locus-tag	class	description
EXW38_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW38_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW38_RS00015	COG2501	S4 domain
EXW38_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_RS00025	COG0187	DNA topoisomerase II activity
EXW38_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW38_RS00065	COG0516	GMP reductase activity
EXW38_RS00065	COG0517	IMP dehydrogenase activity
EXW38_RS00070	COG1686	Belongs to the peptidase S11 family
EXW38_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW38_RS00100	COG1428	Deoxynucleoside kinase
EXW38_RS00105	COG1428	Deoxynucleoside kinase
EXW38_RS00110	COG1335	isochorismatase
EXW38_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW38_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW38_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW38_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW38_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW38_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW38_RS00190	COG0470	DNA polymerase III
EXW38_RS00195	COG1774	PSP1 C-terminal conserved region
EXW38_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW38_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW38_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW38_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW38_RS00230	COG0084	hydrolase, TatD family'
EXW38_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW38_RS00250	COG4466	Protein conserved in bacteria
EXW38_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW38_RS00270	COG0251	oxidation-reduction process
EXW38_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW38_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW38_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW38_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW38_RS00310	COG2244	polysaccharide biosynthetic process
EXW38_RS00315	COG3956	TIGRFAM MazG family protein
EXW38_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW38_RS00340	COG1098	S1 RNA binding domain
EXW38_RS00355	COG2208	phosphoserine phosphatase activity
EXW38_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW38_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW38_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW38_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW38_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW38_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW38_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW38_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW38_RS00420	COG1396	sequence-specific DNA binding
EXW38_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW38_RS00515	COG3880	PFAM UvrB UvrC protein
EXW38_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW38_RS00525	COG0542	response to heat
EXW38_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW38_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW38_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW38_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW38_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW38_RS00560	COG1045	serine acetyltransferase
EXW38_RS00565	COG0215	cysteine-tRNA ligase activity
EXW38_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW38_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW38_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW38_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW38_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW38_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW38_RS00610	COG0081	regulation of translation
EXW38_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW38_RS00620	COG0222	ribosome binding
EXW38_RS00625	COG2813	Specifically methylates the guanine in position
EXW38_RS00630	COG0085	RNA polymerase activity
EXW38_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW38_RS00640	COG1358	cellular component organization or biogenesis
EXW38_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW38_RS00650	COG0049	tRNA binding
EXW38_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW38_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW38_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW38_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW38_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW38_RS00680	COG0089	rRNA binding
EXW38_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW38_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW38_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW38_RS00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW38_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW38_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW38_RS00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW38_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW38_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW38_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW38_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW38_RS00760	COG1841	ribosomal large subunit assembly
EXW38_RS00765	COG0200	Binds to the 23S rRNA
EXW38_RS00770	COG0201	protein transport
EXW38_RS00775	COG0563	adenylate kinase activity
EXW38_RS00780	COG0024	Methionine aminopeptidase
EXW38_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW38_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW38_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW38_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW38_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW38_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW38_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS00855	COG0489	protein tyrosine kinase activity
EXW38_RS00865	COG2194	sulfuric ester hydrolase activity
EXW38_RS00870	COG0726	polysaccharide deacetylase
EXW38_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW38_RS00955	COG4856	YbbR-like protein
EXW38_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS01010	COG2011	ABC-type metal ion transport system permease component
EXW38_RS01020	COG1464	Belongs to the NlpA lipoprotein family
EXW38_RS01025	COG0604	alcohol dehydrogenase
EXW38_RS01035	COG0277	FAD linked oxidase domain protein
EXW38_RS01040	COG2271	Major facilitator Superfamily
EXW38_RS01050	COG2814	Major facilitator Superfamily
EXW38_RS01070	COG0601	transmembrane transport
EXW38_RS01075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_RS01080	COG0444	Belongs to the ABC transporter superfamily
EXW38_RS01085	COG4608	Belongs to the ABC transporter superfamily
EXW38_RS01090	COG4166	transmembrane transport
EXW38_RS01100	COG2207	Transcriptional regulator
EXW38_RS01115	COG4166	transmembrane transport
EXW38_RS01120	COG4166	transmembrane transport
EXW38_RS01125	COG0656	L-ascorbic acid biosynthetic process
EXW38_RS01130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_RS01140	COG4149	molybdate abc transporter
EXW38_RS01145	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW38_RS01150	COG1910	domain protein
EXW38_RS01165	COG0697	spore germination
EXW38_RS01180	COG0204	Acyl-transferase
EXW38_RS01190	COG1609	Transcriptional regulator
EXW38_RS01200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS01215	COG5298	Protein conserved in bacteria
EXW38_RS01235	COG0488	(ABC) transporter
EXW38_RS01245	COG0747	negative chemotaxis
EXW38_RS01250	COG0747	negative chemotaxis
EXW38_RS01255	COG0601	transmembrane transport
EXW38_RS01260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_RS01265	COG0444	Belongs to the ABC transporter superfamily
EXW38_RS01270	COG4608	Belongs to the ABC transporter superfamily
EXW38_RS01275	COG0561	phosphatase activity
EXW38_RS01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW38_RS01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_RS01320	COG0531	amino acid
EXW38_RS01325	COG2814	Major facilitator Superfamily
EXW38_RS01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW38_RS01345	COG4294	response to UV
EXW38_RS01350	COG0705	Rhomboid family
EXW38_RS01355	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW38_RS01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW38_RS01365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW38_RS01370	COG0864	Transcriptional regulator
EXW38_RS01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW38_RS01380	COG2183	response to ionizing radiation
EXW38_RS01480	COG0802	atpase or kinase
EXW38_RS01485	COG1214	PFAM Peptidase M22, glycoprotease
EXW38_RS01490	COG0456	acetyltransferase
EXW38_RS01500	COG0488	(ABC) transporter
EXW38_RS01505	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW38_RS01515	COG1266	CAAX protease self-immunity
EXW38_RS01520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW38_RS01525	COG0459	protein refolding
EXW38_RS01530	COG0519	Catalyzes the synthesis of GMP from XMP
EXW38_RS01530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW38_RS01535	COG2252	PERMEase
EXW38_RS01545	COG5002	protein histidine kinase activity
EXW38_RS01565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW38_RS01605	COG4187	Peptidase family M20/M25/M40
EXW38_RS01645	COG0697	spore germination
EXW38_RS01665	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW38_RS01670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW38_RS01675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW38_RS01685	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW38_RS01690	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW38_RS01695	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW38_RS01700	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW38_RS01705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW38_RS01710	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW38_RS01715	COG0138	bifunctional purine biosynthesis protein purh
EXW38_RS01720	COG0151	Belongs to the GarS family
EXW38_RS01740	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW38_RS01745	COG0210	DNA helicase
EXW38_RS01750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW38_RS01755	COG4851	CamS sex pheromone cAM373 precursor
EXW38_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS01770	COG1335	isochorismatase
EXW38_RS01780	COG2011	ABC-type metal ion transport system permease component
EXW38_RS01785	COG1464	Belongs to the NlpA lipoprotein family
EXW38_RS01795	COG0003	Pfam Anion-transporting ATPase
EXW38_RS01800	COG1846	Transcriptional regulator
EXW38_RS01805	COG4682	membrane
EXW38_RS01815	COG0154	amidase activity
EXW38_RS01820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW38_RS01825	COG1597	lipid kinase activity
EXW38_RS01840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS01855	COG2076	Multidrug Resistance protein
EXW38_RS01865	COG2309	aminopeptidase activity
EXW38_RS01885	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS01895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW38_RS01905	COG4807	Protein conserved in bacteria
EXW38_RS01930	COG1757	Na H antiporter
EXW38_RS01935	COG1473	amidohydrolase
EXW38_RS01955	COG0450	alkyl hydroperoxide reductase
EXW38_RS01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW38_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS01990	COG0492	ferredoxin-NADP+ reductase activity
EXW38_RS02000	COG0166	Belongs to the GPI family
EXW38_RS02025	COG5002	protein histidine kinase activity
EXW38_RS02040	COG3541	Predicted nucleotidyltransferase
EXW38_RS02045	COG0723	plastoquinol--plastocyanin reductase activity
EXW38_RS02045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_RS02055	COG0765	amino acid transport
EXW38_RS02060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS02065	COG1126	abc transporter atp-binding protein
EXW38_RS02070	COG0840	transmembrane signaling receptor activity
EXW38_RS02075	COG0277	FAD linked oxidase domain protein
EXW38_RS02080	COG0366	Alpha amylase catalytic
EXW38_RS02085	COG2190	(PTS) system
EXW38_RS02085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS02085	COG1263	PTS System
EXW38_RS02110	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW38_RS02115	COG0352	thiamine-phosphate diphosphorylase activity
EXW38_RS02120	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW38_RS02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_RS02145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_RS02150	COG1116	anion transmembrane transporter activity
EXW38_RS02155	COG0488	(ABC) transporter
EXW38_RS02180	COG2270	Major facilitator Superfamily
EXW38_RS02210	COG2310	stress, protein
EXW38_RS02215	COG2310	stress, protein
EXW38_RS02220	COG2310	stress, protein
EXW38_RS02225	COG0861	Integral membrane protein TerC family
EXW38_RS02235	COG3853	Toxic anion resistance protein (TelA)
EXW38_RS02245	COG4840	Belongs to the UPF0435 family
EXW38_RS02250	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW38_RS02260	COG1295	ribonuclease BN
EXW38_RS02265	COG2217	Heavy metal translocating P-type atpase
EXW38_RS02270	COG0697	spore germination
EXW38_RS02290	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS02305	COG3871	stress protein (general stress protein 26)
EXW38_RS02310	COG0387	Pfam Sodium calcium exchanger
EXW38_RS02320	COG0535	radical SAM domain protein
EXW38_RS02340	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW38_RS02345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EXW38_RS02350	COG0582	viral genome integration into host DNA
EXW38_RS02435	COG2002	toxin-antitoxin pair type II binding
EXW38_RS02520	COG0582	viral genome integration into host DNA
EXW38_RS02560	COG5484	DNA packaging
EXW38_RS02670	COG3829	transcription factor binding
EXW38_RS02680	COG0833	amino acid
EXW38_RS02685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_RS02710	COG1263	PTS System
EXW38_RS02710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS02715	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_RS02735	COG1216	Glycosyl transferase, family 2
EXW38_RS02745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_RS02745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW38_RS02765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW38_RS02770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW38_RS02785	COG1228	amidohydrolase
EXW38_RS02790	COG1090	epimerase
EXW38_RS02795	COG2137	regulation of response to DNA damage stimulus
EXW38_RS02820	COG1988	membrane-bound metal-dependent
EXW38_RS02825	COG1194	a g-specific adenine glycosylase
EXW38_RS02845	COG3557	Belongs to the UPF0374 family
EXW38_RS02850	COG1132	(ABC) transporter
EXW38_RS02855	COG4129	membrane
EXW38_RS02860	COG0067	glutamate synthase
EXW38_RS02860	COG0069	glutamate synthase activity
EXW38_RS02860	COG0070	glutamate synthase
EXW38_RS02865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW38_RS02870	COG4555	ABC transporter
EXW38_RS02890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW38_RS02895	COG0735	belongs to the Fur family
EXW38_RS03000	COG4974	Belongs to the 'phage' integrase family
EXW38_RS03020	COG4695	Portal protein
EXW38_RS03100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW38_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW38_RS03125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW38_RS03135	COG2766	serine protein kinase
EXW38_RS03155	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW38_RS03160	COG2268	Band 7 protein
EXW38_RS03165	COG3290	protein histidine kinase activity
EXW38_RS03170	COG4565	transcriptional regulatory protein
EXW38_RS03175	COG2851	Citrate transporter
EXW38_RS03195	COG0745	RESPONSE REGULATOR receiver
EXW38_RS03200	COG5002	protein histidine kinase activity
EXW38_RS03210	COG4990	cell redox homeostasis
EXW38_RS03220	COG3290	protein histidine kinase activity
EXW38_RS03225	COG4565	transcriptional regulatory protein
EXW38_RS03230	COG3493	citrate carrier protein
EXW38_RS03235	COG0281	malic enzyme
EXW38_RS03245	COG0697	spore germination
EXW38_RS03250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS03260	COG5002	protein histidine kinase activity
EXW38_RS03265	COG0745	RESPONSE REGULATOR receiver
EXW38_RS03270	COG0456	acetyltransferase
EXW38_RS03275	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW38_RS03280	COG3383	formate dehydrogenase (NAD+) activity
EXW38_RS03285	COG2427	Protein of unknown function (DUF1641)
EXW38_RS03305	COG0531	amino acid
EXW38_RS03315	COG0640	Transcriptional regulator
EXW38_RS03320	COG2217	Heavy metal translocating P-type atpase
EXW38_RS03325	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW38_RS03340	COG3227	Zinc metalloprotease (Elastase)
EXW38_RS03360	COG2720	vancomycin resistance protein
EXW38_RS03365	COG1316	TRANSCRIPTIONal
EXW38_RS03370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS03375	COG0346	lactoylglutathione lyase activity
EXW38_RS03380	COG1253	flavin adenine dinucleotide binding
EXW38_RS03385	COG1027	Aspartate ammonia-lyase
EXW38_RS03390	COG1620	l-lactate permease
EXW38_RS03395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_RS03410	COG3104	oligopeptide transport
EXW38_RS03415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS03420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS03440	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_RS03445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_RS03455	COG4548	von Willebrand factor, type A
EXW38_RS03460	COG0714	Associated with various cellular activities
EXW38_RS03485	COG0531	amino acid
EXW38_RS03490	COG2188	Transcriptional regulator
EXW38_RS03495	COG1263	PTS System
EXW38_RS03495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS03500	COG0366	Alpha amylase catalytic
EXW38_RS03520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_RS03525	COG1115	amino acid carrier protein
EXW38_RS03530	COG1126	abc transporter atp-binding protein
EXW38_RS03535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS03540	COG0765	amino acid transport
EXW38_RS03545	COG0765	amino acid transport
EXW38_RS03550	COG0833	amino acid
EXW38_RS03565	COG2378	regulation of single-species biofilm formation
EXW38_RS03570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW38_RS03575	COG5002	protein histidine kinase activity
EXW38_RS03590	COG0659	secondary active sulfate transmembrane transporter activity
EXW38_RS03615	COG0601	transmembrane transport
EXW38_RS03620	COG4608	Belongs to the ABC transporter superfamily
EXW38_RS03630	COG2271	Major facilitator Superfamily
EXW38_RS03635	COG1846	Transcriptional regulator
EXW38_RS03640	COG0477	Major facilitator Superfamily
EXW38_RS03645	COG1609	Transcriptional regulator
EXW38_RS03650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW38_RS03655	COG1869	D-ribose catabolic process
EXW38_RS03665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW38_RS03670	COG1879	ABC-type sugar transport system periplasmic component
EXW38_RS03700	COG1063	alcohol dehydrogenase
EXW38_RS03745	COG0840	transmembrane signaling receptor activity
EXW38_RS03750	COG3583	domain protein
EXW38_RS03750	COG3584	3D domain protein
EXW38_RS03755	COG1476	TRANSCRIPTIONal
EXW38_RS03775	COG3104	oligopeptide transport
EXW38_RS03780	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS03795	COG1113	amino acid transport
EXW38_RS03800	COG2252	PERMEase
EXW38_RS03815	COG2153	protein acetylation
EXW38_RS03825	COG0569	domain protein
EXW38_RS03825	COG0475	glutathione-regulated potassium exporter activity
EXW38_RS03835	COG1845	cytochrome c oxidase, subunit III
EXW38_RS03840	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW38_RS03845	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW38_RS03850	COG0833	amino acid
EXW38_RS03855	COG4990	cell redox homeostasis
EXW38_RS03870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_RS03875	COG0697	spore germination
EXW38_RS03880	COG0531	amino acid
EXW38_RS03895	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW38_RS03900	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW38_RS03910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW38_RS03915	COG0573	inorganic phosphate transmembrane transporter activity
EXW38_RS03920	COG0581	inorganic phosphate transmembrane transporter activity
EXW38_RS03930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW38_RS03975	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW38_RS04055	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW38_RS04070	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS04070	COG4991	sh3 domain protein
EXW38_RS04070	COG3103	Sh3 type 3 domain protein
EXW38_RS04075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW38_RS04080	COG1116	anion transmembrane transporter activity
EXW38_RS04085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_RS04090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_RS04095	COG0352	thiamine-phosphate diphosphorylase activity
EXW38_RS04100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_RS04105	COG2104	thiamine diphosphate biosynthetic process
EXW38_RS04110	COG2022	thiamine diphosphate biosynthetic process
EXW38_RS04115	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_RS04120	COG0351	phosphomethylpyrimidine kinase
EXW38_RS04150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW38_RS04155	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW38_RS04160	COG2205	protein histidine kinase activity
EXW38_RS04185	COG1136	(ABC) transporter
EXW38_RS04195	COG2252	PERMEase
EXW38_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS04260	COG0778	Nitroreductase
EXW38_RS04265	COG2719	SpoVR family
EXW38_RS04290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_RS04300	COG1937	Protein conserved in bacteria
EXW38_RS04305	COG0425	Belongs to the sulfur carrier protein TusA family
EXW38_RS04305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_RS04310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS04310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_RS04315	COG0425	Belongs to the sulfur carrier protein TusA family
EXW38_RS04320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_RS04325	COG2210	Belongs to the sulfur carrier protein TusA family
EXW38_RS04330	COG0730	response to heat
EXW38_RS04340	COG1316	TRANSCRIPTIONal
EXW38_RS04345	COG0604	alcohol dehydrogenase
EXW38_RS04350	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW38_RS04360	COG2814	Major facilitator Superfamily
EXW38_RS04370	COG3711	transcriptional antiterminator
EXW38_RS04370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_RS04375	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_RS04380	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS04400	COG3584	3D domain protein
EXW38_RS04400	COG1388	LysM domain
EXW38_RS04405	COG0577	efflux transmembrane transporter activity
EXW38_RS04410	COG1136	(ABC) transporter
EXW38_RS04420	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW38_RS04435	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS04440	COG3546	catalase activity
EXW38_RS04470	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS04500	COG0531	amino acid
EXW38_RS04505	COG0475	glutathione-regulated potassium exporter activity
EXW38_RS04525	COG1263	PTS System
EXW38_RS04525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS04535	COG2259	Doxx family
EXW38_RS04570	COG0531	amino acid
EXW38_RS04580	COG0351	phosphomethylpyrimidine kinase
EXW38_RS04585	COG1757	Na H antiporter
EXW38_RS04590	COG4496	protein, YerC YecD
EXW38_RS04605	COG1522	sequence-specific DNA binding
EXW38_RS04615	COG0300	oxidoreductase activity
EXW38_RS04630	COG2076	Multidrug Resistance protein
EXW38_RS04635	COG1309	transcriptional regulator
EXW38_RS04640	COG2814	Major facilitator Superfamily
EXW38_RS04645	COG1733	regulation of RNA biosynthetic process
EXW38_RS04655	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS04680	COG4473	ABC transporter
EXW38_RS04685	COG0531	amino acid
EXW38_RS04690	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EXW38_RS04695	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS04700	COG1132	(ABC) transporter
EXW38_RS04705	COG1132	(ABC) transporter
EXW38_RS04710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS04715	COG0765	amino acid transport
EXW38_RS04720	COG1126	abc transporter atp-binding protein
EXW38_RS04735	COG0189	ligase activity
EXW38_RS04745	COG4399	Belongs to the UPF0754 family
EXW38_RS04750	COG3679	Belongs to the UPF0342 family
EXW38_RS04765	COG0028	Belongs to the TPP enzyme family
EXW38_RS04770	COG3527	Alpha-acetolactate decarboxylase
EXW38_RS04775	COG0463	Glycosyl transferase, family 2
EXW38_RS04780	COG1216	Glycosyl transferase, family 2
EXW38_RS04785	COG2094	Belongs to the DNA glycosylase MPG family
EXW38_RS04790	COG0561	phosphatase activity
EXW38_RS04795	COG3409	Peptidoglycan-binding domain 1 protein
EXW38_RS04795	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS04800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW38_RS04805	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS04815	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS04825	COG0789	Transcriptional regulator
EXW38_RS04825	COG4978	Transcriptional regulator
EXW38_RS04835	COG0659	secondary active sulfate transmembrane transporter activity
EXW38_RS04840	COG2244	polysaccharide biosynthetic process
EXW38_RS04860	COG1024	Enoyl-CoA hydratase
EXW38_RS04875	COG1363	Peptidase, m42
EXW38_RS04895	COG2318	DinB family
EXW38_RS04905	COG1113	amino acid transport
EXW38_RS04910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS04930	COG0579	oxidoreductase
EXW38_RS04935	COG2226	methyltransferase
EXW38_RS04940	COG3290	protein histidine kinase activity
EXW38_RS04940	COG3829	transcription factor binding
EXW38_RS04950	COG1301	dicarboxylic acid transport
EXW38_RS05010	COG0477	Major facilitator Superfamily
EXW38_RS05015	COG3290	protein histidine kinase activity
EXW38_RS05020	COG4565	transcriptional regulatory protein
EXW38_RS05025	COG3181	Tripartite tricarboxylate transporter family receptor
EXW38_RS05060	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_RS05085	COG1842	Phage shock protein A
EXW38_RS05095	COG0477	Major facilitator Superfamily
EXW38_RS05145	COG1183	phosphatidylcholine synthase activity
EXW38_RS05160	COG2814	Major facilitator Superfamily
EXW38_RS05165	COG0640	Transcriptional regulator
EXW38_RS05195	COG2376	Dihydroxyacetone kinase
EXW38_RS05205	COG2376	Dihydroxyacetone kinase
EXW38_RS05230	COG2755	lipolytic protein G-D-S-L family
EXW38_RS05230	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW38_RS05245	COG2720	vancomycin resistance protein
EXW38_RS05250	COG1335	isochorismatase
EXW38_RS05265	COG2373	Large extracellular alpha-helical protein
EXW38_RS05305	COG0076	glutamate decarboxylase activity
EXW38_RS05315	COG5658	integral membrane protein
EXW38_RS05330	COG1595	DNA-templated transcription, initiation
EXW38_RS05365	COG2807	transmembrane transport
EXW38_RS05370	COG2186	Transcriptional regulator
EXW38_RS05385	COG4585	Histidine kinase
EXW38_RS05390	COG2197	response regulator
EXW38_RS05415	COG0420	3'-5' exonuclease activity
EXW38_RS05420	COG4717	serine-type aminopeptidase activity
EXW38_RS05425	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW38_RS05435	COG0346	lactoylglutathione lyase activity
EXW38_RS05440	COG2267	carboxylic ester hydrolase activity
EXW38_RS05450	COG2140	Oxalate decarboxylase
EXW38_RS05455	COG3620	sequence-specific DNA binding
EXW38_RS05460	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW38_RS05465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW38_RS05470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW38_RS05475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW38_RS05480	COG1595	DNA-templated transcription, initiation
EXW38_RS05500	COG3973	AAA domain
EXW38_RS05530	COG0537	adenosine 5'-monophosphoramidase activity
EXW38_RS05535	COG1131	(ABC) transporter
EXW38_RS05540	COG4473	ABC transporter
EXW38_RS05570	COG0247	lactate metabolic process
EXW38_RS05575	COG1139	Iron-sulfur cluster binding protein
EXW38_RS05580	COG1556	Lactate utilization protein
EXW38_RS05615	COG1309	transcriptional regulator
EXW38_RS05625	COG3402	PFAM membrane-flanked domain
EXW38_RS05630	COG3428	Bacterial PH domain
EXW38_RS05655	COG3402	PFAM membrane-flanked domain
EXW38_RS05660	COG3428	Bacterial PH domain
EXW38_RS05665	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_RS05670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_RS05675	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW38_RS05680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW38_RS05685	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW38_RS05725	COG1309	transcriptional regulator
EXW38_RS05735	COG1216	Glycosyl transferase, family 2
EXW38_RS05735	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS05755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS05765	COG2378	regulation of single-species biofilm formation
EXW38_RS05770	COG1609	Transcriptional regulator
EXW38_RS05780	COG1234	tRNA 3'-trailer cleavage
EXW38_RS05785	COG0095	Lipoate-protein ligase
EXW38_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS05820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW38_RS05825	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW38_RS05830	COG4208	sulfate ABC transporter
EXW38_RS05840	COG1408	metallophosphoesterase
EXW38_RS05845	COG1078	dGTPase activity
EXW38_RS05895	COG1595	DNA-templated transcription, initiation
EXW38_RS05900	COG2207	Transcriptional regulator
EXW38_RS05900	COG3708	Transcriptional regulator
EXW38_RS05905	COG2205	protein histidine kinase activity
EXW38_RS05910	COG0745	RESPONSE REGULATOR receiver
EXW38_RS05935	COG0501	Belongs to the peptidase M48B family
EXW38_RS05940	COG0697	spore germination
EXW38_RS05950	COG2373	Large extracellular alpha-helical protein
EXW38_RS05955	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW38_RS05960	COG2224	Isocitrate lyase
EXW38_RS05970	COG1278	Cold shock
EXW38_RS05980	COG4903	ComK protein
EXW38_RS05985	COG0398	Pfam SNARE associated Golgi protein
EXW38_RS06015	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW38_RS06020	COG1074	ATP-dependent DNA helicase activity
EXW38_RS06070	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_RS06095	COG0367	asparagine synthase
EXW38_RS06105	COG0753	catalase activity
EXW38_RS06110	COG0004	ammonium transporteR
EXW38_RS06120	COG1666	GTP binding
EXW38_RS06125	COG2996	Protein conserved in bacteria
EXW38_RS06140	COG1329	Transcriptional regulator
EXW38_RS06170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW38_RS06180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS06195	COG0561	phosphatase activity
EXW38_RS06215	COG2267	carboxylic ester hydrolase activity
EXW38_RS06230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_RS06235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW38_RS06240	COG5504	Zn-dependent protease
EXW38_RS06250	COG0180	Tryptophanyl-tRNA synthetase
EXW38_RS06260	COG4166	transmembrane transport
EXW38_RS06265	COG0601	transmembrane transport
EXW38_RS06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW38_RS06275	COG0444	Belongs to the ABC transporter superfamily
EXW38_RS06280	COG4608	Belongs to the ABC transporter superfamily
EXW38_RS06285	COG0534	Mate efflux family protein
EXW38_RS06290	COG4166	transmembrane transport
EXW38_RS06305	COG0861	Integral membrane protein TerC family
EXW38_RS06310	COG4862	establishment of competence for transformation
EXW38_RS06315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_RS06325	COG1164	Oligoendopeptidase f
EXW38_RS06335	COG2346	COG2346, Truncated hemoglobins
EXW38_RS06340	COG4116	CYTH
EXW38_RS06350	COG2357	RelA SpoT domain protein
EXW38_RS06360	COG0564	pseudouridine synthase activity
EXW38_RS06370	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW38_RS06375	COG0772	Belongs to the SEDS family
EXW38_RS06385	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW38_RS06400	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW38_RS06445	COG2153	protein acetylation
EXW38_RS06450	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW38_RS06455	COG2382	esterase
EXW38_RS06480	COG5492	domain, Protein
EXW38_RS06485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_RS06495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW38_RS06495	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW38_RS06500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW38_RS06505	COG0134	indole-3-glycerol-phosphate synthase activity
EXW38_RS06510	COG0135	phosphoribosylanthranilate isomerase activity
EXW38_RS06520	COG0159	tryptophan synthase activity
EXW38_RS06530	COG1620	l-lactate permease
EXW38_RS06535	COG5634	Uncharacterized conserved protein (DUF2278)
EXW38_RS06575	COG2226	methyltransferase
EXW38_RS06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW38_RS06600	COG0567	Dehydrogenase, E1 component
EXW38_RS06605	COG1476	TRANSCRIPTIONal
EXW38_RS06650	COG1686	Belongs to the peptidase S11 family
EXW38_RS06655	COG0681	Belongs to the peptidase S26 family
EXW38_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS06700	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW38_RS06705	COG1177	transmembrane transport
EXW38_RS06710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW38_RS06720	COG2409	Drug exporters of the RND superfamily
EXW38_RS06730	COG0564	pseudouridine synthase activity
EXW38_RS06740	COG2340	Cysteine-rich secretory protein family
EXW38_RS06745	COG0247	lactate metabolic process
EXW38_RS06750	COG0277	FAD linked oxidase domain protein
EXW38_RS06755	COG3835	regulator
EXW38_RS06765	COG0745	RESPONSE REGULATOR receiver
EXW38_RS06770	COG3850	Histidine kinase
EXW38_RS06770	COG5002	protein histidine kinase activity
EXW38_RS06775	COG2186	Transcriptional regulator
EXW38_RS06790	COG1556	Lactate utilization protein
EXW38_RS06795	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW38_RS06810	COG2116	formate transmembrane transporter activity
EXW38_RS06815	COG0861	Integral membrane protein TerC family
EXW38_RS06820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_RS06830	COG2030	dehydratase
EXW38_RS06855	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW38_RS06865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_RS06880	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW38_RS06885	COG3842	ATPase activity
EXW38_RS06895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW38_RS06900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW38_RS06910	COG1349	DNA-binding transcription factor activity
EXW38_RS06920	COG0235	Class ii aldolase
EXW38_RS06930	COG2861	carbohydrate metabolic process
EXW38_RS06940	COG3852	Histidine kinase
EXW38_RS06945	COG1846	Transcriptional regulator
EXW38_RS06955	COG2318	DinB family
EXW38_RS06960	COG5002	protein histidine kinase activity
EXW38_RS06970	COG0720	synthase
EXW38_RS06980	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW38_RS06985	COG4873	Protein conserved in bacteria
EXW38_RS07000	COG0456	acetyltransferase
EXW38_RS07015	COG1780	Probably involved in ribonucleotide reductase function
EXW38_RS07030	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW38_RS07035	COG0531	amino acid
EXW38_RS07050	COG2204	response regulator
EXW38_RS07055	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS07065	COG1725	Transcriptional regulator
EXW38_RS07070	COG1131	(ABC) transporter
EXW38_RS07080	COG1131	(ABC) transporter
EXW38_RS07085	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_RS07090	COG1266	CAAX protease self-immunity
EXW38_RS07100	COG1522	sequence-specific DNA binding
EXW38_RS07110	COG1335	isochorismatase
EXW38_RS07120	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_RS07125	COG2070	2-Nitropropane dioxygenase
EXW38_RS07130	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW38_RS07135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_RS07140	COG1696	Membrane protein involved in D-alanine export
EXW38_RS07165	COG0716	FMN binding
EXW38_RS07180	COG3173	Aminoglycoside phosphotransferase
EXW38_RS07200	COG0534	Mate efflux family protein
EXW38_RS07220	COG1846	Transcriptional regulator
EXW38_RS07235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW38_RS07245	COG3874	Sporulation protein YtfJ
EXW38_RS07265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS07270	COG0028	Belongs to the TPP enzyme family
EXW38_RS07275	COG0440	acetolactate synthase activity
EXW38_RS07285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_RS07295	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW38_RS07305	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW38_RS07310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW38_RS07320	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW38_RS07325	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW38_RS07330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW38_RS07335	COG0107	imidazoleglycerol-phosphate synthase activity
EXW38_RS07345	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW38_RS07350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW38_RS07365	COG1183	phosphatidylcholine synthase activity
EXW38_RS07370	COG1368	sulfuric ester hydrolase activity
EXW38_RS07380	COG0019	diaminopimelate decarboxylase activity
EXW38_RS07395	COG2046	Belongs to the sulfate adenylyltransferase family
EXW38_RS07400	COG0529	Catalyzes the synthesis of activated sulfate
EXW38_RS07405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW38_RS07425	COG1648	precorrin-2 dehydrogenase activity
EXW38_RS07430	COG0733	neurotransmitter:sodium symporter activity
EXW38_RS07455	COG1757	Na H antiporter
EXW38_RS07470	COG4758	membrane
EXW38_RS07475	COG4585	Histidine kinase
EXW38_RS07480	COG2197	response regulator
EXW38_RS07490	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS07500	COG2226	methyltransferase
EXW38_RS07540	COG0730	response to heat
EXW38_RS07545	COG0306	phosphate transporter
EXW38_RS07550	COG1392	Phosphate transport regulator
EXW38_RS07555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_RS07570	COG3852	Histidine kinase
EXW38_RS07575	COG1801	Protein of unknown function DUF72
EXW38_RS07590	COG0582	viral genome integration into host DNA
EXW38_RS07595	COG5002	protein histidine kinase activity
EXW38_RS07610	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW38_RS07610	COG0392	lysyltransferase activity
EXW38_RS07625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW38_RS07630	COG1686	Belongs to the peptidase S11 family
EXW38_RS07635	COG2715	membrane protein required for spore maturation
EXW38_RS07640	COG0700	Nucleoside recognition
EXW38_RS07645	COG1187	pseudouridine synthase activity
EXW38_RS07655	COG1333	cytochrome c biogenesis protein
EXW38_RS07660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW38_RS07665	COG0745	RESPONSE REGULATOR receiver
EXW38_RS07670	COG5002	protein histidine kinase activity
EXW38_RS07675	COG2096	Adenosyltransferase
EXW38_RS07680	COG4942	peptidase
EXW38_RS07690	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW38_RS07695	COG1141	Ferredoxin
EXW38_RS07700	COG4955	Helix-turn-helix domain
EXW38_RS07705	COG0514	ATP-dependent DNA helicase (RecQ)
EXW38_RS07710	COG1266	CAAX protease self-immunity
EXW38_RS07720	COG1408	metallophosphoesterase
EXW38_RS07735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW38_RS07755	COG0492	ferredoxin-NADP+ reductase activity
EXW38_RS07760	COG0252	asparaginase activity
EXW38_RS07770	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW38_RS07780	COG1304	FMN binding
EXW38_RS07820	COG1160	GTP binding
EXW38_RS07825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW38_RS07845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_RS07860	COG0142	geranyltranstransferase activity
EXW38_RS07865	COG2226	methyltransferase
EXW38_RS07870	COG0142	geranyltranstransferase activity
EXW38_RS07885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW38_RS07895	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW38_RS07900	COG0457	Tetratricopeptide repeat
EXW38_RS07905	COG5582	Belongs to the UPF0302 family
EXW38_RS07920	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW38_RS07925	COG2010	Cytochrome c
EXW38_RS07925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW38_RS07930	COG4347	Protein of unknown function (DUF1405)
EXW38_RS07945	COG2738	Putative neutral zinc metallopeptidase
EXW38_RS07955	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS07960	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW38_RS07965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW38_RS07970	COG1803	Methylglyoxal synthase
EXW38_RS07975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_RS07980	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS07985	COG0617	tRNA 3'-terminal CCA addition
EXW38_RS07995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW38_RS08000	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW38_RS08010	COG1199	ATP-dependent helicase activity
EXW38_RS08010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW38_RS08030	COG3935	DnaD domain protein
EXW38_RS08035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW38_RS08045	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW38_RS08045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_RS08050	COG3331	DNA recombination
EXW38_RS08085	COG4474	Belongs to the UPF0398 family
EXW38_RS08090	COG3599	regulation of cell shape
EXW38_RS08100	COG0116	Belongs to the methyltransferase superfamily
EXW38_RS08110	COG1199	ATP-dependent helicase activity
EXW38_RS08115	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW38_RS08125	COG0024	Methionine aminopeptidase
EXW38_RS08135	COG2233	PERMEase
EXW38_RS08140	COG2311	Membrane
EXW38_RS08145	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_RS08155	COG0456	acetyltransferase
EXW38_RS08165	COG2897	thiosulfate sulfurtransferase activity
EXW38_RS08205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_RS08245	COG0328	RNA-DNA hybrid ribonuclease activity
EXW38_RS08290	COG3403	YqcI/YcgG family
EXW38_RS08295	COG1280	lysine exporter protein (LysE YggA)
EXW38_RS08310	COG3162	membrane
EXW38_RS08315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW38_RS08320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_RS08330	COG0475	glutathione-regulated potassium exporter activity
EXW38_RS08335	COG4978	Transcriptional regulator
EXW38_RS08335	COG0789	Transcriptional regulator
EXW38_RS08340	COG0534	Mate efflux family protein
EXW38_RS08345	COG2323	membrane
EXW38_RS08350	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW38_RS08370	COG1609	Transcriptional regulator
EXW38_RS08380	COG1175	transmembrane transport
EXW38_RS08385	COG0395	ABC-type sugar transport system, permease component
EXW38_RS08390	COG5578	integral membrane protein
EXW38_RS08400	COG1486	melibiose metabolic process
EXW38_RS08415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EXW38_RS08420	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW38_RS08425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_RS08460	COG1923	regulation of RNA biosynthetic process
EXW38_RS08470	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW38_RS08475	COG1360	Flagellar Motor Protein
EXW38_RS08480	COG2201	protein-glutamate methylesterase activity
EXW38_RS08485	COG0643	Histidine kinase
EXW38_RS08485	COG2198	Histidine kinase
EXW38_RS08490	COG1776	CheC inhibitor of MCP methylation
EXW38_RS08490	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_RS08505	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW38_RS08525	COG1256	bacterial-type flagellum assembly
EXW38_RS08530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW38_RS08550	COG1815	bacterial-type flagellum-dependent cell motility
EXW38_RS08555	COG1558	bacterial-type flagellum-dependent cell motility
EXW38_RS08565	COG1766	The M ring may be actively involved in energy transduction
EXW38_RS08570	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_RS08580	COG1157	protein secretion by the type III secretion system
EXW38_RS08600	COG1749	Flagellar hook protein flgE
EXW38_RS08615	COG0784	Response regulator, receiver
EXW38_RS08615	COG0835	chemotaxis
EXW38_RS08625	COG0861	Integral membrane protein TerC family
EXW38_RS08635	COG3383	formate dehydrogenase (NAD+) activity
EXW38_RS08640	COG2427	Protein of unknown function (DUF1641)
EXW38_RS08645	COG5609	conserved protein (DUF2294)
EXW38_RS08650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW38_RS08665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_RS08670	COG0303	'Molybdopterin
EXW38_RS08675	COG0314	molybdopterin synthase activity
EXW38_RS08680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW38_RS08690	COG0489	protein tyrosine kinase activity
EXW38_RS08695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW38_RS08700	COG0741	lytic transglycosylase activity
EXW38_RS08710	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_RS08715	COG1776	CheC inhibitor of MCP methylation
EXW38_RS08715	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW38_RS08725	COG1338	Plays a role in the flagellum-specific transport system
EXW38_RS08730	COG1987	bacterial-type flagellum assembly
EXW38_RS08740	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW38_RS08745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW38_RS08750	COG1419	protein localization to endoplasmic reticulum
EXW38_RS08755	COG4787	bacterial-type flagellum-dependent cell motility
EXW38_RS08790	COG1309	transcriptional regulator
EXW38_RS08805	COG0412	Dienelactone hydrolase
EXW38_RS08810	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_RS08825	COG3764	Sortase (surface protein transpeptidase)
EXW38_RS08830	COG3764	Sortase (surface protein transpeptidase)
EXW38_RS08855	COG0583	DNA-binding transcription factor activity
EXW38_RS08860	COG3842	ATPase activity
EXW38_RS08865	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW38_RS08920	COG1846	Transcriptional regulator
EXW38_RS08930	COG0367	asparagine synthase
EXW38_RS08960	COG1757	Na H antiporter
EXW38_RS08970	COG0277	FAD linked oxidase domain protein
EXW38_RS08990	COG0534	Mate efflux family protein
EXW38_RS08995	COG3340	Belongs to the peptidase S51 family
EXW38_RS09015	COG0785	Cytochrome C biogenesis protein
EXW38_RS09035	COG3048	D-serine ammonia-lyase activity
EXW38_RS09040	COG2733	membrane
EXW38_RS09075	COG1131	(ABC) transporter
EXW38_RS09095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_RS09100	COG0528	UMP kinase activity
EXW38_RS09110	COG1027	Aspartate ammonia-lyase
EXW38_RS09115	COG0281	malic enzyme
EXW38_RS09120	COG4191	Histidine kinase
EXW38_RS09125	COG0784	Response regulator, receiver
EXW38_RS09130	COG1846	Transcriptional regulator
EXW38_RS09140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_RS09150	COG2502	aspartate--ammonia ligase
EXW38_RS09155	COG3620	sequence-specific DNA binding
EXW38_RS09195	COG1695	Transcriptional regulator
EXW38_RS09210	COG0477	Major facilitator Superfamily
EXW38_RS09220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_RS09230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW38_RS09235	COG4166	transmembrane transport
EXW38_RS09240	COG2223	nitrite transmembrane transporter activity
EXW38_RS09245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_RS09260	COG2244	polysaccharide biosynthetic process
EXW38_RS09265	COG0733	neurotransmitter:sodium symporter activity
EXW38_RS09275	COG5566	PFAM Mor transcription activator
EXW38_RS09280	COG2323	membrane
EXW38_RS09295	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_RS09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW38_RS09330	COG2814	Major facilitator Superfamily
EXW38_RS09335	COG3384	dioxygenase
EXW38_RS09370	COG4166	transmembrane transport
EXW38_RS09400	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS09410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS09420	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW38_RS09425	COG1054	Belongs to the UPF0176 family
EXW38_RS09435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW38_RS09440	COG0531	amino acid
EXW38_RS09460	COG1280	lysine exporter protein (LysE YggA)
EXW38_RS09475	COG2390	Transcriptional regulator
EXW38_RS09480	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW38_RS09485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS09490	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW38_RS09505	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW38_RS09530	COG2267	carboxylic ester hydrolase activity
EXW38_RS09535	COG0583	DNA-binding transcription factor activity
EXW38_RS09555	COG0006	proline dipeptidase activity
EXW38_RS09565	COG2132	Multicopper oxidase
EXW38_RS09575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW38_RS09585	COG0583	DNA-binding transcription factor activity
EXW38_RS09605	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS09615	COG1276	copper resistance
EXW38_RS09615	COG2372	response to copper ion
EXW38_RS09620	COG4549	nuclear export factor GLE1
EXW38_RS09630	COG0697	spore germination
EXW38_RS09635	COG0583	DNA-binding transcription factor activity
EXW38_RS09640	COG1959	2 iron, 2 sulfur cluster binding
EXW38_RS09645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW38_RS09660	COG0628	permease
EXW38_RS09675	COG1231	oxidoreductase activity
EXW38_RS09680	COG0523	cobalamin synthesis protein
EXW38_RS09690	COG0411	ABC transporter
EXW38_RS09710	COG0583	DNA-binding transcription factor activity
EXW38_RS09720	COG1942	4-Oxalocrotonate Tautomerase
EXW38_RS09735	COG0346	lactoylglutathione lyase activity
EXW38_RS09745	COG1271	oxidase subunit
EXW38_RS09750	COG1294	oxidase, subunit
EXW38_RS09755	COG4988	ABC transporter
EXW38_RS09760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW38_RS09785	COG1686	Belongs to the peptidase S11 family
EXW38_RS09800	COG1388	LysM domain
EXW38_RS09800	COG0791	NLP P60 protein
EXW38_RS09810	COG1132	(ABC) transporter
EXW38_RS09815	COG0745	RESPONSE REGULATOR receiver
EXW38_RS09820	COG5002	protein histidine kinase activity
EXW38_RS09825	COG0300	oxidoreductase activity
EXW38_RS09830	COG4122	O-methyltransferase activity
EXW38_RS09860	COG0460	homoserine dehydrogenase
EXW38_RS09870	COG0083	homoserine kinase activity
EXW38_RS09885	COG1316	TRANSCRIPTIONal
EXW38_RS09900	COG1285	pathogenesis
EXW38_RS09925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_RS09935	COG1082	Xylose isomerase domain protein TIM barrel
EXW38_RS09945	COG2814	Major facilitator Superfamily
EXW38_RS09950	COG1279	arginine transmembrane transporter activity
EXW38_RS09955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS09965	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW38_RS10000	COG0577	efflux transmembrane transporter activity
EXW38_RS10005	COG2002	toxin-antitoxin pair type II binding
EXW38_RS10010	COG1404	Belongs to the peptidase S8 family
EXW38_RS10020	COG3842	ATPase activity
EXW38_RS10025	COG2508	Transcriptional regulator
EXW38_RS10035	COG1653	transport
EXW38_RS10040	COG1175	transmembrane transport
EXW38_RS10045	COG0395	ABC-type sugar transport system, permease component
EXW38_RS10050	COG5426	von Willebrand factor, type A
EXW38_RS10060	COG1940	carbohydrate kinase activity
EXW38_RS10065	COG2222	sugar isomerase
EXW38_RS10075	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW38_RS10080	COG3684	Belongs to the aldolase LacD family
EXW38_RS10085	COG0366	Alpha amylase catalytic
EXW38_RS10090	COG0366	Alpha amylase catalytic
EXW38_RS10095	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EXW38_RS10140	COG3949	Membrane
EXW38_RS10145	COG0783	Belongs to the Dps family
EXW38_RS10160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW38_RS10170	COG1231	oxidoreductase activity
EXW38_RS10175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS10180	COG4989	oxidoreductase activity
EXW38_RS10185	COG0523	cobalamin synthesis protein
EXW38_RS10190	COG0456	acetyltransferase
EXW38_RS10195	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW38_RS10205	COG0702	epimerase
EXW38_RS10215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW38_RS10225	COG4166	transmembrane transport
EXW38_RS10230	COG0346	lactoylglutathione lyase activity
EXW38_RS10240	COG0406	alpha-ribazole phosphatase activity
EXW38_RS10250	COG5337	Spore coat protein CotH
EXW38_RS10255	COG1051	belongs to the nudix hydrolase family
EXW38_RS10260	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS10265	COG2244	polysaccharide biosynthetic process
EXW38_RS10275	COG0701	Predicted permease
EXW38_RS10280	COG3689	TIGRFAM TIGR03943 family protein
EXW38_RS10285	COG1607	acyl-coa hydrolase
EXW38_RS10295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_RS10310	COG0702	epimerase
EXW38_RS10315	COG2839	Protein conserved in bacteria
EXW38_RS10320	COG1253	flavin adenine dinucleotide binding
EXW38_RS10335	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS10340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_RS10355	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS10365	COG1876	peptidase activity
EXW38_RS10380	COG2211	Major facilitator Superfamily
EXW38_RS10395	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS10405	COG0561	phosphatase activity
EXW38_RS10415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW38_RS10430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS10435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS10460	COG0456	acetyltransferase
EXW38_RS10535	COG3874	Sporulation protein YtfJ
EXW38_RS10560	COG2226	methyltransferase
EXW38_RS10580	COG0346	lactoylglutathione lyase activity
EXW38_RS10590	COG0604	alcohol dehydrogenase
EXW38_RS10595	COG1595	DNA-templated transcription, initiation
EXW38_RS10620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW38_RS10620	COG0426	domain, Protein
EXW38_RS10630	COG0386	Belongs to the glutathione peroxidase family
EXW38_RS10635	COG1305	Transglutaminase-like
EXW38_RS10640	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW38_RS10645	COG0714	Associated with various cellular activities
EXW38_RS10660	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW38_RS10665	COG1140	nitrate reductase beta subunit
EXW38_RS10670	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW38_RS10675	COG2181	nitrate reductase activity
EXW38_RS10680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW38_RS10685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW38_RS10690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_RS10695	COG0303	'Molybdopterin
EXW38_RS10700	COG0314	molybdopterin synthase activity
EXW38_RS10710	COG2223	nitrite transmembrane transporter activity
EXW38_RS10715	COG1648	precorrin-2 dehydrogenase activity
EXW38_RS10725	COG1587	Uroporphyrinogen-III synthase
EXW38_RS10725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW38_RS10730	COG2146	nitrite reductase [NAD(P)H] activity
EXW38_RS10735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW38_RS10740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW38_RS10765	COG2359	stage V sporulation protein S
EXW38_RS10775	COG1418	mRNA catabolic process
EXW38_RS10780	COG0488	(ABC) transporter
EXW38_RS10800	COG1413	lyase activity
EXW38_RS10815	COG2136	Putative SAM-dependent methyltransferase
EXW38_RS10815	COG2521	methyltransferase
EXW38_RS10820	COG0018	arginyl-trna synthetase
EXW38_RS10865	COG0017	Asparaginyl-tRNA synthetase
EXW38_RS10885	COG1674	ftsk spoiiie
EXW38_RS10935	COG0733	neurotransmitter:sodium symporter activity
EXW38_RS10960	COG2610	gluconate transmembrane transporter activity
EXW38_RS10965	COG1454	alcohol dehydrogenase
EXW38_RS10975	COG0456	acetyltransferase
EXW38_RS10980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW38_RS10990	COG1131	(ABC) transporter
EXW38_RS10995	COG4473	ABC transporter
EXW38_RS11005	COG0546	phosphoglycolate phosphatase activity
EXW38_RS11030	COG0671	phosphoesterase, PA-phosphatase related
EXW38_RS11050	COG0768	penicillin binding
EXW38_RS11065	COG1272	protein, Hemolysin III
EXW38_RS11070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW38_RS11075	COG0805	protein transport
EXW38_RS11085	COG1307	EDD domain protein, DegV family
EXW38_RS11090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW38_RS11095	COG1999	signal sequence binding
EXW38_RS11100	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW38_RS11105	COG0367	asparagine synthase
EXW38_RS11120	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS11125	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS11130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS11145	COG1335	isochorismatase
EXW38_RS11150	COG0668	transmembrane transport
EXW38_RS11155	COG2203	Gaf domain
EXW38_RS11155	COG4585	Histidine kinase
EXW38_RS11160	COG2197	response regulator
EXW38_RS11165	COG1737	Transcriptional regulator
EXW38_RS11170	COG1064	alcohol dehydrogenase
EXW38_RS11185	COG1070	Carbohydrate kinase
EXW38_RS11195	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW38_RS11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW38_RS11255	COG1484	DNA-dependent DNA replication
EXW38_RS11295	COG0582	viral genome integration into host DNA
EXW38_RS11425	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW38_RS11460	COG1125	glycine betaine transport
EXW38_RS11460	COG0517	IMP dehydrogenase activity
EXW38_RS11465	COG1174	glycine betaine transport
EXW38_RS11500	COG1253	flavin adenine dinucleotide binding
EXW38_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS11510	COG5506	Protein of unknown function (DUF1694)
EXW38_RS11525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_RS11530	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW38_RS11535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW38_RS11540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_RS11545	COG0456	acetyltransferase
EXW38_RS11550	COG3829	transcription factor binding
EXW38_RS11555	COG1509	lysine 2,3-aminomutase activity
EXW38_RS11565	COG4479	Belongs to the UPF0346 family
EXW38_RS11590	COG4991	sh3 domain protein
EXW38_RS11590	COG3064	Membrane
EXW38_RS11590	COG0515	serine threonine protein kinase
EXW38_RS11600	COG0671	phosphoesterase, PA-phosphatase related
EXW38_RS11605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW38_RS11610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_RS11615	COG0582	viral genome integration into host DNA
EXW38_RS11675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW38_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS11720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_RS11720	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW38_RS11730	COG2814	Major facilitator Superfamily
EXW38_RS11735	COG0372	Belongs to the citrate synthase family
EXW38_RS11740	COG2079	MmgE PrpD family protein
EXW38_RS11745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW38_RS11750	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS11755	COG2084	Dehydrogenase
EXW38_RS11760	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS11765	COG1280	lysine exporter protein (LysE YggA)
EXW38_RS11770	COG1024	Enoyl-CoA hydratase
EXW38_RS11785	COG0420	3'-5' exonuclease activity
EXW38_RS11790	COG0419	ATPase involved in DNA repair
EXW38_RS11810	COG2223	nitrite transmembrane transporter activity
EXW38_RS11815	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS11820	COG1169	isochorismate synthase
EXW38_RS11825	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW38_RS11830	COG1535	isochorismatase
EXW38_RS11830	COG3433	isochorismatase activity
EXW38_RS11835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW38_RS11840	COG3251	PFAM MbtH domain protein
EXW38_RS11845	COG2814	Major facilitator Superfamily
EXW38_RS11860	COG0776	regulation of translation
EXW38_RS11870	COG1115	amino acid carrier protein
EXW38_RS11885	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_RS11895	COG1187	pseudouridine synthase activity
EXW38_RS11900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW38_RS11925	COG1136	(ABC) transporter
EXW38_RS11935	COG0596	Alpha beta hydrolase
EXW38_RS11950	COG0028	Belongs to the TPP enzyme family
EXW38_RS11980	COG1253	flavin adenine dinucleotide binding
EXW38_RS12025	COG1846	Transcriptional regulator
EXW38_RS12035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS12040	COG1309	transcriptional regulator
EXW38_RS12050	COG0697	spore germination
EXW38_RS12055	COG0531	amino acid
EXW38_RS12070	COG1247	-acetyltransferase
EXW38_RS12080	COG0697	spore germination
EXW38_RS12105	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW38_RS12120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS12145	COG0561	phosphatase activity
EXW38_RS12155	COG0583	DNA-binding transcription factor activity
EXW38_RS12160	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW38_RS12195	COG0583	DNA-binding transcription factor activity
EXW38_RS12200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW38_RS12205	COG2258	MOSC domain
EXW38_RS12220	COG1132	(ABC) transporter
EXW38_RS12225	COG1132	(ABC) transporter
EXW38_RS12240	COG1396	sequence-specific DNA binding
EXW38_RS12325	COG1309	transcriptional regulator
EXW38_RS12340	COG1136	(ABC) transporter
EXW38_RS12340	COG0577	efflux transmembrane transporter activity
EXW38_RS12345	COG3615	Tellurite resistance protein tehB
EXW38_RS12345	COG0500	methyltransferase
EXW38_RS12355	COG0693	protein deglycase activity
EXW38_RS12415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_RS12420	COG0110	maltose O-acetyltransferase activity
EXW38_RS12425	COG1686	Belongs to the peptidase S11 family
EXW38_RS12475	COG0768	penicillin binding
EXW38_RS12480	COG1595	DNA-templated transcription, initiation
EXW38_RS12490	COG0768	penicillin binding
EXW38_RS12495	COG0768	penicillin binding
EXW38_RS12515	COG1136	(ABC) transporter
EXW38_RS12550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS12560	COG5002	protein histidine kinase activity
EXW38_RS12590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS12605	COG0697	spore germination
EXW38_RS12625	COG3397	chitin binding
EXW38_RS12630	COG0823	Involved in the tonB-independent uptake of proteins
EXW38_RS12640	COG1408	metallophosphoesterase
EXW38_RS12650	COG1131	(ABC) transporter
EXW38_RS12660	COG1309	transcriptional regulator
EXW38_RS12665	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS12670	COG0439	Biotin carboxylase
EXW38_RS12675	COG0511	ligase activity, forming carbon-carbon bonds
EXW38_RS12680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_RS12685	COG1024	Enoyl-CoA hydratase
EXW38_RS12690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW38_RS12695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_RS12750	COG1686	Belongs to the peptidase S11 family
EXW38_RS12785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_RS12810	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW38_RS12840	COG1733	regulation of RNA biosynthetic process
EXW38_RS12845	COG2226	methyltransferase
EXW38_RS12855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_RS12885	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_RS12900	COG0697	spore germination
EXW38_RS12905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS12940	COG2323	membrane
EXW38_RS12945	COG2132	Multicopper oxidase
EXW38_RS12960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS12965	COG0697	spore germination
EXW38_RS12970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW38_RS12975	COG0201	protein transport
EXW38_RS12985	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS12990	COG3227	Zinc metalloprotease (Elastase)
EXW38_RS12995	COG1523	belongs to the glycosyl hydrolase 13 family
EXW38_RS13000	COG1073	alpha beta
EXW38_RS13010	COG0577	efflux transmembrane transporter activity
EXW38_RS13015	COG1136	(ABC) transporter
EXW38_RS13035	COG5002	protein histidine kinase activity
EXW38_RS13040	COG0745	RESPONSE REGULATOR receiver
EXW38_RS13045	COG1011	Hydrolase
EXW38_RS13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_RS13070	COG1183	phosphatidylcholine synthase activity
EXW38_RS13080	COG1132	(ABC) transporter
EXW38_RS13090	COG3961	Belongs to the TPP enzyme family
EXW38_RS13110	COG0322	excinuclease ABC activity
EXW38_RS13135	COG2318	DinB family
EXW38_RS13150	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW38_RS13170	COG3878	Protein conserved in bacteria
EXW38_RS13180	COG0406	alpha-ribazole phosphatase activity
EXW38_RS13200	COG1051	belongs to the nudix hydrolase family
EXW38_RS13205	COG0592	DNA-directed DNA polymerase activity
EXW38_RS13220	COG2223	nitrite transmembrane transporter activity
EXW38_RS13230	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_RS13240	COG0494	nUDIX hydrolase
EXW38_RS13270	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_RS13285	COG2814	Major facilitator Superfamily
EXW38_RS13325	COG0768	penicillin binding
EXW38_RS13330	COG0671	phosphoesterase, PA-phosphatase related
EXW38_RS13335	COG0604	alcohol dehydrogenase
EXW38_RS13340	COG5002	protein histidine kinase activity
EXW38_RS13345	COG0745	RESPONSE REGULATOR receiver
EXW38_RS13355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_RS13365	COG2205	protein histidine kinase activity
EXW38_RS13380	COG1122	ATPase activity
EXW38_RS13385	COG4720	Psort location CytoplasmicMembrane, score
EXW38_RS13390	COG1794	racemase activity, acting on amino acids and derivatives
EXW38_RS13395	COG1819	glycosyl
EXW38_RS13405	COG0768	penicillin binding
EXW38_RS13410	COG5002	protein histidine kinase activity
EXW38_RS13415	COG0561	phosphatase activity
EXW38_RS13445	COG2124	cytochrome p450
EXW38_RS13475	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW38_RS13485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS13490	COG0460	homoserine dehydrogenase
EXW38_RS13510	COG0577	efflux transmembrane transporter activity
EXW38_RS13515	COG1136	(ABC) transporter
EXW38_RS13530	COG0488	(ABC) transporter
EXW38_RS13535	COG0667	Aldo Keto reductase
EXW38_RS13540	COG0583	DNA-binding transcription factor activity
EXW38_RS13545	COG2205	protein histidine kinase activity
EXW38_RS13550	COG0745	RESPONSE REGULATOR receiver
EXW38_RS13560	COG3773	Cell wall hydrolase
EXW38_RS13565	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW38_RS13605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS13620	COG2959	enzyme of heme biosynthesis
EXW38_RS13645	COG3483	tryptophan 2,3-dioxygenase activity
EXW38_RS13655	COG3844	kynureninase activity
EXW38_RS13660	COG1309	transcriptional regulator
EXW38_RS13680	COG1349	DNA-binding transcription factor activity
EXW38_RS13705	COG2223	nitrite transmembrane transporter activity
EXW38_RS13715	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS13750	COG4176	ABC-type proline glycine betaine transport system permease component
EXW38_RS13755	COG0517	IMP dehydrogenase activity
EXW38_RS13755	COG4175	Glycine betaine
EXW38_RS13780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW38_RS13785	COG2153	protein acetylation
EXW38_RS13790	COG1819	glycosyl
EXW38_RS13810	COG2205	protein histidine kinase activity
EXW38_RS13815	COG2315	Protein conserved in bacteria
EXW38_RS13860	COG3973	AAA domain
EXW38_RS13880	COG0514	ATP-dependent DNA helicase (RecQ)
EXW38_RS13905	COG4637	Psort location Cytoplasmic, score
EXW38_RS13925	COG1227	inorganic diphosphatase activity
EXW38_RS13930	COG2318	DinB family
EXW38_RS13945	COG1162	GTPase activity
EXW38_RS13950	COG1115	amino acid carrier protein
EXW38_RS13955	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS13960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW38_RS13970	COG3938	Belongs to the proline racemase family
EXW38_RS13975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_RS14020	COG1078	dGTPase activity
EXW38_RS14025	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS14040	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW38_RS14045	COG4166	transmembrane transport
EXW38_RS14055	COG4948	Mandelate Racemase Muconate Lactonizing
EXW38_RS14075	COG0667	Aldo Keto reductase
EXW38_RS14125	COG2936	dipeptidyl-peptidase activity
EXW38_RS14135	COG0745	RESPONSE REGULATOR receiver
EXW38_RS14165	COG1164	Oligoendopeptidase f
EXW38_RS14190	COG1307	EDD domain protein, DegV family
EXW38_RS14225	COG2814	Major facilitator Superfamily
EXW38_RS14235	COG1664	Polymer-forming cytoskeletal
EXW38_RS14240	COG0789	Transcriptional regulator
EXW38_RS14245	COG4533	DNA binding
EXW38_RS14250	COG2814	Major facilitator Superfamily
EXW38_RS14250	COG0477	Major facilitator Superfamily
EXW38_RS14265	COG2261	transglycosylase associated protein
EXW38_RS14280	COG2226	methyltransferase
EXW38_RS14315	COG0436	Aminotransferase
EXW38_RS14320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW38_RS14330	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW38_RS14345	COG1131	(ABC) transporter
EXW38_RS14395	COG0628	permease
EXW38_RS14420	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW38_RS14425	COG2720	vancomycin resistance protein
EXW38_RS14445	COG0697	spore germination
EXW38_RS14465	COG4912	Dna alkylation repair
EXW38_RS14500	COG2814	Major facilitator Superfamily
EXW38_RS14505	COG1368	sulfuric ester hydrolase activity
EXW38_RS14510	COG0488	(ABC) transporter
EXW38_RS14515	COG1033	growth of symbiont in host cell
EXW38_RS14515	COG2409	Drug exporters of the RND superfamily
EXW38_RS14520	COG1309	transcriptional regulator
EXW38_RS14535	COG0287	Prephenate dehydrogenase
EXW38_RS14550	COG1605	Chorismate mutase
EXW38_RS14550	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW38_RS14585	COG3584	3D domain protein
EXW38_RS14585	COG1388	LysM domain
EXW38_RS14595	COG0346	lactoylglutathione lyase activity
EXW38_RS14605	COG0277	FAD linked oxidase domain protein
EXW38_RS14625	COG2610	gluconate transmembrane transporter activity
EXW38_RS14630	COG1024	Enoyl-CoA hydratase
EXW38_RS14640	COG3290	protein histidine kinase activity
EXW38_RS14640	COG3829	transcription factor binding
EXW38_RS14650	COG0579	oxidoreductase
EXW38_RS14655	COG1879	ABC-type sugar transport system periplasmic component
EXW38_RS14665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW38_RS14675	COG2390	Transcriptional regulator
EXW38_RS14680	COG1070	Carbohydrate kinase
EXW38_RS14695	COG2226	methyltransferase
EXW38_RS14720	COG0346	lactoylglutathione lyase activity
EXW38_RS14725	COG2329	Antibiotic biosynthesis monooxygenase
EXW38_RS14745	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW38_RS14750	COG2207	Transcriptional regulator
EXW38_RS14755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS14760	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW38_RS14765	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW38_RS14770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_RS14775	COG3239	Fatty acid desaturase
EXW38_RS14790	COG3842	ATPase activity
EXW38_RS14815	COG1175	transmembrane transport
EXW38_RS14820	COG1349	DNA-binding transcription factor activity
EXW38_RS14830	COG3655	Transcriptional regulator
EXW38_RS14850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS14855	COG0346	lactoylglutathione lyase activity
EXW38_RS14885	COG0714	Associated with various cellular activities
EXW38_RS14905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW38_RS14910	COG0753	catalase activity
EXW38_RS14950	COG0714	Associated with various cellular activities
EXW38_RS14960	COG0778	Nitroreductase
EXW38_RS14965	COG1846	Transcriptional regulator
EXW38_RS14985	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW38_RS15005	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS15010	COG0183	Belongs to the thiolase family
EXW38_RS15015	COG1024	Enoyl-CoA hydratase
EXW38_RS15020	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_RS15025	COG2723	6-phospho-beta-galactosidase activity
EXW38_RS15030	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_RS15035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS15050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS15060	COG2508	Transcriptional regulator
EXW38_RS15065	COG2814	Major facilitator Superfamily
EXW38_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS15100	COG1309	transcriptional regulator
EXW38_RS15120	COG2207	Transcriptional regulator
EXW38_RS15125	COG0456	acetyltransferase
EXW38_RS15140	COG0697	spore germination
EXW38_RS15145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS15165	COG0642	Histidine kinase
EXW38_RS15170	COG0745	RESPONSE REGULATOR receiver
EXW38_RS15175	COG0596	Alpha beta hydrolase
EXW38_RS15185	COG0456	acetyltransferase
EXW38_RS15185	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_RS15210	COG0730	response to heat
EXW38_RS15220	COG0833	amino acid
EXW38_RS15230	COG4335	DNA alkylation repair
EXW38_RS15255	COG0768	penicillin binding
EXW38_RS15270	COG3104	oligopeptide transport
EXW38_RS15275	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW38_RS15290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW38_RS15295	COG1984	allophanate hydrolase subunit 2
EXW38_RS15300	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW38_RS15305	COG1414	Transcriptional regulator
EXW38_RS15325	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS15370	COG0574	Belongs to the PEP-utilizing enzyme family
EXW38_RS15370	COG3848	Pyruvate phosphate dikinase
EXW38_RS15420	COG0798	PFAM Bile acid sodium symporter
EXW38_RS15425	COG0346	lactoylglutathione lyase activity
EXW38_RS15430	COG0640	Transcriptional regulator
EXW38_RS15445	COG1309	transcriptional regulator
EXW38_RS15450	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS15455	COG1522	sequence-specific DNA binding
EXW38_RS15470	COG0346	lactoylglutathione lyase activity
EXW38_RS15485	COG0457	Tetratricopeptide repeat
EXW38_RS15500	COG0745	RESPONSE REGULATOR receiver
EXW38_RS15505	COG3850	Histidine kinase
EXW38_RS15505	COG5002	protein histidine kinase activity
EXW38_RS15545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW38_RS15550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW38_RS15565	COG2226	methyltransferase
EXW38_RS15580	COG1690	Belongs to the RtcB family
EXW38_RS15590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW38_RS15605	COG1136	(ABC) transporter
EXW38_RS15610	COG0577	efflux transmembrane transporter activity
EXW38_RS15630	COG5002	protein histidine kinase activity
EXW38_RS15630	COG3850	Histidine kinase
EXW38_RS15645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS15650	COG2271	Major facilitator Superfamily
EXW38_RS15655	COG1556	Lactate utilization protein
EXW38_RS15660	COG1139	Iron-sulfur cluster binding protein
EXW38_RS15670	COG0583	DNA-binding transcription factor activity
EXW38_RS15675	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_RS15690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW38_RS15710	COG1595	DNA-templated transcription, initiation
EXW38_RS15740	COG2814	Major facilitator Superfamily
EXW38_RS15770	COG1876	peptidase activity
EXW38_RS15775	COG2843	Capsule synthesis protein
EXW38_RS15790	COG0477	Major facilitator Superfamily
EXW38_RS15805	COG1846	Transcriptional regulator
EXW38_RS15810	COG2814	Major facilitator Superfamily
EXW38_RS16010	COG4187	Peptidase family M20/M25/M40
EXW38_RS16015	COG1414	Transcriptional regulator
EXW38_RS16020	COG0833	amino acid
EXW38_RS16040	COG2031	fatty acid transporter
EXW38_RS16050	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS16110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW38_RS16115	COG2356	endonuclease I
EXW38_RS16120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_RS16130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW38_RS16150	COG1785	Belongs to the alkaline phosphatase family
EXW38_RS16165	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS16175	COG1131	(ABC) transporter
EXW38_RS16200	COG1011	Hydrolase
EXW38_RS16205	COG2365	Tyrosine phosphatase family
EXW38_RS16235	COG0628	permease
EXW38_RS16270	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW38_RS16280	COG1253	flavin adenine dinucleotide binding
EXW38_RS16285	COG0789	Transcriptional regulator
EXW38_RS16290	COG0697	spore germination
EXW38_RS16295	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW38_RS16300	COG3813	Protein conserved in bacteria
EXW38_RS16305	COG4702	Belongs to the UPF0303 family
EXW38_RS16315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS16325	COG0494	nUDIX hydrolase
EXW38_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS16355	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS16360	COG1733	regulation of RNA biosynthetic process
EXW38_RS16365	COG0640	Transcriptional regulator
EXW38_RS16385	COG1191	sigma factor activity
EXW38_RS16410	COG5002	protein histidine kinase activity
EXW38_RS16435	COG0657	acetylesterase activity
EXW38_RS16445	COG2814	Major facilitator Superfamily
EXW38_RS16450	COG1309	transcriptional regulator
EXW38_RS16465	COG2224	Isocitrate lyase
EXW38_RS16500	COG0814	amino acid
EXW38_RS16525	COG1151	hydroxylamine reductase activity
EXW38_RS16530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS16555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_RS16565	COG2072	flavoprotein involved in K transport
EXW38_RS16610	COG0714	Associated with various cellular activities
EXW38_RS16665	COG1695	Transcriptional regulator
EXW38_RS16670	COG0604	alcohol dehydrogenase
EXW38_RS16675	COG1113	amino acid transport
EXW38_RS16680	COG0456	acetyltransferase
EXW38_RS16695	COG5002	protein histidine kinase activity
EXW38_RS16700	COG0745	RESPONSE REGULATOR receiver
EXW38_RS16705	COG5002	protein histidine kinase activity
EXW38_RS16710	COG2814	Major facilitator Superfamily
EXW38_RS16720	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_RS16725	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS16735	COG0534	Mate efflux family protein
EXW38_RS16740	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS16745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW38_RS16760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_RS16765	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_RS16780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS16785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS16790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS16795	COG3739	integral membrane protein
EXW38_RS16830	COG1193	negative regulation of DNA recombination
EXW38_RS16840	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW38_RS16845	COG1164	Oligoendopeptidase f
EXW38_RS16870	COG3781	membrane
EXW38_RS16885	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_RS16965	COG0640	Transcriptional regulator
EXW38_RS16970	COG0604	alcohol dehydrogenase
EXW38_RS16975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW38_RS17000	COG2808	Putative FMN-binding domain
EXW38_RS17005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_RS17015	COG0277	FAD linked oxidase domain protein
EXW38_RS17035	COG1285	pathogenesis
EXW38_RS17045	COG2514	catechol 2,3-dioxygenase activity
EXW38_RS17050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS17055	COG1126	abc transporter atp-binding protein
EXW38_RS17060	COG0765	amino acid transport
EXW38_RS17065	COG2720	vancomycin resistance protein
EXW38_RS17090	COG1278	Cold shock
EXW38_RS17100	COG0716	FMN binding
EXW38_RS17130	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS17140	COG0165	Argininosuccinate lyase
EXW38_RS17155	COG4145	pantothenate transmembrane transporter activity
EXW38_RS17165	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS17180	COG1657	PFAM Prenyltransferase squalene oxidase
EXW38_RS17185	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW38_RS17190	COG2962	Rard protein
EXW38_RS17195	COG3326	Membrane
EXW38_RS17200	COG0531	amino acid
EXW38_RS17225	COG1737	Transcriptional regulator
EXW38_RS17230	COG2971	BadF BadG BcrA BcrD
EXW38_RS17240	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_RS17245	COG1486	melibiose metabolic process
EXW38_RS17255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS17280	COG2226	methyltransferase
EXW38_RS17285	COG4166	transmembrane transport
EXW38_RS17290	COG4166	transmembrane transport
EXW38_RS17295	COG4166	transmembrane transport
EXW38_RS17300	COG1316	TRANSCRIPTIONal
EXW38_RS17315	COG1131	(ABC) transporter
EXW38_RS17325	COG0673	inositol 2-dehydrogenase activity
EXW38_RS17330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW38_RS17335	COG0187	DNA topoisomerase II activity
EXW38_RS17340	COG1832	CoA-binding protein
EXW38_RS17345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_RS17350	COG0745	RESPONSE REGULATOR receiver
EXW38_RS17360	COG1328	CTP reductase activity
EXW38_RS17370	COG4841	protein insertion into membrane
EXW38_RS17375	COG0824	Thioesterase
EXW38_RS17400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_RS17415	COG1132	(ABC) transporter
EXW38_RS17420	COG1266	CAAX protease self-immunity
EXW38_RS17425	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW38_RS17455	COG2211	Major facilitator Superfamily
EXW38_RS17465	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW38_RS17480	COG0183	Belongs to the thiolase family
EXW38_RS17485	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS17490	COG1268	BioY protein
EXW38_RS17495	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS17500	COG1396	sequence-specific DNA binding
EXW38_RS17535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS17545	COG5002	protein histidine kinase activity
EXW38_RS17555	COG0400	carboxylic ester hydrolase activity
EXW38_RS17565	COG0069	glutamate synthase activity
EXW38_RS17570	COG1902	pentaerythritol trinitrate reductase activity
EXW38_RS17575	COG1329	Transcriptional regulator
EXW38_RS17580	COG0010	Belongs to the arginase family
EXW38_RS17590	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW38_RS17595	COG2986	histidine ammonia-lyase
EXW38_RS17605	COG2226	methyltransferase
EXW38_RS17630	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW38_RS17635	COG0785	Cytochrome C biogenesis protein
EXW38_RS17645	COG1473	amidohydrolase
EXW38_RS17650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_RS17655	COG1131	(ABC) transporter
EXW38_RS17670	COG0583	DNA-binding transcription factor activity
EXW38_RS17680	COG1346	cytolysis
EXW38_RS17695	COG0730	response to heat
EXW38_RS17720	COG1132	(ABC) transporter
EXW38_RS17725	COG1132	(ABC) transporter
EXW38_RS17730	COG3763	UPF0154 protein
EXW38_RS17745	COG3639	organic phosphonate transmembrane transporter activity
EXW38_RS17750	COG3639	organic phosphonate transmembrane transporter activity
EXW38_RS17760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS17765	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS17775	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_RS17780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW38_RS17795	COG1695	Transcriptional regulator
EXW38_RS17800	COG1132	(ABC) transporter
EXW38_RS17830	COG0367	asparagine synthase
EXW38_RS17835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW38_RS17845	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW38_RS17850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW38_RS17860	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW38_RS17860	COG3420	alginic acid biosynthetic process
EXW38_RS17865	COG1442	glycosyl transferase family 8
EXW38_RS17865	COG1216	Glycosyl transferase, family 2
EXW38_RS17890	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS17900	COG1215	transferase activity, transferring glycosyl groups
EXW38_RS17905	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS17910	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS17915	COG1086	Polysaccharide biosynthesis protein
EXW38_RS17920	COG0489	protein tyrosine kinase activity
EXW38_RS17930	COG0174	glutamine synthetase
EXW38_RS17935	COG0789	Transcriptional regulator
EXW38_RS17940	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW38_RS17945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW38_RS17950	COG2860	membrane
EXW38_RS17960	COG0464	growth
EXW38_RS17980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW38_RS17990	COG1388	LysM domain
EXW38_RS17990	COG3584	3D domain protein
EXW38_RS17995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW38_RS17995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_RS17995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW38_RS18000	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW38_RS18005	COG1349	DNA-binding transcription factor activity
EXW38_RS18010	COG1979	alcohol dehydrogenase
EXW38_RS18015	COG2322	membrane
EXW38_RS18025	COG1473	amidohydrolase
EXW38_RS18030	COG1408	metallophosphoesterase
EXW38_RS18045	COG2217	Heavy metal translocating P-type atpase
EXW38_RS18050	COG2608	mercury ion transmembrane transporter activity
EXW38_RS18055	COG1937	Protein conserved in bacteria
EXW38_RS18085	COG2819	hydrolase of the alpha beta superfamily
EXW38_RS18090	COG1120	ATPase activity
EXW38_RS18095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS18100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS18105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS18110	COG0708	Exodeoxyribonuclease III
EXW38_RS18115	COG2169	Transcriptional regulator
EXW38_RS18120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW38_RS18125	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW38_RS18130	COG2706	6-phosphogluconolactonase activity
EXW38_RS18135	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_RS18140	COG2364	Membrane
EXW38_RS18155	COG0346	lactoylglutathione lyase activity
EXW38_RS18160	COG3300	MHYT domain
EXW38_RS18160	COG5001	Diguanylate cyclase
EXW38_RS18195	COG1346	cytolysis
EXW38_RS18205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW38_RS18210	COG2945	thiolester hydrolase activity
EXW38_RS18210	COG0596	Alpha beta hydrolase
EXW38_RS18215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW38_RS18225	COG2188	Transcriptional regulator
EXW38_RS18230	COG2723	6-phospho-beta-galactosidase activity
EXW38_RS18240	COG3773	Cell wall hydrolase
EXW38_RS18250	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW38_RS18260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW38_RS18265	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW38_RS18275	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW38_RS18280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW38_RS18285	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW38_RS18290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW38_RS18290	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW38_RS18300	COG2359	stage V sporulation protein S
EXW38_RS18305	COG1692	metallophosphoesterase
EXW38_RS18310	COG1418	mRNA catabolic process
EXW38_RS18315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW38_RS18320	COG1058	Belongs to the CinA family
EXW38_RS18320	COG1546	Belongs to the CinA family
EXW38_RS18325	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW38_RS18330	COG1426	Protein conserved in bacteria
EXW38_RS18345	COG0300	oxidoreductase activity
EXW38_RS18350	COG0612	Peptidase, M16
EXW38_RS18355	COG0612	Peptidase, M16
EXW38_RS18360	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW38_RS18365	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW38_RS18370	COG3845	ABC transporter
EXW38_RS18375	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW38_RS18380	COG2188	Transcriptional regulator
EXW38_RS18390	COG1674	ftsk spoiiie
EXW38_RS18400	COG0740	serine-type endopeptidase activity
EXW38_RS18405	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_RS18415	COG0527	aspartate kinase activity
EXW38_RS18420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW38_RS18540	COG0740	serine-type endopeptidase activity
EXW38_RS18585	COG0582	viral genome integration into host DNA
EXW38_RS18625	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_RS18660	COG3620	sequence-specific DNA binding
EXW38_RS18685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW38_RS18690	COG1873	PFAM PRC-barrel domain
EXW38_RS18695	COG0612	Peptidase, M16
EXW38_RS18700	COG0726	polysaccharide deacetylase
EXW38_RS18705	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW38_RS18715	COG0196	riboflavin kinase activity
EXW38_RS18725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW38_RS18730	COG1550	Protein conserved in bacteria
EXW38_RS18735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW38_RS18740	COG1358	cellular component organization or biogenesis
EXW38_RS18745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW38_RS18750	COG0195	Participates in both transcription termination and antitermination
EXW38_RS18765	COG0442	prolyl-tRNA aminoacylation
EXW38_RS18770	COG0750	zinc metalloprotease
EXW38_RS18780	COG4589	Belongs to the CDS family
EXW38_RS18790	COG0233	cytoplasmic translational termination
EXW38_RS18795	COG0528	UMP kinase activity
EXW38_RS18800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW38_RS18805	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW38_RS18810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW38_RS18815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW38_RS18820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW38_RS18825	COG4974	Belongs to the 'phage' integrase family
EXW38_RS18830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW38_RS18835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW38_RS18840	COG0758	DNA mediated transformation
EXW38_RS18845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW38_RS18850	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW38_RS18855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW38_RS18870	COG0335	large ribosomal subunit rRNA binding
EXW38_RS18875	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW38_RS18880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW38_RS18885	COG1837	Belongs to the UPF0109 family
EXW38_RS18895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW38_RS18905	COG0552	protein localization to endoplasmic reticulum
EXW38_RS18910	COG1196	nuclear chromosome segregation
EXW38_RS18915	COG0571	ribonuclease III activity
EXW38_RS18920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW38_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS18930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW38_RS18935	COG0416	fatty acid biosynthetic process
EXW38_RS18945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW38_RS18950	COG1461	Dihydroxyacetone kinase
EXW38_RS18955	COG1302	Protein conserved in bacteria
EXW38_RS18970	COG1564	THIamine pyrophosphokinase
EXW38_RS18975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW38_RS18985	COG0515	serine threonine protein kinase
EXW38_RS18985	COG2815	serine threonine protein kinase
EXW38_RS18990	COG0631	protein serine/threonine phosphatase activity
EXW38_RS18995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW38_RS19000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW38_RS19000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW38_RS19005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW38_RS19010	COG0242	peptide deformylase activity
EXW38_RS19015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW38_RS19020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW38_RS19025	COG1758	RNA polymerase activity
EXW38_RS19040	COG1561	YicC-like family, N-terminal region
EXW38_RS19045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW38_RS19060	COG0006	proline dipeptidase activity
EXW38_RS19075	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW38_RS19100	COG0167	dihydroorotate dehydrogenase activity
EXW38_RS19105	COG0543	2 iron, 2 sulfur cluster binding
EXW38_RS19110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW38_RS19120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW38_RS19125	COG0540	Belongs to the ATCase OTCase family
EXW38_RS19135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW38_RS19140	COG0564	pseudouridine synthase activity
EXW38_RS19160	COG3599	regulation of cell shape
EXW38_RS19165	COG2302	S4 RNA-binding domain
EXW38_RS19170	COG0762	integral membrane protein
EXW38_RS19175	COG1799	cell septum assembly
EXW38_RS19180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW38_RS19190	COG1873	PFAM PRC-barrel domain
EXW38_RS19195	COG1191	sigma factor activity
EXW38_RS19200	COG1191	sigma factor activity
EXW38_RS19210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW38_RS19215	COG0849	cell division
EXW38_RS19220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW38_RS19235	COG0772	Belongs to the SEDS family
EXW38_RS19240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW38_RS19245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW38_RS19250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW38_RS19255	COG0768	penicillin binding
EXW38_RS19260	COG0768	penicillin binding
EXW38_RS19270	COG0275	rRNA processing
EXW38_RS19275	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW38_RS19280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW38_RS19285	COG0454	-acetyltransferase
EXW38_RS19295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW38_RS19300	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW38_RS19305	COG1323	Belongs to the UPF0348 family
EXW38_RS19310	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW38_RS19315	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW38_RS19320	COG3314	Sporulation integral membrane protein YlbJ
EXW38_RS19330	COG0742	ribosomal rna small subunit methyltransferase
EXW38_RS19340	COG4471	UPF0298 protein
EXW38_RS19345	COG3679	Belongs to the UPF0342 family
EXW38_RS19350	COG0406	alpha-ribazole phosphatase activity
EXW38_RS19365	COG2340	Cysteine-rich secretory protein family
EXW38_RS19375	COG3336	cytochrome c oxidase
EXW38_RS19390	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW38_RS19400	COG0109	protoheme IX farnesyltransferase activity
EXW38_RS19405	COG1612	heme a metabolic process
EXW38_RS19410	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW38_RS19415	COG0772	Belongs to the SEDS family
EXW38_RS19420	COG4838	Belongs to the UPF0358 family
EXW38_RS19425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW38_RS19430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW38_RS19440	COG4896	Protein conserved in bacteria
EXW38_RS19455	COG1217	gtp-binding protein TYPA
EXW38_RS19465	COG0483	inositol monophosphate 1-phosphatase activity
EXW38_RS19475	COG4493	Belongs to the UPF0637 family
EXW38_RS19480	COG4476	Belongs to the UPF0223 family
EXW38_RS19485	COG1982	Orn Lys Arg decarboxylase major
EXW38_RS19535	COG0022	dehydrogenase e1 component
EXW38_RS19540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW38_RS19555	COG0561	phosphatase activity
EXW38_RS19560	COG5503	Protein of unknown function (DUF1447)
EXW38_RS19565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_RS19570	COG0569	domain protein
EXW38_RS19580	COG1473	amidohydrolase
EXW38_RS19585	COG2171	N-acyltransferase activity
EXW38_RS19590	COG0583	DNA-binding transcription factor activity
EXW38_RS19595	COG0517	IMP dehydrogenase activity
EXW38_RS19605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW38_RS19615	COG4703	Protein of unknown function (DUF1797)
EXW38_RS19630	COG2200	EAL domain
EXW38_RS19635	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS19640	COG1408	metallophosphoesterase
EXW38_RS19685	COG2814	Major facilitator Superfamily
EXW38_RS19695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW38_RS19705	COG3209	COG3209 Rhs family protein
EXW38_RS19715	COG2205	protein histidine kinase activity
EXW38_RS19725	COG0436	Aminotransferase
EXW38_RS19730	COG1609	Transcriptional regulator
EXW38_RS19735	COG3833	ABC-type maltose transport systems, permease component
EXW38_RS19740	COG1175	transmembrane transport
EXW38_RS19745	COG2182	Extracellular solute-binding protein
EXW38_RS19755	COG0366	Alpha amylase catalytic
EXW38_RS19760	COG3842	ATPase activity
EXW38_RS19805	COG0183	Belongs to the thiolase family
EXW38_RS19840	COG1695	Transcriptional regulator
EXW38_RS19845	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS19855	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW38_RS19865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW38_RS19870	COG0436	Aminotransferase
EXW38_RS19875	COG1850	ribulose-bisphosphate carboxylase activity
EXW38_RS19880	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW38_RS19885	COG0235	Class ii aldolase
EXW38_RS19890	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW38_RS19905	COG2084	Dehydrogenase
EXW38_RS19915	COG2199	diguanylate cyclase activity
EXW38_RS19920	COG0778	Nitroreductase
EXW38_RS19945	COG1263	PTS System
EXW38_RS19945	COG2190	(PTS) system
EXW38_RS19945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS19950	COG3711	transcriptional antiterminator
EXW38_RS19960	COG2188	Transcriptional regulator
EXW38_RS19965	COG0363	glucosamine-6-phosphate deaminase activity
EXW38_RS19970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW38_RS19980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW38_RS19985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW38_RS19995	COG1547	Domain of unknown function (DUF309)
EXW38_RS20005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW38_RS20010	COG4086	secreted protein
EXW38_RS20015	COG0561	phosphatase activity
EXW38_RS20020	COG0697	spore germination
EXW38_RS20035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_RS20075	COG1686	Belongs to the peptidase S11 family
EXW38_RS20080	COG1725	Transcriptional regulator
EXW38_RS20085	COG1131	(ABC) transporter
EXW38_RS20105	COG1846	Transcriptional regulator
EXW38_RS20120	COG0598	Magnesium transport protein CorA
EXW38_RS20135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW38_RS20145	COG4974	Belongs to the 'phage' integrase family
EXW38_RS20155	COG0735	belongs to the Fur family
EXW38_RS20160	COG1300	Membrane
EXW38_RS20180	COG0667	Aldo Keto reductase
EXW38_RS20185	COG0656	L-ascorbic acid biosynthetic process
EXW38_RS20190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW38_RS20190	COG0456	acetyltransferase
EXW38_RS20200	COG1525	nuclease
EXW38_RS20200	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS20200	COG4085	toxin activity
EXW38_RS20205	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW38_RS20215	COG0596	Alpha beta hydrolase
EXW38_RS20220	COG2056	Na+-H+ antiporter family
EXW38_RS20225	COG1609	Transcriptional regulator
EXW38_RS20230	COG0456	acetyltransferase
EXW38_RS20235	COG1073	alpha beta
EXW38_RS20250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW38_RS20250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW38_RS20255	COG0307	riboflavin synthase, alpha
EXW38_RS20260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW38_RS20260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW38_RS20275	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW38_RS20285	COG1073	alpha beta
EXW38_RS20285	COG2226	methyltransferase
EXW38_RS20290	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_RS20300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_RS20310	COG1757	Na H antiporter
EXW38_RS20315	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS20325	COG1522	sequence-specific DNA binding
EXW38_RS20355	COG5444	nuclease activity
EXW38_RS20365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW38_RS20370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW38_RS20380	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW38_RS20390	COG0300	oxidoreductase activity
EXW38_RS20395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS20400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_RS20405	COG1760	l-serine dehydratase
EXW38_RS20410	COG1760	l-serine dehydratase
EXW38_RS20420	COG1234	tRNA 3'-trailer cleavage
EXW38_RS20450	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW38_RS20455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS20470	COG1376	ErfK ybiS ycfS ynhG family protein
EXW38_RS20475	COG4129	membrane
EXW38_RS20480	COG1126	abc transporter atp-binding protein
EXW38_RS20485	COG0765	amino acid transport
EXW38_RS20490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW38_RS20500	COG2816	NAD+ diphosphatase activity
EXW38_RS20505	COG2323	membrane
EXW38_RS20510	COG0772	Belongs to the SEDS family
EXW38_RS20515	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW38_RS20520	COG0022	dehydrogenase e1 component
EXW38_RS20525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW38_RS20530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW38_RS20535	COG3426	butyrate kinase activity
EXW38_RS20545	COG0280	phosphate acetyltransferase
EXW38_RS20550	COG3290	protein histidine kinase activity
EXW38_RS20550	COG3829	transcription factor binding
EXW38_RS20560	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_RS20565	COG3093	addiction module antidote protein HigA
EXW38_RS20575	COG0745	RESPONSE REGULATOR receiver
EXW38_RS20580	COG0750	zinc metalloprotease
EXW38_RS20585	COG0497	DNA recombination
EXW38_RS20590	COG1438	arginine binding
EXW38_RS20595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW38_RS20600	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW38_RS20605	COG0142	geranyltranstransferase activity
EXW38_RS20610	COG1722	exodeoxyribonuclease VII activity
EXW38_RS20620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW38_RS20625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW38_RS20630	COG1302	Protein conserved in bacteria
EXW38_RS20635	COG0439	Biotin carboxylase
EXW38_RS20640	COG0511	ligase activity, forming carbon-carbon bonds
EXW38_RS20685	COG3854	ATPases associated with a variety of cellular activities
EXW38_RS20705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW38_RS20710	COG0006	proline dipeptidase activity
EXW38_RS20725	COG3872	metal-dependent enzyme
EXW38_RS20735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW38_RS20770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_RS20780	COG1609	Transcriptional regulator
EXW38_RS20790	COG2076	Multidrug Resistance protein
EXW38_RS20795	COG2076	Multidrug Resistance protein
EXW38_RS20835	COG1725	Transcriptional regulator
EXW38_RS20850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW38_RS20855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW38_RS20860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW38_RS20865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_RS20895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW38_RS20920	COG4970	Tfp pilus assembly protein FimT
EXW38_RS20925	COG4537	Required for transformation and DNA binding
EXW38_RS20930	COG1459	type II secretion system
EXW38_RS20935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW38_RS21010	COG1410	methionine synthase
EXW38_RS21010	COG0646	methionine synthase
EXW38_RS21015	COG0646	methionine synthase
EXW38_RS21015	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW38_RS21020	COG0626	cystathionine gamma-synthase activity
EXW38_RS21025	COG0626	cystathionine gamma-synthase activity
EXW38_RS21045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS21055	COG1940	carbohydrate kinase activity
EXW38_RS21060	COG4483	Protein conserved in bacteria
EXW38_RS21065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW38_RS21070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW38_RS21075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW38_RS21080	COG0704	Plays a role in the regulation of phosphate uptake
EXW38_RS21090	COG0581	inorganic phosphate transmembrane transporter activity
EXW38_RS21095	COG0573	inorganic phosphate transmembrane transporter activity
EXW38_RS21100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW38_RS21105	COG0768	penicillin binding
EXW38_RS21110	COG0477	Major facilitator Superfamily
EXW38_RS21115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW38_RS21130	COG1388	LysM domain
EXW38_RS21135	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW38_RS21140	COG0735	belongs to the Fur family
EXW38_RS21145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW38_RS21150	COG1121	(ABC) transporter
EXW38_RS21155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS21165	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW38_RS21185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW38_RS21190	COG2384	SAM-dependent methyltransferase
EXW38_RS21195	COG2010	Cytochrome c
EXW38_RS21200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW38_RS21205	COG0358	DNA primase activity
EXW38_RS21215	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW38_RS21220	COG0517	IMP dehydrogenase activity
EXW38_RS21225	COG1381	Involved in DNA repair and RecF pathway recombination
EXW38_RS21235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW38_RS21240	COG0295	cytidine deaminase activity
EXW38_RS21245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW38_RS21250	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW38_RS21255	COG1480	7TM receptor with intracellular HD hydrolase
EXW38_RS21260	COG1702	phosphate starvation-inducible protein PhoH
EXW38_RS21275	COG1610	YqeY-like protein
EXW38_RS21280	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW38_RS21285	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW38_RS21290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW38_RS21300	COG0484	heat shock protein binding
EXW38_RS21305	COG0443	Heat shock 70 kDa protein
EXW38_RS21315	COG1420	regulation of RNA biosynthetic process
EXW38_RS21320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW38_RS21325	COG1733	regulation of RNA biosynthetic process
EXW38_RS21330	COG0481	GTPase activity
EXW38_RS21340	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW38_RS21345	COG0268	Binds directly to 16S ribosomal RNA
EXW38_RS21350	COG1466	dna polymerase III delta subunit
EXW38_RS21360	COG0658	competence protein
EXW38_RS21360	COG2333	competence protein COMEC
EXW38_RS21365	COG2131	deaminase
EXW38_RS21375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW38_RS21380	COG2226	methyltransferase
EXW38_RS21385	COG0799	negative regulation of ribosome biogenesis
EXW38_RS21390	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW38_RS21395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW38_RS21400	COG1534	Rna-binding protein
EXW38_RS21405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW38_RS21410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW38_RS21415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW38_RS21425	COG0688	phosphatidylethanolamine metabolic process
EXW38_RS21445	COG2357	RelA SpoT domain protein
EXW38_RS21455	COG1785	Belongs to the alkaline phosphatase family
EXW38_RS21465	COG2267	carboxylic ester hydrolase activity
EXW38_RS21500	COG1404	Belongs to the peptidase S8 family
EXW38_RS21505	COG3186	Phenylalanine-4-hydroxylase
EXW38_RS21515	COG2514	catechol 2,3-dioxygenase activity
EXW38_RS21520	COG2259	Doxx family
EXW38_RS21560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW38_RS21570	COG1012	belongs to the aldehyde dehydrogenase family
EXW38_RS21570	COG1454	alcohol dehydrogenase
EXW38_RS21575	COG0626	cystathionine gamma-synthase activity
EXW38_RS21580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW38_RS21585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW38_RS21590	COG2226	methyltransferase
EXW38_RS21605	COG0768	penicillin binding
EXW38_RS21615	COG0572	uridine kinase
EXW38_RS21620	COG0826	peptidase U32
EXW38_RS21625	COG0826	peptidase U32
EXW38_RS21630	COG4122	O-methyltransferase activity
EXW38_RS21635	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW38_RS21645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW38_RS21655	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW38_RS21660	COG0628	permease
EXW38_RS21680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW38_RS21690	COG0482	sulfurtransferase activity
EXW38_RS21695	COG1104	cysteine desulfurase activity
EXW38_RS21700	COG1959	2 iron, 2 sulfur cluster binding
EXW38_RS21705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW38_RS21715	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW38_RS21720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW38_RS21735	COG1490	D-aminoacyl-tRNA deacylase activity
EXW38_RS21740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW38_RS21745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW38_RS21750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW38_RS21750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW38_RS21755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW38_RS21760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW38_RS21760	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW38_RS21770	COG2244	polysaccharide biosynthetic process
EXW38_RS21775	COG2323	membrane
EXW38_RS21785	COG1862	Preprotein translocase
EXW38_RS21790	COG0343	queuine tRNA-ribosyltransferase activity
EXW38_RS21805	COG2255	four-way junction helicase activity
EXW38_RS21810	COG0632	four-way junction helicase activity
EXW38_RS21815	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW38_RS21840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW38_RS21845	COG0157	Belongs to the NadC ModD family
EXW38_RS21850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW38_RS21855	COG1104	cysteine desulfurase activity
EXW38_RS21860	COG1827	regulation of RNA biosynthetic process
EXW38_RS21865	COG2258	MOSC domain
EXW38_RS21875	COG0077	Prephenate dehydratase
EXW38_RS21880	COG0577	efflux transmembrane transporter activity
EXW38_RS21885	COG0577	efflux transmembrane transporter activity
EXW38_RS21890	COG1136	(ABC) transporter
EXW38_RS21895	COG5002	protein histidine kinase activity
EXW38_RS21900	COG0745	RESPONSE REGULATOR receiver
EXW38_RS21905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW38_RS21910	COG3290	protein histidine kinase activity
EXW38_RS21920	COG2868	ribosomal protein
EXW38_RS21930	COG1530	ribonuclease E activity
EXW38_RS21935	COG1994	Peptidase M50
EXW38_RS21940	COG0739	heme binding
EXW38_RS21945	COG2894	cell division
EXW38_RS21950	COG0850	regulation of cytokinetic process
EXW38_RS21965	COG1077	Cell shape determining protein MreB Mrl
EXW38_RS21970	COG2003	Belongs to the UPF0758 family
EXW38_RS21975	COG0424	maF-like protein
EXW38_RS21985	COG0285	dihydrofolate synthase activity
EXW38_RS22000	COG1388	LysM domain
EXW38_RS22005	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW38_RS22010	COG0113	porphobilinogen synthase activity
EXW38_RS22015	COG1587	Uroporphyrinogen-III synthase
EXW38_RS22020	COG0181	hydroxymethylbilane synthase activity
EXW38_RS22025	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW38_RS22030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW38_RS22035	COG1846	Transcriptional regulator
EXW38_RS22040	COG1764	response to oxidative stress
EXW38_RS22045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW38_RS22055	COG0470	DNA polymerase III
EXW38_RS22055	COG1067	ATP-dependent peptidase activity
EXW38_RS22065	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW38_RS22095	COG0622	Phosphoesterase
EXW38_RS22105	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW38_RS22110	COG5401	PFAM Sporulation and spore germination
EXW38_RS22130	COG2197	response regulator
EXW38_RS22135	COG2233	PERMEase
EXW38_RS22140	COG0402	S-adenosylhomocysteine deaminase activity
EXW38_RS22145	COG1983	PspC domain protein
EXW38_RS22150	COG1396	sequence-specific DNA binding
EXW38_RS22155	COG0697	spore germination
EXW38_RS22165	COG1959	2 iron, 2 sulfur cluster binding
EXW38_RS22170	COG1668	transmembrane transport
EXW38_RS22175	COG4152	abc transporter atp-binding protein
EXW38_RS22180	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW38_RS22185	COG1360	Flagellar Motor Protein
EXW38_RS22190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW38_RS22195	COG1876	peptidase activity
EXW38_RS22200	COG0824	Thioesterase
EXW38_RS22205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW38_RS22210	COG1053	succinate dehydrogenase
EXW38_RS22215	COG2009	succinate dehydrogenase
EXW38_RS22220	COG1719	4-vinyl reductase, 4VR
EXW38_RS22225	COG0322	excinuclease ABC activity
EXW38_RS22230	COG3118	belongs to the thioredoxin family
EXW38_RS22235	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW38_RS22240	COG2086	electron transfer activity
EXW38_RS22245	COG1024	Enoyl-CoA hydratase
EXW38_RS22250	COG1309	transcriptional regulator
EXW38_RS22255	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS22280	COG2318	DinB family
EXW38_RS22310	COG1131	(ABC) transporter
EXW38_RS22315	COG2205	protein histidine kinase activity
EXW38_RS22320	COG0745	RESPONSE REGULATOR receiver
EXW38_RS22330	COG4895	conserved protein (DUF2196)
EXW38_RS22335	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW38_RS22345	COG4509	Sortase family
EXW38_RS22350	COG1120	ATPase activity
EXW38_RS22365	COG5386	Cell surface protein
EXW38_RS22370	COG5386	Cell surface protein
EXW38_RS22375	COG1114	Component of the transport system for branched-chain amino acids
EXW38_RS22380	COG1187	pseudouridine synthase activity
EXW38_RS22385	COG1193	negative regulation of DNA recombination
EXW38_RS22390	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW38_RS22390	COG1796	DNA polymerase
EXW38_RS22395	COG1286	toxin biosynthetic process
EXW38_RS22400	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW38_RS22405	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW38_RS22430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW38_RS22435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW38_RS22445	COG1418	mRNA catabolic process
EXW38_RS22465	COG2814	Major facilitator Superfamily
EXW38_RS22470	COG1566	PFAM secretion protein HlyD family protein
EXW38_RS22475	COG1309	transcriptional regulator
EXW38_RS22480	COG1363	Peptidase, m42
EXW38_RS22490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW38_RS22505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW38_RS22515	COG1484	DNA-dependent DNA replication
EXW38_RS22520	COG3611	Membrane attachment protein
EXW38_RS22525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW38_RS22530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW38_RS22535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW38_RS22545	COG1971	Probably functions as a manganese efflux pump
EXW38_RS22555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_RS22555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW38_RS22560	COG5002	protein histidine kinase activity
EXW38_RS22565	COG0745	RESPONSE REGULATOR receiver
EXW38_RS22585	COG0538	isocitrate dehydrogenase activity
EXW38_RS22590	COG0372	Belongs to the citrate synthase family
EXW38_RS22600	COG0628	permease
EXW38_RS22605	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW38_RS22615	COG0205	6-phosphofructokinase activity
EXW38_RS22630	COG1725	Transcriptional regulator
EXW38_RS22635	COG0281	malic enzyme
EXW38_RS22640	COG0587	DNA-directed DNA polymerase activity
EXW38_RS22655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW38_RS22670	COG4109	DRTGG domain
EXW38_RS22680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW38_RS22685	COG0006	proline dipeptidase activity
EXW38_RS22725	COG1476	TRANSCRIPTIONal
EXW38_RS22740	COG1028	Short-chain dehydrogenase reductase Sdr
EXW38_RS22745	COG0589	response to stress
EXW38_RS22765	COG0165	Argininosuccinate lyase
EXW38_RS22770	COG0137	argininosuccinate synthase activity
EXW38_RS22785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS22800	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW38_RS22805	COG0827	DNA restriction-modification system
EXW38_RS22810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW38_RS22815	COG3874	Sporulation protein YtfJ
EXW38_RS22830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW38_RS22840	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_RS22855	COG1104	cysteine desulfurase activity
EXW38_RS22860	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW38_RS22875	COG1309	transcriptional regulator
EXW38_RS22880	COG1956	GAF domain-containing protein
EXW38_RS22885	COG0626	cystathionine gamma-synthase activity
EXW38_RS22890	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW38_RS22915	COG1595	DNA-templated transcription, initiation
EXW38_RS22925	COG0110	maltose O-acetyltransferase activity
EXW38_RS22930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW38_RS22935	COG0454	-acetyltransferase
EXW38_RS22940	COG0517	IMP dehydrogenase activity
EXW38_RS22945	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW38_RS22960	COG0745	RESPONSE REGULATOR receiver
EXW38_RS22965	COG5002	protein histidine kinase activity
EXW38_RS22970	COG0666	response to abiotic stimulus
EXW38_RS22980	COG1970	mechanosensitive ion channel activity
EXW38_RS23000	COG1609	Transcriptional regulator
EXW38_RS23005	COG4851	CamS sex pheromone cAM373 precursor
EXW38_RS23010	COG3118	belongs to the thioredoxin family
EXW38_RS23020	COG2309	aminopeptidase activity
EXW38_RS23040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS23045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW38_RS23055	COG1674	ftsk spoiiie
EXW38_RS23070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_RS23075	COG4848	Belongs to the UPF0354 family
EXW38_RS23080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_RS23085	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW38_RS23090	COG1363	Peptidase, m42
EXW38_RS23100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS23105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW38_RS23115	COG0510	thiamine kinase activity
EXW38_RS23120	COG1523	belongs to the glycosyl hydrolase 13 family
EXW38_RS23130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW38_RS23135	COG1349	DNA-binding transcription factor activity
EXW38_RS23140	COG1187	pseudouridine synthase activity
EXW38_RS23145	COG2244	polysaccharide biosynthetic process
EXW38_RS23150	COG2081	HI0933 family
EXW38_RS23155	COG2814	Major facilitator Superfamily
EXW38_RS23165	COG3832	glyoxalase III activity
EXW38_RS23185	COG1329	Transcriptional regulator
EXW38_RS23200	COG0314	molybdopterin synthase activity
EXW38_RS23205	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW38_RS23210	COG0303	'Molybdopterin
EXW38_RS23215	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW38_RS23220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_RS23225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW38_RS23245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW38_RS23255	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW38_RS23295	COG0495	leucyl-tRNA aminoacylation
EXW38_RS23300	COG2814	Major facilitator Superfamily
EXW38_RS23305	COG0475	glutathione-regulated potassium exporter activity
EXW38_RS23310	COG0490	domain, Protein
EXW38_RS23315	COG0582	viral genome integration into host DNA
EXW38_RS23325	COG1136	(ABC) transporter
EXW38_RS23340	COG1242	4 iron, 4 sulfur cluster binding
EXW38_RS23345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW38_RS23350	COG1794	racemase activity, acting on amino acids and derivatives
EXW38_RS23370	COG2267	carboxylic ester hydrolase activity
EXW38_RS23375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW38_RS23380	COG0671	phosphoesterase, PA-phosphatase related
EXW38_RS23385	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS23395	COG1404	Belongs to the peptidase S8 family
EXW38_RS23400	COG2197	response regulator
EXW38_RS23405	COG4585	Histidine kinase
EXW38_RS23410	COG0746	molybdenum cofactor guanylyltransferase activity
EXW38_RS23430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW38_RS23435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW38_RS23470	COG5002	protein histidine kinase activity
EXW38_RS23475	COG3852	Histidine kinase
EXW38_RS23480	COG0753	catalase activity
EXW38_RS23485	COG2267	carboxylic ester hydrolase activity
EXW38_RS23490	COG1368	sulfuric ester hydrolase activity
EXW38_RS23495	COG4895	conserved protein (DUF2196)
EXW38_RS23510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW38_RS23515	COG1116	anion transmembrane transporter activity
EXW38_RS23520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW38_RS23540	COG0494	nUDIX hydrolase
EXW38_RS23575	COG2723	6-phospho-beta-galactosidase activity
EXW38_RS23580	COG2723	6-phospho-beta-galactosidase activity
EXW38_RS23585	COG1263	PTS System
EXW38_RS23585	COG2190	(PTS) system
EXW38_RS23585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS23590	COG3711	transcriptional antiterminator
EXW38_RS23595	COG1854	S-ribosylhomocysteine lyase activity
EXW38_RS23605	COG0288	reversible hydration of carbon dioxide
EXW38_RS23610	COG1271	oxidase subunit
EXW38_RS23615	COG1294	oxidase, subunit
EXW38_RS23630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS23655	COG1842	Phage shock protein A
EXW38_RS23680	COG3859	Proton-coupled thiamine transporter YuaJ
EXW38_RS23685	COG5002	protein histidine kinase activity
EXW38_RS23690	COG0745	RESPONSE REGULATOR receiver
EXW38_RS23715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW38_RS23720	COG1597	lipid kinase activity
EXW38_RS23750	COG1136	(ABC) transporter
EXW38_RS23765	COG5002	protein histidine kinase activity
EXW38_RS23775	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS23785	COG0577	efflux transmembrane transporter activity
EXW38_RS23790	COG1136	(ABC) transporter
EXW38_RS23795	COG2207	Transcriptional regulator
EXW38_RS23795	COG3708	Transcriptional regulator
EXW38_RS23805	COG1131	(ABC) transporter
EXW38_RS23810	COG5658	integral membrane protein
EXW38_RS23815	COG0640	Transcriptional regulator
EXW38_RS23820	COG0745	RESPONSE REGULATOR receiver
EXW38_RS23825	COG2205	protein histidine kinase activity
EXW38_RS23830	COG0577	efflux transmembrane transporter activity
EXW38_RS23835	COG0577	efflux transmembrane transporter activity
EXW38_RS23840	COG1136	(ABC) transporter
EXW38_RS23845	COG0577	efflux transmembrane transporter activity
EXW38_RS23860	COG2188	Transcriptional regulator
EXW38_RS23880	COG3964	amidohydrolase
EXW38_RS23900	COG4948	Mandelate Racemase Muconate Lactonizing
EXW38_RS23905	COG0318	PFAM AMP-dependent synthetase and ligase
EXW38_RS23910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW38_RS23915	COG0596	Alpha beta hydrolase
EXW38_RS23920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW38_RS23925	COG1169	isochorismate synthase
EXW38_RS23930	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW38_RS23935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW38_RS23940	COG1278	Cold shock
EXW38_RS23950	COG1051	belongs to the nudix hydrolase family
EXW38_RS23960	COG0058	SHG alpha-glucan phosphorylase activity
EXW38_RS23970	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW38_RS23975	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW38_RS23980	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW38_RS24115	COG1285	pathogenesis
EXW38_RS24120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW38_RS24130	COG0166	Belongs to the GPI family
EXW38_RS24135	COG2155	Conserved Protein
EXW38_RS24140	COG1098	S1 RNA binding domain
EXW38_RS24145	COG0436	Aminotransferase
EXW38_RS24150	COG1522	sequence-specific DNA binding
EXW38_RS24155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW38_RS24160	COG2267	carboxylic ester hydrolase activity
EXW38_RS24170	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW38_RS24200	COG5018	Exonuclease
EXW38_RS24205	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_RS24225	COG2050	protein possibly involved in aromatic compounds catabolism
EXW38_RS24235	COG1268	BioY protein
EXW38_RS24240	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW38_RS24245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW38_RS24255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW38_RS24260	COG3584	3D domain protein
EXW38_RS24275	COG1252	NADH dehydrogenase
EXW38_RS24280	COG0492	ferredoxin-NADP+ reductase activity
EXW38_RS24285	COG3708	Transcriptional regulator
EXW38_RS24300	COG1683	Conserved Protein
EXW38_RS24310	COG0316	Belongs to the HesB IscA family
EXW38_RS24315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW38_RS24320	COG4844	belongs to the
EXW38_RS24325	COG1252	NADH dehydrogenase
EXW38_RS24330	COG2274	protein secretion by the type I secretion system
EXW38_RS24335	COG0390	transport system, permease component
EXW38_RS24340	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW38_RS24375	COG4837	Protein of unknown function (DUF1462)
EXW38_RS24380	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW38_RS24390	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_RS24395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW38_RS24410	COG1136	(ABC) transporter
EXW38_RS24410	COG0577	efflux transmembrane transporter activity
EXW38_RS24415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS24425	COG0647	UMP catabolic process
EXW38_RS24435	COG2445	Protein of unknown function DUF86
EXW38_RS24440	COG1494	fructose-1,6-bisphosphatase
EXW38_RS24460	COG4470	Protein conserved in bacteria
EXW38_RS24470	COG0789	Transcriptional regulator
EXW38_RS24475	COG4377	Putative membrane peptidase family (DUF2324)
EXW38_RS24500	COG0739	heme binding
EXW38_RS24510	COG3377	Domain of unknown function (DUF1805)
EXW38_RS24515	COG0737	Belongs to the 5'-nucleotidase family
EXW38_RS24520	COG0719	Fe-S assembly protein
EXW38_RS24525	COG0822	iron-sulfur transferase activity
EXW38_RS24530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW38_RS24535	COG0719	Fe-S assembly protein
EXW38_RS24540	COG0396	ATPase activity
EXW38_RS24545	COG1464	Belongs to the NlpA lipoprotein family
EXW38_RS24550	COG1464	Belongs to the NlpA lipoprotein family
EXW38_RS24555	COG2011	ABC-type metal ion transport system permease component
EXW38_RS24570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW38_RS24575	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW38_RS24580	COG0509	glycine decarboxylation via glycine cleavage system
EXW38_RS24585	COG1393	Belongs to the ArsC family
EXW38_RS24620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS24635	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS24640	COG0183	Belongs to the thiolase family
EXW38_RS24645	COG1024	Enoyl-CoA hydratase
EXW38_RS24645	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_RS24655	COG1686	Belongs to the peptidase S11 family
EXW38_RS24660	COG0506	proline dehydrogenase activity
EXW38_RS24670	COG0011	TIGRFAM Protein of
EXW38_RS24675	COG0840	transmembrane signaling receptor activity
EXW38_RS24690	COG2814	Major facilitator Superfamily
EXW38_RS24695	COG0531	amino acid
EXW38_RS24715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW38_RS24745	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS24755	COG1376	ErfK ybiS ycfS ynhG family protein
EXW38_RS24760	COG0745	RESPONSE REGULATOR receiver
EXW38_RS24765	COG5002	protein histidine kinase activity
EXW38_RS24775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW38_RS24785	COG0840	transmembrane signaling receptor activity
EXW38_RS24790	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW38_RS24795	COG3227	Zinc metalloprotease (Elastase)
EXW38_RS24800	COG1741	Belongs to the pirin family
EXW38_RS24815	COG0586	Pfam SNARE associated Golgi protein
EXW38_RS24820	COG0475	glutathione-regulated potassium exporter activity
EXW38_RS24825	COG0490	domain, Protein
EXW38_RS24830	COG1115	amino acid carrier protein
EXW38_RS24835	COG0783	Belongs to the Dps family
EXW38_RS24845	COG2318	DinB family
EXW38_RS24850	COG1611	Belongs to the LOG family
EXW38_RS24860	COG1528	Iron-storage protein
EXW38_RS24865	COG2311	Membrane
EXW38_RS24870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS24875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS24880	COG1115	amino acid carrier protein
EXW38_RS24885	COG2910	NAD(P)H-binding
EXW38_RS24895	COG0656	L-ascorbic acid biosynthetic process
EXW38_RS24900	COG2814	Major facilitator Superfamily
EXW38_RS24905	COG1733	regulation of RNA biosynthetic process
EXW38_RS24915	COG1252	NADH dehydrogenase
EXW38_RS24975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS24985	COG1733	regulation of RNA biosynthetic process
EXW38_RS24990	COG1522	sequence-specific DNA binding
EXW38_RS24995	COG0288	reversible hydration of carbon dioxide
EXW38_RS25000	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW38_RS25005	COG2233	PERMEase
EXW38_RS25030	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS25050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW38_RS25055	COG0557	exoribonuclease II activity
EXW38_RS25060	COG1647	Serine aminopeptidase, S33
EXW38_RS25065	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW38_RS25070	COG1346	cytolysis
EXW38_RS25095	COG0149	triose-phosphate isomerase activity
EXW38_RS25100	COG0126	phosphoglycerate kinase activity
EXW38_RS25105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW38_RS25120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW38_RS25145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW38_RS25160	COG2323	membrane
EXW38_RS25170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW38_RS25175	COG1481	regulation of sporulation
EXW38_RS25180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW38_RS25185	COG1660	Displays ATPase and GTPase activities
EXW38_RS25190	COG1051	belongs to the nudix hydrolase family
EXW38_RS25200	COG0492	ferredoxin-NADP+ reductase activity
EXW38_RS25205	COG0457	Tetratricopeptide repeat
EXW38_RS25210	COG0110	maltose O-acetyltransferase activity
EXW38_RS25215	COG0546	phosphoglycolate phosphatase activity
EXW38_RS25220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW38_RS25225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW38_RS25230	COG1950	PFAM Membrane protein of
EXW38_RS25240	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW38_RS25255	COG0789	Transcriptional regulator
EXW38_RS25290	COG0583	DNA-binding transcription factor activity
EXW38_RS25295	COG0789	Transcriptional regulator
EXW38_RS25300	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS25305	COG0488	(ABC) transporter
EXW38_RS25315	COG1132	(ABC) transporter
EXW38_RS25320	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW38_RS25325	COG0583	DNA-binding transcription factor activity
EXW38_RS25330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_RS25335	COG3409	Peptidoglycan-binding domain 1 protein
EXW38_RS25335	COG0793	Belongs to the peptidase S41A family
EXW38_RS25340	COG2177	Part of the ABC transporter FtsEX involved in
EXW38_RS25345	COG2884	Cell division ATP-binding protein ftsE
EXW38_RS25380	COG1278	Cold shock
EXW38_RS25385	COG1040	competence protein
EXW38_RS25390	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW38_RS25395	COG0791	NLP P60 protein
EXW38_RS25395	COG1388	LysM domain
EXW38_RS25400	COG1733	regulation of RNA biosynthetic process
EXW38_RS25405	COG1307	EDD domain protein, DegV family
EXW38_RS25410	COG1739	Uncharacterized protein family UPF0029
EXW38_RS25415	COG1316	TRANSCRIPTIONal
EXW38_RS25420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW38_RS25425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW38_RS25430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW38_RS25440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW38_RS25440	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW38_RS25460	COG1486	melibiose metabolic process
EXW38_RS25465	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_RS25470	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS25480	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW38_RS25490	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW38_RS25500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW38_RS25505	COG1301	dicarboxylic acid transport
EXW38_RS25520	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW38_RS25530	COG1271	oxidase subunit
EXW38_RS25535	COG1294	oxidase, subunit
EXW38_RS25540	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW38_RS25545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW38_RS25550	COG1620	l-lactate permease
EXW38_RS25560	COG2389	metal-binding protein
EXW38_RS25570	COG1368	sulfuric ester hydrolase activity
EXW38_RS25580	COG1388	LysM domain
EXW38_RS25580	COG0791	NLP P60 protein
EXW38_RS25585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW38_RS25595	COG1215	transferase activity, transferring glycosyl groups
EXW38_RS25600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW38_RS25605	COG1388	LysM domain
EXW38_RS25605	COG3584	3D domain protein
EXW38_RS25615	COG4715	Zinc finger, swim domain protein
EXW38_RS25620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW38_RS25665	COG0577	efflux transmembrane transporter activity
EXW38_RS25670	COG1136	(ABC) transporter
EXW38_RS25700	COG0745	RESPONSE REGULATOR receiver
EXW38_RS25705	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_RS25720	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW38_RS25735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW38_RS25750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_RS25770	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW38_RS25780	COG1682	transport, permease protein
EXW38_RS25785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EXW38_RS25830	COG1609	Transcriptional regulator
EXW38_RS25845	COG0110	maltose O-acetyltransferase activity
EXW38_RS25870	COG0739	heme binding
EXW38_RS25885	COG4555	ABC transporter
EXW38_RS25890	COG2385	sporulation resulting in formation of a cellular spore
EXW38_RS25905	COG4836	Membrane
EXW38_RS25910	COG1007	ATP synthesis coupled electron transport
EXW38_RS25915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_RS25920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW38_RS25925	COG0713	ATP synthesis coupled electron transport
EXW38_RS25930	COG0839	Belongs to the complex I subunit 6 family
EXW38_RS25940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW38_RS25945	COG0649	NAD binding
EXW38_RS25950	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_RS25955	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_RS25960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW38_RS25965	COG3300	MHYT domain
EXW38_RS25965	COG5001	Diguanylate cyclase
EXW38_RS25980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW38_RS25985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW38_RS25990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW38_RS25995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW38_RS26005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW38_RS26015	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW38_RS26050	COG0698	ribose 5-phosphate isomerase
EXW38_RS26060	COG2190	(PTS) system
EXW38_RS26065	COG2259	Doxx family
EXW38_RS26070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW38_RS26080	COG1971	Probably functions as a manganese efflux pump
EXW38_RS26085	COG0009	L-threonylcarbamoyladenylate synthase
EXW38_RS26100	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW38_RS26105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW38_RS26110	COG1435	thymidine kinase activity
EXW38_RS26120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW38_RS26125	COG1494	fructose-1,6-bisphosphatase
EXW38_RS26145	COG4821	SIS domain
EXW38_RS26150	COG0504	CTP synthase activity
EXW38_RS26165	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS26170	COG1960	acyl-CoA dehydrogenase activity
EXW38_RS26175	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW38_RS26180	COG0183	Belongs to the thiolase family
EXW38_RS26185	COG0247	lactate metabolic process
EXW38_RS26185	COG2181	nitrate reductase activity
EXW38_RS26190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW38_RS26195	COG4294	response to UV
EXW38_RS26200	COG3300	MHYT domain
EXW38_RS26200	COG5001	Diguanylate cyclase
EXW38_RS26215	COG3227	Zinc metalloprotease (Elastase)
EXW38_RS26220	COG2197	response regulator
EXW38_RS26225	COG4585	Histidine kinase
EXW38_RS26230	COG0842	Transport permease protein
EXW38_RS26235	COG1131	(ABC) transporter
EXW38_RS26240	COG0024	Methionine aminopeptidase
EXW38_RS26245	COG2234	aminopeptidase activity
EXW38_RS26260	COG4506	Protein conserved in bacteria
EXW38_RS26265	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW38_RS26290	COG2814	Major facilitator Superfamily
EXW38_RS26295	COG0789	Transcriptional regulator
EXW38_RS26300	COG0584	glycerophosphoryl diester phosphodiesterase
EXW38_RS26305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW38_RS26315	COG1994	Peptidase M50
EXW38_RS26325	COG1078	dGTPase activity
EXW38_RS26330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW38_RS26335	COG1120	ATPase activity
EXW38_RS26340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS26345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW38_RS26350	COG4844	belongs to the
EXW38_RS26365	COG0280	phosphate acetyltransferase
EXW38_RS26370	COG3253	May function as heme-dependent peroxidase
EXW38_RS26380	COG3773	Cell wall hydrolase
EXW38_RS26390	COG2363	Small membrane protein
EXW38_RS26400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW38_RS26405	COG2233	PERMEase
EXW38_RS26410	COG0561	phosphatase activity
EXW38_RS26415	COG2814	Major facilitator Superfamily
EXW38_RS26420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW38_RS26425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_RS26430	COG1131	(ABC) transporter
EXW38_RS26435	COG2755	lipolytic protein G-D-S-L family
EXW38_RS26440	COG1609	Transcriptional regulator
EXW38_RS26450	COG0460	homoserine dehydrogenase
EXW38_RS26455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW38_RS26460	COG2873	o-acetylhomoserine
EXW38_RS26475	COG2197	response regulator
EXW38_RS26480	COG2203	Gaf domain
EXW38_RS26480	COG4585	Histidine kinase
EXW38_RS26485	COG0351	phosphomethylpyrimidine kinase
EXW38_RS26490	COG3706	GGDEF domain
EXW38_RS26495	COG2879	small protein
EXW38_RS26500	COG1966	Carbon starvation protein
EXW38_RS26505	COG3279	Response regulator of the LytR AlgR family
EXW38_RS26510	COG0477	Major facilitator Superfamily
EXW38_RS26535	COG0840	transmembrane signaling receptor activity
EXW38_RS26545	COG1607	acyl-coa hydrolase
EXW38_RS26555	COG1216	Glycosyl transferase, family 2
EXW38_RS26560	COG0488	(ABC) transporter
EXW38_RS26575	COG0463	Glycosyl transferase, family 2
EXW38_RS26580	COG1309	transcriptional regulator
EXW38_RS26585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW38_RS26590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_RS26590	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW38_RS26595	COG0628	permease
EXW38_RS26605	COG1380	Effector of murein hydrolase LrgA
EXW38_RS26610	COG3279	Response regulator of the LytR AlgR family
EXW38_RS26615	COG3275	phosphorelay sensor kinase activity
EXW38_RS26620	COG2814	Major facilitator Superfamily
EXW38_RS26625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW38_RS26630	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW38_RS26675	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW38_RS26680	COG1272	protein, Hemolysin III
EXW38_RS26705	COG1164	Oligoendopeptidase f
EXW38_RS26720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW38_RS26730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW38_RS26735	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW38_RS26740	COG4853	Protein conserved in bacteria
EXW38_RS26750	COG5002	protein histidine kinase activity
EXW38_RS26755	COG0745	RESPONSE REGULATOR receiver
EXW38_RS26785	COG0305	Participates in initiation and elongation during chromosome replication
EXW38_RS26795	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW38_RS26800	COG4241	membrane
EXW38_RS26810	COG0629	single-stranded DNA binding
EXW38_RS26815	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW38_RS26820	COG0012	GTP binding
EXW38_RS26825	COG4481	Protein conserved in bacteria
EXW38_RS26830	COG0668	transmembrane transport
EXW38_RS26840	COG1475	DNA binding
EXW38_RS26845	COG1192	Involved in chromosome partitioning
EXW38_RS26850	COG1475	DNA binding
EXW38_RS26860	COG0445	tRNA wobble uridine modification
EXW38_RS26865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW38_RS26870	COG1847	R3H domain protein
EXW38_RS26875	COG0706	membrane insertase activity
EXW38_RS26880	COG0594	ribonuclease P activity
EXW38_RS26885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW38_RS26965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW38_RS26990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_RS27025	COG0561	phosphatase activity
EXW38_RS27035	COG1609	Transcriptional regulator
EXW38_RS27065	COG0494	nUDIX hydrolase
EXW38_RS27090	COG0739	heme binding
EXW38_RS27100	COG1595	DNA-templated transcription, initiation
EXW38_RS27195	COG0456	acetyltransferase
EXW38_RS27260	COG1278	Cold shock
EXW38_RS27280	COG0582	viral genome integration into host DNA
EXW38_RS27290	COG5566	PFAM Mor transcription activator
EXW38_RS27295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW38_RS27335	COG0531	amino acid
EXW38_RS27340	COG3338	carbonate dehydratase activity
EXW38_RS27350	COG5002	protein histidine kinase activity
EXW38_RS27380	COG5002	protein histidine kinase activity
EXW38_RS27390	COG0583	DNA-binding transcription factor activity
EXW38_RS27395	COG1741	Belongs to the pirin family
EXW38_RS27400	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW38_RS27405	COG3227	Zinc metalloprotease (Elastase)
EXW38_RS27445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW38_RS27455	COG2707	UPF0756 membrane protein
EXW38_RS27465	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW38_RS27470	COG4974	Belongs to the 'phage' integrase family
EXW38_RS27485	COG0583	DNA-binding transcription factor activity
EXW38_RS27490	COG4689	acetoacetate decarboxylase
EXW38_RS27515	COG0531	amino acid
EXW38_RS27525	COG2318	DinB family
EXW38_RS27530	COG2378	regulation of single-species biofilm formation
EXW38_RS27550	COG1309	transcriptional regulator
EXW38_RS27580	COG3739	integral membrane protein
EXW38_RS27585	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW38_RS27590	COG1131	(ABC) transporter
EXW38_RS27600	COG3655	Transcriptional regulator
EXW38_RS27635	COG1131	(ABC) transporter
EXW38_RS27655	COG0825	malonyl-CoA metabolic process
EXW38_RS27695	COG2814	Major facilitator Superfamily
EXW38_RS27700	COG0583	DNA-binding transcription factor activity
EXW38_RS27765	COG3493	citrate carrier protein
EXW38_RS27770	COG4565	transcriptional regulatory protein
EXW38_RS27775	COG3290	protein histidine kinase activity
EXW38_RS27785	COG0745	RESPONSE REGULATOR receiver
EXW38_RS27815	COG0753	catalase activity
EXW38_RS27970	COG1192	Involved in chromosome partitioning
EXW38_RS28110	COG3344	reverse transcriptase
EXW38_RS28115	COG0741	lytic transglycosylase activity
EXW38_RS28115	COG0791	NLP P60 protein
EXW38_RS28160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW38_RS28175	COG4152	abc transporter atp-binding protein
EXW38_RS28180	COG1668	transmembrane transport
EXW38_RS28235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW38_RS28285	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW38_RS28285	COG2755	lipolytic protein G-D-S-L family
EXW38_RS28325	COG0741	lytic transglycosylase activity
EXW38_RS28390	COG1136	(ABC) transporter
EXW38_RS28390	COG0577	efflux transmembrane transporter activity
EXW38_RS28465	COG0494	nUDIX hydrolase
EXW38_RS28555	COG1074	ATP-dependent DNA helicase activity
EXW38_RS28555	COG1074	ATP-dependent DNA helicase activity
EXW38_RS28565	COG0582	viral genome integration into host DNA
EXW38_RS28570	COG1401	restriction endodeoxyribonuclease activity
EXW38_RS28570	COG1401	restriction endodeoxyribonuclease activity
EXW38_RS28580	COG2003	Belongs to the UPF0758 family
EXW38_RS28595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW38_RS28605	COG3711	transcriptional antiterminator
EXW38_RS28610	COG2190	(PTS) system
EXW38_RS28610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW38_RS28610	COG1263	PTS System
EXW38_RS28615	COG2723	6-phospho-beta-galactosidase activity
EXW38_RS28650	COG3655	Transcriptional regulator
EXW38_RS28670	COG0662	Cupin 2, conserved barrel domain protein
EXW38_RS28745	COG5002	protein histidine kinase activity
EXW38_RS28825	COG1819	glycosyl
EXW38_RS28830	COG0156	8-amino-7-oxononanoate synthase activity
EXW38_RS28835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW38_RS28840	COG1136	(ABC) transporter
EXW38_RS28905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_RS28930	COG0577	efflux transmembrane transporter activity
EXW38_RS28935	COG1136	(ABC) transporter
EXW38_RS28950	COG1396	sequence-specific DNA binding
EXW38_RS28955	COG0006	proline dipeptidase activity
EXW38_RS28975	COG0582	viral genome integration into host DNA
EXW38_RS29005	COG2312	Erythromycin esterase
EXW38_RS29105	COG1073	alpha beta
EXW38_RS29125	COG1876	peptidase activity
EXW38_RS29155	COG4974	Belongs to the 'phage' integrase family
EXW38_RS29195	COG2814	Major facilitator Superfamily
EXW38_RS29200	COG1846	Transcriptional regulator
EXW38_RS29245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW38_RS29260	COG1923	regulation of RNA biosynthetic process
EXW38_RS29280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW38_RS29290	COG0814	amino acid
EXW38_RS29295	COG1760	l-serine dehydratase
EXW38_RS29300	COG1760	l-serine dehydratase
EXW38_RS29310	COG1136	(ABC) transporter
EXW38_RS29315	COG0500	methyltransferase
EXW38_RS29315	COG3615	Tellurite resistance protein tehB
EXW38_RS29360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW38_RS29380	COG2720	vancomycin resistance protein
EXW38_RS29400	COG1073	alpha beta
EXW38_RS29415	COG2318	DinB family
EXW38_RS29435	COG1309	transcriptional regulator
EXW38_RS29600	COG0686	Belongs to the AlaDH PNT family
EXW38_RS29605	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW38_RS29605	COG2508	Transcriptional regulator
EXW38_RS29615	COG2814	Major facilitator Superfamily
EXW38_RS29620	COG1309	transcriptional regulator
EXW38_RS29630	COG0582	viral genome integration into host DNA
EXW38_RS29660	COG0825	malonyl-CoA metabolic process
EXW38_RS29685	COG0662	Cupin 2, conserved barrel domain protein
EXW38_RS29720	COG1329	Transcriptional regulator
EXW38_RS29745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW38_RS29750	COG1011	Hydrolase
EXW38_RS29790	COG0789	Transcriptional regulator
EXW38_RS29810	COG0814	amino acid
EXW38_RS29815	COG0697	spore germination
EXW38_RS29960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW38_RS29990	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW38_RS30010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW38_RS30135	COG0463	Glycosyl transferase, family 2
EXW38_RS30160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW38_RS30165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW38_RS30170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW38_RS30175	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS30195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_RS30200	COG0438	transferase activity, transferring glycosyl groups
EXW38_RS30205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW38_RS30285	COG3773	Cell wall hydrolase
EXW38_RS30365	COG4166	transmembrane transport
EXW38_RS30395	COG1192	Involved in chromosome partitioning
EXW38_RS30420	COG1132	(ABC) transporter
EXW38_RS30430	COG0582	viral genome integration into host DNA
EXW38_RS30690	COG1671	Belongs to the UPF0178 family
EXW38_RS30720	COG2409	Drug exporters of the RND superfamily
EXW38_RS30725	COG2409	Drug exporters of the RND superfamily
EXW38_RS30780	COG1401	restriction endodeoxyribonuclease activity