locus-tag	class	description
D9783_RS00010	COG1725	Transcriptional regulator
D9783_RS00015	COG0281	malic enzyme
D9783_RS00020	COG0587	DNA-directed DNA polymerase activity
D9783_RS00045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D9783_RS00055	COG4109	DRTGG domain
D9783_RS00080	COG0589	response to stress
D9783_RS00090	COG2217	Heavy metal translocating P-type atpase
D9783_RS00095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D9783_RS00100	COG0827	DNA restriction-modification system
D9783_RS00105	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
D9783_RS00110	COG3874	Sporulation protein YtfJ
D9783_RS00120	COG1714	RDD family
D9783_RS00125	COG0616	signal peptide processing
D9783_RS00130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D9783_RS00135	COG2962	Rard protein
D9783_RS00140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9783_RS00145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9783_RS00150	COG0534	Mate efflux family protein
D9783_RS00160	COG0301	tRNA thio-modification
D9783_RS00165	COG1104	cysteine desulfurase activity
D9783_RS00170	COG1114	Component of the transport system for branched-chain amino acids
D9783_RS00180	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
D9783_RS00185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9783_RS00190	COG1309	transcriptional regulator
D9783_RS00195	COG1956	GAF domain-containing protein
D9783_RS00210	COG0626	cystathionine gamma-synthase activity
D9783_RS00215	COG2203	Gaf domain
D9783_RS00215	COG2199	diguanylate cyclase activity
D9783_RS00225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
D9783_RS00230	COG0517	IMP dehydrogenase activity
D9783_RS00240	COG1132	(ABC) transporter
D9783_RS00255	COG0517	IMP dehydrogenase activity
D9783_RS00285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9783_RS00290	COG0454	-acetyltransferase
D9783_RS00295	COG0517	IMP dehydrogenase activity
D9783_RS00300	COG0123	including yeast histone deacetylase and acetoin utilization protein
D9783_RS00320	COG1605	Chorismate mutase
D9783_RS00320	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D9783_RS00330	COG3118	belongs to the thioredoxin family
D9783_RS00335	COG4980	gas vesicle protein
D9783_RS00345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D9783_RS00355	COG1674	ftsk spoiiie
D9783_RS00360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9783_RS00365	COG4848	Belongs to the UPF0354 family
D9783_RS00370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS00390	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D9783_RS00395	COG1363	Peptidase, m42
D9783_RS00410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS00415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D9783_RS00425	COG0510	thiamine kinase activity
D9783_RS00430	COG1523	belongs to the glycosyl hydrolase 13 family
D9783_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9783_RS00455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9783_RS00460	COG1349	DNA-binding transcription factor activity
D9783_RS00465	COG1187	pseudouridine synthase activity
D9783_RS00470	COG2244	polysaccharide biosynthetic process
D9783_RS00475	COG2081	HI0933 family
D9783_RS00485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9783_RS00490	COG0495	leucyl-tRNA aminoacylation
D9783_RS00500	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS00505	COG2814	Major facilitator Superfamily
D9783_RS00525	COG1242	4 iron, 4 sulfur cluster binding
D9783_RS00530	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D9783_RS00540	COG2267	carboxylic ester hydrolase activity
D9783_RS00545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D9783_RS00550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D9783_RS00570	COG1506	peptidase
D9783_RS00575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9783_RS00580	COG1116	anion transmembrane transporter activity
D9783_RS00585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9783_RS00590	COG0494	nUDIX hydrolase
D9783_RS00605	COG4824	toxin secretion phage lysis holin
D9783_RS00620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D9783_RS00625	COG1271	oxidase subunit
D9783_RS00630	COG1294	oxidase, subunit
D9783_RS00655	COG5278	phosphoserine phosphatase activity
D9783_RS00655	COG0840	transmembrane signaling receptor activity
D9783_RS00670	COG2199	diguanylate cyclase activity
D9783_RS00680	COG2207	Transcriptional regulator
D9783_RS00695	COG2207	Transcriptional regulator
D9783_RS00695	COG3708	Transcriptional regulator
D9783_RS00700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9783_RS00705	COG0456	acetyltransferase
D9783_RS00705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9783_RS00710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9783_RS00765	COG0135	phosphoribosylanthranilate isomerase activity
D9783_RS00805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9783_RS00810	COG2814	Major facilitator Superfamily
D9783_RS00815	COG4948	Mandelate Racemase Muconate Lactonizing
D9783_RS00820	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS00825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D9783_RS00830	COG0596	Alpha beta hydrolase
D9783_RS00835	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D9783_RS00840	COG1169	isochorismate synthase
D9783_RS00845	COG1575	Belongs to the MenA family. Type 1 subfamily
D9783_RS00855	COG0058	SHG alpha-glucan phosphorylase activity
D9783_RS00860	COG0297	glycogen (starch) synthase activity
D9783_RS00865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D9783_RS01025	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS01040	COG0431	NADPH-dependent FMN reductase
D9783_RS01050	COG3069	C4-dicarboxylate transmembrane transporter activity
D9783_RS01055	COG1309	transcriptional regulator
D9783_RS01060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS01065	COG2706	6-phosphogluconolactonase activity
D9783_RS01070	COG3300	MHYT domain
D9783_RS01070	COG5001	Diguanylate cyclase
D9783_RS01090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS01095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9783_RS01110	COG1979	alcohol dehydrogenase
D9783_RS01115	COG2155	Conserved Protein
D9783_RS01120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9783_RS01125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9783_RS01130	COG1012	belongs to the aldehyde dehydrogenase family
D9783_RS01135	COG3829	transcription factor binding
D9783_RS01140	COG1098	S1 RNA binding domain
D9783_RS01150	COG1595	DNA-templated transcription, initiation
D9783_RS01160	COG2267	carboxylic ester hydrolase activity
D9783_RS01165	COG0288	reversible hydration of carbon dioxide
D9783_RS01175	COG5609	conserved protein (DUF2294)
D9783_RS01185	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D9783_RS01190	COG2032	superoxide dismutase activity
D9783_RS01200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9783_RS01210	COG5018	Exonuclease
D9783_RS01215	COG2814	Major facilitator Superfamily
D9783_RS01220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9783_RS01235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D9783_RS01235	COG2111	Na H antiporter
D9783_RS01240	COG2111	Na H antiporter
D9783_RS01245	COG1006	Multisubunit Na H antiporter MnhC subunit
D9783_RS01250	COG0651	ATP synthesis coupled electron transport
D9783_RS01255	COG1863	multisubunit Na H antiporter MnhE subunit
D9783_RS01260	COG2212	antiporter activity
D9783_RS01265	COG1320	monovalent cation:proton antiporter activity
D9783_RS01270	COG2050	protein possibly involved in aromatic compounds catabolism
D9783_RS01275	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9783_RS01295	COG2056	Na+-H+ antiporter family
D9783_RS01300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D9783_RS01305	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
D9783_RS01315	COG3584	3D domain protein
D9783_RS01330	COG1252	NADH dehydrogenase
D9783_RS01335	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS01340	COG0316	Belongs to the HesB IscA family
D9783_RS01355	COG1252	NADH dehydrogenase
D9783_RS01365	COG4837	Protein of unknown function (DUF1462)
D9783_RS01370	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D9783_RS01375	COG1309	transcriptional regulator
D9783_RS01380	COG2076	Multidrug Resistance protein
D9783_RS01385	COG2076	Multidrug Resistance protein
D9783_RS01395	COG1595	DNA-templated transcription, initiation
D9783_RS01405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9783_RS01410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D9783_RS01415	COG0647	UMP catabolic process
D9783_RS01420	COG2445	Protein of unknown function DUF86
D9783_RS01435	COG4470	Protein conserved in bacteria
D9783_RS01445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D9783_RS01450	COG0739	heme binding
D9783_RS01460	COG0733	neurotransmitter:sodium symporter activity
D9783_RS01465	COG1757	Na H antiporter
D9783_RS01480	COG3377	Domain of unknown function (DUF1805)
D9783_RS01485	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS01490	COG0730	response to heat
D9783_RS01495	COG1801	Protein of unknown function DUF72
D9783_RS01505	COG0719	Fe-S assembly protein
D9783_RS01510	COG0822	iron-sulfur transferase activity
D9783_RS01515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D9783_RS01520	COG0719	Fe-S assembly protein
D9783_RS01525	COG0396	ATPase activity
D9783_RS01530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D9783_RS01535	COG1464	Belongs to the NlpA lipoprotein family
D9783_RS01540	COG2011	ABC-type metal ion transport system permease component
D9783_RS01545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9783_RS01555	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS01560	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
D9783_RS01570	COG0509	glycine decarboxylation via glycine cleavage system
D9783_RS01575	COG1393	Belongs to the ArsC family
D9783_RS01580	COG1960	acyl-CoA dehydrogenase activity
D9783_RS01585	COG0183	Belongs to the thiolase family
D9783_RS01590	COG1024	Enoyl-CoA hydratase
D9783_RS01590	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9783_RS01610	COG5577	PFAM Coat F domain
D9783_RS01625	COG1120	ATPase activity
D9783_RS01630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS01635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS01640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9783_RS01650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS01660	COG2323	membrane
D9783_RS01680	COG5002	protein histidine kinase activity
D9783_RS01680	COG3850	Histidine kinase
D9783_RS01685	COG0745	RESPONSE REGULATOR receiver
D9783_RS01695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9783_RS01700	COG0477	Major facilitator Superfamily
D9783_RS01710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9783_RS01720	COG0400	carboxylic ester hydrolase activity
D9783_RS01725	COG0346	lactoylglutathione lyase activity
D9783_RS01730	COG2208	phosphoserine phosphatase activity
D9783_RS01745	COG1131	(ABC) transporter
D9783_RS01760	COG1846	Transcriptional regulator
D9783_RS01765	COG1764	response to oxidative stress
D9783_RS01775	COG0586	Pfam SNARE associated Golgi protein
D9783_RS01800	COG0435	Glutathione S-transferase
D9783_RS01840	COG0557	exoribonuclease II activity
D9783_RS01845	COG1647	Serine aminopeptidase, S33
D9783_RS01850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9783_RS01860	COG0148	phosphopyruvate hydratase activity
D9783_RS01865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D9783_RS01895	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
D9783_RS01920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9783_RS01930	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D9783_RS01935	COG1660	Displays ATPase and GTPase activities
D9783_RS01940	COG1051	belongs to the nudix hydrolase family
D9783_RS01945	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS01950	COG0457	Tetratricopeptide repeat
D9783_RS01955	COG0140	phosphoribosyl-ATP diphosphatase activity
D9783_RS01955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D9783_RS01960	COG0107	imidazoleglycerol-phosphate synthase activity
D9783_RS01965	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D9783_RS01970	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D9783_RS01975	COG0131	Imidazoleglycerol-phosphate dehydratase
D9783_RS01980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D9783_RS01985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D9783_RS01990	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
D9783_RS02000	COG0110	maltose O-acetyltransferase activity
D9783_RS02005	COG0546	phosphoglycolate phosphatase activity
D9783_RS02010	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
D9783_RS02020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D9783_RS02025	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
D9783_RS02030	COG1950	PFAM Membrane protein of
D9783_RS02040	COG3595	metallopeptidase activity
D9783_RS02050	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D9783_RS02055	COG0556	nucleotide-excision repair
D9783_RS02060	COG4897	Protein conserved in bacteria
D9783_RS02070	COG0596	Alpha beta hydrolase
D9783_RS02080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D9783_RS02105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9783_RS02110	COG0569	domain protein
D9783_RS02130	COG1131	(ABC) transporter
D9783_RS02150	COG1595	DNA-templated transcription, initiation
D9783_RS02160	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9783_RS02165	COG0793	Belongs to the peptidase S41A family
D9783_RS02165	COG3409	Peptidoglycan-binding domain 1 protein
D9783_RS02170	COG0626	cystathionine gamma-synthase activity
D9783_RS02175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS02185	COG0697	spore germination
D9783_RS02205	COG0739	heme binding
D9783_RS02210	COG2177	Part of the ABC transporter FtsEX involved in
D9783_RS02215	COG2884	Cell division ATP-binding protein ftsE
D9783_RS02225	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS02245	COG0653	protein targeting
D9783_RS02250	COG1070	Carbohydrate kinase
D9783_RS02260	COG3012	SEC-C Motif Domain Protein
D9783_RS02260	COG1405	negative regulation of cell septum assembly
D9783_RS02275	COG2059	Chromate
D9783_RS02280	COG2059	Chromate
D9783_RS02290	COG4608	Belongs to the ABC transporter superfamily
D9783_RS02295	COG0444	Belongs to the ABC transporter superfamily
D9783_RS02300	COG0747	negative chemotaxis
D9783_RS02305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9783_RS02315	COG1522	sequence-specific DNA binding
D9783_RS02335	COG1516	flagellar protein fliS
D9783_RS02340	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D9783_RS02345	COG1334	flagellar protein FlaG
D9783_RS02355	COG0463	Glycosyl transferase, family 2
D9783_RS02355	COG0457	Tetratricopeptide repeat
D9783_RS02360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9783_RS02365	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
D9783_RS02370	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
D9783_RS02380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D9783_RS02385	COG4786	Flagellar basal body rod
D9783_RS02385	COG1256	bacterial-type flagellum assembly
D9783_RS02395	COG2747	anti-sigma28 factor FlgM
D9783_RS02405	COG1040	competence protein
D9783_RS02410	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D9783_RS02415	COG1307	EDD domain protein, DegV family
D9783_RS02425	COG1263	PTS System
D9783_RS02425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9783_RS02430	COG0366	Alpha amylase catalytic
D9783_RS02435	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9783_RS02435	COG2199	diguanylate cyclase activity
D9783_RS02445	COG2188	Transcriptional regulator
D9783_RS02450	COG2197	response regulator
D9783_RS02455	COG4585	Histidine kinase
D9783_RS02460	COG1739	Uncharacterized protein family UPF0029
D9783_RS02465	COG1316	TRANSCRIPTIONal
D9783_RS02470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9783_RS02475	COG0653	protein targeting
D9783_RS02490	COG3706	GGDEF domain
D9783_RS02495	COG3227	Zinc metalloprotease (Elastase)
D9783_RS02525	COG2814	Major facilitator Superfamily
D9783_RS02530	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS02535	COG1408	metallophosphoesterase
D9783_RS02545	COG3858	chitin binding
D9783_RS02560	COG1404	Belongs to the peptidase S8 family
D9783_RS02575	COG0789	Transcriptional regulator
D9783_RS02595	COG0726	polysaccharide deacetylase
D9783_RS02600	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS02605	COG2356	endonuclease I
D9783_RS02610	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS02615	COG0840	transmembrane signaling receptor activity
D9783_RS02635	COG0438	transferase activity, transferring glycosyl groups
D9783_RS02660	COG0728	peptidoglycan biosynthetic process
D9783_RS02675	COG5263	repeat protein
D9783_RS02675	COG4193	domain, Protein
D9783_RS02680	COG1404	Belongs to the peptidase S8 family
D9783_RS02690	COG1388	LysM domain
D9783_RS02690	COG0791	NLP P60 protein
D9783_RS02690	COG3103	Sh3 type 3 domain protein
D9783_RS02695	COG1404	Belongs to the peptidase S8 family
D9783_RS02715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
D9783_RS02720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9783_RS02735	COG1361	Conserved repeat domain
D9783_RS02750	COG1227	inorganic diphosphatase activity
D9783_RS02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS02805	COG1454	alcohol dehydrogenase
D9783_RS02815	COG1012	belongs to the aldehyde dehydrogenase family
D9783_RS02825	COG2207	Transcriptional regulator
D9783_RS02840	COG1122	ATPase activity
D9783_RS02855	COG1361	Conserved repeat domain
D9783_RS02855	COG2911	Protein conserved in bacteria
D9783_RS02855	COG3266	domain, Protein
D9783_RS02860	COG0693	protein deglycase activity
D9783_RS02865	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS02865	COG1525	nuclease
D9783_RS02865	COG4085	toxin activity
D9783_RS02870	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D9783_RS02880	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9783_RS02885	COG3266	domain, Protein
D9783_RS02885	COG1361	Conserved repeat domain
D9783_RS02885	COG2911	Protein conserved in bacteria
D9783_RS02895	COG2340	Cysteine-rich secretory protein family
D9783_RS02920	COG5002	protein histidine kinase activity
D9783_RS02925	COG2076	Multidrug Resistance protein
D9783_RS02940	COG1970	mechanosensitive ion channel activity
D9783_RS02945	COG0842	Transport permease protein
D9783_RS02950	COG1511	domain protein
D9783_RS02950	COG0842	Transport permease protein
D9783_RS02955	COG1131	(ABC) transporter
D9783_RS02960	COG2197	response regulator
D9783_RS02965	COG4585	Histidine kinase
D9783_RS02975	COG1595	DNA-templated transcription, initiation
D9783_RS03000	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9783_RS03020	COG1595	DNA-templated transcription, initiation
D9783_RS03085	COG1404	Belongs to the peptidase S8 family
D9783_RS03090	COG3693	PFAM glycoside hydrolase, family 10
D9783_RS03120	COG1361	Conserved repeat domain
D9783_RS03130	COG1376	ErfK ybiS ycfS ynhG family protein
D9783_RS03135	COG0840	transmembrane signaling receptor activity
D9783_RS03150	COG0840	transmembrane signaling receptor activity
D9783_RS03155	COG3279	Response regulator of the LytR AlgR family
D9783_RS03180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9783_RS03215	COG3594	Acyltransferase
D9783_RS03225	COG3958	Transketolase
D9783_RS03230	COG3959	Transketolase, thiamine diphosphate binding domain
D9783_RS03235	COG3037	sugar-specific permease SgaT UlaA
D9783_RS03245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9783_RS03255	COG0517	IMP dehydrogenase activity
D9783_RS03275	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9783_RS03290	COG0517	IMP dehydrogenase activity
D9783_RS03345	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9783_RS03345	COG3443	Belongs to the bacterial solute-binding protein 9 family
D9783_RS03365	COG0772	Belongs to the SEDS family
D9783_RS03395	COG1361	Conserved repeat domain
D9783_RS03405	COG0653	protein targeting
D9783_RS03420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D9783_RS03475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9783_RS03485	COG0728	peptidoglycan biosynthetic process
D9783_RS03495	COG1215	transferase activity, transferring glycosyl groups
D9783_RS03505	COG0438	transferase activity, transferring glycosyl groups
D9783_RS03520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9783_RS03525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9783_RS03540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9783_RS03550	COG4464	protein tyrosine phosphatase activity
D9783_RS03555	COG0489	protein tyrosine kinase activity
D9783_RS03560	COG3944	biosynthesis protein
D9783_RS03600	COG1785	Belongs to the alkaline phosphatase family
D9783_RS03605	COG4715	Zinc finger, swim domain protein
D9783_RS03610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9783_RS03620	COG0629	single-stranded DNA binding
D9783_RS03675	COG4786	Flagellar basal body rod
D9783_RS03680	COG4786	Flagellar basal body rod
D9783_RS03685	COG1077	Cell shape determining protein MreB Mrl
D9783_RS03690	COG1609	Transcriptional regulator
D9783_RS03695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9783_RS03710	COG0739	heme binding
D9783_RS03720	COG2385	sporulation resulting in formation of a cellular spore
D9783_RS03730	COG4836	Membrane
D9783_RS03740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9783_RS03745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D9783_RS03750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D9783_RS03755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9783_RS03760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
D9783_RS03765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D9783_RS03770	COG0356	it plays a direct role in the translocation of protons across the membrane
D9783_RS03785	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
D9783_RS03790	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D9783_RS03795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D9783_RS03815	COG0698	ribose 5-phosphate isomerase
D9783_RS03825	COG0840	transmembrane signaling receptor activity
D9783_RS03850	COG1132	(ABC) transporter
D9783_RS03885	COG1132	(ABC) transporter
D9783_RS03910	COG1215	transferase activity, transferring glycosyl groups
D9783_RS03915	COG0438	transferase activity, transferring glycosyl groups
D9783_RS03920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D9783_RS03945	COG2089	acid synthase
D9783_RS03960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D9783_RS03970	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D9783_RS03985	COG0438	transferase activity, transferring glycosyl groups
D9783_RS03990	COG1216	Glycosyl transferase, family 2
D9783_RS03995	COG1132	(ABC) transporter
D9783_RS04020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D9783_RS04030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D9783_RS04035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9783_RS04045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D9783_RS04055	COG0489	protein tyrosine kinase activity
D9783_RS04060	COG3944	biosynthesis protein
D9783_RS04065	COG1971	Probably functions as a manganese efflux pump
D9783_RS04070	COG0009	L-threonylcarbamoyladenylate synthase
D9783_RS04085	COG2890	protein-(glutamine-N5) methyltransferase activity
D9783_RS04090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D9783_RS04105	COG1435	thymidine kinase activity
D9783_RS04115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D9783_RS04120	COG1494	fructose-1,6-bisphosphatase
D9783_RS04125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D9783_RS04130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D9783_RS04135	COG0191	fructose-bisphosphate aldolase activity
D9783_RS04140	COG2204	response regulator
D9783_RS04145	COG4821	SIS domain
D9783_RS04155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9783_RS04160	COG0504	CTP synthase activity
D9783_RS04175	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9783_RS04175	COG1703	isobutyryl-CoA mutase activity
D9783_RS04175	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9783_RS04185	COG1960	acyl-CoA dehydrogenase activity
D9783_RS04190	COG1960	acyl-CoA dehydrogenase activity
D9783_RS04195	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9783_RS04200	COG0183	Belongs to the thiolase family
D9783_RS04205	COG0247	lactate metabolic process
D9783_RS04205	COG2181	nitrate reductase activity
D9783_RS04210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9783_RS04230	COG0018	arginyl-trna synthetase
D9783_RS04240	COG0010	Belongs to the arginase family
D9783_RS04250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9783_RS04260	COG1994	Peptidase M50
D9783_RS04275	COG3465	dGTPase activity
D9783_RS04280	COG1078	dGTPase activity
D9783_RS04285	COG4844	belongs to the
D9783_RS04295	COG0095	Lipoate-protein ligase
D9783_RS04315	COG0280	phosphate acetyltransferase
D9783_RS04325	COG3773	Cell wall hydrolase
D9783_RS04335	COG2363	Small membrane protein
D9783_RS04350	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D9783_RS04365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9783_RS04370	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9783_RS04410	COG0714	Associated with various cellular activities
D9783_RS04435	COG0156	8-amino-7-oxononanoate synthase activity
D9783_RS04455	COG2364	Membrane
D9783_RS04465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9783_RS04475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D9783_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9783_RS04480	COG0723	plastoquinol--plastocyanin reductase activity
D9783_RS04490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9783_RS04490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9783_RS04510	COG4176	ABC-type proline glycine betaine transport system permease component
D9783_RS04520	COG1510	regulation of RNA biosynthetic process
D9783_RS04525	COG1785	Belongs to the alkaline phosphatase family
D9783_RS04560	COG2270	Major facilitator Superfamily
D9783_RS04570	COG2207	Transcriptional regulator
D9783_RS04585	COG0789	Transcriptional regulator
D9783_RS04590	COG2176	DNA-directed DNA polymerase activity
D9783_RS04600	COG0004	ammonium transporteR
D9783_RS04605	COG5278	phosphoserine phosphatase activity
D9783_RS04605	COG0840	transmembrane signaling receptor activity
D9783_RS04610	COG1464	Belongs to the NlpA lipoprotein family
D9783_RS04620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9783_RS04625	COG2304	oxidoreductase activity
D9783_RS04630	COG0697	spore germination
D9783_RS04635	COG5278	phosphoserine phosphatase activity
D9783_RS04635	COG0840	transmembrane signaling receptor activity
D9783_RS04645	COG0463	Glycosyl transferase, family 2
D9783_RS04660	COG0254	rRNA binding
D9783_RS04665	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9783_RS04675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS04680	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS04685	COG1120	ATPase activity
D9783_RS04700	COG0395	ABC-type sugar transport system, permease component
D9783_RS04705	COG1175	transmembrane transport
D9783_RS04710	COG1653	transport
D9783_RS04720	COG3459	Glycosyltransferase 36 associated
D9783_RS04725	COG1309	transcriptional regulator
D9783_RS04730	COG2814	Major facilitator Superfamily
D9783_RS04735	COG2205	protein histidine kinase activity
D9783_RS04755	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
D9783_RS04760	COG3766	membrane
D9783_RS04770	COG1842	Phage shock protein A
D9783_RS04810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D9783_RS04820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9783_RS04825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D9783_RS04830	COG4853	Protein conserved in bacteria
D9783_RS04835	COG4863	YycH protein
D9783_RS04840	COG5002	protein histidine kinase activity
D9783_RS04845	COG0745	RESPONSE REGULATOR receiver
D9783_RS04875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D9783_RS04880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D9783_RS04885	COG0305	Participates in initiation and elongation during chromosome replication
D9783_RS04895	COG0359	binds to the 23S rRNA
D9783_RS04900	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
D9783_RS04910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
D9783_RS04915	COG0629	single-stranded DNA binding
D9783_RS04920	COG0360	Binds together with S18 to 16S ribosomal RNA
D9783_RS04930	COG0012	GTP binding
D9783_RS04935	COG4481	Protein conserved in bacteria
D9783_RS04940	COG0668	transmembrane transport
D9783_RS04955	COG1475	DNA binding
D9783_RS04960	COG1192	Involved in chromosome partitioning
D9783_RS04965	COG1475	DNA binding
D9783_RS04970	COG0357	Ribosomal RNA small subunit methyltransferase G
D9783_RS04980	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D9783_RS04985	COG1847	R3H domain protein
D9783_RS04990	COG0706	membrane insertase activity
D9783_RS04995	COG0594	ribonuclease P activity
D9783_RS05000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
D9783_RS05005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D9783_RS05010	COG0592	DNA-directed DNA polymerase activity
D9783_RS05015	COG2501	S4 domain
D9783_RS05020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D9783_RS05030	COG0187	DNA topoisomerase II activity
D9783_RS05035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9783_RS05040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9783_RS05080	COG0386	Belongs to the glutathione peroxidase family
D9783_RS05090	COG0516	GMP reductase activity
D9783_RS05090	COG0517	IMP dehydrogenase activity
D9783_RS05105	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
D9783_RS05120	COG1428	Deoxynucleoside kinase
D9783_RS05125	COG1428	Deoxynucleoside kinase
D9783_RS05130	COG3858	chitin binding
D9783_RS05130	COG1388	LysM domain
D9783_RS05135	COG1335	isochorismatase
D9783_RS05140	COG0590	tRNA wobble adenosine to inosine editing
D9783_RS05150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D9783_RS05155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D9783_RS05160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D9783_RS05205	COG2264	protein methyltransferase activity
D9783_RS05215	COG1982	Orn Lys Arg decarboxylase major
D9783_RS05220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9783_RS05225	COG3870	Protein conserved in bacteria
D9783_RS05230	COG1728	Protein conserved in bacteria
D9783_RS05235	COG0470	DNA polymerase III
D9783_RS05240	COG1774	PSP1 C-terminal conserved region
D9783_RS05245	COG4467	Involved in initiation control of chromosome replication
D9783_RS05250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D9783_RS05255	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D9783_RS05260	COG2002	toxin-antitoxin pair type II binding
D9783_RS05270	COG0084	hydrolase, TatD family'
D9783_RS05275	COG3583	domain protein
D9783_RS05275	COG3584	3D domain protein
D9783_RS05300	COG4466	Protein conserved in bacteria
D9783_RS05310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D9783_RS05315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9783_RS05320	COG0251	oxidation-reduction process
D9783_RS05330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D9783_RS05340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D9783_RS05355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D9783_RS05360	COG2002	toxin-antitoxin pair type II binding
D9783_RS05365	COG2244	polysaccharide biosynthetic process
D9783_RS05370	COG3956	TIGRFAM MazG family protein
D9783_RS05375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D9783_RS05390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D9783_RS05395	COG1098	S1 RNA binding domain
D9783_RS05415	COG2208	phosphoserine phosphatase activity
D9783_RS05420	COG2304	oxidoreductase activity
D9783_RS05425	COG0515	serine threonine protein kinase
D9783_RS05435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
D9783_RS05440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D9783_RS05445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
