locus-tag	class	description
EXW36_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW36_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW36_RS00015	COG2501	S4 domain
EXW36_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW36_RS00025	COG0187	DNA topoisomerase II activity
EXW36_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW36_RS00065	COG0516	GMP reductase activity
EXW36_RS00065	COG0517	IMP dehydrogenase activity
EXW36_RS00070	COG1686	Belongs to the peptidase S11 family
EXW36_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW36_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW36_RS00100	COG1428	Deoxynucleoside kinase
EXW36_RS00105	COG1428	Deoxynucleoside kinase
EXW36_RS00110	COG1335	isochorismatase
EXW36_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW36_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW36_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW36_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW36_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW36_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW36_RS00190	COG0470	DNA polymerase III
EXW36_RS00195	COG1774	PSP1 C-terminal conserved region
EXW36_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW36_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW36_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW36_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW36_RS00230	COG0084	hydrolase, TatD family'
EXW36_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW36_RS00250	COG4466	Protein conserved in bacteria
EXW36_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW36_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW36_RS00270	COG0251	oxidation-reduction process
EXW36_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW36_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW36_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW36_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW36_RS00310	COG2244	polysaccharide biosynthetic process
EXW36_RS00315	COG3956	TIGRFAM MazG family protein
EXW36_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW36_RS00340	COG1098	S1 RNA binding domain
EXW36_RS00355	COG2208	phosphoserine phosphatase activity
EXW36_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW36_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW36_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW36_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW36_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW36_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW36_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW36_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW36_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW36_RS00420	COG1396	sequence-specific DNA binding
EXW36_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW36_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW36_RS00515	COG3880	PFAM UvrB UvrC protein
EXW36_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW36_RS00525	COG0542	response to heat
EXW36_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW36_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW36_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW36_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW36_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW36_RS00560	COG1045	serine acetyltransferase
EXW36_RS00565	COG0215	cysteine-tRNA ligase activity
EXW36_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW36_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW36_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW36_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW36_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW36_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW36_RS00610	COG0081	regulation of translation
EXW36_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW36_RS00620	COG0222	ribosome binding
EXW36_RS00625	COG2813	Specifically methylates the guanine in position
EXW36_RS00630	COG0085	RNA polymerase activity
EXW36_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW36_RS00640	COG1358	cellular component organization or biogenesis
EXW36_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW36_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW36_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW36_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW36_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW36_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW36_RS00680	COG0089	rRNA binding
EXW36_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW36_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW36_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW36_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW36_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW36_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW36_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW36_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW36_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW36_RS00760	COG1841	ribosomal large subunit assembly
EXW36_RS00765	COG0200	Binds to the 23S rRNA
EXW36_RS00770	COG0201	protein transport
EXW36_RS00775	COG0563	adenylate kinase activity
EXW36_RS00780	COG0024	Methionine aminopeptidase
EXW36_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW36_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW36_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW36_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW36_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW36_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW36_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS00855	COG0489	protein tyrosine kinase activity
EXW36_RS00865	COG2194	sulfuric ester hydrolase activity
EXW36_RS00870	COG0726	polysaccharide deacetylase
EXW36_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW36_RS00955	COG4856	YbbR-like protein
EXW36_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW36_RS00975	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_RS00975	COG1506	peptidase
EXW36_RS00975	COG4946	Tricorn protease homolog
EXW36_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS00995	COG2011	ABC-type metal ion transport system permease component
EXW36_RS01005	COG1464	Belongs to the NlpA lipoprotein family
EXW36_RS01010	COG0604	alcohol dehydrogenase
EXW36_RS01020	COG0277	FAD linked oxidase domain protein
EXW36_RS01025	COG2271	Major facilitator Superfamily
EXW36_RS01035	COG2814	Major facilitator Superfamily
EXW36_RS01050	COG0601	transmembrane transport
EXW36_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_RS01060	COG0444	Belongs to the ABC transporter superfamily
EXW36_RS01065	COG4608	Belongs to the ABC transporter superfamily
EXW36_RS01070	COG4166	transmembrane transport
EXW36_RS01080	COG2207	Transcriptional regulator
EXW36_RS01095	COG4166	transmembrane transport
EXW36_RS01100	COG4166	transmembrane transport
EXW36_RS01105	COG0656	L-ascorbic acid biosynthetic process
EXW36_RS01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_RS01125	COG4149	molybdate abc transporter
EXW36_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW36_RS01135	COG1910	domain protein
EXW36_RS01150	COG0697	spore germination
EXW36_RS01165	COG0204	Acyl-transferase
EXW36_RS01175	COG1609	Transcriptional regulator
EXW36_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS01200	COG5298	Protein conserved in bacteria
EXW36_RS01220	COG0488	(ABC) transporter
EXW36_RS01225	COG4585	Histidine kinase
EXW36_RS01230	COG2197	response regulator
EXW36_RS01235	COG1131	(ABC) transporter
EXW36_RS01240	COG0842	Transport permease protein
EXW36_RS01240	COG1511	domain protein
EXW36_RS01245	COG0842	Transport permease protein
EXW36_RS01255	COG0747	negative chemotaxis
EXW36_RS01265	COG0601	transmembrane transport
EXW36_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_RS01275	COG0444	Belongs to the ABC transporter superfamily
EXW36_RS01280	COG4608	Belongs to the ABC transporter superfamily
EXW36_RS01285	COG0561	phosphatase activity
EXW36_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW36_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW36_RS01325	COG0531	amino acid
EXW36_RS01330	COG2814	Major facilitator Superfamily
EXW36_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW36_RS01350	COG4294	response to UV
EXW36_RS01355	COG0705	Rhomboid family
EXW36_RS01360	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW36_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW36_RS01375	COG0864	Transcriptional regulator
EXW36_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW36_RS01385	COG2183	response to ionizing radiation
EXW36_RS01485	COG0802	atpase or kinase
EXW36_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW36_RS01495	COG0456	acetyltransferase
EXW36_RS01505	COG0488	(ABC) transporter
EXW36_RS01510	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW36_RS01520	COG1266	CAAX protease self-immunity
EXW36_RS01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW36_RS01530	COG0459	protein refolding
EXW36_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
EXW36_RS01535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW36_RS01540	COG2252	PERMEase
EXW36_RS01550	COG5002	protein histidine kinase activity
EXW36_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW36_RS01630	COG2205	protein histidine kinase activity
EXW36_RS01635	COG0745	RESPONSE REGULATOR receiver
EXW36_RS01655	COG0697	spore germination
EXW36_RS01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW36_RS01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW36_RS01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW36_RS01695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW36_RS01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW36_RS01705	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW36_RS01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW36_RS01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW36_RS01720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW36_RS01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW36_RS01730	COG0138	bifunctional purine biosynthesis protein purh
EXW36_RS01735	COG0151	Belongs to the GarS family
EXW36_RS01755	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW36_RS01760	COG0210	DNA helicase
EXW36_RS01765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW36_RS01770	COG4851	CamS sex pheromone cAM373 precursor
EXW36_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS01785	COG1335	isochorismatase
EXW36_RS01795	COG2011	ABC-type metal ion transport system permease component
EXW36_RS01800	COG1464	Belongs to the NlpA lipoprotein family
EXW36_RS01815	COG0003	Pfam Anion-transporting ATPase
EXW36_RS01820	COG1846	Transcriptional regulator
EXW36_RS01825	COG4682	membrane
EXW36_RS01835	COG0154	amidase activity
EXW36_RS01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW36_RS01845	COG1597	lipid kinase activity
EXW36_RS01850	COG0546	phosphoglycolate phosphatase activity
EXW36_RS01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS01870	COG2076	Multidrug Resistance protein
EXW36_RS01875	COG2309	aminopeptidase activity
EXW36_RS01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW36_RS01905	COG5002	protein histidine kinase activity
EXW36_RS01910	COG4807	Protein conserved in bacteria
EXW36_RS01935	COG1757	Na H antiporter
EXW36_RS01940	COG1473	amidohydrolase
EXW36_RS01955	COG0450	alkyl hydroperoxide reductase
EXW36_RS01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW36_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS01990	COG0492	ferredoxin-NADP+ reductase activity
EXW36_RS02000	COG0166	Belongs to the GPI family
EXW36_RS02025	COG5002	protein histidine kinase activity
EXW36_RS02045	COG3541	Predicted nucleotidyltransferase
EXW36_RS02050	COG2814	Major facilitator Superfamily
EXW36_RS02055	COG0723	plastoquinol--plastocyanin reductase activity
EXW36_RS02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_RS02065	COG0765	amino acid transport
EXW36_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS02080	COG0840	transmembrane signaling receptor activity
EXW36_RS02085	COG0277	FAD linked oxidase domain protein
EXW36_RS02090	COG0366	Alpha amylase catalytic
EXW36_RS02095	COG1263	PTS System
EXW36_RS02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS02095	COG2190	(PTS) system
EXW36_RS02115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW36_RS02120	COG0352	thiamine-phosphate diphosphorylase activity
EXW36_RS02125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW36_RS02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_RS02145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_RS02150	COG1116	anion transmembrane transporter activity
EXW36_RS02155	COG0488	(ABC) transporter
EXW36_RS02200	COG2270	Major facilitator Superfamily
EXW36_RS02230	COG2310	stress, protein
EXW36_RS02235	COG2310	stress, protein
EXW36_RS02240	COG2310	stress, protein
EXW36_RS02245	COG0861	Integral membrane protein TerC family
EXW36_RS02255	COG3853	Toxic anion resistance protein (TelA)
EXW36_RS02265	COG4840	Belongs to the UPF0435 family
EXW36_RS02270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW36_RS02280	COG1295	ribonuclease BN
EXW36_RS02285	COG2217	Heavy metal translocating P-type atpase
EXW36_RS02290	COG0697	spore germination
EXW36_RS02310	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS02325	COG3871	stress protein (general stress protein 26)
EXW36_RS02330	COG0387	Pfam Sodium calcium exchanger
EXW36_RS02340	COG0535	radical SAM domain protein
EXW36_RS02360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW36_RS02380	COG3829	transcription factor binding
EXW36_RS02390	COG0833	amino acid
EXW36_RS02395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_RS02415	COG2066	Belongs to the glutaminase family
EXW36_RS02420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS02420	COG1263	PTS System
EXW36_RS02425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_RS02440	COG1216	Glycosyl transferase, family 2
EXW36_RS02450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW36_RS02450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_RS02455	COG0463	Glycosyl transferase, family 2
EXW36_RS02470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW36_RS02475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW36_RS02490	COG1228	amidohydrolase
EXW36_RS02495	COG1090	epimerase
EXW36_RS02500	COG2137	regulation of response to DNA damage stimulus
EXW36_RS02525	COG1988	membrane-bound metal-dependent
EXW36_RS02530	COG1194	a g-specific adenine glycosylase
EXW36_RS02550	COG3557	Belongs to the UPF0374 family
EXW36_RS02555	COG1132	(ABC) transporter
EXW36_RS02560	COG4129	membrane
EXW36_RS02565	COG0070	glutamate synthase
EXW36_RS02565	COG0069	glutamate synthase activity
EXW36_RS02565	COG0067	glutamate synthase
EXW36_RS02570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW36_RS02575	COG4555	ABC transporter
EXW36_RS02595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW36_RS02600	COG0735	belongs to the Fur family
EXW36_RS02705	COG4974	Belongs to the 'phage' integrase family
EXW36_RS02785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW36_RS02790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW36_RS02810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW36_RS02820	COG2766	serine protein kinase
EXW36_RS02825	COG2718	Belongs to the UPF0229 family
EXW36_RS02840	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW36_RS02845	COG2268	Band 7 protein
EXW36_RS02855	COG3290	protein histidine kinase activity
EXW36_RS02860	COG4565	transcriptional regulatory protein
EXW36_RS02865	COG2851	Citrate transporter
EXW36_RS02890	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW36_RS02895	COG3842	ATPase activity
EXW36_RS02900	COG1175	transmembrane transport
EXW36_RS02905	COG0395	ABC-type sugar transport system, permease component
EXW36_RS02915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW36_RS02920	COG0745	RESPONSE REGULATOR receiver
EXW36_RS02925	COG5002	protein histidine kinase activity
EXW36_RS02935	COG4990	cell redox homeostasis
EXW36_RS02945	COG3290	protein histidine kinase activity
EXW36_RS02950	COG4565	transcriptional regulatory protein
EXW36_RS02955	COG3493	citrate carrier protein
EXW36_RS02960	COG0281	malic enzyme
EXW36_RS02970	COG0697	spore germination
EXW36_RS02975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS02985	COG5002	protein histidine kinase activity
EXW36_RS02990	COG0745	RESPONSE REGULATOR receiver
EXW36_RS02995	COG0456	acetyltransferase
EXW36_RS03000	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW36_RS03005	COG3383	formate dehydrogenase (NAD+) activity
EXW36_RS03010	COG2427	Protein of unknown function (DUF1641)
EXW36_RS03025	COG0531	amino acid
EXW36_RS03035	COG0640	Transcriptional regulator
EXW36_RS03040	COG2217	Heavy metal translocating P-type atpase
EXW36_RS03045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW36_RS03060	COG3227	Zinc metalloprotease (Elastase)
EXW36_RS03080	COG2720	vancomycin resistance protein
EXW36_RS03085	COG1316	TRANSCRIPTIONal
EXW36_RS03090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS03095	COG0346	lactoylglutathione lyase activity
EXW36_RS03100	COG1253	flavin adenine dinucleotide binding
EXW36_RS03105	COG1027	Aspartate ammonia-lyase
EXW36_RS03110	COG1620	l-lactate permease
EXW36_RS03115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS03130	COG3104	oligopeptide transport
EXW36_RS03135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS03140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS03145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS03160	COG0156	8-amino-7-oxononanoate synthase activity
EXW36_RS03165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_RS03175	COG4548	von Willebrand factor, type A
EXW36_RS03180	COG0714	Associated with various cellular activities
EXW36_RS03200	COG0531	amino acid
EXW36_RS03205	COG2188	Transcriptional regulator
EXW36_RS03210	COG1263	PTS System
EXW36_RS03210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS03215	COG0366	Alpha amylase catalytic
EXW36_RS03230	COG0697	spore germination
EXW36_RS03235	COG4585	Histidine kinase
EXW36_RS03240	COG2197	response regulator
EXW36_RS03245	COG1404	Belongs to the peptidase S8 family
EXW36_RS03260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_RS03265	COG1115	amino acid carrier protein
EXW36_RS03270	COG1126	abc transporter atp-binding protein
EXW36_RS03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS03280	COG0765	amino acid transport
EXW36_RS03285	COG0765	amino acid transport
EXW36_RS03290	COG0833	amino acid
EXW36_RS03305	COG2378	regulation of single-species biofilm formation
EXW36_RS03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW36_RS03315	COG5002	protein histidine kinase activity
EXW36_RS03330	COG0659	secondary active sulfate transmembrane transporter activity
EXW36_RS03345	COG0747	negative chemotaxis
EXW36_RS03355	COG0601	transmembrane transport
EXW36_RS03360	COG4608	Belongs to the ABC transporter superfamily
EXW36_RS03370	COG2271	Major facilitator Superfamily
EXW36_RS03375	COG1846	Transcriptional regulator
EXW36_RS03380	COG0477	Major facilitator Superfamily
EXW36_RS03385	COG1609	Transcriptional regulator
EXW36_RS03390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW36_RS03395	COG1869	D-ribose catabolic process
EXW36_RS03405	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW36_RS03410	COG1879	ABC-type sugar transport system periplasmic component
EXW36_RS03440	COG1063	alcohol dehydrogenase
EXW36_RS03455	COG3568	Endonuclease Exonuclease Phosphatase
EXW36_RS03485	COG0840	transmembrane signaling receptor activity
EXW36_RS03490	COG3584	3D domain protein
EXW36_RS03490	COG3583	domain protein
EXW36_RS03495	COG1476	TRANSCRIPTIONal
EXW36_RS03515	COG3104	oligopeptide transport
EXW36_RS03520	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS03535	COG1113	amino acid transport
EXW36_RS03540	COG2252	PERMEase
EXW36_RS03565	COG0475	glutathione-regulated potassium exporter activity
EXW36_RS03565	COG0569	domain protein
EXW36_RS03575	COG1845	cytochrome c oxidase, subunit III
EXW36_RS03580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW36_RS03590	COG0833	amino acid
EXW36_RS03595	COG4990	cell redox homeostasis
EXW36_RS03610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_RS03615	COG0697	spore germination
EXW36_RS03620	COG0531	amino acid
EXW36_RS03630	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW36_RS03635	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW36_RS03645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW36_RS03650	COG0573	inorganic phosphate transmembrane transporter activity
EXW36_RS03655	COG0581	inorganic phosphate transmembrane transporter activity
EXW36_RS03665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW36_RS03785	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW36_RS03800	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS03800	COG4991	sh3 domain protein
EXW36_RS03800	COG3103	Sh3 type 3 domain protein
EXW36_RS03805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW36_RS03810	COG1116	anion transmembrane transporter activity
EXW36_RS03815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_RS03820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_RS03825	COG0352	thiamine-phosphate diphosphorylase activity
EXW36_RS03830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_RS03835	COG2104	thiamine diphosphate biosynthetic process
EXW36_RS03840	COG2022	thiamine diphosphate biosynthetic process
EXW36_RS03845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_RS03850	COG0351	phosphomethylpyrimidine kinase
EXW36_RS03875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW36_RS03880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW36_RS03885	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW36_RS03890	COG2205	protein histidine kinase activity
EXW36_RS03895	COG2814	Major facilitator Superfamily
EXW36_RS03900	COG1846	Transcriptional regulator
EXW36_RS03920	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW36_RS03925	COG1129	ABC transporter
EXW36_RS03930	COG1879	ABC-type sugar transport system periplasmic component
EXW36_RS03935	COG2252	PERMEase
EXW36_RS03940	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS03955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW36_RS03960	COG1621	beta-fructofuranosidase activity
EXW36_RS03965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS03965	COG1263	PTS System
EXW36_RS03970	COG1609	Transcriptional regulator
EXW36_RS04020	COG0778	Nitroreductase
EXW36_RS04025	COG2719	SpoVR family
EXW36_RS04050	COG1937	Protein conserved in bacteria
EXW36_RS04055	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_RS04055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS04060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS04065	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_RS04070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS04070	COG0425	Belongs to the sulfur carrier protein TusA family
EXW36_RS04075	COG2210	Belongs to the sulfur carrier protein TusA family
EXW36_RS04080	COG0730	response to heat
EXW36_RS04090	COG1316	TRANSCRIPTIONal
EXW36_RS04095	COG0604	alcohol dehydrogenase
EXW36_RS04100	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW36_RS04105	COG0604	alcohol dehydrogenase
EXW36_RS04110	COG2814	Major facilitator Superfamily
EXW36_RS04120	COG3711	transcriptional antiterminator
EXW36_RS04120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_RS04125	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_RS04130	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_RS04155	COG1388	LysM domain
EXW36_RS04155	COG3584	3D domain protein
EXW36_RS04160	COG0577	efflux transmembrane transporter activity
EXW36_RS04165	COG1136	(ABC) transporter
EXW36_RS04175	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW36_RS04190	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS04195	COG3546	catalase activity
EXW36_RS04225	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS04255	COG0531	amino acid
EXW36_RS04270	COG1737	Transcriptional regulator
EXW36_RS04275	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW36_RS04280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS04280	COG1263	PTS System
EXW36_RS04290	COG2259	Doxx family
EXW36_RS04310	COG0697	spore germination
EXW36_RS04315	COG1522	sequence-specific DNA binding
EXW36_RS04325	COG0300	oxidoreductase activity
EXW36_RS04340	COG2076	Multidrug Resistance protein
EXW36_RS04345	COG1309	transcriptional regulator
EXW36_RS04350	COG2814	Major facilitator Superfamily
EXW36_RS04355	COG1733	regulation of RNA biosynthetic process
EXW36_RS04365	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_RS04375	COG4533	DNA binding
EXW36_RS04380	COG2211	Major facilitator Superfamily
EXW36_RS04395	COG0531	amino acid
EXW36_RS04400	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS04405	COG1132	(ABC) transporter
EXW36_RS04410	COG1132	(ABC) transporter
EXW36_RS04415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS04420	COG0765	amino acid transport
EXW36_RS04425	COG1126	abc transporter atp-binding protein
EXW36_RS04440	COG0189	ligase activity
EXW36_RS04450	COG4399	Belongs to the UPF0754 family
EXW36_RS04455	COG3679	Belongs to the UPF0342 family
EXW36_RS04470	COG0028	Belongs to the TPP enzyme family
EXW36_RS04475	COG3527	Alpha-acetolactate decarboxylase
EXW36_RS04480	COG0463	Glycosyl transferase, family 2
EXW36_RS04485	COG1216	Glycosyl transferase, family 2
EXW36_RS04490	COG2094	Belongs to the DNA glycosylase MPG family
EXW36_RS04495	COG0561	phosphatase activity
EXW36_RS04505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW36_RS04510	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS04520	COG0659	secondary active sulfate transmembrane transporter activity
EXW36_RS04530	COG2244	polysaccharide biosynthetic process
EXW36_RS04550	COG1696	Membrane protein involved in D-alanine export
EXW36_RS04565	COG1024	Enoyl-CoA hydratase
EXW36_RS04580	COG1363	Peptidase, m42
EXW36_RS04595	COG2318	DinB family
EXW36_RS04615	COG0579	oxidoreductase
EXW36_RS04645	COG0601	transmembrane transport
EXW36_RS04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_RS04655	COG0444	Belongs to the ABC transporter superfamily
EXW36_RS04660	COG4608	Belongs to the ABC transporter superfamily
EXW36_RS04755	COG0477	Major facilitator Superfamily
EXW36_RS04760	COG3290	protein histidine kinase activity
EXW36_RS04765	COG4565	transcriptional regulatory protein
EXW36_RS04770	COG3181	Tripartite tricarboxylate transporter family receptor
EXW36_RS04795	COG0789	Transcriptional regulator
EXW36_RS04795	COG4978	Transcriptional regulator
EXW36_RS04810	COG0305	Participates in initiation and elongation during chromosome replication
EXW36_RS04840	COG0477	Major facilitator Superfamily
EXW36_RS04925	COG2814	Major facilitator Superfamily
EXW36_RS04930	COG0640	Transcriptional regulator
EXW36_RS04950	COG2376	Dihydroxyacetone kinase
EXW36_RS04960	COG2376	Dihydroxyacetone kinase
EXW36_RS04975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_RS05015	COG0076	glutamate decarboxylase activity
EXW36_RS05040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS05045	COG1278	Cold shock
EXW36_RS05055	COG3266	domain, Protein
EXW36_RS05055	COG4932	domain protein
EXW36_RS05055	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW36_RS05065	COG2409	Drug exporters of the RND superfamily
EXW36_RS05090	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS05090	COG1525	nuclease
EXW36_RS05090	COG4085	toxin activity
EXW36_RS05115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW36_RS05120	COG4974	Belongs to the 'phage' integrase family
EXW36_RS05125	COG2814	Major facilitator Superfamily
EXW36_RS05130	COG0583	DNA-binding transcription factor activity
EXW36_RS05150	COG0825	malonyl-CoA metabolic process
EXW36_RS05170	COG3237	CsbD-like
EXW36_RS05190	COG2172	sigma factor antagonist activity
EXW36_RS05195	COG1191	sigma factor activity
EXW36_RS05205	COG2208	phosphoserine phosphatase activity
EXW36_RS05210	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW36_RS05215	COG5002	protein histidine kinase activity
EXW36_RS05215	COG2205	protein histidine kinase activity
EXW36_RS05215	COG0784	Response regulator, receiver
EXW36_RS05260	COG2807	transmembrane transport
EXW36_RS05265	COG2186	Transcriptional regulator
EXW36_RS05270	COG4585	Histidine kinase
EXW36_RS05275	COG2197	response regulator
EXW36_RS05305	COG0420	3'-5' exonuclease activity
EXW36_RS05310	COG4717	serine-type aminopeptidase activity
EXW36_RS05315	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW36_RS05325	COG0346	lactoylglutathione lyase activity
EXW36_RS05340	COG2267	carboxylic ester hydrolase activity
EXW36_RS05355	COG3620	sequence-specific DNA binding
EXW36_RS05360	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW36_RS05365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW36_RS05370	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW36_RS05375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW36_RS05380	COG1595	DNA-templated transcription, initiation
EXW36_RS05395	COG3973	AAA domain
EXW36_RS05400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_RS05415	COG1846	Transcriptional regulator
EXW36_RS05425	COG0537	adenosine 5'-monophosphoramidase activity
EXW36_RS05430	COG1131	(ABC) transporter
EXW36_RS05435	COG4473	ABC transporter
EXW36_RS05450	COG0247	lactate metabolic process
EXW36_RS05455	COG1139	Iron-sulfur cluster binding protein
EXW36_RS05460	COG1556	Lactate utilization protein
EXW36_RS05480	COG3402	PFAM membrane-flanked domain
EXW36_RS05485	COG3428	Bacterial PH domain
EXW36_RS05515	COG3402	PFAM membrane-flanked domain
EXW36_RS05520	COG3428	Bacterial PH domain
EXW36_RS05525	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_RS05530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS05535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW36_RS05540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW36_RS05545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW36_RS05565	COG1309	transcriptional regulator
EXW36_RS05570	COG1511	domain protein
EXW36_RS05605	COG2378	regulation of single-species biofilm formation
EXW36_RS05610	COG1609	Transcriptional regulator
EXW36_RS05620	COG1234	tRNA 3'-trailer cleavage
EXW36_RS05625	COG0095	Lipoate-protein ligase
EXW36_RS05635	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS05650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW36_RS05660	COG4208	sulfate ABC transporter
EXW36_RS05675	COG1408	metallophosphoesterase
EXW36_RS05680	COG1078	dGTPase activity
EXW36_RS05700	COG3708	Transcriptional regulator
EXW36_RS05700	COG2207	Transcriptional regulator
EXW36_RS05705	COG2205	protein histidine kinase activity
EXW36_RS05710	COG0745	RESPONSE REGULATOR receiver
EXW36_RS05725	COG0501	Belongs to the peptidase M48B family
EXW36_RS05730	COG0697	spore germination
EXW36_RS05755	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW36_RS05760	COG2224	Isocitrate lyase
EXW36_RS05770	COG1278	Cold shock
EXW36_RS05780	COG4903	ComK protein
EXW36_RS05785	COG0398	Pfam SNARE associated Golgi protein
EXW36_RS05795	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW36_RS05800	COG1074	ATP-dependent DNA helicase activity
EXW36_RS05850	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW36_RS05875	COG0367	asparagine synthase
EXW36_RS05885	COG0753	catalase activity
EXW36_RS05890	COG0004	ammonium transporteR
EXW36_RS05900	COG1666	GTP binding
EXW36_RS05905	COG2996	Protein conserved in bacteria
EXW36_RS05910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_RS05920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS05935	COG0561	phosphatase activity
EXW36_RS05955	COG2267	carboxylic ester hydrolase activity
EXW36_RS05970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_RS05975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW36_RS05980	COG5504	Zn-dependent protease
EXW36_RS05990	COG0180	Tryptophanyl-tRNA synthetase
EXW36_RS06000	COG4166	transmembrane transport
EXW36_RS06005	COG0601	transmembrane transport
EXW36_RS06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW36_RS06015	COG0444	Belongs to the ABC transporter superfamily
EXW36_RS06020	COG4608	Belongs to the ABC transporter superfamily
EXW36_RS06025	COG0534	Mate efflux family protein
EXW36_RS06030	COG4166	transmembrane transport
EXW36_RS06045	COG0861	Integral membrane protein TerC family
EXW36_RS06050	COG4862	establishment of competence for transformation
EXW36_RS06055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS06065	COG1164	Oligoendopeptidase f
EXW36_RS06080	COG2346	COG2346, Truncated hemoglobins
EXW36_RS06085	COG4116	CYTH
EXW36_RS06095	COG2357	RelA SpoT domain protein
EXW36_RS06105	COG0564	pseudouridine synthase activity
EXW36_RS06115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW36_RS06120	COG0772	Belongs to the SEDS family
EXW36_RS06125	COG1216	Glycosyl transferase, family 2
EXW36_RS06145	COG0463	Glycosyl transferase, family 2
EXW36_RS06145	COG0457	Tetratricopeptide repeat
EXW36_RS06165	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW36_RS06180	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW36_RS06225	COG2153	protein acetylation
EXW36_RS06230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW36_RS06235	COG2382	esterase
EXW36_RS06260	COG5492	domain, Protein
EXW36_RS06265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_RS06275	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW36_RS06275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW36_RS06280	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW36_RS06285	COG0134	indole-3-glycerol-phosphate synthase activity
EXW36_RS06290	COG0135	phosphoribosylanthranilate isomerase activity
EXW36_RS06295	COG0133	tryptophan synthase activity
EXW36_RS06300	COG0159	tryptophan synthase activity
EXW36_RS06310	COG1620	l-lactate permease
EXW36_RS06315	COG5634	Uncharacterized conserved protein (DUF2278)
EXW36_RS06360	COG2226	methyltransferase
EXW36_RS06380	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_RS06385	COG0567	Dehydrogenase, E1 component
EXW36_RS06390	COG1476	TRANSCRIPTIONal
EXW36_RS06430	COG0582	viral genome integration into host DNA
EXW36_RS06510	COG0457	Tetratricopeptide repeat
EXW36_RS06550	COG1686	Belongs to the peptidase S11 family
EXW36_RS06555	COG0681	Belongs to the peptidase S26 family
EXW36_RS06590	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS06600	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW36_RS06605	COG1177	transmembrane transport
EXW36_RS06610	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW36_RS06620	COG2409	Drug exporters of the RND superfamily
EXW36_RS06630	COG0564	pseudouridine synthase activity
EXW36_RS06640	COG2340	Cysteine-rich secretory protein family
EXW36_RS06645	COG0247	lactate metabolic process
EXW36_RS06650	COG0277	FAD linked oxidase domain protein
EXW36_RS06655	COG3835	regulator
EXW36_RS06665	COG0745	RESPONSE REGULATOR receiver
EXW36_RS06670	COG5002	protein histidine kinase activity
EXW36_RS06675	COG2186	Transcriptional regulator
EXW36_RS06680	COG0247	lactate metabolic process
EXW36_RS06685	COG1139	Iron-sulfur cluster binding protein
EXW36_RS06690	COG1556	Lactate utilization protein
EXW36_RS06695	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW36_RS06705	COG2116	formate transmembrane transporter activity
EXW36_RS06710	COG0861	Integral membrane protein TerC family
EXW36_RS06715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_RS06725	COG2030	dehydratase
EXW36_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS06750	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW36_RS06760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_RS06775	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW36_RS06780	COG3842	ATPase activity
EXW36_RS06790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW36_RS06795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW36_RS06805	COG1349	DNA-binding transcription factor activity
EXW36_RS06815	COG0235	Class ii aldolase
EXW36_RS06825	COG2861	carbohydrate metabolic process
EXW36_RS06835	COG3852	Histidine kinase
EXW36_RS06840	COG1846	Transcriptional regulator
EXW36_RS06850	COG2318	DinB family
EXW36_RS06855	COG5002	protein histidine kinase activity
EXW36_RS06860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW36_RS06865	COG0720	synthase
EXW36_RS06875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW36_RS06880	COG4873	Protein conserved in bacteria
EXW36_RS06895	COG0456	acetyltransferase
EXW36_RS06910	COG1780	Probably involved in ribonucleotide reductase function
EXW36_RS06925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW36_RS06930	COG0531	amino acid
EXW36_RS06935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW36_RS06950	COG2204	response regulator
EXW36_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS06965	COG1725	Transcriptional regulator
EXW36_RS06970	COG1131	(ABC) transporter
EXW36_RS06980	COG1131	(ABC) transporter
EXW36_RS06985	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_RS06990	COG1266	CAAX protease self-immunity
EXW36_RS07000	COG1522	sequence-specific DNA binding
EXW36_RS07010	COG1335	isochorismatase
EXW36_RS07020	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_RS07025	COG2070	2-Nitropropane dioxygenase
EXW36_RS07030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW36_RS07035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_RS07040	COG1696	Membrane protein involved in D-alanine export
EXW36_RS07065	COG0716	FMN binding
EXW36_RS07100	COG0534	Mate efflux family protein
EXW36_RS07105	COG1968	undecaprenyl-diphosphatase activity
EXW36_RS07125	COG1846	Transcriptional regulator
EXW36_RS07135	COG1301	dicarboxylic acid transport
EXW36_RS07140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW36_RS07150	COG3874	Sporulation protein YtfJ
EXW36_RS07175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS07180	COG0028	Belongs to the TPP enzyme family
EXW36_RS07185	COG0440	acetolactate synthase activity
EXW36_RS07195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_RS07205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW36_RS07215	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW36_RS07220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW36_RS07230	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW36_RS07235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW36_RS07240	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW36_RS07245	COG0107	imidazoleglycerol-phosphate synthase activity
EXW36_RS07255	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW36_RS07260	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW36_RS07275	COG1183	phosphatidylcholine synthase activity
EXW36_RS07280	COG1368	sulfuric ester hydrolase activity
EXW36_RS07290	COG0019	diaminopimelate decarboxylase activity
EXW36_RS07300	COG0175	sulfate reduction
EXW36_RS07305	COG2046	Belongs to the sulfate adenylyltransferase family
EXW36_RS07310	COG0529	Catalyzes the synthesis of activated sulfate
EXW36_RS07315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW36_RS07335	COG1648	precorrin-2 dehydrogenase activity
EXW36_RS07340	COG0733	neurotransmitter:sodium symporter activity
EXW36_RS07365	COG1757	Na H antiporter
EXW36_RS07380	COG4758	membrane
EXW36_RS07385	COG4585	Histidine kinase
EXW36_RS07390	COG2197	response regulator
EXW36_RS07400	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS07410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW36_RS07450	COG0730	response to heat
EXW36_RS07455	COG0306	phosphate transporter
EXW36_RS07460	COG1392	Phosphate transport regulator
EXW36_RS07465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS07480	COG3852	Histidine kinase
EXW36_RS07485	COG1801	Protein of unknown function DUF72
EXW36_RS07495	COG0582	viral genome integration into host DNA
EXW36_RS07500	COG5002	protein histidine kinase activity
EXW36_RS07515	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW36_RS07515	COG0392	lysyltransferase activity
EXW36_RS07530	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_RS07535	COG1686	Belongs to the peptidase S11 family
EXW36_RS07540	COG2715	membrane protein required for spore maturation
EXW36_RS07545	COG0700	Nucleoside recognition
EXW36_RS07550	COG1187	pseudouridine synthase activity
EXW36_RS07560	COG1333	cytochrome c biogenesis protein
EXW36_RS07565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW36_RS07570	COG0745	RESPONSE REGULATOR receiver
EXW36_RS07575	COG5002	protein histidine kinase activity
EXW36_RS07580	COG2096	Adenosyltransferase
EXW36_RS07585	COG4942	peptidase
EXW36_RS07595	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW36_RS07600	COG1141	Ferredoxin
EXW36_RS07605	COG4955	Helix-turn-helix domain
EXW36_RS07610	COG0514	ATP-dependent DNA helicase (RecQ)
EXW36_RS07615	COG1266	CAAX protease self-immunity
EXW36_RS07625	COG1408	metallophosphoesterase
EXW36_RS07640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW36_RS07660	COG0492	ferredoxin-NADP+ reductase activity
EXW36_RS07665	COG0252	asparaginase activity
EXW36_RS07675	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW36_RS07685	COG1304	FMN binding
EXW36_RS07715	COG1160	GTP binding
EXW36_RS07720	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW36_RS07740	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_RS07750	COG0302	gtp cyclohydrolase
EXW36_RS07755	COG0142	geranyltranstransferase activity
EXW36_RS07760	COG2226	methyltransferase
EXW36_RS07765	COG0142	geranyltranstransferase activity
EXW36_RS07780	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW36_RS07790	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW36_RS07795	COG0457	Tetratricopeptide repeat
EXW36_RS07800	COG5582	Belongs to the UPF0302 family
EXW36_RS07815	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW36_RS07830	COG4347	Protein of unknown function (DUF1405)
EXW36_RS07845	COG2738	Putative neutral zinc metallopeptidase
EXW36_RS07855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS07860	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW36_RS07865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW36_RS07870	COG1803	Methylglyoxal synthase
EXW36_RS07875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_RS07880	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS07885	COG0617	tRNA 3'-terminal CCA addition
EXW36_RS07895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW36_RS07900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW36_RS07910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW36_RS07910	COG1199	ATP-dependent helicase activity
EXW36_RS07930	COG3935	DnaD domain protein
EXW36_RS07935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW36_RS07945	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_RS07945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS07950	COG3331	DNA recombination
EXW36_RS07985	COG4474	Belongs to the UPF0398 family
EXW36_RS07990	COG3599	regulation of cell shape
EXW36_RS08000	COG0116	Belongs to the methyltransferase superfamily
EXW36_RS08010	COG1199	ATP-dependent helicase activity
EXW36_RS08015	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW36_RS08025	COG0024	Methionine aminopeptidase
EXW36_RS08035	COG2233	PERMEase
EXW36_RS08040	COG2311	Membrane
EXW36_RS08050	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_RS08060	COG0456	acetyltransferase
EXW36_RS08070	COG2897	thiosulfate sulfurtransferase activity
EXW36_RS08110	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_RS08135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_RS08150	COG1215	transferase activity, transferring glycosyl groups
EXW36_RS08155	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS08170	COG0454	-acetyltransferase
EXW36_RS08190	COG0328	RNA-DNA hybrid ribonuclease activity
EXW36_RS08225	COG3403	YqcI/YcgG family
EXW36_RS08230	COG1280	lysine exporter protein (LysE YggA)
EXW36_RS08245	COG3162	membrane
EXW36_RS08250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW36_RS08255	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_RS08265	COG0475	glutathione-regulated potassium exporter activity
EXW36_RS08270	COG4978	Transcriptional regulator
EXW36_RS08270	COG0789	Transcriptional regulator
EXW36_RS08280	COG2323	membrane
EXW36_RS08285	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW36_RS08315	COG2814	Major facilitator Superfamily
EXW36_RS08335	COG1923	regulation of RNA biosynthetic process
EXW36_RS08360	COG0784	Response regulator, receiver
EXW36_RS08360	COG0835	chemotaxis
EXW36_RS08390	COG0861	Integral membrane protein TerC family
EXW36_RS08400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW36_RS08420	COG1776	CheC inhibitor of MCP methylation
EXW36_RS08420	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW36_RS08430	COG1338	Plays a role in the flagellum-specific transport system
EXW36_RS08435	COG1987	bacterial-type flagellum assembly
EXW36_RS08445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW36_RS08450	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW36_RS08455	COG1419	protein localization to endoplasmic reticulum
EXW36_RS08460	COG4786	Flagellar basal body rod
EXW36_RS08465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_RS08495	COG0412	Dienelactone hydrolase
EXW36_RS08500	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_RS08515	COG2814	Major facilitator Superfamily
EXW36_RS08525	COG0583	DNA-binding transcription factor activity
EXW36_RS08530	COG3842	ATPase activity
EXW36_RS08580	COG0406	alpha-ribazole phosphatase activity
EXW36_RS08610	COG0367	asparagine synthase
EXW36_RS08640	COG1802	Transcriptional regulator
EXW36_RS08645	COG0697	spore germination
EXW36_RS08655	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS08655	COG1216	Glycosyl transferase, family 2
EXW36_RS08660	COG1757	Na H antiporter
EXW36_RS08690	COG0534	Mate efflux family protein
EXW36_RS08695	COG3340	Belongs to the peptidase S51 family
EXW36_RS08715	COG0785	Cytochrome C biogenesis protein
EXW36_RS08720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS08735	COG3048	D-serine ammonia-lyase activity
EXW36_RS08740	COG2733	membrane
EXW36_RS08775	COG1131	(ABC) transporter
EXW36_RS08790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS08825	COG0528	UMP kinase activity
EXW36_RS08835	COG1027	Aspartate ammonia-lyase
EXW36_RS08840	COG0281	malic enzyme
EXW36_RS08845	COG4191	Histidine kinase
EXW36_RS08850	COG0784	Response regulator, receiver
EXW36_RS08855	COG1846	Transcriptional regulator
EXW36_RS08865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_RS08875	COG2502	aspartate--ammonia ligase
EXW36_RS08910	COG1051	belongs to the nudix hydrolase family
EXW36_RS08915	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS08925	COG2814	Major facilitator Superfamily
EXW36_RS08955	COG0477	Major facilitator Superfamily
EXW36_RS08960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_RS08970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW36_RS08975	COG2223	nitrite transmembrane transporter activity
EXW36_RS08980	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_RS08995	COG2244	polysaccharide biosynthetic process
EXW36_RS09000	COG0733	neurotransmitter:sodium symporter activity
EXW36_RS09010	COG5566	PFAM Mor transcription activator
EXW36_RS09015	COG2323	membrane
EXW36_RS09030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_RS09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS09045	COG0028	Belongs to the TPP enzyme family
EXW36_RS09060	COG0129	dihydroxy-acid dehydratase activity
EXW36_RS09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW36_RS09090	COG2814	Major facilitator Superfamily
EXW36_RS09095	COG3384	dioxygenase
EXW36_RS09120	COG4166	transmembrane transport
EXW36_RS09125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS09135	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW36_RS09140	COG1054	Belongs to the UPF0176 family
EXW36_RS09150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW36_RS09155	COG0531	amino acid
EXW36_RS09190	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_RS09205	COG4257	antibiotic catabolic process
EXW36_RS09210	COG2390	Transcriptional regulator
EXW36_RS09220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW36_RS09225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS09230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW36_RS09245	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW36_RS09260	COG0583	DNA-binding transcription factor activity
EXW36_RS09275	COG0006	proline dipeptidase activity
EXW36_RS09280	COG2132	Multicopper oxidase
EXW36_RS09290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_RS09310	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS09320	COG1276	copper resistance
EXW36_RS09320	COG2372	response to copper ion
EXW36_RS09325	COG4549	nuclear export factor GLE1
EXW36_RS09335	COG0697	spore germination
EXW36_RS09340	COG0583	DNA-binding transcription factor activity
EXW36_RS09345	COG1959	2 iron, 2 sulfur cluster binding
EXW36_RS09350	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW36_RS09355	COG0778	Nitroreductase
EXW36_RS09370	COG0628	permease
EXW36_RS09385	COG1231	oxidoreductase activity
EXW36_RS09390	COG0523	cobalamin synthesis protein
EXW36_RS09400	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS09405	COG2030	dehydratase
EXW36_RS09410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_RS09425	COG0411	ABC transporter
EXW36_RS09445	COG0583	DNA-binding transcription factor activity
EXW36_RS09455	COG1942	4-Oxalocrotonate Tautomerase
EXW36_RS09470	COG0346	lactoylglutathione lyase activity
EXW36_RS09480	COG1271	oxidase subunit
EXW36_RS09485	COG1294	oxidase, subunit
EXW36_RS09490	COG4988	ABC transporter
EXW36_RS09495	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW36_RS09525	COG1686	Belongs to the peptidase S11 family
EXW36_RS09540	COG0791	NLP P60 protein
EXW36_RS09540	COG1388	LysM domain
EXW36_RS09550	COG1132	(ABC) transporter
EXW36_RS09555	COG0745	RESPONSE REGULATOR receiver
EXW36_RS09560	COG5002	protein histidine kinase activity
EXW36_RS09565	COG0300	oxidoreductase activity
EXW36_RS09570	COG4122	O-methyltransferase activity
EXW36_RS09600	COG0460	homoserine dehydrogenase
EXW36_RS09610	COG0083	homoserine kinase activity
EXW36_RS09625	COG1316	TRANSCRIPTIONal
EXW36_RS09645	COG1285	pathogenesis
EXW36_RS09650	COG1247	-acetyltransferase
EXW36_RS09670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_RS09680	COG1082	Xylose isomerase domain protein TIM barrel
EXW36_RS09690	COG2814	Major facilitator Superfamily
EXW36_RS09695	COG1279	arginine transmembrane transporter activity
EXW36_RS09700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS09710	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW36_RS09740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW36_RS09745	COG0577	efflux transmembrane transporter activity
EXW36_RS09750	COG2002	toxin-antitoxin pair type II binding
EXW36_RS09755	COG1404	Belongs to the peptidase S8 family
EXW36_RS09760	COG0640	Transcriptional regulator
EXW36_RS09765	COG0667	Aldo Keto reductase
EXW36_RS09810	COG3949	Membrane
EXW36_RS09815	COG0783	Belongs to the Dps family
EXW36_RS09830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW36_RS09840	COG1231	oxidoreductase activity
EXW36_RS09845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS09850	COG4989	oxidoreductase activity
EXW36_RS09855	COG0523	cobalamin synthesis protein
EXW36_RS09860	COG0456	acetyltransferase
EXW36_RS09865	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW36_RS09890	COG1136	(ABC) transporter
EXW36_RS09895	COG0577	efflux transmembrane transporter activity
EXW36_RS09900	COG0745	RESPONSE REGULATOR receiver
EXW36_RS09905	COG2205	protein histidine kinase activity
EXW36_RS09910	COG1902	pentaerythritol trinitrate reductase activity
EXW36_RS09915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW36_RS09925	COG4166	transmembrane transport
EXW36_RS09930	COG0346	lactoylglutathione lyase activity
EXW36_RS09940	COG0406	alpha-ribazole phosphatase activity
EXW36_RS09950	COG5337	Spore coat protein CotH
EXW36_RS09955	COG1051	belongs to the nudix hydrolase family
EXW36_RS09960	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS09965	COG2244	polysaccharide biosynthetic process
EXW36_RS09975	COG0701	Predicted permease
EXW36_RS09980	COG3689	TIGRFAM TIGR03943 family protein
EXW36_RS09985	COG1607	acyl-coa hydrolase
EXW36_RS09995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS10010	COG0702	epimerase
EXW36_RS10015	COG2839	Protein conserved in bacteria
EXW36_RS10020	COG1253	flavin adenine dinucleotide binding
EXW36_RS10045	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS10050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_RS10065	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS10075	COG1876	peptidase activity
EXW36_RS10080	COG0494	nUDIX hydrolase
EXW36_RS10090	COG2211	Major facilitator Superfamily
EXW36_RS10105	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS10115	COG0561	phosphatase activity
EXW36_RS10120	COG1846	Transcriptional regulator
EXW36_RS10125	COG2814	Major facilitator Superfamily
EXW36_RS10135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW36_RS10150	COG1819	glycosyl
EXW36_RS10155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS10160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS10185	COG0456	acetyltransferase
EXW36_RS10205	COG3874	Sporulation protein YtfJ
EXW36_RS10230	COG2226	methyltransferase
EXW36_RS10260	COG0604	alcohol dehydrogenase
EXW36_RS10265	COG1595	DNA-templated transcription, initiation
EXW36_RS10290	COG0426	domain, Protein
EXW36_RS10290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW36_RS10300	COG0386	Belongs to the glutathione peroxidase family
EXW36_RS10305	COG1305	Transglutaminase-like
EXW36_RS10310	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW36_RS10315	COG0714	Associated with various cellular activities
EXW36_RS10330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW36_RS10335	COG1140	nitrate reductase beta subunit
EXW36_RS10340	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW36_RS10345	COG2181	nitrate reductase activity
EXW36_RS10350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW36_RS10355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW36_RS10360	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_RS10365	COG0303	'Molybdopterin
EXW36_RS10370	COG0314	molybdopterin synthase activity
EXW36_RS10380	COG2223	nitrite transmembrane transporter activity
EXW36_RS10405	COG1648	precorrin-2 dehydrogenase activity
EXW36_RS10415	COG1587	Uroporphyrinogen-III synthase
EXW36_RS10415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW36_RS10420	COG2146	nitrite reductase [NAD(P)H] activity
EXW36_RS10425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW36_RS10440	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW36_RS10470	COG2359	stage V sporulation protein S
EXW36_RS10480	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS10490	COG5444	nuclease activity
EXW36_RS10500	COG1418	mRNA catabolic process
EXW36_RS10505	COG0488	(ABC) transporter
EXW36_RS10540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EXW36_RS10555	COG0515	serine threonine protein kinase
EXW36_RS10555	COG2815	serine threonine protein kinase
EXW36_RS10565	COG1413	lyase activity
EXW36_RS10580	COG2136	Putative SAM-dependent methyltransferase
EXW36_RS10580	COG2521	methyltransferase
EXW36_RS10585	COG0018	arginyl-trna synthetase
EXW36_RS10635	COG0017	Asparaginyl-tRNA synthetase
EXW36_RS10640	COG0733	neurotransmitter:sodium symporter activity
EXW36_RS10665	COG2610	gluconate transmembrane transporter activity
EXW36_RS10675	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_RS10685	COG0456	acetyltransferase
EXW36_RS10690	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW36_RS10700	COG1131	(ABC) transporter
EXW36_RS10705	COG4473	ABC transporter
EXW36_RS10715	COG0546	phosphoglycolate phosphatase activity
EXW36_RS10730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_RS10745	COG0768	penicillin binding
EXW36_RS10755	COG0204	Acyl-transferase
EXW36_RS10760	COG1272	protein, Hemolysin III
EXW36_RS10765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW36_RS10770	COG0805	protein transport
EXW36_RS10790	COG1999	signal sequence binding
EXW36_RS10795	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW36_RS10800	COG0367	asparagine synthase
EXW36_RS10815	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS10820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS10825	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS10845	COG1335	isochorismatase
EXW36_RS10855	COG0668	transmembrane transport
EXW36_RS10860	COG2203	Gaf domain
EXW36_RS10860	COG4585	Histidine kinase
EXW36_RS10865	COG2197	response regulator
EXW36_RS10870	COG1737	Transcriptional regulator
EXW36_RS10875	COG1064	alcohol dehydrogenase
EXW36_RS10890	COG1070	Carbohydrate kinase
EXW36_RS10900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW36_RS10920	COG0517	IMP dehydrogenase activity
EXW36_RS10920	COG1125	glycine betaine transport
EXW36_RS10925	COG1174	glycine betaine transport
EXW36_RS10960	COG1253	flavin adenine dinucleotide binding
EXW36_RS10965	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS10970	COG5506	Protein of unknown function (DUF1694)
EXW36_RS10985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_RS10990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW36_RS10995	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW36_RS11000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_RS11005	COG0456	acetyltransferase
EXW36_RS11010	COG3829	transcription factor binding
EXW36_RS11015	COG1509	lysine 2,3-aminomutase activity
EXW36_RS11025	COG4479	Belongs to the UPF0346 family
EXW36_RS11050	COG4991	sh3 domain protein
EXW36_RS11050	COG3064	Membrane
EXW36_RS11050	COG0515	serine threonine protein kinase
EXW36_RS11060	COG0671	phosphoesterase, PA-phosphatase related
EXW36_RS11065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_RS11070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS11125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW36_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS11170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS11170	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_RS11180	COG2814	Major facilitator Superfamily
EXW36_RS11190	COG0372	Belongs to the citrate synthase family
EXW36_RS11195	COG2079	MmgE PrpD family protein
EXW36_RS11200	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW36_RS11205	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS11210	COG2084	Dehydrogenase
EXW36_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS11220	COG1280	lysine exporter protein (LysE YggA)
EXW36_RS11225	COG1024	Enoyl-CoA hydratase
EXW36_RS11240	COG0420	3'-5' exonuclease activity
EXW36_RS11265	COG2223	nitrite transmembrane transporter activity
EXW36_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS11275	COG1169	isochorismate synthase
EXW36_RS11280	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW36_RS11285	COG3433	isochorismatase activity
EXW36_RS11285	COG1535	isochorismatase
EXW36_RS11290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW36_RS11295	COG3251	PFAM MbtH domain protein
EXW36_RS11300	COG2814	Major facilitator Superfamily
EXW36_RS11315	COG0776	regulation of translation
EXW36_RS11325	COG2318	DinB family
EXW36_RS11330	COG1115	amino acid carrier protein
EXW36_RS11345	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_RS11355	COG1187	pseudouridine synthase activity
EXW36_RS11360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW36_RS11365	COG3655	Transcriptional regulator
EXW36_RS11375	COG1136	(ABC) transporter
EXW36_RS11385	COG0596	Alpha beta hydrolase
EXW36_RS11400	COG0028	Belongs to the TPP enzyme family
EXW36_RS11410	COG2226	methyltransferase
EXW36_RS11420	COG1253	flavin adenine dinucleotide binding
EXW36_RS11450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW36_RS11470	COG1846	Transcriptional regulator
EXW36_RS11480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS11485	COG1309	transcriptional regulator
EXW36_RS11515	COG1247	-acetyltransferase
EXW36_RS11545	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW36_RS11555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS11755	COG2002	toxin-antitoxin pair type II binding
EXW36_RS11785	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW36_RS11930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_RS11995	COG0561	phosphatase activity
EXW36_RS12005	COG0583	DNA-binding transcription factor activity
EXW36_RS12010	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW36_RS12020	COG0583	DNA-binding transcription factor activity
EXW36_RS12025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW36_RS12030	COG2258	MOSC domain
EXW36_RS12045	COG1132	(ABC) transporter
EXW36_RS12050	COG1132	(ABC) transporter
EXW36_RS12065	COG0189	ligase activity
EXW36_RS12090	COG1396	sequence-specific DNA binding
EXW36_RS12125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW36_RS12130	COG1595	DNA-templated transcription, initiation
EXW36_RS12155	COG1649	PFAM Uncharacterised BCR, COG1649
EXW36_RS12175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW36_RS12180	COG2971	BadF BadG BcrA BcrD
EXW36_RS12190	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW36_RS12230	COG1309	transcriptional regulator
EXW36_RS12245	COG1136	(ABC) transporter
EXW36_RS12250	COG0500	methyltransferase
EXW36_RS12250	COG3615	Tellurite resistance protein tehB
EXW36_RS12260	COG0693	protein deglycase activity
EXW36_RS12270	COG0588	phosphoglycerate mutase activity
EXW36_RS12295	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_RS12305	COG0110	maltose O-acetyltransferase activity
EXW36_RS12310	COG1136	(ABC) transporter
EXW36_RS12335	COG1686	Belongs to the peptidase S11 family
EXW36_RS12360	COG0768	penicillin binding
EXW36_RS12365	COG0745	RESPONSE REGULATOR receiver
EXW36_RS12370	COG2205	protein histidine kinase activity
EXW36_RS12375	COG1136	(ABC) transporter
EXW36_RS12380	COG0577	efflux transmembrane transporter activity
EXW36_RS12390	COG1595	DNA-templated transcription, initiation
EXW36_RS12400	COG0768	penicillin binding
EXW36_RS12405	COG0768	penicillin binding
EXW36_RS12440	COG1252	NADH dehydrogenase
EXW36_RS12445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS12445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS12460	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW36_RS12460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS12480	COG1136	(ABC) transporter
EXW36_RS12485	COG0577	efflux transmembrane transporter activity
EXW36_RS12505	COG1136	(ABC) transporter
EXW36_RS12525	COG2723	6-phospho-beta-galactosidase activity
EXW36_RS12600	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS12610	COG2239	Acts as a magnesium transporter
EXW36_RS12625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW36_RS12640	COG0697	spore germination
EXW36_RS12665	COG3397	chitin binding
EXW36_RS12670	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_RS12680	COG1408	metallophosphoesterase
EXW36_RS12690	COG1131	(ABC) transporter
EXW36_RS12700	COG1309	transcriptional regulator
EXW36_RS12710	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS12715	COG0439	Biotin carboxylase
EXW36_RS12720	COG0511	ligase activity, forming carbon-carbon bonds
EXW36_RS12725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_RS12730	COG1024	Enoyl-CoA hydratase
EXW36_RS12735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW36_RS12740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_RS12785	COG0572	uridine kinase
EXW36_RS12820	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_RS12850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW36_RS12875	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS12880	COG1733	regulation of RNA biosynthetic process
EXW36_RS12905	COG1309	transcriptional regulator
EXW36_RS12920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_RS12935	COG0697	spore germination
EXW36_RS12940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS12970	COG2323	membrane
EXW36_RS12985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS12990	COG0697	spore germination
EXW36_RS13010	COG0201	protein transport
EXW36_RS13020	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS13025	COG3227	Zinc metalloprotease (Elastase)
EXW36_RS13030	COG1523	belongs to the glycosyl hydrolase 13 family
EXW36_RS13045	COG0076	glutamate decarboxylase activity
EXW36_RS13050	COG0657	acetylesterase activity
EXW36_RS13055	COG1073	alpha beta
EXW36_RS13065	COG0577	efflux transmembrane transporter activity
EXW36_RS13070	COG1136	(ABC) transporter
EXW36_RS13100	COG5002	protein histidine kinase activity
EXW36_RS13105	COG0745	RESPONSE REGULATOR receiver
EXW36_RS13110	COG1011	Hydrolase
EXW36_RS13130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_RS13135	COG1183	phosphatidylcholine synthase activity
EXW36_RS13145	COG1132	(ABC) transporter
EXW36_RS13155	COG3961	Belongs to the TPP enzyme family
EXW36_RS13175	COG0322	excinuclease ABC activity
EXW36_RS13200	COG2318	DinB family
EXW36_RS13215	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW36_RS13240	COG3878	Protein conserved in bacteria
EXW36_RS13265	COG1051	belongs to the nudix hydrolase family
EXW36_RS13270	COG0592	DNA-directed DNA polymerase activity
EXW36_RS13275	COG2816	NAD+ diphosphatase activity
EXW36_RS13285	COG2223	nitrite transmembrane transporter activity
EXW36_RS13295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_RS13305	COG0494	nUDIX hydrolase
EXW36_RS13325	COG0697	spore germination
EXW36_RS13330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS13340	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_RS13355	COG2814	Major facilitator Superfamily
EXW36_RS13395	COG0768	penicillin binding
EXW36_RS13400	COG0671	phosphoesterase, PA-phosphatase related
EXW36_RS13405	COG0604	alcohol dehydrogenase
EXW36_RS13410	COG5002	protein histidine kinase activity
EXW36_RS13415	COG0745	RESPONSE REGULATOR receiver
EXW36_RS13425	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_RS13435	COG2205	protein histidine kinase activity
EXW36_RS13450	COG1122	ATPase activity
EXW36_RS13455	COG4720	Psort location CytoplasmicMembrane, score
EXW36_RS13460	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_RS13465	COG1819	glycosyl
EXW36_RS13475	COG0768	penicillin binding
EXW36_RS13480	COG5002	protein histidine kinase activity
EXW36_RS13485	COG0561	phosphatase activity
EXW36_RS13530	COG2124	cytochrome p450
EXW36_RS13575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW36_RS13585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS13590	COG0460	homoserine dehydrogenase
EXW36_RS13610	COG0577	efflux transmembrane transporter activity
EXW36_RS13615	COG1136	(ABC) transporter
EXW36_RS13625	COG0488	(ABC) transporter
EXW36_RS13630	COG0667	Aldo Keto reductase
EXW36_RS13635	COG0583	DNA-binding transcription factor activity
EXW36_RS13640	COG2205	protein histidine kinase activity
EXW36_RS13645	COG0745	RESPONSE REGULATOR receiver
EXW36_RS13655	COG3773	Cell wall hydrolase
EXW36_RS13660	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW36_RS13670	COG3386	PFAM SMP-30 Gluconolaconase
EXW36_RS13710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS13725	COG2959	enzyme of heme biosynthesis
EXW36_RS13750	COG3483	tryptophan 2,3-dioxygenase activity
EXW36_RS13755	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW36_RS13760	COG3844	kynureninase activity
EXW36_RS13765	COG1309	transcriptional regulator
EXW36_RS13780	COG3284	Transcriptional regulator
EXW36_RS13795	COG1349	DNA-binding transcription factor activity
EXW36_RS13825	COG1959	2 iron, 2 sulfur cluster binding
EXW36_RS13840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW36_RS13845	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_RS13850	COG0022	dehydrogenase e1 component
EXW36_RS13855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS13880	COG0456	acetyltransferase
EXW36_RS13880	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_RS13910	COG4176	ABC-type proline glycine betaine transport system permease component
EXW36_RS13915	COG0517	IMP dehydrogenase activity
EXW36_RS13915	COG4175	Glycine betaine
EXW36_RS13940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW36_RS13945	COG2153	protein acetylation
EXW36_RS13950	COG3397	chitin binding
EXW36_RS13960	COG1819	glycosyl
EXW36_RS13975	COG2205	protein histidine kinase activity
EXW36_RS13980	COG2315	Protein conserved in bacteria
EXW36_RS14025	COG3973	AAA domain
EXW36_RS14035	COG2105	PFAM AIG2 family protein
EXW36_RS14040	COG0514	ATP-dependent DNA helicase (RecQ)
EXW36_RS14065	COG4637	Psort location Cytoplasmic, score
EXW36_RS14075	COG1227	inorganic diphosphatase activity
EXW36_RS14080	COG3397	chitin binding
EXW36_RS14085	COG2318	DinB family
EXW36_RS14105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW36_RS14110	COG1115	amino acid carrier protein
EXW36_RS14115	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS14120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW36_RS14130	COG3938	Belongs to the proline racemase family
EXW36_RS14135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_RS14175	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS14190	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW36_RS14195	COG4166	transmembrane transport
EXW36_RS14205	COG4948	Mandelate Racemase Muconate Lactonizing
EXW36_RS14225	COG0667	Aldo Keto reductase
EXW36_RS14265	COG2936	dipeptidyl-peptidase activity
EXW36_RS14275	COG0745	RESPONSE REGULATOR receiver
EXW36_RS14305	COG1164	Oligoendopeptidase f
EXW36_RS14310	COG0531	amino acid
EXW36_RS14315	COG1522	sequence-specific DNA binding
EXW36_RS14330	COG1307	EDD domain protein, DegV family
EXW36_RS14355	COG1335	isochorismatase
EXW36_RS14370	COG2814	Major facilitator Superfamily
EXW36_RS14380	COG1664	Polymer-forming cytoskeletal
EXW36_RS14385	COG0789	Transcriptional regulator
EXW36_RS14390	COG4533	DNA binding
EXW36_RS14395	COG2814	Major facilitator Superfamily
EXW36_RS14395	COG0477	Major facilitator Superfamily
EXW36_RS14415	COG2261	transglycosylase associated protein
EXW36_RS14430	COG2226	methyltransferase
EXW36_RS14465	COG0436	Aminotransferase
EXW36_RS14470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW36_RS14495	COG1131	(ABC) transporter
EXW36_RS14500	COG2188	Transcriptional regulator
EXW36_RS14545	COG0628	permease
EXW36_RS14590	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW36_RS14600	COG0697	spore germination
EXW36_RS14605	COG2318	DinB family
EXW36_RS14655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_RS14665	COG2814	Major facilitator Superfamily
EXW36_RS14670	COG1368	sulfuric ester hydrolase activity
EXW36_RS14685	COG0488	(ABC) transporter
EXW36_RS14690	COG1033	growth of symbiont in host cell
EXW36_RS14690	COG2409	Drug exporters of the RND superfamily
EXW36_RS14695	COG1309	transcriptional regulator
EXW36_RS14700	COG0494	nUDIX hydrolase
EXW36_RS14720	COG0287	Prephenate dehydrogenase
EXW36_RS14735	COG1605	Chorismate mutase
EXW36_RS14735	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW36_RS14770	COG3584	3D domain protein
EXW36_RS14770	COG1388	LysM domain
EXW36_RS14780	COG0346	lactoylglutathione lyase activity
EXW36_RS14790	COG0431	NADPH-dependent FMN reductase
EXW36_RS14820	COG0579	oxidoreductase
EXW36_RS14825	COG1879	ABC-type sugar transport system periplasmic component
EXW36_RS14840	COG1129	ABC transporter
EXW36_RS14845	COG2390	Transcriptional regulator
EXW36_RS14865	COG2226	methyltransferase
EXW36_RS14885	COG2329	Antibiotic biosynthesis monooxygenase
EXW36_RS14910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS14915	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW36_RS14920	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW36_RS14925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_RS14930	COG3239	Fatty acid desaturase
EXW36_RS14955	COG3842	ATPase activity
EXW36_RS14980	COG1175	transmembrane transport
EXW36_RS14985	COG1349	DNA-binding transcription factor activity
EXW36_RS14995	COG3655	Transcriptional regulator
EXW36_RS15020	COG3279	Response regulator of the LytR AlgR family
EXW36_RS15035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS15040	COG0346	lactoylglutathione lyase activity
EXW36_RS15065	COG0714	Associated with various cellular activities
EXW36_RS15085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW36_RS15090	COG0753	catalase activity
EXW36_RS15100	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW36_RS15125	COG0714	Associated with various cellular activities
EXW36_RS15135	COG0778	Nitroreductase
EXW36_RS15140	COG1846	Transcriptional regulator
EXW36_RS15155	COG0494	nUDIX hydrolase
EXW36_RS15175	COG1725	Transcriptional regulator
EXW36_RS15205	COG2207	Transcriptional regulator
EXW36_RS15210	COG0456	acetyltransferase
EXW36_RS15225	COG0697	spore germination
EXW36_RS15230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS15235	COG1671	Belongs to the UPF0178 family
EXW36_RS15255	COG0814	amino acid
EXW36_RS15260	COG0697	spore germination
EXW36_RS15275	COG0642	Histidine kinase
EXW36_RS15280	COG0745	RESPONSE REGULATOR receiver
EXW36_RS15285	COG0596	Alpha beta hydrolase
EXW36_RS15295	COG0456	acetyltransferase
EXW36_RS15295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_RS15320	COG0730	response to heat
EXW36_RS15330	COG0833	amino acid
EXW36_RS15340	COG4335	DNA alkylation repair
EXW36_RS15365	COG0681	Belongs to the peptidase S26 family
EXW36_RS15370	COG0768	penicillin binding
EXW36_RS15385	COG3104	oligopeptide transport
EXW36_RS15390	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW36_RS15405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW36_RS15410	COG1984	allophanate hydrolase subunit 2
EXW36_RS15415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW36_RS15420	COG1414	Transcriptional regulator
EXW36_RS15435	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS15460	COG0640	Transcriptional regulator
EXW36_RS15470	COG3314	Sporulation integral membrane protein YlbJ
EXW36_RS15490	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW36_RS15495	COG0577	efflux transmembrane transporter activity
EXW36_RS15500	COG0577	efflux transmembrane transporter activity
EXW36_RS15505	COG1136	(ABC) transporter
EXW36_RS15540	COG3848	Pyruvate phosphate dikinase
EXW36_RS15540	COG0574	Belongs to the PEP-utilizing enzyme family
EXW36_RS15550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_RS15575	COG5002	protein histidine kinase activity
EXW36_RS15580	COG0745	RESPONSE REGULATOR receiver
EXW36_RS15590	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW36_RS15610	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW36_RS15615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW36_RS15620	COG1121	(ABC) transporter
EXW36_RS15640	COG0798	PFAM Bile acid sodium symporter
EXW36_RS15645	COG0346	lactoylglutathione lyase activity
EXW36_RS15650	COG0640	Transcriptional regulator
EXW36_RS15665	COG1309	transcriptional regulator
EXW36_RS15670	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS15675	COG1522	sequence-specific DNA binding
EXW36_RS15690	COG0346	lactoylglutathione lyase activity
EXW36_RS15720	COG0745	RESPONSE REGULATOR receiver
EXW36_RS15725	COG3850	Histidine kinase
EXW36_RS15725	COG5002	protein histidine kinase activity
EXW36_RS15755	COG1073	alpha beta
EXW36_RS15760	COG0814	amino acid
EXW36_RS15765	COG1760	l-serine dehydratase
EXW36_RS15770	COG1760	l-serine dehydratase
EXW36_RS15780	COG5002	protein histidine kinase activity
EXW36_RS15785	COG0745	RESPONSE REGULATOR receiver
EXW36_RS15795	COG5002	protein histidine kinase activity
EXW36_RS15820	COG4977	sequence-specific DNA binding
EXW36_RS15860	COG2814	Major facilitator Superfamily
EXW36_RS15875	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW36_RS15900	COG1522	sequence-specific DNA binding
EXW36_RS15910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW36_RS15925	COG1136	(ABC) transporter
EXW36_RS15930	COG0577	efflux transmembrane transporter activity
EXW36_RS15950	COG3850	Histidine kinase
EXW36_RS15950	COG5002	protein histidine kinase activity
EXW36_RS15960	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS15990	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_RS16010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW36_RS16045	COG2814	Major facilitator Superfamily
EXW36_RS16130	COG2849	repeat protein
EXW36_RS16230	COG0477	Major facilitator Superfamily
EXW36_RS16245	COG1846	Transcriptional regulator
EXW36_RS16250	COG2814	Major facilitator Superfamily
EXW36_RS16270	COG0640	Transcriptional regulator
EXW36_RS16295	COG1329	Transcriptional regulator
EXW36_RS16350	COG5002	protein histidine kinase activity
EXW36_RS16365	COG1136	(ABC) transporter
EXW36_RS16380	COG1131	(ABC) transporter
EXW36_RS16455	COG0789	Transcriptional regulator
EXW36_RS16515	COG4187	Peptidase family M20/M25/M40
EXW36_RS16530	COG2031	fatty acid transporter
EXW36_RS16540	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_RS16590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW36_RS16595	COG1288	antiporter activity
EXW36_RS16600	COG2356	endonuclease I
EXW36_RS16605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_RS16625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW36_RS16645	COG1785	Belongs to the alkaline phosphatase family
EXW36_RS16650	COG0778	Nitroreductase
EXW36_RS16655	COG1733	regulation of RNA biosynthetic process
EXW36_RS16675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS16685	COG1131	(ABC) transporter
EXW36_RS16715	COG1595	DNA-templated transcription, initiation
EXW36_RS16730	COG1011	Hydrolase
EXW36_RS16735	COG2365	Tyrosine phosphatase family
EXW36_RS16760	COG0346	lactoylglutathione lyase activity
EXW36_RS16765	COG1940	carbohydrate kinase activity
EXW36_RS16770	COG0738	Major facilitator superfamily
EXW36_RS16775	COG0110	maltose O-acetyltransferase activity
EXW36_RS16790	COG0628	permease
EXW36_RS16795	COG2261	transglycosylase associated protein
EXW36_RS16810	COG1720	tRNA m6t6A37 methyltransferase activity
EXW36_RS16830	COG0477	Major facilitator Superfamily
EXW36_RS16845	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW36_RS16855	COG1253	flavin adenine dinucleotide binding
EXW36_RS16860	COG0789	Transcriptional regulator
EXW36_RS16870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW36_RS16905	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW36_RS16910	COG3813	Protein conserved in bacteria
EXW36_RS16915	COG2706	6-phosphogluconolactonase activity
EXW36_RS16920	COG1070	Carbohydrate kinase
EXW36_RS16930	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW36_RS16935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW36_RS16950	COG0814	amino acid
EXW36_RS16975	COG1151	hydroxylamine reductase activity
EXW36_RS17005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_RS17015	COG2072	flavoprotein involved in K transport
EXW36_RS17060	COG1695	Transcriptional regulator
EXW36_RS17065	COG0604	alcohol dehydrogenase
EXW36_RS17070	COG1113	amino acid transport
EXW36_RS17080	COG2814	Major facilitator Superfamily
EXW36_RS17090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS17105	COG0534	Mate efflux family protein
EXW36_RS17110	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS17115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW36_RS17130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_RS17135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_RS17155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS17160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS17165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS17190	COG0583	DNA-binding transcription factor activity
EXW36_RS17215	COG1193	negative regulation of DNA recombination
EXW36_RS17225	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW36_RS17230	COG1164	Oligoendopeptidase f
EXW36_RS17235	COG2957	Belongs to the agmatine deiminase family
EXW36_RS17255	COG3781	membrane
EXW36_RS17270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW36_RS17305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW36_RS17310	COG0640	Transcriptional regulator
EXW36_RS17315	COG0604	alcohol dehydrogenase
EXW36_RS17320	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW36_RS17335	COG2808	Putative FMN-binding domain
EXW36_RS17340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_RS17350	COG0277	FAD linked oxidase domain protein
EXW36_RS17370	COG1285	pathogenesis
EXW36_RS17380	COG2514	catechol 2,3-dioxygenase activity
EXW36_RS17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS17390	COG1126	abc transporter atp-binding protein
EXW36_RS17395	COG0765	amino acid transport
EXW36_RS17400	COG2720	vancomycin resistance protein
EXW36_RS17425	COG1278	Cold shock
EXW36_RS17435	COG0716	FMN binding
EXW36_RS17445	COG0494	nUDIX hydrolase
EXW36_RS17465	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS17475	COG0165	Argininosuccinate lyase
EXW36_RS17490	COG4145	pantothenate transmembrane transporter activity
EXW36_RS17500	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS17505	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS17515	COG1657	PFAM Prenyltransferase squalene oxidase
EXW36_RS17520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW36_RS17525	COG2962	Rard protein
EXW36_RS17530	COG3326	Membrane
EXW36_RS17535	COG0531	amino acid
EXW36_RS17570	COG2226	methyltransferase
EXW36_RS17575	COG4166	transmembrane transport
EXW36_RS17580	COG4166	transmembrane transport
EXW36_RS17585	COG4166	transmembrane transport
EXW36_RS17590	COG1316	TRANSCRIPTIONal
EXW36_RS17600	COG1595	DNA-templated transcription, initiation
EXW36_RS17610	COG1131	(ABC) transporter
EXW36_RS17630	COG0673	inositol 2-dehydrogenase activity
EXW36_RS17635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW36_RS17640	COG0187	DNA topoisomerase II activity
EXW36_RS17645	COG1832	CoA-binding protein
EXW36_RS17650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_RS17655	COG0745	RESPONSE REGULATOR receiver
EXW36_RS17665	COG1328	CTP reductase activity
EXW36_RS17675	COG4841	protein insertion into membrane
EXW36_RS17680	COG0824	Thioesterase
EXW36_RS17705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS17725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW36_RS17755	COG2211	Major facilitator Superfamily
EXW36_RS17765	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW36_RS17780	COG0183	Belongs to the thiolase family
EXW36_RS17785	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS17790	COG1268	BioY protein
EXW36_RS17795	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS17800	COG1396	sequence-specific DNA binding
EXW36_RS17820	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW36_RS17840	COG0830	nickel cation binding
EXW36_RS17880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS17890	COG5002	protein histidine kinase activity
EXW36_RS17900	COG0400	carboxylic ester hydrolase activity
EXW36_RS17905	COG0346	lactoylglutathione lyase activity
EXW36_RS17910	COG0069	glutamate synthase activity
EXW36_RS17915	COG1902	pentaerythritol trinitrate reductase activity
EXW36_RS17925	COG1329	Transcriptional regulator
EXW36_RS17930	COG0010	Belongs to the arginase family
EXW36_RS17940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW36_RS17945	COG2986	histidine ammonia-lyase
EXW36_RS17955	COG2226	methyltransferase
EXW36_RS17980	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW36_RS17985	COG0785	Cytochrome C biogenesis protein
EXW36_RS18000	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_RS18005	COG1131	(ABC) transporter
EXW36_RS18015	COG0583	DNA-binding transcription factor activity
EXW36_RS18025	COG1346	cytolysis
EXW36_RS18040	COG0730	response to heat
EXW36_RS18050	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_RS18050	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS18070	COG1132	(ABC) transporter
EXW36_RS18075	COG1132	(ABC) transporter
EXW36_RS18080	COG3763	UPF0154 protein
EXW36_RS18100	COG3639	organic phosphonate transmembrane transporter activity
EXW36_RS18110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS18115	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS18125	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW36_RS18130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW36_RS18145	COG1695	Transcriptional regulator
EXW36_RS18150	COG0174	glutamine synthetase
EXW36_RS18155	COG0789	Transcriptional regulator
EXW36_RS18160	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW36_RS18165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW36_RS18170	COG2860	membrane
EXW36_RS18180	COG0464	growth
EXW36_RS18200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW36_RS18210	COG1388	LysM domain
EXW36_RS18210	COG3584	3D domain protein
EXW36_RS18215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW36_RS18215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW36_RS18215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_RS18220	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW36_RS18225	COG1349	DNA-binding transcription factor activity
EXW36_RS18230	COG1979	alcohol dehydrogenase
EXW36_RS18235	COG2322	membrane
EXW36_RS18245	COG1113	amino acid transport
EXW36_RS18260	COG1408	metallophosphoesterase
EXW36_RS18265	COG2116	formate transmembrane transporter activity
EXW36_RS18280	COG2217	Heavy metal translocating P-type atpase
EXW36_RS18285	COG2608	mercury ion transmembrane transporter activity
EXW36_RS18290	COG1937	Protein conserved in bacteria
EXW36_RS18320	COG4566	intracellular signal transduction
EXW36_RS18325	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW36_RS18330	COG2819	hydrolase of the alpha beta superfamily
EXW36_RS18335	COG1120	ATPase activity
EXW36_RS18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS18345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS18350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS18355	COG0708	Exodeoxyribonuclease III
EXW36_RS18360	COG2169	Transcriptional regulator
EXW36_RS18365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW36_RS18370	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW36_RS18375	COG2706	6-phosphogluconolactonase activity
EXW36_RS18380	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_RS18385	COG2364	Membrane
EXW36_RS18395	COG0346	lactoylglutathione lyase activity
EXW36_RS18400	COG5001	Diguanylate cyclase
EXW36_RS18400	COG3300	MHYT domain
EXW36_RS18440	COG1346	cytolysis
EXW36_RS18450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW36_RS18455	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_RS18455	COG0596	Alpha beta hydrolase
EXW36_RS18460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW36_RS18470	COG2188	Transcriptional regulator
EXW36_RS18475	COG2723	6-phospho-beta-galactosidase activity
EXW36_RS18480	COG0823	Involved in the tonB-independent uptake of proteins
EXW36_RS18485	COG3773	Cell wall hydrolase
EXW36_RS18500	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW36_RS18510	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW36_RS18515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW36_RS18520	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW36_RS18530	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW36_RS18535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW36_RS18540	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW36_RS18545	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW36_RS18545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW36_RS18555	COG2359	stage V sporulation protein S
EXW36_RS18560	COG1692	metallophosphoesterase
EXW36_RS18565	COG1418	mRNA catabolic process
EXW36_RS18570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW36_RS18575	COG1546	Belongs to the CinA family
EXW36_RS18575	COG1058	Belongs to the CinA family
EXW36_RS18580	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW36_RS18585	COG1426	Protein conserved in bacteria
EXW36_RS18600	COG0300	oxidoreductase activity
EXW36_RS18605	COG0612	Peptidase, M16
EXW36_RS18610	COG0612	Peptidase, M16
EXW36_RS18615	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW36_RS18620	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW36_RS18625	COG3845	ABC transporter
EXW36_RS18630	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW36_RS18635	COG2188	Transcriptional regulator
EXW36_RS18645	COG1674	ftsk spoiiie
EXW36_RS18655	COG0740	serine-type endopeptidase activity
EXW36_RS18660	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW36_RS18670	COG0527	aspartate kinase activity
EXW36_RS18675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW36_RS18680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW36_RS18685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW36_RS18690	COG1873	PFAM PRC-barrel domain
EXW36_RS18695	COG0612	Peptidase, M16
EXW36_RS18700	COG0726	polysaccharide deacetylase
EXW36_RS18705	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW36_RS18715	COG0196	riboflavin kinase activity
EXW36_RS18725	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW36_RS18730	COG1550	Protein conserved in bacteria
EXW36_RS18735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW36_RS18740	COG1358	cellular component organization or biogenesis
EXW36_RS18745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW36_RS18750	COG0195	Participates in both transcription termination and antitermination
EXW36_RS18755	COG0779	Required for maturation of 30S ribosomal subunits
EXW36_RS18765	COG0442	prolyl-tRNA aminoacylation
EXW36_RS18770	COG0750	zinc metalloprotease
EXW36_RS18780	COG4589	Belongs to the CDS family
EXW36_RS18790	COG0233	cytoplasmic translational termination
EXW36_RS18795	COG0528	UMP kinase activity
EXW36_RS18800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW36_RS18810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW36_RS18815	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW36_RS18820	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW36_RS18825	COG4974	Belongs to the 'phage' integrase family
EXW36_RS18830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW36_RS18835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_RS18840	COG0758	DNA mediated transformation
EXW36_RS18845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW36_RS18850	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW36_RS18855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW36_RS18870	COG0335	large ribosomal subunit rRNA binding
EXW36_RS18875	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW36_RS18880	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW36_RS18885	COG1837	Belongs to the UPF0109 family
EXW36_RS18895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW36_RS18905	COG0552	protein localization to endoplasmic reticulum
EXW36_RS18910	COG1196	nuclear chromosome segregation
EXW36_RS18915	COG0571	ribonuclease III activity
EXW36_RS18920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW36_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS18930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW36_RS18935	COG0416	fatty acid biosynthetic process
EXW36_RS18940	COG2050	protein possibly involved in aromatic compounds catabolism
EXW36_RS18940	COG1349	DNA-binding transcription factor activity
EXW36_RS18945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW36_RS18950	COG1461	Dihydroxyacetone kinase
EXW36_RS18955	COG1302	Protein conserved in bacteria
EXW36_RS18970	COG1564	THIamine pyrophosphokinase
EXW36_RS18975	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW36_RS18985	COG2815	serine threonine protein kinase
EXW36_RS18985	COG0515	serine threonine protein kinase
EXW36_RS18990	COG0631	protein serine/threonine phosphatase activity
EXW36_RS18995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW36_RS19000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW36_RS19000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW36_RS19005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW36_RS19010	COG0242	peptide deformylase activity
EXW36_RS19015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW36_RS19020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW36_RS19025	COG1758	RNA polymerase activity
EXW36_RS19040	COG1561	YicC-like family, N-terminal region
EXW36_RS19045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW36_RS19055	COG0006	proline dipeptidase activity
EXW36_RS19075	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW36_RS19100	COG0167	dihydroorotate dehydrogenase activity
EXW36_RS19105	COG0543	2 iron, 2 sulfur cluster binding
EXW36_RS19110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW36_RS19120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW36_RS19125	COG0540	Belongs to the ATCase OTCase family
EXW36_RS19135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW36_RS19140	COG0564	pseudouridine synthase activity
EXW36_RS19145	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW36_RS19155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW36_RS19160	COG3599	regulation of cell shape
EXW36_RS19165	COG2302	S4 RNA-binding domain
EXW36_RS19170	COG0762	integral membrane protein
EXW36_RS19175	COG1799	cell septum assembly
EXW36_RS19180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW36_RS19190	COG1873	PFAM PRC-barrel domain
EXW36_RS19195	COG1191	sigma factor activity
EXW36_RS19200	COG1191	sigma factor activity
EXW36_RS19210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW36_RS19215	COG0849	cell division
EXW36_RS19220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW36_RS19235	COG0772	Belongs to the SEDS family
EXW36_RS19240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW36_RS19245	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW36_RS19250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW36_RS19255	COG0768	penicillin binding
EXW36_RS19260	COG0768	penicillin binding
EXW36_RS19270	COG0275	rRNA processing
EXW36_RS19275	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW36_RS19280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW36_RS19285	COG0454	-acetyltransferase
EXW36_RS19295	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW36_RS19300	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW36_RS19305	COG1323	Belongs to the UPF0348 family
EXW36_RS19310	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW36_RS19315	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW36_RS19320	COG3314	Sporulation integral membrane protein YlbJ
EXW36_RS19330	COG0742	ribosomal rna small subunit methyltransferase
EXW36_RS19340	COG4471	UPF0298 protein
EXW36_RS19345	COG3679	Belongs to the UPF0342 family
EXW36_RS19350	COG0406	alpha-ribazole phosphatase activity
EXW36_RS19365	COG2340	Cysteine-rich secretory protein family
EXW36_RS19375	COG3336	cytochrome c oxidase
EXW36_RS19400	COG0109	protoheme IX farnesyltransferase activity
EXW36_RS19405	COG1612	heme a metabolic process
EXW36_RS19410	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW36_RS19415	COG0772	Belongs to the SEDS family
EXW36_RS19420	COG4838	Belongs to the UPF0358 family
EXW36_RS19425	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW36_RS19430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW36_RS19440	COG4896	Protein conserved in bacteria
EXW36_RS19455	COG1217	gtp-binding protein TYPA
EXW36_RS19465	COG0483	inositol monophosphate 1-phosphatase activity
EXW36_RS19475	COG4493	Belongs to the UPF0637 family
EXW36_RS19480	COG4476	Belongs to the UPF0223 family
EXW36_RS19485	COG1982	Orn Lys Arg decarboxylase major
EXW36_RS19530	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_RS19535	COG0022	dehydrogenase e1 component
EXW36_RS19540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_RS19555	COG0561	phosphatase activity
EXW36_RS19560	COG5503	Protein of unknown function (DUF1447)
EXW36_RS19565	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW36_RS19570	COG0569	domain protein
EXW36_RS19580	COG1473	amidohydrolase
EXW36_RS19585	COG2171	N-acyltransferase activity
EXW36_RS19590	COG0583	DNA-binding transcription factor activity
EXW36_RS19595	COG0517	IMP dehydrogenase activity
EXW36_RS19605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW36_RS19615	COG4703	Protein of unknown function (DUF1797)
EXW36_RS19630	COG2200	EAL domain
EXW36_RS19635	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS19640	COG1408	metallophosphoesterase
EXW36_RS19685	COG2814	Major facilitator Superfamily
EXW36_RS19695	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW36_RS19705	COG3209	COG3209 Rhs family protein
EXW36_RS19715	COG2205	protein histidine kinase activity
EXW36_RS19725	COG0436	Aminotransferase
EXW36_RS19730	COG1609	Transcriptional regulator
EXW36_RS19735	COG3833	ABC-type maltose transport systems, permease component
EXW36_RS19740	COG1175	transmembrane transport
EXW36_RS19745	COG2182	Extracellular solute-binding protein
EXW36_RS19755	COG0366	Alpha amylase catalytic
EXW36_RS19760	COG3842	ATPase activity
EXW36_RS19800	COG0183	Belongs to the thiolase family
EXW36_RS19835	COG1695	Transcriptional regulator
EXW36_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS19850	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW36_RS19855	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW36_RS19860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW36_RS19865	COG0436	Aminotransferase
EXW36_RS19870	COG1850	ribulose-bisphosphate carboxylase activity
EXW36_RS19875	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW36_RS19880	COG0235	Class ii aldolase
EXW36_RS19885	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW36_RS19900	COG2084	Dehydrogenase
EXW36_RS19910	COG2199	diguanylate cyclase activity
EXW36_RS19915	COG0778	Nitroreductase
EXW36_RS19940	COG1263	PTS System
EXW36_RS19940	COG2190	(PTS) system
EXW36_RS19940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW36_RS19945	COG3711	transcriptional antiterminator
EXW36_RS19955	COG2188	Transcriptional regulator
EXW36_RS19960	COG0363	glucosamine-6-phosphate deaminase activity
EXW36_RS19965	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW36_RS19975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW36_RS19980	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW36_RS19990	COG1547	Domain of unknown function (DUF309)
EXW36_RS20000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW36_RS20005	COG4086	secreted protein
EXW36_RS20010	COG0561	phosphatase activity
EXW36_RS20015	COG0697	spore germination
EXW36_RS20030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_RS20055	COG0733	neurotransmitter:sodium symporter activity
EXW36_RS20075	COG1686	Belongs to the peptidase S11 family
EXW36_RS20080	COG1725	Transcriptional regulator
EXW36_RS20085	COG1131	(ABC) transporter
EXW36_RS20110	COG1846	Transcriptional regulator
EXW36_RS20125	COG0598	Magnesium transport protein CorA
EXW36_RS20140	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW36_RS20150	COG4974	Belongs to the 'phage' integrase family
EXW36_RS20160	COG0735	belongs to the Fur family
EXW36_RS20165	COG1300	Membrane
EXW36_RS20185	COG0667	Aldo Keto reductase
EXW36_RS20190	COG0656	L-ascorbic acid biosynthetic process
EXW36_RS20195	COG0456	acetyltransferase
EXW36_RS20195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW36_RS20205	COG1525	nuclease
EXW36_RS20205	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS20205	COG4085	toxin activity
EXW36_RS20210	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW36_RS20220	COG0596	Alpha beta hydrolase
EXW36_RS20225	COG2056	Na+-H+ antiporter family
EXW36_RS20230	COG1609	Transcriptional regulator
EXW36_RS20235	COG0456	acetyltransferase
EXW36_RS20240	COG1073	alpha beta
EXW36_RS20255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW36_RS20255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW36_RS20260	COG0307	riboflavin synthase, alpha
EXW36_RS20265	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW36_RS20265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW36_RS20280	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW36_RS20285	COG4106	trans-aconitate 2-methyltransferase activity
EXW36_RS20290	COG1073	alpha beta
EXW36_RS20290	COG2226	methyltransferase
EXW36_RS20295	COG0156	8-amino-7-oxononanoate synthase activity
EXW36_RS20305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW36_RS20315	COG1757	Na H antiporter
EXW36_RS20320	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS20330	COG1522	sequence-specific DNA binding
EXW36_RS20365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW36_RS20375	COG0300	oxidoreductase activity
EXW36_RS20380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS20385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_RS20390	COG1760	l-serine dehydratase
EXW36_RS20395	COG1760	l-serine dehydratase
EXW36_RS20405	COG1234	tRNA 3'-trailer cleavage
EXW36_RS20420	COG1285	pathogenesis
EXW36_RS20435	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW36_RS20440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS20455	COG1376	ErfK ybiS ycfS ynhG family protein
EXW36_RS20460	COG4129	membrane
EXW36_RS20465	COG1126	abc transporter atp-binding protein
EXW36_RS20470	COG0765	amino acid transport
EXW36_RS20475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW36_RS20490	COG2816	NAD+ diphosphatase activity
EXW36_RS20495	COG2323	membrane
EXW36_RS20500	COG0772	Belongs to the SEDS family
EXW36_RS20505	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW36_RS20510	COG0022	dehydrogenase e1 component
EXW36_RS20515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW36_RS20520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW36_RS20525	COG3426	butyrate kinase activity
EXW36_RS20535	COG0280	phosphate acetyltransferase
EXW36_RS20540	COG3290	protein histidine kinase activity
EXW36_RS20540	COG3829	transcription factor binding
EXW36_RS20550	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_RS20555	COG3093	addiction module antidote protein HigA
EXW36_RS20595	COG0745	RESPONSE REGULATOR receiver
EXW36_RS20600	COG0750	zinc metalloprotease
EXW36_RS20605	COG0497	DNA recombination
EXW36_RS20610	COG1438	arginine binding
EXW36_RS20615	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW36_RS20620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW36_RS20625	COG0142	geranyltranstransferase activity
EXW36_RS20630	COG1722	exodeoxyribonuclease VII activity
EXW36_RS20635	COG1570	exodeoxyribonuclease VII activity
EXW36_RS20640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW36_RS20645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW36_RS20650	COG1302	Protein conserved in bacteria
EXW36_RS20655	COG0439	Biotin carboxylase
EXW36_RS20660	COG0511	ligase activity, forming carbon-carbon bonds
EXW36_RS20705	COG3854	ATPases associated with a variety of cellular activities
EXW36_RS20725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW36_RS20730	COG0006	proline dipeptidase activity
EXW36_RS20735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW36_RS20745	COG3872	metal-dependent enzyme
EXW36_RS20755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW36_RS20790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS20800	COG1609	Transcriptional regulator
EXW36_RS20810	COG2076	Multidrug Resistance protein
EXW36_RS20815	COG2076	Multidrug Resistance protein
EXW36_RS20850	COG1725	Transcriptional regulator
EXW36_RS20865	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW36_RS20870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW36_RS20875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW36_RS20880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_RS20905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW36_RS20930	COG4970	Tfp pilus assembly protein FimT
EXW36_RS20940	COG1459	type II secretion system
EXW36_RS20945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW36_RS21000	COG1410	methionine synthase
EXW36_RS21000	COG0646	methionine synthase
EXW36_RS21005	COG0646	methionine synthase
EXW36_RS21005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW36_RS21010	COG0626	cystathionine gamma-synthase activity
EXW36_RS21015	COG0626	cystathionine gamma-synthase activity
EXW36_RS21030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS21040	COG1940	carbohydrate kinase activity
EXW36_RS21045	COG4483	Protein conserved in bacteria
EXW36_RS21050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW36_RS21055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW36_RS21060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW36_RS21065	COG0704	Plays a role in the regulation of phosphate uptake
EXW36_RS21075	COG0581	inorganic phosphate transmembrane transporter activity
EXW36_RS21080	COG0573	inorganic phosphate transmembrane transporter activity
EXW36_RS21085	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW36_RS21090	COG0768	penicillin binding
EXW36_RS21095	COG0477	Major facilitator Superfamily
EXW36_RS21100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_RS21120	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW36_RS21125	COG0735	belongs to the Fur family
EXW36_RS21130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW36_RS21135	COG1121	(ABC) transporter
EXW36_RS21140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS21150	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW36_RS21165	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW36_RS21170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW36_RS21175	COG2384	SAM-dependent methyltransferase
EXW36_RS21180	COG2010	Cytochrome c
EXW36_RS21185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW36_RS21190	COG0358	DNA primase activity
EXW36_RS21200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW36_RS21205	COG0517	IMP dehydrogenase activity
EXW36_RS21210	COG1381	Involved in DNA repair and RecF pathway recombination
EXW36_RS21220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW36_RS21225	COG0295	cytidine deaminase activity
EXW36_RS21230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW36_RS21235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW36_RS21240	COG1480	7TM receptor with intracellular HD hydrolase
EXW36_RS21245	COG1702	phosphate starvation-inducible protein PhoH
EXW36_RS21260	COG1610	YqeY-like protein
EXW36_RS21265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW36_RS21270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW36_RS21275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW36_RS21285	COG0484	heat shock protein binding
EXW36_RS21290	COG0443	Heat shock 70 kDa protein
EXW36_RS21300	COG1420	regulation of RNA biosynthetic process
EXW36_RS21305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW36_RS21310	COG1733	regulation of RNA biosynthetic process
EXW36_RS21315	COG0481	GTPase activity
EXW36_RS21325	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW36_RS21330	COG0268	Binds directly to 16S ribosomal RNA
EXW36_RS21335	COG1466	dna polymerase III delta subunit
EXW36_RS21345	COG2333	competence protein COMEC
EXW36_RS21345	COG0658	competence protein
EXW36_RS21350	COG2131	deaminase
EXW36_RS21355	COG1596	polysaccharide export
EXW36_RS21355	COG1555	photosystem II stabilization
EXW36_RS21360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW36_RS21365	COG2226	methyltransferase
EXW36_RS21370	COG0799	negative regulation of ribosome biogenesis
EXW36_RS21375	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW36_RS21380	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW36_RS21385	COG1534	Rna-binding protein
EXW36_RS21390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW36_RS21395	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW36_RS21400	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW36_RS21410	COG0688	phosphatidylethanolamine metabolic process
EXW36_RS21420	COG1595	DNA-templated transcription, initiation
EXW36_RS21425	COG2357	RelA SpoT domain protein
EXW36_RS21435	COG1785	Belongs to the alkaline phosphatase family
EXW36_RS21445	COG2267	carboxylic ester hydrolase activity
EXW36_RS21485	COG3186	Phenylalanine-4-hydroxylase
EXW36_RS21490	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW36_RS21495	COG2514	catechol 2,3-dioxygenase activity
EXW36_RS21500	COG2259	Doxx family
EXW36_RS21540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS21550	COG1454	alcohol dehydrogenase
EXW36_RS21550	COG1012	belongs to the aldehyde dehydrogenase family
EXW36_RS21555	COG0626	cystathionine gamma-synthase activity
EXW36_RS21560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW36_RS21565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW36_RS21570	COG2226	methyltransferase
EXW36_RS21585	COG0768	penicillin binding
EXW36_RS21590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW36_RS21595	COG0572	uridine kinase
EXW36_RS21600	COG0826	peptidase U32
EXW36_RS21605	COG0826	peptidase U32
EXW36_RS21610	COG4122	O-methyltransferase activity
EXW36_RS21615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW36_RS21625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW36_RS21630	COG4472	Bacterial protein of unknown function (DUF965)
EXW36_RS21635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW36_RS21645	COG0628	permease
EXW36_RS21665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW36_RS21675	COG0482	sulfurtransferase activity
EXW36_RS21680	COG1104	cysteine desulfurase activity
EXW36_RS21685	COG1959	2 iron, 2 sulfur cluster binding
EXW36_RS21690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW36_RS21700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW36_RS21705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW36_RS21720	COG1490	D-aminoacyl-tRNA deacylase activity
EXW36_RS21725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW36_RS21730	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW36_RS21735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW36_RS21735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW36_RS21740	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_RS21745	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW36_RS21745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW36_RS21755	COG2244	polysaccharide biosynthetic process
EXW36_RS21760	COG2323	membrane
EXW36_RS21770	COG1862	Preprotein translocase
EXW36_RS21775	COG0343	queuine tRNA-ribosyltransferase activity
EXW36_RS21780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW36_RS21790	COG2255	four-way junction helicase activity
EXW36_RS21795	COG0632	four-way junction helicase activity
EXW36_RS21800	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW36_RS21825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW36_RS21830	COG0157	Belongs to the NadC ModD family
EXW36_RS21835	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW36_RS21840	COG1104	cysteine desulfurase activity
EXW36_RS21845	COG1827	regulation of RNA biosynthetic process
EXW36_RS21850	COG2258	MOSC domain
EXW36_RS21855	COG0077	Prephenate dehydratase
EXW36_RS21860	COG0577	efflux transmembrane transporter activity
EXW36_RS21865	COG0577	efflux transmembrane transporter activity
EXW36_RS21870	COG1136	(ABC) transporter
EXW36_RS21875	COG5002	protein histidine kinase activity
EXW36_RS21880	COG0745	RESPONSE REGULATOR receiver
EXW36_RS21885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW36_RS21890	COG3290	protein histidine kinase activity
EXW36_RS21900	COG2868	ribosomal protein
EXW36_RS21910	COG1530	ribonuclease E activity
EXW36_RS21915	COG1994	Peptidase M50
EXW36_RS21920	COG0739	heme binding
EXW36_RS21925	COG2894	cell division
EXW36_RS21930	COG0850	regulation of cytokinetic process
EXW36_RS21945	COG1077	Cell shape determining protein MreB Mrl
EXW36_RS21950	COG2003	Belongs to the UPF0758 family
EXW36_RS21955	COG0424	maF-like protein
EXW36_RS21965	COG0285	dihydrofolate synthase activity
EXW36_RS21980	COG1388	LysM domain
EXW36_RS21985	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW36_RS21990	COG0113	porphobilinogen synthase activity
EXW36_RS21995	COG1587	Uroporphyrinogen-III synthase
EXW36_RS22000	COG0181	hydroxymethylbilane synthase activity
EXW36_RS22005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW36_RS22010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW36_RS22015	COG1846	Transcriptional regulator
EXW36_RS22020	COG1764	response to oxidative stress
EXW36_RS22025	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW36_RS22035	COG0470	DNA polymerase III
EXW36_RS22035	COG1067	ATP-dependent peptidase activity
EXW36_RS22045	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW36_RS22075	COG0622	Phosphoesterase
EXW36_RS22085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW36_RS22090	COG5401	PFAM Sporulation and spore germination
EXW36_RS22100	COG0477	Major facilitator Superfamily
EXW36_RS22105	COG2197	response regulator
EXW36_RS22110	COG2233	PERMEase
EXW36_RS22115	COG0402	S-adenosylhomocysteine deaminase activity
EXW36_RS22120	COG1983	PspC domain protein
EXW36_RS22125	COG1396	sequence-specific DNA binding
EXW36_RS22130	COG0697	spore germination
EXW36_RS22140	COG1959	2 iron, 2 sulfur cluster binding
EXW36_RS22145	COG1668	transmembrane transport
EXW36_RS22150	COG4152	abc transporter atp-binding protein
EXW36_RS22155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW36_RS22160	COG1360	Flagellar Motor Protein
EXW36_RS22165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW36_RS22170	COG1876	peptidase activity
EXW36_RS22175	COG0824	Thioesterase
EXW36_RS22180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW36_RS22185	COG1053	succinate dehydrogenase
EXW36_RS22190	COG2009	succinate dehydrogenase
EXW36_RS22195	COG1719	4-vinyl reductase, 4VR
EXW36_RS22200	COG0322	excinuclease ABC activity
EXW36_RS22205	COG3118	belongs to the thioredoxin family
EXW36_RS22210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW36_RS22215	COG2086	electron transfer activity
EXW36_RS22220	COG1024	Enoyl-CoA hydratase
EXW36_RS22225	COG1309	transcriptional regulator
EXW36_RS22230	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS22250	COG2318	DinB family
EXW36_RS22275	COG1131	(ABC) transporter
EXW36_RS22280	COG2205	protein histidine kinase activity
EXW36_RS22285	COG0745	RESPONSE REGULATOR receiver
EXW36_RS22295	COG4895	conserved protein (DUF2196)
EXW36_RS22300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW36_RS22310	COG4509	Sortase family
EXW36_RS22315	COG1120	ATPase activity
EXW36_RS22330	COG5386	Cell surface protein
EXW36_RS22340	COG5386	Cell surface protein
EXW36_RS22345	COG1114	Component of the transport system for branched-chain amino acids
EXW36_RS22355	COG1193	negative regulation of DNA recombination
EXW36_RS22360	COG1796	DNA polymerase
EXW36_RS22360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW36_RS22365	COG1286	toxin biosynthetic process
EXW36_RS22370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW36_RS22375	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW36_RS22400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW36_RS22405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW36_RS22415	COG1418	mRNA catabolic process
EXW36_RS22445	COG2814	Major facilitator Superfamily
EXW36_RS22450	COG1566	PFAM secretion protein HlyD family protein
EXW36_RS22455	COG1309	transcriptional regulator
EXW36_RS22460	COG1363	Peptidase, m42
EXW36_RS22470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW36_RS22485	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW36_RS22495	COG1484	DNA-dependent DNA replication
EXW36_RS22500	COG3611	Membrane attachment protein
EXW36_RS22505	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW36_RS22510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW36_RS22515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW36_RS22520	COG0237	dephospho-CoA kinase activity
EXW36_RS22525	COG1971	Probably functions as a manganese efflux pump
EXW36_RS22535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_RS22535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_RS22540	COG5002	protein histidine kinase activity
EXW36_RS22545	COG0745	RESPONSE REGULATOR receiver
EXW36_RS22560	COG0039	L-malate dehydrogenase activity
EXW36_RS22565	COG0538	isocitrate dehydrogenase activity
EXW36_RS22570	COG0372	Belongs to the citrate synthase family
EXW36_RS22580	COG0628	permease
EXW36_RS22585	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW36_RS22595	COG0205	6-phosphofructokinase activity
EXW36_RS22605	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW36_RS22610	COG1725	Transcriptional regulator
EXW36_RS22615	COG0281	malic enzyme
EXW36_RS22620	COG0587	DNA-directed DNA polymerase activity
EXW36_RS22635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW36_RS22650	COG4109	DRTGG domain
EXW36_RS22665	COG0006	proline dipeptidase activity
EXW36_RS22695	COG0662	Cupin 2, conserved barrel domain protein
EXW36_RS22705	COG1476	TRANSCRIPTIONal
EXW36_RS22720	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS22725	COG0589	response to stress
EXW36_RS22745	COG0165	Argininosuccinate lyase
EXW36_RS22750	COG0137	argininosuccinate synthase activity
EXW36_RS22765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS22785	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW36_RS22790	COG0827	DNA restriction-modification system
EXW36_RS22795	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW36_RS22800	COG3874	Sporulation protein YtfJ
EXW36_RS22815	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW36_RS22825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_RS22840	COG1104	cysteine desulfurase activity
EXW36_RS22845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW36_RS22860	COG1309	transcriptional regulator
EXW36_RS22865	COG1956	GAF domain-containing protein
EXW36_RS22870	COG0626	cystathionine gamma-synthase activity
EXW36_RS22875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW36_RS22900	COG1595	DNA-templated transcription, initiation
EXW36_RS22910	COG0110	maltose O-acetyltransferase activity
EXW36_RS22915	COG0456	acetyltransferase
EXW36_RS22920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW36_RS22925	COG0454	-acetyltransferase
EXW36_RS22930	COG0517	IMP dehydrogenase activity
EXW36_RS22935	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW36_RS22940	COG2267	carboxylic ester hydrolase activity
EXW36_RS22950	COG0745	RESPONSE REGULATOR receiver
EXW36_RS22955	COG5002	protein histidine kinase activity
EXW36_RS22960	COG0666	response to abiotic stimulus
EXW36_RS22970	COG1970	mechanosensitive ion channel activity
EXW36_RS22990	COG1609	Transcriptional regulator
EXW36_RS23005	COG4851	CamS sex pheromone cAM373 precursor
EXW36_RS23010	COG3118	belongs to the thioredoxin family
EXW36_RS23020	COG2309	aminopeptidase activity
EXW36_RS23050	COG0697	spore germination
EXW36_RS23055	COG0789	Transcriptional regulator
EXW36_RS23060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW36_RS23070	COG1674	ftsk spoiiie
EXW36_RS23085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_RS23090	COG4848	Belongs to the UPF0354 family
EXW36_RS23095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS23100	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW36_RS23105	COG1363	Peptidase, m42
EXW36_RS23115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS23120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW36_RS23130	COG0510	thiamine kinase activity
EXW36_RS23135	COG1523	belongs to the glycosyl hydrolase 13 family
EXW36_RS23145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW36_RS23150	COG1349	DNA-binding transcription factor activity
EXW36_RS23155	COG1187	pseudouridine synthase activity
EXW36_RS23160	COG2244	polysaccharide biosynthetic process
EXW36_RS23165	COG2081	HI0933 family
EXW36_RS23170	COG2814	Major facilitator Superfamily
EXW36_RS23180	COG3832	glyoxalase III activity
EXW36_RS23200	COG1329	Transcriptional regulator
EXW36_RS23225	COG0314	molybdopterin synthase activity
EXW36_RS23230	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW36_RS23235	COG0303	'Molybdopterin
EXW36_RS23240	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW36_RS23245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW36_RS23250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW36_RS23270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW36_RS23280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW36_RS23320	COG0495	leucyl-tRNA aminoacylation
EXW36_RS23325	COG2814	Major facilitator Superfamily
EXW36_RS23330	COG0475	glutathione-regulated potassium exporter activity
EXW36_RS23335	COG0490	domain, Protein
EXW36_RS23340	COG0582	viral genome integration into host DNA
EXW36_RS23350	COG1136	(ABC) transporter
EXW36_RS23365	COG1242	4 iron, 4 sulfur cluster binding
EXW36_RS23370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW36_RS23375	COG1131	(ABC) transporter
EXW36_RS23385	COG1794	racemase activity, acting on amino acids and derivatives
EXW36_RS23400	COG2267	carboxylic ester hydrolase activity
EXW36_RS23405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW36_RS23410	COG0671	phosphoesterase, PA-phosphatase related
EXW36_RS23415	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS23430	COG0746	molybdenum cofactor guanylyltransferase activity
EXW36_RS23450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW36_RS23455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW36_RS23495	COG5002	protein histidine kinase activity
EXW36_RS23500	COG3852	Histidine kinase
EXW36_RS23505	COG0753	catalase activity
EXW36_RS23510	COG2267	carboxylic ester hydrolase activity
EXW36_RS23520	COG1368	sulfuric ester hydrolase activity
EXW36_RS23530	COG4895	conserved protein (DUF2196)
EXW36_RS23545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW36_RS23550	COG1116	anion transmembrane transporter activity
EXW36_RS23555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW36_RS23580	COG0494	nUDIX hydrolase
EXW36_RS23615	COG2076	Multidrug Resistance protein
EXW36_RS23620	COG2076	Multidrug Resistance protein
EXW36_RS23625	COG0789	Transcriptional regulator
EXW36_RS23630	COG1854	S-ribosylhomocysteine lyase activity
EXW36_RS23640	COG0288	reversible hydration of carbon dioxide
EXW36_RS23645	COG1271	oxidase subunit
EXW36_RS23650	COG1294	oxidase, subunit
EXW36_RS23670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS23695	COG1842	Phage shock protein A
EXW36_RS23720	COG3859	Proton-coupled thiamine transporter YuaJ
EXW36_RS23725	COG5002	protein histidine kinase activity
EXW36_RS23730	COG0745	RESPONSE REGULATOR receiver
EXW36_RS23755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW36_RS23760	COG1597	lipid kinase activity
EXW36_RS23790	COG1136	(ABC) transporter
EXW36_RS23820	COG5002	protein histidine kinase activity
EXW36_RS23830	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS23845	COG0577	efflux transmembrane transporter activity
EXW36_RS23850	COG1136	(ABC) transporter
EXW36_RS23855	COG2207	Transcriptional regulator
EXW36_RS23855	COG3708	Transcriptional regulator
EXW36_RS23865	COG1131	(ABC) transporter
EXW36_RS23875	COG5658	integral membrane protein
EXW36_RS23880	COG0640	Transcriptional regulator
EXW36_RS23885	COG0745	RESPONSE REGULATOR receiver
EXW36_RS23890	COG2205	protein histidine kinase activity
EXW36_RS23895	COG0577	efflux transmembrane transporter activity
EXW36_RS23900	COG0577	efflux transmembrane transporter activity
EXW36_RS23905	COG1136	(ABC) transporter
EXW36_RS23910	COG0577	efflux transmembrane transporter activity
EXW36_RS23925	COG2188	Transcriptional regulator
EXW36_RS23945	COG3964	amidohydrolase
EXW36_RS23965	COG4948	Mandelate Racemase Muconate Lactonizing
EXW36_RS23970	COG0318	PFAM AMP-dependent synthetase and ligase
EXW36_RS23980	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW36_RS23990	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW36_RS23995	COG1169	isochorismate synthase
EXW36_RS24000	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW36_RS24005	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW36_RS24010	COG1278	Cold shock
EXW36_RS24020	COG0789	Transcriptional regulator
EXW36_RS24030	COG0058	SHG alpha-glucan phosphorylase activity
EXW36_RS24040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW36_RS24045	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW36_RS24050	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW36_RS24200	COG1285	pathogenesis
EXW36_RS24205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW36_RS24215	COG0166	Belongs to the GPI family
EXW36_RS24220	COG2155	Conserved Protein
EXW36_RS24225	COG1098	S1 RNA binding domain
EXW36_RS24230	COG0436	Aminotransferase
EXW36_RS24235	COG1522	sequence-specific DNA binding
EXW36_RS24240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW36_RS24245	COG2267	carboxylic ester hydrolase activity
EXW36_RS24255	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW36_RS24275	COG5018	Exonuclease
EXW36_RS24280	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_RS24300	COG2050	protein possibly involved in aromatic compounds catabolism
EXW36_RS24310	COG1268	BioY protein
EXW36_RS24315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_RS24320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW36_RS24330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW36_RS24335	COG3584	3D domain protein
EXW36_RS24350	COG1252	NADH dehydrogenase
EXW36_RS24355	COG0492	ferredoxin-NADP+ reductase activity
EXW36_RS24360	COG3708	Transcriptional regulator
EXW36_RS24375	COG1683	Conserved Protein
EXW36_RS24395	COG0316	Belongs to the HesB IscA family
EXW36_RS24400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW36_RS24405	COG4844	belongs to the
EXW36_RS24410	COG1252	NADH dehydrogenase
EXW36_RS24420	COG0390	transport system, permease component
EXW36_RS24425	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW36_RS24455	COG4837	Protein of unknown function (DUF1462)
EXW36_RS24460	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW36_RS24470	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_RS24475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW36_RS24490	COG0577	efflux transmembrane transporter activity
EXW36_RS24490	COG1136	(ABC) transporter
EXW36_RS24495	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW36_RS24505	COG0647	UMP catabolic process
EXW36_RS24515	COG2445	Protein of unknown function DUF86
EXW36_RS24520	COG1494	fructose-1,6-bisphosphatase
EXW36_RS24535	COG4470	Protein conserved in bacteria
EXW36_RS24545	COG0789	Transcriptional regulator
EXW36_RS24550	COG4377	Putative membrane peptidase family (DUF2324)
EXW36_RS24570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW36_RS24575	COG0739	heme binding
EXW36_RS24585	COG3377	Domain of unknown function (DUF1805)
EXW36_RS24590	COG0737	Belongs to the 5'-nucleotidase family
EXW36_RS24595	COG1695	Transcriptional regulator
EXW36_RS24605	COG0719	Fe-S assembly protein
EXW36_RS24610	COG0822	iron-sulfur transferase activity
EXW36_RS24615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW36_RS24620	COG0719	Fe-S assembly protein
EXW36_RS24625	COG0396	ATPase activity
EXW36_RS24630	COG1464	Belongs to the NlpA lipoprotein family
EXW36_RS24635	COG1464	Belongs to the NlpA lipoprotein family
EXW36_RS24640	COG2011	ABC-type metal ion transport system permease component
EXW36_RS24645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW36_RS24655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS24660	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW36_RS24665	COG0509	glycine decarboxylation via glycine cleavage system
EXW36_RS24670	COG1393	Belongs to the ArsC family
EXW36_RS24710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS24725	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS24730	COG0183	Belongs to the thiolase family
EXW36_RS24735	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW36_RS24735	COG1024	Enoyl-CoA hydratase
EXW36_RS24745	COG1686	Belongs to the peptidase S11 family
EXW36_RS24750	COG0506	proline dehydrogenase activity
EXW36_RS24760	COG0011	TIGRFAM Protein of
EXW36_RS24765	COG0840	transmembrane signaling receptor activity
EXW36_RS24780	COG2814	Major facilitator Superfamily
EXW36_RS24785	COG0531	amino acid
EXW36_RS24810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW36_RS24840	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS24850	COG1376	ErfK ybiS ycfS ynhG family protein
EXW36_RS24855	COG0745	RESPONSE REGULATOR receiver
EXW36_RS24860	COG5002	protein histidine kinase activity
EXW36_RS24870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW36_RS24880	COG0840	transmembrane signaling receptor activity
EXW36_RS24885	COG0840	transmembrane signaling receptor activity
EXW36_RS24890	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW36_RS24895	COG3227	Zinc metalloprotease (Elastase)
EXW36_RS24900	COG1741	Belongs to the pirin family
EXW36_RS24915	COG0586	Pfam SNARE associated Golgi protein
EXW36_RS24920	COG0475	glutathione-regulated potassium exporter activity
EXW36_RS24925	COG0490	domain, Protein
EXW36_RS24930	COG1115	amino acid carrier protein
EXW36_RS24935	COG0783	Belongs to the Dps family
EXW36_RS24945	COG2318	DinB family
EXW36_RS24955	COG1611	Belongs to the LOG family
EXW36_RS24965	COG1528	Iron-storage protein
EXW36_RS24975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS24980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS24985	COG1115	amino acid carrier protein
EXW36_RS24990	COG1115	amino acid carrier protein
EXW36_RS24995	COG2910	NAD(P)H-binding
EXW36_RS25005	COG0656	L-ascorbic acid biosynthetic process
EXW36_RS25010	COG2814	Major facilitator Superfamily
EXW36_RS25015	COG1733	regulation of RNA biosynthetic process
EXW36_RS25025	COG1252	NADH dehydrogenase
EXW36_RS25045	COG0840	transmembrane signaling receptor activity
EXW36_RS25045	COG3290	protein histidine kinase activity
EXW36_RS25055	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW36_RS25075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW36_RS25090	COG4224	UPF0291 protein
EXW36_RS25095	COG1335	isochorismatase
EXW36_RS25100	COG1522	sequence-specific DNA binding
EXW36_RS25110	COG1522	sequence-specific DNA binding
EXW36_RS25115	COG0288	reversible hydration of carbon dioxide
EXW36_RS25120	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW36_RS25125	COG2233	PERMEase
EXW36_RS25150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS25170	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW36_RS25175	COG0557	exoribonuclease II activity
EXW36_RS25180	COG1647	Serine aminopeptidase, S33
EXW36_RS25185	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW36_RS25190	COG1346	cytolysis
EXW36_RS25205	COG0148	phosphopyruvate hydratase activity
EXW36_RS25215	COG0149	triose-phosphate isomerase activity
EXW36_RS25220	COG0126	phosphoglycerate kinase activity
EXW36_RS25225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW36_RS25240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW36_RS25275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW36_RS25290	COG2323	membrane
EXW36_RS25300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW36_RS25305	COG1481	regulation of sporulation
EXW36_RS25310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW36_RS25315	COG1660	Displays ATPase and GTPase activities
EXW36_RS25320	COG1051	belongs to the nudix hydrolase family
EXW36_RS25330	COG0492	ferredoxin-NADP+ reductase activity
EXW36_RS25335	COG0457	Tetratricopeptide repeat
EXW36_RS25340	COG0110	maltose O-acetyltransferase activity
EXW36_RS25345	COG0546	phosphoglycolate phosphatase activity
EXW36_RS25350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW36_RS25355	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW36_RS25360	COG1950	PFAM Membrane protein of
EXW36_RS25365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW36_RS25385	COG0789	Transcriptional regulator
EXW36_RS25420	COG0583	DNA-binding transcription factor activity
EXW36_RS25425	COG0789	Transcriptional regulator
EXW36_RS25430	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW36_RS25435	COG0488	(ABC) transporter
EXW36_RS25445	COG1132	(ABC) transporter
EXW36_RS25450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_RS25455	COG0793	Belongs to the peptidase S41A family
EXW36_RS25455	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_RS25460	COG2177	Part of the ABC transporter FtsEX involved in
EXW36_RS25465	COG2884	Cell division ATP-binding protein ftsE
EXW36_RS25490	COG1131	(ABC) transporter
EXW36_RS25525	COG1278	Cold shock
EXW36_RS25530	COG1040	competence protein
EXW36_RS25535	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW36_RS25540	COG0791	NLP P60 protein
EXW36_RS25540	COG1388	LysM domain
EXW36_RS25545	COG1733	regulation of RNA biosynthetic process
EXW36_RS25550	COG1307	EDD domain protein, DegV family
EXW36_RS25555	COG1739	Uncharacterized protein family UPF0029
EXW36_RS25560	COG1316	TRANSCRIPTIONal
EXW36_RS25565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW36_RS25570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_RS25575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW36_RS25585	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW36_RS25585	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW36_RS25605	COG1486	melibiose metabolic process
EXW36_RS25610	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_RS25615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_RS25635	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW36_RS25645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW36_RS25650	COG1301	dicarboxylic acid transport
EXW36_RS25665	COG1511	domain protein
EXW36_RS25670	COG0583	DNA-binding transcription factor activity
EXW36_RS25675	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW36_RS25685	COG1271	oxidase subunit
EXW36_RS25690	COG1294	oxidase, subunit
EXW36_RS25695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW36_RS25700	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW36_RS25705	COG1620	l-lactate permease
EXW36_RS25715	COG2389	metal-binding protein
EXW36_RS25725	COG1368	sulfuric ester hydrolase activity
EXW36_RS25735	COG1388	LysM domain
EXW36_RS25735	COG0791	NLP P60 protein
EXW36_RS25740	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW36_RS25750	COG1215	transferase activity, transferring glycosyl groups
EXW36_RS25755	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW36_RS25760	COG1388	LysM domain
EXW36_RS25760	COG3584	3D domain protein
EXW36_RS25775	COG4715	Zinc finger, swim domain protein
EXW36_RS25780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW36_RS25820	COG0577	efflux transmembrane transporter activity
EXW36_RS25825	COG1136	(ABC) transporter
EXW36_RS25855	COG5002	protein histidine kinase activity
EXW36_RS25855	COG3850	Histidine kinase
EXW36_RS25860	COG0745	RESPONSE REGULATOR receiver
EXW36_RS25865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW36_RS25875	COG1316	TRANSCRIPTIONal
EXW36_RS25880	COG3764	Sortase (surface protein transpeptidase)
EXW36_RS25915	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS25930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_RS25935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_RS25940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_RS25945	COG4464	protein tyrosine phosphatase activity
EXW36_RS25950	COG0489	protein tyrosine kinase activity
EXW36_RS25955	COG3944	biosynthesis protein
EXW36_RS25965	COG1132	(ABC) transporter
EXW36_RS25995	COG0367	asparagine synthase
EXW36_RS26000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW36_RS26010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW36_RS26020	COG1216	Glycosyl transferase, family 2
EXW36_RS26055	COG1215	transferase activity, transferring glycosyl groups
EXW36_RS26075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_RS26075	COG0463	Glycosyl transferase, family 2
EXW36_RS26085	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS26090	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS26095	COG1086	Polysaccharide biosynthesis protein
EXW36_RS26100	COG0489	protein tyrosine kinase activity
EXW36_RS26105	COG3944	biosynthesis protein
EXW36_RS26110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_RS26115	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS26120	COG1215	transferase activity, transferring glycosyl groups
EXW36_RS26120	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_RS26130	COG1134	teichoic acid transport
EXW36_RS26135	COG1682	transport, permease protein
EXW36_RS26140	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_RS26145	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_RS26150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EXW36_RS26160	COG1609	Transcriptional regulator
EXW36_RS26170	COG0739	heme binding
EXW36_RS26185	COG4555	ABC transporter
EXW36_RS26190	COG2385	sporulation resulting in formation of a cellular spore
EXW36_RS26205	COG4836	Membrane
EXW36_RS26210	COG1007	ATP synthesis coupled electron transport
EXW36_RS26215	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_RS26220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW36_RS26225	COG0713	ATP synthesis coupled electron transport
EXW36_RS26230	COG0839	Belongs to the complex I subunit 6 family
EXW36_RS26240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW36_RS26245	COG0649	NAD binding
EXW36_RS26250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_RS26255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_RS26260	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW36_RS26265	COG3300	MHYT domain
EXW36_RS26265	COG5001	Diguanylate cyclase
EXW36_RS26280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW36_RS26285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW36_RS26290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW36_RS26295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW36_RS26300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW36_RS26305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW36_RS26315	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW36_RS26340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW36_RS26350	COG0698	ribose 5-phosphate isomerase
EXW36_RS26360	COG2190	(PTS) system
EXW36_RS26365	COG2259	Doxx family
EXW36_RS26370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW36_RS26380	COG1971	Probably functions as a manganese efflux pump
EXW36_RS26385	COG0009	L-threonylcarbamoyladenylate synthase
EXW36_RS26400	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW36_RS26405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW36_RS26410	COG1435	thymidine kinase activity
EXW36_RS26420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW36_RS26425	COG1494	fructose-1,6-bisphosphatase
EXW36_RS26445	COG4821	SIS domain
EXW36_RS26450	COG0504	CTP synthase activity
EXW36_RS26465	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS26470	COG1960	acyl-CoA dehydrogenase activity
EXW36_RS26475	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW36_RS26480	COG0183	Belongs to the thiolase family
EXW36_RS26485	COG2181	nitrate reductase activity
EXW36_RS26485	COG0247	lactate metabolic process
EXW36_RS26490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS26495	COG4294	response to UV
EXW36_RS26500	COG5001	Diguanylate cyclase
EXW36_RS26500	COG3300	MHYT domain
EXW36_RS26520	COG2197	response regulator
EXW36_RS26525	COG4585	Histidine kinase
EXW36_RS26530	COG0842	Transport permease protein
EXW36_RS26535	COG1131	(ABC) transporter
EXW36_RS26540	COG0024	Methionine aminopeptidase
EXW36_RS26545	COG2234	aminopeptidase activity
EXW36_RS26565	COG4506	Protein conserved in bacteria
EXW36_RS26570	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW36_RS26585	COG0010	Belongs to the arginase family
EXW36_RS26590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW36_RS26595	COG2814	Major facilitator Superfamily
EXW36_RS26600	COG0789	Transcriptional regulator
EXW36_RS26605	COG0584	glycerophosphoryl diester phosphodiesterase
EXW36_RS26610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW36_RS26620	COG1994	Peptidase M50
EXW36_RS26630	COG1078	dGTPase activity
EXW36_RS26635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW36_RS26640	COG1120	ATPase activity
EXW36_RS26645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS26650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW36_RS26655	COG4844	belongs to the
EXW36_RS26670	COG0280	phosphate acetyltransferase
EXW36_RS26675	COG3253	May function as heme-dependent peroxidase
EXW36_RS26685	COG3773	Cell wall hydrolase
EXW36_RS26695	COG2363	Small membrane protein
EXW36_RS26710	COG2233	PERMEase
EXW36_RS26715	COG0561	phosphatase activity
EXW36_RS26720	COG2814	Major facilitator Superfamily
EXW36_RS26725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW36_RS26730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW36_RS26735	COG1131	(ABC) transporter
EXW36_RS26740	COG2755	lipolytic protein G-D-S-L family
EXW36_RS26745	COG1609	Transcriptional regulator
EXW36_RS26755	COG0460	homoserine dehydrogenase
EXW36_RS26760	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW36_RS26765	COG2873	o-acetylhomoserine
EXW36_RS26780	COG2197	response regulator
EXW36_RS26785	COG2203	Gaf domain
EXW36_RS26785	COG4585	Histidine kinase
EXW36_RS26790	COG0351	phosphomethylpyrimidine kinase
EXW36_RS26800	COG2879	small protein
EXW36_RS26805	COG1966	Carbon starvation protein
EXW36_RS26810	COG3279	Response regulator of the LytR AlgR family
EXW36_RS26815	COG0477	Major facilitator Superfamily
EXW36_RS26850	COG1607	acyl-coa hydrolase
EXW36_RS26855	COG1216	Glycosyl transferase, family 2
EXW36_RS26865	COG1216	Glycosyl transferase, family 2
EXW36_RS26875	COG4485	Bacterial membrane protein, YfhO
EXW36_RS26880	COG0463	Glycosyl transferase, family 2
EXW36_RS26895	COG1309	transcriptional regulator
EXW36_RS26900	COG0488	(ABC) transporter
EXW36_RS26905	COG1309	transcriptional regulator
EXW36_RS26910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW36_RS26915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_RS26915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW36_RS26920	COG0628	permease
EXW36_RS26930	COG1380	Effector of murein hydrolase LrgA
EXW36_RS26935	COG3279	Response regulator of the LytR AlgR family
EXW36_RS26940	COG3275	phosphorelay sensor kinase activity
EXW36_RS26945	COG2814	Major facilitator Superfamily
EXW36_RS26950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW36_RS26955	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW36_RS26960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW36_RS26985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW36_RS26990	COG1272	protein, Hemolysin III
EXW36_RS27015	COG1164	Oligoendopeptidase f
EXW36_RS27025	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW36_RS27035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW36_RS27040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW36_RS27045	COG4853	Protein conserved in bacteria
EXW36_RS27055	COG5002	protein histidine kinase activity
EXW36_RS27060	COG0745	RESPONSE REGULATOR receiver
EXW36_RS27090	COG0305	Participates in initiation and elongation during chromosome replication
EXW36_RS27095	COG0359	binds to the 23S rRNA
EXW36_RS27100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW36_RS27105	COG4241	membrane
EXW36_RS27115	COG0629	single-stranded DNA binding
EXW36_RS27120	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW36_RS27125	COG0012	GTP binding
EXW36_RS27130	COG4481	Protein conserved in bacteria
EXW36_RS27135	COG0668	transmembrane transport
EXW36_RS27145	COG1475	DNA binding
EXW36_RS27150	COG1192	Involved in chromosome partitioning
EXW36_RS27155	COG1475	DNA binding
EXW36_RS27160	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW36_RS27165	COG0445	tRNA wobble uridine modification
EXW36_RS27170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW36_RS27175	COG1847	R3H domain protein
EXW36_RS27180	COG0706	membrane insertase activity
EXW36_RS27185	COG0594	ribonuclease P activity
EXW36_RS27190	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW36_RS27265	COG3344	reverse transcriptase
EXW36_RS27270	COG0791	NLP P60 protein
EXW36_RS27270	COG0741	lytic transglycosylase activity
EXW36_RS27285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW36_RS27300	COG0596	Alpha beta hydrolase
EXW36_RS27380	COG3773	Cell wall hydrolase
EXW36_RS27420	COG1999	signal sequence binding
EXW36_RS27425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW36_RS27430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW36_RS27445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_RS27460	COG1674	ftsk spoiiie
EXW36_RS27475	COG2002	toxin-antitoxin pair type II binding
EXW36_RS27500	COG0741	lytic transglycosylase activity
EXW36_RS27525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW36_RS27550	COG2002	toxin-antitoxin pair type II binding
EXW36_RS27590	COG0457	Tetratricopeptide repeat
EXW36_RS28155	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_RS28155	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS28165	COG3227	Zinc metalloprotease (Elastase)
EXW36_RS28185	COG1136	(ABC) transporter
EXW36_RS28190	COG0577	efflux transmembrane transporter activity
EXW36_RS28250	COG3409	Peptidoglycan-binding domain 1 protein
EXW36_RS28250	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW36_RS28315	COG0658	competence protein
EXW36_RS28315	COG2333	competence protein COMEC
EXW36_RS28340	COG2002	toxin-antitoxin pair type II binding
EXW36_RS28355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EXW36_RS28410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW36_RS28490	COG4974	Belongs to the 'phage' integrase family
EXW36_RS28635	COG0582	viral genome integration into host DNA
EXW36_RS28665	COG2002	toxin-antitoxin pair type II binding
EXW36_RS28680	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW36_RS28705	COG2814	Major facilitator Superfamily
EXW36_RS28750	COG1136	(ABC) transporter
EXW36_RS28755	COG0577	efflux transmembrane transporter activity
EXW36_RS28795	COG0519	Catalyzes the synthesis of GMP from XMP
EXW36_RS28825	COG0640	Transcriptional regulator
EXW36_RS28865	COG4641	Protein conserved in bacteria
EXW36_RS28870	COG2089	acid synthase
EXW36_RS28885	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW36_RS28890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW36_RS28895	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW36_RS28900	COG1086	Polysaccharide biosynthesis protein
EXW36_RS28905	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW36_RS28910	COG0463	Glycosyl transferase, family 2
EXW36_RS28915	COG0463	Glycosyl transferase, family 2
EXW36_RS28970	COG0756	dUTP diphosphatase activity
EXW36_RS28990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW36_RS28990	COG2755	lipolytic protein G-D-S-L family
EXW36_RS29020	COG2720	vancomycin resistance protein
EXW36_RS29065	COG1073	alpha beta
EXW36_RS29075	COG1942	4-Oxalocrotonate Tautomerase
EXW36_RS29080	COG0583	DNA-binding transcription factor activity
EXW36_RS29135	COG2801	Transposase and inactivated derivatives
EXW36_RS29165	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW36_RS29165	COG2755	lipolytic protein G-D-S-L family
EXW36_RS29255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW36_RS29345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_RS29390	COG4974	Belongs to the 'phage' integrase family
EXW36_RS29400	COG0768	penicillin binding
EXW36_RS29445	COG2732	(Barnase) inhibitor
EXW36_RS29550	COG0582	viral genome integration into host DNA
EXW36_RS29565	COG2378	regulation of single-species biofilm formation
EXW36_RS29570	COG2318	DinB family
EXW36_RS29590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW36_RS29600	COG1595	DNA-templated transcription, initiation
EXW36_RS29625	COG2002	toxin-antitoxin pair type II binding
EXW36_RS29720	COG3271	cysteine-type peptidase activity
EXW36_RS29720	COG2274	protein secretion by the type I secretion system
EXW36_RS29725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW36_RS29730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EXW36_RS29750	COG3209	COG3209 Rhs family protein
EXW36_RS29790	COG0531	amino acid
EXW36_RS29830	COG2226	methyltransferase
EXW36_RS29840	COG4555	ABC transporter
EXW36_RS29860	COG0720	synthase
EXW36_RS29870	COG0302	gtp cyclohydrolase
EXW36_RS29925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW36_RS29980	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW36_RS29990	COG2707	UPF0756 membrane protein
EXW36_RS29995	COG0596	Alpha beta hydrolase
EXW36_RS30000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW36_RS30020	COG2267	carboxylic ester hydrolase activity
EXW36_RS30025	COG1309	transcriptional regulator
EXW36_RS30040	COG1285	pathogenesis
EXW36_RS30045	COG0833	amino acid
EXW36_RS30065	COG0494	nUDIX hydrolase
EXW36_RS30150	COG3883	PFAM NLP P60 protein
EXW36_RS30150	COG0791	NLP P60 protein
EXW36_RS30280	COG1192	Involved in chromosome partitioning
EXW36_RS30375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW36_RS30375	COG0551	DNA topoisomerase type I activity
EXW36_RS30410	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW36_RS30455	COG0463	Glycosyl transferase, family 2
EXW36_RS30480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW36_RS30485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW36_RS30490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW36_RS30495	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS30510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_RS30515	COG0438	transferase activity, transferring glycosyl groups
EXW36_RS30520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW36_RS30610	COG3773	Cell wall hydrolase
EXW36_RS30690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW36_RS30715	COG4166	transmembrane transport
EXW36_RS30740	COG1192	Involved in chromosome partitioning
EXW36_RS30840	COG0582	viral genome integration into host DNA
EXW36_RS30870	COG2323	membrane
EXW36_RS30905	COG0662	Cupin 2, conserved barrel domain protein
EXW36_RS31045	COG2814	Major facilitator Superfamily
EXW36_RS31100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_RS31100	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW36_RS31190	COG5444	nuclease activity
EXW36_RS31205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS31210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW36_RS31410	COG2373	Large extracellular alpha-helical protein