locus-tag	class	description
D9Y32_RS00025	COG4608	Belongs to the ABC transporter superfamily
D9Y32_RS00030	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS00040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9Y32_RS00045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9Y32_RS00060	COG1744	ABC transporter substrate-binding protein PnrA-like
D9Y32_RS00070	COG2267	carboxylic ester hydrolase activity
D9Y32_RS00085	COG1968	undecaprenyl-diphosphatase activity
D9Y32_RS00090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9Y32_RS00095	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9Y32_RS00100	COG0505	Belongs to the CarA family
D9Y32_RS00105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9Y32_RS00110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D9Y32_RS00115	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9Y32_RS00120	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9Y32_RS00130	COG2151	metal-sulfur cluster biosynthetic enzyme
D9Y32_RS00135	COG1073	alpha beta
D9Y32_RS00140	COG0561	phosphatase activity
D9Y32_RS00150	COG0516	GMP reductase activity
D9Y32_RS00160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS00165	COG1307	EDD domain protein, DegV family
D9Y32_RS00180	COG2996	Protein conserved in bacteria
D9Y32_RS00185	COG1666	GTP binding
D9Y32_RS00190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D9Y32_RS00190	COG0646	methionine synthase
D9Y32_RS00195	COG1410	methionine synthase
D9Y32_RS00195	COG0646	methionine synthase
D9Y32_RS00200	COG2378	regulation of single-species biofilm formation
D9Y32_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS00210	COG2153	protein acetylation
D9Y32_RS00235	COG0076	glutamate decarboxylase activity
D9Y32_RS00245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9Y32_RS00275	COG1609	Transcriptional regulator
D9Y32_RS00285	COG2207	Transcriptional regulator
D9Y32_RS00285	COG1917	Cupin 2, conserved barrel domain protein
D9Y32_RS00290	COG0534	Mate efflux family protein
D9Y32_RS00295	COG0347	Belongs to the P(II) protein family
D9Y32_RS00300	COG0004	ammonium transporteR
D9Y32_RS00305	COG0367	asparagine synthase
D9Y32_RS00325	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9Y32_RS00335	COG5337	Spore coat protein CotH
D9Y32_RS00380	COG0419	ATPase involved in DNA repair
D9Y32_RS00385	COG0420	3'-5' exonuclease activity
D9Y32_RS00390	COG1074	ATP-dependent DNA helicase activity
D9Y32_RS00395	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9Y32_RS00400	COG4149	molybdate abc transporter
D9Y32_RS00405	COG0725	ABC transporter, periplasmic molybdate-binding protein
D9Y32_RS00415	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS00420	COG5002	protein histidine kinase activity
D9Y32_RS00430	COG4533	DNA binding
D9Y32_RS00435	COG2814	Major facilitator Superfamily
D9Y32_RS00435	COG0477	Major facilitator Superfamily
D9Y32_RS00440	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS00445	COG3546	catalase activity
D9Y32_RS00460	COG3180	Ammonia monooxygenase
D9Y32_RS00465	COG1486	melibiose metabolic process
D9Y32_RS00470	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS00475	COG1175	transmembrane transport
D9Y32_RS00480	COG1653	transport
D9Y32_RS00485	COG1609	Transcriptional regulator
D9Y32_RS00505	COG0457	Tetratricopeptide repeat
D9Y32_RS00515	COG2814	Major facilitator Superfamily
D9Y32_RS00520	COG0549	Belongs to the carbamate kinase family
D9Y32_RS00530	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9Y32_RS00535	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9Y32_RS00540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9Y32_RS00545	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
D9Y32_RS00550	COG3257	ureidoglycine aminohydrolase activity
D9Y32_RS00555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9Y32_RS00570	COG1404	Belongs to the peptidase S8 family
D9Y32_RS00575	COG0681	Belongs to the peptidase S26 family
D9Y32_RS00580	COG0398	Pfam SNARE associated Golgi protein
D9Y32_RS00590	COG4903	ComK protein
D9Y32_RS00600	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS00605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9Y32_RS00605	COG0723	plastoquinol--plastocyanin reductase activity
D9Y32_RS00610	COG0840	transmembrane signaling receptor activity
D9Y32_RS00615	COG0406	alpha-ribazole phosphatase activity
D9Y32_RS00620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS00625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS00630	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D9Y32_RS00635	COG0697	spore germination
D9Y32_RS00645	COG0501	Belongs to the peptidase M48B family
D9Y32_RS00660	COG1396	sequence-specific DNA binding
D9Y32_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS00675	COG0095	Lipoate-protein ligase
D9Y32_RS00680	COG1234	tRNA 3'-trailer cleavage
D9Y32_RS00690	COG1301	dicarboxylic acid transport
D9Y32_RS00700	COG1363	Peptidase, m42
D9Y32_RS00705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9Y32_RS00715	COG1309	transcriptional regulator
D9Y32_RS00720	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9Y32_RS00725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9Y32_RS00730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9Y32_RS00740	COG2329	Antibiotic biosynthesis monooxygenase
D9Y32_RS00745	COG3069	C4-dicarboxylate transmembrane transporter activity
D9Y32_RS00750	COG1473	amidohydrolase
D9Y32_RS00760	COG4473	ABC transporter
D9Y32_RS00765	COG1131	(ABC) transporter
D9Y32_RS00770	COG0537	adenosine 5'-monophosphoramidase activity
D9Y32_RS00775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D9Y32_RS00790	COG4980	gas vesicle protein
D9Y32_RS00795	COG1846	Transcriptional regulator
D9Y32_RS00825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9Y32_RS00835	COG3481	metal-dependent phosphohydrolase, HD sub domain
D9Y32_RS00840	COG4717	serine-type aminopeptidase activity
D9Y32_RS00845	COG0420	3'-5' exonuclease activity
D9Y32_RS00850	COG1668	transmembrane transport
D9Y32_RS00855	COG4152	abc transporter atp-binding protein
D9Y32_RS00870	COG1024	Enoyl-CoA hydratase
D9Y32_RS00880	COG0490	domain, Protein
D9Y32_RS00885	COG0475	glutathione-regulated potassium exporter activity
D9Y32_RS00890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9Y32_RS00895	COG0561	phosphatase activity
D9Y32_RS00905	COG3679	Belongs to the UPF0342 family
D9Y32_RS00910	COG4399	Belongs to the UPF0754 family
D9Y32_RS00915	COG0189	ligase activity
D9Y32_RS00920	COG0189	ligase activity
D9Y32_RS00930	COG2508	Transcriptional regulator
D9Y32_RS00935	COG3842	ATPase activity
D9Y32_RS00950	COG0702	epimerase
D9Y32_RS00955	COG1132	(ABC) transporter
D9Y32_RS00965	COG0589	response to stress
D9Y32_RS01010	COG2017	converts alpha-aldose to the beta-anomer
D9Y32_RS01015	COG1757	Na H antiporter
D9Y32_RS01025	COG0726	polysaccharide deacetylase
D9Y32_RS01035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9Y32_RS01040	COG0668	transmembrane transport
D9Y32_RS01050	COG0584	glycerophosphoryl diester phosphodiesterase
D9Y32_RS01055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9Y32_RS01060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9Y32_RS01080	COG1253	flavin adenine dinucleotide binding
D9Y32_RS01085	COG0789	Transcriptional regulator
D9Y32_RS01090	COG1253	flavin adenine dinucleotide binding
D9Y32_RS01095	COG1309	transcriptional regulator
D9Y32_RS01105	COG3152	Membrane
D9Y32_RS01110	COG0204	Acyl-transferase
D9Y32_RS01120	COG0662	Cupin 2, conserved barrel domain protein
D9Y32_RS01125	COG1595	DNA-templated transcription, initiation
D9Y32_RS01150	COG2207	Transcriptional regulator
D9Y32_RS01150	COG3708	Transcriptional regulator
D9Y32_RS01160	COG0733	neurotransmitter:sodium symporter activity
D9Y32_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS01170	COG2133	pyrroloquinoline quinone binding
D9Y32_RS01175	COG0372	Belongs to the citrate synthase family
D9Y32_RS01180	COG0583	DNA-binding transcription factor activity
D9Y32_RS01185	COG1388	LysM domain
D9Y32_RS01185	COG0791	NLP P60 protein
D9Y32_RS01190	COG2719	SpoVR family
D9Y32_RS01195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D9Y32_RS01195	COG1017	nitric oxide dioxygenase activity
D9Y32_RS01200	COG1959	2 iron, 2 sulfur cluster binding
D9Y32_RS01215	COG0431	NADPH-dependent FMN reductase
D9Y32_RS01220	COG2197	response regulator
D9Y32_RS01225	COG4585	Histidine kinase
D9Y32_RS01225	COG2203	Gaf domain
D9Y32_RS01240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9Y32_RS01245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9Y32_RS01250	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D9Y32_RS01255	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D9Y32_RS01260	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9Y32_RS01265	COG0604	alcohol dehydrogenase
D9Y32_RS01270	COG0679	Auxin Efflux Carrier
D9Y32_RS01275	COG2116	formate transmembrane transporter activity
D9Y32_RS01285	COG0488	(ABC) transporter
D9Y32_RS01290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9Y32_RS01290	COG3153	acetyltransferase
D9Y32_RS01295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9Y32_RS01300	COG0517	IMP dehydrogenase activity
D9Y32_RS01310	COG0564	pseudouridine synthase activity
D9Y32_RS01315	COG3764	Sortase (surface protein transpeptidase)
D9Y32_RS01320	COG4085	toxin activity
D9Y32_RS01320	COG0737	Belongs to the 5'-nucleotidase family
D9Y32_RS01320	COG1525	nuclease
D9Y32_RS01325	COG5002	protein histidine kinase activity
D9Y32_RS01330	COG5577	PFAM Coat F domain
D9Y32_RS01360	COG1464	Belongs to the NlpA lipoprotein family
D9Y32_RS01365	COG2011	ABC-type metal ion transport system permease component
D9Y32_RS01370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9Y32_RS01375	COG1278	Cold shock
D9Y32_RS01385	COG1131	(ABC) transporter
D9Y32_RS01390	COG1131	(ABC) transporter
D9Y32_RS01395	COG1131	(ABC) transporter
D9Y32_RS01410	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS01415	COG2814	Major facilitator Superfamily
D9Y32_RS01420	COG1566	PFAM secretion protein HlyD family protein
D9Y32_RS01425	COG2718	Belongs to the UPF0229 family
D9Y32_RS01430	COG2766	serine protein kinase
D9Y32_RS01440	COG1664	Polymer-forming cytoskeletal
D9Y32_RS01445	COG0789	Transcriptional regulator
D9Y32_RS01450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9Y32_RS01460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9Y32_RS01465	COG3382	B3 4 domain protein
D9Y32_RS01475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9Y32_RS01495	COG1131	(ABC) transporter
D9Y32_RS01505	COG1476	TRANSCRIPTIONal
D9Y32_RS01515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9Y32_RS01520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9Y32_RS01525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9Y32_RS01530	COG1116	anion transmembrane transporter activity
D9Y32_RS01535	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9Y32_RS01540	COG0710	3-dehydroquinate dehydratase activity
D9Y32_RS01550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9Y32_RS01555	COG0457	Tetratricopeptide repeat
D9Y32_RS01620	COG0457	Tetratricopeptide repeat
D9Y32_RS01730	COG0735	belongs to the Fur family
D9Y32_RS01735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9Y32_RS01740	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9Y32_RS01745	COG4129	membrane
D9Y32_RS01750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9Y32_RS01755	COG0601	transmembrane transport
D9Y32_RS01760	COG0747	negative chemotaxis
D9Y32_RS01765	COG4608	Belongs to the ABC transporter superfamily
D9Y32_RS01770	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS01775	COG1132	(ABC) transporter
D9Y32_RS01780	COG3557	Belongs to the UPF0374 family
D9Y32_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS01805	COG1194	a g-specific adenine glycosylase
D9Y32_RS01810	COG1988	membrane-bound metal-dependent
D9Y32_RS01815	COG4485	Bacterial membrane protein, YfhO
D9Y32_RS01825	COG0463	Glycosyl transferase, family 2
D9Y32_RS01855	COG2137	regulation of response to DNA damage stimulus
D9Y32_RS01860	COG1090	epimerase
D9Y32_RS01880	COG0778	Nitroreductase
D9Y32_RS01885	COG0384	phenazine biosynthesis protein PhzF
D9Y32_RS01890	COG0392	lysyltransferase activity
D9Y32_RS01890	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9Y32_RS01905	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS01915	COG2207	Transcriptional regulator
D9Y32_RS01915	COG1917	Cupin 2, conserved barrel domain protein
D9Y32_RS01920	COG3507	Belongs to the glycosyl hydrolase 43 family
D9Y32_RS01930	COG2514	catechol 2,3-dioxygenase activity
D9Y32_RS01935	COG2259	Doxx family
D9Y32_RS01940	COG1733	regulation of RNA biosynthetic process
D9Y32_RS01955	COG1263	PTS System
D9Y32_RS01955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS01960	COG1737	Transcriptional regulator
D9Y32_RS01965	COG1486	melibiose metabolic process
D9Y32_RS01970	COG1742	UPF0060 membrane protein
D9Y32_RS01975	COG3284	Transcriptional regulator
D9Y32_RS01980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9Y32_RS01985	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9Y32_RS01990	COG0022	dehydrogenase e1 component
D9Y32_RS01995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9Y32_RS02005	COG5609	conserved protein (DUF2294)
D9Y32_RS02010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9Y32_RS02015	COG3002	Belongs to the UPF0753 family
D9Y32_RS02020	COG0288	reversible hydration of carbon dioxide
D9Y32_RS02025	COG3711	transcriptional antiterminator
D9Y32_RS02030	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS02030	COG1263	PTS System
D9Y32_RS02035	COG0477	Major facilitator Superfamily
D9Y32_RS02045	COG1819	glycosyl
D9Y32_RS02070	COG4637	Psort location Cytoplasmic, score
D9Y32_RS02075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9Y32_RS02080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9Y32_RS02085	COG0598	Magnesium transport protein CorA
D9Y32_RS02095	COG0371	Dehydrogenase
D9Y32_RS02100	COG0726	polysaccharide deacetylase
D9Y32_RS02110	COG0535	radical SAM domain protein
D9Y32_RS02120	COG0387	Pfam Sodium calcium exchanger
D9Y32_RS02130	COG0477	Major facilitator Superfamily
D9Y32_RS02135	COG1295	ribonuclease BN
D9Y32_RS02140	COG4980	gas vesicle protein
D9Y32_RS02145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9Y32_RS02150	COG1115	amino acid carrier protein
D9Y32_RS02155	COG4840	Belongs to the UPF0435 family
D9Y32_RS02160	COG0693	protein deglycase activity
D9Y32_RS02170	COG0778	Nitroreductase
D9Y32_RS02175	COG1733	regulation of RNA biosynthetic process
D9Y32_RS02180	COG0657	acetylesterase activity
D9Y32_RS02190	COG0673	inositol 2-dehydrogenase activity
D9Y32_RS02200	COG0463	Glycosyl transferase, family 2
D9Y32_RS02200	COG0457	Tetratricopeptide repeat
D9Y32_RS02205	COG1215	transferase activity, transferring glycosyl groups
D9Y32_RS02215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9Y32_RS02220	COG1045	serine acetyltransferase
D9Y32_RS02225	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9Y32_RS02250	COG2188	Transcriptional regulator
D9Y32_RS02255	COG0366	Alpha amylase catalytic
D9Y32_RS02260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS02260	COG1263	PTS System
D9Y32_RS02275	COG1368	sulfuric ester hydrolase activity
D9Y32_RS02280	COG0024	Methionine aminopeptidase
D9Y32_RS02290	COG2258	MOSC domain
D9Y32_RS02295	COG1254	Belongs to the acylphosphatase family
D9Y32_RS02300	COG0640	Transcriptional regulator
D9Y32_RS02305	COG5658	integral membrane protein
D9Y32_RS02310	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9Y32_RS02320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS02340	COG1136	(ABC) transporter
D9Y32_RS02350	COG0471	metal ion transport
D9Y32_RS02365	COG2130	NADP-dependent
D9Y32_RS02370	COG0513	Belongs to the DEAD box helicase family
D9Y32_RS02375	COG0488	(ABC) transporter
D9Y32_RS02380	COG2814	Major facilitator Superfamily
D9Y32_RS02385	COG0789	Transcriptional regulator
D9Y32_RS02395	COG2124	cytochrome p450
D9Y32_RS02400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9Y32_RS02405	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D9Y32_RS02410	COG0156	8-amino-7-oxononanoate synthase activity
D9Y32_RS02415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9Y32_RS02420	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
D9Y32_RS02425	COG0523	cobalamin synthesis protein
D9Y32_RS02440	COG1469	GTP cyclohydrolase I activity
D9Y32_RS02445	COG0488	(ABC) transporter
D9Y32_RS02455	COG0840	transmembrane signaling receptor activity
D9Y32_RS02460	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS02475	COG0217	transcriptional regulatory protein
D9Y32_RS02490	COG0457	Tetratricopeptide repeat
D9Y32_RS02540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9Y32_RS02545	COG1597	lipid kinase activity
D9Y32_RS02550	COG1957	nucleoside hydrolase
D9Y32_RS02555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9Y32_RS02565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9Y32_RS02570	COG1309	transcriptional regulator
D9Y32_RS02575	COG4124	Belongs to the glycosyl hydrolase 26 family
D9Y32_RS02590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9Y32_RS02595	COG0154	amidase activity
D9Y32_RS02600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9Y32_RS02605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS02610	COG1285	pathogenesis
D9Y32_RS02615	COG0363	glucosamine-6-phosphate deaminase activity
D9Y32_RS02620	COG3457	Alanine racemase
D9Y32_RS02625	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9Y32_RS02630	COG0626	cystathionine gamma-synthase activity
D9Y32_RS02635	COG1735	metal-dependent hydrolase with the TIM-barrel fold
D9Y32_RS02655	COG2188	Transcriptional regulator
D9Y32_RS02660	COG4851	CamS sex pheromone cAM373 precursor
D9Y32_RS02665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9Y32_RS02670	COG0210	DNA helicase
D9Y32_RS02675	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9Y32_RS02680	COG4496	protein, YerC YecD
D9Y32_RS02685	COG1470	cell adhesion involved in biofilm formation
D9Y32_RS02690	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9Y32_RS02720	COG0151	Belongs to the GarS family
D9Y32_RS02725	COG0138	bifunctional purine biosynthesis protein purh
D9Y32_RS02730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9Y32_RS02735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9Y32_RS02740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9Y32_RS02745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9Y32_RS02750	COG0047	phosphoribosylformylglycinamidine synthase activity
D9Y32_RS02755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9Y32_RS02760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D9Y32_RS02765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9Y32_RS02770	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9Y32_RS02775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9Y32_RS02785	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9Y32_RS02800	COG2252	PERMEase
D9Y32_RS02810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9Y32_RS02810	COG0519	Catalyzes the synthesis of GMP from XMP
D9Y32_RS02815	COG1305	Transglutaminase-like
D9Y32_RS02820	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9Y32_RS02825	COG0714	Associated with various cellular activities
D9Y32_RS02830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9Y32_RS02845	COG2132	Multicopper oxidase
D9Y32_RS02855	COG0702	epimerase
D9Y32_RS02885	COG0823	Involved in the tonB-independent uptake of proteins
D9Y32_RS02890	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D9Y32_RS02905	COG1846	Transcriptional regulator
D9Y32_RS02915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9Y32_RS02920	COG0366	Alpha amylase catalytic
D9Y32_RS02925	COG1554	hydrolase, family 65, central catalytic
D9Y32_RS02930	COG5521	maltodextrose utilization protein MalA
D9Y32_RS02935	COG3833	ABC-type maltose transport systems, permease component
D9Y32_RS02940	COG1175	transmembrane transport
D9Y32_RS02945	COG2182	Extracellular solute-binding protein
D9Y32_RS02950	COG0366	Alpha amylase catalytic
D9Y32_RS02955	COG1609	Transcriptional regulator
D9Y32_RS02965	COG0726	polysaccharide deacetylase
D9Y32_RS02990	COG0772	Belongs to the SEDS family
D9Y32_RS02995	COG0772	Belongs to the SEDS family
D9Y32_RS03000	COG3339	Conserved Protein
D9Y32_RS03005	COG1280	lysine exporter protein (LysE YggA)
D9Y32_RS03010	COG1378	Sugar-specific transcriptional regulator TrmB
D9Y32_RS03020	COG4260	virion core protein, lumpy skin disease virus
