locus-tag	class	description
G5C61_RS00010	COG2153	protein acetylation
G5C61_RS00015	COG0129	dihydroxy-acid dehydratase activity
G5C61_RS00020	COG2267	carboxylic ester hydrolase activity
G5C61_RS00025	COG1227	inorganic diphosphatase activity
G5C61_RS00040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G5C61_RS00050	COG0204	Acyl-transferase
G5C61_RS00055	COG2233	PERMEase
G5C61_RS00070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS00085	COG1914	H( )-stimulated, divalent metal cation uptake system
G5C61_RS00100	COG1011	Hydrolase
G5C61_RS00105	COG1846	Transcriptional regulator
G5C61_RS00115	COG4974	Belongs to the 'phage' integrase family
G5C61_RS00130	COG0531	amino acid
G5C61_RS00135	COG4302	ethanolamine ammonia-lyase activity
G5C61_RS00140	COG4303	Ethanolamine ammonia lyase large subunit
G5C61_RS00145	COG4819	ethanolamine utilization protein
G5C61_RS00155	COG0833	amino acid
G5C61_RS00165	COG1247	-acetyltransferase
G5C61_RS00170	COG1335	isochorismatase
G5C61_RS00180	COG3403	YqcI/YcgG family
G5C61_RS00185	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS00190	COG2267	carboxylic ester hydrolase activity
G5C61_RS00195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G5C61_RS00200	COG0187	DNA topoisomerase II activity
G5C61_RS00205	COG1832	CoA-binding protein
G5C61_RS00210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G5C61_RS00215	COG4841	protein insertion into membrane
G5C61_RS00220	COG0824	Thioesterase
G5C61_RS00250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS00255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G5C61_RS00275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
G5C61_RS00310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G5C61_RS00315	COG2068	MobA-Related Protein
G5C61_RS00320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G5C61_RS00375	COG1183	phosphatidylcholine synthase activity
G5C61_RS00390	COG2814	Major facilitator Superfamily
G5C61_RS00395	COG1683	Conserved Protein
G5C61_RS00410	COG1295	ribonuclease BN
G5C61_RS00430	COG2814	Major facilitator Superfamily
G5C61_RS00440	COG2814	Major facilitator Superfamily
G5C61_RS00445	COG0789	Transcriptional regulator
G5C61_RS00455	COG0288	reversible hydration of carbon dioxide
G5C61_RS00460	COG0659	secondary active sulfate transmembrane transporter activity
G5C61_RS00465	COG0745	RESPONSE REGULATOR receiver
G5C61_RS00470	COG5002	protein histidine kinase activity
G5C61_RS00485	COG4282	regulation of fungal-type cell wall biogenesis
G5C61_RS00490	COG0531	amino acid
G5C61_RS00500	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS00505	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
G5C61_RS00580	COG1363	Peptidase, m42
G5C61_RS00590	COG1114	Component of the transport system for branched-chain amino acids
G5C61_RS00610	COG0004	ammonium transporteR
G5C61_RS00625	COG1252	NADH dehydrogenase
G5C61_RS00630	COG0679	Auxin Efflux Carrier
G5C61_RS00635	COG0281	malic enzyme
G5C61_RS00660	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G5C61_RS00665	COG0163	prenyltransferase activity
G5C61_RS00670	COG0583	DNA-binding transcription factor activity
G5C61_RS00675	COG0679	Auxin Efflux Carrier
G5C61_RS00695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS00700	COG0247	lactate metabolic process
G5C61_RS00705	COG0277	FAD linked oxidase domain protein
G5C61_RS00710	COG3835	regulator
G5C61_RS00715	COG0693	protein deglycase activity
G5C61_RS00730	COG2610	gluconate transmembrane transporter activity
G5C61_RS00750	COG1131	(ABC) transporter
G5C61_RS00760	COG2197	response regulator
G5C61_RS00795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS00805	COG0586	Pfam SNARE associated Golgi protein
G5C61_RS00810	COG1515	deoxyribonuclease V activity
G5C61_RS00815	COG0584	glycerophosphoryl diester phosphodiesterase
G5C61_RS00820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5C61_RS00830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5C61_RS00835	COG0531	amino acid
G5C61_RS00940	COG5444	nuclease activity
G5C61_RS00955	COG0534	Mate efflux family protein
G5C61_RS00960	COG1566	PFAM secretion protein HlyD family protein
G5C61_RS00970	COG1846	Transcriptional regulator
G5C61_RS00975	COG0708	Exodeoxyribonuclease III
G5C61_RS00995	COG0673	inositol 2-dehydrogenase activity
G5C61_RS01000	COG1349	DNA-binding transcription factor activity
G5C61_RS01005	COG3853	Toxic anion resistance protein (TelA)
G5C61_RS01015	COG2310	stress, protein
G5C61_RS01020	COG2310	stress, protein
G5C61_RS01025	COG2310	stress, protein
G5C61_RS01030	COG0737	Belongs to the 5'-nucleotidase family
G5C61_RS01045	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G5C61_RS01050	COG1131	(ABC) transporter
G5C61_RS01060	COG2084	Dehydrogenase
G5C61_RS01065	COG1278	Cold shock
G5C61_RS01070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS01075	COG0028	Belongs to the TPP enzyme family
G5C61_RS01080	COG1278	Cold shock
G5C61_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS01120	COG0427	acetyl-CoA hydrolase
G5C61_RS01125	COG3279	Response regulator of the LytR AlgR family
G5C61_RS01130	COG2323	membrane
G5C61_RS01135	COG2814	Major facilitator Superfamily
G5C61_RS01140	COG1388	LysM domain
G5C61_RS01140	COG3584	3D domain protein
G5C61_RS01145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G5C61_RS01175	COG3340	Belongs to the peptidase S51 family
G5C61_RS01230	COG0579	oxidoreductase
G5C61_RS01245	COG5444	nuclease activity
G5C61_RS01270	COG1486	melibiose metabolic process
G5C61_RS01275	COG0395	ABC-type sugar transport system, permease component
G5C61_RS01280	COG1175	transmembrane transport
G5C61_RS01285	COG1653	transport
G5C61_RS01290	COG1609	Transcriptional regulator
G5C61_RS01325	COG1929	Belongs to the glycerate kinase type-1 family
G5C61_RS01330	COG2610	gluconate transmembrane transporter activity
G5C61_RS01335	COG3835	regulator
G5C61_RS01340	COG3290	protein histidine kinase activity
G5C61_RS01340	COG3829	transcription factor binding
G5C61_RS01350	COG1454	alcohol dehydrogenase
G5C61_RS01355	COG3152	Membrane
G5C61_RS01375	COG0531	amino acid
G5C61_RS01380	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G5C61_RS01385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5C61_RS01400	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G5C61_RS01430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G5C61_RS01430	COG0456	acetyltransferase
G5C61_RS01470	COG2801	Transposase and inactivated derivatives
G5C61_RS01500	COG0393	Putative heavy-metal-binding
G5C61_RS01540	COG5577	PFAM Coat F domain
G5C61_RS01555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS01560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS01565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS01575	COG0697	spore germination
G5C61_RS01585	COG1811	Na channel or pump
G5C61_RS01590	COG4978	Transcriptional regulator
G5C61_RS01590	COG0789	Transcriptional regulator
G5C61_RS01595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5C61_RS01600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G5C61_RS01625	COG1469	GTP cyclohydrolase I activity
G5C61_RS01635	COG0113	porphobilinogen synthase activity
G5C61_RS01645	COG0735	belongs to the Fur family
G5C61_RS01665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G5C61_RS01665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G5C61_RS01680	COG0523	cobalamin synthesis protein
G5C61_RS01685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5C61_RS01690	COG1121	(ABC) transporter
G5C61_RS01695	COG0803	Belongs to the bacterial solute-binding protein 9 family
G5C61_RS01700	COG0701	Predicted permease
G5C61_RS01710	COG0523	cobalamin synthesis protein
G5C61_RS01720	COG1124	(ABC) transporter
G5C61_RS01725	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS01730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS01735	COG0601	transmembrane transport
G5C61_RS01740	COG0747	negative chemotaxis
G5C61_RS01760	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS01765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS01770	COG0697	spore germination
G5C61_RS01805	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS01810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS01815	COG0601	transmembrane transport
G5C61_RS01820	COG0747	negative chemotaxis
G5C61_RS01825	COG4166	transmembrane transport
G5C61_RS01840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS01845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS01850	COG3152	Membrane
G5C61_RS01855	COG3152	Membrane
G5C61_RS01875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G5C61_RS01885	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G5C61_RS01900	COG2390	Transcriptional regulator
G5C61_RS01930	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G5C61_RS01935	COG0501	Belongs to the peptidase M48B family
G5C61_RS01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS01945	COG1742	UPF0060 membrane protein
G5C61_RS01955	COG2182	Extracellular solute-binding protein
G5C61_RS01975	COG2031	fatty acid transporter
G5C61_RS02000	COG2391	methyltransferase activity
G5C61_RS02015	COG1979	alcohol dehydrogenase
G5C61_RS02020	COG0583	DNA-binding transcription factor activity
G5C61_RS02035	COG0456	acetyltransferase
G5C61_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS02075	COG1063	alcohol dehydrogenase
G5C61_RS02100	COG0025	NhaP-type Na H and K H
G5C61_RS02105	COG1253	flavin adenine dinucleotide binding
G5C61_RS02130	COG4608	Belongs to the ABC transporter superfamily
G5C61_RS02140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS02145	COG0601	transmembrane transport
G5C61_RS02150	COG0747	negative chemotaxis
G5C61_RS02160	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS02175	COG1525	nuclease
G5C61_RS02185	COG0579	oxidoreductase
G5C61_RS02190	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G5C61_RS02195	COG0561	phosphatase activity
G5C61_RS02210	COG0668	transmembrane transport
G5C61_RS02250	COG2309	aminopeptidase activity
G5C61_RS02255	COG1414	Transcriptional regulator
G5C61_RS02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5C61_RS02265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G5C61_RS02270	COG0277	FAD linked oxidase domain protein
G5C61_RS02275	COG0247	lactate metabolic process
G5C61_RS02280	COG0277	FAD linked oxidase domain protein
G5C61_RS02285	COG1620	l-lactate permease
G5C61_RS02305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G5C61_RS02310	COG1131	(ABC) transporter
G5C61_RS02330	COG1595	DNA-templated transcription, initiation
G5C61_RS02355	COG4682	membrane
G5C61_RS02370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS02375	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS02380	COG0598	Magnesium transport protein CorA
G5C61_RS02385	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G5C61_RS02395	COG2323	membrane
G5C61_RS02400	COG1876	peptidase activity
G5C61_RS02410	COG5002	protein histidine kinase activity
G5C61_RS02415	COG0745	RESPONSE REGULATOR receiver
G5C61_RS02435	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5C61_RS02440	COG0567	Dehydrogenase, E1 component
G5C61_RS02450	COG2814	Major facilitator Superfamily
G5C61_RS02455	COG1764	response to oxidative stress
G5C61_RS02465	COG2311	Membrane
G5C61_RS02505	COG0347	Belongs to the P(II) protein family
G5C61_RS02510	COG0004	ammonium transporteR
G5C61_RS02515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
G5C61_RS02535	COG0596	Alpha beta hydrolase
G5C61_RS02550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G5C61_RS02550	COG0456	acetyltransferase
G5C61_RS02555	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS02595	COG4604	ABC transporter, ATP-binding protein
G5C61_RS02600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS02605	COG1492	cobalamin metabolic process
G5C61_RS02615	COG0531	amino acid
G5C61_RS02625	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS02630	COG2404	hydrolase activity, acting on ester bonds
G5C61_RS02635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G5C61_RS02645	COG1609	Transcriptional regulator
G5C61_RS02655	COG2271	Major facilitator Superfamily
G5C61_RS02660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS02675	COG1233	COG1233 Phytoene dehydrogenase and related
G5C61_RS02680	COG1215	transferase activity, transferring glycosyl groups
G5C61_RS02735	COG0831	urea catabolic process
G5C61_RS02740	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G5C61_RS02745	COG0791	NLP P60 protein
G5C61_RS02745	COG1388	LysM domain
G5C61_RS02750	COG1388	LysM domain
G5C61_RS02750	COG3584	3D domain protein
G5C61_RS02755	COG0778	Nitroreductase
G5C61_RS02760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G5C61_RS02765	COG0586	Pfam SNARE associated Golgi protein
G5C61_RS02775	COG0400	carboxylic ester hydrolase activity
G5C61_RS02780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5C61_RS02785	COG2244	polysaccharide biosynthetic process
G5C61_RS02790	COG0697	spore germination
G5C61_RS02795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS02815	COG1132	(ABC) transporter
G5C61_RS02840	COG4195	phage-related replication protein
G5C61_RS02855	COG0783	Belongs to the Dps family
G5C61_RS02865	COG5577	PFAM Coat F domain
G5C61_RS02870	COG1253	flavin adenine dinucleotide binding
G5C61_RS02885	COG0516	GMP reductase activity
G5C61_RS02885	COG0517	IMP dehydrogenase activity
G5C61_RS02900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5C61_RS02900	COG0723	plastoquinol--plastocyanin reductase activity
G5C61_RS02915	COG0287	Prephenate dehydrogenase
G5C61_RS02925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G5C61_RS02925	COG1605	Chorismate mutase
G5C61_RS02935	COG2059	Chromate
G5C61_RS02940	COG2059	Chromate
G5C61_RS02950	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G5C61_RS02955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5C61_RS02960	COG2508	Transcriptional regulator
G5C61_RS02965	COG0011	TIGRFAM Protein of
G5C61_RS02970	COG0791	NLP P60 protein
G5C61_RS02970	COG1388	LysM domain
G5C61_RS02985	COG0733	neurotransmitter:sodium symporter activity
G5C61_RS03030	COG0730	response to heat
G5C61_RS03035	COG1902	pentaerythritol trinitrate reductase activity
G5C61_RS03050	COG2205	protein histidine kinase activity
G5C61_RS03060	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G5C61_RS03095	COG0640	Transcriptional regulator
G5C61_RS03105	COG0778	Nitroreductase
G5C61_RS03120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G5C61_RS03125	COG3103	Sh3 type 3 domain protein
G5C61_RS03125	COG4991	sh3 domain protein
G5C61_RS03125	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS03130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G5C61_RS03135	COG2002	toxin-antitoxin pair type II binding
G5C61_RS03145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G5C61_RS03160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G5C61_RS03165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS03180	COG2211	Major facilitator Superfamily
G5C61_RS03185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS03190	COG1597	lipid kinase activity
G5C61_RS03200	COG0372	Belongs to the citrate synthase family
G5C61_RS03205	COG0583	DNA-binding transcription factor activity
G5C61_RS03210	COG0697	spore germination
G5C61_RS03215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS03240	COG2202	Pas domain
G5C61_RS03240	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS03245	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS03275	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS03280	COG2261	transglycosylase associated protein
G5C61_RS03295	COG0740	serine-type endopeptidase activity
G5C61_RS03310	COG1027	Aspartate ammonia-lyase
G5C61_RS03315	COG0252	asparaginase activity
G5C61_RS03320	COG1396	sequence-specific DNA binding
G5C61_RS03340	COG0640	Transcriptional regulator
G5C61_RS03360	COG0531	amino acid
G5C61_RS03365	COG1959	2 iron, 2 sulfur cluster binding
G5C61_RS03385	COG0281	malic enzyme
G5C61_RS03390	COG2746	aminoglycoside 3-N-acetyltransferase activity
G5C61_RS03400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS03405	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS03410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5C61_RS03415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G5C61_RS03430	COG0477	Major facilitator Superfamily
G5C61_RS03435	COG1846	Transcriptional regulator
G5C61_RS03440	COG0789	Transcriptional regulator
G5C61_RS03445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS03480	COG1819	glycosyl
G5C61_RS03495	COG1902	pentaerythritol trinitrate reductase activity
G5C61_RS03505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5C61_RS03520	COG2814	Major facilitator Superfamily
G5C61_RS03530	COG1228	amidohydrolase
G5C61_RS03540	COG1316	TRANSCRIPTIONal
G5C61_RS03545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS03565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G5C61_RS03575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G5C61_RS03640	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS03645	COG0531	amino acid
G5C61_RS03665	COG3764	Sortase (surface protein transpeptidase)
G5C61_RS03670	COG0730	response to heat
G5C61_RS03675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS03690	COG2130	NADP-dependent
G5C61_RS03710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS03725	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G5C61_RS03735	COG0501	Belongs to the peptidase M48B family
G5C61_RS03775	COG0131	Imidazoleglycerol-phosphate dehydratase
G5C61_RS03775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G5C61_RS03785	COG1309	transcriptional regulator
G5C61_RS03790	COG2076	Multidrug Resistance protein
G5C61_RS03795	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G5C61_RS03800	COG1278	Cold shock
G5C61_RS03805	COG2323	membrane
G5C61_RS03820	COG2910	NAD(P)H-binding
G5C61_RS03850	COG3546	catalase activity
G5C61_RS03855	COG4607	ABC-type enterochelin transport system periplasmic component
G5C61_RS03860	COG4604	ABC transporter, ATP-binding protein
G5C61_RS03865	COG4605	iron ion homeostasis
G5C61_RS03870	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS03875	COG3773	Cell wall hydrolase
G5C61_RS03905	COG1063	alcohol dehydrogenase
G5C61_RS03910	COG3775	system Galactitol-specific IIC component
G5C61_RS03915	COG3414	Phosphotransferase system galactitol-specific IIB component
G5C61_RS03930	COG2249	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS03935	COG0681	Belongs to the peptidase S26 family
G5C61_RS03955	COG1193	negative regulation of DNA recombination
G5C61_RS03965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G5C61_RS03970	COG1396	sequence-specific DNA binding
G5C61_RS03975	COG0861	Integral membrane protein TerC family
G5C61_RS03980	COG1609	Transcriptional regulator
G5C61_RS03985	COG1959	2 iron, 2 sulfur cluster binding
G5C61_RS04040	COG3773	Cell wall hydrolase
G5C61_RS04045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G5C61_RS04070	COG3546	catalase activity
G5C61_RS04090	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS04095	COG2207	Transcriptional regulator
G5C61_RS04095	COG1917	Cupin 2, conserved barrel domain protein
G5C61_RS04100	COG4585	Histidine kinase
G5C61_RS04120	COG3209	COG3209 Rhs family protein
G5C61_RS04145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G5C61_RS04155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5C61_RS04165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS04170	COG0346	lactoylglutathione lyase activity
G5C61_RS04185	COG1136	(ABC) transporter
G5C61_RS04190	COG0577	efflux transmembrane transporter activity
G5C61_RS04195	COG5002	protein histidine kinase activity
G5C61_RS04195	COG3850	Histidine kinase
G5C61_RS04220	COG5002	protein histidine kinase activity
G5C61_RS04225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS04250	COG4989	oxidoreductase activity
G5C61_RS04260	COG0697	spore germination
G5C61_RS04265	COG1917	Cupin 2, conserved barrel domain protein
G5C61_RS04265	COG2207	Transcriptional regulator
G5C61_RS04340	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
G5C61_RS04350	COG0583	DNA-binding transcription factor activity
G5C61_RS04360	COG1301	dicarboxylic acid transport
G5C61_RS04365	COG2824	Alkylphosphonate utilization operon protein PhnA
G5C61_RS04395	COG0405	Gamma-glutamyltransferase
G5C61_RS04400	COG1073	alpha beta
G5C61_RS04415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5C61_RS04420	COG4521	taurine ABC transporter
G5C61_RS04425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G5C61_RS04430	COG2175	clavaminate synthase activity
G5C61_RS04435	COG2814	Major facilitator Superfamily
G5C61_RS04455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS04465	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS04475	COG0745	RESPONSE REGULATOR receiver
G5C61_RS04480	COG0642	Histidine kinase
G5C61_RS04485	COG1136	(ABC) transporter
G5C61_RS04490	COG0577	efflux transmembrane transporter activity
G5C61_RS04500	COG0412	Dienelactone hydrolase
G5C61_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS04515	COG0730	response to heat
