locus-tag	class	description
EXW62_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW62_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW62_RS00015	COG2501	S4 domain
EXW62_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW62_RS00025	COG0187	DNA topoisomerase II activity
EXW62_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW62_RS00065	COG0516	GMP reductase activity
EXW62_RS00065	COG0517	IMP dehydrogenase activity
EXW62_RS00070	COG1686	Belongs to the peptidase S11 family
EXW62_RS00100	COG1428	Deoxynucleoside kinase
EXW62_RS00105	COG1428	Deoxynucleoside kinase
EXW62_RS00110	COG1335	isochorismatase
EXW62_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW62_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW62_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW62_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW62_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW62_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW62_RS00190	COG0470	DNA polymerase III
EXW62_RS00195	COG1774	PSP1 C-terminal conserved region
EXW62_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW62_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW62_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW62_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW62_RS00230	COG0084	hydrolase, TatD family'
EXW62_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW62_RS00250	COG4466	Protein conserved in bacteria
EXW62_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW62_RS00270	COG0251	oxidation-reduction process
EXW62_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW62_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW62_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW62_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW62_RS00310	COG2244	polysaccharide biosynthetic process
EXW62_RS00315	COG3956	TIGRFAM MazG family protein
EXW62_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW62_RS00340	COG1098	S1 RNA binding domain
EXW62_RS00355	COG2208	phosphoserine phosphatase activity
EXW62_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW62_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW62_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW62_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW62_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW62_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW62_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW62_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW62_RS00420	COG1396	sequence-specific DNA binding
EXW62_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW62_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW62_RS00515	COG3880	PFAM UvrB UvrC protein
EXW62_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW62_RS00525	COG0542	response to heat
EXW62_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW62_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW62_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW62_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW62_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW62_RS00560	COG1045	serine acetyltransferase
EXW62_RS00565	COG0215	cysteine-tRNA ligase activity
EXW62_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW62_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW62_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW62_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW62_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW62_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW62_RS00610	COG0081	regulation of translation
EXW62_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW62_RS00620	COG0222	ribosome binding
EXW62_RS00625	COG2813	Specifically methylates the guanine in position
EXW62_RS00630	COG0085	RNA polymerase activity
EXW62_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW62_RS00640	COG1358	cellular component organization or biogenesis
EXW62_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW62_RS00650	COG0049	tRNA binding
EXW62_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW62_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW62_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW62_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW62_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW62_RS00680	COG0089	rRNA binding
EXW62_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW62_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW62_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW62_RS00705	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EXW62_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW62_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW62_RS00720	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EXW62_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW62_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW62_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW62_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW62_RS00760	COG1841	ribosomal large subunit assembly
EXW62_RS00765	COG0200	Binds to the 23S rRNA
EXW62_RS00770	COG0201	protein transport
EXW62_RS00775	COG0563	adenylate kinase activity
EXW62_RS00780	COG0024	Methionine aminopeptidase
EXW62_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW62_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW62_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW62_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW62_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW62_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS00855	COG0489	protein tyrosine kinase activity
EXW62_RS00865	COG2194	sulfuric ester hydrolase activity
EXW62_RS00870	COG0726	polysaccharide deacetylase
EXW62_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW62_RS00955	COG4856	YbbR-like protein
EXW62_RS00970	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_RS00970	COG4946	Tricorn protease homolog
EXW62_RS00970	COG1506	peptidase
EXW62_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS00995	COG2011	ABC-type metal ion transport system permease component
EXW62_RS01005	COG1464	Belongs to the NlpA lipoprotein family
EXW62_RS01010	COG0604	alcohol dehydrogenase
EXW62_RS01020	COG0277	FAD linked oxidase domain protein
EXW62_RS01025	COG2271	Major facilitator Superfamily
EXW62_RS01035	COG2814	Major facilitator Superfamily
EXW62_RS01050	COG0601	transmembrane transport
EXW62_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_RS01060	COG0444	Belongs to the ABC transporter superfamily
EXW62_RS01065	COG4608	Belongs to the ABC transporter superfamily
EXW62_RS01070	COG4166	transmembrane transport
EXW62_RS01080	COG4166	transmembrane transport
EXW62_RS01085	COG4166	transmembrane transport
EXW62_RS01090	COG0656	L-ascorbic acid biosynthetic process
EXW62_RS01095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_RS01105	COG4149	molybdate abc transporter
EXW62_RS01110	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW62_RS01115	COG1910	domain protein
EXW62_RS01130	COG0697	spore germination
EXW62_RS01145	COG0204	Acyl-transferase
EXW62_RS01155	COG1609	Transcriptional regulator
EXW62_RS01165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS01180	COG5298	Protein conserved in bacteria
EXW62_RS01205	COG0488	(ABC) transporter
EXW62_RS01215	COG0747	negative chemotaxis
EXW62_RS01225	COG0601	transmembrane transport
EXW62_RS01230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_RS01235	COG0444	Belongs to the ABC transporter superfamily
EXW62_RS01240	COG4608	Belongs to the ABC transporter superfamily
EXW62_RS01245	COG0561	phosphatase activity
EXW62_RS01275	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW62_RS01280	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW62_RS01290	COG0531	amino acid
EXW62_RS01295	COG2814	Major facilitator Superfamily
EXW62_RS01305	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW62_RS01315	COG4294	response to UV
EXW62_RS01320	COG0705	Rhomboid family
EXW62_RS01325	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW62_RS01330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW62_RS01335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_RS01340	COG0864	Transcriptional regulator
EXW62_RS01345	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW62_RS01350	COG2183	response to ionizing radiation
EXW62_RS01455	COG0802	atpase or kinase
EXW62_RS01460	COG1214	PFAM Peptidase M22, glycoprotease
EXW62_RS01465	COG0456	acetyltransferase
EXW62_RS01475	COG0488	(ABC) transporter
EXW62_RS01480	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW62_RS01490	COG1266	CAAX protease self-immunity
EXW62_RS01495	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW62_RS01500	COG0459	protein refolding
EXW62_RS01505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW62_RS01505	COG0519	Catalyzes the synthesis of GMP from XMP
EXW62_RS01510	COG2252	PERMEase
EXW62_RS01520	COG5002	protein histidine kinase activity
EXW62_RS01540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW62_RS01600	COG2205	protein histidine kinase activity
EXW62_RS01605	COG0745	RESPONSE REGULATOR receiver
EXW62_RS01625	COG0697	spore germination
EXW62_RS01650	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW62_RS01655	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW62_RS01660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW62_RS01665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW62_RS01670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW62_RS01680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW62_RS01685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW62_RS01690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW62_RS01695	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW62_RS01700	COG0138	bifunctional purine biosynthesis protein purh
EXW62_RS01705	COG0151	Belongs to the GarS family
EXW62_RS01725	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW62_RS01730	COG0210	DNA helicase
EXW62_RS01735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW62_RS01740	COG4851	CamS sex pheromone cAM373 precursor
EXW62_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS01755	COG1335	isochorismatase
EXW62_RS01765	COG2011	ABC-type metal ion transport system permease component
EXW62_RS01770	COG1464	Belongs to the NlpA lipoprotein family
EXW62_RS01785	COG0003	Pfam Anion-transporting ATPase
EXW62_RS01790	COG1846	Transcriptional regulator
EXW62_RS01795	COG4682	membrane
EXW62_RS01805	COG0154	amidase activity
EXW62_RS01810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW62_RS01815	COG1597	lipid kinase activity
EXW62_RS01825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW62_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS01840	COG2076	Multidrug Resistance protein
EXW62_RS01850	COG2309	aminopeptidase activity
EXW62_RS01865	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS01875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW62_RS01880	COG5002	protein histidine kinase activity
EXW62_RS01885	COG4807	Protein conserved in bacteria
EXW62_RS01910	COG1757	Na H antiporter
EXW62_RS01915	COG1473	amidohydrolase
EXW62_RS01930	COG0450	alkyl hydroperoxide reductase
EXW62_RS01940	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW62_RS01950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS01955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS01960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS01965	COG0492	ferredoxin-NADP+ reductase activity
EXW62_RS01975	COG0166	Belongs to the GPI family
EXW62_RS02000	COG5002	protein histidine kinase activity
EXW62_RS02015	COG3541	Predicted nucleotidyltransferase
EXW62_RS02020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_RS02020	COG0723	plastoquinol--plastocyanin reductase activity
EXW62_RS02030	COG0765	amino acid transport
EXW62_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS02040	COG1126	abc transporter atp-binding protein
EXW62_RS02045	COG0840	transmembrane signaling receptor activity
EXW62_RS02050	COG0277	FAD linked oxidase domain protein
EXW62_RS02055	COG0366	Alpha amylase catalytic
EXW62_RS02060	COG1263	PTS System
EXW62_RS02060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_RS02060	COG2190	(PTS) system
EXW62_RS02080	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW62_RS02090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW62_RS02110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_RS02120	COG1116	anion transmembrane transporter activity
EXW62_RS02125	COG0488	(ABC) transporter
EXW62_RS02170	COG2270	Major facilitator Superfamily
EXW62_RS02205	COG2310	stress, protein
EXW62_RS02210	COG2310	stress, protein
EXW62_RS02215	COG2310	stress, protein
EXW62_RS02220	COG0861	Integral membrane protein TerC family
EXW62_RS02230	COG3853	Toxic anion resistance protein (TelA)
EXW62_RS02240	COG4840	Belongs to the UPF0435 family
EXW62_RS02245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW62_RS02255	COG1295	ribonuclease BN
EXW62_RS02260	COG2217	Heavy metal translocating P-type atpase
EXW62_RS02265	COG0697	spore germination
EXW62_RS02285	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS02300	COG3871	stress protein (general stress protein 26)
EXW62_RS02305	COG0387	Pfam Sodium calcium exchanger
EXW62_RS02315	COG0535	radical SAM domain protein
EXW62_RS02335	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW62_RS02355	COG3829	transcription factor binding
EXW62_RS02365	COG0833	amino acid
EXW62_RS02370	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_RS02390	COG2066	Belongs to the glutaminase family
EXW62_RS02395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_RS02395	COG1263	PTS System
EXW62_RS02400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_RS02420	COG1216	Glycosyl transferase, family 2
EXW62_RS02430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW62_RS02430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_RS02435	COG0463	Glycosyl transferase, family 2
EXW62_RS02450	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW62_RS02455	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW62_RS02470	COG1228	amidohydrolase
EXW62_RS02475	COG1090	epimerase
EXW62_RS02480	COG2137	regulation of response to DNA damage stimulus
EXW62_RS02505	COG1988	membrane-bound metal-dependent
EXW62_RS02510	COG1194	a g-specific adenine glycosylase
EXW62_RS02530	COG3557	Belongs to the UPF0374 family
EXW62_RS02535	COG1132	(ABC) transporter
EXW62_RS02540	COG4129	membrane
EXW62_RS02545	COG0070	glutamate synthase
EXW62_RS02545	COG0069	glutamate synthase activity
EXW62_RS02545	COG0067	glutamate synthase
EXW62_RS02550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW62_RS02555	COG4555	ABC transporter
EXW62_RS02575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW62_RS02580	COG0735	belongs to the Fur family
EXW62_RS02695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW62_RS02700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW62_RS02720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW62_RS02730	COG2766	serine protein kinase
EXW62_RS02735	COG2718	Belongs to the UPF0229 family
EXW62_RS02750	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW62_RS02755	COG2268	Band 7 protein
EXW62_RS02765	COG3290	protein histidine kinase activity
EXW62_RS02770	COG4565	transcriptional regulatory protein
EXW62_RS02775	COG2851	Citrate transporter
EXW62_RS02800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW62_RS02805	COG0745	RESPONSE REGULATOR receiver
EXW62_RS02810	COG5002	protein histidine kinase activity
EXW62_RS02820	COG4990	cell redox homeostasis
EXW62_RS02830	COG3290	protein histidine kinase activity
EXW62_RS02835	COG4565	transcriptional regulatory protein
EXW62_RS02840	COG3493	citrate carrier protein
EXW62_RS02845	COG0281	malic enzyme
EXW62_RS02855	COG0697	spore germination
EXW62_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS02870	COG5002	protein histidine kinase activity
EXW62_RS02875	COG0745	RESPONSE REGULATOR receiver
EXW62_RS02880	COG0456	acetyltransferase
EXW62_RS02885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW62_RS02890	COG3383	formate dehydrogenase (NAD+) activity
EXW62_RS02895	COG2427	Protein of unknown function (DUF1641)
EXW62_RS02910	COG0531	amino acid
EXW62_RS02920	COG0640	Transcriptional regulator
EXW62_RS02925	COG2217	Heavy metal translocating P-type atpase
EXW62_RS02930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW62_RS02945	COG3227	Zinc metalloprotease (Elastase)
EXW62_RS02965	COG2720	vancomycin resistance protein
EXW62_RS02970	COG1316	TRANSCRIPTIONal
EXW62_RS02975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS02980	COG0346	lactoylglutathione lyase activity
EXW62_RS02985	COG1253	flavin adenine dinucleotide binding
EXW62_RS02990	COG1027	Aspartate ammonia-lyase
EXW62_RS02995	COG1620	l-lactate permease
EXW62_RS03010	COG3104	oligopeptide transport
EXW62_RS03015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS03020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS03025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS03035	COG0500	methyltransferase
EXW62_RS03040	COG0156	8-amino-7-oxononanoate synthase activity
EXW62_RS03045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_RS03055	COG4548	von Willebrand factor, type A
EXW62_RS03060	COG0714	Associated with various cellular activities
EXW62_RS03090	COG0531	amino acid
EXW62_RS03095	COG2188	Transcriptional regulator
EXW62_RS03100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_RS03100	COG1263	PTS System
EXW62_RS03105	COG0366	Alpha amylase catalytic
EXW62_RS03120	COG0697	spore germination
EXW62_RS03130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_RS03135	COG1115	amino acid carrier protein
EXW62_RS03140	COG1126	abc transporter atp-binding protein
EXW62_RS03145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS03150	COG0765	amino acid transport
EXW62_RS03155	COG0765	amino acid transport
EXW62_RS03160	COG0833	amino acid
EXW62_RS03185	COG2378	regulation of single-species biofilm formation
EXW62_RS03190	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW62_RS03195	COG5002	protein histidine kinase activity
EXW62_RS03215	COG0659	secondary active sulfate transmembrane transporter activity
EXW62_RS03230	COG1846	Transcriptional regulator
EXW62_RS03235	COG0477	Major facilitator Superfamily
EXW62_RS03240	COG1609	Transcriptional regulator
EXW62_RS03245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW62_RS03250	COG1869	D-ribose catabolic process
EXW62_RS03260	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW62_RS03265	COG1879	ABC-type sugar transport system periplasmic component
EXW62_RS03285	COG1063	alcohol dehydrogenase
EXW62_RS03330	COG0840	transmembrane signaling receptor activity
EXW62_RS03335	COG3583	domain protein
EXW62_RS03335	COG3584	3D domain protein
EXW62_RS03340	COG1476	TRANSCRIPTIONal
EXW62_RS03360	COG3104	oligopeptide transport
EXW62_RS03365	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS03380	COG1113	amino acid transport
EXW62_RS03385	COG2252	PERMEase
EXW62_RS03400	COG2153	protein acetylation
EXW62_RS03410	COG0569	domain protein
EXW62_RS03410	COG0475	glutathione-regulated potassium exporter activity
EXW62_RS03420	COG1845	cytochrome c oxidase, subunit III
EXW62_RS03425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW62_RS03430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EXW62_RS03435	COG0833	amino acid
EXW62_RS03440	COG4990	cell redox homeostasis
EXW62_RS03455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_RS03460	COG0697	spore germination
EXW62_RS03465	COG0531	amino acid
EXW62_RS03475	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW62_RS03480	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW62_RS03490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW62_RS03495	COG0573	inorganic phosphate transmembrane transporter activity
EXW62_RS03500	COG0581	inorganic phosphate transmembrane transporter activity
EXW62_RS03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW62_RS03555	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW62_RS03635	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW62_RS03650	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS03650	COG3103	Sh3 type 3 domain protein
EXW62_RS03650	COG4991	sh3 domain protein
EXW62_RS03655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW62_RS03660	COG1116	anion transmembrane transporter activity
EXW62_RS03665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_RS03670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW62_RS03675	COG0352	thiamine-phosphate diphosphorylase activity
EXW62_RS03680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_RS03685	COG2104	thiamine diphosphate biosynthetic process
EXW62_RS03690	COG2022	thiamine diphosphate biosynthetic process
EXW62_RS03695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_RS03700	COG0351	phosphomethylpyrimidine kinase
EXW62_RS03720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW62_RS03725	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW62_RS03730	COG2205	protein histidine kinase activity
EXW62_RS03745	COG2252	PERMEase
EXW62_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS03810	COG0778	Nitroreductase
EXW62_RS03815	COG2719	SpoVR family
EXW62_RS03845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW62_RS03855	COG1937	Protein conserved in bacteria
EXW62_RS03860	COG0425	Belongs to the sulfur carrier protein TusA family
EXW62_RS03860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS03865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS03865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS03870	COG0425	Belongs to the sulfur carrier protein TusA family
EXW62_RS03875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS03880	COG2210	Belongs to the sulfur carrier protein TusA family
EXW62_RS03885	COG0730	response to heat
EXW62_RS03895	COG1316	TRANSCRIPTIONal
EXW62_RS03900	COG0604	alcohol dehydrogenase
EXW62_RS03905	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW62_RS03915	COG2814	Major facilitator Superfamily
EXW62_RS03925	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS03925	COG3711	transcriptional antiterminator
EXW62_RS03930	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_RS03935	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_RS03955	COG1388	LysM domain
EXW62_RS03955	COG3584	3D domain protein
EXW62_RS03960	COG0577	efflux transmembrane transporter activity
EXW62_RS03965	COG1136	(ABC) transporter
EXW62_RS03975	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW62_RS03990	COG0577	efflux transmembrane transporter activity
EXW62_RS03995	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS04000	COG3546	catalase activity
EXW62_RS04025	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS04055	COG0475	glutathione-regulated potassium exporter activity
EXW62_RS04065	COG1737	Transcriptional regulator
EXW62_RS04075	COG1263	PTS System
EXW62_RS04075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_RS04085	COG2259	Doxx family
EXW62_RS04105	COG0697	spore germination
EXW62_RS04110	COG1522	sequence-specific DNA binding
EXW62_RS04135	COG2076	Multidrug Resistance protein
EXW62_RS04140	COG1309	transcriptional regulator
EXW62_RS04145	COG2814	Major facilitator Superfamily
EXW62_RS04150	COG1733	regulation of RNA biosynthetic process
EXW62_RS04160	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_RS04190	COG4473	ABC transporter
EXW62_RS04195	COG0531	amino acid
EXW62_RS04200	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS04205	COG1132	(ABC) transporter
EXW62_RS04210	COG1132	(ABC) transporter
EXW62_RS04215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS04220	COG0765	amino acid transport
EXW62_RS04225	COG1126	abc transporter atp-binding protein
EXW62_RS04240	COG0189	ligase activity
EXW62_RS04255	COG3679	Belongs to the UPF0342 family
EXW62_RS04260	COG0028	Belongs to the TPP enzyme family
EXW62_RS04265	COG3527	Alpha-acetolactate decarboxylase
EXW62_RS04270	COG0463	Glycosyl transferase, family 2
EXW62_RS04275	COG1216	Glycosyl transferase, family 2
EXW62_RS04280	COG2094	Belongs to the DNA glycosylase MPG family
EXW62_RS04285	COG0561	phosphatase activity
EXW62_RS04295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW62_RS04300	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS04310	COG0659	secondary active sulfate transmembrane transporter activity
EXW62_RS04315	COG2244	polysaccharide biosynthetic process
EXW62_RS04335	COG1696	Membrane protein involved in D-alanine export
EXW62_RS04355	COG1024	Enoyl-CoA hydratase
EXW62_RS04370	COG1363	Peptidase, m42
EXW62_RS04385	COG2318	DinB family
EXW62_RS04405	COG0579	oxidoreductase
EXW62_RS04435	COG0601	transmembrane transport
EXW62_RS04440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_RS04445	COG0444	Belongs to the ABC transporter superfamily
EXW62_RS04450	COG4608	Belongs to the ABC transporter superfamily
EXW62_RS04560	COG0582	viral genome integration into host DNA
EXW62_RS04645	COG0305	Participates in initiation and elongation during chromosome replication
EXW62_RS04720	COG2814	Major facilitator Superfamily
EXW62_RS04725	COG0640	Transcriptional regulator
EXW62_RS04745	COG2376	Dihydroxyacetone kinase
EXW62_RS04755	COG2376	Dihydroxyacetone kinase
EXW62_RS04775	COG2720	vancomycin resistance protein
EXW62_RS04780	COG1335	isochorismatase
EXW62_RS04815	COG0076	glutamate decarboxylase activity
EXW62_RS04855	COG2807	transmembrane transport
EXW62_RS04860	COG2186	Transcriptional regulator
EXW62_RS04875	COG4585	Histidine kinase
EXW62_RS04880	COG2197	response regulator
EXW62_RS04910	COG0420	3'-5' exonuclease activity
EXW62_RS04915	COG4717	serine-type aminopeptidase activity
EXW62_RS04920	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW62_RS04925	COG0346	lactoylglutathione lyase activity
EXW62_RS04940	COG2267	carboxylic ester hydrolase activity
EXW62_RS04950	COG3620	sequence-specific DNA binding
EXW62_RS04955	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW62_RS04960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW62_RS04965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW62_RS04970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW62_RS04975	COG1595	DNA-templated transcription, initiation
EXW62_RS04995	COG3973	AAA domain
EXW62_RS05025	COG0537	adenosine 5'-monophosphoramidase activity
EXW62_RS05030	COG1131	(ABC) transporter
EXW62_RS05035	COG4473	ABC transporter
EXW62_RS05050	COG0247	lactate metabolic process
EXW62_RS05055	COG1139	Iron-sulfur cluster binding protein
EXW62_RS05060	COG1556	Lactate utilization protein
EXW62_RS05075	COG3402	PFAM membrane-flanked domain
EXW62_RS05080	COG3428	Bacterial PH domain
EXW62_RS05110	COG3402	PFAM membrane-flanked domain
EXW62_RS05115	COG3428	Bacterial PH domain
EXW62_RS05120	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_RS05125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_RS05130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW62_RS05135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW62_RS05140	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW62_RS05160	COG1309	transcriptional regulator
EXW62_RS05165	COG1511	domain protein
EXW62_RS05210	COG1609	Transcriptional regulator
EXW62_RS05220	COG1234	tRNA 3'-trailer cleavage
EXW62_RS05225	COG0095	Lipoate-protein ligase
EXW62_RS05235	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS05250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW62_RS05255	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW62_RS05260	COG4208	sulfate ABC transporter
EXW62_RS05295	COG1408	metallophosphoesterase
EXW62_RS05300	COG1078	dGTPase activity
EXW62_RS05310	COG1595	DNA-templated transcription, initiation
EXW62_RS05315	COG3708	Transcriptional regulator
EXW62_RS05315	COG2207	Transcriptional regulator
EXW62_RS05320	COG2205	protein histidine kinase activity
EXW62_RS05325	COG0745	RESPONSE REGULATOR receiver
EXW62_RS05345	COG0501	Belongs to the peptidase M48B family
EXW62_RS05350	COG0840	transmembrane signaling receptor activity
EXW62_RS05355	COG0697	spore germination
EXW62_RS05380	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW62_RS05385	COG2224	Isocitrate lyase
EXW62_RS05395	COG1278	Cold shock
EXW62_RS05405	COG4903	ComK protein
EXW62_RS05410	COG0398	Pfam SNARE associated Golgi protein
EXW62_RS05420	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW62_RS05425	COG1074	ATP-dependent DNA helicase activity
EXW62_RS05480	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW62_RS05505	COG0367	asparagine synthase
EXW62_RS05515	COG0753	catalase activity
EXW62_RS05525	COG0004	ammonium transporteR
EXW62_RS05535	COG1666	GTP binding
EXW62_RS05540	COG2996	Protein conserved in bacteria
EXW62_RS05555	COG1329	Transcriptional regulator
EXW62_RS05585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW62_RS05595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS05610	COG0561	phosphatase activity
EXW62_RS05630	COG2267	carboxylic ester hydrolase activity
EXW62_RS05645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_RS05650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW62_RS05655	COG5504	Zn-dependent protease
EXW62_RS05665	COG0180	Tryptophanyl-tRNA synthetase
EXW62_RS05675	COG4166	transmembrane transport
EXW62_RS05680	COG0601	transmembrane transport
EXW62_RS05685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW62_RS05690	COG0444	Belongs to the ABC transporter superfamily
EXW62_RS05695	COG4608	Belongs to the ABC transporter superfamily
EXW62_RS05700	COG0534	Mate efflux family protein
EXW62_RS05705	COG4166	transmembrane transport
EXW62_RS05720	COG0861	Integral membrane protein TerC family
EXW62_RS05725	COG4862	establishment of competence for transformation
EXW62_RS05730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_RS05740	COG1164	Oligoendopeptidase f
EXW62_RS05750	COG2346	COG2346, Truncated hemoglobins
EXW62_RS05755	COG4116	CYTH
EXW62_RS05765	COG2357	RelA SpoT domain protein
EXW62_RS05775	COG0564	pseudouridine synthase activity
EXW62_RS05785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW62_RS05790	COG0772	Belongs to the SEDS family
EXW62_RS05795	COG1216	Glycosyl transferase, family 2
EXW62_RS05815	COG0463	Glycosyl transferase, family 2
EXW62_RS05815	COG0457	Tetratricopeptide repeat
EXW62_RS05835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW62_RS05850	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW62_RS05895	COG2153	protein acetylation
EXW62_RS05905	COG2382	esterase
EXW62_RS05930	COG5492	domain, Protein
EXW62_RS05935	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_RS05945	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW62_RS05945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW62_RS05950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW62_RS05955	COG0134	indole-3-glycerol-phosphate synthase activity
EXW62_RS05960	COG0135	phosphoribosylanthranilate isomerase activity
EXW62_RS05965	COG0133	tryptophan synthase activity
EXW62_RS05970	COG0159	tryptophan synthase activity
EXW62_RS05980	COG1620	l-lactate permease
EXW62_RS05985	COG5634	Uncharacterized conserved protein (DUF2278)
EXW62_RS06045	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW62_RS06050	COG0567	Dehydrogenase, E1 component
EXW62_RS06055	COG1476	TRANSCRIPTIONal
EXW62_RS06100	COG1686	Belongs to the peptidase S11 family
EXW62_RS06105	COG0681	Belongs to the peptidase S26 family
EXW62_RS06140	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS06150	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW62_RS06155	COG1177	transmembrane transport
EXW62_RS06160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW62_RS06170	COG2409	Drug exporters of the RND superfamily
EXW62_RS06180	COG0564	pseudouridine synthase activity
EXW62_RS06190	COG2340	Cysteine-rich secretory protein family
EXW62_RS06195	COG0247	lactate metabolic process
EXW62_RS06200	COG0277	FAD linked oxidase domain protein
EXW62_RS06205	COG3835	regulator
EXW62_RS06215	COG0745	RESPONSE REGULATOR receiver
EXW62_RS06220	COG3850	Histidine kinase
EXW62_RS06220	COG5002	protein histidine kinase activity
EXW62_RS06225	COG2186	Transcriptional regulator
EXW62_RS06230	COG0247	lactate metabolic process
EXW62_RS06235	COG1139	Iron-sulfur cluster binding protein
EXW62_RS06240	COG1556	Lactate utilization protein
EXW62_RS06245	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW62_RS06250	COG2116	formate transmembrane transporter activity
EXW62_RS06255	COG0861	Integral membrane protein TerC family
EXW62_RS06260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_RS06270	COG2030	dehydratase
EXW62_RS06290	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS06295	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW62_RS06305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_RS06320	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW62_RS06325	COG3842	ATPase activity
EXW62_RS06335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW62_RS06340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW62_RS06350	COG1349	DNA-binding transcription factor activity
EXW62_RS06360	COG0235	Class ii aldolase
EXW62_RS06370	COG2861	carbohydrate metabolic process
EXW62_RS06380	COG3852	Histidine kinase
EXW62_RS06385	COG1846	Transcriptional regulator
EXW62_RS06395	COG2318	DinB family
EXW62_RS06400	COG5002	protein histidine kinase activity
EXW62_RS06410	COG0720	synthase
EXW62_RS06420	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW62_RS06425	COG4873	Protein conserved in bacteria
EXW62_RS06440	COG0456	acetyltransferase
EXW62_RS06455	COG1780	Probably involved in ribonucleotide reductase function
EXW62_RS06475	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW62_RS06480	COG0531	amino acid
EXW62_RS06490	COG2204	response regulator
EXW62_RS06495	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS06505	COG1725	Transcriptional regulator
EXW62_RS06510	COG1131	(ABC) transporter
EXW62_RS06520	COG1131	(ABC) transporter
EXW62_RS06525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_RS06540	COG1522	sequence-specific DNA binding
EXW62_RS06550	COG1335	isochorismatase
EXW62_RS06560	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_RS06565	COG2070	2-Nitropropane dioxygenase
EXW62_RS06570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW62_RS06575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_RS06580	COG1696	Membrane protein involved in D-alanine export
EXW62_RS06605	COG0716	FMN binding
EXW62_RS06620	COG3173	Aminoglycoside phosphotransferase
EXW62_RS06645	COG1968	undecaprenyl-diphosphatase activity
EXW62_RS06665	COG1846	Transcriptional regulator
EXW62_RS06680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW62_RS06690	COG3874	Sporulation protein YtfJ
EXW62_RS06715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_RS06720	COG0028	Belongs to the TPP enzyme family
EXW62_RS06725	COG0440	acetolactate synthase activity
EXW62_RS06735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_RS06755	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW62_RS06760	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW62_RS06770	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW62_RS06775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW62_RS06780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW62_RS06785	COG0107	imidazoleglycerol-phosphate synthase activity
EXW62_RS06795	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW62_RS06800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW62_RS06815	COG1183	phosphatidylcholine synthase activity
EXW62_RS06820	COG1368	sulfuric ester hydrolase activity
EXW62_RS06830	COG0019	diaminopimelate decarboxylase activity
EXW62_RS06850	COG0529	Catalyzes the synthesis of activated sulfate
EXW62_RS06855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW62_RS06875	COG1648	precorrin-2 dehydrogenase activity
EXW62_RS06880	COG0733	neurotransmitter:sodium symporter activity
EXW62_RS06910	COG1757	Na H antiporter
EXW62_RS06930	COG4758	membrane
EXW62_RS06935	COG4585	Histidine kinase
EXW62_RS06940	COG2197	response regulator
EXW62_RS06950	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS07000	COG0730	response to heat
EXW62_RS07005	COG0306	phosphate transporter
EXW62_RS07010	COG1392	Phosphate transport regulator
EXW62_RS07015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_RS07030	COG3852	Histidine kinase
EXW62_RS07035	COG1801	Protein of unknown function DUF72
EXW62_RS07045	COG0582	viral genome integration into host DNA
EXW62_RS07050	COG5002	protein histidine kinase activity
EXW62_RS07065	COG0392	lysyltransferase activity
EXW62_RS07065	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW62_RS07080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW62_RS07085	COG1686	Belongs to the peptidase S11 family
EXW62_RS07090	COG2715	membrane protein required for spore maturation
EXW62_RS07095	COG0700	Nucleoside recognition
EXW62_RS07100	COG1187	pseudouridine synthase activity
EXW62_RS07110	COG1333	cytochrome c biogenesis protein
EXW62_RS07115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW62_RS07120	COG0745	RESPONSE REGULATOR receiver
EXW62_RS07125	COG5002	protein histidine kinase activity
EXW62_RS07130	COG2096	Adenosyltransferase
EXW62_RS07145	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW62_RS07150	COG1141	Ferredoxin
EXW62_RS07155	COG4955	Helix-turn-helix domain
EXW62_RS07160	COG0514	ATP-dependent DNA helicase (RecQ)
EXW62_RS07165	COG1266	CAAX protease self-immunity
EXW62_RS07175	COG1408	metallophosphoesterase
EXW62_RS07190	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW62_RS07205	COG0492	ferredoxin-NADP+ reductase activity
EXW62_RS07210	COG0252	asparaginase activity
EXW62_RS07220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW62_RS07230	COG1304	FMN binding
EXW62_RS07260	COG1160	GTP binding
EXW62_RS07265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW62_RS07285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_RS07300	COG0142	geranyltranstransferase activity
EXW62_RS07305	COG2226	methyltransferase
EXW62_RS07310	COG0142	geranyltranstransferase activity
EXW62_RS07325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW62_RS07335	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW62_RS07340	COG0457	Tetratricopeptide repeat
EXW62_RS07345	COG5582	Belongs to the UPF0302 family
EXW62_RS07360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW62_RS07365	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW62_RS07365	COG2010	Cytochrome c
EXW62_RS07370	COG4347	Protein of unknown function (DUF1405)
EXW62_RS07385	COG2738	Putative neutral zinc metallopeptidase
EXW62_RS07395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS07400	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW62_RS07405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW62_RS07410	COG1803	Methylglyoxal synthase
EXW62_RS07415	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_RS07420	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS07425	COG0617	tRNA 3'-terminal CCA addition
EXW62_RS07435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW62_RS07440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW62_RS07450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW62_RS07450	COG1199	ATP-dependent helicase activity
EXW62_RS07470	COG3935	DnaD domain protein
EXW62_RS07475	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW62_RS07485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_RS07485	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_RS07490	COG3331	DNA recombination
EXW62_RS07525	COG4474	Belongs to the UPF0398 family
EXW62_RS07530	COG3599	regulation of cell shape
EXW62_RS07540	COG0116	Belongs to the methyltransferase superfamily
EXW62_RS07550	COG1199	ATP-dependent helicase activity
EXW62_RS07555	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW62_RS07560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS07565	COG0024	Methionine aminopeptidase
EXW62_RS07575	COG2233	PERMEase
EXW62_RS07585	COG2311	Membrane
EXW62_RS07590	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_RS07600	COG0456	acetyltransferase
EXW62_RS07650	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_RS07665	COG0454	-acetyltransferase
EXW62_RS07685	COG0328	RNA-DNA hybrid ribonuclease activity
EXW62_RS07730	COG3403	YqcI/YcgG family
EXW62_RS07735	COG1280	lysine exporter protein (LysE YggA)
EXW62_RS07750	COG3162	membrane
EXW62_RS07755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW62_RS07760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_RS07770	COG0475	glutathione-regulated potassium exporter activity
EXW62_RS07775	COG0789	Transcriptional regulator
EXW62_RS07775	COG4978	Transcriptional regulator
EXW62_RS07785	COG2323	membrane
EXW62_RS07790	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW62_RS07815	COG2814	Major facilitator Superfamily
EXW62_RS07835	COG1923	regulation of RNA biosynthetic process
EXW62_RS07845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW62_RS07850	COG1360	Flagellar Motor Protein
EXW62_RS07855	COG2201	protein-glutamate methylesterase activity
EXW62_RS07860	COG0643	Histidine kinase
EXW62_RS07860	COG2198	Histidine kinase
EXW62_RS07865	COG1776	CheC inhibitor of MCP methylation
EXW62_RS07865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_RS07880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW62_RS07900	COG1256	bacterial-type flagellum assembly
EXW62_RS07905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_RS07925	COG1815	bacterial-type flagellum-dependent cell motility
EXW62_RS07930	COG1558	bacterial-type flagellum-dependent cell motility
EXW62_RS07940	COG1766	The M ring may be actively involved in energy transduction
EXW62_RS07945	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_RS07955	COG1157	protein secretion by the type III secretion system
EXW62_RS07975	COG1749	Flagellar hook protein flgE
EXW62_RS07990	COG0835	chemotaxis
EXW62_RS07990	COG0784	Response regulator, receiver
EXW62_RS08010	COG0861	Integral membrane protein TerC family
EXW62_RS08020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_RS08025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW62_RS08030	COG0741	lytic transglycosylase activity
EXW62_RS08040	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_RS08045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW62_RS08045	COG1776	CheC inhibitor of MCP methylation
EXW62_RS08055	COG1338	Plays a role in the flagellum-specific transport system
EXW62_RS08060	COG1987	bacterial-type flagellum assembly
EXW62_RS08070	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW62_RS08075	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW62_RS08080	COG1419	protein localization to endoplasmic reticulum
EXW62_RS08085	COG4787	bacterial-type flagellum-dependent cell motility
EXW62_RS08115	COG0412	Dienelactone hydrolase
EXW62_RS08120	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_RS08145	COG2814	Major facilitator Superfamily
EXW62_RS08155	COG0583	DNA-binding transcription factor activity
EXW62_RS08160	COG3842	ATPase activity
EXW62_RS08200	COG1686	Belongs to the peptidase S11 family
EXW62_RS08235	COG0367	asparagine synthase
EXW62_RS08265	COG1802	Transcriptional regulator
EXW62_RS08270	COG0697	spore germination
EXW62_RS08280	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS08280	COG1216	Glycosyl transferase, family 2
EXW62_RS08285	COG1757	Na H antiporter
EXW62_RS08295	COG0277	FAD linked oxidase domain protein
EXW62_RS08315	COG0534	Mate efflux family protein
EXW62_RS08320	COG3340	Belongs to the peptidase S51 family
EXW62_RS08340	COG0785	Cytochrome C biogenesis protein
EXW62_RS08360	COG3048	D-serine ammonia-lyase activity
EXW62_RS08365	COG2733	membrane
EXW62_RS08400	COG1131	(ABC) transporter
EXW62_RS08420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_RS08425	COG0528	UMP kinase activity
EXW62_RS08435	COG1027	Aspartate ammonia-lyase
EXW62_RS08440	COG0281	malic enzyme
EXW62_RS08445	COG4191	Histidine kinase
EXW62_RS08450	COG0784	Response regulator, receiver
EXW62_RS08455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_RS08465	COG2502	aspartate--ammonia ligase
EXW62_RS08495	COG1051	belongs to the nudix hydrolase family
EXW62_RS08500	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS08510	COG2814	Major facilitator Superfamily
EXW62_RS08535	COG1695	Transcriptional regulator
EXW62_RS08545	COG0477	Major facilitator Superfamily
EXW62_RS08565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW62_RS08570	COG2223	nitrite transmembrane transporter activity
EXW62_RS08575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_RS08590	COG2244	polysaccharide biosynthetic process
EXW62_RS08595	COG0733	neurotransmitter:sodium symporter activity
EXW62_RS08605	COG5566	PFAM Mor transcription activator
EXW62_RS08610	COG2323	membrane
EXW62_RS08625	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_RS08635	COG0129	dihydroxy-acid dehydratase activity
EXW62_RS08640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW62_RS08665	COG2814	Major facilitator Superfamily
EXW62_RS08670	COG3384	dioxygenase
EXW62_RS08695	COG4166	transmembrane transport
EXW62_RS08700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS08720	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW62_RS08725	COG1054	Belongs to the UPF0176 family
EXW62_RS08735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW62_RS08740	COG0531	amino acid
EXW62_RS08765	COG2390	Transcriptional regulator
EXW62_RS08775	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW62_RS08780	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS08785	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW62_RS08800	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW62_RS08820	COG0583	DNA-binding transcription factor activity
EXW62_RS08840	COG0006	proline dipeptidase activity
EXW62_RS08845	COG2132	Multicopper oxidase
EXW62_RS08855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_RS08875	COG1309	transcriptional regulator
EXW62_RS08880	COG1131	(ABC) transporter
EXW62_RS08940	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS08950	COG2372	response to copper ion
EXW62_RS08950	COG1276	copper resistance
EXW62_RS08955	COG4549	nuclear export factor GLE1
EXW62_RS08965	COG0697	spore germination
EXW62_RS08970	COG0583	DNA-binding transcription factor activity
EXW62_RS08975	COG1959	2 iron, 2 sulfur cluster binding
EXW62_RS08980	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW62_RS08985	COG0778	Nitroreductase
EXW62_RS08995	COG0628	permease
EXW62_RS09010	COG1231	oxidoreductase activity
EXW62_RS09015	COG0523	cobalamin synthesis protein
EXW62_RS09025	COG0411	ABC transporter
EXW62_RS09055	COG1942	4-Oxalocrotonate Tautomerase
EXW62_RS09070	COG0346	lactoylglutathione lyase activity
EXW62_RS09080	COG1271	oxidase subunit
EXW62_RS09085	COG1294	oxidase, subunit
EXW62_RS09090	COG4988	ABC transporter
EXW62_RS09095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW62_RS09125	COG1686	Belongs to the peptidase S11 family
EXW62_RS09140	COG1388	LysM domain
EXW62_RS09140	COG0791	NLP P60 protein
EXW62_RS09150	COG1132	(ABC) transporter
EXW62_RS09155	COG0745	RESPONSE REGULATOR receiver
EXW62_RS09160	COG5002	protein histidine kinase activity
EXW62_RS09165	COG0300	oxidoreductase activity
EXW62_RS09170	COG4122	O-methyltransferase activity
EXW62_RS09200	COG0460	homoserine dehydrogenase
EXW62_RS09210	COG0083	homoserine kinase activity
EXW62_RS09225	COG1316	TRANSCRIPTIONal
EXW62_RS09235	COG0745	RESPONSE REGULATOR receiver
EXW62_RS09240	COG5002	protein histidine kinase activity
EXW62_RS09255	COG1285	pathogenesis
EXW62_RS09260	COG1247	-acetyltransferase
EXW62_RS09280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_RS09290	COG1082	Xylose isomerase domain protein TIM barrel
EXW62_RS09300	COG2814	Major facilitator Superfamily
EXW62_RS09305	COG1279	arginine transmembrane transporter activity
EXW62_RS09310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS09320	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW62_RS09350	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW62_RS09355	COG0577	efflux transmembrane transporter activity
EXW62_RS09360	COG2002	toxin-antitoxin pair type II binding
EXW62_RS09365	COG1404	Belongs to the peptidase S8 family
EXW62_RS09370	COG0640	Transcriptional regulator
EXW62_RS09375	COG0667	Aldo Keto reductase
EXW62_RS09400	COG0840	transmembrane signaling receptor activity
EXW62_RS09415	COG3949	Membrane
EXW62_RS09420	COG0783	Belongs to the Dps family
EXW62_RS09435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW62_RS09445	COG1231	oxidoreductase activity
EXW62_RS09450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS09455	COG4989	oxidoreductase activity
EXW62_RS09460	COG0523	cobalamin synthesis protein
EXW62_RS09475	COG0456	acetyltransferase
EXW62_RS09480	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW62_RS09490	COG0702	epimerase
EXW62_RS09500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW62_RS09510	COG4166	transmembrane transport
EXW62_RS09525	COG0406	alpha-ribazole phosphatase activity
EXW62_RS09535	COG5337	Spore coat protein CotH
EXW62_RS09540	COG1051	belongs to the nudix hydrolase family
EXW62_RS09545	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS09550	COG2244	polysaccharide biosynthetic process
EXW62_RS09560	COG0701	Predicted permease
EXW62_RS09565	COG3689	TIGRFAM TIGR03943 family protein
EXW62_RS09570	COG1607	acyl-coa hydrolase
EXW62_RS09580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_RS09595	COG0702	epimerase
EXW62_RS09600	COG2839	Protein conserved in bacteria
EXW62_RS09605	COG1253	flavin adenine dinucleotide binding
EXW62_RS09620	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS09625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_RS09640	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS09650	COG1876	peptidase activity
EXW62_RS09680	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS09690	COG0561	phosphatase activity
EXW62_RS09695	COG1846	Transcriptional regulator
EXW62_RS09700	COG2814	Major facilitator Superfamily
EXW62_RS09710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_RS09730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS09735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS09765	COG0456	acetyltransferase
EXW62_RS09800	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_RS09865	COG3874	Sporulation protein YtfJ
EXW62_RS09890	COG2226	methyltransferase
EXW62_RS09915	COG0346	lactoylglutathione lyase activity
EXW62_RS09930	COG1595	DNA-templated transcription, initiation
EXW62_RS09950	COG0426	domain, Protein
EXW62_RS09950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW62_RS09960	COG0386	Belongs to the glutathione peroxidase family
EXW62_RS09965	COG1305	Transglutaminase-like
EXW62_RS09970	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW62_RS09975	COG0714	Associated with various cellular activities
EXW62_RS09980	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW62_RS09985	COG1140	nitrate reductase beta subunit
EXW62_RS09990	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW62_RS09995	COG2181	nitrate reductase activity
EXW62_RS10000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW62_RS10005	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW62_RS10010	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_RS10020	COG0314	molybdopterin synthase activity
EXW62_RS10030	COG2223	nitrite transmembrane transporter activity
EXW62_RS10035	COG1648	precorrin-2 dehydrogenase activity
EXW62_RS10035	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW62_RS10045	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW62_RS10045	COG1587	Uroporphyrinogen-III synthase
EXW62_RS10050	COG2146	nitrite reductase [NAD(P)H] activity
EXW62_RS10055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW62_RS10060	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW62_RS10085	COG2359	stage V sporulation protein S
EXW62_RS10095	COG1418	mRNA catabolic process
EXW62_RS10100	COG0488	(ABC) transporter
EXW62_RS10135	COG1413	lyase activity
EXW62_RS10150	COG2136	Putative SAM-dependent methyltransferase
EXW62_RS10150	COG2521	methyltransferase
EXW62_RS10155	COG0018	arginyl-trna synthetase
EXW62_RS10195	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW62_RS10200	COG0017	Asparaginyl-tRNA synthetase
EXW62_RS10205	COG0733	neurotransmitter:sodium symporter activity
EXW62_RS10230	COG2610	gluconate transmembrane transporter activity
EXW62_RS10235	COG1454	alcohol dehydrogenase
EXW62_RS10245	COG0456	acetyltransferase
EXW62_RS10250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW62_RS10255	COG1131	(ABC) transporter
EXW62_RS10260	COG4473	ABC transporter
EXW62_RS10270	COG0546	phosphoglycolate phosphatase activity
EXW62_RS10310	COG0768	penicillin binding
EXW62_RS10325	COG1272	protein, Hemolysin III
EXW62_RS10330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW62_RS10335	COG0805	protein transport
EXW62_RS10345	COG1307	EDD domain protein, DegV family
EXW62_RS10350	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW62_RS10355	COG1999	signal sequence binding
EXW62_RS10360	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW62_RS10365	COG0367	asparagine synthase
EXW62_RS10380	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS10385	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS10390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW62_RS10410	COG1335	isochorismatase
EXW62_RS10415	COG1051	belongs to the nudix hydrolase family
EXW62_RS10420	COG0668	transmembrane transport
EXW62_RS10425	COG2203	Gaf domain
EXW62_RS10425	COG4585	Histidine kinase
EXW62_RS10430	COG2197	response regulator
EXW62_RS10435	COG1737	Transcriptional regulator
EXW62_RS10440	COG1064	alcohol dehydrogenase
EXW62_RS10455	COG1070	Carbohydrate kinase
EXW62_RS10465	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW62_RS10485	COG0517	IMP dehydrogenase activity
EXW62_RS10485	COG1125	glycine betaine transport
EXW62_RS10490	COG1174	glycine betaine transport
EXW62_RS10525	COG1253	flavin adenine dinucleotide binding
EXW62_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS10535	COG5506	Protein of unknown function (DUF1694)
EXW62_RS10550	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_RS10555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW62_RS10560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW62_RS10565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_RS10570	COG0456	acetyltransferase
EXW62_RS10575	COG3829	transcription factor binding
EXW62_RS10580	COG1509	lysine 2,3-aminomutase activity
EXW62_RS10590	COG4479	Belongs to the UPF0346 family
EXW62_RS10615	COG4991	sh3 domain protein
EXW62_RS10615	COG0515	serine threonine protein kinase
EXW62_RS10615	COG3064	Membrane
EXW62_RS10625	COG0671	phosphoesterase, PA-phosphatase related
EXW62_RS10630	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW62_RS10635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_RS10690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW62_RS10710	COG4221	oxidoreductase activity
EXW62_RS10730	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW62_RS10730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_RS10740	COG2814	Major facilitator Superfamily
EXW62_RS10745	COG0372	Belongs to the citrate synthase family
EXW62_RS10750	COG2079	MmgE PrpD family protein
EXW62_RS10755	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW62_RS10760	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS10765	COG2084	Dehydrogenase
EXW62_RS10770	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS10775	COG1280	lysine exporter protein (LysE YggA)
EXW62_RS10780	COG1024	Enoyl-CoA hydratase
EXW62_RS10795	COG0420	3'-5' exonuclease activity
EXW62_RS10800	COG0419	ATPase involved in DNA repair
EXW62_RS10810	COG3397	chitin binding
EXW62_RS10820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW62_RS10835	COG2223	nitrite transmembrane transporter activity
EXW62_RS10840	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS10845	COG1169	isochorismate synthase
EXW62_RS10850	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW62_RS10855	COG1535	isochorismatase
EXW62_RS10855	COG3433	isochorismatase activity
EXW62_RS10860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW62_RS10865	COG3251	PFAM MbtH domain protein
EXW62_RS10870	COG2814	Major facilitator Superfamily
EXW62_RS10885	COG0776	regulation of translation
EXW62_RS10895	COG1115	amino acid carrier protein
EXW62_RS10900	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_RS10910	COG1187	pseudouridine synthase activity
EXW62_RS10915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW62_RS10920	COG3655	Transcriptional regulator
EXW62_RS10930	COG1136	(ABC) transporter
EXW62_RS10940	COG0596	Alpha beta hydrolase
EXW62_RS10955	COG0028	Belongs to the TPP enzyme family
EXW62_RS10980	COG4974	Belongs to the 'phage' integrase family
EXW62_RS11000	COG1253	flavin adenine dinucleotide binding
EXW62_RS11030	COG2267	carboxylic ester hydrolase activity
EXW62_RS11040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS11075	COG1309	transcriptional regulator
EXW62_RS11085	COG0697	spore germination
EXW62_RS11090	COG0531	amino acid
EXW62_RS11105	COG1247	-acetyltransferase
EXW62_RS11140	COG0596	Alpha beta hydrolase
EXW62_RS11145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW62_RS11160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS11185	COG0561	phosphatase activity
EXW62_RS11195	COG0583	DNA-binding transcription factor activity
EXW62_RS11200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW62_RS11210	COG0583	DNA-binding transcription factor activity
EXW62_RS11215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW62_RS11220	COG2258	MOSC domain
EXW62_RS11235	COG1132	(ABC) transporter
EXW62_RS11240	COG1132	(ABC) transporter
EXW62_RS11245	COG0582	viral genome integration into host DNA
EXW62_RS11280	COG1396	sequence-specific DNA binding
EXW62_RS11310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW62_RS11320	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW62_RS11325	COG1595	DNA-templated transcription, initiation
EXW62_RS11350	COG1649	PFAM Uncharacterised BCR, COG1649
EXW62_RS11370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW62_RS11375	COG2971	BadF BadG BcrA BcrD
EXW62_RS11395	COG1846	Transcriptional regulator
EXW62_RS11430	COG0500	methyltransferase
EXW62_RS11430	COG3615	Tellurite resistance protein tehB
EXW62_RS11440	COG0693	protein deglycase activity
EXW62_RS11450	COG0588	phosphoglycerate mutase activity
EXW62_RS11470	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_RS11480	COG0110	maltose O-acetyltransferase activity
EXW62_RS11490	COG1136	(ABC) transporter
EXW62_RS11515	COG1686	Belongs to the peptidase S11 family
EXW62_RS11565	COG0768	penicillin binding
EXW62_RS11570	COG1595	DNA-templated transcription, initiation
EXW62_RS11580	COG0768	penicillin binding
EXW62_RS11585	COG0768	penicillin binding
EXW62_RS11620	COG1252	NADH dehydrogenase
EXW62_RS11625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS11625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS11640	COG0697	spore germination
EXW62_RS11675	COG3397	chitin binding
EXW62_RS11680	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_RS11690	COG1408	metallophosphoesterase
EXW62_RS11700	COG1131	(ABC) transporter
EXW62_RS11710	COG1309	transcriptional regulator
EXW62_RS11720	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS11725	COG0439	Biotin carboxylase
EXW62_RS11730	COG0511	ligase activity, forming carbon-carbon bonds
EXW62_RS11735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_RS11740	COG1024	Enoyl-CoA hydratase
EXW62_RS11745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW62_RS11750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_RS11770	COG3344	reverse transcriptase
EXW62_RS11815	COG1686	Belongs to the peptidase S11 family
EXW62_RS11840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_RS11865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW62_RS11895	COG1733	regulation of RNA biosynthetic process
EXW62_RS11915	COG1942	4-Oxalocrotonate Tautomerase
EXW62_RS11920	COG0583	DNA-binding transcription factor activity
EXW62_RS11930	COG1309	transcriptional regulator
EXW62_RS11960	COG0697	spore germination
EXW62_RS11965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS12000	COG2323	membrane
EXW62_RS12020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS12025	COG0697	spore germination
EXW62_RS12030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW62_RS12035	COG0201	protein transport
EXW62_RS12045	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS12050	COG3227	Zinc metalloprotease (Elastase)
EXW62_RS12055	COG1523	belongs to the glycosyl hydrolase 13 family
EXW62_RS12075	COG1073	alpha beta
EXW62_RS12085	COG0577	efflux transmembrane transporter activity
EXW62_RS12090	COG1136	(ABC) transporter
EXW62_RS12110	COG5002	protein histidine kinase activity
EXW62_RS12115	COG0745	RESPONSE REGULATOR receiver
EXW62_RS12120	COG1011	Hydrolase
EXW62_RS12140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_RS12145	COG1183	phosphatidylcholine synthase activity
EXW62_RS12155	COG1132	(ABC) transporter
EXW62_RS12165	COG3961	Belongs to the TPP enzyme family
EXW62_RS12185	COG0322	excinuclease ABC activity
EXW62_RS12210	COG2318	DinB family
EXW62_RS12225	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW62_RS12245	COG3878	Protein conserved in bacteria
EXW62_RS12285	COG0592	DNA-directed DNA polymerase activity
EXW62_RS12290	COG2816	NAD+ diphosphatase activity
EXW62_RS12300	COG2223	nitrite transmembrane transporter activity
EXW62_RS12310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_RS12350	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_RS12365	COG2814	Major facilitator Superfamily
EXW62_RS12375	COG1132	(ABC) transporter
EXW62_RS12375	COG2375	cellular response to nickel ion
EXW62_RS12380	COG1132	(ABC) transporter
EXW62_RS12415	COG0768	penicillin binding
EXW62_RS12420	COG0671	phosphoesterase, PA-phosphatase related
EXW62_RS12425	COG0604	alcohol dehydrogenase
EXW62_RS12430	COG5002	protein histidine kinase activity
EXW62_RS12435	COG0745	RESPONSE REGULATOR receiver
EXW62_RS12445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_RS12455	COG2205	protein histidine kinase activity
EXW62_RS12470	COG1122	ATPase activity
EXW62_RS12475	COG4720	Psort location CytoplasmicMembrane, score
EXW62_RS12480	COG1794	racemase activity, acting on amino acids and derivatives
EXW62_RS12490	COG1819	glycosyl
EXW62_RS12500	COG0768	penicillin binding
EXW62_RS12505	COG5002	protein histidine kinase activity
EXW62_RS12510	COG0561	phosphatase activity
EXW62_RS12545	COG2124	cytochrome p450
EXW62_RS12575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW62_RS12585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS12590	COG0460	homoserine dehydrogenase
EXW62_RS12610	COG0577	efflux transmembrane transporter activity
EXW62_RS12615	COG1136	(ABC) transporter
EXW62_RS12635	COG0488	(ABC) transporter
EXW62_RS12640	COG0667	Aldo Keto reductase
EXW62_RS12645	COG0583	DNA-binding transcription factor activity
EXW62_RS12650	COG2205	protein histidine kinase activity
EXW62_RS12655	COG0745	RESPONSE REGULATOR receiver
EXW62_RS12665	COG3773	Cell wall hydrolase
EXW62_RS12700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS12715	COG2959	enzyme of heme biosynthesis
EXW62_RS12735	COG3483	tryptophan 2,3-dioxygenase activity
EXW62_RS12745	COG3844	kynureninase activity
EXW62_RS12750	COG1309	transcriptional regulator
EXW62_RS12780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS12785	COG1349	DNA-binding transcription factor activity
EXW62_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS12825	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_RS12825	COG0456	acetyltransferase
EXW62_RS12860	COG4176	ABC-type proline glycine betaine transport system permease component
EXW62_RS12865	COG0517	IMP dehydrogenase activity
EXW62_RS12865	COG4175	Glycine betaine
EXW62_RS12890	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW62_RS12895	COG2153	protein acetylation
EXW62_RS12905	COG1819	glycosyl
EXW62_RS12920	COG2205	protein histidine kinase activity
EXW62_RS12925	COG2315	Protein conserved in bacteria
EXW62_RS12980	COG3973	AAA domain
EXW62_RS12995	COG0514	ATP-dependent DNA helicase (RecQ)
EXW62_RS13025	COG4637	Psort location Cytoplasmic, score
EXW62_RS13045	COG1227	inorganic diphosphatase activity
EXW62_RS13050	COG2318	DinB family
EXW62_RS13075	COG1162	GTPase activity
EXW62_RS13080	COG1115	amino acid carrier protein
EXW62_RS13085	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS13090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW62_RS13100	COG3938	Belongs to the proline racemase family
EXW62_RS13105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_RS13145	COG3214	Protein conserved in bacteria
EXW62_RS13150	COG2318	DinB family
EXW62_RS13160	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS13170	COG4166	transmembrane transport
EXW62_RS13180	COG4948	Mandelate Racemase Muconate Lactonizing
EXW62_RS13200	COG0667	Aldo Keto reductase
EXW62_RS13245	COG2936	dipeptidyl-peptidase activity
EXW62_RS13255	COG0745	RESPONSE REGULATOR receiver
EXW62_RS13275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_RS13305	COG1307	EDD domain protein, DegV family
EXW62_RS13330	COG1335	isochorismatase
EXW62_RS13345	COG2814	Major facilitator Superfamily
EXW62_RS13355	COG1664	Polymer-forming cytoskeletal
EXW62_RS13360	COG0789	Transcriptional regulator
EXW62_RS13365	COG4533	DNA binding
EXW62_RS13370	COG2814	Major facilitator Superfamily
EXW62_RS13370	COG0477	Major facilitator Superfamily
EXW62_RS13385	COG2261	transglycosylase associated protein
EXW62_RS13400	COG2226	methyltransferase
EXW62_RS13435	COG0436	Aminotransferase
EXW62_RS13440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW62_RS13465	COG1131	(ABC) transporter
EXW62_RS13510	COG0628	permease
EXW62_RS13535	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW62_RS13550	COG0697	spore germination
EXW62_RS13570	COG4912	Dna alkylation repair
EXW62_RS13600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS13610	COG2814	Major facilitator Superfamily
EXW62_RS13615	COG1368	sulfuric ester hydrolase activity
EXW62_RS13625	COG0488	(ABC) transporter
EXW62_RS13635	COG1309	transcriptional regulator
EXW62_RS13650	COG0287	Prephenate dehydrogenase
EXW62_RS13665	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW62_RS13665	COG1605	Chorismate mutase
EXW62_RS13700	COG3584	3D domain protein
EXW62_RS13700	COG1388	LysM domain
EXW62_RS13710	COG0346	lactoylglutathione lyase activity
EXW62_RS13720	COG0431	NADPH-dependent FMN reductase
EXW62_RS13730	COG1595	DNA-templated transcription, initiation
EXW62_RS13750	COG0579	oxidoreductase
EXW62_RS13760	COG2390	Transcriptional regulator
EXW62_RS13765	COG1070	Carbohydrate kinase
EXW62_RS13785	COG0346	lactoylglutathione lyase activity
EXW62_RS13790	COG2329	Antibiotic biosynthesis monooxygenase
EXW62_RS13810	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW62_RS13815	COG2207	Transcriptional regulator
EXW62_RS13830	COG2207	Transcriptional regulator
EXW62_RS13845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS13850	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW62_RS13855	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW62_RS13860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_RS13865	COG3239	Fatty acid desaturase
EXW62_RS13875	COG3842	ATPase activity
EXW62_RS13900	COG1175	transmembrane transport
EXW62_RS13905	COG1349	DNA-binding transcription factor activity
EXW62_RS13915	COG3655	Transcriptional regulator
EXW62_RS13930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS13935	COG0346	lactoylglutathione lyase activity
EXW62_RS13965	COG0714	Associated with various cellular activities
EXW62_RS13985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW62_RS13990	COG0753	catalase activity
EXW62_RS14005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW62_RS14030	COG0714	Associated with various cellular activities
EXW62_RS14040	COG0778	Nitroreductase
EXW62_RS14045	COG1846	Transcriptional regulator
EXW62_RS14075	COG2814	Major facilitator Superfamily
EXW62_RS14105	COG0456	acetyltransferase
EXW62_RS14120	COG0697	spore germination
EXW62_RS14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS14145	COG0814	amino acid
EXW62_RS14150	COG0697	spore germination
EXW62_RS14180	COG5002	protein histidine kinase activity
EXW62_RS14185	COG0642	Histidine kinase
EXW62_RS14190	COG0745	RESPONSE REGULATOR receiver
EXW62_RS14195	COG0596	Alpha beta hydrolase
EXW62_RS14205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_RS14205	COG0456	acetyltransferase
EXW62_RS14230	COG0730	response to heat
EXW62_RS14240	COG0833	amino acid
EXW62_RS14250	COG4335	DNA alkylation repair
EXW62_RS14275	COG0768	penicillin binding
EXW62_RS14285	COG3104	oligopeptide transport
EXW62_RS14290	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW62_RS14305	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW62_RS14310	COG1984	allophanate hydrolase subunit 2
EXW62_RS14315	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW62_RS14320	COG1414	Transcriptional regulator
EXW62_RS14340	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS14365	COG0640	Transcriptional regulator
EXW62_RS14385	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW62_RS14410	COG0574	Belongs to the PEP-utilizing enzyme family
EXW62_RS14410	COG3848	Pyruvate phosphate dikinase
EXW62_RS14425	COG0730	response to heat
EXW62_RS14465	COG3347	Dehydrogenase
EXW62_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS14475	COG1070	Carbohydrate kinase
EXW62_RS14480	COG0235	Class ii aldolase
EXW62_RS14490	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW62_RS14500	COG4154	Belongs to the RbsD FucU family
EXW62_RS14520	COG0798	PFAM Bile acid sodium symporter
EXW62_RS14525	COG0346	lactoylglutathione lyase activity
EXW62_RS14530	COG0640	Transcriptional regulator
EXW62_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS14540	COG1522	sequence-specific DNA binding
EXW62_RS14555	COG0346	lactoylglutathione lyase activity
EXW62_RS14595	COG0745	RESPONSE REGULATOR receiver
EXW62_RS14600	COG5002	protein histidine kinase activity
EXW62_RS14600	COG3850	Histidine kinase
EXW62_RS14630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW62_RS14635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW62_RS14645	COG2309	aminopeptidase activity
EXW62_RS14655	COG1690	Belongs to the RtcB family
EXW62_RS14675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW62_RS14690	COG1136	(ABC) transporter
EXW62_RS14695	COG0577	efflux transmembrane transporter activity
EXW62_RS14715	COG5002	protein histidine kinase activity
EXW62_RS14715	COG3850	Histidine kinase
EXW62_RS14730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS14735	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_RS14750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW62_RS14805	COG2814	Major facilitator Superfamily
EXW62_RS14860	COG2849	repeat protein
EXW62_RS14865	COG5444	nuclease activity
EXW62_RS14890	COG1876	peptidase activity
EXW62_RS14895	COG2843	Capsule synthesis protein
EXW62_RS14910	COG0477	Major facilitator Superfamily
EXW62_RS14925	COG1846	Transcriptional regulator
EXW62_RS14930	COG2814	Major facilitator Superfamily
EXW62_RS14990	COG4257	antibiotic catabolic process
EXW62_RS14995	COG4187	Peptidase family M20/M25/M40
EXW62_RS15000	COG1414	Transcriptional regulator
EXW62_RS15005	COG0833	amino acid
EXW62_RS15030	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_RS15080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW62_RS15085	COG2356	endonuclease I
EXW62_RS15090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_RS15095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW62_RS15115	COG1785	Belongs to the alkaline phosphatase family
EXW62_RS15120	COG0778	Nitroreductase
EXW62_RS15125	COG1733	regulation of RNA biosynthetic process
EXW62_RS15135	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS15145	COG1131	(ABC) transporter
EXW62_RS15170	COG1011	Hydrolase
EXW62_RS15175	COG2365	Tyrosine phosphatase family
EXW62_RS15205	COG0628	permease
EXW62_RS15210	COG2261	transglycosylase associated protein
EXW62_RS15225	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW62_RS15235	COG1253	flavin adenine dinucleotide binding
EXW62_RS15240	COG0789	Transcriptional regulator
EXW62_RS15250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW62_RS15275	COG0697	spore germination
EXW62_RS15280	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW62_RS15285	COG3813	Protein conserved in bacteria
EXW62_RS15290	COG4702	Belongs to the UPF0303 family
EXW62_RS15300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS15315	COG0494	nUDIX hydrolase
EXW62_RS15330	COG0384	phenazine biosynthesis protein PhzF
EXW62_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS15350	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS15355	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW62_RS15360	COG1733	regulation of RNA biosynthetic process
EXW62_RS15365	COG0577	efflux transmembrane transporter activity
EXW62_RS15370	COG1136	(ABC) transporter
EXW62_RS15380	COG0745	RESPONSE REGULATOR receiver
EXW62_RS15385	COG5002	protein histidine kinase activity
EXW62_RS15385	COG3850	Histidine kinase
EXW62_RS15400	COG1191	sigma factor activity
EXW62_RS15430	COG1876	peptidase activity
EXW62_RS15460	COG0741	lytic transglycosylase activity
EXW62_RS15515	COG0657	acetylesterase activity
EXW62_RS15525	COG2814	Major facilitator Superfamily
EXW62_RS15530	COG1309	transcriptional regulator
EXW62_RS15540	COG0384	phenazine biosynthesis protein PhzF
EXW62_RS15555	COG2224	Isocitrate lyase
EXW62_RS15585	COG0814	amino acid
EXW62_RS15610	COG1151	hydroxylamine reductase activity
EXW62_RS15685	COG1695	Transcriptional regulator
EXW62_RS15690	COG0604	alcohol dehydrogenase
EXW62_RS15695	COG1113	amino acid transport
EXW62_RS15735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS15770	COG0745	RESPONSE REGULATOR receiver
EXW62_RS15775	COG5002	protein histidine kinase activity
EXW62_RS15780	COG2814	Major facilitator Superfamily
EXW62_RS15790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_RS15795	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS15805	COG0534	Mate efflux family protein
EXW62_RS15810	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS15815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW62_RS15830	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_RS15835	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_RS15855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS15860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS15870	COG3739	integral membrane protein
EXW62_RS15890	COG0583	DNA-binding transcription factor activity
EXW62_RS15915	COG1193	negative regulation of DNA recombination
EXW62_RS15935	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW62_RS15940	COG1164	Oligoendopeptidase f
EXW62_RS15945	COG2957	Belongs to the agmatine deiminase family
EXW62_RS15965	COG3781	membrane
EXW62_RS15980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW62_RS16015	COG3973	AAA domain
EXW62_RS16025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW62_RS16030	COG0640	Transcriptional regulator
EXW62_RS16035	COG0604	alcohol dehydrogenase
EXW62_RS16040	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW62_RS16060	COG2808	Putative FMN-binding domain
EXW62_RS16070	COG0277	FAD linked oxidase domain protein
EXW62_RS16100	COG2514	catechol 2,3-dioxygenase activity
EXW62_RS16105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS16110	COG1126	abc transporter atp-binding protein
EXW62_RS16115	COG0765	amino acid transport
EXW62_RS16120	COG2720	vancomycin resistance protein
EXW62_RS16135	COG0110	maltose O-acetyltransferase activity
EXW62_RS16145	COG1278	Cold shock
EXW62_RS16155	COG0716	FMN binding
EXW62_RS16190	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS16200	COG0165	Argininosuccinate lyase
EXW62_RS16215	COG4145	pantothenate transmembrane transporter activity
EXW62_RS16225	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS16230	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS16240	COG1657	PFAM Prenyltransferase squalene oxidase
EXW62_RS16245	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW62_RS16250	COG2962	Rard protein
EXW62_RS16255	COG3326	Membrane
EXW62_RS16260	COG0531	amino acid
EXW62_RS16295	COG2226	methyltransferase
EXW62_RS16300	COG4166	transmembrane transport
EXW62_RS16305	COG4166	transmembrane transport
EXW62_RS16310	COG4166	transmembrane transport
EXW62_RS16320	COG1131	(ABC) transporter
EXW62_RS16330	COG0673	inositol 2-dehydrogenase activity
EXW62_RS16335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW62_RS16340	COG0187	DNA topoisomerase II activity
EXW62_RS16345	COG1832	CoA-binding protein
EXW62_RS16350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_RS16355	COG0745	RESPONSE REGULATOR receiver
EXW62_RS16365	COG1328	CTP reductase activity
EXW62_RS16375	COG4841	protein insertion into membrane
EXW62_RS16380	COG0824	Thioesterase
EXW62_RS16405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_RS16415	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW62_RS16445	COG2211	Major facilitator Superfamily
EXW62_RS16455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW62_RS16465	COG0183	Belongs to the thiolase family
EXW62_RS16470	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS16475	COG1268	BioY protein
EXW62_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS16490	COG1131	(ABC) transporter
EXW62_RS16495	COG1396	sequence-specific DNA binding
EXW62_RS16530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS16540	COG5002	protein histidine kinase activity
EXW62_RS16550	COG0400	carboxylic ester hydrolase activity
EXW62_RS16560	COG0069	glutamate synthase activity
EXW62_RS16565	COG1902	pentaerythritol trinitrate reductase activity
EXW62_RS16570	COG1329	Transcriptional regulator
EXW62_RS16575	COG0010	Belongs to the arginase family
EXW62_RS16585	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW62_RS16590	COG2986	histidine ammonia-lyase
EXW62_RS16600	COG2226	methyltransferase
EXW62_RS16625	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW62_RS16630	COG0785	Cytochrome C biogenesis protein
EXW62_RS16645	COG1473	amidohydrolase
EXW62_RS16650	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_RS16655	COG1131	(ABC) transporter
EXW62_RS16665	COG0583	DNA-binding transcription factor activity
EXW62_RS16675	COG1346	cytolysis
EXW62_RS16695	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS16695	COG3409	Peptidoglycan-binding domain 1 protein
EXW62_RS16715	COG1132	(ABC) transporter
EXW62_RS16720	COG1132	(ABC) transporter
EXW62_RS16725	COG3763	UPF0154 protein
EXW62_RS16740	COG3639	organic phosphonate transmembrane transporter activity
EXW62_RS16745	COG3639	organic phosphonate transmembrane transporter activity
EXW62_RS16755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS16760	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS16770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW62_RS16775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW62_RS16790	COG1695	Transcriptional regulator
EXW62_RS16795	COG1132	(ABC) transporter
EXW62_RS16825	COG0367	asparagine synthase
EXW62_RS16830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW62_RS16840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW62_RS16850	COG3420	alginic acid biosynthetic process
EXW62_RS16850	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW62_RS16860	COG1442	glycosyl transferase family 8
EXW62_RS16865	COG1442	glycosyl transferase family 8
EXW62_RS16865	COG1216	Glycosyl transferase, family 2
EXW62_RS16880	COG0297	glycogen (starch) synthase activity
EXW62_RS16890	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS16900	COG1215	transferase activity, transferring glycosyl groups
EXW62_RS16905	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS16910	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS16915	COG1086	Polysaccharide biosynthesis protein
EXW62_RS16920	COG0489	protein tyrosine kinase activity
EXW62_RS16925	COG3944	biosynthesis protein
EXW62_RS16930	COG0174	glutamine synthetase
EXW62_RS16935	COG0789	Transcriptional regulator
EXW62_RS16940	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW62_RS16945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW62_RS16950	COG2860	membrane
EXW62_RS16960	COG0464	growth
EXW62_RS16980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW62_RS16990	COG3584	3D domain protein
EXW62_RS16990	COG1388	LysM domain
EXW62_RS16995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_RS16995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_RS16995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS17000	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW62_RS17005	COG1349	DNA-binding transcription factor activity
EXW62_RS17010	COG1979	alcohol dehydrogenase
EXW62_RS17015	COG2322	membrane
EXW62_RS17025	COG1473	amidohydrolase
EXW62_RS17030	COG1408	metallophosphoesterase
EXW62_RS17045	COG2217	Heavy metal translocating P-type atpase
EXW62_RS17050	COG2608	mercury ion transmembrane transporter activity
EXW62_RS17055	COG1937	Protein conserved in bacteria
EXW62_RS17090	COG4566	intracellular signal transduction
EXW62_RS17100	COG2819	hydrolase of the alpha beta superfamily
EXW62_RS17105	COG1120	ATPase activity
EXW62_RS17110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS17115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS17120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS17125	COG0708	Exodeoxyribonuclease III
EXW62_RS17130	COG2169	Transcriptional regulator
EXW62_RS17135	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW62_RS17140	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW62_RS17145	COG2706	6-phosphogluconolactonase activity
EXW62_RS17150	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_RS17155	COG2364	Membrane
EXW62_RS17175	COG0346	lactoylglutathione lyase activity
EXW62_RS17180	COG5001	Diguanylate cyclase
EXW62_RS17180	COG3300	MHYT domain
EXW62_RS17220	COG1346	cytolysis
EXW62_RS17230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW62_RS17235	COG0596	Alpha beta hydrolase
EXW62_RS17235	COG2945	thiolester hydrolase activity
EXW62_RS17240	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW62_RS17250	COG2188	Transcriptional regulator
EXW62_RS17255	COG2723	6-phospho-beta-galactosidase activity
EXW62_RS17260	COG0823	Involved in the tonB-independent uptake of proteins
EXW62_RS17265	COG3773	Cell wall hydrolase
EXW62_RS17275	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW62_RS17290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW62_RS17300	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW62_RS17305	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW62_RS17310	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW62_RS17315	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW62_RS17315	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW62_RS17325	COG2359	stage V sporulation protein S
EXW62_RS17330	COG1692	metallophosphoesterase
EXW62_RS17335	COG1418	mRNA catabolic process
EXW62_RS17340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW62_RS17345	COG1546	Belongs to the CinA family
EXW62_RS17345	COG1058	Belongs to the CinA family
EXW62_RS17350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW62_RS17355	COG1426	Protein conserved in bacteria
EXW62_RS17370	COG0300	oxidoreductase activity
EXW62_RS17375	COG0612	Peptidase, M16
EXW62_RS17380	COG0612	Peptidase, M16
EXW62_RS17385	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW62_RS17390	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW62_RS17395	COG3845	ABC transporter
EXW62_RS17400	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW62_RS17405	COG2188	Transcriptional regulator
EXW62_RS17415	COG1674	ftsk spoiiie
EXW62_RS17425	COG0740	serine-type endopeptidase activity
EXW62_RS17430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_RS17440	COG0527	aspartate kinase activity
EXW62_RS17445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW62_RS17450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW62_RS17455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW62_RS17460	COG1873	PFAM PRC-barrel domain
EXW62_RS17465	COG0612	Peptidase, M16
EXW62_RS17470	COG0726	polysaccharide deacetylase
EXW62_RS17475	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW62_RS17485	COG0196	riboflavin kinase activity
EXW62_RS17495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW62_RS17500	COG1550	Protein conserved in bacteria
EXW62_RS17505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW62_RS17510	COG1358	cellular component organization or biogenesis
EXW62_RS17515	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW62_RS17520	COG0195	Participates in both transcription termination and antitermination
EXW62_RS17545	COG0442	prolyl-tRNA aminoacylation
EXW62_RS17550	COG0750	zinc metalloprotease
EXW62_RS17560	COG4589	Belongs to the CDS family
EXW62_RS17570	COG0233	cytoplasmic translational termination
EXW62_RS17575	COG0528	UMP kinase activity
EXW62_RS17580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW62_RS17585	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW62_RS17590	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW62_RS17595	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW62_RS17600	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW62_RS17605	COG4974	Belongs to the 'phage' integrase family
EXW62_RS17610	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW62_RS17615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_RS17620	COG0758	DNA mediated transformation
EXW62_RS17625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW62_RS17630	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW62_RS17635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW62_RS17650	COG0335	large ribosomal subunit rRNA binding
EXW62_RS17655	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW62_RS17660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW62_RS17665	COG1837	Belongs to the UPF0109 family
EXW62_RS17675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW62_RS17685	COG0552	protein localization to endoplasmic reticulum
EXW62_RS17690	COG1196	nuclear chromosome segregation
EXW62_RS17695	COG0571	ribonuclease III activity
EXW62_RS17700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW62_RS17705	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS17710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW62_RS17715	COG0416	fatty acid biosynthetic process
EXW62_RS17720	COG1349	DNA-binding transcription factor activity
EXW62_RS17720	COG2050	protein possibly involved in aromatic compounds catabolism
EXW62_RS17725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW62_RS17730	COG1461	Dihydroxyacetone kinase
EXW62_RS17735	COG1302	Protein conserved in bacteria
EXW62_RS17750	COG1564	THIamine pyrophosphokinase
EXW62_RS17755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW62_RS17765	COG0515	serine threonine protein kinase
EXW62_RS17765	COG2815	serine threonine protein kinase
EXW62_RS17770	COG0631	protein serine/threonine phosphatase activity
EXW62_RS17775	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW62_RS17780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW62_RS17780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW62_RS17785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW62_RS17790	COG0242	peptide deformylase activity
EXW62_RS17795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW62_RS17800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW62_RS17805	COG1758	RNA polymerase activity
EXW62_RS17820	COG1561	YicC-like family, N-terminal region
EXW62_RS17825	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW62_RS17835	COG0006	proline dipeptidase activity
EXW62_RS17850	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW62_RS17870	COG0167	dihydroorotate dehydrogenase activity
EXW62_RS17875	COG0543	2 iron, 2 sulfur cluster binding
EXW62_RS17880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW62_RS17890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW62_RS17895	COG0540	Belongs to the ATCase OTCase family
EXW62_RS17905	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW62_RS17910	COG0564	pseudouridine synthase activity
EXW62_RS17930	COG3599	regulation of cell shape
EXW62_RS17935	COG2302	S4 RNA-binding domain
EXW62_RS17940	COG0762	integral membrane protein
EXW62_RS17945	COG1799	cell septum assembly
EXW62_RS17950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW62_RS17960	COG1873	PFAM PRC-barrel domain
EXW62_RS17965	COG1191	sigma factor activity
EXW62_RS17970	COG1191	sigma factor activity
EXW62_RS17980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW62_RS17985	COG0849	cell division
EXW62_RS17990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW62_RS18005	COG0772	Belongs to the SEDS family
EXW62_RS18010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW62_RS18015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW62_RS18020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW62_RS18025	COG0768	penicillin binding
EXW62_RS18030	COG0768	penicillin binding
EXW62_RS18040	COG0275	rRNA processing
EXW62_RS18045	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW62_RS18050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW62_RS18055	COG0454	-acetyltransferase
EXW62_RS18065	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW62_RS18070	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW62_RS18075	COG1323	Belongs to the UPF0348 family
EXW62_RS18080	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW62_RS18085	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW62_RS18090	COG3314	Sporulation integral membrane protein YlbJ
EXW62_RS18100	COG0742	ribosomal rna small subunit methyltransferase
EXW62_RS18110	COG4471	UPF0298 protein
EXW62_RS18115	COG3679	Belongs to the UPF0342 family
EXW62_RS18120	COG0406	alpha-ribazole phosphatase activity
EXW62_RS18135	COG2340	Cysteine-rich secretory protein family
EXW62_RS18145	COG3336	cytochrome c oxidase
EXW62_RS18170	COG0109	protoheme IX farnesyltransferase activity
EXW62_RS18175	COG1612	heme a metabolic process
EXW62_RS18180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW62_RS18185	COG0772	Belongs to the SEDS family
EXW62_RS18190	COG4838	Belongs to the UPF0358 family
EXW62_RS18195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW62_RS18200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW62_RS18210	COG4896	Protein conserved in bacteria
EXW62_RS18225	COG1217	gtp-binding protein TYPA
EXW62_RS18235	COG0483	inositol monophosphate 1-phosphatase activity
EXW62_RS18245	COG4493	Belongs to the UPF0637 family
EXW62_RS18250	COG4476	Belongs to the UPF0223 family
EXW62_RS18255	COG1982	Orn Lys Arg decarboxylase major
EXW62_RS18310	COG0022	dehydrogenase e1 component
EXW62_RS18315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW62_RS18325	COG0242	peptide deformylase activity
EXW62_RS18330	COG0561	phosphatase activity
EXW62_RS18335	COG5503	Protein of unknown function (DUF1447)
EXW62_RS18340	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_RS18345	COG0569	domain protein
EXW62_RS18355	COG1473	amidohydrolase
EXW62_RS18360	COG2171	N-acyltransferase activity
EXW62_RS18365	COG0583	DNA-binding transcription factor activity
EXW62_RS18370	COG0517	IMP dehydrogenase activity
EXW62_RS18380	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW62_RS18390	COG4703	Protein of unknown function (DUF1797)
EXW62_RS18405	COG2200	EAL domain
EXW62_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS18415	COG1408	metallophosphoesterase
EXW62_RS18460	COG2814	Major facilitator Superfamily
EXW62_RS18470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW62_RS18480	COG3209	COG3209 Rhs family protein
EXW62_RS18490	COG2205	protein histidine kinase activity
EXW62_RS18500	COG0436	Aminotransferase
EXW62_RS18505	COG1609	Transcriptional regulator
EXW62_RS18510	COG3833	ABC-type maltose transport systems, permease component
EXW62_RS18515	COG1175	transmembrane transport
EXW62_RS18520	COG2182	Extracellular solute-binding protein
EXW62_RS18530	COG0366	Alpha amylase catalytic
EXW62_RS18535	COG3842	ATPase activity
EXW62_RS18580	COG0183	Belongs to the thiolase family
EXW62_RS18615	COG1695	Transcriptional regulator
EXW62_RS18620	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS18630	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW62_RS18640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW62_RS18645	COG0436	Aminotransferase
EXW62_RS18650	COG1850	ribulose-bisphosphate carboxylase activity
EXW62_RS18655	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW62_RS18660	COG0235	Class ii aldolase
EXW62_RS18665	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW62_RS18680	COG2084	Dehydrogenase
EXW62_RS18690	COG2199	diguanylate cyclase activity
EXW62_RS18695	COG0778	Nitroreductase
EXW62_RS18720	COG2190	(PTS) system
EXW62_RS18720	COG1263	PTS System
EXW62_RS18720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW62_RS18725	COG3711	transcriptional antiterminator
EXW62_RS18735	COG2188	Transcriptional regulator
EXW62_RS18740	COG0363	glucosamine-6-phosphate deaminase activity
EXW62_RS18745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW62_RS18755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW62_RS18760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW62_RS18770	COG1547	Domain of unknown function (DUF309)
EXW62_RS18780	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW62_RS18785	COG4086	secreted protein
EXW62_RS18790	COG0561	phosphatase activity
EXW62_RS18795	COG0697	spore germination
EXW62_RS18810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_RS18850	COG1686	Belongs to the peptidase S11 family
EXW62_RS18855	COG1725	Transcriptional regulator
EXW62_RS18860	COG1131	(ABC) transporter
EXW62_RS18880	COG1846	Transcriptional regulator
EXW62_RS18895	COG0598	Magnesium transport protein CorA
EXW62_RS18910	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW62_RS18920	COG4974	Belongs to the 'phage' integrase family
EXW62_RS18930	COG0735	belongs to the Fur family
EXW62_RS18935	COG1300	Membrane
EXW62_RS18955	COG0667	Aldo Keto reductase
EXW62_RS18960	COG0656	L-ascorbic acid biosynthetic process
EXW62_RS18965	COG0456	acetyltransferase
EXW62_RS18965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW62_RS18975	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS18975	COG1525	nuclease
EXW62_RS18975	COG4085	toxin activity
EXW62_RS18980	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW62_RS18990	COG0596	Alpha beta hydrolase
EXW62_RS18995	COG2056	Na+-H+ antiporter family
EXW62_RS19000	COG1609	Transcriptional regulator
EXW62_RS19005	COG0456	acetyltransferase
EXW62_RS19010	COG1073	alpha beta
EXW62_RS19025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW62_RS19025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW62_RS19030	COG0307	riboflavin synthase, alpha
EXW62_RS19035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW62_RS19035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW62_RS19050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW62_RS19055	COG4106	trans-aconitate 2-methyltransferase activity
EXW62_RS19060	COG1073	alpha beta
EXW62_RS19060	COG2226	methyltransferase
EXW62_RS19065	COG0156	8-amino-7-oxononanoate synthase activity
EXW62_RS19075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW62_RS19085	COG1757	Na H antiporter
EXW62_RS19090	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS19100	COG1522	sequence-specific DNA binding
EXW62_RS19120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW62_RS19125	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW62_RS19135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW62_RS19145	COG0300	oxidoreductase activity
EXW62_RS19150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS19155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_RS19160	COG1760	l-serine dehydratase
EXW62_RS19165	COG1760	l-serine dehydratase
EXW62_RS19175	COG1234	tRNA 3'-trailer cleavage
EXW62_RS19190	COG1285	pathogenesis
EXW62_RS19205	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW62_RS19210	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS19225	COG1376	ErfK ybiS ycfS ynhG family protein
EXW62_RS19230	COG4129	membrane
EXW62_RS19235	COG1126	abc transporter atp-binding protein
EXW62_RS19240	COG0765	amino acid transport
EXW62_RS19245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW62_RS19260	COG2816	NAD+ diphosphatase activity
EXW62_RS19265	COG2323	membrane
EXW62_RS19270	COG0772	Belongs to the SEDS family
EXW62_RS19275	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW62_RS19280	COG0022	dehydrogenase e1 component
EXW62_RS19285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW62_RS19290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW62_RS19295	COG3426	butyrate kinase activity
EXW62_RS19305	COG0280	phosphate acetyltransferase
EXW62_RS19310	COG3290	protein histidine kinase activity
EXW62_RS19310	COG3829	transcription factor binding
EXW62_RS19320	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_RS19325	COG3093	addiction module antidote protein HigA
EXW62_RS19375	COG0582	viral genome integration into host DNA
EXW62_RS19425	COG0745	RESPONSE REGULATOR receiver
EXW62_RS19430	COG0750	zinc metalloprotease
EXW62_RS19435	COG0497	DNA recombination
EXW62_RS19440	COG1438	arginine binding
EXW62_RS19445	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW62_RS19450	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW62_RS19455	COG0142	geranyltranstransferase activity
EXW62_RS19460	COG1722	exodeoxyribonuclease VII activity
EXW62_RS19470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW62_RS19475	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW62_RS19480	COG1302	Protein conserved in bacteria
EXW62_RS19485	COG0439	Biotin carboxylase
EXW62_RS19490	COG0511	ligase activity, forming carbon-carbon bonds
EXW62_RS19535	COG3854	ATPases associated with a variety of cellular activities
EXW62_RS19555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW62_RS19560	COG0006	proline dipeptidase activity
EXW62_RS19575	COG3872	metal-dependent enzyme
EXW62_RS19585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW62_RS19620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS19630	COG1609	Transcriptional regulator
EXW62_RS19640	COG2076	Multidrug Resistance protein
EXW62_RS19645	COG2076	Multidrug Resistance protein
EXW62_RS19680	COG1725	Transcriptional regulator
EXW62_RS19695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW62_RS19705	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW62_RS19710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_RS19740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW62_RS19765	COG4970	Tfp pilus assembly protein FimT
EXW62_RS19770	COG4537	Required for transformation and DNA binding
EXW62_RS19775	COG1459	type II secretion system
EXW62_RS19780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW62_RS19835	COG1410	methionine synthase
EXW62_RS19835	COG0646	methionine synthase
EXW62_RS19840	COG0646	methionine synthase
EXW62_RS19840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW62_RS19845	COG0626	cystathionine gamma-synthase activity
EXW62_RS19850	COG0626	cystathionine gamma-synthase activity
EXW62_RS19870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS19880	COG1940	carbohydrate kinase activity
EXW62_RS19885	COG4483	Protein conserved in bacteria
EXW62_RS19890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW62_RS19895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW62_RS19900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW62_RS19905	COG0704	Plays a role in the regulation of phosphate uptake
EXW62_RS19915	COG0581	inorganic phosphate transmembrane transporter activity
EXW62_RS19920	COG0573	inorganic phosphate transmembrane transporter activity
EXW62_RS19925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW62_RS19930	COG0768	penicillin binding
EXW62_RS19935	COG0477	Major facilitator Superfamily
EXW62_RS19940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW62_RS19960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW62_RS19965	COG0735	belongs to the Fur family
EXW62_RS19970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW62_RS19975	COG1121	(ABC) transporter
EXW62_RS19980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS20005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW62_RS20010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW62_RS20015	COG2384	SAM-dependent methyltransferase
EXW62_RS20025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW62_RS20030	COG0358	DNA primase activity
EXW62_RS20035	COG1671	Belongs to the UPF0178 family
EXW62_RS20040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW62_RS20045	COG0517	IMP dehydrogenase activity
EXW62_RS20050	COG1381	Involved in DNA repair and RecF pathway recombination
EXW62_RS20060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW62_RS20065	COG0295	cytidine deaminase activity
EXW62_RS20070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW62_RS20075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW62_RS20080	COG1480	7TM receptor with intracellular HD hydrolase
EXW62_RS20085	COG1702	phosphate starvation-inducible protein PhoH
EXW62_RS20100	COG1610	YqeY-like protein
EXW62_RS20105	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW62_RS20110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW62_RS20115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW62_RS20125	COG0484	heat shock protein binding
EXW62_RS20130	COG0443	Heat shock 70 kDa protein
EXW62_RS20140	COG1420	regulation of RNA biosynthetic process
EXW62_RS20145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW62_RS20150	COG1733	regulation of RNA biosynthetic process
EXW62_RS20155	COG0481	GTPase activity
EXW62_RS20165	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW62_RS20170	COG0268	Binds directly to 16S ribosomal RNA
EXW62_RS20175	COG1466	dna polymerase III delta subunit
EXW62_RS20185	COG0658	competence protein
EXW62_RS20185	COG2333	competence protein COMEC
EXW62_RS20190	COG2131	deaminase
EXW62_RS20195	COG1555	photosystem II stabilization
EXW62_RS20195	COG1596	polysaccharide export
EXW62_RS20200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW62_RS20205	COG2226	methyltransferase
EXW62_RS20210	COG0799	negative regulation of ribosome biogenesis
EXW62_RS20215	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW62_RS20220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW62_RS20225	COG1534	Rna-binding protein
EXW62_RS20230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW62_RS20235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW62_RS20240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW62_RS20250	COG0688	phosphatidylethanolamine metabolic process
EXW62_RS20270	COG2357	RelA SpoT domain protein
EXW62_RS20280	COG1785	Belongs to the alkaline phosphatase family
EXW62_RS20290	COG2267	carboxylic ester hydrolase activity
EXW62_RS20325	COG1404	Belongs to the peptidase S8 family
EXW62_RS20330	COG3186	Phenylalanine-4-hydroxylase
EXW62_RS20335	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW62_RS20340	COG2514	catechol 2,3-dioxygenase activity
EXW62_RS20345	COG2259	Doxx family
EXW62_RS20385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW62_RS20395	COG1454	alcohol dehydrogenase
EXW62_RS20395	COG1012	belongs to the aldehyde dehydrogenase family
EXW62_RS20400	COG0626	cystathionine gamma-synthase activity
EXW62_RS20405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW62_RS20410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_RS20415	COG2226	methyltransferase
EXW62_RS20430	COG0768	penicillin binding
EXW62_RS20435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW62_RS20440	COG0572	uridine kinase
EXW62_RS20445	COG0826	peptidase U32
EXW62_RS20450	COG0826	peptidase U32
EXW62_RS20455	COG4122	O-methyltransferase activity
EXW62_RS20460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW62_RS20470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW62_RS20480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW62_RS20485	COG0628	permease
EXW62_RS20505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW62_RS20515	COG0482	sulfurtransferase activity
EXW62_RS20520	COG1104	cysteine desulfurase activity
EXW62_RS20525	COG1959	2 iron, 2 sulfur cluster binding
EXW62_RS20530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW62_RS20540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW62_RS20545	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW62_RS20560	COG1490	D-aminoacyl-tRNA deacylase activity
EXW62_RS20565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW62_RS20570	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW62_RS20575	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW62_RS20575	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW62_RS20580	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW62_RS20585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW62_RS20585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW62_RS20595	COG2244	polysaccharide biosynthetic process
EXW62_RS20600	COG2323	membrane
EXW62_RS20610	COG1862	Preprotein translocase
EXW62_RS20615	COG0343	queuine tRNA-ribosyltransferase activity
EXW62_RS20630	COG2255	four-way junction helicase activity
EXW62_RS20635	COG0632	four-way junction helicase activity
EXW62_RS20640	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW62_RS20665	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW62_RS20670	COG0157	Belongs to the NadC ModD family
EXW62_RS20675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW62_RS20680	COG1104	cysteine desulfurase activity
EXW62_RS20685	COG1827	regulation of RNA biosynthetic process
EXW62_RS20695	COG2258	MOSC domain
EXW62_RS20705	COG0077	Prephenate dehydratase
EXW62_RS20710	COG0577	efflux transmembrane transporter activity
EXW62_RS20715	COG0577	efflux transmembrane transporter activity
EXW62_RS20720	COG1136	(ABC) transporter
EXW62_RS20725	COG5002	protein histidine kinase activity
EXW62_RS20730	COG0745	RESPONSE REGULATOR receiver
EXW62_RS20735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW62_RS20740	COG3290	protein histidine kinase activity
EXW62_RS20750	COG2868	ribosomal protein
EXW62_RS20760	COG1530	ribonuclease E activity
EXW62_RS20765	COG1994	Peptidase M50
EXW62_RS20770	COG0739	heme binding
EXW62_RS20775	COG2894	cell division
EXW62_RS20780	COG0850	regulation of cytokinetic process
EXW62_RS20790	COG1792	Involved in formation and maintenance of cell shape
EXW62_RS20795	COG1077	Cell shape determining protein MreB Mrl
EXW62_RS20800	COG2003	Belongs to the UPF0758 family
EXW62_RS20805	COG0424	maF-like protein
EXW62_RS20815	COG0285	dihydrofolate synthase activity
EXW62_RS20835	COG1388	LysM domain
EXW62_RS20840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW62_RS20845	COG0113	porphobilinogen synthase activity
EXW62_RS20850	COG1587	Uroporphyrinogen-III synthase
EXW62_RS20855	COG0181	hydroxymethylbilane synthase activity
EXW62_RS20860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW62_RS20865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW62_RS20870	COG1846	Transcriptional regulator
EXW62_RS20875	COG1764	response to oxidative stress
EXW62_RS20880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW62_RS20890	COG0470	DNA polymerase III
EXW62_RS20890	COG1067	ATP-dependent peptidase activity
EXW62_RS20900	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW62_RS20930	COG0622	Phosphoesterase
EXW62_RS20940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW62_RS20945	COG5401	PFAM Sporulation and spore germination
EXW62_RS20960	COG2197	response regulator
EXW62_RS20965	COG2233	PERMEase
EXW62_RS20970	COG0402	S-adenosylhomocysteine deaminase activity
EXW62_RS20975	COG1983	PspC domain protein
EXW62_RS20980	COG1396	sequence-specific DNA binding
EXW62_RS20985	COG0697	spore germination
EXW62_RS20995	COG1959	2 iron, 2 sulfur cluster binding
EXW62_RS21000	COG1668	transmembrane transport
EXW62_RS21005	COG4152	abc transporter atp-binding protein
EXW62_RS21010	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW62_RS21015	COG1360	Flagellar Motor Protein
EXW62_RS21020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW62_RS21025	COG1876	peptidase activity
EXW62_RS21030	COG0824	Thioesterase
EXW62_RS21035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW62_RS21040	COG1053	succinate dehydrogenase
EXW62_RS21045	COG2009	succinate dehydrogenase
EXW62_RS21050	COG1719	4-vinyl reductase, 4VR
EXW62_RS21055	COG0322	excinuclease ABC activity
EXW62_RS21060	COG3118	belongs to the thioredoxin family
EXW62_RS21065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW62_RS21070	COG2086	electron transfer activity
EXW62_RS21075	COG1024	Enoyl-CoA hydratase
EXW62_RS21080	COG1309	transcriptional regulator
EXW62_RS21085	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS21105	COG2318	DinB family
EXW62_RS21130	COG1131	(ABC) transporter
EXW62_RS21135	COG2205	protein histidine kinase activity
EXW62_RS21140	COG0745	RESPONSE REGULATOR receiver
EXW62_RS21150	COG4895	conserved protein (DUF2196)
EXW62_RS21155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW62_RS21165	COG4509	Sortase family
EXW62_RS21170	COG1120	ATPase activity
EXW62_RS21185	COG5386	Cell surface protein
EXW62_RS21195	COG5386	Cell surface protein
EXW62_RS21200	COG1114	Component of the transport system for branched-chain amino acids
EXW62_RS21205	COG1187	pseudouridine synthase activity
EXW62_RS21210	COG1193	negative regulation of DNA recombination
EXW62_RS21215	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW62_RS21215	COG1796	DNA polymerase
EXW62_RS21220	COG1286	toxin biosynthetic process
EXW62_RS21225	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW62_RS21230	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW62_RS21255	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW62_RS21260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW62_RS21270	COG1418	mRNA catabolic process
EXW62_RS21280	COG2814	Major facilitator Superfamily
EXW62_RS21285	COG1566	PFAM secretion protein HlyD family protein
EXW62_RS21290	COG1309	transcriptional regulator
EXW62_RS21295	COG1363	Peptidase, m42
EXW62_RS21305	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW62_RS21320	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW62_RS21330	COG1484	DNA-dependent DNA replication
EXW62_RS21335	COG3611	Membrane attachment protein
EXW62_RS21340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW62_RS21345	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW62_RS21350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW62_RS21360	COG1971	Probably functions as a manganese efflux pump
EXW62_RS21370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_RS21370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW62_RS21375	COG5002	protein histidine kinase activity
EXW62_RS21380	COG0745	RESPONSE REGULATOR receiver
EXW62_RS21400	COG0538	isocitrate dehydrogenase activity
EXW62_RS21405	COG0372	Belongs to the citrate synthase family
EXW62_RS21415	COG0628	permease
EXW62_RS21420	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW62_RS21430	COG0205	6-phosphofructokinase activity
EXW62_RS21445	COG1725	Transcriptional regulator
EXW62_RS21450	COG0281	malic enzyme
EXW62_RS21455	COG0587	DNA-directed DNA polymerase activity
EXW62_RS21470	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW62_RS21485	COG4109	DRTGG domain
EXW62_RS21495	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW62_RS21500	COG0006	proline dipeptidase activity
EXW62_RS21535	COG1476	TRANSCRIPTIONal
EXW62_RS21550	COG1028	Short-chain dehydrogenase reductase Sdr
EXW62_RS21555	COG0589	response to stress
EXW62_RS21575	COG0165	Argininosuccinate lyase
EXW62_RS21580	COG0137	argininosuccinate synthase activity
EXW62_RS21595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS21610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW62_RS21615	COG0827	DNA restriction-modification system
EXW62_RS21620	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW62_RS21625	COG3874	Sporulation protein YtfJ
EXW62_RS21640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW62_RS21650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_RS21665	COG1104	cysteine desulfurase activity
EXW62_RS21670	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW62_RS21685	COG1309	transcriptional regulator
EXW62_RS21690	COG1956	GAF domain-containing protein
EXW62_RS21695	COG0626	cystathionine gamma-synthase activity
EXW62_RS21700	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW62_RS21730	COG1595	DNA-templated transcription, initiation
EXW62_RS21740	COG0110	maltose O-acetyltransferase activity
EXW62_RS21745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW62_RS21750	COG0454	-acetyltransferase
EXW62_RS21755	COG0517	IMP dehydrogenase activity
EXW62_RS21760	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW62_RS21785	COG5002	protein histidine kinase activity
EXW62_RS21790	COG0666	response to abiotic stimulus
EXW62_RS21800	COG1970	mechanosensitive ion channel activity
EXW62_RS21820	COG1609	Transcriptional regulator
EXW62_RS21825	COG4851	CamS sex pheromone cAM373 precursor
EXW62_RS21830	COG3118	belongs to the thioredoxin family
EXW62_RS21840	COG2309	aminopeptidase activity
EXW62_RS21860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS21865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW62_RS21875	COG1674	ftsk spoiiie
EXW62_RS21890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_RS21895	COG4848	Belongs to the UPF0354 family
EXW62_RS21900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_RS21905	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW62_RS21910	COG1363	Peptidase, m42
EXW62_RS21920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS21925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW62_RS21935	COG0510	thiamine kinase activity
EXW62_RS21940	COG1523	belongs to the glycosyl hydrolase 13 family
EXW62_RS21950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW62_RS21955	COG1349	DNA-binding transcription factor activity
EXW62_RS21960	COG1187	pseudouridine synthase activity
EXW62_RS21965	COG2244	polysaccharide biosynthetic process
EXW62_RS21970	COG2081	HI0933 family
EXW62_RS21975	COG2814	Major facilitator Superfamily
EXW62_RS21985	COG3832	glyoxalase III activity
EXW62_RS22005	COG1329	Transcriptional regulator
EXW62_RS22030	COG0314	molybdopterin synthase activity
EXW62_RS22035	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW62_RS22040	COG0303	'Molybdopterin
EXW62_RS22045	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW62_RS22050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW62_RS22055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW62_RS22075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW62_RS22085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW62_RS22125	COG0495	leucyl-tRNA aminoacylation
EXW62_RS22130	COG2814	Major facilitator Superfamily
EXW62_RS22135	COG0475	glutathione-regulated potassium exporter activity
EXW62_RS22140	COG0490	domain, Protein
EXW62_RS22145	COG0582	viral genome integration into host DNA
EXW62_RS22155	COG1136	(ABC) transporter
EXW62_RS22175	COG1242	4 iron, 4 sulfur cluster binding
EXW62_RS22180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW62_RS22185	COG1794	racemase activity, acting on amino acids and derivatives
EXW62_RS22200	COG2267	carboxylic ester hydrolase activity
EXW62_RS22205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW62_RS22210	COG0671	phosphoesterase, PA-phosphatase related
EXW62_RS22215	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS22225	COG1404	Belongs to the peptidase S8 family
EXW62_RS22230	COG2197	response regulator
EXW62_RS22235	COG4585	Histidine kinase
EXW62_RS22240	COG0746	molybdenum cofactor guanylyltransferase activity
EXW62_RS22260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW62_RS22265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW62_RS22295	COG5002	protein histidine kinase activity
EXW62_RS22300	COG3852	Histidine kinase
EXW62_RS22305	COG0753	catalase activity
EXW62_RS22310	COG2267	carboxylic ester hydrolase activity
EXW62_RS22315	COG1368	sulfuric ester hydrolase activity
EXW62_RS22370	COG1278	Cold shock
EXW62_RS22380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW62_RS22385	COG1116	anion transmembrane transporter activity
EXW62_RS22390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW62_RS22410	COG0494	nUDIX hydrolase
EXW62_RS22455	COG0288	reversible hydration of carbon dioxide
EXW62_RS22460	COG1271	oxidase subunit
EXW62_RS22465	COG1294	oxidase, subunit
EXW62_RS22480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS22510	COG1842	Phage shock protein A
EXW62_RS22535	COG3859	Proton-coupled thiamine transporter YuaJ
EXW62_RS22540	COG5002	protein histidine kinase activity
EXW62_RS22545	COG0745	RESPONSE REGULATOR receiver
EXW62_RS22575	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW62_RS22580	COG1597	lipid kinase activity
EXW62_RS22615	COG1136	(ABC) transporter
EXW62_RS22645	COG5002	protein histidine kinase activity
EXW62_RS22665	COG0577	efflux transmembrane transporter activity
EXW62_RS22670	COG1136	(ABC) transporter
EXW62_RS22675	COG3708	Transcriptional regulator
EXW62_RS22675	COG2207	Transcriptional regulator
EXW62_RS22685	COG1131	(ABC) transporter
EXW62_RS22690	COG5658	integral membrane protein
EXW62_RS22695	COG0640	Transcriptional regulator
EXW62_RS22700	COG0745	RESPONSE REGULATOR receiver
EXW62_RS22705	COG2205	protein histidine kinase activity
EXW62_RS22710	COG0577	efflux transmembrane transporter activity
EXW62_RS22715	COG0577	efflux transmembrane transporter activity
EXW62_RS22720	COG1136	(ABC) transporter
EXW62_RS22725	COG0577	efflux transmembrane transporter activity
EXW62_RS22740	COG2188	Transcriptional regulator
EXW62_RS22760	COG3964	amidohydrolase
EXW62_RS22780	COG4948	Mandelate Racemase Muconate Lactonizing
EXW62_RS22785	COG0318	PFAM AMP-dependent synthetase and ligase
EXW62_RS22790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW62_RS22795	COG0596	Alpha beta hydrolase
EXW62_RS22800	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW62_RS22805	COG1169	isochorismate synthase
EXW62_RS22810	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW62_RS22815	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW62_RS22820	COG1278	Cold shock
EXW62_RS22840	COG0058	SHG alpha-glucan phosphorylase activity
EXW62_RS22850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW62_RS22855	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW62_RS22860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW62_RS23010	COG1285	pathogenesis
EXW62_RS23015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW62_RS23025	COG0166	Belongs to the GPI family
EXW62_RS23030	COG2155	Conserved Protein
EXW62_RS23035	COG1098	S1 RNA binding domain
EXW62_RS23040	COG0436	Aminotransferase
EXW62_RS23045	COG1522	sequence-specific DNA binding
EXW62_RS23050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW62_RS23055	COG2267	carboxylic ester hydrolase activity
EXW62_RS23065	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW62_RS23085	COG5018	Exonuclease
EXW62_RS23090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_RS23110	COG2050	protein possibly involved in aromatic compounds catabolism
EXW62_RS23120	COG1268	BioY protein
EXW62_RS23125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_RS23130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW62_RS23140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW62_RS23145	COG3584	3D domain protein
EXW62_RS23160	COG1252	NADH dehydrogenase
EXW62_RS23165	COG0492	ferredoxin-NADP+ reductase activity
EXW62_RS23170	COG3708	Transcriptional regulator
EXW62_RS23185	COG1683	Conserved Protein
EXW62_RS23200	COG0316	Belongs to the HesB IscA family
EXW62_RS23205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW62_RS23210	COG4844	belongs to the
EXW62_RS23215	COG1252	NADH dehydrogenase
EXW62_RS23225	COG2274	protein secretion by the type I secretion system
EXW62_RS23230	COG0390	transport system, permease component
EXW62_RS23235	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW62_RS23265	COG4837	Protein of unknown function (DUF1462)
EXW62_RS23270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW62_RS23285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_RS23290	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW62_RS23300	COG0647	UMP catabolic process
EXW62_RS23310	COG2445	Protein of unknown function DUF86
EXW62_RS23315	COG1494	fructose-1,6-bisphosphatase
EXW62_RS23335	COG4470	Protein conserved in bacteria
EXW62_RS23350	COG0789	Transcriptional regulator
EXW62_RS23355	COG4377	Putative membrane peptidase family (DUF2324)
EXW62_RS23380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW62_RS23385	COG0739	heme binding
EXW62_RS23395	COG3377	Domain of unknown function (DUF1805)
EXW62_RS23400	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS23405	COG0719	Fe-S assembly protein
EXW62_RS23410	COG0822	iron-sulfur transferase activity
EXW62_RS23415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW62_RS23420	COG0719	Fe-S assembly protein
EXW62_RS23425	COG0396	ATPase activity
EXW62_RS23430	COG1464	Belongs to the NlpA lipoprotein family
EXW62_RS23435	COG1464	Belongs to the NlpA lipoprotein family
EXW62_RS23440	COG2011	ABC-type metal ion transport system permease component
EXW62_RS23455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW62_RS23460	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW62_RS23470	COG0509	glycine decarboxylation via glycine cleavage system
EXW62_RS23475	COG1393	Belongs to the ArsC family
EXW62_RS23510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS23515	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS23520	COG0183	Belongs to the thiolase family
EXW62_RS23525	COG1024	Enoyl-CoA hydratase
EXW62_RS23525	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW62_RS23535	COG1686	Belongs to the peptidase S11 family
EXW62_RS23540	COG0506	proline dehydrogenase activity
EXW62_RS23550	COG0011	TIGRFAM Protein of
EXW62_RS23555	COG0840	transmembrane signaling receptor activity
EXW62_RS23570	COG2814	Major facilitator Superfamily
EXW62_RS23575	COG0531	amino acid
EXW62_RS23595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW62_RS23625	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS23635	COG1376	ErfK ybiS ycfS ynhG family protein
EXW62_RS23640	COG0745	RESPONSE REGULATOR receiver
EXW62_RS23645	COG5002	protein histidine kinase activity
EXW62_RS23655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW62_RS23665	COG0840	transmembrane signaling receptor activity
EXW62_RS23675	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW62_RS23680	COG3227	Zinc metalloprotease (Elastase)
EXW62_RS23700	COG0586	Pfam SNARE associated Golgi protein
EXW62_RS23705	COG0475	glutathione-regulated potassium exporter activity
EXW62_RS23710	COG0490	domain, Protein
EXW62_RS23715	COG1115	amino acid carrier protein
EXW62_RS23720	COG0783	Belongs to the Dps family
EXW62_RS23730	COG2318	DinB family
EXW62_RS23735	COG1611	Belongs to the LOG family
EXW62_RS23745	COG1528	Iron-storage protein
EXW62_RS23750	COG2311	Membrane
EXW62_RS23755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS23760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS23765	COG1115	amino acid carrier protein
EXW62_RS23770	COG2910	NAD(P)H-binding
EXW62_RS23780	COG0656	L-ascorbic acid biosynthetic process
EXW62_RS23785	COG2814	Major facilitator Superfamily
EXW62_RS23790	COG1733	regulation of RNA biosynthetic process
EXW62_RS23800	COG1252	NADH dehydrogenase
EXW62_RS23820	COG0840	transmembrane signaling receptor activity
EXW62_RS23820	COG3290	protein histidine kinase activity
EXW62_RS23830	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW62_RS23850	COG3655	Transcriptional regulator
EXW62_RS23865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW62_RS23880	COG1522	sequence-specific DNA binding
EXW62_RS23885	COG0288	reversible hydration of carbon dioxide
EXW62_RS23890	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW62_RS23895	COG2233	PERMEase
EXW62_RS23920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS23935	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW62_RS23940	COG0557	exoribonuclease II activity
EXW62_RS23945	COG1647	Serine aminopeptidase, S33
EXW62_RS23950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW62_RS23955	COG1346	cytolysis
EXW62_RS23980	COG0149	triose-phosphate isomerase activity
EXW62_RS23985	COG0126	phosphoglycerate kinase activity
EXW62_RS23990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW62_RS24005	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW62_RS24030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW62_RS24045	COG2323	membrane
EXW62_RS24055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS24060	COG1481	regulation of sporulation
EXW62_RS24065	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW62_RS24070	COG1660	Displays ATPase and GTPase activities
EXW62_RS24075	COG1051	belongs to the nudix hydrolase family
EXW62_RS24085	COG0492	ferredoxin-NADP+ reductase activity
EXW62_RS24090	COG0457	Tetratricopeptide repeat
EXW62_RS24095	COG0110	maltose O-acetyltransferase activity
EXW62_RS24100	COG0546	phosphoglycolate phosphatase activity
EXW62_RS24105	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW62_RS24110	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW62_RS24115	COG1950	PFAM Membrane protein of
EXW62_RS24120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW62_RS24135	COG0789	Transcriptional regulator
EXW62_RS24170	COG0583	DNA-binding transcription factor activity
EXW62_RS24175	COG0789	Transcriptional regulator
EXW62_RS24180	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW62_RS24185	COG0488	(ABC) transporter
EXW62_RS24195	COG1132	(ABC) transporter
EXW62_RS24200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_RS24205	COG0793	Belongs to the peptidase S41A family
EXW62_RS24205	COG3409	Peptidoglycan-binding domain 1 protein
EXW62_RS24210	COG2177	Part of the ABC transporter FtsEX involved in
EXW62_RS24215	COG2884	Cell division ATP-binding protein ftsE
EXW62_RS24245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EXW62_RS24250	COG1278	Cold shock
EXW62_RS24255	COG1040	competence protein
EXW62_RS24260	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW62_RS24265	COG0791	NLP P60 protein
EXW62_RS24265	COG1388	LysM domain
EXW62_RS24270	COG1733	regulation of RNA biosynthetic process
EXW62_RS24275	COG1307	EDD domain protein, DegV family
EXW62_RS24280	COG1739	Uncharacterized protein family UPF0029
EXW62_RS24285	COG1316	TRANSCRIPTIONal
EXW62_RS24290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW62_RS24295	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW62_RS24300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW62_RS24310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW62_RS24310	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW62_RS24330	COG1486	melibiose metabolic process
EXW62_RS24335	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_RS24340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_RS24350	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW62_RS24360	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW62_RS24370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW62_RS24375	COG1301	dicarboxylic acid transport
EXW62_RS24390	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW62_RS24400	COG1271	oxidase subunit
EXW62_RS24405	COG1294	oxidase, subunit
EXW62_RS24410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW62_RS24415	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW62_RS24420	COG1620	l-lactate permease
EXW62_RS24430	COG2389	metal-binding protein
EXW62_RS24440	COG1368	sulfuric ester hydrolase activity
EXW62_RS24450	COG0791	NLP P60 protein
EXW62_RS24450	COG1388	LysM domain
EXW62_RS24455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW62_RS24465	COG1215	transferase activity, transferring glycosyl groups
EXW62_RS24470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW62_RS24475	COG3584	3D domain protein
EXW62_RS24475	COG1388	LysM domain
EXW62_RS24500	COG4715	Zinc finger, swim domain protein
EXW62_RS24505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW62_RS24550	COG0577	efflux transmembrane transporter activity
EXW62_RS24555	COG1136	(ABC) transporter
EXW62_RS24580	COG5002	protein histidine kinase activity
EXW62_RS24580	COG3850	Histidine kinase
EXW62_RS24585	COG0745	RESPONSE REGULATOR receiver
EXW62_RS24590	COG1482	cell wall glycoprotein biosynthetic process
EXW62_RS24595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_RS24595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW62_RS24595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS24600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW62_RS24600	COG3711	transcriptional antiterminator
EXW62_RS24605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW62_RS24620	COG1482	cell wall glycoprotein biosynthetic process
EXW62_RS24645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW62_RS24650	COG2244	polysaccharide biosynthetic process
EXW62_RS24655	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW62_RS24660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW62_RS24665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_RS24670	COG4464	protein tyrosine phosphatase activity
EXW62_RS24675	COG0489	protein tyrosine kinase activity
EXW62_RS24680	COG3944	biosynthesis protein
EXW62_RS24685	COG0489	protein tyrosine kinase activity
EXW62_RS24700	COG1609	Transcriptional regulator
EXW62_RS24710	COG0739	heme binding
EXW62_RS24725	COG3279	Response regulator of the LytR AlgR family
EXW62_RS24730	COG2385	sporulation resulting in formation of a cellular spore
EXW62_RS24745	COG4836	Membrane
EXW62_RS24750	COG1007	ATP synthesis coupled electron transport
EXW62_RS24760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW62_RS24765	COG0713	ATP synthesis coupled electron transport
EXW62_RS24770	COG0839	Belongs to the complex I subunit 6 family
EXW62_RS24780	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW62_RS24785	COG0649	NAD binding
EXW62_RS24790	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_RS24795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_RS24800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW62_RS24805	COG3300	MHYT domain
EXW62_RS24805	COG5001	Diguanylate cyclase
EXW62_RS24820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW62_RS24825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW62_RS24830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW62_RS24840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW62_RS24845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW62_RS24855	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW62_RS24890	COG0698	ribose 5-phosphate isomerase
EXW62_RS24900	COG2190	(PTS) system
EXW62_RS24905	COG2259	Doxx family
EXW62_RS24910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW62_RS24920	COG1971	Probably functions as a manganese efflux pump
EXW62_RS24925	COG0009	L-threonylcarbamoyladenylate synthase
EXW62_RS24940	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW62_RS24945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW62_RS24950	COG1435	thymidine kinase activity
EXW62_RS24960	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW62_RS24965	COG1494	fructose-1,6-bisphosphatase
EXW62_RS24985	COG4821	SIS domain
EXW62_RS24990	COG0504	CTP synthase activity
EXW62_RS24995	COG3343	RNA polymerase activity
EXW62_RS25005	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS25010	COG1960	acyl-CoA dehydrogenase activity
EXW62_RS25015	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW62_RS25020	COG0183	Belongs to the thiolase family
EXW62_RS25025	COG2181	nitrate reductase activity
EXW62_RS25025	COG0247	lactate metabolic process
EXW62_RS25030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW62_RS25035	COG4294	response to UV
EXW62_RS25040	COG3300	MHYT domain
EXW62_RS25040	COG5001	Diguanylate cyclase
EXW62_RS25055	COG3227	Zinc metalloprotease (Elastase)
EXW62_RS25060	COG2197	response regulator
EXW62_RS25065	COG4585	Histidine kinase
EXW62_RS25070	COG0842	Transport permease protein
EXW62_RS25075	COG1131	(ABC) transporter
EXW62_RS25080	COG0024	Methionine aminopeptidase
EXW62_RS25090	COG2234	aminopeptidase activity
EXW62_RS25105	COG4506	Protein conserved in bacteria
EXW62_RS25110	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW62_RS25135	COG2814	Major facilitator Superfamily
EXW62_RS25140	COG0789	Transcriptional regulator
EXW62_RS25145	COG0584	glycerophosphoryl diester phosphodiesterase
EXW62_RS25150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW62_RS25160	COG1994	Peptidase M50
EXW62_RS25170	COG1078	dGTPase activity
EXW62_RS25175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW62_RS25180	COG1120	ATPase activity
EXW62_RS25185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS25190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW62_RS25210	COG0280	phosphate acetyltransferase
EXW62_RS25215	COG3253	May function as heme-dependent peroxidase
EXW62_RS25225	COG3773	Cell wall hydrolase
EXW62_RS25235	COG2363	Small membrane protein
EXW62_RS25250	COG2233	PERMEase
EXW62_RS25255	COG0561	phosphatase activity
EXW62_RS25260	COG2814	Major facilitator Superfamily
EXW62_RS25265	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW62_RS25270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW62_RS25275	COG1131	(ABC) transporter
EXW62_RS25280	COG2755	lipolytic protein G-D-S-L family
EXW62_RS25285	COG1609	Transcriptional regulator
EXW62_RS25295	COG0460	homoserine dehydrogenase
EXW62_RS25300	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW62_RS25305	COG2873	o-acetylhomoserine
EXW62_RS25320	COG2197	response regulator
EXW62_RS25325	COG2203	Gaf domain
EXW62_RS25325	COG4585	Histidine kinase
EXW62_RS25330	COG0351	phosphomethylpyrimidine kinase
EXW62_RS25335	COG3706	GGDEF domain
EXW62_RS25340	COG2879	small protein
EXW62_RS25345	COG1966	Carbon starvation protein
EXW62_RS25350	COG3279	Response regulator of the LytR AlgR family
EXW62_RS25355	COG0477	Major facilitator Superfamily
EXW62_RS25380	COG0840	transmembrane signaling receptor activity
EXW62_RS25390	COG1607	acyl-coa hydrolase
EXW62_RS25395	COG1216	Glycosyl transferase, family 2
EXW62_RS25405	COG1216	Glycosyl transferase, family 2
EXW62_RS25415	COG4485	Bacterial membrane protein, YfhO
EXW62_RS25420	COG0463	Glycosyl transferase, family 2
EXW62_RS25430	COG1309	transcriptional regulator
EXW62_RS25435	COG0488	(ABC) transporter
EXW62_RS25440	COG1309	transcriptional regulator
EXW62_RS25445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW62_RS25450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_RS25450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW62_RS25455	COG0628	permease
EXW62_RS25465	COG3279	Response regulator of the LytR AlgR family
EXW62_RS25470	COG3275	phosphorelay sensor kinase activity
EXW62_RS25480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW62_RS25485	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW62_RS25535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW62_RS25540	COG1272	protein, Hemolysin III
EXW62_RS25565	COG1164	Oligoendopeptidase f
EXW62_RS25580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW62_RS25590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW62_RS25595	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW62_RS25600	COG4853	Protein conserved in bacteria
EXW62_RS25610	COG5002	protein histidine kinase activity
EXW62_RS25615	COG0745	RESPONSE REGULATOR receiver
EXW62_RS25645	COG0305	Participates in initiation and elongation during chromosome replication
EXW62_RS25655	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW62_RS25660	COG4241	membrane
EXW62_RS25670	COG0629	single-stranded DNA binding
EXW62_RS25675	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW62_RS25680	COG0012	GTP binding
EXW62_RS25685	COG4481	Protein conserved in bacteria
EXW62_RS25690	COG0668	transmembrane transport
EXW62_RS25700	COG1475	DNA binding
EXW62_RS25705	COG1192	Involved in chromosome partitioning
EXW62_RS25710	COG1475	DNA binding
EXW62_RS25720	COG0445	tRNA wobble uridine modification
EXW62_RS25725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW62_RS25730	COG1847	R3H domain protein
EXW62_RS25735	COG0706	membrane insertase activity
EXW62_RS25740	COG0594	ribonuclease P activity
EXW62_RS25745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW62_RS25800	COG1278	Cold shock
EXW62_RS25885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW62_RS25885	COG0551	DNA topoisomerase type I activity
EXW62_RS25930	COG0463	Glycosyl transferase, family 2
EXW62_RS25955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW62_RS25960	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW62_RS25965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW62_RS25970	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS25985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_RS25990	COG0438	transferase activity, transferring glycosyl groups
EXW62_RS25995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW62_RS26090	COG3773	Cell wall hydrolase
EXW62_RS26175	COG4974	Belongs to the 'phage' integrase family
EXW62_RS26200	COG1388	LysM domain
EXW62_RS26220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW62_RS26240	COG0825	malonyl-CoA metabolic process
EXW62_RS26255	COG1846	Transcriptional regulator
EXW62_RS26265	COG4166	transmembrane transport
EXW62_RS26285	COG1192	Involved in chromosome partitioning
EXW62_RS26305	COG5002	protein histidine kinase activity
EXW62_RS26365	COG3344	reverse transcriptase
EXW62_RS26370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW62_RS26415	COG0737	Belongs to the 5'-nucleotidase family
EXW62_RS26515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW62_RS26570	COG0739	heme binding
EXW62_RS26605	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW62_RS26680	COG1595	DNA-templated transcription, initiation
EXW62_RS26685	COG1403	HNH endonuclease
EXW62_RS26860	COG1609	Transcriptional regulator
EXW62_RS26865	COG2814	Major facilitator Superfamily
EXW62_RS26870	COG0673	inositol 2-dehydrogenase activity
EXW62_RS26895	COG0191	fructose-bisphosphate aldolase activity
EXW62_RS26900	COG3718	enzyme involved in inositol metabolism
EXW62_RS26925	COG2304	oxidoreductase activity
EXW62_RS26950	COG1923	regulation of RNA biosynthetic process
EXW62_RS26960	COG1132	(ABC) transporter
EXW62_RS26980	COG1595	DNA-templated transcription, initiation
EXW62_RS27025	COG2207	Transcriptional regulator
EXW62_RS27065	COG2207	Transcriptional regulator
EXW62_RS27115	COG3338	carbonate dehydratase activity
EXW62_RS27125	COG5002	protein histidine kinase activity
EXW62_RS27155	COG4974	Belongs to the 'phage' integrase family
EXW62_RS27170	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW62_RS27180	COG0814	amino acid
EXW62_RS27185	COG1760	l-serine dehydratase
EXW62_RS27190	COG1760	l-serine dehydratase
EXW62_RS27205	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EXW62_RS27220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EXW62_RS27280	COG0840	transmembrane signaling receptor activity
EXW62_RS27305	COG0457	Tetratricopeptide repeat
EXW62_RS27310	COG3227	Zinc metalloprotease (Elastase)
EXW62_RS27375	COG1136	(ABC) transporter
EXW62_RS27380	COG5002	protein histidine kinase activity
EXW62_RS27385	COG0745	RESPONSE REGULATOR receiver
EXW62_RS27400	COG2378	regulation of single-species biofilm formation
EXW62_RS27405	COG2318	DinB family
EXW62_RS27415	COG4689	acetoacetate decarboxylase
EXW62_RS27420	COG0583	DNA-binding transcription factor activity
EXW62_RS27440	COG0825	malonyl-CoA metabolic process
EXW62_RS27475	COG1309	transcriptional regulator
EXW62_RS27545	COG4565	transcriptional regulatory protein
EXW62_RS27550	COG3290	protein histidine kinase activity
EXW62_RS27590	COG0753	catalase activity
EXW62_RS27700	COG0686	Belongs to the AlaDH PNT family
EXW62_RS27705	COG2508	Transcriptional regulator
EXW62_RS27705	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW62_RS27755	COG0083	homoserine kinase activity
EXW62_RS27775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW62_RS27785	COG2707	UPF0756 membrane protein
EXW62_RS27795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW62_RS27810	COG2002	toxin-antitoxin pair type II binding
EXW62_RS27870	COG0791	NLP P60 protein
EXW62_RS27870	COG3883	PFAM NLP P60 protein
EXW62_RS28030	COG0582	viral genome integration into host DNA