locus-tag	class	description
EXW32_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW32_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW32_RS00015	COG2501	S4 domain
EXW32_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW32_RS00025	COG0187	DNA topoisomerase II activity
EXW32_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW32_RS00065	COG0516	GMP reductase activity
EXW32_RS00065	COG0517	IMP dehydrogenase activity
EXW32_RS00070	COG1686	Belongs to the peptidase S11 family
EXW32_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW32_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW32_RS00100	COG1428	Deoxynucleoside kinase
EXW32_RS00105	COG1428	Deoxynucleoside kinase
EXW32_RS00110	COG1335	isochorismatase
EXW32_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW32_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW32_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW32_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW32_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW32_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW32_RS00190	COG0470	DNA polymerase III
EXW32_RS00195	COG1774	PSP1 C-terminal conserved region
EXW32_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW32_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW32_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW32_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW32_RS00230	COG0084	hydrolase, TatD family'
EXW32_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW32_RS00250	COG4466	Protein conserved in bacteria
EXW32_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW32_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW32_RS00270	COG0251	oxidation-reduction process
EXW32_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW32_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW32_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW32_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW32_RS00310	COG2244	polysaccharide biosynthetic process
EXW32_RS00315	COG3956	TIGRFAM MazG family protein
EXW32_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW32_RS00340	COG1098	S1 RNA binding domain
EXW32_RS00355	COG2208	phosphoserine phosphatase activity
EXW32_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW32_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW32_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW32_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW32_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW32_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW32_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW32_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW32_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW32_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW32_RS00420	COG1396	sequence-specific DNA binding
EXW32_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW32_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW32_RS00515	COG3880	PFAM UvrB UvrC protein
EXW32_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW32_RS00525	COG0542	response to heat
EXW32_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW32_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW32_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW32_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW32_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW32_RS00560	COG1045	serine acetyltransferase
EXW32_RS00565	COG0215	cysteine-tRNA ligase activity
EXW32_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW32_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW32_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW32_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW32_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW32_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW32_RS00610	COG0081	regulation of translation
EXW32_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW32_RS00620	COG0222	ribosome binding
EXW32_RS00625	COG2813	Specifically methylates the guanine in position
EXW32_RS00630	COG0085	RNA polymerase activity
EXW32_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW32_RS00640	COG1358	cellular component organization or biogenesis
EXW32_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW32_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW32_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW32_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW32_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW32_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW32_RS00680	COG0089	rRNA binding
EXW32_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW32_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW32_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW32_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW32_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW32_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW32_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW32_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW32_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW32_RS00760	COG1841	ribosomal large subunit assembly
EXW32_RS00765	COG0200	Binds to the 23S rRNA
EXW32_RS00770	COG0201	protein transport
EXW32_RS00775	COG0563	adenylate kinase activity
EXW32_RS00780	COG0024	Methionine aminopeptidase
EXW32_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW32_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW32_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW32_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW32_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW32_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW32_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS00855	COG0489	protein tyrosine kinase activity
EXW32_RS00865	COG2194	sulfuric ester hydrolase activity
EXW32_RS00870	COG0726	polysaccharide deacetylase
EXW32_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW32_RS00955	COG4856	YbbR-like protein
EXW32_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW32_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS00990	COG2011	ABC-type metal ion transport system permease component
EXW32_RS01000	COG1464	Belongs to the NlpA lipoprotein family
EXW32_RS01005	COG0604	alcohol dehydrogenase
EXW32_RS01015	COG0277	FAD linked oxidase domain protein
EXW32_RS01020	COG2271	Major facilitator Superfamily
EXW32_RS01030	COG2814	Major facilitator Superfamily
EXW32_RS01045	COG0601	transmembrane transport
EXW32_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW32_RS01055	COG0444	Belongs to the ABC transporter superfamily
EXW32_RS01060	COG4608	Belongs to the ABC transporter superfamily
EXW32_RS01065	COG4166	transmembrane transport
EXW32_RS01075	COG2207	Transcriptional regulator
EXW32_RS01090	COG4166	transmembrane transport
EXW32_RS01095	COG4166	transmembrane transport
EXW32_RS01100	COG0656	L-ascorbic acid biosynthetic process
EXW32_RS01120	COG4149	molybdate abc transporter
EXW32_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW32_RS01130	COG1910	domain protein
EXW32_RS01145	COG0697	spore germination
EXW32_RS01160	COG0204	Acyl-transferase
EXW32_RS01170	COG1609	Transcriptional regulator
EXW32_RS01180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS01195	COG5298	Protein conserved in bacteria
EXW32_RS01215	COG0488	(ABC) transporter
EXW32_RS01220	COG4585	Histidine kinase
EXW32_RS01225	COG2197	response regulator
EXW32_RS01230	COG1131	(ABC) transporter
EXW32_RS01235	COG0842	Transport permease protein
EXW32_RS01235	COG1511	domain protein
EXW32_RS01240	COG0842	Transport permease protein
EXW32_RS01250	COG0747	negative chemotaxis
EXW32_RS01260	COG0601	transmembrane transport
EXW32_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW32_RS01270	COG0444	Belongs to the ABC transporter superfamily
EXW32_RS01275	COG4608	Belongs to the ABC transporter superfamily
EXW32_RS01280	COG0561	phosphatase activity
EXW32_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW32_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW32_RS01325	COG0531	amino acid
EXW32_RS01330	COG2814	Major facilitator Superfamily
EXW32_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW32_RS01350	COG4294	response to UV
EXW32_RS01355	COG0705	Rhomboid family
EXW32_RS01360	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW32_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW32_RS01375	COG0864	Transcriptional regulator
EXW32_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW32_RS01385	COG2183	response to ionizing radiation
EXW32_RS01485	COG0802	atpase or kinase
EXW32_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW32_RS01495	COG0456	acetyltransferase
EXW32_RS01505	COG0488	(ABC) transporter
EXW32_RS01510	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW32_RS01520	COG1266	CAAX protease self-immunity
EXW32_RS01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW32_RS01530	COG0459	protein refolding
EXW32_RS01535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW32_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
EXW32_RS01540	COG2252	PERMEase
EXW32_RS01550	COG5002	protein histidine kinase activity
EXW32_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW32_RS01630	COG2205	protein histidine kinase activity
EXW32_RS01635	COG0745	RESPONSE REGULATOR receiver
EXW32_RS01655	COG0697	spore germination
EXW32_RS01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW32_RS01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW32_RS01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW32_RS01695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW32_RS01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW32_RS01705	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW32_RS01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW32_RS01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW32_RS01720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW32_RS01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW32_RS01730	COG0138	bifunctional purine biosynthesis protein purh
EXW32_RS01735	COG0151	Belongs to the GarS family
EXW32_RS01755	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW32_RS01760	COG0210	DNA helicase
EXW32_RS01765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW32_RS01770	COG4851	CamS sex pheromone cAM373 precursor
EXW32_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS01785	COG1335	isochorismatase
EXW32_RS01795	COG2011	ABC-type metal ion transport system permease component
EXW32_RS01800	COG1464	Belongs to the NlpA lipoprotein family
EXW32_RS01815	COG0003	Pfam Anion-transporting ATPase
EXW32_RS01820	COG1846	Transcriptional regulator
EXW32_RS01825	COG4682	membrane
EXW32_RS01835	COG0154	amidase activity
EXW32_RS01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW32_RS01845	COG1597	lipid kinase activity
EXW32_RS01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS01870	COG2076	Multidrug Resistance protein
EXW32_RS01875	COG2309	aminopeptidase activity
EXW32_RS01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW32_RS01905	COG5002	protein histidine kinase activity
EXW32_RS01910	COG4807	Protein conserved in bacteria
EXW32_RS01935	COG1757	Na H antiporter
EXW32_RS01940	COG1473	amidohydrolase
EXW32_RS01955	COG0450	alkyl hydroperoxide reductase
EXW32_RS01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW32_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS01990	COG0492	ferredoxin-NADP+ reductase activity
EXW32_RS02000	COG0166	Belongs to the GPI family
EXW32_RS02025	COG5002	protein histidine kinase activity
EXW32_RS02045	COG3541	Predicted nucleotidyltransferase
EXW32_RS02050	COG2814	Major facilitator Superfamily
EXW32_RS02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW32_RS02055	COG0723	plastoquinol--plastocyanin reductase activity
EXW32_RS02065	COG0765	amino acid transport
EXW32_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW32_RS02080	COG0840	transmembrane signaling receptor activity
EXW32_RS02080	COG3290	protein histidine kinase activity
EXW32_RS02105	COG0549	Belongs to the carbamate kinase family
EXW32_RS02120	COG0277	FAD linked oxidase domain protein
EXW32_RS02125	COG0366	Alpha amylase catalytic
EXW32_RS02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS02130	COG2190	(PTS) system
EXW32_RS02130	COG1263	PTS System
EXW32_RS02220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW32_RS02225	COG0352	thiamine-phosphate diphosphorylase activity
EXW32_RS02230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW32_RS02245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW32_RS02250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW32_RS02255	COG1116	anion transmembrane transporter activity
EXW32_RS02260	COG0488	(ABC) transporter
EXW32_RS02305	COG2270	Major facilitator Superfamily
EXW32_RS02335	COG2310	stress, protein
EXW32_RS02340	COG2310	stress, protein
EXW32_RS02345	COG2310	stress, protein
EXW32_RS02350	COG0861	Integral membrane protein TerC family
EXW32_RS02360	COG3853	Toxic anion resistance protein (TelA)
EXW32_RS02370	COG4840	Belongs to the UPF0435 family
EXW32_RS02375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW32_RS02385	COG1295	ribonuclease BN
EXW32_RS02390	COG2217	Heavy metal translocating P-type atpase
EXW32_RS02395	COG0697	spore germination
EXW32_RS02415	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS02430	COG3871	stress protein (general stress protein 26)
EXW32_RS02435	COG0387	Pfam Sodium calcium exchanger
EXW32_RS02445	COG0535	radical SAM domain protein
EXW32_RS02465	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW32_RS02485	COG3829	transcription factor binding
EXW32_RS02495	COG0833	amino acid
EXW32_RS02500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW32_RS02520	COG2066	Belongs to the glutaminase family
EXW32_RS02525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS02525	COG1263	PTS System
EXW32_RS02530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS02545	COG1216	Glycosyl transferase, family 2
EXW32_RS02555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW32_RS02555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW32_RS02560	COG0463	Glycosyl transferase, family 2
EXW32_RS02575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW32_RS02580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW32_RS02595	COG1228	amidohydrolase
EXW32_RS02600	COG1090	epimerase
EXW32_RS02605	COG2137	regulation of response to DNA damage stimulus
EXW32_RS02630	COG1988	membrane-bound metal-dependent
EXW32_RS02635	COG1194	a g-specific adenine glycosylase
EXW32_RS02655	COG3557	Belongs to the UPF0374 family
EXW32_RS02660	COG1132	(ABC) transporter
EXW32_RS02665	COG4129	membrane
EXW32_RS02670	COG0070	glutamate synthase
EXW32_RS02670	COG0069	glutamate synthase activity
EXW32_RS02670	COG0067	glutamate synthase
EXW32_RS02675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW32_RS02680	COG4555	ABC transporter
EXW32_RS02700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW32_RS02705	COG0735	belongs to the Fur family
EXW32_RS02825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW32_RS02830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW32_RS02850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW32_RS02860	COG2766	serine protein kinase
EXW32_RS02865	COG2718	Belongs to the UPF0229 family
EXW32_RS02880	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW32_RS02885	COG2268	Band 7 protein
EXW32_RS02895	COG3290	protein histidine kinase activity
EXW32_RS02900	COG4565	transcriptional regulatory protein
EXW32_RS02905	COG2851	Citrate transporter
EXW32_RS02930	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW32_RS02935	COG3842	ATPase activity
EXW32_RS02940	COG1175	transmembrane transport
EXW32_RS02945	COG0395	ABC-type sugar transport system, permease component
EXW32_RS02955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW32_RS02960	COG0745	RESPONSE REGULATOR receiver
EXW32_RS02965	COG5002	protein histidine kinase activity
EXW32_RS02975	COG4990	cell redox homeostasis
EXW32_RS02985	COG3290	protein histidine kinase activity
EXW32_RS02990	COG4565	transcriptional regulatory protein
EXW32_RS02995	COG3493	citrate carrier protein
EXW32_RS03000	COG0281	malic enzyme
EXW32_RS03010	COG0697	spore germination
EXW32_RS03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS03025	COG5002	protein histidine kinase activity
EXW32_RS03030	COG0745	RESPONSE REGULATOR receiver
EXW32_RS03035	COG0456	acetyltransferase
EXW32_RS03040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW32_RS03045	COG3383	formate dehydrogenase (NAD+) activity
EXW32_RS03050	COG2427	Protein of unknown function (DUF1641)
EXW32_RS03065	COG0531	amino acid
EXW32_RS03075	COG0640	Transcriptional regulator
EXW32_RS03080	COG2217	Heavy metal translocating P-type atpase
EXW32_RS03085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW32_RS03100	COG3227	Zinc metalloprotease (Elastase)
EXW32_RS03120	COG2720	vancomycin resistance protein
EXW32_RS03125	COG1316	TRANSCRIPTIONal
EXW32_RS03130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS03135	COG0346	lactoylglutathione lyase activity
EXW32_RS03140	COG1253	flavin adenine dinucleotide binding
EXW32_RS03145	COG1027	Aspartate ammonia-lyase
EXW32_RS03150	COG1620	l-lactate permease
EXW32_RS03155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS03170	COG3104	oligopeptide transport
EXW32_RS03175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS03180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS03185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS03200	COG0156	8-amino-7-oxononanoate synthase activity
EXW32_RS03205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW32_RS03215	COG4548	von Willebrand factor, type A
EXW32_RS03220	COG0714	Associated with various cellular activities
EXW32_RS03240	COG0531	amino acid
EXW32_RS03245	COG2188	Transcriptional regulator
EXW32_RS03250	COG1263	PTS System
EXW32_RS03250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS03255	COG0366	Alpha amylase catalytic
EXW32_RS03270	COG0697	spore germination
EXW32_RS03275	COG4585	Histidine kinase
EXW32_RS03280	COG2197	response regulator
EXW32_RS03285	COG1404	Belongs to the peptidase S8 family
EXW32_RS03300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW32_RS03305	COG1115	amino acid carrier protein
EXW32_RS03310	COG1126	abc transporter atp-binding protein
EXW32_RS03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW32_RS03320	COG0765	amino acid transport
EXW32_RS03325	COG0765	amino acid transport
EXW32_RS03330	COG0833	amino acid
EXW32_RS03340	COG2378	regulation of single-species biofilm formation
EXW32_RS03345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW32_RS03350	COG5002	protein histidine kinase activity
EXW32_RS03365	COG0659	secondary active sulfate transmembrane transporter activity
EXW32_RS03380	COG2271	Major facilitator Superfamily
EXW32_RS03385	COG1846	Transcriptional regulator
EXW32_RS03390	COG0477	Major facilitator Superfamily
EXW32_RS03395	COG1609	Transcriptional regulator
EXW32_RS03400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW32_RS03405	COG1869	D-ribose catabolic process
EXW32_RS03415	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW32_RS03420	COG1879	ABC-type sugar transport system periplasmic component
EXW32_RS03450	COG1063	alcohol dehydrogenase
EXW32_RS03465	COG3568	Endonuclease Exonuclease Phosphatase
EXW32_RS03495	COG0840	transmembrane signaling receptor activity
EXW32_RS03500	COG3584	3D domain protein
EXW32_RS03500	COG1388	LysM domain
EXW32_RS03505	COG1476	TRANSCRIPTIONal
EXW32_RS03525	COG3104	oligopeptide transport
EXW32_RS03530	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS03545	COG1113	amino acid transport
EXW32_RS03550	COG2252	PERMEase
EXW32_RS03565	COG2153	protein acetylation
EXW32_RS03575	COG0475	glutathione-regulated potassium exporter activity
EXW32_RS03575	COG0569	domain protein
EXW32_RS03585	COG1845	cytochrome c oxidase, subunit III
EXW32_RS03590	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW32_RS03600	COG0833	amino acid
EXW32_RS03605	COG4990	cell redox homeostasis
EXW32_RS03620	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW32_RS03625	COG0697	spore germination
EXW32_RS03630	COG0531	amino acid
EXW32_RS03640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW32_RS03645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW32_RS03655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW32_RS03660	COG0573	inorganic phosphate transmembrane transporter activity
EXW32_RS03665	COG0581	inorganic phosphate transmembrane transporter activity
EXW32_RS03675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW32_RS03795	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW32_RS03810	COG4991	sh3 domain protein
EXW32_RS03810	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS03810	COG3103	Sh3 type 3 domain protein
EXW32_RS03815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW32_RS03820	COG1116	anion transmembrane transporter activity
EXW32_RS03825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW32_RS03830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW32_RS03835	COG0352	thiamine-phosphate diphosphorylase activity
EXW32_RS03840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW32_RS03845	COG2104	thiamine diphosphate biosynthetic process
EXW32_RS03850	COG2022	thiamine diphosphate biosynthetic process
EXW32_RS03855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW32_RS03860	COG0351	phosphomethylpyrimidine kinase
EXW32_RS03885	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW32_RS03890	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW32_RS03895	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW32_RS03900	COG2205	protein histidine kinase activity
EXW32_RS03905	COG2814	Major facilitator Superfamily
EXW32_RS03910	COG1846	Transcriptional regulator
EXW32_RS03930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW32_RS03935	COG1129	ABC transporter
EXW32_RS03940	COG1879	ABC-type sugar transport system periplasmic component
EXW32_RS03945	COG2252	PERMEase
EXW32_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS03965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW32_RS03970	COG1621	beta-fructofuranosidase activity
EXW32_RS03975	COG1263	PTS System
EXW32_RS03975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS03980	COG1609	Transcriptional regulator
EXW32_RS04030	COG0778	Nitroreductase
EXW32_RS04035	COG2719	SpoVR family
EXW32_RS04060	COG1937	Protein conserved in bacteria
EXW32_RS04065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS04065	COG0425	Belongs to the sulfur carrier protein TusA family
EXW32_RS04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS04075	COG0425	Belongs to the sulfur carrier protein TusA family
EXW32_RS04080	COG0425	Belongs to the sulfur carrier protein TusA family
EXW32_RS04080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS04085	COG2210	Belongs to the sulfur carrier protein TusA family
EXW32_RS04090	COG0730	response to heat
EXW32_RS04100	COG1316	TRANSCRIPTIONal
EXW32_RS04105	COG0604	alcohol dehydrogenase
EXW32_RS04110	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW32_RS04115	COG0604	alcohol dehydrogenase
EXW32_RS04120	COG2814	Major facilitator Superfamily
EXW32_RS04130	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW32_RS04130	COG3711	transcriptional antiterminator
EXW32_RS04135	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW32_RS04140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW32_RS04165	COG3584	3D domain protein
EXW32_RS04165	COG1388	LysM domain
EXW32_RS04170	COG0577	efflux transmembrane transporter activity
EXW32_RS04175	COG1136	(ABC) transporter
EXW32_RS04185	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW32_RS04200	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS04205	COG3546	catalase activity
EXW32_RS04235	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS04265	COG0531	amino acid
EXW32_RS04270	COG0475	glutathione-regulated potassium exporter activity
EXW32_RS04280	COG1737	Transcriptional regulator
EXW32_RS04285	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW32_RS04290	COG1263	PTS System
EXW32_RS04290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS04300	COG2259	Doxx family
EXW32_RS04320	COG0697	spore germination
EXW32_RS04325	COG1522	sequence-specific DNA binding
EXW32_RS04335	COG0300	oxidoreductase activity
EXW32_RS04350	COG2076	Multidrug Resistance protein
EXW32_RS04355	COG1309	transcriptional regulator
EXW32_RS04360	COG2814	Major facilitator Superfamily
EXW32_RS04365	COG1733	regulation of RNA biosynthetic process
EXW32_RS04380	COG4533	DNA binding
EXW32_RS04385	COG2211	Major facilitator Superfamily
EXW32_RS04395	COG0693	protein deglycase activity
EXW32_RS04405	COG0531	amino acid
EXW32_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS04415	COG1132	(ABC) transporter
EXW32_RS04420	COG1132	(ABC) transporter
EXW32_RS04425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW32_RS04430	COG0765	amino acid transport
EXW32_RS04435	COG1126	abc transporter atp-binding protein
EXW32_RS04450	COG0189	ligase activity
EXW32_RS04460	COG4399	Belongs to the UPF0754 family
EXW32_RS04465	COG3679	Belongs to the UPF0342 family
EXW32_RS04480	COG0028	Belongs to the TPP enzyme family
EXW32_RS04485	COG3527	Alpha-acetolactate decarboxylase
EXW32_RS04490	COG0463	Glycosyl transferase, family 2
EXW32_RS04495	COG1216	Glycosyl transferase, family 2
EXW32_RS04500	COG2094	Belongs to the DNA glycosylase MPG family
EXW32_RS04505	COG0561	phosphatase activity
EXW32_RS04515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW32_RS04520	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS04530	COG0659	secondary active sulfate transmembrane transporter activity
EXW32_RS04545	COG0653	protein targeting
EXW32_RS04550	COG2244	polysaccharide biosynthetic process
EXW32_RS04560	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS04580	COG1696	Membrane protein involved in D-alanine export
EXW32_RS04595	COG1024	Enoyl-CoA hydratase
EXW32_RS04610	COG1363	Peptidase, m42
EXW32_RS04625	COG2318	DinB family
EXW32_RS04645	COG0579	oxidoreductase
EXW32_RS04680	COG0601	transmembrane transport
EXW32_RS04685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW32_RS04690	COG0444	Belongs to the ABC transporter superfamily
EXW32_RS04695	COG4608	Belongs to the ABC transporter superfamily
EXW32_RS04785	COG0477	Major facilitator Superfamily
EXW32_RS04790	COG3290	protein histidine kinase activity
EXW32_RS04795	COG4565	transcriptional regulatory protein
EXW32_RS04800	COG3181	Tripartite tricarboxylate transporter family receptor
EXW32_RS04840	COG0789	Transcriptional regulator
EXW32_RS04840	COG4978	Transcriptional regulator
EXW32_RS04855	COG0305	Participates in initiation and elongation during chromosome replication
EXW32_RS04885	COG0477	Major facilitator Superfamily
EXW32_RS04920	COG3711	transcriptional antiterminator
EXW32_RS04925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS04925	COG2190	(PTS) system
EXW32_RS04925	COG1263	PTS System
EXW32_RS04930	COG2723	6-phospho-beta-galactosidase activity
EXW32_RS04935	COG0456	acetyltransferase
EXW32_RS04945	COG1183	phosphatidylcholine synthase activity
EXW32_RS05000	COG2814	Major facilitator Superfamily
EXW32_RS05005	COG0640	Transcriptional regulator
EXW32_RS05025	COG2376	Dihydroxyacetone kinase
EXW32_RS05035	COG2376	Dihydroxyacetone kinase
EXW32_RS05050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW32_RS05065	COG1335	isochorismatase
EXW32_RS05090	COG0076	glutamate decarboxylase activity
EXW32_RS05110	COG4085	toxin activity
EXW32_RS05110	COG1525	nuclease
EXW32_RS05110	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS05120	COG0582	viral genome integration into host DNA
EXW32_RS05130	COG2378	regulation of single-species biofilm formation
EXW32_RS05135	COG2318	DinB family
EXW32_RS05140	COG4932	domain protein
EXW32_RS05140	COG3266	domain, Protein
EXW32_RS05140	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW32_RS05150	COG0825	malonyl-CoA metabolic process
EXW32_RS05170	COG3237	CsbD-like
EXW32_RS05190	COG2172	sigma factor antagonist activity
EXW32_RS05195	COG1191	sigma factor activity
EXW32_RS05205	COG2208	phosphoserine phosphatase activity
EXW32_RS05210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW32_RS05215	COG0784	Response regulator, receiver
EXW32_RS05215	COG2205	protein histidine kinase activity
EXW32_RS05215	COG5002	protein histidine kinase activity
EXW32_RS05250	COG2807	transmembrane transport
EXW32_RS05255	COG2186	Transcriptional regulator
EXW32_RS05260	COG4585	Histidine kinase
EXW32_RS05265	COG2197	response regulator
EXW32_RS05295	COG0420	3'-5' exonuclease activity
EXW32_RS05300	COG4717	serine-type aminopeptidase activity
EXW32_RS05305	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW32_RS05315	COG0346	lactoylglutathione lyase activity
EXW32_RS05320	COG0346	lactoylglutathione lyase activity
EXW32_RS05325	COG0457	Tetratricopeptide repeat
EXW32_RS05335	COG2267	carboxylic ester hydrolase activity
EXW32_RS05360	COG3620	sequence-specific DNA binding
EXW32_RS05365	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW32_RS05370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW32_RS05375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW32_RS05380	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW32_RS05385	COG1595	DNA-templated transcription, initiation
EXW32_RS05400	COG3973	AAA domain
EXW32_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW32_RS05420	COG1846	Transcriptional regulator
EXW32_RS05430	COG0537	adenosine 5'-monophosphoramidase activity
EXW32_RS05435	COG1131	(ABC) transporter
EXW32_RS05440	COG4473	ABC transporter
EXW32_RS05450	COG0247	lactate metabolic process
EXW32_RS05455	COG1139	Iron-sulfur cluster binding protein
EXW32_RS05460	COG1556	Lactate utilization protein
EXW32_RS05480	COG3402	PFAM membrane-flanked domain
EXW32_RS05485	COG3428	Bacterial PH domain
EXW32_RS05515	COG3402	PFAM membrane-flanked domain
EXW32_RS05520	COG3428	Bacterial PH domain
EXW32_RS05525	COG2329	Antibiotic biosynthesis monooxygenase
EXW32_RS05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW32_RS05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW32_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW32_RS05570	COG1309	transcriptional regulator
EXW32_RS05610	COG2378	regulation of single-species biofilm formation
EXW32_RS05615	COG1609	Transcriptional regulator
EXW32_RS05625	COG1234	tRNA 3'-trailer cleavage
EXW32_RS05630	COG0095	Lipoate-protein ligase
EXW32_RS05640	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS05655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW32_RS05660	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW32_RS05665	COG4208	sulfate ABC transporter
EXW32_RS05680	COG1408	metallophosphoesterase
EXW32_RS05685	COG1078	dGTPase activity
EXW32_RS05700	COG1595	DNA-templated transcription, initiation
EXW32_RS05705	COG2207	Transcriptional regulator
EXW32_RS05705	COG3708	Transcriptional regulator
EXW32_RS05710	COG2205	protein histidine kinase activity
EXW32_RS05715	COG0745	RESPONSE REGULATOR receiver
EXW32_RS05730	COG0501	Belongs to the peptidase M48B family
EXW32_RS05735	COG0697	spore germination
EXW32_RS05760	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW32_RS05765	COG2224	Isocitrate lyase
EXW32_RS05775	COG1278	Cold shock
EXW32_RS05785	COG4903	ComK protein
EXW32_RS05790	COG0398	Pfam SNARE associated Golgi protein
EXW32_RS05800	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW32_RS05805	COG1074	ATP-dependent DNA helicase activity
EXW32_RS05855	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW32_RS05880	COG0367	asparagine synthase
EXW32_RS05890	COG0753	catalase activity
EXW32_RS05895	COG0004	ammonium transporteR
EXW32_RS05905	COG1666	GTP binding
EXW32_RS05910	COG2996	Protein conserved in bacteria
EXW32_RS05915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW32_RS05925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS05940	COG0561	phosphatase activity
EXW32_RS05960	COG2267	carboxylic ester hydrolase activity
EXW32_RS05975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW32_RS05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW32_RS05985	COG5504	Zn-dependent protease
EXW32_RS05995	COG0180	Tryptophanyl-tRNA synthetase
EXW32_RS06005	COG4166	transmembrane transport
EXW32_RS06010	COG0601	transmembrane transport
EXW32_RS06015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW32_RS06020	COG0444	Belongs to the ABC transporter superfamily
EXW32_RS06025	COG4608	Belongs to the ABC transporter superfamily
EXW32_RS06030	COG0534	Mate efflux family protein
EXW32_RS06035	COG4166	transmembrane transport
EXW32_RS06050	COG0861	Integral membrane protein TerC family
EXW32_RS06055	COG4862	establishment of competence for transformation
EXW32_RS06060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW32_RS06070	COG1164	Oligoendopeptidase f
EXW32_RS06085	COG2346	COG2346, Truncated hemoglobins
EXW32_RS06090	COG4116	CYTH
EXW32_RS06100	COG2357	RelA SpoT domain protein
EXW32_RS06110	COG0564	pseudouridine synthase activity
EXW32_RS06120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW32_RS06125	COG0772	Belongs to the SEDS family
EXW32_RS06130	COG1216	Glycosyl transferase, family 2
EXW32_RS06150	COG0457	Tetratricopeptide repeat
EXW32_RS06150	COG0463	Glycosyl transferase, family 2
EXW32_RS06170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW32_RS06185	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW32_RS06230	COG2153	protein acetylation
EXW32_RS06235	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW32_RS06240	COG2382	esterase
EXW32_RS06265	COG5492	domain, Protein
EXW32_RS06270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW32_RS06280	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW32_RS06280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW32_RS06285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW32_RS06290	COG0134	indole-3-glycerol-phosphate synthase activity
EXW32_RS06295	COG0135	phosphoribosylanthranilate isomerase activity
EXW32_RS06300	COG0133	tryptophan synthase activity
EXW32_RS06305	COG0159	tryptophan synthase activity
EXW32_RS06315	COG1620	l-lactate permease
EXW32_RS06320	COG5634	Uncharacterized conserved protein (DUF2278)
EXW32_RS06355	COG2226	methyltransferase
EXW32_RS06375	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW32_RS06380	COG0567	Dehydrogenase, E1 component
EXW32_RS06385	COG1476	TRANSCRIPTIONal
EXW32_RS06440	COG1686	Belongs to the peptidase S11 family
EXW32_RS06445	COG0681	Belongs to the peptidase S26 family
EXW32_RS06480	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS06490	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW32_RS06495	COG1177	transmembrane transport
EXW32_RS06500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW32_RS06510	COG2409	Drug exporters of the RND superfamily
EXW32_RS06520	COG0564	pseudouridine synthase activity
EXW32_RS06530	COG2340	Cysteine-rich secretory protein family
EXW32_RS06535	COG0247	lactate metabolic process
EXW32_RS06540	COG0277	FAD linked oxidase domain protein
EXW32_RS06545	COG3835	regulator
EXW32_RS06555	COG0745	RESPONSE REGULATOR receiver
EXW32_RS06560	COG5002	protein histidine kinase activity
EXW32_RS06565	COG2186	Transcriptional regulator
EXW32_RS06570	COG0247	lactate metabolic process
EXW32_RS06575	COG1139	Iron-sulfur cluster binding protein
EXW32_RS06580	COG1556	Lactate utilization protein
EXW32_RS06585	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW32_RS06595	COG2116	formate transmembrane transporter activity
EXW32_RS06600	COG0861	Integral membrane protein TerC family
EXW32_RS06605	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW32_RS06615	COG2030	dehydratase
EXW32_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS06640	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW32_RS06650	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW32_RS06665	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW32_RS06670	COG3842	ATPase activity
EXW32_RS06680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW32_RS06685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW32_RS06695	COG1349	DNA-binding transcription factor activity
EXW32_RS06705	COG0235	Class ii aldolase
EXW32_RS06715	COG2861	carbohydrate metabolic process
EXW32_RS06725	COG3852	Histidine kinase
EXW32_RS06730	COG1846	Transcriptional regulator
EXW32_RS06740	COG2318	DinB family
EXW32_RS06745	COG5002	protein histidine kinase activity
EXW32_RS06750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW32_RS06755	COG0720	synthase
EXW32_RS06765	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW32_RS06770	COG4873	Protein conserved in bacteria
EXW32_RS06785	COG0456	acetyltransferase
EXW32_RS06800	COG1780	Probably involved in ribonucleotide reductase function
EXW32_RS06815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW32_RS06820	COG0531	amino acid
EXW32_RS06825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW32_RS06840	COG2204	response regulator
EXW32_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS06855	COG1725	Transcriptional regulator
EXW32_RS06860	COG1131	(ABC) transporter
EXW32_RS06870	COG1131	(ABC) transporter
EXW32_RS06875	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW32_RS06880	COG1266	CAAX protease self-immunity
EXW32_RS06890	COG1522	sequence-specific DNA binding
EXW32_RS06900	COG1335	isochorismatase
EXW32_RS06910	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW32_RS06915	COG2070	2-Nitropropane dioxygenase
EXW32_RS06920	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW32_RS06925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW32_RS06930	COG1696	Membrane protein involved in D-alanine export
EXW32_RS06955	COG0716	FMN binding
EXW32_RS06990	COG0534	Mate efflux family protein
EXW32_RS06995	COG1968	undecaprenyl-diphosphatase activity
EXW32_RS07015	COG1846	Transcriptional regulator
EXW32_RS07030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW32_RS07040	COG3874	Sporulation protein YtfJ
EXW32_RS07060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS07065	COG0028	Belongs to the TPP enzyme family
EXW32_RS07070	COG0440	acetolactate synthase activity
EXW32_RS07080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW32_RS07090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW32_RS07100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW32_RS07105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW32_RS07115	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW32_RS07120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW32_RS07125	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW32_RS07130	COG0107	imidazoleglycerol-phosphate synthase activity
EXW32_RS07140	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW32_RS07145	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW32_RS07160	COG1183	phosphatidylcholine synthase activity
EXW32_RS07165	COG1368	sulfuric ester hydrolase activity
EXW32_RS07175	COG0019	diaminopimelate decarboxylase activity
EXW32_RS07185	COG0175	sulfate reduction
EXW32_RS07190	COG2046	Belongs to the sulfate adenylyltransferase family
EXW32_RS07195	COG0529	Catalyzes the synthesis of activated sulfate
EXW32_RS07200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW32_RS07220	COG1648	precorrin-2 dehydrogenase activity
EXW32_RS07225	COG0733	neurotransmitter:sodium symporter activity
EXW32_RS07250	COG1757	Na H antiporter
EXW32_RS07265	COG4758	membrane
EXW32_RS07270	COG4585	Histidine kinase
EXW32_RS07275	COG2197	response regulator
EXW32_RS07285	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS07295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW32_RS07335	COG0730	response to heat
EXW32_RS07340	COG0306	phosphate transporter
EXW32_RS07345	COG1392	Phosphate transport regulator
EXW32_RS07350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS07365	COG3852	Histidine kinase
EXW32_RS07370	COG1801	Protein of unknown function DUF72
EXW32_RS07380	COG0582	viral genome integration into host DNA
EXW32_RS07385	COG5002	protein histidine kinase activity
EXW32_RS07400	COG0392	lysyltransferase activity
EXW32_RS07400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW32_RS07415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW32_RS07420	COG1686	Belongs to the peptidase S11 family
EXW32_RS07425	COG2715	membrane protein required for spore maturation
EXW32_RS07430	COG0700	Nucleoside recognition
EXW32_RS07435	COG1187	pseudouridine synthase activity
EXW32_RS07445	COG1333	cytochrome c biogenesis protein
EXW32_RS07450	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW32_RS07455	COG0745	RESPONSE REGULATOR receiver
EXW32_RS07460	COG5002	protein histidine kinase activity
EXW32_RS07465	COG2096	Adenosyltransferase
EXW32_RS07470	COG4942	peptidase
EXW32_RS07480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW32_RS07485	COG1141	Ferredoxin
EXW32_RS07490	COG4955	Helix-turn-helix domain
EXW32_RS07495	COG0514	ATP-dependent DNA helicase (RecQ)
EXW32_RS07500	COG1266	CAAX protease self-immunity
EXW32_RS07510	COG1408	metallophosphoesterase
EXW32_RS07525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW32_RS07545	COG0492	ferredoxin-NADP+ reductase activity
EXW32_RS07550	COG0252	asparaginase activity
EXW32_RS07560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW32_RS07570	COG1304	FMN binding
EXW32_RS07600	COG1160	GTP binding
EXW32_RS07605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW32_RS07625	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW32_RS07635	COG0302	gtp cyclohydrolase
EXW32_RS07640	COG0142	geranyltranstransferase activity
EXW32_RS07645	COG2226	methyltransferase
EXW32_RS07650	COG0142	geranyltranstransferase activity
EXW32_RS07665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW32_RS07675	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW32_RS07680	COG0457	Tetratricopeptide repeat
EXW32_RS07685	COG5582	Belongs to the UPF0302 family
EXW32_RS07700	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW32_RS07715	COG4347	Protein of unknown function (DUF1405)
EXW32_RS07730	COG2738	Putative neutral zinc metallopeptidase
EXW32_RS07740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS07745	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW32_RS07750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW32_RS07755	COG1803	Methylglyoxal synthase
EXW32_RS07760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW32_RS07765	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS07770	COG0617	tRNA 3'-terminal CCA addition
EXW32_RS07780	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW32_RS07785	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW32_RS07795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW32_RS07795	COG1199	ATP-dependent helicase activity
EXW32_RS07815	COG3935	DnaD domain protein
EXW32_RS07820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW32_RS07830	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW32_RS07830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS07835	COG3331	DNA recombination
EXW32_RS07870	COG4474	Belongs to the UPF0398 family
EXW32_RS07875	COG3599	regulation of cell shape
EXW32_RS07885	COG0116	Belongs to the methyltransferase superfamily
EXW32_RS07895	COG1199	ATP-dependent helicase activity
EXW32_RS07900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW32_RS07910	COG0024	Methionine aminopeptidase
EXW32_RS07920	COG2233	PERMEase
EXW32_RS07925	COG2311	Membrane
EXW32_RS07930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW32_RS07940	COG0456	acetyltransferase
EXW32_RS07950	COG2897	thiosulfate sulfurtransferase activity
EXW32_RS07990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW32_RS08005	COG0454	-acetyltransferase
EXW32_RS08025	COG0328	RNA-DNA hybrid ribonuclease activity
EXW32_RS08060	COG3403	YqcI/YcgG family
EXW32_RS08065	COG1280	lysine exporter protein (LysE YggA)
EXW32_RS08080	COG3162	membrane
EXW32_RS08085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW32_RS08090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS08100	COG0475	glutathione-regulated potassium exporter activity
EXW32_RS08105	COG0789	Transcriptional regulator
EXW32_RS08105	COG4978	Transcriptional regulator
EXW32_RS08115	COG2323	membrane
EXW32_RS08120	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW32_RS08150	COG2814	Major facilitator Superfamily
EXW32_RS08170	COG1923	regulation of RNA biosynthetic process
EXW32_RS08180	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW32_RS08185	COG1360	Flagellar Motor Protein
EXW32_RS08190	COG2201	protein-glutamate methylesterase activity
EXW32_RS08195	COG2198	Histidine kinase
EXW32_RS08195	COG0643	Histidine kinase
EXW32_RS08200	COG1776	CheC inhibitor of MCP methylation
EXW32_RS08200	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW32_RS08215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW32_RS08235	COG1256	bacterial-type flagellum assembly
EXW32_RS08240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW32_RS08260	COG1815	bacterial-type flagellum-dependent cell motility
EXW32_RS08265	COG1558	bacterial-type flagellum-dependent cell motility
EXW32_RS08275	COG1766	The M ring may be actively involved in energy transduction
EXW32_RS08280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW32_RS08290	COG1157	protein secretion by the type III secretion system
EXW32_RS08310	COG1749	Flagellar hook protein flgE
EXW32_RS08325	COG0784	Response regulator, receiver
EXW32_RS08325	COG0835	chemotaxis
EXW32_RS08345	COG0861	Integral membrane protein TerC family
EXW32_RS08355	COG3383	formate dehydrogenase (NAD+) activity
EXW32_RS08360	COG2427	Protein of unknown function (DUF1641)
EXW32_RS08365	COG5609	conserved protein (DUF2294)
EXW32_RS08370	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW32_RS08380	COG2116	formate transmembrane transporter activity
EXW32_RS08385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW32_RS08390	COG0303	'Molybdopterin
EXW32_RS08395	COG0314	molybdopterin synthase activity
EXW32_RS08400	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW32_RS08410	COG0489	protein tyrosine kinase activity
EXW32_RS08415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW32_RS08420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW32_RS08425	COG0741	lytic transglycosylase activity
EXW32_RS08435	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW32_RS08440	COG1776	CheC inhibitor of MCP methylation
EXW32_RS08440	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW32_RS08450	COG1338	Plays a role in the flagellum-specific transport system
EXW32_RS08455	COG1987	bacterial-type flagellum assembly
EXW32_RS08465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW32_RS08470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW32_RS08475	COG1419	protein localization to endoplasmic reticulum
EXW32_RS08480	COG4786	Flagellar basal body rod
EXW32_RS08485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW32_RS08515	COG0412	Dienelactone hydrolase
EXW32_RS08520	COG2329	Antibiotic biosynthesis monooxygenase
EXW32_RS08535	COG2814	Major facilitator Superfamily
EXW32_RS08545	COG0583	DNA-binding transcription factor activity
EXW32_RS08550	COG3842	ATPase activity
EXW32_RS08600	COG0406	alpha-ribazole phosphatase activity
EXW32_RS08630	COG0367	asparagine synthase
EXW32_RS08660	COG1802	Transcriptional regulator
EXW32_RS08665	COG0697	spore germination
EXW32_RS08675	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS08675	COG1216	Glycosyl transferase, family 2
EXW32_RS08680	COG1757	Na H antiporter
EXW32_RS08690	COG0277	FAD linked oxidase domain protein
EXW32_RS08710	COG0534	Mate efflux family protein
EXW32_RS08715	COG3340	Belongs to the peptidase S51 family
EXW32_RS08735	COG0785	Cytochrome C biogenesis protein
EXW32_RS08740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS08755	COG3048	D-serine ammonia-lyase activity
EXW32_RS08760	COG2733	membrane
EXW32_RS08795	COG1131	(ABC) transporter
EXW32_RS08810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW32_RS08815	COG0528	UMP kinase activity
EXW32_RS08825	COG1027	Aspartate ammonia-lyase
EXW32_RS08830	COG0281	malic enzyme
EXW32_RS08835	COG4191	Histidine kinase
EXW32_RS08840	COG0784	Response regulator, receiver
EXW32_RS08845	COG1846	Transcriptional regulator
EXW32_RS08855	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW32_RS08865	COG2502	aspartate--ammonia ligase
EXW32_RS08900	COG1051	belongs to the nudix hydrolase family
EXW32_RS08905	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS08915	COG2814	Major facilitator Superfamily
EXW32_RS08940	COG1695	Transcriptional regulator
EXW32_RS08950	COG2814	Major facilitator Superfamily
EXW32_RS08955	COG0640	Transcriptional regulator
EXW32_RS08960	COG0477	Major facilitator Superfamily
EXW32_RS08965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW32_RS08975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW32_RS08980	COG2223	nitrite transmembrane transporter activity
EXW32_RS08985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW32_RS08995	COG2244	polysaccharide biosynthetic process
EXW32_RS09000	COG0733	neurotransmitter:sodium symporter activity
EXW32_RS09010	COG5566	PFAM Mor transcription activator
EXW32_RS09015	COG2323	membrane
EXW32_RS09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW32_RS09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS09045	COG0028	Belongs to the TPP enzyme family
EXW32_RS09060	COG0129	dihydroxy-acid dehydratase activity
EXW32_RS09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW32_RS09090	COG2814	Major facilitator Superfamily
EXW32_RS09095	COG3384	dioxygenase
EXW32_RS09120	COG4166	transmembrane transport
EXW32_RS09145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS09165	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW32_RS09170	COG1054	Belongs to the UPF0176 family
EXW32_RS09180	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW32_RS09185	COG0531	amino acid
EXW32_RS09220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW32_RS09235	COG4257	antibiotic catabolic process
EXW32_RS09240	COG2390	Transcriptional regulator
EXW32_RS09250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW32_RS09255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS09260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW32_RS09275	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW32_RS09290	COG0583	DNA-binding transcription factor activity
EXW32_RS09310	COG0006	proline dipeptidase activity
EXW32_RS09325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW32_RS09345	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS09355	COG4641	Protein conserved in bacteria
EXW32_RS09365	COG1276	copper resistance
EXW32_RS09365	COG2372	response to copper ion
EXW32_RS09370	COG4549	nuclear export factor GLE1
EXW32_RS09380	COG0697	spore germination
EXW32_RS09385	COG0583	DNA-binding transcription factor activity
EXW32_RS09390	COG1959	2 iron, 2 sulfur cluster binding
EXW32_RS09395	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW32_RS09400	COG0778	Nitroreductase
EXW32_RS09420	COG0628	permease
EXW32_RS09435	COG1231	oxidoreductase activity
EXW32_RS09440	COG0523	cobalamin synthesis protein
EXW32_RS09450	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS09455	COG2030	dehydratase
EXW32_RS09460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW32_RS09475	COG0411	ABC transporter
EXW32_RS09495	COG0583	DNA-binding transcription factor activity
EXW32_RS09505	COG1942	4-Oxalocrotonate Tautomerase
EXW32_RS09520	COG0346	lactoylglutathione lyase activity
EXW32_RS09530	COG1271	oxidase subunit
EXW32_RS09535	COG1294	oxidase, subunit
EXW32_RS09540	COG4988	ABC transporter
EXW32_RS09545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW32_RS09575	COG1686	Belongs to the peptidase S11 family
EXW32_RS09590	COG1388	LysM domain
EXW32_RS09590	COG0791	NLP P60 protein
EXW32_RS09600	COG1132	(ABC) transporter
EXW32_RS09605	COG0745	RESPONSE REGULATOR receiver
EXW32_RS09610	COG5002	protein histidine kinase activity
EXW32_RS09615	COG0300	oxidoreductase activity
EXW32_RS09620	COG4122	O-methyltransferase activity
EXW32_RS09640	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EXW32_RS09650	COG0460	homoserine dehydrogenase
EXW32_RS09660	COG0083	homoserine kinase activity
EXW32_RS09675	COG1316	TRANSCRIPTIONal
EXW32_RS09695	COG1285	pathogenesis
EXW32_RS09700	COG1247	-acetyltransferase
EXW32_RS09720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW32_RS09730	COG1082	Xylose isomerase domain protein TIM barrel
EXW32_RS09740	COG2814	Major facilitator Superfamily
EXW32_RS09745	COG1279	arginine transmembrane transporter activity
EXW32_RS09750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS09760	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW32_RS09790	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW32_RS09795	COG0577	efflux transmembrane transporter activity
EXW32_RS09800	COG2002	toxin-antitoxin pair type II binding
EXW32_RS09805	COG1404	Belongs to the peptidase S8 family
EXW32_RS09815	COG3842	ATPase activity
EXW32_RS09820	COG2508	Transcriptional regulator
EXW32_RS09830	COG1653	transport
EXW32_RS09835	COG1175	transmembrane transport
EXW32_RS09840	COG0395	ABC-type sugar transport system, permease component
EXW32_RS09845	COG5426	von Willebrand factor, type A
EXW32_RS09855	COG1940	carbohydrate kinase activity
EXW32_RS09860	COG2222	sugar isomerase
EXW32_RS09870	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW32_RS09875	COG3684	Belongs to the aldolase LacD family
EXW32_RS09880	COG0366	Alpha amylase catalytic
EXW32_RS09885	COG0366	Alpha amylase catalytic
EXW32_RS09890	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW32_RS09895	COG0640	Transcriptional regulator
EXW32_RS09900	COG0667	Aldo Keto reductase
EXW32_RS09945	COG3949	Membrane
EXW32_RS09950	COG0783	Belongs to the Dps family
EXW32_RS09965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW32_RS09975	COG1231	oxidoreductase activity
EXW32_RS09980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS09985	COG4989	oxidoreductase activity
EXW32_RS09990	COG0523	cobalamin synthesis protein
EXW32_RS09995	COG0456	acetyltransferase
EXW32_RS10000	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW32_RS10015	COG1902	pentaerythritol trinitrate reductase activity
EXW32_RS10020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW32_RS10030	COG4166	transmembrane transport
EXW32_RS10035	COG0346	lactoylglutathione lyase activity
EXW32_RS10045	COG0406	alpha-ribazole phosphatase activity
EXW32_RS10055	COG5337	Spore coat protein CotH
EXW32_RS10060	COG1051	belongs to the nudix hydrolase family
EXW32_RS10065	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS10070	COG2244	polysaccharide biosynthetic process
EXW32_RS10080	COG0701	Predicted permease
EXW32_RS10085	COG3689	TIGRFAM TIGR03943 family protein
EXW32_RS10090	COG1607	acyl-coa hydrolase
EXW32_RS10100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW32_RS10115	COG0702	epimerase
EXW32_RS10120	COG2839	Protein conserved in bacteria
EXW32_RS10125	COG1253	flavin adenine dinucleotide binding
EXW32_RS10140	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS10145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW32_RS10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS10170	COG1876	peptidase activity
EXW32_RS10185	COG2211	Major facilitator Superfamily
EXW32_RS10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS10210	COG0561	phosphatase activity
EXW32_RS10220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW32_RS10235	COG1819	glycosyl
EXW32_RS10240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS10270	COG0456	acetyltransferase
EXW32_RS10305	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW32_RS10350	COG3874	Sporulation protein YtfJ
EXW32_RS10375	COG2226	methyltransferase
EXW32_RS10400	COG0346	lactoylglutathione lyase activity
EXW32_RS10410	COG0604	alcohol dehydrogenase
EXW32_RS10415	COG1595	DNA-templated transcription, initiation
EXW32_RS10440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW32_RS10440	COG0426	domain, Protein
EXW32_RS10450	COG0386	Belongs to the glutathione peroxidase family
EXW32_RS10455	COG1305	Transglutaminase-like
EXW32_RS10460	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW32_RS10465	COG0714	Associated with various cellular activities
EXW32_RS10470	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW32_RS10475	COG1140	nitrate reductase beta subunit
EXW32_RS10480	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW32_RS10485	COG2181	nitrate reductase activity
EXW32_RS10490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW32_RS10495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW32_RS10500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW32_RS10505	COG0303	'Molybdopterin
EXW32_RS10510	COG0314	molybdopterin synthase activity
EXW32_RS10520	COG2223	nitrite transmembrane transporter activity
EXW32_RS10540	COG1648	precorrin-2 dehydrogenase activity
EXW32_RS10550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW32_RS10550	COG1587	Uroporphyrinogen-III synthase
EXW32_RS10555	COG2146	nitrite reductase [NAD(P)H] activity
EXW32_RS10560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW32_RS10565	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW32_RS10595	COG2359	stage V sporulation protein S
EXW32_RS10640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS10660	COG1418	mRNA catabolic process
EXW32_RS10665	COG0488	(ABC) transporter
EXW32_RS10685	COG1413	lyase activity
EXW32_RS10700	COG2521	methyltransferase
EXW32_RS10700	COG2136	Putative SAM-dependent methyltransferase
EXW32_RS10705	COG0018	arginyl-trna synthetase
EXW32_RS10755	COG0017	Asparaginyl-tRNA synthetase
EXW32_RS10760	COG0733	neurotransmitter:sodium symporter activity
EXW32_RS10785	COG2610	gluconate transmembrane transporter activity
EXW32_RS10795	COG1794	racemase activity, acting on amino acids and derivatives
EXW32_RS10805	COG0456	acetyltransferase
EXW32_RS10810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW32_RS10820	COG1131	(ABC) transporter
EXW32_RS10835	COG0546	phosphoglycolate phosphatase activity
EXW32_RS10850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS10865	COG0768	penicillin binding
EXW32_RS10875	COG0204	Acyl-transferase
EXW32_RS10880	COG1272	protein, Hemolysin III
EXW32_RS10885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW32_RS10890	COG0805	protein transport
EXW32_RS10905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW32_RS10910	COG1999	signal sequence binding
EXW32_RS10915	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW32_RS10920	COG0367	asparagine synthase
EXW32_RS10935	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS10945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS10965	COG1335	isochorismatase
EXW32_RS10975	COG0668	transmembrane transport
EXW32_RS10980	COG2203	Gaf domain
EXW32_RS10980	COG4585	Histidine kinase
EXW32_RS10985	COG2197	response regulator
EXW32_RS10990	COG1737	Transcriptional regulator
EXW32_RS10995	COG1064	alcohol dehydrogenase
EXW32_RS11010	COG1070	Carbohydrate kinase
EXW32_RS11020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW32_RS11040	COG0517	IMP dehydrogenase activity
EXW32_RS11040	COG1125	glycine betaine transport
EXW32_RS11045	COG1174	glycine betaine transport
EXW32_RS11080	COG1253	flavin adenine dinucleotide binding
EXW32_RS11085	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS11090	COG5506	Protein of unknown function (DUF1694)
EXW32_RS11105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS11110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW32_RS11115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW32_RS11120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW32_RS11125	COG0456	acetyltransferase
EXW32_RS11130	COG3829	transcription factor binding
EXW32_RS11135	COG1509	lysine 2,3-aminomutase activity
EXW32_RS11145	COG4479	Belongs to the UPF0346 family
EXW32_RS11170	COG4991	sh3 domain protein
EXW32_RS11170	COG0515	serine threonine protein kinase
EXW32_RS11170	COG3064	Membrane
EXW32_RS11180	COG0671	phosphoesterase, PA-phosphatase related
EXW32_RS11185	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW32_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS11245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW32_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS11290	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW32_RS11290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS11300	COG2814	Major facilitator Superfamily
EXW32_RS11310	COG0372	Belongs to the citrate synthase family
EXW32_RS11315	COG2079	MmgE PrpD family protein
EXW32_RS11320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW32_RS11325	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS11330	COG2084	Dehydrogenase
EXW32_RS11335	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS11340	COG1280	lysine exporter protein (LysE YggA)
EXW32_RS11345	COG1024	Enoyl-CoA hydratase
EXW32_RS11360	COG0420	3'-5' exonuclease activity
EXW32_RS11385	COG2223	nitrite transmembrane transporter activity
EXW32_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS11395	COG1169	isochorismate synthase
EXW32_RS11400	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW32_RS11405	COG1535	isochorismatase
EXW32_RS11405	COG3433	isochorismatase activity
EXW32_RS11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW32_RS11415	COG3251	PFAM MbtH domain protein
EXW32_RS11420	COG2814	Major facilitator Superfamily
EXW32_RS11435	COG0776	regulation of translation
EXW32_RS11445	COG2318	DinB family
EXW32_RS11450	COG1115	amino acid carrier protein
EXW32_RS11465	COG2329	Antibiotic biosynthesis monooxygenase
EXW32_RS11475	COG1187	pseudouridine synthase activity
EXW32_RS11480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW32_RS11485	COG3655	Transcriptional regulator
EXW32_RS11495	COG1136	(ABC) transporter
EXW32_RS11505	COG0596	Alpha beta hydrolase
EXW32_RS11520	COG0028	Belongs to the TPP enzyme family
EXW32_RS11545	COG1253	flavin adenine dinucleotide binding
EXW32_RS11600	COG1846	Transcriptional regulator
EXW32_RS11610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS11615	COG1309	transcriptional regulator
EXW32_RS11645	COG1247	-acetyltransferase
EXW32_RS11675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW32_RS11685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS11715	COG0583	DNA-binding transcription factor activity
EXW32_RS11720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW32_RS11735	COG0583	DNA-binding transcription factor activity
EXW32_RS11740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW32_RS11745	COG2258	MOSC domain
EXW32_RS11760	COG1132	(ABC) transporter
EXW32_RS11765	COG1132	(ABC) transporter
EXW32_RS11780	COG0189	ligase activity
EXW32_RS11805	COG1396	sequence-specific DNA binding
EXW32_RS11840	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW32_RS11845	COG1595	DNA-templated transcription, initiation
EXW32_RS11925	COG2755	lipolytic protein G-D-S-L family
EXW32_RS11925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW32_RS11935	COG2169	Transcriptional regulator
EXW32_RS11945	COG0673	inositol 2-dehydrogenase activity
EXW32_RS12005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW32_RS12010	COG2971	BadF BadG BcrA BcrD
EXW32_RS12020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW32_RS12060	COG1309	transcriptional regulator
EXW32_RS12075	COG1136	(ABC) transporter
EXW32_RS12080	COG0500	methyltransferase
EXW32_RS12080	COG3615	Tellurite resistance protein tehB
EXW32_RS12090	COG0693	protein deglycase activity
EXW32_RS12100	COG0588	phosphoglycerate mutase activity
EXW32_RS12125	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW32_RS12135	COG0110	maltose O-acetyltransferase activity
EXW32_RS12140	COG1136	(ABC) transporter
EXW32_RS12165	COG1686	Belongs to the peptidase S11 family
EXW32_RS12190	COG0768	penicillin binding
EXW32_RS12195	COG0745	RESPONSE REGULATOR receiver
EXW32_RS12200	COG2205	protein histidine kinase activity
EXW32_RS12205	COG1136	(ABC) transporter
EXW32_RS12210	COG0577	efflux transmembrane transporter activity
EXW32_RS12220	COG1595	DNA-templated transcription, initiation
EXW32_RS12230	COG0768	penicillin binding
EXW32_RS12235	COG0768	penicillin binding
EXW32_RS12255	COG1252	NADH dehydrogenase
EXW32_RS12260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS12260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS12275	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW32_RS12275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS12295	COG1136	(ABC) transporter
EXW32_RS12300	COG0577	efflux transmembrane transporter activity
EXW32_RS12320	COG1136	(ABC) transporter
EXW32_RS12335	COG2723	6-phospho-beta-galactosidase activity
EXW32_RS12405	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS12415	COG2239	Acts as a magnesium transporter
EXW32_RS12445	COG0697	spore germination
EXW32_RS12470	COG3397	chitin binding
EXW32_RS12475	COG0823	Involved in the tonB-independent uptake of proteins
EXW32_RS12485	COG1408	metallophosphoesterase
EXW32_RS12495	COG1131	(ABC) transporter
EXW32_RS12505	COG1309	transcriptional regulator
EXW32_RS12515	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS12520	COG0439	Biotin carboxylase
EXW32_RS12525	COG0511	ligase activity, forming carbon-carbon bonds
EXW32_RS12530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW32_RS12535	COG1024	Enoyl-CoA hydratase
EXW32_RS12540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW32_RS12545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW32_RS12560	COG3344	reverse transcriptase
EXW32_RS12595	COG0572	uridine kinase
EXW32_RS12630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW32_RS12655	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW32_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS12690	COG1733	regulation of RNA biosynthetic process
EXW32_RS12715	COG1309	transcriptional regulator
EXW32_RS12745	COG0697	spore germination
EXW32_RS12750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS12785	COG2323	membrane
EXW32_RS12800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS12805	COG0697	spore germination
EXW32_RS12825	COG0201	protein transport
EXW32_RS12835	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS12840	COG3227	Zinc metalloprotease (Elastase)
EXW32_RS12845	COG1523	belongs to the glycosyl hydrolase 13 family
EXW32_RS12860	COG0076	glutamate decarboxylase activity
EXW32_RS12865	COG0657	acetylesterase activity
EXW32_RS12870	COG1073	alpha beta
EXW32_RS12880	COG0577	efflux transmembrane transporter activity
EXW32_RS12885	COG1136	(ABC) transporter
EXW32_RS12915	COG5002	protein histidine kinase activity
EXW32_RS12920	COG0745	RESPONSE REGULATOR receiver
EXW32_RS12925	COG1011	Hydrolase
EXW32_RS12950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW32_RS12955	COG1183	phosphatidylcholine synthase activity
EXW32_RS12965	COG1132	(ABC) transporter
EXW32_RS12970	COG3961	Belongs to the TPP enzyme family
EXW32_RS12990	COG0322	excinuclease ABC activity
EXW32_RS13015	COG2318	DinB family
EXW32_RS13030	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW32_RS13055	COG3878	Protein conserved in bacteria
EXW32_RS13080	COG1051	belongs to the nudix hydrolase family
EXW32_RS13085	COG0592	DNA-directed DNA polymerase activity
EXW32_RS13090	COG2816	NAD+ diphosphatase activity
EXW32_RS13100	COG2223	nitrite transmembrane transporter activity
EXW32_RS13110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS13120	COG0494	nUDIX hydrolase
EXW32_RS13140	COG0697	spore germination
EXW32_RS13145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS13155	COG0584	glycerophosphoryl diester phosphodiesterase
EXW32_RS13170	COG2814	Major facilitator Superfamily
EXW32_RS13210	COG0768	penicillin binding
EXW32_RS13215	COG0671	phosphoesterase, PA-phosphatase related
EXW32_RS13220	COG0604	alcohol dehydrogenase
EXW32_RS13225	COG5002	protein histidine kinase activity
EXW32_RS13230	COG0745	RESPONSE REGULATOR receiver
EXW32_RS13240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW32_RS13250	COG2205	protein histidine kinase activity
EXW32_RS13265	COG1122	ATPase activity
EXW32_RS13270	COG4720	Psort location CytoplasmicMembrane, score
EXW32_RS13275	COG1794	racemase activity, acting on amino acids and derivatives
EXW32_RS13280	COG1819	glycosyl
EXW32_RS13290	COG0768	penicillin binding
EXW32_RS13295	COG5002	protein histidine kinase activity
EXW32_RS13300	COG0561	phosphatase activity
EXW32_RS13345	COG2124	cytochrome p450
EXW32_RS13390	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW32_RS13400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS13405	COG0460	homoserine dehydrogenase
EXW32_RS13425	COG0577	efflux transmembrane transporter activity
EXW32_RS13430	COG1136	(ABC) transporter
EXW32_RS13440	COG0488	(ABC) transporter
EXW32_RS13445	COG0667	Aldo Keto reductase
EXW32_RS13450	COG0583	DNA-binding transcription factor activity
EXW32_RS13455	COG2205	protein histidine kinase activity
EXW32_RS13460	COG0745	RESPONSE REGULATOR receiver
EXW32_RS13470	COG3773	Cell wall hydrolase
EXW32_RS13475	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW32_RS13525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS13540	COG2959	enzyme of heme biosynthesis
EXW32_RS13565	COG3483	tryptophan 2,3-dioxygenase activity
EXW32_RS13570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW32_RS13575	COG3844	kynureninase activity
EXW32_RS13580	COG1309	transcriptional regulator
EXW32_RS13595	COG3284	Transcriptional regulator
EXW32_RS13610	COG1349	DNA-binding transcription factor activity
EXW32_RS13630	COG1959	2 iron, 2 sulfur cluster binding
EXW32_RS13645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW32_RS13650	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW32_RS13655	COG0022	dehydrogenase e1 component
EXW32_RS13660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW32_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS13685	COG0456	acetyltransferase
EXW32_RS13685	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW32_RS13720	COG4176	ABC-type proline glycine betaine transport system permease component
EXW32_RS13725	COG4175	Glycine betaine
EXW32_RS13725	COG0517	IMP dehydrogenase activity
EXW32_RS13750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW32_RS13755	COG2153	protein acetylation
EXW32_RS13760	COG3397	chitin binding
EXW32_RS13770	COG1819	glycosyl
EXW32_RS13785	COG2205	protein histidine kinase activity
EXW32_RS13790	COG2315	Protein conserved in bacteria
EXW32_RS13840	COG3973	AAA domain
EXW32_RS13850	COG2105	PFAM AIG2 family protein
EXW32_RS13855	COG0514	ATP-dependent DNA helicase (RecQ)
EXW32_RS13880	COG4637	Psort location Cytoplasmic, score
EXW32_RS13890	COG1227	inorganic diphosphatase activity
EXW32_RS13895	COG3397	chitin binding
EXW32_RS13900	COG2318	DinB family
EXW32_RS13920	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW32_RS13925	COG1115	amino acid carrier protein
EXW32_RS13930	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS13935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW32_RS13945	COG3938	Belongs to the proline racemase family
EXW32_RS13950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW32_RS13990	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS14005	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW32_RS14010	COG4166	transmembrane transport
EXW32_RS14020	COG4948	Mandelate Racemase Muconate Lactonizing
EXW32_RS14040	COG0667	Aldo Keto reductase
EXW32_RS14085	COG2936	dipeptidyl-peptidase activity
EXW32_RS14095	COG0745	RESPONSE REGULATOR receiver
EXW32_RS14115	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW32_RS14120	COG1164	Oligoendopeptidase f
EXW32_RS14135	COG1307	EDD domain protein, DegV family
EXW32_RS14160	COG1335	isochorismatase
EXW32_RS14175	COG2814	Major facilitator Superfamily
EXW32_RS14185	COG1664	Polymer-forming cytoskeletal
EXW32_RS14190	COG0789	Transcriptional regulator
EXW32_RS14195	COG4533	DNA binding
EXW32_RS14200	COG2814	Major facilitator Superfamily
EXW32_RS14200	COG0477	Major facilitator Superfamily
EXW32_RS14220	COG2261	transglycosylase associated protein
EXW32_RS14235	COG2226	methyltransferase
EXW32_RS14270	COG0436	Aminotransferase
EXW32_RS14275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW32_RS14305	COG1131	(ABC) transporter
EXW32_RS14360	COG0628	permease
EXW32_RS14405	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW32_RS14415	COG0697	spore germination
EXW32_RS14420	COG2318	DinB family
EXW32_RS14470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW32_RS14480	COG2814	Major facilitator Superfamily
EXW32_RS14485	COG1368	sulfuric ester hydrolase activity
EXW32_RS14500	COG0488	(ABC) transporter
EXW32_RS14505	COG2409	Drug exporters of the RND superfamily
EXW32_RS14505	COG1033	growth of symbiont in host cell
EXW32_RS14510	COG1309	transcriptional regulator
EXW32_RS14515	COG0494	nUDIX hydrolase
EXW32_RS14535	COG0287	Prephenate dehydrogenase
EXW32_RS14550	COG1605	Chorismate mutase
EXW32_RS14550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW32_RS14585	COG1388	LysM domain
EXW32_RS14585	COG3584	3D domain protein
EXW32_RS14595	COG0346	lactoylglutathione lyase activity
EXW32_RS14605	COG0431	NADPH-dependent FMN reductase
EXW32_RS14635	COG0579	oxidoreductase
EXW32_RS14640	COG1879	ABC-type sugar transport system periplasmic component
EXW32_RS14655	COG1129	ABC transporter
EXW32_RS14660	COG2390	Transcriptional regulator
EXW32_RS14680	COG2226	methyltransferase
EXW32_RS14700	COG2329	Antibiotic biosynthesis monooxygenase
EXW32_RS14730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS14735	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW32_RS14740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW32_RS14745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW32_RS14750	COG3239	Fatty acid desaturase
EXW32_RS14775	COG3842	ATPase activity
EXW32_RS14800	COG1175	transmembrane transport
EXW32_RS14805	COG1349	DNA-binding transcription factor activity
EXW32_RS14815	COG3655	Transcriptional regulator
EXW32_RS14830	COG4377	Putative membrane peptidase family (DUF2324)
EXW32_RS14850	COG3279	Response regulator of the LytR AlgR family
EXW32_RS14865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS14870	COG0346	lactoylglutathione lyase activity
EXW32_RS14895	COG0714	Associated with various cellular activities
EXW32_RS14915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW32_RS14920	COG0753	catalase activity
EXW32_RS14930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW32_RS14950	COG0778	Nitroreductase
EXW32_RS14955	COG1846	Transcriptional regulator
EXW32_RS14990	COG1725	Transcriptional regulator
EXW32_RS15020	COG2207	Transcriptional regulator
EXW32_RS15025	COG0456	acetyltransferase
EXW32_RS15040	COG0697	spore germination
EXW32_RS15045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS15080	COG0814	amino acid
EXW32_RS15085	COG0697	spore germination
EXW32_RS15105	COG0745	RESPONSE REGULATOR receiver
EXW32_RS15110	COG0596	Alpha beta hydrolase
EXW32_RS15120	COG0456	acetyltransferase
EXW32_RS15120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW32_RS15145	COG0730	response to heat
EXW32_RS15155	COG0833	amino acid
EXW32_RS15165	COG4335	DNA alkylation repair
EXW32_RS15195	COG0768	penicillin binding
EXW32_RS15210	COG3104	oligopeptide transport
EXW32_RS15215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW32_RS15230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW32_RS15235	COG1984	allophanate hydrolase subunit 2
EXW32_RS15240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW32_RS15245	COG1414	Transcriptional regulator
EXW32_RS15255	COG3142	Participates in the control of copper homeostasis
EXW32_RS15260	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS15285	COG0640	Transcriptional regulator
EXW32_RS15295	COG3314	Sporulation integral membrane protein YlbJ
EXW32_RS15315	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW32_RS15320	COG0577	efflux transmembrane transporter activity
EXW32_RS15325	COG0577	efflux transmembrane transporter activity
EXW32_RS15330	COG1136	(ABC) transporter
EXW32_RS15365	COG0574	Belongs to the PEP-utilizing enzyme family
EXW32_RS15365	COG3848	Pyruvate phosphate dikinase
EXW32_RS15375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW32_RS15400	COG5002	protein histidine kinase activity
EXW32_RS15405	COG0745	RESPONSE REGULATOR receiver
EXW32_RS15415	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW32_RS15435	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW32_RS15440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW32_RS15445	COG1121	(ABC) transporter
EXW32_RS15465	COG0798	PFAM Bile acid sodium symporter
EXW32_RS15470	COG0346	lactoylglutathione lyase activity
EXW32_RS15475	COG0640	Transcriptional regulator
EXW32_RS15490	COG1309	transcriptional regulator
EXW32_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS15500	COG1522	sequence-specific DNA binding
EXW32_RS15515	COG0346	lactoylglutathione lyase activity
EXW32_RS15525	COG0519	Catalyzes the synthesis of GMP from XMP
EXW32_RS15555	COG0745	RESPONSE REGULATOR receiver
EXW32_RS15560	COG5002	protein histidine kinase activity
EXW32_RS15560	COG3850	Histidine kinase
EXW32_RS15590	COG1073	alpha beta
EXW32_RS15595	COG0814	amino acid
EXW32_RS15600	COG1760	l-serine dehydratase
EXW32_RS15605	COG1760	l-serine dehydratase
EXW32_RS15615	COG5002	protein histidine kinase activity
EXW32_RS15620	COG0745	RESPONSE REGULATOR receiver
EXW32_RS15630	COG5002	protein histidine kinase activity
EXW32_RS15655	COG4977	sequence-specific DNA binding
EXW32_RS15690	COG2814	Major facilitator Superfamily
EXW32_RS15705	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW32_RS15730	COG1522	sequence-specific DNA binding
EXW32_RS15740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW32_RS15755	COG1136	(ABC) transporter
EXW32_RS15760	COG0577	efflux transmembrane transporter activity
EXW32_RS15780	COG5002	protein histidine kinase activity
EXW32_RS15780	COG3850	Histidine kinase
EXW32_RS15790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS15810	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW32_RS15830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW32_RS15865	COG2814	Major facilitator Superfamily
EXW32_RS15950	COG0477	Major facilitator Superfamily
EXW32_RS15965	COG1846	Transcriptional regulator
EXW32_RS15970	COG2814	Major facilitator Superfamily
EXW32_RS16005	COG0640	Transcriptional regulator
EXW32_RS16030	COG1329	Transcriptional regulator
EXW32_RS16085	COG5002	protein histidine kinase activity
EXW32_RS16100	COG1136	(ABC) transporter
EXW32_RS16115	COG1131	(ABC) transporter
EXW32_RS16195	COG0789	Transcriptional regulator
EXW32_RS16240	COG4187	Peptidase family M20/M25/M40
EXW32_RS16255	COG2031	fatty acid transporter
EXW32_RS16265	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW32_RS16315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW32_RS16320	COG1288	antiporter activity
EXW32_RS16325	COG2356	endonuclease I
EXW32_RS16330	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW32_RS16350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW32_RS16370	COG1785	Belongs to the alkaline phosphatase family
EXW32_RS16375	COG0778	Nitroreductase
EXW32_RS16380	COG1733	regulation of RNA biosynthetic process
EXW32_RS16395	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS16405	COG1131	(ABC) transporter
EXW32_RS16435	COG1595	DNA-templated transcription, initiation
EXW32_RS16450	COG1011	Hydrolase
EXW32_RS16455	COG2365	Tyrosine phosphatase family
EXW32_RS16480	COG0346	lactoylglutathione lyase activity
EXW32_RS16485	COG1940	carbohydrate kinase activity
EXW32_RS16490	COG0738	Major facilitator superfamily
EXW32_RS16495	COG0110	maltose O-acetyltransferase activity
EXW32_RS16510	COG0628	permease
EXW32_RS16515	COG2261	transglycosylase associated protein
EXW32_RS16530	COG1720	tRNA m6t6A37 methyltransferase activity
EXW32_RS16535	COG0500	methyltransferase
EXW32_RS16545	COG0477	Major facilitator Superfamily
EXW32_RS16560	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW32_RS16570	COG1253	flavin adenine dinucleotide binding
EXW32_RS16575	COG0789	Transcriptional regulator
EXW32_RS16585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW32_RS16610	COG0697	spore germination
EXW32_RS16615	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW32_RS16620	COG3813	Protein conserved in bacteria
EXW32_RS16625	COG2706	6-phosphogluconolactonase activity
EXW32_RS16630	COG1070	Carbohydrate kinase
EXW32_RS16640	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW32_RS16645	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW32_RS16660	COG0814	amino acid
EXW32_RS16680	COG1393	Belongs to the ArsC family
EXW32_RS16690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS16705	COG0494	nUDIX hydrolase
EXW32_RS16720	COG0384	phenazine biosynthesis protein PhzF
EXW32_RS16730	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS16735	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW32_RS16740	COG1733	regulation of RNA biosynthetic process
EXW32_RS16755	COG1191	sigma factor activity
EXW32_RS16770	COG1876	peptidase activity
EXW32_RS16810	COG0741	lytic transglycosylase activity
EXW32_RS16835	COG5002	protein histidine kinase activity
EXW32_RS16875	COG0814	amino acid
EXW32_RS16900	COG1151	hydroxylamine reductase activity
EXW32_RS16925	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS16935	COG2072	flavoprotein involved in K transport
EXW32_RS16980	COG1695	Transcriptional regulator
EXW32_RS16985	COG0604	alcohol dehydrogenase
EXW32_RS16990	COG1113	amino acid transport
EXW32_RS17000	COG2814	Major facilitator Superfamily
EXW32_RS17010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS17015	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS17025	COG0534	Mate efflux family protein
EXW32_RS17030	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS17035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW32_RS17050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW32_RS17055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW32_RS17075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS17080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS17085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS17090	COG3739	integral membrane protein
EXW32_RS17110	COG0583	DNA-binding transcription factor activity
EXW32_RS17135	COG1193	negative regulation of DNA recombination
EXW32_RS17155	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW32_RS17160	COG1164	Oligoendopeptidase f
EXW32_RS17165	COG2957	Belongs to the agmatine deiminase family
EXW32_RS17185	COG3781	membrane
EXW32_RS17200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS17225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW32_RS17230	COG0640	Transcriptional regulator
EXW32_RS17235	COG0604	alcohol dehydrogenase
EXW32_RS17240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW32_RS17245	COG0457	Tetratricopeptide repeat
EXW32_RS17255	COG2808	Putative FMN-binding domain
EXW32_RS17260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW32_RS17270	COG0277	FAD linked oxidase domain protein
EXW32_RS17290	COG1285	pathogenesis
EXW32_RS17300	COG2514	catechol 2,3-dioxygenase activity
EXW32_RS17305	COG2720	vancomycin resistance protein
EXW32_RS17330	COG1278	Cold shock
EXW32_RS17340	COG0716	FMN binding
EXW32_RS17350	COG0494	nUDIX hydrolase
EXW32_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS17380	COG0165	Argininosuccinate lyase
EXW32_RS17410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS17415	COG4145	pantothenate transmembrane transporter activity
EXW32_RS17425	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS17440	COG1657	PFAM Prenyltransferase squalene oxidase
EXW32_RS17445	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW32_RS17450	COG2962	Rard protein
EXW32_RS17455	COG3326	Membrane
EXW32_RS17460	COG0531	amino acid
EXW32_RS17495	COG2226	methyltransferase
EXW32_RS17500	COG4166	transmembrane transport
EXW32_RS17505	COG4166	transmembrane transport
EXW32_RS17510	COG4166	transmembrane transport
EXW32_RS17515	COG1316	TRANSCRIPTIONal
EXW32_RS17525	COG1595	DNA-templated transcription, initiation
EXW32_RS17535	COG1131	(ABC) transporter
EXW32_RS17555	COG0673	inositol 2-dehydrogenase activity
EXW32_RS17560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW32_RS17565	COG0187	DNA topoisomerase II activity
EXW32_RS17570	COG1832	CoA-binding protein
EXW32_RS17575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW32_RS17580	COG0745	RESPONSE REGULATOR receiver
EXW32_RS17590	COG1328	CTP reductase activity
EXW32_RS17600	COG4841	protein insertion into membrane
EXW32_RS17605	COG0824	Thioesterase
EXW32_RS17630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS17645	COG1132	(ABC) transporter
EXW32_RS17650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW32_RS17680	COG2211	Major facilitator Superfamily
EXW32_RS17690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW32_RS17705	COG0183	Belongs to the thiolase family
EXW32_RS17710	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS17715	COG1268	BioY protein
EXW32_RS17720	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS17725	COG1396	sequence-specific DNA binding
EXW32_RS17770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS17780	COG5002	protein histidine kinase activity
EXW32_RS17790	COG0400	carboxylic ester hydrolase activity
EXW32_RS17795	COG0346	lactoylglutathione lyase activity
EXW32_RS17800	COG0069	glutamate synthase activity
EXW32_RS17805	COG1902	pentaerythritol trinitrate reductase activity
EXW32_RS17815	COG1329	Transcriptional regulator
EXW32_RS17820	COG0010	Belongs to the arginase family
EXW32_RS17830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW32_RS17835	COG2986	histidine ammonia-lyase
EXW32_RS17845	COG2226	methyltransferase
EXW32_RS17870	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW32_RS17875	COG0785	Cytochrome C biogenesis protein
EXW32_RS17885	COG1473	amidohydrolase
EXW32_RS17890	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW32_RS17895	COG1131	(ABC) transporter
EXW32_RS17905	COG0583	DNA-binding transcription factor activity
EXW32_RS17915	COG1346	cytolysis
EXW32_RS17930	COG0730	response to heat
EXW32_RS17940	COG3409	Peptidoglycan-binding domain 1 protein
EXW32_RS17940	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS17960	COG1132	(ABC) transporter
EXW32_RS17965	COG1132	(ABC) transporter
EXW32_RS17970	COG3763	UPF0154 protein
EXW32_RS17990	COG3639	organic phosphonate transmembrane transporter activity
EXW32_RS18000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW32_RS18005	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS18015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW32_RS18020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW32_RS18035	COG1695	Transcriptional regulator
EXW32_RS18040	COG1132	(ABC) transporter
EXW32_RS18070	COG0367	asparagine synthase
EXW32_RS18075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW32_RS18085	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW32_RS18090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW32_RS18095	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW32_RS18095	COG3420	alginic acid biosynthetic process
EXW32_RS18120	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS18130	COG0463	Glycosyl transferase, family 2
EXW32_RS18130	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW32_RS18135	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS18140	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS18145	COG1086	Polysaccharide biosynthesis protein
EXW32_RS18150	COG0489	protein tyrosine kinase activity
EXW32_RS18155	COG3944	biosynthesis protein
EXW32_RS18160	COG0174	glutamine synthetase
EXW32_RS18165	COG0789	Transcriptional regulator
EXW32_RS18170	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW32_RS18175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW32_RS18180	COG2860	membrane
EXW32_RS18190	COG0464	growth
EXW32_RS18210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW32_RS18220	COG3584	3D domain protein
EXW32_RS18220	COG1388	LysM domain
EXW32_RS18225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW32_RS18225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW32_RS18225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW32_RS18230	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW32_RS18235	COG1349	DNA-binding transcription factor activity
EXW32_RS18240	COG1979	alcohol dehydrogenase
EXW32_RS18245	COG2322	membrane
EXW32_RS18255	COG1113	amino acid transport
EXW32_RS18265	COG1473	amidohydrolase
EXW32_RS18270	COG1408	metallophosphoesterase
EXW32_RS18275	COG2116	formate transmembrane transporter activity
EXW32_RS18290	COG2217	Heavy metal translocating P-type atpase
EXW32_RS18295	COG2608	mercury ion transmembrane transporter activity
EXW32_RS18300	COG1937	Protein conserved in bacteria
EXW32_RS18330	COG4566	intracellular signal transduction
EXW32_RS18335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW32_RS18340	COG2819	hydrolase of the alpha beta superfamily
EXW32_RS18345	COG1120	ATPase activity
EXW32_RS18350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS18355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS18360	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS18365	COG0708	Exodeoxyribonuclease III
EXW32_RS18370	COG2169	Transcriptional regulator
EXW32_RS18375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW32_RS18380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW32_RS18390	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW32_RS18395	COG2364	Membrane
EXW32_RS18405	COG0346	lactoylglutathione lyase activity
EXW32_RS18410	COG5001	Diguanylate cyclase
EXW32_RS18410	COG3300	MHYT domain
EXW32_RS18450	COG1346	cytolysis
EXW32_RS18460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS18465	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW32_RS18465	COG0596	Alpha beta hydrolase
EXW32_RS18470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW32_RS18480	COG2188	Transcriptional regulator
EXW32_RS18485	COG2723	6-phospho-beta-galactosidase activity
EXW32_RS18490	COG0823	Involved in the tonB-independent uptake of proteins
EXW32_RS18495	COG3773	Cell wall hydrolase
EXW32_RS18505	COG1368	sulfuric ester hydrolase activity
EXW32_RS18510	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW32_RS18520	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW32_RS18525	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW32_RS18530	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW32_RS18540	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW32_RS18545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW32_RS18550	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW32_RS18555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW32_RS18555	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW32_RS18565	COG2359	stage V sporulation protein S
EXW32_RS18570	COG1692	metallophosphoesterase
EXW32_RS18575	COG1418	mRNA catabolic process
EXW32_RS18580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW32_RS18585	COG1058	Belongs to the CinA family
EXW32_RS18585	COG1546	Belongs to the CinA family
EXW32_RS18590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW32_RS18595	COG1426	Protein conserved in bacteria
EXW32_RS18610	COG0300	oxidoreductase activity
EXW32_RS18615	COG0612	Peptidase, M16
EXW32_RS18620	COG0612	Peptidase, M16
EXW32_RS18625	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW32_RS18630	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW32_RS18635	COG3845	ABC transporter
EXW32_RS18640	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW32_RS18645	COG2188	Transcriptional regulator
EXW32_RS18655	COG1674	ftsk spoiiie
EXW32_RS18665	COG0740	serine-type endopeptidase activity
EXW32_RS18670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW32_RS18680	COG0527	aspartate kinase activity
EXW32_RS18685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW32_RS18690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW32_RS18695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW32_RS18700	COG1873	PFAM PRC-barrel domain
EXW32_RS18705	COG0612	Peptidase, M16
EXW32_RS18710	COG0726	polysaccharide deacetylase
EXW32_RS18715	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW32_RS18725	COG0196	riboflavin kinase activity
EXW32_RS18735	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW32_RS18740	COG1550	Protein conserved in bacteria
EXW32_RS18745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW32_RS18750	COG1358	cellular component organization or biogenesis
EXW32_RS18755	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW32_RS18760	COG0195	Participates in both transcription termination and antitermination
EXW32_RS18765	COG0779	Required for maturation of 30S ribosomal subunits
EXW32_RS18775	COG0442	prolyl-tRNA aminoacylation
EXW32_RS18780	COG0750	zinc metalloprotease
EXW32_RS18790	COG4589	Belongs to the CDS family
EXW32_RS18800	COG0233	cytoplasmic translational termination
EXW32_RS18805	COG0528	UMP kinase activity
EXW32_RS18810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW32_RS18820	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW32_RS18825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW32_RS18830	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW32_RS18835	COG4974	Belongs to the 'phage' integrase family
EXW32_RS18840	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW32_RS18845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW32_RS18850	COG0758	DNA mediated transformation
EXW32_RS18855	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW32_RS18860	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW32_RS18865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW32_RS18880	COG0335	large ribosomal subunit rRNA binding
EXW32_RS18885	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW32_RS18890	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW32_RS18895	COG1837	Belongs to the UPF0109 family
EXW32_RS18905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW32_RS18915	COG0552	protein localization to endoplasmic reticulum
EXW32_RS18920	COG1196	nuclear chromosome segregation
EXW32_RS18925	COG0571	ribonuclease III activity
EXW32_RS18930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW32_RS18935	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS18940	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW32_RS18945	COG0416	fatty acid biosynthetic process
EXW32_RS18950	COG1349	DNA-binding transcription factor activity
EXW32_RS18950	COG2050	protein possibly involved in aromatic compounds catabolism
EXW32_RS18955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW32_RS18960	COG1461	Dihydroxyacetone kinase
EXW32_RS18965	COG1302	Protein conserved in bacteria
EXW32_RS18980	COG1564	THIamine pyrophosphokinase
EXW32_RS18985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW32_RS18995	COG2815	serine threonine protein kinase
EXW32_RS18995	COG0515	serine threonine protein kinase
EXW32_RS19000	COG0631	protein serine/threonine phosphatase activity
EXW32_RS19005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW32_RS19010	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW32_RS19010	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW32_RS19015	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW32_RS19020	COG0242	peptide deformylase activity
EXW32_RS19025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW32_RS19030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW32_RS19035	COG1758	RNA polymerase activity
EXW32_RS19050	COG1561	YicC-like family, N-terminal region
EXW32_RS19055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW32_RS19065	COG0006	proline dipeptidase activity
EXW32_RS19085	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW32_RS19110	COG0167	dihydroorotate dehydrogenase activity
EXW32_RS19115	COG0543	2 iron, 2 sulfur cluster binding
EXW32_RS19120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW32_RS19130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW32_RS19135	COG0540	Belongs to the ATCase OTCase family
EXW32_RS19145	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW32_RS19150	COG0564	pseudouridine synthase activity
EXW32_RS19155	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW32_RS19165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW32_RS19170	COG3599	regulation of cell shape
EXW32_RS19175	COG2302	S4 RNA-binding domain
EXW32_RS19180	COG0762	integral membrane protein
EXW32_RS19185	COG1799	cell septum assembly
EXW32_RS19190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW32_RS19200	COG1873	PFAM PRC-barrel domain
EXW32_RS19205	COG1191	sigma factor activity
EXW32_RS19210	COG1191	sigma factor activity
EXW32_RS19220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW32_RS19225	COG0849	cell division
EXW32_RS19230	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW32_RS19245	COG0772	Belongs to the SEDS family
EXW32_RS19250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW32_RS19255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW32_RS19260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW32_RS19265	COG0768	penicillin binding
EXW32_RS19270	COG0768	penicillin binding
EXW32_RS19280	COG0275	rRNA processing
EXW32_RS19285	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW32_RS19290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW32_RS19295	COG0454	-acetyltransferase
EXW32_RS19305	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW32_RS19310	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW32_RS19315	COG1323	Belongs to the UPF0348 family
EXW32_RS19320	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW32_RS19325	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW32_RS19330	COG3314	Sporulation integral membrane protein YlbJ
EXW32_RS19340	COG0742	ribosomal rna small subunit methyltransferase
EXW32_RS19350	COG4471	UPF0298 protein
EXW32_RS19355	COG3679	Belongs to the UPF0342 family
EXW32_RS19360	COG0406	alpha-ribazole phosphatase activity
EXW32_RS19375	COG2340	Cysteine-rich secretory protein family
EXW32_RS19385	COG3336	cytochrome c oxidase
EXW32_RS19410	COG0109	protoheme IX farnesyltransferase activity
EXW32_RS19415	COG1612	heme a metabolic process
EXW32_RS19420	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW32_RS19425	COG0772	Belongs to the SEDS family
EXW32_RS19430	COG4838	Belongs to the UPF0358 family
EXW32_RS19435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW32_RS19440	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW32_RS19450	COG4896	Protein conserved in bacteria
EXW32_RS19465	COG1217	gtp-binding protein TYPA
EXW32_RS19475	COG0483	inositol monophosphate 1-phosphatase activity
EXW32_RS19485	COG4493	Belongs to the UPF0637 family
EXW32_RS19490	COG4476	Belongs to the UPF0223 family
EXW32_RS19495	COG1982	Orn Lys Arg decarboxylase major
EXW32_RS19540	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW32_RS19545	COG0022	dehydrogenase e1 component
EXW32_RS19550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW32_RS19565	COG0561	phosphatase activity
EXW32_RS19570	COG5503	Protein of unknown function (DUF1447)
EXW32_RS19575	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW32_RS19580	COG0569	domain protein
EXW32_RS19590	COG1473	amidohydrolase
EXW32_RS19595	COG2171	N-acyltransferase activity
EXW32_RS19600	COG0583	DNA-binding transcription factor activity
EXW32_RS19605	COG0517	IMP dehydrogenase activity
EXW32_RS19615	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW32_RS19625	COG4703	Protein of unknown function (DUF1797)
EXW32_RS19640	COG2200	EAL domain
EXW32_RS19645	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS19650	COG1408	metallophosphoesterase
EXW32_RS19695	COG2814	Major facilitator Superfamily
EXW32_RS19705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW32_RS19715	COG3209	COG3209 Rhs family protein
EXW32_RS19725	COG2205	protein histidine kinase activity
EXW32_RS19735	COG0436	Aminotransferase
EXW32_RS19740	COG1609	Transcriptional regulator
EXW32_RS19745	COG3833	ABC-type maltose transport systems, permease component
EXW32_RS19750	COG1175	transmembrane transport
EXW32_RS19755	COG2182	Extracellular solute-binding protein
EXW32_RS19765	COG0366	Alpha amylase catalytic
EXW32_RS19770	COG3842	ATPase activity
EXW32_RS19810	COG0183	Belongs to the thiolase family
EXW32_RS19845	COG1695	Transcriptional regulator
EXW32_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS19860	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW32_RS19865	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW32_RS19870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW32_RS19875	COG0436	Aminotransferase
EXW32_RS19880	COG1850	ribulose-bisphosphate carboxylase activity
EXW32_RS19885	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW32_RS19890	COG0235	Class ii aldolase
EXW32_RS19895	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW32_RS19910	COG2084	Dehydrogenase
EXW32_RS19920	COG2199	diguanylate cyclase activity
EXW32_RS19925	COG0778	Nitroreductase
EXW32_RS19950	COG1263	PTS System
EXW32_RS19950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW32_RS19950	COG2190	(PTS) system
EXW32_RS19955	COG3711	transcriptional antiterminator
EXW32_RS19965	COG2188	Transcriptional regulator
EXW32_RS19970	COG0363	glucosamine-6-phosphate deaminase activity
EXW32_RS19975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW32_RS19985	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW32_RS19990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW32_RS20000	COG1547	Domain of unknown function (DUF309)
EXW32_RS20010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW32_RS20015	COG4086	secreted protein
EXW32_RS20020	COG0561	phosphatase activity
EXW32_RS20025	COG0697	spore germination
EXW32_RS20040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW32_RS20080	COG1686	Belongs to the peptidase S11 family
EXW32_RS20085	COG1725	Transcriptional regulator
EXW32_RS20090	COG1131	(ABC) transporter
EXW32_RS20110	COG1846	Transcriptional regulator
EXW32_RS20125	COG0598	Magnesium transport protein CorA
EXW32_RS20140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW32_RS20150	COG4974	Belongs to the 'phage' integrase family
EXW32_RS20160	COG0735	belongs to the Fur family
EXW32_RS20165	COG1300	Membrane
EXW32_RS20185	COG0667	Aldo Keto reductase
EXW32_RS20190	COG0656	L-ascorbic acid biosynthetic process
EXW32_RS20195	COG0456	acetyltransferase
EXW32_RS20195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW32_RS20205	COG1525	nuclease
EXW32_RS20205	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS20205	COG4085	toxin activity
EXW32_RS20210	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW32_RS20220	COG0596	Alpha beta hydrolase
EXW32_RS20225	COG2056	Na+-H+ antiporter family
EXW32_RS20230	COG1609	Transcriptional regulator
EXW32_RS20235	COG0456	acetyltransferase
EXW32_RS20240	COG1073	alpha beta
EXW32_RS20255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW32_RS20255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW32_RS20260	COG0307	riboflavin synthase, alpha
EXW32_RS20265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW32_RS20265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW32_RS20280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW32_RS20285	COG4106	trans-aconitate 2-methyltransferase activity
EXW32_RS20290	COG1073	alpha beta
EXW32_RS20290	COG2226	methyltransferase
EXW32_RS20295	COG0156	8-amino-7-oxononanoate synthase activity
EXW32_RS20305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS20315	COG1757	Na H antiporter
EXW32_RS20320	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS20330	COG1522	sequence-specific DNA binding
EXW32_RS20365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW32_RS20375	COG0300	oxidoreductase activity
EXW32_RS20380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS20385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW32_RS20390	COG1760	l-serine dehydratase
EXW32_RS20395	COG1760	l-serine dehydratase
EXW32_RS20405	COG1234	tRNA 3'-trailer cleavage
EXW32_RS20430	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW32_RS20435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS20450	COG1376	ErfK ybiS ycfS ynhG family protein
EXW32_RS20455	COG4129	membrane
EXW32_RS20460	COG1126	abc transporter atp-binding protein
EXW32_RS20465	COG0765	amino acid transport
EXW32_RS20470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW32_RS20480	COG2816	NAD+ diphosphatase activity
EXW32_RS20485	COG2323	membrane
EXW32_RS20490	COG0772	Belongs to the SEDS family
EXW32_RS20495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW32_RS20500	COG0022	dehydrogenase e1 component
EXW32_RS20505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW32_RS20510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW32_RS20515	COG3426	butyrate kinase activity
EXW32_RS20525	COG0280	phosphate acetyltransferase
EXW32_RS20530	COG3290	protein histidine kinase activity
EXW32_RS20530	COG3829	transcription factor binding
EXW32_RS20540	COG0584	glycerophosphoryl diester phosphodiesterase
EXW32_RS20545	COG3093	addiction module antidote protein HigA
EXW32_RS20555	COG0745	RESPONSE REGULATOR receiver
EXW32_RS20560	COG0750	zinc metalloprotease
EXW32_RS20565	COG0497	DNA recombination
EXW32_RS20570	COG1438	arginine binding
EXW32_RS20575	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW32_RS20580	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW32_RS20585	COG0142	geranyltranstransferase activity
EXW32_RS20590	COG1722	exodeoxyribonuclease VII activity
EXW32_RS20595	COG1570	exodeoxyribonuclease VII activity
EXW32_RS20600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW32_RS20605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW32_RS20610	COG1302	Protein conserved in bacteria
EXW32_RS20615	COG0439	Biotin carboxylase
EXW32_RS20620	COG0511	ligase activity, forming carbon-carbon bonds
EXW32_RS20665	COG3854	ATPases associated with a variety of cellular activities
EXW32_RS20685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW32_RS20690	COG0006	proline dipeptidase activity
EXW32_RS20695	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW32_RS20705	COG3872	metal-dependent enzyme
EXW32_RS20715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW32_RS20750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS20760	COG1609	Transcriptional regulator
EXW32_RS20770	COG2076	Multidrug Resistance protein
EXW32_RS20775	COG2076	Multidrug Resistance protein
EXW32_RS20810	COG1725	Transcriptional regulator
EXW32_RS20825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW32_RS20830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW32_RS20835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW32_RS20840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW32_RS20865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW32_RS20890	COG4970	Tfp pilus assembly protein FimT
EXW32_RS20900	COG1459	type II secretion system
EXW32_RS20905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW32_RS20960	COG0646	methionine synthase
EXW32_RS20960	COG1410	methionine synthase
EXW32_RS20965	COG0646	methionine synthase
EXW32_RS20965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW32_RS20970	COG0626	cystathionine gamma-synthase activity
EXW32_RS20975	COG0626	cystathionine gamma-synthase activity
EXW32_RS20995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS21005	COG1940	carbohydrate kinase activity
EXW32_RS21010	COG4483	Protein conserved in bacteria
EXW32_RS21015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW32_RS21020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW32_RS21025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW32_RS21030	COG0704	Plays a role in the regulation of phosphate uptake
EXW32_RS21040	COG0581	inorganic phosphate transmembrane transporter activity
EXW32_RS21045	COG0573	inorganic phosphate transmembrane transporter activity
EXW32_RS21050	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW32_RS21055	COG0768	penicillin binding
EXW32_RS21060	COG0477	Major facilitator Superfamily
EXW32_RS21065	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW32_RS21085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW32_RS21090	COG0735	belongs to the Fur family
EXW32_RS21095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW32_RS21100	COG1121	(ABC) transporter
EXW32_RS21105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS21115	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW32_RS21130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW32_RS21135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW32_RS21140	COG2384	SAM-dependent methyltransferase
EXW32_RS21145	COG2010	Cytochrome c
EXW32_RS21150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW32_RS21155	COG0358	DNA primase activity
EXW32_RS21165	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW32_RS21170	COG0517	IMP dehydrogenase activity
EXW32_RS21175	COG1381	Involved in DNA repair and RecF pathway recombination
EXW32_RS21185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW32_RS21190	COG0295	cytidine deaminase activity
EXW32_RS21195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW32_RS21200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW32_RS21205	COG1480	7TM receptor with intracellular HD hydrolase
EXW32_RS21210	COG1702	phosphate starvation-inducible protein PhoH
EXW32_RS21225	COG1610	YqeY-like protein
EXW32_RS21230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW32_RS21235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW32_RS21240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW32_RS21250	COG0484	heat shock protein binding
EXW32_RS21255	COG0443	Heat shock 70 kDa protein
EXW32_RS21265	COG1420	regulation of RNA biosynthetic process
EXW32_RS21270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW32_RS21275	COG1733	regulation of RNA biosynthetic process
EXW32_RS21280	COG0481	GTPase activity
EXW32_RS21290	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW32_RS21295	COG0268	Binds directly to 16S ribosomal RNA
EXW32_RS21300	COG1466	dna polymerase III delta subunit
EXW32_RS21310	COG2333	competence protein COMEC
EXW32_RS21310	COG0658	competence protein
EXW32_RS21315	COG2131	deaminase
EXW32_RS21320	COG1555	photosystem II stabilization
EXW32_RS21320	COG1596	polysaccharide export
EXW32_RS21325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW32_RS21330	COG2226	methyltransferase
EXW32_RS21335	COG0799	negative regulation of ribosome biogenesis
EXW32_RS21340	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW32_RS21345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW32_RS21350	COG1534	Rna-binding protein
EXW32_RS21355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW32_RS21360	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW32_RS21365	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW32_RS21375	COG0688	phosphatidylethanolamine metabolic process
EXW32_RS21385	COG1595	DNA-templated transcription, initiation
EXW32_RS21390	COG2357	RelA SpoT domain protein
EXW32_RS21400	COG1785	Belongs to the alkaline phosphatase family
EXW32_RS21410	COG2267	carboxylic ester hydrolase activity
EXW32_RS21445	COG1404	Belongs to the peptidase S8 family
EXW32_RS21450	COG3186	Phenylalanine-4-hydroxylase
EXW32_RS21455	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW32_RS21460	COG2514	catechol 2,3-dioxygenase activity
EXW32_RS21465	COG2259	Doxx family
EXW32_RS21505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS21515	COG1012	belongs to the aldehyde dehydrogenase family
EXW32_RS21515	COG1454	alcohol dehydrogenase
EXW32_RS21520	COG0626	cystathionine gamma-synthase activity
EXW32_RS21525	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW32_RS21530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW32_RS21535	COG2226	methyltransferase
EXW32_RS21550	COG0768	penicillin binding
EXW32_RS21555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW32_RS21560	COG0572	uridine kinase
EXW32_RS21565	COG0826	peptidase U32
EXW32_RS21570	COG0826	peptidase U32
EXW32_RS21575	COG4122	O-methyltransferase activity
EXW32_RS21580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW32_RS21590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW32_RS21595	COG4472	Bacterial protein of unknown function (DUF965)
EXW32_RS21600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW32_RS21610	COG0628	permease
EXW32_RS21630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW32_RS21640	COG0482	sulfurtransferase activity
EXW32_RS21645	COG1104	cysteine desulfurase activity
EXW32_RS21650	COG1959	2 iron, 2 sulfur cluster binding
EXW32_RS21655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW32_RS21665	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW32_RS21670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW32_RS21685	COG1490	D-aminoacyl-tRNA deacylase activity
EXW32_RS21690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW32_RS21695	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW32_RS21700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW32_RS21700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW32_RS21705	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW32_RS21710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW32_RS21710	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW32_RS21720	COG2244	polysaccharide biosynthetic process
EXW32_RS21725	COG2323	membrane
EXW32_RS21735	COG1862	Preprotein translocase
EXW32_RS21740	COG0343	queuine tRNA-ribosyltransferase activity
EXW32_RS21745	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW32_RS21755	COG2255	four-way junction helicase activity
EXW32_RS21760	COG0632	four-way junction helicase activity
EXW32_RS21765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW32_RS21790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW32_RS21795	COG0157	Belongs to the NadC ModD family
EXW32_RS21800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW32_RS21805	COG1104	cysteine desulfurase activity
EXW32_RS21810	COG1827	regulation of RNA biosynthetic process
EXW32_RS21815	COG2258	MOSC domain
EXW32_RS21820	COG0077	Prephenate dehydratase
EXW32_RS21825	COG0577	efflux transmembrane transporter activity
EXW32_RS21830	COG0577	efflux transmembrane transporter activity
EXW32_RS21835	COG1136	(ABC) transporter
EXW32_RS21840	COG5002	protein histidine kinase activity
EXW32_RS21845	COG0745	RESPONSE REGULATOR receiver
EXW32_RS21850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW32_RS21855	COG3290	protein histidine kinase activity
EXW32_RS21865	COG2868	ribosomal protein
EXW32_RS21875	COG1530	ribonuclease E activity
EXW32_RS21880	COG1994	Peptidase M50
EXW32_RS21885	COG0739	heme binding
EXW32_RS21890	COG2894	cell division
EXW32_RS21895	COG0850	regulation of cytokinetic process
EXW32_RS21910	COG1077	Cell shape determining protein MreB Mrl
EXW32_RS21945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS21960	COG1668	transmembrane transport
EXW32_RS21965	COG4152	abc transporter atp-binding protein
EXW32_RS22010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW32_RS22015	COG2226	methyltransferase
EXW32_RS22025	COG2003	Belongs to the UPF0758 family
EXW32_RS22030	COG0424	maF-like protein
EXW32_RS22040	COG0285	dihydrofolate synthase activity
EXW32_RS22055	COG1388	LysM domain
EXW32_RS22060	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW32_RS22065	COG0113	porphobilinogen synthase activity
EXW32_RS22070	COG1587	Uroporphyrinogen-III synthase
EXW32_RS22075	COG0181	hydroxymethylbilane synthase activity
EXW32_RS22080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW32_RS22085	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW32_RS22090	COG1846	Transcriptional regulator
EXW32_RS22095	COG1764	response to oxidative stress
EXW32_RS22100	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW32_RS22110	COG1067	ATP-dependent peptidase activity
EXW32_RS22110	COG0470	DNA polymerase III
EXW32_RS22120	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW32_RS22150	COG0622	Phosphoesterase
EXW32_RS22160	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW32_RS22165	COG5401	PFAM Sporulation and spore germination
EXW32_RS22175	COG0477	Major facilitator Superfamily
EXW32_RS22180	COG2197	response regulator
EXW32_RS22185	COG2233	PERMEase
EXW32_RS22190	COG0402	S-adenosylhomocysteine deaminase activity
EXW32_RS22195	COG1983	PspC domain protein
EXW32_RS22200	COG1396	sequence-specific DNA binding
EXW32_RS22205	COG0697	spore germination
EXW32_RS22215	COG1959	2 iron, 2 sulfur cluster binding
EXW32_RS22220	COG1668	transmembrane transport
EXW32_RS22225	COG4152	abc transporter atp-binding protein
EXW32_RS22230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW32_RS22235	COG1360	Flagellar Motor Protein
EXW32_RS22240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW32_RS22245	COG1876	peptidase activity
EXW32_RS22250	COG0824	Thioesterase
EXW32_RS22255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW32_RS22260	COG1053	succinate dehydrogenase
EXW32_RS22265	COG2009	succinate dehydrogenase
EXW32_RS22270	COG1719	4-vinyl reductase, 4VR
EXW32_RS22275	COG0322	excinuclease ABC activity
EXW32_RS22280	COG3118	belongs to the thioredoxin family
EXW32_RS22285	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW32_RS22290	COG2086	electron transfer activity
EXW32_RS22295	COG1024	Enoyl-CoA hydratase
EXW32_RS22300	COG1309	transcriptional regulator
EXW32_RS22305	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS22330	COG2318	DinB family
EXW32_RS22360	COG1131	(ABC) transporter
EXW32_RS22365	COG2205	protein histidine kinase activity
EXW32_RS22370	COG0745	RESPONSE REGULATOR receiver
EXW32_RS22380	COG4895	conserved protein (DUF2196)
EXW32_RS22385	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW32_RS22395	COG4509	Sortase family
EXW32_RS22400	COG1120	ATPase activity
EXW32_RS22415	COG5386	Cell surface protein
EXW32_RS22425	COG5386	Cell surface protein
EXW32_RS22430	COG1114	Component of the transport system for branched-chain amino acids
EXW32_RS22440	COG1193	negative regulation of DNA recombination
EXW32_RS22445	COG1796	DNA polymerase
EXW32_RS22445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW32_RS22450	COG1286	toxin biosynthetic process
EXW32_RS22455	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW32_RS22460	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW32_RS22485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW32_RS22490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW32_RS22500	COG1418	mRNA catabolic process
EXW32_RS22530	COG2814	Major facilitator Superfamily
EXW32_RS22535	COG1566	PFAM secretion protein HlyD family protein
EXW32_RS22540	COG1309	transcriptional regulator
EXW32_RS22545	COG1363	Peptidase, m42
EXW32_RS22555	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW32_RS22570	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW32_RS22580	COG1484	DNA-dependent DNA replication
EXW32_RS22585	COG3611	Membrane attachment protein
EXW32_RS22590	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW32_RS22595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW32_RS22600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW32_RS22605	COG0237	dephospho-CoA kinase activity
EXW32_RS22610	COG1971	Probably functions as a manganese efflux pump
EXW32_RS22620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW32_RS22620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW32_RS22625	COG5002	protein histidine kinase activity
EXW32_RS22630	COG0745	RESPONSE REGULATOR receiver
EXW32_RS22645	COG0039	L-malate dehydrogenase activity
EXW32_RS22650	COG0538	isocitrate dehydrogenase activity
EXW32_RS22655	COG0372	Belongs to the citrate synthase family
EXW32_RS22665	COG0628	permease
EXW32_RS22670	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW32_RS22680	COG0205	6-phosphofructokinase activity
EXW32_RS22690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW32_RS22695	COG1725	Transcriptional regulator
EXW32_RS22700	COG0281	malic enzyme
EXW32_RS22705	COG0587	DNA-directed DNA polymerase activity
EXW32_RS22720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW32_RS22735	COG4109	DRTGG domain
EXW32_RS22750	COG0006	proline dipeptidase activity
EXW32_RS22780	COG0662	Cupin 2, conserved barrel domain protein
EXW32_RS22790	COG1476	TRANSCRIPTIONal
EXW32_RS22805	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS22810	COG0589	response to stress
EXW32_RS22840	COG0137	argininosuccinate synthase activity
EXW32_RS22855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS22875	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW32_RS22880	COG0827	DNA restriction-modification system
EXW32_RS22885	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW32_RS22890	COG3874	Sporulation protein YtfJ
EXW32_RS22905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW32_RS22915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW32_RS22930	COG1104	cysteine desulfurase activity
EXW32_RS22935	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW32_RS22950	COG1309	transcriptional regulator
EXW32_RS22955	COG1956	GAF domain-containing protein
EXW32_RS22960	COG0626	cystathionine gamma-synthase activity
EXW32_RS22965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW32_RS22990	COG1595	DNA-templated transcription, initiation
EXW32_RS23000	COG0110	maltose O-acetyltransferase activity
EXW32_RS23010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW32_RS23015	COG0454	-acetyltransferase
EXW32_RS23020	COG0517	IMP dehydrogenase activity
EXW32_RS23025	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW32_RS23040	COG0745	RESPONSE REGULATOR receiver
EXW32_RS23045	COG5002	protein histidine kinase activity
EXW32_RS23050	COG0666	response to abiotic stimulus
EXW32_RS23060	COG1970	mechanosensitive ion channel activity
EXW32_RS23085	COG1609	Transcriptional regulator
EXW32_RS23100	COG4851	CamS sex pheromone cAM373 precursor
EXW32_RS23105	COG3118	belongs to the thioredoxin family
EXW32_RS23115	COG2309	aminopeptidase activity
EXW32_RS23145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW32_RS23155	COG1674	ftsk spoiiie
EXW32_RS23170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW32_RS23175	COG4848	Belongs to the UPF0354 family
EXW32_RS23180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS23185	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW32_RS23190	COG1363	Peptidase, m42
EXW32_RS23200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS23205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW32_RS23215	COG0510	thiamine kinase activity
EXW32_RS23220	COG1523	belongs to the glycosyl hydrolase 13 family
EXW32_RS23230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW32_RS23235	COG1349	DNA-binding transcription factor activity
EXW32_RS23240	COG1187	pseudouridine synthase activity
EXW32_RS23245	COG2244	polysaccharide biosynthetic process
EXW32_RS23250	COG2081	HI0933 family
EXW32_RS23255	COG2814	Major facilitator Superfamily
EXW32_RS23265	COG3832	glyoxalase III activity
EXW32_RS23285	COG1329	Transcriptional regulator
EXW32_RS23310	COG0314	molybdopterin synthase activity
EXW32_RS23315	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW32_RS23320	COG0303	'Molybdopterin
EXW32_RS23325	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW32_RS23330	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW32_RS23335	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW32_RS23355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW32_RS23365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW32_RS23405	COG0495	leucyl-tRNA aminoacylation
EXW32_RS23410	COG2814	Major facilitator Superfamily
EXW32_RS23415	COG0475	glutathione-regulated potassium exporter activity
EXW32_RS23420	COG0490	domain, Protein
EXW32_RS23425	COG0582	viral genome integration into host DNA
EXW32_RS23435	COG1136	(ABC) transporter
EXW32_RS23450	COG1242	4 iron, 4 sulfur cluster binding
EXW32_RS23455	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW32_RS23460	COG1131	(ABC) transporter
EXW32_RS23485	COG2267	carboxylic ester hydrolase activity
EXW32_RS23490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW32_RS23495	COG0671	phosphoesterase, PA-phosphatase related
EXW32_RS23500	COG0438	transferase activity, transferring glycosyl groups
EXW32_RS23515	COG0746	molybdenum cofactor guanylyltransferase activity
EXW32_RS23535	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW32_RS23540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW32_RS23575	COG5002	protein histidine kinase activity
EXW32_RS23580	COG3852	Histidine kinase
EXW32_RS23585	COG0753	catalase activity
EXW32_RS23590	COG2267	carboxylic ester hydrolase activity
EXW32_RS23600	COG1368	sulfuric ester hydrolase activity
EXW32_RS23610	COG4895	conserved protein (DUF2196)
EXW32_RS23625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW32_RS23630	COG1116	anion transmembrane transporter activity
EXW32_RS23635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW32_RS23660	COG0494	nUDIX hydrolase
EXW32_RS23695	COG2076	Multidrug Resistance protein
EXW32_RS23700	COG2076	Multidrug Resistance protein
EXW32_RS23705	COG0789	Transcriptional regulator
EXW32_RS23710	COG1854	S-ribosylhomocysteine lyase activity
EXW32_RS23720	COG0288	reversible hydration of carbon dioxide
EXW32_RS23725	COG1271	oxidase subunit
EXW32_RS23730	COG1294	oxidase, subunit
EXW32_RS23750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS23775	COG1842	Phage shock protein A
EXW32_RS23800	COG3859	Proton-coupled thiamine transporter YuaJ
EXW32_RS23805	COG5002	protein histidine kinase activity
EXW32_RS23810	COG0745	RESPONSE REGULATOR receiver
EXW32_RS23835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW32_RS23840	COG1597	lipid kinase activity
EXW32_RS23865	COG1136	(ABC) transporter
EXW32_RS23895	COG5002	protein histidine kinase activity
EXW32_RS23905	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS23920	COG0577	efflux transmembrane transporter activity
EXW32_RS23925	COG1136	(ABC) transporter
EXW32_RS23930	COG2207	Transcriptional regulator
EXW32_RS23930	COG3708	Transcriptional regulator
EXW32_RS23940	COG1131	(ABC) transporter
EXW32_RS23950	COG5658	integral membrane protein
EXW32_RS23955	COG0640	Transcriptional regulator
EXW32_RS23960	COG0745	RESPONSE REGULATOR receiver
EXW32_RS23965	COG2205	protein histidine kinase activity
EXW32_RS23970	COG0577	efflux transmembrane transporter activity
EXW32_RS23975	COG0577	efflux transmembrane transporter activity
EXW32_RS23980	COG1136	(ABC) transporter
EXW32_RS23985	COG0577	efflux transmembrane transporter activity
EXW32_RS24000	COG2188	Transcriptional regulator
EXW32_RS24020	COG3964	amidohydrolase
EXW32_RS24040	COG4948	Mandelate Racemase Muconate Lactonizing
EXW32_RS24045	COG0318	PFAM AMP-dependent synthetase and ligase
EXW32_RS24055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW32_RS24065	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW32_RS24070	COG1169	isochorismate synthase
EXW32_RS24075	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW32_RS24080	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW32_RS24085	COG1278	Cold shock
EXW32_RS24095	COG0789	Transcriptional regulator
EXW32_RS24105	COG0058	SHG alpha-glucan phosphorylase activity
EXW32_RS24115	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW32_RS24120	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW32_RS24125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW32_RS24150	COG1595	DNA-templated transcription, initiation
EXW32_RS24285	COG1285	pathogenesis
EXW32_RS24290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW32_RS24300	COG0166	Belongs to the GPI family
EXW32_RS24305	COG2155	Conserved Protein
EXW32_RS24310	COG1098	S1 RNA binding domain
EXW32_RS24315	COG0436	Aminotransferase
EXW32_RS24320	COG1522	sequence-specific DNA binding
EXW32_RS24325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW32_RS24330	COG2267	carboxylic ester hydrolase activity
EXW32_RS24340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW32_RS24360	COG5018	Exonuclease
EXW32_RS24365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW32_RS24385	COG2050	protein possibly involved in aromatic compounds catabolism
EXW32_RS24395	COG1268	BioY protein
EXW32_RS24405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW32_RS24410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW32_RS24420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW32_RS24425	COG3584	3D domain protein
EXW32_RS24440	COG1252	NADH dehydrogenase
EXW32_RS24445	COG0492	ferredoxin-NADP+ reductase activity
EXW32_RS24450	COG3708	Transcriptional regulator
EXW32_RS24465	COG1683	Conserved Protein
EXW32_RS24485	COG0316	Belongs to the HesB IscA family
EXW32_RS24490	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW32_RS24495	COG4844	belongs to the
EXW32_RS24500	COG1252	NADH dehydrogenase
EXW32_RS24510	COG0390	transport system, permease component
EXW32_RS24515	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW32_RS24545	COG4837	Protein of unknown function (DUF1462)
EXW32_RS24550	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW32_RS24560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW32_RS24565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW32_RS24580	COG0577	efflux transmembrane transporter activity
EXW32_RS24580	COG1136	(ABC) transporter
EXW32_RS24585	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW32_RS24595	COG0647	UMP catabolic process
EXW32_RS24605	COG2445	Protein of unknown function DUF86
EXW32_RS24610	COG1494	fructose-1,6-bisphosphatase
EXW32_RS24625	COG4470	Protein conserved in bacteria
EXW32_RS24635	COG0789	Transcriptional regulator
EXW32_RS24640	COG4377	Putative membrane peptidase family (DUF2324)
EXW32_RS24660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW32_RS24665	COG0739	heme binding
EXW32_RS24675	COG3377	Domain of unknown function (DUF1805)
EXW32_RS24680	COG0737	Belongs to the 5'-nucleotidase family
EXW32_RS24685	COG1695	Transcriptional regulator
EXW32_RS24695	COG0719	Fe-S assembly protein
EXW32_RS24700	COG0822	iron-sulfur transferase activity
EXW32_RS24705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW32_RS24710	COG0719	Fe-S assembly protein
EXW32_RS24715	COG0396	ATPase activity
EXW32_RS24720	COG1464	Belongs to the NlpA lipoprotein family
EXW32_RS24725	COG1464	Belongs to the NlpA lipoprotein family
EXW32_RS24730	COG2011	ABC-type metal ion transport system permease component
EXW32_RS24735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW32_RS24745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW32_RS24750	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW32_RS24755	COG0509	glycine decarboxylation via glycine cleavage system
EXW32_RS24760	COG1393	Belongs to the ArsC family
EXW32_RS24795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS24800	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS24805	COG0183	Belongs to the thiolase family
EXW32_RS24810	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW32_RS24810	COG1024	Enoyl-CoA hydratase
EXW32_RS24820	COG1686	Belongs to the peptidase S11 family
EXW32_RS24825	COG0506	proline dehydrogenase activity
EXW32_RS24835	COG0011	TIGRFAM Protein of
EXW32_RS24840	COG0840	transmembrane signaling receptor activity
EXW32_RS24855	COG2814	Major facilitator Superfamily
EXW32_RS24860	COG0531	amino acid
EXW32_RS24885	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW32_RS24945	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS24955	COG1376	ErfK ybiS ycfS ynhG family protein
EXW32_RS24960	COG0745	RESPONSE REGULATOR receiver
EXW32_RS24965	COG5002	protein histidine kinase activity
EXW32_RS24975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW32_RS24985	COG0840	transmembrane signaling receptor activity
EXW32_RS24990	COG0840	transmembrane signaling receptor activity
EXW32_RS24995	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW32_RS25000	COG3227	Zinc metalloprotease (Elastase)
EXW32_RS25005	COG1741	Belongs to the pirin family
EXW32_RS25020	COG0586	Pfam SNARE associated Golgi protein
EXW32_RS25025	COG0475	glutathione-regulated potassium exporter activity
EXW32_RS25030	COG0490	domain, Protein
EXW32_RS25035	COG1115	amino acid carrier protein
EXW32_RS25040	COG0783	Belongs to the Dps family
EXW32_RS25050	COG2318	DinB family
EXW32_RS25055	COG1611	Belongs to the LOG family
EXW32_RS25065	COG1528	Iron-storage protein
EXW32_RS25070	COG2311	Membrane
EXW32_RS25075	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS25080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS25085	COG1115	amino acid carrier protein
EXW32_RS25090	COG1115	amino acid carrier protein
EXW32_RS25095	COG2910	NAD(P)H-binding
EXW32_RS25105	COG0656	L-ascorbic acid biosynthetic process
EXW32_RS25110	COG2814	Major facilitator Superfamily
EXW32_RS25115	COG1733	regulation of RNA biosynthetic process
EXW32_RS25125	COG1252	NADH dehydrogenase
EXW32_RS25145	COG3290	protein histidine kinase activity
EXW32_RS25145	COG0840	transmembrane signaling receptor activity
EXW32_RS25155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW32_RS25175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW32_RS25190	COG4224	UPF0291 protein
EXW32_RS25195	COG1335	isochorismatase
EXW32_RS25200	COG1522	sequence-specific DNA binding
EXW32_RS25210	COG1522	sequence-specific DNA binding
EXW32_RS25215	COG0288	reversible hydration of carbon dioxide
EXW32_RS25220	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW32_RS25225	COG2233	PERMEase
EXW32_RS25270	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW32_RS25275	COG0557	exoribonuclease II activity
EXW32_RS25280	COG1647	Serine aminopeptidase, S33
EXW32_RS25285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW32_RS25290	COG1346	cytolysis
EXW32_RS25305	COG0148	phosphopyruvate hydratase activity
EXW32_RS25315	COG0149	triose-phosphate isomerase activity
EXW32_RS25320	COG0126	phosphoglycerate kinase activity
EXW32_RS25325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW32_RS25340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW32_RS25375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW32_RS25390	COG2323	membrane
EXW32_RS25400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW32_RS25405	COG1481	regulation of sporulation
EXW32_RS25410	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW32_RS25415	COG1660	Displays ATPase and GTPase activities
EXW32_RS25420	COG1051	belongs to the nudix hydrolase family
EXW32_RS25430	COG0492	ferredoxin-NADP+ reductase activity
EXW32_RS25435	COG0457	Tetratricopeptide repeat
EXW32_RS25440	COG0110	maltose O-acetyltransferase activity
EXW32_RS25445	COG0546	phosphoglycolate phosphatase activity
EXW32_RS25450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW32_RS25455	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW32_RS25460	COG1950	PFAM Membrane protein of
EXW32_RS25465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW32_RS25485	COG0789	Transcriptional regulator
EXW32_RS25520	COG0583	DNA-binding transcription factor activity
EXW32_RS25525	COG0789	Transcriptional regulator
EXW32_RS25530	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW32_RS25535	COG0488	(ABC) transporter
EXW32_RS25545	COG1132	(ABC) transporter
EXW32_RS25550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW32_RS25555	COG0793	Belongs to the peptidase S41A family
EXW32_RS25555	COG3409	Peptidoglycan-binding domain 1 protein
EXW32_RS25560	COG2177	Part of the ABC transporter FtsEX involved in
EXW32_RS25565	COG2884	Cell division ATP-binding protein ftsE
EXW32_RS25590	COG1131	(ABC) transporter
EXW32_RS25625	COG1278	Cold shock
EXW32_RS25630	COG1040	competence protein
EXW32_RS25635	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW32_RS25640	COG1388	LysM domain
EXW32_RS25640	COG0791	NLP P60 protein
EXW32_RS25645	COG1733	regulation of RNA biosynthetic process
EXW32_RS25650	COG1307	EDD domain protein, DegV family
EXW32_RS25655	COG1739	Uncharacterized protein family UPF0029
EXW32_RS25660	COG1316	TRANSCRIPTIONal
EXW32_RS25665	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW32_RS25670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW32_RS25675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW32_RS25685	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW32_RS25685	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW32_RS25705	COG1486	melibiose metabolic process
EXW32_RS25710	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW32_RS25715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW32_RS25735	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW32_RS25745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW32_RS25750	COG1301	dicarboxylic acid transport
EXW32_RS25765	COG1511	domain protein
EXW32_RS25770	COG0583	DNA-binding transcription factor activity
EXW32_RS25795	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW32_RS25805	COG2801	Transposase and inactivated derivatives
EXW32_RS25815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW32_RS25825	COG1271	oxidase subunit
EXW32_RS25830	COG1294	oxidase, subunit
EXW32_RS25835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW32_RS25840	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW32_RS25845	COG1620	l-lactate permease
EXW32_RS25855	COG2389	metal-binding protein
EXW32_RS25865	COG1368	sulfuric ester hydrolase activity
EXW32_RS25875	COG1388	LysM domain
EXW32_RS25875	COG0791	NLP P60 protein
EXW32_RS25880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW32_RS25890	COG1215	transferase activity, transferring glycosyl groups
EXW32_RS25895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW32_RS25900	COG1388	LysM domain
EXW32_RS25900	COG3584	3D domain protein
EXW32_RS25925	COG4715	Zinc finger, swim domain protein
EXW32_RS25930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW32_RS25970	COG0577	efflux transmembrane transporter activity
EXW32_RS25975	COG1136	(ABC) transporter
EXW32_RS26000	COG3850	Histidine kinase
EXW32_RS26000	COG5002	protein histidine kinase activity
EXW32_RS26005	COG0745	RESPONSE REGULATOR receiver
EXW32_RS26010	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW32_RS26025	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW32_RS26040	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW32_RS26075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW32_RS26080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW32_RS26085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW32_RS26090	COG4464	protein tyrosine phosphatase activity
EXW32_RS26095	COG0489	protein tyrosine kinase activity
EXW32_RS26100	COG3944	biosynthesis protein
EXW32_RS26105	COG0489	protein tyrosine kinase activity
EXW32_RS26120	COG1609	Transcriptional regulator
EXW32_RS26130	COG0739	heme binding
EXW32_RS26145	COG3279	Response regulator of the LytR AlgR family
EXW32_RS26150	COG2385	sporulation resulting in formation of a cellular spore
EXW32_RS26165	COG4836	Membrane
EXW32_RS26170	COG1007	ATP synthesis coupled electron transport
EXW32_RS26175	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW32_RS26180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW32_RS26185	COG0713	ATP synthesis coupled electron transport
EXW32_RS26190	COG0839	Belongs to the complex I subunit 6 family
EXW32_RS26200	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW32_RS26205	COG0649	NAD binding
EXW32_RS26210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW32_RS26215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW32_RS26220	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW32_RS26225	COG3300	MHYT domain
EXW32_RS26225	COG5001	Diguanylate cyclase
EXW32_RS26240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW32_RS26245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW32_RS26260	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW32_RS26265	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW32_RS26275	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW32_RS26310	COG0698	ribose 5-phosphate isomerase
EXW32_RS26320	COG2190	(PTS) system
EXW32_RS26325	COG2259	Doxx family
EXW32_RS26330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW32_RS26340	COG1971	Probably functions as a manganese efflux pump
EXW32_RS26345	COG0009	L-threonylcarbamoyladenylate synthase
EXW32_RS26360	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW32_RS26365	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW32_RS26370	COG1435	thymidine kinase activity
EXW32_RS26380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW32_RS26385	COG1494	fructose-1,6-bisphosphatase
EXW32_RS26405	COG4821	SIS domain
EXW32_RS26410	COG0504	CTP synthase activity
EXW32_RS26415	COG3343	RNA polymerase activity
EXW32_RS26425	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS26430	COG1960	acyl-CoA dehydrogenase activity
EXW32_RS26435	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW32_RS26440	COG0183	Belongs to the thiolase family
EXW32_RS26445	COG2181	nitrate reductase activity
EXW32_RS26445	COG0247	lactate metabolic process
EXW32_RS26450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW32_RS26455	COG4294	response to UV
EXW32_RS26460	COG5001	Diguanylate cyclase
EXW32_RS26460	COG3300	MHYT domain
EXW32_RS26475	COG3227	Zinc metalloprotease (Elastase)
EXW32_RS26480	COG2197	response regulator
EXW32_RS26485	COG4585	Histidine kinase
EXW32_RS26490	COG0842	Transport permease protein
EXW32_RS26495	COG1131	(ABC) transporter
EXW32_RS26500	COG0024	Methionine aminopeptidase
EXW32_RS26505	COG2234	aminopeptidase activity
EXW32_RS26520	COG4506	Protein conserved in bacteria
EXW32_RS26525	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW32_RS26540	COG0010	Belongs to the arginase family
EXW32_RS26545	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW32_RS26550	COG2814	Major facilitator Superfamily
EXW32_RS26555	COG0789	Transcriptional regulator
EXW32_RS26560	COG0584	glycerophosphoryl diester phosphodiesterase
EXW32_RS26565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW32_RS26575	COG1994	Peptidase M50
EXW32_RS26585	COG1078	dGTPase activity
EXW32_RS26590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW32_RS26595	COG1120	ATPase activity
EXW32_RS26600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS26605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW32_RS26610	COG4844	belongs to the
EXW32_RS26625	COG0280	phosphate acetyltransferase
EXW32_RS26630	COG3253	May function as heme-dependent peroxidase
EXW32_RS26640	COG3773	Cell wall hydrolase
EXW32_RS26650	COG2363	Small membrane protein
EXW32_RS26665	COG2233	PERMEase
EXW32_RS26670	COG0561	phosphatase activity
EXW32_RS26675	COG2814	Major facilitator Superfamily
EXW32_RS26680	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW32_RS26685	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW32_RS26690	COG1131	(ABC) transporter
EXW32_RS26695	COG2755	lipolytic protein G-D-S-L family
EXW32_RS26700	COG1609	Transcriptional regulator
EXW32_RS26710	COG0460	homoserine dehydrogenase
EXW32_RS26715	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW32_RS26720	COG2873	o-acetylhomoserine
EXW32_RS26730	COG1011	Hydrolase
EXW32_RS26735	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW32_RS26745	COG2197	response regulator
EXW32_RS26750	COG4585	Histidine kinase
EXW32_RS26750	COG2203	Gaf domain
EXW32_RS26755	COG0351	phosphomethylpyrimidine kinase
EXW32_RS26760	COG3706	GGDEF domain
EXW32_RS26765	COG2879	small protein
EXW32_RS26770	COG1966	Carbon starvation protein
EXW32_RS26775	COG3279	Response regulator of the LytR AlgR family
EXW32_RS26780	COG0477	Major facilitator Superfamily
EXW32_RS26805	COG0840	transmembrane signaling receptor activity
EXW32_RS26815	COG1607	acyl-coa hydrolase
EXW32_RS26820	COG1216	Glycosyl transferase, family 2
EXW32_RS26830	COG1216	Glycosyl transferase, family 2
EXW32_RS26840	COG4485	Bacterial membrane protein, YfhO
EXW32_RS26845	COG0463	Glycosyl transferase, family 2
EXW32_RS26855	COG1309	transcriptional regulator
EXW32_RS26860	COG0488	(ABC) transporter
EXW32_RS26865	COG1309	transcriptional regulator
EXW32_RS26870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW32_RS26875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW32_RS26875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW32_RS26880	COG0628	permease
EXW32_RS26890	COG1380	Effector of murein hydrolase LrgA
EXW32_RS26895	COG3279	Response regulator of the LytR AlgR family
EXW32_RS26900	COG3275	phosphorelay sensor kinase activity
EXW32_RS26905	COG2814	Major facilitator Superfamily
EXW32_RS26910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW32_RS26915	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW32_RS26920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW32_RS26970	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW32_RS26975	COG1272	protein, Hemolysin III
EXW32_RS27000	COG1164	Oligoendopeptidase f
EXW32_RS27010	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW32_RS27020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW32_RS27025	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW32_RS27030	COG4853	Protein conserved in bacteria
EXW32_RS27040	COG5002	protein histidine kinase activity
EXW32_RS27045	COG0745	RESPONSE REGULATOR receiver
EXW32_RS27075	COG0305	Participates in initiation and elongation during chromosome replication
EXW32_RS27080	COG0359	binds to the 23S rRNA
EXW32_RS27085	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW32_RS27090	COG4241	membrane
EXW32_RS27100	COG0629	single-stranded DNA binding
EXW32_RS27105	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW32_RS27110	COG0012	GTP binding
EXW32_RS27115	COG4481	Protein conserved in bacteria
EXW32_RS27120	COG0668	transmembrane transport
EXW32_RS27130	COG1475	DNA binding
EXW32_RS27135	COG1192	Involved in chromosome partitioning
EXW32_RS27140	COG1475	DNA binding
EXW32_RS27145	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW32_RS27150	COG0445	tRNA wobble uridine modification
EXW32_RS27155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW32_RS27160	COG1847	R3H domain protein
EXW32_RS27165	COG0706	membrane insertase activity
EXW32_RS27170	COG0594	ribonuclease P activity
EXW32_RS27175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW32_RS27185	COG1876	peptidase activity
EXW32_RS27295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW32_RS27340	COG1733	regulation of RNA biosynthetic process
EXW32_RS27350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EXW32_RS27360	COG2918	glutathione biosynthetic process
EXW32_RS27360	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW32_RS27370	COG0583	DNA-binding transcription factor activity
EXW32_RS27390	COG0083	homoserine kinase activity
EXW32_RS27405	COG1309	transcriptional regulator
EXW32_RS27410	COG2814	Major facilitator Superfamily
EXW32_RS27420	COG2508	Transcriptional regulator
EXW32_RS27420	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW32_RS27425	COG0686	Belongs to the AlaDH PNT family
EXW32_RS27490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW32_RS27525	COG0791	NLP P60 protein
EXW32_RS27525	COG3103	Sh3 type 3 domain protein
EXW32_RS27525	COG1388	LysM domain
EXW32_RS27570	COG1396	sequence-specific DNA binding
EXW32_RS27590	COG0840	transmembrane signaling receptor activity
EXW32_RS27595	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW32_RS27620	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW32_RS27625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW32_RS27630	COG0772	Belongs to the SEDS family
EXW32_RS27635	COG2239	Acts as a magnesium transporter
EXW32_RS27645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW32_RS27685	COG0024	Methionine aminopeptidase
EXW32_RS27730	COG4974	Belongs to the 'phage' integrase family
EXW32_RS27815	COG2357	RelA SpoT domain protein
EXW32_RS27820	COG2814	Major facilitator Superfamily
EXW32_RS27865	COG0833	amino acid
EXW32_RS27870	COG2040	homocysteine
EXW32_RS27890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW32_RS27900	COG0741	lytic transglycosylase activity
EXW32_RS27925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW32_RS27940	COG1819	glycosyl
EXW32_RS27960	COG0457	Tetratricopeptide repeat
EXW32_RS27970	COG1695	Transcriptional regulator
EXW32_RS28050	COG2140	Oxalate decarboxylase
EXW32_RS28125	COG0156	8-amino-7-oxononanoate synthase activity
EXW32_RS28140	COG1725	Transcriptional regulator
EXW32_RS28145	COG1131	(ABC) transporter
EXW32_RS28180	COG1329	Transcriptional regulator
EXW32_RS28200	COG3344	reverse transcriptase
EXW32_RS28250	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW32_RS28265	COG4176	ABC-type proline glycine betaine transport system permease component
EXW32_RS28270	COG4175	Glycine betaine
EXW32_RS28270	COG0517	IMP dehydrogenase activity
EXW32_RS28290	COG0697	spore germination
EXW32_RS28350	COG1073	alpha beta
EXW32_RS28355	COG0456	acetyltransferase
EXW32_RS28365	COG0457	Tetratricopeptide repeat
EXW32_RS28430	COG1396	sequence-specific DNA binding
EXW32_RS28580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW32_RS28625	COG0367	asparagine synthase
EXW32_RS28660	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW32_RS28680	COG0739	heme binding
EXW32_RS28755	COG0542	response to heat
EXW32_RS28835	COG3220	belongs to the UPF0276 family
EXW32_RS28840	COG1404	Belongs to the peptidase S8 family
EXW32_RS28850	COG1132	(ABC) transporter
EXW32_RS28865	COG2814	Major facilitator Superfamily
EXW32_RS28870	COG2234	aminopeptidase activity
EXW32_RS28880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW32_RS28895	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW32_RS28900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW32_RS28905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW32_RS28915	COG0456	acetyltransferase
EXW32_RS28950	COG1028	Short-chain dehydrogenase reductase Sdr
EXW32_RS29020	COG0673	inositol 2-dehydrogenase activity
EXW32_RS29025	COG0673	inositol 2-dehydrogenase activity
EXW32_RS29030	COG2169	Transcriptional regulator
EXW32_RS29055	COG1476	TRANSCRIPTIONal
EXW32_RS29250	COG0500	methyltransferase
EXW32_RS29285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW32_RS29305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW32_RS29315	COG1785	Belongs to the alkaline phosphatase family
EXW32_RS29375	COG3344	reverse transcriptase
EXW32_RS29405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW32_RS29420	COG2140	Oxalate decarboxylase
EXW32_RS29425	COG2311	Membrane
EXW32_RS29475	COG0583	DNA-binding transcription factor activity
EXW32_RS29545	COG0463	Glycosyl transferase, family 2
EXW32_RS29550	COG0463	Glycosyl transferase, family 2
EXW32_RS29555	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW32_RS29560	COG1086	Polysaccharide biosynthesis protein
EXW32_RS29565	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW32_RS29570	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW32_RS29575	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW32_RS29590	COG2089	acid synthase
EXW32_RS29595	COG4641	Protein conserved in bacteria
EXW32_RS29655	COG0745	RESPONSE REGULATOR receiver
EXW32_RS29660	COG2205	protein histidine kinase activity
EXW32_RS29670	COG1136	(ABC) transporter
EXW32_RS29675	COG0577	efflux transmembrane transporter activity
EXW32_RS29690	COG2002	toxin-antitoxin pair type II binding
EXW32_RS29700	COG1923	regulation of RNA biosynthetic process
EXW32_RS29725	COG2814	Major facilitator Superfamily
EXW32_RS29940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW32_RS29945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol