locus-tag	class	description
EXW31_RS00005	COG1192	Involved in chromosome partitioning
EXW31_RS00065	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS00170	COG3728	DNA packaging
EXW31_RS00170	COG5484	DNA packaging
EXW31_RS00280	COG1396	sequence-specific DNA binding
EXW31_RS00350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW31_RS00355	COG0592	DNA-directed DNA polymerase activity
EXW31_RS00360	COG2501	S4 domain
EXW31_RS00365	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW31_RS00370	COG0187	DNA topoisomerase II activity
EXW31_RS00375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW31_RS00410	COG0516	GMP reductase activity
EXW31_RS00410	COG0517	IMP dehydrogenase activity
EXW31_RS00415	COG1686	Belongs to the peptidase S11 family
EXW31_RS00425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW31_RS00445	COG1428	Deoxynucleoside kinase
EXW31_RS00450	COG1428	Deoxynucleoside kinase
EXW31_RS00455	COG1335	isochorismatase
EXW31_RS00460	COG0590	tRNA wobble adenosine to inosine editing
EXW31_RS00470	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW31_RS00475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW31_RS00480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW31_RS00525	COG1982	Orn Lys Arg decarboxylase major
EXW31_RS00530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW31_RS00535	COG0470	DNA polymerase III
EXW31_RS00540	COG1774	PSP1 C-terminal conserved region
EXW31_RS00545	COG4467	Involved in initiation control of chromosome replication
EXW31_RS00550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW31_RS00560	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW31_RS00565	COG2002	toxin-antitoxin pair type II binding
EXW31_RS00575	COG0084	hydrolase, TatD family'
EXW31_RS00585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW31_RS00595	COG4466	Protein conserved in bacteria
EXW31_RS00610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW31_RS00615	COG0251	oxidation-reduction process
EXW31_RS00620	COG2088	sporulation resulting in formation of a cellular spore
EXW31_RS00625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW31_RS00645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW31_RS00650	COG2002	toxin-antitoxin pair type II binding
EXW31_RS00655	COG2244	polysaccharide biosynthetic process
EXW31_RS00660	COG3956	TIGRFAM MazG family protein
EXW31_RS00665	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW31_RS00685	COG1098	S1 RNA binding domain
EXW31_RS00700	COG2208	phosphoserine phosphatase activity
EXW31_RS00710	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW31_RS00715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW31_RS00725	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW31_RS00730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW31_RS00735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW31_RS00740	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW31_RS00745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS00750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW31_RS00755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW31_RS00760	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW31_RS00765	COG1396	sequence-specific DNA binding
EXW31_RS00770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW31_RS00860	COG3880	PFAM UvrB UvrC protein
EXW31_RS00865	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW31_RS00870	COG0542	response to heat
EXW31_RS00875	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW31_RS00880	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW31_RS00885	COG4956	integral membrane protein (PIN domain superfamily)
EXW31_RS00890	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW31_RS00900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW31_RS00905	COG1045	serine acetyltransferase
EXW31_RS00910	COG0215	cysteine-tRNA ligase activity
EXW31_RS00920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW31_RS00925	COG3688	RNA-binding protein containing a PIN domain
EXW31_RS00935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW31_RS00940	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW31_RS00945	COG0250	Participates in transcription elongation, termination and antitermination
EXW31_RS00950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW31_RS00955	COG0081	regulation of translation
EXW31_RS00960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW31_RS00965	COG0222	ribosome binding
EXW31_RS00970	COG2813	Specifically methylates the guanine in position
EXW31_RS00975	COG0085	RNA polymerase activity
EXW31_RS00980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW31_RS00985	COG1358	cellular component organization or biogenesis
EXW31_RS00990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW31_RS00995	COG0049	tRNA binding
EXW31_RS01000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW31_RS01005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW31_RS01010	COG0051	transcription antitermination factor activity, RNA binding
EXW31_RS01015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW31_RS01020	COG0088	Forms part of the polypeptide exit tunnel
EXW31_RS01025	COG0089	rRNA binding
EXW31_RS01030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW31_RS01035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW31_RS01040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW31_RS01050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW31_RS01055	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW31_RS01060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW31_RS01065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW31_RS01070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW31_RS01075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW31_RS01085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW31_RS01095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW31_RS01105	COG1841	ribosomal large subunit assembly
EXW31_RS01110	COG0200	Binds to the 23S rRNA
EXW31_RS01115	COG0201	protein transport
EXW31_RS01120	COG0563	adenylate kinase activity
EXW31_RS01125	COG0024	Methionine aminopeptidase
EXW31_RS01135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW31_RS01140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW31_RS01145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW31_RS01170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW31_RS01180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW31_RS01185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW31_RS01195	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS01200	COG0489	protein tyrosine kinase activity
EXW31_RS01210	COG2194	sulfuric ester hydrolase activity
EXW31_RS01215	COG0726	polysaccharide deacetylase
EXW31_RS01295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW31_RS01300	COG4856	YbbR-like protein
EXW31_RS01350	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS01355	COG2011	ABC-type metal ion transport system permease component
EXW31_RS01365	COG1464	Belongs to the NlpA lipoprotein family
EXW31_RS01370	COG0604	alcohol dehydrogenase
EXW31_RS01380	COG0277	FAD linked oxidase domain protein
EXW31_RS01385	COG2271	Major facilitator Superfamily
EXW31_RS01395	COG2814	Major facilitator Superfamily
EXW31_RS01415	COG0601	transmembrane transport
EXW31_RS01420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW31_RS01425	COG0444	Belongs to the ABC transporter superfamily
EXW31_RS01430	COG4608	Belongs to the ABC transporter superfamily
EXW31_RS01435	COG4166	transmembrane transport
EXW31_RS01445	COG2207	Transcriptional regulator
EXW31_RS01460	COG4166	transmembrane transport
EXW31_RS01465	COG4166	transmembrane transport
EXW31_RS01470	COG0656	L-ascorbic acid biosynthetic process
EXW31_RS01475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW31_RS01485	COG4149	molybdate abc transporter
EXW31_RS01490	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW31_RS01495	COG1910	domain protein
EXW31_RS01510	COG0697	spore germination
EXW31_RS01525	COG0204	Acyl-transferase
EXW31_RS01535	COG1609	Transcriptional regulator
EXW31_RS01545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS01560	COG5298	Protein conserved in bacteria
EXW31_RS01580	COG0488	(ABC) transporter
EXW31_RS01590	COG0747	negative chemotaxis
EXW31_RS01595	COG0747	negative chemotaxis
EXW31_RS01600	COG0601	transmembrane transport
EXW31_RS01605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW31_RS01610	COG0444	Belongs to the ABC transporter superfamily
EXW31_RS01615	COG4608	Belongs to the ABC transporter superfamily
EXW31_RS01620	COG0561	phosphatase activity
EXW31_RS01650	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW31_RS01655	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW31_RS01665	COG0531	amino acid
EXW31_RS01670	COG2814	Major facilitator Superfamily
EXW31_RS01680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW31_RS01690	COG4294	response to UV
EXW31_RS01695	COG0705	Rhomboid family
EXW31_RS01700	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW31_RS01705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW31_RS01710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW31_RS01715	COG0864	Transcriptional regulator
EXW31_RS01720	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW31_RS01725	COG2183	response to ionizing radiation
EXW31_RS01825	COG0802	atpase or kinase
EXW31_RS01830	COG1214	PFAM Peptidase M22, glycoprotease
EXW31_RS01835	COG0456	acetyltransferase
EXW31_RS01845	COG0488	(ABC) transporter
EXW31_RS01850	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW31_RS01860	COG1266	CAAX protease self-immunity
EXW31_RS01865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW31_RS01870	COG0459	protein refolding
EXW31_RS01875	COG0519	Catalyzes the synthesis of GMP from XMP
EXW31_RS01875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW31_RS01880	COG2252	PERMEase
EXW31_RS01890	COG5002	protein histidine kinase activity
EXW31_RS01910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW31_RS01950	COG4187	Peptidase family M20/M25/M40
EXW31_RS01990	COG0697	spore germination
EXW31_RS02010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW31_RS02015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW31_RS02020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW31_RS02030	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW31_RS02035	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW31_RS02040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW31_RS02045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW31_RS02050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW31_RS02055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW31_RS02060	COG0138	bifunctional purine biosynthesis protein purh
EXW31_RS02065	COG0151	Belongs to the GarS family
EXW31_RS02085	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW31_RS02090	COG0210	DNA helicase
EXW31_RS02095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW31_RS02100	COG4851	CamS sex pheromone cAM373 precursor
EXW31_RS02110	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS02115	COG1335	isochorismatase
EXW31_RS02125	COG2011	ABC-type metal ion transport system permease component
EXW31_RS02130	COG1464	Belongs to the NlpA lipoprotein family
EXW31_RS02140	COG0003	Pfam Anion-transporting ATPase
EXW31_RS02145	COG1846	Transcriptional regulator
EXW31_RS02150	COG4682	membrane
EXW31_RS02160	COG0154	amidase activity
EXW31_RS02165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW31_RS02170	COG1597	lipid kinase activity
EXW31_RS02185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS02195	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS02200	COG2076	Multidrug Resistance protein
EXW31_RS02210	COG2309	aminopeptidase activity
EXW31_RS02230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS02240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW31_RS02250	COG4807	Protein conserved in bacteria
EXW31_RS02275	COG1757	Na H antiporter
EXW31_RS02280	COG1473	amidohydrolase
EXW31_RS02300	COG0450	alkyl hydroperoxide reductase
EXW31_RS02310	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW31_RS02320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS02325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS02330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS02335	COG0492	ferredoxin-NADP+ reductase activity
EXW31_RS02345	COG0166	Belongs to the GPI family
EXW31_RS02370	COG5002	protein histidine kinase activity
EXW31_RS02385	COG3541	Predicted nucleotidyltransferase
EXW31_RS02390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW31_RS02390	COG0723	plastoquinol--plastocyanin reductase activity
EXW31_RS02400	COG0765	amino acid transport
EXW31_RS02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS02410	COG1126	abc transporter atp-binding protein
EXW31_RS02415	COG0840	transmembrane signaling receptor activity
EXW31_RS02420	COG0277	FAD linked oxidase domain protein
EXW31_RS02425	COG0366	Alpha amylase catalytic
EXW31_RS02430	COG2190	(PTS) system
EXW31_RS02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS02430	COG1263	PTS System
EXW31_RS02450	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW31_RS02455	COG0352	thiamine-phosphate diphosphorylase activity
EXW31_RS02460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW31_RS02480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW31_RS02490	COG1116	anion transmembrane transporter activity
EXW31_RS02495	COG0488	(ABC) transporter
EXW31_RS02520	COG2270	Major facilitator Superfamily
EXW31_RS02550	COG2310	stress, protein
EXW31_RS02555	COG2310	stress, protein
EXW31_RS02560	COG2310	stress, protein
EXW31_RS02565	COG0861	Integral membrane protein TerC family
EXW31_RS02575	COG3853	Toxic anion resistance protein (TelA)
EXW31_RS02585	COG4840	Belongs to the UPF0435 family
EXW31_RS02590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW31_RS02600	COG1295	ribonuclease BN
EXW31_RS02605	COG2217	Heavy metal translocating P-type atpase
EXW31_RS02610	COG0697	spore germination
EXW31_RS02635	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS02650	COG3871	stress protein (general stress protein 26)
EXW31_RS02655	COG0387	Pfam Sodium calcium exchanger
EXW31_RS02665	COG0535	radical SAM domain protein
EXW31_RS02685	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW31_RS02705	COG3829	transcription factor binding
EXW31_RS02715	COG0833	amino acid
EXW31_RS02720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW31_RS02745	COG1263	PTS System
EXW31_RS02745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS02750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW31_RS02770	COG1216	Glycosyl transferase, family 2
EXW31_RS02780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW31_RS02780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW31_RS02800	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW31_RS02805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW31_RS02820	COG1228	amidohydrolase
EXW31_RS02825	COG1090	epimerase
EXW31_RS02830	COG2137	regulation of response to DNA damage stimulus
EXW31_RS02855	COG1988	membrane-bound metal-dependent
EXW31_RS02860	COG1194	a g-specific adenine glycosylase
EXW31_RS02880	COG3557	Belongs to the UPF0374 family
EXW31_RS02885	COG1132	(ABC) transporter
EXW31_RS02890	COG4129	membrane
EXW31_RS02895	COG0067	glutamate synthase
EXW31_RS02895	COG0069	glutamate synthase activity
EXW31_RS02895	COG0070	glutamate synthase
EXW31_RS02900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW31_RS02905	COG4555	ABC transporter
EXW31_RS02925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW31_RS02930	COG0735	belongs to the Fur family
EXW31_RS03045	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW31_RS03050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW31_RS03070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW31_RS03080	COG2766	serine protein kinase
EXW31_RS03085	COG2718	Belongs to the UPF0229 family
EXW31_RS03100	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW31_RS03105	COG2268	Band 7 protein
EXW31_RS03110	COG3290	protein histidine kinase activity
EXW31_RS03115	COG4565	transcriptional regulatory protein
EXW31_RS03120	COG2851	Citrate transporter
EXW31_RS03140	COG0745	RESPONSE REGULATOR receiver
EXW31_RS03145	COG5002	protein histidine kinase activity
EXW31_RS03155	COG4990	cell redox homeostasis
EXW31_RS03165	COG3290	protein histidine kinase activity
EXW31_RS03170	COG4565	transcriptional regulatory protein
EXW31_RS03175	COG3493	citrate carrier protein
EXW31_RS03180	COG0281	malic enzyme
EXW31_RS03190	COG0697	spore germination
EXW31_RS03195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS03205	COG5002	protein histidine kinase activity
EXW31_RS03210	COG0745	RESPONSE REGULATOR receiver
EXW31_RS03215	COG0456	acetyltransferase
EXW31_RS03220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW31_RS03225	COG3383	formate dehydrogenase (NAD+) activity
EXW31_RS03230	COG2427	Protein of unknown function (DUF1641)
EXW31_RS03250	COG0531	amino acid
EXW31_RS03260	COG0640	Transcriptional regulator
EXW31_RS03265	COG2217	Heavy metal translocating P-type atpase
EXW31_RS03270	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW31_RS03285	COG3227	Zinc metalloprotease (Elastase)
EXW31_RS03305	COG2720	vancomycin resistance protein
EXW31_RS03310	COG1316	TRANSCRIPTIONal
EXW31_RS03315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS03320	COG0346	lactoylglutathione lyase activity
EXW31_RS03325	COG1253	flavin adenine dinucleotide binding
EXW31_RS03330	COG1027	Aspartate ammonia-lyase
EXW31_RS03335	COG1620	l-lactate permease
EXW31_RS03340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW31_RS03355	COG3104	oligopeptide transport
EXW31_RS03360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS03365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS03370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS03385	COG0156	8-amino-7-oxononanoate synthase activity
EXW31_RS03390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW31_RS03395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW31_RS03405	COG4548	von Willebrand factor, type A
EXW31_RS03410	COG0714	Associated with various cellular activities
EXW31_RS03435	COG0531	amino acid
EXW31_RS03440	COG2188	Transcriptional regulator
EXW31_RS03445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS03445	COG1263	PTS System
EXW31_RS03450	COG0366	Alpha amylase catalytic
EXW31_RS03470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW31_RS03475	COG1115	amino acid carrier protein
EXW31_RS03480	COG1126	abc transporter atp-binding protein
EXW31_RS03485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS03490	COG0765	amino acid transport
EXW31_RS03495	COG0765	amino acid transport
EXW31_RS03500	COG0833	amino acid
EXW31_RS03525	COG2378	regulation of single-species biofilm formation
EXW31_RS03530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW31_RS03535	COG5002	protein histidine kinase activity
EXW31_RS03550	COG0659	secondary active sulfate transmembrane transporter activity
EXW31_RS03575	COG0601	transmembrane transport
EXW31_RS03580	COG4608	Belongs to the ABC transporter superfamily
EXW31_RS03590	COG2271	Major facilitator Superfamily
EXW31_RS03595	COG1846	Transcriptional regulator
EXW31_RS03600	COG0477	Major facilitator Superfamily
EXW31_RS03605	COG1609	Transcriptional regulator
EXW31_RS03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW31_RS03615	COG1869	D-ribose catabolic process
EXW31_RS03625	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW31_RS03630	COG1879	ABC-type sugar transport system periplasmic component
EXW31_RS03660	COG1063	alcohol dehydrogenase
EXW31_RS03705	COG0840	transmembrane signaling receptor activity
EXW31_RS03710	COG3583	domain protein
EXW31_RS03710	COG3584	3D domain protein
EXW31_RS03715	COG1476	TRANSCRIPTIONal
EXW31_RS03735	COG3104	oligopeptide transport
EXW31_RS03740	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS03755	COG1113	amino acid transport
EXW31_RS03760	COG2252	PERMEase
EXW31_RS03775	COG2153	protein acetylation
EXW31_RS03785	COG0475	glutathione-regulated potassium exporter activity
EXW31_RS03785	COG0569	domain protein
EXW31_RS03795	COG1845	cytochrome c oxidase, subunit III
EXW31_RS03800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW31_RS03805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW31_RS03810	COG0833	amino acid
EXW31_RS03815	COG4990	cell redox homeostasis
EXW31_RS03830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW31_RS03835	COG0697	spore germination
EXW31_RS03840	COG0531	amino acid
EXW31_RS03855	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW31_RS03860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW31_RS03870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW31_RS03875	COG0573	inorganic phosphate transmembrane transporter activity
EXW31_RS03880	COG0581	inorganic phosphate transmembrane transporter activity
EXW31_RS03890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW31_RS03935	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW31_RS04015	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW31_RS04030	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS04030	COG3103	Sh3 type 3 domain protein
EXW31_RS04030	COG4991	sh3 domain protein
EXW31_RS04035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW31_RS04040	COG1116	anion transmembrane transporter activity
EXW31_RS04045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW31_RS04050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW31_RS04055	COG0352	thiamine-phosphate diphosphorylase activity
EXW31_RS04060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW31_RS04065	COG2104	thiamine diphosphate biosynthetic process
EXW31_RS04070	COG2022	thiamine diphosphate biosynthetic process
EXW31_RS04075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW31_RS04080	COG0351	phosphomethylpyrimidine kinase
EXW31_RS04110	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW31_RS04115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW31_RS04120	COG2205	protein histidine kinase activity
EXW31_RS04145	COG1136	(ABC) transporter
EXW31_RS04155	COG2252	PERMEase
EXW31_RS04160	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS04220	COG0778	Nitroreductase
EXW31_RS04225	COG2719	SpoVR family
EXW31_RS04250	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW31_RS04260	COG1937	Protein conserved in bacteria
EXW31_RS04265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW31_RS04265	COG0425	Belongs to the sulfur carrier protein TusA family
EXW31_RS04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW31_RS04270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS04275	COG0425	Belongs to the sulfur carrier protein TusA family
EXW31_RS04280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW31_RS04285	COG2210	Belongs to the sulfur carrier protein TusA family
EXW31_RS04290	COG0730	response to heat
EXW31_RS04300	COG1316	TRANSCRIPTIONal
EXW31_RS04305	COG0604	alcohol dehydrogenase
EXW31_RS04310	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW31_RS04320	COG2814	Major facilitator Superfamily
EXW31_RS04330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW31_RS04330	COG3711	transcriptional antiterminator
EXW31_RS04335	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW31_RS04340	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS04360	COG1388	LysM domain
EXW31_RS04360	COG3584	3D domain protein
EXW31_RS04365	COG0577	efflux transmembrane transporter activity
EXW31_RS04370	COG1136	(ABC) transporter
EXW31_RS04380	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW31_RS04395	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS04400	COG3546	catalase activity
EXW31_RS04430	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS04460	COG0531	amino acid
EXW31_RS04465	COG0475	glutathione-regulated potassium exporter activity
EXW31_RS04485	COG1263	PTS System
EXW31_RS04485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS04495	COG2259	Doxx family
EXW31_RS04520	COG1522	sequence-specific DNA binding
EXW31_RS04530	COG0300	oxidoreductase activity
EXW31_RS04545	COG2076	Multidrug Resistance protein
EXW31_RS04550	COG1309	transcriptional regulator
EXW31_RS04555	COG2814	Major facilitator Superfamily
EXW31_RS04560	COG1733	regulation of RNA biosynthetic process
EXW31_RS04570	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS04595	COG4473	ABC transporter
EXW31_RS04600	COG0531	amino acid
EXW31_RS04610	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS04615	COG1132	(ABC) transporter
EXW31_RS04620	COG1132	(ABC) transporter
EXW31_RS04625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS04630	COG0765	amino acid transport
EXW31_RS04635	COG1126	abc transporter atp-binding protein
EXW31_RS04650	COG0189	ligase activity
EXW31_RS04660	COG4399	Belongs to the UPF0754 family
EXW31_RS04665	COG3679	Belongs to the UPF0342 family
EXW31_RS04680	COG0028	Belongs to the TPP enzyme family
EXW31_RS04685	COG3527	Alpha-acetolactate decarboxylase
EXW31_RS04690	COG0463	Glycosyl transferase, family 2
EXW31_RS04695	COG1216	Glycosyl transferase, family 2
EXW31_RS04700	COG2094	Belongs to the DNA glycosylase MPG family
EXW31_RS04705	COG0561	phosphatase activity
EXW31_RS04715	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS04715	COG3409	Peptidoglycan-binding domain 1 protein
EXW31_RS04720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW31_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS04735	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS04745	COG0789	Transcriptional regulator
EXW31_RS04745	COG4978	Transcriptional regulator
EXW31_RS04755	COG0659	secondary active sulfate transmembrane transporter activity
EXW31_RS04760	COG2244	polysaccharide biosynthetic process
EXW31_RS04780	COG1024	Enoyl-CoA hydratase
EXW31_RS04800	COG1363	Peptidase, m42
EXW31_RS04820	COG2318	DinB family
EXW31_RS04830	COG1113	amino acid transport
EXW31_RS04835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS04855	COG0579	oxidoreductase
EXW31_RS04865	COG3290	protein histidine kinase activity
EXW31_RS04865	COG3829	transcription factor binding
EXW31_RS04875	COG1301	dicarboxylic acid transport
EXW31_RS04945	COG3181	Tripartite tricarboxylate transporter family receptor
EXW31_RS04980	COG0305	Participates in initiation and elongation during chromosome replication
EXW31_RS05005	COG1842	Phage shock protein A
EXW31_RS05015	COG0477	Major facilitator Superfamily
EXW31_RS05065	COG1183	phosphatidylcholine synthase activity
EXW31_RS05080	COG2814	Major facilitator Superfamily
EXW31_RS05085	COG0640	Transcriptional regulator
EXW31_RS05110	COG2376	Dihydroxyacetone kinase
EXW31_RS05130	COG2376	Dihydroxyacetone kinase
EXW31_RS05155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW31_RS05155	COG2755	lipolytic protein G-D-S-L family
EXW31_RS05170	COG2720	vancomycin resistance protein
EXW31_RS05175	COG1335	isochorismatase
EXW31_RS05190	COG2373	Large extracellular alpha-helical protein
EXW31_RS05230	COG0076	glutamate decarboxylase activity
EXW31_RS05240	COG5658	integral membrane protein
EXW31_RS05255	COG1595	DNA-templated transcription, initiation
EXW31_RS05290	COG2807	transmembrane transport
EXW31_RS05295	COG2186	Transcriptional regulator
EXW31_RS05310	COG4585	Histidine kinase
EXW31_RS05315	COG2197	response regulator
EXW31_RS05340	COG0420	3'-5' exonuclease activity
EXW31_RS05345	COG4717	serine-type aminopeptidase activity
EXW31_RS05350	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW31_RS05360	COG0346	lactoylglutathione lyase activity
EXW31_RS05365	COG2267	carboxylic ester hydrolase activity
EXW31_RS05375	COG2140	Oxalate decarboxylase
EXW31_RS05380	COG3620	sequence-specific DNA binding
EXW31_RS05385	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW31_RS05390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW31_RS05395	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW31_RS05400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW31_RS05415	COG0693	protein deglycase activity
EXW31_RS05420	COG1595	DNA-templated transcription, initiation
EXW31_RS05435	COG3973	AAA domain
EXW31_RS05465	COG0537	adenosine 5'-monophosphoramidase activity
EXW31_RS05470	COG1131	(ABC) transporter
EXW31_RS05475	COG4473	ABC transporter
EXW31_RS05505	COG0247	lactate metabolic process
EXW31_RS05510	COG1139	Iron-sulfur cluster binding protein
EXW31_RS05515	COG1556	Lactate utilization protein
EXW31_RS05550	COG1309	transcriptional regulator
EXW31_RS05560	COG3402	PFAM membrane-flanked domain
EXW31_RS05565	COG3428	Bacterial PH domain
EXW31_RS05590	COG3402	PFAM membrane-flanked domain
EXW31_RS05595	COG3428	Bacterial PH domain
EXW31_RS05600	COG2329	Antibiotic biosynthesis monooxygenase
EXW31_RS05605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW31_RS05610	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW31_RS05615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW31_RS05620	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW31_RS05660	COG1309	transcriptional regulator
EXW31_RS05665	COG1511	domain protein
EXW31_RS05670	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS05670	COG1216	Glycosyl transferase, family 2
EXW31_RS05690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS05700	COG2378	regulation of single-species biofilm formation
EXW31_RS05705	COG1609	Transcriptional regulator
EXW31_RS05715	COG1234	tRNA 3'-trailer cleavage
EXW31_RS05720	COG0095	Lipoate-protein ligase
EXW31_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS05755	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW31_RS05760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW31_RS05765	COG4208	sulfate ABC transporter
EXW31_RS05775	COG1408	metallophosphoesterase
EXW31_RS05780	COG1078	dGTPase activity
EXW31_RS05805	COG1595	DNA-templated transcription, initiation
EXW31_RS05810	COG2207	Transcriptional regulator
EXW31_RS05810	COG3708	Transcriptional regulator
EXW31_RS05815	COG2205	protein histidine kinase activity
EXW31_RS05820	COG0745	RESPONSE REGULATOR receiver
EXW31_RS05845	COG0501	Belongs to the peptidase M48B family
EXW31_RS05850	COG0697	spore germination
EXW31_RS05860	COG2373	Large extracellular alpha-helical protein
EXW31_RS05865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW31_RS05870	COG2224	Isocitrate lyase
EXW31_RS05880	COG1278	Cold shock
EXW31_RS05890	COG4903	ComK protein
EXW31_RS05895	COG0398	Pfam SNARE associated Golgi protein
EXW31_RS05925	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW31_RS05930	COG1074	ATP-dependent DNA helicase activity
EXW31_RS05980	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW31_RS06005	COG0367	asparagine synthase
EXW31_RS06015	COG0753	catalase activity
EXW31_RS06020	COG0004	ammonium transporteR
EXW31_RS06035	COG1666	GTP binding
EXW31_RS06040	COG2996	Protein conserved in bacteria
EXW31_RS06055	COG1329	Transcriptional regulator
EXW31_RS06085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW31_RS06095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS06110	COG0561	phosphatase activity
EXW31_RS06130	COG2267	carboxylic ester hydrolase activity
EXW31_RS06145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW31_RS06150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW31_RS06155	COG5504	Zn-dependent protease
EXW31_RS06165	COG0180	Tryptophanyl-tRNA synthetase
EXW31_RS06175	COG4166	transmembrane transport
EXW31_RS06180	COG0601	transmembrane transport
EXW31_RS06185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW31_RS06190	COG0444	Belongs to the ABC transporter superfamily
EXW31_RS06195	COG4608	Belongs to the ABC transporter superfamily
EXW31_RS06200	COG0534	Mate efflux family protein
EXW31_RS06205	COG4166	transmembrane transport
EXW31_RS06220	COG0861	Integral membrane protein TerC family
EXW31_RS06225	COG4862	establishment of competence for transformation
EXW31_RS06230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW31_RS06240	COG1164	Oligoendopeptidase f
EXW31_RS06255	COG2346	COG2346, Truncated hemoglobins
EXW31_RS06260	COG4116	CYTH
EXW31_RS06270	COG2357	RelA SpoT domain protein
EXW31_RS06280	COG0564	pseudouridine synthase activity
EXW31_RS06290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW31_RS06295	COG0772	Belongs to the SEDS family
EXW31_RS06305	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW31_RS06320	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW31_RS06365	COG2153	protein acetylation
EXW31_RS06370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW31_RS06375	COG2382	esterase
EXW31_RS06400	COG5492	domain, Protein
EXW31_RS06405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW31_RS06415	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW31_RS06415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW31_RS06420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW31_RS06425	COG0134	indole-3-glycerol-phosphate synthase activity
EXW31_RS06430	COG0135	phosphoribosylanthranilate isomerase activity
EXW31_RS06440	COG0159	tryptophan synthase activity
EXW31_RS06450	COG1620	l-lactate permease
EXW31_RS06455	COG5634	Uncharacterized conserved protein (DUF2278)
EXW31_RS06505	COG2226	methyltransferase
EXW31_RS06525	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW31_RS06530	COG0567	Dehydrogenase, E1 component
EXW31_RS06535	COG1476	TRANSCRIPTIONal
EXW31_RS06580	COG1686	Belongs to the peptidase S11 family
EXW31_RS06585	COG0681	Belongs to the peptidase S26 family
EXW31_RS06620	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS06630	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW31_RS06635	COG1177	transmembrane transport
EXW31_RS06640	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW31_RS06650	COG2409	Drug exporters of the RND superfamily
EXW31_RS06660	COG0564	pseudouridine synthase activity
EXW31_RS06670	COG2340	Cysteine-rich secretory protein family
EXW31_RS06675	COG0247	lactate metabolic process
EXW31_RS06680	COG0277	FAD linked oxidase domain protein
EXW31_RS06685	COG3835	regulator
EXW31_RS06695	COG0745	RESPONSE REGULATOR receiver
EXW31_RS06700	COG5002	protein histidine kinase activity
EXW31_RS06700	COG3850	Histidine kinase
EXW31_RS06705	COG2186	Transcriptional regulator
EXW31_RS06720	COG1556	Lactate utilization protein
EXW31_RS06725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW31_RS06740	COG2116	formate transmembrane transporter activity
EXW31_RS06745	COG0861	Integral membrane protein TerC family
EXW31_RS06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW31_RS06760	COG2030	dehydratase
EXW31_RS06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW31_RS06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW31_RS06810	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW31_RS06815	COG3842	ATPase activity
EXW31_RS06825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW31_RS06830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW31_RS06840	COG1349	DNA-binding transcription factor activity
EXW31_RS06850	COG0235	Class ii aldolase
EXW31_RS06860	COG2861	carbohydrate metabolic process
EXW31_RS06870	COG3852	Histidine kinase
EXW31_RS06875	COG1846	Transcriptional regulator
EXW31_RS06885	COG2318	DinB family
EXW31_RS06890	COG5002	protein histidine kinase activity
EXW31_RS06900	COG0720	synthase
EXW31_RS06910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW31_RS06915	COG4873	Protein conserved in bacteria
EXW31_RS06930	COG0456	acetyltransferase
EXW31_RS06945	COG1780	Probably involved in ribonucleotide reductase function
EXW31_RS06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW31_RS06965	COG0531	amino acid
EXW31_RS06980	COG2204	response regulator
EXW31_RS06985	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS06995	COG1725	Transcriptional regulator
EXW31_RS07000	COG1131	(ABC) transporter
EXW31_RS07010	COG1131	(ABC) transporter
EXW31_RS07015	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW31_RS07020	COG1266	CAAX protease self-immunity
EXW31_RS07030	COG1522	sequence-specific DNA binding
EXW31_RS07040	COG1335	isochorismatase
EXW31_RS07050	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW31_RS07055	COG2070	2-Nitropropane dioxygenase
EXW31_RS07060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW31_RS07065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW31_RS07070	COG1696	Membrane protein involved in D-alanine export
EXW31_RS07095	COG0716	FMN binding
EXW31_RS07110	COG3173	Aminoglycoside phosphotransferase
EXW31_RS07130	COG0534	Mate efflux family protein
EXW31_RS07150	COG1846	Transcriptional regulator
EXW31_RS07165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW31_RS07175	COG3874	Sporulation protein YtfJ
EXW31_RS07195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS07200	COG0028	Belongs to the TPP enzyme family
EXW31_RS07205	COG0440	acetolactate synthase activity
EXW31_RS07215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW31_RS07225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW31_RS07235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW31_RS07240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW31_RS07250	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW31_RS07255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW31_RS07260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW31_RS07265	COG0107	imidazoleglycerol-phosphate synthase activity
EXW31_RS07275	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW31_RS07280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW31_RS07295	COG1183	phosphatidylcholine synthase activity
EXW31_RS07300	COG1368	sulfuric ester hydrolase activity
EXW31_RS07310	COG0019	diaminopimelate decarboxylase activity
EXW31_RS07325	COG2046	Belongs to the sulfate adenylyltransferase family
EXW31_RS07330	COG0529	Catalyzes the synthesis of activated sulfate
EXW31_RS07335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW31_RS07355	COG1648	precorrin-2 dehydrogenase activity
EXW31_RS07360	COG0733	neurotransmitter:sodium symporter activity
EXW31_RS07385	COG1757	Na H antiporter
EXW31_RS07400	COG4758	membrane
EXW31_RS07405	COG4585	Histidine kinase
EXW31_RS07410	COG2197	response regulator
EXW31_RS07420	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS07430	COG2226	methyltransferase
EXW31_RS07470	COG0730	response to heat
EXW31_RS07475	COG0306	phosphate transporter
EXW31_RS07480	COG1392	Phosphate transport regulator
EXW31_RS07485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW31_RS07500	COG3852	Histidine kinase
EXW31_RS07505	COG1801	Protein of unknown function DUF72
EXW31_RS07520	COG0582	viral genome integration into host DNA
EXW31_RS07525	COG5002	protein histidine kinase activity
EXW31_RS07540	COG0392	lysyltransferase activity
EXW31_RS07540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW31_RS07555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW31_RS07560	COG1686	Belongs to the peptidase S11 family
EXW31_RS07565	COG2715	membrane protein required for spore maturation
EXW31_RS07570	COG0700	Nucleoside recognition
EXW31_RS07575	COG1187	pseudouridine synthase activity
EXW31_RS07585	COG1333	cytochrome c biogenesis protein
EXW31_RS07590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW31_RS07595	COG0745	RESPONSE REGULATOR receiver
EXW31_RS07600	COG5002	protein histidine kinase activity
EXW31_RS07605	COG2096	Adenosyltransferase
EXW31_RS07610	COG4942	peptidase
EXW31_RS07620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW31_RS07625	COG1141	Ferredoxin
EXW31_RS07630	COG4955	Helix-turn-helix domain
EXW31_RS07635	COG0514	ATP-dependent DNA helicase (RecQ)
EXW31_RS07640	COG1266	CAAX protease self-immunity
EXW31_RS07650	COG1408	metallophosphoesterase
EXW31_RS07665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW31_RS07680	COG0492	ferredoxin-NADP+ reductase activity
EXW31_RS07685	COG0252	asparaginase activity
EXW31_RS07695	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW31_RS07705	COG1304	FMN binding
EXW31_RS07735	COG1160	GTP binding
EXW31_RS07740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW31_RS07760	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW31_RS07775	COG0142	geranyltranstransferase activity
EXW31_RS07780	COG2226	methyltransferase
EXW31_RS07785	COG0142	geranyltranstransferase activity
EXW31_RS07800	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW31_RS07810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW31_RS07815	COG0457	Tetratricopeptide repeat
EXW31_RS07820	COG5582	Belongs to the UPF0302 family
EXW31_RS07835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW31_RS07840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW31_RS07840	COG2010	Cytochrome c
EXW31_RS07845	COG4347	Protein of unknown function (DUF1405)
EXW31_RS07860	COG2738	Putative neutral zinc metallopeptidase
EXW31_RS07870	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS07875	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW31_RS07880	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW31_RS07885	COG1803	Methylglyoxal synthase
EXW31_RS07890	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW31_RS07895	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS07900	COG0617	tRNA 3'-terminal CCA addition
EXW31_RS07910	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW31_RS07915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW31_RS07925	COG1199	ATP-dependent helicase activity
EXW31_RS07925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW31_RS07945	COG3935	DnaD domain protein
EXW31_RS07950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW31_RS07960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW31_RS07960	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW31_RS07965	COG3331	DNA recombination
EXW31_RS08000	COG4474	Belongs to the UPF0398 family
EXW31_RS08005	COG3599	regulation of cell shape
EXW31_RS08015	COG0116	Belongs to the methyltransferase superfamily
EXW31_RS08025	COG1199	ATP-dependent helicase activity
EXW31_RS08030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW31_RS08040	COG0024	Methionine aminopeptidase
EXW31_RS08050	COG2233	PERMEase
EXW31_RS08055	COG2311	Membrane
EXW31_RS08060	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW31_RS08070	COG0456	acetyltransferase
EXW31_RS08080	COG2897	thiosulfate sulfurtransferase activity
EXW31_RS08120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW31_RS08160	COG0328	RNA-DNA hybrid ribonuclease activity
EXW31_RS08205	COG3403	YqcI/YcgG family
EXW31_RS08210	COG1280	lysine exporter protein (LysE YggA)
EXW31_RS08225	COG3162	membrane
EXW31_RS08230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW31_RS08235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW31_RS08245	COG0475	glutathione-regulated potassium exporter activity
EXW31_RS08250	COG0789	Transcriptional regulator
EXW31_RS08250	COG4978	Transcriptional regulator
EXW31_RS08255	COG0534	Mate efflux family protein
EXW31_RS08260	COG2323	membrane
EXW31_RS08265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW31_RS08285	COG1609	Transcriptional regulator
EXW31_RS08295	COG1175	transmembrane transport
EXW31_RS08300	COG0395	ABC-type sugar transport system, permease component
EXW31_RS08305	COG5578	integral membrane protein
EXW31_RS08315	COG1486	melibiose metabolic process
EXW31_RS08330	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EXW31_RS08335	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW31_RS08340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW31_RS08375	COG1923	regulation of RNA biosynthetic process
EXW31_RS08385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW31_RS08390	COG1360	Flagellar Motor Protein
EXW31_RS08395	COG2201	protein-glutamate methylesterase activity
EXW31_RS08400	COG0643	Histidine kinase
EXW31_RS08400	COG2198	Histidine kinase
EXW31_RS08405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW31_RS08405	COG1776	CheC inhibitor of MCP methylation
EXW31_RS08420	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW31_RS08440	COG1256	bacterial-type flagellum assembly
EXW31_RS08450	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EXW31_RS08465	COG1815	bacterial-type flagellum-dependent cell motility
EXW31_RS08470	COG1558	bacterial-type flagellum-dependent cell motility
EXW31_RS08480	COG1766	The M ring may be actively involved in energy transduction
EXW31_RS08485	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW31_RS08495	COG1157	protein secretion by the type III secretion system
EXW31_RS08515	COG1749	Flagellar hook protein flgE
EXW31_RS08530	COG0835	chemotaxis
EXW31_RS08530	COG0784	Response regulator, receiver
EXW31_RS08540	COG0861	Integral membrane protein TerC family
EXW31_RS08550	COG3383	formate dehydrogenase (NAD+) activity
EXW31_RS08555	COG2427	Protein of unknown function (DUF1641)
EXW31_RS08560	COG5609	conserved protein (DUF2294)
EXW31_RS08565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW31_RS08575	COG2116	formate transmembrane transporter activity
EXW31_RS08580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW31_RS08585	COG0303	'Molybdopterin
EXW31_RS08590	COG0314	molybdopterin synthase activity
EXW31_RS08595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW31_RS08605	COG0489	protein tyrosine kinase activity
EXW31_RS08615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW31_RS08620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW31_RS08625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW31_RS08630	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW31_RS08635	COG0741	lytic transglycosylase activity
EXW31_RS08645	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW31_RS08650	COG1776	CheC inhibitor of MCP methylation
EXW31_RS08650	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW31_RS08660	COG1338	Plays a role in the flagellum-specific transport system
EXW31_RS08665	COG1987	bacterial-type flagellum assembly
EXW31_RS08675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW31_RS08680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW31_RS08685	COG1419	protein localization to endoplasmic reticulum
EXW31_RS08690	COG4787	bacterial-type flagellum-dependent cell motility
EXW31_RS08725	COG1309	transcriptional regulator
EXW31_RS08740	COG0412	Dienelactone hydrolase
EXW31_RS08745	COG2329	Antibiotic biosynthesis monooxygenase
EXW31_RS08760	COG3764	Sortase (surface protein transpeptidase)
EXW31_RS08765	COG3764	Sortase (surface protein transpeptidase)
EXW31_RS08790	COG0583	DNA-binding transcription factor activity
EXW31_RS08795	COG3842	ATPase activity
EXW31_RS08800	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW31_RS08855	COG1846	Transcriptional regulator
EXW31_RS08865	COG0367	asparagine synthase
EXW31_RS08895	COG1757	Na H antiporter
EXW31_RS08905	COG0277	FAD linked oxidase domain protein
EXW31_RS08925	COG0534	Mate efflux family protein
EXW31_RS08930	COG3340	Belongs to the peptidase S51 family
EXW31_RS08950	COG0785	Cytochrome C biogenesis protein
EXW31_RS08970	COG3048	D-serine ammonia-lyase activity
EXW31_RS08975	COG2733	membrane
EXW31_RS09010	COG1131	(ABC) transporter
EXW31_RS09030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW31_RS09035	COG0528	UMP kinase activity
EXW31_RS09045	COG1027	Aspartate ammonia-lyase
EXW31_RS09050	COG0281	malic enzyme
EXW31_RS09055	COG4191	Histidine kinase
EXW31_RS09060	COG0784	Response regulator, receiver
EXW31_RS09065	COG1846	Transcriptional regulator
EXW31_RS09075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW31_RS09085	COG2502	aspartate--ammonia ligase
EXW31_RS09090	COG3620	sequence-specific DNA binding
EXW31_RS09130	COG1695	Transcriptional regulator
EXW31_RS09145	COG0477	Major facilitator Superfamily
EXW31_RS09155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW31_RS09165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW31_RS09170	COG4166	transmembrane transport
EXW31_RS09175	COG2223	nitrite transmembrane transporter activity
EXW31_RS09180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW31_RS09195	COG2244	polysaccharide biosynthetic process
EXW31_RS09200	COG0733	neurotransmitter:sodium symporter activity
EXW31_RS09210	COG5566	PFAM Mor transcription activator
EXW31_RS09215	COG2323	membrane
EXW31_RS09230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW31_RS09245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW31_RS09270	COG2814	Major facilitator Superfamily
EXW31_RS09275	COG3384	dioxygenase
EXW31_RS09310	COG4166	transmembrane transport
EXW31_RS09340	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS09350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS09360	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW31_RS09365	COG1054	Belongs to the UPF0176 family
EXW31_RS09375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW31_RS09380	COG0531	amino acid
EXW31_RS09400	COG1280	lysine exporter protein (LysE YggA)
EXW31_RS09415	COG2390	Transcriptional regulator
EXW31_RS09420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW31_RS09425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS09430	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW31_RS09445	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW31_RS09470	COG2267	carboxylic ester hydrolase activity
EXW31_RS09475	COG0583	DNA-binding transcription factor activity
EXW31_RS09495	COG0006	proline dipeptidase activity
EXW31_RS09505	COG2132	Multicopper oxidase
EXW31_RS09515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW31_RS09525	COG0583	DNA-binding transcription factor activity
EXW31_RS09545	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS09555	COG1276	copper resistance
EXW31_RS09555	COG2372	response to copper ion
EXW31_RS09560	COG4549	nuclear export factor GLE1
EXW31_RS09570	COG0697	spore germination
EXW31_RS09575	COG0583	DNA-binding transcription factor activity
EXW31_RS09580	COG1959	2 iron, 2 sulfur cluster binding
EXW31_RS09585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW31_RS09600	COG0628	permease
EXW31_RS09615	COG1231	oxidoreductase activity
EXW31_RS09620	COG0523	cobalamin synthesis protein
EXW31_RS09630	COG0411	ABC transporter
EXW31_RS09650	COG0583	DNA-binding transcription factor activity
EXW31_RS09660	COG1942	4-Oxalocrotonate Tautomerase
EXW31_RS09675	COG0346	lactoylglutathione lyase activity
EXW31_RS09685	COG1271	oxidase subunit
EXW31_RS09690	COG1294	oxidase, subunit
EXW31_RS09695	COG4988	ABC transporter
EXW31_RS09700	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW31_RS09725	COG1686	Belongs to the peptidase S11 family
EXW31_RS09740	COG0791	NLP P60 protein
EXW31_RS09740	COG1388	LysM domain
EXW31_RS09750	COG1132	(ABC) transporter
EXW31_RS09755	COG0745	RESPONSE REGULATOR receiver
EXW31_RS09760	COG5002	protein histidine kinase activity
EXW31_RS09765	COG0300	oxidoreductase activity
EXW31_RS09770	COG4122	O-methyltransferase activity
EXW31_RS09800	COG0460	homoserine dehydrogenase
EXW31_RS09810	COG0083	homoserine kinase activity
EXW31_RS09825	COG1316	TRANSCRIPTIONal
EXW31_RS09840	COG1285	pathogenesis
EXW31_RS09865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW31_RS09875	COG1082	Xylose isomerase domain protein TIM barrel
EXW31_RS09885	COG2814	Major facilitator Superfamily
EXW31_RS09890	COG1279	arginine transmembrane transporter activity
EXW31_RS09895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS09905	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW31_RS09945	COG0577	efflux transmembrane transporter activity
EXW31_RS09950	COG2002	toxin-antitoxin pair type II binding
EXW31_RS09955	COG1404	Belongs to the peptidase S8 family
EXW31_RS09965	COG3842	ATPase activity
EXW31_RS09970	COG2508	Transcriptional regulator
EXW31_RS09980	COG1653	transport
EXW31_RS09985	COG1175	transmembrane transport
EXW31_RS09990	COG0395	ABC-type sugar transport system, permease component
EXW31_RS09995	COG5426	von Willebrand factor, type A
EXW31_RS10005	COG1940	carbohydrate kinase activity
EXW31_RS10010	COG2222	sugar isomerase
EXW31_RS10020	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW31_RS10025	COG3684	Belongs to the aldolase LacD family
EXW31_RS10030	COG0366	Alpha amylase catalytic
EXW31_RS10035	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW31_RS10080	COG3949	Membrane
EXW31_RS10085	COG0783	Belongs to the Dps family
EXW31_RS10100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW31_RS10110	COG1231	oxidoreductase activity
EXW31_RS10115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS10120	COG4989	oxidoreductase activity
EXW31_RS10125	COG0523	cobalamin synthesis protein
EXW31_RS10130	COG0456	acetyltransferase
EXW31_RS10135	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW31_RS10145	COG0702	epimerase
EXW31_RS10155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW31_RS10165	COG4166	transmembrane transport
EXW31_RS10170	COG0346	lactoylglutathione lyase activity
EXW31_RS10180	COG0406	alpha-ribazole phosphatase activity
EXW31_RS10190	COG5337	Spore coat protein CotH
EXW31_RS10195	COG1051	belongs to the nudix hydrolase family
EXW31_RS10200	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS10205	COG2244	polysaccharide biosynthetic process
EXW31_RS10215	COG0701	Predicted permease
EXW31_RS10220	COG3689	TIGRFAM TIGR03943 family protein
EXW31_RS10225	COG1607	acyl-coa hydrolase
EXW31_RS10235	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW31_RS10250	COG0702	epimerase
EXW31_RS10255	COG2839	Protein conserved in bacteria
EXW31_RS10260	COG1253	flavin adenine dinucleotide binding
EXW31_RS10275	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS10280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW31_RS10295	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS10305	COG1876	peptidase activity
EXW31_RS10320	COG2211	Major facilitator Superfamily
EXW31_RS10410	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS10420	COG0561	phosphatase activity
EXW31_RS10430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW31_RS10450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS10455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS10480	COG0456	acetyltransferase
EXW31_RS10550	COG4974	Belongs to the 'phage' integrase family
EXW31_RS10580	COG0582	viral genome integration into host DNA
EXW31_RS10630	COG3874	Sporulation protein YtfJ
EXW31_RS10655	COG2226	methyltransferase
EXW31_RS10675	COG0346	lactoylglutathione lyase activity
EXW31_RS10685	COG0604	alcohol dehydrogenase
EXW31_RS10690	COG1595	DNA-templated transcription, initiation
EXW31_RS10715	COG0426	domain, Protein
EXW31_RS10715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW31_RS10725	COG0386	Belongs to the glutathione peroxidase family
EXW31_RS10730	COG1305	Transglutaminase-like
EXW31_RS10735	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW31_RS10740	COG0714	Associated with various cellular activities
EXW31_RS10755	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW31_RS10760	COG1140	nitrate reductase beta subunit
EXW31_RS10765	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW31_RS10770	COG2181	nitrate reductase activity
EXW31_RS10775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW31_RS10780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW31_RS10785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW31_RS10790	COG0303	'Molybdopterin
EXW31_RS10795	COG0314	molybdopterin synthase activity
EXW31_RS10805	COG2223	nitrite transmembrane transporter activity
EXW31_RS10810	COG1648	precorrin-2 dehydrogenase activity
EXW31_RS10820	COG1587	Uroporphyrinogen-III synthase
EXW31_RS10820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW31_RS10825	COG2146	nitrite reductase [NAD(P)H] activity
EXW31_RS10830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW31_RS10835	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW31_RS10860	COG2359	stage V sporulation protein S
EXW31_RS10870	COG1418	mRNA catabolic process
EXW31_RS10875	COG0488	(ABC) transporter
EXW31_RS10895	COG1413	lyase activity
EXW31_RS10910	COG2521	methyltransferase
EXW31_RS10910	COG2136	Putative SAM-dependent methyltransferase
EXW31_RS10915	COG0018	arginyl-trna synthetase
EXW31_RS10960	COG0017	Asparaginyl-tRNA synthetase
EXW31_RS10980	COG1674	ftsk spoiiie
EXW31_RS11030	COG0733	neurotransmitter:sodium symporter activity
EXW31_RS11055	COG2610	gluconate transmembrane transporter activity
EXW31_RS11060	COG1454	alcohol dehydrogenase
EXW31_RS11070	COG0456	acetyltransferase
EXW31_RS11075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW31_RS11080	COG1131	(ABC) transporter
EXW31_RS11085	COG4473	ABC transporter
EXW31_RS11095	COG0546	phosphoglycolate phosphatase activity
EXW31_RS11120	COG0671	phosphoesterase, PA-phosphatase related
EXW31_RS11140	COG0768	penicillin binding
EXW31_RS11150	COG0204	Acyl-transferase
EXW31_RS11155	COG1272	protein, Hemolysin III
EXW31_RS11160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW31_RS11165	COG0805	protein transport
EXW31_RS11175	COG1307	EDD domain protein, DegV family
EXW31_RS11180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW31_RS11185	COG1999	signal sequence binding
EXW31_RS11190	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW31_RS11195	COG0367	asparagine synthase
EXW31_RS11205	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW31_RS11210	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS11215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS11230	COG1335	isochorismatase
EXW31_RS11240	COG0668	transmembrane transport
EXW31_RS11245	COG2203	Gaf domain
EXW31_RS11245	COG4585	Histidine kinase
EXW31_RS11250	COG2197	response regulator
EXW31_RS11255	COG1737	Transcriptional regulator
EXW31_RS11260	COG1064	alcohol dehydrogenase
EXW31_RS11280	COG1070	Carbohydrate kinase
EXW31_RS11290	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW31_RS11310	COG0517	IMP dehydrogenase activity
EXW31_RS11310	COG1125	glycine betaine transport
EXW31_RS11315	COG1174	glycine betaine transport
EXW31_RS11350	COG1253	flavin adenine dinucleotide binding
EXW31_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS11360	COG5506	Protein of unknown function (DUF1694)
EXW31_RS11375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW31_RS11380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW31_RS11385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW31_RS11390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW31_RS11395	COG0456	acetyltransferase
EXW31_RS11400	COG3829	transcription factor binding
EXW31_RS11405	COG1509	lysine 2,3-aminomutase activity
EXW31_RS11415	COG4479	Belongs to the UPF0346 family
EXW31_RS11440	COG4991	sh3 domain protein
EXW31_RS11440	COG3064	Membrane
EXW31_RS11440	COG0515	serine threonine protein kinase
EXW31_RS11450	COG0671	phosphoesterase, PA-phosphatase related
EXW31_RS11455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW31_RS11460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW31_RS11465	COG0582	viral genome integration into host DNA
EXW31_RS11525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW31_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS11575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW31_RS11575	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW31_RS11585	COG2814	Major facilitator Superfamily
EXW31_RS11595	COG0372	Belongs to the citrate synthase family
EXW31_RS11600	COG2079	MmgE PrpD family protein
EXW31_RS11605	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW31_RS11610	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS11615	COG2084	Dehydrogenase
EXW31_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS11625	COG1280	lysine exporter protein (LysE YggA)
EXW31_RS11630	COG1024	Enoyl-CoA hydratase
EXW31_RS11645	COG0420	3'-5' exonuclease activity
EXW31_RS11650	COG0419	ATPase involved in DNA repair
EXW31_RS11670	COG2223	nitrite transmembrane transporter activity
EXW31_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS11680	COG1169	isochorismate synthase
EXW31_RS11685	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW31_RS11690	COG1535	isochorismatase
EXW31_RS11690	COG3433	isochorismatase activity
EXW31_RS11695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW31_RS11700	COG3251	PFAM MbtH domain protein
EXW31_RS11705	COG2814	Major facilitator Superfamily
EXW31_RS11720	COG0776	regulation of translation
EXW31_RS11730	COG1115	amino acid carrier protein
EXW31_RS11745	COG2329	Antibiotic biosynthesis monooxygenase
EXW31_RS11755	COG1187	pseudouridine synthase activity
EXW31_RS11760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW31_RS11785	COG1136	(ABC) transporter
EXW31_RS11795	COG0596	Alpha beta hydrolase
EXW31_RS11810	COG0028	Belongs to the TPP enzyme family
EXW31_RS11840	COG1253	flavin adenine dinucleotide binding
EXW31_RS11885	COG1846	Transcriptional regulator
EXW31_RS11895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS11900	COG1309	transcriptional regulator
EXW31_RS11910	COG0697	spore germination
EXW31_RS11915	COG0531	amino acid
EXW31_RS11930	COG1247	-acetyltransferase
EXW31_RS11965	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW31_RS11980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS12005	COG0561	phosphatase activity
EXW31_RS12015	COG0583	DNA-binding transcription factor activity
EXW31_RS12020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW31_RS12055	COG0583	DNA-binding transcription factor activity
EXW31_RS12060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW31_RS12065	COG2258	MOSC domain
EXW31_RS12080	COG1132	(ABC) transporter
EXW31_RS12085	COG1132	(ABC) transporter
EXW31_RS12090	COG0582	viral genome integration into host DNA
EXW31_RS12100	COG0189	ligase activity
EXW31_RS12120	COG1396	sequence-specific DNA binding
EXW31_RS12220	COG1309	transcriptional regulator
EXW31_RS12235	COG1136	(ABC) transporter
EXW31_RS12235	COG0577	efflux transmembrane transporter activity
EXW31_RS12240	COG3615	Tellurite resistance protein tehB
EXW31_RS12240	COG0500	methyltransferase
EXW31_RS12250	COG0693	protein deglycase activity
EXW31_RS12310	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW31_RS12315	COG0110	maltose O-acetyltransferase activity
EXW31_RS12320	COG1686	Belongs to the peptidase S11 family
EXW31_RS12365	COG0768	penicillin binding
EXW31_RS12370	COG1595	DNA-templated transcription, initiation
EXW31_RS12380	COG0768	penicillin binding
EXW31_RS12385	COG0768	penicillin binding
EXW31_RS12405	COG1136	(ABC) transporter
EXW31_RS12440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS12450	COG5002	protein histidine kinase activity
EXW31_RS12480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS12495	COG0697	spore germination
EXW31_RS12515	COG3397	chitin binding
EXW31_RS12520	COG0823	Involved in the tonB-independent uptake of proteins
EXW31_RS12530	COG1408	metallophosphoesterase
EXW31_RS12540	COG1131	(ABC) transporter
EXW31_RS12550	COG1309	transcriptional regulator
EXW31_RS12555	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS12560	COG0439	Biotin carboxylase
EXW31_RS12565	COG0511	ligase activity, forming carbon-carbon bonds
EXW31_RS12570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW31_RS12575	COG1024	Enoyl-CoA hydratase
EXW31_RS12580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW31_RS12585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW31_RS12640	COG1686	Belongs to the peptidase S11 family
EXW31_RS12675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW31_RS12700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW31_RS12730	COG1733	regulation of RNA biosynthetic process
EXW31_RS12735	COG2226	methyltransferase
EXW31_RS12745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW31_RS12775	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW31_RS12790	COG0697	spore germination
EXW31_RS12795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS12830	COG2323	membrane
EXW31_RS12835	COG2132	Multicopper oxidase
EXW31_RS12850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS12855	COG0697	spore germination
EXW31_RS12860	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW31_RS12865	COG0201	protein transport
EXW31_RS12875	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS12880	COG3227	Zinc metalloprotease (Elastase)
EXW31_RS12885	COG1523	belongs to the glycosyl hydrolase 13 family
EXW31_RS12890	COG1073	alpha beta
EXW31_RS12900	COG0577	efflux transmembrane transporter activity
EXW31_RS12905	COG1136	(ABC) transporter
EXW31_RS12925	COG5002	protein histidine kinase activity
EXW31_RS12930	COG0745	RESPONSE REGULATOR receiver
EXW31_RS12935	COG1011	Hydrolase
EXW31_RS12960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW31_RS12965	COG1183	phosphatidylcholine synthase activity
EXW31_RS12975	COG1132	(ABC) transporter
EXW31_RS12985	COG3961	Belongs to the TPP enzyme family
EXW31_RS13005	COG0322	excinuclease ABC activity
EXW31_RS13030	COG2318	DinB family
EXW31_RS13045	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW31_RS13065	COG3878	Protein conserved in bacteria
EXW31_RS13075	COG0406	alpha-ribazole phosphatase activity
EXW31_RS13095	COG1051	belongs to the nudix hydrolase family
EXW31_RS13100	COG0592	DNA-directed DNA polymerase activity
EXW31_RS13115	COG2223	nitrite transmembrane transporter activity
EXW31_RS13125	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW31_RS13135	COG0494	nUDIX hydrolase
EXW31_RS13165	COG0584	glycerophosphoryl diester phosphodiesterase
EXW31_RS13180	COG2814	Major facilitator Superfamily
EXW31_RS13225	COG0768	penicillin binding
EXW31_RS13230	COG0671	phosphoesterase, PA-phosphatase related
EXW31_RS13235	COG0604	alcohol dehydrogenase
EXW31_RS13240	COG5002	protein histidine kinase activity
EXW31_RS13245	COG0745	RESPONSE REGULATOR receiver
EXW31_RS13255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW31_RS13265	COG2205	protein histidine kinase activity
EXW31_RS13280	COG1122	ATPase activity
EXW31_RS13285	COG4720	Psort location CytoplasmicMembrane, score
EXW31_RS13290	COG1794	racemase activity, acting on amino acids and derivatives
EXW31_RS13295	COG1819	glycosyl
EXW31_RS13305	COG0768	penicillin binding
EXW31_RS13310	COG5002	protein histidine kinase activity
EXW31_RS13315	COG0561	phosphatase activity
EXW31_RS13350	COG2124	cytochrome p450
EXW31_RS13380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW31_RS13390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS13395	COG0460	homoserine dehydrogenase
EXW31_RS13415	COG0577	efflux transmembrane transporter activity
EXW31_RS13420	COG1136	(ABC) transporter
EXW31_RS13435	COG0488	(ABC) transporter
EXW31_RS13440	COG0667	Aldo Keto reductase
EXW31_RS13445	COG0583	DNA-binding transcription factor activity
EXW31_RS13450	COG2205	protein histidine kinase activity
EXW31_RS13455	COG0745	RESPONSE REGULATOR receiver
EXW31_RS13465	COG3773	Cell wall hydrolase
EXW31_RS13470	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW31_RS13510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS13525	COG2959	enzyme of heme biosynthesis
EXW31_RS13550	COG3483	tryptophan 2,3-dioxygenase activity
EXW31_RS13560	COG3844	kynureninase activity
EXW31_RS13565	COG1309	transcriptional regulator
EXW31_RS13585	COG1349	DNA-binding transcription factor activity
EXW31_RS13605	COG2223	nitrite transmembrane transporter activity
EXW31_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS13650	COG4176	ABC-type proline glycine betaine transport system permease component
EXW31_RS13655	COG0517	IMP dehydrogenase activity
EXW31_RS13655	COG4175	Glycine betaine
EXW31_RS13680	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW31_RS13685	COG2153	protein acetylation
EXW31_RS13690	COG1819	glycosyl
EXW31_RS13710	COG2205	protein histidine kinase activity
EXW31_RS13715	COG2315	Protein conserved in bacteria
EXW31_RS13740	COG3344	reverse transcriptase
EXW31_RS13770	COG3973	AAA domain
EXW31_RS13775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW31_RS13795	COG0514	ATP-dependent DNA helicase (RecQ)
EXW31_RS13825	COG4637	Psort location Cytoplasmic, score
EXW31_RS13835	COG1227	inorganic diphosphatase activity
EXW31_RS13840	COG2318	DinB family
EXW31_RS13855	COG1162	GTPase activity
EXW31_RS13860	COG1115	amino acid carrier protein
EXW31_RS13865	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS13870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW31_RS13880	COG3938	Belongs to the proline racemase family
EXW31_RS13885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW31_RS13930	COG1078	dGTPase activity
EXW31_RS13935	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS13955	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW31_RS13960	COG4166	transmembrane transport
EXW31_RS13970	COG4948	Mandelate Racemase Muconate Lactonizing
EXW31_RS13990	COG0667	Aldo Keto reductase
EXW31_RS14040	COG2936	dipeptidyl-peptidase activity
EXW31_RS14050	COG0745	RESPONSE REGULATOR receiver
EXW31_RS14075	COG1164	Oligoendopeptidase f
EXW31_RS14100	COG1307	EDD domain protein, DegV family
EXW31_RS14135	COG2814	Major facilitator Superfamily
EXW31_RS14145	COG1664	Polymer-forming cytoskeletal
EXW31_RS14150	COG0789	Transcriptional regulator
EXW31_RS14155	COG4533	DNA binding
EXW31_RS14160	COG2814	Major facilitator Superfamily
EXW31_RS14160	COG0477	Major facilitator Superfamily
EXW31_RS14175	COG2261	transglycosylase associated protein
EXW31_RS14190	COG2226	methyltransferase
EXW31_RS14225	COG0436	Aminotransferase
EXW31_RS14230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW31_RS14240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW31_RS14255	COG1131	(ABC) transporter
EXW31_RS14305	COG0628	permease
EXW31_RS14330	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW31_RS14335	COG2720	vancomycin resistance protein
EXW31_RS14355	COG0697	spore germination
EXW31_RS14375	COG4912	Dna alkylation repair
EXW31_RS14415	COG1368	sulfuric ester hydrolase activity
EXW31_RS14420	COG0488	(ABC) transporter
EXW31_RS14425	COG1033	growth of symbiont in host cell
EXW31_RS14425	COG2409	Drug exporters of the RND superfamily
EXW31_RS14430	COG1309	transcriptional regulator
EXW31_RS14445	COG0287	Prephenate dehydrogenase
EXW31_RS14460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW31_RS14460	COG1605	Chorismate mutase
EXW31_RS14495	COG1388	LysM domain
EXW31_RS14495	COG3584	3D domain protein
EXW31_RS14505	COG0346	lactoylglutathione lyase activity
EXW31_RS14515	COG0277	FAD linked oxidase domain protein
EXW31_RS14535	COG2610	gluconate transmembrane transporter activity
EXW31_RS14540	COG1024	Enoyl-CoA hydratase
EXW31_RS14550	COG3290	protein histidine kinase activity
EXW31_RS14550	COG3829	transcription factor binding
EXW31_RS14560	COG0579	oxidoreductase
EXW31_RS14565	COG1879	ABC-type sugar transport system periplasmic component
EXW31_RS14575	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW31_RS14585	COG2390	Transcriptional regulator
EXW31_RS14590	COG1070	Carbohydrate kinase
EXW31_RS14605	COG2226	methyltransferase
EXW31_RS14630	COG0346	lactoylglutathione lyase activity
EXW31_RS14635	COG2329	Antibiotic biosynthesis monooxygenase
EXW31_RS14655	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW31_RS14660	COG2207	Transcriptional regulator
EXW31_RS14665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS14670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW31_RS14675	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW31_RS14680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW31_RS14685	COG3239	Fatty acid desaturase
EXW31_RS14705	COG3842	ATPase activity
EXW31_RS14730	COG1175	transmembrane transport
EXW31_RS14735	COG1349	DNA-binding transcription factor activity
EXW31_RS14745	COG3655	Transcriptional regulator
EXW31_RS14765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS14770	COG0346	lactoylglutathione lyase activity
EXW31_RS14800	COG0714	Associated with various cellular activities
EXW31_RS14820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW31_RS14825	COG0753	catalase activity
EXW31_RS14865	COG0714	Associated with various cellular activities
EXW31_RS14875	COG0778	Nitroreductase
EXW31_RS14880	COG1846	Transcriptional regulator
EXW31_RS14900	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW31_RS14920	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS14925	COG0183	Belongs to the thiolase family
EXW31_RS14930	COG1024	Enoyl-CoA hydratase
EXW31_RS14935	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW31_RS14940	COG2723	6-phospho-beta-galactosidase activity
EXW31_RS14945	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW31_RS14950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS14965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS14975	COG2508	Transcriptional regulator
EXW31_RS14980	COG2814	Major facilitator Superfamily
EXW31_RS15010	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS15015	COG1309	transcriptional regulator
EXW31_RS15040	COG0456	acetyltransferase
EXW31_RS15055	COG0697	spore germination
EXW31_RS15060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS15065	COG1671	Belongs to the UPF0178 family
EXW31_RS15080	COG0642	Histidine kinase
EXW31_RS15085	COG0745	RESPONSE REGULATOR receiver
EXW31_RS15090	COG0596	Alpha beta hydrolase
EXW31_RS15100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW31_RS15100	COG0456	acetyltransferase
EXW31_RS15125	COG0730	response to heat
EXW31_RS15135	COG0833	amino acid
EXW31_RS15145	COG4335	DNA alkylation repair
EXW31_RS15165	COG0681	Belongs to the peptidase S26 family
EXW31_RS15170	COG0768	penicillin binding
EXW31_RS15185	COG3104	oligopeptide transport
EXW31_RS15190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW31_RS15205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW31_RS15210	COG1984	allophanate hydrolase subunit 2
EXW31_RS15215	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW31_RS15220	COG1414	Transcriptional regulator
EXW31_RS15240	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS15275	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW31_RS15300	COG0574	Belongs to the PEP-utilizing enzyme family
EXW31_RS15300	COG3848	Pyruvate phosphate dikinase
EXW31_RS15350	COG0798	PFAM Bile acid sodium symporter
EXW31_RS15355	COG0346	lactoylglutathione lyase activity
EXW31_RS15360	COG0640	Transcriptional regulator
EXW31_RS15375	COG1309	transcriptional regulator
EXW31_RS15380	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS15385	COG1522	sequence-specific DNA binding
EXW31_RS15400	COG0346	lactoylglutathione lyase activity
EXW31_RS15415	COG0457	Tetratricopeptide repeat
EXW31_RS15430	COG0745	RESPONSE REGULATOR receiver
EXW31_RS15435	COG5002	protein histidine kinase activity
EXW31_RS15435	COG3850	Histidine kinase
EXW31_RS15475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW31_RS15480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW31_RS15495	COG2226	methyltransferase
EXW31_RS15515	COG1136	(ABC) transporter
EXW31_RS15520	COG0577	efflux transmembrane transporter activity
EXW31_RS15540	COG3850	Histidine kinase
EXW31_RS15540	COG5002	protein histidine kinase activity
EXW31_RS15555	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS15560	COG2271	Major facilitator Superfamily
EXW31_RS15565	COG1556	Lactate utilization protein
EXW31_RS15570	COG1139	Iron-sulfur cluster binding protein
EXW31_RS15580	COG0583	DNA-binding transcription factor activity
EXW31_RS15585	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW31_RS15600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW31_RS15620	COG1595	DNA-templated transcription, initiation
EXW31_RS15650	COG2814	Major facilitator Superfamily
EXW31_RS15680	COG1876	peptidase activity
EXW31_RS15685	COG2843	Capsule synthesis protein
EXW31_RS15700	COG0477	Major facilitator Superfamily
EXW31_RS15715	COG1846	Transcriptional regulator
EXW31_RS15720	COG2814	Major facilitator Superfamily
EXW31_RS15915	COG4187	Peptidase family M20/M25/M40
EXW31_RS15920	COG1414	Transcriptional regulator
EXW31_RS15925	COG0833	amino acid
EXW31_RS15945	COG2031	fatty acid transporter
EXW31_RS15955	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS16015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW31_RS16020	COG2356	endonuclease I
EXW31_RS16025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW31_RS16035	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW31_RS16055	COG1785	Belongs to the alkaline phosphatase family
EXW31_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS16080	COG1131	(ABC) transporter
EXW31_RS16105	COG1011	Hydrolase
EXW31_RS16110	COG2365	Tyrosine phosphatase family
EXW31_RS16140	COG0628	permease
EXW31_RS16170	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW31_RS16180	COG1253	flavin adenine dinucleotide binding
EXW31_RS16185	COG0789	Transcriptional regulator
EXW31_RS16190	COG0697	spore germination
EXW31_RS16195	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW31_RS16200	COG3813	Protein conserved in bacteria
EXW31_RS16205	COG4702	Belongs to the UPF0303 family
EXW31_RS16215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS16225	COG0494	nUDIX hydrolase
EXW31_RS16240	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS16250	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS16255	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS16260	COG1733	regulation of RNA biosynthetic process
EXW31_RS16265	COG0640	Transcriptional regulator
EXW31_RS16285	COG1191	sigma factor activity
EXW31_RS16310	COG5002	protein histidine kinase activity
EXW31_RS16315	COG0745	RESPONSE REGULATOR receiver
EXW31_RS16340	COG0657	acetylesterase activity
EXW31_RS16350	COG2814	Major facilitator Superfamily
EXW31_RS16355	COG1309	transcriptional regulator
EXW31_RS16370	COG2224	Isocitrate lyase
EXW31_RS16410	COG0814	amino acid
EXW31_RS16435	COG1151	hydroxylamine reductase activity
EXW31_RS16440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS16465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW31_RS16475	COG2072	flavoprotein involved in K transport
EXW31_RS16520	COG0714	Associated with various cellular activities
EXW31_RS16575	COG1695	Transcriptional regulator
EXW31_RS16580	COG0604	alcohol dehydrogenase
EXW31_RS16585	COG1113	amino acid transport
EXW31_RS16590	COG0456	acetyltransferase
EXW31_RS16605	COG5002	protein histidine kinase activity
EXW31_RS16610	COG0745	RESPONSE REGULATOR receiver
EXW31_RS16615	COG5002	protein histidine kinase activity
EXW31_RS16620	COG2814	Major facilitator Superfamily
EXW31_RS16630	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW31_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS16645	COG0534	Mate efflux family protein
EXW31_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS16655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW31_RS16670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW31_RS16675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW31_RS16690	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS16695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS16700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS16705	COG3739	integral membrane protein
EXW31_RS16720	COG0583	DNA-binding transcription factor activity
EXW31_RS16740	COG1193	negative regulation of DNA recombination
EXW31_RS16750	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW31_RS16755	COG1164	Oligoendopeptidase f
EXW31_RS16780	COG3781	membrane
EXW31_RS16795	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW31_RS16870	COG0640	Transcriptional regulator
EXW31_RS16875	COG0604	alcohol dehydrogenase
EXW31_RS16880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW31_RS16905	COG2808	Putative FMN-binding domain
EXW31_RS16910	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW31_RS16920	COG0277	FAD linked oxidase domain protein
EXW31_RS16940	COG1285	pathogenesis
EXW31_RS16950	COG2514	catechol 2,3-dioxygenase activity
EXW31_RS16955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS16960	COG1126	abc transporter atp-binding protein
EXW31_RS16965	COG0765	amino acid transport
EXW31_RS16970	COG2720	vancomycin resistance protein
EXW31_RS16985	COG0110	maltose O-acetyltransferase activity
EXW31_RS16995	COG1278	Cold shock
EXW31_RS17005	COG0716	FMN binding
EXW31_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS17045	COG0165	Argininosuccinate lyase
EXW31_RS17060	COG4145	pantothenate transmembrane transporter activity
EXW31_RS17070	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS17085	COG1657	PFAM Prenyltransferase squalene oxidase
EXW31_RS17090	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW31_RS17095	COG2962	Rard protein
EXW31_RS17100	COG3326	Membrane
EXW31_RS17105	COG0531	amino acid
EXW31_RS17130	COG1737	Transcriptional regulator
EXW31_RS17135	COG2971	BadF BadG BcrA BcrD
EXW31_RS17145	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW31_RS17150	COG1486	melibiose metabolic process
EXW31_RS17160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS17185	COG2226	methyltransferase
EXW31_RS17190	COG4166	transmembrane transport
EXW31_RS17195	COG4166	transmembrane transport
EXW31_RS17200	COG4166	transmembrane transport
EXW31_RS17205	COG1316	TRANSCRIPTIONal
EXW31_RS17215	COG1595	DNA-templated transcription, initiation
EXW31_RS17225	COG1131	(ABC) transporter
EXW31_RS17235	COG0673	inositol 2-dehydrogenase activity
EXW31_RS17240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW31_RS17245	COG0187	DNA topoisomerase II activity
EXW31_RS17250	COG1832	CoA-binding protein
EXW31_RS17255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW31_RS17260	COG0745	RESPONSE REGULATOR receiver
EXW31_RS17270	COG1328	CTP reductase activity
EXW31_RS17280	COG4841	protein insertion into membrane
EXW31_RS17285	COG0824	Thioesterase
EXW31_RS17310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW31_RS17325	COG1132	(ABC) transporter
EXW31_RS17330	COG1266	CAAX protease self-immunity
EXW31_RS17335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW31_RS17365	COG2211	Major facilitator Superfamily
EXW31_RS17375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW31_RS17390	COG0183	Belongs to the thiolase family
EXW31_RS17395	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS17400	COG1268	BioY protein
EXW31_RS17405	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS17410	COG1396	sequence-specific DNA binding
EXW31_RS17445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS17455	COG5002	protein histidine kinase activity
EXW31_RS17465	COG0400	carboxylic ester hydrolase activity
EXW31_RS17475	COG0069	glutamate synthase activity
EXW31_RS17480	COG1902	pentaerythritol trinitrate reductase activity
EXW31_RS17485	COG1329	Transcriptional regulator
EXW31_RS17490	COG0010	Belongs to the arginase family
EXW31_RS17500	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW31_RS17505	COG2986	histidine ammonia-lyase
EXW31_RS17515	COG2226	methyltransferase
EXW31_RS17540	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW31_RS17545	COG0785	Cytochrome C biogenesis protein
EXW31_RS17555	COG1473	amidohydrolase
EXW31_RS17560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW31_RS17565	COG1131	(ABC) transporter
EXW31_RS17580	COG0583	DNA-binding transcription factor activity
EXW31_RS17590	COG1346	cytolysis
EXW31_RS17605	COG0730	response to heat
EXW31_RS17630	COG1132	(ABC) transporter
EXW31_RS17635	COG1132	(ABC) transporter
EXW31_RS17640	COG3763	UPF0154 protein
EXW31_RS17655	COG3639	organic phosphonate transmembrane transporter activity
EXW31_RS17660	COG3639	organic phosphonate transmembrane transporter activity
EXW31_RS17670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS17675	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS17685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW31_RS17690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW31_RS17705	COG1695	Transcriptional regulator
EXW31_RS17710	COG1132	(ABC) transporter
EXW31_RS17740	COG0367	asparagine synthase
EXW31_RS17745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW31_RS17755	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW31_RS17760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW31_RS17770	COG3420	alginic acid biosynthetic process
EXW31_RS17770	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW31_RS17775	COG1216	Glycosyl transferase, family 2
EXW31_RS17775	COG1442	glycosyl transferase family 8
EXW31_RS17800	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS17810	COG1215	transferase activity, transferring glycosyl groups
EXW31_RS17815	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS17820	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS17825	COG1086	Polysaccharide biosynthesis protein
EXW31_RS17830	COG0489	protein tyrosine kinase activity
EXW31_RS17840	COG0174	glutamine synthetase
EXW31_RS17845	COG0789	Transcriptional regulator
EXW31_RS17850	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW31_RS17855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW31_RS17860	COG2860	membrane
EXW31_RS17870	COG0464	growth
EXW31_RS17895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW31_RS17905	COG3584	3D domain protein
EXW31_RS17905	COG1388	LysM domain
EXW31_RS17910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW31_RS17910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW31_RS17910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW31_RS17915	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW31_RS17920	COG1349	DNA-binding transcription factor activity
EXW31_RS17925	COG1979	alcohol dehydrogenase
EXW31_RS17930	COG2322	membrane
EXW31_RS17940	COG1473	amidohydrolase
EXW31_RS17945	COG1408	metallophosphoesterase
EXW31_RS17960	COG2217	Heavy metal translocating P-type atpase
EXW31_RS17965	COG2608	mercury ion transmembrane transporter activity
EXW31_RS17970	COG1937	Protein conserved in bacteria
EXW31_RS18000	COG2819	hydrolase of the alpha beta superfamily
EXW31_RS18005	COG1120	ATPase activity
EXW31_RS18010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS18015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS18020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS18025	COG0708	Exodeoxyribonuclease III
EXW31_RS18030	COG2169	Transcriptional regulator
EXW31_RS18035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW31_RS18040	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW31_RS18045	COG2706	6-phosphogluconolactonase activity
EXW31_RS18050	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW31_RS18055	COG2364	Membrane
EXW31_RS18070	COG0346	lactoylglutathione lyase activity
EXW31_RS18075	COG5001	Diguanylate cyclase
EXW31_RS18075	COG3300	MHYT domain
EXW31_RS18110	COG1346	cytolysis
EXW31_RS18120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW31_RS18125	COG2945	thiolester hydrolase activity
EXW31_RS18125	COG0596	Alpha beta hydrolase
EXW31_RS18130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW31_RS18140	COG2188	Transcriptional regulator
EXW31_RS18145	COG2723	6-phospho-beta-galactosidase activity
EXW31_RS18155	COG3773	Cell wall hydrolase
EXW31_RS18165	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW31_RS18175	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW31_RS18180	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW31_RS18190	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW31_RS18195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW31_RS18200	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW31_RS18205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW31_RS18205	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW31_RS18215	COG2359	stage V sporulation protein S
EXW31_RS18220	COG1692	metallophosphoesterase
EXW31_RS18225	COG1418	mRNA catabolic process
EXW31_RS18230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW31_RS18235	COG1058	Belongs to the CinA family
EXW31_RS18235	COG1546	Belongs to the CinA family
EXW31_RS18240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW31_RS18245	COG1426	Protein conserved in bacteria
EXW31_RS18260	COG0300	oxidoreductase activity
EXW31_RS18265	COG0612	Peptidase, M16
EXW31_RS18270	COG0612	Peptidase, M16
EXW31_RS18275	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW31_RS18280	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW31_RS18285	COG3845	ABC transporter
EXW31_RS18290	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW31_RS18295	COG2188	Transcriptional regulator
EXW31_RS18305	COG1674	ftsk spoiiie
EXW31_RS18315	COG0740	serine-type endopeptidase activity
EXW31_RS18320	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW31_RS18330	COG0527	aspartate kinase activity
EXW31_RS18335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW31_RS18340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW31_RS18345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW31_RS18350	COG1873	PFAM PRC-barrel domain
EXW31_RS18355	COG0612	Peptidase, M16
EXW31_RS18360	COG0726	polysaccharide deacetylase
EXW31_RS18365	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW31_RS18375	COG0196	riboflavin kinase activity
EXW31_RS18385	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW31_RS18390	COG1550	Protein conserved in bacteria
EXW31_RS18395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW31_RS18400	COG1358	cellular component organization or biogenesis
EXW31_RS18405	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW31_RS18410	COG0195	Participates in both transcription termination and antitermination
EXW31_RS18425	COG0442	prolyl-tRNA aminoacylation
EXW31_RS18430	COG0750	zinc metalloprotease
EXW31_RS18440	COG4589	Belongs to the CDS family
EXW31_RS18450	COG0233	cytoplasmic translational termination
EXW31_RS18455	COG0528	UMP kinase activity
EXW31_RS18460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW31_RS18465	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW31_RS18470	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW31_RS18475	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW31_RS18480	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW31_RS18485	COG4974	Belongs to the 'phage' integrase family
EXW31_RS18490	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW31_RS18495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW31_RS18500	COG0758	DNA mediated transformation
EXW31_RS18505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW31_RS18510	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW31_RS18515	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW31_RS18530	COG0335	large ribosomal subunit rRNA binding
EXW31_RS18535	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW31_RS18540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW31_RS18545	COG1837	Belongs to the UPF0109 family
EXW31_RS18555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW31_RS18565	COG0552	protein localization to endoplasmic reticulum
EXW31_RS18570	COG1196	nuclear chromosome segregation
EXW31_RS18575	COG0571	ribonuclease III activity
EXW31_RS18580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW31_RS18585	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS18590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW31_RS18595	COG0416	fatty acid biosynthetic process
EXW31_RS18605	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW31_RS18610	COG1461	Dihydroxyacetone kinase
EXW31_RS18615	COG1302	Protein conserved in bacteria
EXW31_RS18630	COG1564	THIamine pyrophosphokinase
EXW31_RS18635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW31_RS18645	COG2815	serine threonine protein kinase
EXW31_RS18645	COG0515	serine threonine protein kinase
EXW31_RS18650	COG0631	protein serine/threonine phosphatase activity
EXW31_RS18655	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW31_RS18660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW31_RS18660	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW31_RS18665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW31_RS18670	COG0242	peptide deformylase activity
EXW31_RS18675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW31_RS18680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW31_RS18685	COG1758	RNA polymerase activity
EXW31_RS18700	COG1561	YicC-like family, N-terminal region
EXW31_RS18705	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW31_RS18720	COG0006	proline dipeptidase activity
EXW31_RS18735	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW31_RS18760	COG0167	dihydroorotate dehydrogenase activity
EXW31_RS18765	COG0543	2 iron, 2 sulfur cluster binding
EXW31_RS18770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW31_RS18780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW31_RS18785	COG0540	Belongs to the ATCase OTCase family
EXW31_RS18795	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW31_RS18800	COG0564	pseudouridine synthase activity
EXW31_RS18820	COG3599	regulation of cell shape
EXW31_RS18825	COG2302	S4 RNA-binding domain
EXW31_RS18830	COG0762	integral membrane protein
EXW31_RS18835	COG1799	cell septum assembly
EXW31_RS18840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW31_RS18850	COG1873	PFAM PRC-barrel domain
EXW31_RS18855	COG1191	sigma factor activity
EXW31_RS18860	COG1191	sigma factor activity
EXW31_RS18870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW31_RS18875	COG0849	cell division
EXW31_RS18880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW31_RS18895	COG0772	Belongs to the SEDS family
EXW31_RS18900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW31_RS18905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW31_RS18910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW31_RS18915	COG0768	penicillin binding
EXW31_RS18920	COG0768	penicillin binding
EXW31_RS18930	COG0275	rRNA processing
EXW31_RS18935	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW31_RS18940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW31_RS18945	COG0454	-acetyltransferase
EXW31_RS18955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW31_RS18960	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW31_RS18965	COG1323	Belongs to the UPF0348 family
EXW31_RS18970	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW31_RS18975	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW31_RS18980	COG3314	Sporulation integral membrane protein YlbJ
EXW31_RS18990	COG0742	ribosomal rna small subunit methyltransferase
EXW31_RS19000	COG4471	UPF0298 protein
EXW31_RS19005	COG3679	Belongs to the UPF0342 family
EXW31_RS19010	COG0406	alpha-ribazole phosphatase activity
EXW31_RS19025	COG2340	Cysteine-rich secretory protein family
EXW31_RS19035	COG3336	cytochrome c oxidase
EXW31_RS19050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW31_RS19060	COG0109	protoheme IX farnesyltransferase activity
EXW31_RS19065	COG1612	heme a metabolic process
EXW31_RS19070	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW31_RS19075	COG0772	Belongs to the SEDS family
EXW31_RS19080	COG4838	Belongs to the UPF0358 family
EXW31_RS19085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW31_RS19090	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW31_RS19100	COG4896	Protein conserved in bacteria
EXW31_RS19115	COG1217	gtp-binding protein TYPA
EXW31_RS19125	COG0483	inositol monophosphate 1-phosphatase activity
EXW31_RS19135	COG4493	Belongs to the UPF0637 family
EXW31_RS19140	COG4476	Belongs to the UPF0223 family
EXW31_RS19145	COG1982	Orn Lys Arg decarboxylase major
EXW31_RS19195	COG0022	dehydrogenase e1 component
EXW31_RS19200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW31_RS19215	COG0561	phosphatase activity
EXW31_RS19220	COG5503	Protein of unknown function (DUF1447)
EXW31_RS19225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW31_RS19230	COG0569	domain protein
EXW31_RS19240	COG1473	amidohydrolase
EXW31_RS19245	COG2171	N-acyltransferase activity
EXW31_RS19250	COG0583	DNA-binding transcription factor activity
EXW31_RS19255	COG0517	IMP dehydrogenase activity
EXW31_RS19265	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW31_RS19275	COG4703	Protein of unknown function (DUF1797)
EXW31_RS19290	COG2200	EAL domain
EXW31_RS19295	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS19300	COG1408	metallophosphoesterase
EXW31_RS19345	COG2814	Major facilitator Superfamily
EXW31_RS19355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW31_RS19365	COG3209	COG3209 Rhs family protein
EXW31_RS19375	COG2205	protein histidine kinase activity
EXW31_RS19385	COG0436	Aminotransferase
EXW31_RS19390	COG1609	Transcriptional regulator
EXW31_RS19395	COG3833	ABC-type maltose transport systems, permease component
EXW31_RS19400	COG1175	transmembrane transport
EXW31_RS19405	COG2182	Extracellular solute-binding protein
EXW31_RS19415	COG0366	Alpha amylase catalytic
EXW31_RS19420	COG3842	ATPase activity
EXW31_RS19425	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS19465	COG0183	Belongs to the thiolase family
EXW31_RS19500	COG1695	Transcriptional regulator
EXW31_RS19505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS19515	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW31_RS19525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW31_RS19530	COG0436	Aminotransferase
EXW31_RS19535	COG1850	ribulose-bisphosphate carboxylase activity
EXW31_RS19540	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW31_RS19545	COG0235	Class ii aldolase
EXW31_RS19550	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW31_RS19565	COG2084	Dehydrogenase
EXW31_RS19575	COG2199	diguanylate cyclase activity
EXW31_RS19580	COG0778	Nitroreductase
EXW31_RS19605	COG2190	(PTS) system
EXW31_RS19605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS19605	COG1263	PTS System
EXW31_RS19610	COG3711	transcriptional antiterminator
EXW31_RS19620	COG2188	Transcriptional regulator
EXW31_RS19625	COG0363	glucosamine-6-phosphate deaminase activity
EXW31_RS19630	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW31_RS19640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW31_RS19645	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW31_RS19655	COG1547	Domain of unknown function (DUF309)
EXW31_RS19665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW31_RS19670	COG4086	secreted protein
EXW31_RS19675	COG0561	phosphatase activity
EXW31_RS19680	COG0697	spore germination
EXW31_RS19695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW31_RS19735	COG1686	Belongs to the peptidase S11 family
EXW31_RS19740	COG1725	Transcriptional regulator
EXW31_RS19745	COG1131	(ABC) transporter
EXW31_RS19765	COG1846	Transcriptional regulator
EXW31_RS19780	COG0598	Magnesium transport protein CorA
EXW31_RS19795	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW31_RS19805	COG4974	Belongs to the 'phage' integrase family
EXW31_RS19815	COG0735	belongs to the Fur family
EXW31_RS19820	COG1300	Membrane
EXW31_RS19840	COG0667	Aldo Keto reductase
EXW31_RS19845	COG0656	L-ascorbic acid biosynthetic process
EXW31_RS19850	COG0456	acetyltransferase
EXW31_RS19850	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW31_RS19860	COG1525	nuclease
EXW31_RS19860	COG4085	toxin activity
EXW31_RS19860	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS19865	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW31_RS19875	COG0596	Alpha beta hydrolase
EXW31_RS19880	COG2056	Na+-H+ antiporter family
EXW31_RS19885	COG1609	Transcriptional regulator
EXW31_RS19890	COG0456	acetyltransferase
EXW31_RS19895	COG1073	alpha beta
EXW31_RS19910	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW31_RS19910	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW31_RS19915	COG0307	riboflavin synthase, alpha
EXW31_RS19920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW31_RS19920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW31_RS19935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW31_RS19945	COG1073	alpha beta
EXW31_RS19945	COG2226	methyltransferase
EXW31_RS19950	COG0156	8-amino-7-oxononanoate synthase activity
EXW31_RS19960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW31_RS19970	COG1757	Na H antiporter
EXW31_RS19975	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS19985	COG1522	sequence-specific DNA binding
EXW31_RS20015	COG5444	nuclease activity
EXW31_RS20025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW31_RS20030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW31_RS20040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW31_RS20050	COG0300	oxidoreductase activity
EXW31_RS20055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS20060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW31_RS20065	COG1760	l-serine dehydratase
EXW31_RS20070	COG1760	l-serine dehydratase
EXW31_RS20080	COG1234	tRNA 3'-trailer cleavage
EXW31_RS20110	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW31_RS20115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS20130	COG1376	ErfK ybiS ycfS ynhG family protein
EXW31_RS20135	COG4129	membrane
EXW31_RS20140	COG1126	abc transporter atp-binding protein
EXW31_RS20145	COG0765	amino acid transport
EXW31_RS20150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW31_RS20160	COG2816	NAD+ diphosphatase activity
EXW31_RS20165	COG2323	membrane
EXW31_RS20170	COG0772	Belongs to the SEDS family
EXW31_RS20175	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW31_RS20180	COG0022	dehydrogenase e1 component
EXW31_RS20185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW31_RS20190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW31_RS20195	COG3426	butyrate kinase activity
EXW31_RS20205	COG0280	phosphate acetyltransferase
EXW31_RS20210	COG3290	protein histidine kinase activity
EXW31_RS20210	COG3829	transcription factor binding
EXW31_RS20220	COG0584	glycerophosphoryl diester phosphodiesterase
EXW31_RS20225	COG3093	addiction module antidote protein HigA
EXW31_RS20235	COG0745	RESPONSE REGULATOR receiver
EXW31_RS20240	COG0750	zinc metalloprotease
EXW31_RS20245	COG0497	DNA recombination
EXW31_RS20250	COG1438	arginine binding
EXW31_RS20255	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW31_RS20260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW31_RS20265	COG0142	geranyltranstransferase activity
EXW31_RS20270	COG1722	exodeoxyribonuclease VII activity
EXW31_RS20280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW31_RS20285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW31_RS20290	COG1302	Protein conserved in bacteria
EXW31_RS20295	COG0439	Biotin carboxylase
EXW31_RS20300	COG0511	ligase activity, forming carbon-carbon bonds
EXW31_RS20345	COG3854	ATPases associated with a variety of cellular activities
EXW31_RS20365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW31_RS20370	COG0006	proline dipeptidase activity
EXW31_RS20385	COG3872	metal-dependent enzyme
EXW31_RS20395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW31_RS20435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW31_RS20445	COG1609	Transcriptional regulator
EXW31_RS20455	COG2076	Multidrug Resistance protein
EXW31_RS20460	COG2076	Multidrug Resistance protein
EXW31_RS20500	COG1725	Transcriptional regulator
EXW31_RS20515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW31_RS20520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW31_RS20525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW31_RS20530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW31_RS20560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW31_RS20585	COG4970	Tfp pilus assembly protein FimT
EXW31_RS20590	COG4537	Required for transformation and DNA binding
EXW31_RS20595	COG1459	type II secretion system
EXW31_RS20600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW31_RS20655	COG0646	methionine synthase
EXW31_RS20655	COG1410	methionine synthase
EXW31_RS20660	COG0646	methionine synthase
EXW31_RS20660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW31_RS20665	COG0626	cystathionine gamma-synthase activity
EXW31_RS20670	COG0626	cystathionine gamma-synthase activity
EXW31_RS20690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS20700	COG1940	carbohydrate kinase activity
EXW31_RS20705	COG4483	Protein conserved in bacteria
EXW31_RS20710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW31_RS20715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW31_RS20720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW31_RS20725	COG0704	Plays a role in the regulation of phosphate uptake
EXW31_RS20735	COG0581	inorganic phosphate transmembrane transporter activity
EXW31_RS20740	COG0573	inorganic phosphate transmembrane transporter activity
EXW31_RS20745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW31_RS20750	COG0768	penicillin binding
EXW31_RS20755	COG0477	Major facilitator Superfamily
EXW31_RS20760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW31_RS20775	COG1388	LysM domain
EXW31_RS20780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW31_RS20785	COG0735	belongs to the Fur family
EXW31_RS20790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW31_RS20795	COG1121	(ABC) transporter
EXW31_RS20800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS20810	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW31_RS20830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW31_RS20835	COG2384	SAM-dependent methyltransferase
EXW31_RS20840	COG2010	Cytochrome c
EXW31_RS20845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW31_RS20850	COG0358	DNA primase activity
EXW31_RS20860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW31_RS20865	COG0517	IMP dehydrogenase activity
EXW31_RS20870	COG1381	Involved in DNA repair and RecF pathway recombination
EXW31_RS20880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW31_RS20885	COG0295	cytidine deaminase activity
EXW31_RS20890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW31_RS20895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW31_RS20900	COG1480	7TM receptor with intracellular HD hydrolase
EXW31_RS20905	COG1702	phosphate starvation-inducible protein PhoH
EXW31_RS20920	COG1610	YqeY-like protein
EXW31_RS20925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW31_RS20930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW31_RS20935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW31_RS20945	COG0484	heat shock protein binding
EXW31_RS20950	COG0443	Heat shock 70 kDa protein
EXW31_RS20960	COG1420	regulation of RNA biosynthetic process
EXW31_RS20965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW31_RS20970	COG1733	regulation of RNA biosynthetic process
EXW31_RS20975	COG0481	GTPase activity
EXW31_RS20985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW31_RS20990	COG0268	Binds directly to 16S ribosomal RNA
EXW31_RS20995	COG1466	dna polymerase III delta subunit
EXW31_RS21005	COG0658	competence protein
EXW31_RS21005	COG2333	competence protein COMEC
EXW31_RS21010	COG2131	deaminase
EXW31_RS21015	COG1555	photosystem II stabilization
EXW31_RS21015	COG1596	polysaccharide export
EXW31_RS21020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW31_RS21025	COG2226	methyltransferase
EXW31_RS21030	COG0799	negative regulation of ribosome biogenesis
EXW31_RS21035	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW31_RS21040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW31_RS21045	COG1534	Rna-binding protein
EXW31_RS21050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW31_RS21055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW31_RS21060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW31_RS21070	COG0688	phosphatidylethanolamine metabolic process
EXW31_RS21090	COG2357	RelA SpoT domain protein
EXW31_RS21100	COG1785	Belongs to the alkaline phosphatase family
EXW31_RS21110	COG2267	carboxylic ester hydrolase activity
EXW31_RS21145	COG1404	Belongs to the peptidase S8 family
EXW31_RS21150	COG3186	Phenylalanine-4-hydroxylase
EXW31_RS21160	COG2514	catechol 2,3-dioxygenase activity
EXW31_RS21165	COG2259	Doxx family
EXW31_RS21205	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW31_RS21215	COG1012	belongs to the aldehyde dehydrogenase family
EXW31_RS21215	COG1454	alcohol dehydrogenase
EXW31_RS21220	COG0626	cystathionine gamma-synthase activity
EXW31_RS21225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW31_RS21230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW31_RS21235	COG2226	methyltransferase
EXW31_RS21250	COG0768	penicillin binding
EXW31_RS21260	COG0572	uridine kinase
EXW31_RS21265	COG0826	peptidase U32
EXW31_RS21270	COG0826	peptidase U32
EXW31_RS21275	COG4122	O-methyltransferase activity
EXW31_RS21280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW31_RS21290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW31_RS21300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW31_RS21305	COG0628	permease
EXW31_RS21325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW31_RS21335	COG0482	sulfurtransferase activity
EXW31_RS21340	COG1104	cysteine desulfurase activity
EXW31_RS21345	COG1959	2 iron, 2 sulfur cluster binding
EXW31_RS21350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW31_RS21360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW31_RS21365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW31_RS21380	COG1490	D-aminoacyl-tRNA deacylase activity
EXW31_RS21385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW31_RS21390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW31_RS21395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW31_RS21395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW31_RS21400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW31_RS21405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW31_RS21405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW31_RS21415	COG2244	polysaccharide biosynthetic process
EXW31_RS21420	COG2323	membrane
EXW31_RS21430	COG1862	Preprotein translocase
EXW31_RS21435	COG0343	queuine tRNA-ribosyltransferase activity
EXW31_RS21450	COG2255	four-way junction helicase activity
EXW31_RS21455	COG0632	four-way junction helicase activity
EXW31_RS21460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW31_RS21485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW31_RS21490	COG0157	Belongs to the NadC ModD family
EXW31_RS21495	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW31_RS21500	COG1104	cysteine desulfurase activity
EXW31_RS21505	COG1827	regulation of RNA biosynthetic process
EXW31_RS21510	COG2258	MOSC domain
EXW31_RS21520	COG0077	Prephenate dehydratase
EXW31_RS21525	COG0577	efflux transmembrane transporter activity
EXW31_RS21530	COG0577	efflux transmembrane transporter activity
EXW31_RS21535	COG1136	(ABC) transporter
EXW31_RS21540	COG5002	protein histidine kinase activity
EXW31_RS21545	COG0745	RESPONSE REGULATOR receiver
EXW31_RS21550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW31_RS21555	COG3290	protein histidine kinase activity
EXW31_RS21565	COG2868	ribosomal protein
EXW31_RS21575	COG1530	ribonuclease E activity
EXW31_RS21580	COG1994	Peptidase M50
EXW31_RS21585	COG0739	heme binding
EXW31_RS21590	COG2894	cell division
EXW31_RS21595	COG0850	regulation of cytokinetic process
EXW31_RS21610	COG1077	Cell shape determining protein MreB Mrl
EXW31_RS21615	COG2003	Belongs to the UPF0758 family
EXW31_RS21620	COG0424	maF-like protein
EXW31_RS21630	COG0285	dihydrofolate synthase activity
EXW31_RS21645	COG1388	LysM domain
EXW31_RS21650	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW31_RS21655	COG0113	porphobilinogen synthase activity
EXW31_RS21660	COG1587	Uroporphyrinogen-III synthase
EXW31_RS21665	COG0181	hydroxymethylbilane synthase activity
EXW31_RS21670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW31_RS21675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW31_RS21680	COG1846	Transcriptional regulator
EXW31_RS21685	COG1764	response to oxidative stress
EXW31_RS21690	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW31_RS21700	COG1067	ATP-dependent peptidase activity
EXW31_RS21700	COG0470	DNA polymerase III
EXW31_RS21710	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW31_RS21740	COG0622	Phosphoesterase
EXW31_RS21750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW31_RS21755	COG5401	PFAM Sporulation and spore germination
EXW31_RS21775	COG2197	response regulator
EXW31_RS21780	COG2233	PERMEase
EXW31_RS21785	COG0402	S-adenosylhomocysteine deaminase activity
EXW31_RS21790	COG1983	PspC domain protein
EXW31_RS21795	COG1396	sequence-specific DNA binding
EXW31_RS21800	COG0697	spore germination
EXW31_RS21810	COG1959	2 iron, 2 sulfur cluster binding
EXW31_RS21815	COG1668	transmembrane transport
EXW31_RS21820	COG4152	abc transporter atp-binding protein
EXW31_RS21825	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW31_RS21830	COG1360	Flagellar Motor Protein
EXW31_RS21835	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW31_RS21840	COG1876	peptidase activity
EXW31_RS21845	COG0824	Thioesterase
EXW31_RS21850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW31_RS21855	COG1053	succinate dehydrogenase
EXW31_RS21860	COG2009	succinate dehydrogenase
EXW31_RS21865	COG1719	4-vinyl reductase, 4VR
EXW31_RS21870	COG0322	excinuclease ABC activity
EXW31_RS21875	COG3118	belongs to the thioredoxin family
EXW31_RS21880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW31_RS21885	COG2086	electron transfer activity
EXW31_RS21890	COG1024	Enoyl-CoA hydratase
EXW31_RS21895	COG1309	transcriptional regulator
EXW31_RS21900	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS21925	COG2318	DinB family
EXW31_RS21955	COG1131	(ABC) transporter
EXW31_RS21960	COG2205	protein histidine kinase activity
EXW31_RS21965	COG0745	RESPONSE REGULATOR receiver
EXW31_RS21975	COG4895	conserved protein (DUF2196)
EXW31_RS21980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW31_RS21990	COG4509	Sortase family
EXW31_RS21995	COG1120	ATPase activity
EXW31_RS22010	COG5386	Cell surface protein
EXW31_RS22020	COG5386	Cell surface protein
EXW31_RS22025	COG1114	Component of the transport system for branched-chain amino acids
EXW31_RS22030	COG1187	pseudouridine synthase activity
EXW31_RS22035	COG1193	negative regulation of DNA recombination
EXW31_RS22040	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW31_RS22040	COG1796	DNA polymerase
EXW31_RS22045	COG1286	toxin biosynthetic process
EXW31_RS22050	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW31_RS22055	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW31_RS22080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW31_RS22085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW31_RS22095	COG1418	mRNA catabolic process
EXW31_RS22115	COG2814	Major facilitator Superfamily
EXW31_RS22120	COG1566	PFAM secretion protein HlyD family protein
EXW31_RS22125	COG1309	transcriptional regulator
EXW31_RS22130	COG1363	Peptidase, m42
EXW31_RS22140	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW31_RS22155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW31_RS22165	COG1484	DNA-dependent DNA replication
EXW31_RS22170	COG3611	Membrane attachment protein
EXW31_RS22175	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW31_RS22180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW31_RS22185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW31_RS22195	COG1971	Probably functions as a manganese efflux pump
EXW31_RS22205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW31_RS22205	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW31_RS22210	COG5002	protein histidine kinase activity
EXW31_RS22215	COG0745	RESPONSE REGULATOR receiver
EXW31_RS22235	COG0538	isocitrate dehydrogenase activity
EXW31_RS22240	COG0372	Belongs to the citrate synthase family
EXW31_RS22250	COG0628	permease
EXW31_RS22255	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW31_RS22265	COG0205	6-phosphofructokinase activity
EXW31_RS22280	COG1725	Transcriptional regulator
EXW31_RS22285	COG0281	malic enzyme
EXW31_RS22290	COG0587	DNA-directed DNA polymerase activity
EXW31_RS22305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW31_RS22320	COG4109	DRTGG domain
EXW31_RS22330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW31_RS22335	COG0006	proline dipeptidase activity
EXW31_RS22375	COG1476	TRANSCRIPTIONal
EXW31_RS22390	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS22395	COG0589	response to stress
EXW31_RS22415	COG0165	Argininosuccinate lyase
EXW31_RS22420	COG0137	argininosuccinate synthase activity
EXW31_RS22435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS22450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW31_RS22455	COG0827	DNA restriction-modification system
EXW31_RS22460	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW31_RS22465	COG3874	Sporulation protein YtfJ
EXW31_RS22480	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW31_RS22490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW31_RS22505	COG1104	cysteine desulfurase activity
EXW31_RS22510	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW31_RS22525	COG1309	transcriptional regulator
EXW31_RS22530	COG1956	GAF domain-containing protein
EXW31_RS22535	COG0626	cystathionine gamma-synthase activity
EXW31_RS22540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW31_RS22565	COG1595	DNA-templated transcription, initiation
EXW31_RS22575	COG0110	maltose O-acetyltransferase activity
EXW31_RS22580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW31_RS22585	COG0454	-acetyltransferase
EXW31_RS22590	COG0517	IMP dehydrogenase activity
EXW31_RS22595	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW31_RS22610	COG0745	RESPONSE REGULATOR receiver
EXW31_RS22615	COG5002	protein histidine kinase activity
EXW31_RS22620	COG0666	response to abiotic stimulus
EXW31_RS22630	COG1970	mechanosensitive ion channel activity
EXW31_RS22650	COG1609	Transcriptional regulator
EXW31_RS22655	COG4851	CamS sex pheromone cAM373 precursor
EXW31_RS22660	COG3118	belongs to the thioredoxin family
EXW31_RS22670	COG2309	aminopeptidase activity
EXW31_RS22690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS22695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW31_RS22705	COG1674	ftsk spoiiie
EXW31_RS22720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW31_RS22725	COG4848	Belongs to the UPF0354 family
EXW31_RS22730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW31_RS22735	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW31_RS22740	COG1363	Peptidase, m42
EXW31_RS22750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS22755	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW31_RS22765	COG0510	thiamine kinase activity
EXW31_RS22770	COG1523	belongs to the glycosyl hydrolase 13 family
EXW31_RS22780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW31_RS22785	COG1349	DNA-binding transcription factor activity
EXW31_RS22790	COG1187	pseudouridine synthase activity
EXW31_RS22795	COG2244	polysaccharide biosynthetic process
EXW31_RS22800	COG2081	HI0933 family
EXW31_RS22805	COG2814	Major facilitator Superfamily
EXW31_RS22815	COG3832	glyoxalase III activity
EXW31_RS22835	COG1329	Transcriptional regulator
EXW31_RS22850	COG0314	molybdopterin synthase activity
EXW31_RS22855	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW31_RS22860	COG0303	'Molybdopterin
EXW31_RS22865	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW31_RS22870	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW31_RS22875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW31_RS22895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW31_RS22905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW31_RS22945	COG0495	leucyl-tRNA aminoacylation
EXW31_RS22950	COG2814	Major facilitator Superfamily
EXW31_RS22955	COG0475	glutathione-regulated potassium exporter activity
EXW31_RS22960	COG0490	domain, Protein
EXW31_RS22965	COG0582	viral genome integration into host DNA
EXW31_RS22975	COG1136	(ABC) transporter
EXW31_RS22990	COG1242	4 iron, 4 sulfur cluster binding
EXW31_RS22995	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW31_RS23000	COG1794	racemase activity, acting on amino acids and derivatives
EXW31_RS23020	COG2267	carboxylic ester hydrolase activity
EXW31_RS23025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW31_RS23030	COG0671	phosphoesterase, PA-phosphatase related
EXW31_RS23035	COG0438	transferase activity, transferring glycosyl groups
EXW31_RS23045	COG1404	Belongs to the peptidase S8 family
EXW31_RS23050	COG2197	response regulator
EXW31_RS23055	COG4585	Histidine kinase
EXW31_RS23060	COG0746	molybdenum cofactor guanylyltransferase activity
EXW31_RS23075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW31_RS23080	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW31_RS23110	COG5002	protein histidine kinase activity
EXW31_RS23115	COG3852	Histidine kinase
EXW31_RS23120	COG0753	catalase activity
EXW31_RS23125	COG2267	carboxylic ester hydrolase activity
EXW31_RS23130	COG1368	sulfuric ester hydrolase activity
EXW31_RS23135	COG4895	conserved protein (DUF2196)
EXW31_RS23150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW31_RS23155	COG1116	anion transmembrane transporter activity
EXW31_RS23160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW31_RS23185	COG0494	nUDIX hydrolase
EXW31_RS23225	COG1854	S-ribosylhomocysteine lyase activity
EXW31_RS23235	COG0288	reversible hydration of carbon dioxide
EXW31_RS23240	COG1271	oxidase subunit
EXW31_RS23245	COG1294	oxidase, subunit
EXW31_RS23260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS23285	COG1842	Phage shock protein A
EXW31_RS23310	COG3859	Proton-coupled thiamine transporter YuaJ
EXW31_RS23315	COG5002	protein histidine kinase activity
EXW31_RS23320	COG0745	RESPONSE REGULATOR receiver
EXW31_RS23345	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW31_RS23350	COG1597	lipid kinase activity
EXW31_RS23380	COG1136	(ABC) transporter
EXW31_RS23400	COG5002	protein histidine kinase activity
EXW31_RS23420	COG0577	efflux transmembrane transporter activity
EXW31_RS23425	COG1136	(ABC) transporter
EXW31_RS23430	COG3708	Transcriptional regulator
EXW31_RS23430	COG2207	Transcriptional regulator
EXW31_RS23440	COG1131	(ABC) transporter
EXW31_RS23450	COG5658	integral membrane protein
EXW31_RS23455	COG0640	Transcriptional regulator
EXW31_RS23460	COG0745	RESPONSE REGULATOR receiver
EXW31_RS23465	COG2205	protein histidine kinase activity
EXW31_RS23470	COG0577	efflux transmembrane transporter activity
EXW31_RS23475	COG0577	efflux transmembrane transporter activity
EXW31_RS23480	COG1136	(ABC) transporter
EXW31_RS23485	COG0577	efflux transmembrane transporter activity
EXW31_RS23500	COG2188	Transcriptional regulator
EXW31_RS23520	COG3964	amidohydrolase
EXW31_RS23540	COG4948	Mandelate Racemase Muconate Lactonizing
EXW31_RS23545	COG0318	PFAM AMP-dependent synthetase and ligase
EXW31_RS23550	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW31_RS23555	COG0596	Alpha beta hydrolase
EXW31_RS23560	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW31_RS23565	COG1169	isochorismate synthase
EXW31_RS23570	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW31_RS23575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW31_RS23580	COG1278	Cold shock
EXW31_RS23590	COG1051	belongs to the nudix hydrolase family
EXW31_RS23600	COG0058	SHG alpha-glucan phosphorylase activity
EXW31_RS23610	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW31_RS23615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW31_RS23620	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW31_RS23755	COG1285	pathogenesis
EXW31_RS23760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW31_RS23770	COG0166	Belongs to the GPI family
EXW31_RS23775	COG2155	Conserved Protein
EXW31_RS23780	COG1098	S1 RNA binding domain
EXW31_RS23785	COG0436	Aminotransferase
EXW31_RS23790	COG1522	sequence-specific DNA binding
EXW31_RS23795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW31_RS23800	COG2267	carboxylic ester hydrolase activity
EXW31_RS23810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW31_RS23840	COG5018	Exonuclease
EXW31_RS23845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW31_RS23865	COG2050	protein possibly involved in aromatic compounds catabolism
EXW31_RS23875	COG1268	BioY protein
EXW31_RS23880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW31_RS23885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW31_RS23895	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW31_RS23900	COG3584	3D domain protein
EXW31_RS23915	COG1252	NADH dehydrogenase
EXW31_RS23920	COG0492	ferredoxin-NADP+ reductase activity
EXW31_RS23925	COG3708	Transcriptional regulator
EXW31_RS23940	COG1683	Conserved Protein
EXW31_RS23950	COG0316	Belongs to the HesB IscA family
EXW31_RS23955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW31_RS23960	COG4844	belongs to the
EXW31_RS23965	COG1252	NADH dehydrogenase
EXW31_RS23970	COG2274	protein secretion by the type I secretion system
EXW31_RS23975	COG0390	transport system, permease component
EXW31_RS23980	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW31_RS24020	COG4837	Protein of unknown function (DUF1462)
EXW31_RS24025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW31_RS24035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW31_RS24040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW31_RS24055	COG1136	(ABC) transporter
EXW31_RS24055	COG0577	efflux transmembrane transporter activity
EXW31_RS24060	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS24070	COG0647	UMP catabolic process
EXW31_RS24080	COG2445	Protein of unknown function DUF86
EXW31_RS24085	COG1494	fructose-1,6-bisphosphatase
EXW31_RS24105	COG4470	Protein conserved in bacteria
EXW31_RS24115	COG0789	Transcriptional regulator
EXW31_RS24120	COG4377	Putative membrane peptidase family (DUF2324)
EXW31_RS24145	COG0739	heme binding
EXW31_RS24155	COG3377	Domain of unknown function (DUF1805)
EXW31_RS24160	COG0737	Belongs to the 5'-nucleotidase family
EXW31_RS24165	COG0719	Fe-S assembly protein
EXW31_RS24170	COG0822	iron-sulfur transferase activity
EXW31_RS24175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW31_RS24180	COG0719	Fe-S assembly protein
EXW31_RS24185	COG0396	ATPase activity
EXW31_RS24190	COG1464	Belongs to the NlpA lipoprotein family
EXW31_RS24195	COG1464	Belongs to the NlpA lipoprotein family
EXW31_RS24200	COG2011	ABC-type metal ion transport system permease component
EXW31_RS24215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW31_RS24220	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW31_RS24225	COG0509	glycine decarboxylation via glycine cleavage system
EXW31_RS24230	COG1393	Belongs to the ArsC family
EXW31_RS24265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS24280	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS24285	COG0183	Belongs to the thiolase family
EXW31_RS24290	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW31_RS24290	COG1024	Enoyl-CoA hydratase
EXW31_RS24300	COG1686	Belongs to the peptidase S11 family
EXW31_RS24305	COG0506	proline dehydrogenase activity
EXW31_RS24315	COG0011	TIGRFAM Protein of
EXW31_RS24320	COG0840	transmembrane signaling receptor activity
EXW31_RS24335	COG2814	Major facilitator Superfamily
EXW31_RS24340	COG0531	amino acid
EXW31_RS24360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW31_RS24390	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS24400	COG1376	ErfK ybiS ycfS ynhG family protein
EXW31_RS24405	COG0745	RESPONSE REGULATOR receiver
EXW31_RS24410	COG5002	protein histidine kinase activity
EXW31_RS24420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW31_RS24430	COG0840	transmembrane signaling receptor activity
EXW31_RS24435	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW31_RS24440	COG3227	Zinc metalloprotease (Elastase)
EXW31_RS24445	COG1741	Belongs to the pirin family
EXW31_RS24460	COG0586	Pfam SNARE associated Golgi protein
EXW31_RS24465	COG0475	glutathione-regulated potassium exporter activity
EXW31_RS24470	COG0490	domain, Protein
EXW31_RS24475	COG1115	amino acid carrier protein
EXW31_RS24480	COG0783	Belongs to the Dps family
EXW31_RS24490	COG2318	DinB family
EXW31_RS24495	COG1611	Belongs to the LOG family
EXW31_RS24505	COG1528	Iron-storage protein
EXW31_RS24510	COG2311	Membrane
EXW31_RS24515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS24520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS24525	COG1115	amino acid carrier protein
EXW31_RS24530	COG2910	NAD(P)H-binding
EXW31_RS24540	COG0656	L-ascorbic acid biosynthetic process
EXW31_RS24545	COG2814	Major facilitator Superfamily
EXW31_RS24550	COG1733	regulation of RNA biosynthetic process
EXW31_RS24560	COG1252	NADH dehydrogenase
EXW31_RS24605	COG3655	Transcriptional regulator
EXW31_RS24620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW31_RS24630	COG1733	regulation of RNA biosynthetic process
EXW31_RS24635	COG1522	sequence-specific DNA binding
EXW31_RS24640	COG0288	reversible hydration of carbon dioxide
EXW31_RS24645	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW31_RS24650	COG2233	PERMEase
EXW31_RS24675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS24695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW31_RS24700	COG0557	exoribonuclease II activity
EXW31_RS24705	COG1647	Serine aminopeptidase, S33
EXW31_RS24710	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW31_RS24715	COG1346	cytolysis
EXW31_RS24740	COG0149	triose-phosphate isomerase activity
EXW31_RS24745	COG0126	phosphoglycerate kinase activity
EXW31_RS24750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW31_RS24765	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW31_RS24790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW31_RS24805	COG2323	membrane
EXW31_RS24815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW31_RS24820	COG1481	regulation of sporulation
EXW31_RS24825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW31_RS24830	COG1660	Displays ATPase and GTPase activities
EXW31_RS24835	COG1051	belongs to the nudix hydrolase family
EXW31_RS24845	COG0492	ferredoxin-NADP+ reductase activity
EXW31_RS24850	COG0457	Tetratricopeptide repeat
EXW31_RS24855	COG0110	maltose O-acetyltransferase activity
EXW31_RS24860	COG0546	phosphoglycolate phosphatase activity
EXW31_RS24865	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW31_RS24870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW31_RS24875	COG1950	PFAM Membrane protein of
EXW31_RS24885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW31_RS24900	COG0789	Transcriptional regulator
EXW31_RS24935	COG0583	DNA-binding transcription factor activity
EXW31_RS24940	COG0789	Transcriptional regulator
EXW31_RS24945	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS24950	COG0488	(ABC) transporter
EXW31_RS24960	COG1132	(ABC) transporter
EXW31_RS24965	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW31_RS24970	COG0583	DNA-binding transcription factor activity
EXW31_RS24975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW31_RS24980	COG0793	Belongs to the peptidase S41A family
EXW31_RS24980	COG3409	Peptidoglycan-binding domain 1 protein
EXW31_RS24985	COG2177	Part of the ABC transporter FtsEX involved in
EXW31_RS24990	COG2884	Cell division ATP-binding protein ftsE
EXW31_RS25025	COG1278	Cold shock
EXW31_RS25030	COG1040	competence protein
EXW31_RS25035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW31_RS25040	COG1388	LysM domain
EXW31_RS25040	COG0791	NLP P60 protein
EXW31_RS25045	COG1733	regulation of RNA biosynthetic process
EXW31_RS25050	COG1307	EDD domain protein, DegV family
EXW31_RS25055	COG1739	Uncharacterized protein family UPF0029
EXW31_RS25060	COG1316	TRANSCRIPTIONal
EXW31_RS25065	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW31_RS25070	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW31_RS25075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW31_RS25085	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW31_RS25085	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW31_RS25105	COG1486	melibiose metabolic process
EXW31_RS25110	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW31_RS25115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS25125	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW31_RS25135	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW31_RS25145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW31_RS25150	COG1301	dicarboxylic acid transport
EXW31_RS25165	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW31_RS25175	COG1271	oxidase subunit
EXW31_RS25180	COG1294	oxidase, subunit
EXW31_RS25185	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW31_RS25190	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW31_RS25195	COG1620	l-lactate permease
EXW31_RS25205	COG2389	metal-binding protein
EXW31_RS25215	COG1368	sulfuric ester hydrolase activity
EXW31_RS25225	COG0791	NLP P60 protein
EXW31_RS25225	COG1388	LysM domain
EXW31_RS25230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW31_RS25240	COG1215	transferase activity, transferring glycosyl groups
EXW31_RS25245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW31_RS25250	COG3584	3D domain protein
EXW31_RS25250	COG1388	LysM domain
EXW31_RS25260	COG4715	Zinc finger, swim domain protein
EXW31_RS25265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW31_RS25310	COG0577	efflux transmembrane transporter activity
EXW31_RS25315	COG1136	(ABC) transporter
EXW31_RS25345	COG0745	RESPONSE REGULATOR receiver
EXW31_RS25350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW31_RS25365	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW31_RS25380	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW31_RS25395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW31_RS25415	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW31_RS25420	COG1134	teichoic acid transport
EXW31_RS25425	COG1682	transport, permease protein
EXW31_RS25430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW31_RS25470	COG1609	Transcriptional regulator
EXW31_RS25475	COG2801	Transposase and inactivated derivatives
EXW31_RS25490	COG0739	heme binding
EXW31_RS25505	COG4555	ABC transporter
EXW31_RS25510	COG2385	sporulation resulting in formation of a cellular spore
EXW31_RS25525	COG4836	Membrane
EXW31_RS25530	COG1007	ATP synthesis coupled electron transport
EXW31_RS25535	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW31_RS25540	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW31_RS25545	COG0713	ATP synthesis coupled electron transport
EXW31_RS25550	COG0839	Belongs to the complex I subunit 6 family
EXW31_RS25560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW31_RS25565	COG0649	NAD binding
EXW31_RS25570	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW31_RS25575	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW31_RS25580	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW31_RS25585	COG5001	Diguanylate cyclase
EXW31_RS25585	COG3300	MHYT domain
EXW31_RS25600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW31_RS25605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW31_RS25610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW31_RS25615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW31_RS25625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW31_RS25635	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW31_RS25670	COG0698	ribose 5-phosphate isomerase
EXW31_RS25680	COG2190	(PTS) system
EXW31_RS25685	COG2259	Doxx family
EXW31_RS25690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW31_RS25700	COG1971	Probably functions as a manganese efflux pump
EXW31_RS25705	COG0009	L-threonylcarbamoyladenylate synthase
EXW31_RS25720	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW31_RS25725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW31_RS25730	COG1435	thymidine kinase activity
EXW31_RS25740	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW31_RS25745	COG1494	fructose-1,6-bisphosphatase
EXW31_RS25765	COG4821	SIS domain
EXW31_RS25770	COG0504	CTP synthase activity
EXW31_RS25785	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS25790	COG1960	acyl-CoA dehydrogenase activity
EXW31_RS25795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW31_RS25800	COG0183	Belongs to the thiolase family
EXW31_RS25805	COG2181	nitrate reductase activity
EXW31_RS25805	COG0247	lactate metabolic process
EXW31_RS25810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW31_RS25815	COG4294	response to UV
EXW31_RS25820	COG3300	MHYT domain
EXW31_RS25820	COG5001	Diguanylate cyclase
EXW31_RS25835	COG3227	Zinc metalloprotease (Elastase)
EXW31_RS25840	COG2197	response regulator
EXW31_RS25845	COG4585	Histidine kinase
EXW31_RS25850	COG0842	Transport permease protein
EXW31_RS25855	COG1131	(ABC) transporter
EXW31_RS25860	COG0024	Methionine aminopeptidase
EXW31_RS25865	COG2234	aminopeptidase activity
EXW31_RS25900	COG4506	Protein conserved in bacteria
EXW31_RS25905	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW31_RS25930	COG2814	Major facilitator Superfamily
EXW31_RS25935	COG0789	Transcriptional regulator
EXW31_RS25940	COG0584	glycerophosphoryl diester phosphodiesterase
EXW31_RS25945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW31_RS25955	COG1994	Peptidase M50
EXW31_RS25965	COG1078	dGTPase activity
EXW31_RS25970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW31_RS25975	COG1120	ATPase activity
EXW31_RS25980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS25985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW31_RS25990	COG4844	belongs to the
EXW31_RS26010	COG0280	phosphate acetyltransferase
EXW31_RS26015	COG3253	May function as heme-dependent peroxidase
EXW31_RS26025	COG3773	Cell wall hydrolase
EXW31_RS26035	COG2363	Small membrane protein
EXW31_RS26045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW31_RS26050	COG2233	PERMEase
EXW31_RS26055	COG0561	phosphatase activity
EXW31_RS26060	COG2814	Major facilitator Superfamily
EXW31_RS26065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW31_RS26070	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW31_RS26075	COG1131	(ABC) transporter
EXW31_RS26080	COG2755	lipolytic protein G-D-S-L family
EXW31_RS26085	COG1609	Transcriptional regulator
EXW31_RS26095	COG0460	homoserine dehydrogenase
EXW31_RS26100	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW31_RS26105	COG2873	o-acetylhomoserine
EXW31_RS26120	COG2197	response regulator
EXW31_RS26125	COG2203	Gaf domain
EXW31_RS26125	COG4585	Histidine kinase
EXW31_RS26130	COG0351	phosphomethylpyrimidine kinase
EXW31_RS26135	COG3706	GGDEF domain
EXW31_RS26140	COG2879	small protein
EXW31_RS26145	COG1966	Carbon starvation protein
EXW31_RS26150	COG3279	Response regulator of the LytR AlgR family
EXW31_RS26155	COG0477	Major facilitator Superfamily
EXW31_RS26180	COG0840	transmembrane signaling receptor activity
EXW31_RS26190	COG1607	acyl-coa hydrolase
EXW31_RS26200	COG1216	Glycosyl transferase, family 2
EXW31_RS26205	COG0488	(ABC) transporter
EXW31_RS26220	COG0463	Glycosyl transferase, family 2
EXW31_RS26225	COG1309	transcriptional regulator
EXW31_RS26230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW31_RS26235	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW31_RS26235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW31_RS26240	COG0628	permease
EXW31_RS26250	COG1380	Effector of murein hydrolase LrgA
EXW31_RS26255	COG3279	Response regulator of the LytR AlgR family
EXW31_RS26260	COG3275	phosphorelay sensor kinase activity
EXW31_RS26265	COG2814	Major facilitator Superfamily
EXW31_RS26270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW31_RS26275	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW31_RS26320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW31_RS26325	COG1272	protein, Hemolysin III
EXW31_RS26350	COG1164	Oligoendopeptidase f
EXW31_RS26365	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW31_RS26375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW31_RS26380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW31_RS26385	COG4853	Protein conserved in bacteria
EXW31_RS26395	COG5002	protein histidine kinase activity
EXW31_RS26400	COG0745	RESPONSE REGULATOR receiver
EXW31_RS26430	COG0305	Participates in initiation and elongation during chromosome replication
EXW31_RS26440	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW31_RS26445	COG4241	membrane
EXW31_RS26455	COG0629	single-stranded DNA binding
EXW31_RS26460	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW31_RS26465	COG0012	GTP binding
EXW31_RS26470	COG4481	Protein conserved in bacteria
EXW31_RS26475	COG0668	transmembrane transport
EXW31_RS26485	COG1475	DNA binding
EXW31_RS26490	COG1192	Involved in chromosome partitioning
EXW31_RS26495	COG1475	DNA binding
EXW31_RS26505	COG0445	tRNA wobble uridine modification
EXW31_RS26510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW31_RS26515	COG1847	R3H domain protein
EXW31_RS26520	COG0706	membrane insertase activity
EXW31_RS26525	COG0594	ribonuclease P activity
EXW31_RS26530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW31_RS26580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW31_RS26605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW31_RS26640	COG0561	phosphatase activity
EXW31_RS26650	COG1609	Transcriptional regulator
EXW31_RS26680	COG0494	nUDIX hydrolase
EXW31_RS26705	COG0739	heme binding
EXW31_RS26715	COG1595	DNA-templated transcription, initiation
EXW31_RS26735	COG2409	Drug exporters of the RND superfamily
EXW31_RS26810	COG0456	acetyltransferase
EXW31_RS26875	COG1278	Cold shock
EXW31_RS26895	COG0582	viral genome integration into host DNA
EXW31_RS26905	COG5566	PFAM Mor transcription activator
EXW31_RS26910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW31_RS26950	COG0531	amino acid
EXW31_RS26955	COG3338	carbonate dehydratase activity
EXW31_RS26965	COG5002	protein histidine kinase activity
EXW31_RS26995	COG5002	protein histidine kinase activity
EXW31_RS27010	COG0583	DNA-binding transcription factor activity
EXW31_RS27015	COG1741	Belongs to the pirin family
EXW31_RS27020	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW31_RS27025	COG3227	Zinc metalloprotease (Elastase)
EXW31_RS27055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW31_RS27065	COG2707	UPF0756 membrane protein
EXW31_RS27075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW31_RS27080	COG4974	Belongs to the 'phage' integrase family
EXW31_RS27095	COG0583	DNA-binding transcription factor activity
EXW31_RS27100	COG4689	acetoacetate decarboxylase
EXW31_RS27120	COG0531	amino acid
EXW31_RS27130	COG2318	DinB family
EXW31_RS27135	COG2378	regulation of single-species biofilm formation
EXW31_RS27155	COG1309	transcriptional regulator
EXW31_RS27185	COG3739	integral membrane protein
EXW31_RS27190	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW31_RS27195	COG1131	(ABC) transporter
EXW31_RS27205	COG3655	Transcriptional regulator
EXW31_RS27240	COG1131	(ABC) transporter
EXW31_RS27260	COG0825	malonyl-CoA metabolic process
EXW31_RS27300	COG2814	Major facilitator Superfamily
EXW31_RS27305	COG0583	DNA-binding transcription factor activity
EXW31_RS27370	COG3493	citrate carrier protein
EXW31_RS27375	COG4565	transcriptional regulatory protein
EXW31_RS27380	COG3290	protein histidine kinase activity
EXW31_RS27420	COG0753	catalase activity
EXW31_RS27565	COG1192	Involved in chromosome partitioning
EXW31_RS27645	COG3344	reverse transcriptase
EXW31_RS27675	COG3344	reverse transcriptase
EXW31_RS27680	COG0741	lytic transglycosylase activity
EXW31_RS27680	COG0791	NLP P60 protein
EXW31_RS27730	COG4152	abc transporter atp-binding protein
EXW31_RS27735	COG1668	transmembrane transport
EXW31_RS27790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW31_RS27850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW31_RS27850	COG2755	lipolytic protein G-D-S-L family
EXW31_RS27890	COG0741	lytic transglycosylase activity
EXW31_RS27950	COG1131	(ABC) transporter
EXW31_RS27970	COG0457	Tetratricopeptide repeat
EXW31_RS28060	COG1401	restriction endodeoxyribonuclease activity
EXW31_RS28165	COG2003	Belongs to the UPF0758 family
EXW31_RS28175	COG1609	Transcriptional regulator
EXW31_RS28180	COG2814	Major facilitator Superfamily
EXW31_RS28185	COG0673	inositol 2-dehydrogenase activity
EXW31_RS28215	COG3718	enzyme involved in inositol metabolism
EXW31_RS28255	COG0693	protein deglycase activity
EXW31_RS28280	COG0659	secondary active sulfate transmembrane transporter activity
EXW31_RS28295	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW31_RS28340	COG2188	Transcriptional regulator
EXW31_RS28355	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW31_RS28355	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW31_RS28360	COG3715	PTS system
EXW31_RS28435	COG5002	protein histidine kinase activity
EXW31_RS28515	COG1819	glycosyl
EXW31_RS28520	COG0156	8-amino-7-oxononanoate synthase activity
EXW31_RS28525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW31_RS28530	COG1136	(ABC) transporter
EXW31_RS28565	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW31_RS28590	COG0577	efflux transmembrane transporter activity
EXW31_RS28595	COG1136	(ABC) transporter
EXW31_RS28610	COG1396	sequence-specific DNA binding
EXW31_RS28615	COG0006	proline dipeptidase activity
EXW31_RS28625	COG0457	Tetratricopeptide repeat
EXW31_RS28690	COG1073	alpha beta
EXW31_RS28715	COG1876	peptidase activity
EXW31_RS28745	COG4974	Belongs to the 'phage' integrase family
EXW31_RS28790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW31_RS28800	COG0814	amino acid
EXW31_RS28805	COG1760	l-serine dehydratase
EXW31_RS28810	COG1760	l-serine dehydratase
EXW31_RS28815	COG1476	TRANSCRIPTIONal
EXW31_RS28825	COG2720	vancomycin resistance protein
EXW31_RS28845	COG1073	alpha beta
EXW31_RS28860	COG2318	DinB family
EXW31_RS28880	COG1309	transcriptional regulator
EXW31_RS28935	COG2205	protein histidine kinase activity
EXW31_RS28940	COG0745	RESPONSE REGULATOR receiver
EXW31_RS29050	COG2508	Transcriptional regulator
EXW31_RS29050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW31_RS29070	COG2814	Major facilitator Superfamily
EXW31_RS29075	COG1309	transcriptional regulator
EXW31_RS29085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW31_RS29110	COG1329	Transcriptional regulator
EXW31_RS29135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW31_RS29140	COG1011	Hydrolase
EXW31_RS29165	COG1028	Short-chain dehydrogenase reductase Sdr
EXW31_RS29185	COG0814	amino acid
EXW31_RS29190	COG0697	spore germination
EXW31_RS29335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW31_RS29615	COG1671	Belongs to the UPF0178 family
EXW31_RS29620	COG1671	Belongs to the UPF0178 family