D9783_RS05450	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D9783_RS05455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9783_RS05460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9783_RS05465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9783_RS05470	COG0512	Glutamine amidotransferase of anthranilate synthase
D9783_RS05475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9783_RS05480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D9783_RS05485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D9783_RS05490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D9783_RS05495	COG1396	sequence-specific DNA binding
D9783_RS05500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9783_RS05585	COG5522	Integral membrane protein (intg_mem_TP0381)
D9783_RS05595	COG3880	PFAM UvrB UvrC protein
D9783_RS05600	COG3869	Catalyzes the specific phosphorylation of arginine residues in
D9783_RS05605	COG0542	response to heat
D9783_RS05610	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D9783_RS05615	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
D9783_RS05620	COG4956	integral membrane protein (PIN domain superfamily)
D9783_RS05625	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D9783_RS05630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D9783_RS05635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D9783_RS05640	COG1045	serine acetyltransferase
D9783_RS05645	COG0215	cysteine-tRNA ligase activity
D9783_RS05655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9783_RS05660	COG3688	RNA-binding protein containing a PIN domain
D9783_RS05670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9783_RS05675	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D9783_RS05680	COG0250	Participates in transcription elongation, termination and antitermination
D9783_RS05685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D9783_RS05700	COG0222	ribosome binding
D9783_RS05705	COG2813	Specifically methylates the guanine in position
D9783_RS05710	COG0085	RNA polymerase activity
D9783_RS05715	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D9783_RS05720	COG1358	cellular component organization or biogenesis
D9783_RS05725	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
D9783_RS05730	COG0049	tRNA binding
D9783_RS05740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D9783_RS05755	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D9783_RS05760	COG0088	Forms part of the polypeptide exit tunnel
D9783_RS05770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D9783_RS05775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D9783_RS05780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D9783_RS05785	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D9783_RS05790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
D9783_RS05795	COG0255	Belongs to the universal ribosomal protein uL29 family
D9783_RS05800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D9783_RS05815	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D9783_RS05820	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D9783_RS05830	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D9783_RS05835	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
D9783_RS05840	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
D9783_RS05845	COG1841	ribosomal large subunit assembly
D9783_RS05855	COG0201	protein transport
D9783_RS05860	COG0563	adenylate kinase activity
D9783_RS05865	COG0024	Methionine aminopeptidase
D9783_RS05870	COG2163	COG2163 Ribosomal protein L14E L6E L27E
D9783_RS05875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D9783_RS05880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
D9783_RS05885	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D9783_RS05890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D9783_RS05895	COG0202	RNA polymerase activity
D9783_RS05900	COG0203	ribosomal protein L17
D9783_RS05905	COG1122	ATPase activity
D9783_RS05910	COG1122	ATPase activity
D9783_RS05915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D9783_RS05920	COG0101	tRNA pseudouridine synthase activity
D9783_RS05925	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D9783_RS05930	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D9783_RS05940	COG5002	protein histidine kinase activity
D9783_RS05950	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9783_RS05955	COG0489	protein tyrosine kinase activity
D9783_RS05965	COG2194	sulfuric ester hydrolase activity
D9783_RS05970	COG0726	polysaccharide deacetylase
D9783_RS06050	COG1595	DNA-templated transcription, initiation
D9783_RS06055	COG5662	AntiSigma factor
D9783_RS06060	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D9783_RS06065	COG4856	YbbR-like protein
D9783_RS06070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9783_RS06075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D9783_RS06105	COG1595	DNA-templated transcription, initiation
D9783_RS06120	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9783_RS06125	COG0124	histidyl-tRNA synthetase
D9783_RS06145	COG0392	lysyltransferase activity
D9783_RS06145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
D9783_RS06150	COG0432	Pfam Uncharacterised protein family UPF0047
D9783_RS06160	COG1522	sequence-specific DNA binding
D9783_RS06190	COG4251	negative regulation of phosphorylation
D9783_RS06190	COG5001	Diguanylate cyclase
D9783_RS06190	COG3706	GGDEF domain
D9783_RS06190	COG2203	Gaf domain
D9783_RS06205	COG2094	Belongs to the DNA glycosylase MPG family
D9783_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS06225	COG2814	Major facilitator Superfamily
D9783_RS06240	COG1115	amino acid carrier protein
D9783_RS06245	COG0517	IMP dehydrogenase activity
D9783_RS06255	COG2340	Cysteine-rich secretory protein family
D9783_RS06265	COG0018	arginyl-trna synthetase
D9783_RS06270	COG0772	Belongs to the SEDS family
D9783_RS06290	COG2814	Major facilitator Superfamily
D9783_RS06295	COG0589	response to stress
D9783_RS06300	COG1181	Belongs to the D-alanine--D-alanine ligase family
D9783_RS06305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D9783_RS06320	COG0513	Belongs to the DEAD box helicase family
D9783_RS06330	COG4294	response to UV
D9783_RS06335	COG0705	Rhomboid family
D9783_RS06340	COG0736	holo-[acyl-carrier-protein] synthase activity
D9783_RS06345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D9783_RS06355	COG0864	Transcriptional regulator
D9783_RS06360	COG2337	Toxic component of a toxin-antitoxin (TA) module
D9783_RS06365	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS06370	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS06375	COG2172	sigma factor antagonist activity
D9783_RS06380	COG2208	phosphoserine phosphatase activity
D9783_RS06385	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS06390	COG2172	sigma factor antagonist activity
D9783_RS06395	COG1191	sigma factor activity
D9783_RS06400	COG2208	phosphoserine phosphatase activity
D9783_RS06405	COG2183	response to ionizing radiation
D9783_RS06415	COG3091	SprT-like family
D9783_RS06500	COG0802	atpase or kinase
D9783_RS06505	COG1214	PFAM Peptidase M22, glycoprotease
D9783_RS06510	COG0456	acetyltransferase
D9783_RS06520	COG0488	(ABC) transporter
D9783_RS06525	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
D9783_RS06530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D9783_RS06535	COG0805	protein transport
D9783_RS06550	COG1266	CAAX protease self-immunity
D9783_RS06555	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D9783_RS06560	COG0459	protein refolding
D9783_RS06565	COG0789	Transcriptional regulator
D9783_RS06565	COG4978	Transcriptional regulator
D9783_RS06570	COG2814	Major facilitator Superfamily
D9783_RS06575	COG2259	Doxx family
D9783_RS06580	COG2514	catechol 2,3-dioxygenase activity
D9783_RS06605	COG0534	Mate efflux family protein
D9783_RS06615	COG4608	Belongs to the ABC transporter superfamily
D9783_RS06620	COG0444	Belongs to the ABC transporter superfamily
D9783_RS06625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9783_RS06630	COG0601	transmembrane transport
D9783_RS06635	COG0747	negative chemotaxis
D9783_RS06645	COG2814	Major facilitator Superfamily
D9783_RS06680	COG2972	Histidine kinase
D9783_RS06685	COG2207	Transcriptional regulator
D9783_RS06685	COG4753	response regulator
D9783_RS06690	COG4213	ABC transporter substrate-binding protein
D9783_RS06700	COG4214	carbohydrate transport
D9783_RS06725	COG0546	phosphoglycolate phosphatase activity
D9783_RS06735	COG1215	transferase activity, transferring glycosyl groups
D9783_RS06740	COG1307	EDD domain protein, DegV family
D9783_RS06745	COG0840	transmembrane signaling receptor activity
D9783_RS06745	COG3290	protein histidine kinase activity
D9783_RS06755	COG0647	UMP catabolic process
D9783_RS06760	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9783_RS06775	COG0395	ABC-type sugar transport system, permease component
D9783_RS06790	COG3279	Response regulator of the LytR AlgR family
D9783_RS06795	COG4555	ABC transporter
D9783_RS06800	COG1668	transmembrane transport
D9783_RS06805	COG1595	DNA-templated transcription, initiation
D9783_RS06850	COG2304	oxidoreductase activity
D9783_RS06895	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D9783_RS06905	COG0714	Associated with various cellular activities
D9783_RS06910	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
D9783_RS06915	COG1305	Transglutaminase-like
D9783_RS06920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D9783_RS06920	COG0519	Catalyzes the synthesis of GMP from XMP
D9783_RS06925	COG2252	PERMEase
D9783_RS06930	COG3711	transcriptional antiterminator
D9783_RS06935	COG1263	PTS System
D9783_RS06935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9783_RS06935	COG2190	(PTS) system
D9783_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
D9783_RS06985	COG2720	vancomycin resistance protein
D9783_RS06995	COG0590	tRNA wobble adenosine to inosine editing
D9783_RS07005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D9783_RS07010	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
D9783_RS07020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D9783_RS07025	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D9783_RS07030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D9783_RS07040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D9783_RS07045	COG0047	phosphoribosylformylglycinamidine synthase activity
D9783_RS07055	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D9783_RS07060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D9783_RS07065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D9783_RS07070	COG0138	bifunctional purine biosynthesis protein purh
D9783_RS07075	COG0151	Belongs to the GarS family
D9783_RS07090	COG1470	cell adhesion involved in biofilm formation
D9783_RS07095	COG4496	protein, YerC YecD
D9783_RS07100	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
D9783_RS07105	COG0210	DNA helicase
D9783_RS07110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D9783_RS07115	COG4851	CamS sex pheromone cAM373 precursor
D9783_RS07125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D9783_RS07130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D9783_RS07135	COG2224	Isocitrate lyase
D9783_RS07145	COG5506	Protein of unknown function (DUF1694)
D9783_RS07155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS07160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D9783_RS07165	COG0154	amidase activity
D9783_RS07190	COG1595	DNA-templated transcription, initiation
D9783_RS07210	COG1597	lipid kinase activity
D9783_RS07225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9783_RS07270	COG0784	Response regulator, receiver
D9783_RS07270	COG5002	protein histidine kinase activity
D9783_RS07275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9783_RS07280	COG4191	Histidine kinase
D9783_RS07285	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D9783_RS07290	COG0579	oxidoreductase
D9783_RS07305	COG0346	lactoylglutathione lyase activity
D9783_RS07350	COG3344	reverse transcriptase
D9783_RS07385	COG0706	membrane insertase activity
D9783_RS07410	COG0456	acetyltransferase
D9783_RS07415	COG0110	maltose O-acetyltransferase activity
D9783_RS07425	COG1191	sigma factor activity
D9783_RS07430	COG1131	(ABC) transporter
D9783_RS07460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
D9783_RS07465	COG0235	Class ii aldolase
D9783_RS07470	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
D9783_RS07475	COG1850	ribulose-bisphosphate carboxylase activity
D9783_RS07480	COG0436	Aminotransferase
D9783_RS07485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9783_RS07490	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
D9783_RS07495	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
D9783_RS07515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9783_RS07520	COG0363	glucosamine-6-phosphate deaminase activity
D9783_RS07525	COG3275	phosphorelay sensor kinase activity
D9783_RS07535	COG1966	Carbon starvation protein
D9783_RS07540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9783_RS07555	COG1653	transport
D9783_RS07560	COG1175	transmembrane transport
D9783_RS07565	COG0395	ABC-type sugar transport system, permease component
D9783_RS07585	COG1073	alpha beta
D9783_RS07590	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D9783_RS07595	COG1937	Protein conserved in bacteria
D9783_RS07600	COG2608	mercury ion transmembrane transporter activity
D9783_RS07605	COG2217	Heavy metal translocating P-type atpase
D9783_RS07615	COG2268	Band 7 protein
D9783_RS07630	COG3239	Fatty acid desaturase
D9783_RS07635	COG4585	Histidine kinase
D9783_RS07640	COG2197	response regulator
D9783_RS07645	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9783_RS07660	COG0789	Transcriptional regulator
D9783_RS07665	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9783_RS07685	COG2267	carboxylic ester hydrolase activity
D9783_RS07695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9783_RS07720	COG0166	Belongs to the GPI family
D9783_RS07730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9783_RS07735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D9783_RS07750	COG2966	Psort location CytoplasmicMembrane, score
D9783_RS07760	COG4166	transmembrane transport
D9783_RS07765	COG4166	transmembrane transport
D9783_RS07780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D9783_RS07790	COG2197	response regulator
D9783_RS07795	COG4585	Histidine kinase
D9783_RS07805	COG1132	(ABC) transporter
D9783_RS07810	COG1132	(ABC) transporter
D9783_RS07830	COG1960	acyl-CoA dehydrogenase activity
D9783_RS07835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D9783_RS07865	COG2364	Membrane
D9783_RS07880	COG2032	superoxide dismutase activity
D9783_RS07885	COG2814	Major facilitator Superfamily
D9783_RS07885	COG0477	Major facilitator Superfamily
D9783_RS07890	COG4533	DNA binding
D9783_RS07900	COG0488	(ABC) transporter
D9783_RS07910	COG4120	Belongs to the binding-protein-dependent transport system permease family
D9783_RS07915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9783_RS07915	COG1116	anion transmembrane transporter activity
D9783_RS07920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D9783_RS07925	COG0129	dihydroxy-acid dehydratase activity
D9783_RS07935	COG0028	Belongs to the TPP enzyme family
D9783_RS07940	COG0440	acetolactate synthase activity
D9783_RS07945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D9783_RS07950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9783_RS07960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D9783_RS07965	COG0066	3-isopropylmalate dehydratase activity
D9783_RS07970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D9783_RS07980	COG0460	homoserine dehydrogenase
D9783_RS07985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D9783_RS07990	COG0083	homoserine kinase activity
D9783_RS07995	COG5002	protein histidine kinase activity
D9783_RS08005	COG0154	amidase activity
D9783_RS08025	COG0395	ABC-type sugar transport system, permease component
D9783_RS08035	COG3842	ATPase activity
D9783_RS08050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
D9783_RS08070	COG5566	PFAM Mor transcription activator
D9783_RS08080	COG3290	protein histidine kinase activity