D9Y32_RS03025	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D9Y32_RS03030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9Y32_RS03035	COG1842	Phage shock protein A
D9Y32_RS03040	COG2814	Major facilitator Superfamily
D9Y32_RS03045	COG2272	Belongs to the type-B carboxylesterase lipase family
D9Y32_RS03050	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D9Y32_RS03055	COG3189	MarR family transcriptional regulator
D9Y32_RS03065	COG3848	Pyruvate phosphate dikinase
D9Y32_RS03065	COG0574	Belongs to the PEP-utilizing enzyme family
D9Y32_RS03070	COG1309	transcriptional regulator
D9Y32_RS03080	COG2135	peptidase activity
D9Y32_RS03095	COG2720	vancomycin resistance protein
D9Y32_RS03125	COG0459	protein refolding
D9Y32_RS03130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9Y32_RS03135	COG1266	CAAX protease self-immunity
D9Y32_RS03145	COG0805	protein transport
D9Y32_RS03150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9Y32_RS03155	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9Y32_RS03160	COG0315	cyclic pyranopterin monophosphate synthase activity
D9Y32_RS03165	COG0488	(ABC) transporter
D9Y32_RS03170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D9Y32_RS03175	COG0456	acetyltransferase
D9Y32_RS03180	COG1214	PFAM Peptidase M22, glycoprotease
D9Y32_RS03185	COG0802	atpase or kinase
D9Y32_RS03190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D9Y32_RS03230	COG2814	Major facilitator Superfamily
D9Y32_RS03240	COG3764	Sortase (surface protein transpeptidase)
D9Y32_RS03260	COG2814	Major facilitator Superfamily
D9Y32_RS03265	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS03265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D9Y32_RS03275	COG1595	DNA-templated transcription, initiation
D9Y32_RS03290	COG1113	amino acid transport
D9Y32_RS03295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D9Y32_RS03310	COG0583	DNA-binding transcription factor activity
D9Y32_RS03320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS03325	COG1733	regulation of RNA biosynthetic process
D9Y32_RS03335	COG2808	Putative FMN-binding domain
D9Y32_RS03340	COG0456	acetyltransferase
D9Y32_RS03345	COG1846	Transcriptional regulator
D9Y32_RS03350	COG2364	Membrane
D9Y32_RS03360	COG1063	alcohol dehydrogenase
D9Y32_RS03365	COG1278	Cold shock
D9Y32_RS03375	COG1476	TRANSCRIPTIONal
D9Y32_RS03420	COG3091	SprT-like family
D9Y32_RS03430	COG1033	growth of symbiont in host cell
D9Y32_RS03430	COG2409	Drug exporters of the RND superfamily
D9Y32_RS03435	COG1309	transcriptional regulator
D9Y32_RS03440	COG2183	response to ionizing radiation
D9Y32_RS03445	COG2208	phosphoserine phosphatase activity
D9Y32_RS03450	COG1191	sigma factor activity
D9Y32_RS03455	COG2172	sigma factor antagonist activity
D9Y32_RS03465	COG2208	phosphoserine phosphatase activity
D9Y32_RS03470	COG2172	sigma factor antagonist activity
D9Y32_RS03475	COG1366	Belongs to the anti-sigma-factor antagonist family
D9Y32_RS03480	COG1366	Belongs to the anti-sigma-factor antagonist family
D9Y32_RS03485	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9Y32_RS03490	COG0864	Transcriptional regulator
D9Y32_RS03495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9Y32_RS03500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9Y32_RS03505	COG0705	Rhomboid family
D9Y32_RS03510	COG3428	Bacterial PH domain
D9Y32_RS03515	COG3402	PFAM membrane-flanked domain
D9Y32_RS03520	COG0513	Belongs to the DEAD box helicase family
D9Y32_RS03530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9Y32_RS03535	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9Y32_RS03540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS03565	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9Y32_RS03570	COG1131	(ABC) transporter
D9Y32_RS03575	COG1301	dicarboxylic acid transport
D9Y32_RS03580	COG0628	permease
D9Y32_RS03590	COG0662	Cupin 2, conserved barrel domain protein
D9Y32_RS03600	COG2217	Heavy metal translocating P-type atpase
D9Y32_RS03605	COG4876	unkown
D9Y32_RS03610	COG1819	glycosyl
D9Y32_RS03615	COG1027	Aspartate ammonia-lyase
D9Y32_RS03620	COG2261	transglycosylase associated protein
D9Y32_RS03625	COG1914	H( )-stimulated, divalent metal cation uptake system
D9Y32_RS03630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9Y32_RS03640	COG3397	chitin binding
D9Y32_RS03645	COG0028	Belongs to the TPP enzyme family
D9Y32_RS03650	COG0531	amino acid
D9Y32_RS03655	COG0551	DNA topoisomerase type I activity
D9Y32_RS03655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9Y32_RS03660	COG1522	sequence-specific DNA binding
D9Y32_RS03670	COG2814	Major facilitator Superfamily
D9Y32_RS03685	COG3871	stress protein (general stress protein 26)
D9Y32_RS03695	COG1917	Cupin 2, conserved barrel domain protein
D9Y32_RS03700	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS03705	COG3711	transcriptional antiterminator
D9Y32_RS03710	COG0246	Mannitol dehydrogenase
D9Y32_RS03715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS03720	COG2213	PTS system mannitol-specific
D9Y32_RS03725	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS03730	COG1414	Transcriptional regulator
D9Y32_RS03735	COG1984	allophanate hydrolase subunit 2
D9Y32_RS03740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9Y32_RS03745	COG4336	lyase activity
D9Y32_RS03750	COG1914	H( )-stimulated, divalent metal cation uptake system
D9Y32_RS03755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9Y32_RS03760	COG0561	phosphatase activity
D9Y32_RS03765	COG3958	Transketolase
D9Y32_RS03770	COG3959	Transketolase, thiamine diphosphate binding domain
D9Y32_RS03785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS03800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9Y32_RS03805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9Y32_RS03810	COG0471	metal ion transport
D9Y32_RS03815	COG1802	Transcriptional regulator
D9Y32_RS03820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9Y32_RS03820	COG1587	Uroporphyrinogen-III synthase
D9Y32_RS03825	COG2146	nitrite reductase [NAD(P)H] activity
D9Y32_RS03830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9Y32_RS03835	COG0243	molybdopterin cofactor binding
D9Y32_RS03840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9Y32_RS03845	COG1349	DNA-binding transcription factor activity
D9Y32_RS03850	COG1276	copper resistance
D9Y32_RS03850	COG2372	response to copper ion
D9Y32_RS03855	COG4549	nuclear export factor GLE1
D9Y32_RS03865	COG0697	spore germination
D9Y32_RS03870	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS03875	COG0531	amino acid
D9Y32_RS03880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D9Y32_RS03885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9Y32_RS03890	COG0640	Transcriptional regulator
D9Y32_RS03895	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9Y32_RS03900	COG0778	Nitroreductase
D9Y32_RS03910	COG1309	transcriptional regulator
D9Y32_RS03915	COG2814	Major facilitator Superfamily
D9Y32_RS03920	COG4607	ABC-type enterochelin transport system periplasmic component
D9Y32_RS03925	COG4604	ABC transporter, ATP-binding protein
D9Y32_RS03930	COG4605	iron ion homeostasis
D9Y32_RS03935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS03940	COG0527	aspartate kinase activity
D9Y32_RS03950	COG3850	Histidine kinase
D9Y32_RS03950	COG5002	protein histidine kinase activity
D9Y32_RS03960	COG0577	efflux transmembrane transporter activity
D9Y32_RS03965	COG1136	(ABC) transporter
D9Y32_RS03970	COG0789	Transcriptional regulator
D9Y32_RS03975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D9Y32_RS03985	COG0697	spore germination
D9Y32_RS03995	COG5434	Belongs to the glycosyl hydrolase 28 family
D9Y32_RS04000	COG3104	oligopeptide transport
D9Y32_RS04005	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
D9Y32_RS04010	COG1874	Beta-galactosidase
D9Y32_RS04015	COG1846	Transcriptional regulator
D9Y32_RS04015	COG0456	acetyltransferase
D9Y32_RS04020	COG2271	Major facilitator Superfamily
D9Y32_RS04025	COG4214	carbohydrate transport
D9Y32_RS04035	COG4213	ABC transporter substrate-binding protein
D9Y32_RS04040	COG4753	response regulator
D9Y32_RS04040	COG2207	Transcriptional regulator
D9Y32_RS04045	COG2972	Histidine kinase
D9Y32_RS04065	COG5444	nuclease activity
D9Y32_RS04115	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D9Y32_RS04120	COG0163	prenyltransferase activity
D9Y32_RS04125	COG0583	DNA-binding transcription factor activity
D9Y32_RS04130	COG0010	Belongs to the arginase family
D9Y32_RS04135	COG0833	amino acid
D9Y32_RS04140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9Y32_RS04145	COG3829	transcription factor binding
D9Y32_RS04150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9Y32_RS04155	COG0765	amino acid transport
D9Y32_RS04160	COG1126	abc transporter atp-binding protein
D9Y32_RS04185	COG1131	(ABC) transporter
D9Y32_RS04195	COG2364	Membrane
D9Y32_RS04205	COG2819	hydrolase of the alpha beta superfamily
D9Y32_RS04215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D9Y32_RS04220	COG0697	spore germination
D9Y32_RS04225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D9Y32_RS04230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9Y32_RS04235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9Y32_RS04240	COG1177	transmembrane transport
D9Y32_RS04245	COG1176	ABC-type spermidine putrescine transport system, permease component I
D9Y32_RS04270	COG5444	nuclease activity
D9Y32_RS04280	COG3209	COG3209 Rhs family protein
D9Y32_RS04290	COG2723	6-phospho-beta-galactosidase activity
D9Y32_RS04300	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS04305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9Y32_RS04310	COG0765	amino acid transport
D9Y32_RS04330	COG3458	cephalosporin-C deacetylase activity
D9Y32_RS04340	COG3689	TIGRFAM TIGR03943 family protein
D9Y32_RS04345	COG2508	Transcriptional regulator
D9Y32_RS04350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS04355	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS04360	COG0506	proline dehydrogenase activity
D9Y32_RS04365	COG3541	Predicted nucleotidyltransferase
D9Y32_RS04370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9Y32_RS04375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D9Y32_RS04380	COG1113	amino acid transport
D9Y32_RS04385	COG1280	lysine exporter protein (LysE YggA)
D9Y32_RS04390	COG1620	l-lactate permease
D9Y32_RS04395	COG0039	L-malate dehydrogenase activity
D9Y32_RS04400	COG2223	nitrite transmembrane transporter activity
D9Y32_RS04405	COG0789	Transcriptional regulator
D9Y32_RS04415	COG0785	Cytochrome C biogenesis protein
D9Y32_RS04420	COG3853	Toxic anion resistance protein (TelA)
D9Y32_RS04440	COG0861	Integral membrane protein TerC family
D9Y32_RS04445	COG2310	stress, protein
D9Y32_RS04450	COG2310	stress, protein
D9Y32_RS04455	COG2310	stress, protein
D9Y32_RS04475	COG1309	transcriptional regulator
D9Y32_RS04480	COG1131	(ABC) transporter
D9Y32_RS04490	COG3883	PFAM NLP P60 protein
D9Y32_RS04490	COG0791	NLP P60 protein
D9Y32_RS04495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9Y32_RS04500	COG3773	Cell wall hydrolase
D9Y32_RS04510	COG1595	DNA-templated transcription, initiation
D9Y32_RS04520	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS04525	COG3591	Belongs to the peptidase S1B family
D9Y32_RS04540	COG3394	polysaccharide catabolic process
D9Y32_RS04545	COG2188	Transcriptional regulator
D9Y32_RS04550	COG1486	melibiose metabolic process
D9Y32_RS04555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS04560	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9Y32_RS04565	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS04570	COG0277	FAD linked oxidase domain protein
D9Y32_RS04575	COG0247	lactate metabolic process
D9Y32_RS04585	COG2261	transglycosylase associated protein
D9Y32_RS04600	COG0456	acetyltransferase
D9Y32_RS04610	COG1288	antiporter activity
D9Y32_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS04630	COG1942	4-Oxalocrotonate Tautomerase
D9Y32_RS04635	COG0583	DNA-binding transcription factor activity
D9Y32_RS04660	COG1131	(ABC) transporter
D9Y32_RS04665	COG1405	negative regulation of cell septum assembly
D9Y32_RS04665	COG3012	SEC-C Motif Domain Protein
D9Y32_RS04670	COG1714	RDD family
D9Y32_RS04675	COG0697	spore germination
D9Y32_RS04700	COG0789	Transcriptional regulator
D9Y32_RS04720	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS04725	COG1846	Transcriptional regulator
D9Y32_RS04730	COG3173	Aminoglycoside phosphotransferase
D9Y32_RS04755	COG1131	(ABC) transporter
D9Y32_RS04760	COG2205	protein histidine kinase activity
D9Y32_RS04770	COG2721	sulfolactate sulfo-lyase activity
D9Y32_RS04775	COG2186	Transcriptional regulator
D9Y32_RS04780	COG4948	Mandelate Racemase Muconate Lactonizing
D9Y32_RS04785	COG2271	Major facilitator Superfamily
D9Y32_RS04790	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS04795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9Y32_RS04800	COG0805	protein transport
D9Y32_RS04805	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9Y32_RS04810	COG3540	Alkaline phosphatase
D9Y32_RS04835	COG0784	Response regulator, receiver
D9Y32_RS04840	COG4191	Histidine kinase
D9Y32_RS04845	COG2066	Belongs to the glutaminase family
D9Y32_RS04850	COG1115	amino acid carrier protein
D9Y32_RS04855	COG2205	protein histidine kinase activity
D9Y32_RS04865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9Y32_RS04865	COG4451	ribulose bisphosphate carboxylase, small
D9Y32_RS04870	COG2323	membrane
D9Y32_RS04875	COG0789	Transcriptional regulator
D9Y32_RS04880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS04880	COG2190	(PTS) system
D9Y32_RS04880	COG1263	PTS System
D9Y32_RS04890	COG2040	homocysteine
D9Y32_RS04895	COG0833	amino acid
D9Y32_RS04920	COG4213	ABC transporter substrate-binding protein
D9Y32_RS04925	COG0840	transmembrane signaling receptor activity
D9Y32_RS04930	COG0371	Dehydrogenase
D9Y32_RS04950	COG2207	Transcriptional regulator
D9Y32_RS04950	COG1917	Cupin 2, conserved barrel domain protein
D9Y32_RS04955	COG0697	spore germination
D9Y32_RS04980	COG4682	membrane
D9Y32_RS04985	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9Y32_RS05005	COG0477	Major facilitator Superfamily
D9Y32_RS05015	COG1331	Highly conserved protein containing a thioredoxin domain
D9Y32_RS05035	COG2211	Major facilitator Superfamily
D9Y32_RS05050	COG3290	protein histidine kinase activity
D9Y32_RS05055	COG4565	transcriptional regulatory protein
D9Y32_RS05060	COG3181	Tripartite tricarboxylate transporter family receptor
D9Y32_RS05065	COG2851	Citrate transporter
D9Y32_RS05070	COG1113	amino acid transport
D9Y32_RS05075	COG1011	Hydrolase
D9Y32_RS05100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9Y32_RS05105	COG1132	(ABC) transporter
D9Y32_RS05115	COG2814	Major facilitator Superfamily
D9Y32_RS05120	COG0640	Transcriptional regulator
D9Y32_RS05125	COG1725	Transcriptional regulator
D9Y32_RS05145	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9Y32_RS05150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9Y32_RS05155	COG4856	YbbR-like protein
D9Y32_RS05160	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9Y32_RS05165	COG5662	AntiSigma factor
D9Y32_RS05170	COG1595	DNA-templated transcription, initiation
D9Y32_RS05205	COG1683	Conserved Protein
D9Y32_RS05210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9Y32_RS05215	COG1737	Transcriptional regulator
D9Y32_RS05220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS05220	COG1263	PTS System
D9Y32_RS05225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9Y32_RS05230	COG1472	Belongs to the glycosyl hydrolase 3 family
D9Y32_RS05235	COG3876	Protein conserved in bacteria
D9Y32_RS05250	COG0385	Bile acid
D9Y32_RS05260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9Y32_RS05290	COG1396	sequence-specific DNA binding
D9Y32_RS05380	COG4974	Belongs to the 'phage' integrase family
D9Y32_RS05405	COG0726	polysaccharide deacetylase
D9Y32_RS05410	COG2194	sulfuric ester hydrolase activity
D9Y32_RS05420	COG0489	protein tyrosine kinase activity
D9Y32_RS05425	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS05435	COG2318	DinB family
D9Y32_RS05450	COG4824	toxin secretion phage lysis holin
D9Y32_RS05600	COG0629	single-stranded DNA binding
D9Y32_RS05615	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
D9Y32_RS05645	COG1484	DNA-dependent DNA replication
D9Y32_RS05680	COG3617	BRO family, N-terminal domain
D9Y32_RS05700	COG3620	sequence-specific DNA binding
D9Y32_RS05720	COG2856	Zn peptidase
D9Y32_RS05725	COG0582	viral genome integration into host DNA
D9Y32_RS05730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9Y32_RS05735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9Y32_RS05740	COG0101	tRNA pseudouridine synthase activity
D9Y32_RS05745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9Y32_RS05750	COG1122	ATPase activity
D9Y32_RS05755	COG1122	ATPase activity
D9Y32_RS05760	COG0203	ribosomal protein L17
D9Y32_RS05765	COG0202	RNA polymerase activity
D9Y32_RS05770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9Y32_RS05780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9Y32_RS05785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9Y32_RS05790	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9Y32_RS05795	COG0024	Methionine aminopeptidase
D9Y32_RS05800	COG0563	adenylate kinase activity
D9Y32_RS05805	COG0201	protein transport
D9Y32_RS05810	COG0200	Binds to the 23S rRNA
D9Y32_RS05815	COG1841	ribosomal large subunit assembly
D9Y32_RS05820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9Y32_RS05825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9Y32_RS05830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9Y32_RS05835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D9Y32_RS05840	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9Y32_RS05845	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9Y32_RS05850	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D9Y32_RS05855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D9Y32_RS05860	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9Y32_RS05865	COG0255	Belongs to the universal ribosomal protein uL29 family
D9Y32_RS05870	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9Y32_RS05875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9Y32_RS05880	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9Y32_RS05885	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9Y32_RS05890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9Y32_RS05895	COG0089	rRNA binding
D9Y32_RS05900	COG0088	Forms part of the polypeptide exit tunnel
D9Y32_RS05905	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9Y32_RS05915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9Y32_RS05920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D9Y32_RS05925	COG0049	tRNA binding
D9Y32_RS05930	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9Y32_RS05935	COG1358	cellular component organization or biogenesis
D9Y32_RS05940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9Y32_RS05945	COG0085	RNA polymerase activity
D9Y32_RS05950	COG2813	Specifically methylates the guanine in position
D9Y32_RS05955	COG0222	ribosome binding
D9Y32_RS05960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D9Y32_RS05965	COG0081	regulation of translation
D9Y32_RS05970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9Y32_RS05975	COG0250	Participates in transcription elongation, termination and antitermination
D9Y32_RS05985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9Y32_RS05995	COG3688	RNA-binding protein containing a PIN domain
D9Y32_RS06000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9Y32_RS06005	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D9Y32_RS06010	COG0215	cysteine-tRNA ligase activity
D9Y32_RS06015	COG1045	serine acetyltransferase
D9Y32_RS06020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9Y32_RS06025	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9Y32_RS06030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9Y32_RS06035	COG4956	integral membrane protein (PIN domain superfamily)
D9Y32_RS06040	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9Y32_RS06045	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9Y32_RS06050	COG0542	response to heat
D9Y32_RS06055	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9Y32_RS06060	COG3880	PFAM UvrB UvrC protein
D9Y32_RS06065	COG4463	regulation of RNA biosynthetic process
D9Y32_RS06145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D9Y32_RS06150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9Y32_RS06155	COG1396	sequence-specific DNA binding
