C7M53_RS08010	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS08010	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_RS08035	COG0582	viral genome integration into host DNA
C7M53_RS08050	COG3739	integral membrane protein
C7M53_RS08055	COG3655	Transcriptional regulator
C7M53_RS08085	COG4873	Protein conserved in bacteria
C7M53_RS08095	COG3773	Cell wall hydrolase
C7M53_RS08100	COG2244	polysaccharide biosynthetic process
C7M53_RS08105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS08110	COG2217	Heavy metal translocating P-type atpase
C7M53_RS08115	COG0006	proline dipeptidase activity
C7M53_RS08125	COG1609	Transcriptional regulator
C7M53_RS08130	COG3711	transcriptional antiterminator
C7M53_RS08135	COG1263	PTS System
C7M53_RS08135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS08135	COG2190	(PTS) system
C7M53_RS08140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS08145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7M53_RS08155	COG1533	DNA photolyase activity
C7M53_RS08160	COG0456	acetyltransferase
C7M53_RS08165	COG0840	transmembrane signaling receptor activity
C7M53_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS08175	COG2084	Dehydrogenase
C7M53_RS08180	COG2340	Cysteine-rich secretory protein family
C7M53_RS08185	COG0768	penicillin binding
C7M53_RS08190	COG4191	Histidine kinase
C7M53_RS08195	COG0436	Aminotransferase
C7M53_RS08200	COG1714	RDD family
C7M53_RS08210	COG0784	Response regulator, receiver
C7M53_RS08210	COG0835	chemotaxis
C7M53_RS08220	COG2814	Major facilitator Superfamily
C7M53_RS08225	COG1376	ErfK ybiS ycfS ynhG family protein
C7M53_RS08235	COG1408	metallophosphoesterase
C7M53_RS08240	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS08245	COG2200	EAL domain
C7M53_RS08255	COG4703	Protein of unknown function (DUF1797)
C7M53_RS08260	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
C7M53_RS08270	COG0517	IMP dehydrogenase activity
C7M53_RS08275	COG0583	DNA-binding transcription factor activity
C7M53_RS08280	COG0716	FMN binding
C7M53_RS08290	COG0716	FMN binding
C7M53_RS08295	COG2171	N-acyltransferase activity
C7M53_RS08300	COG1473	amidohydrolase
C7M53_RS08310	COG0450	alkyl hydroperoxide reductase
C7M53_RS08315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS08330	COG0746	molybdenum cofactor guanylyltransferase activity
C7M53_RS08335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7M53_RS08340	COG0303	'Molybdopterin
C7M53_RS08345	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7M53_RS08350	COG0314	molybdopterin synthase activity
C7M53_RS08355	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7M53_RS08365	COG1132	(ABC) transporter
C7M53_RS08370	COG1132	(ABC) transporter
C7M53_RS08380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7M53_RS08385	COG1136	(ABC) transporter
C7M53_RS08390	COG0577	efflux transmembrane transporter activity
C7M53_RS08395	COG1349	DNA-binding transcription factor activity
C7M53_RS08400	COG1105	Belongs to the carbohydrate kinase PfkB family
C7M53_RS08405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS08405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS08405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS08425	COG0488	(ABC) transporter
C7M53_RS08435	COG2309	aminopeptidase activity
C7M53_RS08445	COG1077	Cell shape determining protein MreB Mrl
C7M53_RS08450	COG2002	toxin-antitoxin pair type II binding
C7M53_RS08455	COG3852	Histidine kinase
C7M53_RS08460	COG0569	domain protein
C7M53_RS08465	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7M53_RS08470	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M53_RS08475	COG5503	Protein of unknown function (DUF1447)
C7M53_RS08480	COG0561	phosphatase activity
C7M53_RS08485	COG0242	peptide deformylase activity
C7M53_RS08495	COG0497	DNA recombination
C7M53_RS08500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_RS08505	COG0022	dehydrogenase e1 component
C7M53_RS08510	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_RS08515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_RS08520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS08530	COG1982	Orn Lys Arg decarboxylase major
C7M53_RS08535	COG4476	Belongs to the UPF0223 family
C7M53_RS08540	COG4493	Belongs to the UPF0637 family
C7M53_RS08550	COG0483	inositol monophosphate 1-phosphatase activity
C7M53_RS08570	COG1595	DNA-templated transcription, initiation
C7M53_RS08585	COG1217	gtp-binding protein TYPA
C7M53_RS08595	COG1846	Transcriptional regulator
C7M53_RS08600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7M53_RS08605	COG4896	Protein conserved in bacteria
C7M53_RS08615	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7M53_RS08620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M53_RS08625	COG2066	Belongs to the glutaminase family
C7M53_RS08630	COG4838	Belongs to the UPF0358 family
C7M53_RS08635	COG0772	Belongs to the SEDS family
C7M53_RS08640	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
C7M53_RS08645	COG1612	heme a metabolic process
C7M53_RS08650	COG0109	protoheme IX farnesyltransferase activity
C7M53_RS08655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M53_RS08655	COG2010	Cytochrome c
C7M53_RS08660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M53_RS08665	COG1845	cytochrome c oxidase, subunit III
C7M53_RS08670	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M53_RS08675	COG3336	cytochrome c oxidase
C7M53_RS08685	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
C7M53_RS08690	COG2340	Cysteine-rich secretory protein family
C7M53_RS08705	COG3679	Belongs to the UPF0342 family
C7M53_RS08710	COG4471	UPF0298 protein
C7M53_RS08715	COG0742	ribosomal rna small subunit methyltransferase
C7M53_RS08720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7M53_RS08725	COG3314	Sporulation integral membrane protein YlbJ
C7M53_RS08730	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7M53_RS08735	COG1323	Belongs to the UPF0348 family
C7M53_RS08740	COG1399	metal-binding, possibly nucleic acid-binding protein
C7M53_RS08745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7M53_RS08755	COG0454	-acetyltransferase
C7M53_RS08760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7M53_RS08765	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
C7M53_RS08770	COG2001	Belongs to the MraZ family
C7M53_RS08775	COG0275	rRNA processing
C7M53_RS08780	COG4839	cell division protein FtsL
C7M53_RS08785	COG0768	penicillin binding
C7M53_RS08790	COG0768	penicillin binding
C7M53_RS08795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7M53_RS08800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M53_RS08805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M53_RS08810	COG0772	Belongs to the SEDS family
C7M53_RS08815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_RS08820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7M53_RS08825	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7M53_RS08830	COG3879	Bacterial protein of unknown function (DUF881)
C7M53_RS08835	COG3879	Bacterial protein of unknown function (DUF881)
C7M53_RS08840	COG3856	small basic protein
C7M53_RS08845	COG0849	cell division
C7M53_RS08850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7M53_RS08855	COG1404	Belongs to the peptidase S8 family
C7M53_RS08855	COG4412	M6 family metalloprotease domain protein
C7M53_RS08870	COG1191	sigma factor activity
C7M53_RS08875	COG1191	sigma factor activity
C7M53_RS08880	COG1119	ATPase activity
C7M53_RS08885	COG0500	methyltransferase
C7M53_RS08890	COG1873	PFAM PRC-barrel domain
C7M53_RS08895	COG1496	oxidoreductase activity
C7M53_RS08900	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7M53_RS08905	COG1799	cell septum assembly
C7M53_RS08910	COG0762	integral membrane protein
C7M53_RS08915	COG2302	S4 RNA-binding domain
C7M53_RS08920	COG3599	regulation of cell shape
C7M53_RS08925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7M53_RS08930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_RS08935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7M53_RS08940	COG0564	pseudouridine synthase activity
C7M53_RS08945	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
C7M53_RS08950	COG2233	PERMEase
C7M53_RS08955	COG0540	Belongs to the ATCase OTCase family
C7M53_RS08960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7M53_RS08965	COG0505	Belongs to the CarA family
C7M53_RS08970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7M53_RS08975	COG0543	2 iron, 2 sulfur cluster binding
C7M53_RS08980	COG0167	dihydroorotate dehydrogenase activity
C7M53_RS08985	COG0284	orotidine-5'-phosphate decarboxylase activity
C7M53_RS08990	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7M53_RS09000	COG0175	sulfate reduction
C7M53_RS09005	COG0306	phosphate transporter
C7M53_RS09010	COG2046	Belongs to the sulfate adenylyltransferase family
C7M53_RS09015	COG0529	Catalyzes the synthesis of activated sulfate
C7M53_RS09020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7M53_RS09025	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
C7M53_RS09030	COG1648	precorrin-2 dehydrogenase activity
C7M53_RS09040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7M53_RS09045	COG1561	YicC-like family, N-terminal region
C7M53_RS09050	COG2052	Domain of unknown function (DUF370)
C7M53_RS09055	COG0194	GDP metabolic process
C7M53_RS09060	COG1758	RNA polymerase activity
C7M53_RS09065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M53_RS09070	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7M53_RS09075	COG0242	peptide deformylase activity
C7M53_RS09080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7M53_RS09085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7M53_RS09085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M53_RS09090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7M53_RS09095	COG0631	protein serine/threonine phosphatase activity
C7M53_RS09100	COG2815	serine threonine protein kinase
C7M53_RS09100	COG0515	serine threonine protein kinase
C7M53_RS09105	COG1162	GTPase activity
C7M53_RS09110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7M53_RS09115	COG1564	THIamine pyrophosphokinase
C7M53_RS09125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7M53_RS09130	COG1302	Protein conserved in bacteria
C7M53_RS09135	COG1461	Dihydroxyacetone kinase
C7M53_RS09140	COG1760	l-serine dehydratase
C7M53_RS09145	COG1760	l-serine dehydratase
C7M53_RS09150	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7M53_RS09155	COG1349	DNA-binding transcription factor activity
C7M53_RS09160	COG0416	fatty acid biosynthetic process
C7M53_RS09165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7M53_RS09170	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS09175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M53_RS09180	COG0571	ribonuclease III activity
C7M53_RS09185	COG1196	nuclear chromosome segregation
C7M53_RS09190	COG0552	protein localization to endoplasmic reticulum
C7M53_RS09195	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
C7M53_RS09200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7M53_RS09205	COG0228	four-way junction DNA binding
C7M53_RS09210	COG1837	Belongs to the UPF0109 family
C7M53_RS09220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7M53_RS09225	COG0336	Belongs to the RNA methyltransferase TrmD family
C7M53_RS09230	COG0335	large ribosomal subunit rRNA binding
C7M53_RS09235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M53_RS09240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M53_RS09250	COG2257	FlhB HrpN YscU SpaS Family
C7M53_RS09255	COG0045	succinate-CoA ligase (ADP-forming) activity
C7M53_RS09260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7M53_RS09265	COG0758	DNA mediated transformation
C7M53_RS09270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7M53_RS09275	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
C7M53_RS09280	COG4974	Belongs to the 'phage' integrase family
C7M53_RS09285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7M53_RS09290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7M53_RS09295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M53_RS09300	COG1815	bacterial-type flagellum-dependent cell motility
C7M53_RS09305	COG1558	bacterial-type flagellum-dependent cell motility
C7M53_RS09310	COG1677	Flagellar hook-basal body complex protein FliE
C7M53_RS09315	COG1766	The M ring may be actively involved in energy transduction
C7M53_RS09320	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_RS09325	COG1317	bacterial-type flagellum organization
C7M53_RS09330	COG1157	protein secretion by the type III secretion system
C7M53_RS09335	COG2882	bacterial-type flagellum organization
C7M53_RS09345	COG3144	bacterial-type flagellum assembly
C7M53_RS09350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7M53_RS09355	COG4786	Flagellar basal body rod
C7M53_RS09360	COG1582	Flagellar protein (FlbD)
C7M53_RS09365	COG1580	Controls the rotational direction of flagella during chemotaxis
C7M53_RS09370	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_RS09375	COG1776	CheC inhibitor of MCP methylation
C7M53_RS09375	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7M53_RS09380	COG2201	protein-glutamate methylesterase activity
C7M53_RS09385	COG3190	flagellar
C7M53_RS09390	COG1338	Plays a role in the flagellum-specific transport system
C7M53_RS09395	COG1987	bacterial-type flagellum assembly
C7M53_RS09400	COG1684	flagellar biosynthetic protein fliR
C7M53_RS09405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M53_RS09410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7M53_RS09415	COG1419	protein localization to endoplasmic reticulum
C7M53_RS09420	COG0455	bacterial-type flagellum organization
C7M53_RS09425	COG2201	protein-glutamate methylesterase activity
C7M53_RS09430	COG2198	Histidine kinase
C7M53_RS09430	COG0643	Histidine kinase
C7M53_RS09435	COG0835	chemotaxis
C7M53_RS09440	COG1776	CheC inhibitor of MCP methylation
C7M53_RS09445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C7M53_RS09450	COG1191	sigma factor activity
