locus-tag	class	description
BUW91_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BUW91_RS00010	COG0592	DNA-directed DNA polymerase activity
BUW91_RS00015	COG2501	S4 domain
BUW91_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BUW91_RS00025	COG0187	DNA topoisomerase II activity
BUW91_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS00065	COG0516	GMP reductase activity
BUW91_RS00065	COG0517	IMP dehydrogenase activity
BUW91_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BUW91_RS00095	COG1428	Deoxynucleoside kinase
BUW91_RS00100	COG1428	Deoxynucleoside kinase
BUW91_RS00105	COG3858	chitin binding
BUW91_RS00105	COG1388	LysM domain
BUW91_RS00110	COG1335	isochorismatase
BUW91_RS00115	COG0590	tRNA wobble adenosine to inosine editing
BUW91_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUW91_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BUW91_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BUW91_RS00240	COG1982	Orn Lys Arg decarboxylase major
BUW91_RS00245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BUW91_RS00250	COG3870	Protein conserved in bacteria
BUW91_RS00255	COG0470	DNA polymerase III
BUW91_RS00260	COG1774	PSP1 C-terminal conserved region
BUW91_RS00265	COG4467	Involved in initiation control of chromosome replication
BUW91_RS00270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BUW91_RS00275	COG2827	Endonuclease containing a URI domain
BUW91_RS00280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BUW91_RS00285	COG2002	toxin-antitoxin pair type II binding
BUW91_RS00295	COG0084	hydrolase, TatD family'
BUW91_RS00305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BUW91_RS00315	COG4466	Protein conserved in bacteria
BUW91_RS00330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_RS00335	COG0251	oxidation-reduction process
BUW91_RS00340	COG2088	sporulation resulting in formation of a cellular spore
BUW91_RS00345	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BUW91_RS00355	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BUW91_RS00360	COG0193	aminoacyl-tRNA hydrolase activity
BUW91_RS00370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUW91_RS00380	COG2002	toxin-antitoxin pair type II binding
BUW91_RS00385	COG2244	polysaccharide biosynthetic process
BUW91_RS00390	COG3956	TIGRFAM MazG family protein
BUW91_RS00395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BUW91_RS00410	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BUW91_RS00415	COG1098	S1 RNA binding domain
BUW91_RS00435	COG2304	oxidoreductase activity
BUW91_RS00440	COG0515	serine threonine protein kinase
BUW91_RS00445	COG0037	tRNA processing
BUW91_RS00450	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BUW91_RS00455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUW91_RS00460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BUW91_RS00465	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BUW91_RS00470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_RS00475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BUW91_RS00480	COG0512	Glutamine amidotransferase of anthranilate synthase
BUW91_RS00485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS00490	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUW91_RS00495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BUW91_RS00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BUW91_RS00525	COG3880	PFAM UvrB UvrC protein
BUW91_RS00530	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BUW91_RS00535	COG0542	response to heat
BUW91_RS00540	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BUW91_RS00545	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BUW91_RS00550	COG4956	integral membrane protein (PIN domain superfamily)
BUW91_RS00555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BUW91_RS00570	COG1045	serine acetyltransferase
BUW91_RS00575	COG0215	cysteine-tRNA ligase activity
BUW91_RS00585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUW91_RS00590	COG3688	RNA-binding protein containing a PIN domain
BUW91_RS00600	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BUW91_RS00605	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUW91_RS00610	COG0250	Participates in transcription elongation, termination and antitermination
BUW91_RS00615	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BUW91_RS00620	COG0081	regulation of translation
BUW91_RS00625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BUW91_RS00630	COG0222	ribosome binding
BUW91_RS00635	COG2813	Specifically methylates the guanine in position
BUW91_RS00640	COG0085	RNA polymerase activity
BUW91_RS00650	COG1358	cellular component organization or biogenesis
BUW91_RS00655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BUW91_RS00660	COG0049	tRNA binding
BUW91_RS00670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BUW91_RS00675	COG0051	transcription antitermination factor activity, RNA binding
BUW91_RS00680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BUW91_RS00685	COG0088	Forms part of the polypeptide exit tunnel
BUW91_RS00690	COG0089	rRNA binding
BUW91_RS00695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BUW91_RS00700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BUW91_RS00705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BUW91_RS00715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BUW91_RS00720	COG0255	Belongs to the universal ribosomal protein uL29 family
BUW91_RS00725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BUW91_RS00730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BUW91_RS00745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BUW91_RS00760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BUW91_RS00765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BUW91_RS00770	COG1841	ribosomal large subunit assembly
BUW91_RS00780	COG0201	protein transport
BUW91_RS00785	COG0563	adenylate kinase activity
BUW91_RS00790	COG0024	Methionine aminopeptidase
BUW91_RS00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BUW91_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BUW91_RS00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BUW91_RS00815	COG0202	RNA polymerase activity
BUW91_RS00820	COG0203	ribosomal protein L17
BUW91_RS00825	COG1122	ATPase activity
BUW91_RS00830	COG1122	ATPase activity
BUW91_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BUW91_RS00840	COG0101	tRNA pseudouridine synthase activity
BUW91_RS00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BUW91_RS00860	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_RS00865	COG0489	protein tyrosine kinase activity
BUW91_RS00870	COG0583	DNA-binding transcription factor activity
BUW91_RS00880	COG2194	sulfuric ester hydrolase activity
BUW91_RS00885	COG0726	polysaccharide deacetylase
BUW91_RS00970	COG1595	DNA-templated transcription, initiation
BUW91_RS00975	COG5662	AntiSigma factor
BUW91_RS00980	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUW91_RS00990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_RS00995	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BUW91_RS01010	COG3103	Sh3 type 3 domain protein
BUW91_RS01010	COG1388	LysM domain
BUW91_RS01010	COG0791	NLP P60 protein
BUW91_RS01015	COG2213	PTS system mannitol-specific
BUW91_RS01015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS01020	COG3711	transcriptional antiterminator
BUW91_RS01025	COG0246	Mannitol dehydrogenase
BUW91_RS01035	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS01040	COG1970	mechanosensitive ion channel activity
BUW91_RS01045	COG1368	sulfuric ester hydrolase activity
BUW91_RS01065	COG1177	transmembrane transport
BUW91_RS01070	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BUW91_RS01080	COG0745	RESPONSE REGULATOR receiver
BUW91_RS01085	COG5002	protein histidine kinase activity
BUW91_RS01100	COG3976	FMN-binding domain protein
BUW91_RS01100	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BUW91_RS01105	COG1181	Belongs to the D-alanine--D-alanine ligase family
BUW91_RS01110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUW91_RS01115	COG0513	Belongs to the DEAD box helicase family
BUW91_RS01120	COG4294	response to UV
BUW91_RS01125	COG0705	Rhomboid family
BUW91_RS01130	COG0736	holo-[acyl-carrier-protein] synthase activity
BUW91_RS01135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BUW91_RS01140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BUW91_RS01145	COG0864	Transcriptional regulator
BUW91_RS01150	COG2337	Toxic component of a toxin-antitoxin (TA) module
BUW91_RS01155	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS01160	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS01165	COG2172	sigma factor antagonist activity
BUW91_RS01170	COG2208	phosphoserine phosphatase activity
BUW91_RS01175	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS01185	COG1191	sigma factor activity
BUW91_RS01190	COG2208	phosphoserine phosphatase activity
BUW91_RS01195	COG2183	response to ionizing radiation
BUW91_RS01285	COG0802	atpase or kinase
BUW91_RS01290	COG1214	PFAM Peptidase M22, glycoprotease
BUW91_RS01295	COG0456	acetyltransferase
BUW91_RS01305	COG0488	(ABC) transporter
BUW91_RS01310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BUW91_RS01315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_RS01320	COG0805	protein transport
BUW91_RS01330	COG1266	CAAX protease self-immunity
BUW91_RS01335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BUW91_RS01345	COG0714	Associated with various cellular activities
BUW91_RS01350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BUW91_RS01355	COG1305	Transglutaminase-like
BUW91_RS01360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BUW91_RS01360	COG0519	Catalyzes the synthesis of GMP from XMP
BUW91_RS01365	COG2252	PERMEase
BUW91_RS01420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BUW91_RS01425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BUW91_RS01430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BUW91_RS01435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BUW91_RS01440	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUW91_RS01445	COG0047	phosphoribosylformylglycinamidine synthase activity
BUW91_RS01450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BUW91_RS01455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BUW91_RS01460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BUW91_RS01465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BUW91_RS01470	COG0138	bifunctional purine biosynthesis protein purh
BUW91_RS01475	COG0151	Belongs to the GarS family
BUW91_RS01485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUW91_RS01490	COG4496	protein, YerC YecD
BUW91_RS01495	COG0423	glycine-tRNA ligase activity
BUW91_RS01505	COG0210	DNA helicase
BUW91_RS01515	COG4851	CamS sex pheromone cAM373 precursor
BUW91_RS01525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BUW91_RS01530	COG0154	amidase activity
BUW91_RS01540	COG1597	lipid kinase activity
BUW91_RS01550	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS01560	COG0166	Belongs to the GPI family
BUW91_RS01565	COG1744	ABC transporter substrate-binding protein PnrA-like
BUW91_RS01570	COG3852	Histidine kinase
BUW91_RS01575	COG0024	Methionine aminopeptidase
BUW91_RS01590	COG0789	Transcriptional regulator
BUW91_RS01590	COG4978	Transcriptional regulator
BUW91_RS01595	COG2814	Major facilitator Superfamily
BUW91_RS01605	COG1876	peptidase activity
BUW91_RS01610	COG1126	abc transporter atp-binding protein
BUW91_RS01615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS01620	COG0765	amino acid transport
BUW91_RS01625	COG0765	amino acid transport
BUW91_RS01635	COG2733	membrane
BUW91_RS01640	COG3212	peptidase
BUW91_RS01645	COG3212	peptidase
BUW91_RS01650	COG3850	Histidine kinase
BUW91_RS01650	COG5002	protein histidine kinase activity
BUW91_RS01655	COG0745	RESPONSE REGULATOR receiver
BUW91_RS01660	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS01665	COG1764	response to oxidative stress
BUW91_RS01670	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BUW91_RS01680	COG2259	Doxx family
BUW91_RS01685	COG0693	protein deglycase activity
BUW91_RS01695	COG2318	DinB family
BUW91_RS01705	COG1115	amino acid carrier protein
BUW91_RS01720	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BUW91_RS01725	COG0598	Magnesium transport protein CorA
BUW91_RS01730	COG3290	protein histidine kinase activity
BUW91_RS01735	COG4565	transcriptional regulatory protein
BUW91_RS01750	COG4191	Histidine kinase
BUW91_RS01755	COG0513	Belongs to the DEAD box helicase family
BUW91_RS01775	COG4842	Belongs to the WXG100 family
BUW91_RS01780	COG5417	Belongs to the EsaB family
BUW91_RS01785	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUW91_RS01810	COG2356	endonuclease I
BUW91_RS01820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_RS01835	COG0488	(ABC) transporter
BUW91_RS01840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_RS01845	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BUW91_RS01855	COG1959	2 iron, 2 sulfur cluster binding
BUW91_RS01860	COG1017	nitric oxide dioxygenase activity
BUW91_RS01860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BUW91_RS01870	COG0693	protein deglycase activity
BUW91_RS01875	COG2340	Cysteine-rich secretory protein family
BUW91_RS01880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BUW91_RS01885	COG4840	Belongs to the UPF0435 family
BUW91_RS01890	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BUW91_RS01895	COG4980	gas vesicle protein
BUW91_RS01900	COG1295	ribonuclease BN
BUW91_RS01905	COG2217	Heavy metal translocating P-type atpase
BUW91_RS01915	COG0640	Transcriptional regulator
BUW91_RS01925	COG0477	Major facilitator Superfamily
BUW91_RS01940	COG3871	stress protein (general stress protein 26)
BUW91_RS01945	COG0387	Pfam Sodium calcium exchanger
BUW91_RS01955	COG0535	radical SAM domain protein
BUW91_RS01975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUW91_RS01985	COG1113	amino acid transport
BUW91_RS02010	COG1090	epimerase
BUW91_RS02020	COG4221	oxidoreductase activity
BUW91_RS02040	COG1988	membrane-bound metal-dependent
BUW91_RS02045	COG1194	a g-specific adenine glycosylase
BUW91_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS02070	COG3557	Belongs to the UPF0374 family
BUW91_RS02075	COG1132	(ABC) transporter
BUW91_RS02080	COG4129	membrane
BUW91_RS02085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BUW91_RS02090	COG4555	ABC transporter
BUW91_RS02110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BUW91_RS02115	COG0735	belongs to the Fur family
BUW91_RS02215	COG3382	B3 4 domain protein
BUW91_RS02230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BUW91_RS02235	COG2766	serine protein kinase
BUW91_RS02250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_RS02265	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BUW91_RS02275	COG1968	undecaprenyl-diphosphatase activity
BUW91_RS02280	COG1301	dicarboxylic acid transport
BUW91_RS02285	COG0628	permease
BUW91_RS02290	COG0586	Pfam SNARE associated Golgi protein
BUW91_RS02295	COG2217	Heavy metal translocating P-type atpase
BUW91_RS02300	COG0531	amino acid
BUW91_RS02315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BUW91_RS02320	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUW91_RS02325	COG3842	ATPase activity
BUW91_RS02330	COG1175	transmembrane transport
BUW91_RS02345	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_RS02365	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_RS02410	COG3584	3D domain protein
BUW91_RS02410	COG3583	domain protein
BUW91_RS02415	COG1876	peptidase activity
BUW91_RS02425	COG3103	Sh3 type 3 domain protein
BUW91_RS02430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS02430	COG0456	acetyltransferase
BUW91_RS02440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_RS02460	COG1609	Transcriptional regulator
BUW91_RS02465	COG2814	Major facilitator Superfamily
BUW91_RS02470	COG0673	inositol 2-dehydrogenase activity
BUW91_RS02495	COG1609	Transcriptional regulator
BUW91_RS02510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS02515	COG1522	sequence-specific DNA binding
BUW91_RS02535	COG2814	Major facilitator Superfamily
BUW91_RS02540	COG1309	transcriptional regulator
BUW91_RS02545	COG1187	pseudouridine synthase activity
BUW91_RS02555	COG1942	4-Oxalocrotonate Tautomerase
BUW91_RS02560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUW91_RS02565	COG0747	negative chemotaxis
BUW91_RS02580	COG0084	hydrolase, TatD family'
BUW91_RS02585	COG2962	Rard protein
BUW91_RS02595	COG0628	permease
BUW91_RS02610	COG0604	alcohol dehydrogenase
BUW91_RS02615	COG1620	l-lactate permease
BUW91_RS02625	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_RS02635	COG0564	pseudouridine synthase activity
BUW91_RS02645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_RS02650	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS02655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_RS02655	COG3153	acetyltransferase
BUW91_RS02660	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BUW91_RS02665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BUW91_RS02675	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BUW91_RS02680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_RS02685	COG1268	BioY protein
BUW91_RS02705	COG1959	2 iron, 2 sulfur cluster binding
BUW91_RS02710	COG0604	alcohol dehydrogenase
BUW91_RS02720	COG1126	abc transporter atp-binding protein
BUW91_RS02725	COG0765	amino acid transport
BUW91_RS02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS02735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUW91_RS02740	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BUW91_RS02750	COG0352	thiamine-phosphate diphosphorylase activity
BUW91_RS02755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_RS02770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BUW91_RS02775	COG0351	phosphomethylpyrimidine kinase
BUW91_RS02790	COG0702	epimerase
BUW91_RS02810	COG3842	ATPase activity
BUW91_RS02815	COG2508	Transcriptional regulator
BUW91_RS02830	COG0189	ligase activity
BUW91_RS02835	COG0189	ligase activity
BUW91_RS02845	COG3679	Belongs to the UPF0342 family
BUW91_RS02850	COG0561	phosphatase activity
BUW91_RS02855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BUW91_RS02860	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS02865	COG1024	Enoyl-CoA hydratase
BUW91_RS02880	COG4152	abc transporter atp-binding protein
BUW91_RS02885	COG1668	transmembrane transport
BUW91_RS02895	COG3481	metal-dependent phosphohydrolase, HD sub domain
BUW91_RS02905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_RS02930	COG1846	Transcriptional regulator
BUW91_RS02945	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BUW91_RS02950	COG1695	Transcriptional regulator
BUW91_RS02955	COG2153	protein acetylation
BUW91_RS02960	COG2755	lipolytic protein G-D-S-L family
BUW91_RS02960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BUW91_RS02965	COG0537	adenosine 5'-monophosphoramidase activity
BUW91_RS02970	COG1131	(ABC) transporter
BUW91_RS02975	COG4473	ABC transporter
BUW91_RS02985	COG1473	amidohydrolase
BUW91_RS02990	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS02995	COG3069	C4-dicarboxylate transmembrane transporter activity
BUW91_RS03000	COG2329	Antibiotic biosynthesis monooxygenase
BUW91_RS03005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_RS03010	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BUW91_RS03015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BUW91_RS03020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BUW91_RS03025	COG1309	transcriptional regulator
BUW91_RS03030	COG0768	penicillin binding
BUW91_RS03040	COG2972	Histidine kinase
BUW91_RS03055	COG1234	tRNA 3'-trailer cleavage
BUW91_RS03060	COG0095	Lipoate-protein ligase
BUW91_RS03065	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS03070	COG1024	Enoyl-CoA hydratase
BUW91_RS03185	COG0501	Belongs to the peptidase M48B family
BUW91_RS03190	COG2224	Isocitrate lyase
BUW91_RS03200	COG0823	Involved in the tonB-independent uptake of proteins
BUW91_RS03200	COG4946	Tricorn protease homolog
BUW91_RS03200	COG1506	peptidase
BUW91_RS03205	COG0398	Pfam SNARE associated Golgi protein
BUW91_RS03210	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS03215	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BUW91_RS03220	COG1074	ATP-dependent DNA helicase activity
BUW91_RS03225	COG0420	3'-5' exonuclease activity
BUW91_RS03230	COG0419	ATPase involved in DNA repair
BUW91_RS03235	COG1403	HNH endonuclease
BUW91_RS03270	COG2311	Membrane
BUW91_RS03285	COG0367	asparagine synthase
BUW91_RS03300	COG1562	ergosterol biosynthetic process
BUW91_RS03310	COG1874	Beta-galactosidase
BUW91_RS03310	COG0366	Alpha amylase catalytic
BUW91_RS03315	COG1609	Transcriptional regulator
BUW91_RS03320	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS03325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BUW91_RS03330	COG4187	Peptidase family M20/M25/M40
BUW91_RS03335	COG0833	amino acid
BUW91_RS03345	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS03350	COG1666	GTP binding
BUW91_RS03355	COG2996	Protein conserved in bacteria
BUW91_RS03365	COG1307	EDD domain protein, DegV family
BUW91_RS03370	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS03380	COG0561	phosphatase activity
BUW91_RS03385	COG2151	metal-sulfur cluster biosynthetic enzyme
BUW91_RS03390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUW91_RS03395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BUW91_RS03400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BUW91_RS03405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BUW91_RS03425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BUW91_RS03440	COG0542	response to heat
BUW91_RS03455	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BUW91_RS03460	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BUW91_RS03465	COG2084	Dehydrogenase
BUW91_RS03475	COG2267	carboxylic ester hydrolase activity
BUW91_RS03495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUW91_RS03500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BUW91_RS03505	COG5504	Zn-dependent protease
BUW91_RS03510	COG0444	Belongs to the ABC transporter superfamily
BUW91_RS03515	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS03525	COG0601	transmembrane transport
BUW91_RS03540	COG0180	Tryptophanyl-tRNA synthetase
BUW91_RS03550	COG4166	transmembrane transport
BUW91_RS03555	COG0601	transmembrane transport
BUW91_RS03560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_RS03565	COG0444	Belongs to the ABC transporter superfamily
BUW91_RS03570	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS03575	COG0456	acetyltransferase
BUW91_RS03580	COG1113	amino acid transport
BUW91_RS03585	COG0531	amino acid
BUW91_RS03590	COG1393	Belongs to the ArsC family
BUW91_RS03595	COG0583	DNA-binding transcription factor activity
BUW91_RS03610	COG0861	Integral membrane protein TerC family
BUW91_RS03620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_RS03630	COG1164	Oligoendopeptidase f
BUW91_RS03640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_RS03645	COG2346	COG2346, Truncated hemoglobins
BUW91_RS03650	COG0741	lytic transglycosylase activity
BUW91_RS03665	COG2357	RelA SpoT domain protein
BUW91_RS03675	COG0564	pseudouridine synthase activity
BUW91_RS03685	COG2239	Acts as a magnesium transporter
BUW91_RS03690	COG0569	domain protein
BUW91_RS03690	COG0475	glutathione-regulated potassium exporter activity
BUW91_RS03740	COG0210	DNA helicase
BUW91_RS03750	COG2323	membrane
BUW91_RS03755	COG2153	protein acetylation
BUW91_RS03765	COG2382	esterase
BUW91_RS03775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUW91_RS03785	COG1737	Transcriptional regulator
BUW91_RS03790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_RS03820	COG1522	sequence-specific DNA binding
BUW91_RS03830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_RS03845	COG3142	Participates in the control of copper homeostasis
BUW91_RS03850	COG1113	amino acid transport
BUW91_RS03860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS03865	COG1309	transcriptional regulator
BUW91_RS03870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS03870	COG3711	transcriptional antiterminator
BUW91_RS03875	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUW91_RS03880	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BUW91_RS03885	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUW91_RS03890	COG1486	melibiose metabolic process
BUW91_RS03895	COG3275	phosphorelay sensor kinase activity
BUW91_RS03900	COG3279	Response regulator of the LytR AlgR family
BUW91_RS03910	COG1346	cytolysis
BUW91_RS03920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUW91_RS03925	COG0243	molybdopterin cofactor binding
BUW91_RS03930	COG2223	nitrite transmembrane transporter activity
BUW91_RS03935	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUW91_RS03950	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BUW91_RS03960	COG0028	Belongs to the TPP enzyme family
BUW91_RS03960	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BUW91_RS03965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_RS03965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BUW91_RS03975	COG3527	Alpha-acetolactate decarboxylase
BUW91_RS03980	COG0028	Belongs to the TPP enzyme family
BUW91_RS03990	COG4895	conserved protein (DUF2196)
BUW91_RS04000	COG1733	regulation of RNA biosynthetic process
BUW91_RS04005	COG2814	Major facilitator Superfamily
BUW91_RS04030	COG3052	prosthetic group binding
BUW91_RS04045	COG0784	Response regulator, receiver
BUW91_RS04050	COG4191	Histidine kinase
BUW91_RS04055	COG2066	Belongs to the glutaminase family
BUW91_RS04060	COG1115	amino acid carrier protein
BUW91_RS04065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_RS04075	COG4297	protein containing double-stranded beta helix domain
BUW91_RS04080	COG0531	amino acid
BUW91_RS04090	COG1607	acyl-coa hydrolase
BUW91_RS04095	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BUW91_RS04110	COG0390	transport system, permease component
BUW91_RS04115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BUW91_RS04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BUW91_RS04135	COG1136	(ABC) transporter
BUW91_RS04140	COG0577	efflux transmembrane transporter activity
BUW91_RS04150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BUW91_RS04170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_RS04175	COG0833	amino acid
BUW91_RS04185	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BUW91_RS04190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_RS04200	COG0861	Integral membrane protein TerC family
BUW91_RS04205	COG1301	dicarboxylic acid transport
BUW91_RS04210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BUW91_RS04215	COG3290	protein histidine kinase activity
BUW91_RS04255	COG1476	TRANSCRIPTIONal
BUW91_RS04265	COG1368	sulfuric ester hydrolase activity
BUW91_RS04280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS04285	COG2040	homocysteine
BUW91_RS04295	COG0179	Fumarylacetoacetate (FAA) hydrolase
BUW91_RS04315	COG2851	Citrate transporter
BUW91_RS04320	COG3290	protein histidine kinase activity
BUW91_RS04325	COG4565	transcriptional regulatory protein
BUW91_RS04330	COG3181	Tripartite tricarboxylate transporter family receptor
BUW91_RS04340	COG0583	DNA-binding transcription factor activity
BUW91_RS04345	COG3180	Ammonia monooxygenase
BUW91_RS04350	COG2226	methyltransferase
BUW91_RS04360	COG4175	Glycine betaine
BUW91_RS04360	COG0517	IMP dehydrogenase activity
BUW91_RS04365	COG2113	Glycine betaine
BUW91_RS04370	COG1309	transcriptional regulator
BUW91_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS04390	COG0531	amino acid
BUW91_RS04395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_RS04400	COG1464	Belongs to the NlpA lipoprotein family
BUW91_RS04405	COG2011	ABC-type metal ion transport system permease component
BUW91_RS04410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_RS04425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS04435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BUW91_RS04440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS04445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS04470	COG1737	Transcriptional regulator
BUW91_RS04475	COG1263	PTS System
BUW91_RS04475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS04485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_RS04490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUW91_RS04495	COG1116	anion transmembrane transporter activity
BUW91_RS04500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_RS04505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_RS04520	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUW91_RS04525	COG1733	regulation of RNA biosynthetic process
BUW91_RS04560	COG1511	domain protein
BUW91_RS04570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUW91_RS04575	COG1733	regulation of RNA biosynthetic process
BUW91_RS04580	COG0604	alcohol dehydrogenase
BUW91_RS04580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BUW91_RS04580	COG3321	synthase
BUW91_RS04580	COG4221	oxidoreductase activity
BUW91_RS04585	COG1132	(ABC) transporter
BUW91_RS04590	COG1132	(ABC) transporter
BUW91_RS04600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_RS04605	COG3162	membrane
BUW91_RS04615	COG1414	Transcriptional regulator
BUW91_RS04620	COG0656	L-ascorbic acid biosynthetic process
BUW91_RS04625	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUW91_RS04630	COG1846	Transcriptional regulator
BUW91_RS04635	COG1566	PFAM secretion protein HlyD family protein
BUW91_RS04640	COG2814	Major facilitator Superfamily
BUW91_RS04645	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS04660	COG1609	Transcriptional regulator
BUW91_RS04665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_RS04675	COG1129	ABC transporter
BUW91_RS04680	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS04685	COG1879	ABC-type sugar transport system periplasmic component
BUW91_RS04690	COG3583	domain protein
BUW91_RS04690	COG3584	3D domain protein
BUW91_RS04700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BUW91_RS04705	COG1653	transport
BUW91_RS04750	COG0745	RESPONSE REGULATOR receiver
BUW91_RS04755	COG5002	protein histidine kinase activity
BUW91_RS04765	COG2267	carboxylic ester hydrolase activity
BUW91_RS04780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS04795	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_RS04800	COG2252	PERMEase
BUW91_RS04805	COG1609	Transcriptional regulator
BUW91_RS04810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUW91_RS04815	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS04825	COG0710	3-dehydroquinate dehydratase activity
BUW91_RS04835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS04835	COG1263	PTS System
BUW91_RS04840	COG0366	Alpha amylase catalytic
BUW91_RS04845	COG2188	Transcriptional regulator
BUW91_RS04855	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_RS04860	COG1984	allophanate hydrolase subunit 2
BUW91_RS04865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_RS04870	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_RS04875	COG1272	protein, Hemolysin III
BUW91_RS04890	COG0778	Nitroreductase
BUW91_RS04895	COG0628	permease
BUW91_RS04925	COG2271	Major facilitator Superfamily
BUW91_RS04930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BUW91_RS04935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_RS04940	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS04950	COG0402	S-adenosylhomocysteine deaminase activity
BUW91_RS04955	COG1278	Cold shock
BUW91_RS04960	COG2910	NAD(P)H-binding
BUW91_RS04965	COG0673	inositol 2-dehydrogenase activity
BUW91_RS04970	COG0450	alkyl hydroperoxide reductase
BUW91_RS04975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS05000	COG5001	Diguanylate cyclase
BUW91_RS05000	COG4251	negative regulation of phosphorylation
BUW91_RS05000	COG2203	Gaf domain
BUW91_RS05000	COG3706	GGDEF domain
BUW91_RS05005	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_RS05085	COG1649	PFAM Uncharacterised BCR, COG1649
BUW91_RS05090	COG1737	Transcriptional regulator
BUW91_RS05110	COG1486	melibiose metabolic process
BUW91_RS05120	COG1447	Phosphotransferase system cellobiose-specific component IIA
BUW91_RS05130	COG2971	BadF BadG BcrA BcrD
BUW91_RS05135	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BUW91_RS05140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS05150	COG3037	sugar-specific permease SgaT UlaA
BUW91_RS05155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BUW91_RS05155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_RS05165	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BUW91_RS05180	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS05185	COG4106	trans-aconitate 2-methyltransferase activity
BUW91_RS05190	COG0583	DNA-binding transcription factor activity
BUW91_RS05200	COG0667	Aldo Keto reductase
BUW91_RS05215	COG0154	amidase activity
BUW91_RS05225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BUW91_RS05260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BUW91_RS05270	COG1733	regulation of RNA biosynthetic process
BUW91_RS05285	COG0385	Bile acid
BUW91_RS05295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_RS05300	COG4191	Histidine kinase
BUW91_RS05305	COG0784	Response regulator, receiver
BUW91_RS05320	COG1388	LysM domain
BUW91_RS05320	COG0791	NLP P60 protein
BUW91_RS05330	COG2385	sporulation resulting in formation of a cellular spore
BUW91_RS05335	COG0656	L-ascorbic acid biosynthetic process
BUW91_RS05350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_RS05355	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_RS05375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS05390	COG0477	Major facilitator Superfamily
BUW91_RS05395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_RS05405	COG0640	Transcriptional regulator
BUW91_RS05410	COG5658	integral membrane protein
BUW91_RS05425	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BUW91_RS05445	COG1132	(ABC) transporter
BUW91_RS05455	COG3300	MHYT domain
BUW91_RS05455	COG5001	Diguanylate cyclase
BUW91_RS05485	COG2843	Capsule synthesis protein
BUW91_RS05505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUW91_RS05530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUW91_RS05555	COG1396	sequence-specific DNA binding
BUW91_RS05560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BUW91_RS05570	COG0438	transferase activity, transferring glycosyl groups
BUW91_RS05570	COG0297	glycogen (starch) synthase activity
BUW91_RS05580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BUW91_RS05585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BUW91_RS05590	COG0438	transferase activity, transferring glycosyl groups
BUW91_RS05595	COG2244	polysaccharide biosynthetic process
BUW91_RS05605	COG1482	cell wall glycoprotein biosynthetic process
BUW91_RS05610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BUW91_RS05615	COG3944	biosynthesis protein
BUW91_RS05620	COG0489	protein tyrosine kinase activity
BUW91_RS05625	COG4464	protein tyrosine phosphatase activity
BUW91_RS05630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_RS05635	COG1316	TRANSCRIPTIONal
BUW91_RS05645	COG4464	protein tyrosine phosphatase activity
BUW91_RS05655	COG0028	Belongs to the TPP enzyme family
BUW91_RS05660	COG0069	glutamate synthase activity
BUW91_RS05670	COG2084	Dehydrogenase
BUW91_RS05710	COG4124	Belongs to the glycosyl hydrolase 26 family
BUW91_RS05735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BUW91_RS05740	COG2146	nitrite reductase [NAD(P)H] activity
BUW91_RS05750	COG2116	formate transmembrane transporter activity
BUW91_RS05760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_RS05765	COG4975	Glucose uptake
BUW91_RS05780	COG0534	Mate efflux family protein
BUW91_RS05790	COG1316	TRANSCRIPTIONal
BUW91_RS05800	COG0598	Magnesium transport protein CorA
BUW91_RS05830	COG2188	Transcriptional regulator
BUW91_RS05835	COG0363	glucosamine-6-phosphate deaminase activity
BUW91_RS05840	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUW91_RS05845	COG1263	PTS System
BUW91_RS05845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS05845	COG2190	(PTS) system
BUW91_RS05850	COG1811	Na channel or pump
BUW91_RS05855	COG3961	Belongs to the TPP enzyme family
BUW91_RS05890	COG1131	(ABC) transporter
BUW91_RS05895	COG1253	flavin adenine dinucleotide binding
BUW91_RS05900	COG0789	Transcriptional regulator
BUW91_RS05910	COG0346	lactoylglutathione lyase activity
BUW91_RS05915	COG2105	PFAM AIG2 family protein
BUW91_RS05915	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BUW91_RS05960	COG0456	acetyltransferase
BUW91_RS05965	COG1473	amidohydrolase
BUW91_RS05975	COG4187	Peptidase family M20/M25/M40
BUW91_RS05990	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_RS05990	COG0456	acetyltransferase
BUW91_RS06005	COG2252	PERMEase
BUW91_RS06015	COG3279	Response regulator of the LytR AlgR family
BUW91_RS06020	COG4555	ABC transporter
BUW91_RS06025	COG1668	transmembrane transport
BUW91_RS06035	COG0789	Transcriptional regulator
BUW91_RS06040	COG1846	Transcriptional regulator
BUW91_RS06045	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_RS06045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_RS06065	COG1785	Belongs to the alkaline phosphatase family
BUW91_RS06070	COG3279	Response regulator of the LytR AlgR family
BUW91_RS06075	COG2205	protein histidine kinase activity
BUW91_RS06075	COG0784	Response regulator, receiver
BUW91_RS06080	COG0861	Integral membrane protein TerC family
BUW91_RS06085	COG1191	sigma factor activity
BUW91_RS06115	COG3243	poly(R)-hydroxyalkanoic acid synthase
BUW91_RS06120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUW91_RS06130	COG2186	Transcriptional regulator
BUW91_RS06135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUW91_RS06145	COG0247	lactate metabolic process
BUW91_RS06150	COG1139	Iron-sulfur cluster binding protein
BUW91_RS06155	COG1556	Lactate utilization protein
BUW91_RS06160	COG5002	protein histidine kinase activity
BUW91_RS06165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BUW91_RS06170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BUW91_RS06175	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BUW91_RS06180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BUW91_RS06185	COG0436	Aminotransferase
BUW91_RS06190	COG1850	ribulose-bisphosphate carboxylase activity
BUW91_RS06195	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BUW91_RS06200	COG0235	Class ii aldolase
BUW91_RS06205	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BUW91_RS06215	COG1129	ABC transporter
BUW91_RS06220	COG1172	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS06245	COG1846	Transcriptional regulator
BUW91_RS06255	COG4191	Histidine kinase
BUW91_RS06265	COG0542	response to heat
BUW91_RS06270	COG1757	Na H antiporter
BUW91_RS06280	COG0300	oxidoreductase activity
BUW91_RS06285	COG0697	spore germination
BUW91_RS06305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BUW91_RS06310	COG0720	synthase
BUW91_RS06320	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BUW91_RS06325	COG0702	epimerase
BUW91_RS06335	COG4873	Protein conserved in bacteria
BUW91_RS06355	COG3773	Cell wall hydrolase
BUW91_RS06400	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BUW91_RS06400	COG0646	methionine synthase
BUW91_RS06405	COG3949	Membrane
BUW91_RS06415	COG0307	riboflavin synthase, alpha
BUW91_RS06425	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BUW91_RS06435	COG3711	transcriptional antiterminator
BUW91_RS06440	COG2190	(PTS) system
BUW91_RS06440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS06440	COG1263	PTS System
BUW91_RS06455	COG1346	cytolysis
BUW91_RS06465	COG0583	DNA-binding transcription factor activity
BUW91_RS06480	COG0456	acetyltransferase
BUW91_RS06485	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS06490	COG0778	Nitroreductase
BUW91_RS06495	COG0436	Aminotransferase
BUW91_RS06515	COG0835	chemotaxis
BUW91_RS06515	COG0784	Response regulator, receiver
BUW91_RS06525	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS06530	COG0248	Ppx GppA phosphatase
BUW91_RS06545	COG1408	metallophosphoesterase
BUW91_RS06550	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS06555	COG2200	EAL domain
BUW91_RS06570	COG4703	Protein of unknown function (DUF1797)
BUW91_RS06575	COG0517	IMP dehydrogenase activity
BUW91_RS06580	COG0583	DNA-binding transcription factor activity
BUW91_RS06585	COG2171	N-acyltransferase activity
BUW91_RS06590	COG1473	amidohydrolase
BUW91_RS06600	COG0668	transmembrane transport
BUW91_RS06605	COG0450	alkyl hydroperoxide reductase
BUW91_RS06610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS06615	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_RS06625	COG1132	(ABC) transporter
BUW91_RS06630	COG1132	(ABC) transporter
BUW91_RS06635	COG0569	domain protein
BUW91_RS06640	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUW91_RS06645	COG5503	Protein of unknown function (DUF1447)
BUW91_RS06650	COG0561	phosphatase activity
BUW91_RS06675	COG0022	dehydrogenase e1 component
BUW91_RS06680	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_RS06705	COG1982	Orn Lys Arg decarboxylase major
BUW91_RS06710	COG4476	Belongs to the UPF0223 family
BUW91_RS06715	COG4493	Belongs to the UPF0637 family
BUW91_RS06725	COG0483	inositol monophosphate 1-phosphatase activity
BUW91_RS06735	COG1217	gtp-binding protein TYPA
BUW91_RS06750	COG4896	Protein conserved in bacteria
BUW91_RS06765	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BUW91_RS06770	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUW91_RS06775	COG4838	Belongs to the UPF0358 family
BUW91_RS06780	COG0772	Belongs to the SEDS family
BUW91_RS06785	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUW91_RS06790	COG1612	heme a metabolic process
BUW91_RS06795	COG0109	protoheme IX farnesyltransferase activity
BUW91_RS06820	COG3336	cytochrome c oxidase
BUW91_RS06830	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BUW91_RS06835	COG2340	Cysteine-rich secretory protein family
BUW91_RS06845	COG2738	Putative neutral zinc metallopeptidase
BUW91_RS06850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS06855	COG1694	Mazg nucleotide pyrophosphohydrolase
BUW91_RS06860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BUW91_RS06865	COG1803	Methylglyoxal synthase
BUW91_RS06870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_RS06875	COG0438	transferase activity, transferring glycosyl groups
BUW91_RS06880	COG0617	tRNA 3'-terminal CCA addition
BUW91_RS06885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BUW91_RS06885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BUW91_RS06895	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BUW91_RS06900	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BUW91_RS06905	COG1199	ATP-dependent helicase activity
BUW91_RS06905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BUW91_RS06925	COG0436	Aminotransferase
BUW91_RS06930	COG0017	Asparaginyl-tRNA synthetase
BUW91_RS06935	COG3935	DnaD domain protein
BUW91_RS06940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BUW91_RS06950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_RS06950	COG4499	WXG100 protein secretion system (Wss), protein YukC
BUW91_RS06955	COG3331	DNA recombination
BUW91_RS06995	COG5337	Spore coat protein CotH
BUW91_RS07010	COG0626	cystathionine gamma-synthase activity
BUW91_RS07015	COG0626	cystathionine gamma-synthase activity
BUW91_RS07050	COG3706	GGDEF domain
BUW91_RS07060	COG1111	helicase
BUW91_RS07060	COG1205	dead DEAH box helicase
BUW91_RS07065	COG3359	exonuclease
BUW91_RS07075	COG4474	Belongs to the UPF0398 family
BUW91_RS07080	COG3599	regulation of cell shape
BUW91_RS07110	COG2197	response regulator
BUW91_RS07115	COG0366	Alpha amylase catalytic
BUW91_RS07120	COG0116	Belongs to the methyltransferase superfamily
BUW91_RS07135	COG1175	transmembrane transport
BUW91_RS07145	COG3842	ATPase activity
BUW91_RS07155	COG1199	ATP-dependent helicase activity
BUW91_RS07160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUW91_RS07165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_RS07170	COG2233	PERMEase
BUW91_RS07175	COG0583	DNA-binding transcription factor activity
BUW91_RS07180	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS07190	COG3424	synthase
BUW91_RS07195	COG1755	Isoprenylcysteine carboxyl methyltransferase
BUW91_RS07200	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUW91_RS07205	COG3541	Predicted nucleotidyltransferase
BUW91_RS07230	COG0328	RNA-DNA hybrid ribonuclease activity
BUW91_RS07235	COG0328	RNA-DNA hybrid ribonuclease activity
BUW91_RS07260	COG2814	Major facilitator Superfamily
BUW91_RS07270	COG2233	PERMEase
BUW91_RS07275	COG2362	D-Aminopeptidase
BUW91_RS07280	COG0601	transmembrane transport
BUW91_RS07285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_RS07290	COG0444	Belongs to the ABC transporter superfamily
BUW91_RS07295	COG4166	transmembrane transport
BUW91_RS07300	COG1619	proteins homologs of microcin C7 resistance protein MccF
BUW91_RS07305	COG0791	NLP P60 protein
BUW91_RS07310	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS07330	COG5001	Diguanylate cyclase
BUW91_RS07330	COG3300	MHYT domain
BUW91_RS07360	COG2197	response regulator
BUW91_RS07365	COG4585	Histidine kinase
BUW91_RS07370	COG3239	Fatty acid desaturase
BUW91_RS07375	COG2205	protein histidine kinase activity
BUW91_RS07385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_RS07400	COG1388	LysM domain
BUW91_RS07400	COG0791	NLP P60 protein
BUW91_RS07405	COG1819	glycosyl
BUW91_RS07410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_RS07425	COG2814	Major facilitator Superfamily
BUW91_RS07440	COG3964	amidohydrolase
BUW91_RS07460	COG2188	Transcriptional regulator
BUW91_RS07470	COG0434	BtpA family
BUW91_RS07475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_RS07485	COG1785	Belongs to the alkaline phosphatase family
BUW91_RS07490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_RS07495	COG1404	Belongs to the peptidase S8 family
BUW91_RS07505	COG1846	Transcriptional regulator
BUW91_RS07510	COG1566	PFAM secretion protein HlyD family protein
BUW91_RS07515	COG2814	Major facilitator Superfamily
BUW91_RS07520	COG1846	Transcriptional regulator
BUW91_RS07545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS07550	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_RS07555	COG1120	ATPase activity
BUW91_RS07560	COG0492	ferredoxin-NADP+ reductase activity
BUW91_RS07570	COG2814	Major facilitator Superfamily
BUW91_RS07590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_RS07595	COG1733	regulation of RNA biosynthetic process
BUW91_RS07600	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BUW91_RS07610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_RS07620	COG3448	diguanylate cyclase activity
BUW91_RS07620	COG4175	Glycine betaine
BUW91_RS07625	COG4176	ABC-type proline glycine betaine transport system permease component
BUW91_RS07640	COG2205	protein histidine kinase activity
BUW91_RS07640	COG0784	Response regulator, receiver
BUW91_RS07645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUW91_RS07650	COG2208	phosphoserine phosphatase activity
BUW91_RS07660	COG0531	amino acid
BUW91_RS07670	COG1011	Hydrolase
BUW91_RS07675	COG0405	Gamma-glutamyltransferase
BUW91_RS07680	COG1621	beta-fructofuranosidase activity
BUW91_RS07685	COG1621	beta-fructofuranosidase activity
BUW91_RS07690	COG2193	ferroxidase activity
BUW91_RS07695	COG0477	Major facilitator Superfamily
BUW91_RS07700	COG0156	8-amino-7-oxononanoate synthase activity
BUW91_RS07705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BUW91_RS07715	COG2814	Major facilitator Superfamily
BUW91_RS07730	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS07735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS07745	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS07750	COG1113	amino acid transport
BUW91_RS07760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BUW91_RS07780	COG1113	amino acid transport
BUW91_RS07800	COG1609	Transcriptional regulator
BUW91_RS07815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BUW91_RS07820	COG1621	beta-fructofuranosidase activity
BUW91_RS07825	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BUW91_RS07825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BUW91_RS07830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS07835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS07840	COG3715	PTS system
BUW91_RS07845	COG3716	PTS system mannose fructose sorbose family IID component
BUW91_RS07850	COG1621	beta-fructofuranosidase activity
BUW91_RS07855	COG0765	amino acid transport
BUW91_RS07860	COG0765	amino acid transport
BUW91_RS07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS07870	COG1464	Belongs to the NlpA lipoprotein family
BUW91_RS07875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_RS07880	COG2011	ABC-type metal ion transport system permease component
BUW91_RS07900	COG1464	Belongs to the NlpA lipoprotein family
BUW91_RS07905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_RS07910	COG2011	ABC-type metal ion transport system permease component
BUW91_RS07915	COG1464	Belongs to the NlpA lipoprotein family
BUW91_RS07920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS07925	COG0024	Methionine aminopeptidase
BUW91_RS07935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUW91_RS07945	COG0656	L-ascorbic acid biosynthetic process
BUW91_RS07950	COG2986	histidine ammonia-lyase
BUW91_RS07960	COG1228	amidohydrolase
BUW91_RS07965	COG0010	Belongs to the arginase family
BUW91_RS07970	COG1846	Transcriptional regulator
BUW91_RS07980	COG0473	3-isopropylmalate dehydrogenase activity
BUW91_RS07985	COG1288	antiporter activity
BUW91_RS07990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BUW91_RS08020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS08040	COG2364	Membrane
BUW91_RS08045	COG1846	Transcriptional regulator
BUW91_RS08050	COG0456	acetyltransferase
BUW91_RS08085	COG3848	Pyruvate phosphate dikinase
BUW91_RS08085	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_RS08090	COG1309	transcriptional regulator
BUW91_RS08095	COG2814	Major facilitator Superfamily
BUW91_RS08100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BUW91_RS08105	COG3958	Transketolase
BUW91_RS08110	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS08115	COG2186	Transcriptional regulator
BUW91_RS08125	COG0205	6-phosphofructokinase activity
BUW91_RS08130	COG0698	ribose 5-phosphate isomerase
BUW91_RS08155	COG0791	NLP P60 protein
BUW91_RS08155	COG1388	LysM domain
BUW91_RS08160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BUW91_RS08175	COG2318	DinB family
BUW91_RS08200	COG0583	DNA-binding transcription factor activity
BUW91_RS08205	COG0596	Alpha beta hydrolase
BUW91_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS08250	COG5002	protein histidine kinase activity
BUW91_RS08250	COG3850	Histidine kinase
BUW91_RS08255	COG0745	RESPONSE REGULATOR receiver
BUW91_RS08260	COG0586	Pfam SNARE associated Golgi protein
BUW91_RS08280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_RS08290	COG0697	spore germination
BUW91_RS08320	COG0387	Pfam Sodium calcium exchanger
BUW91_RS08325	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS08340	COG1309	transcriptional regulator
BUW91_RS08345	COG0861	Integral membrane protein TerC family
BUW91_RS08355	COG5577	PFAM Coat F domain
BUW91_RS08385	COG3813	Protein conserved in bacteria
BUW91_RS08415	COG2076	Multidrug Resistance protein
BUW91_RS08435	COG1278	Cold shock
BUW91_RS08450	COG1278	Cold shock
BUW91_RS08465	COG0028	Belongs to the TPP enzyme family
BUW91_RS08500	COG2172	sigma factor antagonist activity
BUW91_RS08505	COG3858	chitin binding
BUW91_RS08505	COG1388	LysM domain
BUW91_RS08510	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS08515	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_RS08535	COG2226	methyltransferase
BUW91_RS08545	COG1733	regulation of RNA biosynthetic process
BUW91_RS08550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS08565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS08570	COG3420	alginic acid biosynthetic process
BUW91_RS08585	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_RS08590	COG0640	Transcriptional regulator
BUW91_RS08595	COG0640	Transcriptional regulator
BUW91_RS08600	COG0346	lactoylglutathione lyase activity
BUW91_RS08605	COG0589	response to stress
BUW91_RS08605	COG0475	glutathione-regulated potassium exporter activity
BUW91_RS08615	COG2076	Multidrug Resistance protein
BUW91_RS08620	COG2076	Multidrug Resistance protein
BUW91_RS08650	COG0488	(ABC) transporter
BUW91_RS08665	COG3227	Zinc metalloprotease (Elastase)
BUW91_RS08680	COG0583	DNA-binding transcription factor activity
BUW91_RS08685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BUW91_RS08695	COG0753	catalase activity
BUW91_RS08710	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS08715	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS08735	COG0384	phenazine biosynthesis protein PhzF
BUW91_RS08745	COG5577	PFAM Coat F domain
BUW91_RS08755	COG1063	alcohol dehydrogenase
BUW91_RS08760	COG5577	PFAM Coat F domain
BUW91_RS08775	COG2814	Major facilitator Superfamily
BUW91_RS08785	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS08800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS08815	COG0789	Transcriptional regulator
BUW91_RS08820	COG1278	Cold shock
BUW91_RS08870	COG1113	amino acid transport
BUW91_RS08880	COG2207	Transcriptional regulator
BUW91_RS08890	COG2376	Dihydroxyacetone kinase
BUW91_RS08910	COG0745	RESPONSE REGULATOR receiver
BUW91_RS08915	COG0745	RESPONSE REGULATOR receiver
BUW91_RS08920	COG5002	protein histidine kinase activity
BUW91_RS08925	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS08935	COG2851	Citrate transporter
BUW91_RS08985	COG2318	DinB family
BUW91_RS08990	COG2890	protein-(glutamine-N5) methyltransferase activity
BUW91_RS09030	COG2311	Membrane
BUW91_RS09065	COG1114	Component of the transport system for branched-chain amino acids
BUW91_RS09075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BUW91_RS09085	COG4282	regulation of fungal-type cell wall biogenesis
BUW91_RS09115	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_RS09115	COG3848	Pyruvate phosphate dikinase
BUW91_RS09120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BUW91_RS09130	COG0601	transmembrane transport
BUW91_RS09135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_RS09140	COG0444	Belongs to the ABC transporter superfamily
BUW91_RS09145	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS09150	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BUW91_RS09155	COG0477	Major facilitator Superfamily
BUW91_RS09175	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS09210	COG0517	IMP dehydrogenase activity
BUW91_RS09245	COG1070	Carbohydrate kinase
BUW91_RS09250	COG0477	Major facilitator Superfamily
BUW91_RS09250	COG2814	Major facilitator Superfamily
BUW91_RS09260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BUW91_RS09265	COG1845	cytochrome c oxidase, subunit III
BUW91_RS09275	COG0589	response to stress
BUW91_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS09285	COG1612	heme a metabolic process
BUW91_RS09290	COG2072	flavoprotein involved in K transport
BUW91_RS09300	COG2252	PERMEase
BUW91_RS09310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUW91_RS09315	COG0022	dehydrogenase e1 component
BUW91_RS09320	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_RS09325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BUW91_RS09330	COG3284	Transcriptional regulator
BUW91_RS09335	COG1063	alcohol dehydrogenase
BUW91_RS09365	COG0628	permease
BUW91_RS09370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_RS09380	COG2211	Major facilitator Superfamily
BUW91_RS09405	COG0589	response to stress
BUW91_RS09410	COG5002	protein histidine kinase activity
BUW91_RS09420	COG1937	Protein conserved in bacteria
BUW91_RS09425	COG2608	mercury ion transmembrane transporter activity
BUW91_RS09430	COG2217	Heavy metal translocating P-type atpase
BUW91_RS09440	COG1388	LysM domain
BUW91_RS09445	COG2271	Major facilitator Superfamily
BUW91_RS09475	COG0640	Transcriptional regulator
BUW91_RS09480	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BUW91_RS09485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_RS09485	COG0551	DNA topoisomerase type I activity
BUW91_RS09490	COG5444	nuclease activity
BUW91_RS09500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_RS09510	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BUW91_RS09515	COG2323	membrane
BUW91_RS09530	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_RS09535	COG1802	Transcriptional regulator
BUW91_RS09540	COG0473	3-isopropylmalate dehydrogenase activity
BUW91_RS09545	COG2814	Major facilitator Superfamily
BUW91_RS09550	COG1733	regulation of RNA biosynthetic process
BUW91_RS09555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUW91_RS09555	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BUW91_RS09560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUW91_RS09560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BUW91_RS09585	COG5566	PFAM Mor transcription activator
BUW91_RS09600	COG0561	phosphatase activity
BUW91_RS09605	COG1876	peptidase activity
BUW91_RS09650	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BUW91_RS09665	COG0386	Belongs to the glutathione peroxidase family
BUW91_RS09670	COG1418	mRNA catabolic process
BUW91_RS09680	COG1413	lyase activity
BUW91_RS09685	COG0726	polysaccharide deacetylase
BUW91_RS09695	COG2521	methyltransferase
BUW91_RS09695	COG2136	Putative SAM-dependent methyltransferase
BUW91_RS09705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS09710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_RS09720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BUW91_RS09725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BUW91_RS09735	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BUW91_RS09740	COG0406	alpha-ribazole phosphatase activity
BUW91_RS09750	COG2096	Adenosyltransferase
BUW91_RS09755	COG2962	Rard protein
BUW91_RS09765	COG0523	cobalamin synthesis protein
BUW91_RS09770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUW91_RS09775	COG0322	excinuclease ABC activity
BUW91_RS09785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_RS09790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_RS09795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BUW91_RS09805	COG3011	Protein conserved in bacteria
BUW91_RS09810	COG1595	DNA-templated transcription, initiation
BUW91_RS09830	COG2002	toxin-antitoxin pair type II binding
BUW91_RS09835	COG0534	Mate efflux family protein
BUW91_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS09865	COG1368	sulfuric ester hydrolase activity
BUW91_RS09875	COG3853	Toxic anion resistance protein (TelA)
BUW91_RS09905	COG5002	protein histidine kinase activity
BUW91_RS09915	COG1823	symporter activity
BUW91_RS09920	COG1523	belongs to the glycosyl hydrolase 13 family
BUW91_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS09930	COG2124	cytochrome p450
BUW91_RS09935	COG2112	serine threonine protein kinase
BUW91_RS09945	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BUW91_RS09965	COG3361	conserved protein (COG2071)
BUW91_RS09970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BUW91_RS09975	COG1757	Na H antiporter
BUW91_RS09985	COG0833	amino acid
BUW91_RS09990	COG3594	Acyltransferase
BUW91_RS09995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BUW91_RS10000	COG0745	RESPONSE REGULATOR receiver
BUW91_RS10005	COG5002	protein histidine kinase activity
BUW91_RS10010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BUW91_RS10015	COG3104	oligopeptide transport
BUW91_RS10025	COG0281	malic enzyme
BUW91_RS10030	COG3493	citrate carrier protein
BUW91_RS10035	COG0561	phosphatase activity
BUW91_RS10040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS10050	COG0456	acetyltransferase
BUW91_RS10055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BUW91_RS10060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS10065	COG0765	amino acid transport
BUW91_RS10070	COG0765	amino acid transport
BUW91_RS10075	COG1126	abc transporter atp-binding protein
BUW91_RS10080	COG0196	riboflavin kinase activity
BUW91_RS10085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS10095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_RS10115	COG2188	Transcriptional regulator
BUW91_RS10120	COG1070	Carbohydrate kinase
BUW91_RS10125	COG2140	Oxalate decarboxylase
BUW91_RS10130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_RS10150	COG0363	glucosamine-6-phosphate deaminase activity
BUW91_RS10180	COG1611	Belongs to the LOG family
BUW91_RS10185	COG0281	malic enzyme
BUW91_RS10190	COG3402	PFAM membrane-flanked domain
BUW91_RS10195	COG3428	Bacterial PH domain
BUW91_RS10210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_RS10215	COG0109	protoheme IX farnesyltransferase activity
BUW91_RS10220	COG4195	phage-related replication protein
BUW91_RS10230	COG0789	Transcriptional regulator
BUW91_RS10260	COG0583	DNA-binding transcription factor activity
BUW91_RS10265	COG0069	glutamate synthase activity
BUW91_RS10265	COG0067	glutamate synthase
BUW91_RS10265	COG0070	glutamate synthase
BUW91_RS10270	COG0493	'glutamate synthase
BUW91_RS10290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BUW91_RS10305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_RS10320	COG1846	Transcriptional regulator
BUW91_RS10325	COG1380	Effector of murein hydrolase LrgA
BUW91_RS10330	COG1346	cytolysis
BUW91_RS10335	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS10355	COG0463	Glycosyl transferase, family 2
BUW91_RS10365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_RS10370	COG0745	RESPONSE REGULATOR receiver
BUW91_RS10380	COG5583	Uncharacterized small protein (DUF2292)
BUW91_RS10390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BUW91_RS10400	COG4208	sulfate ABC transporter
BUW91_RS10415	COG0745	RESPONSE REGULATOR receiver
BUW91_RS10440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS10450	COG1349	DNA-binding transcription factor activity
BUW91_RS10455	COG1105	Belongs to the carbohydrate kinase PfkB family
BUW91_RS10460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS10460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUW91_RS10460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BUW91_RS10465	COG0527	aspartate kinase activity
BUW91_RS10475	COG2032	superoxide dismutase activity
BUW91_RS10480	COG1233	COG1233 Phytoene dehydrogenase and related
BUW91_RS10490	COG0300	oxidoreductase activity
BUW91_RS10495	COG0640	Transcriptional regulator
BUW91_RS10500	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS10505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BUW91_RS10520	COG0733	neurotransmitter:sodium symporter activity
BUW91_RS10530	COG3773	Cell wall hydrolase
BUW91_RS10550	COG0673	inositol 2-dehydrogenase activity
BUW91_RS10555	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_RS10560	COG2094	Belongs to the DNA glycosylase MPG family
BUW91_RS10570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUW91_RS10580	COG0454	-acetyltransferase
BUW91_RS10595	COG2814	Major facilitator Superfamily
BUW91_RS10610	COG3871	stress protein (general stress protein 26)
BUW91_RS10635	COG1595	DNA-templated transcription, initiation
BUW91_RS10645	COG0714	Associated with various cellular activities
BUW91_RS10650	COG4548	von Willebrand factor, type A
BUW91_RS10655	COG0697	spore germination
BUW91_RS10665	COG2207	Transcriptional regulator
BUW91_RS10670	COG1994	Peptidase M50
BUW91_RS10675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS10680	COG1119	ATPase activity
BUW91_RS10695	COG1657	PFAM Prenyltransferase squalene oxidase
BUW91_RS10705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BUW91_RS10705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BUW91_RS10715	COG0384	phenazine biosynthesis protein PhzF
BUW91_RS10730	COG1378	Sugar-specific transcriptional regulator TrmB
BUW91_RS10735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_RS10740	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS10760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS10765	COG1279	arginine transmembrane transporter activity
BUW91_RS10795	COG1396	sequence-specific DNA binding
BUW91_RS10810	COG0494	nUDIX hydrolase
BUW91_RS10815	COG1335	isochorismatase
BUW91_RS10820	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BUW91_RS10825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUW91_RS10830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BUW91_RS10835	COG1098	S1 RNA binding domain
BUW91_RS10840	COG1404	Belongs to the peptidase S8 family
BUW91_RS10845	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS10850	COG1254	Belongs to the acylphosphatase family
BUW91_RS10855	COG2223	nitrite transmembrane transporter activity
BUW91_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS10865	COG4974	Belongs to the 'phage' integrase family
BUW91_RS10880	COG1396	sequence-specific DNA binding
BUW91_RS11030	COG4824	toxin secretion phage lysis holin
BUW91_RS11085	COG0662	Cupin 2, conserved barrel domain protein
BUW91_RS11085	COG2207	Transcriptional regulator
BUW91_RS11090	COG0697	spore germination
BUW91_RS11095	COG0488	(ABC) transporter
BUW91_RS11100	COG0697	spore germination
BUW91_RS11125	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_RS11130	COG1757	Na H antiporter
BUW91_RS11135	COG1609	Transcriptional regulator
BUW91_RS11145	COG1533	DNA photolyase activity
BUW91_RS11165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_RS11165	COG0551	DNA topoisomerase type I activity
BUW91_RS11175	COG0446	pyridine nucleotide-disulphide oxidoreductase
BUW91_RS11225	COG1757	Na H antiporter
BUW91_RS11250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS11300	COG0514	ATP-dependent DNA helicase (RecQ)
BUW91_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS11335	COG1575	Belongs to the MenA family. Type 1 subfamily
BUW91_RS11340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BUW91_RS11355	COG2814	Major facilitator Superfamily
BUW91_RS11360	COG0583	DNA-binding transcription factor activity
BUW91_RS11365	COG1725	Transcriptional regulator
BUW91_RS11370	COG1131	(ABC) transporter
BUW91_RS11380	COG1595	DNA-templated transcription, initiation
BUW91_RS11395	COG1764	response to oxidative stress
BUW91_RS11400	COG1846	Transcriptional regulator
BUW91_RS11415	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BUW91_RS11425	COG3584	3D domain protein
BUW91_RS11425	COG1388	LysM domain
BUW91_RS11445	COG5002	protein histidine kinase activity
BUW91_RS11450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_RS11455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BUW91_RS11460	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BUW91_RS11475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BUW91_RS11490	COG2409	Drug exporters of the RND superfamily
BUW91_RS11495	COG1834	amidinotransferase
BUW91_RS11590	COG0110	maltose O-acetyltransferase activity
BUW91_RS11595	COG0346	lactoylglutathione lyase activity
BUW91_RS11605	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS11615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BUW91_RS11625	COG2176	DNA-directed DNA polymerase activity
BUW91_RS11640	COG0114	fumarate hydratase activity
BUW91_RS11650	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_RS11650	COG3757	hydrolase, family 25
BUW91_RS11660	COG5002	protein histidine kinase activity
BUW91_RS11700	COG0778	Nitroreductase
BUW91_RS11710	COG0300	oxidoreductase activity
BUW91_RS11715	COG3290	protein histidine kinase activity
BUW91_RS11720	COG4565	transcriptional regulatory protein
BUW91_RS11725	COG2851	Citrate transporter
BUW91_RS11735	COG2610	gluconate transmembrane transporter activity
BUW91_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS11745	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUW91_RS11770	COG4122	O-methyltransferase activity
BUW91_RS11775	COG0583	DNA-binding transcription factor activity
BUW91_RS11785	COG1301	dicarboxylic acid transport
BUW91_RS11790	COG0019	diaminopimelate decarboxylase activity
BUW91_RS11800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_RS11810	COG4191	Histidine kinase
BUW91_RS11820	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS11825	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS11830	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS11840	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_RS11845	COG1024	Enoyl-CoA hydratase
BUW91_RS11860	COG2045	Belongs to the ComB family
BUW91_RS11865	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS11875	COG1024	Enoyl-CoA hydratase
BUW91_RS11890	COG1141	Ferredoxin
BUW91_RS11900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_RS11910	COG0183	Belongs to the thiolase family
BUW91_RS11915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_RS11920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS11940	COG1509	lysine 2,3-aminomutase activity
BUW91_RS11950	COG0833	amino acid
BUW91_RS11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS11970	COG1979	alcohol dehydrogenase
BUW91_RS11975	COG0738	Major facilitator superfamily
BUW91_RS11980	COG1181	Belongs to the D-alanine--D-alanine ligase family
BUW91_RS12000	COG3977	Valine--pyruvate aminotransferase
BUW91_RS12005	COG3773	Cell wall hydrolase
BUW91_RS12030	COG0531	amino acid
BUW91_RS12035	COG2814	Major facilitator Superfamily
BUW91_RS12040	COG1846	Transcriptional regulator
BUW91_RS12045	COG2409	Drug exporters of the RND superfamily
BUW91_RS12045	COG1033	growth of symbiont in host cell
BUW91_RS12050	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS12050	COG2202	Pas domain
BUW91_RS12055	COG3832	glyoxalase III activity
BUW91_RS12060	COG0640	Transcriptional regulator
BUW91_RS12070	COG2267	carboxylic ester hydrolase activity
BUW91_RS12080	COG3386	PFAM SMP-30 Gluconolaconase
BUW91_RS12090	COG2368	4-hydroxyphenylacetate
BUW91_RS12095	COG3739	integral membrane protein
BUW91_RS12105	COG0326	Molecular chaperone. Has ATPase activity
BUW91_RS12110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_RS12130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUW91_RS12135	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_RS12135	COG3757	hydrolase, family 25
BUW91_RS12145	COG0697	spore germination
BUW91_RS12150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS12165	COG4572	Cation transport regulator
BUW91_RS12170	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BUW91_RS12175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUW91_RS12190	COG3011	Protein conserved in bacteria
BUW91_RS12280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_RS12295	COG0494	nUDIX hydrolase
BUW91_RS12300	COG0702	epimerase
BUW91_RS12310	COG1846	Transcriptional regulator
BUW91_RS12315	COG2720	vancomycin resistance protein
BUW91_RS12320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUW91_RS12345	COG0076	glutamate decarboxylase activity
BUW91_RS12375	COG2116	formate transmembrane transporter activity
BUW91_RS12380	COG5609	conserved protein (DUF2294)
BUW91_RS12395	COG2271	Major facilitator Superfamily
BUW91_RS12400	COG0277	FAD linked oxidase domain protein
BUW91_RS12405	COG0840	transmembrane signaling receptor activity
BUW91_RS12415	COG0622	Phosphoesterase
BUW91_RS12425	COG1408	metallophosphoesterase
BUW91_RS12430	COG3663	DNA glycosylase
BUW91_RS12435	COG3883	PFAM NLP P60 protein
BUW91_RS12435	COG0791	NLP P60 protein
BUW91_RS12440	COG1587	Uroporphyrinogen-III synthase
BUW91_RS12445	COG1414	Transcriptional regulator
BUW91_RS12450	COG0439	Biotin carboxylase
BUW91_RS12455	COG0511	ligase activity, forming carbon-carbon bonds
BUW91_RS12460	COG1984	allophanate hydrolase subunit 2
BUW91_RS12465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_RS12470	COG4336	lyase activity
BUW91_RS12475	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_RS12480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BUW91_RS12495	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS12500	COG1268	BioY protein
BUW91_RS12505	COG0183	Belongs to the thiolase family
BUW91_RS12525	COG0431	NADPH-dependent FMN reductase
BUW91_RS12530	COG2197	response regulator
BUW91_RS12535	COG2203	Gaf domain
BUW91_RS12535	COG4585	Histidine kinase
BUW91_RS12555	COG0697	spore germination
BUW91_RS12565	COG2153	protein acetylation
BUW91_RS12570	COG0129	dihydroxy-acid dehydratase activity
BUW91_RS12575	COG2267	carboxylic ester hydrolase activity
BUW91_RS12580	COG1227	inorganic diphosphatase activity
BUW91_RS12600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS12610	COG0204	Acyl-transferase
BUW91_RS12615	COG2233	PERMEase
BUW91_RS12620	COG3195	allantoin biosynthetic process
BUW91_RS12620	COG3648	Uricase
BUW91_RS12630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS12645	COG1914	H( )-stimulated, divalent metal cation uptake system
BUW91_RS12660	COG1011	Hydrolase
BUW91_RS12665	COG1846	Transcriptional regulator
BUW91_RS12675	COG4974	Belongs to the 'phage' integrase family
BUW91_RS12690	COG0531	amino acid
BUW91_RS12695	COG4302	ethanolamine ammonia-lyase activity
BUW91_RS12700	COG4303	Ethanolamine ammonia lyase large subunit
BUW91_RS12705	COG4819	ethanolamine utilization protein
BUW91_RS12715	COG0833	amino acid
BUW91_RS12725	COG1247	-acetyltransferase
BUW91_RS12730	COG1335	isochorismatase
BUW91_RS12740	COG3403	YqcI/YcgG family
BUW91_RS12745	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS12750	COG2267	carboxylic ester hydrolase activity
BUW91_RS12755	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS12760	COG0187	DNA topoisomerase II activity
BUW91_RS12765	COG1832	CoA-binding protein
BUW91_RS12770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BUW91_RS12775	COG4841	protein insertion into membrane
BUW91_RS12780	COG0824	Thioesterase
BUW91_RS12810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS12815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BUW91_RS12835	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BUW91_RS12870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BUW91_RS12875	COG2068	MobA-Related Protein
BUW91_RS12880	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BUW91_RS12935	COG1183	phosphatidylcholine synthase activity
BUW91_RS12950	COG2814	Major facilitator Superfamily
BUW91_RS12955	COG1683	Conserved Protein
BUW91_RS12960	COG1302	Protein conserved in bacteria
BUW91_RS12975	COG1295	ribonuclease BN
BUW91_RS12985	COG1115	amino acid carrier protein
BUW91_RS12990	COG2814	Major facilitator Superfamily
BUW91_RS13000	COG2814	Major facilitator Superfamily
BUW91_RS13005	COG0789	Transcriptional regulator
BUW91_RS13015	COG0288	reversible hydration of carbon dioxide
BUW91_RS13020	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_RS13025	COG0745	RESPONSE REGULATOR receiver
BUW91_RS13030	COG5002	protein histidine kinase activity
BUW91_RS13040	COG0477	Major facilitator Superfamily
BUW91_RS13045	COG4282	regulation of fungal-type cell wall biogenesis
BUW91_RS13050	COG0531	amino acid
BUW91_RS13060	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_RS13065	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BUW91_RS13135	COG1363	Peptidase, m42
BUW91_RS13145	COG1114	Component of the transport system for branched-chain amino acids
BUW91_RS13165	COG0004	ammonium transporteR
BUW91_RS13180	COG1252	NADH dehydrogenase
BUW91_RS13185	COG0679	Auxin Efflux Carrier
BUW91_RS13190	COG0281	malic enzyme
BUW91_RS13195	COG1473	amidohydrolase
BUW91_RS13200	COG2271	Major facilitator Superfamily
BUW91_RS13220	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BUW91_RS13225	COG0163	prenyltransferase activity
BUW91_RS13230	COG0583	DNA-binding transcription factor activity
BUW91_RS13235	COG0679	Auxin Efflux Carrier
BUW91_RS13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS13260	COG0247	lactate metabolic process
BUW91_RS13265	COG0277	FAD linked oxidase domain protein
BUW91_RS13270	COG3835	regulator
BUW91_RS13275	COG0693	protein deglycase activity
BUW91_RS13285	COG2610	gluconate transmembrane transporter activity
BUW91_RS13305	COG1131	(ABC) transporter
BUW91_RS13315	COG2197	response regulator
BUW91_RS13350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS13360	COG0586	Pfam SNARE associated Golgi protein
BUW91_RS13365	COG1515	deoxyribonuclease V activity
BUW91_RS13370	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_RS13410	COG2849	repeat protein
BUW91_RS13415	COG5444	nuclease activity
BUW91_RS13430	COG0534	Mate efflux family protein
BUW91_RS13435	COG1566	PFAM secretion protein HlyD family protein
BUW91_RS13445	COG1846	Transcriptional regulator
BUW91_RS13450	COG0708	Exodeoxyribonuclease III
BUW91_RS13465	COG0673	inositol 2-dehydrogenase activity
BUW91_RS13470	COG1349	DNA-binding transcription factor activity
BUW91_RS13475	COG3853	Toxic anion resistance protein (TelA)
BUW91_RS13485	COG2310	stress, protein
BUW91_RS13490	COG2310	stress, protein
BUW91_RS13495	COG2310	stress, protein
BUW91_RS13500	COG0737	Belongs to the 5'-nucleotidase family
BUW91_RS13520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_RS13525	COG1131	(ABC) transporter
BUW91_RS13535	COG2084	Dehydrogenase
BUW91_RS13540	COG1278	Cold shock
BUW91_RS13545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS13555	COG0028	Belongs to the TPP enzyme family
BUW91_RS13560	COG1278	Cold shock
BUW91_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS13600	COG0427	acetyl-CoA hydrolase
BUW91_RS13605	COG3279	Response regulator of the LytR AlgR family
BUW91_RS13610	COG2323	membrane
BUW91_RS13615	COG2814	Major facilitator Superfamily
BUW91_RS13620	COG1388	LysM domain
BUW91_RS13620	COG3584	3D domain protein
BUW91_RS13625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BUW91_RS13650	COG3340	Belongs to the peptidase S51 family
BUW91_RS13665	COG0277	FAD linked oxidase domain protein
BUW91_RS13695	COG2318	DinB family
BUW91_RS13705	COG0579	oxidoreductase
BUW91_RS13735	COG0488	(ABC) transporter
BUW91_RS13740	COG1486	melibiose metabolic process
BUW91_RS13745	COG0395	ABC-type sugar transport system, permease component
BUW91_RS13750	COG1175	transmembrane transport
BUW91_RS13755	COG1653	transport
BUW91_RS13760	COG1609	Transcriptional regulator
BUW91_RS13780	COG1929	Belongs to the glycerate kinase type-1 family
BUW91_RS13785	COG2610	gluconate transmembrane transporter activity
BUW91_RS13790	COG3835	regulator
BUW91_RS13795	COG1454	alcohol dehydrogenase
BUW91_RS13800	COG3152	Membrane
BUW91_RS13815	COG0492	ferredoxin-NADP+ reductase activity
BUW91_RS13825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS13830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS13855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_RS13865	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BUW91_RS13880	COG2390	Transcriptional regulator
BUW91_RS13910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BUW91_RS13915	COG0501	Belongs to the peptidase M48B family
BUW91_RS13920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS13925	COG1742	UPF0060 membrane protein
BUW91_RS13980	COG2391	methyltransferase activity
BUW91_RS13995	COG1979	alcohol dehydrogenase
BUW91_RS14000	COG0583	DNA-binding transcription factor activity
BUW91_RS14010	COG0456	acetyltransferase
BUW91_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS14045	COG1063	alcohol dehydrogenase
BUW91_RS14070	COG0025	NhaP-type Na H and K H
BUW91_RS14075	COG1253	flavin adenine dinucleotide binding
BUW91_RS14100	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS14110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_RS14120	COG0747	negative chemotaxis
BUW91_RS14130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS14150	COG1525	nuclease
BUW91_RS14160	COG0579	oxidoreductase
BUW91_RS14165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BUW91_RS14170	COG0561	phosphatase activity
BUW91_RS14185	COG0668	transmembrane transport
BUW91_RS14215	COG2309	aminopeptidase activity
BUW91_RS14220	COG1414	Transcriptional regulator
BUW91_RS14230	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BUW91_RS14235	COG0277	FAD linked oxidase domain protein
BUW91_RS14240	COG0247	lactate metabolic process
BUW91_RS14245	COG0277	FAD linked oxidase domain protein
BUW91_RS14250	COG1620	l-lactate permease
BUW91_RS14270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BUW91_RS14275	COG1131	(ABC) transporter
BUW91_RS14295	COG1595	DNA-templated transcription, initiation
BUW91_RS14315	COG4682	membrane
BUW91_RS14330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS14335	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS14340	COG0598	Magnesium transport protein CorA
BUW91_RS14345	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUW91_RS14355	COG2323	membrane
BUW91_RS14360	COG1876	peptidase activity
BUW91_RS14375	COG5002	protein histidine kinase activity
BUW91_RS14380	COG0745	RESPONSE REGULATOR receiver
BUW91_RS14400	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_RS14405	COG0567	Dehydrogenase, E1 component
BUW91_RS14415	COG2814	Major facilitator Superfamily
BUW91_RS14420	COG1764	response to oxidative stress
BUW91_RS14430	COG2311	Membrane
BUW91_RS14490	COG0347	Belongs to the P(II) protein family
BUW91_RS14495	COG0004	ammonium transporteR
BUW91_RS14500	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BUW91_RS14515	COG0596	Alpha beta hydrolase
BUW91_RS14535	COG0456	acetyltransferase
BUW91_RS14535	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_RS14540	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS14580	COG4604	ABC transporter, ATP-binding protein
BUW91_RS14585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS14590	COG1492	cobalamin metabolic process
BUW91_RS14600	COG0531	amino acid
BUW91_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS14615	COG2404	hydrolase activity, acting on ester bonds
BUW91_RS14630	COG1609	Transcriptional regulator
BUW91_RS14640	COG2271	Major facilitator Superfamily
BUW91_RS14645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BUW91_RS14660	COG1233	COG1233 Phytoene dehydrogenase and related
BUW91_RS14665	COG0463	Glycosyl transferase, family 2
BUW91_RS14710	COG0804	urea catabolic process
BUW91_RS14720	COG0831	urea catabolic process
BUW91_RS14725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BUW91_RS14730	COG1388	LysM domain
BUW91_RS14730	COG0791	NLP P60 protein
BUW91_RS14735	COG3584	3D domain protein
BUW91_RS14735	COG1388	LysM domain
BUW91_RS14740	COG0778	Nitroreductase
BUW91_RS14745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUW91_RS14750	COG0586	Pfam SNARE associated Golgi protein
BUW91_RS14760	COG0400	carboxylic ester hydrolase activity
BUW91_RS14765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_RS14770	COG2244	polysaccharide biosynthetic process
BUW91_RS14775	COG0697	spore germination
BUW91_RS14780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS14800	COG1132	(ABC) transporter
BUW91_RS14825	COG4195	phage-related replication protein
BUW91_RS14835	COG0783	Belongs to the Dps family
BUW91_RS14845	COG5577	PFAM Coat F domain
BUW91_RS14850	COG1253	flavin adenine dinucleotide binding
BUW91_RS14865	COG0517	IMP dehydrogenase activity
BUW91_RS14865	COG0516	GMP reductase activity
BUW91_RS14875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_RS14875	COG0723	plastoquinol--plastocyanin reductase activity
BUW91_RS14890	COG0287	Prephenate dehydrogenase
BUW91_RS14900	COG1605	Chorismate mutase
BUW91_RS14900	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUW91_RS14910	COG2059	Chromate
BUW91_RS14915	COG2059	Chromate
BUW91_RS14925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BUW91_RS14930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_RS14935	COG2508	Transcriptional regulator
BUW91_RS14940	COG0011	TIGRFAM Protein of
BUW91_RS14945	COG1388	LysM domain
BUW91_RS14945	COG0791	NLP P60 protein
BUW91_RS14950	COG0753	catalase activity
BUW91_RS14960	COG0733	neurotransmitter:sodium symporter activity
BUW91_RS15005	COG0730	response to heat
BUW91_RS15010	COG1902	pentaerythritol trinitrate reductase activity
BUW91_RS15025	COG2205	protein histidine kinase activity
BUW91_RS15035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BUW91_RS15065	COG0640	Transcriptional regulator
BUW91_RS15075	COG0778	Nitroreductase
BUW91_RS15090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BUW91_RS15095	COG4991	sh3 domain protein
BUW91_RS15095	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_RS15095	COG3103	Sh3 type 3 domain protein
BUW91_RS15100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BUW91_RS15105	COG2002	toxin-antitoxin pair type II binding
BUW91_RS15110	COG2318	DinB family
BUW91_RS15115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BUW91_RS15125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BUW91_RS15130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS15150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS15155	COG1597	lipid kinase activity
BUW91_RS15165	COG0372	Belongs to the citrate synthase family
BUW91_RS15170	COG0583	DNA-binding transcription factor activity
BUW91_RS15175	COG0697	spore germination
BUW91_RS15180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS15200	COG2202	Pas domain
BUW91_RS15200	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS15205	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS15240	COG2261	transglycosylase associated protein
BUW91_RS15250	COG0740	serine-type endopeptidase activity
BUW91_RS15265	COG1027	Aspartate ammonia-lyase
BUW91_RS15270	COG0252	asparaginase activity
BUW91_RS15275	COG1396	sequence-specific DNA binding
BUW91_RS15290	COG0640	Transcriptional regulator
BUW91_RS15310	COG0531	amino acid
BUW91_RS15315	COG1959	2 iron, 2 sulfur cluster binding
BUW91_RS15335	COG0281	malic enzyme
BUW91_RS15340	COG2746	aminoglycoside 3-N-acetyltransferase activity
BUW91_RS15350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS15355	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS15370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BUW91_RS15380	COG0477	Major facilitator Superfamily
BUW91_RS15385	COG1846	Transcriptional regulator
BUW91_RS15390	COG0789	Transcriptional regulator
BUW91_RS15395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS15430	COG1819	glycosyl
BUW91_RS15450	COG1902	pentaerythritol trinitrate reductase activity
BUW91_RS15460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_RS15475	COG2814	Major facilitator Superfamily
BUW91_RS15485	COG1228	amidohydrolase
BUW91_RS15495	COG1316	TRANSCRIPTIONal
BUW91_RS15500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BUW91_RS15595	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS15605	COG0531	amino acid
BUW91_RS15620	COG3764	Sortase (surface protein transpeptidase)
BUW91_RS15625	COG0730	response to heat
BUW91_RS15635	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BUW91_RS15645	COG2130	NADP-dependent
BUW91_RS15670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS15685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BUW91_RS15695	COG0501	Belongs to the peptidase M48B family
BUW91_RS15730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BUW91_RS15730	COG0131	Imidazoleglycerol-phosphate dehydratase
BUW91_RS15745	COG2076	Multidrug Resistance protein
BUW91_RS15750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BUW91_RS15755	COG1278	Cold shock
BUW91_RS15760	COG2323	membrane
BUW91_RS15770	COG2910	NAD(P)H-binding
BUW91_RS15800	COG4607	ABC-type enterochelin transport system periplasmic component
BUW91_RS15805	COG4604	ABC transporter, ATP-binding protein
BUW91_RS15810	COG4605	iron ion homeostasis
BUW91_RS15815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS15820	COG3773	Cell wall hydrolase
BUW91_RS15840	COG1063	alcohol dehydrogenase
BUW91_RS15845	COG3775	system Galactitol-specific IIC component
BUW91_RS15850	COG3414	Phosphotransferase system galactitol-specific IIB component
BUW91_RS15855	COG3414	Phosphotransferase system galactitol-specific IIB component
BUW91_RS15870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS15875	COG0681	Belongs to the peptidase S26 family
BUW91_RS15905	COG1349	DNA-binding transcription factor activity
BUW91_RS15920	COG1193	negative regulation of DNA recombination
BUW91_RS15930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BUW91_RS15940	COG0861	Integral membrane protein TerC family
BUW91_RS15945	COG1609	Transcriptional regulator
BUW91_RS15950	COG1959	2 iron, 2 sulfur cluster binding
BUW91_RS16010	COG3773	Cell wall hydrolase
BUW91_RS16015	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUW91_RS16045	COG3546	catalase activity
BUW91_RS16065	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS16070	COG2207	Transcriptional regulator
BUW91_RS16070	COG1917	Cupin 2, conserved barrel domain protein
BUW91_RS16075	COG2203	Gaf domain
BUW91_RS16075	COG4585	Histidine kinase
BUW91_RS16095	COG3209	COG3209 Rhs family protein
BUW91_RS16115	COG1819	glycosyl
BUW91_RS16120	COG0456	acetyltransferase
BUW91_RS16135	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BUW91_RS16145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BUW91_RS16165	COG0346	lactoylglutathione lyase activity
BUW91_RS16170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BUW91_RS16185	COG1136	(ABC) transporter
BUW91_RS16190	COG0577	efflux transmembrane transporter activity
BUW91_RS16195	COG3850	Histidine kinase
BUW91_RS16195	COG5002	protein histidine kinase activity
BUW91_RS16220	COG5002	protein histidine kinase activity
BUW91_RS16225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS16230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BUW91_RS16255	COG4989	oxidoreductase activity
BUW91_RS16265	COG0697	spore germination
BUW91_RS16270	COG1917	Cupin 2, conserved barrel domain protein
BUW91_RS16270	COG2207	Transcriptional regulator
BUW91_RS16345	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BUW91_RS16355	COG0583	DNA-binding transcription factor activity
BUW91_RS16365	COG1301	dicarboxylic acid transport
BUW91_RS16370	COG2824	Alkylphosphonate utilization operon protein PhnA
BUW91_RS16400	COG0405	Gamma-glutamyltransferase
BUW91_RS16420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_RS16425	COG4521	taurine ABC transporter
BUW91_RS16430	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BUW91_RS16435	COG2175	clavaminate synthase activity
BUW91_RS16440	COG0477	Major facilitator Superfamily
BUW91_RS16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS16470	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS16475	COG1063	alcohol dehydrogenase
BUW91_RS16480	COG0745	RESPONSE REGULATOR receiver
BUW91_RS16485	COG0642	Histidine kinase
BUW91_RS16490	COG1136	(ABC) transporter
BUW91_RS16495	COG0577	efflux transmembrane transporter activity
BUW91_RS16505	COG0412	Dienelactone hydrolase
BUW91_RS16510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS16525	COG0730	response to heat
BUW91_RS16530	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_RS16535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_RS16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS16540	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_RS16540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_RS16555	COG2210	Belongs to the sulfur carrier protein TusA family
BUW91_RS16560	COG0425	Belongs to the sulfur carrier protein TusA family
BUW91_RS16565	COG1937	Protein conserved in bacteria
BUW91_RS16585	COG0583	DNA-binding transcription factor activity
BUW91_RS16600	COG2188	Transcriptional regulator
BUW91_RS16610	COG2723	6-phospho-beta-galactosidase activity
BUW91_RS16635	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS16650	COG0583	DNA-binding transcription factor activity
BUW91_RS16655	COG2814	Major facilitator Superfamily
BUW91_RS16660	COG0346	lactoylglutathione lyase activity
BUW91_RS16675	COG2723	6-phospho-beta-galactosidase activity
BUW91_RS16680	COG5001	Diguanylate cyclase
BUW91_RS16680	COG3300	MHYT domain
BUW91_RS16685	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BUW91_RS16700	COG0778	Nitroreductase
BUW91_RS16705	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS16725	COG1704	LemA family
BUW91_RS16745	COG1733	regulation of RNA biosynthetic process
BUW91_RS16750	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_RS16755	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_RS16760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BUW91_RS16775	COG2304	oxidoreductase activity
BUW91_RS16785	COG0346	lactoylglutathione lyase activity
BUW91_RS16790	COG2808	Putative FMN-binding domain
BUW91_RS16825	COG4807	Protein conserved in bacteria
BUW91_RS16835	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BUW91_RS16845	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS16850	COG1278	Cold shock
BUW91_RS16855	COG1278	Cold shock
BUW91_RS16870	COG0747	negative chemotaxis
BUW91_RS16875	COG0601	transmembrane transport
BUW91_RS16880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BUW91_RS16885	COG0444	Belongs to the ABC transporter superfamily
BUW91_RS16890	COG4608	Belongs to the ABC transporter superfamily
BUW91_RS16900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUW91_RS16905	COG1301	dicarboxylic acid transport
BUW91_RS16920	COG0477	Major facilitator Superfamily
BUW91_RS16965	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_RS16975	COG2211	Major facilitator Superfamily
BUW91_RS16980	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BUW91_RS16985	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BUW91_RS16990	COG1691	(AIR) carboxylase
BUW91_RS16995	COG1606	tRNA processing
BUW91_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS17010	COG1904	glucuronate isomerase
BUW91_RS17085	COG0561	phosphatase activity
BUW91_RS17095	COG2312	Erythromycin esterase
BUW91_RS17110	COG2329	Antibiotic biosynthesis monooxygenase
BUW91_RS17150	COG3655	Transcriptional regulator
BUW91_RS17160	COG0583	DNA-binding transcription factor activity
BUW91_RS17165	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS17180	COG1609	Transcriptional regulator
BUW91_RS17185	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_RS17190	COG0673	inositol 2-dehydrogenase activity
BUW91_RS17210	COG3718	enzyme involved in inositol metabolism
BUW91_RS17215	COG3962	Belongs to the TPP enzyme family
BUW91_RS17220	COG1349	DNA-binding transcription factor activity
BUW91_RS17225	COG0191	fructose-bisphosphate aldolase activity
BUW91_RS17230	COG1082	Xylose isomerase domain protein TIM barrel
BUW91_RS17235	COG2814	Major facilitator Superfamily
BUW91_RS17255	COG0789	Transcriptional regulator
BUW91_RS17270	COG0662	Cupin 2, conserved barrel domain protein
BUW91_RS17290	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS17295	COG1278	Cold shock
BUW91_RS17300	COG1876	peptidase activity
BUW91_RS17320	COG0598	Magnesium transport protein CorA
BUW91_RS17325	COG1366	Belongs to the anti-sigma-factor antagonist family
BUW91_RS17335	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS17355	COG4335	DNA alkylation repair
BUW91_RS17360	COG0454	-acetyltransferase
BUW91_RS17380	COG2814	Major facilitator Superfamily
BUW91_RS17385	COG3848	Pyruvate phosphate dikinase
BUW91_RS17385	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_RS17390	COG3848	Pyruvate phosphate dikinase
BUW91_RS17390	COG0574	Belongs to the PEP-utilizing enzyme family
BUW91_RS17405	COG2186	Transcriptional regulator
BUW91_RS17425	COG3619	membrane
BUW91_RS17430	COG1349	DNA-binding transcription factor activity
BUW91_RS17435	COG0561	phosphatase activity
BUW91_RS17445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_RS17460	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS17485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUW91_RS17500	COG2814	Major facilitator Superfamily
BUW91_RS17505	COG2160	L-arabinose isomerase activity
BUW91_RS17520	COG1609	Transcriptional regulator
BUW91_RS17525	COG1078	dGTPase activity
BUW91_RS17545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_RS17550	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_RS17555	COG1918	ferrous iron import across plasma membrane
BUW91_RS17555	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BUW91_RS17580	COG1846	Transcriptional regulator
BUW91_RS17615	COG0697	spore germination
BUW91_RS17620	COG0791	NLP P60 protein
BUW91_RS17620	COG1388	LysM domain
BUW91_RS17625	COG2258	MOSC domain
BUW91_RS17630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BUW91_RS17665	COG4974	Belongs to the 'phage' integrase family
BUW91_RS17705	COG1309	transcriptional regulator
BUW91_RS17710	COG3844	kynureninase activity
BUW91_RS17715	COG1113	amino acid transport
BUW91_RS17720	COG3483	tryptophan 2,3-dioxygenase activity
BUW91_RS17725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BUW91_RS17730	COG1942	4-Oxalocrotonate Tautomerase
BUW91_RS17760	COG0251	oxidation-reduction process
BUW91_RS17775	COG0431	NADPH-dependent FMN reductase
BUW91_RS17780	COG0196	riboflavin kinase activity
BUW91_RS17785	COG2368	4-hydroxyphenylacetate
BUW91_RS17805	COG0789	Transcriptional regulator
BUW91_RS17840	COG5646	InterPro IPR014922
BUW91_RS17845	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BUW91_RS17880	COG2258	MOSC domain
BUW91_RS17895	COG0477	Major facilitator Superfamily
BUW91_RS17900	COG0583	DNA-binding transcription factor activity
BUW91_RS17905	COG2070	2-Nitropropane dioxygenase
BUW91_RS17910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BUW91_RS17925	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS17955	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS17960	COG2188	Transcriptional regulator
BUW91_RS17970	COG1501	Belongs to the glycosyl hydrolase 31 family
BUW91_RS17980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BUW91_RS17990	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BUW91_RS18000	COG0300	oxidoreductase activity
BUW91_RS18010	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_RS18010	COG0596	Alpha beta hydrolase
BUW91_RS18015	COG1309	transcriptional regulator
BUW91_RS18020	COG1733	regulation of RNA biosynthetic process
BUW91_RS18025	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS18030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BUW91_RS18035	COG2226	methyltransferase
BUW91_RS18050	COG1942	4-Oxalocrotonate Tautomerase
BUW91_RS18055	COG0583	DNA-binding transcription factor activity
BUW91_RS18065	COG1522	sequence-specific DNA binding
BUW91_RS18075	COG2267	carboxylic ester hydrolase activity
BUW91_RS18085	COG1335	isochorismatase
BUW91_RS18095	COG0346	lactoylglutathione lyase activity
BUW91_RS18100	COG2259	Doxx family
BUW91_RS18105	COG0039	L-malate dehydrogenase activity
BUW91_RS18110	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BUW91_RS18115	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
BUW91_RS18135	COG1454	alcohol dehydrogenase
BUW91_RS18135	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS18145	COG4302	ethanolamine ammonia-lyase activity
BUW91_RS18150	COG4303	Ethanolamine ammonia lyase large subunit
BUW91_RS18160	COG4917	ethanolamine utilization protein
BUW91_RS18170	COG3192	ethanolamine utilization protein
BUW91_RS18200	COG1309	transcriptional regulator
BUW91_RS18205	COG2076	Multidrug Resistance protein
BUW91_RS18215	COG0477	Major facilitator Superfamily
BUW91_RS18235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BUW91_RS18245	COG2851	Citrate transporter
BUW91_RS18255	COG0477	Major facilitator Superfamily
BUW91_RS18265	COG0477	Major facilitator Superfamily
BUW91_RS18270	COG1309	transcriptional regulator
BUW91_RS18280	COG2318	DinB family
BUW91_RS18285	COG0156	8-amino-7-oxononanoate synthase activity
BUW91_RS18290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BUW91_RS18305	COG1378	Sugar-specific transcriptional regulator TrmB
BUW91_RS18310	COG0697	spore germination
BUW91_RS18320	COG0583	DNA-binding transcription factor activity
BUW91_RS18360	COG1266	CAAX protease self-immunity
BUW91_RS18385	COG0252	asparaginase activity
BUW91_RS18405	COG1695	Transcriptional regulator
BUW91_RS18410	COG0656	L-ascorbic acid biosynthetic process
BUW91_RS18420	COG0583	DNA-binding transcription factor activity
BUW91_RS18430	COG2814	Major facilitator Superfamily
BUW91_RS18455	COG1309	transcriptional regulator
BUW91_RS18510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BUW91_RS18580	COG3339	Conserved Protein
BUW91_RS18595	COG2207	Transcriptional regulator
BUW91_RS18595	COG3708	Transcriptional regulator
BUW91_RS18610	COG1357	PFAM Pentapeptide repeats (8 copies)
BUW91_RS18620	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS18625	COG1733	regulation of RNA biosynthetic process
BUW91_RS18670	COG0303	'Molybdopterin
BUW91_RS18680	COG0521	Mo-molybdopterin cofactor biosynthetic process
BUW91_RS18685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BUW91_RS18690	COG1079	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS18695	COG4603	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS18700	COG3845	ABC transporter
BUW91_RS18725	COG2828	Protein conserved in bacteria
BUW91_RS18730	COG0583	DNA-binding transcription factor activity
BUW91_RS18735	COG2851	Citrate transporter
BUW91_RS18750	COG0670	Belongs to the BI1 family
BUW91_RS18770	COG0791	NLP P60 protein
BUW91_RS18775	COG2814	Major facilitator Superfamily
BUW91_RS18780	COG1846	Transcriptional regulator
BUW91_RS18800	COG1278	Cold shock
BUW91_RS18815	COG1113	amino acid transport
BUW91_RS18820	COG1113	amino acid transport
BUW91_RS18825	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS18830	COG0506	proline dehydrogenase activity
BUW91_RS18835	COG3878	Protein conserved in bacteria
BUW91_RS18855	COG5001	Diguanylate cyclase
BUW91_RS18855	COG3300	MHYT domain
BUW91_RS18905	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BUW91_RS18910	COG5609	conserved protein (DUF2294)
BUW91_RS18920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUW91_RS18945	COG0454	-acetyltransferase
BUW91_RS18960	COG0789	Transcriptional regulator
BUW91_RS18965	COG0667	Aldo Keto reductase
BUW91_RS18975	COG0789	Transcriptional regulator
BUW91_RS19000	COG1621	beta-fructofuranosidase activity
BUW91_RS19005	COG4980	gas vesicle protein
BUW91_RS19030	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_RS19035	COG0577	efflux transmembrane transporter activity
BUW91_RS19040	COG1136	(ABC) transporter
BUW91_RS19050	COG0642	Histidine kinase
BUW91_RS19065	COG1289	transmembrane transporter activity
BUW91_RS19070	COG1937	Protein conserved in bacteria
BUW91_RS19075	COG3209	COG3209 Rhs family protein
BUW91_RS19085	COG3973	AAA domain
BUW91_RS19090	COG1024	Enoyl-CoA hydratase
BUW91_RS19095	COG1733	regulation of RNA biosynthetic process
BUW91_RS19110	COG2124	cytochrome p450
BUW91_RS19115	COG2259	Doxx family
BUW91_RS19120	COG0463	Glycosyl transferase, family 2
BUW91_RS19130	COG0463	Glycosyl transferase, family 2
BUW91_RS19145	COG0791	NLP P60 protein
BUW91_RS19145	COG1388	LysM domain
BUW91_RS19150	COG0840	transmembrane signaling receptor activity
BUW91_RS19155	COG1846	Transcriptional regulator
BUW91_RS19170	COG0726	polysaccharide deacetylase
BUW91_RS19175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BUW91_RS19190	COG0833	amino acid
BUW91_RS19220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BUW91_RS19225	COG0569	domain protein
BUW91_RS19235	COG1522	sequence-specific DNA binding
BUW91_RS19250	COG0745	RESPONSE REGULATOR receiver
BUW91_RS19255	COG2770	Histidine kinase
BUW91_RS19255	COG2205	protein histidine kinase activity
BUW91_RS19260	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BUW91_RS19265	COG1607	acyl-coa hydrolase
BUW91_RS19270	COG1802	Transcriptional regulator
BUW91_RS19275	COG0697	spore germination
BUW91_RS19285	COG0006	proline dipeptidase activity
BUW91_RS19305	COG2249	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS19310	COG5522	Integral membrane protein (intg_mem_TP0381)
BUW91_RS19315	COG1174	glycine betaine transport
BUW91_RS19320	COG0517	IMP dehydrogenase activity
BUW91_RS19320	COG1125	glycine betaine transport
BUW91_RS19345	COG0395	ABC-type sugar transport system, permease component
BUW91_RS19365	COG1609	Transcriptional regulator
BUW91_RS19370	COG2205	protein histidine kinase activity
BUW91_RS19375	COG0730	response to heat
BUW91_RS19380	COG1301	dicarboxylic acid transport
BUW91_RS19395	COG0753	catalase activity
BUW91_RS19420	COG1368	sulfuric ester hydrolase activity
BUW91_RS19430	COG0697	spore germination
BUW91_RS19450	COG1113	amino acid transport
BUW91_RS19455	COG5505	Protein of unknown function (DUF819)
BUW91_RS19460	COG1309	transcriptional regulator
BUW91_RS19470	COG0583	DNA-binding transcription factor activity
BUW91_RS19475	COG0730	response to heat
BUW91_RS19480	COG1247	-acetyltransferase
BUW91_RS19485	COG2910	NAD(P)H-binding
BUW91_RS19490	COG1285	pathogenesis
BUW91_RS19495	COG2226	methyltransferase
BUW91_RS19500	COG4195	phage-related replication protein
BUW91_RS19505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BUW91_RS19520	COG1113	amino acid transport
BUW91_RS19550	COG0463	Glycosyl transferase, family 2
BUW91_RS19580	COG2514	catechol 2,3-dioxygenase activity
BUW91_RS19600	COG1280	lysine exporter protein (LysE YggA)
BUW91_RS19620	COG0668	transmembrane transport
BUW91_RS19625	COG2340	Cysteine-rich secretory protein family
BUW91_RS19630	COG1253	flavin adenine dinucleotide binding
BUW91_RS19640	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BUW91_RS19645	COG0589	response to stress
BUW91_RS19650	COG0205	6-phosphofructokinase activity
BUW91_RS19655	COG1388	LysM domain
BUW91_RS19655	COG0791	NLP P60 protein
BUW91_RS19665	COG0432	Pfam Uncharacterised protein family UPF0047
BUW91_RS19670	COG0697	spore germination
BUW91_RS19675	COG0814	amino acid
BUW91_RS19700	COG1131	(ABC) transporter
BUW91_RS19715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BUW91_RS19730	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_RS19740	COG1131	(ABC) transporter
BUW91_RS19755	COG0706	membrane insertase activity
BUW91_RS19765	COG1263	PTS System
BUW91_RS19765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS19770	COG3711	transcriptional antiterminator
BUW91_RS19775	COG2190	(PTS) system
BUW91_RS19780	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BUW91_RS19795	COG0772	Belongs to the SEDS family
BUW91_RS19800	COG0659	secondary active sulfate transmembrane transporter activity
BUW91_RS19805	COG0813	purine-nucleoside phosphorylase activity
BUW91_RS19815	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS19820	COG4326	sporulation control protein
BUW91_RS19825	COG0515	serine threonine protein kinase
BUW91_RS19825	COG2815	serine threonine protein kinase
BUW91_RS19850	COG4479	Belongs to the UPF0346 family
BUW91_RS19855	COG3594	Acyltransferase
BUW91_RS19875	COG0456	acetyltransferase
BUW91_RS19880	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_RS19885	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUW91_RS19890	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_RS19895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_RS19900	COG1301	dicarboxylic acid transport
BUW91_RS19910	COG4191	Histidine kinase
BUW91_RS19935	COG2755	lipolytic protein G-D-S-L family
BUW91_RS19940	COG1999	signal sequence binding
BUW91_RS19950	COG1307	EDD domain protein, DegV family
BUW91_RS19960	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BUW91_RS19970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BUW91_RS19975	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BUW91_RS19980	COG0788	formyltetrahydrofolate deformylase activity
BUW91_RS20010	COG0076	glutamate decarboxylase activity
BUW91_RS20030	COG0415	Belongs to the DNA photolyase family
BUW91_RS20035	COG3852	Histidine kinase
BUW91_RS20050	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS20065	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BUW91_RS20075	COG4846	Membrane protein involved in cytochrome C biogenesis
BUW91_RS20080	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BUW91_RS20085	COG0785	Cytochrome C biogenesis protein
BUW91_RS20095	COG1132	(ABC) transporter
BUW91_RS20100	COG1132	(ABC) transporter
BUW91_RS20120	COG4224	UPF0291 protein
BUW91_RS20125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BUW91_RS20150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BUW91_RS20155	COG0531	amino acid
BUW91_RS20165	COG0174	glutamine synthetase
BUW91_RS20170	COG0789	Transcriptional regulator
BUW91_RS20175	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BUW91_RS20180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BUW91_RS20185	COG2860	membrane
BUW91_RS20190	COG0464	growth
BUW91_RS20210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BUW91_RS20215	COG0531	amino acid
BUW91_RS20225	COG4550	Control of competence regulator ComK, YlbF/YmcA
BUW91_RS20230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUW91_RS20235	COG1013	pyruvate-flavodoxin oxidoreductase activity
BUW91_RS20240	COG0674	pyruvate-flavodoxin oxidoreductase activity
BUW91_RS20240	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BUW91_RS20250	COG2359	stage V sporulation protein S
BUW91_RS20255	COG1692	metallophosphoesterase
BUW91_RS20265	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BUW91_RS20270	COG1546	Belongs to the CinA family
BUW91_RS20270	COG1058	Belongs to the CinA family
BUW91_RS20275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BUW91_RS20280	COG1426	Protein conserved in bacteria
BUW91_RS20295	COG0300	oxidoreductase activity
BUW91_RS20300	COG0612	Peptidase, M16
BUW91_RS20305	COG0612	Peptidase, M16
BUW91_RS20310	COG1079	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS20315	COG4603	Belongs to the binding-protein-dependent transport system permease family
BUW91_RS20320	COG3845	ABC transporter
BUW91_RS20325	COG1744	ABC transporter substrate-binding protein PnrA-like
BUW91_RS20330	COG2188	Transcriptional regulator
BUW91_RS20335	COG4980	gas vesicle protein
BUW91_RS20335	COG1674	ftsk spoiiie
BUW91_RS20345	COG0740	serine-type endopeptidase activity
BUW91_RS20360	COG0527	aspartate kinase activity
BUW91_RS20365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BUW91_RS20370	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUW91_RS20375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_RS20380	COG1873	PFAM PRC-barrel domain
BUW91_RS20385	COG0612	Peptidase, M16
BUW91_RS20390	COG0726	polysaccharide deacetylase
BUW91_RS20395	COG1185	polyribonucleotide nucleotidyltransferase activity
BUW91_RS20400	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BUW91_RS20405	COG0196	riboflavin kinase activity
BUW91_RS20415	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BUW91_RS20420	COG1550	Protein conserved in bacteria
BUW91_RS20430	COG1358	cellular component organization or biogenesis
BUW91_RS20435	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BUW91_RS20440	COG0195	Participates in both transcription termination and antitermination
BUW91_RS20445	COG0779	Required for maturation of 30S ribosomal subunits
BUW91_RS20450	COG2176	DNA-directed DNA polymerase activity
BUW91_RS20455	COG0442	prolyl-tRNA aminoacylation
BUW91_RS20460	COG0750	zinc metalloprotease
BUW91_RS20470	COG4589	Belongs to the CDS family
BUW91_RS20480	COG0233	cytoplasmic translational termination
BUW91_RS20490	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BUW91_RS20505	COG1191	sigma factor activity
BUW91_RS20510	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BUW91_RS20515	COG0835	chemotaxis
BUW91_RS20520	COG0643	Histidine kinase
BUW91_RS20520	COG2198	Histidine kinase
BUW91_RS20525	COG2201	protein-glutamate methylesterase activity
BUW91_RS20530	COG0455	bacterial-type flagellum organization
BUW91_RS20535	COG1419	protein localization to endoplasmic reticulum
BUW91_RS20540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BUW91_RS20550	COG1684	flagellar biosynthetic protein fliR
BUW91_RS20555	COG1987	bacterial-type flagellum assembly
BUW91_RS20560	COG1338	Plays a role in the flagellum-specific transport system
BUW91_RS20565	COG3190	flagellar
BUW91_RS20570	COG2201	protein-glutamate methylesterase activity
BUW91_RS20575	COG1776	CheC inhibitor of MCP methylation
BUW91_RS20575	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_RS20580	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_RS20590	COG1582	Flagellar protein (FlbD)
BUW91_RS20595	COG4786	Flagellar basal body rod
BUW91_RS20600	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BUW91_RS20615	COG2882	bacterial-type flagellum organization
BUW91_RS20620	COG1157	protein secretion by the type III secretion system
BUW91_RS20625	COG1317	bacterial-type flagellum organization
BUW91_RS20630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BUW91_RS20635	COG1766	The M ring may be actively involved in energy transduction
BUW91_RS20640	COG1677	Flagellar hook-basal body complex protein FliE
BUW91_RS20645	COG1558	bacterial-type flagellum-dependent cell motility
BUW91_RS20650	COG1815	bacterial-type flagellum-dependent cell motility
BUW91_RS20655	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUW91_RS20660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BUW91_RS20670	COG4974	Belongs to the 'phage' integrase family
BUW91_RS20675	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BUW91_RS20680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BUW91_RS20685	COG0758	DNA mediated transformation
BUW91_RS20690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BUW91_RS20695	COG0045	succinate-CoA ligase (ADP-forming) activity
BUW91_RS20715	COG0335	large ribosomal subunit rRNA binding
BUW91_RS20725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BUW91_RS20735	COG1837	Belongs to the UPF0109 family
BUW91_RS20740	COG0228	four-way junction DNA binding
BUW91_RS20745	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BUW91_RS20755	COG0552	protein localization to endoplasmic reticulum
BUW91_RS20760	COG1196	nuclear chromosome segregation
BUW91_RS20765	COG0571	ribonuclease III activity
BUW91_RS20775	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS20780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BUW91_RS20785	COG0416	fatty acid biosynthetic process
BUW91_RS20790	COG1349	DNA-binding transcription factor activity
BUW91_RS20795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BUW91_RS20800	COG1760	l-serine dehydratase
BUW91_RS20805	COG1760	l-serine dehydratase
BUW91_RS20820	COG1302	Protein conserved in bacteria
BUW91_RS20825	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BUW91_RS20835	COG1564	THIamine pyrophosphokinase
BUW91_RS20840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BUW91_RS20845	COG1162	GTPase activity
BUW91_RS20850	COG2815	serine threonine protein kinase
BUW91_RS20850	COG0515	serine threonine protein kinase
BUW91_RS20855	COG0631	protein serine/threonine phosphatase activity
BUW91_RS20865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUW91_RS20865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BUW91_RS20870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BUW91_RS20880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BUW91_RS20885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BUW91_RS20890	COG1758	RNA polymerase activity
BUW91_RS20895	COG0194	GDP metabolic process
BUW91_RS20900	COG2052	Domain of unknown function (DUF370)
BUW91_RS20905	COG1561	YicC-like family, N-terminal region
BUW91_RS20910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BUW91_RS20920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BUW91_RS20955	COG0540	Belongs to the ATCase OTCase family
BUW91_RS20965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BUW91_RS20970	COG0564	pseudouridine synthase activity
BUW91_RS20975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BUW91_RS20990	COG3599	regulation of cell shape
BUW91_RS20995	COG2302	S4 RNA-binding domain
BUW91_RS21000	COG0762	integral membrane protein
BUW91_RS21005	COG1799	cell septum assembly
BUW91_RS21010	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BUW91_RS21015	COG1496	oxidoreductase activity
BUW91_RS21020	COG1873	PFAM PRC-barrel domain
BUW91_RS21025	COG1191	sigma factor activity
BUW91_RS21030	COG1191	sigma factor activity
BUW91_RS21040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BUW91_RS21045	COG0849	cell division
BUW91_RS21050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BUW91_RS21055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BUW91_RS21060	COG0772	Belongs to the SEDS family
BUW91_RS21065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BUW91_RS21070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUW91_RS21075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BUW91_RS21080	COG0768	penicillin binding
BUW91_RS21085	COG0768	penicillin binding
BUW91_RS21090	COG4839	cell division protein FtsL
BUW91_RS21100	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BUW91_RS21110	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BUW91_RS21115	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUW91_RS21120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BUW91_RS21125	COG0439	Biotin carboxylase
BUW91_RS21130	COG0454	-acetyltransferase
BUW91_RS21140	COG1024	Enoyl-CoA hydratase
BUW91_RS21145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BUW91_RS21150	COG1399	metal-binding, possibly nucleic acid-binding protein
BUW91_RS21155	COG1323	Belongs to the UPF0348 family
BUW91_RS21160	COG3480	Lon protease (S16) C-terminal proteolytic domain
BUW91_RS21165	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_RS21170	COG3314	Sporulation integral membrane protein YlbJ
BUW91_RS21175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BUW91_RS21180	COG0742	ribosomal rna small subunit methyltransferase
BUW91_RS21190	COG4471	UPF0298 protein
BUW91_RS21200	COG3679	Belongs to the UPF0342 family
BUW91_RS21220	COG4347	Protein of unknown function (DUF1405)
BUW91_RS21230	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BUW91_RS21245	COG5582	Belongs to the UPF0302 family
BUW91_RS21250	COG0457	Tetratricopeptide repeat
BUW91_RS21260	COG0287	Prephenate dehydrogenase
BUW91_RS21270	COG0159	tryptophan synthase activity
BUW91_RS21280	COG0135	phosphoribosylanthranilate isomerase activity
BUW91_RS21285	COG0134	indole-3-glycerol-phosphate synthase activity
BUW91_RS21290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BUW91_RS21300	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BUW91_RS21305	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BUW91_RS21310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BUW91_RS21315	COG0105	UTP biosynthetic process
BUW91_RS21320	COG0142	geranyltranstransferase activity
BUW91_RS21325	COG2226	methyltransferase
BUW91_RS21330	COG0142	geranyltranstransferase activity
