locus-tag	class	description
ABE28_RS00020	COG0516	GMP reductase activity
ABE28_RS00020	COG0517	IMP dehydrogenase activity
ABE28_RS00040	COG1428	Deoxynucleoside kinase
ABE28_RS00045	COG1428	Deoxynucleoside kinase
ABE28_RS00050	COG1335	isochorismatase
ABE28_RS00055	COG0590	tRNA wobble adenosine to inosine editing
ABE28_RS00065	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABE28_RS00070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ABE28_RS00075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABE28_RS00110	COG1982	Orn Lys Arg decarboxylase major
ABE28_RS00115	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABE28_RS00120	COG3870	Protein conserved in bacteria
ABE28_RS00125	COG1728	Protein conserved in bacteria
ABE28_RS00130	COG0470	DNA polymerase III
ABE28_RS00135	COG1774	PSP1 C-terminal conserved region
ABE28_RS00140	COG4467	Involved in initiation control of chromosome replication
ABE28_RS00145	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ABE28_RS00155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ABE28_RS00160	COG2002	toxin-antitoxin pair type II binding
ABE28_RS00170	COG0084	hydrolase, TatD family'
ABE28_RS00175	COG3584	3D domain protein
ABE28_RS00175	COG3583	domain protein
ABE28_RS00195	COG4466	Protein conserved in bacteria
ABE28_RS00210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABE28_RS00215	COG0251	oxidation-reduction process
ABE28_RS00220	COG2088	sporulation resulting in formation of a cellular spore
ABE28_RS00225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABE28_RS00240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABE28_RS00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS00250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABE28_RS00255	COG1116	anion transmembrane transporter activity
ABE28_RS00260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ABE28_RS00275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABE28_RS00280	COG2002	toxin-antitoxin pair type II binding
ABE28_RS00285	COG2244	polysaccharide biosynthetic process
ABE28_RS00290	COG3956	TIGRFAM MazG family protein
ABE28_RS00295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABE28_RS00310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABE28_RS00315	COG1098	S1 RNA binding domain
ABE28_RS00330	COG2208	phosphoserine phosphatase activity
ABE28_RS00335	COG2304	oxidoreductase activity
ABE28_RS00340	COG0515	serine threonine protein kinase
ABE28_RS00350	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ABE28_RS00355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABE28_RS00360	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ABE28_RS00365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ABE28_RS00370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABE28_RS00375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABE28_RS00380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABE28_RS00385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ABE28_RS00390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABE28_RS00395	COG1396	sequence-specific DNA binding
ABE28_RS00400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABE28_RS00405	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ABE28_RS00430	COG3880	PFAM UvrB UvrC protein
ABE28_RS00435	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ABE28_RS00440	COG0542	response to heat
ABE28_RS00445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABE28_RS00455	COG4956	integral membrane protein (PIN domain superfamily)
ABE28_RS00460	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ABE28_RS00465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ABE28_RS00470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABE28_RS00475	COG1045	serine acetyltransferase
ABE28_RS00480	COG0215	cysteine-tRNA ligase activity
ABE28_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABE28_RS00495	COG3688	RNA-binding protein containing a PIN domain
ABE28_RS00510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABE28_RS00515	COG0250	Participates in transcription elongation, termination and antitermination
ABE28_RS00520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABE28_RS00525	COG0081	regulation of translation
ABE28_RS00540	COG2813	Specifically methylates the guanine in position
ABE28_RS00545	COG0085	RNA polymerase activity
ABE28_RS00550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABE28_RS00555	COG1358	cellular component organization or biogenesis
ABE28_RS00560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ABE28_RS00565	COG0049	tRNA binding
ABE28_RS00575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ABE28_RS00580	COG0051	transcription antitermination factor activity, RNA binding
ABE28_RS00585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABE28_RS00590	COG0088	Forms part of the polypeptide exit tunnel
ABE28_RS00600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABE28_RS00605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABE28_RS00610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ABE28_RS00615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABE28_RS00620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ABE28_RS00625	COG0255	Belongs to the universal ribosomal protein uL29 family
ABE28_RS00630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABE28_RS00635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABE28_RS00640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABE28_RS00650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABE28_RS00655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABE28_RS00660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ABE28_RS00665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ABE28_RS00670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ABE28_RS00675	COG1841	ribosomal large subunit assembly
ABE28_RS00680	COG0200	Binds to the 23S rRNA
ABE28_RS00685	COG0201	protein transport
ABE28_RS00690	COG0563	adenylate kinase activity
ABE28_RS00695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ABE28_RS00700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ABE28_RS00705	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABE28_RS00710	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ABE28_RS00715	COG0202	RNA polymerase activity
ABE28_RS00720	COG0203	ribosomal protein L17
ABE28_RS00725	COG1122	ATPase activity
ABE28_RS00730	COG1122	ATPase activity
ABE28_RS00735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABE28_RS00740	COG0101	tRNA pseudouridine synthase activity
ABE28_RS00745	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ABE28_RS00755	COG2814	Major facilitator Superfamily
ABE28_RS00775	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABE28_RS00780	COG0489	protein tyrosine kinase activity
ABE28_RS00790	COG2194	sulfuric ester hydrolase activity
ABE28_RS00795	COG0726	polysaccharide deacetylase
ABE28_RS00875	COG1595	DNA-templated transcription, initiation
ABE28_RS00880	COG5662	AntiSigma factor
ABE28_RS00885	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ABE28_RS00890	COG4856	YbbR-like protein
ABE28_RS00895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABE28_RS00900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABE28_RS00930	COG3850	Histidine kinase
ABE28_RS00930	COG5002	protein histidine kinase activity
ABE28_RS00940	COG1132	(ABC) transporter
ABE28_RS00945	COG0372	Belongs to the citrate synthase family
ABE28_RS00950	COG2079	MmgE PrpD family protein
ABE28_RS00955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ABE28_RS00965	COG0840	transmembrane signaling receptor activity
ABE28_RS00970	COG1278	Cold shock
ABE28_RS00985	COG1595	DNA-templated transcription, initiation
ABE28_RS00995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABE28_RS01005	COG2801	Transposase and inactivated derivatives
ABE28_RS01010	COG0493	'glutamate synthase
ABE28_RS01015	COG0167	dihydroorotate dehydrogenase activity
ABE28_RS01035	COG3835	regulator
ABE28_RS01040	COG1597	lipid kinase activity
ABE28_RS01045	COG0025	NhaP-type Na H and K H
ABE28_RS01050	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ABE28_RS01060	COG3842	ATPase activity
ABE28_RS01065	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABE28_RS01075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ABE28_RS01080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABE28_RS01095	COG2409	Drug exporters of the RND superfamily
ABE28_RS01095	COG1033	growth of symbiont in host cell
ABE28_RS01100	COG4821	SIS domain
ABE28_RS01105	COG2188	Transcriptional regulator
ABE28_RS01110	COG0363	glucosamine-6-phosphate deaminase activity
ABE28_RS01115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ABE28_RS01120	COG2190	(PTS) system
ABE28_RS01120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS01120	COG1263	PTS System
ABE28_RS01125	COG1120	ATPase activity
ABE28_RS01130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS01135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS01140	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS01145	COG2819	hydrolase of the alpha beta superfamily
ABE28_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS01155	COG1169	isochorismate synthase
ABE28_RS01160	COG1021	2,3-dihydroxybenzoate-AMP ligase
ABE28_RS01165	COG1535	isochorismatase
ABE28_RS01165	COG3433	isochorismatase activity
ABE28_RS01170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABE28_RS01175	COG3251	PFAM MbtH domain protein
ABE28_RS01180	COG0477	Major facilitator Superfamily
ABE28_RS01190	COG2814	Major facilitator Superfamily
ABE28_RS01200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABE28_RS01215	COG2814	Major facilitator Superfamily
ABE28_RS01220	COG1846	Transcriptional regulator
ABE28_RS01225	COG2822	iron ion transport
ABE28_RS01230	COG2837	iron assimilation
ABE28_RS01235	COG0672	)-iron permease
ABE28_RS01240	COG0789	Transcriptional regulator
ABE28_RS01245	COG1253	flavin adenine dinucleotide binding
ABE28_RS01250	COG2205	protein histidine kinase activity
ABE28_RS01250	COG0784	Response regulator, receiver
ABE28_RS01250	COG2198	Histidine kinase
ABE28_RS01255	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABE28_RS01260	COG2208	phosphoserine phosphatase activity
ABE28_RS01300	COG4974	Belongs to the 'phage' integrase family
ABE28_RS01305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABE28_RS01310	COG1309	transcriptional regulator
ABE28_RS01315	COG1597	lipid kinase activity
ABE28_RS01345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABE28_RS01355	COG0513	Belongs to the DEAD box helicase family
ABE28_RS01360	COG3402	PFAM membrane-flanked domain
ABE28_RS01365	COG3428	Bacterial PH domain
ABE28_RS01370	COG0705	Rhomboid family
ABE28_RS01375	COG0736	holo-[acyl-carrier-protein] synthase activity
ABE28_RS01380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABE28_RS01390	COG0864	Transcriptional regulator
ABE28_RS01395	COG2337	Toxic component of a toxin-antitoxin (TA) module
ABE28_RS01400	COG1366	Belongs to the anti-sigma-factor antagonist family
ABE28_RS01405	COG1366	Belongs to the anti-sigma-factor antagonist family
ABE28_RS01410	COG2172	sigma factor antagonist activity
ABE28_RS01415	COG2208	phosphoserine phosphatase activity
ABE28_RS01420	COG1366	Belongs to the anti-sigma-factor antagonist family
ABE28_RS01425	COG2172	sigma factor antagonist activity
ABE28_RS01430	COG1191	sigma factor activity
ABE28_RS01435	COG2208	phosphoserine phosphatase activity
ABE28_RS01440	COG2183	response to ionizing radiation
ABE28_RS01445	COG3091	SprT-like family
ABE28_RS01525	COG0802	atpase or kinase
ABE28_RS01530	COG1214	PFAM Peptidase M22, glycoprotease
ABE28_RS01535	COG0456	acetyltransferase
ABE28_RS01545	COG0488	(ABC) transporter
ABE28_RS01550	COG0315	cyclic pyranopterin monophosphate synthase activity
ABE28_RS01555	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ABE28_RS01565	COG1266	CAAX protease self-immunity
ABE28_RS01575	COG0459	protein refolding
ABE28_RS01600	COG4948	Mandelate Racemase Muconate Lactonizing
ABE28_RS01615	COG0693	protein deglycase activity
ABE28_RS01625	COG0784	Response regulator, receiver
ABE28_RS01625	COG2205	protein histidine kinase activity
ABE28_RS01625	COG2198	Histidine kinase
ABE28_RS01640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABE28_RS01645	COG3395	kinase activity
ABE28_RS01650	COG1349	DNA-binding transcription factor activity
ABE28_RS01655	COG1802	Transcriptional regulator
ABE28_RS01660	COG1070	Carbohydrate kinase
ABE28_RS01670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ABE28_RS01680	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABE28_RS01685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS01690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS01695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS01705	COG2986	histidine ammonia-lyase
ABE28_RS01710	COG0833	amino acid
ABE28_RS01720	COG4175	Glycine betaine
ABE28_RS01720	COG0517	IMP dehydrogenase activity
ABE28_RS01725	COG2113	Glycine betaine
ABE28_RS01740	COG4842	Belongs to the WXG100 family
ABE28_RS01750	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABE28_RS01755	COG1674	ftsk spoiiie
ABE28_RS01760	COG1511	domain protein
ABE28_RS01775	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS01785	COG0714	Associated with various cellular activities
ABE28_RS01790	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
ABE28_RS01795	COG1305	Transglutaminase-like
ABE28_RS01800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABE28_RS01800	COG0519	Catalyzes the synthesis of GMP from XMP
ABE28_RS01805	COG2252	PERMEase
ABE28_RS01810	COG3711	transcriptional antiterminator
ABE28_RS01815	COG2190	(PTS) system
ABE28_RS01815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS01815	COG1263	PTS System
ABE28_RS01835	COG2814	Major facilitator Superfamily
ABE28_RS01845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ABE28_RS01850	COG2814	Major facilitator Superfamily
ABE28_RS01855	COG1609	Transcriptional regulator
ABE28_RS01860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ABE28_RS01885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABE28_RS01890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABE28_RS01895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABE28_RS01905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABE28_RS01910	COG0047	phosphoribosylformylglycinamidine synthase activity
ABE28_RS01920	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABE28_RS01925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABE28_RS01930	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABE28_RS01940	COG0151	Belongs to the GarS family
ABE28_RS01955	COG1470	cell adhesion involved in biofilm formation
ABE28_RS01960	COG4496	protein, YerC YecD
ABE28_RS01965	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ABE28_RS01970	COG0210	DNA helicase
ABE28_RS01975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABE28_RS01980	COG4851	CamS sex pheromone cAM373 precursor
ABE28_RS01985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABE28_RS01990	COG0154	amidase activity
ABE28_RS01995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABE28_RS02000	COG1595	DNA-templated transcription, initiation
ABE28_RS02020	COG1597	lipid kinase activity
ABE28_RS02025	COG0454	-acetyltransferase
ABE28_RS02035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABE28_RS02040	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS02045	COG2323	membrane
ABE28_RS02055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABE28_RS02085	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
ABE28_RS02090	COG3853	Toxic anion resistance protein (TelA)
ABE28_RS02095	COG0778	Nitroreductase
ABE28_RS02100	COG0653	protein targeting
ABE28_RS02105	COG1404	Belongs to the peptidase S8 family
ABE28_RS02110	COG4549	nuclear export factor GLE1
ABE28_RS02115	COG2372	response to copper ion
ABE28_RS02115	COG1276	copper resistance
ABE28_RS02125	COG5002	protein histidine kinase activity
ABE28_RS02130	COG0398	Pfam SNARE associated Golgi protein
ABE28_RS02135	COG4708	membrane
ABE28_RS02140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABE28_RS02155	COG2234	aminopeptidase activity
ABE28_RS02170	COG5444	nuclease activity
ABE28_RS02185	COG2733	membrane
ABE28_RS02190	COG0385	Bile acid
ABE28_RS02195	COG0745	RESPONSE REGULATOR receiver
ABE28_RS02205	COG0577	efflux transmembrane transporter activity
ABE28_RS02210	COG1136	(ABC) transporter
ABE28_RS02215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS02240	COG1609	Transcriptional regulator
ABE28_RS02250	COG0673	inositol 2-dehydrogenase activity
ABE28_RS02255	COG0673	inositol 2-dehydrogenase activity
ABE28_RS02265	COG1187	pseudouridine synthase activity
ABE28_RS02270	COG0667	Aldo Keto reductase
ABE28_RS02285	COG1129	ABC transporter
ABE28_RS02290	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABE28_RS02305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABE28_RS02315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABE28_RS02320	COG1845	cytochrome c oxidase, subunit III
ABE28_RS02325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABE28_RS02340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ABE28_RS02345	COG0527	aspartate kinase activity
ABE28_RS02350	COG4585	Histidine kinase
ABE28_RS02355	COG2197	response regulator
ABE28_RS02360	COG1131	(ABC) transporter
ABE28_RS02365	COG1511	domain protein
ABE28_RS02365	COG0842	Transport permease protein
ABE28_RS02370	COG0842	Transport permease protein
ABE28_RS02375	COG0778	Nitroreductase
ABE28_RS02380	COG1132	(ABC) transporter
ABE28_RS02385	COG1132	(ABC) transporter
ABE28_RS02390	COG1309	transcriptional regulator
ABE28_RS02395	COG2814	Major facilitator Superfamily
ABE28_RS02405	COG1966	Carbon starvation protein
ABE28_RS02415	COG0004	ammonium transporteR
ABE28_RS02420	COG0347	Belongs to the P(II) protein family
ABE28_RS02430	COG3279	Response regulator of the LytR AlgR family
ABE28_RS02435	COG0427	acetyl-CoA hydrolase
ABE28_RS02440	COG0628	permease
ABE28_RS02445	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS02450	COG1301	dicarboxylic acid transport
ABE28_RS02455	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABE28_RS02460	COG1388	LysM domain
ABE28_RS02460	COG3584	3D domain protein
ABE28_RS02465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABE28_RS02470	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ABE28_RS02475	COG0840	transmembrane signaling receptor activity
ABE28_RS02490	COG2027	D-alanyl-D-alanine carboxypeptidase
ABE28_RS02495	COG0546	phosphoglycolate phosphatase activity
ABE28_RS02510	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABE28_RS02520	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS02525	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS02530	COG0243	molybdopterin cofactor binding
ABE28_RS02535	COG4191	Histidine kinase
ABE28_RS02540	COG0513	Belongs to the DEAD box helicase family
ABE28_RS02545	COG2801	Transposase and inactivated derivatives
ABE28_RS02555	COG1846	Transcriptional regulator
ABE28_RS02560	COG2153	protein acetylation
ABE28_RS02565	COG2364	Membrane
ABE28_RS02570	COG0626	cystathionine gamma-synthase activity
ABE28_RS02580	COG0307	riboflavin synthase, alpha
ABE28_RS02585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABE28_RS02585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABE28_RS02595	COG2404	hydrolase activity, acting on ester bonds
ABE28_RS02600	COG1295	ribonuclease BN
ABE28_RS02615	COG1562	ergosterol biosynthetic process
ABE28_RS02650	COG0475	glutathione-regulated potassium exporter activity
ABE28_RS02655	COG0490	domain, Protein
ABE28_RS02660	COG0582	viral genome integration into host DNA
ABE28_RS02665	COG1077	Cell shape determining protein MreB Mrl
ABE28_RS02670	COG3180	Ammonia monooxygenase
ABE28_RS02675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ABE28_RS02680	COG1360	Flagellar Motor Protein
ABE28_RS02690	COG0693	protein deglycase activity
ABE28_RS02695	COG0024	Methionine aminopeptidase
ABE28_RS02700	COG1763	Mo-molybdopterin cofactor biosynthetic process
ABE28_RS02705	COG0303	'Molybdopterin
ABE28_RS02710	COG4840	Belongs to the UPF0435 family
ABE28_RS02720	COG1295	ribonuclease BN
ABE28_RS02725	COG2217	Heavy metal translocating P-type atpase
ABE28_RS02730	COG0477	Major facilitator Superfamily
ABE28_RS02735	COG0387	Pfam Sodium calcium exchanger
ABE28_RS02745	COG0535	radical SAM domain protein
ABE28_RS02775	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABE28_RS02780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABE28_RS02785	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABE28_RS02790	COG4807	Protein conserved in bacteria
ABE28_RS02795	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS02805	COG1288	antiporter activity
ABE28_RS02810	COG1473	amidohydrolase
ABE28_RS02815	COG0840	transmembrane signaling receptor activity
ABE28_RS02825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS02830	COG0765	amino acid transport
ABE28_RS02845	COG1940	carbohydrate kinase activity
ABE28_RS02850	COG1840	ABC-type Fe3 transport system, periplasmic component
ABE28_RS02855	COG3842	ATPase activity
ABE28_RS02865	COG0165	Argininosuccinate lyase
ABE28_RS02870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABE28_RS02880	COG1113	amino acid transport
ABE28_RS02885	COG1113	amino acid transport
ABE28_RS02890	COG0489	protein tyrosine kinase activity
ABE28_RS02895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABE28_RS02910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABE28_RS02915	COG0303	'Molybdopterin
ABE28_RS02920	COG0314	molybdopterin synthase activity
ABE28_RS02925	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABE28_RS02930	COG3383	formate dehydrogenase (NAD+) activity
ABE28_RS02935	COG2427	Protein of unknown function (DUF1641)
ABE28_RS02940	COG3223	Belongs to the PsiE family
ABE28_RS02945	COG5609	conserved protein (DUF2294)
ABE28_RS02955	COG4149	molybdate abc transporter
ABE28_RS02965	COG3383	formate dehydrogenase (NAD+) activity
ABE28_RS02980	COG0583	DNA-binding transcription factor activity
ABE28_RS02985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS02990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS02995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABE28_RS03000	COG0456	acetyltransferase
ABE28_RS03005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS03010	COG0765	amino acid transport
ABE28_RS03015	COG0765	amino acid transport
ABE28_RS03020	COG1126	abc transporter atp-binding protein
ABE28_RS03030	COG1473	amidohydrolase
ABE28_RS03035	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS03050	COG2271	Major facilitator Superfamily
ABE28_RS03055	COG0156	8-amino-7-oxononanoate synthase activity
ABE28_RS03060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABE28_RS03065	COG1113	amino acid transport
ABE28_RS03115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABE28_RS03125	COG0305	Participates in initiation and elongation during chromosome replication
ABE28_RS03195	COG0740	serine-type endopeptidase activity
ABE28_RS03235	COG3953	SLT domain
ABE28_RS03235	COG5412	phage tail tape measure protein
ABE28_RS03320	COG3069	C4-dicarboxylate transmembrane transporter activity
ABE28_RS03330	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS03350	COG1136	(ABC) transporter
ABE28_RS03355	COG0577	efflux transmembrane transporter activity
ABE28_RS03365	COG2205	protein histidine kinase activity
ABE28_RS03370	COG0745	RESPONSE REGULATOR receiver
ABE28_RS03375	COG1126	abc transporter atp-binding protein
ABE28_RS03380	COG0765	amino acid transport
ABE28_RS03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS03415	COG2508	Transcriptional regulator
ABE28_RS03420	COG2508	Transcriptional regulator
ABE28_RS03425	COG3195	allantoin biosynthetic process
ABE28_RS03425	COG3648	Uricase
ABE28_RS03430	COG3648	Uricase
ABE28_RS03430	COG3195	allantoin biosynthetic process
ABE28_RS03435	COG2351	hydroxyisourate hydrolase activity
ABE28_RS03440	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABE28_RS03460	COG0791	NLP P60 protein
ABE28_RS03460	COG1388	LysM domain
ABE28_RS03475	COG1695	Transcriptional regulator
ABE28_RS03490	COG0385	Bile acid
ABE28_RS03495	COG2814	Major facilitator Superfamily
ABE28_RS03520	COG0166	Belongs to the GPI family
ABE28_RS03525	COG0628	permease
ABE28_RS03535	COG0765	amino acid transport
ABE28_RS03540	COG1126	abc transporter atp-binding protein
ABE28_RS03550	COG0583	DNA-binding transcription factor activity
ABE28_RS03570	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS03575	COG0183	Belongs to the thiolase family
ABE28_RS03595	COG1090	epimerase
ABE28_RS03620	COG1988	membrane-bound metal-dependent
ABE28_RS03625	COG1194	a g-specific adenine glycosylase
ABE28_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS03655	COG3557	Belongs to the UPF0374 family
ABE28_RS03660	COG1132	(ABC) transporter
ABE28_RS03665	COG0697	spore germination
ABE28_RS03675	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABE28_RS03680	COG2814	Major facilitator Superfamily
ABE28_RS03685	COG1566	PFAM secretion protein HlyD family protein
ABE28_RS03690	COG1846	Transcriptional regulator
ABE28_RS03695	COG4129	membrane
ABE28_RS03700	COG0067	glutamate synthase
ABE28_RS03700	COG0070	glutamate synthase
ABE28_RS03700	COG0069	glutamate synthase activity
ABE28_RS03705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABE28_RS03715	COG4555	ABC transporter
ABE28_RS03725	COG4451	ribulose bisphosphate carboxylase, small
ABE28_RS03725	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABE28_RS03735	COG0582	viral genome integration into host DNA
ABE28_RS03755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABE28_RS03765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABE28_RS03770	COG2205	protein histidine kinase activity
ABE28_RS03775	COG0584	glycerophosphoryl diester phosphodiesterase
ABE28_RS03780	COG1063	alcohol dehydrogenase
ABE28_RS03805	COG1011	Hydrolase
ABE28_RS03810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABE28_RS03820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABE28_RS03855	COG1388	LysM domain
ABE28_RS03910	COG1904	glucuronate isomerase
ABE28_RS03915	COG3250	beta-galactosidase activity
ABE28_RS03930	COG0673	inositol 2-dehydrogenase activity
ABE28_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS03950	COG0697	spore germination
ABE28_RS03965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABE28_RS03970	COG2610	gluconate transmembrane transporter activity
ABE28_RS03985	COG2329	Antibiotic biosynthesis monooxygenase
ABE28_RS04005	COG1309	transcriptional regulator
ABE28_RS04010	COG0477	Major facilitator Superfamily
ABE28_RS04020	COG1902	pentaerythritol trinitrate reductase activity
ABE28_RS04055	COG0501	Belongs to the peptidase M48B family
ABE28_RS04060	COG2259	Doxx family
ABE28_RS04075	COG0579	oxidoreductase
ABE28_RS04090	COG0488	(ABC) transporter
ABE28_RS04095	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS04105	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABE28_RS04110	COG1802	Transcriptional regulator
ABE28_RS04115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS04125	COG2267	carboxylic ester hydrolase activity
ABE28_RS04130	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS04135	COG0431	NADPH-dependent FMN reductase
ABE28_RS04140	COG0196	riboflavin kinase activity
ABE28_RS04145	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS04155	COG1535	isochorismatase
ABE28_RS04155	COG3433	isochorismatase activity
ABE28_RS04160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABE28_RS04165	COG0583	DNA-binding transcription factor activity
ABE28_RS04170	COG3180	Ammonia monooxygenase
ABE28_RS04180	COG2851	Citrate transporter
ABE28_RS04185	COG0583	DNA-binding transcription factor activity
ABE28_RS04190	COG2828	Protein conserved in bacteria
ABE28_RS04195	COG0028	Belongs to the TPP enzyme family
ABE28_RS04200	COG2223	nitrite transmembrane transporter activity
ABE28_RS04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS04240	COG0601	transmembrane transport
ABE28_RS04255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABE28_RS04265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABE28_RS04275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ABE28_RS04285	COG0697	spore germination
ABE28_RS04310	COG0667	Aldo Keto reductase
ABE28_RS04320	COG2351	hydroxyisourate hydrolase activity
ABE28_RS04325	COG0745	RESPONSE REGULATOR receiver
ABE28_RS04330	COG5002	protein histidine kinase activity
ABE28_RS04355	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABE28_RS04385	COG2723	6-phospho-beta-galactosidase activity
ABE28_RS04390	COG1263	PTS System
ABE28_RS04390	COG2190	(PTS) system
ABE28_RS04390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS04395	COG3711	transcriptional antiterminator
ABE28_RS04435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABE28_RS04440	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS04445	COG0124	histidyl-tRNA synthetase
ABE28_RS04450	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS04455	COG2084	Dehydrogenase
ABE28_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS04465	COG1024	Enoyl-CoA hydratase
ABE28_RS04470	COG1024	Enoyl-CoA hydratase
ABE28_RS04475	COG0346	lactoylglutathione lyase activity
ABE28_RS04485	COG0791	NLP P60 protein
ABE28_RS04485	COG3103	Sh3 type 3 domain protein
ABE28_RS04485	COG1388	LysM domain
ABE28_RS04490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABE28_RS04500	COG0697	spore germination
ABE28_RS04510	COG3689	TIGRFAM TIGR03943 family protein
ABE28_RS04515	COG0701	Predicted permease
ABE28_RS04530	COG2130	NADP-dependent
ABE28_RS04545	COG3382	B3 4 domain protein
ABE28_RS04550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABE28_RS04560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABE28_RS04565	COG0778	Nitroreductase
ABE28_RS04570	COG1120	ATPase activity
ABE28_RS04575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS04580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS04585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS04590	COG2766	serine protein kinase
ABE28_RS04630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABE28_RS04640	COG3944	biosynthesis protein
ABE28_RS04645	COG0489	protein tyrosine kinase activity
ABE28_RS04685	COG2807	transmembrane transport
ABE28_RS04705	COG0531	amino acid
ABE28_RS04740	COG3961	Belongs to the TPP enzyme family
ABE28_RS04760	COG0586	Pfam SNARE associated Golgi protein
ABE28_RS04765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ABE28_RS04770	COG2094	Belongs to the DNA glycosylase MPG family
ABE28_RS04775	COG0477	Major facilitator Superfamily
ABE28_RS04780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABE28_RS04785	COG0277	FAD linked oxidase domain protein
ABE28_RS04790	COG0686	Belongs to the AlaDH PNT family
ABE28_RS04795	COG2217	Heavy metal translocating P-type atpase
ABE28_RS04800	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABE28_RS04800	COG2508	Transcriptional regulator
ABE28_RS04805	COG0306	phosphate transporter
ABE28_RS04810	COG1392	Phosphate transport regulator
ABE28_RS04815	COG0306	phosphate transporter
ABE28_RS04820	COG0656	L-ascorbic acid biosynthetic process
ABE28_RS04825	COG2261	transglycosylase associated protein
ABE28_RS04830	COG0277	FAD linked oxidase domain protein
ABE28_RS04835	COG0564	pseudouridine synthase activity
ABE28_RS04845	COG3118	belongs to the thioredoxin family
ABE28_RS04850	COG3153	acetyltransferase
ABE28_RS04850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABE28_RS04855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABE28_RS04880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABE28_RS04890	COG1473	amidohydrolase
ABE28_RS04900	COG2719	SpoVR family
ABE28_RS04905	COG2814	Major facilitator Superfamily
ABE28_RS04910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABE28_RS04915	COG0784	Response regulator, receiver
ABE28_RS04915	COG3437	response regulator, receiver
ABE28_RS04925	COG0398	Pfam SNARE associated Golgi protein
ABE28_RS04930	COG0745	RESPONSE REGULATOR receiver
ABE28_RS04935	COG5002	protein histidine kinase activity
ABE28_RS04955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABE28_RS04960	COG2059	Chromate
ABE28_RS04965	COG2059	Chromate
ABE28_RS04975	COG2271	Major facilitator Superfamily
ABE28_RS04980	COG0191	fructose-bisphosphate aldolase activity
ABE28_RS04985	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABE28_RS04990	COG2186	Transcriptional regulator
ABE28_RS05005	COG1414	Transcriptional regulator
ABE28_RS05010	COG3959	Transketolase, thiamine diphosphate binding domain
ABE28_RS05015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABE28_RS05025	COG3960	tartronate-semialdehyde synthase activity
ABE28_RS05040	COG2508	Transcriptional regulator
ABE28_RS05045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABE28_RS05050	COG3257	ureidoglycine aminohydrolase activity
ABE28_RS05060	COG2233	PERMEase
ABE28_RS05065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABE28_RS05080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABE28_RS05090	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ABE28_RS05095	COG3396	Phenylacetate-CoA oxygenase
ABE28_RS05120	COG1024	Enoyl-CoA hydratase
ABE28_RS05125	COG1024	Enoyl-CoA hydratase
ABE28_RS05130	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS05135	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS05140	COG0183	Belongs to the thiolase family
ABE28_RS05145	COG1024	Enoyl-CoA hydratase
ABE28_RS05150	COG3327	negative regulation of DNA-templated transcription, initiation
ABE28_RS05165	COG0586	Pfam SNARE associated Golgi protein
ABE28_RS05180	COG0745	RESPONSE REGULATOR receiver
ABE28_RS05185	COG5002	protein histidine kinase activity
ABE28_RS05190	COG1393	Belongs to the ArsC family
ABE28_RS05195	COG4149	molybdate abc transporter
ABE28_RS05205	COG1278	Cold shock
ABE28_RS05210	COG0716	FMN binding
ABE28_RS05215	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABE28_RS05220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABE28_RS05225	COG1227	inorganic diphosphatase activity
ABE28_RS05250	COG2814	Major facilitator Superfamily
ABE28_RS05255	COG2851	Citrate transporter
ABE28_RS05265	COG1054	Belongs to the UPF0176 family
ABE28_RS05275	COG0456	acetyltransferase
ABE28_RS05280	COG0671	phosphoesterase, PA-phosphatase related
ABE28_RS05285	COG0772	Belongs to the SEDS family
ABE28_RS05290	COG3339	Conserved Protein
ABE28_RS05295	COG1316	TRANSCRIPTIONal
ABE28_RS05310	COG0628	permease
ABE28_RS05320	COG1253	flavin adenine dinucleotide binding
ABE28_RS05325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS05335	COG0586	Pfam SNARE associated Golgi protein
ABE28_RS05340	COG1253	flavin adenine dinucleotide binding
ABE28_RS05345	COG3852	Histidine kinase
ABE28_RS05350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABE28_RS05355	COG0589	response to stress
ABE28_RS05360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABE28_RS05370	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ABE28_RS05395	COG1113	amino acid transport
ABE28_RS05400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABE28_RS05405	COG1522	sequence-specific DNA binding
ABE28_RS05415	COG1522	sequence-specific DNA binding
ABE28_RS05420	COG1595	DNA-templated transcription, initiation
ABE28_RS05435	COG0393	Putative heavy-metal-binding
ABE28_RS05440	COG0386	Belongs to the glutathione peroxidase family
ABE28_RS05445	COG0753	catalase activity
ABE28_RS05450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABE28_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS05475	COG0517	IMP dehydrogenase activity
ABE28_RS05475	COG0516	GMP reductase activity
ABE28_RS05480	COG0768	penicillin binding
ABE28_RS05495	COG1132	(ABC) transporter
ABE28_RS05500	COG1132	(ABC) transporter
ABE28_RS05505	COG0254	rRNA binding
ABE28_RS05510	COG0626	cystathionine gamma-synthase activity
ABE28_RS05515	COG0626	cystathionine gamma-synthase activity
ABE28_RS05520	COG0114	fumarate hydratase activity
ABE28_RS05530	COG3842	ATPase activity
ABE28_RS05535	COG2508	Transcriptional regulator
ABE28_RS05540	COG0371	Dehydrogenase
ABE28_RS05545	COG1464	Belongs to the NlpA lipoprotein family
ABE28_RS05550	COG2011	ABC-type metal ion transport system permease component
ABE28_RS05555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABE28_RS05580	COG0189	ligase activity
ABE28_RS05585	COG0189	ligase activity
ABE28_RS05590	COG0189	ligase activity
ABE28_RS05600	COG3679	Belongs to the UPF0342 family
ABE28_RS05605	COG0561	phosphatase activity
ABE28_RS05625	COG1834	amidinotransferase
ABE28_RS05630	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS05635	COG1024	Enoyl-CoA hydratase
ABE28_RS05645	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABE28_RS05650	COG0420	3'-5' exonuclease activity
ABE28_RS05655	COG4717	serine-type aminopeptidase activity
ABE28_RS05665	COG1120	ATPase activity
ABE28_RS05675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABE28_RS05685	COG0069	glutamate synthase activity
ABE28_RS05700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABE28_RS05725	COG1846	Transcriptional regulator
ABE28_RS05730	COG4980	gas vesicle protein
ABE28_RS05750	COG0537	adenosine 5'-monophosphoramidase activity
ABE28_RS05755	COG1131	(ABC) transporter
ABE28_RS05760	COG4473	ABC transporter
ABE28_RS05770	COG1473	amidohydrolase
ABE28_RS05780	COG2329	Antibiotic biosynthesis monooxygenase
ABE28_RS05785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ABE28_RS05790	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ABE28_RS05795	COG1309	transcriptional regulator
ABE28_RS05805	COG1234	tRNA 3'-trailer cleavage
ABE28_RS05810	COG0095	Lipoate-protein ligase
ABE28_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS05820	COG1418	mRNA catabolic process
ABE28_RS05825	COG2197	response regulator
ABE28_RS05830	COG0501	Belongs to the peptidase M48B family
ABE28_RS05835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS05845	COG4903	ComK protein
ABE28_RS05855	COG0398	Pfam SNARE associated Golgi protein
ABE28_RS05865	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ABE28_RS05870	COG1074	ATP-dependent DNA helicase activity
ABE28_RS05905	COG2271	Major facilitator Superfamily
ABE28_RS05910	COG2311	Membrane
ABE28_RS05925	COG0367	asparagine synthase
ABE28_RS05935	COG2182	Extracellular solute-binding protein
ABE28_RS05945	COG0366	Alpha amylase catalytic
ABE28_RS05950	COG1609	Transcriptional regulator
ABE28_RS05955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS05960	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS05965	COG1666	GTP binding
ABE28_RS05970	COG1307	EDD domain protein, DegV family
ABE28_RS05975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS05980	COG3729	General stress protein
ABE28_RS05995	COG0561	phosphatase activity
ABE28_RS06000	COG1073	alpha beta
ABE28_RS06005	COG2151	metal-sulfur cluster biosynthetic enzyme
ABE28_RS06010	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABE28_RS06015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABE28_RS06020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ABE28_RS06025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABE28_RS06030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ABE28_RS06040	COG0505	Belongs to the CarA family
ABE28_RS06050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABE28_RS06060	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABE28_RS06075	COG2267	carboxylic ester hydrolase activity
ABE28_RS06095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABE28_RS06100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ABE28_RS06105	COG5504	Zn-dependent protease
ABE28_RS06115	COG0180	Tryptophanyl-tRNA synthetase
ABE28_RS06130	COG0456	acetyltransferase
ABE28_RS06140	COG1393	Belongs to the ArsC family
ABE28_RS06145	COG4862	establishment of competence for transformation
ABE28_RS06150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABE28_RS06155	COG4469	Competence protein
ABE28_RS06160	COG1164	Oligoendopeptidase f
ABE28_RS06175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABE28_RS06180	COG2346	COG2346, Truncated hemoglobins
ABE28_RS06185	COG0741	lytic transglycosylase activity
ABE28_RS06190	COG4116	CYTH
ABE28_RS06195	COG2357	RelA SpoT domain protein
ABE28_RS06205	COG0564	pseudouridine synthase activity
ABE28_RS06210	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABE28_RS06215	COG2239	Acts as a magnesium transporter
ABE28_RS06220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ABE28_RS06225	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS06255	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABE28_RS06270	COG0210	DNA helicase
ABE28_RS06290	COG2153	protein acetylation
ABE28_RS06295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABE28_RS06300	COG2382	esterase
ABE28_RS06305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABE28_RS06325	COG3655	Transcriptional regulator
ABE28_RS06350	COG0693	protein deglycase activity
ABE28_RS06360	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABE28_RS06365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABE28_RS06370	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS06385	COG5337	Spore coat protein CotH
ABE28_RS06395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS06400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABE28_RS06405	COG2814	Major facilitator Superfamily
ABE28_RS06410	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS06415	COG0673	inositol 2-dehydrogenase activity
ABE28_RS06425	COG1902	pentaerythritol trinitrate reductase activity
ABE28_RS06430	COG1609	Transcriptional regulator
ABE28_RS06435	COG0366	Alpha amylase catalytic
ABE28_RS06440	COG1653	transport
ABE28_RS06445	COG1175	transmembrane transport
ABE28_RS06450	COG0395	ABC-type sugar transport system, permease component
ABE28_RS06455	COG1063	alcohol dehydrogenase
ABE28_RS06460	COG1082	Xylose isomerase domain protein TIM barrel
ABE28_RS06465	COG0673	inositol 2-dehydrogenase activity
ABE28_RS06470	COG1554	hydrolase, family 65, central catalytic
ABE28_RS06475	COG1929	Belongs to the glycerate kinase type-1 family
ABE28_RS06480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABE28_RS06485	COG0659	secondary active sulfate transmembrane transporter activity
ABE28_RS06490	COG0789	Transcriptional regulator
ABE28_RS06495	COG2272	Belongs to the type-B carboxylesterase lipase family
ABE28_RS06500	COG1113	amino acid transport
ABE28_RS06505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABE28_RS06510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABE28_RS06520	COG4208	sulfate ABC transporter
ABE28_RS06530	COG0791	NLP P60 protein
ABE28_RS06530	COG3883	PFAM NLP P60 protein
ABE28_RS06545	COG2017	converts alpha-aldose to the beta-anomer
ABE28_RS06550	COG0531	amino acid
ABE28_RS06555	COG5583	Uncharacterized small protein (DUF2292)
ABE28_RS06560	COG2367	Beta-lactamase
ABE28_RS06575	COG1278	Cold shock
ABE28_RS06585	COG2309	aminopeptidase activity
ABE28_RS06590	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS06595	COG0477	Major facilitator Superfamily
ABE28_RS06600	COG0352	thiamine-phosphate diphosphorylase activity
ABE28_RS06605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ABE28_RS06610	COG0352	thiamine-phosphate diphosphorylase activity
ABE28_RS06610	COG0351	phosphomethylpyrimidine kinase
ABE28_RS06620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABE28_RS06635	COG1247	-acetyltransferase
ABE28_RS06645	COG1132	(ABC) transporter
ABE28_RS06650	COG2318	DinB family
ABE28_RS06655	COG1876	peptidase activity
ABE28_RS06660	COG1607	acyl-coa hydrolase
ABE28_RS06665	COG0670	Belongs to the BI1 family
ABE28_RS06675	COG4608	Belongs to the ABC transporter superfamily
ABE28_RS06680	COG0601	transmembrane transport
ABE28_RS06685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS06700	COG1363	Peptidase, m42
ABE28_RS06705	COG3871	stress protein (general stress protein 26)
ABE28_RS06715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABE28_RS06715	COG1181	Belongs to the D-alanine--D-alanine ligase family
ABE28_RS06735	COG0584	glycerophosphoryl diester phosphodiesterase
ABE28_RS06745	COG1764	response to oxidative stress
ABE28_RS06750	COG1725	Transcriptional regulator
ABE28_RS06755	COG1131	(ABC) transporter
ABE28_RS06770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABE28_RS06775	COG1757	Na H antiporter
ABE28_RS06780	COG0772	Belongs to the SEDS family
ABE28_RS06785	COG3320	Male sterility
ABE28_RS06785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABE28_RS06795	COG0861	Integral membrane protein TerC family
ABE28_RS06800	COG1191	sigma factor activity
ABE28_RS06815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABE28_RS06820	COG3852	Histidine kinase
ABE28_RS06825	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS06835	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS06845	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS06850	COG1024	Enoyl-CoA hydratase
ABE28_RS06865	COG2045	Belongs to the ComB family
ABE28_RS06870	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS06875	COG1024	Enoyl-CoA hydratase
ABE28_RS06895	COG3594	Acyltransferase
ABE28_RS06900	COG5002	protein histidine kinase activity
ABE28_RS06915	COG2223	nitrite transmembrane transporter activity
ABE28_RS06920	COG3852	Histidine kinase
ABE28_RS06925	COG1846	Transcriptional regulator
ABE28_RS06930	COG1164	Oligoendopeptidase f
ABE28_RS06935	COG3949	Membrane
ABE28_RS06945	COG4873	Protein conserved in bacteria
ABE28_RS06965	COG1525	nuclease
ABE28_RS06970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABE28_RS06975	COG0390	transport system, permease component
ABE28_RS06985	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABE28_RS06995	COG2084	Dehydrogenase
ABE28_RS07005	COG0436	Aminotransferase
ABE28_RS07010	COG0598	Magnesium transport protein CorA
ABE28_RS07015	COG0784	Response regulator, receiver
ABE28_RS07015	COG0835	chemotaxis
ABE28_RS07030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABE28_RS07035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ABE28_RS07040	COG1408	metallophosphoesterase
ABE28_RS07045	COG0490	domain, Protein
ABE28_RS07045	COG0471	metal ion transport
ABE28_RS07050	COG2200	EAL domain
ABE28_RS07075	COG4703	Protein of unknown function (DUF1797)
ABE28_RS07090	COG0517	IMP dehydrogenase activity
ABE28_RS07095	COG0477	Major facilitator Superfamily
ABE28_RS07100	COG0583	DNA-binding transcription factor activity
ABE28_RS07105	COG2171	N-acyltransferase activity
ABE28_RS07110	COG1473	amidohydrolase
ABE28_RS07115	COG0569	domain protein
ABE28_RS07120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABE28_RS07125	COG5503	Protein of unknown function (DUF1447)
ABE28_RS07130	COG0561	phosphatase activity
ABE28_RS07140	COG0497	DNA recombination
ABE28_RS07150	COG0022	dehydrogenase e1 component
ABE28_RS07155	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABE28_RS07170	COG0726	polysaccharide deacetylase
ABE28_RS07180	COG1982	Orn Lys Arg decarboxylase major
ABE28_RS07190	COG4476	Belongs to the UPF0223 family
ABE28_RS07200	COG0512	Glutamine amidotransferase of anthranilate synthase
ABE28_RS07200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABE28_RS07230	COG4493	Belongs to the UPF0637 family
ABE28_RS07240	COG0483	inositol monophosphate 1-phosphatase activity
ABE28_RS07250	COG1217	gtp-binding protein TYPA
ABE28_RS07270	COG4896	Protein conserved in bacteria
ABE28_RS07280	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ABE28_RS07285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ABE28_RS07290	COG4838	Belongs to the UPF0358 family
ABE28_RS07295	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ABE28_RS07300	COG1612	heme a metabolic process
ABE28_RS07305	COG0109	protoheme IX farnesyltransferase activity
ABE28_RS07330	COG3336	cytochrome c oxidase
ABE28_RS07345	COG2340	Cysteine-rich secretory protein family
ABE28_RS07370	COG3679	Belongs to the UPF0342 family
ABE28_RS07380	COG4471	UPF0298 protein
ABE28_RS07395	COG0742	ribosomal rna small subunit methyltransferase
ABE28_RS07400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ABE28_RS07405	COG3314	Sporulation integral membrane protein YlbJ
ABE28_RS07410	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABE28_RS07415	COG3480	Lon protease (S16) C-terminal proteolytic domain
ABE28_RS07420	COG2801	Transposase and inactivated derivatives
ABE28_RS07430	COG1323	Belongs to the UPF0348 family
ABE28_RS07435	COG1399	metal-binding, possibly nucleic acid-binding protein
ABE28_RS07440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ABE28_RS07445	COG1024	Enoyl-CoA hydratase
ABE28_RS07455	COG0454	-acetyltransferase
ABE28_RS07460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABE28_RS07470	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ABE28_RS07475	COG2001	Belongs to the MraZ family
ABE28_RS07485	COG4839	cell division protein FtsL
ABE28_RS07490	COG0768	penicillin binding
ABE28_RS07495	COG0768	penicillin binding
ABE28_RS07500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABE28_RS07505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABE28_RS07510	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ABE28_RS07515	COG0772	Belongs to the SEDS family
ABE28_RS07520	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ABE28_RS07525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABE28_RS07530	COG0849	cell division
ABE28_RS07535	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABE28_RS07545	COG1191	sigma factor activity
ABE28_RS07550	COG1191	sigma factor activity
ABE28_RS07555	COG1873	PFAM PRC-barrel domain
ABE28_RS07560	COG1496	oxidoreductase activity
ABE28_RS07565	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABE28_RS07570	COG1799	cell septum assembly
ABE28_RS07575	COG0762	integral membrane protein
ABE28_RS07580	COG2302	S4 RNA-binding domain
ABE28_RS07585	COG3599	regulation of cell shape
ABE28_RS07595	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ABE28_RS07600	COG0564	pseudouridine synthase activity
ABE28_RS07605	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ABE28_RS07615	COG0540	Belongs to the ATCase OTCase family
ABE28_RS07620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ABE28_RS07625	COG0505	Belongs to the CarA family
ABE28_RS07630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ABE28_RS07640	COG0167	dihydroorotate dehydrogenase activity
ABE28_RS07645	COG0284	orotidine-5'-phosphate decarboxylase activity
ABE28_RS07650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABE28_RS07660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABE28_RS07665	COG1561	YicC-like family, N-terminal region
ABE28_RS07675	COG0194	GDP metabolic process
ABE28_RS07685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABE28_RS07690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABE28_RS07705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABE28_RS07705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABE28_RS07710	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABE28_RS07715	COG0631	protein serine/threonine phosphatase activity
ABE28_RS07720	COG0515	serine threonine protein kinase
ABE28_RS07720	COG2815	serine threonine protein kinase
ABE28_RS07725	COG1162	GTPase activity
ABE28_RS07730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABE28_RS07735	COG1564	THIamine pyrophosphokinase
ABE28_RS07745	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ABE28_RS07750	COG1302	Protein conserved in bacteria
ABE28_RS07755	COG1461	Dihydroxyacetone kinase
ABE28_RS07760	COG1760	l-serine dehydratase
ABE28_RS07765	COG1760	l-serine dehydratase
ABE28_RS07770	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABE28_RS07775	COG1349	DNA-binding transcription factor activity
ABE28_RS07785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABE28_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS07800	COG0571	ribonuclease III activity
ABE28_RS07805	COG1196	nuclear chromosome segregation
ABE28_RS07810	COG0552	protein localization to endoplasmic reticulum
ABE28_RS07825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABE28_RS07830	COG0228	four-way junction DNA binding
ABE28_RS07835	COG1837	Belongs to the UPF0109 family
ABE28_RS07845	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABE28_RS07850	COG0336	Belongs to the RNA methyltransferase TrmD family
ABE28_RS07855	COG0335	large ribosomal subunit rRNA binding
ABE28_RS07870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABE28_RS07880	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABE28_RS07885	COG0045	succinate-CoA ligase (ADP-forming) activity
ABE28_RS07890	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABE28_RS07895	COG0758	DNA mediated transformation
ABE28_RS07900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABE28_RS07905	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ABE28_RS07910	COG4974	Belongs to the 'phage' integrase family
ABE28_RS07920	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ABE28_RS07925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ABE28_RS07930	COG1815	bacterial-type flagellum-dependent cell motility
ABE28_RS07935	COG1558	bacterial-type flagellum-dependent cell motility
ABE28_RS07940	COG1677	Flagellar hook-basal body complex protein FliE
ABE28_RS07945	COG1766	The M ring may be actively involved in energy transduction
ABE28_RS07950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABE28_RS07960	COG1157	protein secretion by the type III secretion system
ABE28_RS07965	COG2882	bacterial-type flagellum organization
ABE28_RS07980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ABE28_RS07995	COG1582	Flagellar protein (FlbD)
ABE28_RS08000	COG1580	Controls the rotational direction of flagella during chemotaxis
ABE28_RS08005	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABE28_RS08010	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ABE28_RS08010	COG1776	CheC inhibitor of MCP methylation
ABE28_RS08015	COG2201	protein-glutamate methylesterase activity
ABE28_RS08020	COG3190	flagellar
ABE28_RS08025	COG1338	Plays a role in the flagellum-specific transport system
ABE28_RS08030	COG1987	bacterial-type flagellum assembly
ABE28_RS08035	COG1684	flagellar biosynthetic protein fliR
ABE28_RS08040	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABE28_RS08045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ABE28_RS08050	COG1419	protein localization to endoplasmic reticulum
ABE28_RS08055	COG0455	bacterial-type flagellum organization
ABE28_RS08060	COG2201	protein-glutamate methylesterase activity
ABE28_RS08065	COG0643	Histidine kinase
ABE28_RS08065	COG2198	Histidine kinase
ABE28_RS08075	COG1776	CheC inhibitor of MCP methylation
ABE28_RS08080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ABE28_RS08085	COG1191	sigma factor activity
ABE28_RS08105	COG0528	UMP kinase activity
ABE28_RS08120	COG4589	Belongs to the CDS family
ABE28_RS08125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ABE28_RS08130	COG0750	zinc metalloprotease
ABE28_RS08135	COG0442	prolyl-tRNA aminoacylation
ABE28_RS08140	COG2176	DNA-directed DNA polymerase activity
ABE28_RS08145	COG0779	Required for maturation of 30S ribosomal subunits
ABE28_RS08150	COG0195	Participates in both transcription termination and antitermination
ABE28_RS08155	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ABE28_RS08160	COG1358	cellular component organization or biogenesis
ABE28_RS08165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABE28_RS08170	COG1550	Protein conserved in bacteria
ABE28_RS08175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ABE28_RS08180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABE28_RS08185	COG0196	riboflavin kinase activity
ABE28_RS08195	COG1185	polyribonucleotide nucleotidyltransferase activity
ABE28_RS08200	COG0726	polysaccharide deacetylase
ABE28_RS08205	COG0612	Peptidase, M16
ABE28_RS08210	COG1873	PFAM PRC-barrel domain
ABE28_RS08215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABE28_RS08220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABE28_RS08225	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ABE28_RS08230	COG0527	aspartate kinase activity
ABE28_RS08235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABE28_RS08240	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ABE28_RS08245	COG0740	serine-type endopeptidase activity
ABE28_RS08255	COG1674	ftsk spoiiie
ABE28_RS08255	COG4980	gas vesicle protein
ABE28_RS08265	COG2188	Transcriptional regulator
ABE28_RS08270	COG1744	ABC transporter substrate-binding protein PnrA-like
ABE28_RS08275	COG3845	ABC transporter
ABE28_RS08280	COG4603	Belongs to the binding-protein-dependent transport system permease family
ABE28_RS08285	COG1079	Belongs to the binding-protein-dependent transport system permease family
ABE28_RS08290	COG0612	Peptidase, M16
ABE28_RS08295	COG0612	Peptidase, M16
ABE28_RS08300	COG0300	oxidoreductase activity
ABE28_RS08315	COG1426	Protein conserved in bacteria
ABE28_RS08320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABE28_RS08325	COG1546	Belongs to the CinA family
ABE28_RS08325	COG1058	Belongs to the CinA family
ABE28_RS08330	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ABE28_RS08340	COG1692	metallophosphoesterase
ABE28_RS08345	COG2359	stage V sporulation protein S
ABE28_RS08355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ABE28_RS08355	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABE28_RS08360	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABE28_RS08370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABE28_RS08375	COG4550	Control of competence regulator ComK, YlbF/YmcA
ABE28_RS08385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABE28_RS08395	COG1072	(Pantothenic acid kinase))
ABE28_RS08415	COG1473	amidohydrolase
ABE28_RS08420	COG1802	Transcriptional regulator
ABE28_RS08425	COG4948	Mandelate Racemase Muconate Lactonizing
ABE28_RS08430	COG2271	Major facilitator Superfamily
ABE28_RS08435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABE28_RS08450	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS08470	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABE28_RS08485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABE28_RS08515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS08525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABE28_RS08535	COG2814	Major facilitator Superfamily
ABE28_RS08545	COG0657	acetylesterase activity
ABE28_RS08550	COG2271	Major facilitator Superfamily
ABE28_RS08555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS08565	COG1473	amidohydrolase
ABE28_RS08570	COG2860	membrane
ABE28_RS08585	COG0716	FMN binding
ABE28_RS08615	COG1297	OPT oligopeptide transporter protein
ABE28_RS08625	COG3290	protein histidine kinase activity
ABE28_RS08625	COG3829	transcription factor binding
ABE28_RS08630	COG1288	antiporter activity
ABE28_RS08635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ABE28_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS08660	COG0367	asparagine synthase
ABE28_RS08665	COG2188	Transcriptional regulator
ABE28_RS08670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS08675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS08680	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABE28_RS08685	COG1486	melibiose metabolic process
ABE28_RS08695	COG1252	NADH dehydrogenase
ABE28_RS08715	COG3290	protein histidine kinase activity
ABE28_RS08720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ABE28_RS08725	COG1923	regulation of RNA biosynthetic process
ABE28_RS08730	COG0464	growth
ABE28_RS08735	COG2860	membrane
ABE28_RS08740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABE28_RS08745	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ABE28_RS08750	COG0789	Transcriptional regulator
ABE28_RS08755	COG0174	glutamine synthetase
ABE28_RS08830	COG3655	Transcriptional regulator
ABE28_RS08875	COG0629	single-stranded DNA binding
ABE28_RS09005	COG1388	LysM domain
ABE28_RS09005	COG1705	Flagellar rod assembly protein muramidase FlgJ
ABE28_RS09075	COG1876	peptidase activity
ABE28_RS09125	COG3935	DnaD domain protein
ABE28_RS09155	COG1595	DNA-templated transcription, initiation
ABE28_RS09185	COG2801	Transposase and inactivated derivatives
ABE28_RS09290	COG0658	competence protein
ABE28_RS09290	COG2333	competence protein COMEC
ABE28_RS09315	COG0305	Participates in initiation and elongation during chromosome replication
ABE28_RS09355	COG2801	Transposase and inactivated derivatives
ABE28_RS09395	COG0011	TIGRFAM Protein of
ABE28_RS09415	COG3655	Transcriptional regulator
ABE28_RS09420	COG3739	integral membrane protein
ABE28_RS09455	COG1473	amidohydrolase
ABE28_RS09465	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ABE28_RS09485	COG2364	Membrane
ABE28_RS09540	COG0861	Integral membrane protein TerC family
ABE28_RS09555	COG0823	Involved in the tonB-independent uptake of proteins
ABE28_RS09560	COG0577	efflux transmembrane transporter activity
ABE28_RS09565	COG1136	(ABC) transporter
ABE28_RS09570	COG5002	protein histidine kinase activity
ABE28_RS09575	COG0745	RESPONSE REGULATOR receiver
ABE28_RS09595	COG2197	response regulator
ABE28_RS09635	COG0789	Transcriptional regulator
ABE28_RS09650	COG0346	lactoylglutathione lyase activity
ABE28_RS09655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABE28_RS09665	COG2329	Antibiotic biosynthesis monooxygenase
ABE28_RS09680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABE28_RS09690	COG1309	transcriptional regulator
ABE28_RS09695	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS09700	COG0006	proline dipeptidase activity
ABE28_RS09730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS09745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS09750	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABE28_RS09760	COG4493	Belongs to the UPF0637 family
ABE28_RS09765	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS09775	COG0022	dehydrogenase e1 component
ABE28_RS09780	COG1252	NADH dehydrogenase
ABE28_RS09790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABE28_RS09795	COG2910	NAD(P)H-binding
ABE28_RS09800	COG1733	regulation of RNA biosynthetic process
ABE28_RS09815	COG2188	Transcriptional regulator
ABE28_RS09820	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS09840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABE28_RS09855	COG4335	DNA alkylation repair
ABE28_RS09860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS09860	COG1263	PTS System
ABE28_RS09865	COG0366	Alpha amylase catalytic
ABE28_RS09870	COG2188	Transcriptional regulator
ABE28_RS09875	COG2076	Multidrug Resistance protein
ABE28_RS09880	COG2076	Multidrug Resistance protein
ABE28_RS09885	COG0592	DNA-directed DNA polymerase activity
ABE28_RS09900	COG5002	protein histidine kinase activity
ABE28_RS09905	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABE28_RS09915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABE28_RS09940	COG1705	Flagellar rod assembly protein muramidase FlgJ
ABE28_RS09940	COG1388	LysM domain
ABE28_RS09945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ABE28_RS09950	COG1388	LysM domain
ABE28_RS09955	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABE28_RS09975	COG3763	UPF0154 protein
ABE28_RS09980	COG1714	RDD family
ABE28_RS09995	COG3118	belongs to the thioredoxin family
ABE28_RS10000	COG1902	pentaerythritol trinitrate reductase activity
ABE28_RS10005	COG2259	Doxx family
ABE28_RS10025	COG0785	Cytochrome C biogenesis protein
ABE28_RS10030	COG2201	protein-glutamate methylesterase activity
ABE28_RS10035	COG4846	Membrane protein involved in cytochrome C biogenesis
ABE28_RS10040	COG2391	methyltransferase activity
ABE28_RS10045	COG0425	Belongs to the sulfur carrier protein TusA family
ABE28_RS10065	COG0419	ATPase involved in DNA repair
ABE28_RS10080	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS10090	COG0183	Belongs to the thiolase family
ABE28_RS10100	COG0183	Belongs to the thiolase family
ABE28_RS10110	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS10120	COG1609	Transcriptional regulator
ABE28_RS10125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ABE28_RS10130	COG0738	Major facilitator superfamily
ABE28_RS10150	COG2210	Belongs to the sulfur carrier protein TusA family
ABE28_RS10160	COG0425	Belongs to the sulfur carrier protein TusA family
ABE28_RS10160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABE28_RS10165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABE28_RS10165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS10170	COG0425	Belongs to the sulfur carrier protein TusA family
ABE28_RS10175	COG0730	response to heat
ABE28_RS10180	COG1396	sequence-specific DNA binding
ABE28_RS10200	COG0778	Nitroreductase
ABE28_RS10210	COG0840	transmembrane signaling receptor activity
ABE28_RS10215	COG4152	abc transporter atp-binding protein
ABE28_RS10220	COG1668	transmembrane transport
ABE28_RS10235	COG3420	alginic acid biosynthetic process
ABE28_RS10255	COG1846	Transcriptional regulator
ABE28_RS10270	COG3706	GGDEF domain
ABE28_RS10290	COG0745	RESPONSE REGULATOR receiver
ABE28_RS10295	COG5002	protein histidine kinase activity
ABE28_RS10300	COG1705	Flagellar rod assembly protein muramidase FlgJ
ABE28_RS10305	COG1937	Protein conserved in bacteria
ABE28_RS10310	COG2608	mercury ion transmembrane transporter activity
ABE28_RS10315	COG2217	Heavy metal translocating P-type atpase
ABE28_RS10330	COG1131	(ABC) transporter
ABE28_RS10335	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ABE28_RS10340	COG0772	Belongs to the SEDS family
ABE28_RS10345	COG1309	transcriptional regulator
ABE28_RS10365	COG3540	Alkaline phosphatase
ABE28_RS10370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABE28_RS10375	COG0805	protein transport
ABE28_RS10385	COG1113	amino acid transport
ABE28_RS10390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABE28_RS10400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABE28_RS10420	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS10425	COG1846	Transcriptional regulator
ABE28_RS10430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABE28_RS10435	COG0022	dehydrogenase e1 component
ABE28_RS10445	COG0346	lactoylglutathione lyase activity
ABE28_RS10480	COG0384	phenazine biosynthesis protein PhzF
ABE28_RS10485	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
ABE28_RS10490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABE28_RS10500	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ABE28_RS10510	COG2271	Major facilitator Superfamily
ABE28_RS10515	COG0277	FAD linked oxidase domain protein
ABE28_RS10525	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABE28_RS10530	COG1228	amidohydrolase
ABE28_RS10535	COG2271	Major facilitator Superfamily
ABE28_RS10540	COG0477	Major facilitator Superfamily
ABE28_RS10545	COG2986	histidine ammonia-lyase
ABE28_RS10555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABE28_RS10560	COG1914	H( )-stimulated, divalent metal cation uptake system
ABE28_RS10565	COG4336	lyase activity
ABE28_RS10570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABE28_RS10575	COG1984	allophanate hydrolase subunit 2
ABE28_RS10580	COG1414	Transcriptional regulator
ABE28_RS10595	COG0583	DNA-binding transcription factor activity
ABE28_RS10600	COG0010	Belongs to the arginase family
ABE28_RS10605	COG2135	peptidase activity
ABE28_RS10615	COG1115	amino acid carrier protein
ABE28_RS10625	COG1492	cobalamin metabolic process
ABE28_RS10635	COG0515	serine threonine protein kinase
ABE28_RS10640	COG3397	chitin binding
ABE28_RS10645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABE28_RS10650	COG4721	ABC-type cobalt transport system, permease component
ABE28_RS10655	COG4172	Belongs to the ABC transporter superfamily
ABE28_RS10665	COG0352	thiamine-phosphate diphosphorylase activity
ABE28_RS10670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABE28_RS10680	COG2022	thiamine diphosphate biosynthetic process
ABE28_RS10685	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABE28_RS10705	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABE28_RS10710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABE28_RS10725	COG0824	Thioesterase
ABE28_RS10735	COG4841	protein insertion into membrane
ABE28_RS10745	COG3093	addiction module antidote protein HigA
ABE28_RS10755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ABE28_RS10760	COG1832	CoA-binding protein
ABE28_RS10765	COG0187	DNA topoisomerase II activity
ABE28_RS10770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABE28_RS10775	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS10780	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS10785	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS10795	COG2030	dehydratase
ABE28_RS10810	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ABE28_RS10815	COG1737	Transcriptional regulator
ABE28_RS10820	COG1263	PTS System
ABE28_RS10820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS10830	COG1472	Belongs to the glycosyl hydrolase 3 family
ABE28_RS10835	COG3876	Protein conserved in bacteria
ABE28_RS10840	COG1263	PTS System
ABE28_RS10840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS10850	COG0673	inositol 2-dehydrogenase activity
ABE28_RS10855	COG2814	Major facilitator Superfamily
ABE28_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS10875	COG3964	amidohydrolase
ABE28_RS10895	COG2188	Transcriptional regulator
ABE28_RS10905	COG0583	DNA-binding transcription factor activity
ABE28_RS10910	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABE28_RS10915	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABE28_RS10935	COG0697	spore germination
ABE28_RS10940	COG0814	amino acid
ABE28_RS10950	COG1231	oxidoreductase activity
ABE28_RS10955	COG1271	oxidase subunit
ABE28_RS10960	COG1294	oxidase, subunit
ABE28_RS10970	COG1309	transcriptional regulator
ABE28_RS10975	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS10980	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS10985	COG0439	Biotin carboxylase
ABE28_RS10990	COG0511	ligase activity, forming carbon-carbon bonds
ABE28_RS10995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABE28_RS11000	COG1024	Enoyl-CoA hydratase
ABE28_RS11005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABE28_RS11015	COG1335	isochorismatase
ABE28_RS11020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ABE28_RS11025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABE28_RS11065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS11065	COG1263	PTS System
ABE28_RS11075	COG1525	nuclease
ABE28_RS11090	COG1876	peptidase activity
ABE28_RS11100	COG2814	Major facilitator Superfamily
ABE28_RS11105	COG2213	PTS system mannitol-specific
ABE28_RS11110	COG3711	transcriptional antiterminator
ABE28_RS11115	COG1070	Carbohydrate kinase
ABE28_RS11120	COG1063	alcohol dehydrogenase
ABE28_RS11145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS11150	COG0454	-acetyltransferase
ABE28_RS11160	COG0745	RESPONSE REGULATOR receiver
ABE28_RS11165	COG4607	ABC-type enterochelin transport system periplasmic component
ABE28_RS11220	COG0840	transmembrane signaling receptor activity
ABE28_RS11225	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABE28_RS11235	COG2814	Major facilitator Superfamily
ABE28_RS11245	COG1742	UPF0060 membrane protein
ABE28_RS11250	COG0697	spore germination
ABE28_RS11280	COG0401	homolog of Blt101
ABE28_RS11310	COG2244	polysaccharide biosynthetic process
ABE28_RS11320	COG0833	amino acid
ABE28_RS11355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABE28_RS11365	COG5609	conserved protein (DUF2294)
ABE28_RS11370	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABE28_RS11375	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABE28_RS11385	COG2205	protein histidine kinase activity
ABE28_RS11400	COG2226	methyltransferase
ABE28_RS11415	COG0741	lytic transglycosylase activity
ABE28_RS11460	COG0024	Methionine aminopeptidase
ABE28_RS11475	COG1160	GTP binding
ABE28_RS11480	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS11490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABE28_RS11515	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABE28_RS11520	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS11525	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS11535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ABE28_RS11545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABE28_RS11550	COG2721	sulfolactate sulfo-lyase activity
ABE28_RS11555	COG2721	sulfolactate sulfo-lyase activity
ABE28_RS11565	COG0753	catalase activity
ABE28_RS11570	COG1486	melibiose metabolic process
ABE28_RS11575	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABE28_RS11590	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS11600	COG2723	6-phospho-beta-galactosidase activity
ABE28_RS11620	COG1621	beta-fructofuranosidase activity
ABE28_RS11625	COG1609	Transcriptional regulator
ABE28_RS11640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABE28_RS11645	COG1621	beta-fructofuranosidase activity
ABE28_RS11655	COG1609	Transcriptional regulator
ABE28_RS11665	COG0247	lactate metabolic process
ABE28_RS11670	COG0277	FAD linked oxidase domain protein
ABE28_RS11680	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABE28_RS11685	COG3842	ATPase activity
ABE28_RS11690	COG1840	ABC-type Fe3 transport system, periplasmic component
ABE28_RS11705	COG3852	Histidine kinase
ABE28_RS11725	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ABE28_RS11740	COG2814	Major facilitator Superfamily
ABE28_RS11745	COG0668	transmembrane transport
ABE28_RS11780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABE28_RS11805	COG0579	oxidoreductase
ABE28_RS11820	COG0582	viral genome integration into host DNA
ABE28_RS11825	COG0346	lactoylglutathione lyase activity
ABE28_RS11830	COG1473	amidohydrolase
ABE28_RS11835	COG0252	asparaginase activity
ABE28_RS11840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABE28_RS11855	COG4294	response to UV
ABE28_RS11865	COG1523	belongs to the glycosyl hydrolase 13 family
ABE28_RS11870	COG0542	response to heat
ABE28_RS11885	COG1388	LysM domain
ABE28_RS11885	COG0791	NLP P60 protein
ABE28_RS11905	COG0583	DNA-binding transcription factor activity
ABE28_RS11915	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABE28_RS11920	COG1174	glycine betaine transport
ABE28_RS11925	COG1732	Glycine betaine
ABE28_RS11930	COG1174	glycine betaine transport
ABE28_RS11935	COG1125	glycine betaine transport
ABE28_RS11935	COG0517	IMP dehydrogenase activity
ABE28_RS11945	COG2271	Major facilitator Superfamily
ABE28_RS11965	COG0702	epimerase
ABE28_RS11970	COG0406	alpha-ribazole phosphatase activity
ABE28_RS11985	COG1403	HNH endonuclease
ABE28_RS11995	COG0708	Exodeoxyribonuclease III
ABE28_RS12000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABE28_RS12005	COG0297	glycogen (starch) synthase activity
ABE28_RS12010	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ABE28_RS12015	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ABE28_RS12020	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ABE28_RS12030	COG3663	DNA glycosylase
ABE28_RS12050	COG0730	response to heat
ABE28_RS12075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABE28_RS12080	COG0529	Catalyzes the synthesis of activated sulfate
ABE28_RS12090	COG0175	sulfate reduction
ABE28_RS12100	COG0431	NADPH-dependent FMN reductase
ABE28_RS12105	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABE28_RS12110	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ABE28_RS12115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABE28_RS12130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS12135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABE28_RS12145	COG1164	Oligoendopeptidase f
ABE28_RS12155	COG3403	YqcI/YcgG family
ABE28_RS12175	COG2197	response regulator
ABE28_RS12185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABE28_RS12190	COG0628	permease
ABE28_RS12200	COG1376	ErfK ybiS ycfS ynhG family protein
ABE28_RS12220	COG0765	amino acid transport
ABE28_RS12225	COG0765	amino acid transport
ABE28_RS12230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS12235	COG1126	abc transporter atp-binding protein
ABE28_RS12245	COG0679	Auxin Efflux Carrier
ABE28_RS12250	COG0590	tRNA wobble adenosine to inosine editing
ABE28_RS12260	COG2706	6-phosphogluconolactonase activity
ABE28_RS12275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABE28_RS12280	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS12295	COG1278	Cold shock
ABE28_RS12300	COG1024	Enoyl-CoA hydratase
ABE28_RS12310	COG4608	Belongs to the ABC transporter superfamily
ABE28_RS12315	COG0444	Belongs to the ABC transporter superfamily
ABE28_RS12320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS12325	COG0601	transmembrane transport
ABE28_RS12330	COG4166	transmembrane transport
ABE28_RS12405	COG2340	Cysteine-rich secretory protein family
ABE28_RS12415	COG2176	DNA-directed DNA polymerase activity
ABE28_RS12420	COG1511	domain protein
ABE28_RS12430	COG0561	phosphatase activity
ABE28_RS12435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ABE28_RS12445	COG1113	amino acid transport
ABE28_RS12450	COG3852	Histidine kinase
ABE28_RS12455	COG3541	Predicted nucleotidyltransferase
ABE28_RS12460	COG0861	Integral membrane protein TerC family
ABE28_RS12465	COG0246	Mannitol dehydrogenase
ABE28_RS12470	COG1063	alcohol dehydrogenase
ABE28_RS12475	COG2721	sulfolactate sulfo-lyase activity
ABE28_RS12480	COG2207	Transcriptional regulator
ABE28_RS12480	COG3708	Transcriptional regulator
ABE28_RS12485	COG2271	Major facilitator Superfamily
ABE28_RS12490	COG1609	Transcriptional regulator
ABE28_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS12500	COG1312	Catalyzes the dehydration of D-mannonate
ABE28_RS12505	COG0800	Aldolase
ABE28_RS12510	COG1063	alcohol dehydrogenase
ABE28_RS12515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABE28_RS12530	COG2046	Belongs to the sulfate adenylyltransferase family
ABE28_RS12535	COG0529	Catalyzes the synthesis of activated sulfate
ABE28_RS12540	COG0730	response to heat
ABE28_RS12545	COG0463	Glycosyl transferase, family 2
ABE28_RS12545	COG1216	Glycosyl transferase, family 2
ABE28_RS12550	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS12560	COG1216	Glycosyl transferase, family 2
ABE28_RS12580	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS12595	COG1086	Polysaccharide biosynthesis protein
ABE28_RS12605	COG2910	NAD(P)H-binding
ABE28_RS12610	COG1132	(ABC) transporter
ABE28_RS12620	COG3858	chitin binding
ABE28_RS12620	COG1388	LysM domain
ABE28_RS12625	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS12630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABE28_RS12635	COG1937	Protein conserved in bacteria
ABE28_RS12650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABE28_RS12655	COG0400	carboxylic ester hydrolase activity
ABE28_RS12660	COG0346	lactoylglutathione lyase activity
ABE28_RS12665	COG0346	lactoylglutathione lyase activity
ABE28_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS12690	COG1764	response to oxidative stress
ABE28_RS12715	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ABE28_RS12720	COG1733	regulation of RNA biosynthetic process
ABE28_RS12725	COG0492	ferredoxin-NADP+ reductase activity
ABE28_RS12740	COG0823	Involved in the tonB-independent uptake of proteins
ABE28_RS12740	COG4946	Tricorn protease homolog
ABE28_RS12740	COG1506	peptidase
ABE28_RS12745	COG0768	penicillin binding
ABE28_RS12755	COG0768	penicillin binding
ABE28_RS12770	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ABE28_RS12775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS12780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ABE28_RS12785	COG1131	(ABC) transporter
ABE28_RS12795	COG2814	Major facilitator Superfamily
ABE28_RS12800	COG5002	protein histidine kinase activity
ABE28_RS12805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS12820	COG0514	ATP-dependent DNA helicase (RecQ)
ABE28_RS12825	COG3584	3D domain protein
ABE28_RS12825	COG1388	LysM domain
ABE28_RS12840	COG3546	catalase activity
ABE28_RS12845	COG2996	Protein conserved in bacteria
ABE28_RS12850	COG5002	protein histidine kinase activity
ABE28_RS12855	COG0745	RESPONSE REGULATOR receiver
ABE28_RS12865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABE28_RS12885	COG3973	AAA domain
ABE28_RS12895	COG0488	(ABC) transporter
ABE28_RS12905	COG2268	Band 7 protein
ABE28_RS12910	COG1585	Membrane protein implicated in regulation of membrane protease activity
ABE28_RS12915	COG1268	BioY protein
ABE28_RS12925	COG1272	protein, Hemolysin III
ABE28_RS12930	COG0640	Transcriptional regulator
ABE28_RS12935	COG3773	Cell wall hydrolase
ABE28_RS12945	COG0432	Pfam Uncharacterised protein family UPF0047
ABE28_RS12955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABE28_RS12955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABE28_RS12955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABE28_RS12960	COG1105	Belongs to the carbohydrate kinase PfkB family
ABE28_RS12965	COG1349	DNA-binding transcription factor activity
ABE28_RS12970	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABE28_RS12975	COG0567	Dehydrogenase, E1 component
ABE28_RS12980	COG3384	dioxygenase
ABE28_RS12990	COG1410	methionine synthase
ABE28_RS12990	COG0646	methionine synthase
ABE28_RS12995	COG0646	methionine synthase
ABE28_RS12995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABE28_RS13000	COG2258	MOSC domain
ABE28_RS13005	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ABE28_RS13010	COG1793	dna ligase
ABE28_RS13010	COG3285	dna ligase
ABE28_RS13015	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ABE28_RS13025	COG0288	reversible hydration of carbon dioxide
ABE28_RS13055	COG1380	Effector of murein hydrolase LrgA
ABE28_RS13060	COG1346	cytolysis
ABE28_RS13070	COG0668	transmembrane transport
ABE28_RS13075	COG0534	Mate efflux family protein
ABE28_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS13090	COG2340	Cysteine-rich secretory protein family
ABE28_RS13100	COG5002	protein histidine kinase activity
ABE28_RS13105	COG0745	RESPONSE REGULATOR receiver
ABE28_RS13125	COG0523	cobalamin synthesis protein
ABE28_RS13130	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ABE28_RS13135	COG0235	Class ii aldolase
ABE28_RS13140	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ABE28_RS13145	COG1850	ribulose-bisphosphate carboxylase activity
ABE28_RS13150	COG0436	Aminotransferase
ABE28_RS13155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABE28_RS13160	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ABE28_RS13165	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ABE28_RS13175	COG0793	Belongs to the peptidase S41A family
ABE28_RS13175	COG3409	Peptidoglycan-binding domain 1 protein
ABE28_RS13230	COG2801	Transposase and inactivated derivatives
ABE28_RS13240	COG5002	protein histidine kinase activity
ABE28_RS13245	COG4479	Belongs to the UPF0346 family
ABE28_RS13255	COG1509	lysine 2,3-aminomutase activity
ABE28_RS13260	COG3829	transcription factor binding
ABE28_RS13265	COG0456	acetyltransferase
ABE28_RS13270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABE28_RS13275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABE28_RS13280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABE28_RS13285	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABE28_RS13295	COG1619	proteins homologs of microcin C7 resistance protein MccF
ABE28_RS13310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABE28_RS13315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABE28_RS13325	COG4698	Protein conserved in bacteria
ABE28_RS13335	COG1999	signal sequence binding
ABE28_RS13340	COG1307	EDD domain protein, DegV family
ABE28_RS13350	COG0805	protein transport
ABE28_RS13355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ABE28_RS13360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABE28_RS13365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ABE28_RS13385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ABE28_RS13390	COG0861	Integral membrane protein TerC family
ABE28_RS13400	COG0405	Gamma-glutamyltransferase
ABE28_RS13405	COG2136	Putative SAM-dependent methyltransferase
ABE28_RS13405	COG2521	methyltransferase
ABE28_RS13415	COG1388	LysM domain
ABE28_RS13425	COG0129	dihydroxy-acid dehydratase activity
ABE28_RS13430	COG1413	lyase activity
ABE28_RS13435	COG0488	(ABC) transporter
ABE28_RS13440	COG1418	mRNA catabolic process
ABE28_RS13445	COG1307	EDD domain protein, DegV family
ABE28_RS13450	COG0386	Belongs to the glutathione peroxidase family
ABE28_RS13460	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ABE28_RS13480	COG1321	iron dependent repressor
ABE28_RS13485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABE28_RS13495	COG2213	PTS system mannitol-specific
ABE28_RS13500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABE28_RS13505	COG0246	Mannitol dehydrogenase
ABE28_RS13510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ABE28_RS13515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABE28_RS13520	COG1349	DNA-binding transcription factor activity
ABE28_RS13530	COG2318	DinB family
ABE28_RS13555	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS13565	COG0395	ABC-type sugar transport system, permease component
ABE28_RS13570	COG1175	transmembrane transport
ABE28_RS13580	COG1609	Transcriptional regulator
ABE28_RS13585	COG3684	Belongs to the aldolase LacD family
ABE28_RS13595	COG2222	sugar isomerase
ABE28_RS13600	COG1940	carbohydrate kinase activity
ABE28_RS13605	COG0395	ABC-type sugar transport system, permease component
ABE28_RS13610	COG1175	transmembrane transport
ABE28_RS13625	COG1609	Transcriptional regulator
ABE28_RS13630	COG2188	Transcriptional regulator
ABE28_RS13640	COG1940	carbohydrate kinase activity
ABE28_RS13650	COG0778	Nitroreductase
ABE28_RS13655	COG2188	Transcriptional regulator
ABE28_RS13660	COG1737	Transcriptional regulator
ABE28_RS13665	COG2971	BadF BadG BcrA BcrD
ABE28_RS13675	COG1447	Phosphotransferase system cellobiose-specific component IIA
ABE28_RS13680	COG1486	melibiose metabolic process
ABE28_RS13690	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ABE28_RS13705	COG1649	PFAM Uncharacterised BCR, COG1649
ABE28_RS13715	COG0833	amino acid
ABE28_RS13725	COG1288	antiporter activity
ABE28_RS13730	COG4187	Peptidase family M20/M25/M40
ABE28_RS13755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABE28_RS13760	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ABE28_RS13765	COG3716	PTS system mannose fructose sorbose family IID component
ABE28_RS13770	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS13780	COG1737	Transcriptional regulator
ABE28_RS13785	COG0531	amino acid
ABE28_RS13795	COG0666	response to abiotic stimulus
ABE28_RS13800	COG0745	RESPONSE REGULATOR receiver
ABE28_RS13805	COG5002	protein histidine kinase activity
ABE28_RS13810	COG1233	COG1233 Phytoene dehydrogenase and related
ABE28_RS13815	COG1562	ergosterol biosynthetic process
ABE28_RS13820	COG1233	COG1233 Phytoene dehydrogenase and related
ABE28_RS13850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ABE28_RS13855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABE28_RS13870	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS13875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABE28_RS13885	COG0328	RNA-DNA hybrid ribonuclease activity
ABE28_RS13890	COG0328	RNA-DNA hybrid ribonuclease activity
ABE28_RS13905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABE28_RS13920	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABE28_RS13925	COG1755	Isoprenylcysteine carboxyl methyltransferase
ABE28_RS13930	COG3424	synthase
ABE28_RS13940	COG2233	PERMEase
ABE28_RS13945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABE28_RS13950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ABE28_RS13955	COG1199	ATP-dependent helicase activity
ABE28_RS13965	COG1278	Cold shock
ABE28_RS13970	COG0116	Belongs to the methyltransferase superfamily
ABE28_RS13985	COG3599	regulation of cell shape
ABE28_RS14000	COG3359	exonuclease
ABE28_RS14005	COG1205	dead DEAH box helicase
ABE28_RS14005	COG1111	helicase
ABE28_RS14010	COG2267	carboxylic ester hydrolase activity
ABE28_RS14040	COG3331	DNA recombination
ABE28_RS14045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABE28_RS14045	COG4499	WXG100 protein secretion system (Wss), protein YukC
ABE28_RS14055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABE28_RS14060	COG3935	DnaD domain protein
ABE28_RS14065	COG0017	Asparaginyl-tRNA synthetase
ABE28_RS14095	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS14100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABE28_RS14110	COG0436	Aminotransferase
ABE28_RS14115	COG5353	protein conserved in bacteria
ABE28_RS14125	COG1199	ATP-dependent helicase activity
ABE28_RS14125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABE28_RS14130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ABE28_RS14135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ABE28_RS14140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ABE28_RS14150	COG0617	tRNA 3'-terminal CCA addition
ABE28_RS14155	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS14160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABE28_RS14165	COG1803	Methylglyoxal synthase
ABE28_RS14175	COG1694	Mazg nucleotide pyrophosphohydrolase
ABE28_RS14180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS14185	COG2738	Putative neutral zinc metallopeptidase
ABE28_RS14195	COG4347	Protein of unknown function (DUF1405)
ABE28_RS14200	COG2010	Cytochrome c
ABE28_RS14200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ABE28_RS14220	COG5582	Belongs to the UPF0302 family
ABE28_RS14225	COG0457	Tetratricopeptide repeat
ABE28_RS14230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABE28_RS14235	COG0287	Prephenate dehydrogenase
ABE28_RS14240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABE28_RS14245	COG4401	Chorismate mutase type I
ABE28_RS14250	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ABE28_RS14255	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ABE28_RS14260	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ABE28_RS14265	COG0105	UTP biosynthetic process
ABE28_RS14270	COG0142	geranyltranstransferase activity
ABE28_RS14275	COG2226	methyltransferase
ABE28_RS14280	COG0142	geranyltranstransferase activity
ABE28_RS14290	COG0302	gtp cyclohydrolase
ABE28_RS14295	COG0776	regulation of translation
ABE28_RS14300	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ABE28_RS14320	COG3290	protein histidine kinase activity
ABE28_RS14320	COG3829	transcription factor binding
ABE28_RS14325	COG0531	amino acid
ABE28_RS14350	COG1304	FMN binding
ABE28_RS14355	COG0539	negative regulation of cytoplasmic translation
ABE28_RS14365	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABE28_RS14380	COG2959	enzyme of heme biosynthesis
ABE28_RS14385	COG3409	Peptidoglycan-binding domain 1 protein
ABE28_RS14385	COG3773	Cell wall hydrolase
ABE28_RS14390	COG2339	peptidase activity
ABE28_RS14400	COG0492	ferredoxin-NADP+ reductase activity
ABE28_RS14405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABE28_RS14410	COG4862	establishment of competence for transformation
ABE28_RS14420	COG1408	metallophosphoesterase
ABE28_RS14430	COG1388	LysM domain
ABE28_RS14435	COG1266	CAAX protease self-immunity
ABE28_RS14440	COG0514	ATP-dependent DNA helicase (RecQ)
ABE28_RS14445	COG4955	Helix-turn-helix domain
ABE28_RS14455	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ABE28_RS14460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABE28_RS14470	COG1595	DNA-templated transcription, initiation
ABE28_RS14475	COG5002	protein histidine kinase activity
ABE28_RS14480	COG0745	RESPONSE REGULATOR receiver
ABE28_RS14485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABE28_RS14490	COG1333	cytochrome c biogenesis protein
ABE28_RS14495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABE28_RS14500	COG1187	pseudouridine synthase activity
ABE28_RS14505	COG0700	Nucleoside recognition
ABE28_RS14510	COG2715	membrane protein required for spore maturation
ABE28_RS14515	COG1686	Belongs to the peptidase S11 family
ABE28_RS14525	COG0450	alkyl hydroperoxide reductase
ABE28_RS14530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABE28_RS14545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABE28_RS14555	COG1547	Domain of unknown function (DUF309)
ABE28_RS14565	COG4086	secreted protein
ABE28_RS14575	COG0697	spore germination
ABE28_RS14595	COG2252	PERMEase
ABE28_RS14605	COG2172	sigma factor antagonist activity
ABE28_RS14615	COG1686	Belongs to the peptidase S11 family
ABE28_RS14635	COG4974	Belongs to the 'phage' integrase family
ABE28_RS14645	COG0735	belongs to the Fur family
ABE28_RS14650	COG1300	Membrane
ABE28_RS14660	COG1379	DNA repair
ABE28_RS14670	COG0667	Aldo Keto reductase
ABE28_RS14675	COG1764	response to oxidative stress
ABE28_RS14680	COG1846	Transcriptional regulator
ABE28_RS14690	COG1073	alpha beta
ABE28_RS14695	COG4918	Iron-sulphur cluster biosynthesis
ABE28_RS14705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABE28_RS14710	COG1388	LysM domain
ABE28_RS14710	COG0791	NLP P60 protein
ABE28_RS14725	COG0300	oxidoreductase activity
ABE28_RS14730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS14735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABE28_RS14745	COG0789	Transcriptional regulator
ABE28_RS14750	COG1122	ATPase activity
ABE28_RS14770	COG1234	tRNA 3'-trailer cleavage
ABE28_RS14775	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ABE28_RS14785	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ABE28_RS14790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABE28_RS14795	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABE28_RS14800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABE28_RS14810	COG1376	ErfK ybiS ycfS ynhG family protein
ABE28_RS14815	COG4129	membrane
ABE28_RS14820	COG1126	abc transporter atp-binding protein
ABE28_RS14825	COG0765	amino acid transport
ABE28_RS14830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS14840	COG1703	isobutyryl-CoA mutase activity
ABE28_RS14845	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABE28_RS14845	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABE28_RS14855	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABE28_RS14860	COG0022	dehydrogenase e1 component
ABE28_RS14865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABE28_RS14870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABE28_RS14880	COG3290	protein histidine kinase activity
ABE28_RS14880	COG3829	transcription factor binding
ABE28_RS14890	COG0584	glycerophosphoryl diester phosphodiesterase
ABE28_RS14900	COG0745	RESPONSE REGULATOR receiver
ABE28_RS14905	COG0750	zinc metalloprotease
ABE28_RS14910	COG0497	DNA recombination
ABE28_RS14915	COG1438	arginine binding
ABE28_RS14920	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ABE28_RS14925	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ABE28_RS14935	COG1722	exodeoxyribonuclease VII activity
ABE28_RS14950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ABE28_RS14955	COG1302	Protein conserved in bacteria
ABE28_RS14960	COG0439	Biotin carboxylase
ABE28_RS14965	COG0511	ligase activity, forming carbon-carbon bonds
ABE28_RS15005	COG3854	ATPases associated with a variety of cellular activities
ABE28_RS15010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABE28_RS15015	COG0006	proline dipeptidase activity
ABE28_RS15030	COG3872	metal-dependent enzyme
ABE28_RS15040	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABE28_RS15055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABE28_RS15060	COG0095	Lipoate-protein ligase
ABE28_RS15065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABE28_RS15070	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABE28_RS15075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABE28_RS15085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABE28_RS15120	COG4537	Required for transformation and DNA binding
ABE28_RS15125	COG1459	type II secretion system
ABE28_RS15130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABE28_RS15135	COG1393	Belongs to the ArsC family
ABE28_RS15155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS15170	COG1404	Belongs to the peptidase S8 family
ABE28_RS15185	COG1940	carbohydrate kinase activity
ABE28_RS15200	COG0705	Rhomboid family
ABE28_RS15200	COG0457	Tetratricopeptide repeat
ABE28_RS15210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABE28_RS15230	COG0704	Plays a role in the regulation of phosphate uptake
ABE28_RS15240	COG0581	inorganic phosphate transmembrane transporter activity
ABE28_RS15245	COG0573	inorganic phosphate transmembrane transporter activity
ABE28_RS15250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABE28_RS15255	COG0768	penicillin binding
ABE28_RS15260	COG0477	Major facilitator Superfamily
ABE28_RS15270	COG2839	Protein conserved in bacteria
ABE28_RS15275	COG5521	maltodextrose utilization protein MalA
ABE28_RS15285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ABE28_RS15290	COG4709	membrane
ABE28_RS15295	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
ABE28_RS15300	COG0735	belongs to the Fur family
ABE28_RS15305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABE28_RS15310	COG1121	(ABC) transporter
ABE28_RS15320	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ABE28_RS15325	COG0513	Belongs to the DEAD box helicase family
ABE28_RS15345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABE28_RS15350	COG2384	SAM-dependent methyltransferase
ABE28_RS15355	COG2010	Cytochrome c
ABE28_RS15365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ABE28_RS15370	COG0358	DNA primase activity
ABE28_RS15375	COG1671	Belongs to the UPF0178 family
ABE28_RS15380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ABE28_RS15385	COG0517	IMP dehydrogenase activity
ABE28_RS15390	COG0751	glycine-tRNA ligase activity
ABE28_RS15395	COG0752	glycyl-tRNA synthetase alpha subunit
ABE28_RS15400	COG1381	Involved in DNA repair and RecF pathway recombination
ABE28_RS15410	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABE28_RS15415	COG0295	cytidine deaminase activity
ABE28_RS15420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABE28_RS15430	COG1480	7TM receptor with intracellular HD hydrolase
ABE28_RS15435	COG1702	phosphate starvation-inducible protein PhoH
ABE28_RS15455	COG4864	UPF0365 protein
ABE28_RS15460	COG1030	water channel activity
ABE28_RS15465	COG1610	YqeY-like protein
ABE28_RS15470	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ABE28_RS15475	COG1283	sodium-dependent phosphate transmembrane transporter activity
ABE28_RS15485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ABE28_RS15490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABE28_RS15495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABE28_RS15500	COG2264	protein methyltransferase activity
ABE28_RS15505	COG0484	heat shock protein binding
ABE28_RS15510	COG0443	Heat shock 70 kDa protein
ABE28_RS15520	COG1420	regulation of RNA biosynthetic process
ABE28_RS15525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABE28_RS15540	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABE28_RS15550	COG0268	Binds directly to 16S ribosomal RNA
ABE28_RS15555	COG1466	dna polymerase III delta subunit
ABE28_RS15565	COG2333	competence protein COMEC
ABE28_RS15565	COG0658	competence protein
ABE28_RS15570	COG2131	deaminase
ABE28_RS15575	COG1596	polysaccharide export
ABE28_RS15575	COG1555	photosystem II stabilization
ABE28_RS15580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ABE28_RS15585	COG2226	methyltransferase
ABE28_RS15590	COG0799	negative regulation of ribosome biogenesis
ABE28_RS15595	COG1713	HD superfamily hydrolase involved in NAD metabolism
ABE28_RS15600	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ABE28_RS15605	COG1534	Rna-binding protein
ABE28_RS15615	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ABE28_RS15620	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ABE28_RS15630	COG0688	phosphatidylethanolamine metabolic process
ABE28_RS15635	COG1183	phosphatidylcholine synthase activity
ABE28_RS15665	COG0626	cystathionine gamma-synthase activity
ABE28_RS15670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABE28_RS15680	COG2226	methyltransferase
ABE28_RS15695	COG0768	penicillin binding
ABE28_RS15700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABE28_RS15705	COG0572	uridine kinase
ABE28_RS15710	COG0826	peptidase U32
ABE28_RS15715	COG0826	peptidase U32
ABE28_RS15720	COG4122	O-methyltransferase activity
ABE28_RS15725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABE28_RS15730	COG3906	Belongs to the UPF0473 family
ABE28_RS15735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABE28_RS15750	COG0628	permease
ABE28_RS15760	COG3881	PFAM PRC-barrel domain
ABE28_RS15770	COG1704	LemA family
ABE28_RS15775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABE28_RS15785	COG0482	sulfurtransferase activity
ABE28_RS15790	COG1104	cysteine desulfurase activity
ABE28_RS15795	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS15810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABE28_RS15825	COG1131	(ABC) transporter
ABE28_RS15830	COG1725	Transcriptional regulator
ABE28_RS15840	COG1316	TRANSCRIPTIONal
ABE28_RS15855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABE28_RS15860	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS15875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABE28_RS15880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABE28_RS15900	COG0489	protein tyrosine kinase activity
ABE28_RS15905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABE28_RS15910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABE28_RS15925	COG1215	transferase activity, transferring glycosyl groups
ABE28_RS16000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABE28_RS16010	COG1086	Polysaccharide biosynthesis protein
ABE28_RS16020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABE28_RS16030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABE28_RS16035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ABE28_RS16045	COG4464	protein tyrosine phosphatase activity
ABE28_RS16050	COG0489	protein tyrosine kinase activity
ABE28_RS16055	COG3944	biosynthesis protein
ABE28_RS16095	COG0411	ABC transporter
ABE28_RS16120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABE28_RS16140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ABE28_RS16145	COG0124	histidyl-tRNA synthetase
ABE28_RS16150	COG3103	Sh3 type 3 domain protein
ABE28_RS16150	COG4991	sh3 domain protein
ABE28_RS16150	COG0860	N-Acetylmuramoyl-L-alanine amidase
ABE28_RS16155	COG1490	D-aminoacyl-tRNA deacylase activity
ABE28_RS16160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABE28_RS16165	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABE28_RS16170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ABE28_RS16170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABE28_RS16175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABE28_RS16175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ABE28_RS16185	COG2244	polysaccharide biosynthetic process
ABE28_RS16190	COG2323	membrane
ABE28_RS16200	COG1862	Preprotein translocase
ABE28_RS16210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABE28_RS16225	COG0632	four-way junction helicase activity
ABE28_RS16265	COG2321	neutral zinc metallopeptidase
ABE28_RS16275	COG0157	Belongs to the NadC ModD family
ABE28_RS16280	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ABE28_RS16285	COG1104	cysteine desulfurase activity
ABE28_RS16290	COG1827	regulation of RNA biosynthetic process
ABE28_RS16305	COG2801	Transposase and inactivated derivatives
ABE28_RS16310	COG0077	Prephenate dehydratase
ABE28_RS16315	COG4492	Belongs to the UPF0735 family
ABE28_RS16320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABE28_RS16325	COG3290	protein histidine kinase activity
ABE28_RS16335	COG2868	ribosomal protein
ABE28_RS16340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ABE28_RS16345	COG1530	ribonuclease E activity
ABE28_RS16350	COG1994	Peptidase M50
ABE28_RS16355	COG0739	heme binding
ABE28_RS16360	COG1098	S1 RNA binding domain
ABE28_RS16365	COG2894	cell division
ABE28_RS16370	COG0850	regulation of cytokinetic process
ABE28_RS16380	COG1792	Involved in formation and maintenance of cell shape
ABE28_RS16385	COG1077	Cell shape determining protein MreB Mrl
ABE28_RS16390	COG2003	Belongs to the UPF0758 family
ABE28_RS16405	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ABE28_RS16410	COG0285	dihydrofolate synthase activity
ABE28_RS16415	COG0189	ligase activity
ABE28_RS16420	COG0189	ligase activity
ABE28_RS16425	COG0525	valine-tRNA ligase activity
ABE28_RS16435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABE28_RS16440	COG1388	LysM domain
ABE28_RS16445	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ABE28_RS16450	COG0113	porphobilinogen synthase activity
ABE28_RS16460	COG0181	hydroxymethylbilane synthase activity
ABE28_RS16465	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ABE28_RS16480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ABE28_RS16485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABE28_RS16490	COG0470	DNA polymerase III
ABE28_RS16490	COG1067	ATP-dependent peptidase activity
ABE28_RS16505	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABE28_RS16515	COG0066	3-isopropylmalate dehydratase activity
ABE28_RS16520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABE28_RS16525	COG0473	3-isopropylmalate dehydrogenase activity
ABE28_RS16530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABE28_RS16535	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ABE28_RS16540	COG0440	acetolactate synthase activity
ABE28_RS16545	COG0028	Belongs to the TPP enzyme family
ABE28_RS16605	COG1131	(ABC) transporter
ABE28_RS16625	COG0622	Phosphoesterase
ABE28_RS16630	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABE28_RS16635	COG5401	PFAM Sporulation and spore germination
ABE28_RS16645	COG1846	Transcriptional regulator
ABE28_RS16650	COG2197	response regulator
ABE28_RS16655	COG0824	Thioesterase
ABE28_RS16660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABE28_RS16665	COG1053	succinate dehydrogenase
ABE28_RS16670	COG2009	succinate dehydrogenase
ABE28_RS16675	COG1719	4-vinyl reductase, 4VR
ABE28_RS16690	COG3118	belongs to the thioredoxin family
ABE28_RS16695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ABE28_RS16700	COG2086	electron transfer activity
ABE28_RS16705	COG1024	Enoyl-CoA hydratase
ABE28_RS16710	COG1309	transcriptional regulator
ABE28_RS16715	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS16720	COG3766	membrane
ABE28_RS16725	COG1193	negative regulation of DNA recombination
ABE28_RS16730	COG1796	DNA polymerase
ABE28_RS16730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABE28_RS16735	COG1286	toxin biosynthetic process
ABE28_RS16740	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ABE28_RS16745	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABE28_RS16750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABE28_RS16750	COG0072	phenylalanine-tRNA ligase activity
ABE28_RS16755	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ABE28_RS16760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABE28_RS16785	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ABE28_RS16790	COG0247	lactate metabolic process
ABE28_RS16795	COG0277	FAD linked oxidase domain protein
ABE28_RS16800	COG3835	regulator
ABE28_RS16805	COG1620	l-lactate permease
ABE28_RS16810	COG2186	Transcriptional regulator
ABE28_RS16815	COG0247	lactate metabolic process
ABE28_RS16820	COG1139	Iron-sulfur cluster binding protein
ABE28_RS16825	COG1556	Lactate utilization protein
ABE28_RS16830	COG1363	Peptidase, m42
ABE28_RS16850	COG3326	Membrane
ABE28_RS16855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ABE28_RS16865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ABE28_RS16870	COG1247	-acetyltransferase
ABE28_RS16875	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABE28_RS16885	COG1484	DNA-dependent DNA replication
ABE28_RS16890	COG3611	Membrane attachment protein
ABE28_RS16895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ABE28_RS16900	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABE28_RS16905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABE28_RS16910	COG0237	dephospho-CoA kinase activity
ABE28_RS16915	COG1971	Probably functions as a manganese efflux pump
ABE28_RS16920	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ABE28_RS16925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABE28_RS16925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABE28_RS16930	COG0330	HflC and HflK could
ABE28_RS16935	COG0330	HflC and HflK could
ABE28_RS16940	COG5002	protein histidine kinase activity
ABE28_RS16945	COG0745	RESPONSE REGULATOR receiver
ABE28_RS16950	COG0039	L-malate dehydrogenase activity
ABE28_RS16955	COG0538	isocitrate dehydrogenase activity
ABE28_RS16960	COG0372	Belongs to the citrate synthase family
ABE28_RS16970	COG0628	permease
ABE28_RS16975	COG2224	Isocitrate lyase
ABE28_RS16980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABE28_RS16995	COG0205	6-phosphofructokinase activity
ABE28_RS17000	COG0825	malonyl-CoA metabolic process
ABE28_RS17005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ABE28_RS17010	COG2186	Transcriptional regulator
ABE28_RS17015	COG0281	malic enzyme
ABE28_RS17020	COG0587	DNA-directed DNA polymerase activity
ABE28_RS17035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABE28_RS17045	COG4109	DRTGG domain
ABE28_RS17065	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABE28_RS17070	COG0006	proline dipeptidase activity
ABE28_RS17080	COG0589	response to stress
ABE28_RS17085	COG0165	Argininosuccinate lyase
ABE28_RS17090	COG0137	argininosuccinate synthase activity
ABE28_RS17100	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABE28_RS17105	COG2217	Heavy metal translocating P-type atpase
ABE28_RS17110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABE28_RS17115	COG0827	DNA restriction-modification system
ABE28_RS17120	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ABE28_RS17130	COG3874	Sporulation protein YtfJ
ABE28_RS17140	COG1714	RDD family
ABE28_RS17145	COG0616	signal peptide processing
ABE28_RS17150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ABE28_RS17170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABE28_RS17185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABE28_RS17195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABE28_RS17205	COG2962	Rard protein
ABE28_RS17210	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ABE28_RS17215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABE28_RS17225	COG0301	tRNA thio-modification
ABE28_RS17230	COG1104	cysteine desulfurase activity
ABE28_RS17240	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ABE28_RS17245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ABE28_RS17250	COG1309	transcriptional regulator
ABE28_RS17255	COG1956	GAF domain-containing protein
ABE28_RS17260	COG2203	Gaf domain
ABE28_RS17260	COG2199	diguanylate cyclase activity
ABE28_RS17265	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABE28_RS17300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABE28_RS17305	COG0454	-acetyltransferase
ABE28_RS17310	COG0517	IMP dehydrogenase activity
ABE28_RS17315	COG0123	including yeast histone deacetylase and acetoin utilization protein
ABE28_RS17325	COG1609	Transcriptional regulator
ABE28_RS17330	COG1605	Chorismate mutase
ABE28_RS17330	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ABE28_RS17335	COG0849	cell division
ABE28_RS17345	COG3118	belongs to the thioredoxin family
ABE28_RS17350	COG4980	gas vesicle protein
ABE28_RS17355	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ABE28_RS17360	COG2309	aminopeptidase activity
ABE28_RS17365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABE28_RS17370	COG1674	ftsk spoiiie
ABE28_RS17375	COG1473	amidohydrolase
ABE28_RS17380	COG4848	Belongs to the UPF0354 family
ABE28_RS17385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABE28_RS17400	COG2207	Transcriptional regulator
ABE28_RS17400	COG3708	Transcriptional regulator
ABE28_RS17405	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ABE28_RS17410	COG1363	Peptidase, m42
ABE28_RS17420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS17425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABE28_RS17435	COG0510	thiamine kinase activity
ABE28_RS17445	COG1597	lipid kinase activity
ABE28_RS17460	COG1914	H( )-stimulated, divalent metal cation uptake system
ABE28_RS17475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABE28_RS17485	COG0586	Pfam SNARE associated Golgi protein
ABE28_RS17510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABE28_RS17510	COG1587	Uroporphyrinogen-III synthase
ABE28_RS17515	COG1587	Uroporphyrinogen-III synthase
ABE28_RS17530	COG0039	L-malate dehydrogenase activity
ABE28_RS17535	COG1620	l-lactate permease
ABE28_RS17540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABE28_RS17550	COG1309	transcriptional regulator
ABE28_RS17555	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS17565	COG0701	Predicted permease
ABE28_RS17580	COG2824	Alkylphosphonate utilization operon protein PhnA
ABE28_RS17585	COG0745	RESPONSE REGULATOR receiver
ABE28_RS17590	COG0642	Histidine kinase
ABE28_RS17595	COG1136	(ABC) transporter
ABE28_RS17600	COG0577	efflux transmembrane transporter activity
ABE28_RS17610	COG0492	ferredoxin-NADP+ reductase activity
ABE28_RS17645	COG3842	ATPase activity
ABE28_RS17650	COG1349	DNA-binding transcription factor activity
ABE28_RS17655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABE28_RS17660	COG2169	Transcriptional regulator
ABE28_RS17660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABE28_RS17670	COG1349	DNA-binding transcription factor activity
ABE28_RS17675	COG1187	pseudouridine synthase activity
ABE28_RS17680	COG2244	polysaccharide biosynthetic process
ABE28_RS17685	COG2081	HI0933 family
ABE28_RS17700	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS17715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ABE28_RS17720	COG2814	Major facilitator Superfamily
ABE28_RS17725	COG3848	Pyruvate phosphate dikinase
ABE28_RS17725	COG0574	Belongs to the PEP-utilizing enzyme family
ABE28_RS17740	COG0656	L-ascorbic acid biosynthetic process
ABE28_RS17745	COG2814	Major facilitator Superfamily
ABE28_RS17750	COG1733	regulation of RNA biosynthetic process
ABE28_RS17765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ABE28_RS17770	COG1647	Serine aminopeptidase, S33
ABE28_RS17790	COG1309	transcriptional regulator
ABE28_RS17800	COG0602	queuosine metabolic process
ABE28_RS17805	COG0720	synthase
ABE28_RS17815	COG0840	transmembrane signaling receptor activity
ABE28_RS17845	COG4195	phage-related replication protein
ABE28_RS17850	COG0791	NLP P60 protein
ABE28_RS17860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABE28_RS17865	COG0840	transmembrane signaling receptor activity
ABE28_RS17875	COG2318	DinB family
ABE28_RS17900	COG0456	acetyltransferase
ABE28_RS17905	COG2002	toxin-antitoxin pair type II binding
ABE28_RS17910	COG0697	spore germination
ABE28_RS17915	COG2076	Multidrug Resistance protein
ABE28_RS17920	COG2076	Multidrug Resistance protein
ABE28_RS17930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABE28_RS17940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABE28_RS17950	COG0697	spore germination
ABE28_RS17955	COG0586	Pfam SNARE associated Golgi protein
ABE28_RS17960	COG0671	phosphoesterase, PA-phosphatase related
ABE28_RS17980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABE28_RS17985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABE28_RS17990	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS18000	COG3829	transcription factor binding
ABE28_RS18010	COG2514	catechol 2,3-dioxygenase activity
ABE28_RS18015	COG2259	Doxx family
ABE28_RS18025	COG0534	Mate efflux family protein
ABE28_RS18035	COG0444	Belongs to the ABC transporter superfamily
ABE28_RS18040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS18060	COG1126	abc transporter atp-binding protein
ABE28_RS18065	COG0765	amino acid transport
ABE28_RS18070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS18075	COG1309	transcriptional regulator
ABE28_RS18080	COG0246	Mannitol dehydrogenase
ABE28_RS18085	COG3711	transcriptional antiterminator
ABE28_RS18090	COG2213	PTS system mannitol-specific
ABE28_RS18090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABE28_RS18095	COG2851	Citrate transporter
ABE28_RS18100	COG0024	Methionine aminopeptidase
ABE28_RS18105	COG4565	transcriptional regulatory protein
ABE28_RS18110	COG3290	protein histidine kinase activity
ABE28_RS18115	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ABE28_RS18120	COG2169	Transcriptional regulator
ABE28_RS18125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABE28_RS18145	COG3142	Participates in the control of copper homeostasis
ABE28_RS18150	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS18160	COG0789	Transcriptional regulator
ABE28_RS18165	COG1357	PFAM Pentapeptide repeats (8 copies)
ABE28_RS18175	COG2746	aminoglycoside 3-N-acetyltransferase activity
ABE28_RS18185	COG1823	symporter activity
ABE28_RS18205	COG1113	amino acid transport
ABE28_RS18215	COG0785	Cytochrome C biogenesis protein
ABE28_RS18230	COG2197	response regulator
ABE28_RS18235	COG4585	Histidine kinase
ABE28_RS18245	COG1842	Phage shock protein A
ABE28_RS18255	COG1309	transcriptional regulator
ABE28_RS18260	COG3844	kynureninase activity
ABE28_RS18265	COG1113	amino acid transport
ABE28_RS18270	COG3483	tryptophan 2,3-dioxygenase activity
ABE28_RS18275	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ABE28_RS18285	COG1280	lysine exporter protein (LysE YggA)
ABE28_RS18295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABE28_RS18310	COG0716	FMN binding
ABE28_RS18315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABE28_RS18330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABE28_RS18340	COG1136	(ABC) transporter
ABE28_RS18340	COG0577	efflux transmembrane transporter activity
ABE28_RS18365	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS18375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABE28_RS18380	COG0583	DNA-binding transcription factor activity
ABE28_RS18385	COG1511	domain protein
ABE28_RS18390	COG2258	MOSC domain
ABE28_RS18395	COG2814	Major facilitator Superfamily
ABE28_RS18400	COG1309	transcriptional regulator
ABE28_RS18405	COG1113	amino acid transport
ABE28_RS18410	COG2814	Major facilitator Superfamily
ABE28_RS18415	COG1280	lysine exporter protein (LysE YggA)
ABE28_RS18420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABE28_RS18440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABE28_RS18445	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABE28_RS18450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABE28_RS18455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABE28_RS18470	COG1509	lysine 2,3-aminomutase activity
ABE28_RS18475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABE28_RS18480	COG3829	transcription factor binding
ABE28_RS18490	COG1876	peptidase activity
ABE28_RS18495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABE28_RS18500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABE28_RS18505	COG2610	gluconate transmembrane transporter activity
ABE28_RS18510	COG3290	protein histidine kinase activity
ABE28_RS18510	COG3829	transcription factor binding
ABE28_RS18515	COG0183	Belongs to the thiolase family
ABE28_RS18520	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS18550	COG3011	Protein conserved in bacteria
ABE28_RS18590	COG2610	gluconate transmembrane transporter activity
ABE28_RS18595	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS18600	COG2610	gluconate transmembrane transporter activity
ABE28_RS18605	COG0583	DNA-binding transcription factor activity
ABE28_RS18610	COG0604	alcohol dehydrogenase
ABE28_RS18615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABE28_RS18635	COG1376	ErfK ybiS ycfS ynhG family protein
ABE28_RS18660	COG4989	oxidoreductase activity
ABE28_RS18665	COG0840	transmembrane signaling receptor activity
ABE28_RS18665	COG5278	phosphoserine phosphatase activity
ABE28_RS18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABE28_RS18675	COG0697	spore germination
ABE28_RS18690	COG0494	nUDIX hydrolase
ABE28_RS18705	COG5444	nuclease activity
ABE28_RS18715	COG0477	Major facilitator Superfamily
ABE28_RS18745	COG5444	nuclease activity
ABE28_RS18755	COG0477	Major facilitator Superfamily
ABE28_RS18785	COG5444	nuclease activity
ABE28_RS18790	COG2814	Major facilitator Superfamily
ABE28_RS18800	COG1132	(ABC) transporter
ABE28_RS18810	COG1120	ATPase activity
ABE28_RS18815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS18820	COG1464	Belongs to the NlpA lipoprotein family
ABE28_RS18830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABE28_RS18835	COG2819	hydrolase of the alpha beta superfamily
ABE28_RS18845	COG0156	8-amino-7-oxononanoate synthase activity
ABE28_RS18855	COG2205	protein histidine kinase activity
ABE28_RS18860	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABE28_RS18870	COG3973	AAA domain
ABE28_RS18905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABE28_RS18920	COG2721	sulfolactate sulfo-lyase activity
ABE28_RS18930	COG2721	sulfolactate sulfo-lyase activity
ABE28_RS18945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABE28_RS18950	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS18955	COG1414	Transcriptional regulator
ABE28_RS19000	COG5577	PFAM Coat F domain
ABE28_RS19015	COG2602	Beta-lactamase
ABE28_RS19055	COG1051	belongs to the nudix hydrolase family
ABE28_RS19090	COG2814	Major facilitator Superfamily
ABE28_RS19105	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS19110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ABE28_RS19110	COG1605	Chorismate mutase
ABE28_RS19115	COG0077	Prephenate dehydratase
ABE28_RS19120	COG1917	Cupin 2, conserved barrel domain protein
ABE28_RS19135	COG2814	Major facilitator Superfamily
ABE28_RS19140	COG0436	Aminotransferase
ABE28_RS19160	COG1464	Belongs to the NlpA lipoprotein family
ABE28_RS19165	COG2011	ABC-type metal ion transport system permease component
ABE28_RS19170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABE28_RS19195	COG0154	amidase activity
ABE28_RS19205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABE28_RS19230	COG0596	Alpha beta hydrolase
ABE28_RS19240	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS19245	COG1454	alcohol dehydrogenase
ABE28_RS19250	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS19255	COG1609	Transcriptional regulator
ABE28_RS19280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABE28_RS19285	COG0477	Major facilitator Superfamily
ABE28_RS19295	COG1966	Carbon starvation protein
ABE28_RS19300	COG3279	Response regulator of the LytR AlgR family
ABE28_RS19305	COG3275	phosphorelay sensor kinase activity
ABE28_RS19310	COG1193	negative regulation of DNA recombination
ABE28_RS19320	COG2271	Major facilitator Superfamily
ABE28_RS19325	COG1473	amidohydrolase
ABE28_RS19330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABE28_RS19335	COG3842	ATPase activity
ABE28_RS19340	COG1176	ABC-type spermidine putrescine transport system, permease component I
ABE28_RS19365	COG1263	PTS System
ABE28_RS19365	COG2190	(PTS) system
ABE28_RS19365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ABE28_RS19370	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ABE28_RS19375	COG1027	Aspartate ammonia-lyase
ABE28_RS19405	COG2233	PERMEase
ABE28_RS19410	COG0402	S-adenosylhomocysteine deaminase activity
ABE28_RS19415	COG0402	S-adenosylhomocysteine deaminase activity
ABE28_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
ABE28_RS19425	COG0747	negative chemotaxis
ABE28_RS19430	COG0402	S-adenosylhomocysteine deaminase activity
ABE28_RS19435	COG0402	S-adenosylhomocysteine deaminase activity
ABE28_RS19440	COG0747	negative chemotaxis
ABE28_RS19445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS19455	COG0444	Belongs to the ABC transporter superfamily
ABE28_RS19460	COG4608	Belongs to the ABC transporter superfamily
ABE28_RS19465	COG2972	Histidine kinase
ABE28_RS19470	COG2207	Transcriptional regulator
ABE28_RS19480	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABE28_RS19500	COG2385	sporulation resulting in formation of a cellular spore
ABE28_RS19515	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABE28_RS19520	COG1289	transmembrane transporter activity
ABE28_RS19525	COG0583	DNA-binding transcription factor activity
ABE28_RS19625	COG0583	DNA-binding transcription factor activity
ABE28_RS19635	COG0697	spore germination
ABE28_RS19640	COG0697	spore germination
ABE28_RS19645	COG1053	succinate dehydrogenase
ABE28_RS19650	COG0583	DNA-binding transcription factor activity
ABE28_RS19660	COG2851	Citrate transporter
ABE28_RS19665	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS19675	COG0662	Cupin 2, conserved barrel domain protein
ABE28_RS19705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABE28_RS19710	COG3773	Cell wall hydrolase
ABE28_RS19720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABE28_RS19725	COG1845	cytochrome c oxidase, subunit III
ABE28_RS19765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABE28_RS19795	COG4319	ketosteroid isomerase
ABE28_RS19870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABE28_RS19880	COG1522	sequence-specific DNA binding
ABE28_RS19895	COG1252	NADH dehydrogenase
ABE28_RS19905	COG0018	arginyl-trna synthetase
ABE28_RS19910	COG2197	response regulator
ABE28_RS19915	COG3239	Fatty acid desaturase
ABE28_RS19920	COG3858	chitin binding
ABE28_RS19925	COG0697	spore germination
ABE28_RS19930	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
ABE28_RS19945	COG1309	transcriptional regulator
ABE28_RS19975	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ABE28_RS19980	COG1131	(ABC) transporter
ABE28_RS19990	COG3584	3D domain protein
ABE28_RS19990	COG3583	domain protein
ABE28_RS20000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABE28_RS20020	COG2017	converts alpha-aldose to the beta-anomer
ABE28_RS20035	COG3250	beta-galactosidase activity
ABE28_RS20040	COG1609	Transcriptional regulator
ABE28_RS20045	COG0395	ABC-type sugar transport system, permease component
ABE28_RS20055	COG2182	Extracellular solute-binding protein
ABE28_RS20060	COG2368	4-hydroxyphenylacetate
ABE28_RS20065	COG1028	Short-chain dehydrogenase reductase Sdr
ABE28_RS20075	COG1114	Component of the transport system for branched-chain amino acids
ABE28_RS20090	COG1760	l-serine dehydratase
ABE28_RS20095	COG1760	l-serine dehydratase
ABE28_RS20100	COG2311	Membrane
ABE28_RS20105	COG2356	endonuclease I
ABE28_RS20110	COG0737	Belongs to the 5'-nucleotidase family
ABE28_RS20120	COG1119	ATPase activity
ABE28_RS20125	COG0697	spore germination
ABE28_RS20130	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABE28_RS20140	COG4978	Transcriptional regulator
ABE28_RS20140	COG0789	Transcriptional regulator
ABE28_RS20145	COG0456	acetyltransferase
ABE28_RS20160	COG1309	transcriptional regulator
ABE28_RS20175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABE28_RS20180	COG0569	domain protein
ABE28_RS20185	COG1366	Belongs to the anti-sigma-factor antagonist family
ABE28_RS20200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABE28_RS20205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABE28_RS20205	COG0463	Glycosyl transferase, family 2
ABE28_RS20210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABE28_RS20215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABE28_RS20220	COG2910	NAD(P)H-binding
ABE28_RS20225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ABE28_RS20235	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS20240	COG4193	domain, Protein
ABE28_RS20245	COG2112	serine threonine protein kinase
ABE28_RS20255	COG3832	glyoxalase III activity
ABE28_RS20260	COG0640	Transcriptional regulator
ABE28_RS20265	COG1511	domain protein
ABE28_RS20270	COG1959	2 iron, 2 sulfur cluster binding
ABE28_RS20275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABE28_RS20290	COG4122	O-methyltransferase activity
ABE28_RS20320	COG0346	lactoylglutathione lyase activity
ABE28_RS20330	COG1846	Transcriptional regulator
ABE28_RS20335	COG2814	Major facilitator Superfamily
ABE28_RS20350	COG1131	(ABC) transporter
ABE28_RS20360	COG0702	epimerase
ABE28_RS20370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ABE28_RS20370	COG0456	acetyltransferase
ABE28_RS20375	COG0154	amidase activity
ABE28_RS20380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ABE28_RS20400	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ABE28_RS20405	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABE28_RS20410	COG1910	domain protein
ABE28_RS20415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ABE28_RS20430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ABE28_RS20435	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ABE28_RS20445	COG0612	Peptidase, M16
ABE28_RS20485	COG3104	oligopeptide transport
ABE28_RS20500	COG1595	DNA-templated transcription, initiation
ABE28_RS20505	COG0726	polysaccharide deacetylase
ABE28_RS20530	COG4548	von Willebrand factor, type A
ABE28_RS20535	COG0714	Associated with various cellular activities
ABE28_RS20540	COG0702	epimerase
ABE28_RS20545	COG5566	PFAM Mor transcription activator
ABE28_RS20555	COG1741	Belongs to the pirin family
ABE28_RS20570	COG0493	'glutamate synthase
ABE28_RS20575	COG0067	glutamate synthase
ABE28_RS20575	COG0070	glutamate synthase
ABE28_RS20575	COG0069	glutamate synthase activity
ABE28_RS20580	COG0583	DNA-binding transcription factor activity
ABE28_RS20610	COG1404	Belongs to the peptidase S8 family
ABE28_RS20615	COG0495	leucyl-tRNA aminoacylation
ABE28_RS20625	COG4282	regulation of fungal-type cell wall biogenesis
ABE28_RS20630	COG1242	4 iron, 4 sulfur cluster binding
ABE28_RS20635	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ABE28_RS20645	COG2267	carboxylic ester hydrolase activity
ABE28_RS20650	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABE28_RS20655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ABE28_RS20680	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABE28_RS20685	COG0840	transmembrane signaling receptor activity
ABE28_RS20685	COG5278	phosphoserine phosphatase activity
ABE28_RS20705	COG1506	peptidase
ABE28_RS20710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABE28_RS20715	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS20725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABE28_RS20730	COG1116	anion transmembrane transporter activity
ABE28_RS20735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABE28_RS20740	COG0494	nUDIX hydrolase
ABE28_RS20755	COG0783	Belongs to the Dps family
ABE28_RS20760	COG1854	S-ribosylhomocysteine lyase activity
ABE28_RS20765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ABE28_RS20770	COG3443	Belongs to the bacterial solute-binding protein 9 family
ABE28_RS20770	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABE28_RS20775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ABE28_RS20780	COG3290	protein histidine kinase activity
ABE28_RS20790	COG4948	Mandelate Racemase Muconate Lactonizing
ABE28_RS20795	COG0318	PFAM AMP-dependent synthetase and ligase
ABE28_RS20800	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ABE28_RS20805	COG0596	Alpha beta hydrolase
ABE28_RS20810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ABE28_RS20815	COG1169	isochorismate synthase
ABE28_RS20820	COG1575	Belongs to the MenA family. Type 1 subfamily
ABE28_RS20825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABE28_RS20965	COG1285	pathogenesis
ABE28_RS20975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABE28_RS20990	COG0506	proline dehydrogenase activity
ABE28_RS20995	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS21005	COG2508	Transcriptional regulator
ABE28_RS21010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABE28_RS21015	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ABE28_RS21020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABE28_RS21025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ABE28_RS21030	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ABE28_RS21040	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ABE28_RS21055	COG1994	Peptidase M50
ABE28_RS21060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABE28_RS21065	COG0833	amino acid
ABE28_RS21090	COG1472	Belongs to the glycosyl hydrolase 3 family
ABE28_RS21100	COG1378	Sugar-specific transcriptional regulator TrmB
ABE28_RS21115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABE28_RS21120	COG0604	alcohol dehydrogenase
ABE28_RS21125	COG3773	Cell wall hydrolase
ABE28_RS21130	COG3906	Belongs to the UPF0473 family
ABE28_RS21135	COG0346	lactoylglutathione lyase activity
ABE28_RS21140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ABE28_RS21145	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ABE28_RS21150	COG0523	cobalamin synthesis protein
ABE28_RS21155	COG0322	excinuclease ABC activity
ABE28_RS21165	COG1785	Belongs to the alkaline phosphatase family
ABE28_RS21170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ABE28_RS21185	COG0753	catalase activity
ABE28_RS21200	COG1950	PFAM Membrane protein of
ABE28_RS21205	COG2356	endonuclease I
ABE28_RS21210	COG1113	amino acid transport
ABE28_RS21220	COG0737	Belongs to the 5'-nucleotidase family
ABE28_RS21225	COG2318	DinB family
ABE28_RS21235	COG1191	sigma factor activity
ABE28_RS21270	COG2814	Major facilitator Superfamily
ABE28_RS21275	COG0531	amino acid
ABE28_RS21280	COG1968	undecaprenyl-diphosphatase activity
ABE28_RS21285	COG0584	glycerophosphoryl diester phosphodiesterase
ABE28_RS21295	COG3858	chitin binding
ABE28_RS21295	COG1388	LysM domain
ABE28_RS21300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABE28_RS21315	COG0166	Belongs to the GPI family
ABE28_RS21320	COG1979	alcohol dehydrogenase
ABE28_RS21325	COG2155	Conserved Protein
ABE28_RS21330	COG1098	S1 RNA binding domain
ABE28_RS21340	COG0436	Aminotransferase
ABE28_RS21345	COG1522	sequence-specific DNA binding
ABE28_RS21350	COG2267	carboxylic ester hydrolase activity
ABE28_RS21360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ABE28_RS21375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS21380	COG1120	ATPase activity
ABE28_RS21385	COG0748	coenzyme F420 binding
ABE28_RS21410	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABE28_RS21425	COG0456	acetyltransferase
ABE28_RS21435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABE28_RS21445	COG5018	Exonuclease
ABE28_RS21450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABE28_RS21465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABE28_RS21465	COG2111	Na H antiporter
ABE28_RS21470	COG2111	Na H antiporter
ABE28_RS21475	COG1006	Multisubunit Na H antiporter MnhC subunit
ABE28_RS21480	COG0651	ATP synthesis coupled electron transport
ABE28_RS21485	COG1863	multisubunit Na H antiporter MnhE subunit
ABE28_RS21490	COG2212	antiporter activity
ABE28_RS21495	COG1320	monovalent cation:proton antiporter activity
ABE28_RS21505	COG2050	protein possibly involved in aromatic compounds catabolism
ABE28_RS21520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABE28_RS21520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABE28_RS21525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABE28_RS21525	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABE28_RS21535	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ABE28_RS21540	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ABE28_RS21550	COG3584	3D domain protein
ABE28_RS21565	COG1252	NADH dehydrogenase
ABE28_RS21570	COG0492	ferredoxin-NADP+ reductase activity
ABE28_RS21580	COG0316	Belongs to the HesB IscA family
ABE28_RS21590	COG4844	belongs to the
ABE28_RS21595	COG1252	NADH dehydrogenase
ABE28_RS21600	COG4837	Protein of unknown function (DUF1462)
ABE28_RS21605	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ABE28_RS21610	COG0083	homoserine kinase activity
ABE28_RS21615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABE28_RS21620	COG0460	homoserine dehydrogenase
ABE28_RS21630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABE28_RS21635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABE28_RS21640	COG2801	Transposase and inactivated derivatives
ABE28_RS21650	COG0647	UMP catabolic process
ABE28_RS21655	COG2445	Protein of unknown function DUF86
ABE28_RS21670	COG4470	Protein conserved in bacteria
ABE28_RS21680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABE28_RS21685	COG0739	heme binding
ABE28_RS21700	COG3377	Domain of unknown function (DUF1805)
ABE28_RS21705	COG0737	Belongs to the 5'-nucleotidase family
ABE28_RS21710	COG0730	response to heat
ABE28_RS21715	COG1801	Protein of unknown function DUF72
ABE28_RS21725	COG0719	Fe-S assembly protein
ABE28_RS21730	COG0822	iron-sulfur transferase activity
ABE28_RS21735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABE28_RS21740	COG0719	Fe-S assembly protein
ABE28_RS21745	COG0396	ATPase activity
ABE28_RS21760	COG2801	Transposase and inactivated derivatives
ABE28_RS21765	COG1464	Belongs to the NlpA lipoprotein family
ABE28_RS21770	COG2011	ABC-type metal ion transport system permease component
ABE28_RS21775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABE28_RS21780	COG2873	o-acetylhomoserine
ABE28_RS21785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ABE28_RS21790	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ABE28_RS21795	COG0509	glycine decarboxylation via glycine cleavage system
ABE28_RS21800	COG1393	Belongs to the ArsC family
ABE28_RS21805	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS21810	COG0183	Belongs to the thiolase family
ABE28_RS21815	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS21815	COG1024	Enoyl-CoA hydratase
ABE28_RS21835	COG5577	PFAM Coat F domain
ABE28_RS21845	COG0772	Belongs to the SEDS family
ABE28_RS21850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABE28_RS21855	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABE28_RS21855	COG1321	iron dependent repressor
ABE28_RS21860	COG1121	(ABC) transporter
ABE28_RS21865	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABE28_RS21870	COG1609	Transcriptional regulator
ABE28_RS21875	COG0833	amino acid
ABE28_RS21880	COG0366	Alpha amylase catalytic
ABE28_RS21925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABE28_RS21930	COG1368	sulfuric ester hydrolase activity
ABE28_RS21935	COG4607	ABC-type enterochelin transport system periplasmic component
ABE28_RS21940	COG4604	ABC transporter, ATP-binding protein
ABE28_RS21945	COG4605	iron ion homeostasis
ABE28_RS21950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS21965	COG1657	PFAM Prenyltransferase squalene oxidase
ABE28_RS21990	COG3850	Histidine kinase
ABE28_RS21990	COG5002	protein histidine kinase activity
ABE28_RS21995	COG0745	RESPONSE REGULATOR receiver
ABE28_RS22000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABE28_RS22005	COG2197	response regulator
ABE28_RS22010	COG4585	Histidine kinase
ABE28_RS22020	COG0583	DNA-binding transcription factor activity
ABE28_RS22025	COG5609	conserved protein (DUF2294)
ABE28_RS22030	COG3383	formate dehydrogenase (NAD+) activity
ABE28_RS22035	COG2427	Protein of unknown function (DUF1641)
ABE28_RS22075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ABE28_RS22080	COG0557	exoribonuclease II activity
ABE28_RS22085	COG1647	Serine aminopeptidase, S33
ABE28_RS22090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ABE28_RS22100	COG1876	peptidase activity
ABE28_RS22130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABE28_RS22140	COG0126	phosphoglycerate kinase activity
ABE28_RS22145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABE28_RS22160	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ABE28_RS22170	COG0740	serine-type endopeptidase activity
ABE28_RS22175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABE28_RS22185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ABE28_RS22190	COG1660	Displays ATPase and GTPase activities
ABE28_RS22195	COG1051	belongs to the nudix hydrolase family
ABE28_RS22200	COG0492	ferredoxin-NADP+ reductase activity
ABE28_RS22205	COG0457	Tetratricopeptide repeat
ABE28_RS22210	COG1012	belongs to the aldehyde dehydrogenase family
ABE28_RS22215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABE28_RS22215	COG0140	phosphoribosyl-ATP diphosphatase activity
ABE28_RS22220	COG0107	imidazoleglycerol-phosphate synthase activity
ABE28_RS22225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ABE28_RS22230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABE28_RS22235	COG0131	Imidazoleglycerol-phosphate dehydratase
ABE28_RS22240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABE28_RS22245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABE28_RS22250	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ABE28_RS22260	COG3764	Sortase (surface protein transpeptidase)
ABE28_RS22265	COG0110	maltose O-acetyltransferase activity
ABE28_RS22270	COG0546	phosphoglycolate phosphatase activity
ABE28_RS22275	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABE28_RS22280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ABE28_RS22290	COG5646	InterPro IPR014922
ABE28_RS22295	COG3595	metallopeptidase activity
ABE28_RS22300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABE28_RS22305	COG0556	nucleotide-excision repair
ABE28_RS22310	COG4897	Protein conserved in bacteria
ABE28_RS22315	COG0753	catalase activity
ABE28_RS22325	COG2353	YceI-like domain
ABE28_RS22330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS22335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS22340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS22345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABE28_RS22350	COG0793	Belongs to the peptidase S41A family
ABE28_RS22350	COG3409	Peptidoglycan-binding domain 1 protein
ABE28_RS22355	COG3883	PFAM NLP P60 protein
ABE28_RS22355	COG0791	NLP P60 protein
ABE28_RS22360	COG2177	Part of the ABC transporter FtsEX involved in
ABE28_RS22365	COG2884	Cell division ATP-binding protein ftsE
ABE28_RS22375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ABE28_RS22380	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ABE28_RS22385	COG0653	protein targeting
ABE28_RS22390	COG1396	sequence-specific DNA binding
ABE28_RS22400	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ABE28_RS22410	COG1516	flagellar protein fliS
ABE28_RS22415	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ABE28_RS22420	COG1334	flagellar protein FlaG
ABE28_RS22435	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ABE28_RS22440	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ABE28_RS22450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ABE28_RS22455	COG4786	Flagellar basal body rod
ABE28_RS22455	COG1256	bacterial-type flagellum assembly
ABE28_RS22465	COG2747	anti-sigma28 factor FlgM
ABE28_RS22475	COG1040	competence protein
ABE28_RS22485	COG1307	EDD domain protein, DegV family
ABE28_RS22490	COG2197	response regulator
ABE28_RS22495	COG4585	Histidine kinase
ABE28_RS22500	COG1739	Uncharacterized protein family UPF0029
ABE28_RS22505	COG1316	TRANSCRIPTIONal
ABE28_RS22510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABE28_RS22515	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS22530	COG0728	peptidoglycan biosynthetic process
ABE28_RS22535	COG0438	transferase activity, transferring glycosyl groups
ABE28_RS22540	COG1134	teichoic acid transport
ABE28_RS22545	COG1682	transport, permease protein
ABE28_RS22550	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABE28_RS22555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABE28_RS22560	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ABE28_RS22565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ABE28_RS22570	COG0791	NLP P60 protein
ABE28_RS22570	COG1388	LysM domain
ABE28_RS22575	COG1316	TRANSCRIPTIONal
ABE28_RS22580	COG1368	sulfuric ester hydrolase activity
ABE28_RS22590	COG0653	protein targeting
ABE28_RS22595	COG1511	domain protein
ABE28_RS22595	COG1511	domain protein
ABE28_RS22600	COG1785	Belongs to the alkaline phosphatase family
ABE28_RS22605	COG2385	sporulation resulting in formation of a cellular spore
ABE28_RS22605	COG2247	cell wall binding repeat
ABE28_RS22610	COG0768	penicillin binding
ABE28_RS22630	COG4715	Zinc finger, swim domain protein
ABE28_RS22635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ABE28_RS22640	COG1279	arginine transmembrane transporter activity
ABE28_RS22645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABE28_RS22665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABE28_RS22670	COG0601	transmembrane transport
ABE28_RS22675	COG0747	negative chemotaxis
ABE28_RS22680	COG4608	Belongs to the ABC transporter superfamily
ABE28_RS22685	COG0444	Belongs to the ABC transporter superfamily
ABE28_RS22695	COG0629	single-stranded DNA binding
ABE28_RS22720	COG4786	Flagellar basal body rod
ABE28_RS22725	COG4786	Flagellar basal body rod
ABE28_RS22730	COG1077	Cell shape determining protein MreB Mrl
ABE28_RS22735	COG1609	Transcriptional regulator
ABE28_RS22740	COG0739	heme binding
ABE28_RS22750	COG2385	sporulation resulting in formation of a cellular spore
ABE28_RS22765	COG4836	Membrane
ABE28_RS22770	COG1007	ATP synthesis coupled electron transport
ABE28_RS22775	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABE28_RS22780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABE28_RS22785	COG0713	ATP synthesis coupled electron transport
ABE28_RS22795	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABE28_RS22800	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABE28_RS22810	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABE28_RS22815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABE28_RS22820	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABE28_RS22830	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ABE28_RS22835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ABE28_RS22845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABE28_RS22855	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ABE28_RS22860	COG0356	it plays a direct role in the translocation of protons across the membrane
ABE28_RS22870	COG1404	Belongs to the peptidase S8 family
ABE28_RS22875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ABE28_RS22880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ABE28_RS22895	COG0698	ribose 5-phosphate isomerase
ABE28_RS22900	COG0840	transmembrane signaling receptor activity
ABE28_RS22910	COG1971	Probably functions as a manganese efflux pump
ABE28_RS22915	COG0009	L-threonylcarbamoyladenylate synthase
ABE28_RS22930	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ABE28_RS22940	COG1435	thymidine kinase activity
ABE28_RS22950	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ABE28_RS22955	COG1494	fructose-1,6-bisphosphatase
ABE28_RS22960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABE28_RS22965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABE28_RS22975	COG2204	response regulator
ABE28_RS22980	COG4821	SIS domain
ABE28_RS22985	COG0504	CTP synthase activity
ABE28_RS22990	COG3343	RNA polymerase activity
ABE28_RS22995	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABE28_RS22995	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABE28_RS22995	COG1703	isobutyryl-CoA mutase activity
ABE28_RS23005	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS23010	COG1960	acyl-CoA dehydrogenase activity
ABE28_RS23015	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABE28_RS23020	COG0183	Belongs to the thiolase family
ABE28_RS23025	COG0247	lactate metabolic process
ABE28_RS23025	COG2181	nitrate reductase activity
ABE28_RS23030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABE28_RS23035	COG4294	response to UV
ABE28_RS23040	COG0018	arginyl-trna synthetase
ABE28_RS23045	COG4506	Protein conserved in bacteria
ABE28_RS23050	COG0010	Belongs to the arginase family
ABE28_RS23055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABE28_RS23060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABE28_RS23070	COG1994	Peptidase M50
ABE28_RS23080	COG3465	dGTPase activity
ABE28_RS23085	COG1078	dGTPase activity
ABE28_RS23100	COG0095	Lipoate-protein ligase
ABE28_RS23105	COG0280	phosphate acetyltransferase
ABE28_RS23110	COG3253	May function as heme-dependent peroxidase
ABE28_RS23120	COG2363	Small membrane protein
ABE28_RS23130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ABE28_RS23145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ABE28_RS23150	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ABE28_RS23155	COG0314	molybdopterin synthase activity
ABE28_RS23160	COG0746	molybdenum cofactor guanylyltransferase activity
ABE28_RS23165	COG0351	phosphomethylpyrimidine kinase
ABE28_RS23170	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ABE28_RS23180	COG2814	Major facilitator Superfamily
ABE28_RS23185	COG1846	Transcriptional regulator
ABE28_RS23195	COG0561	phosphatase activity
ABE28_RS23205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABE28_RS23225	COG2096	Adenosyltransferase
ABE28_RS23240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ABE28_RS23250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ABE28_RS23255	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ABE28_RS23260	COG1120	ATPase activity
ABE28_RS23265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABE28_RS23270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ABE28_RS23275	COG0726	polysaccharide deacetylase
ABE28_RS23300	COG1131	(ABC) transporter
ABE28_RS23325	COG0488	(ABC) transporter
ABE28_RS23350	COG2252	PERMEase
ABE28_RS23365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABE28_RS23365	COG0723	plastoquinol--plastocyanin reductase activity
ABE28_RS23370	COG4895	conserved protein (DUF2196)
ABE28_RS23380	COG0788	formyltetrahydrofolate deformylase activity
ABE28_RS23400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABE28_RS23405	COG0765	amino acid transport
ABE28_RS23415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABE28_RS23420	COG1366	Belongs to the anti-sigma-factor antagonist family
ABE28_RS23425	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABE28_RS23425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ABE28_RS23430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ABE28_RS23440	COG5002	protein histidine kinase activity
ABE28_RS23445	COG0745	RESPONSE REGULATOR receiver
ABE28_RS23450	COG1136	(ABC) transporter
ABE28_RS23450	COG0577	efflux transmembrane transporter activity
ABE28_RS23455	COG1136	(ABC) transporter
ABE28_RS23470	COG3162	membrane
ABE28_RS23475	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABE28_RS23500	COG2267	carboxylic ester hydrolase activity
ABE28_RS23505	COG1301	dicarboxylic acid transport
ABE28_RS23515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABE28_RS23525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABE28_RS23530	COG1879	ABC-type sugar transport system periplasmic component
ABE28_RS23535	COG1172	Belongs to the binding-protein-dependent transport system permease family
ABE28_RS23540	COG1129	ABC transporter
ABE28_RS23545	COG1869	D-ribose catabolic process
ABE28_RS23550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABE28_RS23555	COG1609	Transcriptional regulator
ABE28_RS23580	COG0076	glutamate decarboxylase activity
ABE28_RS23600	COG5337	Spore coat protein CotH
ABE28_RS23610	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABE28_RS23615	COG0753	catalase activity
ABE28_RS23615	COG0693	protein deglycase activity
ABE28_RS23630	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABE28_RS23635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABE28_RS23640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABE28_RS23645	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ABE28_RS23650	COG4853	Protein conserved in bacteria
ABE28_RS23660	COG5002	protein histidine kinase activity
ABE28_RS23665	COG0745	RESPONSE REGULATOR receiver
ABE28_RS23670	COG0741	lytic transglycosylase activity
ABE28_RS23670	COG1196	nuclear chromosome segregation
ABE28_RS23670	COG0739	heme binding
ABE28_RS23700	COG0305	Participates in initiation and elongation during chromosome replication
ABE28_RS23705	COG0359	binds to the 23S rRNA
ABE28_RS23710	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ABE28_RS23720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ABE28_RS23725	COG0629	single-stranded DNA binding
ABE28_RS23730	COG0360	Binds together with S18 to 16S ribosomal RNA
ABE28_RS23735	COG0012	GTP binding
ABE28_RS23740	COG4481	Protein conserved in bacteria
ABE28_RS23745	COG0668	transmembrane transport
ABE28_RS23760	COG1475	DNA binding
ABE28_RS23765	COG1192	Involved in chromosome partitioning
ABE28_RS23770	COG1475	DNA binding
ABE28_RS23775	COG0357	Ribosomal RNA small subunit methyltransferase G
ABE28_RS23780	COG0445	tRNA wobble uridine modification
ABE28_RS23790	COG1847	R3H domain protein
ABE28_RS23795	COG0706	membrane insertase activity
ABE28_RS23800	COG0594	ribonuclease P activity
ABE28_RS23805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ABE28_RS23810	COG0592	DNA-directed DNA polymerase activity
ABE28_RS23815	COG2501	S4 domain
ABE28_RS23820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABE28_RS23830	COG0187	DNA topoisomerase II activity
ABE28_RS23835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABE28_RS23840	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ABE28_RS23940	COG1774	PSP1 C-terminal conserved region
ABE28_RS23990	COG3584	3D domain protein
ABE28_RS23990	COG3583	domain protein
ABE28_RS24085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABE28_RS24090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABE28_RS24095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABE28_RS24165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABE28_RS24185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family