D9Y32_RS06160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9Y32_RS06165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9Y32_RS06170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9Y32_RS06175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9Y32_RS06180	COG0512	Glutamine amidotransferase of anthranilate synthase
D9Y32_RS06185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9Y32_RS06195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9Y32_RS06200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9Y32_RS06205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9Y32_RS06210	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9Y32_RS06215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9Y32_RS06220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9Y32_RS06225	COG0037	tRNA processing
D9Y32_RS06230	COG0515	serine threonine protein kinase
D9Y32_RS06235	COG2304	oxidoreductase activity
D9Y32_RS06240	COG2208	phosphoserine phosphatase activity
D9Y32_RS06255	COG1098	S1 RNA binding domain
D9Y32_RS06260	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9Y32_RS06275	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9Y32_RS06280	COG3956	TIGRFAM MazG family protein
D9Y32_RS06285	COG2244	polysaccharide biosynthetic process
D9Y32_RS06290	COG2002	toxin-antitoxin pair type II binding
D9Y32_RS06295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9Y32_RS06305	COG0193	aminoacyl-tRNA hydrolase activity
D9Y32_RS06310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9Y32_RS06315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D9Y32_RS06320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9Y32_RS06325	COG2088	sporulation resulting in formation of a cellular spore
D9Y32_RS06330	COG0251	oxidation-reduction process
D9Y32_RS06335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9Y32_RS06340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9Y32_RS06350	COG4466	Protein conserved in bacteria
D9Y32_RS06360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D9Y32_RS06365	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9Y32_RS06370	COG3584	3D domain protein
D9Y32_RS06370	COG3583	domain protein
D9Y32_RS06375	COG0084	hydrolase, TatD family'
D9Y32_RS06380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9Y32_RS06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9Y32_RS06390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9Y32_RS06395	COG2827	Endonuclease containing a URI domain
D9Y32_RS06400	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9Y32_RS06405	COG4467	Involved in initiation control of chromosome replication
D9Y32_RS06410	COG1774	PSP1 C-terminal conserved region
D9Y32_RS06415	COG0470	DNA polymerase III
D9Y32_RS06420	COG1728	Protein conserved in bacteria
D9Y32_RS06425	COG3870	Protein conserved in bacteria
D9Y32_RS06430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9Y32_RS06435	COG1982	Orn Lys Arg decarboxylase major
D9Y32_RS06440	COG3853	Toxic anion resistance protein (TelA)
D9Y32_RS06445	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
D9Y32_RS06490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9Y32_RS06495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9Y32_RS06500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9Y32_RS06510	COG0590	tRNA wobble adenosine to inosine editing
D9Y32_RS06515	COG1335	isochorismatase
D9Y32_RS06520	COG3858	chitin binding
D9Y32_RS06520	COG1388	LysM domain
D9Y32_RS06525	COG1428	Deoxynucleoside kinase
D9Y32_RS06530	COG1428	Deoxynucleoside kinase
D9Y32_RS06550	COG2610	gluconate transmembrane transporter activity
D9Y32_RS06555	COG1929	Belongs to the glycerate kinase type-1 family
D9Y32_RS06560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D9Y32_RS06565	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9Y32_RS06570	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
D9Y32_RS06575	COG1686	Belongs to the peptidase S11 family
D9Y32_RS06580	COG0516	GMP reductase activity
D9Y32_RS06580	COG0517	IMP dehydrogenase activity
D9Y32_RS06615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9Y32_RS06620	COG0187	DNA topoisomerase II activity
D9Y32_RS06630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9Y32_RS06635	COG2501	S4 domain
D9Y32_RS06640	COG0592	DNA-directed DNA polymerase activity
D9Y32_RS06645	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9Y32_RS06655	COG0594	ribonuclease P activity
D9Y32_RS06660	COG0706	membrane insertase activity
D9Y32_RS06665	COG1847	R3H domain protein
D9Y32_RS06670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9Y32_RS06675	COG0445	tRNA wobble uridine modification
D9Y32_RS06680	COG0357	Ribosomal RNA small subunit methyltransferase G
D9Y32_RS06685	COG1475	DNA binding
D9Y32_RS06695	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9Y32_RS06700	COG1192	Involved in chromosome partitioning
D9Y32_RS06705	COG1475	DNA binding
D9Y32_RS06715	COG3949	Membrane
D9Y32_RS06720	COG4481	Protein conserved in bacteria
D9Y32_RS06730	COG0012	GTP binding
D9Y32_RS06735	COG0360	Binds together with S18 to 16S ribosomal RNA
D9Y32_RS06740	COG0629	single-stranded DNA binding
D9Y32_RS06745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9Y32_RS06750	COG2271	Major facilitator Superfamily
D9Y32_RS06755	COG0659	secondary active sulfate transmembrane transporter activity
D9Y32_RS06760	COG0589	response to stress
D9Y32_RS06765	COG5577	PFAM Coat F domain
D9Y32_RS06770	COG4241	membrane
D9Y32_RS06775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9Y32_RS06785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS06785	COG1263	PTS System
D9Y32_RS06790	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D9Y32_RS06795	COG2188	Transcriptional regulator
D9Y32_RS06800	COG0363	glucosamine-6-phosphate deaminase activity
D9Y32_RS06805	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9Y32_RS06810	COG2807	transmembrane transport
D9Y32_RS06815	COG3093	addiction module antidote protein HigA
D9Y32_RS06830	COG0305	Participates in initiation and elongation during chromosome replication
D9Y32_RS06840	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D9Y32_RS06845	COG1051	belongs to the nudix hydrolase family
D9Y32_RS06870	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS06875	COG5002	protein histidine kinase activity
D9Y32_RS06880	COG4863	YycH protein
D9Y32_RS06885	COG4853	Protein conserved in bacteria
D9Y32_RS06895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9Y32_RS06910	COG0456	acetyltransferase
D9Y32_RS06925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9Y32_RS06950	COG2197	response regulator
D9Y32_RS06955	COG4585	Histidine kinase
D9Y32_RS06960	COG0842	Transport permease protein
D9Y32_RS06965	COG1131	(ABC) transporter
D9Y32_RS06990	COG3634	alkyl hydroperoxide reductase activity
D9Y32_RS06995	COG0450	alkyl hydroperoxide reductase
D9Y32_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS07000	COG1454	alcohol dehydrogenase
D9Y32_RS07025	COG1940	carbohydrate kinase activity
D9Y32_RS07030	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9Y32_RS07035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9Y32_RS07045	COG1609	Transcriptional regulator
D9Y32_RS07050	COG2182	Extracellular solute-binding protein
D9Y32_RS07055	COG1175	transmembrane transport
D9Y32_RS07060	COG3833	ABC-type maltose transport systems, permease component
D9Y32_RS07065	COG1874	Beta-galactosidase
D9Y32_RS07070	COG3867	Arabinogalactan endo-beta-1,4-galactanase
D9Y32_RS07075	COG0686	Belongs to the AlaDH PNT family
D9Y32_RS07080	COG1115	amino acid carrier protein
D9Y32_RS07095	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS07100	COG2205	protein histidine kinase activity
D9Y32_RS07105	COG1136	(ABC) transporter
D9Y32_RS07110	COG0577	efflux transmembrane transporter activity
D9Y32_RS07115	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
D9Y32_RS07145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS07165	COG0561	phosphatase activity
D9Y32_RS07170	COG0488	(ABC) transporter
D9Y32_RS07175	COG0326	Molecular chaperone. Has ATPase activity
D9Y32_RS07180	COG2271	Major facilitator Superfamily
D9Y32_RS07185	COG0584	glycerophosphoryl diester phosphodiesterase
D9Y32_RS07190	COG0667	Aldo Keto reductase
D9Y32_RS07195	COG1349	DNA-binding transcription factor activity
D9Y32_RS07205	COG3718	enzyme involved in inositol metabolism
D9Y32_RS07210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9Y32_RS07215	COG3962	Belongs to the TPP enzyme family
D9Y32_RS07220	COG1082	Xylose isomerase domain protein TIM barrel
D9Y32_RS07225	COG2814	Major facilitator Superfamily
D9Y32_RS07230	COG0673	inositol 2-dehydrogenase activity
D9Y32_RS07235	COG1082	Xylose isomerase domain protein TIM barrel
D9Y32_RS07240	COG1082	Xylose isomerase domain protein TIM barrel
D9Y32_RS07245	COG0191	fructose-bisphosphate aldolase activity
D9Y32_RS07255	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9Y32_RS07270	COG3977	Valine--pyruvate aminotransferase
D9Y32_RS07280	COG1215	transferase activity, transferring glycosyl groups
D9Y32_RS07295	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D9Y32_RS07305	COG2390	Transcriptional regulator
D9Y32_RS07310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9Y32_RS07315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9Y32_RS07320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D9Y32_RS07350	COG0513	Belongs to the DEAD box helicase family
D9Y32_RS07355	COG3507	Belongs to the glycosyl hydrolase 43 family
D9Y32_RS07370	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
D9Y32_RS07380	COG1263	PTS System
D9Y32_RS07380	COG2190	(PTS) system
D9Y32_RS07380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS07385	COG2723	6-phospho-beta-galactosidase activity
D9Y32_RS07390	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS07395	COG2205	protein histidine kinase activity
D9Y32_RS07400	COG1136	(ABC) transporter
D9Y32_RS07405	COG0577	efflux transmembrane transporter activity
D9Y32_RS07410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9Y32_RS07420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D9Y32_RS07425	COG2224	Isocitrate lyase
D9Y32_RS07435	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9Y32_RS07440	COG4721	ABC-type cobalt transport system, permease component
D9Y32_RS07445	COG1122	ATPase activity
D9Y32_RS07450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9Y32_RS07460	COG1263	PTS System
D9Y32_RS07460	COG2190	(PTS) system
D9Y32_RS07460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS07465	COG2723	6-phospho-beta-galactosidase activity
D9Y32_RS07480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9Y32_RS07505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9Y32_RS07510	COG0463	Glycosyl transferase, family 2
D9Y32_RS07515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D9Y32_RS07520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D9Y32_RS07545	COG1175	transmembrane transport
D9Y32_RS07550	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS07555	COG2223	nitrite transmembrane transporter activity
D9Y32_RS07560	COG1621	beta-fructofuranosidase activity
D9Y32_RS07570	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9Y32_RS07580	COG1595	DNA-templated transcription, initiation
D9Y32_RS07590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS07595	COG2723	6-phospho-beta-galactosidase activity
D9Y32_RS07605	COG0549	Belongs to the carbamate kinase family
D9Y32_RS07615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9Y32_RS07620	COG2235	arginine
D9Y32_RS07635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS07645	COG1368	sulfuric ester hydrolase activity
D9Y32_RS07660	COG0584	glycerophosphoryl diester phosphodiesterase
D9Y32_RS07665	COG3493	citrate carrier protein
D9Y32_RS07695	COG5294	Protein conserved in bacteria
D9Y32_RS07705	COG1136	(ABC) transporter
D9Y32_RS07715	COG2205	protein histidine kinase activity
D9Y32_RS07720	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS07725	COG2706	6-phosphogluconolactonase activity
D9Y32_RS07730	COG1396	sequence-specific DNA binding
D9Y32_RS07735	COG0252	asparaginase activity
D9Y32_RS07740	COG1027	Aspartate ammonia-lyase
D9Y32_RS07745	COG1757	Na H antiporter
D9Y32_RS07750	COG0281	malic enzyme
D9Y32_RS07760	COG2116	formate transmembrane transporter activity
D9Y32_RS07770	COG1271	oxidase subunit
D9Y32_RS07775	COG1294	oxidase, subunit
D9Y32_RS07780	COG4988	ABC transporter
D9Y32_RS07785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D9Y32_RS07790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D9Y32_RS07845	COG1131	(ABC) transporter
D9Y32_RS07860	COG1131	(ABC) transporter
D9Y32_RS07865	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9Y32_RS07870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9Y32_RS07875	COG0735	belongs to the Fur family
D9Y32_RS07880	COG0753	catalase activity
D9Y32_RS07885	COG0753	catalase activity
D9Y32_RS07890	COG2814	Major facilitator Superfamily
D9Y32_RS07895	COG1595	DNA-templated transcription, initiation
D9Y32_RS07915	COG1131	(ABC) transporter
D9Y32_RS07920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9Y32_RS07940	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS07945	COG1132	(ABC) transporter
D9Y32_RS07960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D9Y32_RS07965	COG2079	MmgE PrpD family protein
D9Y32_RS07970	COG0372	Belongs to the citrate synthase family
D9Y32_RS07980	COG2094	Belongs to the DNA glycosylase MPG family
D9Y32_RS07985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS07985	COG3711	transcriptional antiterminator
D9Y32_RS07990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS07995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS08000	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9Y32_RS08005	COG1486	melibiose metabolic process
D9Y32_RS08010	COG2814	Major facilitator Superfamily
D9Y32_RS08015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9Y32_RS08020	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D9Y32_RS08025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9Y32_RS08030	COG1696	Membrane protein involved in D-alanine export
D9Y32_RS08035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9Y32_RS08050	COG2357	RelA SpoT domain protein
D9Y32_RS08060	COG0477	Major facilitator Superfamily
D9Y32_RS08065	COG2234	aminopeptidase activity
D9Y32_RS08075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9Y32_RS08085	COG2197	response regulator
D9Y32_RS08100	COG1442	glycosyl transferase family 8
D9Y32_RS08105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9Y32_RS08110	COG0346	lactoylglutathione lyase activity
D9Y32_RS08115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9Y32_RS08120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS08130	COG1346	cytolysis
D9Y32_RS08135	COG1380	Effector of murein hydrolase LrgA
D9Y32_RS08150	COG0583	DNA-binding transcription factor activity
D9Y32_RS08155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9Y32_RS08160	COG0352	thiamine-phosphate diphosphorylase activity
D9Y32_RS08170	COG2115	Belongs to the xylose isomerase family
D9Y32_RS08175	COG1070	Carbohydrate kinase
D9Y32_RS08180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS08185	COG3162	membrane
D9Y32_RS08210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9Y32_RS08215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9Y32_RS08220	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9Y32_RS08230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9Y32_RS08265	COG0456	acetyltransferase
D9Y32_RS08285	COG3314	Sporulation integral membrane protein YlbJ
D9Y32_RS08290	COG0772	Belongs to the SEDS family
D9Y32_RS08295	COG0772	Belongs to the SEDS family
D9Y32_RS08300	COG1473	amidohydrolase
D9Y32_RS08305	COG0778	Nitroreductase
D9Y32_RS08310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9Y32_RS08330	COG3711	transcriptional antiterminator
D9Y32_RS08335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS08335	COG1263	PTS System
D9Y32_RS08340	COG1621	beta-fructofuranosidase activity
D9Y32_RS08350	COG0351	phosphomethylpyrimidine kinase
D9Y32_RS08355	COG1216	Glycosyl transferase, family 2
D9Y32_RS08360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9Y32_RS08365	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS08375	COG2233	PERMEase
D9Y32_RS08380	COG2363	Small membrane protein
D9Y32_RS08395	COG1131	(ABC) transporter
D9Y32_RS08415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9Y32_RS08430	COG3253	May function as heme-dependent peroxidase
D9Y32_RS08435	COG0280	phosphate acetyltransferase
D9Y32_RS08445	COG1414	Transcriptional regulator
D9Y32_RS08480	COG4844	belongs to the
D9Y32_RS08485	COG1078	dGTPase activity
D9Y32_RS08490	COG3465	dGTPase activity
D9Y32_RS08500	COG1942	4-Oxalocrotonate Tautomerase
D9Y32_RS08505	COG1994	Peptidase M50
D9Y32_RS08515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9Y32_RS08530	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9Y32_RS08535	COG0010	Belongs to the arginase family
D9Y32_RS08540	COG4506	Protein conserved in bacteria
D9Y32_RS08545	COG0018	arginyl-trna synthetase
D9Y32_RS08555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9Y32_RS08560	COG2181	nitrate reductase activity
D9Y32_RS08560	COG0247	lactate metabolic process
D9Y32_RS08565	COG0183	Belongs to the thiolase family
D9Y32_RS08570	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9Y32_RS08575	COG1960	acyl-CoA dehydrogenase activity
D9Y32_RS08580	COG1960	acyl-CoA dehydrogenase activity
D9Y32_RS08585	COG3343	RNA polymerase activity
D9Y32_RS08590	COG0504	CTP synthase activity
D9Y32_RS08595	COG4821	SIS domain
D9Y32_RS08600	COG2204	response regulator
D9Y32_RS08605	COG0191	fructose-bisphosphate aldolase activity
D9Y32_RS08610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9Y32_RS08615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9Y32_RS08620	COG1494	fructose-1,6-bisphosphatase
D9Y32_RS08625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9Y32_RS08630	COG0254	rRNA binding
D9Y32_RS08635	COG1435	thymidine kinase activity
D9Y32_RS08640	COG0281	malic enzyme
D9Y32_RS08645	COG0679	Auxin Efflux Carrier
D9Y32_RS08650	COG0789	Transcriptional regulator
D9Y32_RS08655	COG0346	lactoylglutathione lyase activity
D9Y32_RS08660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9Y32_RS08665	COG2890	protein-(glutamine-N5) methyltransferase activity
D9Y32_RS08670	COG1609	Transcriptional regulator
D9Y32_RS08680	COG0561	phosphatase activity
D9Y32_RS08685	COG0673	inositol 2-dehydrogenase activity
D9Y32_RS08690	COG0738	Major facilitator superfamily
D9Y32_RS08700	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D9Y32_RS08705	COG0009	L-threonylcarbamoyladenylate synthase
D9Y32_RS08710	COG1971	Probably functions as a manganese efflux pump
D9Y32_RS08715	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9Y32_RS08720	COG0698	ribose 5-phosphate isomerase
D9Y32_RS08725	COG4475	Protein of unknown function (DUF436)
D9Y32_RS08730	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9Y32_RS08735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9Y32_RS08755	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9Y32_RS08760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9Y32_RS08765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9Y32_RS08770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9Y32_RS08775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9Y32_RS08780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9Y32_RS08785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D9Y32_RS08790	COG4836	Membrane
D9Y32_RS08805	COG2385	sporulation resulting in formation of a cellular spore
D9Y32_RS08810	COG2304	oxidoreductase activity
D9Y32_RS08815	COG2304	oxidoreductase activity
D9Y32_RS08820	COG3383	formate dehydrogenase (NAD+) activity
D9Y32_RS08825	COG2223	nitrite transmembrane transporter activity
D9Y32_RS08830	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D9Y32_RS08835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D9Y32_RS08840	COG1994	Peptidase M50
D9Y32_RS08850	COG1959	2 iron, 2 sulfur cluster binding
D9Y32_RS08855	COG2910	NAD(P)H-binding
D9Y32_RS08865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS08865	COG2207	Transcriptional regulator
D9Y32_RS08870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS08875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS08880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS08885	COG2819	hydrolase of the alpha beta superfamily