D9783_RS08080	COG0840	transmembrane signaling receptor activity
D9783_RS08085	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9783_RS08125	COG2205	protein histidine kinase activity
D9783_RS08130	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
D9783_RS08135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D9783_RS08150	COG2190	(PTS) system
D9783_RS08150	COG1263	PTS System
D9783_RS08150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9783_RS08165	COG2244	polysaccharide biosynthetic process
D9783_RS08205	COG4585	Histidine kinase
D9783_RS08210	COG2197	response regulator
D9783_RS08220	COG1063	alcohol dehydrogenase
D9783_RS08230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D9783_RS08250	COG1764	response to oxidative stress
D9783_RS08260	COG0494	nUDIX hydrolase
D9783_RS08270	COG2217	Heavy metal translocating P-type atpase
D9783_RS08275	COG0456	acetyltransferase
D9783_RS08290	COG0640	Transcriptional regulator
D9783_RS08295	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
D9783_RS08300	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9783_RS08310	COG4589	Belongs to the CDS family
D9783_RS08325	COG4533	DNA binding
D9783_RS08355	COG0561	phosphatase activity
D9783_RS08365	COG0288	reversible hydration of carbon dioxide
D9783_RS08375	COG0488	(ABC) transporter
D9783_RS08385	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
D9783_RS08410	COG0778	Nitroreductase
D9783_RS08425	COG1595	DNA-templated transcription, initiation
D9783_RS08430	COG1077	Cell shape determining protein MreB Mrl
D9783_RS08435	COG0840	transmembrane signaling receptor activity
D9783_RS08440	COG1744	ABC transporter substrate-binding protein PnrA-like
D9783_RS08450	COG0702	epimerase
D9783_RS08470	COG2309	aminopeptidase activity
D9783_RS08475	COG0745	RESPONSE REGULATOR receiver
D9783_RS08485	COG1215	transferase activity, transferring glycosyl groups
D9783_RS08495	COG1959	2 iron, 2 sulfur cluster binding
D9783_RS08510	COG0840	transmembrane signaling receptor activity
D9783_RS08515	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D9783_RS08520	COG1360	Flagellar Motor Protein
D9783_RS08525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D9783_RS08525	COG1522	sequence-specific DNA binding
D9783_RS08530	COG2313	pseudouridylate synthase activity
D9783_RS08535	COG0494	nUDIX hydrolase
D9783_RS08540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D9783_RS08550	COG4840	Belongs to the UPF0435 family
D9783_RS08555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D9783_RS08560	COG4980	gas vesicle protein
D9783_RS08565	COG1295	ribonuclease BN
D9783_RS08570	COG2217	Heavy metal translocating P-type atpase
D9783_RS08575	COG0477	Major facilitator Superfamily
D9783_RS08585	COG3871	stress protein (general stress protein 26)
D9783_RS08630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9783_RS08635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9783_RS08640	COG0840	transmembrane signaling receptor activity
D9783_RS08640	COG5278	phosphoserine phosphatase activity
D9783_RS08650	COG2072	flavoprotein involved in K transport
D9783_RS08655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D9783_RS08660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9783_RS08670	COG0668	transmembrane transport
D9783_RS08685	COG1683	Conserved Protein
D9783_RS08700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D9783_RS08705	COG1309	transcriptional regulator
D9783_RS08715	COG3290	protein histidine kinase activity
D9783_RS08715	COG0840	transmembrane signaling receptor activity
D9783_RS08740	COG1309	transcriptional regulator
D9783_RS08745	COG2814	Major facilitator Superfamily
D9783_RS08750	COG0840	transmembrane signaling receptor activity
D9783_RS08760	COG0662	Cupin 2, conserved barrel domain protein
D9783_RS08765	COG2304	oxidoreductase activity
D9783_RS08785	COG0488	(ABC) transporter
D9783_RS08795	COG1742	UPF0060 membrane protein
D9783_RS08825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D9783_RS08825	COG2199	diguanylate cyclase activity
D9783_RS08835	COG0412	Dienelactone hydrolase
D9783_RS08850	COG1349	DNA-binding transcription factor activity
D9783_RS08855	COG1175	transmembrane transport
D9783_RS08860	COG0395	ABC-type sugar transport system, permease component
D9783_RS08895	COG1131	(ABC) transporter
D9783_RS08900	COG0842	Transport permease protein
D9783_RS08945	COG1070	Carbohydrate kinase
D9783_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D9783_RS08965	COG0667	Aldo Keto reductase
D9783_RS08975	COG5578	integral membrane protein
D9783_RS08980	COG2972	Histidine kinase
D9783_RS08985	COG2207	Transcriptional regulator
D9783_RS08985	COG4753	response regulator
D9783_RS08990	COG1653	transport
D9783_RS08995	COG1175	transmembrane transport
D9783_RS09000	COG0395	ABC-type sugar transport system, permease component
D9783_RS09010	COG0300	oxidoreductase activity
D9783_RS09020	COG1902	pentaerythritol trinitrate reductase activity
D9783_RS09075	COG0671	phosphoesterase, PA-phosphatase related
D9783_RS09140	COG1131	(ABC) transporter
D9783_RS09160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9783_RS09165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D9783_RS09165	COG1263	PTS System
D9783_RS09165	COG2190	(PTS) system
D9783_RS09170	COG2723	6-phospho-beta-galactosidase activity
D9783_RS09190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS09195	COG0840	transmembrane signaling receptor activity
D9783_RS09195	COG5278	phosphoserine phosphatase activity
D9783_RS09205	COG4191	Histidine kinase
D9783_RS09240	COG0322	excinuclease ABC activity
D9783_RS09245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D9783_RS09250	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D9783_RS09255	COG1733	regulation of RNA biosynthetic process
D9783_RS09260	COG3973	AAA domain
D9783_RS09275	COG3620	sequence-specific DNA binding
D9783_RS09280	COG0006	proline dipeptidase activity
D9783_RS09290	COG1309	transcriptional regulator
D9783_RS09315	COG3711	transcriptional antiterminator
D9783_RS09340	COG2819	hydrolase of the alpha beta superfamily
D9783_RS09385	COG0300	oxidoreductase activity
D9783_RS09440	COG1278	Cold shock
D9783_RS09450	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9783_RS09450	COG1902	pentaerythritol trinitrate reductase activity
D9783_RS09455	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS09480	COG2801	Transposase and inactivated derivatives
D9783_RS09540	COG1061	Type III restriction enzyme res subunit
D9783_RS09630	COG0702	epimerase
D9783_RS09635	COG1959	2 iron, 2 sulfur cluster binding
D9783_RS09650	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS09655	COG2226	methyltransferase
D9783_RS09660	COG1073	alpha beta
D9783_RS09665	COG0277	FAD linked oxidase domain protein
D9783_RS09690	COG3655	Transcriptional regulator
D9783_RS09695	COG0840	transmembrane signaling receptor activity
D9783_RS09710	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS09710	COG2202	Pas domain
D9783_RS09740	COG1309	transcriptional regulator
D9783_RS09745	COG2267	carboxylic ester hydrolase activity
D9783_RS09765	COG0697	spore germination
D9783_RS09770	COG0531	amino acid
D9783_RS09785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D9783_RS09800	COG1695	Transcriptional regulator
D9783_RS09825	COG5002	protein histidine kinase activity
D9783_RS09830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS09865	COG1253	flavin adenine dinucleotide binding
D9783_RS09890	COG0840	transmembrane signaling receptor activity
D9783_RS09895	COG4869	propanediol catabolic process
D9783_RS09935	COG1472	Belongs to the glycosyl hydrolase 3 family
D9783_RS09940	COG1803	Methylglyoxal synthase
D9783_RS09945	COG0840	transmembrane signaling receptor activity
D9783_RS09945	COG3290	protein histidine kinase activity
D9783_RS09950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D9783_RS09985	COG0386	Belongs to the glutathione peroxidase family
D9783_RS10015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9783_RS10020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9783_RS10025	COG0390	transport system, permease component
D9783_RS10040	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS10045	COG1733	regulation of RNA biosynthetic process
D9783_RS10050	COG3153	acetyltransferase
D9783_RS10050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9783_RS10055	COG0456	acetyltransferase
D9783_RS10115	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9783_RS10125	COG0840	transmembrane signaling receptor activity
D9783_RS10130	COG4682	membrane
D9783_RS10135	COG0704	Plays a role in the regulation of phosphate uptake
D9783_RS10165	COG3340	Belongs to the peptidase S51 family
D9783_RS10170	COG3290	protein histidine kinase activity
D9783_RS10170	COG0840	transmembrane signaling receptor activity
D9783_RS10175	COG3773	Cell wall hydrolase
D9783_RS10215	COG0577	efflux transmembrane transporter activity
D9783_RS10220	COG1136	(ABC) transporter
D9783_RS10225	COG0642	Histidine kinase
D9783_RS10230	COG0745	RESPONSE REGULATOR receiver
D9783_RS10245	COG0561	phosphatase activity
D9783_RS10250	COG1335	isochorismatase
D9783_RS10265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D9783_RS10270	COG1940	carbohydrate kinase activity
D9783_RS10275	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D9783_RS10280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D9783_RS10285	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D9783_RS10295	COG3290	protein histidine kinase activity
D9783_RS10300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D9783_RS10355	COG0840	transmembrane signaling receptor activity
D9783_RS10360	COG5002	protein histidine kinase activity
D9783_RS10370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS10380	COG1595	DNA-templated transcription, initiation
D9783_RS10405	COG4191	Histidine kinase
D9783_RS10410	COG4191	Histidine kinase
D9783_RS10450	COG0494	nUDIX hydrolase
D9783_RS10470	COG0861	Integral membrane protein TerC family
D9783_RS10490	COG3300	MHYT domain
D9783_RS10490	COG5001	Diguanylate cyclase
D9783_RS10500	COG0778	Nitroreductase
D9783_RS10520	COG0523	cobalamin synthesis protein
D9783_RS10525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D9783_RS10530	COG0701	Predicted permease
D9783_RS10535	COG3689	TIGRFAM TIGR03943 family protein
D9783_RS10545	COG0701	Predicted permease
D9783_RS10590	COG1404	Belongs to the peptidase S8 family
D9783_RS10600	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D9783_RS10615	COG0861	Integral membrane protein TerC family
D9783_RS10630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D9783_RS10635	COG0778	Nitroreductase
D9783_RS10650	COG4122	O-methyltransferase activity
D9783_RS10655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9783_RS10660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS10665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS10670	COG2814	Major facilitator Superfamily
D9783_RS10675	COG0840	transmembrane signaling receptor activity
D9783_RS10690	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS10695	COG1404	Belongs to the peptidase S8 family
D9783_RS10735	COG0791	NLP P60 protein
D9783_RS10750	COG1247	-acetyltransferase
D9783_RS10775	COG0840	transmembrane signaling receptor activity
D9783_RS10775	COG5278	phosphoserine phosphatase activity
D9783_RS10780	COG2124	cytochrome p450
D9783_RS10785	COG1476	TRANSCRIPTIONal
D9783_RS10805	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9783_RS10805	COG1024	Enoyl-CoA hydratase
D9783_RS10810	COG2201	protein-glutamate methylesterase activity
D9783_RS10825	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9783_RS10830	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS10840	COG2311	Membrane
D9783_RS10850	COG1609	Transcriptional regulator
D9783_RS10855	COG1879	ABC-type sugar transport system periplasmic component
D9783_RS10860	COG1129	ABC transporter
D9783_RS10865	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9783_RS10885	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS10890	COG0590	tRNA wobble adenosine to inosine editing
D9783_RS10930	COG3813	Protein conserved in bacteria
D9783_RS10950	COG1309	transcriptional regulator
D9783_RS10955	COG1131	(ABC) transporter
D9783_RS10990	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS11030	COG0745	RESPONSE REGULATOR receiver
D9783_RS11035	COG3850	Histidine kinase
D9783_RS11035	COG5002	protein histidine kinase activity
D9783_RS11045	COG1136	(ABC) transporter
D9783_RS11055	COG0840	transmembrane signaling receptor activity
D9783_RS11070	COG1609	Transcriptional regulator
D9783_RS11085	COG2112	serine threonine protein kinase
D9783_RS11095	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D9783_RS11105	COG2267	carboxylic ester hydrolase activity
D9783_RS11110	COG1033	growth of symbiont in host cell
D9783_RS11110	COG2409	Drug exporters of the RND superfamily
D9783_RS11130	COG1960	acyl-CoA dehydrogenase activity
D9783_RS11145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D9783_RS11150	COG2011	ABC-type metal ion transport system permease component
D9783_RS11175	COG1090	epimerase
D9783_RS11180	COG2137	regulation of response to DNA damage stimulus
D9783_RS11185	COG0300	oxidoreductase activity
D9783_RS11205	COG1988	membrane-bound metal-dependent
D9783_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS11250	COG3557	Belongs to the UPF0374 family
D9783_RS11255	COG1132	(ABC) transporter
D9783_RS11260	COG0444	Belongs to the ABC transporter superfamily
D9783_RS11265	COG4608	Belongs to the ABC transporter superfamily
D9783_RS11270	COG0747	negative chemotaxis
D9783_RS11275	COG0601	transmembrane transport
D9783_RS11280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9783_RS11285	COG4129	membrane
D9783_RS11290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9783_RS11295	COG4555	ABC transporter
D9783_RS11315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D9783_RS11320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9783_RS11325	COG2096	Adenosyltransferase
D9783_RS11330	COG0735	belongs to the Fur family
D9783_RS11445	COG3382	B3 4 domain protein
D9783_RS11450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D9783_RS11460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D9783_RS11465	COG0778	Nitroreductase
D9783_RS11475	COG2766	serine protein kinase
D9783_RS11480	COG2718	Belongs to the UPF0229 family
D9783_RS11495	COG1511	domain protein
D9783_RS11500	COG1309	transcriptional regulator
D9783_RS11505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D9783_RS11510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9783_RS11515	COG0561	phosphatase activity
D9783_RS11520	COG0516	GMP reductase activity
D9783_RS11530	COG3711	transcriptional antiterminator
D9783_RS11550	COG0039	L-malate dehydrogenase activity
D9783_RS11570	COG0745	RESPONSE REGULATOR receiver
D9783_RS11575	COG2205	protein histidine kinase activity
D9783_RS11580	COG0753	catalase activity
D9783_RS11585	COG0456	acetyltransferase
D9783_RS11590	COG1280	lysine exporter protein (LysE YggA)
D9783_RS11600	COG3546	catalase activity
D9783_RS11605	COG1131	(ABC) transporter
D9783_RS11615	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9783_RS11620	COG1349	DNA-binding transcription factor activity
D9783_RS11625	COG1105	Belongs to the carbohydrate kinase PfkB family
D9783_RS11630	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D9783_RS11630	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9783_RS11630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D9783_RS11675	COG0217	transcriptional regulatory protein
D9783_RS11680	COG1376	ErfK ybiS ycfS ynhG family protein
D9783_RS11685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
D9783_RS11690	COG2309	aminopeptidase activity
D9783_RS11695	COG1834	amidinotransferase
D9783_RS11705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9783_RS11710	COG5577	PFAM Coat F domain
D9783_RS11720	COG2252	PERMEase
D9783_RS11725	COG4187	Peptidase family M20/M25/M40
D9783_RS11740	COG1970	mechanosensitive ion channel activity
D9783_RS11760	COG1132	(ABC) transporter
D9783_RS11770	COG2814	Major facilitator Superfamily
D9783_RS11775	COG3973	AAA domain