C7M53_RS09460	COG0052	Belongs to the universal ribosomal protein uS2 family
C7M53_RS09465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7M53_RS09470	COG0528	UMP kinase activity
C7M53_RS09475	COG0233	cytoplasmic translational termination
C7M53_RS09480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7M53_RS09485	COG4589	Belongs to the CDS family
C7M53_RS09490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7M53_RS09495	COG0750	zinc metalloprotease
C7M53_RS09500	COG0442	prolyl-tRNA aminoacylation
C7M53_RS09505	COG2176	DNA-directed DNA polymerase activity
C7M53_RS09535	COG0779	Required for maturation of 30S ribosomal subunits
C7M53_RS09540	COG0195	Participates in both transcription termination and antitermination
C7M53_RS09545	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7M53_RS09550	COG1358	cellular component organization or biogenesis
C7M53_RS09555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7M53_RS09560	COG1550	Protein conserved in bacteria
C7M53_RS09565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7M53_RS09570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7M53_RS09575	COG0196	riboflavin kinase activity
C7M53_RS09580	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7M53_RS09585	COG1185	polyribonucleotide nucleotidyltransferase activity
C7M53_RS09590	COG0726	polysaccharide deacetylase
C7M53_RS09595	COG0612	Peptidase, M16
C7M53_RS09600	COG1873	PFAM PRC-barrel domain
C7M53_RS09605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_RS09610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7M53_RS09615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7M53_RS09620	COG0527	aspartate kinase activity
C7M53_RS09630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
C7M53_RS09635	COG0740	serine-type endopeptidase activity
C7M53_RS09645	COG1674	ftsk spoiiie
C7M53_RS09645	COG4980	gas vesicle protein
C7M53_RS09650	COG2188	Transcriptional regulator
C7M53_RS09655	COG2814	Major facilitator Superfamily
C7M53_RS09660	COG0612	Peptidase, M16
C7M53_RS09665	COG0612	Peptidase, M16
C7M53_RS09670	COG0300	oxidoreductase activity
C7M53_RS09685	COG1426	Protein conserved in bacteria
C7M53_RS09690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7M53_RS09695	COG1546	Belongs to the CinA family
C7M53_RS09695	COG1058	Belongs to the CinA family
C7M53_RS09705	COG1418	mRNA catabolic process
C7M53_RS09710	COG1692	metallophosphoesterase
C7M53_RS09715	COG2359	stage V sporulation protein S
C7M53_RS09725	COG1063	alcohol dehydrogenase
C7M53_RS09730	COG0156	8-amino-7-oxononanoate synthase activity
C7M53_RS09735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M53_RS09740	COG4550	Control of competence regulator ComK, YlbF/YmcA
C7M53_RS09750	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7M53_RS09755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7M53_RS09760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7M53_RS09765	COG5444	nuclease activity
C7M53_RS09785	COG0523	cobalamin synthesis protein
C7M53_RS09795	COG1247	-acetyltransferase
C7M53_RS09815	COG3619	membrane
C7M53_RS09820	COG3263	regulation of cellular component size
C7M53_RS09840	COG0393	Putative heavy-metal-binding
C7M53_RS09845	COG0398	Pfam SNARE associated Golgi protein
C7M53_RS09850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7M53_RS09855	COG1819	glycosyl
C7M53_RS09860	COG0531	amino acid
C7M53_RS09865	COG5577	PFAM Coat F domain
C7M53_RS09875	COG3858	chitin binding
C7M53_RS09875	COG1388	LysM domain
C7M53_RS09880	COG1309	transcriptional regulator
C7M53_RS09885	COG3631	Ketosteroid isomerase-related protein
C7M53_RS09890	COG0702	epimerase
C7M53_RS09900	COG1764	response to oxidative stress
C7M53_RS09905	COG2076	Multidrug Resistance protein
C7M53_RS09910	COG2076	Multidrug Resistance protein
C7M53_RS09925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7M53_RS09930	COG1923	regulation of RNA biosynthetic process
C7M53_RS09945	COG1780	Probably involved in ribonucleotide reductase function
C7M53_RS09950	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_RS09955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_RS09960	COG4112	unkown
C7M53_RS09975	COG0735	belongs to the Fur family
C7M53_RS09980	COG1802	Transcriptional regulator
C7M53_RS09985	COG0697	spore germination
C7M53_RS10020	COG1309	transcriptional regulator
C7M53_RS10070	COG0464	growth
C7M53_RS10075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7M53_RS10080	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
C7M53_RS10085	COG0789	Transcriptional regulator
C7M53_RS10090	COG0174	glutamine synthetase
C7M53_RS10130	COG1073	alpha beta
C7M53_RS10170	COG1309	transcriptional regulator
C7M53_RS10175	COG2076	Multidrug Resistance protein
C7M53_RS10180	COG2076	Multidrug Resistance protein
C7M53_RS10185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS10205	COG3546	catalase activity
C7M53_RS10230	COG1846	Transcriptional regulator
C7M53_RS10235	COG0778	Nitroreductase
C7M53_RS10240	COG0346	lactoylglutathione lyase activity
C7M53_RS10245	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M53_RS10250	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS10270	COG3209	COG3209 Rhs family protein
C7M53_RS10275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7M53_RS10280	COG1388	LysM domain
C7M53_RS10285	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M53_RS10290	COG4224	UPF0291 protein
C7M53_RS10295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7M53_RS10305	COG3763	UPF0154 protein
C7M53_RS10315	COG0785	Cytochrome C biogenesis protein
C7M53_RS10320	COG2201	protein-glutamate methylesterase activity
C7M53_RS10325	COG4846	Membrane protein involved in cytochrome C biogenesis
C7M53_RS10335	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M53_RS10350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7M53_RS10355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS10375	COG0824	Thioesterase
C7M53_RS10400	COG4841	protein insertion into membrane
C7M53_RS10405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7M53_RS10410	COG1832	CoA-binding protein
C7M53_RS10415	COG0187	DNA topoisomerase II activity
C7M53_RS10420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
C7M53_RS10425	COG1609	Transcriptional regulator
C7M53_RS10440	COG2160	L-arabinose isomerase activity
C7M53_RS10460	COG1115	amino acid carrier protein
C7M53_RS10470	COG2181	nitrate reductase activity
C7M53_RS10475	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
C7M53_RS10480	COG1140	nitrate reductase beta subunit
C7M53_RS10485	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
C7M53_RS10500	COG0535	radical SAM domain protein
C7M53_RS10505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M53_RS10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7M53_RS10520	COG2223	nitrite transmembrane transporter activity
C7M53_RS10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
C7M53_RS10550	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
C7M53_RS10560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS10570	COG0492	ferredoxin-NADP+ reductase activity
C7M53_RS10585	COG3420	alginic acid biosynthetic process
C7M53_RS10590	COG1114	Component of the transport system for branched-chain amino acids
C7M53_RS10595	COG1064	alcohol dehydrogenase
C7M53_RS10600	COG0789	Transcriptional regulator
C7M53_RS10630	COG1024	Enoyl-CoA hydratase
C7M53_RS10635	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS10640	COG2084	Dehydrogenase
C7M53_RS10645	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS10650	COG1482	cell wall glycoprotein biosynthetic process
C7M53_RS10655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS10655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS10655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS10680	COG3711	transcriptional antiterminator
C7M53_RS10680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS10695	COG1725	Transcriptional regulator
C7M53_RS10700	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS10705	COG1312	Catalyzes the dehydration of D-mannonate
C7M53_RS10720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C7M53_RS10730	COG1609	Transcriptional regulator
C7M53_RS10735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_RS10740	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C7M53_RS10745	COG0640	Transcriptional regulator
C7M53_RS10755	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
C7M53_RS10770	COG1649	PFAM Uncharacterised BCR, COG1649
C7M53_RS10775	COG2404	hydrolase activity, acting on ester bonds
C7M53_RS10780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7M53_RS10790	COG2027	D-alanyl-D-alanine carboxypeptidase
C7M53_RS10795	COG1252	NADH dehydrogenase
C7M53_RS10810	COG0166	Belongs to the GPI family
C7M53_RS10820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_RS10825	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M53_RS10830	COG1024	Enoyl-CoA hydratase
C7M53_RS10835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M53_RS10840	COG0511	ligase activity, forming carbon-carbon bonds
C7M53_RS10845	COG0439	Biotin carboxylase
C7M53_RS10850	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS10855	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS10860	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS10865	COG1733	regulation of RNA biosynthetic process
C7M53_RS10870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7M53_RS10875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7M53_RS10885	COG2323	membrane
C7M53_RS10895	COG0306	phosphate transporter
C7M53_RS10900	COG0175	sulfate reduction
C7M53_RS10905	COG1809	phosphosulfolactate synthase activity
C7M53_RS10910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS10920	COG2814	Major facilitator Superfamily
C7M53_RS10925	COG0463	Glycosyl transferase, family 2
C7M53_RS10940	COG0493	'glutamate synthase
C7M53_RS10945	COG0070	glutamate synthase
C7M53_RS10945	COG0069	glutamate synthase activity
C7M53_RS10945	COG0067	glutamate synthase
C7M53_RS10950	COG0583	DNA-binding transcription factor activity
C7M53_RS10970	COG1846	Transcriptional regulator
C7M53_RS10980	COG1132	(ABC) transporter
C7M53_RS10990	COG0300	oxidoreductase activity
C7M53_RS10995	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_RS10995	COG3848	Pyruvate phosphate dikinase
C7M53_RS11005	COG0477	Major facilitator Superfamily
C7M53_RS11010	COG0243	molybdopterin cofactor binding
C7M53_RS11015	COG1846	Transcriptional regulator
C7M53_RS11025	COG0531	amino acid
C7M53_RS11035	COG0531	amino acid
C7M53_RS11040	COG0531	amino acid
C7M53_RS11045	COG0697	spore germination
C7M53_RS11050	COG0488	(ABC) transporter
C7M53_RS11055	COG0840	transmembrane signaling receptor activity
C7M53_RS11060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_RS11065	COG1404	Belongs to the peptidase S8 family
C7M53_RS11075	COG1309	transcriptional regulator
C7M53_RS11080	COG1846	Transcriptional regulator
C7M53_RS11110	COG1309	transcriptional regulator
C7M53_RS11115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS11120	COG3708	Transcriptional regulator
C7M53_RS11130	COG2378	regulation of single-species biofilm formation
C7M53_RS11140	COG0640	Transcriptional regulator
C7M53_RS11145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS11155	COG0531	amino acid
C7M53_RS11160	COG0741	lytic transglycosylase activity
C7M53_RS11165	COG1086	Polysaccharide biosynthesis protein
C7M53_RS11185	COG2322	membrane
C7M53_RS11200	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS11205	COG3584	3D domain protein
C7M53_RS11205	COG1388	LysM domain
C7M53_RS11210	COG0514	ATP-dependent DNA helicase (RecQ)
C7M53_RS11230	COG2315	Protein conserved in bacteria
C7M53_RS11250	COG2427	Protein of unknown function (DUF1641)
C7M53_RS11255	COG3383	formate dehydrogenase (NAD+) activity
C7M53_RS11275	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C7M53_RS11325	COG0402	S-adenosylhomocysteine deaminase activity
C7M53_RS11340	COG2267	carboxylic ester hydrolase activity
C7M53_RS11355	COG1280	lysine exporter protein (LysE YggA)
C7M53_RS11360	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7M53_RS11370	COG0574	Belongs to the PEP-utilizing enzyme family
C7M53_RS11370	COG3848	Pyruvate phosphate dikinase
C7M53_RS11375	COG1309	transcriptional regulator
C7M53_RS11390	COG2318	DinB family
C7M53_RS11395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M53_RS11400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_RS11415	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS11420	COG2814	Major facilitator Superfamily
C7M53_RS11435	COG1657	PFAM Prenyltransferase squalene oxidase
C7M53_RS11440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M53_RS11450	COG0733	neurotransmitter:sodium symporter activity
C7M53_RS11455	COG0385	Bile acid
C7M53_RS11460	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_RS11465	COG0567	Dehydrogenase, E1 component
C7M53_RS11470	COG4548	von Willebrand factor, type A
C7M53_RS11475	COG0714	Associated with various cellular activities
C7M53_RS11480	COG2032	superoxide dismutase activity
C7M53_RS11485	COG1388	LysM domain
C7M53_RS11485	COG0791	NLP P60 protein
C7M53_RS11495	COG0534	Mate efflux family protein
C7M53_RS11500	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_RS11505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_RS11515	COG2962	Rard protein
C7M53_RS11525	COG4305	rare lipoprotein A
C7M53_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS11540	COG1733	regulation of RNA biosynthetic process
C7M53_RS11545	COG0778	Nitroreductase
C7M53_RS11550	COG0400	carboxylic ester hydrolase activity
C7M53_RS11560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS11565	COG0793	Belongs to the peptidase S41A family
C7M53_RS11565	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_RS11570	COG2226	methyltransferase
C7M53_RS11580	COG1876	peptidase activity
C7M53_RS11585	COG0813	purine-nucleoside phosphorylase activity
C7M53_RS11590	COG0701	Predicted permease
C7M53_RS11610	COG0671	phosphoesterase, PA-phosphatase related
C7M53_RS11625	COG4479	Belongs to the UPF0346 family
C7M53_RS11645	COG3331	DNA recombination