D9Y32_RS08890	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS08895	COG1169	isochorismate synthase
D9Y32_RS08900	COG1021	2,3-dihydroxybenzoate-AMP ligase
D9Y32_RS08905	COG1535	isochorismatase
D9Y32_RS08905	COG3433	isochorismatase activity
D9Y32_RS08910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D9Y32_RS08915	COG3251	PFAM MbtH domain protein
D9Y32_RS08920	COG0477	Major facilitator Superfamily
D9Y32_RS08925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9Y32_RS08935	COG1247	-acetyltransferase
D9Y32_RS08940	COG0739	heme binding
D9Y32_RS08950	COG0740	serine-type endopeptidase activity
D9Y32_RS08955	COG0347	Belongs to the P(II) protein family
D9Y32_RS08960	COG0004	ammonium transporteR
D9Y32_RS08965	COG1253	flavin adenine dinucleotide binding
D9Y32_RS08970	COG0598	Magnesium transport protein CorA
D9Y32_RS08975	COG0517	IMP dehydrogenase activity
D9Y32_RS08980	COG3361	conserved protein (COG2071)
D9Y32_RS08990	COG1227	inorganic diphosphatase activity
D9Y32_RS08995	COG0671	phosphoesterase, PA-phosphatase related
D9Y32_RS09005	COG1846	Transcriptional regulator
D9Y32_RS09015	COG1609	Transcriptional regulator
D9Y32_RS09020	COG1077	Cell shape determining protein MreB Mrl
D9Y32_RS09025	COG4786	Flagellar basal body rod
D9Y32_RS09030	COG4786	Flagellar basal body rod
D9Y32_RS09035	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D9Y32_RS09040	COG1970	mechanosensitive ion channel activity
D9Y32_RS09055	COG0629	single-stranded DNA binding
D9Y32_RS09075	COG3732	PTS system glucitol sorbitol-specific
D9Y32_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS09095	COG1349	DNA-binding transcription factor activity
D9Y32_RS09100	COG0561	phosphatase activity
D9Y32_RS09105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9Y32_RS09110	COG4715	Zinc finger, swim domain protein
D9Y32_RS09125	COG4464	protein tyrosine phosphatase activity
D9Y32_RS09130	COG2059	Chromate
D9Y32_RS09135	COG2059	Chromate
D9Y32_RS09140	COG1522	sequence-specific DNA binding
D9Y32_RS09145	COG0405	Gamma-glutamyltransferase
D9Y32_RS09150	COG0583	DNA-binding transcription factor activity
D9Y32_RS09155	COG0028	Belongs to the TPP enzyme family
D9Y32_RS09160	COG3527	Alpha-acetolactate decarboxylase
D9Y32_RS09170	COG1879	ABC-type sugar transport system periplasmic component
D9Y32_RS09175	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9Y32_RS09180	COG1129	ABC transporter
D9Y32_RS09185	COG1869	D-ribose catabolic process
D9Y32_RS09190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9Y32_RS09195	COG1609	Transcriptional regulator
D9Y32_RS09200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9Y32_RS09210	COG2843	Capsule synthesis protein
D9Y32_RS09215	COG0791	NLP P60 protein
D9Y32_RS09220	COG0561	phosphatase activity
D9Y32_RS09225	COG1316	TRANSCRIPTIONal
D9Y32_RS09230	COG2814	Major facilitator Superfamily
D9Y32_RS09235	COG1063	alcohol dehydrogenase
D9Y32_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS09245	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
D9Y32_RS09250	COG1609	Transcriptional regulator
D9Y32_RS09255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9Y32_RS09260	COG0800	Aldolase
D9Y32_RS09280	COG1482	cell wall glycoprotein biosynthetic process
D9Y32_RS09285	COG4193	domain, Protein
D9Y32_RS09290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9Y32_RS09295	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
D9Y32_RS09300	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9Y32_RS09305	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9Y32_RS09310	COG0463	Glycosyl transferase, family 2
D9Y32_RS09310	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
D9Y32_RS09315	COG1682	transport, permease protein
D9Y32_RS09320	COG1134	teichoic acid transport
D9Y32_RS09325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9Y32_RS09330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9Y32_RS09335	COG1316	TRANSCRIPTIONal
D9Y32_RS09345	COG2247	cell wall binding repeat
D9Y32_RS09345	COG2385	sporulation resulting in formation of a cellular spore
D9Y32_RS09350	COG2247	cell wall binding repeat
D9Y32_RS09350	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS09360	COG2244	polysaccharide biosynthetic process
D9Y32_RS09365	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS09365	COG0297	glycogen (starch) synthase activity
D9Y32_RS09370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9Y32_RS09375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9Y32_RS09380	COG3307	-O-antigen
D9Y32_RS09385	COG3206	protein involved in exopolysaccharide biosynthesis
D9Y32_RS09390	COG1215	transferase activity, transferring glycosyl groups
D9Y32_RS09395	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS09400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9Y32_RS09410	COG1316	TRANSCRIPTIONal
D9Y32_RS09415	COG1739	Uncharacterized protein family UPF0029
D9Y32_RS09420	COG4585	Histidine kinase
D9Y32_RS09425	COG2197	response regulator
D9Y32_RS09430	COG1307	EDD domain protein, DegV family
D9Y32_RS09435	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9Y32_RS09445	COG1040	competence protein
D9Y32_RS09455	COG2747	anti-sigma28 factor FlgM
D9Y32_RS09460	COG3418	PFAM FlgN family protein
D9Y32_RS09465	COG4786	Flagellar basal body rod
D9Y32_RS09465	COG1256	bacterial-type flagellum assembly
D9Y32_RS09470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9Y32_RS09480	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9Y32_RS09485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9Y32_RS09490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9Y32_RS09495	COG1334	flagellar protein FlaG
D9Y32_RS09500	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9Y32_RS09505	COG1516	flagellar protein fliS
D9Y32_RS09520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D9Y32_RS09525	COG0653	protein targeting
D9Y32_RS09535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS09540	COG2010	Cytochrome c
D9Y32_RS09550	COG2884	Cell division ATP-binding protein ftsE
D9Y32_RS09555	COG2177	Part of the ABC transporter FtsEX involved in
D9Y32_RS09560	COG3883	PFAM NLP P60 protein
D9Y32_RS09560	COG0791	NLP P60 protein
D9Y32_RS09565	COG0473	3-isopropylmalate dehydrogenase activity
D9Y32_RS09570	COG3409	Peptidoglycan-binding domain 1 protein
D9Y32_RS09570	COG0793	Belongs to the peptidase S41A family
D9Y32_RS09580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9Y32_RS09590	COG4897	Protein conserved in bacteria
D9Y32_RS09595	COG0556	nucleotide-excision repair
D9Y32_RS09600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9Y32_RS09625	COG3595	metallopeptidase activity
D9Y32_RS09630	COG1983	PspC domain protein
D9Y32_RS09635	COG1950	PFAM Membrane protein of
D9Y32_RS09640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9Y32_RS09645	COG2814	Major facilitator Superfamily
D9Y32_RS09650	COG1846	Transcriptional regulator
D9Y32_RS09655	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9Y32_RS09660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9Y32_RS09665	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9Y32_RS09670	COG0546	phosphoglycolate phosphatase activity
D9Y32_RS09675	COG0110	maltose O-acetyltransferase activity
D9Y32_RS09680	COG5297	Belongs to the glycosyl hydrolase family 6
D9Y32_RS09685	COG4990	cell redox homeostasis
D9Y32_RS09690	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9Y32_RS09695	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9Y32_RS09700	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9Y32_RS09705	COG0131	Imidazoleglycerol-phosphate dehydratase
D9Y32_RS09710	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9Y32_RS09715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9Y32_RS09720	COG0107	imidazoleglycerol-phosphate synthase activity
D9Y32_RS09725	COG0140	phosphoribosyl-ATP diphosphatase activity
D9Y32_RS09725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9Y32_RS09735	COG0457	Tetratricopeptide repeat
D9Y32_RS09740	COG0492	ferredoxin-NADP+ reductase activity
D9Y32_RS09750	COG1051	belongs to the nudix hydrolase family
D9Y32_RS09755	COG1660	Displays ATPase and GTPase activities
D9Y32_RS09760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9Y32_RS09765	COG1481	regulation of sporulation
D9Y32_RS09770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS09775	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D9Y32_RS09780	COG2732	(Barnase) inhibitor
D9Y32_RS09790	COG0640	Transcriptional regulator
D9Y32_RS09795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9Y32_RS09800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9Y32_RS09805	COG0288	reversible hydration of carbon dioxide
D9Y32_RS09810	COG0659	secondary active sulfate transmembrane transporter activity
D9Y32_RS09815	COG1078	dGTPase activity
D9Y32_RS09820	COG1694	Mazg nucleotide pyrophosphohydrolase
D9Y32_RS09825	COG1611	Belongs to the LOG family
D9Y32_RS09830	COG0740	serine-type endopeptidase activity
D9Y32_RS09845	COG4974	Belongs to the 'phage' integrase family
D9Y32_RS09860	COG0582	viral genome integration into host DNA
D9Y32_RS09975	COG1621	beta-fructofuranosidase activity
D9Y32_RS09980	COG1621	beta-fructofuranosidase activity
D9Y32_RS09985	COG1902	pentaerythritol trinitrate reductase activity
D9Y32_RS09990	COG1733	regulation of RNA biosynthetic process
D9Y32_RS10000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9Y32_RS10015	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D9Y32_RS10025	COG2271	Major facilitator Superfamily
D9Y32_RS10030	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS10035	COG1396	sequence-specific DNA binding
D9Y32_RS10040	COG3944	biosynthesis protein
D9Y32_RS10045	COG0489	protein tyrosine kinase activity
D9Y32_RS10050	COG1086	Polysaccharide biosynthesis protein
D9Y32_RS10055	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS10060	COG1215	transferase activity, transferring glycosyl groups
D9Y32_RS10065	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS10075	COG1216	Glycosyl transferase, family 2
D9Y32_RS10080	COG5039	Polysaccharide pyruvyl transferase
D9Y32_RS10085	COG1216	Glycosyl transferase, family 2
D9Y32_RS10090	COG2244	polysaccharide biosynthetic process
D9Y32_RS10095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9Y32_RS10100	COG0110	maltose O-acetyltransferase activity
D9Y32_RS10105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9Y32_RS10110	COG5039	Polysaccharide pyruvyl transferase
D9Y32_RS10120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9Y32_RS10125	COG1620	l-lactate permease
D9Y32_RS10130	COG2186	Transcriptional regulator
D9Y32_RS10135	COG0247	lactate metabolic process
D9Y32_RS10140	COG1139	Iron-sulfur cluster binding protein
D9Y32_RS10145	COG1556	Lactate utilization protein
D9Y32_RS10165	COG1113	amino acid transport
D9Y32_RS10170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9Y32_RS10175	COG2390	Transcriptional regulator
D9Y32_RS10180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9Y32_RS10190	COG0126	phosphoglycerate kinase activity
D9Y32_RS10195	COG0149	triose-phosphate isomerase activity
D9Y32_RS10200	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9Y32_RS10205	COG0148	phosphopyruvate hydratase activity
D9Y32_RS10210	COG0693	protein deglycase activity
D9Y32_RS10225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS10235	COG3064	Membrane
D9Y32_RS10240	COG2095	MarC family integral membrane protein
D9Y32_RS10245	COG1510	regulation of RNA biosynthetic process
D9Y32_RS10250	COG1125	glycine betaine transport
D9Y32_RS10250	COG0517	IMP dehydrogenase activity
D9Y32_RS10255	COG1174	glycine betaine transport
D9Y32_RS10260	COG1732	Glycine betaine
D9Y32_RS10265	COG1174	glycine betaine transport
D9Y32_RS10270	COG1396	sequence-specific DNA binding
D9Y32_RS10275	COG1396	sequence-specific DNA binding
D9Y32_RS10280	COG1476	TRANSCRIPTIONal
D9Y32_RS10285	COG2002	toxin-antitoxin pair type II binding
D9Y32_RS10290	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9Y32_RS10295	COG1647	Serine aminopeptidase, S33
D9Y32_RS10300	COG0557	exoribonuclease II activity
D9Y32_RS10305	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D9Y32_RS10375	COG2140	Oxalate decarboxylase
D9Y32_RS10385	COG1191	sigma factor activity
D9Y32_RS10395	COG1054	Belongs to the UPF0176 family
D9Y32_RS10400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9Y32_RS10405	COG0673	inositol 2-dehydrogenase activity
D9Y32_RS10415	COG1846	Transcriptional regulator
D9Y32_RS10425	COG2124	cytochrome p450
D9Y32_RS10435	COG2814	Major facilitator Superfamily
D9Y32_RS10440	COG2814	Major facilitator Superfamily
D9Y32_RS10445	COG3347	Dehydrogenase
D9Y32_RS10445	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS10455	COG4952	isomerase
D9Y32_RS10460	COG1070	Carbohydrate kinase
D9Y32_RS10465	COG1349	DNA-binding transcription factor activity
D9Y32_RS10470	COG0693	protein deglycase activity
D9Y32_RS10475	COG1937	Protein conserved in bacteria
D9Y32_RS10480	COG2608	mercury ion transmembrane transporter activity
D9Y32_RS10485	COG2217	Heavy metal translocating P-type atpase
D9Y32_RS10500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS10500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS10500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS10505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D9Y32_RS10505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D9Y32_RS10520	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9Y32_RS10525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9Y32_RS10530	COG1121	(ABC) transporter
D9Y32_RS10540	COG1501	Belongs to the glycosyl hydrolase 31 family
D9Y32_RS10545	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS10550	COG1175	transmembrane transport
D9Y32_RS10555	COG1653	transport
D9Y32_RS10560	COG2217	Heavy metal translocating P-type atpase
D9Y32_RS10565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9Y32_RS10570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9Y32_RS10575	COG0456	acetyltransferase
D9Y32_RS10580	COG0456	acetyltransferase
D9Y32_RS10580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9Y32_RS10585	COG2860	membrane
D9Y32_RS10590	COG3973	AAA domain
D9Y32_RS10600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9Y32_RS10605	COG1940	carbohydrate kinase activity
D9Y32_RS10610	COG0656	L-ascorbic acid biosynthetic process
D9Y32_RS10615	COG2814	Major facilitator Superfamily
D9Y32_RS10620	COG1368	sulfuric ester hydrolase activity
D9Y32_RS10625	COG1988	membrane-bound metal-dependent
D9Y32_RS10635	COG0531	amino acid
D9Y32_RS10640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS10645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS10650	COG1120	ATPase activity
D9Y32_RS10655	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS10660	COG2205	protein histidine kinase activity
D9Y32_RS10665	COG1904	glucuronate isomerase
D9Y32_RS10670	COG2211	Major facilitator Superfamily
D9Y32_RS10675	COG1609	Transcriptional regulator
D9Y32_RS10680	COG0246	Mannitol dehydrogenase
D9Y32_RS10685	COG2721	sulfolactate sulfo-lyase activity
D9Y32_RS10700	COG2258	MOSC domain
D9Y32_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS10710	COG1802	Transcriptional regulator
D9Y32_RS10715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS10720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS10725	COG1120	ATPase activity
D9Y32_RS10730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D9Y32_RS10735	COG1454	alcohol dehydrogenase
D9Y32_RS10750	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS10755	COG2096	Adenosyltransferase
D9Y32_RS10760	COG4677	pectinesterase activity
D9Y32_RS10765	COG4758	membrane
D9Y32_RS10770	COG1842	Phage shock protein A
D9Y32_RS10780	COG4758	membrane
D9Y32_RS10785	COG4585	Histidine kinase
D9Y32_RS10790	COG2197	response regulator
D9Y32_RS10805	COG0814	amino acid
D9Y32_RS10810	COG0697	spore germination
D9Y32_RS10820	COG0114	fumarate hydratase activity
D9Y32_RS10825	COG1309	transcriptional regulator
D9Y32_RS10830	COG2205	protein histidine kinase activity
D9Y32_RS10830	COG2770	Histidine kinase
D9Y32_RS10835	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS10840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9Y32_RS10845	COG0783	Belongs to the Dps family
D9Y32_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS10855	COG1686	Belongs to the peptidase S11 family
D9Y32_RS10870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS10875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS10880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9Y32_RS10885	COG1120	ATPase activity
D9Y32_RS10900	COG5577	PFAM Coat F domain
D9Y32_RS10915	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9Y32_RS10915	COG1024	Enoyl-CoA hydratase
D9Y32_RS10920	COG0183	Belongs to the thiolase family
D9Y32_RS10925	COG1960	acyl-CoA dehydrogenase activity
D9Y32_RS10930	COG1393	Belongs to the ArsC family
D9Y32_RS10935	COG0509	glycine decarboxylation via glycine cleavage system
D9Y32_RS10945	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9Y32_RS10950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS10960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9Y32_RS10965	COG2011	ABC-type metal ion transport system permease component
D9Y32_RS10970	COG1464	Belongs to the NlpA lipoprotein family
D9Y32_RS10975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9Y32_RS10985	COG0396	ATPase activity
D9Y32_RS10990	COG0719	Fe-S assembly protein
D9Y32_RS10995	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9Y32_RS11000	COG0822	iron-sulfur transferase activity
D9Y32_RS11005	COG0719	Fe-S assembly protein
D9Y32_RS11010	COG0457	Tetratricopeptide repeat
D9Y32_RS11025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9Y32_RS11035	COG2356	endonuclease I
D9Y32_RS11040	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9Y32_RS11045	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9Y32_RS11055	COG2814	Major facilitator Superfamily
D9Y32_RS11060	COG2508	Transcriptional regulator
D9Y32_RS11065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9Y32_RS11070	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D9Y32_RS11080	COG3226	Transcriptional regulator
D9Y32_RS11090	COG1801	Protein of unknown function DUF72
D9Y32_RS11095	COG0730	response to heat
D9Y32_RS11100	COG0737	Belongs to the 5'-nucleotidase family
D9Y32_RS11105	COG3377	Domain of unknown function (DUF1805)
D9Y32_RS11115	COG0733	neurotransmitter:sodium symporter activity
D9Y32_RS11125	COG0739	heme binding
D9Y32_RS11140	COG4470	Protein conserved in bacteria
D9Y32_RS11145	COG2445	Protein of unknown function DUF86
D9Y32_RS11150	COG0647	UMP catabolic process
D9Y32_RS11155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9Y32_RS11160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9Y32_RS11170	COG0460	homoserine dehydrogenase
D9Y32_RS11175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9Y32_RS11180	COG0083	homoserine kinase activity
D9Y32_RS11185	COG0823	Involved in the tonB-independent uptake of proteins
D9Y32_RS11185	COG4946	Tricorn protease homolog
D9Y32_RS11185	COG1506	peptidase
D9Y32_RS11190	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9Y32_RS11195	COG4837	Protein of unknown function (DUF1462)
D9Y32_RS11205	COG3479	Phenolic acid decarboxylase
D9Y32_RS11210	COG0457	Tetratricopeptide repeat
D9Y32_RS11220	COG5646	InterPro IPR014922
D9Y32_RS11225	COG1252	NADH dehydrogenase
D9Y32_RS11230	COG4844	belongs to the
D9Y32_RS11235	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9Y32_RS11240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9Y32_RS11245	COG0316	Belongs to the HesB IscA family
D9Y32_RS11250	COG0456	acetyltransferase
D9Y32_RS11265	COG0492	ferredoxin-NADP+ reductase activity
D9Y32_RS11270	COG1252	NADH dehydrogenase
D9Y32_RS11280	COG3584	3D domain protein
D9Y32_RS11285	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9Y32_RS11290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9Y32_RS11295	COG2056	Na+-H+ antiporter family
D9Y32_RS11300	COG1268	BioY protein
D9Y32_RS11305	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9Y32_RS11315	COG0686	Belongs to the AlaDH PNT family
D9Y32_RS11320	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9Y32_RS11320	COG2508	Transcriptional regulator
D9Y32_RS11325	COG1115	amino acid carrier protein
D9Y32_RS11330	COG4842	Belongs to the WXG100 family
D9Y32_RS11335	COG5417	Belongs to the EsaB family
D9Y32_RS11340	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9Y32_RS11345	COG1674	ftsk spoiiie
D9Y32_RS11345	COG0433	COG0433 Predicted ATPase
D9Y32_RS11350	COG1511	domain protein
D9Y32_RS11360	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS11365	COG1418	mRNA catabolic process
D9Y32_RS11375	COG0657	acetylesterase activity
D9Y32_RS11380	COG1959	2 iron, 2 sulfur cluster binding
D9Y32_RS11385	COG0628	permease
D9Y32_RS11400	COG5506	Protein of unknown function (DUF1694)
D9Y32_RS11405	COG1335	isochorismatase
D9Y32_RS11410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9Y32_RS11445	COG4585	Histidine kinase
D9Y32_RS11450	COG2197	response regulator
D9Y32_RS11455	COG2050	protein possibly involved in aromatic compounds catabolism
D9Y32_RS11460	COG1320	monovalent cation:proton antiporter activity
D9Y32_RS11465	COG2212	antiporter activity
D9Y32_RS11470	COG1863	multisubunit Na H antiporter MnhE subunit
D9Y32_RS11475	COG0651	ATP synthesis coupled electron transport
D9Y32_RS11480	COG1006	Multisubunit Na H antiporter MnhC subunit
D9Y32_RS11485	COG2111	Na H antiporter
D9Y32_RS11490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9Y32_RS11490	COG2111	Na H antiporter
D9Y32_RS11500	COG3493	citrate carrier protein
D9Y32_RS11505	COG0688	phosphatidylethanolamine metabolic process
D9Y32_RS11510	COG0586	Pfam SNARE associated Golgi protein
D9Y32_RS11515	COG1183	phosphatidylcholine synthase activity
D9Y32_RS11525	COG4565	transcriptional regulatory protein
D9Y32_RS11530	COG3290	protein histidine kinase activity
D9Y32_RS11540	COG3011	Protein conserved in bacteria
D9Y32_RS11550	COG2814	Major facilitator Superfamily
D9Y32_RS11555	COG5018	Exonuclease
D9Y32_RS11570	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9Y32_RS11585	COG2267	carboxylic ester hydrolase activity
D9Y32_RS11590	COG1522	sequence-specific DNA binding
D9Y32_RS11595	COG0436	Aminotransferase
D9Y32_RS11600	COG1098	S1 RNA binding domain
D9Y32_RS11605	COG2155	Conserved Protein
D9Y32_RS11610	COG1979	alcohol dehydrogenase
D9Y32_RS11615	COG0166	Belongs to the GPI family
D9Y32_RS11625	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
D9Y32_RS11630	COG2323	membrane
D9Y32_RS11640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9Y32_RS11655	COG2738	Putative neutral zinc metallopeptidase
D9Y32_RS11660	COG1253	flavin adenine dinucleotide binding
D9Y32_RS11665	COG5297	Belongs to the glycosyl hydrolase family 6
D9Y32_RS11680	COG0366	Alpha amylase catalytic
D9Y32_RS11685	COG0432	Pfam Uncharacterised protein family UPF0047
D9Y32_RS11690	COG2070	2-Nitropropane dioxygenase
D9Y32_RS11700	COG0840	transmembrane signaling receptor activity
D9Y32_RS11705	COG0840	transmembrane signaling receptor activity
D9Y32_RS11710	COG0840	transmembrane signaling receptor activity
D9Y32_RS11715	COG0693	protein deglycase activity
D9Y32_RS11725	COG0628	permease
D9Y32_RS11730	COG1968	undecaprenyl-diphosphatase activity
D9Y32_RS11735	COG1408	metallophosphoesterase
D9Y32_RS11740	COG0726	polysaccharide deacetylase
D9Y32_RS11745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9Y32_RS11755	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9Y32_RS11800	COG2140	Oxalate decarboxylase
D9Y32_RS11805	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D9Y32_RS11810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D9Y32_RS11820	COG1510	regulation of RNA biosynthetic process
D9Y32_RS11825	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS11830	COG1454	alcohol dehydrogenase
D9Y32_RS11840	COG2318	DinB family
D9Y32_RS11850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9Y32_RS11855	COG0569	domain protein
D9Y32_RS11860	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D9Y32_RS11865	COG0457	Tetratricopeptide repeat
D9Y32_RS11880	COG3764	Sortase (surface protein transpeptidase)
D9Y32_RS11885	COG3859	Proton-coupled thiamine transporter YuaJ
D9Y32_RS11890	COG1609	Transcriptional regulator
D9Y32_RS12015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D9Y32_RS12020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9Y32_RS12025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9Y32_RS12030	COG0297	glycogen (starch) synthase activity
D9Y32_RS12035	COG0058	SHG alpha-glucan phosphorylase activity
D9Y32_RS12040	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9Y32_RS12045	COG1575	Belongs to the MenA family. Type 1 subfamily
D9Y32_RS12050	COG1169	isochorismate synthase
D9Y32_RS12055	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9Y32_RS12060	COG0596	Alpha beta hydrolase
D9Y32_RS12065	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9Y32_RS12070	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS12075	COG4948	Mandelate Racemase Muconate Lactonizing
D9Y32_RS12090	COG1294	oxidase, subunit
D9Y32_RS12095	COG1271	oxidase subunit
D9Y32_RS12100	COG0254	rRNA binding
D9Y32_RS12105	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9Y32_RS12110	COG0523	cobalamin synthesis protein
D9Y32_RS12115	COG0288	reversible hydration of carbon dioxide
D9Y32_RS12120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9Y32_RS12125	COG1854	S-ribosylhomocysteine lyase activity
D9Y32_RS12140	COG0783	Belongs to the Dps family
D9Y32_RS12145	COG4824	toxin secretion phage lysis holin
D9Y32_RS12160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9Y32_RS12165	COG1116	anion transmembrane transporter activity
D9Y32_RS12170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9Y32_RS12175	COG1506	peptidase
D9Y32_RS12185	COG1301	dicarboxylic acid transport
D9Y32_RS12190	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D9Y32_RS12195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9Y32_RS12200	COG0367	asparagine synthase
D9Y32_RS12205	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS12205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9Y32_RS12210	COG0671	phosphoesterase, PA-phosphatase related
D9Y32_RS12215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9Y32_RS12220	COG2267	carboxylic ester hydrolase activity
D9Y32_RS12230	COG1301	dicarboxylic acid transport
D9Y32_RS12235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9Y32_RS12240	COG1242	4 iron, 4 sulfur cluster binding
D9Y32_RS12250	COG1725	Transcriptional regulator
D9Y32_RS12255	COG1131	(ABC) transporter
D9Y32_RS12265	COG1136	(ABC) transporter
D9Y32_RS12270	COG0577	efflux transmembrane transporter activity
D9Y32_RS12275	COG2433	Pfam Transposase IS66
D9Y32_RS12285	COG2814	Major facilitator Superfamily
D9Y32_RS12295	COG0495	leucyl-tRNA aminoacylation
D9Y32_RS12300	COG0346	lactoylglutathione lyase activity
D9Y32_RS12305	COG0583	DNA-binding transcription factor activity
D9Y32_RS12315	COG1073	alpha beta
D9Y32_RS12320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9Y32_RS12325	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS12330	COG1653	transport
D9Y32_RS12335	COG2207	Transcriptional regulator
D9Y32_RS12340	COG4209	transmembrane transport
D9Y32_RS12345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9Y32_RS12350	COG1653	transport
D9Y32_RS12355	COG0673	inositol 2-dehydrogenase activity
D9Y32_RS12360	COG5578	integral membrane protein
D9Y32_RS12375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9Y32_RS12385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9Y32_RS12390	COG2081	HI0933 family
D9Y32_RS12395	COG2244	polysaccharide biosynthetic process
D9Y32_RS12400	COG1187	pseudouridine synthase activity
D9Y32_RS12405	COG1349	DNA-binding transcription factor activity
D9Y32_RS12410	COG2252	PERMEase
D9Y32_RS12415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9Y32_RS12430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9Y32_RS12435	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9Y32_RS12445	COG1597	lipid kinase activity
D9Y32_RS12450	COG1523	belongs to the glycosyl hydrolase 13 family
D9Y32_RS12465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9Y32_RS12470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS12475	COG0281	malic enzyme
D9Y32_RS12480	COG5584	Small secreted protein
D9Y32_RS12485	COG1363	Peptidase, m42
D9Y32_RS12495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS12500	COG4848	Belongs to the UPF0354 family
D9Y32_RS12505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9Y32_RS12510	COG1674	ftsk spoiiie
D9Y32_RS12520	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
D9Y32_RS12525	COG4980	gas vesicle protein
D9Y32_RS12530	COG3118	belongs to the thioredoxin family
D9Y32_RS12540	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9Y32_RS12540	COG1605	Chorismate mutase
D9Y32_RS12545	COG1609	Transcriptional regulator
D9Y32_RS12550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9Y32_RS12555	COG1360	Flagellar Motor Protein
D9Y32_RS12560	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9Y32_RS12565	COG0517	IMP dehydrogenase activity
D9Y32_RS12570	COG0454	-acetyltransferase
D9Y32_RS12575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9Y32_RS12580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9Y32_RS12585	COG1522	sequence-specific DNA binding
D9Y32_RS12590	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9Y32_RS12595	COG3152	Membrane
D9Y32_RS12610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9Y32_RS12620	COG1956	GAF domain-containing protein
D9Y32_RS12625	COG1309	transcriptional regulator
D9Y32_RS12630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9Y32_RS12635	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9Y32_RS12640	COG1114	Component of the transport system for branched-chain amino acids
D9Y32_RS12645	COG1104	cysteine desulfurase activity
D9Y32_RS12650	COG0301	tRNA thio-modification
D9Y32_RS12660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9Y32_RS12670	COG0477	Major facilitator Superfamily
D9Y32_RS12675	COG1566	PFAM secretion protein HlyD family protein
D9Y32_RS12680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9Y32_RS12685	COG0616	signal peptide processing
D9Y32_RS12690	COG1714	RDD family
D9Y32_RS12700	COG3874	Sporulation protein YtfJ
D9Y32_RS12705	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9Y32_RS12710	COG0827	DNA restriction-modification system
D9Y32_RS12715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9Y32_RS12720	COG0521	Mo-molybdopterin cofactor biosynthetic process
D9Y32_RS12725	COG0137	argininosuccinate synthase activity
D9Y32_RS12730	COG0165	Argininosuccinate lyase
D9Y32_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS12740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9Y32_RS12745	COG1695	Transcriptional regulator
D9Y32_RS12750	COG4109	DRTGG domain
D9Y32_RS12760	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9Y32_RS12780	COG0587	DNA-directed DNA polymerase activity
D9Y32_RS12785	COG0281	malic enzyme
D9Y32_RS12790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D9Y32_RS12795	COG0825	malonyl-CoA metabolic process
D9Y32_RS12800	COG0205	6-phosphofructokinase activity
D9Y32_RS12810	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9Y32_RS12815	COG0628	permease
D9Y32_RS12820	COG2707	UPF0756 membrane protein
D9Y32_RS12825	COG0372	Belongs to the citrate synthase family
D9Y32_RS12830	COG0538	isocitrate dehydrogenase activity
D9Y32_RS12835	COG0039	L-malate dehydrogenase activity
D9Y32_RS12840	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS12845	COG5002	protein histidine kinase activity
D9Y32_RS12850	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9Y32_RS12850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9Y32_RS12855	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9Y32_RS12860	COG1971	Probably functions as a manganese efflux pump
D9Y32_RS12865	COG0237	dephospho-CoA kinase activity
D9Y32_RS12875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9Y32_RS12880	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9Y32_RS12895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9Y32_RS12900	COG3611	Membrane attachment protein
D9Y32_RS12905	COG1484	DNA-dependent DNA replication
D9Y32_RS12910	COG0398	Pfam SNARE associated Golgi protein
D9Y32_RS12920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9Y32_RS12925	COG1011	Hydrolase
D9Y32_RS12935	COG3275	phosphorelay sensor kinase activity
D9Y32_RS12940	COG3279	Response regulator of the LytR AlgR family
D9Y32_RS12945	COG3540	Alkaline phosphatase
D9Y32_RS12955	COG1346	cytolysis
D9Y32_RS12960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9Y32_RS12965	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D9Y32_RS12970	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9Y32_RS12975	COG3326	Membrane
D9Y32_RS12985	COG1363	Peptidase, m42
D9Y32_RS12990	COG3507	Belongs to the glycosyl hydrolase 43 family
D9Y32_RS12995	COG2160	L-arabinose isomerase activity
D9Y32_RS13000	COG1069	ribulokinase activity
D9Y32_RS13005	COG0235	Class ii aldolase
D9Y32_RS13010	COG0371	Dehydrogenase
D9Y32_RS13015	COG1653	transport
D9Y32_RS13020	COG1175	transmembrane transport
D9Y32_RS13025	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS13040	COG1966	Carbon starvation protein
D9Y32_RS13050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9Y32_RS13055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9Y32_RS13060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9Y32_RS13060	COG0072	phenylalanine-tRNA ligase activity
D9Y32_RS13075	COG1137	ATPase activity
D9Y32_RS13100	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9Y32_RS13105	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9Y32_RS13110	COG1286	toxin biosynthetic process
D9Y32_RS13115	COG1796	DNA polymerase
D9Y32_RS13115	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9Y32_RS13120	COG1193	negative regulation of DNA recombination
D9Y32_RS13125	COG3766	membrane
D9Y32_RS13130	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS13135	COG1309	transcriptional regulator
D9Y32_RS13140	COG1024	Enoyl-CoA hydratase
D9Y32_RS13145	COG2086	electron transfer activity
D9Y32_RS13150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9Y32_RS13155	COG3118	belongs to the thioredoxin family
D9Y32_RS13160	COG0322	excinuclease ABC activity
D9Y32_RS13170	COG0527	aspartate kinase activity
D9Y32_RS13175	COG1719	4-vinyl reductase, 4VR
D9Y32_RS13180	COG2009	succinate dehydrogenase
D9Y32_RS13185	COG1053	succinate dehydrogenase
D9Y32_RS13190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9Y32_RS13195	COG0824	Thioesterase
D9Y32_RS13200	COG4221	oxidoreductase activity
D9Y32_RS13205	COG2197	response regulator
D9Y32_RS13210	COG1846	Transcriptional regulator
D9Y32_RS13215	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9Y32_RS13220	COG5401	PFAM Sporulation and spore germination
D9Y32_RS13225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D9Y32_RS13230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D9Y32_RS13235	COG0622	Phosphoesterase
D9Y32_RS13255	COG0457	Tetratricopeptide repeat
D9Y32_RS13300	COG1783	phage Terminase large subunit
D9Y32_RS13305	COG5518	Phage portal protein
D9Y32_RS13325	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9Y32_RS13335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9Y32_RS13340	COG0028	Belongs to the TPP enzyme family
D9Y32_RS13345	COG0440	acetolactate synthase activity
D9Y32_RS13350	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9Y32_RS13355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9Y32_RS13360	COG0473	3-isopropylmalate dehydrogenase activity
D9Y32_RS13365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9Y32_RS13370	COG0066	3-isopropylmalate dehydratase activity
D9Y32_RS13375	COG1477	protein flavinylation
D9Y32_RS13375	COG0457	Tetratricopeptide repeat
D9Y32_RS13380	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9Y32_RS13385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9Y32_RS13390	COG0470	DNA polymerase III
D9Y32_RS13390	COG1067	ATP-dependent peptidase activity
D9Y32_RS13395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9Y32_RS13400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9Y32_RS13410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D9Y32_RS13415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9Y32_RS13420	COG0181	hydroxymethylbilane synthase activity
D9Y32_RS13425	COG1587	Uroporphyrinogen-III synthase
D9Y32_RS13430	COG0113	porphobilinogen synthase activity
D9Y32_RS13435	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9Y32_RS13440	COG1388	LysM domain
D9Y32_RS13445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9Y32_RS13455	COG0525	valine-tRNA ligase activity
D9Y32_RS13460	COG0285	dihydrofolate synthase activity
D9Y32_RS13465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9Y32_RS13475	COG0424	maF-like protein
D9Y32_RS13480	COG2003	Belongs to the UPF0758 family
D9Y32_RS13485	COG1077	Cell shape determining protein MreB Mrl
D9Y32_RS13495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9Y32_RS13500	COG0850	regulation of cytokinetic process
D9Y32_RS13505	COG2894	cell division
D9Y32_RS13510	COG0640	Transcriptional regulator
D9Y32_RS13515	COG3832	glyoxalase III activity
D9Y32_RS13520	COG0739	heme binding
D9Y32_RS13525	COG1994	Peptidase M50
D9Y32_RS13530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9Y32_RS13535	COG2868	ribosomal protein
D9Y32_RS13540	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9Y32_RS13545	COG3290	protein histidine kinase activity
D9Y32_RS13550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9Y32_RS13555	COG4492	Belongs to the UPF0735 family
D9Y32_RS13560	COG0077	Prephenate dehydratase
D9Y32_RS13565	COG1827	regulation of RNA biosynthetic process
D9Y32_RS13570	COG1104	cysteine desulfurase activity
D9Y32_RS13575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9Y32_RS13580	COG0157	Belongs to the NadC ModD family
D9Y32_RS13585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D9Y32_RS13590	COG1388	LysM domain
D9Y32_RS13600	COG0217	transcriptional regulatory protein
D9Y32_RS13615	COG4195	phage-related replication protein
D9Y32_RS13620	COG2318	DinB family
D9Y32_RS13630	COG2112	serine threonine protein kinase
D9Y32_RS13640	COG0632	four-way junction helicase activity
D9Y32_RS13645	COG2255	four-way junction helicase activity
D9Y32_RS13655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9Y32_RS13660	COG0343	queuine tRNA-ribosyltransferase activity
D9Y32_RS13665	COG1862	Preprotein translocase
D9Y32_RS13675	COG2323	membrane
D9Y32_RS13680	COG2244	polysaccharide biosynthetic process
D9Y32_RS13690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9Y32_RS13690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9Y32_RS13695	COG5416	Lipopolysaccharide assembly protein A domain
D9Y32_RS13700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9Y32_RS13700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9Y32_RS13705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9Y32_RS13715	COG1490	D-aminoacyl-tRNA deacylase activity
D9Y32_RS13720	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS13720	COG3103	Sh3 type 3 domain protein
D9Y32_RS13720	COG4991	sh3 domain protein
D9Y32_RS13725	COG0124	histidyl-tRNA synthetase
D9Y32_RS13730	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9Y32_RS13740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9Y32_RS13745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9Y32_RS13750	COG1959	2 iron, 2 sulfur cluster binding
D9Y32_RS13755	COG1104	cysteine desulfurase activity
D9Y32_RS13760	COG0482	sulfurtransferase activity
D9Y32_RS13765	COG0457	Tetratricopeptide repeat
D9Y32_RS13770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9Y32_RS13775	COG3881	PFAM PRC-barrel domain
D9Y32_RS13790	COG0628	permease
D9Y32_RS13795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9Y32_RS13800	COG4472	Bacterial protein of unknown function (DUF965)
D9Y32_RS13805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9Y32_RS13810	COG3906	Belongs to the UPF0473 family
D9Y32_RS13815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9Y32_RS13820	COG4122	O-methyltransferase activity
D9Y32_RS13825	COG0826	peptidase U32
D9Y32_RS13830	COG0826	peptidase U32
D9Y32_RS13835	COG0572	uridine kinase
D9Y32_RS13840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9Y32_RS13845	COG0768	penicillin binding
D9Y32_RS13860	COG2226	methyltransferase
D9Y32_RS13865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9Y32_RS13870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9Y32_RS13875	COG0626	cystathionine gamma-synthase activity
D9Y32_RS13900	COG2226	methyltransferase
D9Y32_RS13905	COG1404	Belongs to the peptidase S8 family
D9Y32_RS13910	COG1309	transcriptional regulator
D9Y32_RS13915	COG2124	cytochrome p450
D9Y32_RS13915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9Y32_RS13925	COG2814	Major facilitator Superfamily
D9Y32_RS13930	COG0583	DNA-binding transcription factor activity
D9Y32_RS13935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS13945	COG1587	Uroporphyrinogen-III synthase
D9Y32_RS13950	COG3340	Belongs to the peptidase S51 family
D9Y32_RS13955	COG1733	regulation of RNA biosynthetic process
D9Y32_RS13960	COG2814	Major facilitator Superfamily
D9Y32_RS13965	COG0656	L-ascorbic acid biosynthetic process
D9Y32_RS13970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9Y32_RS13975	COG2169	Transcriptional regulator
D9Y32_RS13995	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9Y32_RS13995	COG3933	PFAM sigma-54 factor interaction domain-containing protein
D9Y32_RS14000	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS14005	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS14010	COG3715	PTS system
D9Y32_RS14015	COG3716	PTS system mannose fructose sorbose family IID component
D9Y32_RS14020	COG1621	beta-fructofuranosidase activity
D9Y32_RS14025	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS14040	COG0730	response to heat
D9Y32_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS14080	COG4608	Belongs to the ABC transporter superfamily
D9Y32_RS14085	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS14090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9Y32_RS14095	COG0601	transmembrane transport
D9Y32_RS14100	COG0747	negative chemotaxis
D9Y32_RS14105	COG0492	ferredoxin-NADP+ reductase activity
D9Y32_RS14110	COG2197	response regulator
D9Y32_RS14115	COG4585	Histidine kinase
D9Y32_RS14120	COG3239	Fatty acid desaturase
D9Y32_RS14125	COG1733	regulation of RNA biosynthetic process
D9Y32_RS14130	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9Y32_RS14135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9Y32_RS14140	COG0113	porphobilinogen synthase activity
D9Y32_RS14145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9Y32_RS14190	COG1937	Protein conserved in bacteria
D9Y32_RS14195	COG2210	Belongs to the sulfur carrier protein TusA family
D9Y32_RS14200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9Y32_RS14200	COG0425	Belongs to the sulfur carrier protein TusA family
D9Y32_RS14205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS14205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9Y32_RS14210	COG0425	Belongs to the sulfur carrier protein TusA family
D9Y32_RS14215	COG0730	response to heat
D9Y32_RS14220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS14225	COG4585	Histidine kinase
D9Y32_RS14230	COG2197	response regulator
D9Y32_RS14245	COG4978	Transcriptional regulator
D9Y32_RS14245	COG0789	Transcriptional regulator
D9Y32_RS14265	COG0251	oxidation-reduction process
D9Y32_RS14270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9Y32_RS14280	COG0251	oxidation-reduction process
D9Y32_RS14305	COG1247	-acetyltransferase
D9Y32_RS14320	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS14345	COG2427	Protein of unknown function (DUF1641)
D9Y32_RS14350	COG3383	formate dehydrogenase (NAD+) activity
D9Y32_RS14355	COG5609	conserved protein (DUF2294)
D9Y32_RS14360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9Y32_RS14365	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS14375	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9Y32_RS14380	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9Y32_RS14385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D9Y32_RS14390	COG1534	Rna-binding protein
D9Y32_RS14395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9Y32_RS14400	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9Y32_RS14405	COG0799	negative regulation of ribosome biogenesis
D9Y32_RS14410	COG2226	methyltransferase
D9Y32_RS14415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9Y32_RS14420	COG1596	polysaccharide export
D9Y32_RS14420	COG1555	photosystem II stabilization
D9Y32_RS14425	COG2131	deaminase
D9Y32_RS14430	COG0658	competence protein
D9Y32_RS14430	COG2333	competence protein COMEC
D9Y32_RS14440	COG1466	dna polymerase III delta subunit
D9Y32_RS14445	COG0268	Binds directly to 16S ribosomal RNA
D9Y32_RS14450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
D9Y32_RS14455	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS14465	COG0481	GTPase activity
D9Y32_RS14470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9Y32_RS14475	COG1420	regulation of RNA biosynthetic process
D9Y32_RS14480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9Y32_RS14485	COG0443	Heat shock 70 kDa protein
D9Y32_RS14490	COG0484	heat shock protein binding
D9Y32_RS14495	COG2264	protein methyltransferase activity
D9Y32_RS14500	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9Y32_RS14505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9Y32_RS14510	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9Y32_RS14515	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9Y32_RS14520	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9Y32_RS14525	COG1610	YqeY-like protein
D9Y32_RS14530	COG1030	water channel activity
D9Y32_RS14535	COG4864	UPF0365 protein
D9Y32_RS14550	COG0561	phosphatase activity
D9Y32_RS14555	COG1702	phosphate starvation-inducible protein PhoH
D9Y32_RS14560	COG1480	7TM receptor with intracellular HD hydrolase
D9Y32_RS14565	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D9Y32_RS14570	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9Y32_RS14575	COG0295	cytidine deaminase activity
D9Y32_RS14580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9Y32_RS14590	COG1381	Involved in DNA repair and RecF pathway recombination
D9Y32_RS14595	COG0752	glycyl-tRNA synthetase alpha subunit
D9Y32_RS14600	COG0751	glycine-tRNA ligase activity
D9Y32_RS14605	COG0517	IMP dehydrogenase activity
D9Y32_RS14610	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9Y32_RS14615	COG1671	Belongs to the UPF0178 family
D9Y32_RS14620	COG0358	DNA primase activity
D9Y32_RS14625	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9Y32_RS14630	COG2010	Cytochrome c
D9Y32_RS14645	COG5444	nuclease activity
D9Y32_RS14720	COG3546	catalase activity
D9Y32_RS14745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9Y32_RS14760	COG2323	membrane
D9Y32_RS14765	COG2323	membrane
D9Y32_RS14770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9Y32_RS14775	COG2323	membrane
D9Y32_RS14780	COG2027	D-alanyl-D-alanine carboxypeptidase
D9Y32_RS14790	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D9Y32_RS14795	COG2404	hydrolase activity, acting on ester bonds
D9Y32_RS14800	COG1649	PFAM Uncharacterised BCR, COG1649
D9Y32_RS14815	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
D9Y32_RS14825	COG0640	Transcriptional regulator
D9Y32_RS14830	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9Y32_RS14835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9Y32_RS14840	COG1609	Transcriptional regulator
D9Y32_RS14850	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D9Y32_RS14860	COG1312	Catalyzes the dehydration of D-mannonate
D9Y32_RS14870	COG1725	Transcriptional regulator
D9Y32_RS14885	COG3711	transcriptional antiterminator
D9Y32_RS14885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS14910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS14910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS14910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS14915	COG1482	cell wall glycoprotein biosynthetic process
D9Y32_RS14920	COG1960	acyl-CoA dehydrogenase activity
D9Y32_RS14925	COG2084	Dehydrogenase
D9Y32_RS14930	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS14935	COG1024	Enoyl-CoA hydratase
D9Y32_RS14960	COG0789	Transcriptional regulator
D9Y32_RS14965	COG1064	alcohol dehydrogenase
D9Y32_RS14970	COG1114	Component of the transport system for branched-chain amino acids
D9Y32_RS14975	COG3420	alginic acid biosynthetic process
D9Y32_RS14990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9Y32_RS15000	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
D9Y32_RS15010	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
D9Y32_RS15030	COG2223	nitrite transmembrane transporter activity
D9Y32_RS15035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9Y32_RS15045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9Y32_RS15050	COG0535	radical SAM domain protein
D9Y32_RS15065	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
D9Y32_RS15070	COG1140	nitrate reductase beta subunit
D9Y32_RS15075	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
D9Y32_RS15080	COG2181	nitrate reductase activity
D9Y32_RS15090	COG1115	amino acid carrier protein
D9Y32_RS15110	COG2160	L-arabinose isomerase activity
D9Y32_RS15125	COG1609	Transcriptional regulator
D9Y32_RS15130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9Y32_RS15135	COG0187	DNA topoisomerase II activity
D9Y32_RS15145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9Y32_RS15150	COG4841	protein insertion into membrane
D9Y32_RS15175	COG0824	Thioesterase
D9Y32_RS15195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS15200	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9Y32_RS15215	COG0071	Belongs to the small heat shock protein (HSP20) family
D9Y32_RS15225	COG4846	Membrane protein involved in cytochrome C biogenesis
D9Y32_RS15230	COG2201	protein-glutamate methylesterase activity
D9Y32_RS15235	COG0785	Cytochrome C biogenesis protein
D9Y32_RS15245	COG3763	UPF0154 protein
D9Y32_RS15255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9Y32_RS15260	COG4224	UPF0291 protein
D9Y32_RS15265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9Y32_RS15270	COG1388	LysM domain
D9Y32_RS15275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9Y32_RS15280	COG3209	COG3209 Rhs family protein
D9Y32_RS15300	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS15305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9Y32_RS15310	COG0346	lactoylglutathione lyase activity
D9Y32_RS15315	COG0778	Nitroreductase
D9Y32_RS15320	COG1846	Transcriptional regulator
D9Y32_RS15345	COG3546	catalase activity
D9Y32_RS15365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9Y32_RS15370	COG2076	Multidrug Resistance protein
D9Y32_RS15375	COG2076	Multidrug Resistance protein
D9Y32_RS15380	COG1309	transcriptional regulator
D9Y32_RS15420	COG1073	alpha beta
D9Y32_RS15460	COG0174	glutamine synthetase
D9Y32_RS15465	COG0789	Transcriptional regulator
D9Y32_RS15470	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9Y32_RS15475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9Y32_RS15480	COG0464	growth
D9Y32_RS15530	COG1309	transcriptional regulator
D9Y32_RS15565	COG0697	spore germination
D9Y32_RS15570	COG1802	Transcriptional regulator
D9Y32_RS15580	COG0822	iron-sulfur transferase activity
D9Y32_RS15590	COG4112	unkown
D9Y32_RS15595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9Y32_RS15600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9Y32_RS15605	COG1780	Probably involved in ribonucleotide reductase function
D9Y32_RS15620	COG1923	regulation of RNA biosynthetic process
D9Y32_RS15625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9Y32_RS15640	COG2076	Multidrug Resistance protein
D9Y32_RS15645	COG2076	Multidrug Resistance protein
D9Y32_RS15650	COG1764	response to oxidative stress
D9Y32_RS15660	COG0702	epimerase
D9Y32_RS15665	COG3631	Ketosteroid isomerase-related protein
D9Y32_RS15670	COG1309	transcriptional regulator
D9Y32_RS15675	COG1388	LysM domain
D9Y32_RS15675	COG3858	chitin binding
D9Y32_RS15685	COG5577	PFAM Coat F domain
D9Y32_RS15690	COG0531	amino acid
D9Y32_RS15695	COG1819	glycosyl
D9Y32_RS15700	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9Y32_RS15705	COG0398	Pfam SNARE associated Golgi protein
D9Y32_RS15720	COG2267	carboxylic ester hydrolase activity
D9Y32_RS15725	COG2814	Major facilitator Superfamily
D9Y32_RS15730	COG3263	regulation of cellular component size
D9Y32_RS15735	COG3619	membrane
D9Y32_RS15755	COG1247	-acetyltransferase
D9Y32_RS15765	COG0523	cobalamin synthesis protein
D9Y32_RS15785	COG5444	nuclease activity
D9Y32_RS15790	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D9Y32_RS15795	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9Y32_RS15800	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9Y32_RS15810	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9Y32_RS15815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9Y32_RS15820	COG0156	8-amino-7-oxononanoate synthase activity
D9Y32_RS15825	COG1063	alcohol dehydrogenase
D9Y32_RS15835	COG2359	stage V sporulation protein S
D9Y32_RS15840	COG1692	metallophosphoesterase
D9Y32_RS15845	COG1418	mRNA catabolic process
D9Y32_RS15855	COG1058	Belongs to the CinA family
D9Y32_RS15855	COG1546	Belongs to the CinA family
D9Y32_RS15860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9Y32_RS15865	COG1426	Protein conserved in bacteria
D9Y32_RS15880	COG0300	oxidoreductase activity
D9Y32_RS15885	COG0612	Peptidase, M16
D9Y32_RS15890	COG0612	Peptidase, M16
D9Y32_RS15895	COG2814	Major facilitator Superfamily
D9Y32_RS15900	COG2188	Transcriptional regulator
D9Y32_RS15905	COG1674	ftsk spoiiie
D9Y32_RS15905	COG4980	gas vesicle protein
D9Y32_RS15915	COG0740	serine-type endopeptidase activity
D9Y32_RS15920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9Y32_RS15930	COG0527	aspartate kinase activity
D9Y32_RS15935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9Y32_RS15940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9Y32_RS15945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9Y32_RS15950	COG1873	PFAM PRC-barrel domain
D9Y32_RS15955	COG0612	Peptidase, M16
D9Y32_RS15960	COG0726	polysaccharide deacetylase
D9Y32_RS15965	COG1185	polyribonucleotide nucleotidyltransferase activity
D9Y32_RS15970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9Y32_RS15975	COG0196	riboflavin kinase activity
D9Y32_RS15980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D9Y32_RS15985	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D9Y32_RS15990	COG1550	Protein conserved in bacteria
D9Y32_RS15995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D9Y32_RS16000	COG1358	cellular component organization or biogenesis
D9Y32_RS16005	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9Y32_RS16010	COG0195	Participates in both transcription termination and antitermination
D9Y32_RS16015	COG0779	Required for maturation of 30S ribosomal subunits
D9Y32_RS16045	COG2176	DNA-directed DNA polymerase activity
D9Y32_RS16050	COG0442	prolyl-tRNA aminoacylation
D9Y32_RS16055	COG0750	zinc metalloprotease
D9Y32_RS16060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9Y32_RS16065	COG4589	Belongs to the CDS family
D9Y32_RS16070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9Y32_RS16075	COG0233	cytoplasmic translational termination
D9Y32_RS16080	COG0528	UMP kinase activity
D9Y32_RS16085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D9Y32_RS16090	COG0052	Belongs to the universal ribosomal protein uS2 family
D9Y32_RS16100	COG1191	sigma factor activity
D9Y32_RS16105	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9Y32_RS16115	COG0835	chemotaxis
D9Y32_RS16120	COG2198	Histidine kinase
D9Y32_RS16120	COG0643	Histidine kinase
D9Y32_RS16125	COG2201	protein-glutamate methylesterase activity
D9Y32_RS16130	COG0455	bacterial-type flagellum organization
D9Y32_RS16135	COG1419	protein localization to endoplasmic reticulum
D9Y32_RS16140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9Y32_RS16145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9Y32_RS16150	COG1684	flagellar biosynthetic protein fliR
D9Y32_RS16155	COG1987	bacterial-type flagellum assembly
D9Y32_RS16160	COG1338	Plays a role in the flagellum-specific transport system
D9Y32_RS16165	COG3190	flagellar
D9Y32_RS16170	COG2201	protein-glutamate methylesterase activity
D9Y32_RS16175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9Y32_RS16175	COG1776	CheC inhibitor of MCP methylation
D9Y32_RS16180	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9Y32_RS16185	COG1580	Controls the rotational direction of flagella during chemotaxis
D9Y32_RS16190	COG1582	Flagellar protein (FlbD)
D9Y32_RS16195	COG4786	Flagellar basal body rod
D9Y32_RS16200	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9Y32_RS16205	COG3144	bacterial-type flagellum assembly
D9Y32_RS16215	COG2882	bacterial-type flagellum organization
D9Y32_RS16220	COG1157	protein secretion by the type III secretion system
D9Y32_RS16225	COG1317	bacterial-type flagellum organization
D9Y32_RS16230	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9Y32_RS16235	COG1766	The M ring may be actively involved in energy transduction
D9Y32_RS16240	COG1677	Flagellar hook-basal body complex protein FliE
D9Y32_RS16245	COG1558	bacterial-type flagellum-dependent cell motility
D9Y32_RS16250	COG1815	bacterial-type flagellum-dependent cell motility
D9Y32_RS16255	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9Y32_RS16260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9Y32_RS16265	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9Y32_RS16270	COG4974	Belongs to the 'phage' integrase family
D9Y32_RS16275	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
D9Y32_RS16280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9Y32_RS16285	COG0758	DNA mediated transformation
D9Y32_RS16290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9Y32_RS16295	COG0045	succinate-CoA ligase (ADP-forming) activity
D9Y32_RS16300	COG2257	FlhB HrpN YscU SpaS Family
D9Y32_RS16310	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9Y32_RS16315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9Y32_RS16320	COG0335	large ribosomal subunit rRNA binding
D9Y32_RS16325	COG0336	Belongs to the RNA methyltransferase TrmD family
D9Y32_RS16330	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9Y32_RS16340	COG1837	Belongs to the UPF0109 family
D9Y32_RS16345	COG0228	four-way junction DNA binding
D9Y32_RS16355	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9Y32_RS16360	COG0552	protein localization to endoplasmic reticulum
D9Y32_RS16365	COG1196	nuclear chromosome segregation
D9Y32_RS16370	COG0571	ribonuclease III activity
D9Y32_RS16375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9Y32_RS16380	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS16385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9Y32_RS16390	COG0416	fatty acid biosynthetic process
D9Y32_RS16395	COG1349	DNA-binding transcription factor activity
D9Y32_RS16400	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9Y32_RS16405	COG1760	l-serine dehydratase
D9Y32_RS16410	COG1760	l-serine dehydratase
D9Y32_RS16415	COG1461	Dihydroxyacetone kinase
D9Y32_RS16420	COG1302	Protein conserved in bacteria
D9Y32_RS16425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9Y32_RS16435	COG1564	THIamine pyrophosphokinase
D9Y32_RS16440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9Y32_RS16445	COG1162	GTPase activity
D9Y32_RS16450	COG2815	serine threonine protein kinase
D9Y32_RS16450	COG0515	serine threonine protein kinase
D9Y32_RS16455	COG0631	protein serine/threonine phosphatase activity
D9Y32_RS16460	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9Y32_RS16465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9Y32_RS16465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9Y32_RS16470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9Y32_RS16475	COG0242	peptide deformylase activity
D9Y32_RS16480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9Y32_RS16485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9Y32_RS16490	COG1758	RNA polymerase activity
D9Y32_RS16495	COG0194	GDP metabolic process
D9Y32_RS16500	COG2052	Domain of unknown function (DUF370)
D9Y32_RS16505	COG1561	YicC-like family, N-terminal region
D9Y32_RS16510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9Y32_RS16520	COG1648	precorrin-2 dehydrogenase activity
D9Y32_RS16525	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
D9Y32_RS16530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D9Y32_RS16535	COG0529	Catalyzes the synthesis of activated sulfate
D9Y32_RS16540	COG2046	Belongs to the sulfate adenylyltransferase family
D9Y32_RS16545	COG0306	phosphate transporter
D9Y32_RS16550	COG0175	sulfate reduction
D9Y32_RS16560	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D9Y32_RS16565	COG0284	orotidine-5'-phosphate decarboxylase activity
D9Y32_RS16570	COG0167	dihydroorotate dehydrogenase activity
D9Y32_RS16575	COG0543	2 iron, 2 sulfur cluster binding
D9Y32_RS16580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9Y32_RS16585	COG0505	Belongs to the CarA family
D9Y32_RS16590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9Y32_RS16595	COG0540	Belongs to the ATCase OTCase family
D9Y32_RS16600	COG2233	PERMEase
D9Y32_RS16605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9Y32_RS16610	COG0564	pseudouridine synthase activity
D9Y32_RS16615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9Y32_RS16620	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9Y32_RS16625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9Y32_RS16630	COG3599	regulation of cell shape
D9Y32_RS16635	COG2302	S4 RNA-binding domain
D9Y32_RS16640	COG0762	integral membrane protein
D9Y32_RS16645	COG1799	cell septum assembly
D9Y32_RS16650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9Y32_RS16655	COG1496	oxidoreductase activity
D9Y32_RS16660	COG1873	PFAM PRC-barrel domain
D9Y32_RS16665	COG0500	methyltransferase
D9Y32_RS16670	COG1119	ATPase activity
D9Y32_RS16675	COG1191	sigma factor activity
D9Y32_RS16680	COG1191	sigma factor activity
D9Y32_RS16690	COG1404	Belongs to the peptidase S8 family
D9Y32_RS16690	COG4412	M6 family metalloprotease domain protein
D9Y32_RS16705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9Y32_RS16710	COG0849	cell division
D9Y32_RS16715	COG3856	small basic protein
D9Y32_RS16720	COG3879	Bacterial protein of unknown function (DUF881)
D9Y32_RS16725	COG3879	Bacterial protein of unknown function (DUF881)
D9Y32_RS16735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9Y32_RS16740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9Y32_RS16745	COG0772	Belongs to the SEDS family
D9Y32_RS16750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9Y32_RS16755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9Y32_RS16760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9Y32_RS16775	COG0768	penicillin binding
D9Y32_RS16780	COG4839	cell division protein FtsL
D9Y32_RS16785	COG0275	rRNA processing
D9Y32_RS16790	COG2001	Belongs to the MraZ family
D9Y32_RS16795	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
D9Y32_RS16800	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9Y32_RS16805	COG0454	-acetyltransferase
D9Y32_RS16815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9Y32_RS16820	COG1399	metal-binding, possibly nucleic acid-binding protein
D9Y32_RS16825	COG1323	Belongs to the UPF0348 family
D9Y32_RS16830	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9Y32_RS16835	COG3314	Sporulation integral membrane protein YlbJ
D9Y32_RS16840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9Y32_RS16845	COG0742	ribosomal rna small subunit methyltransferase
D9Y32_RS16850	COG4471	UPF0298 protein
D9Y32_RS16855	COG3679	Belongs to the UPF0342 family
D9Y32_RS16870	COG2340	Cysteine-rich secretory protein family
D9Y32_RS16875	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9Y32_RS16885	COG3336	cytochrome c oxidase
D9Y32_RS16890	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D9Y32_RS16895	COG1845	cytochrome c oxidase, subunit III
D9Y32_RS16900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9Y32_RS16905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9Y32_RS16905	COG2010	Cytochrome c
D9Y32_RS16910	COG0109	protoheme IX farnesyltransferase activity
D9Y32_RS16915	COG1612	heme a metabolic process
D9Y32_RS16920	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9Y32_RS16925	COG0772	Belongs to the SEDS family
D9Y32_RS16930	COG4838	Belongs to the UPF0358 family
D9Y32_RS16935	COG2066	Belongs to the glutaminase family
D9Y32_RS16940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9Y32_RS16955	COG4896	Protein conserved in bacteria
D9Y32_RS16960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9Y32_RS16965	COG1846	Transcriptional regulator
D9Y32_RS16975	COG1217	gtp-binding protein TYPA
D9Y32_RS16990	COG1595	DNA-templated transcription, initiation
D9Y32_RS17010	COG0483	inositol monophosphate 1-phosphatase activity
D9Y32_RS17020	COG4493	Belongs to the UPF0637 family
D9Y32_RS17025	COG4476	Belongs to the UPF0223 family
D9Y32_RS17035	COG1982	Orn Lys Arg decarboxylase major
D9Y32_RS17045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS17050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9Y32_RS17055	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9Y32_RS17060	COG0022	dehydrogenase e1 component
D9Y32_RS17065	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9Y32_RS17070	COG0497	DNA recombination
D9Y32_RS17080	COG0242	peptide deformylase activity
D9Y32_RS17085	COG0561	phosphatase activity
D9Y32_RS17090	COG5503	Protein of unknown function (DUF1447)
D9Y32_RS17095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9Y32_RS17100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9Y32_RS17105	COG0569	domain protein
D9Y32_RS17110	COG3852	Histidine kinase
D9Y32_RS17115	COG2002	toxin-antitoxin pair type II binding
D9Y32_RS17120	COG1077	Cell shape determining protein MreB Mrl
D9Y32_RS17130	COG2309	aminopeptidase activity
D9Y32_RS17140	COG0488	(ABC) transporter
D9Y32_RS17160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS17160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9Y32_RS17160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS17165	COG1105	Belongs to the carbohydrate kinase PfkB family
D9Y32_RS17170	COG1349	DNA-binding transcription factor activity
D9Y32_RS17175	COG0577	efflux transmembrane transporter activity
D9Y32_RS17180	COG1136	(ABC) transporter
D9Y32_RS17185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D9Y32_RS17195	COG1132	(ABC) transporter
D9Y32_RS17200	COG1132	(ABC) transporter
D9Y32_RS17210	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D9Y32_RS17215	COG0314	molybdopterin synthase activity
D9Y32_RS17220	COG1763	Mo-molybdopterin cofactor biosynthetic process
D9Y32_RS17225	COG0303	'Molybdopterin
D9Y32_RS17230	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9Y32_RS17235	COG0746	molybdenum cofactor guanylyltransferase activity
D9Y32_RS17250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS17255	COG0450	alkyl hydroperoxide reductase
D9Y32_RS17265	COG1473	amidohydrolase
D9Y32_RS17270	COG2171	N-acyltransferase activity
D9Y32_RS17285	COG0716	FMN binding
D9Y32_RS17290	COG0583	DNA-binding transcription factor activity
D9Y32_RS17295	COG0517	IMP dehydrogenase activity
D9Y32_RS17305	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
D9Y32_RS17310	COG4703	Protein of unknown function (DUF1797)
D9Y32_RS17320	COG2200	EAL domain
D9Y32_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS17330	COG1408	metallophosphoesterase
D9Y32_RS17340	COG1376	ErfK ybiS ycfS ynhG family protein
D9Y32_RS17345	COG2814	Major facilitator Superfamily
D9Y32_RS17355	COG0835	chemotaxis
D9Y32_RS17355	COG0784	Response regulator, receiver
D9Y32_RS17365	COG1714	RDD family
D9Y32_RS17370	COG0436	Aminotransferase
D9Y32_RS17375	COG4191	Histidine kinase
D9Y32_RS17380	COG0768	penicillin binding
D9Y32_RS17385	COG2340	Cysteine-rich secretory protein family
D9Y32_RS17390	COG2084	Dehydrogenase
D9Y32_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS17400	COG0840	transmembrane signaling receptor activity
D9Y32_RS17405	COG0456	acetyltransferase
D9Y32_RS17410	COG1533	DNA photolyase activity
D9Y32_RS17420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D9Y32_RS17425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9Y32_RS17430	COG1263	PTS System
D9Y32_RS17430	COG2190	(PTS) system
D9Y32_RS17430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9Y32_RS17435	COG3711	transcriptional antiterminator
D9Y32_RS17440	COG1609	Transcriptional regulator
D9Y32_RS17450	COG0006	proline dipeptidase activity
D9Y32_RS17455	COG2217	Heavy metal translocating P-type atpase
D9Y32_RS17460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS17465	COG2244	polysaccharide biosynthetic process
D9Y32_RS17470	COG3773	Cell wall hydrolase
D9Y32_RS17480	COG4873	Protein conserved in bacteria
D9Y32_RS17510	COG3655	Transcriptional regulator
D9Y32_RS17515	COG3739	integral membrane protein
D9Y32_RS17530	COG0582	viral genome integration into host DNA
D9Y32_RS17545	COG3409	Peptidoglycan-binding domain 1 protein
D9Y32_RS17545	COG1388	LysM domain
D9Y32_RS17545	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS17665	COG0582	viral genome integration into host DNA
D9Y32_RS17745	COG5444	nuclease activity
D9Y32_RS17795	COG4974	Belongs to the 'phage' integrase family
D9Y32_RS17805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9Y32_RS17810	COG0602	queuosine metabolic process
D9Y32_RS17815	COG0720	synthase
D9Y32_RS17820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D9Y32_RS17825	COG3949	Membrane
D9Y32_RS17830	COG0542	response to heat
D9Y32_RS17835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9Y32_RS17840	COG1360	Flagellar Motor Protein
D9Y32_RS17845	COG1846	Transcriptional regulator
D9Y32_RS17850	COG3852	Histidine kinase
D9Y32_RS17860	COG3339	Conserved Protein
D9Y32_RS17865	COG0346	lactoylglutathione lyase activity
D9Y32_RS17870	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9Y32_RS17875	COG0235	Class ii aldolase
D9Y32_RS17875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9Y32_RS17880	COG1850	ribulose-bisphosphate carboxylase activity
D9Y32_RS17885	COG0436	Aminotransferase
D9Y32_RS17890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9Y32_RS17895	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9Y32_RS17900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9Y32_RS17905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9Y32_RS17910	COG5002	protein histidine kinase activity
D9Y32_RS17915	COG3594	Acyltransferase
D9Y32_RS17930	COG0768	penicillin binding
D9Y32_RS17935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9Y32_RS17940	COG0501	Belongs to the peptidase M48B family
D9Y32_RS17960	COG1191	sigma factor activity
D9Y32_RS17965	COG0861	Integral membrane protein TerC family
D9Y32_RS17970	COG0586	Pfam SNARE associated Golgi protein
D9Y32_RS17975	COG3300	MHYT domain
D9Y32_RS17975	COG5001	Diguanylate cyclase
D9Y32_RS17980	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9Y32_RS17985	COG3285	dna ligase
D9Y32_RS17985	COG1793	dna ligase
D9Y32_RS17990	COG1846	Transcriptional regulator
D9Y32_RS18005	COG0789	Transcriptional regulator
D9Y32_RS18015	COG2239	Acts as a magnesium transporter
D9Y32_RS18025	COG1404	Belongs to the peptidase S8 family
D9Y32_RS18045	COG0406	alpha-ribazole phosphatase activity
D9Y32_RS18050	COG0590	tRNA wobble adenosine to inosine editing
D9Y32_RS18060	COG1764	response to oxidative stress
D9Y32_RS18065	COG1846	Transcriptional regulator
D9Y32_RS18075	COG1764	response to oxidative stress
D9Y32_RS18080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9Y32_RS18085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9Y32_RS18090	COG0788	formyltetrahydrofolate deformylase activity
D9Y32_RS18095	COG2076	Multidrug Resistance protein
D9Y32_RS18100	COG2076	Multidrug Resistance protein
D9Y32_RS18105	COG2318	DinB family
D9Y32_RS18125	COG3866	Pectate lyase
D9Y32_RS18130	COG2323	membrane
D9Y32_RS18135	COG1607	acyl-coa hydrolase
D9Y32_RS18140	COG1834	amidinotransferase
D9Y32_RS18145	COG4608	Belongs to the ABC transporter superfamily
D9Y32_RS18150	COG0791	NLP P60 protein
D9Y32_RS18155	COG4948	Mandelate Racemase Muconate Lactonizing
D9Y32_RS18160	COG1619	proteins homologs of microcin C7 resistance protein MccF
D9Y32_RS18165	COG4166	transmembrane transport
D9Y32_RS18170	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS18175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9Y32_RS18180	COG0601	transmembrane transport
D9Y32_RS18185	COG2362	D-Aminopeptidase
D9Y32_RS18190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9Y32_RS18195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9Y32_RS18205	COG0346	lactoylglutathione lyase activity
D9Y32_RS18210	COG0531	amino acid
D9Y32_RS18215	COG0395	ABC-type sugar transport system, permease component
D9Y32_RS18220	COG4209	transmembrane transport
D9Y32_RS18225	COG1653	transport
D9Y32_RS18235	COG1874	Beta-galactosidase
D9Y32_RS18240	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS18245	COG0667	Aldo Keto reductase
D9Y32_RS18250	COG3401	FG-GAP repeat protein
D9Y32_RS18255	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS18265	COG3401	FG-GAP repeat protein
D9Y32_RS18270	COG5578	integral membrane protein
D9Y32_RS18280	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS18285	COG2207	Transcriptional regulator
D9Y32_RS18290	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
D9Y32_RS18295	COG1175	transmembrane transport
D9Y32_RS18300	COG1653	transport
D9Y32_RS18305	COG2207	Transcriptional regulator
D9Y32_RS18305	COG4753	response regulator
D9Y32_RS18310	COG2972	Histidine kinase
D9Y32_RS18315	COG5578	integral membrane protein
D9Y32_RS18320	COG0405	Gamma-glutamyltransferase
D9Y32_RS18325	COG1392	Phosphate transport regulator
D9Y32_RS18330	COG0306	phosphate transporter
D9Y32_RS18345	COG2271	Major facilitator Superfamily
D9Y32_RS18350	COG1063	alcohol dehydrogenase
D9Y32_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS18360	COG1312	Catalyzes the dehydration of D-mannonate
D9Y32_RS18365	COG1063	alcohol dehydrogenase
D9Y32_RS18370	COG1802	Transcriptional regulator
D9Y32_RS18380	COG3594	Acyltransferase
D9Y32_RS18425	COG3778	Protein conserved in bacteria
D9Y32_RS18430	COG3299	homolog of phage Mu protein gp47
D9Y32_RS18435	COG3628	GPW Gp25 family protein
D9Y32_RS18445	COG4193	domain, Protein
D9Y32_RS18450	COG1652	LysM domain
D9Y32_RS18455	COG3953	SLT domain
D9Y32_RS18455	COG5412	phage tail tape measure protein
D9Y32_RS18505	COG4653	Phage capsid family
D9Y32_RS18510	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9Y32_RS18515	COG5518	Phage portal protein
D9Y32_RS18520	COG1783	phage Terminase large subunit
D9Y32_RS18525	COG3728	DNA packaging
D9Y32_RS18525	COG5484	DNA packaging
D9Y32_RS18530	COG1595	DNA-templated transcription, initiation
D9Y32_RS18545	COG1484	DNA-dependent DNA replication
D9Y32_RS18550	COG1522	sequence-specific DNA binding
D9Y32_RS18565	COG1396	sequence-specific DNA binding
D9Y32_RS18570	COG2856	Zn peptidase
D9Y32_RS18575	COG4195	phage-related replication protein
D9Y32_RS18600	COG1309	transcriptional regulator
D9Y32_RS18605	COG2814	Major facilitator Superfamily
D9Y32_RS18610	COG3584	3D domain protein
D9Y32_RS18610	COG1388	LysM domain
D9Y32_RS18620	COG0346	lactoylglutathione lyase activity
D9Y32_RS18625	COG0697	spore germination
D9Y32_RS18630	COG0583	DNA-binding transcription factor activity
D9Y32_RS18635	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D9Y32_RS18640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D9Y32_RS18645	COG0583	DNA-binding transcription factor activity
D9Y32_RS18655	COG0110	maltose O-acetyltransferase activity
D9Y32_RS18675	COG3507	Belongs to the glycosyl hydrolase 43 family
D9Y32_RS18680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9Y32_RS18695	COG5505	Protein of unknown function (DUF819)
D9Y32_RS18700	COG0626	cystathionine gamma-synthase activity
D9Y32_RS18705	COG0626	cystathionine gamma-synthase activity
D9Y32_RS18725	COG2382	esterase
D9Y32_RS18730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9Y32_RS18735	COG2153	protein acetylation
D9Y32_RS18740	COG2246	polysaccharide biosynthetic process
D9Y32_RS18745	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9Y32_RS18750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9Y32_RS18755	COG0586	Pfam SNARE associated Golgi protein
D9Y32_RS18765	COG0210	DNA helicase
D9Y32_RS18820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D9Y32_RS18825	COG0351	phosphomethylpyrimidine kinase
D9Y32_RS18830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D9Y32_RS18835	COG2022	thiamine diphosphate biosynthetic process
D9Y32_RS18840	COG2104	thiamine diphosphate biosynthetic process
D9Y32_RS18850	COG0352	thiamine-phosphate diphosphorylase activity
D9Y32_RS18860	COG0475	glutathione-regulated potassium exporter activity
D9Y32_RS18860	COG0569	domain protein
D9Y32_RS18870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9Y32_RS18875	COG0564	pseudouridine synthase activity
D9Y32_RS18880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9Y32_RS18885	COG2357	RelA SpoT domain protein
D9Y32_RS18895	COG4116	CYTH
D9Y32_RS18900	COG0741	lytic transglycosylase activity
D9Y32_RS18905	COG2346	COG2346, Truncated hemoglobins
D9Y32_RS18910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9Y32_RS18915	COG1164	Oligoendopeptidase f
D9Y32_RS18920	COG4469	Competence protein
D9Y32_RS18925	COG3290	protein histidine kinase activity
D9Y32_RS18930	COG4565	transcriptional regulatory protein
D9Y32_RS18950	COG4862	establishment of competence for transformation
D9Y32_RS18960	COG0861	Integral membrane protein TerC family
D9Y32_RS18965	COG1393	Belongs to the ArsC family
D9Y32_RS18970	COG0456	acetyltransferase
D9Y32_RS18975	COG4608	Belongs to the ABC transporter superfamily
D9Y32_RS18980	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS18985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9Y32_RS18990	COG0601	transmembrane transport
D9Y32_RS18995	COG4166	transmembrane transport
D9Y32_RS19005	COG0180	Tryptophanyl-tRNA synthetase
D9Y32_RS19020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9Y32_RS19025	COG0601	transmembrane transport
D9Y32_RS19130	COG0582	viral genome integration into host DNA
D9Y32_RS19190	COG1196	nuclear chromosome segregation
D9Y32_RS19190	COG0741	lytic transglycosylase activity
D9Y32_RS19190	COG0739	heme binding
D9Y32_RS19195	COG1196	nuclear chromosome segregation
D9Y32_RS19195	COG0741	lytic transglycosylase activity
D9Y32_RS19195	COG0739	heme binding
D9Y32_RS19200	COG0741	lytic transglycosylase activity
D9Y32_RS19200	COG1196	nuclear chromosome segregation
D9Y32_RS19200	COG0739	heme binding
D9Y32_RS19220	COG5434	Belongs to the glycosyl hydrolase 28 family
D9Y32_RS19225	COG5632	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS19250	COG0457	Tetratricopeptide repeat
D9Y32_RS19255	COG2814	Major facilitator Superfamily
D9Y32_RS19295	COG5444	nuclease activity
D9Y32_RS19300	COG4282	regulation of fungal-type cell wall biogenesis
D9Y32_RS19310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9Y32_RS19315	COG1509	lysine 2,3-aminomutase activity
D9Y32_RS19320	COG0456	acetyltransferase
D9Y32_RS19325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9Y32_RS19330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D9Y32_RS19335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9Y32_RS19340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D9Y32_RS19355	COG0456	acetyltransferase
D9Y32_RS19360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9Y32_RS19365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9Y32_RS19370	COG1846	Transcriptional regulator
D9Y32_RS19380	COG3706	GGDEF domain
D9Y32_RS19400	COG4698	Protein conserved in bacteria
D9Y32_RS19405	COG2755	lipolytic protein G-D-S-L family
D9Y32_RS19410	COG1999	signal sequence binding
D9Y32_RS19425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9Y32_RS19430	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D9Y32_RS19435	COG1272	protein, Hemolysin III
D9Y32_RS19440	COG0204	Acyl-transferase
D9Y32_RS19445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9Y32_RS19450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9Y32_RS19460	COG2521	methyltransferase
D9Y32_RS19460	COG2136	Putative SAM-dependent methyltransferase
D9Y32_RS19470	COG0129	dihydroxy-acid dehydratase activity
D9Y32_RS19475	COG1413	lyase activity
D9Y32_RS19480	COG1418	mRNA catabolic process
D9Y32_RS19485	COG0386	Belongs to the glutathione peroxidase family
D9Y32_RS19490	COG2759	Belongs to the formate--tetrahydrofolate ligase family
D9Y32_RS19495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D9Y32_RS19500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9Y32_RS19510	COG1278	Cold shock
D9Y32_RS19530	COG0328	RNA-DNA hybrid ribonuclease activity
D9Y32_RS19535	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9Y32_RS19540	COG0328	RNA-DNA hybrid ribonuclease activity
D9Y32_RS19550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9Y32_RS19560	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9Y32_RS19575	COG3424	synthase
D9Y32_RS19580	COG0456	acetyltransferase
D9Y32_RS19585	COG2233	PERMEase
D9Y32_RS19590	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9Y32_RS19595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9Y32_RS19600	COG1199	ATP-dependent helicase activity
D9Y32_RS19610	COG0116	Belongs to the methyltransferase superfamily
D9Y32_RS19620	COG3599	regulation of cell shape
D9Y32_RS19625	COG4474	Belongs to the UPF0398 family
D9Y32_RS19635	COG3359	exonuclease
D9Y32_RS19640	COG1111	helicase
D9Y32_RS19640	COG1205	dead DEAH box helicase
D9Y32_RS19645	COG2190	(PTS) system
D9Y32_RS19650	COG0071	Belongs to the small heat shock protein (HSP20) family
D9Y32_RS19685	COG3331	DNA recombination
D9Y32_RS19690	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9Y32_RS19690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9Y32_RS19700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9Y32_RS19705	COG3935	DnaD domain protein
D9Y32_RS19710	COG0017	Asparaginyl-tRNA synthetase
D9Y32_RS19715	COG0436	Aminotransferase
D9Y32_RS19720	COG5353	protein conserved in bacteria
D9Y32_RS19730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9Y32_RS19730	COG1199	ATP-dependent helicase activity
D9Y32_RS19735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9Y32_RS19740	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9Y32_RS19745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D9Y32_RS19760	COG0617	tRNA 3'-terminal CCA addition
D9Y32_RS19765	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS19770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9Y32_RS19775	COG1803	Methylglyoxal synthase
D9Y32_RS19780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9Y32_RS19785	COG1694	Mazg nucleotide pyrophosphohydrolase
D9Y32_RS19790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS19800	COG4347	Protein of unknown function (DUF1405)
D9Y32_RS19805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9Y32_RS19805	COG2010	Cytochrome c
D9Y32_RS19810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9Y32_RS19815	COG0723	plastoquinol--plastocyanin reductase activity
D9Y32_RS19825	COG5582	Belongs to the UPF0302 family
D9Y32_RS19830	COG0457	Tetratricopeptide repeat
D9Y32_RS19835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9Y32_RS19840	COG0287	Prephenate dehydrogenase
D9Y32_RS19845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9Y32_RS19855	COG0133	tryptophan synthase activity
D9Y32_RS19860	COG0135	phosphoribosylanthranilate isomerase activity
D9Y32_RS19865	COG0134	indole-3-glycerol-phosphate synthase activity
D9Y32_RS19870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9Y32_RS19875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9Y32_RS19880	COG4401	Chorismate mutase type I
D9Y32_RS19885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9Y32_RS19890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9Y32_RS19895	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9Y32_RS19900	COG0105	UTP biosynthetic process
D9Y32_RS19905	COG0142	geranyltranstransferase activity
D9Y32_RS19910	COG2226	methyltransferase
D9Y32_RS19915	COG0142	geranyltranstransferase activity
D9Y32_RS19930	COG0776	regulation of translation
D9Y32_RS19935	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9Y32_RS19955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D9Y32_RS19960	COG1160	GTP binding
D9Y32_RS19985	COG1304	FMN binding
D9Y32_RS19990	COG0539	negative regulation of cytoplasmic translation
D9Y32_RS19995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9Y32_RS20000	COG2959	enzyme of heme biosynthesis
D9Y32_RS20005	COG3409	Peptidoglycan-binding domain 1 protein
D9Y32_RS20005	COG3773	Cell wall hydrolase
D9Y32_RS20010	COG2339	peptidase activity
D9Y32_RS20020	COG0492	ferredoxin-NADP+ reductase activity
D9Y32_RS20025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9Y32_RS20030	COG4862	establishment of competence for transformation
D9Y32_RS20035	COG1408	metallophosphoesterase
D9Y32_RS20045	COG1388	LysM domain
D9Y32_RS20050	COG1266	CAAX protease self-immunity
D9Y32_RS20055	COG0514	ATP-dependent DNA helicase (RecQ)
D9Y32_RS20060	COG4955	Helix-turn-helix domain
D9Y32_RS20065	COG1141	Ferredoxin
D9Y32_RS20070	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9Y32_RS20075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9Y32_RS20080	COG0739	heme binding
D9Y32_RS20090	COG1595	DNA-templated transcription, initiation
D9Y32_RS20095	COG1316	TRANSCRIPTIONal
D9Y32_RS20110	COG5002	protein histidine kinase activity
D9Y32_RS20115	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS20120	COG5002	protein histidine kinase activity
D9Y32_RS20125	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS20130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9Y32_RS20135	COG1333	cytochrome c biogenesis protein
D9Y32_RS20140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS20145	COG1187	pseudouridine synthase activity
D9Y32_RS20150	COG0700	Nucleoside recognition
D9Y32_RS20155	COG2715	membrane protein required for spore maturation
D9Y32_RS20160	COG1686	Belongs to the peptidase S11 family
D9Y32_RS20170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9Y32_RS20175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9Y32_RS20185	COG1547	Domain of unknown function (DUF309)
D9Y32_RS20190	COG0456	acetyltransferase
D9Y32_RS20195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9Y32_RS20200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9Y32_RS20200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9Y32_RS20205	COG0307	riboflavin synthase, alpha
D9Y32_RS20210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9Y32_RS20210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9Y32_RS20235	COG0457	Tetratricopeptide repeat
D9Y32_RS20240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9Y32_RS20245	COG4086	secreted protein
D9Y32_RS20250	COG4195	phage-related replication protein
D9Y32_RS20255	COG0019	diaminopimelate decarboxylase activity
D9Y32_RS20265	COG0697	spore germination
D9Y32_RS20280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9Y32_RS20315	COG1686	Belongs to the peptidase S11 family
D9Y32_RS20320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D9Y32_RS20325	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9Y32_RS20330	COG4974	Belongs to the 'phage' integrase family
D9Y32_RS20340	COG0735	belongs to the Fur family
D9Y32_RS20345	COG1300	Membrane
D9Y32_RS20350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS20360	COG1953	Uracil, thiamine, allantoin
D9Y32_RS20370	COG2153	protein acetylation
D9Y32_RS20375	COG1379	DNA repair
D9Y32_RS20380	COG0494	nUDIX hydrolase
D9Y32_RS20390	COG1309	transcriptional regulator
D9Y32_RS20400	COG0667	Aldo Keto reductase
D9Y32_RS20410	COG1073	alpha beta
D9Y32_RS20420	COG4918	Iron-sulphur cluster biosynthesis
D9Y32_RS20430	COG0456	acetyltransferase
D9Y32_RS20430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9Y32_RS20435	COG2329	Antibiotic biosynthesis monooxygenase
D9Y32_RS20445	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D9Y32_RS20455	COG0747	negative chemotaxis
D9Y32_RS20460	COG0601	transmembrane transport
D9Y32_RS20470	COG0444	Belongs to the ABC transporter superfamily
D9Y32_RS20480	COG0534	Mate efflux family protein
D9Y32_RS20495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9Y32_RS20505	COG2211	Major facilitator Superfamily
D9Y32_RS20510	COG0346	lactoylglutathione lyase activity
D9Y32_RS20515	COG1072	(Pantothenic acid kinase))
D9Y32_RS20530	COG1131	(ABC) transporter
D9Y32_RS20550	COG4195	phage-related replication protein
D9Y32_RS20560	COG0300	oxidoreductase activity
D9Y32_RS20565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS20570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9Y32_RS20575	COG4187	Peptidase family M20/M25/M40
D9Y32_RS20580	COG1902	pentaerythritol trinitrate reductase activity
D9Y32_RS20585	COG0596	Alpha beta hydrolase
D9Y32_RS20590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9Y32_RS20595	COG1234	tRNA 3'-trailer cleavage
D9Y32_RS20600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9Y32_RS20615	COG2358	TRAP transporter, solute receptor (TAXI family
D9Y32_RS20620	COG2188	Transcriptional regulator
D9Y32_RS20625	COG2723	6-phospho-beta-galactosidase activity
D9Y32_RS20630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS20635	COG1447	Phosphotransferase system cellobiose-specific component IIA
D9Y32_RS20640	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D9Y32_RS20645	COG1785	Belongs to the alkaline phosphatase family
D9Y32_RS20650	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS20655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9Y32_RS20660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9Y32_RS20670	COG0706	membrane insertase activity
D9Y32_RS20675	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9Y32_RS20680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9Y32_RS20685	COG4129	membrane
D9Y32_RS20690	COG1126	abc transporter atp-binding protein
D9Y32_RS20695	COG0765	amino acid transport
D9Y32_RS20700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9Y32_RS20710	COG1597	lipid kinase activity
D9Y32_RS20715	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9Y32_RS20720	COG0022	dehydrogenase e1 component
D9Y32_RS20725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9Y32_RS20730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9Y32_RS20735	COG3426	butyrate kinase activity
D9Y32_RS20745	COG0280	phosphate acetyltransferase
D9Y32_RS20750	COG3829	transcription factor binding
D9Y32_RS20750	COG3290	protein histidine kinase activity
D9Y32_RS20760	COG0584	glycerophosphoryl diester phosphodiesterase
D9Y32_RS20765	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9Y32_RS20780	COG1045	serine acetyltransferase
D9Y32_RS20790	COG0745	RESPONSE REGULATOR receiver
D9Y32_RS20795	COG0750	zinc metalloprotease
D9Y32_RS20800	COG0497	DNA recombination
D9Y32_RS20805	COG1438	arginine binding
D9Y32_RS20810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9Y32_RS20815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9Y32_RS20820	COG0142	geranyltranstransferase activity
D9Y32_RS20825	COG1722	exodeoxyribonuclease VII activity
D9Y32_RS20830	COG1570	exodeoxyribonuclease VII activity
D9Y32_RS20835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9Y32_RS20840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9Y32_RS20845	COG1302	Protein conserved in bacteria
D9Y32_RS20850	COG0439	Biotin carboxylase
D9Y32_RS20855	COG0511	ligase activity, forming carbon-carbon bonds
D9Y32_RS20895	COG3854	ATPases associated with a variety of cellular activities
D9Y32_RS20905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9Y32_RS20915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D9Y32_RS20925	COG3872	metal-dependent enzyme
D9Y32_RS20935	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9Y32_RS20940	COG1321	iron dependent repressor
D9Y32_RS20945	COG0095	Lipoate-protein ligase
D9Y32_RS20950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9Y32_RS20955	COG2113	Glycine betaine
D9Y32_RS20960	COG4176	ABC-type proline glycine betaine transport system permease component
D9Y32_RS20965	COG0517	IMP dehydrogenase activity
D9Y32_RS20965	COG4175	Glycine betaine
D9Y32_RS20970	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9Y32_RS20975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9Y32_RS20985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9Y32_RS21010	COG0681	Belongs to the peptidase S26 family
D9Y32_RS21035	COG4940	Competence protein ComGF
D9Y32_RS21045	COG4970	Tfp pilus assembly protein FimT
D9Y32_RS21050	COG4537	Required for transformation and DNA binding
D9Y32_RS21055	COG1459	type II secretion system
D9Y32_RS21060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9Y32_RS21065	COG1366	Belongs to the anti-sigma-factor antagonist family
D9Y32_RS21075	COG1393	Belongs to the ArsC family
D9Y32_RS21085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS21095	COG0011	TIGRFAM Protein of
D9Y32_RS21105	COG2866	Carboxypeptidase
D9Y32_RS21110	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9Y32_RS21115	COG1368	sulfuric ester hydrolase activity
D9Y32_RS21120	COG1940	carbohydrate kinase activity
D9Y32_RS21130	COG0697	spore germination
D9Y32_RS21135	COG0457	Tetratricopeptide repeat
D9Y32_RS21135	COG0705	Rhomboid family
D9Y32_RS21140	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9Y32_RS21145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9Y32_RS21150	COG0438	transferase activity, transferring glycosyl groups
D9Y32_RS21165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9Y32_RS21170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9Y32_RS21175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9Y32_RS21180	COG0581	inorganic phosphate transmembrane transporter activity
D9Y32_RS21185	COG0573	inorganic phosphate transmembrane transporter activity
D9Y32_RS21190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9Y32_RS21195	COG0768	penicillin binding
D9Y32_RS21200	COG0477	Major facilitator Superfamily
D9Y32_RS21205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9Y32_RS21210	COG2839	Protein conserved in bacteria
D9Y32_RS21215	COG5521	maltodextrose utilization protein MalA
D9Y32_RS21220	COG1388	LysM domain
D9Y32_RS21225	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D9Y32_RS21230	COG4709	membrane
D9Y32_RS21235	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9Y32_RS21240	COG0735	belongs to the Fur family
D9Y32_RS21245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9Y32_RS21250	COG1121	(ABC) transporter
D9Y32_RS21255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS21265	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9Y32_RS21270	COG0513	Belongs to the DEAD box helicase family
D9Y32_RS21280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9Y32_RS21285	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9Y32_RS21290	COG2384	SAM-dependent methyltransferase
D9Y32_RS21305	COG2323	membrane
D9Y32_RS21310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9Y32_RS21315	COG2323	membrane
D9Y32_RS21335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9Y32_RS21360	COG3546	catalase activity
D9Y32_RS21405	COG1252	NADH dehydrogenase
D9Y32_RS21420	COG0166	Belongs to the GPI family
D9Y32_RS21430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9Y32_RS21435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9Y32_RS21440	COG1024	Enoyl-CoA hydratase
D9Y32_RS21445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9Y32_RS21450	COG0511	ligase activity, forming carbon-carbon bonds
D9Y32_RS21455	COG0439	Biotin carboxylase
D9Y32_RS21460	COG0318	PFAM AMP-dependent synthetase and ligase
D9Y32_RS21465	COG1960	acyl-CoA dehydrogenase activity
D9Y32_RS21470	COG2249	NAD(P)H dehydrogenase (quinone) activity
D9Y32_RS21480	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9Y32_RS21485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9Y32_RS21495	COG2323	membrane
D9Y32_RS21505	COG0306	phosphate transporter
D9Y32_RS21510	COG0175	sulfate reduction
D9Y32_RS21515	COG1809	phosphosulfolactate synthase activity
D9Y32_RS21520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9Y32_RS21525	COG4948	Mandelate Racemase Muconate Lactonizing
D9Y32_RS21530	COG2814	Major facilitator Superfamily
D9Y32_RS21535	COG0463	Glycosyl transferase, family 2
D9Y32_RS21550	COG0493	'glutamate synthase
D9Y32_RS21555	COG0070	glutamate synthase
D9Y32_RS21555	COG0069	glutamate synthase activity
D9Y32_RS21555	COG0067	glutamate synthase
D9Y32_RS21560	COG0583	DNA-binding transcription factor activity
D9Y32_RS21580	COG1846	Transcriptional regulator
D9Y32_RS21590	COG1132	(ABC) transporter
D9Y32_RS21600	COG0300	oxidoreductase activity
D9Y32_RS21605	COG0574	Belongs to the PEP-utilizing enzyme family
D9Y32_RS21605	COG3848	Pyruvate phosphate dikinase
D9Y32_RS21610	COG0477	Major facilitator Superfamily
D9Y32_RS21615	COG0243	molybdopterin cofactor binding
D9Y32_RS21620	COG1846	Transcriptional regulator
D9Y32_RS21630	COG0531	amino acid
D9Y32_RS21645	COG0531	amino acid
D9Y32_RS21655	COG0488	(ABC) transporter
D9Y32_RS21660	COG0840	transmembrane signaling receptor activity
D9Y32_RS21665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9Y32_RS21670	COG1404	Belongs to the peptidase S8 family
D9Y32_RS21680	COG1309	transcriptional regulator
D9Y32_RS21685	COG1846	Transcriptional regulator
D9Y32_RS21715	COG1309	transcriptional regulator
D9Y32_RS21720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS21725	COG3708	Transcriptional regulator
D9Y32_RS21735	COG2378	regulation of single-species biofilm formation
D9Y32_RS21745	COG0640	Transcriptional regulator
D9Y32_RS21750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9Y32_RS21760	COG0531	amino acid
D9Y32_RS21765	COG0741	lytic transglycosylase activity
D9Y32_RS21770	COG1086	Polysaccharide biosynthesis protein
D9Y32_RS21790	COG2322	membrane
D9Y32_RS21805	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS21810	COG3584	3D domain protein
D9Y32_RS21810	COG1388	LysM domain
D9Y32_RS21815	COG0514	ATP-dependent DNA helicase (RecQ)
D9Y32_RS21835	COG2315	Protein conserved in bacteria
D9Y32_RS21875	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
D9Y32_RS21925	COG0402	S-adenosylhomocysteine deaminase activity
D9Y32_RS21940	COG2267	carboxylic ester hydrolase activity
D9Y32_RS21955	COG1280	lysine exporter protein (LysE YggA)
D9Y32_RS21960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9Y32_RS21970	COG0574	Belongs to the PEP-utilizing enzyme family
D9Y32_RS21970	COG3848	Pyruvate phosphate dikinase
D9Y32_RS21975	COG1309	transcriptional regulator
D9Y32_RS21990	COG2318	DinB family
D9Y32_RS21995	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D9Y32_RS22000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9Y32_RS22015	COG1012	belongs to the aldehyde dehydrogenase family
D9Y32_RS22020	COG2814	Major facilitator Superfamily
D9Y32_RS22035	COG1657	PFAM Prenyltransferase squalene oxidase
D9Y32_RS22040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D9Y32_RS22050	COG0733	neurotransmitter:sodium symporter activity
D9Y32_RS22055	COG0385	Bile acid
D9Y32_RS22060	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9Y32_RS22065	COG0567	Dehydrogenase, E1 component
D9Y32_RS22070	COG4548	von Willebrand factor, type A
D9Y32_RS22075	COG0714	Associated with various cellular activities
D9Y32_RS22080	COG2032	superoxide dismutase activity
D9Y32_RS22085	COG1388	LysM domain
D9Y32_RS22085	COG0791	NLP P60 protein
D9Y32_RS22095	COG0534	Mate efflux family protein
D9Y32_RS22100	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9Y32_RS22105	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9Y32_RS22125	COG4305	rare lipoprotein A
D9Y32_RS22135	COG1028	Short-chain dehydrogenase reductase Sdr
D9Y32_RS22140	COG1733	regulation of RNA biosynthetic process
D9Y32_RS22145	COG0778	Nitroreductase
D9Y32_RS22150	COG0400	carboxylic ester hydrolase activity
D9Y32_RS22160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9Y32_RS22165	COG0793	Belongs to the peptidase S41A family
D9Y32_RS22165	COG3409	Peptidoglycan-binding domain 1 protein
D9Y32_RS22170	COG2226	methyltransferase
D9Y32_RS22180	COG1876	peptidase activity
D9Y32_RS22185	COG0813	purine-nucleoside phosphorylase activity
D9Y32_RS22190	COG0701	Predicted permease
D9Y32_RS22210	COG0671	phosphoesterase, PA-phosphatase related
D9Y32_RS22225	COG4479	Belongs to the UPF0346 family
D9Y32_RS22240	COG3331	DNA recombination
D9Y32_RS22250	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D9Y32_RS22275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9Y32_RS22310	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9Y32_RS22325	COG0756	dUTP diphosphatase activity
D9Y32_RS22335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9Y32_RS22340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9Y32_RS22345	COG0270	DNA (cytosine-5-)-methyltransferase activity
D9Y32_RS22355	COG1372	Participates in initiation and elongation during chromosome replication
D9Y32_RS22355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9Y32_RS22365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9Y32_RS22370	COG1780	Probably involved in ribonucleotide reductase function
D9Y32_RS22435	COG3584	3D domain protein
D9Y32_RS22440	COG0587	DNA-directed DNA polymerase activity
D9Y32_RS22450	COG0587	DNA-directed DNA polymerase activity
D9Y32_RS22455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9Y32_RS22460	COG0358	DNA primase activity
D9Y32_RS22465	COG0305	Participates in initiation and elongation during chromosome replication
D9Y32_RS22475	COG2887	Belongs to the helicase family. UvrD subfamily
D9Y32_RS22535	COG1793	dna ligase
D9Y32_RS22575	COG4474	Belongs to the UPF0398 family
D9Y32_RS22590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9Y32_RS22620	COG0582	viral genome integration into host DNA
D9Y32_RS22650	COG1404	Belongs to the peptidase S8 family
D9Y32_RS22740	COG3655	Transcriptional regulator
D9Y32_RS22850	COG0776	regulation of translation