locus-tag	class	description
IM743_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IM743_RS00010	COG0592	DNA-directed DNA polymerase activity
IM743_RS00015	COG2501	S4 domain
IM743_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IM743_RS00030	COG0187	DNA topoisomerase II activity
IM743_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM743_RS00070	COG0517	IMP dehydrogenase activity
IM743_RS00070	COG0516	GMP reductase activity
IM743_RS00075	COG1686	Belongs to the peptidase S11 family
IM743_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IM743_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IM743_RS00100	COG1428	Deoxynucleoside kinase
IM743_RS00105	COG1428	Deoxynucleoside kinase
IM743_RS00110	COG3858	chitin binding
IM743_RS00110	COG1388	LysM domain
IM743_RS00115	COG1335	isochorismatase
IM743_RS00120	COG0590	tRNA wobble adenosine to inosine editing
IM743_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IM743_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IM743_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IM743_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IM743_RS00190	COG3853	Toxic anion resistance protein (TelA)
IM743_RS00195	COG1982	Orn Lys Arg decarboxylase major
IM743_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IM743_RS00205	COG3870	Protein conserved in bacteria
IM743_RS00210	COG1728	Protein conserved in bacteria
IM743_RS00215	COG0470	DNA polymerase III
IM743_RS00220	COG1774	PSP1 C-terminal conserved region
IM743_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IM743_RS00235	COG2827	Endonuclease containing a URI domain
IM743_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IM743_RS00245	COG2002	toxin-antitoxin pair type II binding
IM743_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM743_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM743_RS00255	COG0084	hydrolase, TatD family'
IM743_RS00260	COG3584	3D domain protein
IM743_RS00260	COG3583	domain protein
IM743_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IM743_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IM743_RS00280	COG4466	Protein conserved in bacteria
IM743_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IM743_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM743_RS00300	COG0251	oxidation-reduction process
IM743_RS00305	COG2088	sporulation resulting in formation of a cellular spore
IM743_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IM743_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IM743_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IM743_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
IM743_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IM743_RS00340	COG2002	toxin-antitoxin pair type II binding
IM743_RS00345	COG2244	polysaccharide biosynthetic process
IM743_RS00350	COG3956	TIGRFAM MazG family protein
IM743_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IM743_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IM743_RS00375	COG1098	S1 RNA binding domain
IM743_RS00390	COG2208	phosphoserine phosphatase activity
IM743_RS00395	COG2304	oxidoreductase activity
IM743_RS00400	COG0515	serine threonine protein kinase
IM743_RS00405	COG0037	tRNA processing
IM743_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IM743_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IM743_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IM743_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IM743_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM743_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM743_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM743_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
IM743_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM743_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IM743_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IM743_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IM743_RS00470	COG1396	sequence-specific DNA binding
IM743_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM743_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IM743_RS00565	COG0659	secondary active sulfate transmembrane transporter activity
IM743_RS00570	COG0385	Bile acid
IM743_RS00575	COG2819	hydrolase of the alpha beta superfamily
IM743_RS00580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS00585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS00590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS00595	COG2207	Transcriptional regulator
IM743_RS00595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS00600	COG3876	Protein conserved in bacteria
IM743_RS00605	COG1472	Belongs to the glycosyl hydrolase 3 family
IM743_RS00610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM743_RS00615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS00615	COG1263	PTS System
IM743_RS00620	COG1737	Transcriptional regulator
IM743_RS00625	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IM743_RS00630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS00635	COG1683	Conserved Protein
IM743_RS00665	COG1595	DNA-templated transcription, initiation
IM743_RS00670	COG5662	AntiSigma factor
IM743_RS00675	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IM743_RS00680	COG4856	YbbR-like protein
IM743_RS00685	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM743_RS00700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM743_RS00705	COG3002	Belongs to the UPF0753 family
IM743_RS00710	COG0288	reversible hydration of carbon dioxide
IM743_RS00720	COG5609	conserved protein (DUF2294)
IM743_RS00725	COG0640	Transcriptional regulator
IM743_RS00730	COG2814	Major facilitator Superfamily
IM743_RS00750	COG0596	Alpha beta hydrolase
IM743_RS00755	COG0745	RESPONSE REGULATOR receiver
IM743_RS00760	COG0642	Histidine kinase
IM743_RS00770	COG0515	serine threonine protein kinase
IM743_RS00780	COG1113	amino acid transport
IM743_RS00795	COG2602	Beta-lactamase
IM743_RS00800	COG2124	cytochrome p450
IM743_RS00810	COG0531	amino acid
IM743_RS00820	COG0584	glycerophosphoryl diester phosphodiesterase
IM743_RS00825	COG2271	Major facilitator Superfamily
IM743_RS00835	COG0456	acetyltransferase
IM743_RS00835	COG1846	Transcriptional regulator
IM743_RS00840	COG2271	Major facilitator Superfamily
IM743_RS00850	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS00855	COG0371	Dehydrogenase
IM743_RS00860	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IM743_RS00865	COG3591	Belongs to the peptidase S1B family
IM743_RS00875	COG0596	Alpha beta hydrolase
IM743_RS00880	COG1183	phosphatidylcholine synthase activity
IM743_RS00885	COG0586	Pfam SNARE associated Golgi protein
IM743_RS00890	COG0688	phosphatidylethanolamine metabolic process
IM743_RS00900	COG2312	Erythromycin esterase
IM743_RS00905	COG1054	Belongs to the UPF0176 family
IM743_RS00910	COG1301	dicarboxylic acid transport
IM743_RS00915	COG1263	PTS System
IM743_RS00915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS00915	COG2190	(PTS) system
IM743_RS00920	COG0363	glucosamine-6-phosphate deaminase activity
IM743_RS00925	COG2188	Transcriptional regulator
IM743_RS00935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM743_RS00940	COG0833	amino acid
IM743_RS00945	COG2040	homocysteine
IM743_RS00950	COG1115	amino acid carrier protein
IM743_RS00955	COG2066	Belongs to the glutaminase family
IM743_RS00960	COG4191	Histidine kinase
IM743_RS00965	COG0784	Response regulator, receiver
IM743_RS00970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM743_RS00975	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS00980	COG2271	Major facilitator Superfamily
IM743_RS00985	COG4948	Mandelate Racemase Muconate Lactonizing
IM743_RS00990	COG2186	Transcriptional regulator
IM743_RS00995	COG2721	sulfolactate sulfo-lyase activity
IM743_RS01000	COG3173	Aminoglycoside phosphotransferase
IM743_RS01010	COG0697	spore germination
IM743_RS01015	COG0745	RESPONSE REGULATOR receiver
IM743_RS01020	COG2205	protein histidine kinase activity
IM743_RS01025	COG1131	(ABC) transporter
IM743_RS01045	COG3773	Cell wall hydrolase
IM743_RS01050	COG2304	oxidoreductase activity
IM743_RS01060	COG3540	Alkaline phosphatase
IM743_RS01065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM743_RS01070	COG0805	protein transport
IM743_RS01075	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IM743_RS01080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM743_RS01085	COG0477	Major facilitator Superfamily
IM743_RS01090	COG1309	transcriptional regulator
IM743_RS01095	COG0252	asparaginase activity
IM743_RS01100	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IM743_RS01110	COG1405	negative regulation of cell septum assembly
IM743_RS01110	COG3012	SEC-C Motif Domain Protein
IM743_RS01115	COG3290	protein histidine kinase activity
IM743_RS01120	COG3279	Response regulator of the LytR AlgR family
IM743_RS01125	COG4555	ABC transporter
IM743_RS01130	COG1668	transmembrane transport
IM743_RS01135	COG0667	Aldo Keto reductase
IM743_RS01145	COG1595	DNA-templated transcription, initiation
IM743_RS01150	COG1595	DNA-templated transcription, initiation
IM743_RS01155	COG1876	peptidase activity
IM743_RS01160	COG0457	Tetratricopeptide repeat
IM743_RS01165	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS01170	COG0366	Alpha amylase catalytic
IM743_RS01175	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM743_RS01180	COG1121	(ABC) transporter
IM743_RS01185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM743_RS01190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM743_RS01195	COG2310	stress, protein
IM743_RS01200	COG2310	stress, protein
IM743_RS01205	COG2310	stress, protein
IM743_RS01210	COG0861	Integral membrane protein TerC family
IM743_RS01225	COG1358	cellular component organization or biogenesis
IM743_RS01240	COG3853	Toxic anion resistance protein (TelA)
IM743_RS01245	COG0477	Major facilitator Superfamily
IM743_RS01250	COG2814	Major facilitator Superfamily
IM743_RS01255	COG0640	Transcriptional regulator
IM743_RS01260	COG0517	IMP dehydrogenase activity
IM743_RS01260	COG4175	Glycine betaine
IM743_RS01265	COG4176	ABC-type proline glycine betaine transport system permease component
IM743_RS01270	COG2113	Glycine betaine
IM743_RS01275	COG1473	amidohydrolase
IM743_RS01280	COG1288	antiporter activity
IM743_RS01290	COG0366	Alpha amylase catalytic
IM743_RS01295	COG0039	L-malate dehydrogenase activity
IM743_RS01300	COG1620	l-lactate permease
IM743_RS01305	COG2814	Major facilitator Superfamily
IM743_RS01310	COG1846	Transcriptional regulator
IM743_RS01315	COG1280	lysine exporter protein (LysE YggA)
IM743_RS01320	COG3403	YqcI/YcgG family
IM743_RS01325	COG1113	amino acid transport
IM743_RS01330	COG3665	Urea carboxylase-associated protein
IM743_RS01335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IM743_RS01350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IM743_RS01360	COG3458	cephalosporin-C deacetylase activity
IM743_RS01365	COG3541	Predicted nucleotidyltransferase
IM743_RS01370	COG0506	proline dehydrogenase activity
IM743_RS01375	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS01380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM743_RS01385	COG2508	Transcriptional regulator
IM743_RS01390	COG3689	TIGRFAM TIGR03943 family protein
IM743_RS01395	COG0701	Predicted permease
IM743_RS01400	COG2267	carboxylic ester hydrolase activity
IM743_RS01405	COG0492	ferredoxin-NADP+ reductase activity
IM743_RS01410	COG1587	Uroporphyrinogen-III synthase
IM743_RS01410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM743_RS01415	COG2146	nitrite reductase [NAD(P)H] activity
IM743_RS01420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM743_RS01425	COG0243	molybdopterin cofactor binding
IM743_RS01430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM743_RS01435	COG2223	nitrite transmembrane transporter activity
IM743_RS01440	COG1469	GTP cyclohydrolase I activity
IM743_RS01445	COG1376	ErfK ybiS ycfS ynhG family protein
IM743_RS01455	COG0523	cobalamin synthesis protein
IM743_RS01460	COG0765	amino acid transport
IM743_RS01465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM743_RS01470	COG1063	alcohol dehydrogenase
IM743_RS01475	COG1714	RDD family
IM743_RS01485	COG1846	Transcriptional regulator
IM743_RS01495	COG3842	ATPase activity
IM743_RS01500	COG2723	6-phospho-beta-galactosidase activity
IM743_RS01510	COG3209	COG3209 Rhs family protein
IM743_RS01515	COG3290	protein histidine kinase activity
IM743_RS01515	COG0840	transmembrane signaling receptor activity
IM743_RS01520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IM743_RS01525	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
IM743_RS01530	COG1733	regulation of RNA biosynthetic process
IM743_RS01535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS01540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS01545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS01550	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IM743_RS01555	COG2814	Major facilitator Superfamily
IM743_RS01565	COG0697	spore germination
IM743_RS01570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM743_RS01580	COG2364	Membrane
IM743_RS01585	COG1126	abc transporter atp-binding protein
IM743_RS01590	COG0765	amino acid transport
IM743_RS01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM743_RS01600	COG0583	DNA-binding transcription factor activity
IM743_RS01605	COG0163	prenyltransferase activity
IM743_RS01610	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IM743_RS01625	COG0596	Alpha beta hydrolase
IM743_RS01630	COG3104	oligopeptide transport
IM743_RS01635	COG5434	Belongs to the glycosyl hydrolase 28 family
IM743_RS01645	COG0697	spore germination
IM743_RS01655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM743_RS01660	COG1136	(ABC) transporter
IM743_RS01665	COG0577	efflux transmembrane transporter activity
IM743_RS01670	COG0745	RESPONSE REGULATOR receiver
IM743_RS01675	COG3850	Histidine kinase
IM743_RS01675	COG5002	protein histidine kinase activity
IM743_RS01680	COG0457	Tetratricopeptide repeat
IM743_RS01700	COG0527	aspartate kinase activity
IM743_RS01705	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS01710	COG4605	iron ion homeostasis
IM743_RS01715	COG4604	ABC transporter, ATP-binding protein
IM743_RS01720	COG4607	ABC-type enterochelin transport system periplasmic component
IM743_RS01725	COG2814	Major facilitator Superfamily
IM743_RS01730	COG1309	transcriptional regulator
IM743_RS01735	COG0778	Nitroreductase
IM743_RS01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IM743_RS01745	COG0640	Transcriptional regulator
IM743_RS01750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM743_RS01755	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IM743_RS01760	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS01780	COG4975	Glucose uptake
IM743_RS01785	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS01790	COG4549	nuclear export factor GLE1
IM743_RS01795	COG2372	response to copper ion
IM743_RS01795	COG1276	copper resistance
IM743_RS01800	COG1349	DNA-binding transcription factor activity
IM743_RS01810	COG2213	PTS system mannitol-specific
IM743_RS01815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS01820	COG0246	Mannitol dehydrogenase
IM743_RS01825	COG0473	3-isopropylmalate dehydrogenase activity
IM743_RS01830	COG0412	Dienelactone hydrolase
IM743_RS01835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM743_RS01845	COG0561	phosphatase activity
IM743_RS01850	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IM743_RS01855	COG1914	H( )-stimulated, divalent metal cation uptake system
IM743_RS01860	COG4336	lyase activity
IM743_RS01865	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IM743_RS01870	COG1984	allophanate hydrolase subunit 2
IM743_RS01875	COG1414	Transcriptional regulator
IM743_RS01880	COG2755	lipolytic protein G-D-S-L family
IM743_RS01890	COG2329	Antibiotic biosynthesis monooxygenase
IM743_RS01895	COG0768	penicillin binding
IM743_RS01900	COG4989	oxidoreductase activity
IM743_RS01905	COG3711	transcriptional antiterminator
IM743_RS01910	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS01915	COG2226	methyltransferase
IM743_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS01925	COG1917	Cupin 2, conserved barrel domain protein
IM743_RS01930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS01935	COG3871	stress protein (general stress protein 26)
IM743_RS01945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM743_RS01950	COG2814	Major facilitator Superfamily
IM743_RS01965	COG1522	sequence-specific DNA binding
IM743_RS01970	COG0551	DNA topoisomerase type I activity
IM743_RS01970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM743_RS01975	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IM743_RS01980	COG3706	GGDEF domain
IM743_RS01985	COG5298	Protein conserved in bacteria
IM743_RS01990	COG1215	transferase activity, transferring glycosyl groups
IM743_RS02000	COG0531	amino acid
IM743_RS02005	COG0494	nUDIX hydrolase
IM743_RS02010	COG0028	Belongs to the TPP enzyme family
IM743_RS02020	COG1914	H( )-stimulated, divalent metal cation uptake system
IM743_RS02025	COG2261	transglycosylase associated protein
IM743_RS02030	COG4876	unkown
IM743_RS02035	COG2217	Heavy metal translocating P-type atpase
IM743_RS02040	COG3729	General stress protein
IM743_RS02045	COG0662	Cupin 2, conserved barrel domain protein
IM743_RS02050	COG2329	Antibiotic biosynthesis monooxygenase
IM743_RS02060	COG3546	catalase activity
IM743_RS02065	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IM743_RS02070	COG3290	protein histidine kinase activity
IM743_RS02075	COG4565	transcriptional regulatory protein
IM743_RS02080	COG1301	dicarboxylic acid transport
IM743_RS02090	COG0628	permease
IM743_RS02095	COG1301	dicarboxylic acid transport
IM743_RS02100	COG1131	(ABC) transporter
IM743_RS02105	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IM743_RS02115	COG1960	acyl-CoA dehydrogenase activity
IM743_RS02130	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM743_RS02135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS02140	COG1181	Belongs to the D-alanine--D-alanine ligase family
IM743_RS02145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IM743_RS02150	COG0513	Belongs to the DEAD box helicase family
IM743_RS02155	COG3402	PFAM membrane-flanked domain
IM743_RS02160	COG3428	Bacterial PH domain
IM743_RS02165	COG0705	Rhomboid family
IM743_RS02170	COG0736	holo-[acyl-carrier-protein] synthase activity
IM743_RS02175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IM743_RS02180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM743_RS02185	COG0864	Transcriptional regulator
IM743_RS02190	COG2337	Toxic component of a toxin-antitoxin (TA) module
IM743_RS02195	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS02200	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS02205	COG2172	sigma factor antagonist activity
IM743_RS02210	COG2208	phosphoserine phosphatase activity
IM743_RS02215	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS02220	COG2172	sigma factor antagonist activity
IM743_RS02225	COG1191	sigma factor activity
IM743_RS02230	COG2208	phosphoserine phosphatase activity
IM743_RS02235	COG2183	response to ionizing radiation
IM743_RS02245	COG3091	SprT-like family
IM743_RS02290	COG2072	flavoprotein involved in K transport
IM743_RS02305	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM743_RS02320	COG1846	Transcriptional regulator
IM743_RS02345	COG1476	TRANSCRIPTIONal
IM743_RS02350	COG3239	Fatty acid desaturase
IM743_RS02355	COG1278	Cold shock
IM743_RS02360	COG1278	Cold shock
IM743_RS02365	COG1329	Transcriptional regulator
IM743_RS02370	COG0346	lactoylglutathione lyase activity
IM743_RS02385	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
IM743_RS02395	COG2364	Membrane
IM743_RS02400	COG1846	Transcriptional regulator
IM743_RS02405	COG0456	acetyltransferase
IM743_RS02410	COG2808	Putative FMN-binding domain
IM743_RS02425	COG0693	protein deglycase activity
IM743_RS02435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS02440	COG4257	antibiotic catabolic process
IM743_RS02445	COG0456	acetyltransferase
IM743_RS02450	COG2030	dehydratase
IM743_RS02455	COG0697	spore germination
IM743_RS02460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IM743_RS02465	COG0596	Alpha beta hydrolase
IM743_RS02470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS02475	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IM743_RS02480	COG1522	sequence-specific DNA binding
IM743_RS02490	COG2323	membrane
IM743_RS02495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS02500	COG1309	transcriptional regulator
IM743_RS02510	COG0456	acetyltransferase
IM743_RS02515	COG0488	(ABC) transporter
IM743_RS02520	COG1113	amino acid transport
IM743_RS02525	COG2318	DinB family
IM743_RS02530	COG1846	Transcriptional regulator
IM743_RS02535	COG1033	growth of symbiont in host cell
IM743_RS02535	COG2409	Drug exporters of the RND superfamily