BUW91_RS21340	COG0302	gtp cyclohydrolase
BUW91_RS21345	COG0776	regulation of translation
BUW91_RS21350	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BUW91_RS21385	COG2271	Major facilitator Superfamily
BUW91_RS21390	COG1304	FMN binding
BUW91_RS21395	COG0539	negative regulation of cytoplasmic translation
BUW91_RS21405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BUW91_RS21415	COG2959	enzyme of heme biosynthesis
BUW91_RS21420	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_RS21420	COG3773	Cell wall hydrolase
BUW91_RS21425	COG2339	peptidase activity
BUW91_RS21430	COG0252	asparaginase activity
BUW91_RS21435	COG0492	ferredoxin-NADP+ reductase activity
BUW91_RS21440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BUW91_RS21445	COG4862	establishment of competence for transformation
BUW91_RS21450	COG0789	Transcriptional regulator
BUW91_RS21455	COG1408	metallophosphoesterase
BUW91_RS21470	COG1266	CAAX protease self-immunity
BUW91_RS21475	COG0514	ATP-dependent DNA helicase (RecQ)
BUW91_RS21485	COG1141	Ferredoxin
BUW91_RS21490	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BUW91_RS21495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BUW91_RS21500	COG0739	heme binding
BUW91_RS21505	COG5002	protein histidine kinase activity
BUW91_RS21510	COG0745	RESPONSE REGULATOR receiver
BUW91_RS21515	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUW91_RS21520	COG1333	cytochrome c biogenesis protein
BUW91_RS21525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS21530	COG1187	pseudouridine synthase activity
BUW91_RS21535	COG0700	Nucleoside recognition
BUW91_RS21540	COG2715	membrane protein required for spore maturation
BUW91_RS21545	COG1686	Belongs to the peptidase S11 family
BUW91_RS21550	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BUW91_RS21555	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BUW91_RS21565	COG1547	Domain of unknown function (DUF309)
BUW91_RS21575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BUW91_RS21580	COG4086	secreted protein
BUW91_RS21590	COG0697	spore germination
BUW91_RS21605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BUW91_RS21640	COG1686	Belongs to the peptidase S11 family
BUW91_RS21655	COG4974	Belongs to the 'phage' integrase family
BUW91_RS21665	COG0735	belongs to the Fur family
BUW91_RS21670	COG1300	Membrane
BUW91_RS21675	COG0494	nUDIX hydrolase
BUW91_RS21685	COG0667	Aldo Keto reductase
BUW91_RS21695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BUW91_RS21700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BUW91_RS21710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_RS21715	COG1073	alpha beta
BUW91_RS21730	COG0300	oxidoreductase activity
BUW91_RS21735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS21740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_RS21745	COG1902	pentaerythritol trinitrate reductase activity
BUW91_RS21755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BUW91_RS21760	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS21765	COG2508	Transcriptional regulator
BUW91_RS21785	COG0167	dihydroorotate dehydrogenase activity
BUW91_RS21785	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BUW91_RS21790	COG0493	'glutamate synthase
BUW91_RS21795	COG2195	Cleaves the N-terminal amino acid of tripeptides
BUW91_RS21800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BUW91_RS21805	COG0346	lactoylglutathione lyase activity
BUW91_RS21810	COG1376	ErfK ybiS ycfS ynhG family protein
BUW91_RS21815	COG4129	membrane
BUW91_RS21820	COG1126	abc transporter atp-binding protein
BUW91_RS21825	COG0765	amino acid transport
BUW91_RS21830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BUW91_RS21840	COG1703	isobutyryl-CoA mutase activity
BUW91_RS21845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS21845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS21850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS21850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS21855	COG0508	dehydrogenase complex catalyzes the overall conversion of
BUW91_RS21860	COG0022	dehydrogenase e1 component
BUW91_RS21865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BUW91_RS21885	COG0280	phosphate acetyltransferase
BUW91_RS21890	COG3829	transcription factor binding
BUW91_RS21890	COG3290	protein histidine kinase activity
BUW91_RS21900	COG0584	glycerophosphoryl diester phosphodiesterase
BUW91_RS21905	COG3093	addiction module antidote protein HigA
BUW91_RS21910	COG3104	oligopeptide transport
BUW91_RS21915	COG0745	RESPONSE REGULATOR receiver
BUW91_RS21920	COG0750	zinc metalloprotease
BUW91_RS21925	COG0497	DNA recombination
BUW91_RS21935	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BUW91_RS21950	COG1722	exodeoxyribonuclease VII activity
BUW91_RS21960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BUW91_RS21965	COG1302	Protein conserved in bacteria
BUW91_RS21970	COG0439	Biotin carboxylase
BUW91_RS21975	COG0511	ligase activity, forming carbon-carbon bonds
BUW91_RS22015	COG3854	ATPases associated with a variety of cellular activities
BUW91_RS22025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BUW91_RS22030	COG0006	proline dipeptidase activity
BUW91_RS22035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BUW91_RS22045	COG3872	metal-dependent enzyme
BUW91_RS22055	COG1752	Esterase of the alpha-beta hydrolase superfamily
BUW91_RS22060	COG1321	iron dependent repressor
BUW91_RS22065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_RS22070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_RS22075	COG0095	Lipoate-protein ligase
BUW91_RS22080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_RS22090	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BUW91_RS22095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BUW91_RS22100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUW91_RS22130	COG4970	Tfp pilus assembly protein FimT
BUW91_RS22135	COG4537	Required for transformation and DNA binding
BUW91_RS22140	COG1459	type II secretion system
BUW91_RS22145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BUW91_RS22150	COG1393	Belongs to the ArsC family
BUW91_RS22160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS22175	COG1940	carbohydrate kinase activity
BUW91_RS22180	COG4483	Protein conserved in bacteria
BUW91_RS22185	COG0705	Rhomboid family
BUW91_RS22185	COG0457	Tetratricopeptide repeat
BUW91_RS22195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BUW91_RS22205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BUW91_RS22220	COG0704	Plays a role in the regulation of phosphate uptake
BUW91_RS22230	COG0768	penicillin binding
BUW91_RS22235	COG0477	Major facilitator Superfamily
BUW91_RS22280	COG2814	Major facilitator Superfamily
BUW91_RS22285	COG1388	LysM domain
BUW91_RS22290	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BUW91_RS22295	COG4709	membrane
BUW91_RS22300	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BUW91_RS22305	COG0735	belongs to the Fur family
BUW91_RS22310	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BUW91_RS22315	COG1121	(ABC) transporter
BUW91_RS22325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BUW91_RS22330	COG0513	Belongs to the DEAD box helicase family
BUW91_RS22340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BUW91_RS22345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BUW91_RS22350	COG2384	SAM-dependent methyltransferase
BUW91_RS22355	COG2010	Cytochrome c
BUW91_RS22360	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS22365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BUW91_RS22370	COG0358	DNA primase activity
BUW91_RS22375	COG1671	Belongs to the UPF0178 family
BUW91_RS22380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BUW91_RS22400	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BUW91_RS22405	COG0295	cytidine deaminase activity
BUW91_RS22410	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BUW91_RS22420	COG1480	7TM receptor with intracellular HD hydrolase
BUW91_RS22425	COG1702	phosphate starvation-inducible protein PhoH
BUW91_RS22450	COG1030	water channel activity
BUW91_RS22455	COG1610	YqeY-like protein
BUW91_RS22465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BUW91_RS22470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BUW91_RS22475	COG2264	protein methyltransferase activity
BUW91_RS22490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BUW91_RS22495	COG1420	regulation of RNA biosynthetic process
BUW91_RS22505	COG0481	GTPase activity
BUW91_RS22515	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BUW91_RS22520	COG0268	Binds directly to 16S ribosomal RNA
BUW91_RS22525	COG1466	dna polymerase III delta subunit
BUW91_RS22535	COG0658	competence protein
BUW91_RS22535	COG2333	competence protein COMEC
BUW91_RS22540	COG2131	deaminase
BUW91_RS22545	COG1596	polysaccharide export
BUW91_RS22545	COG1555	photosystem II stabilization
BUW91_RS22550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BUW91_RS22555	COG2226	methyltransferase
BUW91_RS22560	COG0799	negative regulation of ribosome biogenesis
BUW91_RS22565	COG1713	HD superfamily hydrolase involved in NAD metabolism
BUW91_RS22570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BUW91_RS22575	COG1534	Rna-binding protein
BUW91_RS22580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BUW91_RS22585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BUW91_RS22590	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BUW91_RS22600	COG0688	phosphatidylethanolamine metabolic process
BUW91_RS22605	COG1183	phosphatidylcholine synthase activity
BUW91_RS22625	COG0626	cystathionine gamma-synthase activity
BUW91_RS22630	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_RS22635	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BUW91_RS22640	COG2226	methyltransferase
BUW91_RS22655	COG0768	penicillin binding
BUW91_RS22660	COG1335	isochorismatase
BUW91_RS22665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BUW91_RS22670	COG0572	uridine kinase
BUW91_RS22675	COG0826	peptidase U32
BUW91_RS22680	COG0826	peptidase U32
BUW91_RS22685	COG4122	O-methyltransferase activity
BUW91_RS22690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BUW91_RS22695	COG3906	Belongs to the UPF0473 family
BUW91_RS22705	COG4472	Bacterial protein of unknown function (DUF965)
BUW91_RS22715	COG0628	permease
BUW91_RS22730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BUW91_RS22740	COG0482	sulfurtransferase activity
BUW91_RS22745	COG1104	cysteine desulfurase activity
BUW91_RS22750	COG1959	2 iron, 2 sulfur cluster binding
BUW91_RS22755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BUW91_RS22760	COG0581	inorganic phosphate transmembrane transporter activity
BUW91_RS22765	COG0573	inorganic phosphate transmembrane transporter activity
BUW91_RS22770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BUW91_RS22775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BUW91_RS22785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BUW91_RS22790	COG0124	histidyl-tRNA synthetase
BUW91_RS22800	COG0860	N-Acetylmuramoyl-L-alanine amidase
BUW91_RS22805	COG1490	D-aminoacyl-tRNA deacylase activity
BUW91_RS22810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BUW91_RS22815	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BUW91_RS22820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BUW91_RS22820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BUW91_RS22825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUW91_RS22825	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BUW91_RS22835	COG2244	polysaccharide biosynthetic process
BUW91_RS22840	COG2323	membrane
BUW91_RS22850	COG1862	Preprotein translocase
BUW91_RS22855	COG0343	queuine tRNA-ribosyltransferase activity
BUW91_RS22860	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BUW91_RS22870	COG2255	four-way junction helicase activity
BUW91_RS22875	COG0632	four-way junction helicase activity
BUW91_RS22900	COG1388	LysM domain
BUW91_RS22905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BUW91_RS22910	COG0157	Belongs to the NadC ModD family
BUW91_RS22915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BUW91_RS22925	COG1827	regulation of RNA biosynthetic process
BUW91_RS22930	COG0077	Prephenate dehydratase
BUW91_RS22935	COG4492	Belongs to the UPF0735 family
BUW91_RS22940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BUW91_RS22955	COG2868	ribosomal protein
BUW91_RS22965	COG1530	ribonuclease E activity
BUW91_RS22970	COG1994	Peptidase M50
BUW91_RS22975	COG0739	heme binding
BUW91_RS22980	COG2894	cell division
BUW91_RS22985	COG0850	regulation of cytokinetic process
BUW91_RS22990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BUW91_RS22995	COG1792	Involved in formation and maintenance of cell shape
BUW91_RS23000	COG1077	Cell shape determining protein MreB Mrl
BUW91_RS23005	COG2003	Belongs to the UPF0758 family
BUW91_RS23010	COG0424	maF-like protein
BUW91_RS23020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BUW91_RS23030	COG2322	membrane
BUW91_RS23035	COG0285	dihydrofolate synthase activity
BUW91_RS23040	COG0525	valine-tRNA ligase activity
BUW91_RS23050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUW91_RS23055	COG1388	LysM domain
BUW91_RS23065	COG0113	porphobilinogen synthase activity
BUW91_RS23070	COG1587	Uroporphyrinogen-III synthase
BUW91_RS23075	COG0181	hydroxymethylbilane synthase activity
BUW91_RS23080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BUW91_RS23095	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BUW91_RS23100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BUW91_RS23105	COG0470	DNA polymerase III
BUW91_RS23105	COG1067	ATP-dependent peptidase activity
BUW91_RS23110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BUW91_RS23115	COG0544	peptidyl-prolyl cis-trans isomerase activity
BUW91_RS23120	COG0457	Tetratricopeptide repeat
BUW91_RS23120	COG1477	protein flavinylation
BUW91_RS23125	COG0066	3-isopropylmalate dehydratase activity
BUW91_RS23130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BUW91_RS23140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BUW91_RS23145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BUW91_RS23150	COG0440	acetolactate synthase activity
BUW91_RS23155	COG0028	Belongs to the TPP enzyme family
BUW91_RS23165	COG0622	Phosphoesterase
BUW91_RS23180	COG5401	PFAM Sporulation and spore germination
BUW91_RS23185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BUW91_RS23190	COG1846	Transcriptional regulator
BUW91_RS23200	COG0306	phosphate transporter
BUW91_RS23205	COG1392	Phosphate transport regulator
BUW91_RS23210	COG0768	penicillin binding
BUW91_RS23220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BUW91_RS23225	COG0431	NADPH-dependent FMN reductase
BUW91_RS23230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_RS23235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_RS23240	COG1116	anion transmembrane transporter activity
BUW91_RS23245	COG0475	glutathione-regulated potassium exporter activity
BUW91_RS23250	COG0490	domain, Protein
BUW91_RS23260	COG2197	response regulator
BUW91_RS23265	COG0824	Thioesterase
BUW91_RS23270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BUW91_RS23275	COG1053	succinate dehydrogenase
BUW91_RS23280	COG2009	succinate dehydrogenase
BUW91_RS23285	COG1719	4-vinyl reductase, 4VR
BUW91_RS23290	COG0527	aspartate kinase activity
BUW91_RS23300	COG3118	belongs to the thioredoxin family
BUW91_RS23305	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BUW91_RS23310	COG2086	electron transfer activity
BUW91_RS23315	COG1024	Enoyl-CoA hydratase
BUW91_RS23320	COG1309	transcriptional regulator
BUW91_RS23325	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS23330	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BUW91_RS23335	COG3766	membrane
BUW91_RS23340	COG1193	negative regulation of DNA recombination
BUW91_RS23345	COG1796	DNA polymerase
BUW91_RS23345	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BUW91_RS23350	COG1286	toxin biosynthetic process
BUW91_RS23355	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BUW91_RS23360	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BUW91_RS23365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUW91_RS23365	COG0072	phenylalanine-tRNA ligase activity
BUW91_RS23370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BUW91_RS23375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BUW91_RS23405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BUW91_RS23410	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BUW91_RS23415	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BUW91_RS23420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BUW91_RS23430	COG1484	DNA-dependent DNA replication
BUW91_RS23435	COG3611	Membrane attachment protein
BUW91_RS23440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BUW91_RS23450	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BUW91_RS23455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BUW91_RS23460	COG0237	dephospho-CoA kinase activity
BUW91_RS23465	COG1971	Probably functions as a manganese efflux pump
BUW91_RS23470	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BUW91_RS23475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_RS23475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BUW91_RS23480	COG5002	protein histidine kinase activity
BUW91_RS23485	COG0745	RESPONSE REGULATOR receiver
BUW91_RS23495	COG0039	L-malate dehydrogenase activity
BUW91_RS23500	COG0538	isocitrate dehydrogenase activity
BUW91_RS23505	COG0372	Belongs to the citrate synthase family
BUW91_RS23510	COG2707	UPF0756 membrane protein
BUW91_RS23515	COG0628	permease
BUW91_RS23520	COG3030	protein affecting phage T7 exclusion by the F plasmid
BUW91_RS23530	COG0825	malonyl-CoA metabolic process
BUW91_RS23535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BUW91_RS23540	COG2186	Transcriptional regulator
BUW91_RS23545	COG0281	malic enzyme
BUW91_RS23550	COG0587	DNA-directed DNA polymerase activity
BUW91_RS23565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BUW91_RS23575	COG4109	DRTGG domain
BUW91_RS23595	COG0165	Argininosuccinate lyase
BUW91_RS23600	COG0137	argininosuccinate synthase activity
BUW91_RS23615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BUW91_RS23620	COG0827	DNA restriction-modification system
BUW91_RS23625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BUW91_RS23630	COG3874	Sporulation protein YtfJ
BUW91_RS23640	COG1714	RDD family
BUW91_RS23645	COG0616	signal peptide processing
BUW91_RS23650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BUW91_RS23655	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BUW91_RS23665	COG0301	tRNA thio-modification
BUW91_RS23670	COG1104	cysteine desulfurase activity
BUW91_RS23675	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BUW91_RS23685	COG1309	transcriptional regulator
BUW91_RS23690	COG1956	GAF domain-containing protein
BUW91_RS23705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BUW91_RS23710	COG0454	-acetyltransferase
BUW91_RS23715	COG0517	IMP dehydrogenase activity
BUW91_RS23720	COG0123	including yeast histone deacetylase and acetoin utilization protein
BUW91_RS23740	COG1605	Chorismate mutase
BUW91_RS23740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BUW91_RS23745	COG3118	belongs to the thioredoxin family
BUW91_RS23750	COG4980	gas vesicle protein
BUW91_RS23765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BUW91_RS23775	COG1674	ftsk spoiiie
BUW91_RS23780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BUW91_RS23785	COG4848	Belongs to the UPF0354 family
BUW91_RS23790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS23795	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BUW91_RS23800	COG1363	Peptidase, m42
BUW91_RS23805	COG5584	Small secreted protein
BUW91_RS23810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BUW91_RS23815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BUW91_RS23825	COG0510	thiamine kinase activity
BUW91_RS23840	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BUW91_RS23845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BUW91_RS23850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BUW91_RS23855	COG1349	DNA-binding transcription factor activity
BUW91_RS23860	COG1187	pseudouridine synthase activity
BUW91_RS23865	COG2244	polysaccharide biosynthetic process
BUW91_RS23870	COG2081	HI0933 family
BUW91_RS23880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BUW91_RS23885	COG0495	leucyl-tRNA aminoacylation
BUW91_RS23895	COG2610	gluconate transmembrane transporter activity
BUW91_RS23900	COG2814	Major facilitator Superfamily
BUW91_RS23915	COG1242	4 iron, 4 sulfur cluster binding
BUW91_RS23920	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BUW91_RS23930	COG2267	carboxylic ester hydrolase activity
BUW91_RS23935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BUW91_RS23940	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS23945	COG0438	transferase activity, transferring glycosyl groups
BUW91_RS23950	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BUW91_RS23955	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BUW91_RS23965	COG1506	peptidase
BUW91_RS23970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BUW91_RS23980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BUW91_RS23985	COG0494	nUDIX hydrolase
BUW91_RS23995	COG4824	toxin secretion phage lysis holin
BUW91_RS24000	COG0783	Belongs to the Dps family
BUW91_RS24010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BUW91_RS24015	COG0288	reversible hydration of carbon dioxide
BUW91_RS24020	COG0523	cobalamin synthesis protein
BUW91_RS24030	COG0254	rRNA binding
BUW91_RS24035	COG1271	oxidase subunit
BUW91_RS24040	COG1294	oxidase, subunit
BUW91_RS24045	COG0716	FMN binding
BUW91_RS24070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_RS24075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BUW91_RS24080	COG4948	Mandelate Racemase Muconate Lactonizing
BUW91_RS24090	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BUW91_RS24095	COG0596	Alpha beta hydrolase
BUW91_RS24100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BUW91_RS24105	COG1169	isochorismate synthase
BUW91_RS24110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BUW91_RS24120	COG0058	SHG alpha-glucan phosphorylase activity
BUW91_RS24125	COG0297	glycogen (starch) synthase activity
BUW91_RS24130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BUW91_RS24135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BUW91_RS24265	COG0318	PFAM AMP-dependent synthetase and ligase
BUW91_RS24270	COG1285	pathogenesis
BUW91_RS24290	COG0529	Catalyzes the synthesis of activated sulfate
BUW91_RS24300	COG0306	phosphate transporter
BUW91_RS24310	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUW91_RS24315	COG0346	lactoylglutathione lyase activity
BUW91_RS24320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BUW91_RS24330	COG0166	Belongs to the GPI family
BUW91_RS24340	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BUW91_RS24340	COG2111	Na H antiporter
BUW91_RS24345	COG2111	Na H antiporter
BUW91_RS24350	COG1006	Multisubunit Na H antiporter MnhC subunit
BUW91_RS24355	COG0651	ATP synthesis coupled electron transport
BUW91_RS24360	COG1863	multisubunit Na H antiporter MnhE subunit
BUW91_RS24365	COG2212	antiporter activity
BUW91_RS24370	COG1320	monovalent cation:proton antiporter activity
BUW91_RS24375	COG1979	alcohol dehydrogenase
BUW91_RS24380	COG2155	Conserved Protein
BUW91_RS24385	COG1098	S1 RNA binding domain
BUW91_RS24390	COG0436	Aminotransferase
BUW91_RS24395	COG1522	sequence-specific DNA binding
BUW91_RS24400	COG2267	carboxylic ester hydrolase activity
BUW91_RS24405	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BUW91_RS24410	COG2032	superoxide dismutase activity
BUW91_RS24425	COG5018	Exonuclease
BUW91_RS24430	COG2050	protein possibly involved in aromatic compounds catabolism
BUW91_RS24440	COG1418	mRNA catabolic process
BUW91_RS24450	COG2056	Na+-H+ antiporter family
BUW91_RS24455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BUW91_RS24460	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BUW91_RS24465	COG3584	3D domain protein
BUW91_RS24475	COG1252	NADH dehydrogenase
BUW91_RS24480	COG0492	ferredoxin-NADP+ reductase activity
BUW91_RS24490	COG0316	Belongs to the HesB IscA family
BUW91_RS24495	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BUW91_RS24505	COG4844	belongs to the
BUW91_RS24510	COG1252	NADH dehydrogenase
BUW91_RS24515	COG4837	Protein of unknown function (DUF1462)
BUW91_RS24520	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BUW91_RS24525	COG0083	homoserine kinase activity
BUW91_RS24530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BUW91_RS24535	COG0460	homoserine dehydrogenase
BUW91_RS24540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BUW91_RS24545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BUW91_RS24550	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BUW91_RS24555	COG0647	UMP catabolic process
BUW91_RS24560	COG2445	Protein of unknown function DUF86
BUW91_RS24570	COG4470	Protein conserved in bacteria
BUW91_RS24580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BUW91_RS24585	COG0739	heme binding
BUW91_RS24590	COG0733	neurotransmitter:sodium symporter activity
BUW91_RS24600	COG3377	Domain of unknown function (DUF1805)
BUW91_RS24605	COG1801	Protein of unknown function DUF72
BUW91_RS24610	COG0719	Fe-S assembly protein
BUW91_RS24615	COG0822	iron-sulfur transferase activity
BUW91_RS24620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BUW91_RS24625	COG0719	Fe-S assembly protein
BUW91_RS24630	COG0396	ATPase activity
BUW91_RS24635	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUW91_RS24640	COG1464	Belongs to the NlpA lipoprotein family
BUW91_RS24645	COG2011	ABC-type metal ion transport system permease component
BUW91_RS24650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BUW91_RS24655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BUW91_RS24660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BUW91_RS24670	COG0509	glycine decarboxylation via glycine cleavage system
BUW91_RS24675	COG1393	Belongs to the ArsC family
BUW91_RS24680	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS24685	COG0183	Belongs to the thiolase family
BUW91_RS24690	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_RS24690	COG1024	Enoyl-CoA hydratase
BUW91_RS24715	COG1120	ATPase activity
BUW91_RS24720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS24725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BUW91_RS24730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BUW91_RS24740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BUW91_RS24745	COG1309	transcriptional regulator
BUW91_RS24755	COG1028	Short-chain dehydrogenase reductase Sdr
BUW91_RS24760	COG0477	Major facilitator Superfamily
BUW91_RS24765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BUW91_RS24770	COG0583	DNA-binding transcription factor activity
BUW91_RS24780	COG0672	)-iron permease
BUW91_RS24785	COG5002	protein histidine kinase activity
BUW91_RS24785	COG3850	Histidine kinase
BUW91_RS24790	COG0745	RESPONSE REGULATOR receiver
BUW91_RS24795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BUW91_RS24800	COG0671	phosphoesterase, PA-phosphatase related
BUW91_RS24810	COG1846	Transcriptional regulator
BUW91_RS24815	COG0778	Nitroreductase
BUW91_RS24820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BUW91_RS24825	COG0314	molybdopterin synthase activity
BUW91_RS24830	COG1763	Mo-molybdopterin cofactor biosynthetic process
BUW91_RS24835	COG0303	'Molybdopterin
BUW91_RS24845	COG0746	molybdenum cofactor guanylyltransferase activity
BUW91_RS24855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BUW91_RS24860	COG5609	conserved protein (DUF2294)
BUW91_RS24865	COG3383	formate dehydrogenase (NAD+) activity
BUW91_RS24870	COG2427	Protein of unknown function (DUF1641)
BUW91_RS24875	COG0725	ABC transporter, periplasmic molybdate-binding protein
BUW91_RS24880	COG4149	molybdate abc transporter
BUW91_RS24890	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BUW91_RS24895	COG0557	exoribonuclease II activity
BUW91_RS24900	COG1647	Serine aminopeptidase, S33
BUW91_RS24905	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BUW91_RS24915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BUW91_RS24945	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BUW91_RS24965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BUW91_RS24975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BUW91_RS24980	COG1660	Displays ATPase and GTPase activities
BUW91_RS24985	COG1051	belongs to the nudix hydrolase family
BUW91_RS24990	COG0492	ferredoxin-NADP+ reductase activity
BUW91_RS24995	COG0457	Tetratricopeptide repeat
BUW91_RS25000	COG0140	phosphoribosyl-ATP diphosphatase activity
BUW91_RS25000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BUW91_RS25005	COG0107	imidazoleglycerol-phosphate synthase activity
BUW91_RS25010	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BUW91_RS25015	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BUW91_RS25020	COG0131	Imidazoleglycerol-phosphate dehydratase
BUW91_RS25025	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BUW91_RS25030	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BUW91_RS25040	COG0110	maltose O-acetyltransferase activity
BUW91_RS25045	COG0546	phosphoglycolate phosphatase activity
BUW91_RS25050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BUW91_RS25055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BUW91_RS25060	COG1950	PFAM Membrane protein of
BUW91_RS25065	COG1983	PspC domain protein
BUW91_RS25070	COG3595	metallopeptidase activity
BUW91_RS25080	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BUW91_RS25085	COG0556	nucleotide-excision repair
BUW91_RS25090	COG2204	response regulator
BUW91_RS25095	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS25100	COG0506	proline dehydrogenase activity
BUW91_RS25105	COG4897	Protein conserved in bacteria
BUW91_RS25110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BUW91_RS25115	COG3409	Peptidoglycan-binding domain 1 protein
BUW91_RS25115	COG0793	Belongs to the peptidase S41A family
BUW91_RS25120	COG0739	heme binding
BUW91_RS25125	COG2177	Part of the ABC transporter FtsEX involved in
BUW91_RS25130	COG2884	Cell division ATP-binding protein ftsE
BUW91_RS25135	COG0655	NAD(P)H dehydrogenase (quinone) activity
BUW91_RS25145	COG0805	protein transport
BUW91_RS25150	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BUW91_RS25160	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BUW91_RS25165	COG0653	protein targeting
BUW91_RS25175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BUW91_RS25185	COG1516	flagellar protein fliS
BUW91_RS25190	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BUW91_RS25200	COG1113	amino acid transport
BUW91_RS25210	COG1012	belongs to the aldehyde dehydrogenase family
BUW91_RS25215	COG1454	alcohol dehydrogenase
BUW91_RS25220	COG1510	regulation of RNA biosynthetic process
BUW91_RS25225	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BUW91_RS25230	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BUW91_RS25235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BUW91_RS25240	COG4786	Flagellar basal body rod
BUW91_RS25240	COG1256	bacterial-type flagellum assembly
BUW91_RS25260	COG1040	competence protein
BUW91_RS25265	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BUW91_RS25270	COG1307	EDD domain protein, DegV family
BUW91_RS25275	COG1728	Protein conserved in bacteria
BUW91_RS25285	COG2197	response regulator
BUW91_RS25290	COG4585	Histidine kinase
BUW91_RS25295	COG1739	Uncharacterized protein family UPF0029
BUW91_RS25300	COG1316	TRANSCRIPTIONal
BUW91_RS25305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BUW91_RS25310	COG1585	Membrane protein implicated in regulation of membrane protease activity
BUW91_RS25315	COG2268	Band 7 protein
BUW91_RS25320	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BUW91_RS25330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BUW91_RS25340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BUW91_RS25345	COG0791	NLP P60 protein
BUW91_RS25345	COG1388	LysM domain
BUW91_RS25350	COG0629	single-stranded DNA binding
BUW91_RS25375	COG4786	Flagellar basal body rod
BUW91_RS25380	COG4786	Flagellar basal body rod
BUW91_RS25385	COG1077	Cell shape determining protein MreB Mrl
BUW91_RS25390	COG1609	Transcriptional regulator
BUW91_RS25395	COG0739	heme binding
BUW91_RS25400	COG2385	sporulation resulting in formation of a cellular spore
BUW91_RS25415	COG4836	Membrane
BUW91_RS25420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BUW91_RS25425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BUW91_RS25430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BUW91_RS25435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BUW91_RS25440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUW91_RS25445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BUW91_RS25450	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BUW91_RS25455	COG0356	it plays a direct role in the translocation of protons across the membrane
BUW91_RS25470	COG1404	Belongs to the peptidase S8 family
BUW91_RS25475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BUW91_RS25480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BUW91_RS25495	COG0698	ribose 5-phosphate isomerase
BUW91_RS25505	COG1971	Probably functions as a manganese efflux pump
BUW91_RS25510	COG0009	L-threonylcarbamoyladenylate synthase
BUW91_RS25530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BUW91_RS25545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BUW91_RS25555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BUW91_RS25560	COG0191	fructose-bisphosphate aldolase activity
BUW91_RS25565	COG2204	response regulator
BUW91_RS25570	COG4821	SIS domain
BUW91_RS25575	COG0504	CTP synthase activity
BUW91_RS25585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS25585	COG1703	isobutyryl-CoA mutase activity
BUW91_RS25585	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BUW91_RS25595	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS25600	COG1960	acyl-CoA dehydrogenase activity
BUW91_RS25605	COG1250	3-hydroxyacyl-CoA dehydrogenase
BUW91_RS25610	COG0183	Belongs to the thiolase family
BUW91_RS25615	COG2181	nitrate reductase activity
BUW91_RS25615	COG0247	lactate metabolic process
BUW91_RS25620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BUW91_RS25625	COG4294	response to UV
BUW91_RS25630	COG0018	arginyl-trna synthetase
BUW91_RS25635	COG4506	Protein conserved in bacteria
BUW91_RS25640	COG0010	Belongs to the arginase family
BUW91_RS25645	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BUW91_RS25650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BUW91_RS25660	COG1994	Peptidase M50
BUW91_RS25665	COG1942	4-Oxalocrotonate Tautomerase
BUW91_RS25670	COG3465	dGTPase activity
BUW91_RS25680	COG4844	belongs to the
BUW91_RS25690	COG0095	Lipoate-protein ligase
BUW91_RS25695	COG0280	phosphate acetyltransferase
BUW91_RS25700	COG3253	May function as heme-dependent peroxidase
BUW91_RS25705	COG3773	Cell wall hydrolase
BUW91_RS25715	COG2363	Small membrane protein
BUW91_RS25725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BUW91_RS25740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BUW91_RS25745	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BUW91_RS25745	COG2508	Transcriptional regulator
BUW91_RS25750	COG0686	Belongs to the AlaDH PNT family
BUW91_RS25760	COG0351	phosphomethylpyrimidine kinase
BUW91_RS25765	COG0561	phosphatase activity
BUW91_RS25770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BUW91_RS25775	COG1263	PTS System
BUW91_RS25775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BUW91_RS25775	COG2190	(PTS) system
BUW91_RS25785	COG0438	transferase activity, transferring glycosyl groups
BUW91_RS25800	COG2076	Multidrug Resistance protein
BUW91_RS25810	COG0728	peptidoglycan biosynthetic process
BUW91_RS25825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BUW91_RS25830	COG4988	ABC transporter
BUW91_RS25835	COG1294	oxidase, subunit
BUW91_RS25840	COG1271	oxidase subunit
BUW91_RS25845	COG3610	response to peptide
BUW91_RS25850	COG2966	Psort location CytoplasmicMembrane, score
BUW91_RS25855	COG1609	Transcriptional regulator
BUW91_RS25865	COG2814	Major facilitator Superfamily
BUW91_RS25880	COG1966	Carbon starvation protein
BUW91_RS25885	COG0753	catalase activity
BUW91_RS25900	COG0471	metal ion transport
BUW91_RS25905	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BUW91_RS25915	COG0745	RESPONSE REGULATOR receiver
BUW91_RS25935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BUW91_RS25940	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BUW91_RS25955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BUW91_RS25960	COG4853	Protein conserved in bacteria
BUW91_RS25970	COG5002	protein histidine kinase activity
BUW91_RS25975	COG0745	RESPONSE REGULATOR receiver
BUW91_RS26000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BUW91_RS26005	COG0305	Participates in initiation and elongation during chromosome replication
BUW91_RS26015	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BUW91_RS26025	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BUW91_RS26035	COG0360	Binds together with S18 to 16S ribosomal RNA
BUW91_RS26040	COG0012	GTP binding
BUW91_RS26045	COG4481	Protein conserved in bacteria
BUW91_RS26050	COG0668	transmembrane transport
BUW91_RS26065	COG1475	DNA binding
BUW91_RS26070	COG1192	Involved in chromosome partitioning
BUW91_RS26075	COG1475	DNA binding
BUW91_RS26085	COG0445	tRNA wobble uridine modification
BUW91_RS26090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BUW91_RS26095	COG1847	R3H domain protein
BUW91_RS26100	COG0706	membrane insertase activity
BUW91_RS26105	COG0594	ribonuclease P activity
BUW91_RS26110	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BUW91_RS26420	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BUW91_RS26545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BUW91_RS26865	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BUW91_RS27180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUW91_RS27270	COG0037	tRNA processing
BUW91_RS27300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BUW91_RS27515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BUW91_RS27535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BUW91_RS27585	COG0187	DNA topoisomerase II activity
BUW91_RS27600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS27685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BUW91_RS27745	COG1982	Orn Lys Arg decarboxylase major
BUW91_RS27850	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BUW91_RS27860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUW91_RS27870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BUW91_RS28155	COG0187	DNA topoisomerase II activity
BUW91_RS28160	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS28165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS28235	COG0516	GMP reductase activity
BUW91_RS28235	COG0517	IMP dehydrogenase activity
BUW91_RS28240	COG0517	IMP dehydrogenase activity
BUW91_RS28240	COG0516	GMP reductase activity
BUW91_RS28570	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BUW91_RS28625	COG1686	Belongs to the peptidase S11 family
BUW91_RS28640	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BUW91_RS28775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BUW91_RS28795	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner