locus-tag	class	description
B7492_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B7492_RS00010	COG0592	DNA-directed DNA polymerase activity
B7492_RS00015	COG2501	S4 domain
B7492_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7492_RS00025	COG0187	DNA topoisomerase II activity
B7492_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7492_RS00065	COG0517	IMP dehydrogenase activity
B7492_RS00065	COG0516	GMP reductase activity
B7492_RS00070	COG1686	Belongs to the peptidase S11 family
B7492_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
B7492_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B7492_RS00100	COG1428	Deoxynucleoside kinase
B7492_RS00105	COG1428	Deoxynucleoside kinase
B7492_RS00110	COG1335	isochorismatase
B7492_RS00115	COG0590	tRNA wobble adenosine to inosine editing
B7492_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7492_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B7492_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7492_RS00180	COG1982	Orn Lys Arg decarboxylase major
B7492_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B7492_RS00190	COG0470	DNA polymerase III
B7492_RS00195	COG1774	PSP1 C-terminal conserved region
B7492_RS00200	COG4467	Involved in initiation control of chromosome replication
B7492_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B7492_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B7492_RS00220	COG2002	toxin-antitoxin pair type II binding
B7492_RS00230	COG0084	hydrolase, TatD family'
B7492_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7492_RS00250	COG4466	Protein conserved in bacteria
B7492_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B7492_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7492_RS00270	COG0251	oxidation-reduction process
B7492_RS00275	COG2088	sporulation resulting in formation of a cellular spore
B7492_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B7492_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7492_RS00305	COG2002	toxin-antitoxin pair type II binding
B7492_RS00310	COG2244	polysaccharide biosynthetic process
B7492_RS00315	COG3956	TIGRFAM MazG family protein
B7492_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7492_RS00340	COG1098	S1 RNA binding domain
B7492_RS00355	COG2208	phosphoserine phosphatase activity
B7492_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B7492_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7492_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B7492_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7492_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7492_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
B7492_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7492_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7492_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B7492_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7492_RS00420	COG1396	sequence-specific DNA binding
B7492_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7492_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B7492_RS00520	COG3880	PFAM UvrB UvrC protein
B7492_RS00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B7492_RS00530	COG0542	response to heat
B7492_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B7492_RS00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
B7492_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
B7492_RS00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B7492_RS00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7492_RS00565	COG1045	serine acetyltransferase
B7492_RS00570	COG0215	cysteine-tRNA ligase activity
B7492_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7492_RS00585	COG3688	RNA-binding protein containing a PIN domain
B7492_RS00595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7492_RS00600	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7492_RS00605	COG0250	Participates in transcription elongation, termination and antitermination
B7492_RS00610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B7492_RS00615	COG0081	regulation of translation
B7492_RS00620	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
B7492_RS00625	COG0222	ribosome binding
B7492_RS00630	COG2813	Specifically methylates the guanine in position
B7492_RS00635	COG0085	RNA polymerase activity
B7492_RS00640	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B7492_RS00645	COG1358	cellular component organization or biogenesis
B7492_RS00650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B7492_RS00655	COG0049	tRNA binding
B7492_RS00660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B7492_RS00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B7492_RS00670	COG0051	transcription antitermination factor activity, RNA binding
B7492_RS00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B7492_RS00680	COG0088	Forms part of the polypeptide exit tunnel
B7492_RS00685	COG0089	rRNA binding
B7492_RS00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B7492_RS00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B7492_RS00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B7492_RS00710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B7492_RS00715	COG0255	Belongs to the universal ribosomal protein uL29 family
B7492_RS00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
B7492_RS00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B7492_RS00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B7492_RS00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B7492_RS00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
B7492_RS00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B7492_RS00765	COG1841	ribosomal large subunit assembly
B7492_RS00770	COG0200	Binds to the 23S rRNA
B7492_RS00775	COG0201	protein transport
B7492_RS00780	COG0563	adenylate kinase activity
B7492_RS00785	COG0024	Methionine aminopeptidase
B7492_RS00795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B7492_RS00800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B7492_RS00805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B7492_RS00830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B7492_RS00840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B7492_RS00845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7492_RS00855	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7492_RS00860	COG0489	protein tyrosine kinase activity
B7492_RS00870	COG2194	sulfuric ester hydrolase activity
B7492_RS00875	COG0726	polysaccharide deacetylase
B7492_RS00955	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B7492_RS00960	COG4856	YbbR-like protein
B7492_RS00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7492_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS01005	COG1464	Belongs to the NlpA lipoprotein family
B7492_RS01010	COG0604	alcohol dehydrogenase
B7492_RS01020	COG0277	FAD linked oxidase domain protein
B7492_RS01025	COG2271	Major facilitator Superfamily
B7492_RS01035	COG2814	Major facilitator Superfamily
B7492_RS01055	COG0601	transmembrane transport
B7492_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7492_RS01065	COG0444	Belongs to the ABC transporter superfamily
B7492_RS01070	COG4608	Belongs to the ABC transporter superfamily
B7492_RS01075	COG4166	transmembrane transport
B7492_RS01100	COG4166	transmembrane transport
B7492_RS01105	COG4166	transmembrane transport
B7492_RS01110	COG0656	L-ascorbic acid biosynthetic process
B7492_RS01115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7492_RS01130	COG4149	molybdate abc transporter
B7492_RS01135	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7492_RS01140	COG1910	domain protein
B7492_RS01150	COG0697	spore germination
B7492_RS01165	COG0204	Acyl-transferase
B7492_RS01175	COG1609	Transcriptional regulator
B7492_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS01200	COG5298	Protein conserved in bacteria
B7492_RS01220	COG0488	(ABC) transporter
B7492_RS01230	COG0747	negative chemotaxis
B7492_RS01240	COG3335	DDE superfamily endonuclease
B7492_RS01255	COG0601	transmembrane transport
B7492_RS01260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7492_RS01265	COG0444	Belongs to the ABC transporter superfamily
B7492_RS01270	COG4608	Belongs to the ABC transporter superfamily
B7492_RS01275	COG0561	phosphatase activity
B7492_RS01305	COG3185	4-Hydroxyphenylpyruvate dioxygenase
B7492_RS01310	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7492_RS01320	COG0531	amino acid
B7492_RS01325	COG2814	Major facilitator Superfamily
B7492_RS01335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7492_RS01345	COG4294	response to UV
B7492_RS01350	COG0705	Rhomboid family
B7492_RS01355	COG0736	holo-[acyl-carrier-protein] synthase activity
B7492_RS01360	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B7492_RS01370	COG0864	Transcriptional regulator
B7492_RS01375	COG2337	Toxic component of a toxin-antitoxin (TA) module
B7492_RS01380	COG2183	response to ionizing radiation
B7492_RS01480	COG0802	atpase or kinase
B7492_RS01485	COG1214	PFAM Peptidase M22, glycoprotease
B7492_RS01490	COG0456	acetyltransferase
B7492_RS01500	COG0488	(ABC) transporter
B7492_RS01505	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B7492_RS01515	COG1266	CAAX protease self-immunity
B7492_RS01520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B7492_RS01525	COG0459	protein refolding
B7492_RS01530	COG0519	Catalyzes the synthesis of GMP from XMP
B7492_RS01530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7492_RS01535	COG2252	PERMEase
B7492_RS01545	COG5002	protein histidine kinase activity
B7492_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7492_RS01590	COG0693	protein deglycase activity
B7492_RS01650	COG2205	protein histidine kinase activity
B7492_RS01655	COG0745	RESPONSE REGULATOR receiver
B7492_RS01675	COG0697	spore germination
B7492_RS01705	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B7492_RS01710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7492_RS01715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7492_RS01720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B7492_RS01725	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7492_RS01730	COG0047	phosphoribosylformylglycinamidine synthase activity
B7492_RS01735	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7492_RS01740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B7492_RS01745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B7492_RS01750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7492_RS01755	COG0138	bifunctional purine biosynthesis protein purh
B7492_RS01760	COG0151	Belongs to the GarS family
B7492_RS01780	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B7492_RS01785	COG0210	DNA helicase
B7492_RS01790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7492_RS01795	COG4851	CamS sex pheromone cAM373 precursor
B7492_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS01810	COG1335	isochorismatase
B7492_RS01820	COG2011	ABC-type metal ion transport system permease component
B7492_RS01825	COG1464	Belongs to the NlpA lipoprotein family
B7492_RS01840	COG0003	Pfam Anion-transporting ATPase
B7492_RS01845	COG1846	Transcriptional regulator
B7492_RS01860	COG1396	sequence-specific DNA binding
B7492_RS01890	COG1484	DNA-dependent DNA replication
B7492_RS01970	COG0582	viral genome integration into host DNA
B7492_RS02030	COG4626	Terminase
B7492_RS02030	COG1802	Transcriptional regulator
B7492_RS02040	COG0740	serine-type endopeptidase activity
B7492_RS02150	COG0154	amidase activity
B7492_RS02155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7492_RS02160	COG1597	lipid kinase activity
B7492_RS02170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7492_RS02180	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS02185	COG2076	Multidrug Resistance protein
B7492_RS02190	COG2309	aminopeptidase activity
B7492_RS02205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS02215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7492_RS02220	COG5002	protein histidine kinase activity
B7492_RS02230	COG4807	Protein conserved in bacteria
B7492_RS02255	COG1757	Na H antiporter
B7492_RS02260	COG1473	amidohydrolase
B7492_RS02275	COG0450	alkyl hydroperoxide reductase
B7492_RS02285	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B7492_RS02295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS02300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS02305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS02315	COG0492	ferredoxin-NADP+ reductase activity
B7492_RS02325	COG0166	Belongs to the GPI family
B7492_RS02350	COG5002	protein histidine kinase activity
B7492_RS02370	COG3541	Predicted nucleotidyltransferase
B7492_RS02380	COG2814	Major facilitator Superfamily
B7492_RS02385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7492_RS02385	COG0723	plastoquinol--plastocyanin reductase activity
B7492_RS02395	COG0765	amino acid transport
B7492_RS02400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7492_RS02410	COG0840	transmembrane signaling receptor activity
B7492_RS02410	COG3290	protein histidine kinase activity
B7492_RS02415	COG0277	FAD linked oxidase domain protein
B7492_RS02420	COG0366	Alpha amylase catalytic
B7492_RS02425	COG2190	(PTS) system
B7492_RS02425	COG1263	PTS System
B7492_RS02425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7492_RS02445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B7492_RS02450	COG0352	thiamine-phosphate diphosphorylase activity
B7492_RS02455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B7492_RS02475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7492_RS02480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7492_RS02485	COG1116	anion transmembrane transporter activity
B7492_RS02490	COG0488	(ABC) transporter
B7492_RS02530	COG2270	Major facilitator Superfamily
B7492_RS02560	COG2310	stress, protein
B7492_RS02565	COG2310	stress, protein
B7492_RS02570	COG2310	stress, protein
B7492_RS02575	COG0861	Integral membrane protein TerC family
B7492_RS02585	COG3853	Toxic anion resistance protein (TelA)
B7492_RS02595	COG4840	Belongs to the UPF0435 family
B7492_RS02600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7492_RS02610	COG1295	ribonuclease BN
B7492_RS02615	COG2217	Heavy metal translocating P-type atpase
B7492_RS02620	COG0697	spore germination
B7492_RS02640	COG0586	Pfam SNARE associated Golgi protein
B7492_RS02655	COG3871	stress protein (general stress protein 26)
B7492_RS02660	COG0387	Pfam Sodium calcium exchanger
B7492_RS02670	COG0535	radical SAM domain protein
B7492_RS02690	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B7492_RS02710	COG3829	transcription factor binding
B7492_RS02720	COG0833	amino acid
B7492_RS02725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7492_RS02745	COG2066	Belongs to the glutaminase family
B7492_RS02755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7492_RS02755	COG1263	PTS System
B7492_RS02760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS02780	COG1216	Glycosyl transferase, family 2
B7492_RS02790	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7492_RS02790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7492_RS02810	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B7492_RS02815	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B7492_RS02830	COG1228	amidohydrolase
B7492_RS02835	COG1090	epimerase
B7492_RS02840	COG2137	regulation of response to DNA damage stimulus
B7492_RS02865	COG1988	membrane-bound metal-dependent
B7492_RS02870	COG1194	a g-specific adenine glycosylase
B7492_RS02890	COG3557	Belongs to the UPF0374 family
B7492_RS02895	COG1132	(ABC) transporter
B7492_RS02900	COG4129	membrane
B7492_RS02905	COG0069	glutamate synthase activity
B7492_RS02905	COG0070	glutamate synthase
B7492_RS02905	COG0067	glutamate synthase
B7492_RS02910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7492_RS02915	COG4555	ABC transporter
B7492_RS02935	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7492_RS02940	COG0735	belongs to the Fur family
B7492_RS03060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
B7492_RS03065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7492_RS03085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7492_RS03095	COG2766	serine protein kinase
B7492_RS03100	COG2718	Belongs to the UPF0229 family
B7492_RS03115	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7492_RS03120	COG2268	Band 7 protein
B7492_RS03130	COG3290	protein histidine kinase activity
B7492_RS03135	COG4565	transcriptional regulatory protein
B7492_RS03140	COG2851	Citrate transporter
B7492_RS03170	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B7492_RS03175	COG3842	ATPase activity
B7492_RS03180	COG1175	transmembrane transport
B7492_RS03185	COG0395	ABC-type sugar transport system, permease component
B7492_RS03195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7492_RS03200	COG0745	RESPONSE REGULATOR receiver
B7492_RS03205	COG5002	protein histidine kinase activity
B7492_RS03215	COG4990	cell redox homeostasis
B7492_RS03225	COG3290	protein histidine kinase activity
B7492_RS03230	COG4565	transcriptional regulatory protein
B7492_RS03235	COG3493	citrate carrier protein
B7492_RS03240	COG0281	malic enzyme
B7492_RS03250	COG0697	spore germination
B7492_RS03255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS03270	COG5002	protein histidine kinase activity
B7492_RS03275	COG0745	RESPONSE REGULATOR receiver
B7492_RS03280	COG0456	acetyltransferase
B7492_RS03285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7492_RS03290	COG3383	formate dehydrogenase (NAD+) activity
B7492_RS03295	COG2427	Protein of unknown function (DUF1641)
B7492_RS03310	COG0531	amino acid
B7492_RS03320	COG0640	Transcriptional regulator
B7492_RS03325	COG2217	Heavy metal translocating P-type atpase
B7492_RS03330	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B7492_RS03340	COG3227	Zinc metalloprotease (Elastase)
B7492_RS03360	COG2720	vancomycin resistance protein
B7492_RS03365	COG1316	TRANSCRIPTIONal
B7492_RS03370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS03375	COG0346	lactoylglutathione lyase activity
B7492_RS03380	COG1253	flavin adenine dinucleotide binding
B7492_RS03385	COG1027	Aspartate ammonia-lyase
B7492_RS03390	COG1620	l-lactate permease
B7492_RS03395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS03415	COG3104	oligopeptide transport
B7492_RS03420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS03425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS03430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS03445	COG0156	8-amino-7-oxononanoate synthase activity
B7492_RS03450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7492_RS03460	COG4548	von Willebrand factor, type A
B7492_RS03465	COG0714	Associated with various cellular activities
B7492_RS03485	COG0531	amino acid
B7492_RS03490	COG2188	Transcriptional regulator
B7492_RS03495	COG1263	PTS System
B7492_RS03495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7492_RS03500	COG0366	Alpha amylase catalytic
B7492_RS03515	COG0697	spore germination
B7492_RS03520	COG4585	Histidine kinase
B7492_RS03525	COG2197	response regulator
B7492_RS03530	COG1404	Belongs to the peptidase S8 family
B7492_RS03545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7492_RS03550	COG1115	amino acid carrier protein
B7492_RS03555	COG1126	abc transporter atp-binding protein
B7492_RS03560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7492_RS03565	COG0765	amino acid transport
B7492_RS03570	COG0765	amino acid transport
B7492_RS03575	COG0833	amino acid
B7492_RS03605	COG2378	regulation of single-species biofilm formation
B7492_RS03610	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7492_RS03615	COG5002	protein histidine kinase activity
B7492_RS03645	COG2271	Major facilitator Superfamily
B7492_RS03650	COG1846	Transcriptional regulator
B7492_RS03655	COG0477	Major facilitator Superfamily
B7492_RS03660	COG1609	Transcriptional regulator
B7492_RS03665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7492_RS03670	COG1869	D-ribose catabolic process
B7492_RS03680	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7492_RS03685	COG1879	ABC-type sugar transport system periplasmic component
B7492_RS03715	COG1063	alcohol dehydrogenase
B7492_RS03730	COG3568	Endonuclease Exonuclease Phosphatase
B7492_RS03760	COG0840	transmembrane signaling receptor activity
B7492_RS03765	COG3584	3D domain protein
B7492_RS03765	COG3583	domain protein
B7492_RS03770	COG1476	TRANSCRIPTIONal
B7492_RS03790	COG3104	oligopeptide transport
B7492_RS03795	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS03810	COG1113	amino acid transport
B7492_RS03815	COG2252	PERMEase
B7492_RS03835	COG2153	protein acetylation
B7492_RS03850	COG0569	domain protein
B7492_RS03850	COG0475	glutathione-regulated potassium exporter activity
B7492_RS03865	COG1845	cytochrome c oxidase, subunit III
B7492_RS03870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7492_RS03880	COG0833	amino acid
B7492_RS03885	COG4990	cell redox homeostasis
B7492_RS03900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7492_RS03905	COG0697	spore germination
B7492_RS03910	COG0531	amino acid
B7492_RS03920	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B7492_RS03925	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B7492_RS03935	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7492_RS03940	COG0573	inorganic phosphate transmembrane transporter activity
B7492_RS03945	COG0581	inorganic phosphate transmembrane transporter activity
B7492_RS03955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7492_RS04075	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B7492_RS04095	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7492_RS04095	COG3103	Sh3 type 3 domain protein
B7492_RS04095	COG4991	sh3 domain protein
B7492_RS04100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7492_RS04105	COG1116	anion transmembrane transporter activity
B7492_RS04110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7492_RS04115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7492_RS04120	COG0352	thiamine-phosphate diphosphorylase activity
B7492_RS04125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7492_RS04130	COG2104	thiamine diphosphate biosynthetic process
B7492_RS04135	COG2022	thiamine diphosphate biosynthetic process
B7492_RS04140	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7492_RS04145	COG0351	phosphomethylpyrimidine kinase
B7492_RS04165	COG1136	(ABC) transporter
B7492_RS04195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B7492_RS04200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7492_RS04205	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
B7492_RS04210	COG2205	protein histidine kinase activity
B7492_RS04215	COG2814	Major facilitator Superfamily
B7492_RS04220	COG1846	Transcriptional regulator
B7492_RS04235	COG1396	sequence-specific DNA binding
B7492_RS04265	COG1846	Transcriptional regulator
B7492_RS04270	COG1484	DNA-dependent DNA replication
B7492_RS04295	COG3335	DDE superfamily endonuclease
B7492_RS04350	COG0582	viral genome integration into host DNA
B7492_RS04390	COG1802	Transcriptional regulator
B7492_RS04390	COG4626	Terminase
B7492_RS04400	COG0740	serine-type endopeptidase activity
B7492_RS04410	COG4733	cellulase activity
B7492_RS04410	COG5297	Belongs to the glycosyl hydrolase family 6
B7492_RS04475	COG4824	toxin secretion phage lysis holin
B7492_RS04480	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7492_RS04480	COG3409	Peptidoglycan-binding domain 1 protein
B7492_RS04480	COG1388	LysM domain
B7492_RS04510	COG2252	PERMEase
B7492_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS04580	COG0778	Nitroreductase
B7492_RS04585	COG2719	SpoVR family
B7492_RS04605	COG1937	Protein conserved in bacteria
B7492_RS04610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS04610	COG0425	Belongs to the sulfur carrier protein TusA family
B7492_RS04615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS04615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS04620	COG0425	Belongs to the sulfur carrier protein TusA family
B7492_RS04625	COG0425	Belongs to the sulfur carrier protein TusA family
B7492_RS04625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS04630	COG2210	Belongs to the sulfur carrier protein TusA family
B7492_RS04635	COG0730	response to heat
B7492_RS04645	COG1316	TRANSCRIPTIONal
B7492_RS04650	COG0604	alcohol dehydrogenase
B7492_RS04655	COG1283	sodium-dependent phosphate transmembrane transporter activity
B7492_RS04660	COG2814	Major facilitator Superfamily
B7492_RS04675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7492_RS04675	COG3711	transcriptional antiterminator
B7492_RS04680	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7492_RS04685	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7492_RS04705	COG1388	LysM domain
B7492_RS04705	COG3584	3D domain protein
B7492_RS04710	COG0577	efflux transmembrane transporter activity
B7492_RS04715	COG1136	(ABC) transporter
B7492_RS04725	COG0577	efflux transmembrane transporter activity
B7492_RS04730	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS04735	COG3546	catalase activity
B7492_RS04760	COG0586	Pfam SNARE associated Golgi protein
B7492_RS04790	COG0531	amino acid
B7492_RS04795	COG0475	glutathione-regulated potassium exporter activity
B7492_RS04805	COG1737	Transcriptional regulator
B7492_RS04815	COG1263	PTS System
B7492_RS04815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7492_RS04825	COG2259	Doxx family
B7492_RS04845	COG0697	spore germination
B7492_RS04850	COG1522	sequence-specific DNA binding
B7492_RS04860	COG0300	oxidoreductase activity
B7492_RS04875	COG2076	Multidrug Resistance protein
B7492_RS04880	COG1309	transcriptional regulator
B7492_RS04885	COG2814	Major facilitator Superfamily
B7492_RS04915	COG0531	amino acid
B7492_RS04920	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS04940	COG1132	(ABC) transporter
B7492_RS04945	COG1132	(ABC) transporter
B7492_RS04950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7492_RS04955	COG0765	amino acid transport
B7492_RS04960	COG1126	abc transporter atp-binding protein
B7492_RS04975	COG0189	ligase activity
B7492_RS04985	COG4399	Belongs to the UPF0754 family
B7492_RS04990	COG3679	Belongs to the UPF0342 family
B7492_RS05005	COG0028	Belongs to the TPP enzyme family
B7492_RS05010	COG3527	Alpha-acetolactate decarboxylase
B7492_RS05015	COG0463	Glycosyl transferase, family 2
B7492_RS05020	COG1216	Glycosyl transferase, family 2
B7492_RS05025	COG2094	Belongs to the DNA glycosylase MPG family
B7492_RS05030	COG0561	phosphatase activity
B7492_RS05040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7492_RS05050	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS05060	COG0659	secondary active sulfate transmembrane transporter activity
B7492_RS05075	COG0653	protein targeting
B7492_RS05080	COG2244	polysaccharide biosynthetic process
B7492_RS05115	COG1696	Membrane protein involved in D-alanine export
B7492_RS05130	COG1024	Enoyl-CoA hydratase
B7492_RS05145	COG1363	Peptidase, m42
B7492_RS05175	COG0579	oxidoreductase
B7492_RS05200	COG0601	transmembrane transport
B7492_RS05205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7492_RS05210	COG0444	Belongs to the ABC transporter superfamily
B7492_RS05215	COG4608	Belongs to the ABC transporter superfamily
B7492_RS05220	COG0322	excinuclease ABC activity
B7492_RS05270	COG0582	viral genome integration into host DNA
B7492_RS05350	COG0477	Major facilitator Superfamily
B7492_RS05355	COG3290	protein histidine kinase activity
B7492_RS05360	COG4565	transcriptional regulatory protein
B7492_RS05365	COG3181	Tripartite tricarboxylate transporter family receptor
B7492_RS05370	COG0494	nUDIX hydrolase
B7492_RS05400	COG0305	Participates in initiation and elongation during chromosome replication
B7492_RS05500	COG2814	Major facilitator Superfamily
B7492_RS05505	COG0640	Transcriptional regulator
B7492_RS05530	COG2376	Dihydroxyacetone kinase
B7492_RS05540	COG2376	Dihydroxyacetone kinase
B7492_RS05555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7492_RS05585	COG0662	Cupin 2, conserved barrel domain protein
B7492_RS05600	COG2140	Oxalate decarboxylase
B7492_RS05625	COG3237	CsbD-like
B7492_RS05645	COG2172	sigma factor antagonist activity
B7492_RS05650	COG1191	sigma factor activity
B7492_RS05660	COG2208	phosphoserine phosphatase activity
B7492_RS05665	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7492_RS05670	COG0784	Response regulator, receiver
B7492_RS05670	COG2205	protein histidine kinase activity
B7492_RS05670	COG5002	protein histidine kinase activity
B7492_RS05705	COG4585	Histidine kinase
B7492_RS05710	COG2197	response regulator
B7492_RS05740	COG0420	3'-5' exonuclease activity
B7492_RS05745	COG4717	serine-type aminopeptidase activity
B7492_RS05750	COG3481	metal-dependent phosphohydrolase, HD sub domain
B7492_RS05755	COG0346	lactoylglutathione lyase activity
B7492_RS05765	COG3344	reverse transcriptase
B7492_RS05770	COG0457	Tetratricopeptide repeat
B7492_RS05785	COG2267	carboxylic ester hydrolase activity
B7492_RS05795	COG3620	sequence-specific DNA binding
B7492_RS05800	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B7492_RS05805	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B7492_RS05810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7492_RS05815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B7492_RS05830	COG1595	DNA-templated transcription, initiation
B7492_RS05845	COG3973	AAA domain
B7492_RS05850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7492_RS05875	COG0537	adenosine 5'-monophosphoramidase activity
B7492_RS05880	COG1131	(ABC) transporter
B7492_RS05885	COG4473	ABC transporter
B7492_RS05895	COG0247	lactate metabolic process
B7492_RS05900	COG1139	Iron-sulfur cluster binding protein
B7492_RS05905	COG1556	Lactate utilization protein
B7492_RS05920	COG3402	PFAM membrane-flanked domain
B7492_RS05925	COG3428	Bacterial PH domain
B7492_RS05970	COG3402	PFAM membrane-flanked domain
B7492_RS05975	COG3428	Bacterial PH domain
B7492_RS05980	COG2329	Antibiotic biosynthesis monooxygenase
B7492_RS05985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7492_RS05990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
B7492_RS05995	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B7492_RS06000	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7492_RS06025	COG1309	transcriptional regulator
B7492_RS06030	COG1511	domain protein
B7492_RS06065	COG1609	Transcriptional regulator
B7492_RS06075	COG1234	tRNA 3'-trailer cleavage
B7492_RS06080	COG0095	Lipoate-protein ligase
B7492_RS06090	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS06105	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7492_RS06110	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7492_RS06115	COG4208	sulfate ABC transporter
B7492_RS06135	COG1309	transcriptional regulator
B7492_RS06140	COG1073	alpha beta
B7492_RS06145	COG1408	metallophosphoesterase
B7492_RS06150	COG1078	dGTPase activity
B7492_RS06160	COG1595	DNA-templated transcription, initiation
B7492_RS06170	COG3708	Transcriptional regulator
B7492_RS06170	COG2207	Transcriptional regulator
B7492_RS06175	COG2205	protein histidine kinase activity
B7492_RS06180	COG0745	RESPONSE REGULATOR receiver
B7492_RS06200	COG0501	Belongs to the peptidase M48B family
B7492_RS06205	COG0840	transmembrane signaling receptor activity
B7492_RS06210	COG0697	spore germination
B7492_RS06235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7492_RS06240	COG2224	Isocitrate lyase
B7492_RS06250	COG1278	Cold shock
B7492_RS06265	COG4903	ComK protein
B7492_RS06275	COG0398	Pfam SNARE associated Golgi protein
B7492_RS06285	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B7492_RS06290	COG1074	ATP-dependent DNA helicase activity
B7492_RS06340	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7492_RS06365	COG0367	asparagine synthase
B7492_RS06380	COG0753	catalase activity
B7492_RS06385	COG0004	ammonium transporteR
B7492_RS06395	COG1666	GTP binding
B7492_RS06400	COG2996	Protein conserved in bacteria
B7492_RS06415	COG1329	Transcriptional regulator
B7492_RS06440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7492_RS06450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS06465	COG0561	phosphatase activity
B7492_RS06485	COG2267	carboxylic ester hydrolase activity
B7492_RS06500	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7492_RS06505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7492_RS06510	COG5504	Zn-dependent protease
B7492_RS06530	COG0180	Tryptophanyl-tRNA synthetase
B7492_RS06545	COG4166	transmembrane transport
B7492_RS06550	COG0601	transmembrane transport
B7492_RS06555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7492_RS06560	COG0444	Belongs to the ABC transporter superfamily
B7492_RS06565	COG4608	Belongs to the ABC transporter superfamily
B7492_RS06570	COG0534	Mate efflux family protein
B7492_RS06575	COG4166	transmembrane transport
B7492_RS06595	COG0861	Integral membrane protein TerC family
B7492_RS06600	COG4862	establishment of competence for transformation
B7492_RS06605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7492_RS06615	COG1164	Oligoendopeptidase f
B7492_RS06625	COG2346	COG2346, Truncated hemoglobins
B7492_RS06630	COG4116	CYTH
B7492_RS06640	COG2357	RelA SpoT domain protein
B7492_RS06650	COG0564	pseudouridine synthase activity
B7492_RS06660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7492_RS06665	COG0772	Belongs to the SEDS family
B7492_RS06670	COG1216	Glycosyl transferase, family 2
B7492_RS06690	COG0457	Tetratricopeptide repeat
B7492_RS06690	COG0463	Glycosyl transferase, family 2
B7492_RS06710	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B7492_RS06725	COG1091	dTDP-4-dehydrorhamnose reductase activity
B7492_RS06770	COG2153	protein acetylation
B7492_RS06775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B7492_RS06780	COG2382	esterase
B7492_RS06805	COG5492	domain, Protein
B7492_RS06810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7492_RS06825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7492_RS06825	COG0512	Glutamine amidotransferase of anthranilate synthase
B7492_RS06830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7492_RS06835	COG0134	indole-3-glycerol-phosphate synthase activity
B7492_RS06840	COG0135	phosphoribosylanthranilate isomerase activity
B7492_RS06845	COG0133	tryptophan synthase activity
B7492_RS06850	COG0159	tryptophan synthase activity
B7492_RS06860	COG1620	l-lactate permease
B7492_RS06865	COG5634	Uncharacterized conserved protein (DUF2278)
B7492_RS06935	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7492_RS06940	COG0567	Dehydrogenase, E1 component
B7492_RS06970	COG4152	abc transporter atp-binding protein
B7492_RS06975	COG1668	transmembrane transport
B7492_RS07050	COG0582	viral genome integration into host DNA
B7492_RS07070	COG1686	Belongs to the peptidase S11 family
B7492_RS07075	COG0681	Belongs to the peptidase S26 family
B7492_RS07110	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS07120	COG1176	ABC-type spermidine putrescine transport system, permease component I
B7492_RS07125	COG1177	transmembrane transport
B7492_RS07130	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
B7492_RS07140	COG2409	Drug exporters of the RND superfamily
B7492_RS07155	COG0564	pseudouridine synthase activity
B7492_RS07165	COG2340	Cysteine-rich secretory protein family
B7492_RS07170	COG0247	lactate metabolic process
B7492_RS07175	COG0277	FAD linked oxidase domain protein
B7492_RS07180	COG3835	regulator
B7492_RS07190	COG0745	RESPONSE REGULATOR receiver
B7492_RS07195	COG5002	protein histidine kinase activity
B7492_RS07200	COG2186	Transcriptional regulator
B7492_RS07205	COG0247	lactate metabolic process
B7492_RS07210	COG1139	Iron-sulfur cluster binding protein
B7492_RS07215	COG1556	Lactate utilization protein
B7492_RS07220	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B7492_RS07230	COG2116	formate transmembrane transporter activity
B7492_RS07235	COG0861	Integral membrane protein TerC family
B7492_RS07240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7492_RS07250	COG2030	dehydratase
B7492_RS07270	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS07275	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7492_RS07285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7492_RS07300	COG1840	ABC-type Fe3 transport system, periplasmic component
B7492_RS07305	COG3842	ATPase activity
B7492_RS07315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7492_RS07320	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7492_RS07340	COG0235	Class ii aldolase
B7492_RS07350	COG2861	carbohydrate metabolic process
B7492_RS07360	COG3852	Histidine kinase
B7492_RS07365	COG1846	Transcriptional regulator
B7492_RS07375	COG2318	DinB family
B7492_RS07380	COG5002	protein histidine kinase activity
B7492_RS07385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B7492_RS07390	COG0720	synthase
B7492_RS07400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B7492_RS07405	COG4873	Protein conserved in bacteria
B7492_RS07415	COG0456	acetyltransferase
B7492_RS07435	COG1780	Probably involved in ribonucleotide reductase function
B7492_RS07440	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7492_RS07445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7492_RS07450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7492_RS07455	COG0531	amino acid
B7492_RS07465	COG3290	protein histidine kinase activity
B7492_RS07465	COG3829	transcription factor binding
B7492_RS07470	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS07480	COG1725	Transcriptional regulator
B7492_RS07485	COG1131	(ABC) transporter
B7492_RS07495	COG1131	(ABC) transporter
B7492_RS07500	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7492_RS07505	COG1266	CAAX protease self-immunity
B7492_RS07515	COG1522	sequence-specific DNA binding
B7492_RS07525	COG1335	isochorismatase
B7492_RS07535	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7492_RS07540	COG2070	2-Nitropropane dioxygenase
B7492_RS07545	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B7492_RS07550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7492_RS07555	COG1696	Membrane protein involved in D-alanine export
B7492_RS07560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7492_RS07575	COG0716	FMN binding
B7492_RS07605	COG1968	undecaprenyl-diphosphatase activity
B7492_RS07625	COG1846	Transcriptional regulator
B7492_RS07635	COG1301	dicarboxylic acid transport
B7492_RS07640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7492_RS07650	COG3874	Sporulation protein YtfJ
B7492_RS07670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7492_RS07675	COG0028	Belongs to the TPP enzyme family
B7492_RS07680	COG0440	acetolactate synthase activity
B7492_RS07690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7492_RS07700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B7492_RS07710	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B7492_RS07715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7492_RS07725	COG0131	Imidazoleglycerol-phosphate dehydratase
B7492_RS07730	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7492_RS07735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B7492_RS07740	COG0107	imidazoleglycerol-phosphate synthase activity
B7492_RS07750	COG0140	phosphoribosyl-ATP diphosphatase activity
B7492_RS07755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7492_RS07770	COG1183	phosphatidylcholine synthase activity
B7492_RS07775	COG1368	sulfuric ester hydrolase activity
B7492_RS07780	COG0582	viral genome integration into host DNA
B7492_RS07825	COG1484	DNA-dependent DNA replication
B7492_RS07835	COG2002	toxin-antitoxin pair type II binding
B7492_RS07910	COG4824	toxin secretion phage lysis holin
B7492_RS07925	COG0019	diaminopimelate decarboxylase activity
B7492_RS07935	COG0175	sulfate reduction
B7492_RS07940	COG2046	Belongs to the sulfate adenylyltransferase family
B7492_RS07945	COG0529	Catalyzes the synthesis of activated sulfate
B7492_RS07950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7492_RS07970	COG1648	precorrin-2 dehydrogenase activity
B7492_RS07975	COG0733	neurotransmitter:sodium symporter activity
B7492_RS07995	COG1757	Na H antiporter
B7492_RS08015	COG4758	membrane
B7492_RS08020	COG4585	Histidine kinase
B7492_RS08025	COG2197	response regulator
B7492_RS08035	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS08045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7492_RS08085	COG0730	response to heat
B7492_RS08090	COG0306	phosphate transporter
B7492_RS08095	COG1392	Phosphate transport regulator
B7492_RS08110	COG3852	Histidine kinase
B7492_RS08115	COG1801	Protein of unknown function DUF72
B7492_RS08130	COG0582	viral genome integration into host DNA
B7492_RS08135	COG5002	protein histidine kinase activity
B7492_RS08150	COG0392	lysyltransferase activity
B7492_RS08150	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B7492_RS08165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7492_RS08170	COG1686	Belongs to the peptidase S11 family
B7492_RS08175	COG2715	membrane protein required for spore maturation
B7492_RS08180	COG0700	Nucleoside recognition
B7492_RS08185	COG1187	pseudouridine synthase activity
B7492_RS08195	COG1333	cytochrome c biogenesis protein
B7492_RS08200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7492_RS08205	COG0745	RESPONSE REGULATOR receiver
B7492_RS08210	COG5002	protein histidine kinase activity
B7492_RS08215	COG2096	Adenosyltransferase
B7492_RS08220	COG4942	peptidase
B7492_RS08230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B7492_RS08235	COG1141	Ferredoxin
B7492_RS08245	COG4955	Helix-turn-helix domain
B7492_RS08250	COG0514	ATP-dependent DNA helicase (RecQ)
B7492_RS08255	COG1266	CAAX protease self-immunity
B7492_RS08265	COG1408	metallophosphoesterase
B7492_RS08280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7492_RS08300	COG0492	ferredoxin-NADP+ reductase activity
B7492_RS08305	COG0252	asparaginase activity
B7492_RS08310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7492_RS08320	COG1304	FMN binding
B7492_RS08355	COG1160	GTP binding
B7492_RS08360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
B7492_RS08380	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7492_RS08390	COG0302	gtp cyclohydrolase
B7492_RS08400	COG0142	geranyltranstransferase activity
B7492_RS08405	COG2226	methyltransferase
B7492_RS08410	COG0142	geranyltranstransferase activity
B7492_RS08425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B7492_RS08435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7492_RS08440	COG0457	Tetratricopeptide repeat
B7492_RS08445	COG5582	Belongs to the UPF0302 family
B7492_RS08460	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B7492_RS08475	COG4347	Protein of unknown function (DUF1405)
B7492_RS08490	COG2738	Putative neutral zinc metallopeptidase
B7492_RS08500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS08505	COG1694	Mazg nucleotide pyrophosphohydrolase
B7492_RS08510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B7492_RS08515	COG1803	Methylglyoxal synthase
B7492_RS08520	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7492_RS08525	COG0438	transferase activity, transferring glycosyl groups
B7492_RS08530	COG0617	tRNA 3'-terminal CCA addition
B7492_RS08540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
B7492_RS08545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B7492_RS08555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7492_RS08555	COG1199	ATP-dependent helicase activity
B7492_RS08575	COG3935	DnaD domain protein
B7492_RS08580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7492_RS08590	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7492_RS08590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7492_RS08595	COG3331	DNA recombination
B7492_RS08630	COG4474	Belongs to the UPF0398 family
B7492_RS08635	COG3599	regulation of cell shape
B7492_RS08645	COG0116	Belongs to the methyltransferase superfamily
B7492_RS08655	COG1199	ATP-dependent helicase activity
B7492_RS08660	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B7492_RS08670	COG3173	Aminoglycoside phosphotransferase
B7492_RS08675	COG0024	Methionine aminopeptidase
B7492_RS08685	COG2233	PERMEase
B7492_RS08690	COG2311	Membrane
B7492_RS08695	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7492_RS08705	COG0456	acetyltransferase
B7492_RS08715	COG2897	thiosulfate sulfurtransferase activity
B7492_RS08755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7492_RS08770	COG0454	-acetyltransferase
B7492_RS08790	COG0328	RNA-DNA hybrid ribonuclease activity
B7492_RS08830	COG3403	YqcI/YcgG family
B7492_RS08835	COG1280	lysine exporter protein (LysE YggA)
B7492_RS08850	COG3162	membrane
B7492_RS08855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7492_RS08860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7492_RS08870	COG0475	glutathione-regulated potassium exporter activity
B7492_RS08875	COG0789	Transcriptional regulator
B7492_RS08875	COG4978	Transcriptional regulator
B7492_RS08885	COG2323	membrane
B7492_RS08890	COG1434	Gram-negative-bacterium-type cell wall biogenesis
B7492_RS08930	COG2814	Major facilitator Superfamily
B7492_RS08950	COG1923	regulation of RNA biosynthetic process
B7492_RS08960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7492_RS08965	COG1360	Flagellar Motor Protein
B7492_RS08970	COG2201	protein-glutamate methylesterase activity
B7492_RS08975	COG2198	Histidine kinase
B7492_RS08975	COG0643	Histidine kinase
B7492_RS08980	COG1776	CheC inhibitor of MCP methylation
B7492_RS08980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7492_RS08995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B7492_RS09015	COG1256	bacterial-type flagellum assembly
B7492_RS09020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7492_RS09045	COG1815	bacterial-type flagellum-dependent cell motility
B7492_RS09050	COG1558	bacterial-type flagellum-dependent cell motility
B7492_RS09060	COG1766	The M ring may be actively involved in energy transduction
B7492_RS09065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7492_RS09075	COG1157	protein secretion by the type III secretion system
B7492_RS09095	COG1749	Flagellar hook protein flgE
B7492_RS09110	COG0835	chemotaxis
B7492_RS09110	COG0784	Response regulator, receiver
B7492_RS09120	COG0697	spore germination
B7492_RS09135	COG0861	Integral membrane protein TerC family
B7492_RS09145	COG3383	formate dehydrogenase (NAD+) activity
B7492_RS09150	COG2427	Protein of unknown function (DUF1641)
B7492_RS09155	COG5609	conserved protein (DUF2294)
B7492_RS09160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7492_RS09170	COG2116	formate transmembrane transporter activity
B7492_RS09175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7492_RS09180	COG0303	'Molybdopterin
B7492_RS09185	COG0314	molybdopterin synthase activity
B7492_RS09190	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
B7492_RS09200	COG0489	protein tyrosine kinase activity
B7492_RS09205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7492_RS09210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B7492_RS09215	COG0741	lytic transglycosylase activity
B7492_RS09225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7492_RS09230	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B7492_RS09230	COG1776	CheC inhibitor of MCP methylation
B7492_RS09240	COG1338	Plays a role in the flagellum-specific transport system
B7492_RS09245	COG1987	bacterial-type flagellum assembly
B7492_RS09255	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7492_RS09260	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B7492_RS09265	COG1419	protein localization to endoplasmic reticulum
B7492_RS09270	COG4787	bacterial-type flagellum-dependent cell motility
B7492_RS09315	COG2329	Antibiotic biosynthesis monooxygenase
B7492_RS09330	COG2814	Major facilitator Superfamily
B7492_RS09340	COG0583	DNA-binding transcription factor activity
B7492_RS09390	COG1686	Belongs to the peptidase S11 family
B7492_RS09425	COG0367	asparagine synthase
B7492_RS09455	COG1802	Transcriptional regulator
B7492_RS09460	COG0697	spore germination
B7492_RS09470	COG0523	cobalamin synthesis protein
B7492_RS09475	COG0438	transferase activity, transferring glycosyl groups
B7492_RS09475	COG1216	Glycosyl transferase, family 2
B7492_RS09480	COG1757	Na H antiporter
B7492_RS09505	COG0534	Mate efflux family protein
B7492_RS09510	COG3340	Belongs to the peptidase S51 family
B7492_RS09530	COG0785	Cytochrome C biogenesis protein
B7492_RS09535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS09550	COG3048	D-serine ammonia-lyase activity
B7492_RS09555	COG2733	membrane
B7492_RS09595	COG1131	(ABC) transporter
B7492_RS09610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7492_RS09615	COG0528	UMP kinase activity
B7492_RS09625	COG1027	Aspartate ammonia-lyase
B7492_RS09630	COG0281	malic enzyme
B7492_RS09635	COG4191	Histidine kinase
B7492_RS09640	COG0784	Response regulator, receiver
B7492_RS09645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7492_RS09660	COG2502	aspartate--ammonia ligase
B7492_RS09700	COG2816	NAD+ diphosphatase activity
B7492_RS09715	COG2814	Major facilitator Superfamily
B7492_RS09740	COG1695	Transcriptional regulator
B7492_RS09750	COG0477	Major facilitator Superfamily
B7492_RS09755	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7492_RS09765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7492_RS09770	COG2223	nitrite transmembrane transporter activity
B7492_RS09775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7492_RS09790	COG2244	polysaccharide biosynthetic process
B7492_RS09795	COG0733	neurotransmitter:sodium symporter activity
B7492_RS09805	COG5566	PFAM Mor transcription activator
B7492_RS09810	COG2323	membrane
B7492_RS09825	COG1733	regulation of RNA biosynthetic process
B7492_RS09830	COG0110	maltose O-acetyltransferase activity
B7492_RS09835	COG1733	regulation of RNA biosynthetic process
B7492_RS09840	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7492_RS09845	COG1982	Orn Lys Arg decarboxylase major
B7492_RS09855	COG0833	amino acid
B7492_RS09860	COG0450	alkyl hydroperoxide reductase
B7492_RS09865	COG3634	alkyl hydroperoxide reductase activity
B7492_RS09870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7492_RS09880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7492_RS09885	COG0028	Belongs to the TPP enzyme family
B7492_RS09905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7492_RS09930	COG2814	Major facilitator Superfamily
B7492_RS09935	COG3384	dioxygenase
B7492_RS09980	COG4166	transmembrane transport
B7492_RS09985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS10005	COG1914	H( )-stimulated, divalent metal cation uptake system
B7492_RS10010	COG1054	Belongs to the UPF0176 family
B7492_RS10020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7492_RS10025	COG0531	amino acid
B7492_RS10060	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7492_RS10075	COG4257	antibiotic catabolic process
B7492_RS10080	COG2390	Transcriptional regulator
B7492_RS10090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B7492_RS10095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS10100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
B7492_RS10115	COG4846	Membrane protein involved in cytochrome C biogenesis
B7492_RS10130	COG0583	DNA-binding transcription factor activity
B7492_RS10150	COG2801	Transposase and inactivated derivatives
B7492_RS10160	COG2132	Multicopper oxidase
B7492_RS10170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7492_RS10190	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS10200	COG4641	Protein conserved in bacteria
B7492_RS10210	COG1276	copper resistance
B7492_RS10210	COG2372	response to copper ion
B7492_RS10215	COG4549	nuclear export factor GLE1
B7492_RS10225	COG0697	spore germination
B7492_RS10230	COG0583	DNA-binding transcription factor activity
B7492_RS10235	COG1959	2 iron, 2 sulfur cluster binding
B7492_RS10240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7492_RS10245	COG0778	Nitroreductase
B7492_RS10255	COG0628	permease
B7492_RS10270	COG1231	oxidoreductase activity
B7492_RS10275	COG0523	cobalamin synthesis protein
B7492_RS10285	COG0411	ABC transporter
B7492_RS10305	COG0583	DNA-binding transcription factor activity
B7492_RS10315	COG1942	4-Oxalocrotonate Tautomerase
B7492_RS10330	COG0346	lactoylglutathione lyase activity
B7492_RS10340	COG1271	oxidase subunit
B7492_RS10345	COG1294	oxidase, subunit
B7492_RS10350	COG4988	ABC transporter
B7492_RS10355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
B7492_RS10385	COG1686	Belongs to the peptidase S11 family
B7492_RS10395	COG0791	NLP P60 protein
B7492_RS10395	COG1388	LysM domain
B7492_RS10405	COG1132	(ABC) transporter
B7492_RS10410	COG0745	RESPONSE REGULATOR receiver
B7492_RS10415	COG5002	protein histidine kinase activity
B7492_RS10420	COG0300	oxidoreductase activity
B7492_RS10425	COG4122	O-methyltransferase activity
B7492_RS10455	COG0460	homoserine dehydrogenase
B7492_RS10465	COG0083	homoserine kinase activity
B7492_RS10480	COG1316	TRANSCRIPTIONal
B7492_RS10495	COG1285	pathogenesis
B7492_RS10500	COG1247	-acetyltransferase
B7492_RS10520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7492_RS10530	COG1082	Xylose isomerase domain protein TIM barrel
B7492_RS10540	COG2814	Major facilitator Superfamily
B7492_RS10545	COG1279	arginine transmembrane transporter activity
B7492_RS10550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS10560	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7492_RS10590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7492_RS10595	COG0577	efflux transmembrane transporter activity
B7492_RS10600	COG2002	toxin-antitoxin pair type II binding
B7492_RS10605	COG1404	Belongs to the peptidase S8 family
B7492_RS10610	COG0640	Transcriptional regulator
B7492_RS10615	COG0667	Aldo Keto reductase
B7492_RS10660	COG3949	Membrane
B7492_RS10665	COG0783	Belongs to the Dps family
B7492_RS10680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7492_RS10690	COG1231	oxidoreductase activity
B7492_RS10695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS10705	COG2267	carboxylic ester hydrolase activity
B7492_RS10710	COG2378	regulation of single-species biofilm formation
B7492_RS10725	COG4989	oxidoreductase activity
B7492_RS10730	COG0523	cobalamin synthesis protein
B7492_RS10735	COG0456	acetyltransferase
B7492_RS10740	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7492_RS10755	COG1902	pentaerythritol trinitrate reductase activity
B7492_RS10760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7492_RS10770	COG4166	transmembrane transport
B7492_RS10775	COG0346	lactoylglutathione lyase activity
B7492_RS10785	COG0406	alpha-ribazole phosphatase activity
B7492_RS10795	COG5337	Spore coat protein CotH
B7492_RS10800	COG1051	belongs to the nudix hydrolase family
B7492_RS10805	COG0586	Pfam SNARE associated Golgi protein
B7492_RS10810	COG2244	polysaccharide biosynthetic process
B7492_RS10820	COG0701	Predicted permease
B7492_RS10825	COG3689	TIGRFAM TIGR03943 family protein
B7492_RS10830	COG1607	acyl-coa hydrolase
B7492_RS10840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7492_RS10860	COG0702	epimerase
B7492_RS10865	COG2839	Protein conserved in bacteria
B7492_RS10870	COG1253	flavin adenine dinucleotide binding
B7492_RS10885	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS10890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7492_RS10910	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7492_RS10925	COG1876	peptidase activity
B7492_RS10935	COG0154	amidase activity
B7492_RS10940	COG2211	Major facilitator Superfamily
B7492_RS10955	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7492_RS10965	COG0561	phosphatase activity
B7492_RS11010	COG1846	Transcriptional regulator
B7492_RS11015	COG1484	DNA-dependent DNA replication
B7492_RS11040	COG3335	DDE superfamily endonuclease
B7492_RS11095	COG0582	viral genome integration into host DNA
B7492_RS11135	COG1802	Transcriptional regulator
B7492_RS11135	COG4626	Terminase
B7492_RS11265	COG1846	Transcriptional regulator
B7492_RS11270	COG2814	Major facilitator Superfamily
B7492_RS11280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7492_RS11300	COG1819	glycosyl
B7492_RS11315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS11345	COG0456	acetyltransferase
B7492_RS11380	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7492_RS11470	COG3874	Sporulation protein YtfJ
B7492_RS11495	COG2226	methyltransferase
B7492_RS11525	COG0604	alcohol dehydrogenase
B7492_RS11530	COG1595	DNA-templated transcription, initiation
B7492_RS11555	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7492_RS11555	COG0426	domain, Protein
B7492_RS11565	COG0386	Belongs to the glutathione peroxidase family
B7492_RS11570	COG1305	Transglutaminase-like
B7492_RS11575	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B7492_RS11580	COG0714	Associated with various cellular activities
B7492_RS11585	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
B7492_RS11590	COG1140	nitrate reductase beta subunit
B7492_RS11595	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
B7492_RS11600	COG2181	nitrate reductase activity
B7492_RS11605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7492_RS11610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7492_RS11615	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7492_RS11620	COG0303	'Molybdopterin
B7492_RS11625	COG0314	molybdopterin synthase activity
B7492_RS11635	COG2223	nitrite transmembrane transporter activity
B7492_RS11645	COG1648	precorrin-2 dehydrogenase activity
B7492_RS11655	COG1587	Uroporphyrinogen-III synthase
B7492_RS11655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7492_RS11660	COG2146	nitrite reductase [NAD(P)H] activity
B7492_RS11665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7492_RS11690	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B7492_RS11720	COG2359	stage V sporulation protein S
B7492_RS11730	COG2856	Zn peptidase
B7492_RS11740	COG0494	nUDIX hydrolase
B7492_RS11770	COG1396	sequence-specific DNA binding
B7492_RS11860	COG0582	viral genome integration into host DNA
B7492_RS11880	COG1418	mRNA catabolic process
B7492_RS11885	COG0488	(ABC) transporter
B7492_RS11900	COG0629	single-stranded DNA binding
B7492_RS11920	COG1413	lyase activity
B7492_RS11940	COG2136	Putative SAM-dependent methyltransferase
B7492_RS11940	COG2521	methyltransferase
B7492_RS11945	COG0018	arginyl-trna synthetase
B7492_RS12005	COG0017	Asparaginyl-tRNA synthetase
B7492_RS12010	COG0733	neurotransmitter:sodium symporter activity
B7492_RS12035	COG2610	gluconate transmembrane transporter activity
B7492_RS12045	COG1794	racemase activity, acting on amino acids and derivatives
B7492_RS12055	COG0456	acetyltransferase
B7492_RS12060	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
B7492_RS12065	COG1131	(ABC) transporter
B7492_RS12070	COG4473	ABC transporter
B7492_RS12080	COG0546	phosphoglycolate phosphatase activity
B7492_RS12100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS12115	COG0768	penicillin binding
B7492_RS12125	COG0204	Acyl-transferase
B7492_RS12130	COG1272	protein, Hemolysin III
B7492_RS12135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B7492_RS12140	COG0805	protein transport
B7492_RS12155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7492_RS12160	COG1999	signal sequence binding
B7492_RS12165	COG0071	Belongs to the small heat shock protein (HSP20) family
B7492_RS12170	COG0367	asparagine synthase
B7492_RS12185	COG0860	N-Acetylmuramoyl-L-alanine amidase
B7492_RS12190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS12195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7492_RS12210	COG3344	reverse transcriptase
B7492_RS12225	COG1335	isochorismatase
B7492_RS12230	COG1051	belongs to the nudix hydrolase family
B7492_RS12235	COG0668	transmembrane transport
B7492_RS12240	COG4585	Histidine kinase
B7492_RS12240	COG2203	Gaf domain
B7492_RS12245	COG2197	response regulator
B7492_RS12250	COG1737	Transcriptional regulator
B7492_RS12255	COG1064	alcohol dehydrogenase
B7492_RS12270	COG1070	Carbohydrate kinase
B7492_RS12280	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B7492_RS12300	COG0517	IMP dehydrogenase activity
B7492_RS12300	COG1125	glycine betaine transport
B7492_RS12305	COG1174	glycine betaine transport
B7492_RS12340	COG1253	flavin adenine dinucleotide binding
B7492_RS12345	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS12350	COG5506	Protein of unknown function (DUF1694)
B7492_RS12365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7492_RS12370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7492_RS12375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7492_RS12380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7492_RS12385	COG0456	acetyltransferase
B7492_RS12390	COG3829	transcription factor binding
B7492_RS12395	COG1509	lysine 2,3-aminomutase activity
B7492_RS12405	COG4479	Belongs to the UPF0346 family
B7492_RS12430	COG4991	sh3 domain protein
B7492_RS12430	COG3064	Membrane
B7492_RS12430	COG0515	serine threonine protein kinase
B7492_RS12440	COG0671	phosphoesterase, PA-phosphatase related
B7492_RS12445	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B7492_RS12450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS12515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7492_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS12565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7492_RS12565	COG4499	WXG100 protein secretion system (Wss), protein YukC
B7492_RS12585	COG0372	Belongs to the citrate synthase family
B7492_RS12590	COG2079	MmgE PrpD family protein
B7492_RS12595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B7492_RS12600	COG1960	acyl-CoA dehydrogenase activity
B7492_RS12605	COG2084	Dehydrogenase
B7492_RS12610	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS12615	COG1280	lysine exporter protein (LysE YggA)
B7492_RS12620	COG1024	Enoyl-CoA hydratase
B7492_RS12635	COG0420	3'-5' exonuclease activity
B7492_RS12650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7492_RS12665	COG2223	nitrite transmembrane transporter activity
B7492_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS12675	COG1169	isochorismate synthase
B7492_RS12680	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7492_RS12685	COG1535	isochorismatase
B7492_RS12685	COG3433	isochorismatase activity
B7492_RS12690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7492_RS12695	COG3251	PFAM MbtH domain protein
B7492_RS12700	COG2814	Major facilitator Superfamily
B7492_RS12715	COG0776	regulation of translation
B7492_RS12725	COG2318	DinB family
B7492_RS12730	COG1115	amino acid carrier protein
B7492_RS12745	COG2329	Antibiotic biosynthesis monooxygenase
B7492_RS12760	COG1187	pseudouridine synthase activity
B7492_RS12765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7492_RS12770	COG3655	Transcriptional regulator
B7492_RS12780	COG1136	(ABC) transporter
B7492_RS12790	COG0596	Alpha beta hydrolase
B7492_RS12805	COG0028	Belongs to the TPP enzyme family
B7492_RS12815	COG2226	methyltransferase
B7492_RS12830	COG1253	flavin adenine dinucleotide binding
B7492_RS12860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7492_RS12890	COG1309	transcriptional regulator
B7492_RS12900	COG0697	spore germination
B7492_RS12905	COG0531	amino acid
B7492_RS12925	COG1247	-acetyltransferase
B7492_RS12970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B7492_RS12980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS13010	COG0583	DNA-binding transcription factor activity
B7492_RS13015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7492_RS13035	COG0583	DNA-binding transcription factor activity
B7492_RS13040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7492_RS13045	COG2258	MOSC domain
B7492_RS13060	COG1132	(ABC) transporter
B7492_RS13065	COG1132	(ABC) transporter
B7492_RS13095	COG1533	DNA photolyase activity
B7492_RS13110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7492_RS13135	COG1396	sequence-specific DNA binding
B7492_RS13165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7492_RS13175	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
B7492_RS13180	COG1595	DNA-templated transcription, initiation
B7492_RS13200	COG1649	PFAM Uncharacterised BCR, COG1649
B7492_RS13220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7492_RS13225	COG2971	BadF BadG BcrA BcrD
B7492_RS13290	COG0500	methyltransferase
B7492_RS13290	COG3615	Tellurite resistance protein tehB
B7492_RS13305	COG0588	phosphoglycerate mutase activity
B7492_RS13330	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7492_RS13340	COG1378	Sugar-specific transcriptional regulator TrmB
B7492_RS13345	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7492_RS13365	COG1136	(ABC) transporter
B7492_RS13385	COG5002	protein histidine kinase activity
B7492_RS13395	COG1686	Belongs to the peptidase S11 family
B7492_RS13420	COG2814	Major facilitator Superfamily
B7492_RS13495	COG0768	penicillin binding
B7492_RS13500	COG1595	DNA-templated transcription, initiation
B7492_RS13510	COG0768	penicillin binding
B7492_RS13515	COG0768	penicillin binding
B7492_RS13555	COG0463	Glycosyl transferase, family 2
B7492_RS13560	COG0463	Glycosyl transferase, family 2
B7492_RS13565	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7492_RS13575	COG1088	dTDP-glucose 4,6-dehydratase activity
B7492_RS13580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7492_RS13585	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
B7492_RS13600	COG2089	acid synthase
B7492_RS13605	COG0772	Belongs to the SEDS family
B7492_RS13610	COG4824	toxin secretion phage lysis holin
B7492_RS13620	COG4641	Protein conserved in bacteria
B7492_RS13635	COG1252	NADH dehydrogenase
B7492_RS13640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS13640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS13655	COG0697	spore germination
B7492_RS13685	COG3397	chitin binding
B7492_RS13690	COG0823	Involved in the tonB-independent uptake of proteins
B7492_RS13700	COG1408	metallophosphoesterase
B7492_RS13710	COG1131	(ABC) transporter
B7492_RS13720	COG1309	transcriptional regulator
B7492_RS13730	COG1960	acyl-CoA dehydrogenase activity
B7492_RS13735	COG0439	Biotin carboxylase
B7492_RS13740	COG0511	ligase activity, forming carbon-carbon bonds
B7492_RS13745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7492_RS13750	COG1024	Enoyl-CoA hydratase
B7492_RS13755	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7492_RS13760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7492_RS13805	COG2318	DinB family
B7492_RS13810	COG1686	Belongs to the peptidase S11 family
B7492_RS13835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7492_RS13880	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS13885	COG1733	regulation of RNA biosynthetic process
B7492_RS13910	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7492_RS13925	COG0697	spore germination
B7492_RS13930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS13965	COG2323	membrane
B7492_RS13980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS13985	COG0697	spore germination
B7492_RS13990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7492_RS13995	COG0201	protein transport
B7492_RS14005	COG0737	Belongs to the 5'-nucleotidase family
B7492_RS14015	COG3227	Zinc metalloprotease (Elastase)
B7492_RS14020	COG1523	belongs to the glycosyl hydrolase 13 family
B7492_RS14040	COG0657	acetylesterase activity
B7492_RS14045	COG1073	alpha beta
B7492_RS14055	COG0577	efflux transmembrane transporter activity
B7492_RS14060	COG1136	(ABC) transporter
B7492_RS14075	COG5002	protein histidine kinase activity
B7492_RS14080	COG0745	RESPONSE REGULATOR receiver
B7492_RS14085	COG1011	Hydrolase
B7492_RS14110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7492_RS14115	COG1183	phosphatidylcholine synthase activity
B7492_RS14125	COG1132	(ABC) transporter
B7492_RS14130	COG3961	Belongs to the TPP enzyme family
B7492_RS14150	COG0322	excinuclease ABC activity
B7492_RS14175	COG2318	DinB family
B7492_RS14190	COG4667	esterase of the alpha-beta hydrolase superfamily
B7492_RS14215	COG3878	Protein conserved in bacteria
B7492_RS14240	COG1051	belongs to the nudix hydrolase family
B7492_RS14245	COG0592	DNA-directed DNA polymerase activity
B7492_RS14250	COG2816	NAD+ diphosphatase activity
B7492_RS14255	COG2223	nitrite transmembrane transporter activity
B7492_RS14260	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS14290	COG0697	spore germination
B7492_RS14295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS14305	COG0584	glycerophosphoryl diester phosphodiesterase
B7492_RS14320	COG1733	regulation of RNA biosynthetic process
B7492_RS14335	COG1132	(ABC) transporter
B7492_RS14335	COG2375	cellular response to nickel ion
B7492_RS14340	COG1132	(ABC) transporter
B7492_RS14375	COG0768	penicillin binding
B7492_RS14380	COG0671	phosphoesterase, PA-phosphatase related
B7492_RS14385	COG0604	alcohol dehydrogenase
B7492_RS14395	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7492_RS14405	COG2205	protein histidine kinase activity
B7492_RS14420	COG1122	ATPase activity
B7492_RS14425	COG4720	Psort location CytoplasmicMembrane, score
B7492_RS14430	COG1794	racemase activity, acting on amino acids and derivatives
B7492_RS14435	COG1819	glycosyl
B7492_RS14445	COG0768	penicillin binding
B7492_RS14450	COG5002	protein histidine kinase activity
B7492_RS14455	COG0561	phosphatase activity
B7492_RS14505	COG2124	cytochrome p450
B7492_RS14560	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7492_RS14570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS14575	COG0460	homoserine dehydrogenase
B7492_RS14595	COG0577	efflux transmembrane transporter activity
B7492_RS14600	COG1136	(ABC) transporter
B7492_RS14610	COG0488	(ABC) transporter
B7492_RS14615	COG0667	Aldo Keto reductase
B7492_RS14620	COG0583	DNA-binding transcription factor activity
B7492_RS14625	COG2205	protein histidine kinase activity
B7492_RS14630	COG0745	RESPONSE REGULATOR receiver
B7492_RS14640	COG3773	Cell wall hydrolase
B7492_RS14645	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
B7492_RS14655	COG0604	alcohol dehydrogenase
B7492_RS14710	COG2959	enzyme of heme biosynthesis
B7492_RS14735	COG3483	tryptophan 2,3-dioxygenase activity
B7492_RS14740	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
B7492_RS14745	COG3844	kynureninase activity
B7492_RS14750	COG1309	transcriptional regulator
B7492_RS14765	COG3284	Transcriptional regulator
B7492_RS14780	COG1349	DNA-binding transcription factor activity
B7492_RS14805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7492_RS14810	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7492_RS14815	COG0022	dehydrogenase e1 component
B7492_RS14820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7492_RS14830	COG2223	nitrite transmembrane transporter activity
B7492_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS14845	COG0456	acetyltransferase
B7492_RS14845	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7492_RS14875	COG4176	ABC-type proline glycine betaine transport system permease component
B7492_RS14880	COG4175	Glycine betaine
B7492_RS14880	COG0517	IMP dehydrogenase activity
B7492_RS14905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
B7492_RS14910	COG2153	protein acetylation
B7492_RS14915	COG3397	chitin binding
B7492_RS14925	COG1819	glycosyl
B7492_RS14940	COG2205	protein histidine kinase activity
B7492_RS14945	COG2315	Protein conserved in bacteria
B7492_RS14990	COG3973	AAA domain
B7492_RS15000	COG2105	PFAM AIG2 family protein
B7492_RS15005	COG0514	ATP-dependent DNA helicase (RecQ)
B7492_RS15025	COG4637	Psort location Cytoplasmic, score
B7492_RS15035	COG1227	inorganic diphosphatase activity
B7492_RS15040	COG3397	chitin binding
B7492_RS15045	COG2318	DinB family
B7492_RS15060	COG1162	GTPase activity
B7492_RS15065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7492_RS15070	COG1115	amino acid carrier protein
B7492_RS15075	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS15080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7492_RS15090	COG3938	Belongs to the proline racemase family
B7492_RS15095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7492_RS15135	COG0586	Pfam SNARE associated Golgi protein
B7492_RS15150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B7492_RS15155	COG4166	transmembrane transport
B7492_RS15165	COG4948	Mandelate Racemase Muconate Lactonizing
B7492_RS15185	COG0667	Aldo Keto reductase
B7492_RS15230	COG2936	dipeptidyl-peptidase activity
B7492_RS15240	COG0745	RESPONSE REGULATOR receiver
B7492_RS15295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7492_RS15300	COG1164	Oligoendopeptidase f
B7492_RS15315	COG1307	EDD domain protein, DegV family
B7492_RS15345	COG1335	isochorismatase
B7492_RS15360	COG2814	Major facilitator Superfamily
B7492_RS15370	COG1664	Polymer-forming cytoskeletal
B7492_RS15375	COG0789	Transcriptional regulator
B7492_RS15380	COG4533	DNA binding
B7492_RS15385	COG0477	Major facilitator Superfamily
B7492_RS15385	COG2814	Major facilitator Superfamily
B7492_RS15415	COG2261	transglycosylase associated protein
B7492_RS15430	COG2226	methyltransferase
B7492_RS15465	COG0436	Aminotransferase
B7492_RS15470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
B7492_RS15495	COG1131	(ABC) transporter
B7492_RS15500	COG2188	Transcriptional regulator
B7492_RS15545	COG0628	permease
B7492_RS15555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7492_RS15560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7492_RS15565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7492_RS15600	COG2746	aminoglycoside 3-N-acetyltransferase activity
B7492_RS15620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7492_RS15625	COG1442	glycosyl transferase family 8
B7492_RS15655	COG0697	spore germination
B7492_RS15690	COG0346	lactoylglutathione lyase activity
B7492_RS15695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS15700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS15720	COG2801	Transposase and inactivated derivatives
B7492_RS15730	COG2323	membrane
B7492_RS15740	COG0596	Alpha beta hydrolase
B7492_RS15745	COG0671	phosphoesterase, PA-phosphatase related
B7492_RS15810	COG2814	Major facilitator Superfamily
B7492_RS15815	COG1368	sulfuric ester hydrolase activity
B7492_RS15825	COG0488	(ABC) transporter
B7492_RS15830	COG1033	growth of symbiont in host cell
B7492_RS15830	COG2409	Drug exporters of the RND superfamily
B7492_RS15835	COG1309	transcriptional regulator
B7492_RS15855	COG0287	Prephenate dehydrogenase
B7492_RS15870	COG1605	Chorismate mutase
B7492_RS15870	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B7492_RS15915	COG3584	3D domain protein
B7492_RS15915	COG1388	LysM domain
B7492_RS15925	COG0346	lactoylglutathione lyase activity
B7492_RS15935	COG0431	NADPH-dependent FMN reductase
B7492_RS15965	COG0579	oxidoreductase
B7492_RS15970	COG1879	ABC-type sugar transport system periplasmic component
B7492_RS15980	COG1172	Belongs to the binding-protein-dependent transport system permease family
B7492_RS15985	COG1129	ABC transporter
B7492_RS15990	COG2390	Transcriptional regulator
B7492_RS16010	COG2226	methyltransferase
B7492_RS16025	COG0346	lactoylglutathione lyase activity
B7492_RS16030	COG2329	Antibiotic biosynthesis monooxygenase
B7492_RS16055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS16060	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B7492_RS16065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B7492_RS16075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7492_RS16080	COG3239	Fatty acid desaturase
B7492_RS16095	COG3655	Transcriptional regulator
B7492_RS16140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS16145	COG0346	lactoylglutathione lyase activity
B7492_RS16170	COG0714	Associated with various cellular activities
B7492_RS16190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7492_RS16195	COG0753	catalase activity
B7492_RS16205	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7492_RS16225	COG0778	Nitroreductase
B7492_RS16230	COG1846	Transcriptional regulator
B7492_RS16250	COG1051	belongs to the nudix hydrolase family
B7492_RS16255	COG2312	Erythromycin esterase
B7492_RS16275	COG2207	Transcriptional regulator
B7492_RS16280	COG0456	acetyltransferase
B7492_RS16300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS16305	COG1671	Belongs to the UPF0178 family
B7492_RS16315	COG0642	Histidine kinase
B7492_RS16320	COG0745	RESPONSE REGULATOR receiver
B7492_RS16325	COG0596	Alpha beta hydrolase
B7492_RS16335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7492_RS16335	COG0456	acetyltransferase
B7492_RS16360	COG0730	response to heat
B7492_RS16370	COG0833	amino acid
B7492_RS16380	COG4335	DNA alkylation repair
B7492_RS16415	COG0768	penicillin binding
B7492_RS16425	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B7492_RS16440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
B7492_RS16445	COG1984	allophanate hydrolase subunit 2
B7492_RS16450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
B7492_RS16455	COG1414	Transcriptional regulator
B7492_RS16475	COG0640	Transcriptional regulator
B7492_RS16485	COG1960	acyl-CoA dehydrogenase activity
B7492_RS16510	COG0640	Transcriptional regulator
B7492_RS16535	COG0574	Belongs to the PEP-utilizing enzyme family
B7492_RS16535	COG3848	Pyruvate phosphate dikinase
B7492_RS16635	COG1063	alcohol dehydrogenase
B7492_RS16655	COG3546	catalase activity
B7492_RS16660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7492_RS16720	COG5002	protein histidine kinase activity
B7492_RS16725	COG0745	RESPONSE REGULATOR receiver
B7492_RS16730	COG0456	acetyltransferase
B7492_RS16735	COG0803	Belongs to the bacterial solute-binding protein 9 family
B7492_RS16740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7492_RS16745	COG1121	(ABC) transporter
B7492_RS16760	COG1999	signal sequence binding
B7492_RS16765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7492_RS16770	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
B7492_RS16795	COG0798	PFAM Bile acid sodium symporter
B7492_RS16800	COG0346	lactoylglutathione lyase activity
B7492_RS16805	COG0640	Transcriptional regulator
B7492_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS16820	COG1522	sequence-specific DNA binding
B7492_RS16835	COG0346	lactoylglutathione lyase activity
B7492_RS16865	COG0745	RESPONSE REGULATOR receiver
B7492_RS16870	COG5002	protein histidine kinase activity
B7492_RS16870	COG3850	Histidine kinase
B7492_RS16900	COG3344	reverse transcriptase
B7492_RS16925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7492_RS16950	COG0673	inositol 2-dehydrogenase activity
B7492_RS16955	COG0673	inositol 2-dehydrogenase activity
B7492_RS16960	COG2169	Transcriptional regulator
B7492_RS16980	COG0789	Transcriptional regulator
B7492_RS17000	COG1136	(ABC) transporter
B7492_RS17005	COG0577	efflux transmembrane transporter activity
B7492_RS17030	COG2801	Transposase and inactivated derivatives
B7492_RS17035	COG3850	Histidine kinase
B7492_RS17035	COG5002	protein histidine kinase activity
B7492_RS17045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS17060	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7492_RS17085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7492_RS17125	COG2814	Major facilitator Superfamily
B7492_RS17235	COG0477	Major facilitator Superfamily
B7492_RS17250	COG1846	Transcriptional regulator
B7492_RS17255	COG2814	Major facilitator Superfamily
B7492_RS17275	COG0640	Transcriptional regulator
B7492_RS17295	COG1329	Transcriptional regulator
B7492_RS17310	COG0697	spore germination
B7492_RS17315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS17390	COG4187	Peptidase family M20/M25/M40
B7492_RS17395	COG1414	Transcriptional regulator
B7492_RS17405	COG0833	amino acid
B7492_RS17415	COG2031	fatty acid transporter
B7492_RS17425	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7492_RS17485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7492_RS17490	COG2356	endonuclease I
B7492_RS17495	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7492_RS17500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7492_RS17525	COG1785	Belongs to the alkaline phosphatase family
B7492_RS17535	COG0778	Nitroreductase
B7492_RS17540	COG1733	regulation of RNA biosynthetic process
B7492_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS17565	COG1131	(ABC) transporter
B7492_RS17595	COG1011	Hydrolase
B7492_RS17600	COG2365	Tyrosine phosphatase family
B7492_RS17625	COG0346	lactoylglutathione lyase activity
B7492_RS17630	COG1940	carbohydrate kinase activity
B7492_RS17635	COG0738	Major facilitator superfamily
B7492_RS17640	COG0110	maltose O-acetyltransferase activity
B7492_RS17655	COG0628	permease
B7492_RS17660	COG2261	transglycosylase associated protein
B7492_RS17690	COG0477	Major facilitator Superfamily
B7492_RS17715	COG1253	flavin adenine dinucleotide binding
B7492_RS17720	COG0789	Transcriptional regulator
B7492_RS17730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7492_RS17755	COG0697	spore germination
B7492_RS17765	COG1357	PFAM Pentapeptide repeats (8 copies)
B7492_RS17770	COG3813	Protein conserved in bacteria
B7492_RS17775	COG2706	6-phosphogluconolactonase activity
B7492_RS17780	COG1070	Carbohydrate kinase
B7492_RS17790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
B7492_RS17795	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B7492_RS17830	COG1393	Belongs to the ArsC family
B7492_RS17840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS17860	COG0384	phenazine biosynthesis protein PhzF
B7492_RS17870	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS17875	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7492_RS17880	COG1733	regulation of RNA biosynthetic process
B7492_RS17905	COG1191	sigma factor activity
B7492_RS17930	COG1876	peptidase activity
B7492_RS17960	COG1073	alpha beta
B7492_RS17985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS17990	COG5577	PFAM Coat F domain
B7492_RS17995	COG2076	Multidrug Resistance protein
B7492_RS18000	COG2076	Multidrug Resistance protein
B7492_RS18030	COG0457	Tetratricopeptide repeat
B7492_RS18065	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7492_RS18075	COG3344	reverse transcriptase
B7492_RS18200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B7492_RS18275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7492_RS18285	COG2801	Transposase and inactivated derivatives
B7492_RS18310	COG0741	lytic transglycosylase activity
B7492_RS18350	COG5002	protein histidine kinase activity
B7492_RS18360	COG3344	reverse transcriptase
B7492_RS18385	COG0657	acetylesterase activity
B7492_RS18395	COG2814	Major facilitator Superfamily
B7492_RS18400	COG1309	transcriptional regulator
B7492_RS18415	COG1280	lysine exporter protein (LysE YggA)
B7492_RS18440	COG0814	amino acid
B7492_RS18465	COG1151	hydroxylamine reductase activity
B7492_RS18490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS18500	COG2072	flavoprotein involved in K transport
B7492_RS18545	COG1695	Transcriptional regulator
B7492_RS18550	COG0604	alcohol dehydrogenase
B7492_RS18555	COG1113	amino acid transport
B7492_RS18565	COG2814	Major facilitator Superfamily
B7492_RS18595	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7492_RS18600	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7492_RS18625	COG3739	integral membrane protein
B7492_RS18645	COG0583	DNA-binding transcription factor activity
B7492_RS18675	COG1193	negative regulation of DNA recombination
B7492_RS18695	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B7492_RS18700	COG1164	Oligoendopeptidase f
B7492_RS18705	COG2957	Belongs to the agmatine deiminase family
B7492_RS18715	COG0789	Transcriptional regulator
B7492_RS18715	COG4978	Transcriptional regulator
B7492_RS18725	COG3781	membrane
B7492_RS18740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS18780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7492_RS18785	COG0640	Transcriptional regulator
B7492_RS18790	COG0604	alcohol dehydrogenase
B7492_RS18795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7492_RS18805	COG0457	Tetratricopeptide repeat
B7492_RS18810	COG2808	Putative FMN-binding domain
B7492_RS18815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7492_RS18825	COG0277	FAD linked oxidase domain protein
B7492_RS18845	COG1285	pathogenesis
B7492_RS18855	COG2514	catechol 2,3-dioxygenase activity
B7492_RS18860	COG2720	vancomycin resistance protein
B7492_RS18885	COG1278	Cold shock
B7492_RS18895	COG0716	FMN binding
B7492_RS18910	COG0494	nUDIX hydrolase
B7492_RS18925	COG3344	reverse transcriptase
B7492_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS18950	COG0165	Argininosuccinate lyase
B7492_RS18965	COG4145	pantothenate transmembrane transporter activity
B7492_RS18975	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS18980	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS18990	COG1657	PFAM Prenyltransferase squalene oxidase
B7492_RS18995	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B7492_RS19000	COG2962	Rard protein
B7492_RS19005	COG3326	Membrane
B7492_RS19040	COG2226	methyltransferase
B7492_RS19045	COG4166	transmembrane transport
B7492_RS19050	COG4166	transmembrane transport
B7492_RS19055	COG4166	transmembrane transport
B7492_RS19065	COG1131	(ABC) transporter
B7492_RS19075	COG0673	inositol 2-dehydrogenase activity
B7492_RS19085	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B7492_RS19090	COG0187	DNA topoisomerase II activity
B7492_RS19095	COG1832	CoA-binding protein
B7492_RS19100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7492_RS19105	COG0745	RESPONSE REGULATOR receiver
B7492_RS19115	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7492_RS19115	COG1328	CTP reductase activity
B7492_RS19125	COG4841	protein insertion into membrane
B7492_RS19130	COG0824	Thioesterase
B7492_RS19155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS19175	COG2274	protein secretion by the type I secretion system
B7492_RS19180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7492_RS19210	COG2211	Major facilitator Superfamily
B7492_RS19220	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7492_RS19235	COG0183	Belongs to the thiolase family
B7492_RS19240	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS19245	COG1268	BioY protein
B7492_RS19250	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS19255	COG1396	sequence-specific DNA binding
B7492_RS19295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS19310	COG5002	protein histidine kinase activity
B7492_RS19320	COG0400	carboxylic ester hydrolase activity
B7492_RS19325	COG0346	lactoylglutathione lyase activity
B7492_RS19335	COG0069	glutamate synthase activity
B7492_RS19340	COG1902	pentaerythritol trinitrate reductase activity
B7492_RS19345	COG1329	Transcriptional regulator
B7492_RS19350	COG0010	Belongs to the arginase family
B7492_RS19360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B7492_RS19365	COG2986	histidine ammonia-lyase
B7492_RS19375	COG2226	methyltransferase
B7492_RS19405	COG4846	Membrane protein involved in cytochrome C biogenesis
B7492_RS19410	COG0785	Cytochrome C biogenesis protein
B7492_RS19420	COG1473	amidohydrolase
B7492_RS19425	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7492_RS19430	COG1131	(ABC) transporter
B7492_RS19440	COG0583	DNA-binding transcription factor activity
B7492_RS19450	COG1346	cytolysis
B7492_RS19465	COG0730	response to heat
B7492_RS19470	COG3409	Peptidoglycan-binding domain 1 protein
B7492_RS19470	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7492_RS19490	COG1132	(ABC) transporter
B7492_RS19495	COG1132	(ABC) transporter
B7492_RS19500	COG3763	UPF0154 protein
B7492_RS19535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7492_RS19540	COG0737	Belongs to the 5'-nucleotidase family
B7492_RS19550	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7492_RS19555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7492_RS19570	COG1695	Transcriptional regulator
B7492_RS19575	COG1132	(ABC) transporter
B7492_RS19600	COG0367	asparagine synthase
B7492_RS19605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7492_RS19615	COG1181	Belongs to the D-alanine--D-alanine ligase family
B7492_RS19620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7492_RS19625	COG3420	alginic acid biosynthetic process
B7492_RS19625	COG5434	Belongs to the glycosyl hydrolase 28 family
B7492_RS19650	COG0438	transferase activity, transferring glycosyl groups
B7492_RS19660	COG0463	Glycosyl transferase, family 2
B7492_RS19660	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7492_RS19665	COG0438	transferase activity, transferring glycosyl groups
B7492_RS19670	COG0438	transferase activity, transferring glycosyl groups
B7492_RS19675	COG1086	Polysaccharide biosynthesis protein
B7492_RS19680	COG0489	protein tyrosine kinase activity
B7492_RS19685	COG3944	biosynthesis protein
B7492_RS19690	COG0174	glutamine synthetase
B7492_RS19695	COG0789	Transcriptional regulator
B7492_RS19700	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B7492_RS19705	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7492_RS19710	COG2860	membrane
B7492_RS19715	COG0464	growth
B7492_RS19740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B7492_RS19750	COG1388	LysM domain
B7492_RS19750	COG3584	3D domain protein
B7492_RS19755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7492_RS19755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7492_RS19755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7492_RS19760	COG1105	Belongs to the carbohydrate kinase PfkB family
B7492_RS19765	COG1349	DNA-binding transcription factor activity
B7492_RS19770	COG1979	alcohol dehydrogenase
B7492_RS19780	COG1979	alcohol dehydrogenase
B7492_RS19785	COG2322	membrane
B7492_RS19795	COG1113	amino acid transport
B7492_RS19810	COG1473	amidohydrolase
B7492_RS19815	COG1408	metallophosphoesterase
B7492_RS19835	COG2217	Heavy metal translocating P-type atpase
B7492_RS19840	COG2608	mercury ion transmembrane transporter activity
B7492_RS19845	COG1937	Protein conserved in bacteria
B7492_RS19865	COG2819	hydrolase of the alpha beta superfamily
B7492_RS19870	COG1120	ATPase activity
B7492_RS19875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS19880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS19885	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS19890	COG0708	Exodeoxyribonuclease III
B7492_RS19895	COG2169	Transcriptional regulator
B7492_RS19900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7492_RS19905	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B7492_RS19910	COG2706	6-phosphogluconolactonase activity
B7492_RS19915	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7492_RS19920	COG2364	Membrane
B7492_RS19930	COG0346	lactoylglutathione lyase activity
B7492_RS19935	COG5001	Diguanylate cyclase
B7492_RS19935	COG3300	MHYT domain
B7492_RS19980	COG1346	cytolysis
B7492_RS19990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7492_RS19995	COG2267	carboxylic ester hydrolase activity
B7492_RS20000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B7492_RS20010	COG2188	Transcriptional regulator
B7492_RS20015	COG2723	6-phospho-beta-galactosidase activity
B7492_RS20020	COG0840	transmembrane signaling receptor activity
B7492_RS20025	COG0823	Involved in the tonB-independent uptake of proteins
B7492_RS20030	COG3773	Cell wall hydrolase
B7492_RS20040	COG1368	sulfuric ester hydrolase activity
B7492_RS20045	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B7492_RS20055	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B7492_RS20060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B7492_RS20070	COG4550	Control of competence regulator ComK, YlbF/YmcA
B7492_RS20075	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7492_RS20080	COG1013	pyruvate-flavodoxin oxidoreductase activity
B7492_RS20085	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B7492_RS20085	COG0674	pyruvate-flavodoxin oxidoreductase activity
B7492_RS20095	COG2359	stage V sporulation protein S
B7492_RS20100	COG1692	metallophosphoesterase
B7492_RS20105	COG1418	mRNA catabolic process
B7492_RS20115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7492_RS20125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B7492_RS20130	COG1058	Belongs to the CinA family
B7492_RS20130	COG1546	Belongs to the CinA family
B7492_RS20135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7492_RS20140	COG1426	Protein conserved in bacteria
B7492_RS20155	COG0300	oxidoreductase activity
B7492_RS20160	COG0612	Peptidase, M16
B7492_RS20165	COG0612	Peptidase, M16
B7492_RS20170	COG1079	Belongs to the binding-protein-dependent transport system permease family
B7492_RS20175	COG4603	Belongs to the binding-protein-dependent transport system permease family
B7492_RS20180	COG3845	ABC transporter
B7492_RS20185	COG1744	ABC transporter substrate-binding protein PnrA-like
B7492_RS20190	COG2188	Transcriptional regulator
B7492_RS20200	COG1674	ftsk spoiiie
B7492_RS20210	COG0740	serine-type endopeptidase activity
B7492_RS20215	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7492_RS20225	COG0527	aspartate kinase activity
B7492_RS20230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B7492_RS20235	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7492_RS20240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7492_RS20245	COG1873	PFAM PRC-barrel domain
B7492_RS20250	COG0612	Peptidase, M16
B7492_RS20255	COG0726	polysaccharide deacetylase
B7492_RS20260	COG1185	polyribonucleotide nucleotidyltransferase activity
B7492_RS20270	COG0196	riboflavin kinase activity
B7492_RS20280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B7492_RS20285	COG1550	Protein conserved in bacteria
B7492_RS20290	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
B7492_RS20295	COG1358	cellular component organization or biogenesis
B7492_RS20300	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B7492_RS20305	COG0195	Participates in both transcription termination and antitermination
B7492_RS20310	COG0779	Required for maturation of 30S ribosomal subunits
B7492_RS20320	COG0442	prolyl-tRNA aminoacylation
B7492_RS20325	COG0750	zinc metalloprotease
B7492_RS20335	COG4589	Belongs to the CDS family
B7492_RS20345	COG0233	cytoplasmic translational termination
B7492_RS20350	COG0528	UMP kinase activity
B7492_RS20355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
B7492_RS20360	COG0052	Belongs to the universal ribosomal protein uS2 family
B7492_RS20365	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B7492_RS20370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
B7492_RS20375	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B7492_RS20380	COG4974	Belongs to the 'phage' integrase family
B7492_RS20385	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B7492_RS20390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7492_RS20395	COG0758	DNA mediated transformation
B7492_RS20400	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B7492_RS20405	COG0045	succinate-CoA ligase (ADP-forming) activity
B7492_RS20410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7492_RS20425	COG0335	large ribosomal subunit rRNA binding
B7492_RS20430	COG0336	Belongs to the RNA methyltransferase TrmD family
B7492_RS20435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7492_RS20440	COG1837	Belongs to the UPF0109 family
B7492_RS20450	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7492_RS20455	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B7492_RS20460	COG0552	protein localization to endoplasmic reticulum
B7492_RS20465	COG1196	nuclear chromosome segregation
B7492_RS20470	COG0571	ribonuclease III activity
B7492_RS20475	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7492_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS20485	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7492_RS20490	COG0416	fatty acid biosynthetic process
B7492_RS20495	COG2050	protein possibly involved in aromatic compounds catabolism
B7492_RS20495	COG1349	DNA-binding transcription factor activity
B7492_RS20500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7492_RS20505	COG1461	Dihydroxyacetone kinase
B7492_RS20510	COG1302	Protein conserved in bacteria
B7492_RS20525	COG1564	THIamine pyrophosphokinase
B7492_RS20530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7492_RS20540	COG2815	serine threonine protein kinase
B7492_RS20540	COG0515	serine threonine protein kinase
B7492_RS20545	COG0631	protein serine/threonine phosphatase activity
B7492_RS20550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B7492_RS20555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7492_RS20555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7492_RS20560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B7492_RS20565	COG0242	peptide deformylase activity
B7492_RS20570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7492_RS20575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7492_RS20580	COG1758	RNA polymerase activity
B7492_RS20595	COG1561	YicC-like family, N-terminal region
B7492_RS20600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7492_RS20615	COG0006	proline dipeptidase activity
B7492_RS20640	COG3069	C4-dicarboxylate transmembrane transporter activity
B7492_RS20660	COG0167	dihydroorotate dehydrogenase activity
B7492_RS20665	COG0543	2 iron, 2 sulfur cluster binding
B7492_RS20670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7492_RS20680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B7492_RS20685	COG0540	Belongs to the ATCase OTCase family
B7492_RS20695	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B7492_RS20700	COG0564	pseudouridine synthase activity
B7492_RS20705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
B7492_RS20715	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7492_RS20720	COG3599	regulation of cell shape
B7492_RS20725	COG2302	S4 RNA-binding domain
B7492_RS20730	COG0762	integral membrane protein
B7492_RS20735	COG1799	cell septum assembly
B7492_RS20740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B7492_RS20750	COG1873	PFAM PRC-barrel domain
B7492_RS20755	COG1191	sigma factor activity
B7492_RS20760	COG1191	sigma factor activity
B7492_RS20770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7492_RS20775	COG0849	cell division
B7492_RS20780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7492_RS20795	COG0772	Belongs to the SEDS family
B7492_RS20800	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
B7492_RS20805	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7492_RS20810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7492_RS20815	COG0768	penicillin binding
B7492_RS20820	COG0768	penicillin binding
B7492_RS20830	COG0275	rRNA processing
B7492_RS20835	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B7492_RS20840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B7492_RS20845	COG0454	-acetyltransferase
B7492_RS20855	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B7492_RS20860	COG1399	metal-binding, possibly nucleic acid-binding protein
B7492_RS20865	COG1323	Belongs to the UPF0348 family
B7492_RS20870	COG3480	Lon protease (S16) C-terminal proteolytic domain
B7492_RS20875	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7492_RS20880	COG3314	Sporulation integral membrane protein YlbJ
B7492_RS20890	COG0742	ribosomal rna small subunit methyltransferase
B7492_RS20900	COG4471	UPF0298 protein
B7492_RS20905	COG3679	Belongs to the UPF0342 family
B7492_RS20910	COG0406	alpha-ribazole phosphatase activity
B7492_RS20925	COG2340	Cysteine-rich secretory protein family
B7492_RS20935	COG3336	cytochrome c oxidase
B7492_RS20960	COG0109	protoheme IX farnesyltransferase activity
B7492_RS20965	COG1612	heme a metabolic process
B7492_RS20970	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B7492_RS20980	COG0772	Belongs to the SEDS family
B7492_RS20985	COG4838	Belongs to the UPF0358 family
B7492_RS20990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B7492_RS20995	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B7492_RS21005	COG4896	Protein conserved in bacteria
B7492_RS21020	COG1217	gtp-binding protein TYPA
B7492_RS21030	COG0483	inositol monophosphate 1-phosphatase activity
B7492_RS21040	COG4493	Belongs to the UPF0637 family
B7492_RS21045	COG4476	Belongs to the UPF0223 family
B7492_RS21050	COG1982	Orn Lys Arg decarboxylase major
B7492_RS21100	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7492_RS21105	COG0022	dehydrogenase e1 component
B7492_RS21110	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7492_RS21125	COG0561	phosphatase activity
B7492_RS21135	COG5503	Protein of unknown function (DUF1447)
B7492_RS21140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B7492_RS21145	COG0569	domain protein
B7492_RS21155	COG1473	amidohydrolase
B7492_RS21160	COG2171	N-acyltransferase activity
B7492_RS21165	COG0583	DNA-binding transcription factor activity
B7492_RS21170	COG0517	IMP dehydrogenase activity
B7492_RS21180	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B7492_RS21185	COG4703	Protein of unknown function (DUF1797)
B7492_RS21200	COG2200	EAL domain
B7492_RS21205	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS21210	COG1408	metallophosphoesterase
B7492_RS21255	COG2814	Major facilitator Superfamily
B7492_RS21265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
B7492_RS21275	COG3209	COG3209 Rhs family protein
B7492_RS21285	COG2205	protein histidine kinase activity
B7492_RS21295	COG0436	Aminotransferase
B7492_RS21305	COG1609	Transcriptional regulator
B7492_RS21310	COG3833	ABC-type maltose transport systems, permease component
B7492_RS21315	COG1175	transmembrane transport
B7492_RS21320	COG2182	Extracellular solute-binding protein
B7492_RS21330	COG0366	Alpha amylase catalytic
B7492_RS21335	COG3842	ATPase activity
B7492_RS21375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7492_RS21380	COG0183	Belongs to the thiolase family
B7492_RS21415	COG1695	Transcriptional regulator
B7492_RS21420	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS21430	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
B7492_RS21435	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
B7492_RS21440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7492_RS21445	COG0436	Aminotransferase
B7492_RS21450	COG1850	ribulose-bisphosphate carboxylase activity
B7492_RS21455	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
B7492_RS21460	COG0235	Class ii aldolase
B7492_RS21465	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
B7492_RS21480	COG2084	Dehydrogenase
B7492_RS21490	COG2199	diguanylate cyclase activity
B7492_RS21495	COG0778	Nitroreductase
B7492_RS21520	COG2190	(PTS) system
B7492_RS21520	COG1263	PTS System
B7492_RS21520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B7492_RS21525	COG3711	transcriptional antiterminator
B7492_RS21535	COG2188	Transcriptional regulator
B7492_RS21540	COG0363	glucosamine-6-phosphate deaminase activity
B7492_RS21545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B7492_RS21555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7492_RS21565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7492_RS21575	COG1547	Domain of unknown function (DUF309)
B7492_RS21585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7492_RS21590	COG4086	secreted protein
B7492_RS21595	COG0561	phosphatase activity
B7492_RS21600	COG0697	spore germination
B7492_RS21615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7492_RS21655	COG1686	Belongs to the peptidase S11 family
B7492_RS21660	COG1725	Transcriptional regulator
B7492_RS21665	COG1131	(ABC) transporter
B7492_RS21685	COG1846	Transcriptional regulator
B7492_RS21700	COG0598	Magnesium transport protein CorA
B7492_RS21715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B7492_RS21725	COG4974	Belongs to the 'phage' integrase family
B7492_RS21735	COG0735	belongs to the Fur family
B7492_RS21740	COG1300	Membrane
B7492_RS21760	COG0667	Aldo Keto reductase
B7492_RS21765	COG0656	L-ascorbic acid biosynthetic process
B7492_RS21770	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7492_RS21770	COG0456	acetyltransferase
B7492_RS21780	COG4085	toxin activity
B7492_RS21780	COG1525	nuclease
B7492_RS21780	COG0737	Belongs to the 5'-nucleotidase family
B7492_RS21785	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B7492_RS21795	COG0596	Alpha beta hydrolase
B7492_RS21800	COG2056	Na+-H+ antiporter family
B7492_RS21805	COG1609	Transcriptional regulator
B7492_RS21810	COG0456	acetyltransferase
B7492_RS21815	COG1073	alpha beta
B7492_RS21830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7492_RS21830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7492_RS21835	COG0307	riboflavin synthase, alpha
B7492_RS21840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7492_RS21840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7492_RS21855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
B7492_RS21860	COG4106	trans-aconitate 2-methyltransferase activity
B7492_RS21865	COG1073	alpha beta
B7492_RS21865	COG2226	methyltransferase
B7492_RS21870	COG0156	8-amino-7-oxononanoate synthase activity
B7492_RS21880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B7492_RS21895	COG1757	Na H antiporter
B7492_RS21900	COG0737	Belongs to the 5'-nucleotidase family
B7492_RS21910	COG1522	sequence-specific DNA binding
B7492_RS21945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B7492_RS21955	COG0300	oxidoreductase activity
B7492_RS21960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS21965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7492_RS21970	COG1760	l-serine dehydratase
B7492_RS21975	COG1760	l-serine dehydratase
B7492_RS21985	COG1234	tRNA 3'-trailer cleavage
B7492_RS22010	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7492_RS22015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS22025	COG1376	ErfK ybiS ycfS ynhG family protein
B7492_RS22030	COG4129	membrane
B7492_RS22035	COG1126	abc transporter atp-binding protein
B7492_RS22040	COG0765	amino acid transport
B7492_RS22045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7492_RS22055	COG2816	NAD+ diphosphatase activity
B7492_RS22060	COG2323	membrane
B7492_RS22065	COG0772	Belongs to the SEDS family
B7492_RS22070	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7492_RS22075	COG0022	dehydrogenase e1 component
B7492_RS22080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7492_RS22085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7492_RS22090	COG3426	butyrate kinase activity
B7492_RS22100	COG0280	phosphate acetyltransferase
B7492_RS22110	COG3829	transcription factor binding
B7492_RS22110	COG3290	protein histidine kinase activity
B7492_RS22120	COG0584	glycerophosphoryl diester phosphodiesterase
B7492_RS22125	COG3093	addiction module antidote protein HigA
B7492_RS22135	COG0745	RESPONSE REGULATOR receiver
B7492_RS22145	COG0750	zinc metalloprotease
B7492_RS22150	COG0497	DNA recombination
B7492_RS22155	COG1438	arginine binding
B7492_RS22160	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B7492_RS22165	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B7492_RS22170	COG0142	geranyltranstransferase activity
B7492_RS22175	COG1722	exodeoxyribonuclease VII activity
B7492_RS22180	COG1570	exodeoxyribonuclease VII activity
B7492_RS22185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B7492_RS22190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B7492_RS22195	COG1302	Protein conserved in bacteria
B7492_RS22200	COG0439	Biotin carboxylase
B7492_RS22205	COG0511	ligase activity, forming carbon-carbon bonds
B7492_RS22250	COG3854	ATPases associated with a variety of cellular activities
B7492_RS22270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B7492_RS22275	COG0006	proline dipeptidase activity
B7492_RS22280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B7492_RS22290	COG3872	metal-dependent enzyme
B7492_RS22300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7492_RS22305	COG1321	iron dependent repressor
B7492_RS22340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS22350	COG1609	Transcriptional regulator
B7492_RS22360	COG2076	Multidrug Resistance protein
B7492_RS22365	COG2076	Multidrug Resistance protein
B7492_RS22400	COG1725	Transcriptional regulator
B7492_RS22415	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7492_RS22420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B7492_RS22425	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B7492_RS22430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7492_RS22460	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B7492_RS22555	COG5297	Belongs to the glycosyl hydrolase family 6
B7492_RS22555	COG4733	cellulase activity
B7492_RS22565	COG0740	serine-type endopeptidase activity
B7492_RS22575	COG4626	Terminase
B7492_RS22575	COG1802	Transcriptional regulator
B7492_RS22615	COG0582	viral genome integration into host DNA
B7492_RS22685	COG2002	toxin-antitoxin pair type II binding
B7492_RS22740	COG3620	sequence-specific DNA binding
B7492_RS22765	COG4970	Tfp pilus assembly protein FimT
B7492_RS22775	COG1459	type II secretion system
B7492_RS22780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B7492_RS22835	COG1410	methionine synthase
B7492_RS22835	COG0646	methionine synthase
B7492_RS22840	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7492_RS22840	COG0646	methionine synthase
B7492_RS22845	COG0626	cystathionine gamma-synthase activity
B7492_RS22850	COG0626	cystathionine gamma-synthase activity
B7492_RS22865	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS22875	COG1940	carbohydrate kinase activity
B7492_RS22880	COG4483	Protein conserved in bacteria
B7492_RS22885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7492_RS22890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B7492_RS22895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7492_RS22900	COG0704	Plays a role in the regulation of phosphate uptake
B7492_RS22910	COG0581	inorganic phosphate transmembrane transporter activity
B7492_RS22915	COG0573	inorganic phosphate transmembrane transporter activity
B7492_RS22920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7492_RS22925	COG0768	penicillin binding
B7492_RS22930	COG0477	Major facilitator Superfamily
B7492_RS22935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7492_RS22960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B7492_RS22965	COG0735	belongs to the Fur family
B7492_RS22970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7492_RS22975	COG1121	(ABC) transporter
B7492_RS22980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS22990	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B7492_RS23005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B7492_RS23010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7492_RS23015	COG2384	SAM-dependent methyltransferase
B7492_RS23025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B7492_RS23030	COG0358	DNA primase activity
B7492_RS23040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B7492_RS23045	COG0517	IMP dehydrogenase activity
B7492_RS23050	COG1381	Involved in DNA repair and RecF pathway recombination
B7492_RS23060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7492_RS23065	COG0295	cytidine deaminase activity
B7492_RS23070	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B7492_RS23075	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B7492_RS23080	COG1480	7TM receptor with intracellular HD hydrolase
B7492_RS23085	COG1702	phosphate starvation-inducible protein PhoH
B7492_RS23100	COG1610	YqeY-like protein
B7492_RS23105	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B7492_RS23110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B7492_RS23115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7492_RS23125	COG0484	heat shock protein binding
B7492_RS23130	COG0443	Heat shock 70 kDa protein
B7492_RS23140	COG1420	regulation of RNA biosynthetic process
B7492_RS23145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7492_RS23150	COG1733	regulation of RNA biosynthetic process
B7492_RS23155	COG0481	GTPase activity
B7492_RS23165	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B7492_RS23170	COG0268	Binds directly to 16S ribosomal RNA
B7492_RS23175	COG1466	dna polymerase III delta subunit
B7492_RS23185	COG2333	competence protein COMEC
B7492_RS23185	COG0658	competence protein
B7492_RS23190	COG2131	deaminase
B7492_RS23195	COG1555	photosystem II stabilization
B7492_RS23195	COG1596	polysaccharide export
B7492_RS23200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B7492_RS23205	COG2226	methyltransferase
B7492_RS23210	COG0799	negative regulation of ribosome biogenesis
B7492_RS23215	COG1713	HD superfamily hydrolase involved in NAD metabolism
B7492_RS23220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B7492_RS23225	COG1534	Rna-binding protein
B7492_RS23230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B7492_RS23235	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B7492_RS23240	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B7492_RS23250	COG0688	phosphatidylethanolamine metabolic process
B7492_RS23265	COG1595	DNA-templated transcription, initiation
B7492_RS23270	COG2357	RelA SpoT domain protein
B7492_RS23280	COG1785	Belongs to the alkaline phosphatase family
B7492_RS23290	COG2267	carboxylic ester hydrolase activity
B7492_RS23325	COG1404	Belongs to the peptidase S8 family
B7492_RS23330	COG3186	Phenylalanine-4-hydroxylase
B7492_RS23335	COG2154	pterin-4-alpha-carbinolamine dehydratase
B7492_RS23345	COG2514	catechol 2,3-dioxygenase activity
B7492_RS23350	COG2259	Doxx family
B7492_RS23390	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS23405	COG1454	alcohol dehydrogenase
B7492_RS23405	COG1012	belongs to the aldehyde dehydrogenase family
B7492_RS23410	COG0626	cystathionine gamma-synthase activity
B7492_RS23415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7492_RS23420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7492_RS23425	COG2226	methyltransferase
B7492_RS23440	COG0768	penicillin binding
B7492_RS23445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7492_RS23450	COG0572	uridine kinase
B7492_RS23455	COG0826	peptidase U32
B7492_RS23460	COG0826	peptidase U32
B7492_RS23465	COG4122	O-methyltransferase activity
B7492_RS23470	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7492_RS23480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7492_RS23485	COG4472	Bacterial protein of unknown function (DUF965)
B7492_RS23490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B7492_RS23500	COG0628	permease
B7492_RS23520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7492_RS23530	COG0482	sulfurtransferase activity
B7492_RS23535	COG1104	cysteine desulfurase activity
B7492_RS23540	COG1959	2 iron, 2 sulfur cluster binding
B7492_RS23545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7492_RS23555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7492_RS23560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B7492_RS23570	COG1490	D-aminoacyl-tRNA deacylase activity
B7492_RS23575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7492_RS23580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B7492_RS23585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7492_RS23585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B7492_RS23590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B7492_RS23595	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7492_RS23595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7492_RS23605	COG2244	polysaccharide biosynthetic process
B7492_RS23610	COG2323	membrane
B7492_RS23620	COG1862	Preprotein translocase
B7492_RS23625	COG0343	queuine tRNA-ribosyltransferase activity
B7492_RS23630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B7492_RS23640	COG2255	four-way junction helicase activity
B7492_RS23645	COG0632	four-way junction helicase activity
B7492_RS23650	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
B7492_RS23675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7492_RS23680	COG0157	Belongs to the NadC ModD family
B7492_RS23685	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B7492_RS23690	COG1104	cysteine desulfurase activity
B7492_RS23695	COG1827	regulation of RNA biosynthetic process
B7492_RS23700	COG2258	MOSC domain
B7492_RS23705	COG0077	Prephenate dehydratase
B7492_RS23710	COG0577	efflux transmembrane transporter activity
B7492_RS23715	COG0577	efflux transmembrane transporter activity
B7492_RS23720	COG1136	(ABC) transporter
B7492_RS23725	COG5002	protein histidine kinase activity
B7492_RS23730	COG0745	RESPONSE REGULATOR receiver
B7492_RS23735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B7492_RS23740	COG3290	protein histidine kinase activity
B7492_RS23750	COG2868	ribosomal protein
B7492_RS23760	COG1530	ribonuclease E activity
B7492_RS23765	COG1994	Peptidase M50
B7492_RS23770	COG0739	heme binding
B7492_RS23775	COG2894	cell division
B7492_RS23780	COG0850	regulation of cytokinetic process
B7492_RS23795	COG1077	Cell shape determining protein MreB Mrl
B7492_RS23800	COG2003	Belongs to the UPF0758 family
B7492_RS23835	COG2003	Belongs to the UPF0758 family
B7492_RS23840	COG0424	maF-like protein
B7492_RS23855	COG0285	dihydrofolate synthase activity
B7492_RS23870	COG1388	LysM domain
B7492_RS23875	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B7492_RS23880	COG0113	porphobilinogen synthase activity
B7492_RS23885	COG1587	Uroporphyrinogen-III synthase
B7492_RS23890	COG0181	hydroxymethylbilane synthase activity
B7492_RS23895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B7492_RS23900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
B7492_RS23905	COG1846	Transcriptional regulator
B7492_RS23910	COG1764	response to oxidative stress
B7492_RS23915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B7492_RS23925	COG1067	ATP-dependent peptidase activity
B7492_RS23925	COG0470	DNA polymerase III
B7492_RS23935	COG0544	peptidyl-prolyl cis-trans isomerase activity
B7492_RS23965	COG0622	Phosphoesterase
B7492_RS23975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B7492_RS23980	COG5401	PFAM Sporulation and spore germination
B7492_RS23990	COG2197	response regulator
B7492_RS23995	COG2233	PERMEase
B7492_RS24000	COG0402	S-adenosylhomocysteine deaminase activity
B7492_RS24005	COG1983	PspC domain protein
B7492_RS24010	COG1396	sequence-specific DNA binding
B7492_RS24015	COG0697	spore germination
B7492_RS24025	COG1959	2 iron, 2 sulfur cluster binding
B7492_RS24030	COG1668	transmembrane transport
B7492_RS24035	COG4152	abc transporter atp-binding protein
B7492_RS24040	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B7492_RS24045	COG1360	Flagellar Motor Protein
B7492_RS24050	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B7492_RS24060	COG1876	peptidase activity
B7492_RS24065	COG0824	Thioesterase
B7492_RS24070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7492_RS24075	COG1053	succinate dehydrogenase
B7492_RS24080	COG2009	succinate dehydrogenase
B7492_RS24085	COG1719	4-vinyl reductase, 4VR
B7492_RS24090	COG0322	excinuclease ABC activity
B7492_RS24095	COG3118	belongs to the thioredoxin family
B7492_RS24100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B7492_RS24105	COG2086	electron transfer activity
B7492_RS24110	COG1024	Enoyl-CoA hydratase
B7492_RS24115	COG1309	transcriptional regulator
B7492_RS24120	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS24140	COG2318	DinB family
B7492_RS24165	COG1131	(ABC) transporter
B7492_RS24170	COG2205	protein histidine kinase activity
B7492_RS24175	COG0745	RESPONSE REGULATOR receiver
B7492_RS24180	COG4895	conserved protein (DUF2196)
B7492_RS24185	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B7492_RS24190	COG2329	Antibiotic biosynthesis monooxygenase
B7492_RS24195	COG4509	Sortase family
B7492_RS24200	COG1120	ATPase activity
B7492_RS24215	COG5386	Cell surface protein
B7492_RS24225	COG5386	Cell surface protein
B7492_RS24230	COG1114	Component of the transport system for branched-chain amino acids
B7492_RS24240	COG1193	negative regulation of DNA recombination
B7492_RS24245	COG1796	DNA polymerase
B7492_RS24245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B7492_RS24250	COG1286	toxin biosynthetic process
B7492_RS24255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B7492_RS24260	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7492_RS24285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B7492_RS24290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7492_RS24300	COG1418	mRNA catabolic process
B7492_RS24320	COG2814	Major facilitator Superfamily
B7492_RS24325	COG1566	PFAM secretion protein HlyD family protein
B7492_RS24330	COG1309	transcriptional regulator
B7492_RS24335	COG1363	Peptidase, m42
B7492_RS24345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7492_RS24360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B7492_RS24370	COG1484	DNA-dependent DNA replication
B7492_RS24375	COG3611	Membrane attachment protein
B7492_RS24380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B7492_RS24385	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B7492_RS24390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7492_RS24395	COG0237	dephospho-CoA kinase activity
B7492_RS24400	COG1971	Probably functions as a manganese efflux pump
B7492_RS24410	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7492_RS24410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B7492_RS24415	COG5002	protein histidine kinase activity
B7492_RS24420	COG0745	RESPONSE REGULATOR receiver
B7492_RS24435	COG0039	L-malate dehydrogenase activity
B7492_RS24440	COG0538	isocitrate dehydrogenase activity
B7492_RS24445	COG0372	Belongs to the citrate synthase family
B7492_RS24460	COG0628	permease
B7492_RS24465	COG3030	protein affecting phage T7 exclusion by the F plasmid
B7492_RS24475	COG0205	6-phosphofructokinase activity
B7492_RS24485	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B7492_RS24490	COG1725	Transcriptional regulator
B7492_RS24495	COG0281	malic enzyme
B7492_RS24500	COG0587	DNA-directed DNA polymerase activity
B7492_RS24515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B7492_RS24535	COG4109	DRTGG domain
B7492_RS24540	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B7492_RS24545	COG0006	proline dipeptidase activity
B7492_RS24585	COG0662	Cupin 2, conserved barrel domain protein
B7492_RS24590	COG1476	TRANSCRIPTIONal
B7492_RS24605	COG1028	Short-chain dehydrogenase reductase Sdr
B7492_RS24610	COG0589	response to stress
B7492_RS24625	COG0165	Argininosuccinate lyase
B7492_RS24630	COG0137	argininosuccinate synthase activity
B7492_RS24645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS24660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7492_RS24665	COG0827	DNA restriction-modification system
B7492_RS24670	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B7492_RS24675	COG3874	Sporulation protein YtfJ
B7492_RS24695	COG1574	metal-dependent hydrolase with the TIM-barrel fold
B7492_RS24705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7492_RS24720	COG1104	cysteine desulfurase activity
B7492_RS24730	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B7492_RS24740	COG0697	spore germination
B7492_RS24745	COG1309	transcriptional regulator
B7492_RS24750	COG1956	GAF domain-containing protein
B7492_RS24755	COG0626	cystathionine gamma-synthase activity
B7492_RS24765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B7492_RS24900	COG1595	DNA-templated transcription, initiation
B7492_RS24910	COG0110	maltose O-acetyltransferase activity
B7492_RS24915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7492_RS24920	COG0454	-acetyltransferase
B7492_RS24925	COG0517	IMP dehydrogenase activity
B7492_RS24930	COG0123	including yeast histone deacetylase and acetoin utilization protein
B7492_RS24950	COG0745	RESPONSE REGULATOR receiver
B7492_RS24955	COG5002	protein histidine kinase activity
B7492_RS24960	COG0666	response to abiotic stimulus
B7492_RS24970	COG1970	mechanosensitive ion channel activity
B7492_RS24995	COG1609	Transcriptional regulator
B7492_RS25005	COG4851	CamS sex pheromone cAM373 precursor
B7492_RS25010	COG3118	belongs to the thioredoxin family
B7492_RS25020	COG2309	aminopeptidase activity
B7492_RS25045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7492_RS25055	COG1674	ftsk spoiiie
B7492_RS25070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7492_RS25075	COG4848	Belongs to the UPF0354 family
B7492_RS25080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS25085	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B7492_RS25090	COG1363	Peptidase, m42
B7492_RS25100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS25105	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7492_RS25115	COG0510	thiamine kinase activity
B7492_RS25120	COG1523	belongs to the glycosyl hydrolase 13 family
B7492_RS25130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B7492_RS25135	COG1349	DNA-binding transcription factor activity
B7492_RS25140	COG1187	pseudouridine synthase activity
B7492_RS25145	COG2244	polysaccharide biosynthetic process
B7492_RS25150	COG2081	HI0933 family
B7492_RS25160	COG2814	Major facilitator Superfamily
B7492_RS25170	COG3832	glyoxalase III activity
B7492_RS25190	COG1329	Transcriptional regulator
B7492_RS25215	COG0314	molybdopterin synthase activity
B7492_RS25220	COG1763	Mo-molybdopterin cofactor biosynthetic process
B7492_RS25225	COG0303	'Molybdopterin
B7492_RS25230	COG0315	cyclic pyranopterin monophosphate synthase activity
B7492_RS25235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B7492_RS25240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7492_RS25265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B7492_RS25275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7492_RS25315	COG0495	leucyl-tRNA aminoacylation
B7492_RS25320	COG2814	Major facilitator Superfamily
B7492_RS25325	COG0475	glutathione-regulated potassium exporter activity
B7492_RS25330	COG0490	domain, Protein
B7492_RS25335	COG0582	viral genome integration into host DNA
B7492_RS25345	COG1136	(ABC) transporter
B7492_RS25365	COG1242	4 iron, 4 sulfur cluster binding
B7492_RS25370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B7492_RS25375	COG1131	(ABC) transporter
B7492_RS25385	COG1794	racemase activity, acting on amino acids and derivatives
B7492_RS25400	COG2267	carboxylic ester hydrolase activity
B7492_RS25405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7492_RS25410	COG0671	phosphoesterase, PA-phosphatase related
B7492_RS25415	COG0438	transferase activity, transferring glycosyl groups
B7492_RS25420	COG0746	molybdenum cofactor guanylyltransferase activity
B7492_RS25440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B7492_RS25445	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
B7492_RS25470	COG5002	protein histidine kinase activity
B7492_RS25475	COG3852	Histidine kinase
B7492_RS25480	COG0753	catalase activity
B7492_RS25485	COG2267	carboxylic ester hydrolase activity
B7492_RS25500	COG1368	sulfuric ester hydrolase activity
B7492_RS25510	COG4895	conserved protein (DUF2196)
B7492_RS25525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7492_RS25530	COG1116	anion transmembrane transporter activity
B7492_RS25535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7492_RS25560	COG0494	nUDIX hydrolase
B7492_RS25610	COG2076	Multidrug Resistance protein
B7492_RS25615	COG2076	Multidrug Resistance protein
B7492_RS25620	COG0789	Transcriptional regulator
B7492_RS25625	COG1854	S-ribosylhomocysteine lyase activity
B7492_RS25635	COG0288	reversible hydration of carbon dioxide
B7492_RS25640	COG1271	oxidase subunit
B7492_RS25665	COG3409	Peptidoglycan-binding domain 1 protein
B7492_RS25665	COG1388	LysM domain
B7492_RS25665	COG5632	N-Acetylmuramoyl-L-alanine amidase
B7492_RS25670	COG4824	toxin secretion phage lysis holin
B7492_RS25680	COG3344	reverse transcriptase
B7492_RS25750	COG0740	serine-type endopeptidase activity
B7492_RS25760	COG4626	Terminase
B7492_RS25760	COG1802	Transcriptional regulator
B7492_RS25805	COG0582	viral genome integration into host DNA
B7492_RS25865	COG1484	DNA-dependent DNA replication
B7492_RS25870	COG1846	Transcriptional regulator
B7492_RS25905	COG1396	sequence-specific DNA binding
B7492_RS25920	COG1271	oxidase subunit
B7492_RS25925	COG1294	oxidase, subunit
B7492_RS25945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS25970	COG1842	Phage shock protein A
B7492_RS25995	COG3859	Proton-coupled thiamine transporter YuaJ
B7492_RS26000	COG5002	protein histidine kinase activity
B7492_RS26005	COG0745	RESPONSE REGULATOR receiver
B7492_RS26030	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B7492_RS26035	COG1597	lipid kinase activity
B7492_RS26050	COG1136	(ABC) transporter
B7492_RS26090	COG5002	protein histidine kinase activity
B7492_RS26105	COG4977	sequence-specific DNA binding
B7492_RS26115	COG0577	efflux transmembrane transporter activity
B7492_RS26120	COG1136	(ABC) transporter
B7492_RS26125	COG2207	Transcriptional regulator
B7492_RS26125	COG3708	Transcriptional regulator
B7492_RS26135	COG1131	(ABC) transporter
B7492_RS26140	COG5658	integral membrane protein
B7492_RS26145	COG0640	Transcriptional regulator
B7492_RS26150	COG0745	RESPONSE REGULATOR receiver
B7492_RS26155	COG2205	protein histidine kinase activity
B7492_RS26160	COG0577	efflux transmembrane transporter activity
B7492_RS26165	COG0577	efflux transmembrane transporter activity
B7492_RS26170	COG1136	(ABC) transporter
B7492_RS26175	COG0577	efflux transmembrane transporter activity
B7492_RS26190	COG2188	Transcriptional regulator
B7492_RS26210	COG3964	amidohydrolase
B7492_RS26230	COG4948	Mandelate Racemase Muconate Lactonizing
B7492_RS26235	COG0318	PFAM AMP-dependent synthetase and ligase
B7492_RS26240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B7492_RS26245	COG0596	Alpha beta hydrolase
B7492_RS26250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B7492_RS26255	COG1169	isochorismate synthase
B7492_RS26260	COG1575	Belongs to the MenA family. Type 1 subfamily
B7492_RS26265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7492_RS26270	COG1278	Cold shock
B7492_RS26285	COG0789	Transcriptional regulator
B7492_RS26295	COG0058	SHG alpha-glucan phosphorylase activity
B7492_RS26305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B7492_RS26310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B7492_RS26315	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
B7492_RS26335	COG1595	DNA-templated transcription, initiation
B7492_RS26475	COG1285	pathogenesis
B7492_RS26480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7492_RS26490	COG0166	Belongs to the GPI family
B7492_RS26500	COG2155	Conserved Protein
B7492_RS26505	COG1098	S1 RNA binding domain
B7492_RS26510	COG0436	Aminotransferase
B7492_RS26515	COG1522	sequence-specific DNA binding
B7492_RS26520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B7492_RS26525	COG2267	carboxylic ester hydrolase activity
B7492_RS26535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B7492_RS26550	COG5018	Exonuclease
B7492_RS26555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7492_RS26575	COG2050	protein possibly involved in aromatic compounds catabolism
B7492_RS26585	COG1268	BioY protein
B7492_RS26590	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7492_RS26595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7492_RS26605	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B7492_RS26610	COG3584	3D domain protein
B7492_RS26625	COG1252	NADH dehydrogenase
B7492_RS26630	COG0492	ferredoxin-NADP+ reductase activity
B7492_RS26635	COG3708	Transcriptional regulator
B7492_RS26650	COG1683	Conserved Protein
B7492_RS26670	COG0316	Belongs to the HesB IscA family
B7492_RS26675	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B7492_RS26680	COG4844	belongs to the
B7492_RS26685	COG1252	NADH dehydrogenase
B7492_RS26690	COG2274	protein secretion by the type I secretion system
B7492_RS26695	COG0390	transport system, permease component
B7492_RS26700	COG2824	Alkylphosphonate utilization operon protein PhnA
B7492_RS26715	COG4837	Protein of unknown function (DUF1462)
B7492_RS26720	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B7492_RS26745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7492_RS26750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7492_RS26770	COG0577	efflux transmembrane transporter activity
B7492_RS26770	COG1136	(ABC) transporter
B7492_RS26775	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7492_RS26785	COG0647	UMP catabolic process
B7492_RS26795	COG2445	Protein of unknown function DUF86
B7492_RS26800	COG1494	fructose-1,6-bisphosphatase
B7492_RS26825	COG4470	Protein conserved in bacteria
B7492_RS26835	COG0789	Transcriptional regulator
B7492_RS26840	COG4377	Putative membrane peptidase family (DUF2324)
B7492_RS26860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7492_RS26865	COG0739	heme binding
B7492_RS26875	COG3377	Domain of unknown function (DUF1805)
B7492_RS26880	COG0737	Belongs to the 5'-nucleotidase family
B7492_RS26885	COG0719	Fe-S assembly protein
B7492_RS26890	COG0822	iron-sulfur transferase activity
B7492_RS26895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7492_RS26900	COG0719	Fe-S assembly protein
B7492_RS26905	COG0396	ATPase activity
B7492_RS26910	COG1464	Belongs to the NlpA lipoprotein family
B7492_RS26915	COG1464	Belongs to the NlpA lipoprotein family
B7492_RS26920	COG2011	ABC-type metal ion transport system permease component
B7492_RS26940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS26945	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B7492_RS26950	COG0509	glycine decarboxylation via glycine cleavage system
B7492_RS26955	COG1393	Belongs to the ArsC family
B7492_RS27000	COG1309	transcriptional regulator
B7492_RS27005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7492_RS27010	COG1960	acyl-CoA dehydrogenase activity
B7492_RS27015	COG0183	Belongs to the thiolase family
B7492_RS27020	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7492_RS27020	COG1024	Enoyl-CoA hydratase
B7492_RS27030	COG1686	Belongs to the peptidase S11 family
B7492_RS27045	COG0011	TIGRFAM Protein of
B7492_RS27050	COG0840	transmembrane signaling receptor activity
B7492_RS27060	COG2814	Major facilitator Superfamily
B7492_RS27065	COG0531	amino acid
B7492_RS27090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B7492_RS27165	COG0586	Pfam SNARE associated Golgi protein
B7492_RS27175	COG1376	ErfK ybiS ycfS ynhG family protein
B7492_RS27180	COG0745	RESPONSE REGULATOR receiver
B7492_RS27185	COG5002	protein histidine kinase activity
B7492_RS27195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7492_RS27205	COG0840	transmembrane signaling receptor activity
B7492_RS27210	COG0840	transmembrane signaling receptor activity
B7492_RS27215	COG2151	metal-sulfur cluster biosynthetic enzyme
B7492_RS27220	COG3227	Zinc metalloprotease (Elastase)
B7492_RS27225	COG1741	Belongs to the pirin family
B7492_RS27240	COG0586	Pfam SNARE associated Golgi protein
B7492_RS27245	COG0475	glutathione-regulated potassium exporter activity
B7492_RS27250	COG0490	domain, Protein
B7492_RS27255	COG1115	amino acid carrier protein
B7492_RS27260	COG0783	Belongs to the Dps family
B7492_RS27270	COG2318	DinB family
B7492_RS27275	COG1611	Belongs to the LOG family
B7492_RS27285	COG1528	Iron-storage protein
B7492_RS27290	COG2311	Membrane
B7492_RS27300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS27305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS27310	COG1115	amino acid carrier protein
B7492_RS27315	COG2910	NAD(P)H-binding
B7492_RS27345	COG0656	L-ascorbic acid biosynthetic process
B7492_RS27350	COG2814	Major facilitator Superfamily
B7492_RS27355	COG1733	regulation of RNA biosynthetic process
B7492_RS27365	COG1252	NADH dehydrogenase
B7492_RS27400	COG0840	transmembrane signaling receptor activity
B7492_RS27400	COG3290	protein histidine kinase activity
B7492_RS27435	COG0488	(ABC) transporter
B7492_RS27440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS27455	COG1335	isochorismatase
B7492_RS27465	COG1522	sequence-specific DNA binding
B7492_RS27470	COG1522	sequence-specific DNA binding
B7492_RS27475	COG0288	reversible hydration of carbon dioxide
B7492_RS27480	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
B7492_RS27485	COG2233	PERMEase
B7492_RS27530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B7492_RS27540	COG0557	exoribonuclease II activity
B7492_RS27545	COG1647	Serine aminopeptidase, S33
B7492_RS27550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B7492_RS27555	COG1346	cytolysis
B7492_RS27570	COG0148	phosphopyruvate hydratase activity
B7492_RS27580	COG0149	triose-phosphate isomerase activity
B7492_RS27585	COG0126	phosphoglycerate kinase activity
B7492_RS27590	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7492_RS27605	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B7492_RS27640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B7492_RS27655	COG2323	membrane
B7492_RS27670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7492_RS27675	COG1481	regulation of sporulation
B7492_RS27680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B7492_RS27685	COG1660	Displays ATPase and GTPase activities
B7492_RS27690	COG1051	belongs to the nudix hydrolase family
B7492_RS27700	COG0492	ferredoxin-NADP+ reductase activity
B7492_RS27705	COG0457	Tetratricopeptide repeat
B7492_RS27710	COG0110	maltose O-acetyltransferase activity
B7492_RS27715	COG0546	phosphoglycolate phosphatase activity
B7492_RS27720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B7492_RS27725	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B7492_RS27730	COG1950	PFAM Membrane protein of
B7492_RS27740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7492_RS27760	COG0789	Transcriptional regulator
B7492_RS27795	COG0583	DNA-binding transcription factor activity
B7492_RS27800	COG0789	Transcriptional regulator
B7492_RS27805	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7492_RS27810	COG0488	(ABC) transporter
B7492_RS27820	COG1132	(ABC) transporter
B7492_RS27825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7492_RS27830	COG0793	Belongs to the peptidase S41A family
B7492_RS27830	COG3409	Peptidoglycan-binding domain 1 protein
B7492_RS27835	COG2177	Part of the ABC transporter FtsEX involved in
B7492_RS27840	COG2884	Cell division ATP-binding protein ftsE
B7492_RS27855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B7492_RS27885	COG1278	Cold shock
B7492_RS27890	COG1040	competence protein
B7492_RS27895	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B7492_RS27900	COG1388	LysM domain
B7492_RS27900	COG0791	NLP P60 protein
B7492_RS27905	COG1733	regulation of RNA biosynthetic process
B7492_RS27910	COG1307	EDD domain protein, DegV family
B7492_RS27915	COG1739	Uncharacterized protein family UPF0029
B7492_RS27920	COG1316	TRANSCRIPTIONal
B7492_RS27925	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B7492_RS27930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B7492_RS27935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7492_RS27945	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
B7492_RS27945	COG3933	PFAM sigma-54 factor interaction domain-containing protein
B7492_RS27965	COG1486	melibiose metabolic process
B7492_RS27970	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7492_RS27975	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7492_RS27980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7492_RS28005	COG1447	Phosphotransferase system cellobiose-specific component IIA
B7492_RS28015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B7492_RS28020	COG1301	dicarboxylic acid transport
B7492_RS28040	COG1511	domain protein
B7492_RS28045	COG0583	DNA-binding transcription factor activity
B7492_RS28050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
B7492_RS28055	COG1271	oxidase subunit
B7492_RS28060	COG1294	oxidase, subunit
B7492_RS28065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B7492_RS28070	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B7492_RS28075	COG1620	l-lactate permease
B7492_RS28085	COG2389	metal-binding protein
B7492_RS28100	COG1368	sulfuric ester hydrolase activity
B7492_RS28110	COG0791	NLP P60 protein
B7492_RS28110	COG1388	LysM domain
B7492_RS28115	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B7492_RS28125	COG1215	transferase activity, transferring glycosyl groups
B7492_RS28130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7492_RS28140	COG1388	LysM domain
B7492_RS28140	COG3584	3D domain protein
B7492_RS28165	COG4715	Zinc finger, swim domain protein
B7492_RS28170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B7492_RS28210	COG0577	efflux transmembrane transporter activity
B7492_RS28215	COG1136	(ABC) transporter
B7492_RS28240	COG3850	Histidine kinase
B7492_RS28240	COG5002	protein histidine kinase activity
B7492_RS28245	COG0745	RESPONSE REGULATOR receiver
B7492_RS28250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7492_RS28265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B7492_RS28275	COG1091	dTDP-4-dehydrorhamnose reductase activity
B7492_RS28290	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B7492_RS28325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7492_RS28330	COG4464	protein tyrosine phosphatase activity
B7492_RS28335	COG0489	protein tyrosine kinase activity
B7492_RS28340	COG3944	biosynthesis protein
B7492_RS28345	COG0489	protein tyrosine kinase activity
B7492_RS28360	COG1609	Transcriptional regulator
B7492_RS28370	COG0739	heme binding
B7492_RS28385	COG3279	Response regulator of the LytR AlgR family
B7492_RS28390	COG2385	sporulation resulting in formation of a cellular spore
B7492_RS28405	COG4836	Membrane
B7492_RS28410	COG1007	ATP synthesis coupled electron transport
B7492_RS28415	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7492_RS28420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7492_RS28425	COG0713	ATP synthesis coupled electron transport
B7492_RS28430	COG0839	Belongs to the complex I subunit 6 family
B7492_RS28440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B7492_RS28445	COG0649	NAD binding
B7492_RS28450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7492_RS28455	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7492_RS28460	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7492_RS28465	COG3300	MHYT domain
B7492_RS28465	COG5001	Diguanylate cyclase
B7492_RS28480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B7492_RS28485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B7492_RS28490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B7492_RS28495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
B7492_RS28500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B7492_RS28505	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B7492_RS28515	COG0356	it plays a direct role in the translocation of protons across the membrane
B7492_RS28540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B7492_RS28550	COG0698	ribose 5-phosphate isomerase
B7492_RS28560	COG2190	(PTS) system
B7492_RS28565	COG2259	Doxx family
B7492_RS28570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7492_RS28580	COG1971	Probably functions as a manganese efflux pump
B7492_RS28585	COG0009	L-threonylcarbamoyladenylate synthase
B7492_RS28600	COG2890	protein-(glutamine-N5) methyltransferase activity
B7492_RS28605	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B7492_RS28610	COG1435	thymidine kinase activity
B7492_RS28625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B7492_RS28630	COG1494	fructose-1,6-bisphosphatase
B7492_RS28650	COG4821	SIS domain
B7492_RS28655	COG0504	CTP synthase activity
B7492_RS28660	COG3343	RNA polymerase activity
B7492_RS28670	COG1960	acyl-CoA dehydrogenase activity
B7492_RS28675	COG1960	acyl-CoA dehydrogenase activity
B7492_RS28680	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7492_RS28685	COG0183	Belongs to the thiolase family
B7492_RS28690	COG2181	nitrate reductase activity
B7492_RS28690	COG0247	lactate metabolic process
B7492_RS28695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7492_RS28700	COG4294	response to UV
B7492_RS28705	COG3300	MHYT domain
B7492_RS28705	COG5001	Diguanylate cyclase
B7492_RS28720	COG3227	Zinc metalloprotease (Elastase)
B7492_RS28725	COG2197	response regulator
B7492_RS28730	COG4585	Histidine kinase
B7492_RS28735	COG0842	Transport permease protein
B7492_RS28740	COG1131	(ABC) transporter
B7492_RS28745	COG0024	Methionine aminopeptidase
B7492_RS28755	COG2234	aminopeptidase activity
B7492_RS28775	COG4506	Protein conserved in bacteria
B7492_RS28780	COG1619	proteins homologs of microcin C7 resistance protein MccF
B7492_RS28800	COG0010	Belongs to the arginase family
B7492_RS28805	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B7492_RS28810	COG2814	Major facilitator Superfamily
B7492_RS28815	COG0789	Transcriptional regulator
B7492_RS28820	COG0584	glycerophosphoryl diester phosphodiesterase
B7492_RS28825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7492_RS28835	COG1994	Peptidase M50
B7492_RS28845	COG1078	dGTPase activity
B7492_RS28850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B7492_RS28855	COG1120	ATPase activity
B7492_RS28860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS28865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7492_RS28870	COG4844	belongs to the
B7492_RS28885	COG0280	phosphate acetyltransferase
B7492_RS28890	COG3253	May function as heme-dependent peroxidase
B7492_RS28900	COG3773	Cell wall hydrolase
B7492_RS28910	COG2363	Small membrane protein
B7492_RS28925	COG2233	PERMEase
B7492_RS28930	COG0561	phosphatase activity
B7492_RS28935	COG2814	Major facilitator Superfamily
B7492_RS28940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
B7492_RS28945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B7492_RS28950	COG1131	(ABC) transporter
B7492_RS28955	COG2755	lipolytic protein G-D-S-L family
B7492_RS28960	COG1609	Transcriptional regulator
B7492_RS28975	COG0460	homoserine dehydrogenase
B7492_RS28980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B7492_RS28985	COG2873	o-acetylhomoserine
B7492_RS29000	COG1011	Hydrolase
B7492_RS29005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7492_RS29015	COG2197	response regulator
B7492_RS29020	COG4585	Histidine kinase
B7492_RS29020	COG2203	Gaf domain
B7492_RS29025	COG0351	phosphomethylpyrimidine kinase
B7492_RS29035	COG2879	small protein
B7492_RS29040	COG1966	Carbon starvation protein
B7492_RS29045	COG3279	Response regulator of the LytR AlgR family
B7492_RS29050	COG0477	Major facilitator Superfamily
B7492_RS29075	COG0840	transmembrane signaling receptor activity
B7492_RS29085	COG1607	acyl-coa hydrolase
B7492_RS29090	COG1216	Glycosyl transferase, family 2
B7492_RS29105	COG1216	Glycosyl transferase, family 2
B7492_RS29115	COG0488	(ABC) transporter
B7492_RS29120	COG1309	transcriptional regulator
B7492_RS29125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7492_RS29130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7492_RS29130	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B7492_RS29135	COG0628	permease
B7492_RS29145	COG1380	Effector of murein hydrolase LrgA
B7492_RS29150	COG3279	Response regulator of the LytR AlgR family
B7492_RS29155	COG3275	phosphorelay sensor kinase activity
B7492_RS29160	COG2814	Major facilitator Superfamily
B7492_RS29165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7492_RS29170	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B7492_RS29180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7492_RS29230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7492_RS29235	COG1272	protein, Hemolysin III
B7492_RS29265	COG1164	Oligoendopeptidase f
B7492_RS29275	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B7492_RS29285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7492_RS29290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B7492_RS29295	COG4853	Protein conserved in bacteria
B7492_RS29305	COG5002	protein histidine kinase activity
B7492_RS29310	COG0745	RESPONSE REGULATOR receiver
B7492_RS29340	COG0305	Participates in initiation and elongation during chromosome replication
B7492_RS29345	COG0359	binds to the 23S rRNA
B7492_RS29350	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B7492_RS29355	COG4241	membrane
B7492_RS29365	COG0629	single-stranded DNA binding
B7492_RS29370	COG0360	Binds together with S18 to 16S ribosomal RNA
B7492_RS29375	COG0012	GTP binding
B7492_RS29380	COG4481	Protein conserved in bacteria
B7492_RS29385	COG0668	transmembrane transport
B7492_RS29395	COG1475	DNA binding
B7492_RS29400	COG1192	Involved in chromosome partitioning
B7492_RS29405	COG1475	DNA binding
B7492_RS29410	COG0357	Ribosomal RNA small subunit methyltransferase G
B7492_RS29415	COG0445	tRNA wobble uridine modification
B7492_RS29420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B7492_RS29425	COG1847	R3H domain protein
B7492_RS29430	COG0706	membrane insertase activity
B7492_RS29435	COG0594	ribonuclease P activity
B7492_RS29440	COG0230	Belongs to the bacterial ribosomal protein bL34 family
B7492_RS29450	COG0582	viral genome integration into host DNA
B7492_RS29470	COG1396	sequence-specific DNA binding
B7492_RS29540	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7492_RS29560	COG1131	(ABC) transporter
B7492_RS29565	COG1725	Transcriptional regulator
B7492_RS29590	COG2801	Transposase and inactivated derivatives
B7492_RS29605	COG0789	Transcriptional regulator
B7492_RS29610	COG3620	sequence-specific DNA binding
B7492_RS29625	COG3173	Aminoglycoside phosphotransferase
B7492_RS29635	COG0024	Methionine aminopeptidase
B7492_RS29685	COG0457	Tetratricopeptide repeat
B7492_RS29710	COG1923	regulation of RNA biosynthetic process
B7492_RS29725	COG3764	Sortase (surface protein transpeptidase)
B7492_RS29780	COG0583	DNA-binding transcription factor activity
B7492_RS29785	COG2814	Major facilitator Superfamily
B7492_RS29795	COG2239	Acts as a magnesium transporter
B7492_RS29800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7492_RS29815	COG0697	spore germination
B7492_RS29915	COG4974	Belongs to the 'phage' integrase family
B7492_RS29935	COG1404	Belongs to the peptidase S8 family
B7492_RS29970	COG1404	Belongs to the peptidase S8 family
B7492_RS29995	COG2239	Acts as a magnesium transporter
B7492_RS30000	COG0772	Belongs to the SEDS family
B7492_RS30025	COG0745	RESPONSE REGULATOR receiver
B7492_RS30070	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B7492_RS30095	COG2814	Major facilitator Superfamily
B7492_RS30100	COG1846	Transcriptional regulator
B7492_RS30105	COG1846	Transcriptional regulator
B7492_RS30110	COG2124	cytochrome p450
B7492_RS30150	COG0840	transmembrane signaling receptor activity
B7492_RS30170	COG1396	sequence-specific DNA binding
B7492_RS30195	COG3344	reverse transcriptase
B7492_RS30225	COG0697	spore germination
B7492_RS30245	COG0662	Cupin 2, conserved barrel domain protein
B7492_RS30250	COG2205	protein histidine kinase activity
B7492_RS30255	COG0745	RESPONSE REGULATOR receiver
B7492_RS30260	COG0577	efflux transmembrane transporter activity
B7492_RS30265	COG1136	(ABC) transporter
B7492_RS30290	COG0814	amino acid
B7492_RS30295	COG1760	l-serine dehydratase
B7492_RS30300	COG1760	l-serine dehydratase
B7492_RS30350	COG0456	acetyltransferase
B7492_RS30365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7492_RS30375	COG0010	Belongs to the arginase family
B7492_RS30380	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
B7492_RS30385	COG0662	Cupin 2, conserved barrel domain protein
B7492_RS30390	COG1999	signal sequence binding
B7492_RS30465	COG2801	Transposase and inactivated derivatives
B7492_RS30480	COG0789	Transcriptional regulator
B7492_RS30485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7492_RS30490	COG1923	regulation of RNA biosynthetic process
B7492_RS30585	COG1923	regulation of RNA biosynthetic process
B7492_RS30615	COG1780	Probably involved in ribonucleotide reductase function
B7492_RS30655	COG0535	radical SAM domain protein
B7492_RS30660	COG2226	methyltransferase
B7492_RS30665	COG0582	viral genome integration into host DNA
B7492_RS30675	COG5444	nuclease activity
B7492_RS30685	COG0697	spore germination
B7492_RS30690	COG1802	Transcriptional regulator
B7492_RS30805	COG0756	dUTP diphosphatase activity
B7492_RS30900	COG3344	reverse transcriptase
B7492_RS30920	COG2311	Membrane
B7492_RS30990	COG3344	reverse transcriptase
B7492_RS30995	COG1674	ftsk spoiiie
B7492_RS30995	COG4980	gas vesicle protein
B7492_RS31000	COG1476	TRANSCRIPTIONal
B7492_RS31025	COG0675	Transposase, IS605 OrfB family
B7492_RS31030	COG2169	Transcriptional regulator
B7492_RS31035	COG0673	inositol 2-dehydrogenase activity
B7492_RS31040	COG0673	inositol 2-dehydrogenase activity
B7492_RS31195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7492_RS31225	COG0741	lytic transglycosylase activity
B7492_RS31235	COG0577	efflux transmembrane transporter activity
B7492_RS31240	COG1136	(ABC) transporter
B7492_RS31280	COG0456	acetyltransferase
B7492_RS31290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7492_RS31295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7492_RS31300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B7492_RS31315	COG0363	glucosamine-6-phosphate deaminase activity
B7492_RS31325	COG2234	aminopeptidase activity
B7492_RS31330	COG2814	Major facilitator Superfamily
B7492_RS31340	COG1404	Belongs to the peptidase S8 family
B7492_RS31435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7492_RS31440	COG5002	protein histidine kinase activity
B7492_RS31445	COG0745	RESPONSE REGULATOR receiver
B7492_RS31490	COG3397	chitin binding
B7492_RS31505	COG0542	response to heat
B7492_RS31620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7492_RS31675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B7492_RS31705	COG1136	(ABC) transporter
B7492_RS31710	COG0577	efflux transmembrane transporter activity
B7492_RS31955	COG3209	COG3209 Rhs family protein
B7492_RS31990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7492_RS32000	COG0823	Involved in the tonB-independent uptake of proteins
B7492_RS32010	COG0697	spore germination
B7492_RS32030	COG4644	lycopene metabolic process
B7492_RS32170	COG2002	toxin-antitoxin pair type II binding
B7492_RS32430	COG1192	Involved in chromosome partitioning
B7492_RS32465	COG4166	transmembrane transport
B7492_RS32475	COG0457	Tetratricopeptide repeat
B7492_RS32510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7492_RS32550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7492_RS32560	COG1063	alcohol dehydrogenase
B7492_RS32585	COG2133	pyrroloquinoline quinone binding
B7492_RS32585	COG5183	chlorophyll binding
B7492_RS32595	COG0577	efflux transmembrane transporter activity
B7492_RS32595	COG1136	(ABC) transporter
B7492_RS32630	COG4974	Belongs to the 'phage' integrase family
B7492_RS32685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7492_RS32780	COG0791	NLP P60 protein
B7492_RS32780	COG0741	lytic transglycosylase activity
B7492_RS32875	COG4644	lycopene metabolic process
B7492_RS32900	COG0582	viral genome integration into host DNA
B7492_RS32920	COG2197	response regulator
B7492_RS32970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7492_RS33135	COG3883	PFAM NLP P60 protein
B7492_RS33135	COG0791	NLP P60 protein
B7492_RS33205	COG2002	toxin-antitoxin pair type II binding
B7492_RS33210	COG3209	COG3209 Rhs family protein
B7492_RS33220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B7492_RS33290	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7492_RS33305	COG1395	domain, Protein
B7492_RS33335	COG1192	Involved in chromosome partitioning
B7492_RS33400	COG0270	DNA (cytosine-5-)-methyltransferase activity
B7492_RS33425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7492_RS33450	COG0457	Tetratricopeptide repeat
B7492_RS33515	COG0551	DNA topoisomerase type I activity
B7492_RS33515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7492_RS33595	COG0739	heme binding
B7492_RS33655	COG0457	Tetratricopeptide repeat
B7492_RS33795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B7492_RS33815	COG3331	DNA recombination
B7492_RS33850	COG3344	reverse transcriptase
B7492_RS33860	COG5484	DNA packaging
B7492_RS33865	COG1783	phage Terminase large subunit
B7492_RS33880	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B7492_RS33885	COG4653	Phage capsid family
B7492_RS33950	COG4644	lycopene metabolic process
B7492_RS34020	COG3620	sequence-specific DNA binding
B7492_RS34155	COG5484	DNA packaging
B7492_RS34275	COG0756	dUTP diphosphatase activity
B7492_RS34390	COG1278	Cold shock
B7492_RS34420	COG0582	viral genome integration into host DNA