IM743_RS02545	COG0778	Nitroreductase
IM743_RS02550	COG1846	Transcriptional regulator
IM743_RS02555	COG1396	sequence-specific DNA binding
IM743_RS02560	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IM743_RS02570	COG2814	Major facilitator Superfamily
IM743_RS02575	COG0730	response to heat
IM743_RS02580	COG1802	Transcriptional regulator
IM743_RS02585	COG3858	chitin binding
IM743_RS02585	COG1388	LysM domain
IM743_RS02590	COG1819	glycosyl
IM743_RS02600	COG1785	Belongs to the alkaline phosphatase family
IM743_RS02610	COG1078	dGTPase activity
IM743_RS02615	COG1388	LysM domain
IM743_RS02620	COG2814	Major facilitator Superfamily
IM743_RS02625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM743_RS02630	COG1447	Phosphotransferase system cellobiose-specific component IIA
IM743_RS02635	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM743_RS02640	COG2723	6-phospho-beta-galactosidase activity
IM743_RS02645	COG2188	Transcriptional regulator
IM743_RS02650	COG1940	carbohydrate kinase activity
IM743_RS02655	COG1482	cell wall glycoprotein biosynthetic process
IM743_RS02660	COG4124	Belongs to the glycosyl hydrolase 26 family
IM743_RS02705	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IM743_RS02710	COG0802	atpase or kinase
IM743_RS02715	COG1214	PFAM Peptidase M22, glycoprotease
IM743_RS02720	COG0456	acetyltransferase
IM743_RS02725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IM743_RS02730	COG0488	(ABC) transporter
IM743_RS02735	COG0315	cyclic pyranopterin monophosphate synthase activity
IM743_RS02740	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IM743_RS02745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM743_RS02750	COG0805	protein transport
IM743_RS02760	COG1266	CAAX protease self-immunity
IM743_RS02775	COG3279	Response regulator of the LytR AlgR family
IM743_RS02790	COG3290	protein histidine kinase activity
IM743_RS02870	COG0457	Tetratricopeptide repeat
IM743_RS02875	COG1063	alcohol dehydrogenase
IM743_RS02880	COG2211	Major facilitator Superfamily
IM743_RS02885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM743_RS02895	COG2814	Major facilitator Superfamily
IM743_RS02900	COG1063	alcohol dehydrogenase
IM743_RS02905	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IM743_RS02910	COG0823	Involved in the tonB-independent uptake of proteins
IM743_RS02925	COG2267	carboxylic ester hydrolase activity
IM743_RS02935	COG2132	Multicopper oxidase
IM743_RS02940	COG1113	amino acid transport
IM743_RS02945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IM743_RS02950	COG0714	Associated with various cellular activities
IM743_RS02955	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
IM743_RS02960	COG1305	Transglutaminase-like
IM743_RS02965	COG0519	Catalyzes the synthesis of GMP from XMP
IM743_RS02965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IM743_RS02970	COG2252	PERMEase
IM743_RS02975	COG3064	Membrane
IM743_RS02985	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IM743_RS02995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IM743_RS03000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IM743_RS03005	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IM743_RS03010	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IM743_RS03015	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM743_RS03020	COG0047	phosphoribosylformylglycinamidine synthase activity
IM743_RS03025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IM743_RS03030	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IM743_RS03035	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IM743_RS03040	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IM743_RS03045	COG0138	bifunctional purine biosynthesis protein purh
IM743_RS03050	COG0151	Belongs to the GarS family
IM743_RS03055	COG1522	sequence-specific DNA binding
IM743_RS03060	COG0531	amino acid
IM743_RS03070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IM743_RS03075	COG1470	cell adhesion involved in biofilm formation
IM743_RS03080	COG4496	protein, YerC YecD
IM743_RS03085	COG0069	glutamate synthase activity
IM743_RS03090	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IM743_RS03095	COG0210	DNA helicase
IM743_RS03100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IM743_RS03105	COG4851	CamS sex pheromone cAM373 precursor
IM743_RS03110	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM743_RS03115	COG1285	pathogenesis
IM743_RS03120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM743_RS03125	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM743_RS03130	COG0154	amidase activity
IM743_RS03135	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IM743_RS03140	COG1309	transcriptional regulator
IM743_RS03145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IM743_RS03150	COG1597	lipid kinase activity
IM743_RS03155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM743_RS03165	COG0457	Tetratricopeptide repeat
IM743_RS03200	COG3586	endonuclease activity
IM743_RS03210	COG0457	Tetratricopeptide repeat
IM743_RS03220	COG0217	transcriptional regulatory protein
IM743_RS03235	COG1309	transcriptional regulator
IM743_RS03240	COG3631	Ketosteroid isomerase-related protein
IM743_RS03245	COG0702	epimerase
IM743_RS03265	COG3546	catalase activity
IM743_RS03270	COG0454	-acetyltransferase
IM743_RS03280	COG5578	integral membrane protein
IM743_RS03285	COG2972	Histidine kinase
IM743_RS03290	COG4753	response regulator
IM743_RS03290	COG2207	Transcriptional regulator
IM743_RS03295	COG1653	transport
IM743_RS03300	COG1175	transmembrane transport
IM743_RS03305	COG0395	ABC-type sugar transport system, permease component
IM743_RS03310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IM743_RS03315	COG2207	Transcriptional regulator
IM743_RS03320	COG2755	lipolytic protein G-D-S-L family
IM743_RS03330	COG5578	integral membrane protein
IM743_RS03335	COG3401	FG-GAP repeat protein
IM743_RS03340	COG3401	FG-GAP repeat protein
IM743_RS03345	COG0667	Aldo Keto reductase
IM743_RS03350	COG2755	lipolytic protein G-D-S-L family
IM743_RS03355	COG1874	Beta-galactosidase
IM743_RS03365	COG1653	transport
IM743_RS03370	COG4209	transmembrane transport
IM743_RS03375	COG0395	ABC-type sugar transport system, permease component
IM743_RS03380	COG1486	melibiose metabolic process
IM743_RS03385	COG2323	membrane
IM743_RS03390	COG2329	Antibiotic biosynthesis monooxygenase
IM743_RS03395	COG0346	lactoylglutathione lyase activity
IM743_RS03405	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS03410	COG5583	Uncharacterized small protein (DUF2292)
IM743_RS03415	COG0670	Belongs to the BI1 family
IM743_RS03420	COG1846	Transcriptional regulator
IM743_RS03425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM743_RS03435	COG2124	cytochrome p450
IM743_RS03435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM743_RS03440	COG1368	sulfuric ester hydrolase activity
IM743_RS03445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IM743_RS03450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS03455	COG1442	glycosyl transferase family 8
IM743_RS03460	COG1216	Glycosyl transferase, family 2
IM743_RS03465	COG1442	glycosyl transferase family 8
IM743_RS03470	COG2223	nitrite transmembrane transporter activity
IM743_RS03475	COG1011	Hydrolase
IM743_RS03480	COG0531	amino acid
IM743_RS03485	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS03490	COG0840	transmembrane signaling receptor activity
IM743_RS03495	COG0488	(ABC) transporter
IM743_RS03505	COG0789	Transcriptional regulator
IM743_RS03510	COG2814	Major facilitator Superfamily
IM743_RS03520	COG0488	(ABC) transporter
IM743_RS03525	COG0513	Belongs to the DEAD box helicase family
IM743_RS03535	COG2130	NADP-dependent
IM743_RS03540	COG1120	ATPase activity
IM743_RS03545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS03550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS03555	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IM743_RS03570	COG3866	Pectate lyase
IM743_RS03575	COG0471	metal ion transport
IM743_RS03580	COG3290	protein histidine kinase activity
IM743_RS03585	COG4565	transcriptional regulatory protein
IM743_RS03590	COG3181	Tripartite tricarboxylate transporter family receptor
IM743_RS03595	COG2851	Citrate transporter
IM743_RS03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS03605	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IM743_RS03610	COG1254	Belongs to the acylphosphatase family
IM743_RS03615	COG2258	MOSC domain
IM743_RS03635	COG0024	Methionine aminopeptidase
IM743_RS03640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS03640	COG1263	PTS System
IM743_RS03645	COG1368	sulfuric ester hydrolase activity
IM743_RS03655	COG1115	amino acid carrier protein
IM743_RS03660	COG1263	PTS System
IM743_RS03660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS03665	COG0366	Alpha amylase catalytic
IM743_RS03670	COG2188	Transcriptional regulator
IM743_RS03675	COG0778	Nitroreductase
IM743_RS03680	COG0737	Belongs to the 5'-nucleotidase family
IM743_RS03685	COG0693	protein deglycase activity
IM743_RS03690	COG2814	Major facilitator Superfamily
IM743_RS03695	COG4840	Belongs to the UPF0435 family
IM743_RS03700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM743_RS03705	COG4980	gas vesicle protein
IM743_RS03710	COG1295	ribonuclease BN
IM743_RS03715	COG0477	Major facilitator Superfamily
IM743_RS03720	COG0387	Pfam Sodium calcium exchanger
IM743_RS03730	COG0668	transmembrane transport
IM743_RS03735	COG0535	radical SAM domain protein
IM743_RS03745	COG0726	polysaccharide deacetylase
IM743_RS03750	COG2084	Dehydrogenase
IM743_RS03755	COG0598	Magnesium transport protein CorA
IM743_RS03760	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IM743_RS03765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IM743_RS03770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IM743_RS03780	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IM743_RS03795	COG4637	Psort location Cytoplasmic, score
IM743_RS03805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM743_RS03810	COG0022	dehydrogenase e1 component
IM743_RS03815	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM743_RS03820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM743_RS03825	COG3284	Transcriptional regulator
IM743_RS03835	COG1742	UPF0060 membrane protein
IM743_RS03860	COG4842	Belongs to the WXG100 family
IM743_RS03865	COG1486	melibiose metabolic process
IM743_RS03870	COG1737	Transcriptional regulator
IM743_RS03875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS03875	COG1263	PTS System
IM743_RS03880	COG1132	(ABC) transporter
IM743_RS03885	COG1132	(ABC) transporter
IM743_RS03890	COG2259	Doxx family
IM743_RS03895	COG2514	catechol 2,3-dioxygenase activity
IM743_RS03900	COG4585	Histidine kinase
IM743_RS03905	COG2197	response regulator
IM743_RS03910	COG1131	(ABC) transporter
IM743_RS03915	COG0842	Transport permease protein
IM743_RS03915	COG1511	domain protein
IM743_RS03920	COG0842	Transport permease protein
IM743_RS03930	COG1695	Transcriptional regulator
IM743_RS03935	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IM743_RS03940	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IM743_RS03945	COG2318	DinB family
IM743_RS03950	COG2814	Major facilitator Superfamily
IM743_RS03955	COG1846	Transcriptional regulator
IM743_RS03960	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IM743_RS03960	COG0392	lysyltransferase activity
IM743_RS03965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS03970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS03980	COG0384	phenazine biosynthesis protein PhzF
IM743_RS03985	COG0778	Nitroreductase
IM743_RS04000	COG1090	epimerase
IM743_RS04005	COG2137	regulation of response to DNA damage stimulus
IM743_RS04015	COG2814	Major facilitator Superfamily
IM743_RS04035	COG1476	TRANSCRIPTIONal
IM743_RS04040	COG3103	Sh3 type 3 domain protein
IM743_RS04045	COG5658	integral membrane protein
IM743_RS04050	COG0596	Alpha beta hydrolase
IM743_RS04055	COG0463	Glycosyl transferase, family 2
IM743_RS04060	COG4485	Bacterial membrane protein, YfhO
IM743_RS04065	COG1988	membrane-bound metal-dependent
IM743_RS04070	COG1194	a g-specific adenine glycosylase
IM743_RS04080	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS04095	COG3557	Belongs to the UPF0374 family
IM743_RS04100	COG1132	(ABC) transporter
IM743_RS04105	COG4129	membrane
IM743_RS04110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM743_RS04115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IM743_RS04120	COG0735	belongs to the Fur family
IM743_RS04230	COG4326	sporulation control protein
IM743_RS04240	COG1063	alcohol dehydrogenase
IM743_RS04245	COG5577	PFAM Coat F domain
IM743_RS04255	COG3340	Belongs to the peptidase S51 family
IM743_RS04260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IM743_RS04270	COG0753	catalase activity
IM743_RS04275	COG1116	anion transmembrane transporter activity
IM743_RS04280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM743_RS04285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM743_RS04290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM743_RS04300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IM743_RS04310	COG1476	TRANSCRIPTIONal
IM743_RS04320	COG3382	B3 4 domain protein
IM743_RS04325	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IM743_RS04335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IM743_RS04340	COG0789	Transcriptional regulator
IM743_RS04345	COG1664	Polymer-forming cytoskeletal
IM743_RS04350	COG1664	Polymer-forming cytoskeletal
IM743_RS04355	COG2766	serine protein kinase
IM743_RS04360	COG2718	Belongs to the UPF0229 family
IM743_RS04365	COG1846	Transcriptional regulator
IM743_RS04370	COG1566	PFAM secretion protein HlyD family protein
IM743_RS04375	COG2814	Major facilitator Superfamily
IM743_RS04380	COG0655	NAD(P)H dehydrogenase (quinone) activity
IM743_RS04395	COG1725	Transcriptional regulator
IM743_RS04400	COG1131	(ABC) transporter
IM743_RS04405	COG1131	(ABC) transporter
IM743_RS04410	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IM743_RS04415	COG1278	Cold shock
IM743_RS04420	COG1464	Belongs to the NlpA lipoprotein family
IM743_RS04425	COG3706	GGDEF domain
IM743_RS04430	COG1823	symporter activity
IM743_RS04470	COG5577	PFAM Coat F domain
IM743_RS04475	COG0737	Belongs to the 5'-nucleotidase family
IM743_RS04475	COG4085	toxin activity
IM743_RS04475	COG1525	nuclease
IM743_RS04480	COG3764	Sortase (surface protein transpeptidase)
IM743_RS04485	COG0564	pseudouridine synthase activity
IM743_RS04495	COG0517	IMP dehydrogenase activity
IM743_RS04500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM743_RS04505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM743_RS04505	COG3153	acetyltransferase
IM743_RS04515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM743_RS04520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IM743_RS04525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IM743_RS04530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IM743_RS04535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IM743_RS04540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IM743_RS04545	COG4585	Histidine kinase
IM743_RS04545	COG2203	Gaf domain
IM743_RS04550	COG2197	response regulator
IM743_RS04555	COG0431	NADPH-dependent FMN reductase
IM743_RS04570	COG1388	LysM domain
IM743_RS04570	COG0791	NLP P60 protein
IM743_RS04575	COG1959	2 iron, 2 sulfur cluster binding
IM743_RS04580	COG0668	transmembrane transport
IM743_RS04585	COG2719	SpoVR family
IM743_RS04590	COG1785	Belongs to the alkaline phosphatase family
IM743_RS04595	COG0791	NLP P60 protein
IM743_RS04595	COG1388	LysM domain
IM743_RS04600	COG0583	DNA-binding transcription factor activity
IM743_RS04605	COG0372	Belongs to the citrate synthase family
IM743_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS04615	COG0531	amino acid
IM743_RS04620	COG0733	neurotransmitter:sodium symporter activity
IM743_RS04630	COG0456	acetyltransferase
IM743_RS04645	COG1595	DNA-templated transcription, initiation
IM743_RS04650	COG0667	Aldo Keto reductase
IM743_RS04655	COG0204	Acyl-transferase
IM743_RS04660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM743_RS04665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS04670	COG1253	flavin adenine dinucleotide binding
IM743_RS04675	COG0789	Transcriptional regulator
IM743_RS04680	COG0436	Aminotransferase
IM743_RS04690	COG1253	flavin adenine dinucleotide binding
IM743_RS04695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM743_RS04700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IM743_RS04705	COG0584	glycerophosphoryl diester phosphodiesterase
IM743_RS04715	COG0668	transmembrane transport
IM743_RS04720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IM743_RS04725	COG0726	polysaccharide deacetylase
IM743_RS04730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM743_RS04735	COG1757	Na H antiporter
IM743_RS04740	COG0589	response to stress
IM743_RS04745	COG1132	(ABC) transporter
IM743_RS04750	COG1132	(ABC) transporter
IM743_RS04755	COG0702	epimerase
IM743_RS04775	COG0189	ligase activity
IM743_RS04780	COG0189	ligase activity
IM743_RS04785	COG4399	Belongs to the UPF0754 family
IM743_RS04790	COG3679	Belongs to the UPF0342 family
IM743_RS04795	COG4335	DNA alkylation repair
IM743_RS04800	COG0561	phosphatase activity
IM743_RS04805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM743_RS04810	COG0475	glutathione-regulated potassium exporter activity
IM743_RS04815	COG0490	domain, Protein
IM743_RS04825	COG1024	Enoyl-CoA hydratase
IM743_RS04835	COG4152	abc transporter atp-binding protein
IM743_RS04840	COG1668	transmembrane transport
IM743_RS04845	COG0420	3'-5' exonuclease activity
IM743_RS04850	COG4717	serine-type aminopeptidase activity
IM743_RS04855	COG3481	metal-dependent phosphohydrolase, HD sub domain
IM743_RS04865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IM743_RS04895	COG1846	Transcriptional regulator
IM743_RS04900	COG4980	gas vesicle protein
IM743_RS04915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IM743_RS04920	COG0537	adenosine 5'-monophosphoramidase activity
IM743_RS04925	COG1131	(ABC) transporter
IM743_RS04930	COG4473	ABC transporter
IM743_RS04940	COG1473	amidohydrolase
IM743_RS04945	COG3069	C4-dicarboxylate transmembrane transporter activity
IM743_RS04950	COG2329	Antibiotic biosynthesis monooxygenase
IM743_RS04955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM743_RS04960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IM743_RS04965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IM743_RS04970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IM743_RS04975	COG1309	transcriptional regulator
IM743_RS04980	COG1511	domain protein
IM743_RS04985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM743_RS04990	COG4377	Putative membrane peptidase family (DUF2324)
IM743_RS05000	COG1363	Peptidase, m42
IM743_RS05005	COG4405	Protein conserved in bacteria
IM743_RS05010	COG1301	dicarboxylic acid transport
IM743_RS05020	COG1234	tRNA 3'-trailer cleavage
IM743_RS05025	COG0095	Lipoate-protein ligase
IM743_RS05030	COG0702	epimerase
IM743_RS05035	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS05045	COG0501	Belongs to the peptidase M48B family
IM743_RS05050	COG1404	Belongs to the peptidase S8 family
IM743_RS05055	COG0456	acetyltransferase
IM743_RS05060	COG0604	alcohol dehydrogenase
IM743_RS05065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IM743_RS05070	COG0406	alpha-ribazole phosphatase activity
IM743_RS05075	COG0183	Belongs to the thiolase family
IM743_RS05080	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS05085	COG1268	BioY protein
IM743_RS05090	COG0840	transmembrane signaling receptor activity
IM743_RS05095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM743_RS05095	COG0723	plastoquinol--plastocyanin reductase activity
IM743_RS05100	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS05110	COG4903	ComK protein
IM743_RS05115	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS05125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM743_RS05140	COG0398	Pfam SNARE associated Golgi protein
IM743_RS05145	COG0681	Belongs to the peptidase S26 family
IM743_RS05150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IM743_RS05155	COG1846	Transcriptional regulator
IM743_RS05165	COG0738	Major facilitator superfamily
IM743_RS05170	COG0673	inositol 2-dehydrogenase activity
IM743_RS05175	COG0561	phosphatase activity
IM743_RS05180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM743_RS05185	COG1609	Transcriptional regulator
IM743_RS05190	COG3180	Ammonia monooxygenase
IM743_RS05200	COG4533	DNA binding
IM743_RS05210	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
IM743_RS05215	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IM743_RS05220	COG1074	ATP-dependent DNA helicase activity
IM743_RS05225	COG0420	3'-5' exonuclease activity
IM743_RS05230	COG0419	ATPase involved in DNA repair
IM743_RS05235	COG1403	HNH endonuclease
IM743_RS05275	COG5337	Spore coat protein CotH
IM743_RS05280	COG0179	Fumarylacetoacetate (FAA) hydrolase
IM743_RS05290	COG1404	Belongs to the peptidase S8 family
IM743_RS05300	COG0367	asparagine synthase
IM743_RS05305	COG2318	DinB family
IM743_RS05310	COG1562	ergosterol biosynthetic process
IM743_RS05315	COG0534	Mate efflux family protein
IM743_RS05320	COG1917	Cupin 2, conserved barrel domain protein
IM743_RS05320	COG2207	Transcriptional regulator
IM743_RS05325	COG1609	Transcriptional regulator
IM743_RS05330	COG0673	inositol 2-dehydrogenase activity
IM743_RS05335	COG2318	DinB family
IM743_RS05345	COG1357	PFAM Pentapeptide repeats (8 copies)
IM743_RS05350	COG2267	carboxylic ester hydrolase activity
IM743_RS05355	COG0529	Catalyzes the synthesis of activated sulfate
IM743_RS05360	COG2046	Belongs to the sulfate adenylyltransferase family
IM743_RS05365	COG0175	sulfate reduction
IM743_RS05370	COG2045	Belongs to the ComB family
IM743_RS05375	COG1809	phosphosulfolactate synthase activity
IM743_RS05380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS05385	COG4948	Mandelate Racemase Muconate Lactonizing
IM743_RS05390	COG2814	Major facilitator Superfamily
IM743_RS05395	COG0454	-acetyltransferase
IM743_RS05400	COG2153	protein acetylation
IM743_RS05405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IM743_RS05405	COG0646	methionine synthase
IM743_RS05410	COG1666	GTP binding
IM743_RS05415	COG2996	Protein conserved in bacteria
IM743_RS05435	COG1695	Transcriptional regulator
IM743_RS05450	COG3227	Zinc metalloprotease (Elastase)
IM743_RS05455	COG1307	EDD domain protein, DegV family
IM743_RS05460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS05480	COG0561	phosphatase activity
IM743_RS05485	COG1073	alpha beta
IM743_RS05490	COG2151	metal-sulfur cluster biosynthetic enzyme
IM743_RS05500	COG0277	FAD linked oxidase domain protein
IM743_RS05505	COG2271	Major facilitator Superfamily
IM743_RS05510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IM743_RS05515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IM743_RS05525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM743_RS05530	COG0505	Belongs to the CarA family
IM743_RS05535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM743_RS05540	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IM743_RS05555	COG2267	carboxylic ester hydrolase activity
IM743_RS05565	COG1744	ABC transporter substrate-binding protein PnrA-like
IM743_RS05580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM743_RS05585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM743_RS05590	COG5504	Zn-dependent protease
IM743_RS05595	COG0444	Belongs to the ABC transporter superfamily
IM743_RS05600	COG4608	Belongs to the ABC transporter superfamily
IM743_RS05610	COG0601	transmembrane transport
IM743_RS05615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM743_RS05625	COG0180	Tryptophanyl-tRNA synthetase
IM743_RS05630	COG4166	transmembrane transport
IM743_RS05635	COG0601	transmembrane transport
IM743_RS05640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM743_RS05645	COG0444	Belongs to the ABC transporter superfamily
IM743_RS05650	COG4608	Belongs to the ABC transporter superfamily
IM743_RS05655	COG2814	Major facilitator Superfamily
IM743_RS05660	COG0456	acetyltransferase
IM743_RS05665	COG1393	Belongs to the ArsC family
IM743_RS05670	COG0861	Integral membrane protein TerC family
IM743_RS05680	COG4862	establishment of competence for transformation
IM743_RS05685	COG4469	Competence protein
IM743_RS05690	COG1164	Oligoendopeptidase f
IM743_RS05700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IM743_RS05705	COG2346	COG2346, Truncated hemoglobins
IM743_RS05710	COG0741	lytic transglycosylase activity
IM743_RS05715	COG4116	CYTH
IM743_RS05725	COG2357	RelA SpoT domain protein
IM743_RS05730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM743_RS05735	COG0564	pseudouridine synthase activity
IM743_RS05740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IM743_RS05745	COG0569	domain protein
IM743_RS05745	COG0475	glutathione-regulated potassium exporter activity
IM743_RS05750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IM743_RS05755	COG0352	thiamine-phosphate diphosphorylase activity
IM743_RS05760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM743_RS05765	COG2104	thiamine diphosphate biosynthetic process
IM743_RS05770	COG2022	thiamine diphosphate biosynthetic process
IM743_RS05775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM743_RS05780	COG0351	phosphomethylpyrimidine kinase
IM743_RS05785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IM743_RS05840	COG0210	DNA helicase
IM743_RS05850	COG2153	protein acetylation
IM743_RS05855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IM743_RS05860	COG2382	esterase
IM743_RS05865	COG0626	cystathionine gamma-synthase activity
IM743_RS05870	COG0626	cystathionine gamma-synthase activity
IM743_RS05880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS05885	COG5505	Protein of unknown function (DUF819)
IM743_RS05900	COG2856	Zn peptidase
IM743_RS05915	COG5444	nuclease activity
IM743_RS05955	COG2337	Toxic component of a toxin-antitoxin (TA) module
IM743_RS05980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IM743_RS05990	COG2318	DinB family
IM743_RS06015	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS06035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS06045	COG0789	Transcriptional regulator
IM743_RS06060	COG0109	protoheme IX farnesyltransferase activity
IM743_RS06070	COG0726	polysaccharide deacetylase
IM743_RS06085	COG5504	Zn-dependent protease
IM743_RS06090	COG2205	protein histidine kinase activity
IM743_RS06100	COG3383	formate dehydrogenase (NAD+) activity
IM743_RS06105	COG2427	Protein of unknown function (DUF1641)
IM743_RS06115	COG1051	belongs to the nudix hydrolase family
IM743_RS06125	COG2124	cytochrome p450
IM743_RS06130	COG1819	glycosyl
IM743_RS06145	COG1587	Uroporphyrinogen-III synthase
IM743_RS06150	COG0390	transport system, permease component
IM743_RS06155	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM743_RS06160	COG0697	spore germination
IM743_RS06165	COG4297	protein containing double-stranded beta helix domain
IM743_RS06175	COG1252	NADH dehydrogenase
IM743_RS06180	COG1904	glucuronate isomerase
IM743_RS06185	COG2211	Major facilitator Superfamily
IM743_RS06190	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IM743_RS06195	COG1063	alcohol dehydrogenase
IM743_RS06200	COG1312	Catalyzes the dehydration of D-mannonate
IM743_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS06210	COG2271	Major facilitator Superfamily
IM743_RS06215	COG1609	Transcriptional regulator
IM743_RS06220	COG0246	Mannitol dehydrogenase
IM743_RS06225	COG2721	sulfolactate sulfo-lyase activity
IM743_RS06230	COG0730	response to heat
IM743_RS06235	COG2318	DinB family
IM743_RS06240	COG0457	Tetratricopeptide repeat
IM743_RS06250	COG2350	Protein conserved in bacteria
IM743_RS06255	COG1388	LysM domain
IM743_RS06255	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS06255	COG5632	N-Acetylmuramoyl-L-alanine amidase
IM743_RS06265	COG4195	phage-related replication protein
IM743_RS06270	COG3546	catalase activity
IM743_RS06275	COG2856	Zn peptidase
IM743_RS06280	COG1396	sequence-specific DNA binding
IM743_RS06290	COG1522	sequence-specific DNA binding
IM743_RS06295	COG1484	DNA-dependent DNA replication
IM743_RS06315	COG1595	DNA-templated transcription, initiation
IM743_RS06320	COG5484	DNA packaging
IM743_RS06320	COG3728	DNA packaging
IM743_RS06325	COG1783	phage Terminase large subunit
IM743_RS06330	COG5518	Phage portal protein
IM743_RS06335	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IM743_RS06340	COG4653	Phage capsid family
IM743_RS06390	COG5412	phage tail tape measure protein
IM743_RS06390	COG3953	SLT domain
IM743_RS06390	COG5412	phage tail tape measure protein
IM743_RS06390	COG3953	SLT domain
IM743_RS06390	COG3953	SLT domain
IM743_RS06390	COG5412	phage tail tape measure protein
IM743_RS06395	COG1652	LysM domain
IM743_RS06400	COG4193	domain, Protein
IM743_RS06410	COG3628	GPW Gp25 family protein
IM743_RS06415	COG3299	homolog of phage Mu protein gp47
IM743_RS06420	COG3778	Protein conserved in bacteria
IM743_RS06460	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS06460	COG5632	N-Acetylmuramoyl-L-alanine amidase
IM743_RS06480	COG0306	phosphate transporter
IM743_RS06485	COG1392	Phosphate transport regulator
IM743_RS06490	COG0531	amino acid
IM743_RS06495	COG0346	lactoylglutathione lyase activity
IM743_RS06500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM743_RS06505	COG0463	Glycosyl transferase, family 2
IM743_RS06515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM743_RS06520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM743_RS06525	COG2362	D-Aminopeptidase
IM743_RS06530	COG0601	transmembrane transport
IM743_RS06535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IM743_RS06540	COG0444	Belongs to the ABC transporter superfamily
IM743_RS06545	COG4166	transmembrane transport
IM743_RS06550	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM743_RS06555	COG4948	Mandelate Racemase Muconate Lactonizing
IM743_RS06560	COG0791	NLP P60 protein
IM743_RS06565	COG4608	Belongs to the ABC transporter superfamily
IM743_RS06570	COG2706	6-phosphogluconolactonase activity
IM743_RS06575	COG1834	amidinotransferase
IM743_RS06580	COG1607	acyl-coa hydrolase
IM743_RS06585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IM743_RS06585	COG1017	nitric oxide dioxygenase activity
IM743_RS06595	COG2323	membrane
IM743_RS06600	COG2318	DinB family
IM743_RS06605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS06610	COG2076	Multidrug Resistance protein
IM743_RS06615	COG2076	Multidrug Resistance protein
IM743_RS06620	COG0788	formyltetrahydrofolate deformylase activity
IM743_RS06625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM743_RS06630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IM743_RS06635	COG1764	response to oxidative stress
IM743_RS06640	COG1846	Transcriptional regulator
IM743_RS06645	COG1764	response to oxidative stress
IM743_RS06655	COG0590	tRNA wobble adenosine to inosine editing
IM743_RS06660	COG0406	alpha-ribazole phosphatase activity
IM743_RS06665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM743_RS06670	COG1404	Belongs to the peptidase S8 family
IM743_RS06675	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS06680	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IM743_RS06685	COG1122	ATPase activity
IM743_RS06690	COG4721	ABC-type cobalt transport system, permease component
IM743_RS06700	COG0745	RESPONSE REGULATOR receiver
IM743_RS06705	COG3850	Histidine kinase
IM743_RS06705	COG5002	protein histidine kinase activity
IM743_RS06710	COG3212	peptidase
IM743_RS06715	COG3212	peptidase
IM743_RS06725	COG2239	Acts as a magnesium transporter
IM743_RS06730	COG0789	Transcriptional regulator
IM743_RS06745	COG1846	Transcriptional regulator
IM743_RS06750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM743_RS06755	COG0726	polysaccharide deacetylase
IM743_RS06760	COG1408	metallophosphoesterase
IM743_RS06770	COG0463	Glycosyl transferase, family 2
IM743_RS06775	COG3285	dna ligase
IM743_RS06775	COG1793	dna ligase
IM743_RS06780	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IM743_RS06785	COG5001	Diguanylate cyclase
IM743_RS06785	COG3300	MHYT domain
IM743_RS06790	COG0586	Pfam SNARE associated Golgi protein
IM743_RS06795	COG0861	Integral membrane protein TerC family
IM743_RS06800	COG1191	sigma factor activity
IM743_RS06820	COG0501	Belongs to the peptidase M48B family
IM743_RS06825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM743_RS06840	COG3594	Acyltransferase
IM743_RS06845	COG5002	protein histidine kinase activity
IM743_RS06850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IM743_RS06860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IM743_RS06865	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IM743_RS06870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IM743_RS06875	COG0436	Aminotransferase
IM743_RS06880	COG1850	ribulose-bisphosphate carboxylase activity
IM743_RS06885	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IM743_RS06890	COG0235	Class ii aldolase
IM743_RS06895	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IM743_RS06900	COG3339	Conserved Protein
IM743_RS06915	COG3852	Histidine kinase
IM743_RS06920	COG1846	Transcriptional regulator
IM743_RS06925	COG1360	Flagellar Motor Protein
IM743_RS06930	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM743_RS06935	COG0542	response to heat
IM743_RS06940	COG3949	Membrane
IM743_RS06945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IM743_RS06950	COG0720	synthase
IM743_RS06955	COG0602	queuosine metabolic process
IM743_RS06960	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IM743_RS06965	COG1388	LysM domain
IM743_RS06965	COG4641	Protein conserved in bacteria
IM743_RS06970	COG1388	LysM domain
IM743_RS06985	COG4873	Protein conserved in bacteria
IM743_RS06995	COG3773	Cell wall hydrolase
IM743_RS07000	COG2244	polysaccharide biosynthetic process
IM743_RS07005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS07010	COG2217	Heavy metal translocating P-type atpase
IM743_RS07020	COG0006	proline dipeptidase activity
IM743_RS07025	COG1609	Transcriptional regulator
IM743_RS07030	COG3711	transcriptional antiterminator
IM743_RS07035	COG2190	(PTS) system
IM743_RS07035	COG1263	PTS System
IM743_RS07035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS07040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS07045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IM743_RS07055	COG1533	DNA photolyase activity
IM743_RS07060	COG0456	acetyltransferase
IM743_RS07065	COG0840	transmembrane signaling receptor activity
IM743_RS07070	COG2084	Dehydrogenase
IM743_RS07075	COG2340	Cysteine-rich secretory protein family
IM743_RS07080	COG0768	penicillin binding
IM743_RS07085	COG4191	Histidine kinase
IM743_RS07090	COG0436	Aminotransferase
IM743_RS07100	COG0784	Response regulator, receiver
IM743_RS07100	COG0835	chemotaxis
IM743_RS07110	COG2814	Major facilitator Superfamily
IM743_RS07115	COG1376	ErfK ybiS ycfS ynhG family protein
IM743_RS07120	COG1408	metallophosphoesterase
IM743_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS07130	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS07140	COG2200	EAL domain
IM743_RS07150	COG4703	Protein of unknown function (DUF1797)
IM743_RS07155	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
IM743_RS07165	COG0517	IMP dehydrogenase activity
IM743_RS07170	COG0583	DNA-binding transcription factor activity
IM743_RS07175	COG0716	FMN binding
IM743_RS07185	COG0716	FMN binding
IM743_RS07190	COG2171	N-acyltransferase activity
IM743_RS07195	COG1473	amidohydrolase
IM743_RS07205	COG0668	transmembrane transport
IM743_RS07210	COG0450	alkyl hydroperoxide reductase
IM743_RS07215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS07230	COG0746	molybdenum cofactor guanylyltransferase activity
IM743_RS07235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IM743_RS07240	COG0303	'Molybdopterin
IM743_RS07245	COG1763	Mo-molybdopterin cofactor biosynthetic process
IM743_RS07250	COG0314	molybdopterin synthase activity
IM743_RS07255	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IM743_RS07260	COG1132	(ABC) transporter
IM743_RS07265	COG1132	(ABC) transporter
IM743_RS07275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM743_RS07280	COG1136	(ABC) transporter
IM743_RS07285	COG0577	efflux transmembrane transporter activity
IM743_RS07290	COG1349	DNA-binding transcription factor activity
IM743_RS07295	COG1105	Belongs to the carbohydrate kinase PfkB family
IM743_RS07300	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM743_RS07300	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IM743_RS07300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS07305	COG0681	Belongs to the peptidase S26 family
IM743_RS07320	COG0488	(ABC) transporter
IM743_RS07325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM743_RS07330	COG2309	aminopeptidase activity
IM743_RS07340	COG1077	Cell shape determining protein MreB Mrl
IM743_RS07345	COG2002	toxin-antitoxin pair type II binding
IM743_RS07350	COG3852	Histidine kinase
IM743_RS07355	COG2105	PFAM AIG2 family protein
IM743_RS07355	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IM743_RS07360	COG0569	domain protein
IM743_RS07365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IM743_RS07370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IM743_RS07375	COG5503	Protein of unknown function (DUF1447)
IM743_RS07380	COG0561	phosphatase activity
IM743_RS07385	COG0242	peptide deformylase activity
IM743_RS07395	COG0497	DNA recombination
IM743_RS07400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM743_RS07405	COG0022	dehydrogenase e1 component
IM743_RS07410	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM743_RS07415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM743_RS07420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS07430	COG1982	Orn Lys Arg decarboxylase major
IM743_RS07435	COG4476	Belongs to the UPF0223 family
IM743_RS07440	COG4493	Belongs to the UPF0637 family
IM743_RS07450	COG0483	inositol monophosphate 1-phosphatase activity
IM743_RS07460	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IM743_RS07485	COG1595	DNA-templated transcription, initiation
IM743_RS07505	COG1217	gtp-binding protein TYPA
IM743_RS07515	COG4896	Protein conserved in bacteria
IM743_RS07525	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IM743_RS07530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM743_RS07535	COG2066	Belongs to the glutaminase family
IM743_RS07540	COG4838	Belongs to the UPF0358 family
IM743_RS07545	COG0772	Belongs to the SEDS family
IM743_RS07550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IM743_RS07560	COG1612	heme a metabolic process
IM743_RS07565	COG0109	protoheme IX farnesyltransferase activity
IM743_RS07570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM743_RS07570	COG2010	Cytochrome c
IM743_RS07575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM743_RS07580	COG1845	cytochrome c oxidase, subunit III
IM743_RS07585	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IM743_RS07590	COG3336	cytochrome c oxidase
IM743_RS07600	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
IM743_RS07605	COG2340	Cysteine-rich secretory protein family
IM743_RS07620	COG3679	Belongs to the UPF0342 family
IM743_RS07625	COG4471	UPF0298 protein
IM743_RS07630	COG0742	ribosomal rna small subunit methyltransferase
IM743_RS07635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IM743_RS07640	COG3314	Sporulation integral membrane protein YlbJ
IM743_RS07645	COG1752	Esterase of the alpha-beta hydrolase superfamily
IM743_RS07650	COG3480	Lon protease (S16) C-terminal proteolytic domain
IM743_RS07655	COG1323	Belongs to the UPF0348 family
IM743_RS07665	COG1399	metal-binding, possibly nucleic acid-binding protein
IM743_RS07680	COG0454	-acetyltransferase
IM743_RS07685	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IM743_RS07690	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IM743_RS07695	COG2001	Belongs to the MraZ family
IM743_RS07700	COG0275	rRNA processing
IM743_RS07705	COG4839	cell division protein FtsL
IM743_RS07710	COG0768	penicillin binding
IM743_RS07720	COG0768	penicillin binding
IM743_RS07725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IM743_RS07730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM743_RS07735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM743_RS07740	COG0772	Belongs to the SEDS family
IM743_RS07745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM743_RS07750	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IM743_RS07755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IM743_RS07760	COG3879	Bacterial protein of unknown function (DUF881)
IM743_RS07765	COG3879	Bacterial protein of unknown function (DUF881)
IM743_RS07770	COG3856	small basic protein
IM743_RS07775	COG0849	cell division
IM743_RS07780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IM743_RS07785	COG1404	Belongs to the peptidase S8 family
IM743_RS07785	COG4412	M6 family metalloprotease domain protein
IM743_RS07795	COG1191	sigma factor activity
IM743_RS07800	COG1191	sigma factor activity
IM743_RS07805	COG1119	ATPase activity
IM743_RS07810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM743_RS07815	COG1873	PFAM PRC-barrel domain
IM743_RS07820	COG1496	oxidoreductase activity
IM743_RS07825	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IM743_RS07830	COG1799	cell septum assembly
IM743_RS07835	COG0762	integral membrane protein
IM743_RS07840	COG2302	S4 RNA-binding domain
IM743_RS07845	COG3599	regulation of cell shape
IM743_RS07850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IM743_RS07855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM743_RS07860	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IM743_RS07865	COG0564	pseudouridine synthase activity
IM743_RS07870	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IM743_RS07875	COG2233	PERMEase
IM743_RS07880	COG0540	Belongs to the ATCase OTCase family
IM743_RS07885	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM743_RS07890	COG0505	Belongs to the CarA family
IM743_RS07895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IM743_RS07900	COG0543	2 iron, 2 sulfur cluster binding
IM743_RS07905	COG0167	dihydroorotate dehydrogenase activity
IM743_RS07910	COG0284	orotidine-5'-phosphate decarboxylase activity
IM743_RS07915	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IM743_RS07920	COG0175	sulfate reduction
IM743_RS07925	COG0306	phosphate transporter
IM743_RS07930	COG2046	Belongs to the sulfate adenylyltransferase family
IM743_RS07935	COG0529	Catalyzes the synthesis of activated sulfate
IM743_RS07940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IM743_RS07945	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
IM743_RS07950	COG1648	precorrin-2 dehydrogenase activity
IM743_RS07955	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IM743_RS07960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IM743_RS07965	COG1561	YicC-like family, N-terminal region
IM743_RS07975	COG0194	GDP metabolic process
IM743_RS07980	COG1758	RNA polymerase activity
IM743_RS07985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IM743_RS07990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IM743_RS07995	COG0242	peptide deformylase activity
IM743_RS08000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IM743_RS08005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IM743_RS08005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM743_RS08010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IM743_RS08015	COG0631	protein serine/threonine phosphatase activity
IM743_RS08020	COG2815	serine threonine protein kinase
IM743_RS08020	COG0515	serine threonine protein kinase
IM743_RS08025	COG1162	GTPase activity
IM743_RS08030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM743_RS08035	COG1564	THIamine pyrophosphokinase
IM743_RS08045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IM743_RS08050	COG1302	Protein conserved in bacteria
IM743_RS08055	COG1461	Dihydroxyacetone kinase
IM743_RS08060	COG1760	l-serine dehydratase
IM743_RS08065	COG1760	l-serine dehydratase
IM743_RS08070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IM743_RS08075	COG2050	protein possibly involved in aromatic compounds catabolism
IM743_RS08075	COG1349	DNA-binding transcription factor activity
IM743_RS08080	COG0416	fatty acid biosynthetic process
IM743_RS08085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM743_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS08100	COG0571	ribonuclease III activity
IM743_RS08105	COG1196	nuclear chromosome segregation
IM743_RS08110	COG0552	protein localization to endoplasmic reticulum
IM743_RS08120	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IM743_RS08125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IM743_RS08130	COG0228	four-way junction DNA binding
IM743_RS08135	COG1837	Belongs to the UPF0109 family
IM743_RS08145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IM743_RS08150	COG0336	Belongs to the RNA methyltransferase TrmD family
IM743_RS08155	COG0335	large ribosomal subunit rRNA binding
IM743_RS08160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IM743_RS08165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM743_RS08175	COG2257	FlhB HrpN YscU SpaS Family
IM743_RS08180	COG0045	succinate-CoA ligase (ADP-forming) activity
IM743_RS08185	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IM743_RS08190	COG0758	DNA mediated transformation
IM743_RS08195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IM743_RS08200	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IM743_RS08205	COG4974	Belongs to the 'phage' integrase family
IM743_RS08210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IM743_RS08215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IM743_RS08220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IM743_RS08225	COG1815	bacterial-type flagellum-dependent cell motility
IM743_RS08230	COG1558	bacterial-type flagellum-dependent cell motility
IM743_RS08235	COG1677	Flagellar hook-basal body complex protein FliE
IM743_RS08240	COG1766	The M ring may be actively involved in energy transduction
IM743_RS08245	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM743_RS08250	COG1317	bacterial-type flagellum organization
IM743_RS08255	COG1157	protein secretion by the type III secretion system
IM743_RS08260	COG2882	bacterial-type flagellum organization
IM743_RS08265	COG3334	PFAM MgtE intracellular
IM743_RS08270	COG3144	bacterial-type flagellum assembly
IM743_RS08275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IM743_RS08280	COG4786	Flagellar basal body rod
IM743_RS08285	COG1582	Flagellar protein (FlbD)
IM743_RS08290	COG1580	Controls the rotational direction of flagella during chemotaxis
IM743_RS08295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM743_RS08300	COG1776	CheC inhibitor of MCP methylation
IM743_RS08300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IM743_RS08305	COG2201	protein-glutamate methylesterase activity
IM743_RS08310	COG3190	flagellar
IM743_RS08315	COG1338	Plays a role in the flagellum-specific transport system
IM743_RS08320	COG1987	bacterial-type flagellum assembly
IM743_RS08325	COG1684	flagellar biosynthetic protein fliR
IM743_RS08330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IM743_RS08335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IM743_RS08340	COG1419	protein localization to endoplasmic reticulum
IM743_RS08345	COG0455	bacterial-type flagellum organization
IM743_RS08350	COG2201	protein-glutamate methylesterase activity
IM743_RS08355	COG2198	Histidine kinase
IM743_RS08355	COG0643	Histidine kinase
IM743_RS08360	COG0835	chemotaxis
IM743_RS08365	COG1776	CheC inhibitor of MCP methylation
IM743_RS08370	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IM743_RS08375	COG1191	sigma factor activity
IM743_RS08385	COG0052	Belongs to the universal ribosomal protein uS2 family
IM743_RS08390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IM743_RS08395	COG0528	UMP kinase activity
IM743_RS08400	COG0233	cytoplasmic translational termination
IM743_RS08405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IM743_RS08410	COG4589	Belongs to the CDS family
IM743_RS08415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IM743_RS08420	COG0750	zinc metalloprotease
IM743_RS08425	COG0442	prolyl-tRNA aminoacylation
IM743_RS08430	COG2176	DNA-directed DNA polymerase activity
IM743_RS08435	COG0779	Required for maturation of 30S ribosomal subunits
IM743_RS08440	COG0195	Participates in both transcription termination and antitermination
IM743_RS08445	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IM743_RS08450	COG1358	cellular component organization or biogenesis
IM743_RS08455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IM743_RS08460	COG1550	Protein conserved in bacteria
IM743_RS08465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IM743_RS08470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IM743_RS08475	COG0196	riboflavin kinase activity
IM743_RS08485	COG1185	polyribonucleotide nucleotidyltransferase activity
IM743_RS08490	COG0726	polysaccharide deacetylase
IM743_RS08495	COG0612	Peptidase, M16
IM743_RS08500	COG1873	PFAM PRC-barrel domain
IM743_RS08505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM743_RS08510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IM743_RS08515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IM743_RS08520	COG0527	aspartate kinase activity
IM743_RS08525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IM743_RS08530	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IM743_RS08535	COG0740	serine-type endopeptidase activity
IM743_RS08545	COG4980	gas vesicle protein
IM743_RS08545	COG1674	ftsk spoiiie
IM743_RS08550	COG2188	Transcriptional regulator
IM743_RS08555	COG2814	Major facilitator Superfamily
IM743_RS08560	COG0612	Peptidase, M16
IM743_RS08565	COG0612	Peptidase, M16
IM743_RS08570	COG0300	oxidoreductase activity
IM743_RS08585	COG1426	Protein conserved in bacteria
IM743_RS08590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IM743_RS08595	COG1546	Belongs to the CinA family
IM743_RS08595	COG1058	Belongs to the CinA family
IM743_RS08600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IM743_RS08605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM743_RS08610	COG1418	mRNA catabolic process
IM743_RS08615	COG1692	metallophosphoesterase
IM743_RS08620	COG2359	stage V sporulation protein S
IM743_RS08625	COG1063	alcohol dehydrogenase
IM743_RS08630	COG0156	8-amino-7-oxononanoate synthase activity
IM743_RS08635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM743_RS08640	COG4550	Control of competence regulator ComK, YlbF/YmcA
IM743_RS08650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IM743_RS08655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IM743_RS08690	COG3226	Transcriptional regulator
IM743_RS08695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS08700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM743_RS08705	COG3321	synthase
IM743_RS08710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IM743_RS08710	COG2070	2-Nitropropane dioxygenase
IM743_RS08715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM743_RS08720	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IM743_RS08725	COG3425	synthase
IM743_RS08730	COG1024	Enoyl-CoA hydratase
IM743_RS08735	COG1024	Enoyl-CoA hydratase
IM743_RS08740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS08740	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS08740	COG3321	synthase
IM743_RS08740	COG0300	oxidoreductase activity
IM743_RS08745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM743_RS08745	COG4221	oxidoreductase activity
IM743_RS08745	COG3321	synthase
IM743_RS08745	COG0300	oxidoreductase activity
IM743_RS08750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS08750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS08750	COG3321	synthase
IM743_RS08750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM743_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS08755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS08755	COG4221	oxidoreductase activity
IM743_RS08755	COG3321	synthase
IM743_RS08760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IM743_RS08760	COG3321	synthase
IM743_RS08760	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IM743_RS08760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM743_RS08765	COG2124	cytochrome p450
IM743_RS08775	COG1404	Belongs to the peptidase S8 family
IM743_RS08780	COG4195	phage-related replication protein
IM743_RS08785	COG1764	response to oxidative stress
IM743_RS08810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IM743_RS08815	COG1923	regulation of RNA biosynthetic process
IM743_RS08835	COG1780	Probably involved in ribonucleotide reductase function
IM743_RS08840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM743_RS08845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IM743_RS08850	COG4112	unkown
IM743_RS08855	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM743_RS08860	COG0464	growth
IM743_RS08865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IM743_RS08870	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
IM743_RS08875	COG0789	Transcriptional regulator
IM743_RS08880	COG0174	glutamine synthetase
IM743_RS08905	COG1136	(ABC) transporter
IM743_RS08905	COG0577	efflux transmembrane transporter activity
IM743_RS08935	COG4282	regulation of fungal-type cell wall biogenesis
IM743_RS08940	COG5444	nuclease activity
IM743_RS08955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS08995	COG5632	N-Acetylmuramoyl-L-alanine amidase
IM743_RS09015	COG5444	nuclease activity
IM743_RS09035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM743_RS09040	COG2273	Hydrolase Family 16
IM743_RS09055	COG0457	Tetratricopeptide repeat
IM743_RS09100	COG0726	polysaccharide deacetylase
IM743_RS09130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IM743_RS09135	COG2720	vancomycin resistance protein
IM743_RS09140	COG3739	integral membrane protein
IM743_RS09145	COG3655	Transcriptional regulator
IM743_RS09155	COG2135	peptidase activity
IM743_RS09160	COG5434	Belongs to the glycosyl hydrolase 28 family
IM743_RS09180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IM743_RS09190	COG3832	glyoxalase III activity
IM743_RS09220	COG4195	phage-related replication protein
IM743_RS09240	COG0346	lactoylglutathione lyase activity
IM743_RS09250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IM743_RS09255	COG1388	LysM domain
IM743_RS09260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IM743_RS09265	COG4224	UPF0291 protein
IM743_RS09270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IM743_RS09280	COG3763	UPF0154 protein
IM743_RS09290	COG0785	Cytochrome C biogenesis protein
IM743_RS09295	COG2201	protein-glutamate methylesterase activity
IM743_RS09300	COG4846	Membrane protein involved in cytochrome C biogenesis
IM743_RS09310	COG0071	Belongs to the small heat shock protein (HSP20) family
IM743_RS09325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IM743_RS09330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS09350	COG0824	Thioesterase
IM743_RS09360	COG4841	protein insertion into membrane
IM743_RS09365	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IM743_RS09370	COG1832	CoA-binding protein
IM743_RS09375	COG0187	DNA topoisomerase II activity
IM743_RS09380	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IM743_RS09390	COG1115	amino acid carrier protein
IM743_RS09395	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IM743_RS09420	COG3507	Belongs to the glycosyl hydrolase 43 family
IM743_RS09435	COG2246	polysaccharide biosynthetic process
IM743_RS09440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM743_RS09445	COG0586	Pfam SNARE associated Golgi protein
IM743_RS09450	COG2404	hydrolase activity, acting on ester bonds
IM743_RS09455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM743_RS09460	COG1024	Enoyl-CoA hydratase
IM743_RS09465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM743_RS09470	COG0511	ligase activity, forming carbon-carbon bonds
IM743_RS09475	COG0439	Biotin carboxylase
IM743_RS09480	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS09485	COG1960	acyl-CoA dehydrogenase activity
IM743_RS09495	COG1649	PFAM Uncharacterised BCR, COG1649
IM743_RS09505	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IM743_RS09505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS09510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS09515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS09520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS09525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS09530	COG2027	D-alanyl-D-alanine carboxypeptidase
IM743_RS09535	COG2017	converts alpha-aldose to the beta-anomer
IM743_RS09540	COG0534	Mate efflux family protein
IM743_RS09555	COG0582	viral genome integration into host DNA
IM743_RS09560	COG0166	Belongs to the GPI family
IM743_RS09565	COG0405	Gamma-glutamyltransferase
IM743_RS09570	COG0583	DNA-binding transcription factor activity
IM743_RS09575	COG0604	alcohol dehydrogenase
IM743_RS09580	COG0493	'glutamate synthase
IM743_RS09585	COG0069	glutamate synthase activity
IM743_RS09585	COG0067	glutamate synthase
IM743_RS09585	COG0070	glutamate synthase
IM743_RS09590	COG0583	DNA-binding transcription factor activity
IM743_RS09595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IM743_RS09615	COG0300	oxidoreductase activity
IM743_RS09620	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IM743_RS09630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS09645	COG1131	(ABC) transporter
IM743_RS09655	COG2814	Major facilitator Superfamily
IM743_RS09660	COG1070	Carbohydrate kinase
IM743_RS09665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM743_RS09670	COG0243	molybdopterin cofactor binding
IM743_RS09680	COG4305	rare lipoprotein A
IM743_RS09685	COG3619	membrane
IM743_RS09695	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS09745	COG2814	Major facilitator Superfamily
IM743_RS09750	COG1525	nuclease
IM743_RS09755	COG1231	oxidoreductase activity
IM743_RS09760	COG1070	Carbohydrate kinase
IM743_RS09775	COG3507	Belongs to the glycosyl hydrolase 43 family
IM743_RS09780	COG2211	Major facilitator Superfamily
IM743_RS09800	COG3397	chitin binding
IM743_RS09805	COG2318	DinB family
IM743_RS09810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IM743_RS09845	COG0457	Tetratricopeptide repeat
IM743_RS09860	COG3848	Pyruvate phosphate dikinase
IM743_RS09860	COG0574	Belongs to the PEP-utilizing enzyme family
IM743_RS09870	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS09875	COG1733	regulation of RNA biosynthetic process
IM743_RS09880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM743_RS09885	COG0662	Cupin 2, conserved barrel domain protein
IM743_RS09885	COG2207	Transcriptional regulator
IM743_RS09890	COG0456	acetyltransferase
IM743_RS09895	COG1309	transcriptional regulator
IM743_RS09900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS09905	COG3708	Transcriptional regulator
IM743_RS09910	COG2378	regulation of single-species biofilm formation
IM743_RS09920	COG0640	Transcriptional regulator
IM743_RS09925	COG0741	lytic transglycosylase activity
IM743_RS09930	COG2322	membrane
IM743_RS09945	COG1619	proteins homologs of microcin C7 resistance protein MccF
IM743_RS09950	COG3239	Fatty acid desaturase
IM743_RS09955	COG4585	Histidine kinase
IM743_RS09960	COG2197	response regulator
IM743_RS09970	COG1388	LysM domain
IM743_RS09970	COG3584	3D domain protein
IM743_RS09975	COG0514	ATP-dependent DNA helicase (RecQ)
IM743_RS09985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM743_RS09990	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM743_RS10005	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS10010	COG1657	PFAM Prenyltransferase squalene oxidase
IM743_RS10015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM743_RS10020	COG0733	neurotransmitter:sodium symporter activity
IM743_RS10025	COG0385	Bile acid
IM743_RS10030	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM743_RS10035	COG0567	Dehydrogenase, E1 component
IM743_RS10040	COG4548	von Willebrand factor, type A
IM743_RS10045	COG0714	Associated with various cellular activities
IM743_RS10050	COG2032	superoxide dismutase activity
IM743_RS10055	COG0791	NLP P60 protein
IM743_RS10055	COG1388	LysM domain
IM743_RS10060	COG1819	glycosyl
IM743_RS10065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IM743_RS10070	COG0534	Mate efflux family protein
IM743_RS10075	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS10080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM743_RS10085	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM743_RS10095	COG2962	Rard protein
IM743_RS10115	COG1942	4-Oxalocrotonate Tautomerase
IM743_RS10125	COG1733	regulation of RNA biosynthetic process
IM743_RS10130	COG0778	Nitroreductase
IM743_RS10135	COG0400	carboxylic ester hydrolase activity
IM743_RS10140	COG0346	lactoylglutathione lyase activity
IM743_RS10150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM743_RS10155	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS10155	COG0793	Belongs to the peptidase S41A family
IM743_RS10160	COG2226	methyltransferase
IM743_RS10170	COG1876	peptidase activity
IM743_RS10175	COG0813	purine-nucleoside phosphorylase activity
IM743_RS10190	COG0671	phosphoesterase, PA-phosphatase related
IM743_RS10210	COG4479	Belongs to the UPF0346 family
IM743_RS10220	COG1509	lysine 2,3-aminomutase activity
IM743_RS10225	COG0456	acetyltransferase
IM743_RS10230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM743_RS10235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IM743_RS10240	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IM743_RS10245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM743_RS10255	COG0456	acetyltransferase
IM743_RS10260	COG0463	Glycosyl transferase, family 2
IM743_RS10275	COG4641	Protein conserved in bacteria
IM743_RS10285	COG1086	Polysaccharide biosynthesis protein
IM743_RS10295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IM743_RS10300	COG1846	Transcriptional regulator
IM743_RS10305	COG0534	Mate efflux family protein
IM743_RS10315	COG4698	Protein conserved in bacteria
IM743_RS10320	COG2755	lipolytic protein G-D-S-L family
IM743_RS10325	COG1999	signal sequence binding
IM743_RS10335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IM743_RS10340	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IM743_RS10345	COG1272	protein, Hemolysin III
IM743_RS10350	COG0204	Acyl-transferase
IM743_RS10355	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM743_RS10365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IM743_RS10375	COG2136	Putative SAM-dependent methyltransferase
IM743_RS10375	COG2521	methyltransferase
IM743_RS10385	COG0129	dihydroxy-acid dehydratase activity
IM743_RS10390	COG1413	lyase activity
IM743_RS10395	COG1418	mRNA catabolic process
IM743_RS10400	COG0386	Belongs to the glutathione peroxidase family
IM743_RS10405	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IM743_RS10410	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IM743_RS10420	COG1278	Cold shock
IM743_RS10440	COG0328	RNA-DNA hybrid ribonuclease activity
IM743_RS10445	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IM743_RS10450	COG0328	RNA-DNA hybrid ribonuclease activity
IM743_RS10460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM743_RS10475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IM743_RS10485	COG1755	Isoprenylcysteine carboxyl methyltransferase
IM743_RS10490	COG3424	synthase
IM743_RS10495	COG2233	PERMEase
IM743_RS10500	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM743_RS10505	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IM743_RS10515	COG0800	Aldolase
IM743_RS10520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM743_RS10525	COG1609	Transcriptional regulator
IM743_RS10530	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IM743_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS10540	COG1199	ATP-dependent helicase activity
IM743_RS10555	COG0116	Belongs to the methyltransferase superfamily
IM743_RS10570	COG4474	Belongs to the UPF0398 family
IM743_RS10585	COG3359	exonuclease
IM743_RS10590	COG1111	helicase
IM743_RS10590	COG1205	dead DEAH box helicase
IM743_RS10595	COG2190	(PTS) system
IM743_RS10600	COG0071	Belongs to the small heat shock protein (HSP20) family
IM743_RS10640	COG3331	DNA recombination
IM743_RS10645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM743_RS10645	COG4499	WXG100 protein secretion system (Wss), protein YukC
IM743_RS10655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IM743_RS10660	COG3935	DnaD domain protein
IM743_RS10665	COG0017	Asparaginyl-tRNA synthetase
IM743_RS10670	COG0436	Aminotransferase
IM743_RS10675	COG5353	protein conserved in bacteria
IM743_RS10685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IM743_RS10685	COG1199	ATP-dependent helicase activity
IM743_RS10690	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IM743_RS10695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IM743_RS10700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IM743_RS10705	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IM743_RS10705	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IM743_RS10710	COG0617	tRNA 3'-terminal CCA addition
IM743_RS10715	COG0438	transferase activity, transferring glycosyl groups
IM743_RS10720	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM743_RS10725	COG1803	Methylglyoxal synthase
IM743_RS10730	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IM743_RS10735	COG1694	Mazg nucleotide pyrophosphohydrolase
IM743_RS10740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS10750	COG4347	Protein of unknown function (DUF1405)
IM743_RS10755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM743_RS10755	COG2010	Cytochrome c
IM743_RS10760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IM743_RS10765	COG0723	plastoquinol--plastocyanin reductase activity
IM743_RS10775	COG5582	Belongs to the UPF0302 family
IM743_RS10780	COG0457	Tetratricopeptide repeat
IM743_RS10785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IM743_RS10790	COG0287	Prephenate dehydrogenase
IM743_RS10795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IM743_RS10800	COG0159	tryptophan synthase activity
IM743_RS10805	COG0133	tryptophan synthase activity
IM743_RS10810	COG0135	phosphoribosylanthranilate isomerase activity
IM743_RS10820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IM743_RS10825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IM743_RS10830	COG4401	Chorismate mutase type I
IM743_RS10835	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IM743_RS10840	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IM743_RS10845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IM743_RS10850	COG0105	UTP biosynthetic process
IM743_RS10855	COG0142	geranyltranstransferase activity
IM743_RS10860	COG2226	methyltransferase
IM743_RS10865	COG0142	geranyltranstransferase activity
IM743_RS10875	COG0302	gtp cyclohydrolase
IM743_RS10880	COG0776	regulation of translation
IM743_RS10885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IM743_RS10900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IM743_RS10905	COG1160	GTP binding
IM743_RS10930	COG1304	FMN binding
IM743_RS10935	COG0539	negative regulation of cytoplasmic translation
IM743_RS10940	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IM743_RS10950	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IM743_RS10955	COG2959	enzyme of heme biosynthesis
IM743_RS10960	COG3773	Cell wall hydrolase
IM743_RS10960	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS10965	COG2339	peptidase activity
IM743_RS10975	COG0492	ferredoxin-NADP+ reductase activity
IM743_RS10980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IM743_RS10985	COG4862	establishment of competence for transformation
IM743_RS10990	COG1408	metallophosphoesterase
IM743_RS11000	COG1388	LysM domain
IM743_RS11005	COG1266	CAAX protease self-immunity
IM743_RS11010	COG0514	ATP-dependent DNA helicase (RecQ)
IM743_RS11015	COG4955	Helix-turn-helix domain
IM743_RS11020	COG1141	Ferredoxin
IM743_RS11025	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IM743_RS11030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IM743_RS11035	COG0710	3-dehydroquinate dehydratase activity
IM743_RS11045	COG1595	DNA-templated transcription, initiation
IM743_RS11050	COG5002	protein histidine kinase activity
IM743_RS11055	COG0745	RESPONSE REGULATOR receiver
IM743_RS11060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM743_RS11065	COG1333	cytochrome c biogenesis protein
IM743_RS11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS11075	COG1187	pseudouridine synthase activity
IM743_RS11080	COG0700	Nucleoside recognition
IM743_RS11085	COG2715	membrane protein required for spore maturation
IM743_RS11090	COG1686	Belongs to the peptidase S11 family
IM743_RS11100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IM743_RS11105	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IM743_RS11115	COG1547	Domain of unknown function (DUF309)
IM743_RS11120	COG0456	acetyltransferase
IM743_RS11125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IM743_RS11130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM743_RS11130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IM743_RS11135	COG0307	riboflavin synthase, alpha
IM743_RS11140	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM743_RS11140	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IM743_RS11150	COG0681	Belongs to the peptidase S26 family
IM743_RS11155	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
IM743_RS11160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IM743_RS11165	COG4086	secreted protein
IM743_RS11170	COG0019	diaminopimelate decarboxylase activity
IM743_RS11175	COG0697	spore germination
IM743_RS11190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IM743_RS11210	COG1191	sigma factor activity
IM743_RS11215	COG2172	sigma factor antagonist activity
IM743_RS11220	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS11225	COG1686	Belongs to the peptidase S11 family
IM743_RS11230	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IM743_RS11235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IM743_RS11240	COG4974	Belongs to the 'phage' integrase family
IM743_RS11250	COG0735	belongs to the Fur family
IM743_RS11255	COG1300	Membrane
IM743_RS11265	COG0281	malic enzyme
IM743_RS11270	COG1757	Na H antiporter
IM743_RS11275	COG1027	Aspartate ammonia-lyase
IM743_RS11280	COG0252	asparaginase activity
IM743_RS11285	COG1396	sequence-specific DNA binding
IM743_RS11290	COG1379	DNA repair
IM743_RS11295	COG0494	nUDIX hydrolase
IM743_RS11305	COG0667	Aldo Keto reductase
IM743_RS11315	COG1073	alpha beta
IM743_RS11325	COG4918	Iron-sulphur cluster biosynthesis
IM743_RS11330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IM743_RS11330	COG0456	acetyltransferase
IM743_RS11335	COG2329	Antibiotic biosynthesis monooxygenase
IM743_RS11340	COG0456	acetyltransferase
IM743_RS11350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM743_RS11360	COG2211	Major facilitator Superfamily
IM743_RS11375	COG1072	(Pantothenic acid kinase))
IM743_RS11380	COG3048	D-serine ammonia-lyase activity
IM743_RS11385	COG0300	oxidoreductase activity
IM743_RS11390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS11395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM743_RS11400	COG4187	Peptidase family M20/M25/M40
IM743_RS11405	COG1902	pentaerythritol trinitrate reductase activity
IM743_RS11410	COG0596	Alpha beta hydrolase
IM743_RS11420	COG1234	tRNA 3'-trailer cleavage
IM743_RS11425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IM743_RS11435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM743_RS11440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IM743_RS11450	COG0706	membrane insertase activity
IM743_RS11455	COG3361	conserved protein (COG2071)
IM743_RS11460	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM743_RS11465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IM743_RS11470	COG0346	lactoylglutathione lyase activity
IM743_RS11480	COG1376	ErfK ybiS ycfS ynhG family protein
IM743_RS11485	COG4129	membrane
IM743_RS11490	COG1126	abc transporter atp-binding protein
IM743_RS11495	COG0765	amino acid transport
IM743_RS11500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM743_RS11510	COG1597	lipid kinase activity
IM743_RS11515	COG2814	Major facilitator Superfamily
IM743_RS11520	COG0789	Transcriptional regulator
IM743_RS11520	COG4978	Transcriptional regulator
IM743_RS11525	COG0508	dehydrogenase complex catalyzes the overall conversion of
IM743_RS11530	COG0022	dehydrogenase e1 component
IM743_RS11535	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IM743_RS11540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IM743_RS11545	COG3426	butyrate kinase activity
IM743_RS11550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IM743_RS11555	COG0280	phosphate acetyltransferase
IM743_RS11560	COG3829	transcription factor binding
IM743_RS11560	COG3290	protein histidine kinase activity
IM743_RS11570	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IM743_RS11575	COG2079	MmgE PrpD family protein
IM743_RS11580	COG0372	Belongs to the citrate synthase family
IM743_RS11585	COG1960	acyl-CoA dehydrogenase activity
IM743_RS11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM743_RS11595	COG0183	Belongs to the thiolase family
IM743_RS11600	COG0584	glycerophosphoryl diester phosphodiesterase
IM743_RS11605	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM743_RS11620	COG1902	pentaerythritol trinitrate reductase activity
IM743_RS11625	COG0745	RESPONSE REGULATOR receiver
IM743_RS11630	COG0750	zinc metalloprotease
IM743_RS11635	COG0497	DNA recombination
IM743_RS11640	COG1438	arginine binding
IM743_RS11645	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IM743_RS11650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IM743_RS11655	COG0142	geranyltranstransferase activity
IM743_RS11660	COG1722	exodeoxyribonuclease VII activity
IM743_RS11665	COG1570	exodeoxyribonuclease VII activity
IM743_RS11670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IM743_RS11675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IM743_RS11680	COG1302	Protein conserved in bacteria
IM743_RS11685	COG0439	Biotin carboxylase
IM743_RS11690	COG0511	ligase activity, forming carbon-carbon bonds
IM743_RS11730	COG3854	ATPases associated with a variety of cellular activities
IM743_RS11740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IM743_RS11745	COG0006	proline dipeptidase activity
IM743_RS11750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IM743_RS11760	COG3872	metal-dependent enzyme
IM743_RS11770	COG1752	Esterase of the alpha-beta hydrolase superfamily
IM743_RS11775	COG1321	iron dependent repressor
IM743_RS11780	COG0095	Lipoate-protein ligase
IM743_RS11785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM743_RS11790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM743_RS11795	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IM743_RS11800	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IM743_RS11805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM743_RS11820	COG1396	sequence-specific DNA binding
IM743_RS11830	COG0681	Belongs to the peptidase S26 family
IM743_RS11855	COG4940	Competence protein ComGF
IM743_RS11865	COG4970	Tfp pilus assembly protein FimT
IM743_RS11870	COG4537	Required for transformation and DNA binding
IM743_RS11875	COG1459	type II secretion system
IM743_RS11880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IM743_RS11885	COG0517	IMP dehydrogenase activity
IM743_RS11890	COG0598	Magnesium transport protein CorA
IM743_RS11895	COG1253	flavin adenine dinucleotide binding
IM743_RS11900	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS11910	COG1393	Belongs to the ArsC family
IM743_RS11920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS11930	COG0011	TIGRFAM Protein of
IM743_RS11940	COG2866	Carboxypeptidase
IM743_RS11945	COG1368	sulfuric ester hydrolase activity
IM743_RS11950	COG1940	carbohydrate kinase activity
IM743_RS11955	COG4483	Protein conserved in bacteria
IM743_RS11960	COG0705	Rhomboid family
IM743_RS11960	COG0457	Tetratricopeptide repeat
IM743_RS11970	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IM743_RS11980	COG0438	transferase activity, transferring glycosyl groups
IM743_RS11995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM743_RS12005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM743_RS12010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IM743_RS12015	COG0581	inorganic phosphate transmembrane transporter activity
IM743_RS12020	COG0573	inorganic phosphate transmembrane transporter activity
IM743_RS12025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IM743_RS12030	COG0768	penicillin binding
IM743_RS12035	COG0477	Major facilitator Superfamily
IM743_RS12040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IM743_RS12045	COG2839	Protein conserved in bacteria
IM743_RS12050	COG5521	maltodextrose utilization protein MalA
IM743_RS12065	COG1388	LysM domain
IM743_RS12070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IM743_RS12075	COG4709	membrane
IM743_RS12080	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
IM743_RS12085	COG0735	belongs to the Fur family
IM743_RS12090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS12100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IM743_RS12105	COG0513	Belongs to the DEAD box helicase family
IM743_RS12115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IM743_RS12120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IM743_RS12125	COG2384	SAM-dependent methyltransferase
IM743_RS12130	COG2010	Cytochrome c
IM743_RS12135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IM743_RS12140	COG0358	DNA primase activity
IM743_RS12145	COG1671	Belongs to the UPF0178 family
IM743_RS12150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IM743_RS12155	COG0517	IMP dehydrogenase activity
IM743_RS12160	COG0751	glycine-tRNA ligase activity
IM743_RS12165	COG0752	glycyl-tRNA synthetase alpha subunit
IM743_RS12170	COG1381	Involved in DNA repair and RecF pathway recombination
IM743_RS12180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IM743_RS12185	COG0295	cytidine deaminase activity
IM743_RS12190	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IM743_RS12195	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IM743_RS12200	COG1480	7TM receptor with intracellular HD hydrolase
IM743_RS12205	COG1702	phosphate starvation-inducible protein PhoH
IM743_RS12210	COG0561	phosphatase activity
IM743_RS12225	COG4864	UPF0365 protein
IM743_RS12230	COG1030	water channel activity
IM743_RS12235	COG1610	YqeY-like protein
IM743_RS12245	COG1283	sodium-dependent phosphate transmembrane transporter activity
IM743_RS12250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IM743_RS12255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IM743_RS12260	COG2264	protein methyltransferase activity
IM743_RS12265	COG0484	heat shock protein binding
IM743_RS12275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IM743_RS12280	COG1420	regulation of RNA biosynthetic process
IM743_RS12285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IM743_RS12290	COG0481	GTPase activity
IM743_RS12300	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM743_RS12305	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IM743_RS12315	COG1466	dna polymerase III delta subunit
IM743_RS12330	COG0658	competence protein
IM743_RS12330	COG2333	competence protein COMEC
IM743_RS12335	COG2131	deaminase
IM743_RS12340	COG1596	polysaccharide export
IM743_RS12340	COG1555	photosystem II stabilization
IM743_RS12345	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IM743_RS12350	COG2226	methyltransferase
IM743_RS12355	COG0799	negative regulation of ribosome biogenesis
IM743_RS12360	COG1713	HD superfamily hydrolase involved in NAD metabolism
IM743_RS12365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IM743_RS12370	COG1534	Rna-binding protein
IM743_RS12375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IM743_RS12380	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IM743_RS12385	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IM743_RS12395	COG2755	lipolytic protein G-D-S-L family
IM743_RS12400	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS12400	COG5632	N-Acetylmuramoyl-L-alanine amidase
IM743_RS12405	COG0398	Pfam SNARE associated Golgi protein
IM743_RS12410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IM743_RS12420	COG3209	COG3209 Rhs family protein
IM743_RS12435	COG3223	Belongs to the PsiE family
IM743_RS12440	COG0642	Histidine kinase
IM743_RS12440	COG5002	protein histidine kinase activity
IM743_RS12445	COG0745	RESPONSE REGULATOR receiver
IM743_RS12450	COG2311	Membrane
IM743_RS12455	COG0454	-acetyltransferase
IM743_RS12460	COG0457	Tetratricopeptide repeat
IM743_RS12505	COG3443	Belongs to the bacterial solute-binding protein 9 family
IM743_RS12510	COG1595	DNA-templated transcription, initiation
IM743_RS12515	COG2851	Citrate transporter
IM743_RS12520	COG0583	DNA-binding transcription factor activity
IM743_RS12525	COG2828	Protein conserved in bacteria
IM743_RS12530	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS12535	COG5566	PFAM Mor transcription activator
IM743_RS12540	COG0596	Alpha beta hydrolase
IM743_RS12545	COG0697	spore germination
IM743_RS12550	COG0110	maltose O-acetyltransferase activity
IM743_RS12555	COG4991	sh3 domain protein
IM743_RS12560	COG4991	sh3 domain protein
IM743_RS12575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS12585	COG0693	protein deglycase activity
IM743_RS12590	COG1621	beta-fructofuranosidase activity
IM743_RS12595	COG3716	PTS system mannose fructose sorbose family IID component
IM743_RS12600	COG3715	PTS system
IM743_RS12605	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS12610	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS12615	COG3933	PFAM sigma-54 factor interaction domain-containing protein
IM743_RS12615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IM743_RS12620	COG1113	amino acid transport
IM743_RS12625	COG1280	lysine exporter protein (LysE YggA)
IM743_RS12630	COG1378	Sugar-specific transcriptional regulator TrmB
IM743_RS12635	COG1595	DNA-templated transcription, initiation
IM743_RS12645	COG2755	lipolytic protein G-D-S-L family
IM743_RS12645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IM743_RS12660	COG1309	transcriptional regulator
IM743_RS12665	COG2226	methyltransferase
IM743_RS12680	COG2116	formate transmembrane transporter activity
IM743_RS12685	COG5609	conserved protein (DUF2294)
IM743_RS12690	COG3383	formate dehydrogenase (NAD+) activity
IM743_RS12695	COG2427	Protein of unknown function (DUF1641)
IM743_RS12705	COG0626	cystathionine gamma-synthase activity
IM743_RS12710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM743_RS12715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IM743_RS12720	COG2226	methyltransferase
IM743_RS12735	COG0768	penicillin binding
IM743_RS12740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IM743_RS12745	COG0572	uridine kinase
IM743_RS12750	COG0826	peptidase U32
IM743_RS12755	COG0826	peptidase U32
IM743_RS12760	COG4122	O-methyltransferase activity
IM743_RS12765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IM743_RS12770	COG3906	Belongs to the UPF0473 family
IM743_RS12775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IM743_RS12780	COG4472	Bacterial protein of unknown function (DUF965)
IM743_RS12785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IM743_RS12790	COG0628	permease
IM743_RS12795	COG1126	abc transporter atp-binding protein
IM743_RS12800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM743_RS12805	COG0765	amino acid transport
IM743_RS12810	COG0765	amino acid transport
IM743_RS12825	COG3881	PFAM PRC-barrel domain
IM743_RS12830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IM743_RS12835	COG0457	Tetratricopeptide repeat
IM743_RS12840	COG0482	sulfurtransferase activity
IM743_RS12845	COG1104	cysteine desulfurase activity
IM743_RS12850	COG1959	2 iron, 2 sulfur cluster binding
IM743_RS12855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IM743_RS12860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IM743_RS12870	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IM743_RS12875	COG0124	histidyl-tRNA synthetase
IM743_RS12885	COG3103	Sh3 type 3 domain protein
IM743_RS12885	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM743_RS12885	COG4991	sh3 domain protein
IM743_RS12895	COG1490	D-aminoacyl-tRNA deacylase activity
IM743_RS12900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IM743_RS12905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IM743_RS12910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IM743_RS12910	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IM743_RS12915	COG5416	Lipopolysaccharide assembly protein A domain
IM743_RS12920	COG0490	domain, Protein
IM743_RS12925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM743_RS12925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IM743_RS12935	COG2244	polysaccharide biosynthetic process
IM743_RS12940	COG2323	membrane
IM743_RS12950	COG1862	Preprotein translocase
IM743_RS12955	COG0343	queuine tRNA-ribosyltransferase activity
IM743_RS12960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IM743_RS12970	COG2255	four-way junction helicase activity
IM743_RS12975	COG0632	four-way junction helicase activity
IM743_RS12985	COG2814	Major facilitator Superfamily
IM743_RS12990	COG0673	inositol 2-dehydrogenase activity
IM743_RS12995	COG2112	serine threonine protein kinase
IM743_RS13010	COG1115	amino acid carrier protein
IM743_RS13015	COG0217	transcriptional regulatory protein
IM743_RS13025	COG1388	LysM domain
IM743_RS13030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IM743_RS13035	COG0157	Belongs to the NadC ModD family
IM743_RS13040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IM743_RS13045	COG1104	cysteine desulfurase activity
IM743_RS13050	COG1827	regulation of RNA biosynthetic process
IM743_RS13055	COG0077	Prephenate dehydratase
IM743_RS13060	COG4492	Belongs to the UPF0735 family
IM743_RS13065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IM743_RS13070	COG3290	protein histidine kinase activity
IM743_RS13080	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IM743_RS13085	COG2868	ribosomal protein
IM743_RS13090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IM743_RS13095	COG1994	Peptidase M50
IM743_RS13100	COG0739	heme binding
IM743_RS13105	COG2894	cell division
IM743_RS13110	COG0850	regulation of cytokinetic process
IM743_RS13115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IM743_RS13125	COG1077	Cell shape determining protein MreB Mrl
IM743_RS13130	COG2003	Belongs to the UPF0758 family
IM743_RS13135	COG0424	maF-like protein
IM743_RS13145	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IM743_RS13150	COG0285	dihydrofolate synthase activity
IM743_RS13155	COG0525	valine-tRNA ligase activity
IM743_RS13165	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM743_RS13170	COG1388	LysM domain
IM743_RS13175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IM743_RS13180	COG0113	porphobilinogen synthase activity
IM743_RS13185	COG1587	Uroporphyrinogen-III synthase
IM743_RS13190	COG0181	hydroxymethylbilane synthase activity
IM743_RS13195	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IM743_RS13200	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IM743_RS13210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IM743_RS13215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IM743_RS13220	COG1067	ATP-dependent peptidase activity
IM743_RS13220	COG0470	DNA polymerase III
IM743_RS13225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IM743_RS13230	COG0544	peptidyl-prolyl cis-trans isomerase activity
IM743_RS13235	COG1477	protein flavinylation
IM743_RS13235	COG0457	Tetratricopeptide repeat
IM743_RS13240	COG0066	3-isopropylmalate dehydratase activity
IM743_RS13245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IM743_RS13250	COG0473	3-isopropylmalate dehydrogenase activity
IM743_RS13255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IM743_RS13260	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IM743_RS13265	COG0440	acetolactate synthase activity
IM743_RS13270	COG0028	Belongs to the TPP enzyme family
IM743_RS13280	COG0454	-acetyltransferase
IM743_RS13285	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
IM743_RS13300	COG0622	Phosphoesterase
IM743_RS13305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IM743_RS13310	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IM743_RS13315	COG5401	PFAM Sporulation and spore germination
IM743_RS13320	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IM743_RS13325	COG1846	Transcriptional regulator
IM743_RS13330	COG2197	response regulator
IM743_RS13335	COG0824	Thioesterase
IM743_RS13340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IM743_RS13345	COG1053	succinate dehydrogenase
IM743_RS13350	COG2009	succinate dehydrogenase
IM743_RS13355	COG1719	4-vinyl reductase, 4VR
IM743_RS13360	COG0527	aspartate kinase activity
IM743_RS13370	COG0322	excinuclease ABC activity
IM743_RS13375	COG3118	belongs to the thioredoxin family
IM743_RS13380	COG3534	alpha-L-arabinofuranosidase
IM743_RS13385	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IM743_RS13390	COG2086	electron transfer activity
IM743_RS13395	COG1024	Enoyl-CoA hydratase
IM743_RS13400	COG1309	transcriptional regulator
IM743_RS13405	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS13410	COG3766	membrane
IM743_RS13415	COG1193	negative regulation of DNA recombination
IM743_RS13420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM743_RS13420	COG1796	DNA polymerase
IM743_RS13425	COG1286	toxin biosynthetic process
IM743_RS13430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IM743_RS13435	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IM743_RS13440	COG0072	phenylalanine-tRNA ligase activity
IM743_RS13440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM743_RS13445	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IM743_RS13455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IM743_RS13465	COG3835	regulator
IM743_RS13470	COG0277	FAD linked oxidase domain protein
IM743_RS13475	COG0247	lactate metabolic process
IM743_RS13480	COG0346	lactoylglutathione lyase activity
IM743_RS13485	COG1966	Carbon starvation protein
IM743_RS13500	COG1695	Transcriptional regulator
IM743_RS13505	COG3534	alpha-L-arabinofuranosidase
IM743_RS13510	COG0395	ABC-type sugar transport system, permease component
IM743_RS13515	COG1175	transmembrane transport
IM743_RS13520	COG1653	transport
IM743_RS13525	COG0371	Dehydrogenase
IM743_RS13530	COG0647	UMP catabolic process
IM743_RS13535	COG0235	Class ii aldolase
IM743_RS13540	COG1069	ribulokinase activity
IM743_RS13545	COG2160	L-arabinose isomerase activity
IM743_RS13550	COG3507	Belongs to the glycosyl hydrolase 43 family
IM743_RS13555	COG1363	Peptidase, m42
IM743_RS13565	COG3326	Membrane
IM743_RS13570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IM743_RS13575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IM743_RS13580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IM743_RS13595	COG1346	cytolysis
IM743_RS13600	COG1380	Effector of murein hydrolase LrgA
IM743_RS13605	COG3279	Response regulator of the LytR AlgR family
IM743_RS13610	COG3275	phosphorelay sensor kinase activity
IM743_RS13615	COG1011	Hydrolase
IM743_RS13620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM743_RS13630	COG0398	Pfam SNARE associated Golgi protein
IM743_RS13635	COG1484	DNA-dependent DNA replication
IM743_RS13640	COG3611	Membrane attachment protein
IM743_RS13645	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IM743_RS13650	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IM743_RS13655	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM743_RS13660	COG1733	regulation of RNA biosynthetic process
IM743_RS13665	COG2814	Major facilitator Superfamily
IM743_RS13670	COG0656	L-ascorbic acid biosynthetic process
IM743_RS13675	COG0237	dephospho-CoA kinase activity
IM743_RS13680	COG1971	Probably functions as a manganese efflux pump
IM743_RS13685	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IM743_RS13690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM743_RS13690	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IM743_RS13695	COG5002	protein histidine kinase activity
IM743_RS13700	COG0745	RESPONSE REGULATOR receiver
IM743_RS13705	COG0039	L-malate dehydrogenase activity
IM743_RS13710	COG0538	isocitrate dehydrogenase activity
IM743_RS13715	COG0372	Belongs to the citrate synthase family
IM743_RS13720	COG2707	UPF0756 membrane protein
IM743_RS13725	COG0628	permease
IM743_RS13730	COG3030	protein affecting phage T7 exclusion by the F plasmid
IM743_RS13735	COG0469	pyruvate kinase activity
IM743_RS13740	COG0205	6-phosphofructokinase activity
IM743_RS13745	COG0825	malonyl-CoA metabolic process
IM743_RS13750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IM743_RS13755	COG0281	malic enzyme
IM743_RS13760	COG0587	DNA-directed DNA polymerase activity
IM743_RS13780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IM743_RS13790	COG4109	DRTGG domain
IM743_RS13795	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IM743_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS13805	COG0165	Argininosuccinate lyase
IM743_RS13810	COG0137	argininosuccinate synthase activity
IM743_RS13815	COG0521	Mo-molybdopterin cofactor biosynthetic process
IM743_RS13820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IM743_RS13825	COG0827	DNA restriction-modification system
IM743_RS13830	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IM743_RS13835	COG3874	Sporulation protein YtfJ
IM743_RS13845	COG1714	RDD family
IM743_RS13850	COG0616	signal peptide processing
IM743_RS13855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IM743_RS13860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IM743_RS13865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM743_RS13875	COG0301	tRNA thio-modification
IM743_RS13880	COG1104	cysteine desulfurase activity
IM743_RS13885	COG1114	Component of the transport system for branched-chain amino acids
IM743_RS13890	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IM743_RS13895	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IM743_RS13900	COG1309	transcriptional regulator
IM743_RS13905	COG1956	GAF domain-containing protein
IM743_RS13910	COG2203	Gaf domain
IM743_RS13910	COG2199	diguanylate cyclase activity
IM743_RS13920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM743_RS13925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IM743_RS13930	COG0454	-acetyltransferase
IM743_RS13935	COG0517	IMP dehydrogenase activity
IM743_RS13940	COG0123	including yeast histone deacetylase and acetoin utilization protein
IM743_RS13945	COG1360	Flagellar Motor Protein
IM743_RS13950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IM743_RS13955	COG1609	Transcriptional regulator
IM743_RS13960	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IM743_RS13960	COG1605	Chorismate mutase
IM743_RS13965	COG3118	belongs to the thioredoxin family
IM743_RS13970	COG4980	gas vesicle protein
IM743_RS13975	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IM743_RS13980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IM743_RS13985	COG1674	ftsk spoiiie
IM743_RS13990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IM743_RS13995	COG4848	Belongs to the UPF0354 family
IM743_RS14000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS14015	COG1363	Peptidase, m42
IM743_RS14020	COG5584	Small secreted protein
IM743_RS14025	COG0281	malic enzyme
IM743_RS14030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS14035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IM743_RS14045	COG0510	thiamine kinase activity
IM743_RS14050	COG1523	belongs to the glycosyl hydrolase 13 family
IM743_RS14055	COG1597	lipid kinase activity
IM743_RS14065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IM743_RS14070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IM743_RS14075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM743_RS14080	COG2252	PERMEase
IM743_RS14085	COG4473	ABC transporter
IM743_RS14090	COG1131	(ABC) transporter
IM743_RS14095	COG1349	DNA-binding transcription factor activity
IM743_RS14100	COG1187	pseudouridine synthase activity
IM743_RS14105	COG2244	polysaccharide biosynthetic process
IM743_RS14110	COG2081	HI0933 family
IM743_RS14115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IM743_RS14125	COG5578	integral membrane protein
IM743_RS14130	COG0673	inositol 2-dehydrogenase activity
IM743_RS14135	COG1653	transport
IM743_RS14140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IM743_RS14145	COG4209	transmembrane transport
IM743_RS14150	COG2207	Transcriptional regulator
IM743_RS14155	COG1653	transport
IM743_RS14160	COG0395	ABC-type sugar transport system, permease component
IM743_RS14165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS14170	COG2124	cytochrome p450
IM743_RS14175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IM743_RS14185	COG0156	8-amino-7-oxononanoate synthase activity
IM743_RS14190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IM743_RS14200	COG1073	alpha beta
IM743_RS14205	COG1609	Transcriptional regulator
IM743_RS14210	COG1653	transport
IM743_RS14215	COG1175	transmembrane transport
IM743_RS14220	COG0395	ABC-type sugar transport system, permease component
IM743_RS14225	COG1486	melibiose metabolic process
IM743_RS14230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IM743_RS14235	COG0495	leucyl-tRNA aminoacylation
IM743_RS14245	COG2202	Pas domain
IM743_RS14245	COG1366	Belongs to the anti-sigma-factor antagonist family
IM743_RS14250	COG2814	Major facilitator Superfamily
IM743_RS14255	COG2433	Pfam Transposase IS66
IM743_RS14260	COG0577	efflux transmembrane transporter activity
IM743_RS14265	COG1136	(ABC) transporter
IM743_RS14270	COG2205	protein histidine kinase activity
IM743_RS14275	COG0745	RESPONSE REGULATOR receiver
IM743_RS14280	COG0577	efflux transmembrane transporter activity
IM743_RS14285	COG1136	(ABC) transporter
IM743_RS14300	COG1131	(ABC) transporter
IM743_RS14305	COG1725	Transcriptional regulator
IM743_RS14320	COG1242	4 iron, 4 sulfur cluster binding
IM743_RS14325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IM743_RS14335	COG2267	carboxylic ester hydrolase activity
IM743_RS14340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IM743_RS14345	COG1113	amino acid transport
IM743_RS14350	COG0367	asparagine synthase
IM743_RS14355	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IM743_RS14360	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IM743_RS14370	COG1506	peptidase
IM743_RS14375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IM743_RS14380	COG1116	anion transmembrane transporter activity
IM743_RS14385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IM743_RS14390	COG0494	nUDIX hydrolase
IM743_RS14395	COG4824	toxin secretion phage lysis holin
IM743_RS14400	COG0783	Belongs to the Dps family
IM743_RS14415	COG1854	S-ribosylhomocysteine lyase activity
IM743_RS14420	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IM743_RS14425	COG0288	reversible hydration of carbon dioxide
IM743_RS14430	COG0254	rRNA binding
IM743_RS14435	COG1271	oxidase subunit
IM743_RS14440	COG1294	oxidase, subunit
IM743_RS14450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM743_RS14455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IM743_RS14455	COG1321	iron dependent repressor
IM743_RS14460	COG1121	(ABC) transporter
IM743_RS14465	COG0803	Belongs to the bacterial solute-binding protein 9 family
IM743_RS14470	COG4948	Mandelate Racemase Muconate Lactonizing
IM743_RS14475	COG0318	PFAM AMP-dependent synthetase and ligase
IM743_RS14480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IM743_RS14485	COG0596	Alpha beta hydrolase
IM743_RS14490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IM743_RS14495	COG1169	isochorismate synthase
IM743_RS14500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IM743_RS14505	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IM743_RS14510	COG0058	SHG alpha-glucan phosphorylase activity
IM743_RS14515	COG0297	glycogen (starch) synthase activity
IM743_RS14520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM743_RS14525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IM743_RS14530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IM743_RS14640	COG3859	Proton-coupled thiamine transporter YuaJ
IM743_RS14645	COG1247	-acetyltransferase
IM743_RS14650	COG2268	Band 7 protein
IM743_RS14655	COG1585	Membrane protein implicated in regulation of membrane protease activity
IM743_RS14660	COG2318	DinB family
IM743_RS14670	COG1454	alcohol dehydrogenase
IM743_RS14675	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS14680	COG1510	regulation of RNA biosynthetic process
IM743_RS14690	COG0569	domain protein
IM743_RS14695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IM743_RS14700	COG4682	membrane
IM743_RS14705	COG1705	Flagellar rod assembly protein muramidase FlgJ
IM743_RS14710	COG0477	Major facilitator Superfamily
IM743_RS14715	COG5553	Cysteine dioxygenase type I
IM743_RS14725	COG1968	undecaprenyl-diphosphatase activity
IM743_RS14730	COG0628	permease
IM743_RS14735	COG0673	inositol 2-dehydrogenase activity
IM743_RS14740	COG4806	L-rhamnose isomerase
IM743_RS14745	COG3254	rhamnose metabolic process
IM743_RS14750	COG1070	Carbohydrate kinase
IM743_RS14755	COG1349	DNA-binding transcription factor activity
IM743_RS14760	COG3347	Dehydrogenase
IM743_RS14760	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS14765	COG0840	transmembrane signaling receptor activity
IM743_RS14770	COG0840	transmembrane signaling receptor activity
IM743_RS14775	COG0840	transmembrane signaling receptor activity
IM743_RS14780	COG0840	transmembrane signaling receptor activity
IM743_RS14795	COG2070	2-Nitropropane dioxygenase
IM743_RS14800	COG0432	Pfam Uncharacterised protein family UPF0047
IM743_RS14805	COG0366	Alpha amylase catalytic
IM743_RS14810	COG1253	flavin adenine dinucleotide binding
IM743_RS14815	COG2738	Putative neutral zinc metallopeptidase
IM743_RS14830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IM743_RS14845	COG0166	Belongs to the GPI family
IM743_RS14850	COG1979	alcohol dehydrogenase
IM743_RS14855	COG1979	alcohol dehydrogenase
IM743_RS14860	COG2155	Conserved Protein
IM743_RS14865	COG1098	S1 RNA binding domain
IM743_RS14870	COG0436	Aminotransferase
IM743_RS14875	COG1522	sequence-specific DNA binding
IM743_RS14880	COG2267	carboxylic ester hydrolase activity
IM743_RS14890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IM743_RS14895	COG2205	protein histidine kinase activity
IM743_RS14905	COG5018	Exonuclease
IM743_RS14910	COG2814	Major facilitator Superfamily
IM743_RS14915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM743_RS14920	COG3011	Protein conserved in bacteria
IM743_RS14930	COG3290	protein histidine kinase activity
IM743_RS14935	COG4565	transcriptional regulatory protein
IM743_RS14940	COG1744	ABC transporter substrate-binding protein PnrA-like
IM743_RS14945	COG3845	ABC transporter
IM743_RS14950	COG4603	Belongs to the binding-protein-dependent transport system permease family
IM743_RS14955	COG1079	Belongs to the binding-protein-dependent transport system permease family
IM743_RS14960	COG3493	citrate carrier protein
IM743_RS14970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IM743_RS14970	COG2111	Na H antiporter
IM743_RS14975	COG2111	Na H antiporter
IM743_RS14980	COG1006	Multisubunit Na H antiporter MnhC subunit
IM743_RS14985	COG0651	ATP synthesis coupled electron transport
IM743_RS14990	COG1863	multisubunit Na H antiporter MnhE subunit
IM743_RS14995	COG2212	antiporter activity
IM743_RS15000	COG1320	monovalent cation:proton antiporter activity
IM743_RS15005	COG2050	protein possibly involved in aromatic compounds catabolism
IM743_RS15010	COG2197	response regulator
IM743_RS15015	COG4585	Histidine kinase
IM743_RS15025	COG0142	geranyltranstransferase activity
IM743_RS15040	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IM743_RS15045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IM743_RS15050	COG1335	isochorismatase
IM743_RS15055	COG5506	Protein of unknown function (DUF1694)
IM743_RS15070	COG0628	permease
IM743_RS15080	COG1418	mRNA catabolic process
IM743_RS15085	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS15095	COG1511	domain protein
IM743_RS15100	COG1674	ftsk spoiiie
IM743_RS15100	COG0433	COG0433 Predicted ATPase
IM743_RS15105	COG4499	WXG100 protein secretion system (Wss), protein YukC
IM743_RS15110	COG5417	Belongs to the EsaB family
IM743_RS15115	COG4842	Belongs to the WXG100 family
IM743_RS15120	COG2508	Transcriptional regulator
IM743_RS15120	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IM743_RS15125	COG0686	Belongs to the AlaDH PNT family
IM743_RS15130	COG5634	Uncharacterized conserved protein (DUF2278)
IM743_RS15140	COG3251	PFAM MbtH domain protein
IM743_RS15145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS15150	COG3433	isochorismatase activity
IM743_RS15150	COG1535	isochorismatase
IM743_RS15155	COG1021	2,3-dihydroxybenzoate-AMP ligase
IM743_RS15160	COG1169	isochorismate synthase
IM743_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS15170	COG2819	hydrolase of the alpha beta superfamily
IM743_RS15175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IM743_RS15180	COG1268	BioY protein
IM743_RS15185	COG2056	Na+-H+ antiporter family
IM743_RS15190	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IM743_RS15195	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IM743_RS15200	COG3584	3D domain protein
IM743_RS15215	COG1252	NADH dehydrogenase
IM743_RS15220	COG0492	ferredoxin-NADP+ reductase activity
IM743_RS15250	COG0516	GMP reductase activity
IM743_RS15255	COG0316	Belongs to the HesB IscA family
IM743_RS15260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IM743_RS15265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM743_RS15275	COG4844	belongs to the
IM743_RS15280	COG1252	NADH dehydrogenase
IM743_RS15285	COG4837	Protein of unknown function (DUF1462)
IM743_RS15290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IM743_RS15295	COG0823	Involved in the tonB-independent uptake of proteins
IM743_RS15295	COG4946	Tricorn protease homolog
IM743_RS15295	COG1506	peptidase
IM743_RS15300	COG0083	homoserine kinase activity
IM743_RS15305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IM743_RS15310	COG0460	homoserine dehydrogenase
IM743_RS15315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IM743_RS15320	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IM743_RS15325	COG0647	UMP catabolic process
IM743_RS15330	COG2445	Protein of unknown function DUF86
IM743_RS15335	COG4470	Protein conserved in bacteria
IM743_RS15350	COG0739	heme binding
IM743_RS15360	COG3377	Domain of unknown function (DUF1805)
IM743_RS15365	COG0737	Belongs to the 5'-nucleotidase family
IM743_RS15370	COG0730	response to heat
IM743_RS15375	COG1801	Protein of unknown function DUF72
IM743_RS15385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IM743_RS15390	COG2508	Transcriptional regulator
IM743_RS15395	COG2233	PERMEase
IM743_RS15400	COG2233	PERMEase
IM743_RS15405	COG3195	allantoin biosynthetic process
IM743_RS15405	COG3648	Uricase
IM743_RS15410	COG2351	hydroxyisourate hydrolase activity
IM743_RS15425	COG2080	2 iron, 2 sulfur cluster binding
IM743_RS15430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IM743_RS15435	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
IM743_RS15440	COG2068	MobA-Related Protein
IM743_RS15445	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IM743_RS15450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IM743_RS15455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IM743_RS15460	COG2356	endonuclease I
IM743_RS15465	COG3842	ATPase activity
IM743_RS15470	COG2188	Transcriptional regulator
IM743_RS15475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM743_RS15480	COG0395	ABC-type sugar transport system, permease component
IM743_RS15485	COG1175	transmembrane transport
IM743_RS15490	COG1653	transport
IM743_RS15495	COG2222	sugar isomerase
IM743_RS15500	COG0322	excinuclease ABC activity
IM743_RS15505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IM743_RS15520	COG0719	Fe-S assembly protein
IM743_RS15525	COG0822	iron-sulfur transferase activity
IM743_RS15530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IM743_RS15535	COG0719	Fe-S assembly protein
IM743_RS15540	COG0396	ATPase activity
IM743_RS15550	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IM743_RS15555	COG1464	Belongs to the NlpA lipoprotein family
IM743_RS15560	COG2011	ABC-type metal ion transport system permease component
IM743_RS15565	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IM743_RS15575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IM743_RS15580	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IM743_RS15590	COG0509	glycine decarboxylation via glycine cleavage system
IM743_RS15595	COG1393	Belongs to the ArsC family
IM743_RS15600	COG1960	acyl-CoA dehydrogenase activity
IM743_RS15605	COG0183	Belongs to the thiolase family
IM743_RS15610	COG1024	Enoyl-CoA hydratase
IM743_RS15610	COG1250	3-hydroxyacyl-CoA dehydrogenase
IM743_RS15620	COG0506	proline dehydrogenase activity
IM743_RS15630	COG5577	PFAM Coat F domain
IM743_RS15635	COG1846	Transcriptional regulator
IM743_RS15640	COG0477	Major facilitator Superfamily
IM743_RS15645	COG1942	4-Oxalocrotonate Tautomerase
IM743_RS15650	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS15655	COG0583	DNA-binding transcription factor activity
IM743_RS15665	COG1120	ATPase activity
IM743_RS15680	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS15685	COG0783	Belongs to the Dps family
IM743_RS15690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM743_RS15695	COG0745	RESPONSE REGULATOR receiver
IM743_RS15700	COG2205	protein histidine kinase activity
IM743_RS15700	COG2770	Histidine kinase
IM743_RS15710	COG1309	transcriptional regulator
IM743_RS15715	COG0114	fumarate hydratase activity
IM743_RS15725	COG0697	spore germination
IM743_RS15730	COG0814	amino acid
IM743_RS15740	COG2197	response regulator
IM743_RS15745	COG4585	Histidine kinase
IM743_RS15750	COG4758	membrane
IM743_RS15755	COG3595	metallopeptidase activity
IM743_RS15760	COG1842	Phage shock protein A
IM743_RS15765	COG4758	membrane
IM743_RS15770	COG2814	Major facilitator Superfamily
IM743_RS15775	COG2096	Adenosyltransferase
IM743_RS15780	COG1120	ATPase activity
IM743_RS15785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS15790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS15800	COG3386	PFAM SMP-30 Gluconolaconase
IM743_RS15805	COG2205	protein histidine kinase activity
IM743_RS15810	COG0745	RESPONSE REGULATOR receiver
IM743_RS15820	COG1191	sigma factor activity
IM743_RS15830	COG2140	Oxalate decarboxylase
IM743_RS15840	COG0577	efflux transmembrane transporter activity
IM743_RS15845	COG1136	(ABC) transporter
IM743_RS15850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IM743_RS15855	COG1120	ATPase activity
IM743_RS15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IM743_RS15870	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS15875	COG0531	amino acid
IM743_RS15885	COG1988	membrane-bound metal-dependent
IM743_RS15890	COG1368	sulfuric ester hydrolase activity
IM743_RS15895	COG1910	domain protein
IM743_RS15900	COG0725	ABC transporter, periplasmic molybdate-binding protein
IM743_RS15905	COG4149	molybdate abc transporter
IM743_RS15910	COG0656	L-ascorbic acid biosynthetic process
IM743_RS15920	COG0025	NhaP-type Na H and K H
IM743_RS15925	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IM743_RS15930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IM743_RS15935	COG3973	AAA domain
IM743_RS15945	COG2860	membrane
IM743_RS15950	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IM743_RS15955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IM743_RS15960	COG2217	Heavy metal translocating P-type atpase
IM743_RS15965	COG2217	Heavy metal translocating P-type atpase
IM743_RS15970	COG2608	mercury ion transmembrane transporter activity
IM743_RS15975	COG1937	Protein conserved in bacteria
IM743_RS15980	COG0673	inositol 2-dehydrogenase activity
IM743_RS15985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IM743_RS15990	COG1289	transmembrane transporter activity
IM743_RS15995	COG1802	Transcriptional regulator
IM743_RS16000	COG0697	spore germination
IM743_RS16010	COG2076	Multidrug Resistance protein
IM743_RS16015	COG1309	transcriptional regulator
IM743_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS16030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IM743_RS16035	COG0557	exoribonuclease II activity
IM743_RS16040	COG1647	Serine aminopeptidase, S33
IM743_RS16045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IM743_RS16050	COG0596	Alpha beta hydrolase
IM743_RS16055	COG1476	TRANSCRIPTIONal
IM743_RS16060	COG1396	sequence-specific DNA binding
IM743_RS16065	COG1396	sequence-specific DNA binding
IM743_RS16070	COG1733	regulation of RNA biosynthetic process
IM743_RS16075	COG0840	transmembrane signaling receptor activity
IM743_RS16080	COG1174	glycine betaine transport
IM743_RS16085	COG1732	Glycine betaine
IM743_RS16090	COG1174	glycine betaine transport
IM743_RS16095	COG1125	glycine betaine transport
IM743_RS16095	COG0517	IMP dehydrogenase activity
IM743_RS16100	COG1510	regulation of RNA biosynthetic process
IM743_RS16105	COG1174	glycine betaine transport
IM743_RS16110	COG1732	Glycine betaine
IM743_RS16115	COG1174	glycine betaine transport
IM743_RS16120	COG0517	IMP dehydrogenase activity
IM743_RS16120	COG1125	glycine betaine transport
IM743_RS16125	COG1510	regulation of RNA biosynthetic process
IM743_RS16135	COG3064	Membrane
IM743_RS16140	COG4640	response to antibiotic
IM743_RS16145	COG0456	acetyltransferase
IM743_RS16160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
IM743_RS16180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS16185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM743_RS16195	COG2234	aminopeptidase activity
IM743_RS16205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IM743_RS16210	COG0149	triose-phosphate isomerase activity
IM743_RS16215	COG0126	phosphoglycerate kinase activity
IM743_RS16225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IM743_RS16230	COG2390	Transcriptional regulator
IM743_RS16235	COG2814	Major facilitator Superfamily
IM743_RS16240	COG1609	Transcriptional regulator
IM743_RS16245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM743_RS16250	COG0583	DNA-binding transcription factor activity
IM743_RS16255	COG0697	spore germination
IM743_RS16260	COG1113	amino acid transport
IM743_RS16265	COG3858	chitin binding
IM743_RS16270	COG1556	Lactate utilization protein
IM743_RS16275	COG1139	Iron-sulfur cluster binding protein
IM743_RS16280	COG0247	lactate metabolic process
IM743_RS16285	COG2197	response regulator
IM743_RS16290	COG4585	Histidine kinase
IM743_RS16295	COG0842	Transport permease protein
IM743_RS16300	COG1131	(ABC) transporter
IM743_RS16305	COG0596	Alpha beta hydrolase
IM743_RS16310	COG2208	phosphoserine phosphatase activity
IM743_RS16315	COG3867	Arabinogalactan endo-beta-1,4-galactanase
IM743_RS16320	COG1874	Beta-galactosidase
IM743_RS16325	COG3833	ABC-type maltose transport systems, permease component
IM743_RS16330	COG1175	transmembrane transport
IM743_RS16335	COG2182	Extracellular solute-binding protein
IM743_RS16340	COG1609	Transcriptional regulator
IM743_RS16345	COG2186	Transcriptional regulator
IM743_RS16350	COG1620	l-lactate permease
IM743_RS16360	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IM743_RS16370	COG5039	Polysaccharide pyruvyl transferase
IM743_RS16375	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM743_RS16380	COG0110	maltose O-acetyltransferase activity
IM743_RS16385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IM743_RS16390	COG2244	polysaccharide biosynthetic process
IM743_RS16395	COG1216	Glycosyl transferase, family 2
IM743_RS16400	COG5039	Polysaccharide pyruvyl transferase
IM743_RS16405	COG1216	Glycosyl transferase, family 2
IM743_RS16415	COG0438	transferase activity, transferring glycosyl groups
IM743_RS16420	COG1215	transferase activity, transferring glycosyl groups
IM743_RS16425	COG0438	transferase activity, transferring glycosyl groups
IM743_RS16430	COG1086	Polysaccharide biosynthesis protein
IM743_RS16435	COG0489	protein tyrosine kinase activity
IM743_RS16440	COG3944	biosynthesis protein
IM743_RS16445	COG1396	sequence-specific DNA binding
IM743_RS16450	COG2272	Belongs to the type-B carboxylesterase lipase family
IM743_RS16460	COG3479	Phenolic acid decarboxylase
IM743_RS16470	COG1794	racemase activity, acting on amino acids and derivatives
IM743_RS16475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IM743_RS16485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM743_RS16490	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IM743_RS16495	COG0640	Transcriptional regulator
IM743_RS16500	COG1621	beta-fructofuranosidase activity
IM743_RS16505	COG1621	beta-fructofuranosidase activity
IM743_RS16510	COG0531	amino acid
IM743_RS16515	COG1309	transcriptional regulator
IM743_RS16520	COG2076	Multidrug Resistance protein
IM743_RS16525	COG2076	Multidrug Resistance protein
IM743_RS16545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IM743_RS16550	COG0366	Alpha amylase catalytic
IM743_RS16555	COG1554	hydrolase, family 65, central catalytic
IM743_RS16560	COG5521	maltodextrose utilization protein MalA
IM743_RS16565	COG3833	ABC-type maltose transport systems, permease component
IM743_RS16570	COG1175	transmembrane transport
IM743_RS16575	COG2182	Extracellular solute-binding protein
IM743_RS16580	COG0366	Alpha amylase catalytic
IM743_RS16585	COG1609	Transcriptional regulator
IM743_RS16590	COG1611	Belongs to the LOG family
IM743_RS16595	COG1694	Mazg nucleotide pyrophosphohydrolase
IM743_RS16600	COG0659	secondary active sulfate transmembrane transporter activity
IM743_RS16605	COG0288	reversible hydration of carbon dioxide
IM743_RS16610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IM743_RS16615	COG0577	efflux transmembrane transporter activity
IM743_RS16620	COG1136	(ABC) transporter
IM743_RS16625	COG5002	protein histidine kinase activity
IM743_RS16630	COG0745	RESPONSE REGULATOR receiver
IM743_RS16640	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IM743_RS16645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS16650	COG1481	regulation of sporulation
IM743_RS16655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IM743_RS16660	COG1660	Displays ATPase and GTPase activities
IM743_RS16665	COG1051	belongs to the nudix hydrolase family
IM743_RS16670	COG0492	ferredoxin-NADP+ reductase activity
IM743_RS16675	COG3883	PFAM NLP P60 protein
IM743_RS16675	COG0791	NLP P60 protein
IM743_RS16680	COG0457	Tetratricopeptide repeat
IM743_RS16685	COG1132	(ABC) transporter
IM743_RS16705	COG0140	phosphoribosyl-ATP diphosphatase activity
IM743_RS16705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IM743_RS16710	COG0107	imidazoleglycerol-phosphate synthase activity
IM743_RS16715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IM743_RS16720	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IM743_RS16725	COG0131	Imidazoleglycerol-phosphate dehydratase
IM743_RS16730	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IM743_RS16735	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IM743_RS16740	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IM743_RS16745	COG4990	cell redox homeostasis
IM743_RS16750	COG5297	Belongs to the glycosyl hydrolase family 6
IM743_RS16755	COG0110	maltose O-acetyltransferase activity
IM743_RS16760	COG0546	phosphoglycolate phosphatase activity
IM743_RS16765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
IM743_RS16770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IM743_RS16775	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IM743_RS16780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IM743_RS16785	COG0363	glucosamine-6-phosphate deaminase activity
IM743_RS16790	COG2188	Transcriptional regulator
IM743_RS16795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IM743_RS16800	COG1950	PFAM Membrane protein of
IM743_RS16805	COG1983	PspC domain protein
IM743_RS16810	COG3595	metallopeptidase activity
IM743_RS16825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IM743_RS16835	COG4897	Protein conserved in bacteria
IM743_RS16840	COG3848	Pyruvate phosphate dikinase
IM743_RS16840	COG0574	Belongs to the PEP-utilizing enzyme family
IM743_RS16845	COG1309	transcriptional regulator
IM743_RS16850	COG2814	Major facilitator Superfamily
IM743_RS16855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM743_RS16865	COG3409	Peptidoglycan-binding domain 1 protein
IM743_RS16865	COG0793	Belongs to the peptidase S41A family
IM743_RS16870	COG2177	Part of the ABC transporter FtsEX involved in
IM743_RS16875	COG2884	Cell division ATP-binding protein ftsE
IM743_RS16880	COG2010	Cytochrome c
IM743_RS16885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS16895	COG0653	protein targeting
IM743_RS16900	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IM743_RS16915	COG1516	flagellar protein fliS
IM743_RS16920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IM743_RS16925	COG1334	flagellar protein FlaG
IM743_RS16930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM743_RS16935	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IM743_RS16940	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IM743_RS16950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IM743_RS16955	COG1256	bacterial-type flagellum assembly
IM743_RS16955	COG4786	Flagellar basal body rod
IM743_RS16960	COG3418	PFAM FlgN family protein
IM743_RS16965	COG2747	anti-sigma28 factor FlgM
IM743_RS16975	COG1040	competence protein
IM743_RS16985	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IM743_RS16990	COG1307	EDD domain protein, DegV family
IM743_RS16995	COG2197	response regulator
IM743_RS17000	COG4585	Histidine kinase
IM743_RS17005	COG1739	Uncharacterized protein family UPF0029
IM743_RS17010	COG1316	TRANSCRIPTIONal
IM743_RS17015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IM743_RS17020	COG0438	transferase activity, transferring glycosyl groups
IM743_RS17025	COG1215	transferase activity, transferring glycosyl groups
IM743_RS17030	COG3206	protein involved in exopolysaccharide biosynthesis
IM743_RS17035	COG3307	-O-antigen
IM743_RS17040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM743_RS17045	COG0297	glycogen (starch) synthase activity
IM743_RS17045	COG0438	transferase activity, transferring glycosyl groups
IM743_RS17050	COG2244	polysaccharide biosynthetic process
IM743_RS17060	COG0860	N-Acetylmuramoyl-L-alanine amidase
IM743_RS17060	COG2247	cell wall binding repeat
IM743_RS17065	COG2247	cell wall binding repeat
IM743_RS17065	COG2385	sporulation resulting in formation of a cellular spore
IM743_RS17075	COG1316	TRANSCRIPTIONal
IM743_RS17080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IM743_RS17085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IM743_RS17090	COG1682	transport, permease protein
IM743_RS17100	COG0438	transferase activity, transferring glycosyl groups
IM743_RS17105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM743_RS17135	COG1134	teichoic acid transport
IM743_RS17140	COG1682	transport, permease protein
IM743_RS17145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM743_RS17150	COG0438	transferase activity, transferring glycosyl groups
IM743_RS17155	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IM743_RS17160	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
IM743_RS17165	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM743_RS17175	COG4193	domain, Protein
IM743_RS17180	COG1482	cell wall glycoprotein biosynthetic process
IM743_RS17185	COG0697	spore germination
IM743_RS17190	COG0814	amino acid
IM743_RS17200	COG2814	Major facilitator Superfamily
IM743_RS17205	COG1316	TRANSCRIPTIONal
IM743_RS17210	COG0561	phosphatase activity
IM743_RS17215	COG0791	NLP P60 protein
IM743_RS17225	COG2843	Capsule synthesis protein
IM743_RS17235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IM743_RS17240	COG1609	Transcriptional regulator
IM743_RS17245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM743_RS17250	COG1869	D-ribose catabolic process
IM743_RS17255	COG1129	ABC transporter
IM743_RS17260	COG1172	Belongs to the binding-protein-dependent transport system permease family
IM743_RS17265	COG1879	ABC-type sugar transport system periplasmic component
IM743_RS17270	COG3103	Sh3 type 3 domain protein
IM743_RS17280	COG2249	NAD(P)H dehydrogenase (quinone) activity
IM743_RS17285	COG3527	Alpha-acetolactate decarboxylase
IM743_RS17290	COG0028	Belongs to the TPP enzyme family
IM743_RS17295	COG0583	DNA-binding transcription factor activity
IM743_RS17300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IM743_RS17315	COG5337	Spore coat protein CotH
IM743_RS17325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM743_RS17330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS17345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IM743_RS17355	COG0405	Gamma-glutamyltransferase
IM743_RS17360	COG1522	sequence-specific DNA binding
IM743_RS17365	COG2059	Chromate
IM743_RS17370	COG2059	Chromate
IM743_RS17380	COG0655	NAD(P)H dehydrogenase (quinone) activity
IM743_RS17385	COG0583	DNA-binding transcription factor activity
IM743_RS17420	COG5444	nuclease activity
IM743_RS17445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IM743_RS17450	COG4464	protein tyrosine phosphatase activity
IM743_RS17455	COG0489	protein tyrosine kinase activity
IM743_RS17460	COG3944	biosynthesis protein
IM743_RS17470	COG4715	Zinc finger, swim domain protein
IM743_RS17475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IM743_RS17480	COG0561	phosphatase activity
IM743_RS17485	COG1349	DNA-binding transcription factor activity
IM743_RS17490	COG0629	single-stranded DNA binding
IM743_RS17505	COG2602	Beta-lactamase
IM743_RS17510	COG1970	mechanosensitive ion channel activity
IM743_RS17515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IM743_RS17520	COG0457	Tetratricopeptide repeat
IM743_RS17525	COG4786	Flagellar basal body rod
IM743_RS17530	COG4786	Flagellar basal body rod
IM743_RS17535	COG1077	Cell shape determining protein MreB Mrl
IM743_RS17540	COG1609	Transcriptional regulator
IM743_RS17550	COG1846	Transcriptional regulator
IM743_RS17555	COG2814	Major facilitator Superfamily
IM743_RS17560	COG3420	alginic acid biosynthetic process
IM743_RS17565	COG1953	Uracil, thiamine, allantoin
IM743_RS17570	COG0477	Major facilitator Superfamily
IM743_RS17585	COG0004	ammonium transporteR
IM743_RS17590	COG0347	Belongs to the P(II) protein family
IM743_RS17595	COG0671	phosphoesterase, PA-phosphatase related
IM743_RS17605	COG0739	heme binding
IM743_RS17610	COG1247	-acetyltransferase
IM743_RS17620	COG1086	Polysaccharide biosynthesis protein
IM743_RS17625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IM743_RS17630	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM743_RS17635	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IM743_RS17650	COG2089	acid synthase
IM743_RS17660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM743_RS17670	COG2910	NAD(P)H-binding
IM743_RS17675	COG1959	2 iron, 2 sulfur cluster binding
IM743_RS17680	COG0804	urea catabolic process
IM743_RS17685	COG0832	Belongs to the urease beta subunit family
IM743_RS17690	COG0831	urea catabolic process
IM743_RS17720	COG3237	CsbD-like
IM743_RS17725	COG1994	Peptidase M50
IM743_RS17730	COG0457	Tetratricopeptide repeat
IM743_RS17735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IM743_RS17740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IM743_RS17750	COG2304	oxidoreductase activity
IM743_RS17755	COG2304	oxidoreductase activity
IM743_RS17760	COG2385	sporulation resulting in formation of a cellular spore
IM743_RS17765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM743_RS17775	COG4836	Membrane
IM743_RS17785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IM743_RS17790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IM743_RS17795	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IM743_RS17805	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IM743_RS17810	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IM743_RS17820	COG0356	it plays a direct role in the translocation of protons across the membrane
IM743_RS17830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IM743_RS17835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IM743_RS17840	COG4475	Protein of unknown function (DUF436)
IM743_RS17845	COG0698	ribose 5-phosphate isomerase
IM743_RS17850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IM743_RS17855	COG1971	Probably functions as a manganese efflux pump
IM743_RS17860	COG0009	L-threonylcarbamoyladenylate synthase
IM743_RS17865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IM743_RS17885	COG2890	protein-(glutamine-N5) methyltransferase activity
IM743_RS17890	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IM743_RS17895	COG0346	lactoylglutathione lyase activity
IM743_RS17900	COG0789	Transcriptional regulator
IM743_RS17905	COG0679	Auxin Efflux Carrier
IM743_RS17910	COG0281	malic enzyme
IM743_RS17915	COG1435	thymidine kinase activity
IM743_RS17925	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IM743_RS17935	COG1494	fructose-1,6-bisphosphatase
IM743_RS17940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IM743_RS17945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IM743_RS17950	COG0191	fructose-bisphosphate aldolase activity
IM743_RS17955	COG2204	response regulator
IM743_RS17960	COG4821	SIS domain
IM743_RS17965	COG0504	CTP synthase activity
IM743_RS17970	COG3343	RNA polymerase activity
IM743_RS17975	COG1960	acyl-CoA dehydrogenase activity
IM743_RS17980	COG2181	nitrate reductase activity
IM743_RS17980	COG0247	lactate metabolic process
IM743_RS17985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM743_RS17990	COG4294	response to UV
IM743_RS18000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IM743_RS18005	COG1132	(ABC) transporter
IM743_RS18010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IM743_RS18020	COG2181	nitrate reductase activity
IM743_RS18025	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IM743_RS18030	COG1140	nitrate reductase beta subunit
IM743_RS18035	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IM743_RS18040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM743_RS18050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IM743_RS18055	COG2223	nitrite transmembrane transporter activity
IM743_RS18060	COG0018	arginyl-trna synthetase
IM743_RS18065	COG4506	Protein conserved in bacteria
IM743_RS18075	COG0535	radical SAM domain protein
IM743_RS18085	COG1131	(ABC) transporter
IM743_RS18095	COG0612	Peptidase, M16
IM743_RS18120	COG3391	amine dehydrogenase activity
IM743_RS18125	COG0457	Tetratricopeptide repeat
IM743_RS18135	COG0010	Belongs to the arginase family
IM743_RS18140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IM743_RS18145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IM743_RS18160	COG1994	Peptidase M50
IM743_RS18165	COG1942	4-Oxalocrotonate Tautomerase
IM743_RS18170	COG1846	Transcriptional regulator
IM743_RS18175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IM743_RS18180	COG0477	Major facilitator Superfamily
IM743_RS18185	COG1959	2 iron, 2 sulfur cluster binding
IM743_RS18190	COG3465	dGTPase activity
IM743_RS18195	COG1078	dGTPase activity
IM743_RS18200	COG4844	belongs to the
IM743_RS18210	COG0697	spore germination
IM743_RS18215	COG0095	Lipoate-protein ligase
IM743_RS18220	COG0583	DNA-binding transcription factor activity
IM743_RS18225	COG0280	phosphate acetyltransferase
IM743_RS18230	COG3253	May function as heme-dependent peroxidase
IM743_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS18240	COG0436	Aminotransferase
IM743_RS18245	COG2814	Major facilitator Superfamily
IM743_RS18250	COG0151	Belongs to the GarS family
IM743_RS18255	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS18260	COG1917	Cupin 2, conserved barrel domain protein
IM743_RS18265	COG0077	Prephenate dehydratase
IM743_RS18270	COG2814	Major facilitator Superfamily
IM743_RS18280	COG0833	amino acid
IM743_RS18285	COG4187	Peptidase family M20/M25/M40
IM743_RS18290	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS18295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IM743_RS18305	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IM743_RS18310	COG1091	dTDP-4-dehydrorhamnose reductase activity
IM743_RS18315	COG1088	dTDP-glucose 4,6-dehydratase activity
IM743_RS18320	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IM743_RS18325	COG3980	spore coat polysaccharide biosynthesis protein
IM743_RS18330	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
IM743_RS18335	COG2089	acid synthase
IM743_RS18340	COG0456	acetyltransferase
IM743_RS18345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IM743_RS18350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IM743_RS18355	COG0463	Glycosyl transferase, family 2
IM743_RS18365	COG2363	Small membrane protein
IM743_RS18370	COG2233	PERMEase
IM743_RS18380	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS18385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IM743_RS18390	COG1216	Glycosyl transferase, family 2
IM743_RS18405	COG1695	Transcriptional regulator
IM743_RS18410	COG0351	phosphomethylpyrimidine kinase
IM743_RS18425	COG1621	beta-fructofuranosidase activity
IM743_RS18430	COG1263	PTS System
IM743_RS18430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS18435	COG2116	formate transmembrane transporter activity
IM743_RS18440	COG3711	transcriptional antiterminator
IM743_RS18450	COG1404	Belongs to the peptidase S8 family
IM743_RS18455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM743_RS18460	COG0778	Nitroreductase
IM743_RS18465	COG0772	Belongs to the SEDS family
IM743_RS18490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IM743_RS18495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IM743_RS18500	COG2261	transglycosylase associated protein
IM743_RS18505	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IM743_RS18510	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IM743_RS18515	COG2246	polysaccharide biosynthetic process
IM743_RS18520	COG1309	transcriptional regulator
IM743_RS18530	COG3162	membrane
IM743_RS18535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IM743_RS18540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IM743_RS18545	COG2837	iron assimilation
IM743_RS18550	COG2822	iron ion transport
IM743_RS18555	COG0672	)-iron permease
IM743_RS18560	COG0352	thiamine-phosphate diphosphorylase activity
IM743_RS18565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IM743_RS18570	COG0583	DNA-binding transcription factor activity
IM743_RS18575	COG1380	Effector of murein hydrolase LrgA
IM743_RS18580	COG1346	cytolysis
IM743_RS18585	COG2814	Major facilitator Superfamily
IM743_RS18590	COG4895	conserved protein (DUF2196)
IM743_RS18595	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IM743_RS18600	COG0346	lactoylglutathione lyase activity
IM743_RS18610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM743_RS18615	COG1404	Belongs to the peptidase S8 family
IM743_RS18620	COG1263	PTS System
IM743_RS18620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS18625	COG3711	transcriptional antiterminator
IM743_RS18630	COG1442	glycosyl transferase family 8
IM743_RS18635	COG5522	Integral membrane protein (intg_mem_TP0381)
IM743_RS18640	COG1846	Transcriptional regulator
IM743_RS18645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IM743_RS18650	COG2234	aminopeptidase activity
IM743_RS18655	COG2357	RelA SpoT domain protein
IM743_RS18660	COG1575	Belongs to the MenA family. Type 1 subfamily
IM743_RS18670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IM743_RS18675	COG1696	Membrane protein involved in D-alanine export
IM743_RS18680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IM743_RS18685	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IM743_RS18690	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IM743_RS18695	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IM743_RS18700	COG1486	melibiose metabolic process
IM743_RS18705	COG1447	Phosphotransferase system cellobiose-specific component IIA
IM743_RS18710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM743_RS18715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IM743_RS18720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IM743_RS18720	COG3711	transcriptional antiterminator
IM743_RS18730	COG2094	Belongs to the DNA glycosylase MPG family
IM743_RS18735	COG0753	catalase activity
IM743_RS18740	COG2814	Major facilitator Superfamily
IM743_RS18745	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IM743_RS18750	COG1131	(ABC) transporter
IM743_RS18770	COG1595	DNA-templated transcription, initiation
IM743_RS18775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IM743_RS18780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IM743_RS18785	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IM743_RS18790	COG4988	ABC transporter
IM743_RS18795	COG1294	oxidase, subunit
IM743_RS18800	COG1271	oxidase subunit
IM743_RS18805	COG3493	citrate carrier protein
IM743_RS18810	COG0501	Belongs to the peptidase M48B family
IM743_RS18820	COG0726	polysaccharide deacetylase
IM743_RS18830	COG3842	ATPase activity
IM743_RS18835	COG2508	Transcriptional regulator
IM743_RS18840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IM743_RS18850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IM743_RS18860	COG2195	Cleaves the N-terminal amino acid of tripeptides
IM743_RS18870	COG4894	glucomannan catabolic process
IM743_RS18875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM743_RS18880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IM743_RS18885	COG3290	protein histidine kinase activity
IM743_RS18885	COG3829	transcription factor binding
IM743_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS18895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IM743_RS18900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IM743_RS18905	COG2610	gluconate transmembrane transporter activity
IM743_RS18910	COG0500	methyltransferase
IM743_RS18915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM743_RS18930	COG0693	protein deglycase activity
IM743_RS18930	COG0753	catalase activity
IM743_RS18935	COG2851	Citrate transporter
IM743_RS18945	COG2723	6-phospho-beta-galactosidase activity
IM743_RS18950	COG2190	(PTS) system
IM743_RS18950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS18950	COG1263	PTS System
IM743_RS18955	COG3711	transcriptional antiterminator
IM743_RS18965	COG2270	Major facilitator Superfamily
IM743_RS18970	COG0513	Belongs to the DEAD box helicase family
IM743_RS18975	COG2755	lipolytic protein G-D-S-L family
IM743_RS18975	COG3401	FG-GAP repeat protein
IM743_RS19005	COG0697	spore germination
IM743_RS19010	COG0589	response to stress
IM743_RS19015	COG2723	6-phospho-beta-galactosidase activity
IM743_RS19020	COG2190	(PTS) system
IM743_RS19020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IM743_RS19020	COG1263	PTS System
IM743_RS19075	COG3507	Belongs to the glycosyl hydrolase 43 family
IM743_RS19090	COG2986	histidine ammonia-lyase
IM743_RS19095	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IM743_RS19100	COG1228	amidohydrolase
IM743_RS19105	COG0010	Belongs to the arginase family
IM743_RS19110	COG0833	amino acid
IM743_RS19115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IM743_RS19120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IM743_RS19125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IM743_RS19130	COG2390	Transcriptional regulator
IM743_RS19150	COG2079	MmgE PrpD family protein
IM743_RS19155	COG1473	amidohydrolase
IM743_RS19160	COG1126	abc transporter atp-binding protein
IM743_RS19165	COG0765	amino acid transport
IM743_RS19170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IM743_RS19175	COG0456	acetyltransferase
IM743_RS19180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IM743_RS19190	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
IM743_RS19195	COG0561	phosphatase activity
IM743_RS19225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IM743_RS19230	COG5294	Protein conserved in bacteria
IM743_RS19235	COG0577	efflux transmembrane transporter activity
IM743_RS19240	COG1136	(ABC) transporter
IM743_RS19245	COG2205	protein histidine kinase activity
IM743_RS19250	COG0745	RESPONSE REGULATOR receiver
IM743_RS19255	COG0191	fructose-bisphosphate aldolase activity
IM743_RS19265	COG1082	Xylose isomerase domain protein TIM barrel
IM743_RS19270	COG0673	inositol 2-dehydrogenase activity
IM743_RS19275	COG2814	Major facilitator Superfamily
IM743_RS19280	COG1082	Xylose isomerase domain protein TIM barrel
IM743_RS19285	COG3962	Belongs to the TPP enzyme family
IM743_RS19290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IM743_RS19300	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS19305	COG1349	DNA-binding transcription factor activity
IM743_RS19310	COG0667	Aldo Keto reductase
IM743_RS19335	COG2814	Major facilitator Superfamily
IM743_RS19340	COG0326	Molecular chaperone. Has ATPase activity
IM743_RS19350	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS19355	COG1309	transcriptional regulator
IM743_RS19360	COG1012	belongs to the aldehyde dehydrogenase family
IM743_RS19365	COG1714	RDD family
IM743_RS19370	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IM743_RS19380	COG1714	RDD family
IM743_RS19385	COG2311	Membrane
IM743_RS19390	COG1917	Cupin 2, conserved barrel domain protein
IM743_RS19395	COG1309	transcriptional regulator
IM743_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
IM743_RS19430	COG5039	Polysaccharide pyruvyl transferase
IM743_RS19435	COG1929	Belongs to the glycerate kinase type-1 family
IM743_RS19440	COG1802	Transcriptional regulator
IM743_RS19445	COG1070	Carbohydrate kinase
IM743_RS19450	COG2610	gluconate transmembrane transporter activity
IM743_RS19455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IM743_RS19460	COG0450	alkyl hydroperoxide reductase
IM743_RS19465	COG3634	alkyl hydroperoxide reductase activity
IM743_RS19485	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IM743_RS19515	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IM743_RS19530	COG1063	alcohol dehydrogenase
IM743_RS19550	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IM743_RS19560	COG0457	Tetratricopeptide repeat
IM743_RS19570	COG0010	Belongs to the arginase family
IM743_RS19575	COG0833	amino acid
IM743_RS19580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IM743_RS19600	COG5658	integral membrane protein
IM743_RS19605	COG0640	Transcriptional regulator
IM743_RS19610	COG3829	transcription factor binding
IM743_RS19615	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IM743_RS19620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IM743_RS19625	COG4853	Protein conserved in bacteria
IM743_RS19630	COG4863	YycH protein
IM743_RS19635	COG5002	protein histidine kinase activity
IM743_RS19640	COG0745	RESPONSE REGULATOR receiver
IM743_RS19670	COG0346	lactoylglutathione lyase activity
IM743_RS19675	COG0305	Participates in initiation and elongation during chromosome replication
IM743_RS19690	COG3093	addiction module antidote protein HigA
IM743_RS19695	COG2807	transmembrane transport
IM743_RS19700	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IM743_RS19705	COG0359	binds to the 23S rRNA
IM743_RS19710	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
IM743_RS19715	COG4241	membrane
IM743_RS19725	COG5577	PFAM Coat F domain
IM743_RS19730	COG1733	regulation of RNA biosynthetic process
IM743_RS19735	COG1227	inorganic diphosphatase activity
IM743_RS19745	COG2271	Major facilitator Superfamily
IM743_RS19750	COG0789	Transcriptional regulator
IM743_RS19750	COG4978	Transcriptional regulator
IM743_RS19765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IM743_RS19775	COG0640	Transcriptional regulator
IM743_RS19780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IM743_RS19785	COG2409	Drug exporters of the RND superfamily
IM743_RS19790	COG2197	response regulator
IM743_RS19795	COG4585	Histidine kinase
IM743_RS19805	COG1331	Highly conserved protein containing a thioredoxin domain
IM743_RS19810	COG4978	Transcriptional regulator
IM743_RS19810	COG0789	Transcriptional regulator
IM743_RS19815	COG1811	Na channel or pump
IM743_RS19830	COG0789	Transcriptional regulator
IM743_RS19835	COG0697	spore germination
IM743_RS19840	COG1331	Highly conserved protein containing a thioredoxin domain
IM743_RS19865	COG1331	Highly conserved protein containing a thioredoxin domain
IM743_RS19870	COG1266	CAAX protease self-immunity
IM743_RS19875	COG2814	Major facilitator Superfamily
IM743_RS19875	COG0477	Major facilitator Superfamily
IM743_RS19880	COG0110	maltose O-acetyltransferase activity
IM743_RS19885	COG0346	lactoylglutathione lyase activity
IM743_RS19890	COG1609	Transcriptional regulator
IM743_RS19895	COG0708	Exodeoxyribonuclease III
IM743_RS19905	COG0629	single-stranded DNA binding
IM743_RS19910	COG0360	Binds together with S18 to 16S ribosomal RNA
IM743_RS19915	COG0012	GTP binding
IM743_RS19920	COG0243	molybdopterin cofactor binding
IM743_RS19925	COG4481	Protein conserved in bacteria
IM743_RS19930	COG3949	Membrane
IM743_RS19940	COG1475	DNA binding
IM743_RS19945	COG1192	Involved in chromosome partitioning
IM743_RS19955	COG1475	DNA binding
IM743_RS19960	COG0357	Ribosomal RNA small subunit methyltransferase G
IM743_RS19965	COG0445	tRNA wobble uridine modification
IM743_RS19970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IM743_RS19975	COG1847	R3H domain protein
IM743_RS19980	COG0706	membrane insertase activity
IM743_RS19985	COG0594	ribonuclease P activity