locus-tag	class	description
EXW26_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW26_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW26_RS00015	COG2501	S4 domain
EXW26_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW26_RS00025	COG0187	DNA topoisomerase II activity
EXW26_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW26_RS00065	COG0516	GMP reductase activity
EXW26_RS00065	COG0517	IMP dehydrogenase activity
EXW26_RS00070	COG1686	Belongs to the peptidase S11 family
EXW26_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW26_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW26_RS00100	COG1428	Deoxynucleoside kinase
EXW26_RS00105	COG1428	Deoxynucleoside kinase
EXW26_RS00110	COG1335	isochorismatase
EXW26_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW26_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW26_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW26_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW26_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW26_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW26_RS00190	COG0470	DNA polymerase III
EXW26_RS00195	COG1774	PSP1 C-terminal conserved region
EXW26_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW26_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW26_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW26_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW26_RS00230	COG0084	hydrolase, TatD family'
EXW26_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW26_RS00250	COG4466	Protein conserved in bacteria
EXW26_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW26_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW26_RS00270	COG0251	oxidation-reduction process
EXW26_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW26_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW26_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW26_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW26_RS00310	COG2244	polysaccharide biosynthetic process
EXW26_RS00315	COG3956	TIGRFAM MazG family protein
EXW26_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW26_RS00340	COG1098	S1 RNA binding domain
EXW26_RS00355	COG2208	phosphoserine phosphatase activity
EXW26_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW26_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW26_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW26_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW26_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW26_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW26_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW26_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW26_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW26_RS00420	COG1396	sequence-specific DNA binding
EXW26_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW26_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW26_RS00515	COG3880	PFAM UvrB UvrC protein
EXW26_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW26_RS00525	COG0542	response to heat
EXW26_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW26_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW26_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW26_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW26_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW26_RS00560	COG1045	serine acetyltransferase
EXW26_RS00565	COG0215	cysteine-tRNA ligase activity
EXW26_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW26_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW26_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW26_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW26_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW26_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW26_RS00610	COG0081	regulation of translation
EXW26_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW26_RS00620	COG0222	ribosome binding
EXW26_RS00625	COG2813	Specifically methylates the guanine in position
EXW26_RS00630	COG0085	RNA polymerase activity
EXW26_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW26_RS00640	COG1358	cellular component organization or biogenesis
EXW26_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW26_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW26_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW26_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW26_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW26_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW26_RS00680	COG0089	rRNA binding
EXW26_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW26_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW26_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW26_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW26_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW26_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW26_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW26_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW26_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW26_RS00760	COG1841	ribosomal large subunit assembly
EXW26_RS00765	COG0200	Binds to the 23S rRNA
EXW26_RS00770	COG0201	protein transport
EXW26_RS00775	COG0563	adenylate kinase activity
EXW26_RS00780	COG0024	Methionine aminopeptidase
EXW26_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW26_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW26_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW26_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW26_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW26_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW26_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS00855	COG0489	protein tyrosine kinase activity
EXW26_RS00865	COG2194	sulfuric ester hydrolase activity
EXW26_RS00870	COG0726	polysaccharide deacetylase
EXW26_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW26_RS00955	COG4856	YbbR-like protein
EXW26_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW26_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS01010	COG2011	ABC-type metal ion transport system permease component
EXW26_RS01020	COG1464	Belongs to the NlpA lipoprotein family
EXW26_RS01035	COG0277	FAD linked oxidase domain protein
EXW26_RS01040	COG2271	Major facilitator Superfamily
EXW26_RS01050	COG2814	Major facilitator Superfamily
EXW26_RS01070	COG0601	transmembrane transport
EXW26_RS01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_RS01080	COG0444	Belongs to the ABC transporter superfamily
EXW26_RS01085	COG4608	Belongs to the ABC transporter superfamily
EXW26_RS01090	COG4166	transmembrane transport
EXW26_RS01100	COG2207	Transcriptional regulator
EXW26_RS01115	COG4166	transmembrane transport
EXW26_RS01120	COG4166	transmembrane transport
EXW26_RS01125	COG0656	L-ascorbic acid biosynthetic process
EXW26_RS01130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_RS01145	COG4149	molybdate abc transporter
EXW26_RS01150	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW26_RS01155	COG1910	domain protein
EXW26_RS01170	COG0697	spore germination
EXW26_RS01185	COG0204	Acyl-transferase
EXW26_RS01195	COG1609	Transcriptional regulator
EXW26_RS01205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS01220	COG5298	Protein conserved in bacteria
EXW26_RS01240	COG0488	(ABC) transporter
EXW26_RS01250	COG0747	negative chemotaxis
EXW26_RS01260	COG0601	transmembrane transport
EXW26_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_RS01270	COG0444	Belongs to the ABC transporter superfamily
EXW26_RS01275	COG4608	Belongs to the ABC transporter superfamily
EXW26_RS01280	COG0561	phosphatase activity
EXW26_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW26_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW26_RS01325	COG0531	amino acid
EXW26_RS01330	COG2814	Major facilitator Superfamily
EXW26_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW26_RS01350	COG4294	response to UV
EXW26_RS01355	COG0705	Rhomboid family
EXW26_RS01360	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW26_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW26_RS01370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_RS01375	COG0864	Transcriptional regulator
EXW26_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW26_RS01385	COG2183	response to ionizing radiation
EXW26_RS01485	COG0802	atpase or kinase
EXW26_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW26_RS01495	COG0456	acetyltransferase
EXW26_RS01505	COG0488	(ABC) transporter
EXW26_RS01510	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW26_RS01520	COG1266	CAAX protease self-immunity
EXW26_RS01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW26_RS01530	COG0459	protein refolding
EXW26_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
EXW26_RS01535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW26_RS01540	COG2252	PERMEase
EXW26_RS01550	COG5002	protein histidine kinase activity
EXW26_RS01575	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW26_RS01595	COG0693	protein deglycase activity
EXW26_RS01645	COG2205	protein histidine kinase activity
EXW26_RS01670	COG0697	spore germination
EXW26_RS01695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW26_RS01700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW26_RS01705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW26_RS01710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW26_RS01715	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW26_RS01720	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW26_RS01725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW26_RS01730	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW26_RS01735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW26_RS01740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW26_RS01745	COG0138	bifunctional purine biosynthesis protein purh
EXW26_RS01750	COG0151	Belongs to the GarS family
EXW26_RS01770	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW26_RS01775	COG0210	DNA helicase
EXW26_RS01780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW26_RS01785	COG4851	CamS sex pheromone cAM373 precursor
EXW26_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS01800	COG1335	isochorismatase
EXW26_RS01810	COG2011	ABC-type metal ion transport system permease component
EXW26_RS01815	COG1464	Belongs to the NlpA lipoprotein family
EXW26_RS01830	COG0003	Pfam Anion-transporting ATPase
EXW26_RS01835	COG1846	Transcriptional regulator
EXW26_RS01840	COG4682	membrane
EXW26_RS01850	COG0154	amidase activity
EXW26_RS01855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW26_RS01860	COG1597	lipid kinase activity
EXW26_RS01865	COG0546	phosphoglycolate phosphatase activity
EXW26_RS01870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW26_RS01880	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS01885	COG2076	Multidrug Resistance protein
EXW26_RS01890	COG2309	aminopeptidase activity
EXW26_RS01905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS01915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW26_RS01920	COG5002	protein histidine kinase activity
EXW26_RS01925	COG4807	Protein conserved in bacteria
EXW26_RS01950	COG1757	Na H antiporter
EXW26_RS01955	COG1473	amidohydrolase
EXW26_RS01975	COG0450	alkyl hydroperoxide reductase
EXW26_RS01985	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW26_RS01995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS02000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS02005	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS02010	COG0492	ferredoxin-NADP+ reductase activity
EXW26_RS02020	COG0166	Belongs to the GPI family
EXW26_RS02045	COG5002	protein histidine kinase activity
EXW26_RS02065	COG3541	Predicted nucleotidyltransferase
EXW26_RS02070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_RS02070	COG0723	plastoquinol--plastocyanin reductase activity
EXW26_RS02080	COG0765	amino acid transport
EXW26_RS02085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS02095	COG0840	transmembrane signaling receptor activity
EXW26_RS02120	COG0549	Belongs to the carbamate kinase family
EXW26_RS02135	COG0277	FAD linked oxidase domain protein
EXW26_RS02140	COG0366	Alpha amylase catalytic
EXW26_RS02145	COG1263	PTS System
EXW26_RS02145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_RS02145	COG2190	(PTS) system
EXW26_RS02165	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW26_RS02175	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW26_RS02195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_RS02200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_RS02205	COG1116	anion transmembrane transporter activity
EXW26_RS02210	COG0488	(ABC) transporter
EXW26_RS02255	COG2270	Major facilitator Superfamily
EXW26_RS02285	COG2310	stress, protein
EXW26_RS02290	COG2310	stress, protein
EXW26_RS02295	COG2310	stress, protein
EXW26_RS02300	COG0861	Integral membrane protein TerC family
EXW26_RS02310	COG3853	Toxic anion resistance protein (TelA)
EXW26_RS02320	COG4840	Belongs to the UPF0435 family
EXW26_RS02325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW26_RS02335	COG1295	ribonuclease BN
EXW26_RS02340	COG2217	Heavy metal translocating P-type atpase
EXW26_RS02345	COG0697	spore germination
EXW26_RS02365	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS02380	COG3871	stress protein (general stress protein 26)
EXW26_RS02385	COG0387	Pfam Sodium calcium exchanger
EXW26_RS02395	COG0535	radical SAM domain protein
EXW26_RS02415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW26_RS02435	COG3829	transcription factor binding
EXW26_RS02445	COG0833	amino acid
EXW26_RS02450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_RS02470	COG2066	Belongs to the glutaminase family
EXW26_RS02475	COG1263	PTS System
EXW26_RS02475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_RS02480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_RS02495	COG1216	Glycosyl transferase, family 2
EXW26_RS02505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_RS02505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW26_RS02510	COG0463	Glycosyl transferase, family 2
EXW26_RS02525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW26_RS02530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW26_RS02545	COG1228	amidohydrolase
EXW26_RS02550	COG1090	epimerase
EXW26_RS02555	COG2137	regulation of response to DNA damage stimulus
EXW26_RS02580	COG1988	membrane-bound metal-dependent
EXW26_RS02585	COG1194	a g-specific adenine glycosylase
EXW26_RS02605	COG3557	Belongs to the UPF0374 family
EXW26_RS02610	COG1132	(ABC) transporter
EXW26_RS02615	COG4129	membrane
EXW26_RS02620	COG0067	glutamate synthase
EXW26_RS02620	COG0069	glutamate synthase activity
EXW26_RS02620	COG0070	glutamate synthase
EXW26_RS02625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW26_RS02630	COG4555	ABC transporter
EXW26_RS02650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW26_RS02655	COG0735	belongs to the Fur family
EXW26_RS02775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW26_RS02780	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW26_RS02800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW26_RS02810	COG2766	serine protein kinase
EXW26_RS02815	COG2718	Belongs to the UPF0229 family
EXW26_RS02830	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW26_RS02835	COG2268	Band 7 protein
EXW26_RS02845	COG3290	protein histidine kinase activity
EXW26_RS02850	COG4565	transcriptional regulatory protein
EXW26_RS02855	COG2851	Citrate transporter
EXW26_RS02880	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW26_RS02885	COG3842	ATPase activity
EXW26_RS02890	COG1175	transmembrane transport
EXW26_RS02895	COG0395	ABC-type sugar transport system, permease component
EXW26_RS02905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW26_RS02910	COG0745	RESPONSE REGULATOR receiver
EXW26_RS02915	COG5002	protein histidine kinase activity
EXW26_RS02925	COG4990	cell redox homeostasis
EXW26_RS02935	COG3290	protein histidine kinase activity
EXW26_RS02940	COG4565	transcriptional regulatory protein
EXW26_RS02945	COG3493	citrate carrier protein
EXW26_RS02950	COG0281	malic enzyme
EXW26_RS02960	COG0697	spore germination
EXW26_RS02965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS02975	COG5002	protein histidine kinase activity
EXW26_RS02980	COG0745	RESPONSE REGULATOR receiver
EXW26_RS02985	COG0456	acetyltransferase
EXW26_RS02990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW26_RS02995	COG3383	formate dehydrogenase (NAD+) activity
EXW26_RS03000	COG2427	Protein of unknown function (DUF1641)
EXW26_RS03015	COG0531	amino acid
EXW26_RS03025	COG0640	Transcriptional regulator
EXW26_RS03030	COG2217	Heavy metal translocating P-type atpase
EXW26_RS03035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW26_RS03050	COG3227	Zinc metalloprotease (Elastase)
EXW26_RS03070	COG2720	vancomycin resistance protein
EXW26_RS03075	COG1316	TRANSCRIPTIONal
EXW26_RS03080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS03085	COG0346	lactoylglutathione lyase activity
EXW26_RS03090	COG1253	flavin adenine dinucleotide binding
EXW26_RS03095	COG1027	Aspartate ammonia-lyase
EXW26_RS03100	COG1620	l-lactate permease
EXW26_RS03105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS03120	COG3104	oligopeptide transport
EXW26_RS03125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS03130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS03150	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_RS03155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_RS03165	COG4548	von Willebrand factor, type A
EXW26_RS03170	COG0714	Associated with various cellular activities
EXW26_RS03190	COG0531	amino acid
EXW26_RS03195	COG2188	Transcriptional regulator
EXW26_RS03200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_RS03200	COG1263	PTS System
EXW26_RS03205	COG0366	Alpha amylase catalytic
EXW26_RS03220	COG0697	spore germination
EXW26_RS03225	COG4585	Histidine kinase
EXW26_RS03230	COG2197	response regulator
EXW26_RS03235	COG1404	Belongs to the peptidase S8 family
EXW26_RS03250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_RS03255	COG1115	amino acid carrier protein
EXW26_RS03260	COG1126	abc transporter atp-binding protein
EXW26_RS03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS03270	COG0765	amino acid transport
EXW26_RS03275	COG0765	amino acid transport
EXW26_RS03280	COG0833	amino acid
EXW26_RS03305	COG2378	regulation of single-species biofilm formation
EXW26_RS03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW26_RS03315	COG5002	protein histidine kinase activity
EXW26_RS03330	COG0659	secondary active sulfate transmembrane transporter activity
EXW26_RS03355	COG0601	transmembrane transport
EXW26_RS03360	COG4608	Belongs to the ABC transporter superfamily
EXW26_RS03370	COG2271	Major facilitator Superfamily
EXW26_RS03375	COG1846	Transcriptional regulator
EXW26_RS03380	COG0477	Major facilitator Superfamily
EXW26_RS03385	COG1609	Transcriptional regulator
EXW26_RS03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW26_RS03395	COG1869	D-ribose catabolic process
EXW26_RS03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW26_RS03410	COG1879	ABC-type sugar transport system periplasmic component
EXW26_RS03440	COG1063	alcohol dehydrogenase
EXW26_RS03485	COG0840	transmembrane signaling receptor activity
EXW26_RS03490	COG3583	domain protein
EXW26_RS03490	COG3584	3D domain protein
EXW26_RS03495	COG1476	TRANSCRIPTIONal
EXW26_RS03515	COG3104	oligopeptide transport
EXW26_RS03520	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS03535	COG1113	amino acid transport
EXW26_RS03540	COG2252	PERMEase
EXW26_RS03545	COG3620	sequence-specific DNA binding
EXW26_RS03565	COG0569	domain protein
EXW26_RS03565	COG0475	glutathione-regulated potassium exporter activity
EXW26_RS03575	COG1845	cytochrome c oxidase, subunit III
EXW26_RS03580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW26_RS03590	COG0833	amino acid
EXW26_RS03595	COG4990	cell redox homeostasis
EXW26_RS03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_RS03615	COG0697	spore germination
EXW26_RS03620	COG0531	amino acid
EXW26_RS03630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW26_RS03635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW26_RS03645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW26_RS03650	COG0573	inorganic phosphate transmembrane transporter activity
EXW26_RS03655	COG0581	inorganic phosphate transmembrane transporter activity
EXW26_RS03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW26_RS03785	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW26_RS03800	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS03800	COG3103	Sh3 type 3 domain protein
EXW26_RS03800	COG4991	sh3 domain protein
EXW26_RS03805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW26_RS03810	COG1116	anion transmembrane transporter activity
EXW26_RS03815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_RS03820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_RS03825	COG0352	thiamine-phosphate diphosphorylase activity
EXW26_RS03830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_RS03835	COG2104	thiamine diphosphate biosynthetic process
EXW26_RS03840	COG2022	thiamine diphosphate biosynthetic process
EXW26_RS03845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_RS03850	COG0351	phosphomethylpyrimidine kinase
EXW26_RS03875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW26_RS03880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW26_RS03885	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW26_RS03890	COG2205	protein histidine kinase activity
EXW26_RS03895	COG2814	Major facilitator Superfamily
EXW26_RS03900	COG1846	Transcriptional regulator
EXW26_RS03920	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW26_RS03925	COG1129	ABC transporter
EXW26_RS03930	COG1879	ABC-type sugar transport system periplasmic component
EXW26_RS03935	COG2252	PERMEase
EXW26_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS04000	COG0778	Nitroreductase
EXW26_RS04005	COG2719	SpoVR family
EXW26_RS04030	COG1937	Protein conserved in bacteria
EXW26_RS04035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS04035	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_RS04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS04040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS04045	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_RS04050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS04050	COG0425	Belongs to the sulfur carrier protein TusA family
EXW26_RS04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS04060	COG2210	Belongs to the sulfur carrier protein TusA family
EXW26_RS04065	COG0730	response to heat
EXW26_RS04075	COG1316	TRANSCRIPTIONal
EXW26_RS04095	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW26_RS04100	COG0604	alcohol dehydrogenase
EXW26_RS04105	COG2814	Major facilitator Superfamily
EXW26_RS04115	COG3711	transcriptional antiterminator
EXW26_RS04115	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_RS04120	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_RS04125	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_RS04150	COG3584	3D domain protein
EXW26_RS04150	COG1388	LysM domain
EXW26_RS04155	COG0577	efflux transmembrane transporter activity
EXW26_RS04160	COG1136	(ABC) transporter
EXW26_RS04170	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW26_RS04185	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS04190	COG3546	catalase activity
EXW26_RS04220	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS04250	COG0531	amino acid
EXW26_RS04255	COG0475	glutathione-regulated potassium exporter activity
EXW26_RS04265	COG1737	Transcriptional regulator
EXW26_RS04275	COG1263	PTS System
EXW26_RS04275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_RS04285	COG2259	Doxx family
EXW26_RS04310	COG1522	sequence-specific DNA binding
EXW26_RS04335	COG2076	Multidrug Resistance protein
EXW26_RS04340	COG1309	transcriptional regulator
EXW26_RS04345	COG2814	Major facilitator Superfamily
EXW26_RS04350	COG1733	regulation of RNA biosynthetic process
EXW26_RS04365	COG4533	DNA binding
EXW26_RS04370	COG2211	Major facilitator Superfamily
EXW26_RS04390	COG0531	amino acid
EXW26_RS04395	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS04400	COG1132	(ABC) transporter
EXW26_RS04405	COG1132	(ABC) transporter
EXW26_RS04410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS04415	COG0765	amino acid transport
EXW26_RS04420	COG1126	abc transporter atp-binding protein
EXW26_RS04435	COG0189	ligase activity
EXW26_RS04445	COG4399	Belongs to the UPF0754 family
EXW26_RS04450	COG3679	Belongs to the UPF0342 family
EXW26_RS04465	COG0028	Belongs to the TPP enzyme family
EXW26_RS04470	COG3527	Alpha-acetolactate decarboxylase
EXW26_RS04475	COG0463	Glycosyl transferase, family 2
EXW26_RS04480	COG1216	Glycosyl transferase, family 2
EXW26_RS04485	COG2094	Belongs to the DNA glycosylase MPG family
EXW26_RS04490	COG0561	phosphatase activity
EXW26_RS04500	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_RS04500	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW26_RS04510	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS04520	COG0659	secondary active sulfate transmembrane transporter activity
EXW26_RS04525	COG2244	polysaccharide biosynthetic process
EXW26_RS04545	COG1024	Enoyl-CoA hydratase
EXW26_RS04565	COG1363	Peptidase, m42
EXW26_RS04580	COG2318	DinB family
EXW26_RS04600	COG0579	oxidoreductase
EXW26_RS04640	COG0601	transmembrane transport
EXW26_RS04645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_RS04650	COG0444	Belongs to the ABC transporter superfamily
EXW26_RS04655	COG4608	Belongs to the ABC transporter superfamily
EXW26_RS04680	COG0477	Major facilitator Superfamily
EXW26_RS04685	COG3290	protein histidine kinase activity
EXW26_RS04690	COG4565	transcriptional regulatory protein
EXW26_RS04695	COG3181	Tripartite tricarboxylate transporter family receptor
EXW26_RS04735	COG0789	Transcriptional regulator
EXW26_RS04735	COG4978	Transcriptional regulator
EXW26_RS04750	COG0305	Participates in initiation and elongation during chromosome replication
EXW26_RS04780	COG1842	Phage shock protein A
EXW26_RS04795	COG0477	Major facilitator Superfamily
EXW26_RS04855	COG2814	Major facilitator Superfamily
EXW26_RS04860	COG0640	Transcriptional regulator
EXW26_RS04880	COG2376	Dihydroxyacetone kinase
EXW26_RS04895	COG2376	Dihydroxyacetone kinase
EXW26_RS04910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_RS04915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_RS04955	COG1959	2 iron, 2 sulfur cluster binding
EXW26_RS04975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_RS04990	COG0457	Tetratricopeptide repeat
EXW26_RS05000	COG2373	Large extracellular alpha-helical protein
EXW26_RS05055	COG0825	malonyl-CoA metabolic process
EXW26_RS05080	COG2807	transmembrane transport
EXW26_RS05085	COG2186	Transcriptional regulator
EXW26_RS05095	COG4585	Histidine kinase
EXW26_RS05100	COG2197	response regulator
EXW26_RS05130	COG0420	3'-5' exonuclease activity
EXW26_RS05135	COG4717	serine-type aminopeptidase activity
EXW26_RS05140	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW26_RS05150	COG0346	lactoylglutathione lyase activity
EXW26_RS05155	COG0346	lactoylglutathione lyase activity
EXW26_RS05160	COG0457	Tetratricopeptide repeat
EXW26_RS05170	COG2267	carboxylic ester hydrolase activity
EXW26_RS05180	COG3620	sequence-specific DNA binding
EXW26_RS05185	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW26_RS05190	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW26_RS05195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW26_RS05200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW26_RS05205	COG1695	Transcriptional regulator
EXW26_RS05225	COG1595	DNA-templated transcription, initiation
EXW26_RS05240	COG3973	AAA domain
EXW26_RS05245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_RS05270	COG0537	adenosine 5'-monophosphoramidase activity
EXW26_RS05275	COG1131	(ABC) transporter
EXW26_RS05280	COG4473	ABC transporter
EXW26_RS05290	COG0247	lactate metabolic process
EXW26_RS05295	COG1139	Iron-sulfur cluster binding protein
EXW26_RS05300	COG1556	Lactate utilization protein
EXW26_RS05320	COG3402	PFAM membrane-flanked domain
EXW26_RS05325	COG3428	Bacterial PH domain
EXW26_RS05365	COG3402	PFAM membrane-flanked domain
EXW26_RS05370	COG3428	Bacterial PH domain
EXW26_RS05375	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_RS05380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS05385	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW26_RS05390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW26_RS05395	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW26_RS05415	COG1309	transcriptional regulator
EXW26_RS05420	COG1511	domain protein
EXW26_RS05455	COG1609	Transcriptional regulator
EXW26_RS05465	COG1234	tRNA 3'-trailer cleavage
EXW26_RS05470	COG0095	Lipoate-protein ligase
EXW26_RS05480	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS05495	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW26_RS05505	COG4208	sulfate ABC transporter
EXW26_RS05520	COG1408	metallophosphoesterase
EXW26_RS05525	COG1078	dGTPase activity
EXW26_RS05540	COG1595	DNA-templated transcription, initiation
EXW26_RS05545	COG2207	Transcriptional regulator
EXW26_RS05545	COG3708	Transcriptional regulator
EXW26_RS05550	COG2205	protein histidine kinase activity
EXW26_RS05555	COG0745	RESPONSE REGULATOR receiver
EXW26_RS05575	COG0501	Belongs to the peptidase M48B family
EXW26_RS05580	COG0840	transmembrane signaling receptor activity
EXW26_RS05585	COG0697	spore germination
EXW26_RS05590	COG3693	PFAM glycoside hydrolase, family 10
EXW26_RS05595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW26_RS05600	COG2224	Isocitrate lyase
EXW26_RS05610	COG1278	Cold shock
EXW26_RS05625	COG4903	ComK protein
EXW26_RS05630	COG0398	Pfam SNARE associated Golgi protein
EXW26_RS05640	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW26_RS05645	COG1074	ATP-dependent DNA helicase activity
EXW26_RS05695	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW26_RS05720	COG0367	asparagine synthase
EXW26_RS05735	COG0753	catalase activity
EXW26_RS05740	COG0004	ammonium transporteR
EXW26_RS05750	COG1666	GTP binding
EXW26_RS05755	COG2996	Protein conserved in bacteria
EXW26_RS05770	COG1329	Transcriptional regulator
EXW26_RS05800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_RS05810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS05825	COG0561	phosphatase activity
EXW26_RS05845	COG2267	carboxylic ester hydrolase activity
EXW26_RS05860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS05865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW26_RS05870	COG5504	Zn-dependent protease
EXW26_RS05880	COG0180	Tryptophanyl-tRNA synthetase
EXW26_RS05890	COG4166	transmembrane transport
EXW26_RS05895	COG0601	transmembrane transport
EXW26_RS05900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW26_RS05905	COG0444	Belongs to the ABC transporter superfamily
EXW26_RS05910	COG4608	Belongs to the ABC transporter superfamily
EXW26_RS05915	COG0534	Mate efflux family protein
EXW26_RS05920	COG4166	transmembrane transport
EXW26_RS05935	COG0861	Integral membrane protein TerC family
EXW26_RS05940	COG4862	establishment of competence for transformation
EXW26_RS05945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_RS05955	COG1164	Oligoendopeptidase f
EXW26_RS05965	COG2346	COG2346, Truncated hemoglobins
EXW26_RS05970	COG4116	CYTH
EXW26_RS05980	COG2357	RelA SpoT domain protein
EXW26_RS05990	COG0564	pseudouridine synthase activity
EXW26_RS06000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW26_RS06005	COG0772	Belongs to the SEDS family
EXW26_RS06010	COG1216	Glycosyl transferase, family 2
EXW26_RS06030	COG0457	Tetratricopeptide repeat
EXW26_RS06030	COG0463	Glycosyl transferase, family 2
EXW26_RS06050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW26_RS06065	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW26_RS06110	COG2153	protein acetylation
EXW26_RS06115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW26_RS06120	COG2382	esterase
EXW26_RS06145	COG5492	domain, Protein
EXW26_RS06150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_RS06160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW26_RS06160	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW26_RS06165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW26_RS06170	COG0134	indole-3-glycerol-phosphate synthase activity
EXW26_RS06175	COG0135	phosphoribosylanthranilate isomerase activity
EXW26_RS06180	COG0133	tryptophan synthase activity
EXW26_RS06185	COG0159	tryptophan synthase activity
EXW26_RS06195	COG1620	l-lactate permease
EXW26_RS06200	COG5634	Uncharacterized conserved protein (DUF2278)
EXW26_RS06250	COG2226	methyltransferase
EXW26_RS06270	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_RS06275	COG0567	Dehydrogenase, E1 component
EXW26_RS06280	COG1476	TRANSCRIPTIONal
EXW26_RS06305	COG4152	abc transporter atp-binding protein
EXW26_RS06310	COG1668	transmembrane transport
EXW26_RS06360	COG0582	viral genome integration into host DNA
EXW26_RS06400	COG1686	Belongs to the peptidase S11 family
EXW26_RS06405	COG0681	Belongs to the peptidase S26 family
EXW26_RS06440	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS06450	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW26_RS06455	COG1177	transmembrane transport
EXW26_RS06460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW26_RS06470	COG2409	Drug exporters of the RND superfamily
EXW26_RS06480	COG0564	pseudouridine synthase activity
EXW26_RS06490	COG2340	Cysteine-rich secretory protein family
EXW26_RS06495	COG0247	lactate metabolic process
EXW26_RS06500	COG0277	FAD linked oxidase domain protein
EXW26_RS06505	COG3835	regulator
EXW26_RS06515	COG0745	RESPONSE REGULATOR receiver
EXW26_RS06520	COG5002	protein histidine kinase activity
EXW26_RS06525	COG2186	Transcriptional regulator
EXW26_RS06530	COG0247	lactate metabolic process
EXW26_RS06535	COG1139	Iron-sulfur cluster binding protein
EXW26_RS06540	COG1556	Lactate utilization protein
EXW26_RS06545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW26_RS06555	COG2116	formate transmembrane transporter activity
EXW26_RS06560	COG0861	Integral membrane protein TerC family
EXW26_RS06565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_RS06575	COG2030	dehydratase
EXW26_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS06600	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW26_RS06610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_RS06625	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW26_RS06630	COG3842	ATPase activity
EXW26_RS06645	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW26_RS06655	COG1349	DNA-binding transcription factor activity
EXW26_RS06665	COG0235	Class ii aldolase
EXW26_RS06675	COG2861	carbohydrate metabolic process
EXW26_RS06685	COG3852	Histidine kinase
EXW26_RS06690	COG1846	Transcriptional regulator
EXW26_RS06700	COG2318	DinB family
EXW26_RS06705	COG5002	protein histidine kinase activity
EXW26_RS06710	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW26_RS06715	COG0720	synthase
EXW26_RS06725	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW26_RS06730	COG4873	Protein conserved in bacteria
EXW26_RS06745	COG0456	acetyltransferase
EXW26_RS06760	COG1780	Probably involved in ribonucleotide reductase function
EXW26_RS06775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW26_RS06780	COG0531	amino acid
EXW26_RS06785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW26_RS06800	COG2204	response regulator
EXW26_RS06805	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS06815	COG1725	Transcriptional regulator
EXW26_RS06820	COG1131	(ABC) transporter
EXW26_RS06830	COG1131	(ABC) transporter
EXW26_RS06835	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_RS06840	COG1266	CAAX protease self-immunity
EXW26_RS06850	COG1522	sequence-specific DNA binding
EXW26_RS06860	COG1335	isochorismatase
EXW26_RS06870	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_RS06875	COG2070	2-Nitropropane dioxygenase
EXW26_RS06880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW26_RS06885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_RS06890	COG1696	Membrane protein involved in D-alanine export
EXW26_RS06895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_RS06915	COG0716	FMN binding
EXW26_RS06950	COG0534	Mate efflux family protein
EXW26_RS06975	COG1846	Transcriptional regulator
EXW26_RS06985	COG1301	dicarboxylic acid transport
EXW26_RS06990	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW26_RS07000	COG3874	Sporulation protein YtfJ
EXW26_RS07020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_RS07025	COG0028	Belongs to the TPP enzyme family
EXW26_RS07030	COG0440	acetolactate synthase activity
EXW26_RS07040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW26_RS07050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW26_RS07060	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW26_RS07065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW26_RS07075	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW26_RS07080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW26_RS07085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW26_RS07090	COG0107	imidazoleglycerol-phosphate synthase activity
EXW26_RS07100	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW26_RS07105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW26_RS07120	COG1183	phosphatidylcholine synthase activity
EXW26_RS07125	COG1368	sulfuric ester hydrolase activity
EXW26_RS07135	COG0019	diaminopimelate decarboxylase activity
EXW26_RS07145	COG0175	sulfate reduction
EXW26_RS07150	COG2046	Belongs to the sulfate adenylyltransferase family
EXW26_RS07155	COG0529	Catalyzes the synthesis of activated sulfate
EXW26_RS07160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW26_RS07180	COG1648	precorrin-2 dehydrogenase activity
EXW26_RS07185	COG0733	neurotransmitter:sodium symporter activity
EXW26_RS07210	COG1757	Na H antiporter
EXW26_RS07230	COG4758	membrane
EXW26_RS07235	COG4585	Histidine kinase
EXW26_RS07240	COG2197	response regulator
EXW26_RS07250	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS07260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW26_RS07300	COG0730	response to heat
EXW26_RS07305	COG0306	phosphate transporter
EXW26_RS07310	COG1392	Phosphate transport regulator
EXW26_RS07315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS07330	COG3852	Histidine kinase
EXW26_RS07335	COG1801	Protein of unknown function DUF72
EXW26_RS07345	COG0582	viral genome integration into host DNA
EXW26_RS07350	COG5002	protein histidine kinase activity
EXW26_RS07365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW26_RS07365	COG0392	lysyltransferase activity
EXW26_RS07380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_RS07385	COG1686	Belongs to the peptidase S11 family
EXW26_RS07390	COG2715	membrane protein required for spore maturation
EXW26_RS07395	COG0700	Nucleoside recognition
EXW26_RS07400	COG1187	pseudouridine synthase activity
EXW26_RS07410	COG1333	cytochrome c biogenesis protein
EXW26_RS07415	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW26_RS07420	COG0745	RESPONSE REGULATOR receiver
EXW26_RS07425	COG5002	protein histidine kinase activity
EXW26_RS07430	COG2096	Adenosyltransferase
EXW26_RS07435	COG4942	peptidase
EXW26_RS07445	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW26_RS07450	COG1141	Ferredoxin
EXW26_RS07455	COG4955	Helix-turn-helix domain
EXW26_RS07460	COG0514	ATP-dependent DNA helicase (RecQ)
EXW26_RS07465	COG1266	CAAX protease self-immunity
EXW26_RS07475	COG1408	metallophosphoesterase
EXW26_RS07490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW26_RS07510	COG0492	ferredoxin-NADP+ reductase activity
EXW26_RS07515	COG0252	asparaginase activity
EXW26_RS07525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW26_RS07535	COG1304	FMN binding
EXW26_RS07565	COG1160	GTP binding
EXW26_RS07570	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW26_RS07590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_RS07600	COG0302	gtp cyclohydrolase
EXW26_RS07605	COG0142	geranyltranstransferase activity
EXW26_RS07610	COG2226	methyltransferase
EXW26_RS07615	COG0142	geranyltranstransferase activity
EXW26_RS07630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW26_RS07640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW26_RS07645	COG0457	Tetratricopeptide repeat
EXW26_RS07650	COG5582	Belongs to the UPF0302 family
EXW26_RS07665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW26_RS07680	COG4347	Protein of unknown function (DUF1405)
EXW26_RS07695	COG2738	Putative neutral zinc metallopeptidase
EXW26_RS07705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS07710	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW26_RS07715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW26_RS07720	COG1803	Methylglyoxal synthase
EXW26_RS07725	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_RS07730	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS07735	COG0617	tRNA 3'-terminal CCA addition
EXW26_RS07745	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW26_RS07750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW26_RS07760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW26_RS07760	COG1199	ATP-dependent helicase activity
EXW26_RS07780	COG3935	DnaD domain protein
EXW26_RS07785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW26_RS07795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS07795	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_RS07800	COG3331	DNA recombination
EXW26_RS07835	COG4474	Belongs to the UPF0398 family
EXW26_RS07840	COG3599	regulation of cell shape
EXW26_RS07850	COG0116	Belongs to the methyltransferase superfamily
EXW26_RS07855	COG4974	Belongs to the 'phage' integrase family
EXW26_RS07945	COG1199	ATP-dependent helicase activity
EXW26_RS07950	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW26_RS07960	COG0024	Methionine aminopeptidase
EXW26_RS07970	COG2233	PERMEase
EXW26_RS07975	COG2311	Membrane
EXW26_RS07985	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_RS07995	COG0456	acetyltransferase
EXW26_RS08045	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_RS08060	COG0454	-acetyltransferase
EXW26_RS08080	COG0328	RNA-DNA hybrid ribonuclease activity
EXW26_RS08115	COG3403	YqcI/YcgG family
EXW26_RS08120	COG1280	lysine exporter protein (LysE YggA)
EXW26_RS08135	COG3162	membrane
EXW26_RS08140	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW26_RS08145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_RS08155	COG0475	glutathione-regulated potassium exporter activity
EXW26_RS08160	COG0789	Transcriptional regulator
EXW26_RS08160	COG4978	Transcriptional regulator
EXW26_RS08165	COG0534	Mate efflux family protein
EXW26_RS08170	COG2323	membrane
EXW26_RS08175	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW26_RS08200	COG2814	Major facilitator Superfamily
EXW26_RS08220	COG1923	regulation of RNA biosynthetic process
EXW26_RS08230	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW26_RS08235	COG1360	Flagellar Motor Protein
EXW26_RS08240	COG2201	protein-glutamate methylesterase activity
EXW26_RS08245	COG0643	Histidine kinase
EXW26_RS08245	COG2198	Histidine kinase
EXW26_RS08250	COG1776	CheC inhibitor of MCP methylation
EXW26_RS08250	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_RS08265	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW26_RS08285	COG1256	bacterial-type flagellum assembly
EXW26_RS08290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_RS08310	COG1815	bacterial-type flagellum-dependent cell motility
EXW26_RS08315	COG1558	bacterial-type flagellum-dependent cell motility
EXW26_RS08325	COG1766	The M ring may be actively involved in energy transduction
EXW26_RS08330	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_RS08340	COG1157	protein secretion by the type III secretion system
EXW26_RS08360	COG1749	Flagellar hook protein flgE
EXW26_RS08375	COG0835	chemotaxis
EXW26_RS08375	COG0784	Response regulator, receiver
EXW26_RS08395	COG0861	Integral membrane protein TerC family
EXW26_RS08405	COG3383	formate dehydrogenase (NAD+) activity
EXW26_RS08410	COG2427	Protein of unknown function (DUF1641)
EXW26_RS08415	COG5609	conserved protein (DUF2294)
EXW26_RS08420	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW26_RS08430	COG2116	formate transmembrane transporter activity
EXW26_RS08435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_RS08440	COG0303	'Molybdopterin
EXW26_RS08445	COG0314	molybdopterin synthase activity
EXW26_RS08450	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW26_RS08460	COG0489	protein tyrosine kinase activity
EXW26_RS08465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_RS08470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_RS08475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_RS08480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW26_RS08485	COG0741	lytic transglycosylase activity
EXW26_RS08495	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_RS08500	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW26_RS08500	COG1776	CheC inhibitor of MCP methylation
EXW26_RS08510	COG1338	Plays a role in the flagellum-specific transport system
EXW26_RS08515	COG1987	bacterial-type flagellum assembly
EXW26_RS08525	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW26_RS08530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW26_RS08535	COG1419	protein localization to endoplasmic reticulum
EXW26_RS08540	COG4786	Flagellar basal body rod
EXW26_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_RS08585	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_RS08600	COG2814	Major facilitator Superfamily
EXW26_RS08610	COG0583	DNA-binding transcription factor activity
EXW26_RS08615	COG3842	ATPase activity
EXW26_RS08665	COG0406	alpha-ribazole phosphatase activity
EXW26_RS08695	COG0367	asparagine synthase
EXW26_RS08725	COG1802	Transcriptional regulator
EXW26_RS08730	COG0697	spore germination
EXW26_RS08735	COG1216	Glycosyl transferase, family 2
EXW26_RS08735	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS08740	COG1757	Na H antiporter
EXW26_RS08765	COG0534	Mate efflux family protein
EXW26_RS08770	COG3340	Belongs to the peptidase S51 family
EXW26_RS08790	COG0785	Cytochrome C biogenesis protein
EXW26_RS08795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS08810	COG3048	D-serine ammonia-lyase activity
EXW26_RS08815	COG2733	membrane
EXW26_RS08840	COG2197	response regulator
EXW26_RS08850	COG1131	(ABC) transporter
EXW26_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_RS08875	COG0528	UMP kinase activity
EXW26_RS08885	COG1027	Aspartate ammonia-lyase
EXW26_RS08890	COG0281	malic enzyme
EXW26_RS08895	COG4191	Histidine kinase
EXW26_RS08900	COG0784	Response regulator, receiver
EXW26_RS08905	COG1846	Transcriptional regulator
EXW26_RS08915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_RS08925	COG2502	aspartate--ammonia ligase
EXW26_RS08930	COG3620	sequence-specific DNA binding
EXW26_RS08990	COG1695	Transcriptional regulator
EXW26_RS09005	COG0477	Major facilitator Superfamily
EXW26_RS09015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS09025	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW26_RS09030	COG2223	nitrite transmembrane transporter activity
EXW26_RS09035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_RS09050	COG2244	polysaccharide biosynthetic process
EXW26_RS09055	COG0733	neurotransmitter:sodium symporter activity
EXW26_RS09065	COG5566	PFAM Mor transcription activator
EXW26_RS09070	COG2323	membrane
EXW26_RS09090	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_RS09095	COG2132	Multicopper oxidase
EXW26_RS09105	COG5002	protein histidine kinase activity
EXW26_RS09110	COG0745	RESPONSE REGULATOR receiver
EXW26_RS09120	COG0129	dihydroxy-acid dehydratase activity
EXW26_RS09125	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW26_RS09150	COG2814	Major facilitator Superfamily
EXW26_RS09155	COG3384	dioxygenase
EXW26_RS09190	COG1073	alpha beta
EXW26_RS09195	COG4166	transmembrane transport
EXW26_RS09200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS09205	COG0745	RESPONSE REGULATOR receiver
EXW26_RS09220	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW26_RS09225	COG1054	Belongs to the UPF0176 family
EXW26_RS09235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW26_RS09240	COG0531	amino acid
EXW26_RS09275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW26_RS09290	COG4257	antibiotic catabolic process
EXW26_RS09295	COG2390	Transcriptional regulator
EXW26_RS09305	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW26_RS09310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS09315	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW26_RS09330	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW26_RS09345	COG0583	DNA-binding transcription factor activity
EXW26_RS09360	COG0006	proline dipeptidase activity
EXW26_RS09365	COG2132	Multicopper oxidase
EXW26_RS09375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW26_RS09395	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS09405	COG1276	copper resistance
EXW26_RS09405	COG2372	response to copper ion
EXW26_RS09410	COG4549	nuclear export factor GLE1
EXW26_RS09420	COG0697	spore germination
EXW26_RS09425	COG0583	DNA-binding transcription factor activity
EXW26_RS09430	COG1959	2 iron, 2 sulfur cluster binding
EXW26_RS09435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW26_RS09440	COG0778	Nitroreductase
EXW26_RS09450	COG0628	permease
EXW26_RS09465	COG1231	oxidoreductase activity
EXW26_RS09470	COG0523	cobalamin synthesis protein
EXW26_RS09480	COG0411	ABC transporter
EXW26_RS09500	COG0583	DNA-binding transcription factor activity
EXW26_RS09510	COG1942	4-Oxalocrotonate Tautomerase
EXW26_RS09525	COG0346	lactoylglutathione lyase activity
EXW26_RS09535	COG1271	oxidase subunit
EXW26_RS09540	COG1294	oxidase, subunit
EXW26_RS09545	COG4988	ABC transporter
EXW26_RS09550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW26_RS09575	COG1686	Belongs to the peptidase S11 family
EXW26_RS09590	COG0791	NLP P60 protein
EXW26_RS09590	COG1388	LysM domain
EXW26_RS09600	COG1132	(ABC) transporter
EXW26_RS09605	COG0745	RESPONSE REGULATOR receiver
EXW26_RS09610	COG5002	protein histidine kinase activity
EXW26_RS09615	COG0300	oxidoreductase activity
EXW26_RS09620	COG4122	O-methyltransferase activity
EXW26_RS09640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW26_RS09650	COG0460	homoserine dehydrogenase
EXW26_RS09660	COG0083	homoserine kinase activity
EXW26_RS09675	COG1316	TRANSCRIPTIONal
EXW26_RS09690	COG1285	pathogenesis
EXW26_RS09695	COG1247	-acetyltransferase
EXW26_RS09715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_RS09725	COG1082	Xylose isomerase domain protein TIM barrel
EXW26_RS09735	COG2814	Major facilitator Superfamily
EXW26_RS09740	COG1279	arginine transmembrane transporter activity
EXW26_RS09745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS09755	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW26_RS09785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW26_RS09790	COG0577	efflux transmembrane transporter activity
EXW26_RS09795	COG2002	toxin-antitoxin pair type II binding
EXW26_RS09800	COG1404	Belongs to the peptidase S8 family
EXW26_RS09805	COG0640	Transcriptional regulator
EXW26_RS09810	COG0667	Aldo Keto reductase
EXW26_RS09850	COG3949	Membrane
EXW26_RS09855	COG0783	Belongs to the Dps family
EXW26_RS09870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW26_RS09880	COG1231	oxidoreductase activity
EXW26_RS09885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS09890	COG4989	oxidoreductase activity
EXW26_RS09895	COG0523	cobalamin synthesis protein
EXW26_RS09900	COG0456	acetyltransferase
EXW26_RS09905	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW26_RS09930	COG1136	(ABC) transporter
EXW26_RS09935	COG0577	efflux transmembrane transporter activity
EXW26_RS09940	COG0745	RESPONSE REGULATOR receiver
EXW26_RS09945	COG2205	protein histidine kinase activity
EXW26_RS09950	COG1902	pentaerythritol trinitrate reductase activity
EXW26_RS09955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW26_RS09965	COG4166	transmembrane transport
EXW26_RS09970	COG0346	lactoylglutathione lyase activity
EXW26_RS09980	COG0406	alpha-ribazole phosphatase activity
EXW26_RS09990	COG5337	Spore coat protein CotH
EXW26_RS09995	COG1051	belongs to the nudix hydrolase family
EXW26_RS10000	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS10005	COG2244	polysaccharide biosynthetic process
EXW26_RS10015	COG0701	Predicted permease
EXW26_RS10020	COG3689	TIGRFAM TIGR03943 family protein
EXW26_RS10025	COG1607	acyl-coa hydrolase
EXW26_RS10035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_RS10050	COG0702	epimerase
EXW26_RS10055	COG2839	Protein conserved in bacteria
EXW26_RS10060	COG1253	flavin adenine dinucleotide binding
EXW26_RS10085	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS10090	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_RS10105	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS10115	COG1876	peptidase activity
EXW26_RS10120	COG0494	nUDIX hydrolase
EXW26_RS10130	COG2211	Major facilitator Superfamily
EXW26_RS10145	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS10155	COG0561	phosphatase activity
EXW26_RS10160	COG1846	Transcriptional regulator
EXW26_RS10165	COG2814	Major facilitator Superfamily
EXW26_RS10175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_RS10180	COG4106	trans-aconitate 2-methyltransferase activity
EXW26_RS10195	COG1819	glycosyl
EXW26_RS10200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS10205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS10230	COG0456	acetyltransferase
EXW26_RS10250	COG3874	Sporulation protein YtfJ
EXW26_RS10275	COG2226	methyltransferase
EXW26_RS10305	COG0604	alcohol dehydrogenase
EXW26_RS10310	COG1595	DNA-templated transcription, initiation
EXW26_RS10330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW26_RS10330	COG0426	domain, Protein
EXW26_RS10340	COG0386	Belongs to the glutathione peroxidase family
EXW26_RS10345	COG1305	Transglutaminase-like
EXW26_RS10350	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW26_RS10355	COG0714	Associated with various cellular activities
EXW26_RS10360	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW26_RS10365	COG1140	nitrate reductase beta subunit
EXW26_RS10370	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW26_RS10375	COG2181	nitrate reductase activity
EXW26_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW26_RS10385	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW26_RS10390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_RS10395	COG0303	'Molybdopterin
EXW26_RS10400	COG0314	molybdopterin synthase activity
EXW26_RS10410	COG2223	nitrite transmembrane transporter activity
EXW26_RS10430	COG1648	precorrin-2 dehydrogenase activity
EXW26_RS10440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW26_RS10440	COG1587	Uroporphyrinogen-III synthase
EXW26_RS10445	COG2146	nitrite reductase [NAD(P)H] activity
EXW26_RS10450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW26_RS10455	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW26_RS10485	COG2359	stage V sporulation protein S
EXW26_RS10495	COG2856	Zn peptidase
EXW26_RS10515	COG1396	sequence-specific DNA binding
EXW26_RS10600	COG0582	viral genome integration into host DNA
EXW26_RS10605	COG1476	TRANSCRIPTIONal
EXW26_RS10635	COG0582	viral genome integration into host DNA
EXW26_RS10645	COG5484	DNA packaging
EXW26_RS10650	COG1783	phage Terminase large subunit
EXW26_RS10665	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EXW26_RS10670	COG4653	Phage capsid family
EXW26_RS10795	COG1418	mRNA catabolic process
EXW26_RS10800	COG0488	(ABC) transporter
EXW26_RS10820	COG1413	lyase activity
EXW26_RS10835	COG2136	Putative SAM-dependent methyltransferase
EXW26_RS10835	COG2521	methyltransferase
EXW26_RS10840	COG0018	arginyl-trna synthetase
EXW26_RS10890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW26_RS10895	COG0017	Asparaginyl-tRNA synthetase
EXW26_RS10900	COG0733	neurotransmitter:sodium symporter activity
EXW26_RS10925	COG2610	gluconate transmembrane transporter activity
EXW26_RS10935	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_RS10945	COG0456	acetyltransferase
EXW26_RS10950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW26_RS10955	COG1131	(ABC) transporter
EXW26_RS10960	COG4473	ABC transporter
EXW26_RS10970	COG0546	phosphoglycolate phosphatase activity
EXW26_RS11015	COG0768	penicillin binding
EXW26_RS11025	COG0204	Acyl-transferase
EXW26_RS11030	COG1272	protein, Hemolysin III
EXW26_RS11035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW26_RS11040	COG0805	protein transport
EXW26_RS11055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW26_RS11060	COG1999	signal sequence binding
EXW26_RS11065	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW26_RS11070	COG0367	asparagine synthase
EXW26_RS11085	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS11090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS11095	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW26_RS11115	COG1335	isochorismatase
EXW26_RS11125	COG0668	transmembrane transport
EXW26_RS11130	COG2203	Gaf domain
EXW26_RS11130	COG4585	Histidine kinase
EXW26_RS11135	COG2197	response regulator
EXW26_RS11140	COG1737	Transcriptional regulator
EXW26_RS11145	COG1064	alcohol dehydrogenase
EXW26_RS11160	COG1070	Carbohydrate kinase
EXW26_RS11170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW26_RS11190	COG1125	glycine betaine transport
EXW26_RS11190	COG0517	IMP dehydrogenase activity
EXW26_RS11195	COG1174	glycine betaine transport
EXW26_RS11230	COG1253	flavin adenine dinucleotide binding
EXW26_RS11235	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS11240	COG5506	Protein of unknown function (DUF1694)
EXW26_RS11255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_RS11260	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW26_RS11265	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW26_RS11270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_RS11275	COG0456	acetyltransferase
EXW26_RS11280	COG3829	transcription factor binding
EXW26_RS11285	COG1509	lysine 2,3-aminomutase activity
EXW26_RS11295	COG4479	Belongs to the UPF0346 family
EXW26_RS11305	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW26_RS11360	COG5293	efflux transmembrane transporter activity
EXW26_RS11400	COG4991	sh3 domain protein
EXW26_RS11400	COG3064	Membrane
EXW26_RS11400	COG0515	serine threonine protein kinase
EXW26_RS11410	COG0671	phosphoesterase, PA-phosphatase related
EXW26_RS11415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW26_RS11420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS11475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW26_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS11520	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_RS11520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS11530	COG2814	Major facilitator Superfamily
EXW26_RS11540	COG0372	Belongs to the citrate synthase family
EXW26_RS11545	COG2079	MmgE PrpD family protein
EXW26_RS11550	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW26_RS11555	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS11560	COG2084	Dehydrogenase
EXW26_RS11565	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS11570	COG1280	lysine exporter protein (LysE YggA)
EXW26_RS11575	COG1024	Enoyl-CoA hydratase
EXW26_RS11590	COG0420	3'-5' exonuclease activity
EXW26_RS11615	COG2223	nitrite transmembrane transporter activity
EXW26_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS11625	COG1169	isochorismate synthase
EXW26_RS11630	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW26_RS11635	COG1535	isochorismatase
EXW26_RS11635	COG3433	isochorismatase activity
EXW26_RS11640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_RS11645	COG3251	PFAM MbtH domain protein
EXW26_RS11650	COG2814	Major facilitator Superfamily
EXW26_RS11665	COG0776	regulation of translation
EXW26_RS11675	COG2318	DinB family
EXW26_RS11680	COG1115	amino acid carrier protein
EXW26_RS11695	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_RS11705	COG1187	pseudouridine synthase activity
EXW26_RS11710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW26_RS11715	COG3655	Transcriptional regulator
EXW26_RS11725	COG1136	(ABC) transporter
EXW26_RS11735	COG0596	Alpha beta hydrolase
EXW26_RS11750	COG0028	Belongs to the TPP enzyme family
EXW26_RS11770	COG1253	flavin adenine dinucleotide binding
EXW26_RS11815	COG1846	Transcriptional regulator
EXW26_RS11825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS11830	COG1309	transcriptional regulator
EXW26_RS11840	COG0697	spore germination
EXW26_RS11845	COG0531	amino acid
EXW26_RS11860	COG1247	-acetyltransferase
EXW26_RS11895	COG0596	Alpha beta hydrolase
EXW26_RS11900	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW26_RS11910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS11940	COG0583	DNA-binding transcription factor activity
EXW26_RS11945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW26_RS11960	COG0583	DNA-binding transcription factor activity
EXW26_RS11965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW26_RS11970	COG2258	MOSC domain
EXW26_RS11980	COG1132	(ABC) transporter
EXW26_RS11985	COG1132	(ABC) transporter
EXW26_RS12005	COG1396	sequence-specific DNA binding
EXW26_RS12040	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW26_RS12045	COG1595	DNA-templated transcription, initiation
EXW26_RS12070	COG1649	PFAM Uncharacterised BCR, COG1649
EXW26_RS12090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW26_RS12095	COG2971	BadF BadG BcrA BcrD
EXW26_RS12155	COG0500	methyltransferase
EXW26_RS12155	COG3615	Tellurite resistance protein tehB
EXW26_RS12165	COG0693	protein deglycase activity
EXW26_RS12175	COG0588	phosphoglycerate mutase activity
EXW26_RS12200	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_RS12210	COG0110	maltose O-acetyltransferase activity
EXW26_RS12215	COG1136	(ABC) transporter
EXW26_RS12240	COG1686	Belongs to the peptidase S11 family
EXW26_RS12265	COG0768	penicillin binding
EXW26_RS12270	COG0745	RESPONSE REGULATOR receiver
EXW26_RS12275	COG2205	protein histidine kinase activity
EXW26_RS12280	COG1136	(ABC) transporter
EXW26_RS12285	COG0577	efflux transmembrane transporter activity
EXW26_RS12295	COG1595	DNA-templated transcription, initiation
EXW26_RS12305	COG0768	penicillin binding
EXW26_RS12310	COG0768	penicillin binding
EXW26_RS12345	COG1252	NADH dehydrogenase
EXW26_RS12350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS12350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS12365	COG0697	spore germination
EXW26_RS12395	COG3397	chitin binding
EXW26_RS12400	COG0823	Involved in the tonB-independent uptake of proteins
EXW26_RS12410	COG1408	metallophosphoesterase
EXW26_RS12420	COG1131	(ABC) transporter
EXW26_RS12430	COG1309	transcriptional regulator
EXW26_RS12440	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS12445	COG0439	Biotin carboxylase
EXW26_RS12450	COG0511	ligase activity, forming carbon-carbon bonds
EXW26_RS12455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW26_RS12460	COG1024	Enoyl-CoA hydratase
EXW26_RS12465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW26_RS12470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_RS12515	COG0572	uridine kinase
EXW26_RS12550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_RS12580	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW26_RS12605	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS12610	COG1733	regulation of RNA biosynthetic process
EXW26_RS12635	COG1309	transcriptional regulator
EXW26_RS12665	COG0697	spore germination
EXW26_RS12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS12700	COG2323	membrane
EXW26_RS12715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS12720	COG0697	spore germination
EXW26_RS12740	COG0201	protein transport
EXW26_RS12750	COG0737	Belongs to the 5'-nucleotidase family
EXW26_RS12755	COG3227	Zinc metalloprotease (Elastase)
EXW26_RS12760	COG1523	belongs to the glycosyl hydrolase 13 family
EXW26_RS12785	COG1073	alpha beta
EXW26_RS12795	COG0577	efflux transmembrane transporter activity
EXW26_RS12800	COG1136	(ABC) transporter
EXW26_RS12830	COG5002	protein histidine kinase activity
EXW26_RS12835	COG0745	RESPONSE REGULATOR receiver
EXW26_RS12840	COG1011	Hydrolase
EXW26_RS12865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_RS12870	COG1183	phosphatidylcholine synthase activity
EXW26_RS12885	COG1132	(ABC) transporter
EXW26_RS12890	COG3961	Belongs to the TPP enzyme family
EXW26_RS12910	COG0322	excinuclease ABC activity
EXW26_RS12935	COG2318	DinB family
EXW26_RS12950	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW26_RS12975	COG3878	Protein conserved in bacteria
EXW26_RS12995	COG1051	belongs to the nudix hydrolase family
EXW26_RS13000	COG0592	DNA-directed DNA polymerase activity
EXW26_RS13005	COG2816	NAD+ diphosphatase activity
EXW26_RS13015	COG2223	nitrite transmembrane transporter activity
EXW26_RS13025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_RS13035	COG0494	nUDIX hydrolase
EXW26_RS13055	COG0697	spore germination
EXW26_RS13060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS13075	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_RS13090	COG1733	regulation of RNA biosynthetic process
EXW26_RS13100	COG2814	Major facilitator Superfamily
EXW26_RS13110	COG2375	cellular response to nickel ion
EXW26_RS13110	COG1132	(ABC) transporter
EXW26_RS13115	COG1132	(ABC) transporter
EXW26_RS13150	COG0768	penicillin binding
EXW26_RS13155	COG0671	phosphoesterase, PA-phosphatase related
EXW26_RS13160	COG0604	alcohol dehydrogenase
EXW26_RS13165	COG5002	protein histidine kinase activity
EXW26_RS13170	COG0745	RESPONSE REGULATOR receiver
EXW26_RS13180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_RS13190	COG2205	protein histidine kinase activity
EXW26_RS13205	COG1122	ATPase activity
EXW26_RS13210	COG4720	Psort location CytoplasmicMembrane, score
EXW26_RS13215	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_RS13220	COG1819	glycosyl
EXW26_RS13230	COG0768	penicillin binding
EXW26_RS13235	COG5002	protein histidine kinase activity
EXW26_RS13240	COG0561	phosphatase activity
EXW26_RS13285	COG2124	cytochrome p450
EXW26_RS13335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW26_RS13345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS13350	COG0460	homoserine dehydrogenase
EXW26_RS13370	COG0577	efflux transmembrane transporter activity
EXW26_RS13375	COG1136	(ABC) transporter
EXW26_RS13385	COG0488	(ABC) transporter
EXW26_RS13390	COG0667	Aldo Keto reductase
EXW26_RS13395	COG0583	DNA-binding transcription factor activity
EXW26_RS13400	COG2205	protein histidine kinase activity
EXW26_RS13405	COG0745	RESPONSE REGULATOR receiver
EXW26_RS13415	COG3773	Cell wall hydrolase
EXW26_RS13420	COG0604	alcohol dehydrogenase
EXW26_RS13450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS13465	COG2959	enzyme of heme biosynthesis
EXW26_RS13490	COG3483	tryptophan 2,3-dioxygenase activity
EXW26_RS13495	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW26_RS13500	COG3844	kynureninase activity
EXW26_RS13505	COG1309	transcriptional regulator
EXW26_RS13540	COG1349	DNA-binding transcription factor activity
EXW26_RS13565	COG2223	nitrite transmembrane transporter activity
EXW26_RS13575	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS13580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_RS13580	COG0456	acetyltransferase
EXW26_RS13615	COG4176	ABC-type proline glycine betaine transport system permease component
EXW26_RS13620	COG0517	IMP dehydrogenase activity
EXW26_RS13620	COG4175	Glycine betaine
EXW26_RS13645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW26_RS13650	COG2153	protein acetylation
EXW26_RS13655	COG3397	chitin binding
EXW26_RS13665	COG1819	glycosyl
EXW26_RS13680	COG2205	protein histidine kinase activity
EXW26_RS13685	COG2315	Protein conserved in bacteria
EXW26_RS13725	COG3973	AAA domain
EXW26_RS13740	COG2105	PFAM AIG2 family protein
EXW26_RS13745	COG0514	ATP-dependent DNA helicase (RecQ)
EXW26_RS13770	COG4637	Psort location Cytoplasmic, score
EXW26_RS13790	COG1227	inorganic diphosphatase activity
EXW26_RS13795	COG3397	chitin binding
EXW26_RS13800	COG2318	DinB family
EXW26_RS13820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW26_RS13825	COG1115	amino acid carrier protein
EXW26_RS13830	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS13835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW26_RS13845	COG3938	Belongs to the proline racemase family
EXW26_RS13850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW26_RS13895	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS13910	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW26_RS13915	COG4166	transmembrane transport
EXW26_RS13925	COG4948	Mandelate Racemase Muconate Lactonizing
EXW26_RS13945	COG0667	Aldo Keto reductase
EXW26_RS13990	COG2936	dipeptidyl-peptidase activity
EXW26_RS13995	COG5002	protein histidine kinase activity
EXW26_RS14000	COG0745	RESPONSE REGULATOR receiver
EXW26_RS14030	COG1164	Oligoendopeptidase f
EXW26_RS14050	COG1307	EDD domain protein, DegV family
EXW26_RS14075	COG1335	isochorismatase
EXW26_RS14090	COG2814	Major facilitator Superfamily
EXW26_RS14100	COG1664	Polymer-forming cytoskeletal
EXW26_RS14105	COG0789	Transcriptional regulator
EXW26_RS14110	COG4533	DNA binding
EXW26_RS14115	COG0477	Major facilitator Superfamily
EXW26_RS14115	COG2814	Major facilitator Superfamily
EXW26_RS14130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_RS14135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW26_RS14140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_RS14145	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS14160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_RS14165	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS14170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_RS14185	COG2261	transglycosylase associated protein
EXW26_RS14200	COG2226	methyltransferase
EXW26_RS14235	COG0436	Aminotransferase
EXW26_RS14240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW26_RS14265	COG1131	(ABC) transporter
EXW26_RS14270	COG2188	Transcriptional regulator
EXW26_RS14315	COG0628	permease
EXW26_RS14345	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW26_RS14355	COG0697	spore germination
EXW26_RS14380	COG4912	Dna alkylation repair
EXW26_RS14405	COG2814	Major facilitator Superfamily
EXW26_RS14410	COG1368	sulfuric ester hydrolase activity
EXW26_RS14420	COG0488	(ABC) transporter
EXW26_RS14425	COG1033	growth of symbiont in host cell
EXW26_RS14425	COG2409	Drug exporters of the RND superfamily
EXW26_RS14430	COG1309	transcriptional regulator
EXW26_RS14445	COG0287	Prephenate dehydrogenase
EXW26_RS14460	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW26_RS14460	COG1605	Chorismate mutase
EXW26_RS14495	COG1388	LysM domain
EXW26_RS14495	COG3584	3D domain protein
EXW26_RS14505	COG0346	lactoylglutathione lyase activity
EXW26_RS14540	COG0579	oxidoreductase
EXW26_RS14550	COG2390	Transcriptional regulator
EXW26_RS14565	COG1830	Aldolase
EXW26_RS14570	COG2226	methyltransferase
EXW26_RS14585	COG0346	lactoylglutathione lyase activity
EXW26_RS14590	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_RS14610	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW26_RS14615	COG2207	Transcriptional regulator
EXW26_RS14620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS14625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW26_RS14630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW26_RS14635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_RS14640	COG3239	Fatty acid desaturase
EXW26_RS14650	COG3655	Transcriptional regulator
EXW26_RS14665	COG4377	Putative membrane peptidase family (DUF2324)
EXW26_RS14675	COG3279	Response regulator of the LytR AlgR family
EXW26_RS14690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS14695	COG0346	lactoylglutathione lyase activity
EXW26_RS14725	COG0714	Associated with various cellular activities
EXW26_RS14745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW26_RS14750	COG0753	catalase activity
EXW26_RS14760	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW26_RS14780	COG0778	Nitroreductase
EXW26_RS14785	COG1846	Transcriptional regulator
EXW26_RS14800	COG0494	nUDIX hydrolase
EXW26_RS14820	COG1725	Transcriptional regulator
EXW26_RS14850	COG2207	Transcriptional regulator
EXW26_RS14855	COG0456	acetyltransferase
EXW26_RS14870	COG0697	spore germination
EXW26_RS14875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS14880	COG1671	Belongs to the UPF0178 family
EXW26_RS14900	COG0456	acetyltransferase
EXW26_RS14900	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_RS14925	COG0730	response to heat
EXW26_RS14935	COG0833	amino acid
EXW26_RS14945	COG4335	DNA alkylation repair
EXW26_RS14975	COG0768	penicillin binding
EXW26_RS14985	COG3104	oligopeptide transport
EXW26_RS14990	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW26_RS15005	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW26_RS15010	COG1984	allophanate hydrolase subunit 2
EXW26_RS15015	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW26_RS15020	COG1414	Transcriptional regulator
EXW26_RS15040	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS15065	COG0640	Transcriptional regulator
EXW26_RS15085	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW26_RS15100	COG0574	Belongs to the PEP-utilizing enzyme family
EXW26_RS15100	COG3848	Pyruvate phosphate dikinase
EXW26_RS15125	COG1136	(ABC) transporter
EXW26_RS15155	COG1073	alpha beta
EXW26_RS15190	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW26_RS15210	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW26_RS15215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW26_RS15220	COG1121	(ABC) transporter
EXW26_RS15235	COG1999	signal sequence binding
EXW26_RS15240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW26_RS15245	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW26_RS15270	COG0798	PFAM Bile acid sodium symporter
EXW26_RS15275	COG0346	lactoylglutathione lyase activity
EXW26_RS15280	COG0640	Transcriptional regulator
EXW26_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS15335	COG1522	sequence-specific DNA binding
EXW26_RS15350	COG0346	lactoylglutathione lyase activity
EXW26_RS15370	COG2226	methyltransferase
EXW26_RS15380	COG2814	Major facilitator Superfamily
EXW26_RS15410	COG0745	RESPONSE REGULATOR receiver
EXW26_RS15415	COG3850	Histidine kinase
EXW26_RS15415	COG5002	protein histidine kinase activity
EXW26_RS15445	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW26_RS15485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_RS15495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS15515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW26_RS15535	COG1136	(ABC) transporter
EXW26_RS15540	COG0577	efflux transmembrane transporter activity
EXW26_RS15560	COG3850	Histidine kinase
EXW26_RS15560	COG5002	protein histidine kinase activity
EXW26_RS15575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS15590	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_RS15610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW26_RS15670	COG2814	Major facilitator Superfamily
EXW26_RS15685	COG1876	peptidase activity
EXW26_RS15690	COG2843	Capsule synthesis protein
EXW26_RS15705	COG0477	Major facilitator Superfamily
EXW26_RS15720	COG1846	Transcriptional regulator
EXW26_RS15725	COG2814	Major facilitator Superfamily
EXW26_RS15740	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EXW26_RS15750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS15760	COG0789	Transcriptional regulator
EXW26_RS15790	COG1476	TRANSCRIPTIONal
EXW26_RS15805	COG1288	antiporter activity
EXW26_RS15810	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW26_RS15855	COG3718	enzyme involved in inositol metabolism
EXW26_RS15860	COG0191	fructose-bisphosphate aldolase activity
EXW26_RS15885	COG0673	inositol 2-dehydrogenase activity
EXW26_RS15890	COG2814	Major facilitator Superfamily
EXW26_RS15895	COG1609	Transcriptional regulator
EXW26_RS15900	COG2003	Belongs to the UPF0758 family
EXW26_RS15960	COG0494	nUDIX hydrolase
EXW26_RS15990	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS16025	COG0739	heme binding
EXW26_RS16075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_RS16130	COG4187	Peptidase family M20/M25/M40
EXW26_RS16145	COG2031	fatty acid transporter
EXW26_RS16155	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_RS16215	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW26_RS16220	COG1288	antiporter activity
EXW26_RS16225	COG2356	endonuclease I
EXW26_RS16230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_RS16250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW26_RS16270	COG1785	Belongs to the alkaline phosphatase family
EXW26_RS16275	COG0778	Nitroreductase
EXW26_RS16280	COG1733	regulation of RNA biosynthetic process
EXW26_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS16305	COG1131	(ABC) transporter
EXW26_RS16325	COG0494	nUDIX hydrolase
EXW26_RS16340	COG1011	Hydrolase
EXW26_RS16345	COG2365	Tyrosine phosphatase family
EXW26_RS16370	COG0346	lactoylglutathione lyase activity
EXW26_RS16375	COG1940	carbohydrate kinase activity
EXW26_RS16380	COG0738	Major facilitator superfamily
EXW26_RS16385	COG0110	maltose O-acetyltransferase activity
EXW26_RS16400	COG0628	permease
EXW26_RS16405	COG2261	transglycosylase associated protein
EXW26_RS16445	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW26_RS16455	COG1253	flavin adenine dinucleotide binding
EXW26_RS16460	COG0789	Transcriptional regulator
EXW26_RS16465	COG0697	spore germination
EXW26_RS16475	COG3813	Protein conserved in bacteria
EXW26_RS16480	COG2706	6-phosphogluconolactonase activity
EXW26_RS16485	COG1070	Carbohydrate kinase
EXW26_RS16495	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW26_RS16500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW26_RS16515	COG0814	amino acid
EXW26_RS16535	COG1393	Belongs to the ArsC family
EXW26_RS16545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS16560	COG0494	nUDIX hydrolase
EXW26_RS16585	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS16595	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS16600	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_RS16605	COG1733	regulation of RNA biosynthetic process
EXW26_RS16620	COG1191	sigma factor activity
EXW26_RS16640	COG1876	peptidase activity
EXW26_RS16665	COG0741	lytic transglycosylase activity
EXW26_RS16685	COG5002	protein histidine kinase activity
EXW26_RS16690	COG0745	RESPONSE REGULATOR receiver
EXW26_RS16695	COG3344	reverse transcriptase
EXW26_RS16710	COG0657	acetylesterase activity
EXW26_RS16720	COG2814	Major facilitator Superfamily
EXW26_RS16725	COG1309	transcriptional regulator
EXW26_RS16745	COG3226	Transcriptional regulator
EXW26_RS16750	COG1280	lysine exporter protein (LysE YggA)
EXW26_RS16775	COG0814	amino acid
EXW26_RS16800	COG1151	hydroxylamine reductase activity
EXW26_RS16840	COG2072	flavoprotein involved in K transport
EXW26_RS16885	COG1695	Transcriptional regulator
EXW26_RS16890	COG0604	alcohol dehydrogenase
EXW26_RS16895	COG1113	amino acid transport
EXW26_RS16905	COG2814	Major facilitator Superfamily
EXW26_RS16935	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_RS16940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_RS16960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS16965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS16970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS16975	COG3739	integral membrane protein
EXW26_RS17000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS17005	COG0583	DNA-binding transcription factor activity
EXW26_RS17030	COG1193	negative regulation of DNA recombination
EXW26_RS17050	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW26_RS17055	COG1164	Oligoendopeptidase f
EXW26_RS17060	COG2957	Belongs to the agmatine deiminase family
EXW26_RS17080	COG3781	membrane
EXW26_RS17095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_RS17130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW26_RS17135	COG0640	Transcriptional regulator
EXW26_RS17140	COG0604	alcohol dehydrogenase
EXW26_RS17145	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW26_RS17155	COG0457	Tetratricopeptide repeat
EXW26_RS17160	COG2808	Putative FMN-binding domain
EXW26_RS17170	COG0277	FAD linked oxidase domain protein
EXW26_RS17190	COG1285	pathogenesis
EXW26_RS17200	COG2514	catechol 2,3-dioxygenase activity
EXW26_RS17205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS17210	COG1126	abc transporter atp-binding protein
EXW26_RS17215	COG0765	amino acid transport
EXW26_RS17220	COG2720	vancomycin resistance protein
EXW26_RS17245	COG1278	Cold shock
EXW26_RS17255	COG0716	FMN binding
EXW26_RS17265	COG0494	nUDIX hydrolase
EXW26_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS17295	COG0165	Argininosuccinate lyase
EXW26_RS17310	COG4145	pantothenate transmembrane transporter activity
EXW26_RS17320	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS17325	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS17335	COG1657	PFAM Prenyltransferase squalene oxidase
EXW26_RS17340	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW26_RS17345	COG2962	Rard protein
EXW26_RS17350	COG3326	Membrane
EXW26_RS17355	COG0531	amino acid
EXW26_RS17385	COG2226	methyltransferase
EXW26_RS17390	COG4166	transmembrane transport
EXW26_RS17395	COG4166	transmembrane transport
EXW26_RS17400	COG4166	transmembrane transport
EXW26_RS17410	COG1131	(ABC) transporter
EXW26_RS17430	COG0673	inositol 2-dehydrogenase activity
EXW26_RS17435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW26_RS17440	COG0187	DNA topoisomerase II activity
EXW26_RS17445	COG1832	CoA-binding protein
EXW26_RS17450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_RS17455	COG0745	RESPONSE REGULATOR receiver
EXW26_RS17465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW26_RS17465	COG1328	CTP reductase activity
EXW26_RS17475	COG4841	protein insertion into membrane
EXW26_RS17480	COG0824	Thioesterase
EXW26_RS17505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS17520	COG1266	CAAX protease self-immunity
EXW26_RS17525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW26_RS17555	COG2211	Major facilitator Superfamily
EXW26_RS17565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW26_RS17580	COG0183	Belongs to the thiolase family
EXW26_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS17590	COG1268	BioY protein
EXW26_RS17595	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS17600	COG1396	sequence-specific DNA binding
EXW26_RS17640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS17650	COG5002	protein histidine kinase activity
EXW26_RS17660	COG0400	carboxylic ester hydrolase activity
EXW26_RS17665	COG0346	lactoylglutathione lyase activity
EXW26_RS17675	COG0069	glutamate synthase activity
EXW26_RS17680	COG1902	pentaerythritol trinitrate reductase activity
EXW26_RS17685	COG1329	Transcriptional regulator
EXW26_RS17690	COG0010	Belongs to the arginase family
EXW26_RS17700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW26_RS17705	COG2986	histidine ammonia-lyase
EXW26_RS17715	COG2226	methyltransferase
EXW26_RS17740	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW26_RS17745	COG0785	Cytochrome C biogenesis protein
EXW26_RS17755	COG1473	amidohydrolase
EXW26_RS17760	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_RS17765	COG1131	(ABC) transporter
EXW26_RS17775	COG0583	DNA-binding transcription factor activity
EXW26_RS17785	COG1346	cytolysis
EXW26_RS17800	COG0730	response to heat
EXW26_RS17810	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_RS17810	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS17830	COG1132	(ABC) transporter
EXW26_RS17835	COG1132	(ABC) transporter
EXW26_RS17840	COG3763	UPF0154 protein
EXW26_RS17860	COG3639	organic phosphonate transmembrane transporter activity
EXW26_RS17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS17875	COG0737	Belongs to the 5'-nucleotidase family
EXW26_RS17885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW26_RS17890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW26_RS17905	COG1695	Transcriptional regulator
EXW26_RS17910	COG1132	(ABC) transporter
EXW26_RS17945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_RS17955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW26_RS17960	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW26_RS17960	COG3420	alginic acid biosynthetic process
EXW26_RS17990	COG1216	Glycosyl transferase, family 2
EXW26_RS18010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_RS18010	COG0463	Glycosyl transferase, family 2
EXW26_RS18015	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS18020	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS18025	COG1086	Polysaccharide biosynthesis protein
EXW26_RS18030	COG0489	protein tyrosine kinase activity
EXW26_RS18035	COG3944	biosynthesis protein
EXW26_RS18040	COG0174	glutamine synthetase
EXW26_RS18045	COG0789	Transcriptional regulator
EXW26_RS18050	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW26_RS18055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW26_RS18060	COG2860	membrane
EXW26_RS18070	COG0464	growth
EXW26_RS18090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW26_RS18100	COG1388	LysM domain
EXW26_RS18100	COG3584	3D domain protein
EXW26_RS18105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW26_RS18105	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_RS18105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW26_RS18110	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW26_RS18115	COG1349	DNA-binding transcription factor activity
EXW26_RS18120	COG1979	alcohol dehydrogenase
EXW26_RS18125	COG2322	membrane
EXW26_RS18135	COG1113	amino acid transport
EXW26_RS18145	COG1473	amidohydrolase
EXW26_RS18150	COG1408	metallophosphoesterase
EXW26_RS18155	COG2116	formate transmembrane transporter activity
EXW26_RS18170	COG2217	Heavy metal translocating P-type atpase
EXW26_RS18175	COG2608	mercury ion transmembrane transporter activity
EXW26_RS18180	COG1937	Protein conserved in bacteria
EXW26_RS18210	COG4566	intracellular signal transduction
EXW26_RS18215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW26_RS18220	COG2819	hydrolase of the alpha beta superfamily
EXW26_RS18225	COG1120	ATPase activity
EXW26_RS18230	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS18235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS18240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS18245	COG0708	Exodeoxyribonuclease III
EXW26_RS18250	COG2169	Transcriptional regulator
EXW26_RS18255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW26_RS18260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW26_RS18270	COG2706	6-phosphogluconolactonase activity
EXW26_RS18275	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_RS18280	COG2364	Membrane
EXW26_RS18300	COG0346	lactoylglutathione lyase activity
EXW26_RS18305	COG3300	MHYT domain
EXW26_RS18305	COG5001	Diguanylate cyclase
EXW26_RS18345	COG1346	cytolysis
EXW26_RS18355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW26_RS18360	COG0596	Alpha beta hydrolase
EXW26_RS18360	COG2945	thiolester hydrolase activity
EXW26_RS18365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW26_RS18375	COG2188	Transcriptional regulator
EXW26_RS18380	COG2723	6-phospho-beta-galactosidase activity
EXW26_RS18385	COG0840	transmembrane signaling receptor activity
EXW26_RS18395	COG3773	Cell wall hydrolase
EXW26_RS18405	COG1368	sulfuric ester hydrolase activity
EXW26_RS18410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW26_RS18420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW26_RS18425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW26_RS18430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW26_RS18440	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW26_RS18445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW26_RS18450	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW26_RS18455	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW26_RS18455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW26_RS18465	COG2359	stage V sporulation protein S
EXW26_RS18470	COG1692	metallophosphoesterase
EXW26_RS18475	COG1418	mRNA catabolic process
EXW26_RS18480	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW26_RS18485	COG1546	Belongs to the CinA family
EXW26_RS18485	COG1058	Belongs to the CinA family
EXW26_RS18490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW26_RS18495	COG1426	Protein conserved in bacteria
EXW26_RS18510	COG0300	oxidoreductase activity
EXW26_RS18515	COG0612	Peptidase, M16
EXW26_RS18520	COG0612	Peptidase, M16
EXW26_RS18525	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW26_RS18530	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW26_RS18535	COG3845	ABC transporter
EXW26_RS18540	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW26_RS18545	COG2188	Transcriptional regulator
EXW26_RS18550	COG1674	ftsk spoiiie
EXW26_RS18560	COG0740	serine-type endopeptidase activity
EXW26_RS18565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW26_RS18575	COG0527	aspartate kinase activity
EXW26_RS18580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW26_RS18585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW26_RS18590	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW26_RS18595	COG1873	PFAM PRC-barrel domain
EXW26_RS18600	COG0612	Peptidase, M16
EXW26_RS18605	COG0726	polysaccharide deacetylase
EXW26_RS18610	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW26_RS18620	COG0196	riboflavin kinase activity
EXW26_RS18630	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW26_RS18635	COG1550	Protein conserved in bacteria
EXW26_RS18640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW26_RS18645	COG1358	cellular component organization or biogenesis
EXW26_RS18650	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW26_RS18655	COG0195	Participates in both transcription termination and antitermination
EXW26_RS18660	COG0779	Required for maturation of 30S ribosomal subunits
EXW26_RS18670	COG0442	prolyl-tRNA aminoacylation
EXW26_RS18675	COG0750	zinc metalloprotease
EXW26_RS18685	COG4589	Belongs to the CDS family
EXW26_RS18695	COG0233	cytoplasmic translational termination
EXW26_RS18700	COG0528	UMP kinase activity
EXW26_RS18705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW26_RS18710	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW26_RS18715	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW26_RS18720	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW26_RS18725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW26_RS18730	COG4974	Belongs to the 'phage' integrase family
EXW26_RS18735	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW26_RS18740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW26_RS18745	COG0758	DNA mediated transformation
EXW26_RS18750	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW26_RS18755	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW26_RS18760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW26_RS18775	COG0335	large ribosomal subunit rRNA binding
EXW26_RS18780	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW26_RS18785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW26_RS18790	COG1837	Belongs to the UPF0109 family
EXW26_RS18800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW26_RS18805	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EXW26_RS18810	COG0552	protein localization to endoplasmic reticulum
EXW26_RS18815	COG1196	nuclear chromosome segregation
EXW26_RS18820	COG0571	ribonuclease III activity
EXW26_RS18825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_RS18830	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS18835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW26_RS18840	COG0416	fatty acid biosynthetic process
EXW26_RS18845	COG2050	protein possibly involved in aromatic compounds catabolism
EXW26_RS18845	COG1349	DNA-binding transcription factor activity
EXW26_RS18850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW26_RS18855	COG1461	Dihydroxyacetone kinase
EXW26_RS18860	COG1302	Protein conserved in bacteria
EXW26_RS18875	COG1564	THIamine pyrophosphokinase
EXW26_RS18880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW26_RS18890	COG2815	serine threonine protein kinase
EXW26_RS18890	COG0515	serine threonine protein kinase
EXW26_RS18895	COG0631	protein serine/threonine phosphatase activity
EXW26_RS18900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW26_RS18905	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW26_RS18905	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW26_RS18910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW26_RS18915	COG0242	peptide deformylase activity
EXW26_RS18920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW26_RS18925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW26_RS18930	COG1758	RNA polymerase activity
EXW26_RS18945	COG1561	YicC-like family, N-terminal region
EXW26_RS18950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW26_RS18965	COG0006	proline dipeptidase activity
EXW26_RS19010	COG0167	dihydroorotate dehydrogenase activity
EXW26_RS19015	COG0543	2 iron, 2 sulfur cluster binding
EXW26_RS19020	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW26_RS19030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW26_RS19035	COG0540	Belongs to the ATCase OTCase family
EXW26_RS19045	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW26_RS19050	COG0564	pseudouridine synthase activity
EXW26_RS19055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW26_RS19065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW26_RS19070	COG3599	regulation of cell shape
EXW26_RS19075	COG2302	S4 RNA-binding domain
EXW26_RS19080	COG0762	integral membrane protein
EXW26_RS19085	COG1799	cell septum assembly
EXW26_RS19090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW26_RS19100	COG1873	PFAM PRC-barrel domain
EXW26_RS19105	COG1191	sigma factor activity
EXW26_RS19110	COG1191	sigma factor activity
EXW26_RS19120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW26_RS19125	COG0849	cell division
EXW26_RS19130	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW26_RS19145	COG0772	Belongs to the SEDS family
EXW26_RS19150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW26_RS19155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW26_RS19160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW26_RS19165	COG0768	penicillin binding
EXW26_RS19170	COG0768	penicillin binding
EXW26_RS19180	COG0275	rRNA processing
EXW26_RS19185	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW26_RS19190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW26_RS19195	COG0454	-acetyltransferase
EXW26_RS19205	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW26_RS19210	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW26_RS19215	COG1323	Belongs to the UPF0348 family
EXW26_RS19220	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW26_RS19225	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW26_RS19230	COG3314	Sporulation integral membrane protein YlbJ
EXW26_RS19235	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW26_RS19240	COG0742	ribosomal rna small subunit methyltransferase
EXW26_RS19250	COG4471	UPF0298 protein
EXW26_RS19255	COG3679	Belongs to the UPF0342 family
EXW26_RS19260	COG0406	alpha-ribazole phosphatase activity
EXW26_RS19275	COG2340	Cysteine-rich secretory protein family
EXW26_RS19285	COG3336	cytochrome c oxidase
EXW26_RS19310	COG0109	protoheme IX farnesyltransferase activity
EXW26_RS19315	COG1612	heme a metabolic process
EXW26_RS19320	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW26_RS19325	COG0772	Belongs to the SEDS family
EXW26_RS19330	COG4838	Belongs to the UPF0358 family
EXW26_RS19335	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW26_RS19340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW26_RS19350	COG4896	Protein conserved in bacteria
EXW26_RS19365	COG1217	gtp-binding protein TYPA
EXW26_RS19375	COG0483	inositol monophosphate 1-phosphatase activity
EXW26_RS19385	COG4493	Belongs to the UPF0637 family
EXW26_RS19390	COG4476	Belongs to the UPF0223 family
EXW26_RS19395	COG1982	Orn Lys Arg decarboxylase major
EXW26_RS19440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_RS19445	COG0022	dehydrogenase e1 component
EXW26_RS19450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW26_RS19465	COG0561	phosphatase activity
EXW26_RS19470	COG5503	Protein of unknown function (DUF1447)
EXW26_RS19475	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW26_RS19480	COG0569	domain protein
EXW26_RS19490	COG1473	amidohydrolase
EXW26_RS19495	COG2171	N-acyltransferase activity
EXW26_RS19500	COG0583	DNA-binding transcription factor activity
EXW26_RS19505	COG0517	IMP dehydrogenase activity
EXW26_RS19515	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW26_RS19525	COG4703	Protein of unknown function (DUF1797)
EXW26_RS19540	COG2200	EAL domain
EXW26_RS19545	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS19550	COG1408	metallophosphoesterase
EXW26_RS19595	COG2814	Major facilitator Superfamily
EXW26_RS19605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW26_RS19615	COG3209	COG3209 Rhs family protein
EXW26_RS19625	COG2205	protein histidine kinase activity
EXW26_RS19635	COG0436	Aminotransferase
EXW26_RS19640	COG1609	Transcriptional regulator
EXW26_RS19645	COG3833	ABC-type maltose transport systems, permease component
EXW26_RS19650	COG1175	transmembrane transport
EXW26_RS19655	COG2182	Extracellular solute-binding protein
EXW26_RS19665	COG0366	Alpha amylase catalytic
EXW26_RS19670	COG3842	ATPase activity
EXW26_RS19710	COG0183	Belongs to the thiolase family
EXW26_RS19745	COG1695	Transcriptional regulator
EXW26_RS19750	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS19760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW26_RS19765	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW26_RS19770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW26_RS19775	COG0436	Aminotransferase
EXW26_RS19780	COG1850	ribulose-bisphosphate carboxylase activity
EXW26_RS19785	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW26_RS19790	COG0235	Class ii aldolase
EXW26_RS19795	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW26_RS19810	COG2084	Dehydrogenase
EXW26_RS19820	COG2199	diguanylate cyclase activity
EXW26_RS19825	COG0778	Nitroreductase
EXW26_RS19850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW26_RS19850	COG2190	(PTS) system
EXW26_RS19850	COG1263	PTS System
EXW26_RS19855	COG3711	transcriptional antiterminator
EXW26_RS19865	COG2188	Transcriptional regulator
EXW26_RS19870	COG0363	glucosamine-6-phosphate deaminase activity
EXW26_RS19875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW26_RS19885	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW26_RS19890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW26_RS19900	COG1547	Domain of unknown function (DUF309)
EXW26_RS19910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW26_RS19915	COG4086	secreted protein
EXW26_RS19920	COG0561	phosphatase activity
EXW26_RS19925	COG0697	spore germination
EXW26_RS19940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS19965	COG0733	neurotransmitter:sodium symporter activity
EXW26_RS19985	COG1686	Belongs to the peptidase S11 family
EXW26_RS19990	COG1725	Transcriptional regulator
EXW26_RS19995	COG1131	(ABC) transporter
EXW26_RS20015	COG1846	Transcriptional regulator
EXW26_RS20030	COG0598	Magnesium transport protein CorA
EXW26_RS20045	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW26_RS20055	COG4974	Belongs to the 'phage' integrase family
EXW26_RS20065	COG0735	belongs to the Fur family
EXW26_RS20070	COG1300	Membrane
EXW26_RS20090	COG0667	Aldo Keto reductase
EXW26_RS20095	COG0656	L-ascorbic acid biosynthetic process
EXW26_RS20100	COG0456	acetyltransferase
EXW26_RS20100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW26_RS20110	COG4085	toxin activity
EXW26_RS20110	COG0737	Belongs to the 5'-nucleotidase family
EXW26_RS20110	COG1525	nuclease
EXW26_RS20115	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW26_RS20125	COG0596	Alpha beta hydrolase
EXW26_RS20130	COG2056	Na+-H+ antiporter family
EXW26_RS20135	COG1609	Transcriptional regulator
EXW26_RS20140	COG0456	acetyltransferase
EXW26_RS20145	COG1073	alpha beta
EXW26_RS20160	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW26_RS20160	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW26_RS20165	COG0307	riboflavin synthase, alpha
EXW26_RS20170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW26_RS20170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW26_RS20185	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW26_RS20190	COG4106	trans-aconitate 2-methyltransferase activity
EXW26_RS20195	COG1073	alpha beta
EXW26_RS20195	COG2226	methyltransferase
EXW26_RS20200	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_RS20210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW26_RS20220	COG1757	Na H antiporter
EXW26_RS20225	COG0737	Belongs to the 5'-nucleotidase family
EXW26_RS20235	COG1522	sequence-specific DNA binding
EXW26_RS20260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW26_RS20270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW26_RS20280	COG0300	oxidoreductase activity
EXW26_RS20285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS20290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_RS20295	COG1760	l-serine dehydratase
EXW26_RS20300	COG1760	l-serine dehydratase
EXW26_RS20310	COG1234	tRNA 3'-trailer cleavage
EXW26_RS20345	COG1131	(ABC) transporter
EXW26_RS20360	COG1285	pathogenesis
EXW26_RS20375	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW26_RS20380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS20395	COG1376	ErfK ybiS ycfS ynhG family protein
EXW26_RS20400	COG4129	membrane
EXW26_RS20405	COG1126	abc transporter atp-binding protein
EXW26_RS20410	COG0765	amino acid transport
EXW26_RS20415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW26_RS20430	COG2323	membrane
EXW26_RS20435	COG0772	Belongs to the SEDS family
EXW26_RS20440	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW26_RS20445	COG0022	dehydrogenase e1 component
EXW26_RS20450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW26_RS20455	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW26_RS20460	COG3426	butyrate kinase activity
EXW26_RS20470	COG0280	phosphate acetyltransferase
EXW26_RS20475	COG3290	protein histidine kinase activity
EXW26_RS20475	COG3829	transcription factor binding
EXW26_RS20485	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_RS20490	COG3093	addiction module antidote protein HigA
EXW26_RS20500	COG0745	RESPONSE REGULATOR receiver
EXW26_RS20505	COG0750	zinc metalloprotease
EXW26_RS20510	COG0497	DNA recombination
EXW26_RS20515	COG1438	arginine binding
EXW26_RS20520	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW26_RS20525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW26_RS20530	COG0142	geranyltranstransferase activity
EXW26_RS20535	COG1722	exodeoxyribonuclease VII activity
EXW26_RS20540	COG1570	exodeoxyribonuclease VII activity
EXW26_RS20545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW26_RS20550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW26_RS20555	COG1302	Protein conserved in bacteria
EXW26_RS20560	COG0439	Biotin carboxylase
EXW26_RS20565	COG0511	ligase activity, forming carbon-carbon bonds
EXW26_RS20610	COG3854	ATPases associated with a variety of cellular activities
EXW26_RS20630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW26_RS20635	COG0006	proline dipeptidase activity
EXW26_RS20640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW26_RS20650	COG3872	metal-dependent enzyme
EXW26_RS20660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW26_RS20665	COG1321	iron dependent repressor
EXW26_RS20695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS20705	COG1609	Transcriptional regulator
EXW26_RS20715	COG2076	Multidrug Resistance protein
EXW26_RS20720	COG2076	Multidrug Resistance protein
EXW26_RS20755	COG1725	Transcriptional regulator
EXW26_RS20770	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW26_RS20775	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW26_RS20780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW26_RS20785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_RS20810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW26_RS20835	COG4970	Tfp pilus assembly protein FimT
EXW26_RS20845	COG1459	type II secretion system
EXW26_RS20850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW26_RS20905	COG0646	methionine synthase
EXW26_RS20905	COG1410	methionine synthase
EXW26_RS20910	COG0646	methionine synthase
EXW26_RS20910	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW26_RS20915	COG0626	cystathionine gamma-synthase activity
EXW26_RS20920	COG0626	cystathionine gamma-synthase activity
EXW26_RS20935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS20945	COG1940	carbohydrate kinase activity
EXW26_RS20950	COG4483	Protein conserved in bacteria
EXW26_RS20955	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW26_RS20960	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW26_RS20965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW26_RS20970	COG0704	Plays a role in the regulation of phosphate uptake
EXW26_RS20985	COG0581	inorganic phosphate transmembrane transporter activity
EXW26_RS20990	COG0573	inorganic phosphate transmembrane transporter activity
EXW26_RS20995	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW26_RS21000	COG0768	penicillin binding
EXW26_RS21005	COG0477	Major facilitator Superfamily
EXW26_RS21010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_RS21030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW26_RS21035	COG0735	belongs to the Fur family
EXW26_RS21040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW26_RS21045	COG1121	(ABC) transporter
EXW26_RS21050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS21060	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW26_RS21075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW26_RS21080	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW26_RS21085	COG2384	SAM-dependent methyltransferase
EXW26_RS21095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW26_RS21100	COG0358	DNA primase activity
EXW26_RS21110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW26_RS21115	COG0517	IMP dehydrogenase activity
EXW26_RS21120	COG1381	Involved in DNA repair and RecF pathway recombination
EXW26_RS21130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW26_RS21135	COG0295	cytidine deaminase activity
EXW26_RS21140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW26_RS21145	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW26_RS21150	COG1480	7TM receptor with intracellular HD hydrolase
EXW26_RS21155	COG1702	phosphate starvation-inducible protein PhoH
EXW26_RS21170	COG1610	YqeY-like protein
EXW26_RS21175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW26_RS21180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW26_RS21185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW26_RS21195	COG0484	heat shock protein binding
EXW26_RS21200	COG0443	Heat shock 70 kDa protein
EXW26_RS21210	COG1420	regulation of RNA biosynthetic process
EXW26_RS21215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW26_RS21220	COG1733	regulation of RNA biosynthetic process
EXW26_RS21225	COG0481	GTPase activity
EXW26_RS21235	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW26_RS21240	COG0268	Binds directly to 16S ribosomal RNA
EXW26_RS21245	COG1466	dna polymerase III delta subunit
EXW26_RS21255	COG0658	competence protein
EXW26_RS21255	COG2333	competence protein COMEC
EXW26_RS21260	COG2131	deaminase
EXW26_RS21265	COG1555	photosystem II stabilization
EXW26_RS21265	COG1596	polysaccharide export
EXW26_RS21270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW26_RS21275	COG2226	methyltransferase
EXW26_RS21280	COG0799	negative regulation of ribosome biogenesis
EXW26_RS21285	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW26_RS21290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW26_RS21295	COG1534	Rna-binding protein
EXW26_RS21300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW26_RS21305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW26_RS21310	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW26_RS21320	COG0688	phosphatidylethanolamine metabolic process
EXW26_RS21330	COG1595	DNA-templated transcription, initiation
EXW26_RS21335	COG2357	RelA SpoT domain protein
EXW26_RS21345	COG1785	Belongs to the alkaline phosphatase family
EXW26_RS21355	COG2267	carboxylic ester hydrolase activity
EXW26_RS21390	COG1404	Belongs to the peptidase S8 family
EXW26_RS21395	COG3186	Phenylalanine-4-hydroxylase
EXW26_RS21400	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW26_RS21405	COG2514	catechol 2,3-dioxygenase activity
EXW26_RS21410	COG2259	Doxx family
EXW26_RS21450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS21460	COG1454	alcohol dehydrogenase
EXW26_RS21460	COG1012	belongs to the aldehyde dehydrogenase family
EXW26_RS21465	COG0626	cystathionine gamma-synthase activity
EXW26_RS21470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_RS21475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW26_RS21480	COG2226	methyltransferase
EXW26_RS21495	COG0768	penicillin binding
EXW26_RS21500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW26_RS21505	COG0572	uridine kinase
EXW26_RS21510	COG0826	peptidase U32
EXW26_RS21515	COG0826	peptidase U32
EXW26_RS21520	COG4122	O-methyltransferase activity
EXW26_RS21525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW26_RS21535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW26_RS21540	COG4472	Bacterial protein of unknown function (DUF965)
EXW26_RS21545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW26_RS21555	COG0628	permease
EXW26_RS21575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW26_RS21585	COG0482	sulfurtransferase activity
EXW26_RS21590	COG1104	cysteine desulfurase activity
EXW26_RS21595	COG1959	2 iron, 2 sulfur cluster binding
EXW26_RS21600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW26_RS21610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW26_RS21615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW26_RS21630	COG1490	D-aminoacyl-tRNA deacylase activity
EXW26_RS21635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW26_RS21640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW26_RS21645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW26_RS21645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW26_RS21650	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW26_RS21655	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW26_RS21655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW26_RS21665	COG2244	polysaccharide biosynthetic process
EXW26_RS21670	COG2323	membrane
EXW26_RS21680	COG1862	Preprotein translocase
EXW26_RS21685	COG0343	queuine tRNA-ribosyltransferase activity
EXW26_RS21690	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW26_RS21700	COG2255	four-way junction helicase activity
EXW26_RS21705	COG0632	four-way junction helicase activity
EXW26_RS21710	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW26_RS21735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW26_RS21740	COG0157	Belongs to the NadC ModD family
EXW26_RS21745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW26_RS21750	COG1104	cysteine desulfurase activity
EXW26_RS21755	COG1827	regulation of RNA biosynthetic process
EXW26_RS21760	COG2258	MOSC domain
EXW26_RS21765	COG0077	Prephenate dehydratase
EXW26_RS21770	COG0577	efflux transmembrane transporter activity
EXW26_RS21775	COG0577	efflux transmembrane transporter activity
EXW26_RS21780	COG1136	(ABC) transporter
EXW26_RS21785	COG5002	protein histidine kinase activity
EXW26_RS21790	COG0745	RESPONSE REGULATOR receiver
EXW26_RS21795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW26_RS21800	COG3290	protein histidine kinase activity
EXW26_RS21810	COG2868	ribosomal protein
EXW26_RS21820	COG1530	ribonuclease E activity
EXW26_RS21825	COG1994	Peptidase M50
EXW26_RS21830	COG0739	heme binding
EXW26_RS21835	COG2894	cell division
EXW26_RS21840	COG0850	regulation of cytokinetic process
EXW26_RS21855	COG1077	Cell shape determining protein MreB Mrl
EXW26_RS21860	COG2003	Belongs to the UPF0758 family
EXW26_RS21865	COG0424	maF-like protein
EXW26_RS21875	COG0285	dihydrofolate synthase activity
EXW26_RS21890	COG1388	LysM domain
EXW26_RS21895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW26_RS21900	COG0113	porphobilinogen synthase activity
EXW26_RS21905	COG1587	Uroporphyrinogen-III synthase
EXW26_RS21910	COG0181	hydroxymethylbilane synthase activity
EXW26_RS21915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW26_RS21920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW26_RS21925	COG1846	Transcriptional regulator
EXW26_RS21930	COG1764	response to oxidative stress
EXW26_RS21935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW26_RS21945	COG0470	DNA polymerase III
EXW26_RS21945	COG1067	ATP-dependent peptidase activity
EXW26_RS21955	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW26_RS21985	COG0622	Phosphoesterase
EXW26_RS21995	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW26_RS22000	COG5401	PFAM Sporulation and spore germination
EXW26_RS22010	COG0477	Major facilitator Superfamily
EXW26_RS22020	COG1309	transcriptional regulator
EXW26_RS22030	COG2197	response regulator
EXW26_RS22035	COG2233	PERMEase
EXW26_RS22040	COG0402	S-adenosylhomocysteine deaminase activity
EXW26_RS22045	COG1983	PspC domain protein
EXW26_RS22050	COG1396	sequence-specific DNA binding
EXW26_RS22055	COG0697	spore germination
EXW26_RS22065	COG1959	2 iron, 2 sulfur cluster binding
EXW26_RS22070	COG1668	transmembrane transport
EXW26_RS22075	COG4152	abc transporter atp-binding protein
EXW26_RS22080	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW26_RS22085	COG1360	Flagellar Motor Protein
EXW26_RS22090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW26_RS22095	COG1876	peptidase activity
EXW26_RS22100	COG0824	Thioesterase
EXW26_RS22105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW26_RS22110	COG1053	succinate dehydrogenase
EXW26_RS22115	COG2009	succinate dehydrogenase
EXW26_RS22120	COG1719	4-vinyl reductase, 4VR
EXW26_RS22125	COG0322	excinuclease ABC activity
EXW26_RS22130	COG3118	belongs to the thioredoxin family
EXW26_RS22135	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW26_RS22140	COG2086	electron transfer activity
EXW26_RS22145	COG1024	Enoyl-CoA hydratase
EXW26_RS22150	COG1309	transcriptional regulator
EXW26_RS22155	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS22180	COG2318	DinB family
EXW26_RS22210	COG1131	(ABC) transporter
EXW26_RS22215	COG2205	protein histidine kinase activity
EXW26_RS22220	COG0745	RESPONSE REGULATOR receiver
EXW26_RS22230	COG4895	conserved protein (DUF2196)
EXW26_RS22235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW26_RS22240	COG2329	Antibiotic biosynthesis monooxygenase
EXW26_RS22245	COG4509	Sortase family
EXW26_RS22250	COG1120	ATPase activity
EXW26_RS22265	COG5386	Cell surface protein
EXW26_RS22275	COG5386	Cell surface protein
EXW26_RS22280	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS22290	COG1193	negative regulation of DNA recombination
EXW26_RS22295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW26_RS22295	COG1796	DNA polymerase
EXW26_RS22300	COG1286	toxin biosynthetic process
EXW26_RS22305	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW26_RS22310	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW26_RS22335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW26_RS22340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW26_RS22350	COG1418	mRNA catabolic process
EXW26_RS22380	COG2814	Major facilitator Superfamily
EXW26_RS22385	COG1566	PFAM secretion protein HlyD family protein
EXW26_RS22390	COG1309	transcriptional regulator
EXW26_RS22395	COG1363	Peptidase, m42
EXW26_RS22405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW26_RS22420	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW26_RS22430	COG1484	DNA-dependent DNA replication
EXW26_RS22435	COG3611	Membrane attachment protein
EXW26_RS22440	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW26_RS22445	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW26_RS22450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW26_RS22455	COG0237	dephospho-CoA kinase activity
EXW26_RS22460	COG1971	Probably functions as a manganese efflux pump
EXW26_RS22470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_RS22470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW26_RS22475	COG5002	protein histidine kinase activity
EXW26_RS22480	COG0745	RESPONSE REGULATOR receiver
EXW26_RS22495	COG0039	L-malate dehydrogenase activity
EXW26_RS22500	COG0538	isocitrate dehydrogenase activity
EXW26_RS22505	COG0372	Belongs to the citrate synthase family
EXW26_RS22515	COG0628	permease
EXW26_RS22520	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW26_RS22530	COG0205	6-phosphofructokinase activity
EXW26_RS22540	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW26_RS22545	COG1725	Transcriptional regulator
EXW26_RS22550	COG0281	malic enzyme
EXW26_RS22555	COG0587	DNA-directed DNA polymerase activity
EXW26_RS22570	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW26_RS22585	COG4109	DRTGG domain
EXW26_RS22595	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW26_RS22600	COG0006	proline dipeptidase activity
EXW26_RS22645	COG0662	Cupin 2, conserved barrel domain protein
EXW26_RS22655	COG1476	TRANSCRIPTIONal
EXW26_RS22670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW26_RS22675	COG0589	response to stress
EXW26_RS22695	COG0165	Argininosuccinate lyase
EXW26_RS22700	COG0137	argininosuccinate synthase activity
EXW26_RS22715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS22730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW26_RS22735	COG0827	DNA restriction-modification system
EXW26_RS22740	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW26_RS22745	COG3874	Sporulation protein YtfJ
EXW26_RS22760	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW26_RS22770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_RS22785	COG1104	cysteine desulfurase activity
EXW26_RS22790	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW26_RS22805	COG1309	transcriptional regulator
EXW26_RS22810	COG1956	GAF domain-containing protein
EXW26_RS22815	COG0626	cystathionine gamma-synthase activity
EXW26_RS22820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW26_RS22850	COG1595	DNA-templated transcription, initiation
EXW26_RS22860	COG0110	maltose O-acetyltransferase activity
EXW26_RS22865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW26_RS22870	COG0454	-acetyltransferase
EXW26_RS22875	COG0517	IMP dehydrogenase activity
EXW26_RS22880	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW26_RS22895	COG0745	RESPONSE REGULATOR receiver
EXW26_RS22900	COG5002	protein histidine kinase activity
EXW26_RS22905	COG0666	response to abiotic stimulus
EXW26_RS22915	COG1970	mechanosensitive ion channel activity
EXW26_RS22940	COG1609	Transcriptional regulator
EXW26_RS22955	COG4851	CamS sex pheromone cAM373 precursor
EXW26_RS22960	COG3118	belongs to the thioredoxin family
EXW26_RS22970	COG2309	aminopeptidase activity
EXW26_RS22995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS23000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW26_RS23010	COG1674	ftsk spoiiie
EXW26_RS23025	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_RS23030	COG4848	Belongs to the UPF0354 family
EXW26_RS23035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS23040	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW26_RS23045	COG1363	Peptidase, m42
EXW26_RS23055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS23060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW26_RS23070	COG0510	thiamine kinase activity
EXW26_RS23075	COG1523	belongs to the glycosyl hydrolase 13 family
EXW26_RS23085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW26_RS23090	COG1349	DNA-binding transcription factor activity
EXW26_RS23095	COG1187	pseudouridine synthase activity
EXW26_RS23100	COG2244	polysaccharide biosynthetic process
EXW26_RS23105	COG2081	HI0933 family
EXW26_RS23110	COG2814	Major facilitator Superfamily
EXW26_RS23120	COG3832	glyoxalase III activity
EXW26_RS23140	COG1329	Transcriptional regulator
EXW26_RS23165	COG0314	molybdopterin synthase activity
EXW26_RS23170	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW26_RS23175	COG0303	'Molybdopterin
EXW26_RS23180	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW26_RS23185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW26_RS23190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW26_RS23210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS23220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW26_RS23260	COG0495	leucyl-tRNA aminoacylation
EXW26_RS23265	COG2814	Major facilitator Superfamily
EXW26_RS23270	COG0475	glutathione-regulated potassium exporter activity
EXW26_RS23275	COG0490	domain, Protein
EXW26_RS23280	COG0582	viral genome integration into host DNA
EXW26_RS23290	COG1136	(ABC) transporter
EXW26_RS23310	COG1242	4 iron, 4 sulfur cluster binding
EXW26_RS23315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW26_RS23320	COG1794	racemase activity, acting on amino acids and derivatives
EXW26_RS23335	COG2267	carboxylic ester hydrolase activity
EXW26_RS23340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW26_RS23345	COG0671	phosphoesterase, PA-phosphatase related
EXW26_RS23350	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS23375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW26_RS23380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW26_RS23405	COG5002	protein histidine kinase activity
EXW26_RS23410	COG3852	Histidine kinase
EXW26_RS23415	COG0753	catalase activity
EXW26_RS23420	COG2267	carboxylic ester hydrolase activity
EXW26_RS23425	COG1368	sulfuric ester hydrolase activity
EXW26_RS23430	COG4895	conserved protein (DUF2196)
EXW26_RS23445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW26_RS23450	COG1116	anion transmembrane transporter activity
EXW26_RS23455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW26_RS23480	COG0494	nUDIX hydrolase
EXW26_RS23515	COG2076	Multidrug Resistance protein
EXW26_RS23525	COG0789	Transcriptional regulator
EXW26_RS23530	COG1854	S-ribosylhomocysteine lyase activity
EXW26_RS23540	COG0288	reversible hydration of carbon dioxide
EXW26_RS23545	COG1271	oxidase subunit
EXW26_RS23550	COG1294	oxidase, subunit
EXW26_RS23565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS23590	COG1842	Phage shock protein A
EXW26_RS23620	COG5002	protein histidine kinase activity
EXW26_RS23625	COG0745	RESPONSE REGULATOR receiver
EXW26_RS23650	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW26_RS23655	COG1597	lipid kinase activity
EXW26_RS23670	COG1136	(ABC) transporter
EXW26_RS23700	COG5002	protein histidine kinase activity
EXW26_RS23710	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS23725	COG0577	efflux transmembrane transporter activity
EXW26_RS23730	COG1136	(ABC) transporter
EXW26_RS23735	COG2207	Transcriptional regulator
EXW26_RS23735	COG3708	Transcriptional regulator
EXW26_RS23745	COG1131	(ABC) transporter
EXW26_RS23750	COG5658	integral membrane protein
EXW26_RS23755	COG0640	Transcriptional regulator
EXW26_RS23760	COG0745	RESPONSE REGULATOR receiver
EXW26_RS23765	COG2205	protein histidine kinase activity
EXW26_RS23770	COG0577	efflux transmembrane transporter activity
EXW26_RS23775	COG0577	efflux transmembrane transporter activity
EXW26_RS23780	COG1136	(ABC) transporter
EXW26_RS23785	COG0577	efflux transmembrane transporter activity
EXW26_RS23800	COG2188	Transcriptional regulator
EXW26_RS23820	COG3964	amidohydrolase
EXW26_RS23840	COG4948	Mandelate Racemase Muconate Lactonizing
EXW26_RS23845	COG0318	PFAM AMP-dependent synthetase and ligase
EXW26_RS23850	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW26_RS23855	COG0596	Alpha beta hydrolase
EXW26_RS23860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW26_RS23865	COG1169	isochorismate synthase
EXW26_RS23870	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW26_RS23875	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW26_RS23880	COG1278	Cold shock
EXW26_RS23900	COG0058	SHG alpha-glucan phosphorylase activity
EXW26_RS23910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW26_RS23915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW26_RS23920	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW26_RS23935	COG1309	transcriptional regulator
EXW26_RS24075	COG1285	pathogenesis
EXW26_RS24080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW26_RS24090	COG0166	Belongs to the GPI family
EXW26_RS24095	COG2155	Conserved Protein
EXW26_RS24100	COG1098	S1 RNA binding domain
EXW26_RS24105	COG0436	Aminotransferase
EXW26_RS24110	COG1522	sequence-specific DNA binding
EXW26_RS24115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW26_RS24120	COG2267	carboxylic ester hydrolase activity
EXW26_RS24130	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW26_RS24150	COG5018	Exonuclease
EXW26_RS24155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_RS24175	COG2050	protein possibly involved in aromatic compounds catabolism
EXW26_RS24185	COG1268	BioY protein
EXW26_RS24190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_RS24195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW26_RS24205	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW26_RS24210	COG3584	3D domain protein
EXW26_RS24225	COG1252	NADH dehydrogenase
EXW26_RS24230	COG0492	ferredoxin-NADP+ reductase activity
EXW26_RS24250	COG1683	Conserved Protein
EXW26_RS24270	COG0316	Belongs to the HesB IscA family
EXW26_RS24275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW26_RS24280	COG4844	belongs to the
EXW26_RS24285	COG1252	NADH dehydrogenase
EXW26_RS24295	COG0390	transport system, permease component
EXW26_RS24300	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW26_RS24330	COG4837	Protein of unknown function (DUF1462)
EXW26_RS24335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW26_RS24345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW26_RS24350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW26_RS24370	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW26_RS24380	COG0647	UMP catabolic process
EXW26_RS24390	COG2445	Protein of unknown function DUF86
EXW26_RS24395	COG1494	fructose-1,6-bisphosphatase
EXW26_RS24410	COG4470	Protein conserved in bacteria
EXW26_RS24420	COG0789	Transcriptional regulator
EXW26_RS24425	COG4377	Putative membrane peptidase family (DUF2324)
EXW26_RS24445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW26_RS24450	COG0739	heme binding
EXW26_RS24460	COG3377	Domain of unknown function (DUF1805)
EXW26_RS24465	COG0737	Belongs to the 5'-nucleotidase family
EXW26_RS24470	COG1695	Transcriptional regulator
EXW26_RS24480	COG0719	Fe-S assembly protein
EXW26_RS24485	COG0822	iron-sulfur transferase activity
EXW26_RS24490	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW26_RS24495	COG0719	Fe-S assembly protein
EXW26_RS24500	COG0396	ATPase activity
EXW26_RS24505	COG1464	Belongs to the NlpA lipoprotein family
EXW26_RS24510	COG1464	Belongs to the NlpA lipoprotein family
EXW26_RS24515	COG2011	ABC-type metal ion transport system permease component
EXW26_RS24520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW26_RS24530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW26_RS24535	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW26_RS24540	COG0509	glycine decarboxylation via glycine cleavage system
EXW26_RS24545	COG1393	Belongs to the ArsC family
EXW26_RS24590	COG1309	transcriptional regulator
EXW26_RS24595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS24600	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS24605	COG0183	Belongs to the thiolase family
EXW26_RS24610	COG1024	Enoyl-CoA hydratase
EXW26_RS24610	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW26_RS24620	COG1686	Belongs to the peptidase S11 family
EXW26_RS24625	COG0506	proline dehydrogenase activity
EXW26_RS24635	COG0011	TIGRFAM Protein of
EXW26_RS24640	COG0840	transmembrane signaling receptor activity
EXW26_RS24655	COG2814	Major facilitator Superfamily
EXW26_RS24660	COG0531	amino acid
EXW26_RS24685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW26_RS24715	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS24725	COG1376	ErfK ybiS ycfS ynhG family protein
EXW26_RS24730	COG0745	RESPONSE REGULATOR receiver
EXW26_RS24735	COG5002	protein histidine kinase activity
EXW26_RS24745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW26_RS24755	COG0840	transmembrane signaling receptor activity
EXW26_RS24760	COG0840	transmembrane signaling receptor activity
EXW26_RS24765	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW26_RS24770	COG3227	Zinc metalloprotease (Elastase)
EXW26_RS24775	COG1741	Belongs to the pirin family
EXW26_RS24790	COG0586	Pfam SNARE associated Golgi protein
EXW26_RS24795	COG0475	glutathione-regulated potassium exporter activity
EXW26_RS24800	COG0490	domain, Protein
EXW26_RS24805	COG1115	amino acid carrier protein
EXW26_RS24810	COG0783	Belongs to the Dps family
EXW26_RS24820	COG2318	DinB family
EXW26_RS24830	COG1611	Belongs to the LOG family
EXW26_RS24840	COG1528	Iron-storage protein
EXW26_RS24845	COG2311	Membrane
EXW26_RS24850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS24855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS24860	COG1115	amino acid carrier protein
EXW26_RS24865	COG1115	amino acid carrier protein
EXW26_RS24870	COG2910	NAD(P)H-binding
EXW26_RS24890	COG0656	L-ascorbic acid biosynthetic process
EXW26_RS24895	COG2814	Major facilitator Superfamily
EXW26_RS24900	COG1733	regulation of RNA biosynthetic process
EXW26_RS24910	COG1252	NADH dehydrogenase
EXW26_RS24930	COG3290	protein histidine kinase activity
EXW26_RS24930	COG0840	transmembrane signaling receptor activity
EXW26_RS24940	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW26_RS24945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW26_RS24960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW26_RS24975	COG4224	UPF0291 protein
EXW26_RS24980	COG1335	isochorismatase
EXW26_RS24985	COG1522	sequence-specific DNA binding
EXW26_RS24995	COG1522	sequence-specific DNA binding
EXW26_RS25000	COG0288	reversible hydration of carbon dioxide
EXW26_RS25005	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW26_RS25010	COG2233	PERMEase
EXW26_RS25050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW26_RS25055	COG0557	exoribonuclease II activity
EXW26_RS25060	COG1647	Serine aminopeptidase, S33
EXW26_RS25065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW26_RS25070	COG1346	cytolysis
EXW26_RS25085	COG0148	phosphopyruvate hydratase activity
EXW26_RS25095	COG0149	triose-phosphate isomerase activity
EXW26_RS25100	COG0126	phosphoglycerate kinase activity
EXW26_RS25105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW26_RS25120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW26_RS25150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS25165	COG2323	membrane
EXW26_RS25175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW26_RS25180	COG1481	regulation of sporulation
EXW26_RS25185	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW26_RS25190	COG1660	Displays ATPase and GTPase activities
EXW26_RS25195	COG1051	belongs to the nudix hydrolase family
EXW26_RS25205	COG0492	ferredoxin-NADP+ reductase activity
EXW26_RS25210	COG0457	Tetratricopeptide repeat
EXW26_RS25215	COG0110	maltose O-acetyltransferase activity
EXW26_RS25220	COG0546	phosphoglycolate phosphatase activity
EXW26_RS25225	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW26_RS25230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW26_RS25235	COG1950	PFAM Membrane protein of
EXW26_RS25240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW26_RS25260	COG0789	Transcriptional regulator
EXW26_RS25295	COG0583	DNA-binding transcription factor activity
EXW26_RS25300	COG0789	Transcriptional regulator
EXW26_RS25305	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW26_RS25310	COG0488	(ABC) transporter
EXW26_RS25320	COG1132	(ABC) transporter
EXW26_RS25325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_RS25330	COG0793	Belongs to the peptidase S41A family
EXW26_RS25330	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_RS25335	COG2177	Part of the ABC transporter FtsEX involved in
EXW26_RS25340	COG2884	Cell division ATP-binding protein ftsE
EXW26_RS25365	COG1131	(ABC) transporter
EXW26_RS25400	COG1278	Cold shock
EXW26_RS25405	COG1040	competence protein
EXW26_RS25410	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW26_RS25415	COG1388	LysM domain
EXW26_RS25415	COG0791	NLP P60 protein
EXW26_RS25420	COG1733	regulation of RNA biosynthetic process
EXW26_RS25425	COG1307	EDD domain protein, DegV family
EXW26_RS25430	COG1739	Uncharacterized protein family UPF0029
EXW26_RS25435	COG1316	TRANSCRIPTIONal
EXW26_RS25440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW26_RS25445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW26_RS25450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW26_RS25460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW26_RS25460	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW26_RS25480	COG1486	melibiose metabolic process
EXW26_RS25485	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_RS25490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_RS25500	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW26_RS25510	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW26_RS25520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW26_RS25525	COG1301	dicarboxylic acid transport
EXW26_RS25540	COG1511	domain protein
EXW26_RS25545	COG0583	DNA-binding transcription factor activity
EXW26_RS25550	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW26_RS25560	COG1271	oxidase subunit
EXW26_RS25565	COG1294	oxidase, subunit
EXW26_RS25570	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW26_RS25575	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW26_RS25580	COG1620	l-lactate permease
EXW26_RS25590	COG2389	metal-binding protein
EXW26_RS25600	COG1368	sulfuric ester hydrolase activity
EXW26_RS25610	COG0791	NLP P60 protein
EXW26_RS25610	COG1388	LysM domain
EXW26_RS25615	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW26_RS25625	COG1215	transferase activity, transferring glycosyl groups
EXW26_RS25630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW26_RS25635	COG3584	3D domain protein
EXW26_RS25635	COG1388	LysM domain
EXW26_RS25660	COG4715	Zinc finger, swim domain protein
EXW26_RS25665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW26_RS25715	COG0577	efflux transmembrane transporter activity
EXW26_RS25720	COG1136	(ABC) transporter
EXW26_RS25740	COG2271	Major facilitator Superfamily
EXW26_RS25755	COG3850	Histidine kinase
EXW26_RS25755	COG5002	protein histidine kinase activity
EXW26_RS25760	COG0745	RESPONSE REGULATOR receiver
EXW26_RS25765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW26_RS25780	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW26_RS25795	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW26_RS25855	COG1215	transferase activity, transferring glycosyl groups
EXW26_RS25855	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_RS25875	COG2244	polysaccharide biosynthetic process
EXW26_RS25880	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW26_RS25885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW26_RS25890	COG4464	protein tyrosine phosphatase activity
EXW26_RS25895	COG0489	protein tyrosine kinase activity
EXW26_RS25900	COG3944	biosynthesis protein
EXW26_RS25905	COG0489	protein tyrosine kinase activity
EXW26_RS25920	COG1609	Transcriptional regulator
EXW26_RS25930	COG0739	heme binding
EXW26_RS25945	COG3279	Response regulator of the LytR AlgR family
EXW26_RS25950	COG2385	sporulation resulting in formation of a cellular spore
EXW26_RS25965	COG4836	Membrane
EXW26_RS25970	COG1007	ATP synthesis coupled electron transport
EXW26_RS25975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_RS25980	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW26_RS25985	COG0713	ATP synthesis coupled electron transport
EXW26_RS25990	COG0839	Belongs to the complex I subunit 6 family
EXW26_RS26000	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW26_RS26005	COG0649	NAD binding
EXW26_RS26010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_RS26015	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_RS26020	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW26_RS26025	COG3300	MHYT domain
EXW26_RS26025	COG5001	Diguanylate cyclase
EXW26_RS26040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW26_RS26045	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW26_RS26050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW26_RS26055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW26_RS26060	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW26_RS26065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW26_RS26075	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW26_RS26100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW26_RS26110	COG0698	ribose 5-phosphate isomerase
EXW26_RS26120	COG2190	(PTS) system
EXW26_RS26125	COG2259	Doxx family
EXW26_RS26130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW26_RS26140	COG1971	Probably functions as a manganese efflux pump
EXW26_RS26145	COG0009	L-threonylcarbamoyladenylate synthase
EXW26_RS26160	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW26_RS26165	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW26_RS26170	COG1435	thymidine kinase activity
EXW26_RS26180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW26_RS26185	COG1494	fructose-1,6-bisphosphatase
EXW26_RS26205	COG4821	SIS domain
EXW26_RS26210	COG0504	CTP synthase activity
EXW26_RS26215	COG3343	RNA polymerase activity
EXW26_RS26225	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS26230	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS26235	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW26_RS26240	COG0183	Belongs to the thiolase family
EXW26_RS26245	COG0247	lactate metabolic process
EXW26_RS26245	COG2181	nitrate reductase activity
EXW26_RS26250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW26_RS26255	COG4294	response to UV
EXW26_RS26260	COG5001	Diguanylate cyclase
EXW26_RS26260	COG3300	MHYT domain
EXW26_RS26280	COG2197	response regulator
EXW26_RS26285	COG4585	Histidine kinase
EXW26_RS26290	COG0842	Transport permease protein
EXW26_RS26295	COG1131	(ABC) transporter
EXW26_RS26300	COG0024	Methionine aminopeptidase
EXW26_RS26310	COG2234	aminopeptidase activity
EXW26_RS26325	COG4506	Protein conserved in bacteria
EXW26_RS26330	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW26_RS26345	COG0010	Belongs to the arginase family
EXW26_RS26350	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW26_RS26355	COG2814	Major facilitator Superfamily
EXW26_RS26360	COG0789	Transcriptional regulator
EXW26_RS26365	COG0584	glycerophosphoryl diester phosphodiesterase
EXW26_RS26370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS26380	COG1994	Peptidase M50
EXW26_RS26390	COG1078	dGTPase activity
EXW26_RS26395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW26_RS26400	COG1120	ATPase activity
EXW26_RS26405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS26410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW26_RS26415	COG4844	belongs to the
EXW26_RS26435	COG0280	phosphate acetyltransferase
EXW26_RS26440	COG3253	May function as heme-dependent peroxidase
EXW26_RS26450	COG3773	Cell wall hydrolase
EXW26_RS26460	COG2363	Small membrane protein
EXW26_RS26475	COG2233	PERMEase
EXW26_RS26480	COG0561	phosphatase activity
EXW26_RS26485	COG2814	Major facilitator Superfamily
EXW26_RS26490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW26_RS26495	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW26_RS26500	COG1131	(ABC) transporter
EXW26_RS26505	COG2755	lipolytic protein G-D-S-L family
EXW26_RS26510	COG1609	Transcriptional regulator
EXW26_RS26520	COG0460	homoserine dehydrogenase
EXW26_RS26525	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW26_RS26530	COG2873	o-acetylhomoserine
EXW26_RS26545	COG2197	response regulator
EXW26_RS26550	COG4585	Histidine kinase
EXW26_RS26550	COG2203	Gaf domain
EXW26_RS26555	COG0351	phosphomethylpyrimidine kinase
EXW26_RS26560	COG3706	GGDEF domain
EXW26_RS26565	COG2879	small protein
EXW26_RS26570	COG1966	Carbon starvation protein
EXW26_RS26575	COG3279	Response regulator of the LytR AlgR family
EXW26_RS26580	COG0477	Major facilitator Superfamily
EXW26_RS26605	COG0840	transmembrane signaling receptor activity
EXW26_RS26615	COG1607	acyl-coa hydrolase
EXW26_RS26625	COG1216	Glycosyl transferase, family 2
EXW26_RS26630	COG0488	(ABC) transporter
EXW26_RS26645	COG0463	Glycosyl transferase, family 2
EXW26_RS26650	COG1309	transcriptional regulator
EXW26_RS26655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW26_RS26660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_RS26660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW26_RS26665	COG0628	permease
EXW26_RS26675	COG1380	Effector of murein hydrolase LrgA
EXW26_RS26680	COG3279	Response regulator of the LytR AlgR family
EXW26_RS26685	COG3275	phosphorelay sensor kinase activity
EXW26_RS26690	COG2814	Major facilitator Superfamily
EXW26_RS26695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW26_RS26700	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW26_RS26705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW26_RS26755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW26_RS26760	COG1272	protein, Hemolysin III
EXW26_RS26790	COG1164	Oligoendopeptidase f
EXW26_RS26800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW26_RS26810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW26_RS26815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW26_RS26820	COG4853	Protein conserved in bacteria
EXW26_RS26830	COG5002	protein histidine kinase activity
EXW26_RS26835	COG0745	RESPONSE REGULATOR receiver
EXW26_RS26865	COG0305	Participates in initiation and elongation during chromosome replication
EXW26_RS26870	COG0359	binds to the 23S rRNA
EXW26_RS26875	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW26_RS26880	COG4241	membrane
EXW26_RS26890	COG0629	single-stranded DNA binding
EXW26_RS26895	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW26_RS26900	COG0012	GTP binding
EXW26_RS26905	COG4481	Protein conserved in bacteria
EXW26_RS26910	COG0668	transmembrane transport
EXW26_RS26920	COG1475	DNA binding
EXW26_RS26925	COG1192	Involved in chromosome partitioning
EXW26_RS26930	COG1475	DNA binding
EXW26_RS26935	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW26_RS26940	COG0445	tRNA wobble uridine modification
EXW26_RS26945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW26_RS26950	COG1847	R3H domain protein
EXW26_RS26955	COG0706	membrane insertase activity
EXW26_RS26960	COG0594	ribonuclease P activity
EXW26_RS26965	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW26_RS26970	COG1192	Involved in chromosome partitioning
EXW26_RS26990	COG0577	efflux transmembrane transporter activity
EXW26_RS26995	COG1136	(ABC) transporter
EXW26_RS27010	COG3402	PFAM membrane-flanked domain
EXW26_RS27095	COG1923	regulation of RNA biosynthetic process
EXW26_RS27110	COG2188	Transcriptional regulator
EXW26_RS27125	COG1674	ftsk spoiiie
EXW26_RS27185	COG5002	protein histidine kinase activity
EXW26_RS27225	COG0384	phenazine biosynthesis protein PhzF
EXW26_RS27235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EXW26_RS27255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW26_RS27270	COG1674	ftsk spoiiie
EXW26_RS27385	COG0367	asparagine synthase
EXW26_RS27425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW26_RS27475	COG1396	sequence-specific DNA binding
EXW26_RS27500	COG0667	Aldo Keto reductase
EXW26_RS27530	COG0463	Glycosyl transferase, family 2
EXW26_RS27535	COG0463	Glycosyl transferase, family 2
EXW26_RS27540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW26_RS27545	COG1086	Polysaccharide biosynthesis protein
EXW26_RS27550	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW26_RS27555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_RS27560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW26_RS27575	COG2089	acid synthase
EXW26_RS27580	COG4641	Protein conserved in bacteria
EXW26_RS27645	COG3344	reverse transcriptase
EXW26_RS27655	COG0745	RESPONSE REGULATOR receiver
EXW26_RS27660	COG2205	protein histidine kinase activity
EXW26_RS27670	COG1136	(ABC) transporter
EXW26_RS27675	COG0577	efflux transmembrane transporter activity
EXW26_RS27685	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW26_RS27685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW26_RS27700	COG1136	(ABC) transporter
EXW26_RS27750	COG1115	amino acid carrier protein
EXW26_RS27755	COG1114	Component of the transport system for branched-chain amino acids
EXW26_RS27760	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW26_RS27760	COG3409	Peptidoglycan-binding domain 1 protein
EXW26_RS27765	COG2239	Acts as a magnesium transporter
EXW26_RS27775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW26_RS27790	COG0697	spore germination
EXW26_RS27805	COG1252	NADH dehydrogenase
EXW26_RS27810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS27810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW26_RS27815	COG2002	toxin-antitoxin pair type II binding
EXW26_RS27875	COG2814	Major facilitator Superfamily
EXW26_RS27900	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW26_RS27910	COG2002	toxin-antitoxin pair type II binding
EXW26_RS27950	COG0582	viral genome integration into host DNA
EXW26_RS27980	COG1696	Membrane protein involved in D-alanine export
EXW26_RS27990	COG2814	Major facilitator Superfamily
EXW26_RS28035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW26_RS28060	COG0791	NLP P60 protein
EXW26_RS28060	COG1388	LysM domain
EXW26_RS28060	COG3103	Sh3 type 3 domain protein
EXW26_RS28075	COG4974	Belongs to the 'phage' integrase family
EXW26_RS28105	COG0083	homoserine kinase activity
EXW26_RS28140	COG0840	transmembrane signaling receptor activity
EXW26_RS28165	COG2267	carboxylic ester hydrolase activity
EXW26_RS28170	COG1285	pathogenesis
EXW26_RS28175	COG0833	amino acid
EXW26_RS28200	COG0745	RESPONSE REGULATOR receiver
EXW26_RS28215	COG5002	protein histidine kinase activity
EXW26_RS28220	COG0745	RESPONSE REGULATOR receiver
EXW26_RS28225	COG4990	cell redox homeostasis
EXW26_RS28235	COG0768	penicillin binding
EXW26_RS28295	COG2423	ornithine cyclodeaminase activity
EXW26_RS28305	COG2175	clavaminate synthase activity
EXW26_RS28310	COG0137	argininosuccinate synthase activity
EXW26_RS28325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW26_RS28330	COG0251	oxidation-reduction process
EXW26_RS28340	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW26_RS28345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW26_RS28350	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS28375	COG0556	nucleotide-excision repair
EXW26_RS28380	COG0039	L-malate dehydrogenase activity
EXW26_RS28400	COG0436	Aminotransferase
EXW26_RS28440	COG0492	ferredoxin-NADP+ reductase activity
EXW26_RS28455	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW26_RS28455	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EXW26_RS28465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW26_RS28470	COG1960	acyl-CoA dehydrogenase activity
EXW26_RS28485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW26_RS28495	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW26_RS28525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW26_RS28535	COG0438	transferase activity, transferring glycosyl groups
EXW26_RS28540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW26_RS28545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW26_RS28560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW26_RS28570	COG1131	(ABC) transporter
EXW26_RS28585	COG2378	regulation of single-species biofilm formation
EXW26_RS28625	COG2002	toxin-antitoxin pair type II binding
EXW26_RS28685	COG2814	Major facilitator Superfamily
EXW26_RS28690	COG0583	DNA-binding transcription factor activity
EXW26_RS28770	COG2357	RelA SpoT domain protein
EXW26_RS28775	COG2814	Major facilitator Superfamily
EXW26_RS28785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW26_RS28855	COG3344	reverse transcriptase
EXW26_RS28885	COG1725	Transcriptional regulator
EXW26_RS28890	COG1131	(ABC) transporter
EXW26_RS28925	COG1329	Transcriptional regulator
EXW26_RS28945	COG3344	reverse transcriptase
EXW26_RS28980	COG4176	ABC-type proline glycine betaine transport system permease component
EXW26_RS28985	COG4175	Glycine betaine
EXW26_RS28985	COG0517	IMP dehydrogenase activity
EXW26_RS29050	COG0156	8-amino-7-oxononanoate synthase activity
EXW26_RS29060	COG4974	Belongs to the 'phage' integrase family
EXW26_RS29070	COG1132	(ABC) transporter
EXW26_RS29080	COG2814	Major facilitator Superfamily
EXW26_RS29105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW26_RS29115	COG0582	viral genome integration into host DNA
EXW26_RS29240	COG3883	PFAM NLP P60 protein
EXW26_RS29240	COG0791	NLP P60 protein
EXW26_RS29340	COG1396	sequence-specific DNA binding
EXW26_RS29370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW26_RS29375	COG4974	Belongs to the 'phage' integrase family
EXW26_RS29380	COG0024	Methionine aminopeptidase
EXW26_RS29415	COG2814	Major facilitator Superfamily
EXW26_RS29635	COG2076	Multidrug Resistance protein