C7M53_RS11655	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C7M53_RS11720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7M53_RS11740	COG0756	dUTP diphosphatase activity
C7M53_RS11760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_RS11770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_RS11770	COG1372	Participates in initiation and elongation during chromosome replication
C7M53_RS11775	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7M53_RS11780	COG1780	Probably involved in ribonucleotide reductase function
C7M53_RS11840	COG3584	3D domain protein
C7M53_RS11845	COG0587	DNA-directed DNA polymerase activity
C7M53_RS11855	COG0587	DNA-directed DNA polymerase activity
C7M53_RS11860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M53_RS11865	COG0358	DNA primase activity
C7M53_RS11870	COG0305	Participates in initiation and elongation during chromosome replication
C7M53_RS11880	COG2887	Belongs to the helicase family. UvrD subfamily
C7M53_RS11935	COG1793	dna ligase
C7M53_RS11990	COG4474	Belongs to the UPF0398 family
C7M53_RS12000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M53_RS12035	COG0582	viral genome integration into host DNA
C7M53_RS12065	COG1404	Belongs to the peptidase S8 family
C7M53_RS12120	COG3655	Transcriptional regulator
C7M53_RS12185	COG1404	Belongs to the peptidase S8 family
C7M53_RS12215	COG0776	regulation of translation
C7M53_RS12250	COG4373	Mu-like prophage FluMu protein gp28
C7M53_RS12345	COG0582	viral genome integration into host DNA
C7M53_RS12370	COG3226	Transcriptional regulator
C7M53_RS12430	COG0741	lytic transglycosylase activity
C7M53_RS12430	COG0739	heme binding
C7M53_RS12430	COG1196	nuclear chromosome segregation
C7M53_RS12435	COG0741	lytic transglycosylase activity
C7M53_RS12435	COG0739	heme binding
C7M53_RS12435	COG1196	nuclear chromosome segregation
C7M53_RS12445	COG2433	Pfam Transposase IS66
C7M53_RS12455	COG5434	Belongs to the glycosyl hydrolase 28 family
C7M53_RS12460	COG5632	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS12485	COG0457	Tetratricopeptide repeat
C7M53_RS12490	COG2814	Major facilitator Superfamily
C7M53_RS12530	COG5444	nuclease activity
C7M53_RS12535	COG4282	regulation of fungal-type cell wall biogenesis
C7M53_RS12545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7M53_RS12550	COG1509	lysine 2,3-aminomutase activity
C7M53_RS12555	COG0456	acetyltransferase
C7M53_RS12560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_RS12565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7M53_RS12570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7M53_RS12575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7M53_RS12590	COG0456	acetyltransferase
C7M53_RS12595	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M53_RS12600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7M53_RS12605	COG1846	Transcriptional regulator
C7M53_RS12615	COG3706	GGDEF domain
C7M53_RS12620	COG0534	Mate efflux family protein
C7M53_RS12635	COG4698	Protein conserved in bacteria
C7M53_RS12640	COG2755	lipolytic protein G-D-S-L family
C7M53_RS12645	COG1999	signal sequence binding
C7M53_RS12660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7M53_RS12665	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M53_RS12670	COG1272	protein, Hemolysin III
C7M53_RS12675	COG0204	Acyl-transferase
C7M53_RS12680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7M53_RS12685	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M53_RS12695	COG2136	Putative SAM-dependent methyltransferase
C7M53_RS12695	COG2521	methyltransferase
C7M53_RS12705	COG0129	dihydroxy-acid dehydratase activity
C7M53_RS12710	COG1413	lyase activity
C7M53_RS12715	COG1418	mRNA catabolic process
C7M53_RS12720	COG0386	Belongs to the glutathione peroxidase family
C7M53_RS12725	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7M53_RS12730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7M53_RS12735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_RS12745	COG1278	Cold shock
C7M53_RS12765	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_RS12770	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7M53_RS12775	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_RS12785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_RS12795	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M53_RS12805	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7M53_RS12810	COG3424	synthase
C7M53_RS12815	COG0456	acetyltransferase
C7M53_RS12820	COG2233	PERMEase
C7M53_RS12825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_RS12830	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7M53_RS12835	COG1199	ATP-dependent helicase activity
C7M53_RS12845	COG0116	Belongs to the methyltransferase superfamily
C7M53_RS12855	COG3599	regulation of cell shape
C7M53_RS12860	COG4474	Belongs to the UPF0398 family
C7M53_RS12870	COG3359	exonuclease
C7M53_RS12875	COG1205	dead DEAH box helicase
C7M53_RS12875	COG1111	helicase
C7M53_RS12880	COG2190	(PTS) system
C7M53_RS12885	COG0071	Belongs to the small heat shock protein (HSP20) family
C7M53_RS12920	COG3331	DNA recombination
C7M53_RS12925	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M53_RS12925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_RS12935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7M53_RS12940	COG3935	DnaD domain protein
C7M53_RS12945	COG0017	Asparaginyl-tRNA synthetase
C7M53_RS12950	COG0436	Aminotransferase
C7M53_RS12955	COG5353	protein conserved in bacteria
C7M53_RS12965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7M53_RS12965	COG1199	ATP-dependent helicase activity
C7M53_RS12970	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C7M53_RS12975	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7M53_RS12980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7M53_RS12995	COG0617	tRNA 3'-terminal CCA addition
C7M53_RS13000	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS13005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
C7M53_RS13010	COG1803	Methylglyoxal synthase
C7M53_RS13015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7M53_RS13020	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M53_RS13025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS13035	COG4347	Protein of unknown function (DUF1405)
C7M53_RS13040	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M53_RS13040	COG2010	Cytochrome c
C7M53_RS13045	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7M53_RS13050	COG0723	plastoquinol--plastocyanin reductase activity
C7M53_RS13060	COG5582	Belongs to the UPF0302 family
C7M53_RS13065	COG0457	Tetratricopeptide repeat
C7M53_RS13070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7M53_RS13075	COG0287	Prephenate dehydrogenase
C7M53_RS13080	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7M53_RS13085	COG0159	tryptophan synthase activity
C7M53_RS13090	COG0133	tryptophan synthase activity
C7M53_RS13095	COG0135	phosphoribosylanthranilate isomerase activity
C7M53_RS13100	COG0134	indole-3-glycerol-phosphate synthase activity
C7M53_RS13105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M53_RS13110	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7M53_RS13115	COG4401	Chorismate mutase type I
C7M53_RS13120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7M53_RS13125	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7M53_RS13130	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7M53_RS13135	COG0105	UTP biosynthetic process
C7M53_RS13140	COG0142	geranyltranstransferase activity
C7M53_RS13145	COG2226	methyltransferase
C7M53_RS13150	COG0142	geranyltranstransferase activity
C7M53_RS13165	COG0776	regulation of translation
C7M53_RS13170	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
C7M53_RS13190	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7M53_RS13195	COG1160	GTP binding
C7M53_RS13220	COG1304	FMN binding
C7M53_RS13225	COG0539	negative regulation of cytoplasmic translation
C7M53_RS13230	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7M53_RS13235	COG2959	enzyme of heme biosynthesis
C7M53_RS13240	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_RS13240	COG3773	Cell wall hydrolase
C7M53_RS13245	COG2339	peptidase activity
C7M53_RS13255	COG0492	ferredoxin-NADP+ reductase activity
C7M53_RS13260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7M53_RS13265	COG4862	establishment of competence for transformation
C7M53_RS13270	COG1408	metallophosphoesterase
C7M53_RS13280	COG1388	LysM domain
C7M53_RS13285	COG1266	CAAX protease self-immunity
C7M53_RS13290	COG0514	ATP-dependent DNA helicase (RecQ)
C7M53_RS13295	COG4955	Helix-turn-helix domain
C7M53_RS13300	COG1141	Ferredoxin
C7M53_RS13305	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7M53_RS13310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7M53_RS13315	COG0739	heme binding
C7M53_RS13325	COG1595	DNA-templated transcription, initiation
C7M53_RS13330	COG1316	TRANSCRIPTIONal
C7M53_RS13345	COG5002	protein histidine kinase activity
C7M53_RS13355	COG5002	protein histidine kinase activity
C7M53_RS13360	COG0745	RESPONSE REGULATOR receiver
C7M53_RS13365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M53_RS13370	COG1333	cytochrome c biogenesis protein
C7M53_RS13375	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS13380	COG1187	pseudouridine synthase activity
C7M53_RS13385	COG0700	Nucleoside recognition
C7M53_RS13390	COG2715	membrane protein required for spore maturation
C7M53_RS13395	COG1686	Belongs to the peptidase S11 family
C7M53_RS13405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7M53_RS13410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7M53_RS13420	COG1547	Domain of unknown function (DUF309)
C7M53_RS13425	COG0456	acetyltransferase
C7M53_RS13430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7M53_RS13435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M53_RS13435	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7M53_RS13440	COG0307	riboflavin synthase, alpha
C7M53_RS13445	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M53_RS13445	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7M53_RS13470	COG0457	Tetratricopeptide repeat
C7M53_RS13475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7M53_RS13480	COG4086	secreted protein
C7M53_RS13485	COG4195	phage-related replication protein
C7M53_RS13490	COG0019	diaminopimelate decarboxylase activity
C7M53_RS13500	COG0697	spore germination
C7M53_RS13515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7M53_RS13540	COG2172	sigma factor antagonist activity
C7M53_RS13550	COG1686	Belongs to the peptidase S11 family
C7M53_RS13555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7M53_RS13560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7M53_RS13565	COG4974	Belongs to the 'phage' integrase family
C7M53_RS13575	COG0735	belongs to the Fur family
C7M53_RS13580	COG1300	Membrane
C7M53_RS13585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS13605	COG2153	protein acetylation
C7M53_RS13610	COG1379	DNA repair
C7M53_RS13615	COG0494	nUDIX hydrolase
C7M53_RS13625	COG1309	transcriptional regulator
C7M53_RS13635	COG0667	Aldo Keto reductase
C7M53_RS13645	COG1073	alpha beta
C7M53_RS13655	COG4918	Iron-sulphur cluster biosynthesis
C7M53_RS13665	COG0456	acetyltransferase
C7M53_RS13665	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M53_RS13670	COG2329	Antibiotic biosynthesis monooxygenase
C7M53_RS13680	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7M53_RS13690	COG0747	negative chemotaxis
C7M53_RS13695	COG0601	transmembrane transport
C7M53_RS13700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS13705	COG0444	Belongs to the ABC transporter superfamily
C7M53_RS13710	COG0534	Mate efflux family protein
C7M53_RS13725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M53_RS13735	COG2211	Major facilitator Superfamily
C7M53_RS13740	COG0346	lactoylglutathione lyase activity
C7M53_RS13745	COG1072	(Pantothenic acid kinase))
C7M53_RS13760	COG1131	(ABC) transporter
C7M53_RS13780	COG4195	phage-related replication protein
C7M53_RS13790	COG0300	oxidoreductase activity
C7M53_RS13795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS13800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_RS13805	COG4187	Peptidase family M20/M25/M40
C7M53_RS13810	COG1902	pentaerythritol trinitrate reductase activity
C7M53_RS13815	COG0596	Alpha beta hydrolase
C7M53_RS13820	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_RS13825	COG1234	tRNA 3'-trailer cleavage
C7M53_RS13830	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7M53_RS13845	COG2358	TRAP transporter, solute receptor (TAXI family
C7M53_RS13850	COG2188	Transcriptional regulator
C7M53_RS13855	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS13860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS13865	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_RS13870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS13875	COG1785	Belongs to the alkaline phosphatase family
C7M53_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS13885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7M53_RS13890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7M53_RS13900	COG0706	membrane insertase activity
C7M53_RS13905	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M53_RS13910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7M53_RS13915	COG4129	membrane
C7M53_RS13920	COG1126	abc transporter atp-binding protein
C7M53_RS13925	COG0765	amino acid transport
C7M53_RS13930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7M53_RS13940	COG1597	lipid kinase activity
C7M53_RS13945	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_RS13950	COG0022	dehydrogenase e1 component
C7M53_RS13955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7M53_RS13960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7M53_RS13965	COG3426	butyrate kinase activity
C7M53_RS13975	COG0280	phosphate acetyltransferase
C7M53_RS13980	COG3290	protein histidine kinase activity
C7M53_RS13980	COG3829	transcription factor binding
C7M53_RS13990	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_RS13995	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS14010	COG1045	serine acetyltransferase
C7M53_RS14020	COG0745	RESPONSE REGULATOR receiver
C7M53_RS14025	COG0750	zinc metalloprotease
C7M53_RS14030	COG0497	DNA recombination
C7M53_RS14035	COG1438	arginine binding
C7M53_RS14040	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7M53_RS14045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7M53_RS14050	COG0142	geranyltranstransferase activity
C7M53_RS14055	COG1722	exodeoxyribonuclease VII activity
C7M53_RS14060	COG1570	exodeoxyribonuclease VII activity
C7M53_RS14065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7M53_RS14070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7M53_RS14075	COG1302	Protein conserved in bacteria
C7M53_RS14080	COG0439	Biotin carboxylase
C7M53_RS14085	COG0511	ligase activity, forming carbon-carbon bonds
C7M53_RS14125	COG3854	ATPases associated with a variety of cellular activities
C7M53_RS14135	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7M53_RS14140	COG0006	proline dipeptidase activity
C7M53_RS14145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7M53_RS14155	COG3872	metal-dependent enzyme
C7M53_RS14165	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7M53_RS14170	COG1321	iron dependent repressor
C7M53_RS14175	COG0095	Lipoate-protein ligase
C7M53_RS14180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_RS14185	COG2113	Glycine betaine
C7M53_RS14190	COG4176	ABC-type proline glycine betaine transport system permease component
C7M53_RS14195	COG4175	Glycine betaine
C7M53_RS14195	COG0517	IMP dehydrogenase activity
C7M53_RS14200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M53_RS14205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7M53_RS14210	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7M53_RS14215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M53_RS14240	COG0681	Belongs to the peptidase S26 family
C7M53_RS14265	COG4940	Competence protein ComGF
C7M53_RS14275	COG4970	Tfp pilus assembly protein FimT
C7M53_RS14280	COG4537	Required for transformation and DNA binding
C7M53_RS14285	COG1459	type II secretion system
C7M53_RS14290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7M53_RS14295	COG1366	Belongs to the anti-sigma-factor antagonist family
C7M53_RS14305	COG1393	Belongs to the ArsC family
C7M53_RS14315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS14325	COG0011	TIGRFAM Protein of
C7M53_RS14335	COG2866	Carboxypeptidase
C7M53_RS14340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS14345	COG1368	sulfuric ester hydrolase activity
C7M53_RS14350	COG1940	carbohydrate kinase activity
C7M53_RS14355	COG4483	Protein conserved in bacteria
C7M53_RS14360	COG0697	spore germination
C7M53_RS14365	COG0457	Tetratricopeptide repeat
C7M53_RS14365	COG0705	Rhomboid family
C7M53_RS14370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7M53_RS14375	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7M53_RS14380	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS14395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M53_RS14400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M53_RS14405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7M53_RS14410	COG0581	inorganic phosphate transmembrane transporter activity
C7M53_RS14415	COG0573	inorganic phosphate transmembrane transporter activity
C7M53_RS14420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7M53_RS14425	COG0768	penicillin binding
C7M53_RS14430	COG0477	Major facilitator Superfamily
C7M53_RS14435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7M53_RS14440	COG2839	Protein conserved in bacteria
C7M53_RS14445	COG5521	maltodextrose utilization protein MalA
C7M53_RS14450	COG1388	LysM domain
C7M53_RS14455	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7M53_RS14460	COG4709	membrane
C7M53_RS14465	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
C7M53_RS14470	COG0735	belongs to the Fur family
C7M53_RS14475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_RS14480	COG1121	(ABC) transporter
C7M53_RS14485	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS14495	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7M53_RS14500	COG0513	Belongs to the DEAD box helicase family
C7M53_RS14510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7M53_RS14515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7M53_RS14520	COG2384	SAM-dependent methyltransferase
C7M53_RS14570	COG5444	nuclease activity
C7M53_RS14585	COG2010	Cytochrome c
C7M53_RS14590	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7M53_RS14595	COG0358	DNA primase activity
C7M53_RS14600	COG1671	Belongs to the UPF0178 family
C7M53_RS14605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7M53_RS14610	COG0517	IMP dehydrogenase activity
C7M53_RS14615	COG0751	glycine-tRNA ligase activity
C7M53_RS14620	COG0752	glycyl-tRNA synthetase alpha subunit
C7M53_RS14625	COG1381	Involved in DNA repair and RecF pathway recombination
C7M53_RS14635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7M53_RS14640	COG0295	cytidine deaminase activity
C7M53_RS14645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7M53_RS14650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7M53_RS14655	COG1480	7TM receptor with intracellular HD hydrolase
C7M53_RS14660	COG1702	phosphate starvation-inducible protein PhoH
C7M53_RS14665	COG0561	phosphatase activity
C7M53_RS14680	COG4864	UPF0365 protein
C7M53_RS14685	COG1030	water channel activity
C7M53_RS14690	COG1610	YqeY-like protein
C7M53_RS14695	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7M53_RS14700	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7M53_RS14705	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M53_RS14710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7M53_RS14715	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7M53_RS14720	COG2264	protein methyltransferase activity
C7M53_RS14725	COG0484	heat shock protein binding
C7M53_RS14730	COG0443	Heat shock 70 kDa protein
C7M53_RS14735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7M53_RS14740	COG1420	regulation of RNA biosynthetic process
C7M53_RS14745	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7M53_RS14750	COG0481	GTPase activity
C7M53_RS14765	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7M53_RS14770	COG0268	Binds directly to 16S ribosomal RNA
C7M53_RS14775	COG1466	dna polymerase III delta subunit
C7M53_RS14785	COG0658	competence protein
C7M53_RS14785	COG2333	competence protein COMEC
C7M53_RS14790	COG2131	deaminase
C7M53_RS14795	COG1555	photosystem II stabilization
C7M53_RS14795	COG1596	polysaccharide export
C7M53_RS14800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7M53_RS14805	COG2226	methyltransferase
C7M53_RS14810	COG0799	negative regulation of ribosome biogenesis
C7M53_RS14815	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7M53_RS14820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7M53_RS14825	COG1534	Rna-binding protein
C7M53_RS14830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7M53_RS14835	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7M53_RS14840	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7M53_RS14850	COG2755	lipolytic protein G-D-S-L family
C7M53_RS14855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS14860	COG5609	conserved protein (DUF2294)
C7M53_RS14865	COG3383	formate dehydrogenase (NAD+) activity
C7M53_RS14870	COG2427	Protein of unknown function (DUF1641)
C7M53_RS14910	COG0300	oxidoreductase activity
C7M53_RS14915	COG1902	pentaerythritol trinitrate reductase activity
C7M53_RS14920	COG0596	Alpha beta hydrolase
C7M53_RS14920	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7M53_RS14925	COG1309	transcriptional regulator
C7M53_RS14935	COG1063	alcohol dehydrogenase
C7M53_RS14970	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS15025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_RS15025	COG0425	Belongs to the sulfur carrier protein TusA family
C7M53_RS15035	COG2197	response regulator
C7M53_RS15040	COG4585	Histidine kinase
C7M53_RS15045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS15050	COG0730	response to heat
C7M53_RS15055	COG0425	Belongs to the sulfur carrier protein TusA family
C7M53_RS15060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS15060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_RS15065	COG0425	Belongs to the sulfur carrier protein TusA family
C7M53_RS15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_RS15070	COG2210	Belongs to the sulfur carrier protein TusA family
C7M53_RS15075	COG1937	Protein conserved in bacteria
C7M53_RS15120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M53_RS15125	COG0113	porphobilinogen synthase activity
C7M53_RS15130	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_RS15135	COG1121	(ABC) transporter
C7M53_RS15140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_RS15160	COG1942	4-Oxalocrotonate Tautomerase
C7M53_RS15170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7M53_RS15180	COG1733	regulation of RNA biosynthetic process
C7M53_RS15185	COG3239	Fatty acid desaturase
C7M53_RS15190	COG4585	Histidine kinase
C7M53_RS15195	COG2197	response regulator
C7M53_RS15200	COG0492	ferredoxin-NADP+ reductase activity
C7M53_RS15205	COG0747	negative chemotaxis
C7M53_RS15210	COG0601	transmembrane transport
C7M53_RS15215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7M53_RS15220	COG0444	Belongs to the ABC transporter superfamily
C7M53_RS15225	COG4608	Belongs to the ABC transporter superfamily
C7M53_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS15260	COG2124	cytochrome p450
C7M53_RS15265	COG0730	response to heat
C7M53_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS15285	COG1621	beta-fructofuranosidase activity
C7M53_RS15290	COG3716	PTS system mannose fructose sorbose family IID component
C7M53_RS15295	COG3715	PTS system
C7M53_RS15300	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS15305	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS15310	COG3933	PFAM sigma-54 factor interaction domain-containing protein
C7M53_RS15310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7M53_RS15330	COG2169	Transcriptional regulator
C7M53_RS15335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7M53_RS15340	COG0656	L-ascorbic acid biosynthetic process
C7M53_RS15345	COG2814	Major facilitator Superfamily
C7M53_RS15350	COG1733	regulation of RNA biosynthetic process
C7M53_RS15355	COG3340	Belongs to the peptidase S51 family
C7M53_RS15360	COG1587	Uroporphyrinogen-III synthase
C7M53_RS15370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS15375	COG0583	DNA-binding transcription factor activity
C7M53_RS15380	COG2814	Major facilitator Superfamily
C7M53_RS15390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7M53_RS15390	COG2124	cytochrome p450
C7M53_RS15395	COG1309	transcriptional regulator
C7M53_RS15400	COG1404	Belongs to the peptidase S8 family
C7M53_RS15405	COG2226	methyltransferase
C7M53_RS15430	COG0626	cystathionine gamma-synthase activity
C7M53_RS15435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_RS15440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7M53_RS15445	COG2226	methyltransferase
C7M53_RS15460	COG0768	penicillin binding
C7M53_RS15465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7M53_RS15470	COG0572	uridine kinase
C7M53_RS15475	COG0826	peptidase U32
C7M53_RS15480	COG0826	peptidase U32
C7M53_RS15485	COG4122	O-methyltransferase activity
C7M53_RS15490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7M53_RS15495	COG3906	Belongs to the UPF0473 family
C7M53_RS15500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7M53_RS15505	COG4472	Bacterial protein of unknown function (DUF965)
C7M53_RS15510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7M53_RS15515	COG0628	permease
C7M53_RS15530	COG3881	PFAM PRC-barrel domain
C7M53_RS15535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7M53_RS15540	COG0457	Tetratricopeptide repeat
C7M53_RS15545	COG0482	sulfurtransferase activity
C7M53_RS15550	COG1104	cysteine desulfurase activity
C7M53_RS15555	COG1959	2 iron, 2 sulfur cluster binding
C7M53_RS15560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7M53_RS15565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7M53_RS15575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7M53_RS15580	COG0124	histidyl-tRNA synthetase
C7M53_RS15585	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS15585	COG4991	sh3 domain protein
C7M53_RS15585	COG3103	Sh3 type 3 domain protein
C7M53_RS15590	COG1490	D-aminoacyl-tRNA deacylase activity
C7M53_RS15595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7M53_RS15600	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7M53_RS15605	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7M53_RS15605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7M53_RS15610	COG5416	Lipopolysaccharide assembly protein A domain
C7M53_RS15615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M53_RS15615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7M53_RS15625	COG2244	polysaccharide biosynthetic process
C7M53_RS15630	COG2323	membrane
C7M53_RS15640	COG1862	Preprotein translocase
C7M53_RS15645	COG0343	queuine tRNA-ribosyltransferase activity
C7M53_RS15650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7M53_RS15660	COG2255	four-way junction helicase activity
C7M53_RS15665	COG0632	four-way junction helicase activity
C7M53_RS15675	COG2112	serine threonine protein kinase
C7M53_RS15690	COG2318	DinB family
C7M53_RS15695	COG4195	phage-related replication protein
C7M53_RS15710	COG0217	transcriptional regulatory protein
C7M53_RS15720	COG1388	LysM domain
C7M53_RS15725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7M53_RS15730	COG0157	Belongs to the NadC ModD family
C7M53_RS15735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7M53_RS15740	COG1104	cysteine desulfurase activity
C7M53_RS15745	COG1827	regulation of RNA biosynthetic process
C7M53_RS15750	COG0077	Prephenate dehydratase
C7M53_RS15755	COG4492	Belongs to the UPF0735 family
C7M53_RS15760	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7M53_RS15765	COG3290	protein histidine kinase activity
C7M53_RS15770	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7M53_RS15775	COG2868	ribosomal protein
C7M53_RS15780	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7M53_RS15785	COG1994	Peptidase M50
C7M53_RS15790	COG0739	heme binding
C7M53_RS15795	COG3832	glyoxalase III activity
C7M53_RS15800	COG0640	Transcriptional regulator
C7M53_RS15805	COG2894	cell division
C7M53_RS15810	COG0850	regulation of cytokinetic process
C7M53_RS15815	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7M53_RS15825	COG1077	Cell shape determining protein MreB Mrl
C7M53_RS15830	COG2003	Belongs to the UPF0758 family
C7M53_RS15835	COG0424	maF-like protein
C7M53_RS15845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C7M53_RS15850	COG0285	dihydrofolate synthase activity
C7M53_RS15855	COG0525	valine-tRNA ligase activity
C7M53_RS15865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M53_RS15870	COG1388	LysM domain
C7M53_RS15875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7M53_RS15880	COG0113	porphobilinogen synthase activity
C7M53_RS15885	COG1587	Uroporphyrinogen-III synthase
C7M53_RS15890	COG0181	hydroxymethylbilane synthase activity
C7M53_RS15895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7M53_RS15900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7M53_RS15910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7M53_RS15915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7M53_RS15920	COG1067	ATP-dependent peptidase activity
C7M53_RS15920	COG0470	DNA polymerase III
C7M53_RS15925	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7M53_RS15930	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7M53_RS15935	COG0457	Tetratricopeptide repeat
C7M53_RS15935	COG1477	protein flavinylation
C7M53_RS15940	COG0066	3-isopropylmalate dehydratase activity
C7M53_RS15945	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7M53_RS15950	COG0473	3-isopropylmalate dehydrogenase activity
C7M53_RS15955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7M53_RS15960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7M53_RS15965	COG0440	acetolactate synthase activity
C7M53_RS15970	COG0028	Belongs to the TPP enzyme family
C7M53_RS15975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_RS16005	COG5518	Phage portal protein
C7M53_RS16060	COG5444	nuclease activity
C7M53_RS16065	COG0457	Tetratricopeptide repeat
C7M53_RS16085	COG0622	Phosphoesterase
C7M53_RS16090	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7M53_RS16095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7M53_RS16100	COG5401	PFAM Sporulation and spore germination
C7M53_RS16105	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7M53_RS16110	COG1846	Transcriptional regulator
C7M53_RS16115	COG2197	response regulator
C7M53_RS16120	COG4221	oxidoreductase activity
C7M53_RS16125	COG0824	Thioesterase
C7M53_RS16130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7M53_RS16135	COG1053	succinate dehydrogenase
C7M53_RS16140	COG2009	succinate dehydrogenase
C7M53_RS16145	COG1719	4-vinyl reductase, 4VR
C7M53_RS16150	COG0527	aspartate kinase activity
C7M53_RS16160	COG0322	excinuclease ABC activity
C7M53_RS16165	COG3118	belongs to the thioredoxin family
C7M53_RS16170	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
C7M53_RS16175	COG2086	electron transfer activity
C7M53_RS16180	COG1024	Enoyl-CoA hydratase
C7M53_RS16185	COG1309	transcriptional regulator
C7M53_RS16190	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS16195	COG3766	membrane
C7M53_RS16200	COG1193	negative regulation of DNA recombination
C7M53_RS16205	COG1796	DNA polymerase
C7M53_RS16205	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M53_RS16210	COG1286	toxin biosynthetic process
C7M53_RS16215	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7M53_RS16220	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7M53_RS16245	COG1137	ATPase activity
C7M53_RS16260	COG0072	phenylalanine-tRNA ligase activity
C7M53_RS16260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_RS16265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7M53_RS16270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7M53_RS16280	COG1966	Carbon starvation protein
C7M53_RS16295	COG0395	ABC-type sugar transport system, permease component
C7M53_RS16300	COG1175	transmembrane transport
C7M53_RS16305	COG1653	transport
C7M53_RS16310	COG0371	Dehydrogenase
C7M53_RS16315	COG0235	Class ii aldolase
C7M53_RS16320	COG1069	ribulokinase activity
C7M53_RS16325	COG2160	L-arabinose isomerase activity
C7M53_RS16330	COG3507	Belongs to the glycosyl hydrolase 43 family
C7M53_RS16335	COG1363	Peptidase, m42
C7M53_RS16345	COG3326	Membrane
C7M53_RS16350	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7M53_RS16355	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7M53_RS16360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7M53_RS16365	COG1346	cytolysis
C7M53_RS16375	COG3540	Alkaline phosphatase
C7M53_RS16380	COG3279	Response regulator of the LytR AlgR family
C7M53_RS16385	COG3275	phosphorelay sensor kinase activity
C7M53_RS16395	COG1011	Hydrolase
C7M53_RS16400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7M53_RS16410	COG0398	Pfam SNARE associated Golgi protein
C7M53_RS16415	COG1484	DNA-dependent DNA replication
C7M53_RS16420	COG3611	Membrane attachment protein
C7M53_RS16425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7M53_RS16440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
C7M53_RS16445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M53_RS16450	COG3866	Pectate lyase
C7M53_RS16455	COG0237	dephospho-CoA kinase activity
C7M53_RS16460	COG1971	Probably functions as a manganese efflux pump
C7M53_RS16465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7M53_RS16470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_RS16470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7M53_RS16475	COG5002	protein histidine kinase activity
C7M53_RS16480	COG0745	RESPONSE REGULATOR receiver
C7M53_RS16485	COG0039	L-malate dehydrogenase activity
C7M53_RS16490	COG0538	isocitrate dehydrogenase activity
C7M53_RS16495	COG0372	Belongs to the citrate synthase family
C7M53_RS16500	COG2707	UPF0756 membrane protein
C7M53_RS16505	COG0628	permease
C7M53_RS16510	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7M53_RS16520	COG0205	6-phosphofructokinase activity
C7M53_RS16525	COG0825	malonyl-CoA metabolic process
C7M53_RS16530	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7M53_RS16535	COG0281	malic enzyme
C7M53_RS16540	COG0587	DNA-directed DNA polymerase activity
C7M53_RS16560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7M53_RS16570	COG4109	DRTGG domain
C7M53_RS16575	COG1695	Transcriptional regulator
C7M53_RS16580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M53_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS16590	COG0165	Argininosuccinate lyase
C7M53_RS16595	COG0137	argininosuccinate synthase activity
C7M53_RS16600	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7M53_RS16605	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7M53_RS16610	COG0827	DNA restriction-modification system
C7M53_RS16615	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
C7M53_RS16620	COG3874	Sporulation protein YtfJ
C7M53_RS16630	COG1714	RDD family
C7M53_RS16635	COG0616	signal peptide processing
C7M53_RS16640	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7M53_RS16645	COG1566	PFAM secretion protein HlyD family protein
C7M53_RS16660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_RS16670	COG0301	tRNA thio-modification
C7M53_RS16675	COG1104	cysteine desulfurase activity
C7M53_RS16680	COG1114	Component of the transport system for branched-chain amino acids
C7M53_RS16690	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
C7M53_RS16695	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7M53_RS16700	COG1309	transcriptional regulator
C7M53_RS16705	COG1956	GAF domain-containing protein
C7M53_RS16710	COG2199	diguanylate cyclase activity
C7M53_RS16710	COG2203	Gaf domain
C7M53_RS16715	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7M53_RS16730	COG3152	Membrane
C7M53_RS16735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7M53_RS16740	COG1522	sequence-specific DNA binding
C7M53_RS16745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7M53_RS16750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7M53_RS16755	COG0454	-acetyltransferase
C7M53_RS16760	COG0517	IMP dehydrogenase activity
C7M53_RS16765	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7M53_RS16770	COG1360	Flagellar Motor Protein
C7M53_RS16775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7M53_RS16780	COG1609	Transcriptional regulator
C7M53_RS16785	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7M53_RS16785	COG1605	Chorismate mutase
C7M53_RS16795	COG3118	belongs to the thioredoxin family
C7M53_RS16800	COG4980	gas vesicle protein
C7M53_RS16805	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
C7M53_RS16810	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7M53_RS16815	COG1674	ftsk spoiiie
C7M53_RS16820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7M53_RS16825	COG4848	Belongs to the UPF0354 family
C7M53_RS16830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS16840	COG1363	Peptidase, m42
C7M53_RS16845	COG5584	Small secreted protein
C7M53_RS16850	COG0281	malic enzyme
C7M53_RS16855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7M53_RS16860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7M53_RS16870	COG0510	thiamine kinase activity
C7M53_RS16875	COG1523	belongs to the glycosyl hydrolase 13 family
C7M53_RS16880	COG1597	lipid kinase activity
C7M53_RS16890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
C7M53_RS16895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7M53_RS16910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_RS16915	COG2252	PERMEase
C7M53_RS16920	COG1349	DNA-binding transcription factor activity
C7M53_RS16925	COG1187	pseudouridine synthase activity
C7M53_RS16930	COG2244	polysaccharide biosynthetic process
C7M53_RS16935	COG2081	HI0933 family
C7M53_RS16940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7M53_RS16955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7M53_RS16960	COG0457	Tetratricopeptide repeat
C7M53_RS16970	COG5578	integral membrane protein
C7M53_RS16975	COG0673	inositol 2-dehydrogenase activity
C7M53_RS16980	COG1653	transport
C7M53_RS16985	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7M53_RS16990	COG4209	transmembrane transport
C7M53_RS16995	COG2207	Transcriptional regulator
C7M53_RS17000	COG1653	transport
C7M53_RS17005	COG0395	ABC-type sugar transport system, permease component
C7M53_RS17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_RS17015	COG1073	alpha beta
C7M53_RS17025	COG0583	DNA-binding transcription factor activity
C7M53_RS17030	COG0346	lactoylglutathione lyase activity
C7M53_RS17035	COG0495	leucyl-tRNA aminoacylation
C7M53_RS17045	COG2814	Major facilitator Superfamily
C7M53_RS17055	COG2433	Pfam Transposase IS66
C7M53_RS17060	COG0577	efflux transmembrane transporter activity
C7M53_RS17065	COG1136	(ABC) transporter
C7M53_RS17075	COG1131	(ABC) transporter
C7M53_RS17080	COG1725	Transcriptional regulator
C7M53_RS17090	COG1242	4 iron, 4 sulfur cluster binding
C7M53_RS17095	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7M53_RS17100	COG1301	dicarboxylic acid transport
C7M53_RS17110	COG2267	carboxylic ester hydrolase activity
C7M53_RS17115	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7M53_RS17120	COG0671	phosphoesterase, PA-phosphatase related
C7M53_RS17125	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_RS17125	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS17130	COG0367	asparagine synthase
C7M53_RS17135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7M53_RS17140	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7M53_RS17155	COG1506	peptidase
C7M53_RS17160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7M53_RS17165	COG1116	anion transmembrane transporter activity
C7M53_RS17170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7M53_RS17175	COG0494	nUDIX hydrolase
C7M53_RS17185	COG4824	toxin secretion phage lysis holin
C7M53_RS17190	COG0783	Belongs to the Dps family
C7M53_RS17205	COG1854	S-ribosylhomocysteine lyase activity
C7M53_RS17210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7M53_RS17215	COG0288	reversible hydration of carbon dioxide
C7M53_RS17220	COG0523	cobalamin synthesis protein
C7M53_RS17225	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_RS17230	COG0254	rRNA binding
C7M53_RS17235	COG1271	oxidase subunit
C7M53_RS17240	COG1294	oxidase, subunit
C7M53_RS17255	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_RS17260	COG0318	PFAM AMP-dependent synthetase and ligase
C7M53_RS17265	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7M53_RS17270	COG0596	Alpha beta hydrolase
C7M53_RS17275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7M53_RS17280	COG1169	isochorismate synthase
C7M53_RS17285	COG1575	Belongs to the MenA family. Type 1 subfamily
C7M53_RS17290	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7M53_RS17295	COG0058	SHG alpha-glucan phosphorylase activity
C7M53_RS17300	COG0297	glycogen (starch) synthase activity
C7M53_RS17305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M53_RS17310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7M53_RS17315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7M53_RS17440	COG1609	Transcriptional regulator
C7M53_RS17445	COG3859	Proton-coupled thiamine transporter YuaJ
C7M53_RS17450	COG3764	Sortase (surface protein transpeptidase)
C7M53_RS17465	COG0457	Tetratricopeptide repeat
C7M53_RS17470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7M53_RS17475	COG0569	domain protein
C7M53_RS17480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_RS17490	COG2318	DinB family
C7M53_RS17500	COG1454	alcohol dehydrogenase
C7M53_RS17505	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS17510	COG1510	regulation of RNA biosynthetic process
C7M53_RS17520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7M53_RS17525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7M53_RS17530	COG2140	Oxalate decarboxylase
C7M53_RS17570	COG1397	ADP-ribosylglycohydrolase
C7M53_RS17605	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
C7M53_RS17615	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7M53_RS17620	COG0726	polysaccharide deacetylase
C7M53_RS17625	COG1408	metallophosphoesterase
C7M53_RS17630	COG1968	undecaprenyl-diphosphatase activity
C7M53_RS17635	COG0628	permease
C7M53_RS17640	COG0673	inositol 2-dehydrogenase activity
C7M53_RS17645	COG0693	protein deglycase activity
C7M53_RS17650	COG0840	transmembrane signaling receptor activity
C7M53_RS17655	COG0840	transmembrane signaling receptor activity
C7M53_RS17660	COG0840	transmembrane signaling receptor activity
C7M53_RS17670	COG2070	2-Nitropropane dioxygenase
C7M53_RS17675	COG0432	Pfam Uncharacterised protein family UPF0047
C7M53_RS17680	COG0366	Alpha amylase catalytic
C7M53_RS17695	COG5297	Belongs to the glycosyl hydrolase family 6
C7M53_RS17700	COG1253	flavin adenine dinucleotide binding
C7M53_RS17705	COG2738	Putative neutral zinc metallopeptidase
C7M53_RS17715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7M53_RS17725	COG2323	membrane
C7M53_RS17730	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
C7M53_RS17740	COG0166	Belongs to the GPI family
C7M53_RS17745	COG1979	alcohol dehydrogenase
C7M53_RS17750	COG2155	Conserved Protein
C7M53_RS17755	COG1098	S1 RNA binding domain
C7M53_RS17760	COG0436	Aminotransferase
C7M53_RS17765	COG1522	sequence-specific DNA binding
C7M53_RS17770	COG2267	carboxylic ester hydrolase activity
C7M53_RS17785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7M53_RS17800	COG5018	Exonuclease
C7M53_RS17810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_RS17815	COG3011	Protein conserved in bacteria
C7M53_RS17825	COG3290	protein histidine kinase activity
C7M53_RS17830	COG4565	transcriptional regulatory protein
C7M53_RS17840	COG1183	phosphatidylcholine synthase activity
C7M53_RS17845	COG0586	Pfam SNARE associated Golgi protein
C7M53_RS17850	COG0688	phosphatidylethanolamine metabolic process
C7M53_RS17855	COG3493	citrate carrier protein
C7M53_RS17865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7M53_RS17865	COG2111	Na H antiporter
C7M53_RS17870	COG2111	Na H antiporter
C7M53_RS17875	COG1006	Multisubunit Na H antiporter MnhC subunit
C7M53_RS17880	COG0651	ATP synthesis coupled electron transport
C7M53_RS17885	COG1863	multisubunit Na H antiporter MnhE subunit
C7M53_RS17890	COG2212	antiporter activity
C7M53_RS17895	COG1320	monovalent cation:proton antiporter activity
C7M53_RS17900	COG2050	protein possibly involved in aromatic compounds catabolism
C7M53_RS17905	COG2197	response regulator
C7M53_RS17910	COG4585	Histidine kinase
C7M53_RS17940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7M53_RS17945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7M53_RS17950	COG1335	isochorismatase
C7M53_RS17955	COG5506	Protein of unknown function (DUF1694)
C7M53_RS17970	COG0628	permease
C7M53_RS17975	COG1959	2 iron, 2 sulfur cluster binding
C7M53_RS17980	COG0657	acetylesterase activity
C7M53_RS17990	COG1418	mRNA catabolic process
C7M53_RS17995	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS18005	COG1511	domain protein
C7M53_RS18010	COG0433	COG0433 Predicted ATPase
C7M53_RS18010	COG1674	ftsk spoiiie
C7M53_RS18015	COG4499	WXG100 protein secretion system (Wss), protein YukC
C7M53_RS18020	COG5417	Belongs to the EsaB family
C7M53_RS18025	COG4842	Belongs to the WXG100 family
C7M53_RS18030	COG1115	amino acid carrier protein
C7M53_RS18035	COG2508	Transcriptional regulator
C7M53_RS18035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7M53_RS18040	COG0686	Belongs to the AlaDH PNT family
C7M53_RS18050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7M53_RS18055	COG1268	BioY protein
C7M53_RS18060	COG2056	Na+-H+ antiporter family
C7M53_RS18065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7M53_RS18070	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
C7M53_RS18075	COG3584	3D domain protein
C7M53_RS18085	COG1252	NADH dehydrogenase
C7M53_RS18090	COG0492	ferredoxin-NADP+ reductase activity
C7M53_RS18105	COG0456	acetyltransferase
C7M53_RS18110	COG0316	Belongs to the HesB IscA family
C7M53_RS18115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7M53_RS18120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_RS18125	COG4844	belongs to the
C7M53_RS18130	COG1252	NADH dehydrogenase
C7M53_RS18135	COG5646	InterPro IPR014922
C7M53_RS18145	COG0457	Tetratricopeptide repeat
C7M53_RS18150	COG3479	Phenolic acid decarboxylase
C7M53_RS18160	COG4837	Protein of unknown function (DUF1462)
C7M53_RS18165	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7M53_RS18170	COG4946	Tricorn protease homolog
C7M53_RS18170	COG1506	peptidase
C7M53_RS18170	COG0823	Involved in the tonB-independent uptake of proteins
C7M53_RS18175	COG0083	homoserine kinase activity
C7M53_RS18180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7M53_RS18185	COG0460	homoserine dehydrogenase
C7M53_RS18195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7M53_RS18200	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7M53_RS18205	COG0647	UMP catabolic process
C7M53_RS18210	COG2445	Protein of unknown function DUF86
C7M53_RS18215	COG4470	Protein conserved in bacteria
C7M53_RS18230	COG0739	heme binding
C7M53_RS18240	COG0733	neurotransmitter:sodium symporter activity
C7M53_RS18250	COG3377	Domain of unknown function (DUF1805)
C7M53_RS18255	COG0737	Belongs to the 5'-nucleotidase family
C7M53_RS18260	COG0730	response to heat
C7M53_RS18265	COG1801	Protein of unknown function DUF72
C7M53_RS18275	COG3226	Transcriptional regulator
C7M53_RS18285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7M53_RS18290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7M53_RS18295	COG2508	Transcriptional regulator
C7M53_RS18300	COG2814	Major facilitator Superfamily
C7M53_RS18315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7M53_RS18320	COG2356	endonuclease I
C7M53_RS18330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7M53_RS18345	COG0457	Tetratricopeptide repeat
C7M53_RS18350	COG0719	Fe-S assembly protein
C7M53_RS18355	COG0822	iron-sulfur transferase activity
C7M53_RS18360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7M53_RS18365	COG0719	Fe-S assembly protein
C7M53_RS18370	COG0396	ATPase activity
C7M53_RS18380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M53_RS18390	COG1464	Belongs to the NlpA lipoprotein family
C7M53_RS18395	COG2011	ABC-type metal ion transport system permease component
C7M53_RS18400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7M53_RS18410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7M53_RS18415	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
C7M53_RS18425	COG0509	glycine decarboxylation via glycine cleavage system
C7M53_RS18430	COG1393	Belongs to the ArsC family
C7M53_RS18435	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS18440	COG0183	Belongs to the thiolase family
C7M53_RS18445	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M53_RS18445	COG1024	Enoyl-CoA hydratase
C7M53_RS18460	COG5577	PFAM Coat F domain
C7M53_RS18475	COG1120	ATPase activity
C7M53_RS18480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS18485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS18490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS18505	COG1686	Belongs to the peptidase S11 family
C7M53_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS18515	COG0783	Belongs to the Dps family
C7M53_RS18520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_RS18525	COG0745	RESPONSE REGULATOR receiver
C7M53_RS18530	COG2770	Histidine kinase
C7M53_RS18530	COG2205	protein histidine kinase activity
C7M53_RS18535	COG1309	transcriptional regulator
C7M53_RS18540	COG0114	fumarate hydratase activity
C7M53_RS18550	COG0697	spore germination
C7M53_RS18555	COG0814	amino acid
C7M53_RS18570	COG2197	response regulator
C7M53_RS18575	COG4585	Histidine kinase
C7M53_RS18580	COG4758	membrane
C7M53_RS18590	COG1842	Phage shock protein A
C7M53_RS18595	COG4758	membrane
C7M53_RS18600	COG4677	pectinesterase activity
C7M53_RS18605	COG2096	Adenosyltransferase
C7M53_RS18610	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS18620	COG1454	alcohol dehydrogenase
C7M53_RS18625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_RS18630	COG1120	ATPase activity
C7M53_RS18635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS18640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS18645	COG1802	Transcriptional regulator
C7M53_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS18655	COG2258	MOSC domain
C7M53_RS18660	COG0583	DNA-binding transcription factor activity
C7M53_RS18670	COG2721	sulfolactate sulfo-lyase activity
C7M53_RS18675	COG0246	Mannitol dehydrogenase
C7M53_RS18680	COG1609	Transcriptional regulator
C7M53_RS18685	COG2211	Major facilitator Superfamily
C7M53_RS18690	COG1904	glucuronate isomerase
C7M53_RS18695	COG2205	protein histidine kinase activity
C7M53_RS18700	COG0745	RESPONSE REGULATOR receiver
C7M53_RS18705	COG1120	ATPase activity
C7M53_RS18710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS18715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS18720	COG0531	amino acid
C7M53_RS18730	COG1988	membrane-bound metal-dependent
C7M53_RS18735	COG1368	sulfuric ester hydrolase activity
C7M53_RS18740	COG2814	Major facilitator Superfamily
C7M53_RS18745	COG0656	L-ascorbic acid biosynthetic process
C7M53_RS18750	COG1940	carbohydrate kinase activity
C7M53_RS18765	COG3973	AAA domain
C7M53_RS18770	COG2860	membrane
C7M53_RS18775	COG0456	acetyltransferase
C7M53_RS18775	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7M53_RS18780	COG0456	acetyltransferase
C7M53_RS18785	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7M53_RS18790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7M53_RS18795	COG2217	Heavy metal translocating P-type atpase
C7M53_RS18800	COG1653	transport
C7M53_RS18805	COG1175	transmembrane transport
C7M53_RS18810	COG0395	ABC-type sugar transport system, permease component
C7M53_RS18815	COG1501	Belongs to the glycosyl hydrolase 31 family
C7M53_RS18820	COG1472	Belongs to the glycosyl hydrolase 3 family
C7M53_RS18825	COG1121	(ABC) transporter
C7M53_RS18830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7M53_RS18835	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7M53_RS18850	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M53_RS18850	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C7M53_RS18855	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS18855	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7M53_RS18855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS18870	COG2217	Heavy metal translocating P-type atpase
C7M53_RS18875	COG2608	mercury ion transmembrane transporter activity
C7M53_RS18880	COG1937	Protein conserved in bacteria
C7M53_RS18885	COG0693	protein deglycase activity
C7M53_RS18890	COG1349	DNA-binding transcription factor activity
C7M53_RS18895	COG1070	Carbohydrate kinase
C7M53_RS18900	COG4952	isomerase
C7M53_RS18910	COG3347	Dehydrogenase
C7M53_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS18915	COG2814	Major facilitator Superfamily
C7M53_RS18920	COG2814	Major facilitator Superfamily
C7M53_RS18930	COG2124	cytochrome p450
C7M53_RS18940	COG1846	Transcriptional regulator
C7M53_RS18950	COG0673	inositol 2-dehydrogenase activity
C7M53_RS18955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7M53_RS18960	COG1054	Belongs to the UPF0176 family
C7M53_RS18970	COG1191	sigma factor activity
C7M53_RS18980	COG2140	Oxalate decarboxylase
C7M53_RS19025	COG2323	membrane
C7M53_RS19030	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
C7M53_RS19035	COG0662	Cupin 2, conserved barrel domain protein
C7M53_RS19075	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M53_RS19085	COG5280	Phage tail tape measure protein TP901
C7M53_RS19085	COG3953	SLT domain
C7M53_RS19145	COG1802	Transcriptional regulator
C7M53_RS19145	COG4626	Terminase
C7M53_RS19285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7M53_RS19290	COG0557	exoribonuclease II activity
C7M53_RS19295	COG1647	Serine aminopeptidase, S33
C7M53_RS19300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7M53_RS19305	COG2002	toxin-antitoxin pair type II binding
C7M53_RS19310	COG1476	TRANSCRIPTIONal
C7M53_RS19315	COG1396	sequence-specific DNA binding
C7M53_RS19320	COG1396	sequence-specific DNA binding
C7M53_RS19325	COG1174	glycine betaine transport
C7M53_RS19330	COG1732	Glycine betaine
C7M53_RS19335	COG1174	glycine betaine transport
C7M53_RS19345	COG1510	regulation of RNA biosynthetic process
C7M53_RS19350	COG2095	MarC family integral membrane protein
C7M53_RS19355	COG3064	Membrane
C7M53_RS19365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS19385	COG0148	phosphopyruvate hydratase activity
C7M53_RS19390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7M53_RS19395	COG0149	triose-phosphate isomerase activity
C7M53_RS19400	COG0126	phosphoglycerate kinase activity
C7M53_RS19410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7M53_RS19415	COG2390	Transcriptional regulator
C7M53_RS19420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_RS19425	COG1113	amino acid transport
C7M53_RS19445	COG1556	Lactate utilization protein
C7M53_RS19450	COG1139	Iron-sulfur cluster binding protein
C7M53_RS19455	COG0247	lactate metabolic process
C7M53_RS19460	COG2186	Transcriptional regulator
C7M53_RS19465	COG1620	l-lactate permease
C7M53_RS19470	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C7M53_RS19480	COG5039	Polysaccharide pyruvyl transferase
C7M53_RS19485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_RS19490	COG0110	maltose O-acetyltransferase activity
C7M53_RS19495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7M53_RS19500	COG2244	polysaccharide biosynthetic process
C7M53_RS19505	COG1216	Glycosyl transferase, family 2
C7M53_RS19510	COG5039	Polysaccharide pyruvyl transferase
C7M53_RS19515	COG1216	Glycosyl transferase, family 2
C7M53_RS19525	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS19530	COG1215	transferase activity, transferring glycosyl groups
C7M53_RS19535	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS19540	COG1086	Polysaccharide biosynthesis protein
C7M53_RS19545	COG0489	protein tyrosine kinase activity
C7M53_RS19550	COG3944	biosynthesis protein
C7M53_RS19555	COG1396	sequence-specific DNA binding
C7M53_RS19560	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7M53_RS19565	COG2271	Major facilitator Superfamily
C7M53_RS19575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7M53_RS19590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7M53_RS19600	COG1733	regulation of RNA biosynthetic process
C7M53_RS19605	COG1902	pentaerythritol trinitrate reductase activity
C7M53_RS19610	COG1621	beta-fructofuranosidase activity
C7M53_RS19615	COG1621	beta-fructofuranosidase activity
C7M53_RS19630	COG0740	serine-type endopeptidase activity
C7M53_RS19635	COG1611	Belongs to the LOG family
C7M53_RS19640	COG1694	Mazg nucleotide pyrophosphohydrolase
C7M53_RS19645	COG1078	dGTPase activity
C7M53_RS19650	COG0659	secondary active sulfate transmembrane transporter activity
C7M53_RS19655	COG0288	reversible hydration of carbon dioxide
C7M53_RS19660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_RS19665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7M53_RS19670	COG0640	Transcriptional regulator
C7M53_RS19680	COG2732	(Barnase) inhibitor
C7M53_RS19685	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7M53_RS19690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS19695	COG1481	regulation of sporulation
C7M53_RS19700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7M53_RS19705	COG1660	Displays ATPase and GTPase activities
C7M53_RS19710	COG1051	belongs to the nudix hydrolase family
C7M53_RS19720	COG0492	ferredoxin-NADP+ reductase activity
C7M53_RS19725	COG0457	Tetratricopeptide repeat
C7M53_RS19730	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7M53_RS19735	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7M53_RS19735	COG0140	phosphoribosyl-ATP diphosphatase activity
C7M53_RS19740	COG0107	imidazoleglycerol-phosphate synthase activity
C7M53_RS19745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7M53_RS19750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7M53_RS19755	COG0131	Imidazoleglycerol-phosphate dehydratase
C7M53_RS19760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7M53_RS19765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7M53_RS19770	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C7M53_RS19775	COG4990	cell redox homeostasis
C7M53_RS19780	COG5297	Belongs to the glycosyl hydrolase family 6
C7M53_RS19785	COG0110	maltose O-acetyltransferase activity
C7M53_RS19790	COG0546	phosphoglycolate phosphatase activity
C7M53_RS19795	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
C7M53_RS19800	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7M53_RS19805	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C7M53_RS19810	COG1846	Transcriptional regulator
C7M53_RS19815	COG2814	Major facilitator Superfamily
C7M53_RS19820	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7M53_RS19825	COG1950	PFAM Membrane protein of
C7M53_RS19830	COG1983	PspC domain protein
C7M53_RS19835	COG3595	metallopeptidase activity
C7M53_RS19860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7M53_RS19865	COG0556	nucleotide-excision repair
C7M53_RS19870	COG4897	Protein conserved in bacteria
C7M53_RS19880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_RS19890	COG0793	Belongs to the peptidase S41A family
C7M53_RS19890	COG3409	Peptidoglycan-binding domain 1 protein
C7M53_RS19895	COG0473	3-isopropylmalate dehydrogenase activity
C7M53_RS19900	COG0791	NLP P60 protein
C7M53_RS19900	COG3883	PFAM NLP P60 protein
C7M53_RS19905	COG2177	Part of the ABC transporter FtsEX involved in
C7M53_RS19910	COG2884	Cell division ATP-binding protein ftsE
C7M53_RS19920	COG2010	Cytochrome c
C7M53_RS19925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS19935	COG0653	protein targeting
C7M53_RS19940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7M53_RS19955	COG1516	flagellar protein fliS
C7M53_RS19960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7M53_RS19965	COG1334	flagellar protein FlaG
C7M53_RS19975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M53_RS19980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7M53_RS19985	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
C7M53_RS19995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7M53_RS20000	COG1256	bacterial-type flagellum assembly
C7M53_RS20000	COG4786	Flagellar basal body rod
C7M53_RS20005	COG3418	PFAM FlgN family protein
C7M53_RS20010	COG2747	anti-sigma28 factor FlgM
C7M53_RS20020	COG1040	competence protein
C7M53_RS20030	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7M53_RS20035	COG1307	EDD domain protein, DegV family
C7M53_RS20040	COG2197	response regulator
C7M53_RS20045	COG4585	Histidine kinase
C7M53_RS20050	COG1739	Uncharacterized protein family UPF0029
C7M53_RS20055	COG1316	TRANSCRIPTIONal
C7M53_RS20065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7M53_RS20070	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS20075	COG1215	transferase activity, transferring glycosyl groups
C7M53_RS20080	COG3206	protein involved in exopolysaccharide biosynthesis
C7M53_RS20085	COG3307	-O-antigen
C7M53_RS20090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7M53_RS20095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
C7M53_RS20100	COG0438	transferase activity, transferring glycosyl groups
C7M53_RS20100	COG0297	glycogen (starch) synthase activity
C7M53_RS20105	COG2244	polysaccharide biosynthetic process
C7M53_RS20115	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7M53_RS20115	COG2247	cell wall binding repeat
C7M53_RS20120	COG2385	sporulation resulting in formation of a cellular spore
C7M53_RS20120	COG2247	cell wall binding repeat
C7M53_RS20130	COG1316	TRANSCRIPTIONal
C7M53_RS20135	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C7M53_RS20140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7M53_RS20145	COG1134	teichoic acid transport
C7M53_RS20150	COG1682	transport, permease protein
C7M53_RS20165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_RS20190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_RS20190	COG0463	Glycosyl transferase, family 2
C7M53_RS20195	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_RS20200	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7M53_RS20205	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C7M53_RS20210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
C7M53_RS20215	COG4193	domain, Protein
C7M53_RS20220	COG1482	cell wall glycoprotein biosynthetic process
C7M53_RS20240	COG0800	Aldolase
C7M53_RS20245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_RS20250	COG1609	Transcriptional regulator
C7M53_RS20255	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
C7M53_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS20265	COG1063	alcohol dehydrogenase
C7M53_RS20270	COG2814	Major facilitator Superfamily
C7M53_RS20275	COG1316	TRANSCRIPTIONal
C7M53_RS20280	COG0561	phosphatase activity
C7M53_RS20285	COG0791	NLP P60 protein
C7M53_RS20290	COG2843	Capsule synthesis protein
C7M53_RS20300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7M53_RS20305	COG1609	Transcriptional regulator
C7M53_RS20310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_RS20315	COG1869	D-ribose catabolic process
C7M53_RS20320	COG1129	ABC transporter
C7M53_RS20325	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7M53_RS20330	COG1879	ABC-type sugar transport system periplasmic component
C7M53_RS20340	COG3527	Alpha-acetolactate decarboxylase
C7M53_RS20345	COG0028	Belongs to the TPP enzyme family
C7M53_RS20350	COG0583	DNA-binding transcription factor activity
C7M53_RS20355	COG0405	Gamma-glutamyltransferase
C7M53_RS20360	COG1522	sequence-specific DNA binding
C7M53_RS20365	COG2059	Chromate
C7M53_RS20370	COG2059	Chromate
C7M53_RS20375	COG4464	protein tyrosine phosphatase activity
C7M53_RS20380	COG3944	biosynthesis protein
C7M53_RS20390	COG4715	Zinc finger, swim domain protein
C7M53_RS20395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7M53_RS20400	COG0561	phosphatase activity
C7M53_RS20405	COG1349	DNA-binding transcription factor activity
C7M53_RS20415	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS20425	COG3732	PTS system glucitol sorbitol-specific
C7M53_RS20445	COG0629	single-stranded DNA binding
C7M53_RS20460	COG1970	mechanosensitive ion channel activity
C7M53_RS20465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7M53_RS20470	COG4786	Flagellar basal body rod
C7M53_RS20475	COG4786	Flagellar basal body rod
C7M53_RS20480	COG1077	Cell shape determining protein MreB Mrl
C7M53_RS20485	COG1609	Transcriptional regulator
C7M53_RS20495	COG1846	Transcriptional regulator
C7M53_RS20500	COG2814	Major facilitator Superfamily
C7M53_RS20505	COG0671	phosphoesterase, PA-phosphatase related
C7M53_RS20510	COG1227	inorganic diphosphatase activity
C7M53_RS20515	COG3546	catalase activity
C7M53_RS20520	COG3361	conserved protein (COG2071)
C7M53_RS20525	COG0517	IMP dehydrogenase activity
C7M53_RS20530	COG0598	Magnesium transport protein CorA
C7M53_RS20535	COG1253	flavin adenine dinucleotide binding
C7M53_RS20540	COG0004	ammonium transporteR
C7M53_RS20545	COG0347	Belongs to the P(II) protein family
C7M53_RS20550	COG0740	serine-type endopeptidase activity
C7M53_RS20560	COG0739	heme binding
C7M53_RS20565	COG1247	-acetyltransferase
C7M53_RS20575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M53_RS20580	COG0477	Major facilitator Superfamily
C7M53_RS20585	COG3251	PFAM MbtH domain protein
C7M53_RS20590	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_RS20595	COG1535	isochorismatase
C7M53_RS20595	COG3433	isochorismatase activity
C7M53_RS20600	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7M53_RS20605	COG1169	isochorismate synthase
C7M53_RS20610	COG1028	Short-chain dehydrogenase reductase Sdr
C7M53_RS20615	COG2819	hydrolase of the alpha beta superfamily
C7M53_RS20620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS20625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7M53_RS20630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS20635	COG2207	Transcriptional regulator
C7M53_RS20635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS20645	COG2910	NAD(P)H-binding
C7M53_RS20650	COG1959	2 iron, 2 sulfur cluster binding
C7M53_RS20660	COG1994	Peptidase M50
C7M53_RS20665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7M53_RS20670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7M53_RS20675	COG2223	nitrite transmembrane transporter activity
C7M53_RS20680	COG3383	formate dehydrogenase (NAD+) activity
C7M53_RS20685	COG2304	oxidoreductase activity
C7M53_RS20690	COG2304	oxidoreductase activity
C7M53_RS20695	COG2385	sporulation resulting in formation of a cellular spore
C7M53_RS20700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M53_RS20710	COG4836	Membrane
C7M53_RS20715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7M53_RS20720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7M53_RS20725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7M53_RS20730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7M53_RS20735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M53_RS20740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7M53_RS20745	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7M53_RS20765	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7M53_RS20770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7M53_RS20775	COG4475	Protein of unknown function (DUF436)
C7M53_RS20780	COG0698	ribose 5-phosphate isomerase
C7M53_RS20785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7M53_RS20790	COG1971	Probably functions as a manganese efflux pump
C7M53_RS20795	COG0009	L-threonylcarbamoyladenylate synthase
C7M53_RS20800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7M53_RS20810	COG0738	Major facilitator superfamily
C7M53_RS20820	COG0561	phosphatase activity
C7M53_RS20825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7M53_RS20830	COG1609	Transcriptional regulator
C7M53_RS20835	COG2890	protein-(glutamine-N5) methyltransferase activity
C7M53_RS20840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7M53_RS20845	COG0346	lactoylglutathione lyase activity
C7M53_RS20850	COG0789	Transcriptional regulator
C7M53_RS20855	COG0679	Auxin Efflux Carrier
C7M53_RS20860	COG0281	malic enzyme
C7M53_RS20865	COG1435	thymidine kinase activity
C7M53_RS20870	COG0254	rRNA binding
C7M53_RS20875	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7M53_RS20880	COG1494	fructose-1,6-bisphosphatase
C7M53_RS20885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7M53_RS20890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7M53_RS20895	COG0191	fructose-bisphosphate aldolase activity
C7M53_RS20900	COG2204	response regulator
C7M53_RS20905	COG4821	SIS domain
C7M53_RS20910	COG0504	CTP synthase activity
C7M53_RS20915	COG3343	RNA polymerase activity
C7M53_RS20920	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS20925	COG1960	acyl-CoA dehydrogenase activity
C7M53_RS20930	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7M53_RS20935	COG0183	Belongs to the thiolase family
C7M53_RS20940	COG2181	nitrate reductase activity
C7M53_RS20940	COG0247	lactate metabolic process
C7M53_RS20945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7M53_RS20955	COG0018	arginyl-trna synthetase
C7M53_RS20960	COG4506	Protein conserved in bacteria
C7M53_RS20965	COG0010	Belongs to the arginase family
C7M53_RS20970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
C7M53_RS20985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7M53_RS20995	COG1994	Peptidase M50
C7M53_RS21000	COG1942	4-Oxalocrotonate Tautomerase
C7M53_RS21010	COG3465	dGTPase activity
C7M53_RS21015	COG1078	dGTPase activity
C7M53_RS21020	COG4844	belongs to the
C7M53_RS21045	COG2814	Major facilitator Superfamily
C7M53_RS21070	COG1414	Transcriptional regulator
C7M53_RS21080	COG0280	phosphate acetyltransferase
C7M53_RS21085	COG3253	May function as heme-dependent peroxidase
C7M53_RS21100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7M53_RS21120	COG1131	(ABC) transporter
C7M53_RS21135	COG2363	Small membrane protein
C7M53_RS21140	COG2233	PERMEase
C7M53_RS21150	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS21155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7M53_RS21160	COG1216	Glycosyl transferase, family 2
C7M53_RS21165	COG0351	phosphomethylpyrimidine kinase
C7M53_RS21175	COG1621	beta-fructofuranosidase activity
C7M53_RS21180	COG1263	PTS System
C7M53_RS21180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS21185	COG3711	transcriptional antiterminator
C7M53_RS21195	COG1404	Belongs to the peptidase S8 family
C7M53_RS21205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7M53_RS21210	COG0778	Nitroreductase
C7M53_RS21215	COG1473	amidohydrolase
C7M53_RS21220	COG0772	Belongs to the SEDS family
C7M53_RS21225	COG0772	Belongs to the SEDS family
C7M53_RS21230	COG3314	Sporulation integral membrane protein YlbJ
C7M53_RS21250	COG0456	acetyltransferase
C7M53_RS21285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7M53_RS21295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7M53_RS21300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7M53_RS21305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_RS21325	COG3162	membrane
C7M53_RS21330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS21335	COG1070	Carbohydrate kinase
C7M53_RS21340	COG2115	Belongs to the xylose isomerase family
C7M53_RS21350	COG0352	thiamine-phosphate diphosphorylase activity
C7M53_RS21355	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7M53_RS21360	COG0583	DNA-binding transcription factor activity
C7M53_RS21375	COG1380	Effector of murein hydrolase LrgA
C7M53_RS21380	COG1346	cytolysis
C7M53_RS21390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7M53_RS21395	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7M53_RS21400	COG0346	lactoylglutathione lyase activity
C7M53_RS21405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7M53_RS21410	COG1442	glycosyl transferase family 8
C7M53_RS21420	COG4585	Histidine kinase
C7M53_RS21425	COG2197	response regulator
C7M53_RS21435	COG5522	Integral membrane protein (intg_mem_TP0381)
C7M53_RS21440	COG2271	Major facilitator Superfamily
C7M53_RS21445	COG4948	Mandelate Racemase Muconate Lactonizing
C7M53_RS21450	COG0800	Aldolase
C7M53_RS21455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_RS21465	COG2234	aminopeptidase activity
C7M53_RS21470	COG0477	Major facilitator Superfamily
C7M53_RS21480	COG2357	RelA SpoT domain protein
C7M53_RS21495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7M53_RS21500	COG1696	Membrane protein involved in D-alanine export
C7M53_RS21505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7M53_RS21510	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7M53_RS21515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7M53_RS21520	COG2814	Major facilitator Superfamily
C7M53_RS21525	COG1486	melibiose metabolic process
C7M53_RS21530	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7M53_RS21535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS21540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS21545	COG3711	transcriptional antiterminator
C7M53_RS21545	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7M53_RS21550	COG2094	Belongs to the DNA glycosylase MPG family
C7M53_RS21560	COG0372	Belongs to the citrate synthase family
C7M53_RS21565	COG2079	MmgE PrpD family protein
C7M53_RS21570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7M53_RS21585	COG1132	(ABC) transporter
C7M53_RS21590	COG2755	lipolytic protein G-D-S-L family
C7M53_RS21605	COG2814	Major facilitator Superfamily
C7M53_RS21610	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_RS21615	COG1131	(ABC) transporter
C7M53_RS21635	COG1595	DNA-templated transcription, initiation
C7M53_RS21640	COG2814	Major facilitator Superfamily
C7M53_RS21645	COG0753	catalase activity
C7M53_RS21650	COG0753	catalase activity
C7M53_RS21655	COG0735	belongs to the Fur family
C7M53_RS21660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7M53_RS21665	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
C7M53_RS21670	COG1131	(ABC) transporter
C7M53_RS21685	COG1131	(ABC) transporter
C7M53_RS21740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7M53_RS21745	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7M53_RS21750	COG4988	ABC transporter
C7M53_RS21755	COG1294	oxidase, subunit
C7M53_RS21760	COG1271	oxidase subunit
C7M53_RS21770	COG2116	formate transmembrane transporter activity
C7M53_RS21780	COG0281	malic enzyme
C7M53_RS21785	COG1757	Na H antiporter
C7M53_RS21790	COG1027	Aspartate ammonia-lyase
C7M53_RS21795	COG0252	asparaginase activity
C7M53_RS21800	COG1396	sequence-specific DNA binding
C7M53_RS21805	COG2706	6-phosphogluconolactonase activity
C7M53_RS21810	COG0745	RESPONSE REGULATOR receiver
C7M53_RS21815	COG2205	protein histidine kinase activity
C7M53_RS21825	COG1136	(ABC) transporter
C7M53_RS21830	COG0577	efflux transmembrane transporter activity
C7M53_RS21835	COG5294	Protein conserved in bacteria
C7M53_RS21845	COG0726	polysaccharide deacetylase
C7M53_RS21850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7M53_RS21860	COG3493	citrate carrier protein
C7M53_RS21865	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_RS21880	COG1368	sulfuric ester hydrolase activity
C7M53_RS21890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7M53_RS21910	COG2235	arginine
C7M53_RS21915	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7M53_RS21925	COG0549	Belongs to the carbamate kinase family
C7M53_RS21935	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS21940	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7M53_RS21950	COG1595	DNA-templated transcription, initiation
C7M53_RS21960	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7M53_RS21970	COG1621	beta-fructofuranosidase activity
C7M53_RS21975	COG2223	nitrite transmembrane transporter activity
C7M53_RS21985	COG1609	Transcriptional regulator
C7M53_RS22000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7M53_RS22005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M53_RS22010	COG0463	Glycosyl transferase, family 2
C7M53_RS22015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_RS22045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_RS22050	COG0693	protein deglycase activity
C7M53_RS22050	COG0753	catalase activity
C7M53_RS22060	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS22065	COG2190	(PTS) system
C7M53_RS22065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS22065	COG1263	PTS System
C7M53_RS22070	COG3711	transcriptional antiterminator
C7M53_RS22075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7M53_RS22080	COG1122	ATPase activity
C7M53_RS22085	COG4721	ABC-type cobalt transport system, permease component
C7M53_RS22095	COG2224	Isocitrate lyase
C7M53_RS22100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7M53_RS22110	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7M53_RS22115	COG0577	efflux transmembrane transporter activity
C7M53_RS22120	COG1136	(ABC) transporter
C7M53_RS22125	COG2205	protein histidine kinase activity
C7M53_RS22130	COG0745	RESPONSE REGULATOR receiver
C7M53_RS22135	COG2723	6-phospho-beta-galactosidase activity
C7M53_RS22140	COG2190	(PTS) system
C7M53_RS22140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS22140	COG1263	PTS System
C7M53_RS22150	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
C7M53_RS22170	COG0513	Belongs to the DEAD box helicase family
C7M53_RS22200	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7M53_RS22205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7M53_RS22210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7M53_RS22215	COG2390	Transcriptional regulator
C7M53_RS22225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C7M53_RS22230	COG3706	GGDEF domain
C7M53_RS22235	COG5298	Protein conserved in bacteria
C7M53_RS22250	COG3977	Valine--pyruvate aminotransferase
C7M53_RS22265	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7M53_RS22275	COG0191	fructose-bisphosphate aldolase activity
C7M53_RS22280	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_RS22285	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_RS22290	COG0673	inositol 2-dehydrogenase activity
C7M53_RS22295	COG2814	Major facilitator Superfamily
C7M53_RS22300	COG1082	Xylose isomerase domain protein TIM barrel
C7M53_RS22305	COG3962	Belongs to the TPP enzyme family
C7M53_RS22310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7M53_RS22315	COG3718	enzyme involved in inositol metabolism
C7M53_RS22320	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS22325	COG1349	DNA-binding transcription factor activity
C7M53_RS22330	COG0667	Aldo Keto reductase
C7M53_RS22335	COG0584	glycerophosphoryl diester phosphodiesterase
C7M53_RS22340	COG2271	Major facilitator Superfamily
C7M53_RS22345	COG0326	Molecular chaperone. Has ATPase activity
C7M53_RS22350	COG0488	(ABC) transporter
C7M53_RS22355	COG0561	phosphatase activity
C7M53_RS22375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7M53_RS22405	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
C7M53_RS22410	COG0577	efflux transmembrane transporter activity
C7M53_RS22415	COG1136	(ABC) transporter
C7M53_RS22420	COG2205	protein histidine kinase activity
C7M53_RS22425	COG0745	RESPONSE REGULATOR receiver
C7M53_RS22435	COG5278	phosphoserine phosphatase activity
C7M53_RS22435	COG0840	transmembrane signaling receptor activity
C7M53_RS22440	COG1115	amino acid carrier protein
C7M53_RS22445	COG0686	Belongs to the AlaDH PNT family
C7M53_RS22450	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C7M53_RS22455	COG1874	Beta-galactosidase
C7M53_RS22460	COG3833	ABC-type maltose transport systems, permease component
C7M53_RS22465	COG1175	transmembrane transport
C7M53_RS22470	COG2182	Extracellular solute-binding protein
C7M53_RS22475	COG1609	Transcriptional regulator
C7M53_RS22485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7M53_RS22490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7M53_RS22495	COG1940	carbohydrate kinase activity
C7M53_RS22520	COG1454	alcohol dehydrogenase
C7M53_RS22520	COG1012	belongs to the aldehyde dehydrogenase family
C7M53_RS22525	COG0450	alkyl hydroperoxide reductase
C7M53_RS22530	COG3634	alkyl hydroperoxide reductase activity
C7M53_RS22555	COG1131	(ABC) transporter
C7M53_RS22560	COG0842	Transport permease protein
C7M53_RS22570	COG2197	response regulator
C7M53_RS22595	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7M53_RS22610	COG0456	acetyltransferase
C7M53_RS22625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7M53_RS22630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7M53_RS22635	COG4853	Protein conserved in bacteria
C7M53_RS22640	COG4863	YycH protein
C7M53_RS22645	COG5002	protein histidine kinase activity
C7M53_RS22650	COG0745	RESPONSE REGULATOR receiver
C7M53_RS22675	COG1051	belongs to the nudix hydrolase family
C7M53_RS22680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7M53_RS22690	COG0305	Participates in initiation and elongation during chromosome replication
C7M53_RS22705	COG3093	addiction module antidote protein HigA
C7M53_RS22710	COG2807	transmembrane transport
C7M53_RS22715	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7M53_RS22720	COG0363	glucosamine-6-phosphate deaminase activity
C7M53_RS22725	COG2188	Transcriptional regulator
C7M53_RS22730	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7M53_RS22735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7M53_RS22735	COG1263	PTS System
C7M53_RS22740	COG0359	binds to the 23S rRNA
C7M53_RS22745	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
C7M53_RS22750	COG4241	membrane
C7M53_RS22755	COG5577	PFAM Coat F domain
C7M53_RS22765	COG0659	secondary active sulfate transmembrane transporter activity
C7M53_RS22770	COG2271	Major facilitator Superfamily
C7M53_RS22775	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7M53_RS22780	COG0629	single-stranded DNA binding
C7M53_RS22785	COG0360	Binds together with S18 to 16S ribosomal RNA
C7M53_RS22790	COG0012	GTP binding
C7M53_RS22800	COG4481	Protein conserved in bacteria
C7M53_RS22805	COG3949	Membrane
C7M53_RS22815	COG1475	DNA binding
C7M53_RS22820	COG1192	Involved in chromosome partitioning
C7M53_RS22825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7M53_RS22835	COG1475	DNA binding
C7M53_RS22840	COG0357	Ribosomal RNA small subunit methyltransferase G
C7M53_RS22845	COG0445	tRNA wobble uridine modification
C7M53_RS22850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7M53_RS22855	COG1847	R3H domain protein
C7M53_RS22860	COG0706	membrane insertase activity
C7M53_RS22865	COG0594	ribonuclease P activity
C7M53_RS22915	COG5644	endopeptidase inhibitor activity
C7M53_RS22925	COG0741	lytic transglycosylase activity
C7M53_RS22925	COG1196	nuclear chromosome segregation
C7M53_RS22925	COG0739	heme binding
C7M53_RS22940	COG1988	membrane-bound metal-dependent
C7M53_RS22985	COG2336	PFAM SpoVT AbrB
C7M53_RS22990	COG2337	Toxic component of a toxin-antitoxin (TA) module
C7M53_RS22995	COG0457	Tetratricopeptide repeat
C7M53_RS23050	COG2003	Belongs to the UPF0758 family
C7M53_RS23070	COG3209	COG3209 Rhs family protein
C7M53_RS23090	COG0328	RNA-DNA hybrid ribonuclease activity
C7M53_RS23220	COG5280	Phage tail tape measure protein TP901
C7M53_RS23220	COG3953	SLT domain
C7M53_RS23255	COG4824	toxin secretion phage lysis holin
C7M53_RS23260	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7M53_RS23265	COG1192	Involved in chromosome partitioning