G5C61_RS04520	COG0425	Belongs to the sulfur carrier protein TusA family
G5C61_RS04525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5C61_RS04525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS04530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5C61_RS04530	COG0425	Belongs to the sulfur carrier protein TusA family
G5C61_RS04545	COG2210	Belongs to the sulfur carrier protein TusA family
G5C61_RS04550	COG0425	Belongs to the sulfur carrier protein TusA family
G5C61_RS04555	COG1937	Protein conserved in bacteria
G5C61_RS04575	COG0583	DNA-binding transcription factor activity
G5C61_RS04595	COG2188	Transcriptional regulator
G5C61_RS04605	COG2723	6-phospho-beta-galactosidase activity
G5C61_RS04635	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS04650	COG0583	DNA-binding transcription factor activity
G5C61_RS04655	COG0346	lactoylglutathione lyase activity
G5C61_RS04670	COG3706	GGDEF domain
G5C61_RS04675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G5C61_RS04695	COG0778	Nitroreductase
G5C61_RS04700	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS04720	COG1704	LemA family
G5C61_RS04730	COG1733	regulation of RNA biosynthetic process
G5C61_RS04735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G5C61_RS04740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G5C61_RS04745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS04770	COG0346	lactoylglutathione lyase activity
G5C61_RS04775	COG2808	Putative FMN-binding domain
G5C61_RS04795	COG0596	Alpha beta hydrolase
G5C61_RS04810	COG4807	Protein conserved in bacteria
G5C61_RS04820	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
G5C61_RS04825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS04830	COG1278	Cold shock
G5C61_RS04840	COG1278	Cold shock
G5C61_RS04850	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G5C61_RS04860	COG0477	Major facilitator Superfamily
G5C61_RS04900	COG0659	secondary active sulfate transmembrane transporter activity
G5C61_RS04910	COG2211	Major facilitator Superfamily
G5C61_RS04915	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
G5C61_RS04920	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
G5C61_RS04925	COG1691	(AIR) carboxylase
G5C61_RS04930	COG1606	tRNA processing
G5C61_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS04945	COG1904	glucuronate isomerase
G5C61_RS04980	COG2329	Antibiotic biosynthesis monooxygenase
G5C61_RS05000	COG0745	RESPONSE REGULATOR receiver
G5C61_RS05015	COG1131	(ABC) transporter
G5C61_RS05030	COG3655	Transcriptional regulator
G5C61_RS05040	COG0583	DNA-binding transcription factor activity
G5C61_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS05060	COG1609	Transcriptional regulator
G5C61_RS05065	COG1082	Xylose isomerase domain protein TIM barrel
G5C61_RS05070	COG0673	inositol 2-dehydrogenase activity
G5C61_RS05090	COG3718	enzyme involved in inositol metabolism
G5C61_RS05095	COG3962	Belongs to the TPP enzyme family
G5C61_RS05105	COG1349	DNA-binding transcription factor activity
G5C61_RS05115	COG0191	fructose-bisphosphate aldolase activity
G5C61_RS05120	COG1082	Xylose isomerase domain protein TIM barrel
G5C61_RS05125	COG2814	Major facilitator Superfamily
G5C61_RS05140	COG1064	alcohol dehydrogenase
G5C61_RS05145	COG0789	Transcriptional regulator
G5C61_RS05160	COG0662	Cupin 2, conserved barrel domain protein
G5C61_RS05180	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS05185	COG1278	Cold shock
G5C61_RS05190	COG3290	protein histidine kinase activity
G5C61_RS05190	COG0840	transmembrane signaling receptor activity
G5C61_RS05195	COG1876	peptidase activity
G5C61_RS05215	COG0598	Magnesium transport protein CorA
G5C61_RS05220	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS05245	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS05260	COG4335	DNA alkylation repair
G5C61_RS05265	COG0454	-acetyltransferase
G5C61_RS05315	COG3619	membrane
G5C61_RS05325	COG1349	DNA-binding transcription factor activity
G5C61_RS05330	COG0561	phosphatase activity
G5C61_RS05340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5C61_RS05355	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS05390	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5C61_RS05405	COG2160	L-arabinose isomerase activity
G5C61_RS05420	COG1609	Transcriptional regulator
G5C61_RS05425	COG1078	dGTPase activity
G5C61_RS05440	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G5C61_RS05445	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G5C61_RS05450	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
G5C61_RS05450	COG1918	ferrous iron import across plasma membrane
G5C61_RS05480	COG1846	Transcriptional regulator
G5C61_RS05515	COG1388	LysM domain
G5C61_RS05515	COG0791	NLP P60 protein
G5C61_RS05520	COG2258	MOSC domain
G5C61_RS05525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G5C61_RS05560	COG4974	Belongs to the 'phage' integrase family
G5C61_RS05595	COG1309	transcriptional regulator
G5C61_RS05600	COG3844	kynureninase activity
G5C61_RS05605	COG1113	amino acid transport
G5C61_RS05610	COG3483	tryptophan 2,3-dioxygenase activity
G5C61_RS05615	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G5C61_RS05620	COG1942	4-Oxalocrotonate Tautomerase
G5C61_RS05650	COG0251	oxidation-reduction process
G5C61_RS05665	COG0431	NADPH-dependent FMN reductase
G5C61_RS05670	COG0196	riboflavin kinase activity
G5C61_RS05675	COG2368	4-hydroxyphenylacetate
G5C61_RS05695	COG0789	Transcriptional regulator
G5C61_RS05730	COG5646	InterPro IPR014922
G5C61_RS05780	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
G5C61_RS05785	COG0494	nUDIX hydrolase
G5C61_RS05795	COG3764	Sortase (surface protein transpeptidase)
G5C61_RS05810	COG2807	transmembrane transport
G5C61_RS05815	COG0583	DNA-binding transcription factor activity
G5C61_RS05825	COG2318	DinB family
G5C61_RS05865	COG2271	Major facilitator Superfamily
G5C61_RS05870	COG4948	Mandelate Racemase Muconate Lactonizing
G5C61_RS05880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS05885	COG1414	Transcriptional regulator
G5C61_RS05905	COG2190	(PTS) system
G5C61_RS05905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS05905	COG1263	PTS System
G5C61_RS05910	COG1469	GTP cyclohydrolase I activity
G5C61_RS05920	COG0523	cobalamin synthesis protein
G5C61_RS05930	COG0717	Belongs to the dCTP deaminase family
G5C61_RS05935	COG1121	(ABC) transporter
G5C61_RS05940	COG0803	Belongs to the bacterial solute-binding protein 9 family
G5C61_RS05945	COG0523	cobalamin synthesis protein
G5C61_RS05965	COG1942	4-Oxalocrotonate Tautomerase
G5C61_RS05970	COG0583	DNA-binding transcription factor activity
G5C61_RS06005	COG2267	carboxylic ester hydrolase activity
G5C61_RS06015	COG1335	isochorismatase
G5C61_RS06025	COG0346	lactoylglutathione lyase activity
G5C61_RS06030	COG2259	Doxx family
G5C61_RS06045	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G5C61_RS06065	COG0039	L-malate dehydrogenase activity
G5C61_RS06075	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
G5C61_RS06095	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS06095	COG1454	alcohol dehydrogenase
G5C61_RS06105	COG4302	ethanolamine ammonia-lyase activity
G5C61_RS06110	COG4303	Ethanolamine ammonia lyase large subunit
G5C61_RS06120	COG4917	ethanolamine utilization protein
G5C61_RS06130	COG3192	ethanolamine utilization protein
G5C61_RS06160	COG1309	transcriptional regulator
G5C61_RS06165	COG2076	Multidrug Resistance protein
G5C61_RS06180	COG0477	Major facilitator Superfamily
G5C61_RS06190	COG0477	Major facilitator Superfamily
G5C61_RS06195	COG1309	transcriptional regulator
G5C61_RS06215	COG0156	8-amino-7-oxononanoate synthase activity
G5C61_RS06220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G5C61_RS06230	COG1378	Sugar-specific transcriptional regulator TrmB
G5C61_RS06235	COG0697	spore germination
G5C61_RS06240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS06245	COG2211	Major facilitator Superfamily
G5C61_RS06250	COG1063	alcohol dehydrogenase
G5C61_RS06255	COG0457	Tetratricopeptide repeat
G5C61_RS06285	COG1266	CAAX protease self-immunity
G5C61_RS06300	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS06305	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS06315	COG0252	asparaginase activity
G5C61_RS06335	COG1695	Transcriptional regulator
G5C61_RS06345	COG0583	DNA-binding transcription factor activity
G5C61_RS06355	COG2814	Major facilitator Superfamily
G5C61_RS06365	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
G5C61_RS06375	COG0281	malic enzyme
G5C61_RS06380	COG2404	hydrolase activity, acting on ester bonds
G5C61_RS06405	COG0546	phosphoglycolate phosphatase activity
G5C61_RS06440	COG1621	beta-fructofuranosidase activity
G5C61_RS06445	COG0366	Alpha amylase catalytic
G5C61_RS06450	COG1609	Transcriptional regulator
G5C61_RS06460	COG0697	spore germination
G5C61_RS06470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS06475	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS06540	COG0303	'Molybdopterin
G5C61_RS06550	COG0521	Mo-molybdopterin cofactor biosynthetic process
G5C61_RS06555	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G5C61_RS06580	COG2828	Protein conserved in bacteria
G5C61_RS06585	COG0583	DNA-binding transcription factor activity
G5C61_RS06590	COG2851	Citrate transporter
G5C61_RS06610	COG0670	Belongs to the BI1 family
G5C61_RS06630	COG0791	NLP P60 protein
G5C61_RS06635	COG2814	Major facilitator Superfamily
G5C61_RS06640	COG1846	Transcriptional regulator
G5C61_RS06660	COG1278	Cold shock
G5C61_RS06680	COG1113	amino acid transport
G5C61_RS06685	COG1113	amino acid transport
G5C61_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS06695	COG0506	proline dehydrogenase activity
G5C61_RS06700	COG3878	Protein conserved in bacteria
G5C61_RS06720	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS06760	COG5609	conserved protein (DUF2294)
G5C61_RS06800	COG1247	-acetyltransferase
G5C61_RS06820	COG0789	Transcriptional regulator
G5C61_RS06825	COG0667	Aldo Keto reductase
G5C61_RS06835	COG0789	Transcriptional regulator
G5C61_RS06860	COG1621	beta-fructofuranosidase activity
G5C61_RS06865	COG4980	gas vesicle protein
G5C61_RS06890	COG1752	Esterase of the alpha-beta hydrolase superfamily
G5C61_RS06895	COG0577	efflux transmembrane transporter activity
G5C61_RS06900	COG1136	(ABC) transporter
G5C61_RS06910	COG0642	Histidine kinase
G5C61_RS06915	COG0745	RESPONSE REGULATOR receiver
G5C61_RS06925	COG1289	transmembrane transporter activity
G5C61_RS06930	COG1937	Protein conserved in bacteria
G5C61_RS06935	COG3209	COG3209 Rhs family protein
G5C61_RS06945	COG3973	AAA domain
G5C61_RS06950	COG1024	Enoyl-CoA hydratase
G5C61_RS06955	COG1733	regulation of RNA biosynthetic process
G5C61_RS06970	COG2124	cytochrome p450
G5C61_RS06975	COG2259	Doxx family
G5C61_RS06980	COG0463	Glycosyl transferase, family 2
G5C61_RS06990	COG0463	Glycosyl transferase, family 2
G5C61_RS07005	COG1388	LysM domain
G5C61_RS07005	COG0791	NLP P60 protein
G5C61_RS07010	COG0840	transmembrane signaling receptor activity
G5C61_RS07015	COG1846	Transcriptional regulator
G5C61_RS07025	COG1595	DNA-templated transcription, initiation
G5C61_RS07030	COG0726	polysaccharide deacetylase
G5C61_RS07045	COG0833	amino acid
G5C61_RS07055	COG0405	Gamma-glutamyltransferase
G5C61_RS07075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5C61_RS07080	COG0569	domain protein
G5C61_RS07090	COG1522	sequence-specific DNA binding
G5C61_RS07100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5C61_RS07105	COG0745	RESPONSE REGULATOR receiver
G5C61_RS07110	COG2770	Histidine kinase
G5C61_RS07110	COG2205	protein histidine kinase activity
G5C61_RS07115	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G5C61_RS07120	COG1607	acyl-coa hydrolase
G5C61_RS07125	COG1802	Transcriptional regulator
G5C61_RS07130	COG0697	spore germination
G5C61_RS07140	COG0006	proline dipeptidase activity
G5C61_RS07160	COG2249	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS07165	COG5522	Integral membrane protein (intg_mem_TP0381)
G5C61_RS07175	COG1174	glycine betaine transport
G5C61_RS07180	COG1125	glycine betaine transport
G5C61_RS07180	COG0517	IMP dehydrogenase activity
G5C61_RS07195	COG2814	Major facilitator Superfamily
G5C61_RS07205	COG2205	protein histidine kinase activity
G5C61_RS07210	COG0730	response to heat
G5C61_RS07215	COG1301	dicarboxylic acid transport
G5C61_RS07250	COG1368	sulfuric ester hydrolase activity
G5C61_RS07260	COG0697	spore germination
G5C61_RS07265	COG1902	pentaerythritol trinitrate reductase activity
G5C61_RS07280	COG1113	amino acid transport
G5C61_RS07285	COG5505	Protein of unknown function (DUF819)
G5C61_RS07290	COG1309	transcriptional regulator
G5C61_RS07300	COG0583	DNA-binding transcription factor activity
G5C61_RS07305	COG0730	response to heat
G5C61_RS07315	COG2910	NAD(P)H-binding
G5C61_RS07325	COG1285	pathogenesis
G5C61_RS07330	COG2226	methyltransferase
G5C61_RS07335	COG4195	phage-related replication protein
G5C61_RS07345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS07360	COG1113	amino acid transport
G5C61_RS07390	COG0463	Glycosyl transferase, family 2
G5C61_RS07415	COG2514	catechol 2,3-dioxygenase activity
G5C61_RS07435	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS07440	COG1115	amino acid carrier protein
G5C61_RS07450	COG0385	Bile acid
G5C61_RS07455	COG0668	transmembrane transport
G5C61_RS07460	COG2340	Cysteine-rich secretory protein family
G5C61_RS07465	COG1253	flavin adenine dinucleotide binding
G5C61_RS07475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G5C61_RS07480	COG0589	response to stress
G5C61_RS07490	COG0205	6-phosphofructokinase activity
G5C61_RS07495	COG0791	NLP P60 protein
G5C61_RS07495	COG1388	LysM domain
G5C61_RS07505	COG0432	Pfam Uncharacterised protein family UPF0047
G5C61_RS07510	COG0697	spore germination
G5C61_RS07515	COG0814	amino acid
G5C61_RS07540	COG1131	(ABC) transporter
G5C61_RS07555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS07570	COG0584	glycerophosphoryl diester phosphodiesterase
G5C61_RS07580	COG1131	(ABC) transporter
G5C61_RS07610	COG1263	PTS System
G5C61_RS07610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS07615	COG3711	transcriptional antiterminator
G5C61_RS07620	COG2190	(PTS) system
G5C61_RS07625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G5C61_RS07640	COG0772	Belongs to the SEDS family
G5C61_RS07645	COG0659	secondary active sulfate transmembrane transporter activity
G5C61_RS07650	COG0813	purine-nucleoside phosphorylase activity
G5C61_RS07665	COG0671	phosphoesterase, PA-phosphatase related
G5C61_RS07670	COG4326	sporulation control protein
G5C61_RS07675	COG2815	serine threonine protein kinase
G5C61_RS07675	COG0515	serine threonine protein kinase
G5C61_RS07700	COG4479	Belongs to the UPF0346 family
G5C61_RS07705	COG3594	Acyltransferase
G5C61_RS07720	COG1509	lysine 2,3-aminomutase activity
G5C61_RS07725	COG0456	acetyltransferase
G5C61_RS07730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5C61_RS07735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5C61_RS07740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G5C61_RS07745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5C61_RS07750	COG1301	dicarboxylic acid transport
G5C61_RS07760	COG4191	Histidine kinase
G5C61_RS07790	COG2755	lipolytic protein G-D-S-L family
G5C61_RS07795	COG1999	signal sequence binding
G5C61_RS07805	COG1307	EDD domain protein, DegV family
G5C61_RS07815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G5C61_RS07825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G5C61_RS07830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G5C61_RS07835	COG0788	formyltetrahydrofolate deformylase activity
G5C61_RS07840	COG1070	Carbohydrate kinase
G5C61_RS07870	COG0076	glutamate decarboxylase activity
G5C61_RS07890	COG0415	Belongs to the DNA photolyase family
G5C61_RS07895	COG3852	Histidine kinase
G5C61_RS07920	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS07930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G5C61_RS07940	COG4846	Membrane protein involved in cytochrome C biogenesis
G5C61_RS07945	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
G5C61_RS07950	COG0785	Cytochrome C biogenesis protein
G5C61_RS07960	COG1132	(ABC) transporter
G5C61_RS07965	COG1132	(ABC) transporter
G5C61_RS07985	COG4224	UPF0291 protein
G5C61_RS07990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G5C61_RS08010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G5C61_RS08015	COG0531	amino acid
G5C61_RS08025	COG0174	glutamine synthetase
G5C61_RS08030	COG0789	Transcriptional regulator
G5C61_RS08035	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
G5C61_RS08040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G5C61_RS08045	COG2860	membrane
G5C61_RS08050	COG0464	growth
G5C61_RS08060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G5C61_RS08070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G5C61_RS08075	COG0531	amino acid
G5C61_RS08085	COG4550	Control of competence regulator ComK, YlbF/YmcA
G5C61_RS08090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G5C61_RS08095	COG1013	pyruvate-flavodoxin oxidoreductase activity
G5C61_RS08100	COG0674	pyruvate-flavodoxin oxidoreductase activity
G5C61_RS08100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G5C61_RS08115	COG2359	stage V sporulation protein S
G5C61_RS08120	COG1692	metallophosphoesterase
G5C61_RS08130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G5C61_RS08135	COG1058	Belongs to the CinA family
G5C61_RS08135	COG1546	Belongs to the CinA family
G5C61_RS08140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G5C61_RS08145	COG1426	Protein conserved in bacteria
G5C61_RS08160	COG0300	oxidoreductase activity
G5C61_RS08165	COG0612	Peptidase, M16
G5C61_RS08170	COG0612	Peptidase, M16
G5C61_RS08195	COG2188	Transcriptional regulator
G5C61_RS08200	COG4980	gas vesicle protein
G5C61_RS08200	COG1674	ftsk spoiiie
G5C61_RS08210	COG0740	serine-type endopeptidase activity
G5C61_RS08215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G5C61_RS08225	COG0527	aspartate kinase activity
G5C61_RS08230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G5C61_RS08235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G5C61_RS08240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5C61_RS08245	COG1873	PFAM PRC-barrel domain
G5C61_RS08250	COG0612	Peptidase, M16
G5C61_RS08255	COG0726	polysaccharide deacetylase
G5C61_RS08260	COG1185	polyribonucleotide nucleotidyltransferase activity
G5C61_RS08265	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G5C61_RS08270	COG0196	riboflavin kinase activity
G5C61_RS08280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G5C61_RS08285	COG1550	Protein conserved in bacteria
G5C61_RS08295	COG1358	cellular component organization or biogenesis
G5C61_RS08300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
G5C61_RS08305	COG0195	Participates in both transcription termination and antitermination
G5C61_RS08310	COG0779	Required for maturation of 30S ribosomal subunits
G5C61_RS08315	COG2176	DNA-directed DNA polymerase activity
G5C61_RS08320	COG0442	prolyl-tRNA aminoacylation
G5C61_RS08325	COG0750	zinc metalloprotease
G5C61_RS08335	COG4589	Belongs to the CDS family
G5C61_RS08345	COG0233	cytoplasmic translational termination
G5C61_RS08355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G5C61_RS08370	COG1191	sigma factor activity
G5C61_RS08375	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G5C61_RS08380	COG0835	chemotaxis
G5C61_RS08385	COG0643	Histidine kinase
G5C61_RS08385	COG2198	Histidine kinase
G5C61_RS08390	COG2201	protein-glutamate methylesterase activity
G5C61_RS08395	COG0455	bacterial-type flagellum organization
G5C61_RS08400	COG1419	protein localization to endoplasmic reticulum
G5C61_RS08405	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G5C61_RS08410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G5C61_RS08415	COG1684	flagellar biosynthetic protein fliR
G5C61_RS08420	COG1987	bacterial-type flagellum assembly
G5C61_RS08425	COG1338	Plays a role in the flagellum-specific transport system
G5C61_RS08430	COG3190	flagellar
G5C61_RS08435	COG2201	protein-glutamate methylesterase activity
G5C61_RS08440	COG1776	CheC inhibitor of MCP methylation
G5C61_RS08440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5C61_RS08445	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5C61_RS08455	COG1582	Flagellar protein (FlbD)
G5C61_RS08460	COG4786	Flagellar basal body rod
G5C61_RS08465	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G5C61_RS08480	COG2882	bacterial-type flagellum organization
G5C61_RS08485	COG1157	protein secretion by the type III secretion system
G5C61_RS08490	COG1317	bacterial-type flagellum organization
G5C61_RS08495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G5C61_RS08500	COG1766	The M ring may be actively involved in energy transduction
G5C61_RS08505	COG1677	Flagellar hook-basal body complex protein FliE
G5C61_RS08510	COG1558	bacterial-type flagellum-dependent cell motility
G5C61_RS08515	COG1815	bacterial-type flagellum-dependent cell motility
G5C61_RS08520	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G5C61_RS08525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G5C61_RS08535	COG4974	Belongs to the 'phage' integrase family
G5C61_RS08540	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G5C61_RS08545	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G5C61_RS08550	COG0758	DNA mediated transformation
G5C61_RS08555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G5C61_RS08560	COG0045	succinate-CoA ligase (ADP-forming) activity
G5C61_RS08580	COG0335	large ribosomal subunit rRNA binding
G5C61_RS08590	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G5C61_RS08600	COG1837	Belongs to the UPF0109 family
G5C61_RS08605	COG0228	four-way junction DNA binding
G5C61_RS08610	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G5C61_RS08620	COG0552	protein localization to endoplasmic reticulum
G5C61_RS08625	COG1196	nuclear chromosome segregation
G5C61_RS08630	COG0571	ribonuclease III activity
G5C61_RS08640	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS08645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G5C61_RS08650	COG0416	fatty acid biosynthetic process
G5C61_RS08655	COG1349	DNA-binding transcription factor activity
G5C61_RS08660	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G5C61_RS08665	COG1760	l-serine dehydratase
G5C61_RS08670	COG1760	l-serine dehydratase
G5C61_RS08680	COG1461	Dihydroxyacetone kinase
G5C61_RS08685	COG1302	Protein conserved in bacteria
G5C61_RS08690	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G5C61_RS08700	COG1564	THIamine pyrophosphokinase
G5C61_RS08705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G5C61_RS08710	COG1162	GTPase activity
G5C61_RS08715	COG0515	serine threonine protein kinase
G5C61_RS08715	COG2815	serine threonine protein kinase
G5C61_RS08720	COG0631	protein serine/threonine phosphatase activity
G5C61_RS08730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G5C61_RS08730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G5C61_RS08735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G5C61_RS08745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G5C61_RS08750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G5C61_RS08755	COG1758	RNA polymerase activity
G5C61_RS08760	COG0194	GDP metabolic process
G5C61_RS08765	COG2052	Domain of unknown function (DUF370)
G5C61_RS08770	COG1561	YicC-like family, N-terminal region
G5C61_RS08775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G5C61_RS08785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G5C61_RS08800	COG0543	2 iron, 2 sulfur cluster binding
G5C61_RS08815	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G5C61_RS08820	COG0540	Belongs to the ATCase OTCase family
G5C61_RS08830	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
G5C61_RS08835	COG0564	pseudouridine synthase activity
G5C61_RS08840	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G5C61_RS08855	COG3599	regulation of cell shape
G5C61_RS08860	COG2302	S4 RNA-binding domain
G5C61_RS08865	COG0762	integral membrane protein
G5C61_RS08870	COG1799	cell septum assembly
G5C61_RS08875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G5C61_RS08885	COG1873	PFAM PRC-barrel domain
G5C61_RS08890	COG1191	sigma factor activity
G5C61_RS08895	COG1191	sigma factor activity
G5C61_RS08905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G5C61_RS08910	COG0849	cell division
G5C61_RS08915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G5C61_RS08920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G5C61_RS08925	COG0772	Belongs to the SEDS family
G5C61_RS08930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G5C61_RS08935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G5C61_RS08940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G5C61_RS08945	COG0768	penicillin binding
G5C61_RS08955	COG4839	cell division protein FtsL
G5C61_RS08965	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
G5C61_RS08975	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5C61_RS08980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5C61_RS08985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G5C61_RS08990	COG0439	Biotin carboxylase
G5C61_RS08995	COG0454	-acetyltransferase
G5C61_RS09005	COG1024	Enoyl-CoA hydratase
G5C61_RS09010	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G5C61_RS09015	COG1399	metal-binding, possibly nucleic acid-binding protein
G5C61_RS09020	COG1323	Belongs to the UPF0348 family
G5C61_RS09025	COG3480	Lon protease (S16) C-terminal proteolytic domain
G5C61_RS09030	COG1752	Esterase of the alpha-beta hydrolase superfamily
G5C61_RS09035	COG3314	Sporulation integral membrane protein YlbJ
G5C61_RS09040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G5C61_RS09045	COG0742	ribosomal rna small subunit methyltransferase
G5C61_RS09055	COG4471	UPF0298 protein
G5C61_RS09065	COG3679	Belongs to the UPF0342 family
G5C61_RS09085	COG4347	Protein of unknown function (DUF1405)
G5C61_RS09095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G5C61_RS09110	COG5582	Belongs to the UPF0302 family
G5C61_RS09115	COG0457	Tetratricopeptide repeat
G5C61_RS09120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G5C61_RS09125	COG0287	Prephenate dehydrogenase
G5C61_RS09130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G5C61_RS09135	COG0159	tryptophan synthase activity
G5C61_RS09145	COG0135	phosphoribosylanthranilate isomerase activity
G5C61_RS09150	COG0134	indole-3-glycerol-phosphate synthase activity
G5C61_RS09155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G5C61_RS09165	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G5C61_RS09170	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G5C61_RS09175	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G5C61_RS09180	COG0105	UTP biosynthetic process
G5C61_RS09185	COG0142	geranyltranstransferase activity
G5C61_RS09190	COG2226	methyltransferase
G5C61_RS09195	COG0142	geranyltranstransferase activity
G5C61_RS09205	COG0302	gtp cyclohydrolase
G5C61_RS09210	COG0776	regulation of translation
G5C61_RS09215	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G5C61_RS09250	COG2271	Major facilitator Superfamily
G5C61_RS09255	COG1304	FMN binding
G5C61_RS09260	COG0539	negative regulation of cytoplasmic translation
G5C61_RS09270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G5C61_RS09285	COG2959	enzyme of heme biosynthesis
G5C61_RS09290	COG3409	Peptidoglycan-binding domain 1 protein
G5C61_RS09290	COG3773	Cell wall hydrolase
G5C61_RS09295	COG2339	peptidase activity
G5C61_RS09300	COG0252	asparaginase activity
G5C61_RS09305	COG0492	ferredoxin-NADP+ reductase activity
G5C61_RS09310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G5C61_RS09315	COG4862	establishment of competence for transformation
G5C61_RS09320	COG0789	Transcriptional regulator
G5C61_RS09325	COG1408	metallophosphoesterase
G5C61_RS09340	COG1266	CAAX protease self-immunity
G5C61_RS09345	COG0514	ATP-dependent DNA helicase (RecQ)
G5C61_RS09355	COG1141	Ferredoxin
G5C61_RS09360	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
G5C61_RS09365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5C61_RS09370	COG0739	heme binding
G5C61_RS09375	COG5002	protein histidine kinase activity
G5C61_RS09380	COG0745	RESPONSE REGULATOR receiver
G5C61_RS09385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5C61_RS09390	COG1333	cytochrome c biogenesis protein
G5C61_RS09395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS09400	COG1187	pseudouridine synthase activity
G5C61_RS09405	COG0700	Nucleoside recognition
G5C61_RS09410	COG2715	membrane protein required for spore maturation
G5C61_RS09415	COG1686	Belongs to the peptidase S11 family
G5C61_RS09420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G5C61_RS09425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G5C61_RS09435	COG1547	Domain of unknown function (DUF309)
G5C61_RS09445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G5C61_RS09450	COG4086	secreted protein
G5C61_RS09460	COG0697	spore germination
G5C61_RS09475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G5C61_RS09510	COG1686	Belongs to the peptidase S11 family
G5C61_RS09525	COG4974	Belongs to the 'phage' integrase family
G5C61_RS09535	COG0735	belongs to the Fur family
G5C61_RS09540	COG1300	Membrane
G5C61_RS09545	COG0494	nUDIX hydrolase
G5C61_RS09555	COG0667	Aldo Keto reductase
G5C61_RS09565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5C61_RS09570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G5C61_RS09580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5C61_RS09585	COG1073	alpha beta
G5C61_RS09600	COG0300	oxidoreductase activity
G5C61_RS09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS09610	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G5C61_RS09615	COG1902	pentaerythritol trinitrate reductase activity
G5C61_RS09625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5C61_RS09630	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS09635	COG2508	Transcriptional regulator
G5C61_RS09655	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G5C61_RS09655	COG0167	dihydroorotate dehydrogenase activity
G5C61_RS09660	COG0493	'glutamate synthase
G5C61_RS09665	COG2195	Cleaves the N-terminal amino acid of tripeptides
G5C61_RS09670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G5C61_RS09685	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS09690	COG4129	membrane
G5C61_RS09695	COG1126	abc transporter atp-binding protein
G5C61_RS09700	COG0765	amino acid transport
G5C61_RS09705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS09715	COG1703	isobutyryl-CoA mutase activity
G5C61_RS09720	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS09720	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS09725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS09725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5C61_RS09735	COG0022	dehydrogenase e1 component
G5C61_RS09740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G5C61_RS09745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5C61_RS09760	COG0280	phosphate acetyltransferase
G5C61_RS09765	COG3829	transcription factor binding
G5C61_RS09765	COG3290	protein histidine kinase activity
G5C61_RS09775	COG0584	glycerophosphoryl diester phosphodiesterase
G5C61_RS09780	COG3093	addiction module antidote protein HigA
G5C61_RS09785	COG3104	oligopeptide transport
G5C61_RS09790	COG0745	RESPONSE REGULATOR receiver
G5C61_RS09795	COG0750	zinc metalloprotease
G5C61_RS09800	COG0497	DNA recombination
G5C61_RS09810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
G5C61_RS09825	COG1722	exodeoxyribonuclease VII activity
G5C61_RS09835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G5C61_RS09840	COG1302	Protein conserved in bacteria
G5C61_RS09845	COG0439	Biotin carboxylase
G5C61_RS09850	COG0511	ligase activity, forming carbon-carbon bonds
G5C61_RS09890	COG3854	ATPases associated with a variety of cellular activities
G5C61_RS09900	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G5C61_RS09905	COG0006	proline dipeptidase activity
G5C61_RS09910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G5C61_RS09920	COG3872	metal-dependent enzyme
G5C61_RS09930	COG1752	Esterase of the alpha-beta hydrolase superfamily
G5C61_RS09935	COG1321	iron dependent repressor
G5C61_RS09940	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5C61_RS09955	COG0095	Lipoate-protein ligase
G5C61_RS09960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5C61_RS09970	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G5C61_RS09975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G5C61_RS09980	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G5C61_RS10010	COG4970	Tfp pilus assembly protein FimT
G5C61_RS10015	COG4537	Required for transformation and DNA binding
G5C61_RS10020	COG1459	type II secretion system
G5C61_RS10025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G5C61_RS10030	COG1393	Belongs to the ArsC family
G5C61_RS10040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS10050	COG2866	Carboxypeptidase
G5C61_RS10055	COG1940	carbohydrate kinase activity
G5C61_RS10060	COG4483	Protein conserved in bacteria
G5C61_RS10065	COG0457	Tetratricopeptide repeat
G5C61_RS10065	COG0705	Rhomboid family
G5C61_RS10080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G5C61_RS10090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G5C61_RS10105	COG0704	Plays a role in the regulation of phosphate uptake
G5C61_RS10120	COG0477	Major facilitator Superfamily
G5C61_RS10155	COG2839	Protein conserved in bacteria
G5C61_RS10165	COG2814	Major facilitator Superfamily
G5C61_RS10170	COG1388	LysM domain
G5C61_RS10175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G5C61_RS10180	COG4709	membrane
G5C61_RS10185	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
G5C61_RS10190	COG0735	belongs to the Fur family
G5C61_RS10195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5C61_RS10200	COG1121	(ABC) transporter
G5C61_RS10210	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G5C61_RS10215	COG0513	Belongs to the DEAD box helicase family
G5C61_RS10225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G5C61_RS10230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G5C61_RS10235	COG2384	SAM-dependent methyltransferase
G5C61_RS10240	COG2010	Cytochrome c
G5C61_RS10245	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS10250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G5C61_RS10255	COG0358	DNA primase activity
G5C61_RS10260	COG1671	Belongs to the UPF0178 family
G5C61_RS10265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G5C61_RS10270	COG0517	IMP dehydrogenase activity
G5C61_RS10285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G5C61_RS10290	COG0295	cytidine deaminase activity
G5C61_RS10295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G5C61_RS10305	COG1480	7TM receptor with intracellular HD hydrolase
G5C61_RS10310	COG1702	phosphate starvation-inducible protein PhoH
G5C61_RS10335	COG1030	water channel activity
G5C61_RS10340	COG1610	YqeY-like protein
G5C61_RS10350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G5C61_RS10355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G5C61_RS10360	COG2264	protein methyltransferase activity
G5C61_RS10375	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G5C61_RS10380	COG1420	regulation of RNA biosynthetic process
G5C61_RS10385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G5C61_RS10390	COG0481	GTPase activity
G5C61_RS10400	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G5C61_RS10405	COG0268	Binds directly to 16S ribosomal RNA
G5C61_RS10410	COG1466	dna polymerase III delta subunit
G5C61_RS10420	COG0658	competence protein
G5C61_RS10420	COG2333	competence protein COMEC
G5C61_RS10425	COG2131	deaminase
G5C61_RS10430	COG1555	photosystem II stabilization
G5C61_RS10430	COG1596	polysaccharide export
G5C61_RS10435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G5C61_RS10440	COG2226	methyltransferase
G5C61_RS10445	COG0799	negative regulation of ribosome biogenesis
G5C61_RS10450	COG1713	HD superfamily hydrolase involved in NAD metabolism
G5C61_RS10455	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G5C61_RS10460	COG1534	Rna-binding protein
G5C61_RS10465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G5C61_RS10470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G5C61_RS10475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
G5C61_RS10485	COG0688	phosphatidylethanolamine metabolic process
G5C61_RS10490	COG1183	phosphatidylcholine synthase activity
G5C61_RS10515	COG0626	cystathionine gamma-synthase activity
G5C61_RS10520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5C61_RS10525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G5C61_RS10530	COG2226	methyltransferase
G5C61_RS10545	COG0768	penicillin binding
G5C61_RS10550	COG1335	isochorismatase
G5C61_RS10555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G5C61_RS10560	COG0572	uridine kinase
G5C61_RS10575	COG4122	O-methyltransferase activity
G5C61_RS10580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G5C61_RS10585	COG3906	Belongs to the UPF0473 family
G5C61_RS10595	COG4472	Bacterial protein of unknown function (DUF965)
G5C61_RS10605	COG0628	permease
G5C61_RS10620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G5C61_RS10630	COG0482	sulfurtransferase activity
G5C61_RS10635	COG1104	cysteine desulfurase activity
G5C61_RS10640	COG1959	2 iron, 2 sulfur cluster binding
G5C61_RS10645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G5C61_RS10650	COG0581	inorganic phosphate transmembrane transporter activity
G5C61_RS10655	COG0573	inorganic phosphate transmembrane transporter activity
G5C61_RS10660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G5C61_RS10665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G5C61_RS10675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G5C61_RS10680	COG0124	histidyl-tRNA synthetase
G5C61_RS10690	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS10695	COG1490	D-aminoacyl-tRNA deacylase activity
G5C61_RS10700	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G5C61_RS10705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G5C61_RS10710	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G5C61_RS10710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G5C61_RS10715	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5C61_RS10715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G5C61_RS10725	COG2244	polysaccharide biosynthetic process
G5C61_RS10730	COG2323	membrane
G5C61_RS10740	COG1862	Preprotein translocase
G5C61_RS10745	COG0343	queuine tRNA-ribosyltransferase activity
G5C61_RS10750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G5C61_RS10760	COG2255	four-way junction helicase activity
G5C61_RS10765	COG0632	four-way junction helicase activity
G5C61_RS10790	COG1388	LysM domain
G5C61_RS10795	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G5C61_RS10800	COG0157	Belongs to the NadC ModD family
G5C61_RS10805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G5C61_RS10810	COG1104	cysteine desulfurase activity
G5C61_RS10815	COG1827	regulation of RNA biosynthetic process
G5C61_RS10820	COG0077	Prephenate dehydratase
G5C61_RS10825	COG4492	Belongs to the UPF0735 family
G5C61_RS10830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G5C61_RS10835	COG3290	protein histidine kinase activity
G5C61_RS10845	COG2868	ribosomal protein
G5C61_RS10855	COG1530	ribonuclease E activity
G5C61_RS10860	COG1994	Peptidase M50
G5C61_RS10865	COG0739	heme binding
G5C61_RS10870	COG2894	cell division
G5C61_RS10875	COG0850	regulation of cytokinetic process
G5C61_RS10880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G5C61_RS10885	COG1792	Involved in formation and maintenance of cell shape
G5C61_RS10890	COG1077	Cell shape determining protein MreB Mrl
G5C61_RS10895	COG2003	Belongs to the UPF0758 family
G5C61_RS10900	COG0424	maF-like protein
G5C61_RS10910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G5C61_RS10920	COG2322	membrane
G5C61_RS10925	COG0285	dihydrofolate synthase activity
G5C61_RS10930	COG0525	valine-tRNA ligase activity
G5C61_RS10940	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G5C61_RS10945	COG1388	LysM domain
G5C61_RS10950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G5C61_RS10955	COG0113	porphobilinogen synthase activity
G5C61_RS10960	COG1587	Uroporphyrinogen-III synthase
G5C61_RS10965	COG0181	hydroxymethylbilane synthase activity
G5C61_RS10970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G5C61_RS10985	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G5C61_RS10990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G5C61_RS10995	COG0470	DNA polymerase III
G5C61_RS10995	COG1067	ATP-dependent peptidase activity
G5C61_RS11000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G5C61_RS11005	COG0544	peptidyl-prolyl cis-trans isomerase activity
G5C61_RS11010	COG1477	protein flavinylation
G5C61_RS11010	COG0457	Tetratricopeptide repeat
G5C61_RS11015	COG0066	3-isopropylmalate dehydratase activity
G5C61_RS11020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G5C61_RS11030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5C61_RS11035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G5C61_RS11040	COG0440	acetolactate synthase activity
G5C61_RS11045	COG0028	Belongs to the TPP enzyme family
G5C61_RS11055	COG0622	Phosphoesterase
G5C61_RS11065	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G5C61_RS11070	COG5401	PFAM Sporulation and spore germination
G5C61_RS11075	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G5C61_RS11080	COG1846	Transcriptional regulator
G5C61_RS11090	COG0306	phosphate transporter
G5C61_RS11095	COG1392	Phosphate transport regulator
G5C61_RS11100	COG0768	penicillin binding
G5C61_RS11110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS11115	COG0431	NADPH-dependent FMN reductase
G5C61_RS11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5C61_RS11125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5C61_RS11130	COG1116	anion transmembrane transporter activity
G5C61_RS11135	COG0475	glutathione-regulated potassium exporter activity
G5C61_RS11140	COG0490	domain, Protein
G5C61_RS11150	COG2197	response regulator
G5C61_RS11155	COG0824	Thioesterase
G5C61_RS11160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G5C61_RS11165	COG1053	succinate dehydrogenase
G5C61_RS11170	COG2009	succinate dehydrogenase
G5C61_RS11175	COG1719	4-vinyl reductase, 4VR
G5C61_RS11180	COG0527	aspartate kinase activity
G5C61_RS11190	COG3118	belongs to the thioredoxin family
G5C61_RS11195	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G5C61_RS11200	COG2086	electron transfer activity
G5C61_RS11205	COG1024	Enoyl-CoA hydratase
G5C61_RS11210	COG1309	transcriptional regulator
G5C61_RS11215	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS11220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5C61_RS11225	COG3766	membrane
G5C61_RS11230	COG1193	negative regulation of DNA recombination
G5C61_RS11235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G5C61_RS11235	COG1796	DNA polymerase
G5C61_RS11240	COG1286	toxin biosynthetic process
G5C61_RS11245	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
G5C61_RS11255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5C61_RS11255	COG0072	phenylalanine-tRNA ligase activity
G5C61_RS11260	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G5C61_RS11265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G5C61_RS11275	COG1363	Peptidase, m42
G5C61_RS11295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G5C61_RS11300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G5C61_RS11305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G5C61_RS11310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G5C61_RS11320	COG1484	DNA-dependent DNA replication
G5C61_RS11325	COG3611	Membrane attachment protein
G5C61_RS11330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G5C61_RS11340	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
G5C61_RS11345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G5C61_RS11350	COG0237	dephospho-CoA kinase activity
G5C61_RS11355	COG1971	Probably functions as a manganese efflux pump
G5C61_RS11360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G5C61_RS11365	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5C61_RS11365	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5C61_RS11370	COG5002	protein histidine kinase activity
G5C61_RS11375	COG0745	RESPONSE REGULATOR receiver
G5C61_RS11385	COG0039	L-malate dehydrogenase activity
G5C61_RS11390	COG0538	isocitrate dehydrogenase activity
G5C61_RS11395	COG0372	Belongs to the citrate synthase family
G5C61_RS11400	COG2707	UPF0756 membrane protein
G5C61_RS11405	COG0628	permease
G5C61_RS11410	COG3030	protein affecting phage T7 exclusion by the F plasmid
G5C61_RS11420	COG0825	malonyl-CoA metabolic process
G5C61_RS11425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G5C61_RS11430	COG2186	Transcriptional regulator
G5C61_RS11435	COG0281	malic enzyme
G5C61_RS11440	COG0587	DNA-directed DNA polymerase activity
G5C61_RS11455	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G5C61_RS11465	COG4109	DRTGG domain
G5C61_RS11480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G5C61_RS11495	COG0165	Argininosuccinate lyase
G5C61_RS11500	COG0137	argininosuccinate synthase activity
G5C61_RS11515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G5C61_RS11520	COG0827	DNA restriction-modification system
G5C61_RS11525	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G5C61_RS11530	COG3874	Sporulation protein YtfJ
G5C61_RS11540	COG1714	RDD family
G5C61_RS11545	COG0616	signal peptide processing
G5C61_RS11550	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G5C61_RS11555	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G5C61_RS11565	COG0301	tRNA thio-modification
G5C61_RS11570	COG1104	cysteine desulfurase activity
G5C61_RS11575	COG1114	Component of the transport system for branched-chain amino acids
G5C61_RS11580	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
G5C61_RS11585	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G5C61_RS11590	COG1309	transcriptional regulator
G5C61_RS11595	COG1956	GAF domain-containing protein
G5C61_RS11610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5C61_RS11615	COG0454	-acetyltransferase
G5C61_RS11620	COG0517	IMP dehydrogenase activity
G5C61_RS11625	COG0123	including yeast histone deacetylase and acetoin utilization protein
G5C61_RS11645	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G5C61_RS11645	COG1605	Chorismate mutase
G5C61_RS11650	COG3118	belongs to the thioredoxin family
G5C61_RS11655	COG4980	gas vesicle protein
G5C61_RS11670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G5C61_RS11680	COG1674	ftsk spoiiie
G5C61_RS11685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G5C61_RS11690	COG4848	Belongs to the UPF0354 family
G5C61_RS11695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS11700	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
G5C61_RS11705	COG1363	Peptidase, m42
G5C61_RS11710	COG5584	Small secreted protein
G5C61_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS11720	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G5C61_RS11730	COG0510	thiamine kinase activity
G5C61_RS11735	COG1523	belongs to the glycosyl hydrolase 13 family
G5C61_RS11745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G5C61_RS11750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5C61_RS11755	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5C61_RS11760	COG1349	DNA-binding transcription factor activity
G5C61_RS11765	COG1187	pseudouridine synthase activity
G5C61_RS11770	COG2244	polysaccharide biosynthetic process
G5C61_RS11775	COG2081	HI0933 family
G5C61_RS11785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G5C61_RS11790	COG0495	leucyl-tRNA aminoacylation
G5C61_RS11800	COG2610	gluconate transmembrane transporter activity
G5C61_RS11805	COG2814	Major facilitator Superfamily
G5C61_RS11820	COG1242	4 iron, 4 sulfur cluster binding
G5C61_RS11825	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
G5C61_RS11835	COG2267	carboxylic ester hydrolase activity
G5C61_RS11840	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G5C61_RS11845	COG0671	phosphoesterase, PA-phosphatase related
G5C61_RS11850	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS11850	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G5C61_RS11855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G5C61_RS11860	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G5C61_RS11870	COG1506	peptidase
G5C61_RS11875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5C61_RS11880	COG1116	anion transmembrane transporter activity
G5C61_RS11885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5C61_RS11890	COG0494	nUDIX hydrolase
G5C61_RS11900	COG4824	toxin secretion phage lysis holin
G5C61_RS11905	COG0783	Belongs to the Dps family
G5C61_RS11915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G5C61_RS11920	COG0288	reversible hydration of carbon dioxide
G5C61_RS11925	COG0523	cobalamin synthesis protein
G5C61_RS11935	COG0254	rRNA binding
G5C61_RS11940	COG1271	oxidase subunit
G5C61_RS11945	COG1294	oxidase, subunit
G5C61_RS11950	COG0716	FMN binding
G5C61_RS11975	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5C61_RS11980	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G5C61_RS11985	COG4948	Mandelate Racemase Muconate Lactonizing
G5C61_RS11990	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS11995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G5C61_RS12000	COG0596	Alpha beta hydrolase
G5C61_RS12005	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G5C61_RS12010	COG1169	isochorismate synthase
G5C61_RS12015	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G5C61_RS12025	COG0058	SHG alpha-glucan phosphorylase activity
G5C61_RS12030	COG0297	glycogen (starch) synthase activity
G5C61_RS12035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G5C61_RS12040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G5C61_RS12170	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS12175	COG1285	pathogenesis
G5C61_RS12195	COG0529	Catalyzes the synthesis of activated sulfate
G5C61_RS12205	COG0306	phosphate transporter
G5C61_RS12220	COG0346	lactoylglutathione lyase activity
G5C61_RS12225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G5C61_RS12235	COG0166	Belongs to the GPI family
G5C61_RS12245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G5C61_RS12245	COG2111	Na H antiporter
G5C61_RS12250	COG2111	Na H antiporter
G5C61_RS12255	COG1006	Multisubunit Na H antiporter MnhC subunit
G5C61_RS12260	COG0651	ATP synthesis coupled electron transport
G5C61_RS12265	COG1863	multisubunit Na H antiporter MnhE subunit
G5C61_RS12270	COG2212	antiporter activity
G5C61_RS12275	COG1320	monovalent cation:proton antiporter activity
G5C61_RS12280	COG1979	alcohol dehydrogenase
G5C61_RS12285	COG2155	Conserved Protein
G5C61_RS12290	COG1098	S1 RNA binding domain
G5C61_RS12295	COG0436	Aminotransferase
G5C61_RS12300	COG1522	sequence-specific DNA binding
G5C61_RS12305	COG2267	carboxylic ester hydrolase activity
G5C61_RS12310	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G5C61_RS12315	COG2032	superoxide dismutase activity
G5C61_RS12330	COG5018	Exonuclease
G5C61_RS12335	COG2050	protein possibly involved in aromatic compounds catabolism
G5C61_RS12345	COG1418	mRNA catabolic process
G5C61_RS12355	COG2056	Na+-H+ antiporter family
G5C61_RS12360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G5C61_RS12365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
G5C61_RS12370	COG3584	3D domain protein
G5C61_RS12380	COG1252	NADH dehydrogenase
G5C61_RS12385	COG0492	ferredoxin-NADP+ reductase activity
G5C61_RS12395	COG0316	Belongs to the HesB IscA family
G5C61_RS12400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G5C61_RS12405	COG4844	belongs to the
G5C61_RS12410	COG1252	NADH dehydrogenase
G5C61_RS12415	COG4837	Protein of unknown function (DUF1462)
G5C61_RS12420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G5C61_RS12425	COG0083	homoserine kinase activity
G5C61_RS12430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G5C61_RS12435	COG0460	homoserine dehydrogenase
G5C61_RS12440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G5C61_RS12445	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G5C61_RS12450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G5C61_RS12455	COG0647	UMP catabolic process
G5C61_RS12460	COG2445	Protein of unknown function DUF86
G5C61_RS12470	COG4470	Protein conserved in bacteria
G5C61_RS12480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G5C61_RS12485	COG0739	heme binding
G5C61_RS12495	COG0733	neurotransmitter:sodium symporter activity
G5C61_RS12505	COG3377	Domain of unknown function (DUF1805)
G5C61_RS12510	COG1801	Protein of unknown function DUF72
G5C61_RS12515	COG0719	Fe-S assembly protein
G5C61_RS12520	COG0822	iron-sulfur transferase activity
G5C61_RS12525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G5C61_RS12530	COG0719	Fe-S assembly protein
G5C61_RS12535	COG0396	ATPase activity
G5C61_RS12540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G5C61_RS12545	COG1464	Belongs to the NlpA lipoprotein family
G5C61_RS12550	COG2011	ABC-type metal ion transport system permease component
G5C61_RS12555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G5C61_RS12560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS12565	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
G5C61_RS12575	COG0509	glycine decarboxylation via glycine cleavage system
G5C61_RS12580	COG1393	Belongs to the ArsC family
G5C61_RS12585	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS12590	COG0183	Belongs to the thiolase family
G5C61_RS12595	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5C61_RS12595	COG1024	Enoyl-CoA hydratase
G5C61_RS12620	COG1120	ATPase activity
G5C61_RS12625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS12630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS12635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5C61_RS12650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5C61_RS12655	COG1309	transcriptional regulator
G5C61_RS12665	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS12670	COG0477	Major facilitator Superfamily
G5C61_RS12675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G5C61_RS12685	COG5002	protein histidine kinase activity
G5C61_RS12685	COG3850	Histidine kinase
G5C61_RS12690	COG0745	RESPONSE REGULATOR receiver
G5C61_RS12695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G5C61_RS12700	COG0671	phosphoesterase, PA-phosphatase related
G5C61_RS12705	COG1846	Transcriptional regulator
G5C61_RS12710	COG0778	Nitroreductase
G5C61_RS12715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G5C61_RS12720	COG0314	molybdopterin synthase activity
G5C61_RS12725	COG1763	Mo-molybdopterin cofactor biosynthetic process
G5C61_RS12730	COG0303	'Molybdopterin
G5C61_RS12735	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G5C61_RS12740	COG0746	molybdenum cofactor guanylyltransferase activity
G5C61_RS12750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G5C61_RS12755	COG5609	conserved protein (DUF2294)
G5C61_RS12760	COG3383	formate dehydrogenase (NAD+) activity
G5C61_RS12765	COG2427	Protein of unknown function (DUF1641)
G5C61_RS12770	COG0725	ABC transporter, periplasmic molybdate-binding protein
G5C61_RS12775	COG4149	molybdate abc transporter
G5C61_RS12785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G5C61_RS12790	COG0557	exoribonuclease II activity
G5C61_RS12795	COG1647	Serine aminopeptidase, S33
G5C61_RS12800	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G5C61_RS12840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G5C61_RS12860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS12870	COG0391	Required for morphogenesis under gluconeogenic growth conditions
G5C61_RS12875	COG1660	Displays ATPase and GTPase activities
G5C61_RS12880	COG1051	belongs to the nudix hydrolase family
G5C61_RS12885	COG0492	ferredoxin-NADP+ reductase activity
G5C61_RS12890	COG0457	Tetratricopeptide repeat
G5C61_RS12895	COG0140	phosphoribosyl-ATP diphosphatase activity
G5C61_RS12895	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G5C61_RS12900	COG0107	imidazoleglycerol-phosphate synthase activity
G5C61_RS12905	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G5C61_RS12910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G5C61_RS12915	COG0131	Imidazoleglycerol-phosphate dehydratase
G5C61_RS12920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G5C61_RS12925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G5C61_RS12930	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G5C61_RS12935	COG0110	maltose O-acetyltransferase activity
G5C61_RS12940	COG0546	phosphoglycolate phosphatase activity
G5C61_RS12945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G5C61_RS12950	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
G5C61_RS12955	COG1950	PFAM Membrane protein of
G5C61_RS12965	COG3595	metallopeptidase activity
G5C61_RS12975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G5C61_RS12980	COG0556	nucleotide-excision repair
G5C61_RS12985	COG2204	response regulator
G5C61_RS12990	COG0506	proline dehydrogenase activity
G5C61_RS12995	COG4897	Protein conserved in bacteria
G5C61_RS13000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5C61_RS13005	COG0793	Belongs to the peptidase S41A family
G5C61_RS13005	COG3409	Peptidoglycan-binding domain 1 protein
G5C61_RS13015	COG2177	Part of the ABC transporter FtsEX involved in
G5C61_RS13020	COG2884	Cell division ATP-binding protein ftsE
G5C61_RS13025	COG0655	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS13035	COG0805	protein transport
G5C61_RS13040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5C61_RS13045	COG3540	Alkaline phosphatase
G5C61_RS13055	COG0653	protein targeting
G5C61_RS13060	COG0456	acetyltransferase
G5C61_RS13065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G5C61_RS13075	COG1516	flagellar protein fliS
G5C61_RS13080	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G5C61_RS13090	COG1113	amino acid transport
G5C61_RS13100	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS13105	COG1454	alcohol dehydrogenase
G5C61_RS13110	COG1510	regulation of RNA biosynthetic process
G5C61_RS13115	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G5C61_RS13120	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
G5C61_RS13125	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5C61_RS13130	COG4786	Flagellar basal body rod
G5C61_RS13130	COG1256	bacterial-type flagellum assembly
G5C61_RS13150	COG1040	competence protein
G5C61_RS13155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
G5C61_RS13160	COG1307	EDD domain protein, DegV family
G5C61_RS13165	COG1728	Protein conserved in bacteria
G5C61_RS13175	COG2197	response regulator
G5C61_RS13180	COG4585	Histidine kinase
G5C61_RS13185	COG1739	Uncharacterized protein family UPF0029
G5C61_RS13190	COG1316	TRANSCRIPTIONal
G5C61_RS13195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G5C61_RS13200	COG1585	Membrane protein implicated in regulation of membrane protease activity
G5C61_RS13205	COG2268	Band 7 protein
G5C61_RS13210	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
G5C61_RS13220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G5C61_RS13230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G5C61_RS13235	COG1388	LysM domain
G5C61_RS13235	COG0791	NLP P60 protein
G5C61_RS13240	COG0629	single-stranded DNA binding
G5C61_RS13260	COG4786	Flagellar basal body rod
G5C61_RS13265	COG4786	Flagellar basal body rod
G5C61_RS13270	COG1077	Cell shape determining protein MreB Mrl
G5C61_RS13275	COG1609	Transcriptional regulator
G5C61_RS13280	COG0739	heme binding
G5C61_RS13285	COG2385	sporulation resulting in formation of a cellular spore
G5C61_RS13300	COG4836	Membrane
G5C61_RS13305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G5C61_RS13310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G5C61_RS13315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G5C61_RS13320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G5C61_RS13325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G5C61_RS13330	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G5C61_RS13335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G5C61_RS13340	COG0356	it plays a direct role in the translocation of protons across the membrane
G5C61_RS13355	COG1404	Belongs to the peptidase S8 family
G5C61_RS13360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G5C61_RS13365	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G5C61_RS13380	COG0698	ribose 5-phosphate isomerase
G5C61_RS13390	COG1971	Probably functions as a manganese efflux pump
G5C61_RS13395	COG0009	L-threonylcarbamoyladenylate synthase
G5C61_RS13415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G5C61_RS13430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G5C61_RS13440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G5C61_RS13445	COG0191	fructose-bisphosphate aldolase activity
G5C61_RS13455	COG4821	SIS domain
G5C61_RS13460	COG0504	CTP synthase activity
G5C61_RS13470	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS13470	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
G5C61_RS13470	COG1703	isobutyryl-CoA mutase activity
G5C61_RS13480	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS13485	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS13490	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5C61_RS13495	COG0183	Belongs to the thiolase family
G5C61_RS13500	COG0247	lactate metabolic process
G5C61_RS13500	COG2181	nitrate reductase activity
G5C61_RS13505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS13515	COG0018	arginyl-trna synthetase
G5C61_RS13520	COG4506	Protein conserved in bacteria
G5C61_RS13525	COG0010	Belongs to the arginase family
G5C61_RS13530	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G5C61_RS13535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5C61_RS13545	COG1994	Peptidase M50
G5C61_RS13550	COG1942	4-Oxalocrotonate Tautomerase
G5C61_RS13555	COG3465	dGTPase activity
G5C61_RS13560	COG1078	dGTPase activity
G5C61_RS13565	COG4844	belongs to the
G5C61_RS13575	COG0095	Lipoate-protein ligase
G5C61_RS13580	COG0280	phosphate acetyltransferase
G5C61_RS13590	COG3773	Cell wall hydrolase
G5C61_RS13600	COG2363	Small membrane protein
G5C61_RS13610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G5C61_RS13620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5C61_RS13625	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G5C61_RS13630	COG2508	Transcriptional regulator
G5C61_RS13630	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G5C61_RS13635	COG0686	Belongs to the AlaDH PNT family
G5C61_RS13645	COG0351	phosphomethylpyrimidine kinase
G5C61_RS13650	COG0561	phosphatase activity