D9783_RS11780	COG0656	L-ascorbic acid biosynthetic process
D9783_RS11785	COG2259	Doxx family
D9783_RS11790	COG0655	NAD(P)H dehydrogenase (quinone) activity
D9783_RS11795	COG0564	pseudouridine synthase activity
D9783_RS11805	COG3118	belongs to the thioredoxin family
D9783_RS11810	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D9783_RS11815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D9783_RS11815	COG3153	acetyltransferase
D9783_RS11820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D9783_RS11825	COG4585	Histidine kinase
D9783_RS11825	COG2203	Gaf domain
D9783_RS11830	COG2197	response regulator
D9783_RS11880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9783_RS11880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9783_RS11890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9783_RS11940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9783_RS11960	COG2719	SpoVR family
D9783_RS11975	COG4989	oxidoreductase activity
D9783_RS11985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9783_RS11995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9783_RS12005	COG0084	hydrolase, TatD family'
D9783_RS12015	COG1533	DNA photolyase activity
D9783_RS12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS12030	COG0662	Cupin 2, conserved barrel domain protein
D9783_RS12040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D9783_RS12045	COG2814	Major facilitator Superfamily
D9783_RS12050	COG1595	DNA-templated transcription, initiation
D9783_RS12065	COG0393	Putative heavy-metal-binding
D9783_RS12070	COG1132	(ABC) transporter
D9783_RS12075	COG1132	(ABC) transporter
D9783_RS12100	COG0702	epimerase
D9783_RS12105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9783_RS12110	COG0765	amino acid transport
D9783_RS12115	COG1126	abc transporter atp-binding protein
D9783_RS12135	COG3842	ATPase activity
D9783_RS12140	COG2508	Transcriptional regulator
D9783_RS12170	COG0189	ligase activity
D9783_RS12175	COG0189	ligase activity
D9783_RS12195	COG0561	phosphatase activity
D9783_RS12200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9783_RS12205	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS12215	COG0384	phenazine biosynthesis protein PhzF
D9783_RS12230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
D9783_RS12235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D9783_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS12255	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS12260	COG1024	Enoyl-CoA hydratase
D9783_RS12270	COG4152	abc transporter atp-binding protein
D9783_RS12275	COG1668	transmembrane transport
D9783_RS12280	COG0420	3'-5' exonuclease activity
D9783_RS12285	COG4717	serine-type aminopeptidase activity
D9783_RS12300	COG5002	protein histidine kinase activity
D9783_RS12315	COG3340	Belongs to the peptidase S51 family
D9783_RS12320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D9783_RS12355	COG1846	Transcriptional regulator
D9783_RS12375	COG0537	adenosine 5'-monophosphoramidase activity
D9783_RS12380	COG1131	(ABC) transporter
D9783_RS12385	COG4473	ABC transporter
D9783_RS12395	COG0673	inositol 2-dehydrogenase activity
D9783_RS12400	COG0561	phosphatase activity
D9783_RS12410	COG1349	DNA-binding transcription factor activity
D9783_RS12425	COG1473	amidohydrolase
D9783_RS12440	COG4585	Histidine kinase
D9783_RS12445	COG2197	response regulator
D9783_RS12450	COG1335	isochorismatase
D9783_RS12455	COG2329	Antibiotic biosynthesis monooxygenase
D9783_RS12460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D9783_RS12465	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D9783_RS12470	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
D9783_RS12480	COG1234	tRNA 3'-trailer cleavage
D9783_RS12485	COG0095	Lipoate-protein ligase
D9783_RS12490	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS12495	COG1024	Enoyl-CoA hydratase
D9783_RS12500	COG1396	sequence-specific DNA binding
D9783_RS12505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D9783_RS12515	COG0501	Belongs to the peptidase M48B family
D9783_RS12540	COG4946	Tricorn protease homolog
D9783_RS12540	COG1506	peptidase
D9783_RS12540	COG0823	Involved in the tonB-independent uptake of proteins
D9783_RS12545	COG0398	Pfam SNARE associated Golgi protein
D9783_RS12560	COG3437	response regulator, receiver
D9783_RS12560	COG2770	Histidine kinase
D9783_RS12600	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS12605	COG0183	Belongs to the thiolase family
D9783_RS12615	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS12620	COG4876	unkown
D9783_RS12635	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D9783_RS12640	COG1074	ATP-dependent DNA helicase activity
D9783_RS12650	COG1403	HNH endonuclease
D9783_RS12685	COG2311	Membrane
D9783_RS12690	COG0179	Fumarylacetoacetate (FAA) hydrolase
D9783_RS12700	COG5001	Diguanylate cyclase
D9783_RS12700	COG3300	MHYT domain
D9783_RS12710	COG0367	asparagine synthase
D9783_RS12725	COG1562	ergosterol biosynthetic process
D9783_RS12730	COG0534	Mate efflux family protein
D9783_RS12740	COG2182	Extracellular solute-binding protein
D9783_RS12745	COG1175	transmembrane transport
D9783_RS12750	COG3833	ABC-type maltose transport systems, permease component
D9783_RS12755	COG1874	Beta-galactosidase
D9783_RS12755	COG0366	Alpha amylase catalytic
D9783_RS12760	COG1609	Transcriptional regulator
D9783_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS12770	COG0446	pyridine nucleotide-disulphide oxidoreductase
D9783_RS12785	COG1307	EDD domain protein, DegV family
D9783_RS12790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS12805	COG0561	phosphatase activity
D9783_RS12810	COG1073	alpha beta
D9783_RS12815	COG2151	metal-sulfur cluster biosynthetic enzyme
D9783_RS12820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D9783_RS12825	COG1968	undecaprenyl-diphosphatase activity
D9783_RS12845	COG2267	carboxylic ester hydrolase activity
D9783_RS12855	COG1744	ABC transporter substrate-binding protein PnrA-like
D9783_RS12870	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9783_RS12875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D9783_RS12880	COG5504	Zn-dependent protease
D9783_RS12895	COG0180	Tryptophanyl-tRNA synthetase
D9783_RS12905	COG4166	transmembrane transport
D9783_RS12910	COG0601	transmembrane transport
D9783_RS12915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D9783_RS12920	COG0444	Belongs to the ABC transporter superfamily
D9783_RS12925	COG4608	Belongs to the ABC transporter superfamily
D9783_RS12940	COG0456	acetyltransferase
D9783_RS12945	COG1393	Belongs to the ArsC family
D9783_RS12955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D9783_RS12965	COG1164	Oligoendopeptidase f
D9783_RS12975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9783_RS12980	COG2346	COG2346, Truncated hemoglobins
D9783_RS12985	COG0741	lytic transglycosylase activity
D9783_RS12990	COG4116	CYTH
D9783_RS13000	COG2357	RelA SpoT domain protein
D9783_RS13010	COG0564	pseudouridine synthase activity
D9783_RS13015	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D9783_RS13020	COG2239	Acts as a magnesium transporter
D9783_RS13025	COG0569	domain protein
D9783_RS13025	COG0475	glutathione-regulated potassium exporter activity
D9783_RS13030	COG2318	DinB family
D9783_RS13065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D9783_RS13075	COG2323	membrane
D9783_RS13100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS13105	COG2323	membrane
D9783_RS13110	COG2153	protein acetylation
D9783_RS13115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
D9783_RS13120	COG2382	esterase
D9783_RS13125	COG2358	TRAP transporter, solute receptor (TAXI family
D9783_RS13140	COG0840	transmembrane signaling receptor activity
D9783_RS13155	COG0582	viral genome integration into host DNA
D9783_RS13180	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D9783_RS13195	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D9783_RS13220	COG0366	Alpha amylase catalytic
D9783_RS13225	COG3773	Cell wall hydrolase
D9783_RS13230	COG2364	Membrane
D9783_RS13240	COG0671	phosphoesterase, PA-phosphatase related
D9783_RS13245	COG0385	Bile acid
D9783_RS13250	COG3663	DNA glycosylase
D9783_RS13265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS13275	COG3852	Histidine kinase
D9783_RS13280	COG1657	PFAM Prenyltransferase squalene oxidase
D9783_RS13290	COG1363	Peptidase, m42
D9783_RS13295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D9783_RS13300	COG1764	response to oxidative stress
D9783_RS13305	COG3706	GGDEF domain
D9783_RS13315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D9783_RS13320	COG5001	Diguanylate cyclase
D9783_RS13320	COG3300	MHYT domain
D9783_RS13340	COG1191	sigma factor activity
D9783_RS13355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9783_RS13365	COG5002	protein histidine kinase activity
D9783_RS13370	COG0640	Transcriptional regulator
D9783_RS13380	COG0737	Belongs to the 5'-nucleotidase family
D9783_RS13385	COG1846	Transcriptional regulator
D9783_RS13390	COG3949	Membrane
D9783_RS13400	COG4873	Protein conserved in bacteria
D9783_RS13415	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS13425	COG0714	Associated with various cellular activities
D9783_RS13460	COG0436	Aminotransferase
D9783_RS13465	COG0598	Magnesium transport protein CorA
D9783_RS13480	COG0835	chemotaxis
D9783_RS13480	COG0784	Response regulator, receiver
D9783_RS13495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D9783_RS13510	COG5001	Diguanylate cyclase
D9783_RS13510	COG3300	MHYT domain
D9783_RS13520	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS13525	COG2200	EAL domain
D9783_RS13550	COG4703	Protein of unknown function (DUF1797)
D9783_RS13555	COG0517	IMP dehydrogenase activity
D9783_RS13560	COG2814	Major facilitator Superfamily
D9783_RS13565	COG0583	DNA-binding transcription factor activity
D9783_RS13570	COG2171	N-acyltransferase activity
D9783_RS13575	COG1473	amidohydrolase
D9783_RS13585	COG1131	(ABC) transporter
D9783_RS13600	COG0714	Associated with various cellular activities
D9783_RS13620	COG0668	transmembrane transport
D9783_RS13625	COG0450	alkyl hydroperoxide reductase
D9783_RS13630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS13635	COG1132	(ABC) transporter
D9783_RS13640	COG1132	(ABC) transporter
D9783_RS13650	COG1271	oxidase subunit
D9783_RS13655	COG1294	oxidase, subunit
D9783_RS13660	COG0569	domain protein
D9783_RS13665	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9783_RS13670	COG5503	Protein of unknown function (DUF1447)
D9783_RS13675	COG0561	phosphatase activity
D9783_RS13680	COG0242	peptide deformylase activity
D9783_RS13695	COG0022	dehydrogenase e1 component
D9783_RS13700	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9783_RS13710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS13720	COG0726	polysaccharide deacetylase
D9783_RS13730	COG1982	Orn Lys Arg decarboxylase major
D9783_RS13740	COG4476	Belongs to the UPF0223 family
D9783_RS13755	COG0483	inositol monophosphate 1-phosphatase activity
D9783_RS13765	COG1217	gtp-binding protein TYPA
D9783_RS13780	COG4896	Protein conserved in bacteria
D9783_RS13795	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D9783_RS13800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
D9783_RS13805	COG2066	Belongs to the glutaminase family
D9783_RS13810	COG4838	Belongs to the UPF0358 family
D9783_RS13815	COG0772	Belongs to the SEDS family
D9783_RS13820	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9783_RS13840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9783_RS13855	COG3336	cytochrome c oxidase
D9783_RS13870	COG0628	permease
D9783_RS13880	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D9783_RS13885	COG2340	Cysteine-rich secretory protein family
D9783_RS13910	COG3679	Belongs to the UPF0342 family
D9783_RS13945	COG0742	ribosomal rna small subunit methyltransferase
D9783_RS13950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
D9783_RS13955	COG3314	Sporulation integral membrane protein YlbJ
D9783_RS13960	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9783_RS13965	COG3480	Lon protease (S16) C-terminal proteolytic domain
D9783_RS13975	COG1399	metal-binding, possibly nucleic acid-binding protein
D9783_RS13980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
D9783_RS13985	COG1024	Enoyl-CoA hydratase
D9783_RS13995	COG0454	-acetyltransferase
D9783_RS14000	COG0439	Biotin carboxylase
D9783_RS14005	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
D9783_RS14010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9783_RS14015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D9783_RS14030	COG2001	Belongs to the MraZ family
D9783_RS14035	COG0275	rRNA processing
D9783_RS14040	COG4839	cell division protein FtsL
D9783_RS14045	COG0768	penicillin binding
D9783_RS14050	COG0768	penicillin binding
D9783_RS14065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D9783_RS14070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D9783_RS14075	COG0772	Belongs to the SEDS family
D9783_RS14080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D9783_RS14085	COG3879	Bacterial protein of unknown function (DUF881)
D9783_RS14090	COG3879	Bacterial protein of unknown function (DUF881)
D9783_RS14095	COG3856	small basic protein
D9783_RS14100	COG0849	cell division
D9783_RS14105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D9783_RS14115	COG1191	sigma factor activity
D9783_RS14120	COG1191	sigma factor activity
D9783_RS14125	COG1873	PFAM PRC-barrel domain
D9783_RS14130	COG1496	oxidoreductase activity
D9783_RS14135	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D9783_RS14140	COG1799	cell septum assembly
D9783_RS14145	COG0762	integral membrane protein
D9783_RS14150	COG2302	S4 RNA-binding domain
D9783_RS14155	COG3599	regulation of cell shape
D9783_RS14160	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D9783_RS14170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D9783_RS14175	COG0564	pseudouridine synthase activity
D9783_RS14180	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
D9783_RS14185	COG2233	PERMEase
D9783_RS14190	COG0540	Belongs to the ATCase OTCase family
D9783_RS14195	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D9783_RS14215	COG0167	dihydroorotate dehydrogenase activity
D9783_RS14230	COG4895	conserved protein (DUF2196)
D9783_RS14240	COG1051	belongs to the nudix hydrolase family
D9783_RS14245	COG1279	arginine transmembrane transporter activity
D9783_RS14255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D9783_RS14260	COG1561	YicC-like family, N-terminal region
D9783_RS14270	COG0194	GDP metabolic process
D9783_RS14275	COG1758	RNA polymerase activity
D9783_RS14280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9783_RS14285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D9783_RS14290	COG0242	peptide deformylase activity
D9783_RS14295	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D9783_RS14300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9783_RS14300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D9783_RS14305	COG0631	protein serine/threonine phosphatase activity
D9783_RS14310	COG2815	serine threonine protein kinase
D9783_RS14310	COG0515	serine threonine protein kinase
D9783_RS14315	COG1162	GTPase activity
D9783_RS14320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D9783_RS14325	COG1564	THIamine pyrophosphokinase
D9783_RS14335	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D9783_RS14340	COG1302	Protein conserved in bacteria
D9783_RS14345	COG1461	Dihydroxyacetone kinase
D9783_RS14350	COG1760	l-serine dehydratase
D9783_RS14355	COG1760	l-serine dehydratase
D9783_RS14360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D9783_RS14375	COG0416	fatty acid biosynthetic process
D9783_RS14380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D9783_RS14385	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS14390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D9783_RS14400	COG1196	nuclear chromosome segregation
D9783_RS14405	COG0552	protein localization to endoplasmic reticulum
D9783_RS14410	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
D9783_RS14415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D9783_RS14420	COG0228	four-way junction DNA binding
D9783_RS14425	COG1837	Belongs to the UPF0109 family
D9783_RS14435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D9783_RS14440	COG0336	Belongs to the RNA methyltransferase TrmD family
D9783_RS14445	COG0335	large ribosomal subunit rRNA binding
D9783_RS14470	COG2257	FlhB HrpN YscU SpaS Family
D9783_RS14480	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
D9783_RS14485	COG0758	DNA mediated transformation
D9783_RS14490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9783_RS14495	COG4974	Belongs to the 'phage' integrase family
D9783_RS14500	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D9783_RS14505	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D9783_RS14510	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D9783_RS14515	COG1815	bacterial-type flagellum-dependent cell motility
D9783_RS14520	COG1558	bacterial-type flagellum-dependent cell motility
D9783_RS14525	COG1677	Flagellar hook-basal body complex protein FliE
D9783_RS14530	COG1766	The M ring may be actively involved in energy transduction
D9783_RS14535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9783_RS14545	COG1157	protein secretion by the type III secretion system
D9783_RS14550	COG2882	bacterial-type flagellum organization
D9783_RS14565	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D9783_RS14580	COG1582	Flagellar protein (FlbD)
D9783_RS14585	COG1580	Controls the rotational direction of flagella during chemotaxis
D9783_RS14590	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9783_RS14595	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D9783_RS14595	COG1776	CheC inhibitor of MCP methylation
D9783_RS14600	COG2201	protein-glutamate methylesterase activity
D9783_RS14605	COG3190	flagellar
D9783_RS14610	COG1338	Plays a role in the flagellum-specific transport system
D9783_RS14615	COG1987	bacterial-type flagellum assembly
D9783_RS14620	COG1684	flagellar biosynthetic protein fliR
D9783_RS14625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9783_RS14630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D9783_RS14635	COG1419	protein localization to endoplasmic reticulum
D9783_RS14640	COG0455	bacterial-type flagellum organization
D9783_RS14645	COG2201	protein-glutamate methylesterase activity
D9783_RS14650	COG0643	Histidine kinase
D9783_RS14650	COG2198	Histidine kinase
D9783_RS14655	COG0835	chemotaxis
D9783_RS14660	COG1776	CheC inhibitor of MCP methylation
D9783_RS14665	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
D9783_RS14675	COG1191	sigma factor activity
D9783_RS14690	COG0052	Belongs to the universal ribosomal protein uS2 family
D9783_RS14700	COG0528	UMP kinase activity
D9783_RS14705	COG0233	cytoplasmic translational termination
D9783_RS14710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D9783_RS14715	COG4589	Belongs to the CDS family
D9783_RS14720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D9783_RS14725	COG0750	zinc metalloprotease
D9783_RS14730	COG0442	prolyl-tRNA aminoacylation
D9783_RS14735	COG2176	DNA-directed DNA polymerase activity
D9783_RS14740	COG0779	Required for maturation of 30S ribosomal subunits
D9783_RS14745	COG0195	Participates in both transcription termination and antitermination
D9783_RS14750	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D9783_RS14755	COG1358	cellular component organization or biogenesis
D9783_RS14765	COG1550	Protein conserved in bacteria
D9783_RS14780	COG0196	riboflavin kinase activity
D9783_RS14785	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D9783_RS14790	COG1185	polyribonucleotide nucleotidyltransferase activity
D9783_RS14795	COG0726	polysaccharide deacetylase
D9783_RS14800	COG0612	Peptidase, M16
D9783_RS14805	COG1873	PFAM PRC-barrel domain
D9783_RS14810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D9783_RS14815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D9783_RS14820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D9783_RS14825	COG0527	aspartate kinase activity
D9783_RS14835	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9783_RS14840	COG0740	serine-type endopeptidase activity
D9783_RS14850	COG1674	ftsk spoiiie
D9783_RS14850	COG4980	gas vesicle protein
D9783_RS14855	COG2188	Transcriptional regulator
D9783_RS14860	COG1744	ABC transporter substrate-binding protein PnrA-like
D9783_RS14865	COG3845	ABC transporter
D9783_RS14870	COG4603	Belongs to the binding-protein-dependent transport system permease family
D9783_RS14875	COG1079	Belongs to the binding-protein-dependent transport system permease family
D9783_RS14880	COG0612	Peptidase, M16
D9783_RS14885	COG0612	Peptidase, M16
D9783_RS14890	COG0300	oxidoreductase activity
D9783_RS14905	COG1426	Protein conserved in bacteria
D9783_RS14910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D9783_RS14915	COG1546	Belongs to the CinA family
D9783_RS14915	COG1058	Belongs to the CinA family
D9783_RS14930	COG1960	acyl-CoA dehydrogenase activity
D9783_RS14935	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS14940	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS14945	COG1309	transcriptional regulator
D9783_RS14950	COG1250	3-hydroxyacyl-CoA dehydrogenase
D9783_RS14955	COG1024	Enoyl-CoA hydratase
D9783_RS14975	COG1960	acyl-CoA dehydrogenase activity
D9783_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS14985	COG1024	Enoyl-CoA hydratase
D9783_RS14995	COG0697	spore germination
D9783_RS15015	COG1692	metallophosphoesterase
D9783_RS15020	COG2359	stage V sporulation protein S
D9783_RS15030	COG0674	pyruvate-flavodoxin oxidoreductase activity
D9783_RS15030	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
D9783_RS15035	COG1013	pyruvate-flavodoxin oxidoreductase activity
D9783_RS15055	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D9783_RS15065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9783_RS15070	COG4550	Control of competence regulator ComK, YlbF/YmcA
D9783_RS15085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9783_RS15100	COG0551	DNA topoisomerase type I activity
D9783_RS15100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9783_RS15160	COG0739	heme binding
D9783_RS15175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D9783_RS15180	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D9783_RS15205	COG3546	catalase activity
D9783_RS15210	COG1113	amino acid transport
D9783_RS15220	COG1280	lysine exporter protein (LysE YggA)
D9783_RS15245	COG0277	FAD linked oxidase domain protein
D9783_RS15250	COG2271	Major facilitator Superfamily
D9783_RS15265	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D9783_RS15270	COG1923	regulation of RNA biosynthetic process
D9783_RS15280	COG0464	growth
D9783_RS15355	COG2860	membrane
D9783_RS15360	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D9783_RS15365	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
D9783_RS15370	COG0488	(ABC) transporter
D9783_RS15375	COG0789	Transcriptional regulator
D9783_RS15380	COG0174	glutamine synthetase
D9783_RS15385	COG1408	metallophosphoesterase
D9783_RS15395	COG3420	alginic acid biosynthetic process
D9783_RS15410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9783_RS15415	COG2169	Transcriptional regulator
D9783_RS15415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D9783_RS15450	COG0656	L-ascorbic acid biosynthetic process
D9783_RS15475	COG0305	Participates in initiation and elongation during chromosome replication
D9783_RS15525	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D9783_RS15535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9783_RS15575	COG1335	isochorismatase
D9783_RS15670	COG2746	aminoglycoside 3-N-acetyltransferase activity
D9783_RS15685	COG0546	phosphoglycolate phosphatase activity
D9783_RS15695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D9783_RS15730	COG2267	carboxylic ester hydrolase activity
D9783_RS15815	COG0640	Transcriptional regulator
D9783_RS15895	COG1595	DNA-templated transcription, initiation
D9783_RS15975	COG0768	penicillin binding
D9783_RS15980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D9783_RS16030	COG1695	Transcriptional regulator
D9783_RS16055	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
D9783_RS16065	COG3300	MHYT domain
D9783_RS16065	COG5001	Diguanylate cyclase
D9783_RS16070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D9783_RS16075	COG1388	LysM domain
D9783_RS16080	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D9783_RS16105	COG3763	UPF0154 protein
D9783_RS16115	COG1132	(ABC) transporter
D9783_RS16120	COG1132	(ABC) transporter
D9783_RS16130	COG0785	Cytochrome C biogenesis protein
D9783_RS16135	COG2201	protein-glutamate methylesterase activity
D9783_RS16140	COG4846	Membrane protein involved in cytochrome C biogenesis
D9783_RS16150	COG3852	Histidine kinase
D9783_RS16160	COG0420	3'-5' exonuclease activity
D9783_RS16165	COG0419	ATPase involved in DNA repair
D9783_RS16175	COG5146	pantothenate kinase activity
D9783_RS16180	COG1999	signal sequence binding
D9783_RS16185	COG1247	-acetyltransferase
D9783_RS16200	COG2514	catechol 2,3-dioxygenase activity
D9783_RS16205	COG0542	response to heat
D9783_RS16210	COG2861	carbohydrate metabolic process
D9783_RS16215	COG0456	acetyltransferase
D9783_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS16235	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9783_RS16240	COG0006	proline dipeptidase activity
D9783_RS16260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D9783_RS16270	COG1346	cytolysis
D9783_RS16275	COG0024	Methionine aminopeptidase
D9783_RS16280	COG3584	3D domain protein
D9783_RS16280	COG1388	LysM domain
D9783_RS16285	COG1929	Belongs to the glycerate kinase type-1 family
D9783_RS16290	COG0456	acetyltransferase
D9783_RS16295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9783_RS16325	COG1131	(ABC) transporter
D9783_RS16330	COG0842	Transport permease protein
D9783_RS16335	COG4585	Histidine kinase
D9783_RS16340	COG2197	response regulator
D9783_RS16350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D9783_RS16355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS16375	COG0824	Thioesterase
D9783_RS16390	COG0745	RESPONSE REGULATOR receiver
D9783_RS16395	COG5002	protein histidine kinase activity
D9783_RS16400	COG4841	protein insertion into membrane
D9783_RS16415	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D9783_RS16425	COG1125	glycine betaine transport
D9783_RS16425	COG0517	IMP dehydrogenase activity
D9783_RS16435	COG1732	Glycine betaine
D9783_RS16440	COG1832	CoA-binding protein
D9783_RS16445	COG0187	DNA topoisomerase II activity
D9783_RS16450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D9783_RS16470	COG2357	RelA SpoT domain protein
D9783_RS16480	COG0628	permease
D9783_RS16485	COG0477	Major facilitator Superfamily
D9783_RS16490	COG1309	transcriptional regulator
D9783_RS16495	COG1404	Belongs to the peptidase S8 family
D9783_RS16500	COG3693	PFAM glycoside hydrolase, family 10
D9783_RS16505	COG1027	Aspartate ammonia-lyase
D9783_RS16515	COG0745	RESPONSE REGULATOR receiver
D9783_RS16545	COG0436	Aminotransferase
D9783_RS16575	COG0493	'glutamate synthase
D9783_RS16580	COG0069	glutamate synthase activity
D9783_RS16580	COG0070	glutamate synthase
D9783_RS16580	COG0067	glutamate synthase
D9783_RS16585	COG0583	DNA-binding transcription factor activity
D9783_RS16600	COG2197	response regulator
D9783_RS16605	COG2201	protein-glutamate methylesterase activity
D9783_RS16610	COG2208	phosphoserine phosphatase activity
D9783_RS16620	COG2201	protein-glutamate methylesterase activity
D9783_RS16625	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9783_RS16635	COG2198	Histidine kinase
D9783_RS16635	COG0643	Histidine kinase
D9783_RS16640	COG0835	chemotaxis
D9783_RS16645	COG1492	cobalamin metabolic process
D9783_RS16660	COG2814	Major facilitator Superfamily
D9783_RS16680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9783_RS16685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D9783_RS16690	COG0697	spore germination
D9783_RS16695	COG4191	Histidine kinase
D9783_RS16715	COG0708	Exodeoxyribonuclease III
D9783_RS16740	COG0287	Prephenate dehydrogenase
D9783_RS16750	COG0456	acetyltransferase
D9783_RS16760	COG1388	LysM domain
D9783_RS16760	COG0791	NLP P60 protein
D9783_RS16765	COG0657	acetylesterase activity
D9783_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS16785	COG1960	acyl-CoA dehydrogenase activity
D9783_RS16790	COG0183	Belongs to the thiolase family
D9783_RS16795	COG1960	acyl-CoA dehydrogenase activity
D9783_RS16800	COG0183	Belongs to the thiolase family
D9783_RS16815	COG0410	ABC transporter
D9783_RS16825	COG1172	Belongs to the binding-protein-dependent transport system permease family
D9783_RS16830	COG0559	Belongs to the binding-protein-dependent transport system permease family
D9783_RS16835	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS16855	COG2340	Cysteine-rich secretory protein family
D9783_RS16865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D9783_RS16885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9783_RS16890	COG1011	Hydrolase
D9783_RS16900	COG2267	carboxylic ester hydrolase activity
D9783_RS16925	COG2340	Cysteine-rich secretory protein family
D9783_RS16940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D9783_RS16955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9783_RS16965	COG1999	signal sequence binding
D9783_RS16985	COG2720	vancomycin resistance protein
D9783_RS16995	COG1253	flavin adenine dinucleotide binding
D9783_RS17000	COG0697	spore germination
D9783_RS17005	COG0460	homoserine dehydrogenase
D9783_RS17010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D9783_RS17015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D9783_RS17025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D9783_RS17030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D9783_RS17035	COG2873	o-acetylhomoserine
D9783_RS17050	COG2084	Dehydrogenase
D9783_RS17060	COG2368	4-hydroxyphenylacetate
D9783_RS17070	COG4086	secreted protein
D9783_RS17085	COG0604	alcohol dehydrogenase
D9783_RS17100	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D9783_RS17105	COG2323	membrane
D9783_RS17115	COG1309	transcriptional regulator
D9783_RS17120	COG2814	Major facilitator Superfamily
D9783_RS17135	COG2176	DNA-directed DNA polymerase activity
D9783_RS17140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D9783_RS17145	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D9783_RS17170	COG2096	Adenosyltransferase
D9783_RS17185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D9783_RS17200	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
D9783_RS17205	COG1120	ATPase activity
D9783_RS17210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D9783_RS17215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D9783_RS17230	COG1695	Transcriptional regulator
D9783_RS17240	COG2226	methyltransferase
D9783_RS17245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9783_RS17260	COG0463	Glycosyl transferase, family 2
D9783_RS17275	COG1280	lysine exporter protein (LysE YggA)
D9783_RS17290	COG2996	Protein conserved in bacteria
D9783_RS17295	COG2223	nitrite transmembrane transporter activity
D9783_RS17305	COG1193	negative regulation of DNA recombination
D9783_RS17320	COG0488	(ABC) transporter
D9783_RS17325	COG0514	ATP-dependent DNA helicase (RecQ)
D9783_RS17350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9783_RS17355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D9783_RS17360	COG1686	Belongs to the peptidase S11 family
D9783_RS17370	COG3853	Toxic anion resistance protein (TelA)
D9783_RS17375	COG4548	von Willebrand factor, type A
D9783_RS17380	COG0714	Associated with various cellular activities
D9783_RS17390	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
D9783_RS17400	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
D9783_RS17400	COG2105	PFAM AIG2 family protein
D9783_RS17405	COG0668	transmembrane transport
D9783_RS17410	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS17430	COG2746	aminoglycoside 3-N-acetyltransferase activity
D9783_RS17440	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9783_RS17445	COG0567	Dehydrogenase, E1 component
D9783_RS17460	COG2814	Major facilitator Superfamily
D9783_RS17465	COG0840	transmembrane signaling receptor activity
D9783_RS17475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D9783_RS17480	COG1984	allophanate hydrolase subunit 2
D9783_RS17485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D9783_RS17495	COG2404	hydrolase activity, acting on ester bonds
D9783_RS17510	COG3011	Protein conserved in bacteria
D9783_RS17515	COG1063	alcohol dehydrogenase
D9783_RS17520	COG0406	alpha-ribazole phosphatase activity
D9783_RS17530	COG1595	DNA-templated transcription, initiation
D9783_RS17545	COG5001	Diguanylate cyclase
D9783_RS17560	COG2211	Major facilitator Superfamily
D9783_RS17565	COG1794	racemase activity, acting on amino acids and derivatives
D9783_RS17605	COG0640	Transcriptional regulator
D9783_RS17610	COG3048	D-serine ammonia-lyase activity
D9783_RS17615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9783_RS17615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D9783_RS17620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9783_RS17620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9783_RS17635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D9783_RS17640	COG0604	alcohol dehydrogenase
D9783_RS17640	COG3321	synthase
D9783_RS17655	COG2323	membrane
D9783_RS17685	COG0840	transmembrane signaling receptor activity
D9783_RS17700	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D9783_RS17705	COG4974	Belongs to the 'phage' integrase family
D9783_RS17845	COG2202	Pas domain
D9783_RS17845	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS17880	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D9783_RS17890	COG2318	DinB family
D9783_RS17905	COG0592	DNA-directed DNA polymerase activity
D9783_RS17915	COG1132	(ABC) transporter
D9783_RS17925	COG3300	MHYT domain
D9783_RS17925	COG5001	Diguanylate cyclase
D9783_RS17930	COG0596	Alpha beta hydrolase
D9783_RS17955	COG1595	DNA-templated transcription, initiation
D9783_RS17960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS17980	COG1408	metallophosphoesterase
D9783_RS17990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS18005	COG0768	penicillin binding
D9783_RS18045	COG1309	transcriptional regulator
D9783_RS18050	COG0477	Major facilitator Superfamily
D9783_RS18080	COG0346	lactoylglutathione lyase activity
D9783_RS18100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D9783_RS18125	COG1238	metal cluster binding
D9783_RS18165	COG1192	Involved in chromosome partitioning
D9783_RS18170	COG2385	sporulation resulting in formation of a cellular spore
D9783_RS18170	COG2247	cell wall binding repeat
D9783_RS18180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D9783_RS18190	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
D9783_RS18210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9783_RS18215	COG3226	Transcriptional regulator
D9783_RS18235	COG1115	amino acid carrier protein
D9783_RS18275	COG1830	Aldolase
D9783_RS18310	COG2323	membrane
D9783_RS18325	COG0840	transmembrane signaling receptor activity
D9783_RS18325	COG3290	protein histidine kinase activity
D9783_RS18365	COG2205	protein histidine kinase activity
D9783_RS18380	COG3541	Predicted nucleotidyltransferase
D9783_RS18385	COG0697	spore germination
D9783_RS18415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS18460	COG3708	Transcriptional regulator
D9783_RS18460	COG2207	Transcriptional regulator
D9783_RS18465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9783_RS18475	COG1183	phosphatidylcholine synthase activity
D9783_RS18485	COG3706	GGDEF domain
D9783_RS18490	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9783_RS18495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D9783_RS18500	COG4191	Histidine kinase
D9783_RS18520	COG5522	Integral membrane protein (intg_mem_TP0381)
D9783_RS18530	COG0165	Argininosuccinate lyase
D9783_RS18535	COG0137	argininosuccinate synthase activity
D9783_RS18540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D9783_RS18545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D9783_RS18550	COG0505	Belongs to the CarA family
D9783_RS18555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D9783_RS18560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D9783_RS18565	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D9783_RS18570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D9783_RS18575	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9783_RS18585	COG3264	Mechanosensitive ion channel
D9783_RS18585	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D9783_RS18600	COG3340	Belongs to the peptidase S51 family
D9783_RS18615	COG0697	spore germination
D9783_RS18620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D9783_RS18625	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS18630	COG0488	(ABC) transporter
D9783_RS18635	COG1278	Cold shock
D9783_RS18655	COG1366	Belongs to the anti-sigma-factor antagonist family
D9783_RS18685	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS18695	COG0372	Belongs to the citrate synthase family
D9783_RS18700	COG0583	DNA-binding transcription factor activity
D9783_RS18720	COG5578	integral membrane protein
D9783_RS18725	COG0697	spore germination
D9783_RS18730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9783_RS18735	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9783_RS18740	COG1607	acyl-coa hydrolase
D9783_RS18790	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D9783_RS18800	COG1253	flavin adenine dinucleotide binding
D9783_RS18805	COG2116	formate transmembrane transporter activity
D9783_RS18810	COG0730	response to heat
D9783_RS18815	COG0425	Belongs to the sulfur carrier protein TusA family
D9783_RS18820	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9783_RS18820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS18825	COG0425	Belongs to the sulfur carrier protein TusA family
D9783_RS18825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9783_RS18835	COG2210	Belongs to the sulfur carrier protein TusA family
D9783_RS18840	COG1937	Protein conserved in bacteria
D9783_RS18845	COG3300	MHYT domain
D9783_RS18845	COG5001	Diguanylate cyclase
D9783_RS18855	COG0326	Molecular chaperone. Has ATPase activity
D9783_RS18865	COG0531	amino acid
D9783_RS18875	COG0596	Alpha beta hydrolase
D9783_RS18900	COG2226	methyltransferase
D9783_RS18930	COG0346	lactoylglutathione lyase activity
D9783_RS18935	COG0640	Transcriptional regulator
D9783_RS18945	COG1051	belongs to the nudix hydrolase family
D9783_RS18955	COG1011	Hydrolase
D9783_RS18995	COG0596	Alpha beta hydrolase
D9783_RS19035	COG1960	acyl-CoA dehydrogenase activity
D9783_RS19040	COG0789	Transcriptional regulator
D9783_RS19050	COG3852	Histidine kinase
D9783_RS19060	COG2226	methyltransferase
D9783_RS19085	COG0456	acetyltransferase
D9783_RS19095	COG0701	Predicted permease
D9783_RS19125	COG0134	indole-3-glycerol-phosphate synthase activity
D9783_RS19130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9783_RS19135	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D9783_RS19135	COG0512	Glutamine amidotransferase of anthranilate synthase
D9783_RS19140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D9783_RS19150	COG1233	COG1233 Phytoene dehydrogenase and related
D9783_RS19160	COG0454	-acetyltransferase
D9783_RS19160	COG0456	acetyltransferase
D9783_RS19175	COG0352	thiamine-phosphate diphosphorylase activity
D9783_RS19180	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D9783_RS19185	COG0351	phosphomethylpyrimidine kinase
D9783_RS19185	COG0352	thiamine-phosphate diphosphorylase activity
D9783_RS19195	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
D9783_RS19200	COG1793	dna ligase
D9783_RS19200	COG3285	dna ligase
D9783_RS19210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D9783_RS19215	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D9783_RS19220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
D9783_RS19225	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9783_RS19225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D9783_RS19230	COG0307	riboflavin synthase, alpha
D9783_RS19250	COG4667	esterase of the alpha-beta hydrolase superfamily
D9783_RS19255	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9783_RS19260	COG1131	(ABC) transporter
D9783_RS19280	COG0586	Pfam SNARE associated Golgi protein
D9783_RS19285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D9783_RS19295	COG1268	BioY protein
D9783_RS19300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D9783_RS19305	COG2814	Major facilitator Superfamily
D9783_RS19310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9783_RS19320	COG0463	Glycosyl transferase, family 2
D9783_RS19320	COG1216	Glycosyl transferase, family 2
D9783_RS19335	COG0534	Mate efflux family protein
D9783_RS19355	COG0477	Major facilitator Superfamily
D9783_RS19360	COG1846	Transcriptional regulator
D9783_RS19365	COG0523	cobalamin synthesis protein
D9783_RS19375	COG0793	Belongs to the peptidase S41A family
D9783_RS19375	COG3409	Peptidoglycan-binding domain 1 protein
D9783_RS19380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS19385	COG1876	peptidase activity
D9783_RS19400	COG4326	sporulation control protein
D9783_RS19425	COG4479	Belongs to the UPF0346 family
D9783_RS19430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D9783_RS19435	COG0840	transmembrane signaling receptor activity
D9783_RS19460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D9783_RS19480	COG2190	(PTS) system
D9783_RS19485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9783_RS19490	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D9783_RS19510	COG2755	lipolytic protein G-D-S-L family
D9783_RS19520	COG1307	EDD domain protein, DegV family
D9783_RS19530	COG2135	peptidase activity
D9783_RS19540	COG1272	protein, Hemolysin III
D9783_RS19550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D9783_RS19555	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D9783_RS19570	COG2521	methyltransferase
D9783_RS19570	COG2136	Putative SAM-dependent methyltransferase
D9783_RS19580	COG1413	lyase activity
D9783_RS19585	COG0488	(ABC) transporter
D9783_RS19590	COG1418	mRNA catabolic process
D9783_RS19595	COG1307	EDD domain protein, DegV family
D9783_RS19610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9783_RS19615	COG1988	membrane-bound metal-dependent
D9783_RS19635	COG1321	iron dependent repressor
D9783_RS19640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9783_RS19645	COG1321	iron dependent repressor
D9783_RS19645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9783_RS19650	COG1121	(ABC) transporter
D9783_RS19655	COG0803	Belongs to the bacterial solute-binding protein 9 family
D9783_RS19660	COG1278	Cold shock
D9783_RS19670	COG0328	RNA-DNA hybrid ribonuclease activity
D9783_RS19675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D9783_RS19680	COG0328	RNA-DNA hybrid ribonuclease activity
D9783_RS19705	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9783_RS19720	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9783_RS19730	COG1755	Isoprenylcysteine carboxyl methyltransferase
D9783_RS19735	COG3424	synthase
D9783_RS19745	COG1028	Short-chain dehydrogenase reductase Sdr
D9783_RS19765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D9783_RS19770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D9783_RS19775	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D9783_RS19780	COG1199	ATP-dependent helicase activity
D9783_RS19785	COG0116	Belongs to the methyltransferase superfamily
D9783_RS19795	COG3599	regulation of cell shape
D9783_RS19810	COG3359	exonuclease
D9783_RS19815	COG1111	helicase
D9783_RS19815	COG1205	dead DEAH box helicase
D9783_RS19885	COG4499	WXG100 protein secretion system (Wss), protein YukC
D9783_RS19885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D9783_RS19895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D9783_RS19900	COG3935	DnaD domain protein
D9783_RS19905	COG0017	Asparaginyl-tRNA synthetase
D9783_RS19910	COG0436	Aminotransferase
D9783_RS19930	COG1199	ATP-dependent helicase activity
D9783_RS19930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D9783_RS19935	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
D9783_RS19940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D9783_RS19955	COG0617	tRNA 3'-terminal CCA addition
D9783_RS19960	COG0438	transferase activity, transferring glycosyl groups
D9783_RS19965	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
D9783_RS19970	COG1803	Methylglyoxal synthase
D9783_RS19975	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D9783_RS19980	COG1694	Mazg nucleotide pyrophosphohydrolase
D9783_RS19985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS19990	COG2738	Putative neutral zinc metallopeptidase
D9783_RS20000	COG4347	Protein of unknown function (DUF1405)
D9783_RS20010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D9783_RS20030	COG0457	Tetratricopeptide repeat
D9783_RS20040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D9783_RS20045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D9783_RS20050	COG4401	Chorismate mutase type I
D9783_RS20055	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D9783_RS20060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D9783_RS20065	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D9783_RS20070	COG0105	UTP biosynthetic process
D9783_RS20075	COG0142	geranyltranstransferase activity
D9783_RS20080	COG2226	methyltransferase
D9783_RS20085	COG0142	geranyltranstransferase activity
D9783_RS20095	COG0302	gtp cyclohydrolase
D9783_RS20100	COG0776	regulation of translation
D9783_RS20105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
D9783_RS20125	COG1160	GTP binding
D9783_RS20150	COG1304	FMN binding
D9783_RS20155	COG0539	negative regulation of cytoplasmic translation
D9783_RS20160	COG0204	Acyl-transferase
D9783_RS20165	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D9783_RS20180	COG2959	enzyme of heme biosynthesis
D9783_RS20185	COG3773	Cell wall hydrolase
D9783_RS20185	COG3409	Peptidoglycan-binding domain 1 protein
D9783_RS20190	COG2339	peptidase activity
D9783_RS20195	COG0252	asparaginase activity
D9783_RS20200	COG0492	ferredoxin-NADP+ reductase activity
D9783_RS20205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9783_RS20210	COG4862	establishment of competence for transformation
D9783_RS20220	COG1408	metallophosphoesterase
D9783_RS20245	COG3546	catalase activity
D9783_RS20255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D9783_RS20255	COG0438	transferase activity, transferring glycosyl groups
D9783_RS20260	COG0671	phosphoesterase, PA-phosphatase related
D9783_RS20275	COG0514	ATP-dependent DNA helicase (RecQ)
D9783_RS20285	COG1141	Ferredoxin
D9783_RS20290	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D9783_RS20295	COG0741	lytic transglycosylase activity
D9783_RS20295	COG0739	heme binding
D9783_RS20295	COG1196	nuclear chromosome segregation
D9783_RS20305	COG1595	DNA-templated transcription, initiation
D9783_RS20310	COG5002	protein histidine kinase activity
D9783_RS20315	COG0745	RESPONSE REGULATOR receiver
D9783_RS20320	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9783_RS20325	COG1333	cytochrome c biogenesis protein
D9783_RS20330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D9783_RS20335	COG1187	pseudouridine synthase activity
D9783_RS20340	COG0700	Nucleoside recognition
D9783_RS20345	COG2715	membrane protein required for spore maturation
D9783_RS20350	COG1686	Belongs to the peptidase S11 family
D9783_RS20360	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D9783_RS20365	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D9783_RS20370	COG1547	Domain of unknown function (DUF309)
D9783_RS20385	COG0697	spore germination
D9783_RS20410	COG2172	sigma factor antagonist activity
D9783_RS20420	COG1686	Belongs to the peptidase S11 family
D9783_RS20435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D9783_RS20440	COG4974	Belongs to the 'phage' integrase family
D9783_RS20450	COG0735	belongs to the Fur family
D9783_RS20455	COG1300	Membrane
D9783_RS20460	COG1379	DNA repair
D9783_RS20475	COG0667	Aldo Keto reductase
D9783_RS20480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D9783_RS20480	COG0456	acetyltransferase
D9783_RS20495	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D9783_RS20500	COG0183	Belongs to the thiolase family
D9783_RS20505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D9783_RS20510	COG1073	alpha beta
D9783_RS20515	COG4918	Iron-sulphur cluster biosynthesis
D9783_RS20530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9783_RS20545	COG0535	radical SAM domain protein
D9783_RS20555	COG1595	DNA-templated transcription, initiation
D9783_RS20560	COG0300	oxidoreductase activity
D9783_RS20565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS20575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9783_RS20580	COG1215	transferase activity, transferring glycosyl groups
D9783_RS20585	COG1902	pentaerythritol trinitrate reductase activity
D9783_RS20595	COG1234	tRNA 3'-trailer cleavage
D9783_RS20600	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D9783_RS20605	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
D9783_RS20610	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D9783_RS20615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D9783_RS20625	COG2195	Cleaves the N-terminal amino acid of tripeptides
D9783_RS20630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D9783_RS20635	COG0346	lactoylglutathione lyase activity
D9783_RS20640	COG1376	ErfK ybiS ycfS ynhG family protein
D9783_RS20645	COG4129	membrane
D9783_RS20650	COG1126	abc transporter atp-binding protein
D9783_RS20655	COG0765	amino acid transport
D9783_RS20660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9783_RS20675	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9783_RS20675	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9783_RS20680	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
D9783_RS20685	COG0508	dehydrogenase complex catalyzes the overall conversion of
D9783_RS20690	COG0022	dehydrogenase e1 component
D9783_RS20695	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D9783_RS20700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D9783_RS20705	COG3426	butyrate kinase activity
D9783_RS20715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D9783_RS20720	COG0280	phosphate acetyltransferase
D9783_RS20725	COG3290	protein histidine kinase activity
D9783_RS20725	COG3829	transcription factor binding
D9783_RS20735	COG0584	glycerophosphoryl diester phosphodiesterase
D9783_RS20750	COG0750	zinc metalloprotease
D9783_RS20755	COG0497	DNA recombination
D9783_RS20765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D9783_RS20770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D9783_RS20785	COG1722	exodeoxyribonuclease VII activity
D9783_RS20795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D9783_RS20805	COG1302	Protein conserved in bacteria
D9783_RS20810	COG0439	Biotin carboxylase
D9783_RS20815	COG0511	ligase activity, forming carbon-carbon bonds
D9783_RS20860	COG3854	ATPases associated with a variety of cellular activities
D9783_RS20865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D9783_RS20870	COG0006	proline dipeptidase activity
D9783_RS20890	COG1752	Esterase of the alpha-beta hydrolase superfamily
D9783_RS20895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D9783_RS20905	COG0095	Lipoate-protein ligase
D9783_RS20910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D9783_RS20925	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9783_RS20930	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D9783_RS20935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D9783_RS20940	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D9783_RS20955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D9783_RS20980	COG4537	Required for transformation and DNA binding
D9783_RS20985	COG1459	type II secretion system
D9783_RS20990	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9783_RS21000	COG1393	Belongs to the ArsC family
D9783_RS21010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D9783_RS21020	COG0011	TIGRFAM Protein of
D9783_RS21035	COG1368	sulfuric ester hydrolase activity
D9783_RS21040	COG1940	carbohydrate kinase activity
D9783_RS21050	COG0697	spore germination
D9783_RS21060	COG0457	Tetratricopeptide repeat
D9783_RS21060	COG0705	Rhomboid family
D9783_RS21070	COG1836	PFAM Integral membrane protein DUF92
D9783_RS21075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D9783_RS21090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D9783_RS21115	COG0704	Plays a role in the regulation of phosphate uptake
D9783_RS21120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D9783_RS21125	COG0581	inorganic phosphate transmembrane transporter activity
D9783_RS21130	COG0573	inorganic phosphate transmembrane transporter activity
D9783_RS21135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D9783_RS21140	COG0768	penicillin binding
D9783_RS21145	COG0477	Major facilitator Superfamily
D9783_RS21155	COG2839	Protein conserved in bacteria
D9783_RS21160	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9783_RS21165	COG5521	maltodextrose utilization protein MalA
D9783_RS21180	COG4709	membrane
D9783_RS21185	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
D9783_RS21190	COG0735	belongs to the Fur family
D9783_RS21195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D9783_RS21200	COG1121	(ABC) transporter
D9783_RS21205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D9783_RS21215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D9783_RS21220	COG0513	Belongs to the DEAD box helicase family
D9783_RS21230	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D9783_RS21235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D9783_RS21240	COG2384	SAM-dependent methyltransferase
D9783_RS21245	COG2010	Cytochrome c
D9783_RS21250	COG1960	acyl-CoA dehydrogenase activity
D9783_RS21260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D9783_RS21265	COG0358	DNA primase activity
D9783_RS21270	COG1671	Belongs to the UPF0178 family
D9783_RS21275	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D9783_RS21280	COG0517	IMP dehydrogenase activity
D9783_RS21290	COG1381	Involved in DNA repair and RecF pathway recombination
D9783_RS21300	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D9783_RS21305	COG0295	cytidine deaminase activity
D9783_RS21310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D9783_RS21320	COG1480	7TM receptor with intracellular HD hydrolase
D9783_RS21325	COG1702	phosphate starvation-inducible protein PhoH
D9783_RS21350	COG1030	water channel activity
D9783_RS21355	COG1610	YqeY-like protein
D9783_RS21360	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D9783_RS21365	COG1283	sodium-dependent phosphate transmembrane transporter activity
D9783_RS21370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D9783_RS21375	COG0366	Alpha amylase catalytic
D9783_RS21380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D9783_RS21385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D9783_RS21400	COG0443	Heat shock 70 kDa protein
D9783_RS21405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D9783_RS21410	COG1420	regulation of RNA biosynthetic process
D9783_RS21415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D9783_RS21420	COG0481	GTPase activity
D9783_RS21430	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9783_RS21445	COG1466	dna polymerase III delta subunit
D9783_RS21455	COG0658	competence protein
D9783_RS21455	COG2333	competence protein COMEC
D9783_RS21460	COG2131	deaminase
D9783_RS21470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D9783_RS21475	COG2226	methyltransferase
D9783_RS21480	COG0799	negative regulation of ribosome biogenesis
D9783_RS21485	COG1713	HD superfamily hydrolase involved in NAD metabolism
D9783_RS21490	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D9783_RS21495	COG1534	Rna-binding protein
D9783_RS21505	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D9783_RS21510	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D9783_RS21520	COG0688	phosphatidylethanolamine metabolic process
D9783_RS21530	COG0783	Belongs to the Dps family
D9783_RS21565	COG0626	cystathionine gamma-synthase activity
D9783_RS21570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D9783_RS21575	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D9783_RS21580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D9783_RS21590	COG2226	methyltransferase
D9783_RS21605	COG0768	penicillin binding
D9783_RS21615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D9783_RS21620	COG0572	uridine kinase
D9783_RS21625	COG0826	peptidase U32
D9783_RS21630	COG0826	peptidase U32
D9783_RS21635	COG4122	O-methyltransferase activity
D9783_RS21640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D9783_RS21645	COG3906	Belongs to the UPF0473 family
D9783_RS21650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D9783_RS21655	COG4472	Bacterial protein of unknown function (DUF965)
D9783_RS21660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D9783_RS21665	COG0628	permease
D9783_RS21680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D9783_RS21690	COG0482	sulfurtransferase activity
D9783_RS21695	COG1104	cysteine desulfurase activity
D9783_RS21700	COG1959	2 iron, 2 sulfur cluster binding
D9783_RS21705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D9783_RS21710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
D9783_RS21715	COG1131	(ABC) transporter
D9783_RS21720	COG1131	(ABC) transporter
D9783_RS21725	COG1725	Transcriptional regulator
D9783_RS21740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D9783_RS21750	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D9783_RS21755	COG0124	histidyl-tRNA synthetase
D9783_RS21765	COG3103	Sh3 type 3 domain protein
D9783_RS21765	COG0860	N-Acetylmuramoyl-L-alanine amidase
D9783_RS21765	COG4991	sh3 domain protein
D9783_RS21770	COG1490	D-aminoacyl-tRNA deacylase activity
D9783_RS21775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D9783_RS21780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D9783_RS21785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D9783_RS21785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D9783_RS21790	COG5416	Lipopolysaccharide assembly protein A domain
D9783_RS21795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D9783_RS21800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9783_RS21800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D9783_RS21810	COG2244	polysaccharide biosynthetic process
D9783_RS21815	COG2323	membrane
D9783_RS21830	COG1862	Preprotein translocase
D9783_RS21840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D9783_RS21855	COG0632	four-way junction helicase activity
D9783_RS21875	COG1388	LysM domain
D9783_RS21885	COG0157	Belongs to the NadC ModD family
D9783_RS21890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D9783_RS21895	COG1104	cysteine desulfurase activity
D9783_RS21900	COG1827	regulation of RNA biosynthetic process
D9783_RS21905	COG0077	Prephenate dehydratase
D9783_RS21910	COG4492	Belongs to the UPF0735 family
D9783_RS21915	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D9783_RS21920	COG3290	protein histidine kinase activity
D9783_RS21925	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D9783_RS21930	COG2868	ribosomal protein
D9783_RS21935	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D9783_RS21940	COG1530	ribonuclease E activity
D9783_RS21945	COG1994	Peptidase M50
D9783_RS21950	COG0739	heme binding
D9783_RS21955	COG2894	cell division
D9783_RS21960	COG0850	regulation of cytokinetic process
D9783_RS21965	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D9783_RS21970	COG1792	Involved in formation and maintenance of cell shape
D9783_RS21975	COG1077	Cell shape determining protein MreB Mrl
D9783_RS21990	COG2003	Belongs to the UPF0758 family
D9783_RS21995	COG0424	maF-like protein
D9783_RS22020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
D9783_RS22030	COG1459	type II secretion system
D9783_RS22040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D9783_RS22085	COG3706	GGDEF domain
D9783_RS22090	COG0285	dihydrofolate synthase activity
D9783_RS22095	COG0525	valine-tRNA ligase activity
D9783_RS22110	COG1388	LysM domain
D9783_RS22110	COG1388	LysM domain
D9783_RS22115	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D9783_RS22120	COG0113	porphobilinogen synthase activity
D9783_RS22135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D9783_RS22150	COG1126	abc transporter atp-binding protein
D9783_RS22155	COG0765	amino acid transport
D9783_RS22160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D9783_RS22165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D9783_RS22170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D9783_RS22175	COG0470	DNA polymerase III
D9783_RS22175	COG1067	ATP-dependent peptidase activity
D9783_RS22185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D9783_RS22190	COG0544	peptidyl-prolyl cis-trans isomerase activity
D9783_RS22205	COG0622	Phosphoesterase
D9783_RS22220	COG5401	PFAM Sporulation and spore germination
D9783_RS22225	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D9783_RS22230	COG1846	Transcriptional regulator
D9783_RS22235	COG2197	response regulator
D9783_RS22240	COG0824	Thioesterase
D9783_RS22245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D9783_RS22250	COG1053	succinate dehydrogenase
D9783_RS22255	COG2009	succinate dehydrogenase
D9783_RS22260	COG1719	4-vinyl reductase, 4VR
D9783_RS22270	COG0322	excinuclease ABC activity
D9783_RS22275	COG3118	belongs to the thioredoxin family
D9783_RS22285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
D9783_RS22290	COG2086	electron transfer activity
D9783_RS22295	COG1024	Enoyl-CoA hydratase
D9783_RS22300	COG1309	transcriptional regulator
D9783_RS22305	COG0318	PFAM AMP-dependent synthetase and ligase
D9783_RS22310	COG0659	secondary active sulfate transmembrane transporter activity
D9783_RS22315	COG0861	Integral membrane protein TerC family
D9783_RS22335	COG3766	membrane
D9783_RS22345	COG1796	DNA polymerase
D9783_RS22345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D9783_RS22350	COG1286	toxin biosynthetic process
D9783_RS22355	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D9783_RS22360	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D9783_RS22375	COG0072	phenylalanine-tRNA ligase activity
D9783_RS22375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D9783_RS22380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D9783_RS22385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D9783_RS22395	COG1363	Peptidase, m42
D9783_RS22415	COG0398	Pfam SNARE associated Golgi protein
D9783_RS22420	COG3326	Membrane
D9783_RS22425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
D9783_RS22435	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
D9783_RS22450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D9783_RS22460	COG3611	Membrane attachment protein
D9783_RS22465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D9783_RS22475	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
D9783_RS22480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D9783_RS22490	COG1971	Probably functions as a manganese efflux pump
D9783_RS22495	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D9783_RS22500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9783_RS22500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D9783_RS22510	COG0330	HflC and HflK could
D9783_RS22515	COG5002	protein histidine kinase activity
D9783_RS22520	COG0745	RESPONSE REGULATOR receiver
D9783_RS22530	COG0039	L-malate dehydrogenase activity
D9783_RS22535	COG0538	isocitrate dehydrogenase activity
D9783_RS22540	COG0372	Belongs to the citrate synthase family
D9783_RS22545	COG0628	permease
D9783_RS22555	COG3030	protein affecting phage T7 exclusion by the F plasmid
D9783_RS22565	COG0205	6-phosphofructokinase activity
D9783_RS22570	COG0825	malonyl-CoA metabolic process