G5C61_RS13655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5C61_RS13660	COG2190	(PTS) system
G5C61_RS13660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS13660	COG1263	PTS System
G5C61_RS13670	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS13685	COG2076	Multidrug Resistance protein
G5C61_RS13695	COG0728	peptidoglycan biosynthetic process
G5C61_RS13710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G5C61_RS13715	COG4988	ABC transporter
G5C61_RS13720	COG1294	oxidase, subunit
G5C61_RS13725	COG1271	oxidase subunit
G5C61_RS13730	COG3610	response to peptide
G5C61_RS13735	COG2966	Psort location CytoplasmicMembrane, score
G5C61_RS13740	COG1609	Transcriptional regulator
G5C61_RS13750	COG2814	Major facilitator Superfamily
G5C61_RS13765	COG1966	Carbon starvation protein
G5C61_RS13770	COG0753	catalase activity
G5C61_RS13785	COG0471	metal ion transport
G5C61_RS13790	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G5C61_RS13805	COG5002	protein histidine kinase activity
G5C61_RS13820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G5C61_RS13825	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G5C61_RS13835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G5C61_RS13840	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G5C61_RS13845	COG4853	Protein conserved in bacteria
G5C61_RS13855	COG5002	protein histidine kinase activity
G5C61_RS13860	COG0745	RESPONSE REGULATOR receiver
G5C61_RS13885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G5C61_RS13890	COG0305	Participates in initiation and elongation during chromosome replication
G5C61_RS13900	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
G5C61_RS13910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G5C61_RS13920	COG0360	Binds together with S18 to 16S ribosomal RNA
G5C61_RS13925	COG0012	GTP binding
G5C61_RS13930	COG4481	Protein conserved in bacteria
G5C61_RS13935	COG0668	transmembrane transport
G5C61_RS13940	COG3949	Membrane
G5C61_RS13950	COG1475	DNA binding
G5C61_RS13955	COG1192	Involved in chromosome partitioning
G5C61_RS13960	COG1475	DNA binding
G5C61_RS13970	COG0445	tRNA wobble uridine modification
G5C61_RS13975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G5C61_RS13980	COG1847	R3H domain protein
G5C61_RS13985	COG0706	membrane insertase activity
G5C61_RS13990	COG0594	ribonuclease P activity
G5C61_RS13995	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G5C61_RS14000	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G5C61_RS14005	COG0592	DNA-directed DNA polymerase activity
G5C61_RS14010	COG2501	S4 domain
G5C61_RS14015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G5C61_RS14020	COG0187	DNA topoisomerase II activity
G5C61_RS14025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G5C61_RS14060	COG0517	IMP dehydrogenase activity
G5C61_RS14060	COG0516	GMP reductase activity
G5C61_RS14075	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
G5C61_RS14090	COG1428	Deoxynucleoside kinase
G5C61_RS14095	COG1428	Deoxynucleoside kinase
G5C61_RS14100	COG1388	LysM domain
G5C61_RS14100	COG3858	chitin binding
G5C61_RS14105	COG1335	isochorismatase
G5C61_RS14110	COG0590	tRNA wobble adenosine to inosine editing
G5C61_RS14120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G5C61_RS14125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G5C61_RS14130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G5C61_RS14235	COG1982	Orn Lys Arg decarboxylase major
G5C61_RS14240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G5C61_RS14245	COG3870	Protein conserved in bacteria
G5C61_RS14250	COG0470	DNA polymerase III
G5C61_RS14255	COG1774	PSP1 C-terminal conserved region
G5C61_RS14260	COG4467	Involved in initiation control of chromosome replication
G5C61_RS14265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G5C61_RS14270	COG2827	Endonuclease containing a URI domain
G5C61_RS14275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G5C61_RS14280	COG2002	toxin-antitoxin pair type II binding
G5C61_RS14290	COG0084	hydrolase, TatD family'
G5C61_RS14300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G5C61_RS14310	COG4466	Protein conserved in bacteria
G5C61_RS14325	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G5C61_RS14330	COG0251	oxidation-reduction process
G5C61_RS14335	COG2088	sporulation resulting in formation of a cellular spore
G5C61_RS14340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G5C61_RS14350	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G5C61_RS14355	COG0193	aminoacyl-tRNA hydrolase activity
G5C61_RS14365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G5C61_RS14370	COG2002	toxin-antitoxin pair type II binding
G5C61_RS14375	COG2244	polysaccharide biosynthetic process
G5C61_RS14380	COG3956	TIGRFAM MazG family protein
G5C61_RS14385	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G5C61_RS14400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G5C61_RS14405	COG1098	S1 RNA binding domain
G5C61_RS14425	COG2304	oxidoreductase activity
G5C61_RS14430	COG0515	serine threonine protein kinase
G5C61_RS14435	COG0037	tRNA processing
G5C61_RS14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G5C61_RS14450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G5C61_RS14455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G5C61_RS14460	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G5C61_RS14465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G5C61_RS14470	COG0512	Glutamine amidotransferase of anthranilate synthase
G5C61_RS14475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G5C61_RS14480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G5C61_RS14485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G5C61_RS14490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G5C61_RS14515	COG3880	PFAM UvrB UvrC protein
G5C61_RS14520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
G5C61_RS14525	COG0542	response to heat
G5C61_RS14530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G5C61_RS14535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
G5C61_RS14540	COG4956	integral membrane protein (PIN domain superfamily)
G5C61_RS14545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G5C61_RS14555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G5C61_RS14560	COG1045	serine acetyltransferase
G5C61_RS14565	COG0215	cysteine-tRNA ligase activity
G5C61_RS14575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G5C61_RS14580	COG3688	RNA-binding protein containing a PIN domain
G5C61_RS14590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G5C61_RS14595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G5C61_RS14600	COG0250	Participates in transcription elongation, termination and antitermination
G5C61_RS14605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G5C61_RS14610	COG0081	regulation of translation
G5C61_RS14615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G5C61_RS14620	COG0222	ribosome binding
G5C61_RS14625	COG2813	Specifically methylates the guanine in position
G5C61_RS14630	COG0085	RNA polymerase activity
G5C61_RS14635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G5C61_RS14640	COG1358	cellular component organization or biogenesis
G5C61_RS14645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G5C61_RS14650	COG0049	tRNA binding
G5C61_RS14660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G5C61_RS14665	COG0051	transcription antitermination factor activity, RNA binding
G5C61_RS14670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G5C61_RS14675	COG0088	Forms part of the polypeptide exit tunnel
G5C61_RS14680	COG0089	rRNA binding
G5C61_RS14685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G5C61_RS14690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G5C61_RS14695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G5C61_RS14705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G5C61_RS14710	COG0255	Belongs to the universal ribosomal protein uL29 family
G5C61_RS14715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G5C61_RS14720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G5C61_RS14735	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G5C61_RS14740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G5C61_RS14750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G5C61_RS14755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G5C61_RS14760	COG1841	ribosomal large subunit assembly
G5C61_RS14770	COG0201	protein transport
G5C61_RS14775	COG0563	adenylate kinase activity
G5C61_RS14780	COG0024	Methionine aminopeptidase
G5C61_RS14785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G5C61_RS14790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G5C61_RS14795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G5C61_RS14805	COG0202	RNA polymerase activity
G5C61_RS14810	COG0203	ribosomal protein L17
G5C61_RS14815	COG1122	ATPase activity
G5C61_RS14820	COG1122	ATPase activity
G5C61_RS14825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G5C61_RS14830	COG0101	tRNA pseudouridine synthase activity
G5C61_RS14835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G5C61_RS14850	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS14855	COG0489	protein tyrosine kinase activity
G5C61_RS14860	COG0583	DNA-binding transcription factor activity
G5C61_RS14870	COG2194	sulfuric ester hydrolase activity
G5C61_RS14875	COG0726	polysaccharide deacetylase
G5C61_RS14955	COG1595	DNA-templated transcription, initiation
G5C61_RS14960	COG5662	AntiSigma factor
G5C61_RS14965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
G5C61_RS14975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5C61_RS14980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G5C61_RS14990	COG3103	Sh3 type 3 domain protein
G5C61_RS14990	COG1388	LysM domain
G5C61_RS14990	COG0791	NLP P60 protein
G5C61_RS14995	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS14995	COG2213	PTS system mannitol-specific
G5C61_RS15000	COG3711	transcriptional antiterminator
G5C61_RS15005	COG0246	Mannitol dehydrogenase
G5C61_RS15015	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS15020	COG1970	mechanosensitive ion channel activity
G5C61_RS15025	COG1368	sulfuric ester hydrolase activity
G5C61_RS15045	COG1177	transmembrane transport
G5C61_RS15050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G5C61_RS15060	COG0745	RESPONSE REGULATOR receiver
G5C61_RS15065	COG5002	protein histidine kinase activity
G5C61_RS15080	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G5C61_RS15080	COG3976	FMN-binding domain protein
G5C61_RS15085	COG1181	Belongs to the D-alanine--D-alanine ligase family
G5C61_RS15090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G5C61_RS15095	COG0513	Belongs to the DEAD box helicase family
G5C61_RS15100	COG4294	response to UV
G5C61_RS15105	COG0705	Rhomboid family
G5C61_RS15110	COG0736	holo-[acyl-carrier-protein] synthase activity
G5C61_RS15115	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G5C61_RS15120	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G5C61_RS15125	COG0864	Transcriptional regulator
G5C61_RS15130	COG2337	Toxic component of a toxin-antitoxin (TA) module
G5C61_RS15135	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS15140	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS15145	COG2172	sigma factor antagonist activity
G5C61_RS15150	COG2208	phosphoserine phosphatase activity
G5C61_RS15155	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS15165	COG1191	sigma factor activity
G5C61_RS15170	COG2208	phosphoserine phosphatase activity
G5C61_RS15175	COG2183	response to ionizing radiation
G5C61_RS15270	COG0802	atpase or kinase
G5C61_RS15275	COG1214	PFAM Peptidase M22, glycoprotease
G5C61_RS15280	COG0456	acetyltransferase
G5C61_RS15290	COG0488	(ABC) transporter
G5C61_RS15295	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
G5C61_RS15300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5C61_RS15305	COG0805	protein transport
G5C61_RS15315	COG1266	CAAX protease self-immunity
G5C61_RS15320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G5C61_RS15330	COG2204	response regulator
G5C61_RS15340	COG1454	alcohol dehydrogenase
G5C61_RS15345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5C61_RS15350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G5C61_RS15370	COG2755	lipolytic protein G-D-S-L family
G5C61_RS15370	COG0657	acetylesterase activity
G5C61_RS15375	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS15380	COG0714	Associated with various cellular activities
G5C61_RS15385	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
G5C61_RS15390	COG1305	Transglutaminase-like
G5C61_RS15395	COG0519	Catalyzes the synthesis of GMP from XMP
G5C61_RS15395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G5C61_RS15400	COG2252	PERMEase
G5C61_RS15440	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G5C61_RS15445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G5C61_RS15450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G5C61_RS15455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G5C61_RS15460	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G5C61_RS15465	COG0047	phosphoribosylformylglycinamidine synthase activity
G5C61_RS15470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G5C61_RS15475	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G5C61_RS15480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G5C61_RS15485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G5C61_RS15490	COG0138	bifunctional purine biosynthesis protein purh
G5C61_RS15495	COG0151	Belongs to the GarS family
G5C61_RS15505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G5C61_RS15510	COG4496	protein, YerC YecD
G5C61_RS15515	COG0423	glycine-tRNA ligase activity
G5C61_RS15525	COG0210	DNA helicase
G5C61_RS15535	COG4851	CamS sex pheromone cAM373 precursor
G5C61_RS15545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G5C61_RS15550	COG0154	amidase activity
G5C61_RS15560	COG1597	lipid kinase activity
G5C61_RS15570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS15580	COG0166	Belongs to the GPI family
G5C61_RS15585	COG1744	ABC transporter substrate-binding protein PnrA-like
G5C61_RS15590	COG3852	Histidine kinase
G5C61_RS15595	COG0024	Methionine aminopeptidase
G5C61_RS15600	COG2706	6-phosphogluconolactonase activity
G5C61_RS15605	COG2070	2-Nitropropane dioxygenase
G5C61_RS15610	COG0789	Transcriptional regulator
G5C61_RS15610	COG4978	Transcriptional regulator
G5C61_RS15615	COG2814	Major facilitator Superfamily
G5C61_RS15625	COG1876	peptidase activity
G5C61_RS15630	COG1126	abc transporter atp-binding protein
G5C61_RS15635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS15640	COG0765	amino acid transport
G5C61_RS15645	COG0765	amino acid transport
G5C61_RS15650	COG1113	amino acid transport
G5C61_RS15655	COG2733	membrane
G5C61_RS15660	COG3212	peptidase
G5C61_RS15665	COG3212	peptidase
G5C61_RS15670	COG5002	protein histidine kinase activity
G5C61_RS15670	COG3850	Histidine kinase
G5C61_RS15675	COG0745	RESPONSE REGULATOR receiver
G5C61_RS15680	COG2205	protein histidine kinase activity
G5C61_RS15685	COG0745	RESPONSE REGULATOR receiver
G5C61_RS15690	COG2311	Membrane
G5C61_RS15705	COG0671	phosphoesterase, PA-phosphatase related
G5C61_RS15710	COG1764	response to oxidative stress
G5C61_RS15715	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G5C61_RS15725	COG2259	Doxx family
G5C61_RS15730	COG0693	protein deglycase activity
G5C61_RS15740	COG2318	DinB family
G5C61_RS15750	COG1115	amino acid carrier protein
G5C61_RS15765	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
G5C61_RS15770	COG0598	Magnesium transport protein CorA
G5C61_RS15775	COG3290	protein histidine kinase activity
G5C61_RS15780	COG4565	transcriptional regulatory protein
G5C61_RS15795	COG4191	Histidine kinase
G5C61_RS15800	COG0513	Belongs to the DEAD box helicase family
G5C61_RS15820	COG4842	Belongs to the WXG100 family
G5C61_RS15825	COG5417	Belongs to the EsaB family
G5C61_RS15830	COG4499	WXG100 protein secretion system (Wss), protein YukC
G5C61_RS15835	COG0433	COG0433 Predicted ATPase
G5C61_RS15835	COG1674	ftsk spoiiie
G5C61_RS15840	COG1511	domain protein
G5C61_RS15860	COG2356	endonuclease I
G5C61_RS15870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5C61_RS15885	COG0488	(ABC) transporter
G5C61_RS15895	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
G5C61_RS15905	COG1959	2 iron, 2 sulfur cluster binding
G5C61_RS15910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G5C61_RS15910	COG1017	nitric oxide dioxygenase activity
G5C61_RS15915	COG3486	L-lysine 6-monooxygenase (NADPH) activity
G5C61_RS15920	COG0693	protein deglycase activity
G5C61_RS15925	COG2340	Cysteine-rich secretory protein family
G5C61_RS15930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G5C61_RS15935	COG4840	Belongs to the UPF0435 family
G5C61_RS15940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G5C61_RS15945	COG4980	gas vesicle protein
G5C61_RS15950	COG1295	ribonuclease BN
G5C61_RS15955	COG2217	Heavy metal translocating P-type atpase
G5C61_RS15965	COG0640	Transcriptional regulator
G5C61_RS15975	COG0477	Major facilitator Superfamily
G5C61_RS15985	COG3479	Phenolic acid decarboxylase
G5C61_RS15995	COG3871	stress protein (general stress protein 26)
G5C61_RS16000	COG0387	Pfam Sodium calcium exchanger
G5C61_RS16010	COG0535	radical SAM domain protein
G5C61_RS16030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G5C61_RS16040	COG1113	amino acid transport
G5C61_RS16045	COG5002	protein histidine kinase activity
G5C61_RS16065	COG1090	epimerase
G5C61_RS16075	COG4221	oxidoreductase activity
G5C61_RS16095	COG1988	membrane-bound metal-dependent
G5C61_RS16100	COG1194	a g-specific adenine glycosylase
G5C61_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS16125	COG3557	Belongs to the UPF0374 family
G5C61_RS16130	COG1132	(ABC) transporter
G5C61_RS16135	COG4129	membrane
G5C61_RS16145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G5C61_RS16150	COG4555	ABC transporter
G5C61_RS16170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G5C61_RS16175	COG0735	belongs to the Fur family
G5C61_RS16290	COG3382	B3 4 domain protein
G5C61_RS16305	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G5C61_RS16310	COG2766	serine protein kinase
G5C61_RS16325	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G5C61_RS16340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G5C61_RS16350	COG1968	undecaprenyl-diphosphatase activity
G5C61_RS16355	COG1301	dicarboxylic acid transport
G5C61_RS16365	COG0586	Pfam SNARE associated Golgi protein
G5C61_RS16370	COG2217	Heavy metal translocating P-type atpase
G5C61_RS16375	COG0531	amino acid
G5C61_RS16390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G5C61_RS16395	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G5C61_RS16400	COG3842	ATPase activity
G5C61_RS16405	COG1175	transmembrane transport
G5C61_RS16420	COG0584	glycerophosphoryl diester phosphodiesterase
G5C61_RS16435	COG4948	Mandelate Racemase Muconate Lactonizing
G5C61_RS16480	COG3584	3D domain protein
G5C61_RS16480	COG1388	LysM domain
G5C61_RS16485	COG1876	peptidase activity
G5C61_RS16495	COG3103	Sh3 type 3 domain protein
G5C61_RS16505	COG0456	acetyltransferase
G5C61_RS16505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS16510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS16530	COG1609	Transcriptional regulator
G5C61_RS16535	COG2814	Major facilitator Superfamily
G5C61_RS16540	COG0673	inositol 2-dehydrogenase activity
G5C61_RS16565	COG1609	Transcriptional regulator
G5C61_RS16580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS16585	COG1522	sequence-specific DNA binding
G5C61_RS16605	COG2814	Major facilitator Superfamily
G5C61_RS16610	COG1309	transcriptional regulator
G5C61_RS16615	COG1187	pseudouridine synthase activity
G5C61_RS16630	COG1942	4-Oxalocrotonate Tautomerase
G5C61_RS16635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G5C61_RS16650	COG2851	Citrate transporter
G5C61_RS16665	COG0084	hydrolase, TatD family'
G5C61_RS16675	COG2962	Rard protein
G5C61_RS16685	COG0628	permease
G5C61_RS16700	COG0604	alcohol dehydrogenase
G5C61_RS16705	COG1620	l-lactate permease
G5C61_RS16715	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G5C61_RS16720	COG0840	transmembrane signaling receptor activity
G5C61_RS16725	COG0564	pseudouridine synthase activity
G5C61_RS16735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5C61_RS16740	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS16745	COG3153	acetyltransferase
G5C61_RS16745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5C61_RS16750	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
G5C61_RS16755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G5C61_RS16760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G5C61_RS16765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G5C61_RS16770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G5C61_RS16775	COG1268	BioY protein
G5C61_RS16785	COG2719	SpoVR family
G5C61_RS16795	COG1959	2 iron, 2 sulfur cluster binding
G5C61_RS16800	COG0604	alcohol dehydrogenase
G5C61_RS16810	COG1126	abc transporter atp-binding protein
G5C61_RS16815	COG0765	amino acid transport
G5C61_RS16820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS16825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G5C61_RS16830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G5C61_RS16840	COG0352	thiamine-phosphate diphosphorylase activity
G5C61_RS16845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5C61_RS16860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G5C61_RS16865	COG0351	phosphomethylpyrimidine kinase
G5C61_RS16880	COG0702	epimerase
G5C61_RS16885	COG1253	flavin adenine dinucleotide binding
G5C61_RS16900	COG3842	ATPase activity
G5C61_RS16905	COG2508	Transcriptional regulator
G5C61_RS16920	COG0189	ligase activity
G5C61_RS16925	COG0189	ligase activity
G5C61_RS16935	COG3679	Belongs to the UPF0342 family
G5C61_RS16940	COG0561	phosphatase activity
G5C61_RS16945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G5C61_RS16950	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS16955	COG1024	Enoyl-CoA hydratase
G5C61_RS16970	COG4152	abc transporter atp-binding protein
G5C61_RS16975	COG1668	transmembrane transport
G5C61_RS16980	COG3481	metal-dependent phosphohydrolase, HD sub domain
G5C61_RS16990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5C61_RS17015	COG1846	Transcriptional regulator
G5C61_RS17030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G5C61_RS17035	COG1695	Transcriptional regulator
G5C61_RS17040	COG2153	protein acetylation
G5C61_RS17045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G5C61_RS17045	COG2755	lipolytic protein G-D-S-L family
G5C61_RS17050	COG0537	adenosine 5'-monophosphoramidase activity
G5C61_RS17055	COG1131	(ABC) transporter
G5C61_RS17060	COG4473	ABC transporter
G5C61_RS17070	COG1473	amidohydrolase
G5C61_RS17075	COG0671	phosphoesterase, PA-phosphatase related
G5C61_RS17080	COG3069	C4-dicarboxylate transmembrane transporter activity
G5C61_RS17085	COG2329	Antibiotic biosynthesis monooxygenase
G5C61_RS17090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5C61_RS17095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G5C61_RS17110	COG1309	transcriptional regulator
G5C61_RS17125	COG2972	Histidine kinase
G5C61_RS17140	COG1234	tRNA 3'-trailer cleavage
G5C61_RS17145	COG0095	Lipoate-protein ligase
G5C61_RS17150	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS17155	COG1024	Enoyl-CoA hydratase
G5C61_RS17270	COG0501	Belongs to the peptidase M48B family
G5C61_RS17275	COG2224	Isocitrate lyase
G5C61_RS17285	COG0823	Involved in the tonB-independent uptake of proteins
G5C61_RS17285	COG4946	Tricorn protease homolog
G5C61_RS17285	COG1506	peptidase
G5C61_RS17290	COG0398	Pfam SNARE associated Golgi protein
G5C61_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS17300	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
G5C61_RS17305	COG1074	ATP-dependent DNA helicase activity
G5C61_RS17310	COG0420	3'-5' exonuclease activity
G5C61_RS17315	COG0419	ATPase involved in DNA repair
G5C61_RS17320	COG1403	HNH endonuclease
G5C61_RS17355	COG2311	Membrane
G5C61_RS17370	COG0367	asparagine synthase
G5C61_RS17385	COG1562	ergosterol biosynthetic process
G5C61_RS17390	COG0347	Belongs to the P(II) protein family
G5C61_RS17395	COG0004	ammonium transporteR
G5C61_RS17400	COG1874	Beta-galactosidase
G5C61_RS17400	COG0366	Alpha amylase catalytic
G5C61_RS17405	COG1609	Transcriptional regulator
G5C61_RS17410	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS17415	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G5C61_RS17420	COG4187	Peptidase family M20/M25/M40
G5C61_RS17425	COG0833	amino acid
G5C61_RS17430	COG3829	transcription factor binding
G5C61_RS17435	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS17440	COG1666	GTP binding
G5C61_RS17445	COG2996	Protein conserved in bacteria
G5C61_RS17455	COG1307	EDD domain protein, DegV family
G5C61_RS17460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS17475	COG0561	phosphatase activity
G5C61_RS17480	COG2151	metal-sulfur cluster biosynthetic enzyme
G5C61_RS17485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G5C61_RS17490	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G5C61_RS17495	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G5C61_RS17500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G5C61_RS17520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G5C61_RS17540	COG0542	response to heat
G5C61_RS17555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G5C61_RS17560	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
G5C61_RS17565	COG2084	Dehydrogenase
G5C61_RS17575	COG2267	carboxylic ester hydrolase activity
G5C61_RS17595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G5C61_RS17600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5C61_RS17605	COG5504	Zn-dependent protease
G5C61_RS17610	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS17615	COG4608	Belongs to the ABC transporter superfamily
G5C61_RS17625	COG0601	transmembrane transport
G5C61_RS17640	COG0180	Tryptophanyl-tRNA synthetase
G5C61_RS17645	COG4166	transmembrane transport
G5C61_RS17650	COG0601	transmembrane transport
G5C61_RS17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS17660	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS17665	COG4608	Belongs to the ABC transporter superfamily
G5C61_RS17670	COG0456	acetyltransferase
G5C61_RS17675	COG1113	amino acid transport
G5C61_RS17685	COG0531	amino acid
G5C61_RS17690	COG1393	Belongs to the ArsC family
G5C61_RS17695	COG0583	DNA-binding transcription factor activity
G5C61_RS17710	COG0861	Integral membrane protein TerC family
G5C61_RS17720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS17730	COG1164	Oligoendopeptidase f
G5C61_RS17745	COG2346	COG2346, Truncated hemoglobins
G5C61_RS17750	COG0741	lytic transglycosylase activity
G5C61_RS17755	COG4116	CYTH
G5C61_RS17765	COG2357	RelA SpoT domain protein
G5C61_RS17775	COG0564	pseudouridine synthase activity
G5C61_RS17780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G5C61_RS17785	COG2239	Acts as a magnesium transporter
G5C61_RS17790	COG0569	domain protein
G5C61_RS17790	COG0475	glutathione-regulated potassium exporter activity
G5C61_RS17850	COG0210	DNA helicase
G5C61_RS17860	COG2323	membrane
G5C61_RS17865	COG2153	protein acetylation
G5C61_RS17875	COG2382	esterase
G5C61_RS17885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G5C61_RS17895	COG1737	Transcriptional regulator
G5C61_RS17900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G5C61_RS17905	COG1070	Carbohydrate kinase
G5C61_RS17910	COG1953	Uracil, thiamine, allantoin
G5C61_RS17930	COG1522	sequence-specific DNA binding
G5C61_RS17940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G5C61_RS17960	COG3142	Participates in the control of copper homeostasis
G5C61_RS17965	COG1113	amino acid transport
G5C61_RS17975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS17980	COG1309	transcriptional regulator
G5C61_RS17985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS17985	COG3711	transcriptional antiterminator
G5C61_RS17990	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G5C61_RS17995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G5C61_RS18000	COG1447	Phosphotransferase system cellobiose-specific component IIA
G5C61_RS18005	COG1486	melibiose metabolic process
G5C61_RS18010	COG3275	phosphorelay sensor kinase activity
G5C61_RS18015	COG3279	Response regulator of the LytR AlgR family
G5C61_RS18025	COG1346	cytolysis
G5C61_RS18035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5C61_RS18040	COG0243	molybdopterin cofactor binding
G5C61_RS18045	COG2223	nitrite transmembrane transporter activity
G5C61_RS18050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
G5C61_RS18065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G5C61_RS18080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G5C61_RS18080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5C61_RS18090	COG3527	Alpha-acetolactate decarboxylase
G5C61_RS18095	COG0028	Belongs to the TPP enzyme family
G5C61_RS18105	COG4895	conserved protein (DUF2196)
G5C61_RS18115	COG1733	regulation of RNA biosynthetic process
G5C61_RS18120	COG2814	Major facilitator Superfamily
G5C61_RS18125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS18145	COG3052	prosthetic group binding
G5C61_RS18160	COG0784	Response regulator, receiver
G5C61_RS18165	COG4191	Histidine kinase
G5C61_RS18170	COG2066	Belongs to the glutaminase family
G5C61_RS18175	COG1115	amino acid carrier protein
G5C61_RS18180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5C61_RS18190	COG4297	protein containing double-stranded beta helix domain
G5C61_RS18195	COG0531	amino acid
G5C61_RS18205	COG1607	acyl-coa hydrolase
G5C61_RS18210	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G5C61_RS18225	COG0390	transport system, permease component
G5C61_RS18230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G5C61_RS18245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G5C61_RS18250	COG1136	(ABC) transporter
G5C61_RS18255	COG0577	efflux transmembrane transporter activity
G5C61_RS18265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G5C61_RS18270	COG1063	alcohol dehydrogenase
G5C61_RS18285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G5C61_RS18290	COG0833	amino acid
G5C61_RS18300	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G5C61_RS18305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5C61_RS18315	COG0861	Integral membrane protein TerC family
G5C61_RS18325	COG1301	dicarboxylic acid transport
G5C61_RS18330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G5C61_RS18335	COG3290	protein histidine kinase activity
G5C61_RS18375	COG1476	TRANSCRIPTIONal
G5C61_RS18385	COG1368	sulfuric ester hydrolase activity
G5C61_RS18400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS18405	COG2040	homocysteine
G5C61_RS18410	COG0179	Fumarylacetoacetate (FAA) hydrolase
G5C61_RS18425	COG2851	Citrate transporter
G5C61_RS18430	COG3290	protein histidine kinase activity
G5C61_RS18435	COG4565	transcriptional regulatory protein
G5C61_RS18440	COG3181	Tripartite tricarboxylate transporter family receptor
G5C61_RS18450	COG0583	DNA-binding transcription factor activity
G5C61_RS18455	COG3180	Ammonia monooxygenase
G5C61_RS18460	COG2226	methyltransferase
G5C61_RS18465	COG4176	ABC-type proline glycine betaine transport system permease component
G5C61_RS18470	COG4175	Glycine betaine
G5C61_RS18470	COG0517	IMP dehydrogenase activity
G5C61_RS18475	COG2113	Glycine betaine
G5C61_RS18480	COG1309	transcriptional regulator
G5C61_RS18485	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS18500	COG0531	amino acid
G5C61_RS18505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G5C61_RS18510	COG1464	Belongs to the NlpA lipoprotein family
G5C61_RS18515	COG2011	ABC-type metal ion transport system permease component
G5C61_RS18520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G5C61_RS18535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS18545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G5C61_RS18550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS18555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS18585	COG1737	Transcriptional regulator
G5C61_RS18590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS18590	COG1263	PTS System
G5C61_RS18600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G5C61_RS18605	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G5C61_RS18610	COG1116	anion transmembrane transporter activity
G5C61_RS18615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G5C61_RS18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G5C61_RS18630	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G5C61_RS18635	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
G5C61_RS18640	COG1733	regulation of RNA biosynthetic process
G5C61_RS18675	COG1511	domain protein
G5C61_RS18680	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G5C61_RS18685	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G5C61_RS18690	COG1733	regulation of RNA biosynthetic process
G5C61_RS18700	COG1132	(ABC) transporter
G5C61_RS18705	COG1132	(ABC) transporter
G5C61_RS18715	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5C61_RS18720	COG3162	membrane
G5C61_RS18730	COG1414	Transcriptional regulator
G5C61_RS18735	COG0656	L-ascorbic acid biosynthetic process
G5C61_RS18740	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G5C61_RS18745	COG1846	Transcriptional regulator
G5C61_RS18750	COG1566	PFAM secretion protein HlyD family protein
G5C61_RS18755	COG2814	Major facilitator Superfamily
G5C61_RS18760	COG0655	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS18775	COG1609	Transcriptional regulator
G5C61_RS18790	COG1129	ABC transporter
G5C61_RS18795	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5C61_RS18800	COG1879	ABC-type sugar transport system periplasmic component
G5C61_RS18805	COG3583	domain protein
G5C61_RS18805	COG3584	3D domain protein
G5C61_RS18810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G5C61_RS18815	COG1653	transport
G5C61_RS18860	COG0745	RESPONSE REGULATOR receiver
G5C61_RS18865	COG5002	protein histidine kinase activity
G5C61_RS18875	COG2267	carboxylic ester hydrolase activity
G5C61_RS18900	COG0402	S-adenosylhomocysteine deaminase activity
G5C61_RS18905	COG2252	PERMEase
G5C61_RS18915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G5C61_RS18920	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS18930	COG0710	3-dehydroquinate dehydratase activity
G5C61_RS18945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS18945	COG1263	PTS System
G5C61_RS18950	COG0366	Alpha amylase catalytic
G5C61_RS18955	COG2188	Transcriptional regulator
G5C61_RS18960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G5C61_RS18965	COG1984	allophanate hydrolase subunit 2
G5C61_RS18970	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G5C61_RS18975	COG1914	H( )-stimulated, divalent metal cation uptake system
G5C61_RS18980	COG1272	protein, Hemolysin III
G5C61_RS18995	COG0778	Nitroreductase
G5C61_RS19000	COG0628	permease
G5C61_RS19025	COG2271	Major facilitator Superfamily
G5C61_RS19030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G5C61_RS19035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5C61_RS19040	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS19055	COG0439	Biotin carboxylase
G5C61_RS19070	COG0531	amino acid
G5C61_RS19075	COG0402	S-adenosylhomocysteine deaminase activity
G5C61_RS19085	COG1131	(ABC) transporter
G5C61_RS19090	COG1278	Cold shock
G5C61_RS19095	COG2910	NAD(P)H-binding
G5C61_RS19100	COG0673	inositol 2-dehydrogenase activity
G5C61_RS19105	COG0450	alkyl hydroperoxide reductase
G5C61_RS19110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS19135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5C61_RS19220	COG1649	PFAM Uncharacterised BCR, COG1649
G5C61_RS19225	COG1737	Transcriptional regulator
G5C61_RS19245	COG1486	melibiose metabolic process
G5C61_RS19255	COG1447	Phosphotransferase system cellobiose-specific component IIA
G5C61_RS19265	COG2971	BadF BadG BcrA BcrD
G5C61_RS19270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G5C61_RS19275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS19285	COG3037	sugar-specific permease SgaT UlaA
G5C61_RS19300	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G5C61_RS19315	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS19320	COG2226	methyltransferase
G5C61_RS19325	COG0583	DNA-binding transcription factor activity
G5C61_RS19340	COG0667	Aldo Keto reductase
G5C61_RS19365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G5C61_RS19410	COG2199	diguanylate cyclase activity
G5C61_RS19410	COG2200	EAL domain
G5C61_RS19420	COG1733	regulation of RNA biosynthetic process
G5C61_RS19435	COG0385	Bile acid
G5C61_RS19445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5C61_RS19450	COG4191	Histidine kinase
G5C61_RS19455	COG0784	Response regulator, receiver
G5C61_RS19470	COG0791	NLP P60 protein
G5C61_RS19470	COG1388	LysM domain
G5C61_RS19480	COG2385	sporulation resulting in formation of a cellular spore
G5C61_RS19485	COG0656	L-ascorbic acid biosynthetic process
G5C61_RS19500	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G5C61_RS19505	COG4948	Mandelate Racemase Muconate Lactonizing
G5C61_RS19535	COG0477	Major facilitator Superfamily
G5C61_RS19540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G5C61_RS19555	COG0640	Transcriptional regulator
G5C61_RS19560	COG5658	integral membrane protein
G5C61_RS19585	COG3300	MHYT domain
G5C61_RS19585	COG5001	Diguanylate cyclase
G5C61_RS19590	COG0302	gtp cyclohydrolase
G5C61_RS19600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G5C61_RS19620	COG3064	Membrane
G5C61_RS19635	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
G5C61_RS19640	COG1396	sequence-specific DNA binding
G5C61_RS19660	COG4464	protein tyrosine phosphatase activity
G5C61_RS19665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G5C61_RS19670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5C61_RS19675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G5C61_RS19685	COG2244	polysaccharide biosynthetic process
G5C61_RS19700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G5C61_RS19720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
G5C61_RS19735	COG1091	dTDP-4-dehydrorhamnose reductase activity
G5C61_RS19740	COG3944	biosynthesis protein
G5C61_RS19745	COG0489	protein tyrosine kinase activity
G5C61_RS19755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G5C61_RS19760	COG4464	protein tyrosine phosphatase activity
G5C61_RS19775	COG0028	Belongs to the TPP enzyme family
G5C61_RS19780	COG0069	glutamate synthase activity
G5C61_RS19790	COG2084	Dehydrogenase
G5C61_RS19820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G5C61_RS19825	COG2146	nitrite reductase [NAD(P)H] activity
G5C61_RS19835	COG2116	formate transmembrane transporter activity
G5C61_RS19845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS19850	COG4975	Glucose uptake
G5C61_RS19870	COG0534	Mate efflux family protein
G5C61_RS19880	COG1316	TRANSCRIPTIONal
G5C61_RS19890	COG0598	Magnesium transport protein CorA
G5C61_RS19895	COG1404	Belongs to the peptidase S8 family
G5C61_RS19925	COG4821	SIS domain
G5C61_RS19930	COG2188	Transcriptional regulator
G5C61_RS19935	COG0363	glucosamine-6-phosphate deaminase activity
G5C61_RS19940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G5C61_RS19945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS19945	COG1263	PTS System
G5C61_RS19945	COG2190	(PTS) system
G5C61_RS19950	COG1811	Na channel or pump
G5C61_RS19985	COG1131	(ABC) transporter
G5C61_RS19990	COG1253	flavin adenine dinucleotide binding
G5C61_RS19995	COG0789	Transcriptional regulator
G5C61_RS20005	COG0346	lactoylglutathione lyase activity
G5C61_RS20010	COG2105	PFAM AIG2 family protein
G5C61_RS20010	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
G5C61_RS20055	COG0456	acetyltransferase
G5C61_RS20060	COG1473	amidohydrolase
G5C61_RS20070	COG4187	Peptidase family M20/M25/M40
G5C61_RS20085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G5C61_RS20085	COG0456	acetyltransferase
G5C61_RS20100	COG2252	PERMEase
G5C61_RS20110	COG3279	Response regulator of the LytR AlgR family
G5C61_RS20115	COG4555	ABC transporter
G5C61_RS20120	COG1668	transmembrane transport
G5C61_RS20130	COG0789	Transcriptional regulator
G5C61_RS20135	COG1846	Transcriptional regulator
G5C61_RS20140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5C61_RS20140	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5C61_RS20160	COG1785	Belongs to the alkaline phosphatase family
G5C61_RS20165	COG3279	Response regulator of the LytR AlgR family
G5C61_RS20175	COG0861	Integral membrane protein TerC family
G5C61_RS20180	COG1191	sigma factor activity
G5C61_RS20210	COG3243	poly(R)-hydroxyalkanoic acid synthase
G5C61_RS20215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5C61_RS20235	COG2186	Transcriptional regulator
G5C61_RS20240	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G5C61_RS20250	COG0247	lactate metabolic process
G5C61_RS20255	COG1139	Iron-sulfur cluster binding protein
G5C61_RS20260	COG1556	Lactate utilization protein
G5C61_RS20265	COG5002	protein histidine kinase activity
G5C61_RS20270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G5C61_RS20280	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
G5C61_RS20285	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
G5C61_RS20290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5C61_RS20295	COG0436	Aminotransferase
G5C61_RS20300	COG1850	ribulose-bisphosphate carboxylase activity
G5C61_RS20305	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
G5C61_RS20310	COG0235	Class ii aldolase
G5C61_RS20315	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
G5C61_RS20325	COG1129	ABC transporter
G5C61_RS20330	COG1172	Belongs to the binding-protein-dependent transport system permease family
G5C61_RS20355	COG1846	Transcriptional regulator
G5C61_RS20365	COG4191	Histidine kinase
G5C61_RS20375	COG0542	response to heat
G5C61_RS20390	COG0300	oxidoreductase activity
G5C61_RS20395	COG0697	spore germination
G5C61_RS20415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G5C61_RS20420	COG0720	synthase
G5C61_RS20430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G5C61_RS20435	COG0702	epimerase
G5C61_RS20445	COG4873	Protein conserved in bacteria
G5C61_RS20465	COG3773	Cell wall hydrolase
G5C61_RS20505	COG1410	methionine synthase
G5C61_RS20505	COG0646	methionine synthase
G5C61_RS20510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G5C61_RS20510	COG0646	methionine synthase
G5C61_RS20515	COG3949	Membrane
G5C61_RS20525	COG0307	riboflavin synthase, alpha
G5C61_RS20535	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G5C61_RS20545	COG3711	transcriptional antiterminator
G5C61_RS20550	COG2190	(PTS) system
G5C61_RS20550	COG1263	PTS System
G5C61_RS20550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS20565	COG1346	cytolysis
G5C61_RS20575	COG0583	DNA-binding transcription factor activity
G5C61_RS20585	COG0456	acetyltransferase
G5C61_RS20595	COG0778	Nitroreductase
G5C61_RS20600	COG0436	Aminotransferase
G5C61_RS20620	COG0835	chemotaxis
G5C61_RS20620	COG0784	Response regulator, receiver
G5C61_RS20630	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS20650	COG1408	metallophosphoesterase
G5C61_RS20655	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS20660	COG2200	EAL domain
G5C61_RS20675	COG4703	Protein of unknown function (DUF1797)
G5C61_RS20680	COG0517	IMP dehydrogenase activity
G5C61_RS20685	COG0583	DNA-binding transcription factor activity
G5C61_RS20690	COG2171	N-acyltransferase activity
G5C61_RS20695	COG1473	amidohydrolase
G5C61_RS20705	COG0668	transmembrane transport
G5C61_RS20710	COG0450	alkyl hydroperoxide reductase
G5C61_RS20715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS20720	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G5C61_RS20725	COG1132	(ABC) transporter
G5C61_RS20730	COG1132	(ABC) transporter
G5C61_RS20735	COG0569	domain protein
G5C61_RS20740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G5C61_RS20750	COG0561	phosphatase activity
G5C61_RS20775	COG0022	dehydrogenase e1 component
G5C61_RS20780	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5C61_RS20795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G5C61_RS20805	COG1982	Orn Lys Arg decarboxylase major
G5C61_RS20810	COG4476	Belongs to the UPF0223 family
G5C61_RS20815	COG4493	Belongs to the UPF0637 family
G5C61_RS20825	COG0483	inositol monophosphate 1-phosphatase activity
G5C61_RS20850	COG4896	Protein conserved in bacteria
G5C61_RS20865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G5C61_RS20870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G5C61_RS20875	COG4838	Belongs to the UPF0358 family
G5C61_RS20880	COG0772	Belongs to the SEDS family
G5C61_RS20885	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G5C61_RS20890	COG1612	heme a metabolic process
G5C61_RS20895	COG0109	protoheme IX farnesyltransferase activity
G5C61_RS20920	COG3336	cytochrome c oxidase
G5C61_RS20935	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G5C61_RS20940	COG2340	Cysteine-rich secretory protein family
G5C61_RS20950	COG2738	Putative neutral zinc metallopeptidase
G5C61_RS20955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS20960	COG1694	Mazg nucleotide pyrophosphohydrolase
G5C61_RS20965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G5C61_RS20970	COG1803	Methylglyoxal synthase
G5C61_RS20975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G5C61_RS20980	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS20985	COG0617	tRNA 3'-terminal CCA addition
G5C61_RS20990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
G5C61_RS20990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
G5C61_RS21000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G5C61_RS21005	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
G5C61_RS21010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G5C61_RS21010	COG1199	ATP-dependent helicase activity
G5C61_RS21030	COG0436	Aminotransferase
G5C61_RS21035	COG0017	Asparaginyl-tRNA synthetase
G5C61_RS21040	COG3935	DnaD domain protein
G5C61_RS21045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G5C61_RS21055	COG4499	WXG100 protein secretion system (Wss), protein YukC
G5C61_RS21055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G5C61_RS21060	COG3331	DNA recombination
G5C61_RS21105	COG5337	Spore coat protein CotH
G5C61_RS21120	COG0626	cystathionine gamma-synthase activity
G5C61_RS21125	COG0626	cystathionine gamma-synthase activity
G5C61_RS21140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5C61_RS21170	COG3706	GGDEF domain
G5C61_RS21180	COG1205	dead DEAH box helicase
G5C61_RS21180	COG1111	helicase
G5C61_RS21185	COG3359	exonuclease
G5C61_RS21195	COG4474	Belongs to the UPF0398 family
G5C61_RS21200	COG3599	regulation of cell shape
G5C61_RS21230	COG2197	response regulator
G5C61_RS21235	COG0366	Alpha amylase catalytic
G5C61_RS21240	COG0116	Belongs to the methyltransferase superfamily
G5C61_RS21255	COG1175	transmembrane transport
G5C61_RS21265	COG3842	ATPase activity
G5C61_RS21275	COG1199	ATP-dependent helicase activity
G5C61_RS21280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G5C61_RS21285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G5C61_RS21290	COG2233	PERMEase
G5C61_RS21295	COG0583	DNA-binding transcription factor activity
G5C61_RS21300	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS21310	COG3424	synthase
G5C61_RS21315	COG1755	Isoprenylcysteine carboxyl methyltransferase
G5C61_RS21320	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
G5C61_RS21325	COG3541	Predicted nucleotidyltransferase
G5C61_RS21350	COG0328	RNA-DNA hybrid ribonuclease activity
G5C61_RS21355	COG0328	RNA-DNA hybrid ribonuclease activity
G5C61_RS21380	COG2814	Major facilitator Superfamily
G5C61_RS21390	COG2233	PERMEase
G5C61_RS21395	COG2362	D-Aminopeptidase
G5C61_RS21400	COG0601	transmembrane transport
G5C61_RS21405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS21410	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS21415	COG4166	transmembrane transport
G5C61_RS21420	COG1619	proteins homologs of microcin C7 resistance protein MccF
G5C61_RS21425	COG0791	NLP P60 protein
G5C61_RS21430	COG4608	Belongs to the ABC transporter superfamily
G5C61_RS21465	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
G5C61_RS21470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS21475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS21480	COG1120	ATPase activity
G5C61_RS21505	COG2197	response regulator
G5C61_RS21510	COG4585	Histidine kinase
G5C61_RS21515	COG3239	Fatty acid desaturase
G5C61_RS21520	COG2205	protein histidine kinase activity
G5C61_RS21530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS21545	COG0791	NLP P60 protein
G5C61_RS21545	COG1388	LysM domain
G5C61_RS21550	COG1819	glycosyl
G5C61_RS21555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G5C61_RS21565	COG2814	Major facilitator Superfamily
G5C61_RS21580	COG3964	amidohydrolase
G5C61_RS21600	COG2188	Transcriptional regulator
G5C61_RS21610	COG0434	BtpA family
G5C61_RS21620	COG1785	Belongs to the alkaline phosphatase family
G5C61_RS21625	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G5C61_RS21630	COG1404	Belongs to the peptidase S8 family
G5C61_RS21640	COG1846	Transcriptional regulator
G5C61_RS21645	COG1566	PFAM secretion protein HlyD family protein
G5C61_RS21650	COG2814	Major facilitator Superfamily
G5C61_RS21675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS21680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G5C61_RS21685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5C61_RS21690	COG1120	ATPase activity
G5C61_RS21695	COG0492	ferredoxin-NADP+ reductase activity
G5C61_RS21705	COG2814	Major facilitator Superfamily
G5C61_RS21720	COG4585	Histidine kinase
G5C61_RS21725	COG2197	response regulator
G5C61_RS21730	COG2409	Drug exporters of the RND superfamily
G5C61_RS21745	COG0583	DNA-binding transcription factor activity
G5C61_RS21750	COG0488	(ABC) transporter
G5C61_RS21765	COG3153	acetyltransferase
G5C61_RS21765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G5C61_RS21785	COG0583	DNA-binding transcription factor activity
G5C61_RS21795	COG2814	Major facilitator Superfamily
G5C61_RS21800	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS21820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5C61_RS21825	COG1733	regulation of RNA biosynthetic process
G5C61_RS21830	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
G5C61_RS21840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5C61_RS21845	COG4638	Rieske (2fe-2S)
G5C61_RS21850	COG4175	Glycine betaine
G5C61_RS21850	COG3448	diguanylate cyclase activity
G5C61_RS21865	COG0469	pyruvate kinase activity
G5C61_RS21870	COG2205	protein histidine kinase activity
G5C61_RS21870	COG0784	Response regulator, receiver
G5C61_RS21875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G5C61_RS21880	COG2208	phosphoserine phosphatase activity
G5C61_RS21890	COG0531	amino acid
G5C61_RS21900	COG1011	Hydrolase
G5C61_RS21905	COG0405	Gamma-glutamyltransferase
G5C61_RS21910	COG1621	beta-fructofuranosidase activity
G5C61_RS21915	COG1621	beta-fructofuranosidase activity
G5C61_RS21920	COG2193	ferroxidase activity
G5C61_RS21925	COG0477	Major facilitator Superfamily
G5C61_RS21930	COG0156	8-amino-7-oxononanoate synthase activity
G5C61_RS21935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G5C61_RS21945	COG2814	Major facilitator Superfamily
G5C61_RS21960	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS21965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS21975	COG1280	lysine exporter protein (LysE YggA)
G5C61_RS21980	COG1113	amino acid transport
G5C61_RS21995	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
G5C61_RS22025	COG1113	amino acid transport
G5C61_RS22045	COG1609	Transcriptional regulator
G5C61_RS22050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G5C61_RS22055	COG1621	beta-fructofuranosidase activity
G5C61_RS22060	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G5C61_RS22060	COG3933	PFAM sigma-54 factor interaction domain-containing protein
G5C61_RS22065	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS22070	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS22075	COG3715	PTS system
G5C61_RS22080	COG3716	PTS system mannose fructose sorbose family IID component
G5C61_RS22085	COG1621	beta-fructofuranosidase activity
G5C61_RS22090	COG0765	amino acid transport
G5C61_RS22095	COG0765	amino acid transport
G5C61_RS22100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS22105	COG1464	Belongs to the NlpA lipoprotein family
G5C61_RS22110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G5C61_RS22115	COG2011	ABC-type metal ion transport system permease component
G5C61_RS22135	COG1464	Belongs to the NlpA lipoprotein family
G5C61_RS22140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G5C61_RS22145	COG2011	ABC-type metal ion transport system permease component
G5C61_RS22150	COG1464	Belongs to the NlpA lipoprotein family
G5C61_RS22155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS22160	COG0024	Methionine aminopeptidase
G5C61_RS22170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G5C61_RS22180	COG0656	L-ascorbic acid biosynthetic process
G5C61_RS22185	COG2986	histidine ammonia-lyase
G5C61_RS22195	COG1228	amidohydrolase
G5C61_RS22200	COG0010	Belongs to the arginase family
G5C61_RS22205	COG1846	Transcriptional regulator
G5C61_RS22220	COG0473	3-isopropylmalate dehydrogenase activity
G5C61_RS22225	COG1288	antiporter activity
G5C61_RS22230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G5C61_RS22255	COG0789	Transcriptional regulator
G5C61_RS22280	COG2364	Membrane
G5C61_RS22285	COG1846	Transcriptional regulator
G5C61_RS22290	COG0456	acetyltransferase
G5C61_RS22330	COG0574	Belongs to the PEP-utilizing enzyme family
G5C61_RS22330	COG3848	Pyruvate phosphate dikinase
G5C61_RS22335	COG1309	transcriptional regulator
G5C61_RS22340	COG2814	Major facilitator Superfamily
G5C61_RS22345	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G5C61_RS22350	COG3958	Transketolase
G5C61_RS22355	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS22360	COG2186	Transcriptional regulator
G5C61_RS22370	COG0205	6-phosphofructokinase activity
G5C61_RS22380	COG0698	ribose 5-phosphate isomerase
G5C61_RS22385	COG0494	nUDIX hydrolase
G5C61_RS22405	COG2318	DinB family
G5C61_RS22435	COG0583	DNA-binding transcription factor activity
G5C61_RS22455	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS22475	COG0586	Pfam SNARE associated Golgi protein
G5C61_RS22490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS22500	COG0697	spore germination
G5C61_RS22535	COG1609	Transcriptional regulator
G5C61_RS22540	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G5C61_RS22545	COG2610	gluconate transmembrane transporter activity
G5C61_RS22550	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS22555	COG1250	3-hydroxyacyl-CoA dehydrogenase
G5C61_RS22560	COG0697	spore germination
G5C61_RS22565	COG0583	DNA-binding transcription factor activity
G5C61_RS22580	COG0861	Integral membrane protein TerC family
G5C61_RS22590	COG5577	PFAM Coat F domain
G5C61_RS22600	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS22610	COG1522	sequence-specific DNA binding
G5C61_RS22615	COG3813	Protein conserved in bacteria
G5C61_RS22640	COG2076	Multidrug Resistance protein
G5C61_RS22660	COG1278	Cold shock
G5C61_RS22670	COG0513	Belongs to the DEAD box helicase family
G5C61_RS22675	COG1278	Cold shock
G5C61_RS22685	COG0028	Belongs to the TPP enzyme family
G5C61_RS22745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5C61_RS22750	COG2076	Multidrug Resistance protein
G5C61_RS22755	COG0517	IMP dehydrogenase activity
G5C61_RS22790	COG0011	TIGRFAM Protein of
G5C61_RS22795	COG0517	IMP dehydrogenase activity
G5C61_RS22825	COG2807	transmembrane transport
G5C61_RS22855	COG2172	sigma factor antagonist activity
G5C61_RS22860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS22865	COG0477	Major facilitator Superfamily
G5C61_RS22875	COG1376	ErfK ybiS ycfS ynhG family protein
G5C61_RS22880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G5C61_RS22900	COG2226	methyltransferase
G5C61_RS22905	COG0789	Transcriptional regulator
G5C61_RS22910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G5C61_RS22935	COG0747	negative chemotaxis
G5C61_RS22940	COG0601	transmembrane transport
G5C61_RS22945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G5C61_RS22950	COG0444	Belongs to the ABC transporter superfamily
G5C61_RS22955	COG4608	Belongs to the ABC transporter superfamily
G5C61_RS22960	COG0534	Mate efflux family protein
G5C61_RS22965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS22985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G5C61_RS22995	COG2372	response to copper ion
G5C61_RS22995	COG1276	copper resistance
G5C61_RS23000	COG4549	nuclear export factor GLE1
G5C61_RS23005	COG3689	TIGRFAM TIGR03943 family protein
G5C61_RS23010	COG0701	Predicted permease
G5C61_RS23020	COG0701	Predicted permease
G5C61_RS23025	COG0803	Belongs to the bacterial solute-binding protein 9 family
G5C61_RS23030	COG1121	(ABC) transporter
G5C61_RS23035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G5C61_RS23040	COG1469	GTP cyclohydrolase I activity
G5C61_RS23065	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G5C61_RS23090	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS23095	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS23100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G5C61_RS23105	COG3328	transposase activity
G5C61_RS23110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS23115	COG2808	Putative FMN-binding domain
G5C61_RS23135	COG2814	Major facilitator Superfamily
G5C61_RS23145	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS23160	COG0667	Aldo Keto reductase
G5C61_RS23170	COG2249	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS23175	COG1309	transcriptional regulator
G5C61_RS23190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G5C61_RS23195	COG2814	Major facilitator Superfamily
G5C61_RS23200	COG0656	L-ascorbic acid biosynthetic process
G5C61_RS23210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS23220	COG2271	Major facilitator Superfamily
G5C61_RS23225	COG0824	Thioesterase
G5C61_RS23250	COG1819	glycosyl
G5C61_RS23255	COG1309	transcriptional regulator
G5C61_RS23280	COG3773	Cell wall hydrolase
G5C61_RS23290	COG0477	Major facilitator Superfamily
G5C61_RS23310	COG1914	H( )-stimulated, divalent metal cation uptake system
G5C61_RS23355	COG2217	Heavy metal translocating P-type atpase
G5C61_RS23375	COG5553	Cysteine dioxygenase type I
G5C61_RS23380	COG0697	spore germination
G5C61_RS23385	COG5582	Belongs to the UPF0302 family
G5C61_RS23390	COG1733	regulation of RNA biosynthetic process
G5C61_RS23395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G5C61_RS23405	COG2207	Transcriptional regulator
G5C61_RS23415	COG2376	Dihydroxyacetone kinase
G5C61_RS23425	COG1027	Aspartate ammonia-lyase
G5C61_RS23430	COG1994	Peptidase M50
G5C61_RS23435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G5C61_RS23440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5C61_RS23470	COG1278	Cold shock
G5C61_RS23490	COG0772	Belongs to the SEDS family
G5C61_RS23505	COG5577	PFAM Coat F domain
G5C61_RS23515	COG1063	alcohol dehydrogenase
G5C61_RS23520	COG5577	PFAM Coat F domain
G5C61_RS23535	COG2205	protein histidine kinase activity
G5C61_RS23535	COG0784	Response regulator, receiver
G5C61_RS23545	COG1609	Transcriptional regulator
G5C61_RS23555	COG0673	inositol 2-dehydrogenase activity
G5C61_RS23560	COG0673	inositol 2-dehydrogenase activity
G5C61_RS23565	COG1082	Xylose isomerase domain protein TIM barrel
G5C61_RS23570	COG2814	Major facilitator Superfamily
G5C61_RS23590	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS23650	COG2249	NAD(P)H dehydrogenase (quinone) activity
G5C61_RS23695	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS23725	COG0300	oxidoreductase activity
G5C61_RS23730	COG1063	alcohol dehydrogenase
G5C61_RS23735	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
G5C61_RS23745	COG2814	Major facilitator Superfamily
G5C61_RS23750	COG1609	Transcriptional regulator
G5C61_RS23760	COG1175	transmembrane transport
G5C61_RS23765	COG0395	ABC-type sugar transport system, permease component
G5C61_RS23780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS23785	COG0110	maltose O-acetyltransferase activity
G5C61_RS23800	COG1309	transcriptional regulator
G5C61_RS23815	COG0300	oxidoreductase activity
G5C61_RS23820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G5C61_RS23825	COG1114	Component of the transport system for branched-chain amino acids
G5C61_RS23830	COG0673	inositol 2-dehydrogenase activity
G5C61_RS23835	COG2814	Major facilitator Superfamily
G5C61_RS23840	COG1609	Transcriptional regulator
G5C61_RS23850	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G5C61_RS23865	COG0667	Aldo Keto reductase
G5C61_RS23870	COG2207	Transcriptional regulator
G5C61_RS23875	COG4282	regulation of fungal-type cell wall biogenesis
G5C61_RS23885	COG3848	Pyruvate phosphate dikinase
G5C61_RS23885	COG0574	Belongs to the PEP-utilizing enzyme family
G5C61_RS23900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G5C61_RS23915	COG3852	Histidine kinase
G5C61_RS23920	COG2204	response regulator
G5C61_RS23930	COG0477	Major facilitator Superfamily
G5C61_RS23955	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS23990	COG0517	IMP dehydrogenase activity
G5C61_RS24005	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G5C61_RS24010	COG1063	alcohol dehydrogenase
G5C61_RS24015	COG0800	Aldolase
G5C61_RS24020	COG1312	Catalyzes the dehydration of D-mannonate
G5C61_RS24025	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS24030	COG1609	Transcriptional regulator
G5C61_RS24035	COG2271	Major facilitator Superfamily
G5C61_RS24040	COG3708	Transcriptional regulator
G5C61_RS24040	COG2207	Transcriptional regulator
G5C61_RS24045	COG2721	sulfolactate sulfo-lyase activity
G5C61_RS24050	COG1063	alcohol dehydrogenase
G5C61_RS24055	COG0246	Mannitol dehydrogenase
G5C61_RS24065	COG1309	transcriptional regulator
G5C61_RS24080	COG1070	Carbohydrate kinase
G5C61_RS24085	COG2814	Major facilitator Superfamily
G5C61_RS24085	COG0477	Major facilitator Superfamily
G5C61_RS24090	COG3290	protein histidine kinase activity
G5C61_RS24090	COG3829	transcription factor binding
G5C61_RS24095	COG2851	Citrate transporter
G5C61_RS24120	COG0589	response to stress
G5C61_RS24125	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS24130	COG1612	heme a metabolic process
G5C61_RS24135	COG2072	flavoprotein involved in K transport
G5C61_RS24145	COG1141	Ferredoxin
G5C61_RS24150	COG2252	PERMEase
G5C61_RS24160	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G5C61_RS24165	COG0022	dehydrogenase e1 component
G5C61_RS24170	COG0508	dehydrogenase complex catalyzes the overall conversion of
G5C61_RS24175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G5C61_RS24180	COG3284	Transcriptional regulator
G5C61_RS24185	COG1063	alcohol dehydrogenase
G5C61_RS24195	COG1846	Transcriptional regulator
G5C61_RS24210	COG2721	sulfolactate sulfo-lyase activity
G5C61_RS24220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G5C61_RS24225	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS24230	COG2271	Major facilitator Superfamily
G5C61_RS24235	COG4948	Mandelate Racemase Muconate Lactonizing
G5C61_RS24240	COG2186	Transcriptional regulator
G5C61_RS24260	COG0628	permease
G5C61_RS24265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G5C61_RS24280	COG2211	Major facilitator Superfamily
G5C61_RS24295	COG0589	response to stress
G5C61_RS24300	COG5002	protein histidine kinase activity
G5C61_RS24310	COG1937	Protein conserved in bacteria
G5C61_RS24315	COG2608	mercury ion transmembrane transporter activity
G5C61_RS24320	COG2217	Heavy metal translocating P-type atpase
G5C61_RS24330	COG1388	LysM domain
G5C61_RS24335	COG2271	Major facilitator Superfamily
G5C61_RS24365	COG0640	Transcriptional regulator
G5C61_RS24370	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G5C61_RS24385	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G5C61_RS24390	COG2323	membrane
G5C61_RS24405	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G5C61_RS24410	COG1802	Transcriptional regulator
G5C61_RS24415	COG0473	3-isopropylmalate dehydrogenase activity
G5C61_RS24420	COG2814	Major facilitator Superfamily
G5C61_RS24425	COG1733	regulation of RNA biosynthetic process
G5C61_RS24430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G5C61_RS24430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G5C61_RS24435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5C61_RS24435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G5C61_RS24460	COG2264	protein methyltransferase activity
G5C61_RS24470	COG5566	PFAM Mor transcription activator
G5C61_RS24485	COG0561	phosphatase activity
G5C61_RS24490	COG1876	peptidase activity
G5C61_RS24535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G5C61_RS24550	COG0386	Belongs to the glutathione peroxidase family
G5C61_RS24555	COG1418	mRNA catabolic process
G5C61_RS24560	COG0488	(ABC) transporter
G5C61_RS24565	COG1413	lyase activity
G5C61_RS24570	COG0726	polysaccharide deacetylase
G5C61_RS24580	COG2136	Putative SAM-dependent methyltransferase
G5C61_RS24580	COG2521	methyltransferase
G5C61_RS24590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G5C61_RS24595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5C61_RS24605	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
G5C61_RS24615	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
G5C61_RS24620	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G5C61_RS24625	COG0406	alpha-ribazole phosphatase activity
G5C61_RS24635	COG2096	Adenosyltransferase
G5C61_RS24640	COG2962	Rard protein
G5C61_RS24655	COG0523	cobalamin synthesis protein
G5C61_RS24660	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G5C61_RS24665	COG0322	excinuclease ABC activity
G5C61_RS24675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G5C61_RS24680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G5C61_RS24685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G5C61_RS24690	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G5C61_RS24695	COG3011	Protein conserved in bacteria
G5C61_RS24715	COG2002	toxin-antitoxin pair type II binding
G5C61_RS24720	COG0534	Mate efflux family protein
G5C61_RS24725	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS24750	COG1368	sulfuric ester hydrolase activity
G5C61_RS24760	COG3853	Toxic anion resistance protein (TelA)
G5C61_RS24795	COG5002	protein histidine kinase activity
G5C61_RS24805	COG1823	symporter activity
G5C61_RS24810	COG1523	belongs to the glycosyl hydrolase 13 family
G5C61_RS24815	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS24820	COG2124	cytochrome p450
G5C61_RS24825	COG2112	serine threonine protein kinase
G5C61_RS24840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G5C61_RS24845	COG1360	Flagellar Motor Protein
G5C61_RS24860	COG3361	conserved protein (COG2071)
G5C61_RS24865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G5C61_RS24870	COG1757	Na H antiporter
G5C61_RS24880	COG0833	amino acid
G5C61_RS24885	COG3594	Acyltransferase
G5C61_RS24890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G5C61_RS24900	COG0745	RESPONSE REGULATOR receiver
G5C61_RS24905	COG5002	protein histidine kinase activity
G5C61_RS24910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G5C61_RS24915	COG3104	oligopeptide transport
G5C61_RS24925	COG0281	malic enzyme
G5C61_RS24930	COG3493	citrate carrier protein
G5C61_RS24935	COG0561	phosphatase activity
G5C61_RS24940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS24950	COG0456	acetyltransferase
G5C61_RS24955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G5C61_RS24960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G5C61_RS24965	COG0765	amino acid transport
G5C61_RS24970	COG0765	amino acid transport
G5C61_RS24975	COG1126	abc transporter atp-binding protein
G5C61_RS24980	COG0196	riboflavin kinase activity
G5C61_RS24985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS24995	COG0860	N-Acetylmuramoyl-L-alanine amidase
G5C61_RS25035	COG1611	Belongs to the LOG family
G5C61_RS25040	COG0281	malic enzyme
G5C61_RS25045	COG3402	PFAM membrane-flanked domain
G5C61_RS25050	COG3428	Bacterial PH domain
G5C61_RS25065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS25070	COG0109	protoheme IX farnesyltransferase activity
G5C61_RS25075	COG4195	phage-related replication protein
G5C61_RS25090	COG0789	Transcriptional regulator
G5C61_RS25125	COG0583	DNA-binding transcription factor activity
G5C61_RS25130	COG0067	glutamate synthase
G5C61_RS25130	COG0070	glutamate synthase
G5C61_RS25130	COG0069	glutamate synthase activity
G5C61_RS25135	COG0493	'glutamate synthase
G5C61_RS25155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G5C61_RS25170	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS25180	COG1846	Transcriptional regulator
G5C61_RS25185	COG1380	Effector of murein hydrolase LrgA
G5C61_RS25190	COG1346	cytolysis
G5C61_RS25195	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS25210	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G5C61_RS25215	COG0463	Glycosyl transferase, family 2
G5C61_RS25220	COG2246	polysaccharide biosynthetic process
G5C61_RS25225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G5C61_RS25230	COG0745	RESPONSE REGULATOR receiver
G5C61_RS25240	COG5583	Uncharacterized small protein (DUF2292)
G5C61_RS25255	COG0745	RESPONSE REGULATOR receiver
G5C61_RS25280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G5C61_RS25295	COG1349	DNA-binding transcription factor activity
G5C61_RS25300	COG1105	Belongs to the carbohydrate kinase PfkB family
G5C61_RS25305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G5C61_RS25305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G5C61_RS25305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G5C61_RS25310	COG0527	aspartate kinase activity
G5C61_RS25320	COG2032	superoxide dismutase activity
G5C61_RS25335	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS25340	COG0640	Transcriptional regulator
G5C61_RS25345	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS25350	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G5C61_RS25365	COG0733	neurotransmitter:sodium symporter activity
G5C61_RS25370	COG3773	Cell wall hydrolase
G5C61_RS25390	COG0673	inositol 2-dehydrogenase activity
G5C61_RS25395	COG1082	Xylose isomerase domain protein TIM barrel
G5C61_RS25400	COG2094	Belongs to the DNA glycosylase MPG family
G5C61_RS25405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G5C61_RS25415	COG0454	-acetyltransferase
G5C61_RS25425	COG2814	Major facilitator Superfamily
G5C61_RS25440	COG3871	stress protein (general stress protein 26)
G5C61_RS25465	COG1595	DNA-templated transcription, initiation
G5C61_RS25470	COG4873	Protein conserved in bacteria
G5C61_RS25475	COG0714	Associated with various cellular activities
G5C61_RS25480	COG4548	von Willebrand factor, type A
G5C61_RS25485	COG0697	spore germination
G5C61_RS25495	COG2207	Transcriptional regulator
G5C61_RS25500	COG1994	Peptidase M50
G5C61_RS25505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS25510	COG1119	ATPase activity
G5C61_RS25525	COG1657	PFAM Prenyltransferase squalene oxidase
G5C61_RS25535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G5C61_RS25535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G5C61_RS25545	COG0384	phenazine biosynthesis protein PhzF
G5C61_RS25560	COG1378	Sugar-specific transcriptional regulator TrmB
G5C61_RS25565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G5C61_RS25570	COG4221	oxidoreductase activity
G5C61_RS25595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS25600	COG1279	arginine transmembrane transporter activity
G5C61_RS25635	COG3420	alginic acid biosynthetic process
G5C61_RS25635	COG5434	Belongs to the glycosyl hydrolase 28 family
G5C61_RS25645	COG0489	protein tyrosine kinase activity
G5C61_RS25655	COG1086	Polysaccharide biosynthesis protein
G5C61_RS25660	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS25665	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS25670	COG1215	transferase activity, transferring glycosyl groups
G5C61_RS25680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G5C61_RS25690	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G5C61_RS25695	COG0110	maltose O-acetyltransferase activity
G5C61_RS25700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G5C61_RS25705	COG1396	sequence-specific DNA binding
G5C61_RS25720	COG1216	Glycosyl transferase, family 2
G5C61_RS25720	COG1442	glycosyl transferase family 8
G5C61_RS25725	COG0438	transferase activity, transferring glycosyl groups
G5C61_RS25750	COG1216	Glycosyl transferase, family 2
G5C61_RS25750	COG1442	glycosyl transferase family 8
G5C61_RS25790	COG1132	(ABC) transporter
G5C61_RS25815	COG1132	(ABC) transporter
G5C61_RS25825	COG1408	metallophosphoesterase
G5C61_RS25840	COG0494	nUDIX hydrolase
G5C61_RS25845	COG1335	isochorismatase
G5C61_RS25850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G5C61_RS25855	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G5C61_RS25860	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G5C61_RS25865	COG1098	S1 RNA binding domain
G5C61_RS25870	COG1404	Belongs to the peptidase S8 family
G5C61_RS25875	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS25880	COG1254	Belongs to the acylphosphatase family
G5C61_RS25885	COG2223	nitrite transmembrane transporter activity
G5C61_RS25890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G5C61_RS25900	COG0662	Cupin 2, conserved barrel domain protein
G5C61_RS25900	COG2207	Transcriptional regulator
G5C61_RS25905	COG0697	spore germination
G5C61_RS25910	COG0488	(ABC) transporter
G5C61_RS25915	COG0697	spore germination
G5C61_RS25920	COG0531	amino acid
G5C61_RS25935	COG1131	(ABC) transporter
G5C61_RS25940	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
G5C61_RS25945	COG1757	Na H antiporter
G5C61_RS25950	COG1609	Transcriptional regulator
G5C61_RS25960	COG1533	DNA photolyase activity
G5C61_RS25980	COG0551	DNA topoisomerase type I activity
G5C61_RS25980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G5C61_RS25990	COG0446	pyridine nucleotide-disulphide oxidoreductase
G5C61_RS26010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G5C61_RS26030	COG1757	Na H antiporter
G5C61_RS26050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G5C61_RS26060	COG2720	vancomycin resistance protein
G5C61_RS26100	COG0514	ATP-dependent DNA helicase (RecQ)
G5C61_RS26115	COG1012	belongs to the aldehyde dehydrogenase family
G5C61_RS26130	COG1575	Belongs to the MenA family. Type 1 subfamily
G5C61_RS26150	COG2814	Major facilitator Superfamily
G5C61_RS26155	COG0583	DNA-binding transcription factor activity
G5C61_RS26160	COG1725	Transcriptional regulator
G5C61_RS26165	COG1131	(ABC) transporter
G5C61_RS26175	COG1595	DNA-templated transcription, initiation
G5C61_RS26190	COG1764	response to oxidative stress
G5C61_RS26195	COG1846	Transcriptional regulator
G5C61_RS26210	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
G5C61_RS26220	COG3584	3D domain protein
G5C61_RS26220	COG1388	LysM domain
G5C61_RS26240	COG5002	protein histidine kinase activity
G5C61_RS26245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G5C61_RS26250	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G5C61_RS26255	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G5C61_RS26270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5C61_RS26285	COG2409	Drug exporters of the RND superfamily
G5C61_RS26290	COG1834	amidinotransferase
G5C61_RS26300	COG1295	ribonuclease BN
G5C61_RS26400	COG0110	maltose O-acetyltransferase activity
G5C61_RS26405	COG0346	lactoylglutathione lyase activity
G5C61_RS26415	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS26425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G5C61_RS26435	COG2176	DNA-directed DNA polymerase activity
G5C61_RS26450	COG0114	fumarate hydratase activity
G5C61_RS26460	COG3757	hydrolase, family 25
G5C61_RS26460	COG3409	Peptidoglycan-binding domain 1 protein
G5C61_RS26470	COG5002	protein histidine kinase activity
G5C61_RS26510	COG0778	Nitroreductase
G5C61_RS26520	COG0300	oxidoreductase activity
G5C61_RS26525	COG3290	protein histidine kinase activity
G5C61_RS26530	COG4565	transcriptional regulatory protein
G5C61_RS26535	COG2851	Citrate transporter
G5C61_RS26545	COG2610	gluconate transmembrane transporter activity
G5C61_RS26550	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS26555	COG2195	Cleaves the N-terminal amino acid of tripeptides
G5C61_RS26580	COG4122	O-methyltransferase activity
G5C61_RS26585	COG0583	DNA-binding transcription factor activity
G5C61_RS26595	COG1301	dicarboxylic acid transport
G5C61_RS26600	COG0019	diaminopimelate decarboxylase activity
G5C61_RS26610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G5C61_RS26620	COG4191	Histidine kinase
G5C61_RS26635	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS26640	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS26655	COG1024	Enoyl-CoA hydratase
G5C61_RS26670	COG2045	Belongs to the ComB family
G5C61_RS26675	COG1960	acyl-CoA dehydrogenase activity
G5C61_RS26680	COG1028	Short-chain dehydrogenase reductase Sdr
G5C61_RS26685	COG1024	Enoyl-CoA hydratase
G5C61_RS26700	COG1141	Ferredoxin
G5C61_RS26710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G5C61_RS26715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G5C61_RS26720	COG0183	Belongs to the thiolase family
G5C61_RS26725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G5C61_RS26750	COG1509	lysine 2,3-aminomutase activity
G5C61_RS26760	COG0833	amino acid
G5C61_RS26770	COG0456	acetyltransferase
G5C61_RS26775	COG1979	alcohol dehydrogenase
G5C61_RS26780	COG0738	Major facilitator superfamily
G5C61_RS26800	COG1181	Belongs to the D-alanine--D-alanine ligase family
G5C61_RS26820	COG3977	Valine--pyruvate aminotransferase
G5C61_RS26830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G5C61_RS26835	COG3773	Cell wall hydrolase
G5C61_RS26840	COG3119	arylsulfatase activity
G5C61_RS26845	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G5C61_RS26855	COG0531	amino acid
G5C61_RS26860	COG2814	Major facilitator Superfamily
G5C61_RS26865	COG1846	Transcriptional regulator
G5C61_RS26870	COG1033	growth of symbiont in host cell
G5C61_RS26870	COG2409	Drug exporters of the RND superfamily
G5C61_RS26885	COG2222	sugar isomerase
G5C61_RS26890	COG1653	transport
G5C61_RS26895	COG1175	transmembrane transport
G5C61_RS26900	COG0395	ABC-type sugar transport system, permease component
G5C61_RS26905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G5C61_RS26910	COG2188	Transcriptional regulator
G5C61_RS26915	COG2202	Pas domain
G5C61_RS26915	COG1366	Belongs to the anti-sigma-factor antagonist family
G5C61_RS26920	COG3832	glyoxalase III activity
G5C61_RS26925	COG0640	Transcriptional regulator
G5C61_RS26935	COG2267	carboxylic ester hydrolase activity
G5C61_RS26945	COG3386	PFAM SMP-30 Gluconolaconase
G5C61_RS26955	COG2368	4-hydroxyphenylacetate
G5C61_RS26960	COG3739	integral membrane protein
G5C61_RS26970	COG0326	Molecular chaperone. Has ATPase activity
G5C61_RS26975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G5C61_RS27005	COG3757	hydrolase, family 25
G5C61_RS27005	COG3409	Peptidoglycan-binding domain 1 protein
G5C61_RS27015	COG0697	spore germination
G5C61_RS27020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G5C61_RS27035	COG4572	Cation transport regulator
G5C61_RS27040	COG2015	COG2015, Alkyl sulfatase and related hydrolases
G5C61_RS27050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G5C61_RS27135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G5C61_RS27140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G5C61_RS27150	COG0494	nUDIX hydrolase
G5C61_RS27155	COG0702	epimerase
G5C61_RS27160	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS27165	COG1846	Transcriptional regulator
G5C61_RS27170	COG2720	vancomycin resistance protein
G5C61_RS27175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G5C61_RS27200	COG0076	glutamate decarboxylase activity
G5C61_RS27230	COG5609	conserved protein (DUF2294)
G5C61_RS27245	COG2271	Major facilitator Superfamily
G5C61_RS27250	COG0277	FAD linked oxidase domain protein
G5C61_RS27260	COG0840	transmembrane signaling receptor activity
G5C61_RS27270	COG0622	Phosphoesterase
G5C61_RS27280	COG1408	metallophosphoesterase
G5C61_RS27285	COG3663	DNA glycosylase
G5C61_RS27290	COG3883	PFAM NLP P60 protein
G5C61_RS27290	COG0791	NLP P60 protein
G5C61_RS27295	COG1587	Uroporphyrinogen-III synthase
G5C61_RS27300	COG1414	Transcriptional regulator
G5C61_RS27305	COG0439	Biotin carboxylase
G5C61_RS27310	COG0511	ligase activity, forming carbon-carbon bonds
G5C61_RS27315	COG1984	allophanate hydrolase subunit 2
G5C61_RS27320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G5C61_RS27325	COG4336	lyase activity
G5C61_RS27330	COG1914	H( )-stimulated, divalent metal cation uptake system
G5C61_RS27335	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G5C61_RS27385	COG0318	PFAM AMP-dependent synthetase and ligase
G5C61_RS27390	COG1268	BioY protein
G5C61_RS27395	COG0183	Belongs to the thiolase family
G5C61_RS27405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G5C61_RS27415	COG0431	NADPH-dependent FMN reductase
G5C61_RS27420	COG2197	response regulator
G5C61_RS27425	COG2203	Gaf domain
G5C61_RS27425	COG4585	Histidine kinase
G5C61_RS27445	COG0697	spore germination
G5C61_RS27450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G5C61_RS27465	COG0346	lactoylglutathione lyase activity
G5C61_RS27470	COG0738	Major facilitator superfamily
G5C61_RS27475	COG0561	phosphatase activity
G5C61_RS27480	COG1486	melibiose metabolic process
G5C61_RS27490	COG3711	transcriptional antiterminator
G5C61_RS27495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G5C61_RS27495	COG1263	PTS System
G5C61_RS27495	COG2190	(PTS) system
G5C61_RS27500	COG2723	6-phospho-beta-galactosidase activity
G5C61_RS27510	COG0406	alpha-ribazole phosphatase activity
G5C61_RS27515	COG2223	nitrite transmembrane transporter activity
G5C61_RS27560	COG0662	Cupin 2, conserved barrel domain protein
G5C61_RS27620	COG1714	RDD family
G5C61_RS27640	COG1819	glycosyl
G5C61_RS27655	COG1994	Peptidase M50
G5C61_RS27660	COG2135	peptidase activity
G5C61_RS27670	COG0024	Methionine aminopeptidase
G5C61_RS27680	COG0517	IMP dehydrogenase activity
G5C61_RS27685	COG0011	TIGRFAM Protein of
G5C61_RS27695	COG0589	response to stress
G5C61_RS27710	COG1136	(ABC) transporter
G5C61_RS27720	COG5002	protein histidine kinase activity
G5C61_RS27730	COG2002	toxin-antitoxin pair type II binding
G5C61_RS27755	COG2002	toxin-antitoxin pair type II binding
G5C61_RS27765	COG2318	DinB family
G5C61_RS27775	COG1694	Mazg nucleotide pyrophosphohydrolase
G5C61_RS27780	COG1757	Na H antiporter
G5C61_RS27810	COG3773	Cell wall hydrolase
G5C61_RS27825	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
G5C61_RS27840	COG3964	amidohydrolase
G5C61_RS27850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G5C61_RS27860	COG2851	Citrate transporter
G5C61_RS27870	COG0697	spore germination
G5C61_RS27880	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS27885	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS27895	COG1388	LysM domain
G5C61_RS27905	COG3344	reverse transcriptase
G5C61_RS27965	COG0697	spore germination
G5C61_RS27995	COG4221	oxidoreductase activity
G5C61_RS28000	COG0789	Transcriptional regulator
G5C61_RS28025	COG0531	amino acid
G5C61_RS28030	COG0598	Magnesium transport protein CorA
G5C61_RS28045	COG0772	Belongs to the SEDS family
G5C61_RS28055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G5C61_RS28065	COG0569	domain protein
G5C61_RS28070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA