locus-tag	class	description
EXW34_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW34_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW34_RS00015	COG2501	S4 domain
EXW34_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW34_RS00025	COG0187	DNA topoisomerase II activity
EXW34_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW34_RS00065	COG0516	GMP reductase activity
EXW34_RS00065	COG0517	IMP dehydrogenase activity
EXW34_RS00070	COG1686	Belongs to the peptidase S11 family
EXW34_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW34_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW34_RS00100	COG1428	Deoxynucleoside kinase
EXW34_RS00105	COG1428	Deoxynucleoside kinase
EXW34_RS00110	COG1335	isochorismatase
EXW34_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW34_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW34_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW34_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW34_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW34_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW34_RS00190	COG0470	DNA polymerase III
EXW34_RS00195	COG1774	PSP1 C-terminal conserved region
EXW34_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW34_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW34_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW34_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW34_RS00230	COG0084	hydrolase, TatD family'
EXW34_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW34_RS00250	COG4466	Protein conserved in bacteria
EXW34_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW34_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW34_RS00270	COG0251	oxidation-reduction process
EXW34_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW34_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW34_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW34_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW34_RS00310	COG2244	polysaccharide biosynthetic process
EXW34_RS00315	COG3956	TIGRFAM MazG family protein
EXW34_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW34_RS00340	COG1098	S1 RNA binding domain
EXW34_RS00355	COG2208	phosphoserine phosphatase activity
EXW34_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW34_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW34_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW34_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW34_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW34_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW34_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW34_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW34_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW34_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW34_RS00420	COG1396	sequence-specific DNA binding
EXW34_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW34_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW34_RS00515	COG3880	PFAM UvrB UvrC protein
EXW34_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW34_RS00525	COG0542	response to heat
EXW34_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW34_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW34_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW34_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW34_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW34_RS00560	COG1045	serine acetyltransferase
EXW34_RS00565	COG0215	cysteine-tRNA ligase activity
EXW34_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW34_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW34_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW34_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW34_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW34_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW34_RS00610	COG0081	regulation of translation
EXW34_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW34_RS00620	COG0222	ribosome binding
EXW34_RS00625	COG2813	Specifically methylates the guanine in position
EXW34_RS00630	COG0085	RNA polymerase activity
EXW34_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW34_RS00640	COG1358	cellular component organization or biogenesis
EXW34_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW34_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW34_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW34_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW34_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW34_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW34_RS00680	COG0089	rRNA binding
EXW34_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW34_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW34_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW34_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW34_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW34_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW34_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW34_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW34_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW34_RS00760	COG1841	ribosomal large subunit assembly
EXW34_RS00765	COG0200	Binds to the 23S rRNA
EXW34_RS00770	COG0201	protein transport
EXW34_RS00775	COG0563	adenylate kinase activity
EXW34_RS00780	COG0024	Methionine aminopeptidase
EXW34_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW34_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW34_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW34_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW34_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW34_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW34_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS00855	COG0489	protein tyrosine kinase activity
EXW34_RS00865	COG2194	sulfuric ester hydrolase activity
EXW34_RS00870	COG0726	polysaccharide deacetylase
EXW34_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW34_RS00955	COG4856	YbbR-like protein
EXW34_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW34_RS00975	COG4946	Tricorn protease homolog
EXW34_RS00975	COG1506	peptidase
EXW34_RS00975	COG0823	Involved in the tonB-independent uptake of proteins
EXW34_RS00990	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS00995	COG2011	ABC-type metal ion transport system permease component
EXW34_RS01005	COG1464	Belongs to the NlpA lipoprotein family
EXW34_RS01020	COG0277	FAD linked oxidase domain protein
EXW34_RS01025	COG2271	Major facilitator Superfamily
EXW34_RS01035	COG2814	Major facilitator Superfamily
EXW34_RS01050	COG0601	transmembrane transport
EXW34_RS01055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW34_RS01060	COG0444	Belongs to the ABC transporter superfamily
EXW34_RS01065	COG4608	Belongs to the ABC transporter superfamily
EXW34_RS01070	COG4166	transmembrane transport
EXW34_RS01080	COG2207	Transcriptional regulator
EXW34_RS01095	COG4166	transmembrane transport
EXW34_RS01100	COG4166	transmembrane transport
EXW34_RS01105	COG0656	L-ascorbic acid biosynthetic process
EXW34_RS01110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW34_RS01125	COG4149	molybdate abc transporter
EXW34_RS01130	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW34_RS01135	COG1910	domain protein
EXW34_RS01150	COG0697	spore germination
EXW34_RS01165	COG0204	Acyl-transferase
EXW34_RS01175	COG1609	Transcriptional regulator
EXW34_RS01185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS01200	COG5298	Protein conserved in bacteria
EXW34_RS01220	COG0488	(ABC) transporter
EXW34_RS01225	COG4585	Histidine kinase
EXW34_RS01230	COG2197	response regulator
EXW34_RS01235	COG1131	(ABC) transporter
EXW34_RS01240	COG1511	domain protein
EXW34_RS01240	COG0842	Transport permease protein
EXW34_RS01245	COG0842	Transport permease protein
EXW34_RS01255	COG0747	negative chemotaxis
EXW34_RS01265	COG0601	transmembrane transport
EXW34_RS01270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW34_RS01275	COG0444	Belongs to the ABC transporter superfamily
EXW34_RS01280	COG4608	Belongs to the ABC transporter superfamily
EXW34_RS01285	COG0561	phosphatase activity
EXW34_RS01320	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW34_RS01325	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW34_RS01335	COG0531	amino acid
EXW34_RS01340	COG2814	Major facilitator Superfamily
EXW34_RS01350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW34_RS01360	COG4294	response to UV
EXW34_RS01365	COG0705	Rhomboid family
EXW34_RS01370	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW34_RS01375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW34_RS01385	COG0864	Transcriptional regulator
EXW34_RS01390	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW34_RS01395	COG2183	response to ionizing radiation
EXW34_RS01495	COG0802	atpase or kinase
EXW34_RS01500	COG1214	PFAM Peptidase M22, glycoprotease
EXW34_RS01505	COG0456	acetyltransferase
EXW34_RS01515	COG0488	(ABC) transporter
EXW34_RS01520	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW34_RS01530	COG1266	CAAX protease self-immunity
EXW34_RS01535	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW34_RS01540	COG0459	protein refolding
EXW34_RS01545	COG0519	Catalyzes the synthesis of GMP from XMP
EXW34_RS01545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW34_RS01550	COG2252	PERMEase
EXW34_RS01560	COG5002	protein histidine kinase activity
EXW34_RS01580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW34_RS01615	COG0693	protein deglycase activity
EXW34_RS01670	COG2205	protein histidine kinase activity
EXW34_RS01675	COG0745	RESPONSE REGULATOR receiver
EXW34_RS01695	COG0697	spore germination
EXW34_RS01720	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW34_RS01725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW34_RS01730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW34_RS01735	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW34_RS01740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW34_RS01745	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW34_RS01750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW34_RS01755	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW34_RS01760	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW34_RS01765	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW34_RS01770	COG0138	bifunctional purine biosynthesis protein purh
EXW34_RS01775	COG0151	Belongs to the GarS family
EXW34_RS01795	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW34_RS01800	COG0210	DNA helicase
EXW34_RS01805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW34_RS01810	COG4851	CamS sex pheromone cAM373 precursor
EXW34_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS01825	COG1335	isochorismatase
EXW34_RS01835	COG2011	ABC-type metal ion transport system permease component
EXW34_RS01840	COG1464	Belongs to the NlpA lipoprotein family
EXW34_RS01855	COG0003	Pfam Anion-transporting ATPase
EXW34_RS01860	COG1846	Transcriptional regulator
EXW34_RS01865	COG4682	membrane
EXW34_RS01875	COG0154	amidase activity
EXW34_RS01880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW34_RS01885	COG1597	lipid kinase activity
EXW34_RS01895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS01905	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS01910	COG2076	Multidrug Resistance protein
EXW34_RS01915	COG2309	aminopeptidase activity
EXW34_RS01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS01940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW34_RS01945	COG5002	protein histidine kinase activity
EXW34_RS01950	COG4807	Protein conserved in bacteria
EXW34_RS01975	COG1757	Na H antiporter
EXW34_RS01980	COG1473	amidohydrolase
EXW34_RS01995	COG0450	alkyl hydroperoxide reductase
EXW34_RS02005	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW34_RS02015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS02020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS02025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS02030	COG0492	ferredoxin-NADP+ reductase activity
EXW34_RS02040	COG0166	Belongs to the GPI family
EXW34_RS02065	COG5002	protein histidine kinase activity
EXW34_RS02085	COG3541	Predicted nucleotidyltransferase
EXW34_RS02090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW34_RS02090	COG0723	plastoquinol--plastocyanin reductase activity
EXW34_RS02100	COG0765	amino acid transport
EXW34_RS02105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS02115	COG0840	transmembrane signaling receptor activity
EXW34_RS02125	COG0366	Alpha amylase catalytic
EXW34_RS02130	COG2190	(PTS) system
EXW34_RS02130	COG1263	PTS System
EXW34_RS02130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS02150	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW34_RS02155	COG0352	thiamine-phosphate diphosphorylase activity
EXW34_RS02160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW34_RS02175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW34_RS02185	COG1116	anion transmembrane transporter activity
EXW34_RS02190	COG0488	(ABC) transporter
EXW34_RS02235	COG2270	Major facilitator Superfamily
EXW34_RS02265	COG2310	stress, protein
EXW34_RS02270	COG2310	stress, protein
EXW34_RS02275	COG2310	stress, protein
EXW34_RS02280	COG0861	Integral membrane protein TerC family
EXW34_RS02290	COG3853	Toxic anion resistance protein (TelA)
EXW34_RS02300	COG4840	Belongs to the UPF0435 family
EXW34_RS02305	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW34_RS02315	COG1295	ribonuclease BN
EXW34_RS02320	COG2217	Heavy metal translocating P-type atpase
EXW34_RS02325	COG0697	spore germination
EXW34_RS02345	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS02360	COG3871	stress protein (general stress protein 26)
EXW34_RS02365	COG0387	Pfam Sodium calcium exchanger
EXW34_RS02375	COG0535	radical SAM domain protein
EXW34_RS02395	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW34_RS02415	COG3829	transcription factor binding
EXW34_RS02425	COG0833	amino acid
EXW34_RS02430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW34_RS02450	COG2066	Belongs to the glutaminase family
EXW34_RS02455	COG1263	PTS System
EXW34_RS02455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS02460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS02475	COG1216	Glycosyl transferase, family 2
EXW34_RS02485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW34_RS02485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW34_RS02490	COG0463	Glycosyl transferase, family 2
EXW34_RS02505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW34_RS02510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW34_RS02525	COG1228	amidohydrolase
EXW34_RS02530	COG1090	epimerase
EXW34_RS02535	COG2137	regulation of response to DNA damage stimulus
EXW34_RS02560	COG1988	membrane-bound metal-dependent
EXW34_RS02565	COG1194	a g-specific adenine glycosylase
EXW34_RS02585	COG3557	Belongs to the UPF0374 family
EXW34_RS02590	COG1132	(ABC) transporter
EXW34_RS02595	COG4129	membrane
EXW34_RS02600	COG0069	glutamate synthase activity
EXW34_RS02600	COG0070	glutamate synthase
EXW34_RS02600	COG0067	glutamate synthase
EXW34_RS02605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW34_RS02610	COG4555	ABC transporter
EXW34_RS02630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW34_RS02635	COG0735	belongs to the Fur family
EXW34_RS02740	COG4974	Belongs to the 'phage' integrase family
EXW34_RS02795	COG0457	Tetratricopeptide repeat
EXW34_RS02815	COG4974	Belongs to the 'phage' integrase family
EXW34_RS02825	COG3646	Phage regulatory protein
EXW34_RS02865	COG4974	Belongs to the 'phage' integrase family
EXW34_RS02905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW34_RS02910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW34_RS02930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW34_RS02940	COG2766	serine protein kinase
EXW34_RS02945	COG2718	Belongs to the UPF0229 family
EXW34_RS02960	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW34_RS02965	COG2268	Band 7 protein
EXW34_RS02970	COG3290	protein histidine kinase activity
EXW34_RS02975	COG4565	transcriptional regulatory protein
EXW34_RS02980	COG2851	Citrate transporter
EXW34_RS03005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW34_RS03010	COG3842	ATPase activity
EXW34_RS03015	COG1175	transmembrane transport
EXW34_RS03020	COG0395	ABC-type sugar transport system, permease component
EXW34_RS03030	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW34_RS03035	COG0745	RESPONSE REGULATOR receiver
EXW34_RS03040	COG5002	protein histidine kinase activity
EXW34_RS03050	COG4990	cell redox homeostasis
EXW34_RS03060	COG3290	protein histidine kinase activity
EXW34_RS03065	COG4565	transcriptional regulatory protein
EXW34_RS03070	COG3493	citrate carrier protein
EXW34_RS03075	COG0281	malic enzyme
EXW34_RS03085	COG0697	spore germination
EXW34_RS03090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS03100	COG5002	protein histidine kinase activity
EXW34_RS03105	COG0745	RESPONSE REGULATOR receiver
EXW34_RS03110	COG0456	acetyltransferase
EXW34_RS03115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW34_RS03120	COG3383	formate dehydrogenase (NAD+) activity
EXW34_RS03125	COG2427	Protein of unknown function (DUF1641)
EXW34_RS03140	COG0531	amino acid
EXW34_RS03150	COG0640	Transcriptional regulator
EXW34_RS03155	COG2217	Heavy metal translocating P-type atpase
EXW34_RS03160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW34_RS03175	COG3227	Zinc metalloprotease (Elastase)
EXW34_RS03195	COG2720	vancomycin resistance protein
EXW34_RS03200	COG1316	TRANSCRIPTIONal
EXW34_RS03205	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS03210	COG0346	lactoylglutathione lyase activity
EXW34_RS03215	COG1253	flavin adenine dinucleotide binding
EXW34_RS03220	COG1027	Aspartate ammonia-lyase
EXW34_RS03225	COG1620	l-lactate permease
EXW34_RS03230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS03245	COG3104	oligopeptide transport
EXW34_RS03250	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS03255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS03260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS03275	COG0156	8-amino-7-oxononanoate synthase activity
EXW34_RS03280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW34_RS03290	COG4548	von Willebrand factor, type A
EXW34_RS03295	COG0714	Associated with various cellular activities
EXW34_RS03315	COG0531	amino acid
EXW34_RS03320	COG2188	Transcriptional regulator
EXW34_RS03325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS03325	COG1263	PTS System
EXW34_RS03330	COG0366	Alpha amylase catalytic
EXW34_RS03340	COG4585	Histidine kinase
EXW34_RS03345	COG2197	response regulator
EXW34_RS03350	COG1404	Belongs to the peptidase S8 family
EXW34_RS03365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW34_RS03370	COG1115	amino acid carrier protein
EXW34_RS03375	COG1126	abc transporter atp-binding protein
EXW34_RS03380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS03385	COG0765	amino acid transport
EXW34_RS03390	COG0765	amino acid transport
EXW34_RS03395	COG0833	amino acid
EXW34_RS03410	COG2378	regulation of single-species biofilm formation
EXW34_RS03415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW34_RS03420	COG5002	protein histidine kinase activity
EXW34_RS03435	COG0659	secondary active sulfate transmembrane transporter activity
EXW34_RS03450	COG0747	negative chemotaxis
EXW34_RS03460	COG0601	transmembrane transport
EXW34_RS03465	COG4608	Belongs to the ABC transporter superfamily
EXW34_RS03475	COG2271	Major facilitator Superfamily
EXW34_RS03480	COG1846	Transcriptional regulator
EXW34_RS03485	COG0477	Major facilitator Superfamily
EXW34_RS03490	COG1609	Transcriptional regulator
EXW34_RS03495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW34_RS03500	COG1869	D-ribose catabolic process
EXW34_RS03510	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW34_RS03515	COG1879	ABC-type sugar transport system periplasmic component
EXW34_RS03545	COG1063	alcohol dehydrogenase
EXW34_RS03560	COG3568	Endonuclease Exonuclease Phosphatase
EXW34_RS03590	COG0840	transmembrane signaling receptor activity
EXW34_RS03595	COG1388	LysM domain
EXW34_RS03595	COG3584	3D domain protein
EXW34_RS03600	COG1476	TRANSCRIPTIONal
EXW34_RS03620	COG3104	oligopeptide transport
EXW34_RS03625	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS03640	COG1113	amino acid transport
EXW34_RS03645	COG2252	PERMEase
EXW34_RS03660	COG2153	protein acetylation
EXW34_RS03670	COG0475	glutathione-regulated potassium exporter activity
EXW34_RS03670	COG0569	domain protein
EXW34_RS03680	COG1845	cytochrome c oxidase, subunit III
EXW34_RS03685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW34_RS03695	COG0833	amino acid
EXW34_RS03700	COG4990	cell redox homeostasis
EXW34_RS03715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW34_RS03720	COG0697	spore germination
EXW34_RS03725	COG0531	amino acid
EXW34_RS03735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW34_RS03740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW34_RS03750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW34_RS03755	COG0573	inorganic phosphate transmembrane transporter activity
EXW34_RS03760	COG0581	inorganic phosphate transmembrane transporter activity
EXW34_RS03765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW34_RS03885	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW34_RS03900	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS03900	COG3103	Sh3 type 3 domain protein
EXW34_RS03900	COG4991	sh3 domain protein
EXW34_RS03905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW34_RS03910	COG1116	anion transmembrane transporter activity
EXW34_RS03915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW34_RS03920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW34_RS03925	COG0352	thiamine-phosphate diphosphorylase activity
EXW34_RS03930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW34_RS03935	COG2104	thiamine diphosphate biosynthetic process
EXW34_RS03940	COG2022	thiamine diphosphate biosynthetic process
EXW34_RS03945	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW34_RS03950	COG0351	phosphomethylpyrimidine kinase
EXW34_RS03975	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW34_RS03980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW34_RS03985	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW34_RS03990	COG2205	protein histidine kinase activity
EXW34_RS03995	COG2814	Major facilitator Superfamily
EXW34_RS04000	COG1846	Transcriptional regulator
EXW34_RS04020	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW34_RS04025	COG1129	ABC transporter
EXW34_RS04030	COG1879	ABC-type sugar transport system periplasmic component
EXW34_RS04035	COG2252	PERMEase
EXW34_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS04100	COG0778	Nitroreductase
EXW34_RS04105	COG2719	SpoVR family
EXW34_RS04125	COG1937	Protein conserved in bacteria
EXW34_RS04130	COG0425	Belongs to the sulfur carrier protein TusA family
EXW34_RS04130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS04135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS04135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS04140	COG0425	Belongs to the sulfur carrier protein TusA family
EXW34_RS04145	COG0425	Belongs to the sulfur carrier protein TusA family
EXW34_RS04145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS04150	COG2210	Belongs to the sulfur carrier protein TusA family
EXW34_RS04155	COG0730	response to heat
EXW34_RS04165	COG1316	TRANSCRIPTIONal
EXW34_RS04170	COG0604	alcohol dehydrogenase
EXW34_RS04175	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW34_RS04180	COG0604	alcohol dehydrogenase
EXW34_RS04185	COG2814	Major facilitator Superfamily
EXW34_RS04195	COG3711	transcriptional antiterminator
EXW34_RS04195	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW34_RS04200	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW34_RS04205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW34_RS04230	COG3584	3D domain protein
EXW34_RS04230	COG1388	LysM domain
EXW34_RS04235	COG0577	efflux transmembrane transporter activity
EXW34_RS04240	COG1136	(ABC) transporter
EXW34_RS04250	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW34_RS04265	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS04270	COG3546	catalase activity
EXW34_RS04295	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS04325	COG0531	amino acid
EXW34_RS04340	COG1737	Transcriptional regulator
EXW34_RS04345	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW34_RS04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS04350	COG1263	PTS System
EXW34_RS04360	COG2259	Doxx family
EXW34_RS04380	COG0697	spore germination
EXW34_RS04385	COG1522	sequence-specific DNA binding
EXW34_RS04395	COG0300	oxidoreductase activity
EXW34_RS04410	COG2076	Multidrug Resistance protein
EXW34_RS04415	COG1309	transcriptional regulator
EXW34_RS04420	COG2814	Major facilitator Superfamily
EXW34_RS04425	COG1733	regulation of RNA biosynthetic process
EXW34_RS04435	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW34_RS04445	COG4533	DNA binding
EXW34_RS04450	COG2211	Major facilitator Superfamily
EXW34_RS04460	COG0693	protein deglycase activity
EXW34_RS04470	COG0531	amino acid
EXW34_RS04475	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS04480	COG1132	(ABC) transporter
EXW34_RS04485	COG1132	(ABC) transporter
EXW34_RS04490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS04495	COG0765	amino acid transport
EXW34_RS04500	COG1126	abc transporter atp-binding protein
EXW34_RS04515	COG0189	ligase activity
EXW34_RS04525	COG4399	Belongs to the UPF0754 family
EXW34_RS04530	COG3679	Belongs to the UPF0342 family
EXW34_RS04545	COG0028	Belongs to the TPP enzyme family
EXW34_RS04550	COG3527	Alpha-acetolactate decarboxylase
EXW34_RS04555	COG0463	Glycosyl transferase, family 2
EXW34_RS04560	COG1216	Glycosyl transferase, family 2
EXW34_RS04565	COG2094	Belongs to the DNA glycosylase MPG family
EXW34_RS04570	COG0561	phosphatase activity
EXW34_RS04580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW34_RS04585	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS04595	COG0659	secondary active sulfate transmembrane transporter activity
EXW34_RS04610	COG0653	protein targeting
EXW34_RS04615	COG2244	polysaccharide biosynthetic process
EXW34_RS04625	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS04630	COG4196	transglutaminase domain protein
EXW34_RS04645	COG1696	Membrane protein involved in D-alanine export
EXW34_RS04660	COG1024	Enoyl-CoA hydratase
EXW34_RS04675	COG1363	Peptidase, m42
EXW34_RS04690	COG2318	DinB family
EXW34_RS04710	COG0579	oxidoreductase
EXW34_RS04745	COG0601	transmembrane transport
EXW34_RS04750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW34_RS04755	COG0444	Belongs to the ABC transporter superfamily
EXW34_RS04760	COG4608	Belongs to the ABC transporter superfamily
EXW34_RS04810	COG0477	Major facilitator Superfamily
EXW34_RS04815	COG3290	protein histidine kinase activity
EXW34_RS04820	COG4565	transcriptional regulatory protein
EXW34_RS04825	COG3181	Tripartite tricarboxylate transporter family receptor
EXW34_RS04830	COG0494	nUDIX hydrolase
EXW34_RS04845	COG1061	Type III restriction enzyme res subunit
EXW34_RS04860	COG0305	Participates in initiation and elongation during chromosome replication
EXW34_RS04890	COG0477	Major facilitator Superfamily
EXW34_RS04930	COG2814	Major facilitator Superfamily
EXW34_RS04935	COG0640	Transcriptional regulator
EXW34_RS04955	COG2376	Dihydroxyacetone kinase
EXW34_RS04965	COG2376	Dihydroxyacetone kinase
EXW34_RS04980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW34_RS04995	COG2720	vancomycin resistance protein
EXW34_RS05050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW34_RS05085	COG1476	TRANSCRIPTIONal
EXW34_RS05110	COG0825	malonyl-CoA metabolic process
EXW34_RS05130	COG3237	CsbD-like
EXW34_RS05150	COG2172	sigma factor antagonist activity
EXW34_RS05155	COG1191	sigma factor activity
EXW34_RS05165	COG2208	phosphoserine phosphatase activity
EXW34_RS05170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW34_RS05175	COG0784	Response regulator, receiver
EXW34_RS05175	COG2205	protein histidine kinase activity
EXW34_RS05175	COG5002	protein histidine kinase activity
EXW34_RS05210	COG2807	transmembrane transport
EXW34_RS05215	COG2186	Transcriptional regulator
EXW34_RS05225	COG4585	Histidine kinase
EXW34_RS05230	COG2197	response regulator
EXW34_RS05260	COG0420	3'-5' exonuclease activity
EXW34_RS05265	COG4717	serine-type aminopeptidase activity
EXW34_RS05270	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW34_RS05275	COG0346	lactoylglutathione lyase activity
EXW34_RS05280	COG0457	Tetratricopeptide repeat
EXW34_RS05290	COG2267	carboxylic ester hydrolase activity
EXW34_RS05305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW34_RS05310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW34_RS05315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW34_RS05320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW34_RS05335	COG1595	DNA-templated transcription, initiation
EXW34_RS05355	COG3973	AAA domain
EXW34_RS05360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW34_RS05375	COG1846	Transcriptional regulator
EXW34_RS05385	COG0537	adenosine 5'-monophosphoramidase activity
EXW34_RS05390	COG1131	(ABC) transporter
EXW34_RS05395	COG4473	ABC transporter
EXW34_RS05410	COG0247	lactate metabolic process
EXW34_RS05415	COG1139	Iron-sulfur cluster binding protein
EXW34_RS05420	COG1556	Lactate utilization protein
EXW34_RS05460	COG3402	PFAM membrane-flanked domain
EXW34_RS05465	COG3428	Bacterial PH domain
EXW34_RS05505	COG3402	PFAM membrane-flanked domain
EXW34_RS05510	COG3428	Bacterial PH domain
EXW34_RS05515	COG2329	Antibiotic biosynthesis monooxygenase
EXW34_RS05520	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW34_RS05525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW34_RS05530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW34_RS05535	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW34_RS05555	COG1309	transcriptional regulator
EXW34_RS05560	COG1511	domain protein
EXW34_RS05595	COG1609	Transcriptional regulator
EXW34_RS05605	COG1234	tRNA 3'-trailer cleavage
EXW34_RS05610	COG0095	Lipoate-protein ligase
EXW34_RS05620	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS05635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW34_RS05640	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW34_RS05645	COG4208	sulfate ABC transporter
EXW34_RS05655	COG3209	COG3209 Rhs family protein
EXW34_RS05690	COG1408	metallophosphoesterase
EXW34_RS05695	COG1078	dGTPase activity
EXW34_RS05710	COG1595	DNA-templated transcription, initiation
EXW34_RS05715	COG3708	Transcriptional regulator
EXW34_RS05715	COG2207	Transcriptional regulator
EXW34_RS05720	COG2205	protein histidine kinase activity
EXW34_RS05725	COG0745	RESPONSE REGULATOR receiver
EXW34_RS05740	COG0501	Belongs to the peptidase M48B family
EXW34_RS05745	COG0697	spore germination
EXW34_RS05770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW34_RS05775	COG2224	Isocitrate lyase
EXW34_RS05785	COG1278	Cold shock
EXW34_RS05805	COG0398	Pfam SNARE associated Golgi protein
EXW34_RS05815	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW34_RS05820	COG1074	ATP-dependent DNA helicase activity
EXW34_RS05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW34_RS05895	COG0367	asparagine synthase
EXW34_RS05905	COG0753	catalase activity
EXW34_RS05910	COG0004	ammonium transporteR
EXW34_RS05920	COG1666	GTP binding
EXW34_RS05925	COG2996	Protein conserved in bacteria
EXW34_RS05940	COG1329	Transcriptional regulator
EXW34_RS05970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW34_RS05980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS05995	COG0561	phosphatase activity
EXW34_RS06015	COG2267	carboxylic ester hydrolase activity
EXW34_RS06030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW34_RS06035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW34_RS06040	COG5504	Zn-dependent protease
EXW34_RS06050	COG0180	Tryptophanyl-tRNA synthetase
EXW34_RS06060	COG4166	transmembrane transport
EXW34_RS06065	COG0601	transmembrane transport
EXW34_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW34_RS06075	COG0444	Belongs to the ABC transporter superfamily
EXW34_RS06080	COG4608	Belongs to the ABC transporter superfamily
EXW34_RS06085	COG0534	Mate efflux family protein
EXW34_RS06090	COG4166	transmembrane transport
EXW34_RS06105	COG0861	Integral membrane protein TerC family
EXW34_RS06110	COG4862	establishment of competence for transformation
EXW34_RS06115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW34_RS06125	COG1164	Oligoendopeptidase f
EXW34_RS06140	COG2346	COG2346, Truncated hemoglobins
EXW34_RS06145	COG4116	CYTH
EXW34_RS06155	COG2357	RelA SpoT domain protein
EXW34_RS06165	COG0564	pseudouridine synthase activity
EXW34_RS06175	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW34_RS06180	COG0772	Belongs to the SEDS family
EXW34_RS06185	COG1216	Glycosyl transferase, family 2
EXW34_RS06205	COG0457	Tetratricopeptide repeat
EXW34_RS06205	COG0463	Glycosyl transferase, family 2
EXW34_RS06225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW34_RS06240	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW34_RS06285	COG2153	protein acetylation
EXW34_RS06295	COG2382	esterase
EXW34_RS06320	COG5492	domain, Protein
EXW34_RS06325	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW34_RS06335	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW34_RS06335	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW34_RS06340	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW34_RS06345	COG0134	indole-3-glycerol-phosphate synthase activity
EXW34_RS06350	COG0135	phosphoribosylanthranilate isomerase activity
EXW34_RS06355	COG0133	tryptophan synthase activity
EXW34_RS06360	COG0159	tryptophan synthase activity
EXW34_RS06370	COG1620	l-lactate permease
EXW34_RS06375	COG5634	Uncharacterized conserved protein (DUF2278)
EXW34_RS06410	COG2226	methyltransferase
EXW34_RS06430	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW34_RS06435	COG0567	Dehydrogenase, E1 component
EXW34_RS06460	COG4152	abc transporter atp-binding protein
EXW34_RS06465	COG1668	transmembrane transport
EXW34_RS06485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EXW34_RS06565	COG0582	viral genome integration into host DNA
EXW34_RS06585	COG1686	Belongs to the peptidase S11 family
EXW34_RS06590	COG0681	Belongs to the peptidase S26 family
EXW34_RS06625	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS06635	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW34_RS06640	COG1177	transmembrane transport
EXW34_RS06645	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW34_RS06655	COG2409	Drug exporters of the RND superfamily
EXW34_RS06665	COG0564	pseudouridine synthase activity
EXW34_RS06675	COG2340	Cysteine-rich secretory protein family
EXW34_RS06680	COG0247	lactate metabolic process
EXW34_RS06685	COG0277	FAD linked oxidase domain protein
EXW34_RS06690	COG3835	regulator
EXW34_RS06700	COG0745	RESPONSE REGULATOR receiver
EXW34_RS06705	COG5002	protein histidine kinase activity
EXW34_RS06710	COG2186	Transcriptional regulator
EXW34_RS06715	COG0247	lactate metabolic process
EXW34_RS06720	COG1139	Iron-sulfur cluster binding protein
EXW34_RS06725	COG1556	Lactate utilization protein
EXW34_RS06730	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW34_RS06740	COG2116	formate transmembrane transporter activity
EXW34_RS06745	COG0861	Integral membrane protein TerC family
EXW34_RS06750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW34_RS06760	COG2030	dehydratase
EXW34_RS06780	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW34_RS06795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW34_RS06810	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW34_RS06815	COG3842	ATPase activity
EXW34_RS06825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW34_RS06830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW34_RS06840	COG1349	DNA-binding transcription factor activity
EXW34_RS06850	COG0235	Class ii aldolase
EXW34_RS06860	COG2861	carbohydrate metabolic process
EXW34_RS06870	COG3852	Histidine kinase
EXW34_RS06875	COG1846	Transcriptional regulator
EXW34_RS06885	COG2318	DinB family
EXW34_RS06890	COG5002	protein histidine kinase activity
EXW34_RS06895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW34_RS06900	COG0720	synthase
EXW34_RS06910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW34_RS06915	COG4873	Protein conserved in bacteria
EXW34_RS06930	COG0456	acetyltransferase
EXW34_RS06945	COG1780	Probably involved in ribonucleotide reductase function
EXW34_RS06960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW34_RS06975	COG2204	response regulator
EXW34_RS06980	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS06990	COG1725	Transcriptional regulator
EXW34_RS06995	COG1131	(ABC) transporter
EXW34_RS07005	COG1131	(ABC) transporter
EXW34_RS07010	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW34_RS07025	COG1522	sequence-specific DNA binding
EXW34_RS07035	COG1335	isochorismatase
EXW34_RS07045	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW34_RS07050	COG2070	2-Nitropropane dioxygenase
EXW34_RS07055	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW34_RS07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW34_RS07065	COG1696	Membrane protein involved in D-alanine export
EXW34_RS07090	COG0716	FMN binding
EXW34_RS07125	COG0534	Mate efflux family protein
EXW34_RS07150	COG1846	Transcriptional regulator
EXW34_RS07160	COG1301	dicarboxylic acid transport
EXW34_RS07165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW34_RS07175	COG3874	Sporulation protein YtfJ
EXW34_RS07195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS07200	COG0028	Belongs to the TPP enzyme family
EXW34_RS07205	COG0440	acetolactate synthase activity
EXW34_RS07215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW34_RS07225	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW34_RS07235	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW34_RS07240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW34_RS07250	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW34_RS07255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW34_RS07260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW34_RS07265	COG0107	imidazoleglycerol-phosphate synthase activity
EXW34_RS07275	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW34_RS07280	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW34_RS07295	COG1183	phosphatidylcholine synthase activity
EXW34_RS07300	COG1368	sulfuric ester hydrolase activity
EXW34_RS07310	COG0019	diaminopimelate decarboxylase activity
EXW34_RS07320	COG0175	sulfate reduction
EXW34_RS07325	COG2046	Belongs to the sulfate adenylyltransferase family
EXW34_RS07330	COG0529	Catalyzes the synthesis of activated sulfate
EXW34_RS07335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW34_RS07355	COG1648	precorrin-2 dehydrogenase activity
EXW34_RS07360	COG0733	neurotransmitter:sodium symporter activity
EXW34_RS07385	COG1757	Na H antiporter
EXW34_RS07405	COG4758	membrane
EXW34_RS07410	COG4585	Histidine kinase
EXW34_RS07415	COG2197	response regulator
EXW34_RS07425	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS07435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW34_RS07475	COG0730	response to heat
EXW34_RS07480	COG0306	phosphate transporter
EXW34_RS07485	COG1392	Phosphate transport regulator
EXW34_RS07490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW34_RS07505	COG3852	Histidine kinase
EXW34_RS07510	COG1801	Protein of unknown function DUF72
EXW34_RS07520	COG0582	viral genome integration into host DNA
EXW34_RS07525	COG5002	protein histidine kinase activity
EXW34_RS07540	COG0392	lysyltransferase activity
EXW34_RS07540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW34_RS07555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW34_RS07560	COG1686	Belongs to the peptidase S11 family
EXW34_RS07565	COG2715	membrane protein required for spore maturation
EXW34_RS07570	COG0700	Nucleoside recognition
EXW34_RS07575	COG1187	pseudouridine synthase activity
EXW34_RS07585	COG1333	cytochrome c biogenesis protein
EXW34_RS07590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW34_RS07595	COG0745	RESPONSE REGULATOR receiver
EXW34_RS07600	COG5002	protein histidine kinase activity
EXW34_RS07605	COG2096	Adenosyltransferase
EXW34_RS07610	COG4942	peptidase
EXW34_RS07620	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW34_RS07625	COG1141	Ferredoxin
EXW34_RS07630	COG4955	Helix-turn-helix domain
EXW34_RS07635	COG0514	ATP-dependent DNA helicase (RecQ)
EXW34_RS07640	COG1266	CAAX protease self-immunity
EXW34_RS07650	COG1408	metallophosphoesterase
EXW34_RS07665	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW34_RS07685	COG0492	ferredoxin-NADP+ reductase activity
EXW34_RS07690	COG0252	asparaginase activity
EXW34_RS07700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW34_RS07710	COG1304	FMN binding
EXW34_RS07740	COG1160	GTP binding
EXW34_RS07745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW34_RS07765	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW34_RS07775	COG0302	gtp cyclohydrolase
EXW34_RS07780	COG0142	geranyltranstransferase activity
EXW34_RS07785	COG2226	methyltransferase
EXW34_RS07790	COG0142	geranyltranstransferase activity
EXW34_RS07805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW34_RS07815	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW34_RS07820	COG0457	Tetratricopeptide repeat
EXW34_RS07825	COG5582	Belongs to the UPF0302 family
EXW34_RS07840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW34_RS07855	COG4347	Protein of unknown function (DUF1405)
EXW34_RS07870	COG2738	Putative neutral zinc metallopeptidase
EXW34_RS07880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS07885	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW34_RS07890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW34_RS07895	COG1803	Methylglyoxal synthase
EXW34_RS07900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW34_RS07905	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS07910	COG0617	tRNA 3'-terminal CCA addition
EXW34_RS07920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW34_RS07925	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW34_RS07935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW34_RS07935	COG1199	ATP-dependent helicase activity
EXW34_RS07955	COG3935	DnaD domain protein
EXW34_RS07960	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW34_RS07970	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW34_RS07970	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW34_RS07975	COG3331	DNA recombination
EXW34_RS08010	COG4474	Belongs to the UPF0398 family
EXW34_RS08015	COG3599	regulation of cell shape
EXW34_RS08025	COG0116	Belongs to the methyltransferase superfamily
EXW34_RS08035	COG1199	ATP-dependent helicase activity
EXW34_RS08040	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW34_RS08050	COG0024	Methionine aminopeptidase
EXW34_RS08060	COG2233	PERMEase
EXW34_RS08065	COG2311	Membrane
EXW34_RS08070	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW34_RS08080	COG0456	acetyltransferase
EXW34_RS08090	COG2897	thiosulfate sulfurtransferase activity
EXW34_RS08130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW34_RS08155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW34_RS08170	COG1215	transferase activity, transferring glycosyl groups
EXW34_RS08175	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS08190	COG0454	-acetyltransferase
EXW34_RS08210	COG0328	RNA-DNA hybrid ribonuclease activity
EXW34_RS08245	COG3403	YqcI/YcgG family
EXW34_RS08250	COG1280	lysine exporter protein (LysE YggA)
EXW34_RS08265	COG3162	membrane
EXW34_RS08270	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW34_RS08275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW34_RS08285	COG0475	glutathione-regulated potassium exporter activity
EXW34_RS08290	COG4978	Transcriptional regulator
EXW34_RS08290	COG0789	Transcriptional regulator
EXW34_RS08300	COG2323	membrane
EXW34_RS08305	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW34_RS08335	COG2814	Major facilitator Superfamily
EXW34_RS08355	COG1923	regulation of RNA biosynthetic process
EXW34_RS08365	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW34_RS08370	COG1360	Flagellar Motor Protein
EXW34_RS08400	COG0861	Integral membrane protein TerC family
EXW34_RS08410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW34_RS08415	COG0741	lytic transglycosylase activity
EXW34_RS08425	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW34_RS08430	COG1776	CheC inhibitor of MCP methylation
EXW34_RS08430	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW34_RS08440	COG1338	Plays a role in the flagellum-specific transport system
EXW34_RS08445	COG1987	bacterial-type flagellum assembly
EXW34_RS08455	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW34_RS08460	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW34_RS08465	COG1419	protein localization to endoplasmic reticulum
EXW34_RS08470	COG4786	Flagellar basal body rod
EXW34_RS08475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW34_RS08515	COG2329	Antibiotic biosynthesis monooxygenase
EXW34_RS08530	COG2814	Major facilitator Superfamily
EXW34_RS08540	COG0583	DNA-binding transcription factor activity
EXW34_RS08545	COG3842	ATPase activity
EXW34_RS08590	COG1686	Belongs to the peptidase S11 family
EXW34_RS08595	COG0406	alpha-ribazole phosphatase activity
EXW34_RS08625	COG0367	asparagine synthase
EXW34_RS08655	COG1802	Transcriptional regulator
EXW34_RS08660	COG0697	spore germination
EXW34_RS08665	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS08665	COG1216	Glycosyl transferase, family 2
EXW34_RS08670	COG1757	Na H antiporter
EXW34_RS08700	COG0534	Mate efflux family protein
EXW34_RS08705	COG3340	Belongs to the peptidase S51 family
EXW34_RS08725	COG0785	Cytochrome C biogenesis protein
EXW34_RS08730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS08745	COG3048	D-serine ammonia-lyase activity
EXW34_RS08750	COG2733	membrane
EXW34_RS08785	COG1131	(ABC) transporter
EXW34_RS08800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW34_RS08805	COG0528	UMP kinase activity
EXW34_RS08815	COG1027	Aspartate ammonia-lyase
EXW34_RS08820	COG0281	malic enzyme
EXW34_RS08825	COG4191	Histidine kinase
EXW34_RS08830	COG0784	Response regulator, receiver
EXW34_RS08835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW34_RS08845	COG2502	aspartate--ammonia ligase
EXW34_RS08880	COG2816	NAD+ diphosphatase activity
EXW34_RS08885	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS08895	COG2814	Major facilitator Superfamily
EXW34_RS08910	COG1966	Carbon starvation protein
EXW34_RS08925	COG0477	Major facilitator Superfamily
EXW34_RS08935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW34_RS08945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW34_RS08950	COG2223	nitrite transmembrane transporter activity
EXW34_RS08955	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW34_RS08965	COG2244	polysaccharide biosynthetic process
EXW34_RS08970	COG0733	neurotransmitter:sodium symporter activity
EXW34_RS08980	COG5566	PFAM Mor transcription activator
EXW34_RS08985	COG2323	membrane
EXW34_RS09010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW34_RS09020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS09025	COG0028	Belongs to the TPP enzyme family
EXW34_RS09040	COG0129	dihydroxy-acid dehydratase activity
EXW34_RS09045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW34_RS09070	COG2814	Major facilitator Superfamily
EXW34_RS09075	COG3384	dioxygenase
EXW34_RS09115	COG4166	transmembrane transport
EXW34_RS09140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS09160	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW34_RS09165	COG1054	Belongs to the UPF0176 family
EXW34_RS09175	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW34_RS09180	COG0531	amino acid
EXW34_RS09200	COG1280	lysine exporter protein (LysE YggA)
EXW34_RS09220	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW34_RS09235	COG4257	antibiotic catabolic process
EXW34_RS09240	COG2390	Transcriptional regulator
EXW34_RS09250	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW34_RS09255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS09260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW34_RS09275	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW34_RS09295	COG0583	DNA-binding transcription factor activity
EXW34_RS09315	COG0006	proline dipeptidase activity
EXW34_RS09320	COG2132	Multicopper oxidase
EXW34_RS09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW34_RS09340	COG0583	DNA-binding transcription factor activity
EXW34_RS09360	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS09370	COG1834	amidinotransferase
EXW34_RS09380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS09425	COG1276	copper resistance
EXW34_RS09425	COG2372	response to copper ion
EXW34_RS09430	COG4549	nuclear export factor GLE1
EXW34_RS09440	COG0697	spore germination
EXW34_RS09445	COG0583	DNA-binding transcription factor activity
EXW34_RS09450	COG1959	2 iron, 2 sulfur cluster binding
EXW34_RS09455	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW34_RS09460	COG0778	Nitroreductase
EXW34_RS09475	COG3547	Transposase (IS116 IS110 IS902 family)
EXW34_RS09485	COG0628	permease
EXW34_RS09500	COG1231	oxidoreductase activity
EXW34_RS09505	COG0523	cobalamin synthesis protein
EXW34_RS09515	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS09520	COG2030	dehydratase
EXW34_RS09540	COG0411	ABC transporter
EXW34_RS09560	COG0583	DNA-binding transcription factor activity
EXW34_RS09570	COG1942	4-Oxalocrotonate Tautomerase
EXW34_RS09585	COG0346	lactoylglutathione lyase activity
EXW34_RS09595	COG1271	oxidase subunit
EXW34_RS09600	COG1294	oxidase, subunit
EXW34_RS09605	COG4988	ABC transporter
EXW34_RS09610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW34_RS09640	COG1686	Belongs to the peptidase S11 family
EXW34_RS09655	COG1388	LysM domain
EXW34_RS09655	COG0791	NLP P60 protein
EXW34_RS09665	COG1132	(ABC) transporter
EXW34_RS09670	COG0745	RESPONSE REGULATOR receiver
EXW34_RS09675	COG5002	protein histidine kinase activity
EXW34_RS09680	COG0300	oxidoreductase activity
EXW34_RS09685	COG4122	O-methyltransferase activity
EXW34_RS09715	COG0460	homoserine dehydrogenase
EXW34_RS09725	COG0083	homoserine kinase activity
EXW34_RS09740	COG1316	TRANSCRIPTIONal
EXW34_RS09750	COG0745	RESPONSE REGULATOR receiver
EXW34_RS09755	COG5002	protein histidine kinase activity
EXW34_RS09775	COG1285	pathogenesis
EXW34_RS09780	COG1247	-acetyltransferase
EXW34_RS09800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW34_RS09810	COG1082	Xylose isomerase domain protein TIM barrel
EXW34_RS09820	COG2814	Major facilitator Superfamily
EXW34_RS09825	COG1279	arginine transmembrane transporter activity
EXW34_RS09830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS09840	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW34_RS09870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW34_RS09875	COG0577	efflux transmembrane transporter activity
EXW34_RS09880	COG2002	toxin-antitoxin pair type II binding
EXW34_RS09885	COG1404	Belongs to the peptidase S8 family
EXW34_RS09890	COG0640	Transcriptional regulator
EXW34_RS09895	COG0667	Aldo Keto reductase
EXW34_RS09940	COG3949	Membrane
EXW34_RS09945	COG0783	Belongs to the Dps family
EXW34_RS09960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW34_RS09970	COG1231	oxidoreductase activity
EXW34_RS09975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS09980	COG4989	oxidoreductase activity
EXW34_RS09985	COG0523	cobalamin synthesis protein
EXW34_RS10000	COG0456	acetyltransferase
EXW34_RS10005	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW34_RS10025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW34_RS10035	COG4166	transmembrane transport
EXW34_RS10040	COG0346	lactoylglutathione lyase activity
EXW34_RS10050	COG0406	alpha-ribazole phosphatase activity
EXW34_RS10060	COG5337	Spore coat protein CotH
EXW34_RS10065	COG1051	belongs to the nudix hydrolase family
EXW34_RS10070	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS10075	COG2244	polysaccharide biosynthetic process
EXW34_RS10085	COG0701	Predicted permease
EXW34_RS10090	COG3689	TIGRFAM TIGR03943 family protein
EXW34_RS10095	COG1607	acyl-coa hydrolase
EXW34_RS10105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW34_RS10120	COG0702	epimerase
EXW34_RS10125	COG2839	Protein conserved in bacteria
EXW34_RS10130	COG1253	flavin adenine dinucleotide binding
EXW34_RS10145	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS10150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW34_RS10165	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS10175	COG1876	peptidase activity
EXW34_RS10180	COG0494	nUDIX hydrolase
EXW34_RS10205	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS10215	COG0561	phosphatase activity
EXW34_RS10225	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW34_RS10230	COG4106	trans-aconitate 2-methyltransferase activity
EXW34_RS10245	COG1819	glycosyl
EXW34_RS10250	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS10255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS10280	COG0456	acetyltransferase
EXW34_RS10340	COG3874	Sporulation protein YtfJ
EXW34_RS10365	COG2226	methyltransferase
EXW34_RS10395	COG0604	alcohol dehydrogenase
EXW34_RS10400	COG1595	DNA-templated transcription, initiation
EXW34_RS10420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW34_RS10420	COG0426	domain, Protein
EXW34_RS10430	COG0386	Belongs to the glutathione peroxidase family
EXW34_RS10435	COG1305	Transglutaminase-like
EXW34_RS10440	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW34_RS10445	COG0714	Associated with various cellular activities
EXW34_RS10450	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW34_RS10455	COG1140	nitrate reductase beta subunit
EXW34_RS10460	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW34_RS10465	COG2181	nitrate reductase activity
EXW34_RS10470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW34_RS10475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW34_RS10480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW34_RS10485	COG0303	'Molybdopterin
EXW34_RS10490	COG0314	molybdopterin synthase activity
EXW34_RS10500	COG2223	nitrite transmembrane transporter activity
EXW34_RS10525	COG1648	precorrin-2 dehydrogenase activity
EXW34_RS10535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW34_RS10535	COG1587	Uroporphyrinogen-III synthase
EXW34_RS10540	COG2146	nitrite reductase [NAD(P)H] activity
EXW34_RS10545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW34_RS10550	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW34_RS10580	COG2359	stage V sporulation protein S
EXW34_RS10630	COG0582	viral genome integration into host DNA
EXW34_RS10650	COG1418	mRNA catabolic process
EXW34_RS10655	COG0488	(ABC) transporter
EXW34_RS10675	COG1413	lyase activity
EXW34_RS10690	COG2521	methyltransferase
EXW34_RS10690	COG2136	Putative SAM-dependent methyltransferase
EXW34_RS10695	COG0018	arginyl-trna synthetase
EXW34_RS10710	COG2226	methyltransferase
EXW34_RS10745	COG0017	Asparaginyl-tRNA synthetase
EXW34_RS10750	COG0733	neurotransmitter:sodium symporter activity
EXW34_RS10775	COG2610	gluconate transmembrane transporter activity
EXW34_RS10785	COG1794	racemase activity, acting on amino acids and derivatives
EXW34_RS10795	COG0456	acetyltransferase
EXW34_RS10800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW34_RS10810	COG1131	(ABC) transporter
EXW34_RS10815	COG4473	ABC transporter
EXW34_RS10825	COG0546	phosphoglycolate phosphatase activity
EXW34_RS10870	COG0768	penicillin binding
EXW34_RS10885	COG1272	protein, Hemolysin III
EXW34_RS10890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW34_RS10895	COG0805	protein transport
EXW34_RS10910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW34_RS10915	COG1999	signal sequence binding
EXW34_RS10920	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW34_RS10925	COG0367	asparagine synthase
EXW34_RS10940	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS10945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS10950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS10965	COG1335	isochorismatase
EXW34_RS10975	COG0668	transmembrane transport
EXW34_RS10980	COG2203	Gaf domain
EXW34_RS10980	COG4585	Histidine kinase
EXW34_RS10985	COG2197	response regulator
EXW34_RS10990	COG1737	Transcriptional regulator
EXW34_RS10995	COG1064	alcohol dehydrogenase
EXW34_RS11015	COG1070	Carbohydrate kinase
EXW34_RS11025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW34_RS11045	COG0517	IMP dehydrogenase activity
EXW34_RS11045	COG1125	glycine betaine transport
EXW34_RS11050	COG1174	glycine betaine transport
EXW34_RS11085	COG1253	flavin adenine dinucleotide binding
EXW34_RS11090	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS11095	COG5506	Protein of unknown function (DUF1694)
EXW34_RS11110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW34_RS11115	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW34_RS11120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW34_RS11125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW34_RS11130	COG0456	acetyltransferase
EXW34_RS11135	COG3829	transcription factor binding
EXW34_RS11140	COG1509	lysine 2,3-aminomutase activity
EXW34_RS11150	COG4479	Belongs to the UPF0346 family
EXW34_RS11175	COG4991	sh3 domain protein
EXW34_RS11175	COG3064	Membrane
EXW34_RS11175	COG0515	serine threonine protein kinase
EXW34_RS11185	COG0671	phosphoesterase, PA-phosphatase related
EXW34_RS11190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW34_RS11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS11250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW34_RS11275	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS11295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW34_RS11295	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW34_RS11305	COG2814	Major facilitator Superfamily
EXW34_RS11315	COG0372	Belongs to the citrate synthase family
EXW34_RS11320	COG2079	MmgE PrpD family protein
EXW34_RS11325	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW34_RS11330	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS11335	COG2084	Dehydrogenase
EXW34_RS11340	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS11345	COG1280	lysine exporter protein (LysE YggA)
EXW34_RS11350	COG1024	Enoyl-CoA hydratase
EXW34_RS11365	COG0420	3'-5' exonuclease activity
EXW34_RS11390	COG2223	nitrite transmembrane transporter activity
EXW34_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS11400	COG1169	isochorismate synthase
EXW34_RS11405	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW34_RS11410	COG3433	isochorismatase activity
EXW34_RS11410	COG1535	isochorismatase
EXW34_RS11415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW34_RS11420	COG3251	PFAM MbtH domain protein
EXW34_RS11425	COG2814	Major facilitator Superfamily
EXW34_RS11440	COG0776	regulation of translation
EXW34_RS11450	COG2318	DinB family
EXW34_RS11455	COG1115	amino acid carrier protein
EXW34_RS11460	COG2329	Antibiotic biosynthesis monooxygenase
EXW34_RS11470	COG1187	pseudouridine synthase activity
EXW34_RS11475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW34_RS11480	COG3655	Transcriptional regulator
EXW34_RS11490	COG1136	(ABC) transporter
EXW34_RS11500	COG0596	Alpha beta hydrolase
EXW34_RS11515	COG0028	Belongs to the TPP enzyme family
EXW34_RS11540	COG1253	flavin adenine dinucleotide binding
EXW34_RS11595	COG1846	Transcriptional regulator
EXW34_RS11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS11610	COG1309	transcriptional regulator
EXW34_RS11640	COG1247	-acetyltransferase
EXW34_RS11670	COG0596	Alpha beta hydrolase
EXW34_RS11675	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW34_RS11685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS11720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW34_RS11735	COG0583	DNA-binding transcription factor activity
EXW34_RS11740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW34_RS11745	COG2258	MOSC domain
EXW34_RS11760	COG1132	(ABC) transporter
EXW34_RS11765	COG1132	(ABC) transporter
EXW34_RS11780	COG0189	ligase activity
EXW34_RS11800	COG1396	sequence-specific DNA binding
EXW34_RS11830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW34_RS11840	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW34_RS11845	COG1595	DNA-templated transcription, initiation
EXW34_RS11870	COG1649	PFAM Uncharacterised BCR, COG1649
EXW34_RS11890	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW34_RS11895	COG2971	BadF BadG BcrA BcrD
EXW34_RS11945	COG1309	transcriptional regulator
EXW34_RS11960	COG0577	efflux transmembrane transporter activity
EXW34_RS11960	COG1136	(ABC) transporter
EXW34_RS11965	COG3615	Tellurite resistance protein tehB
EXW34_RS11965	COG0500	methyltransferase
EXW34_RS11975	COG0693	protein deglycase activity
EXW34_RS11985	COG0588	phosphoglycerate mutase activity
EXW34_RS12025	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW34_RS12040	COG0110	maltose O-acetyltransferase activity
EXW34_RS12045	COG0745	RESPONSE REGULATOR receiver
EXW34_RS12050	COG2205	protein histidine kinase activity
EXW34_RS12055	COG1136	(ABC) transporter
EXW34_RS12075	COG1136	(ABC) transporter
EXW34_RS12105	COG1686	Belongs to the peptidase S11 family
EXW34_RS12130	COG0768	penicillin binding
EXW34_RS12135	COG0745	RESPONSE REGULATOR receiver
EXW34_RS12140	COG2205	protein histidine kinase activity
EXW34_RS12145	COG1136	(ABC) transporter
EXW34_RS12150	COG0577	efflux transmembrane transporter activity
EXW34_RS12160	COG1595	DNA-templated transcription, initiation
EXW34_RS12170	COG0768	penicillin binding
EXW34_RS12175	COG0768	penicillin binding
EXW34_RS12210	COG1252	NADH dehydrogenase
EXW34_RS12215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS12215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS12230	COG0697	spore germination
EXW34_RS12255	COG3397	chitin binding
EXW34_RS12260	COG0823	Involved in the tonB-independent uptake of proteins
EXW34_RS12270	COG1408	metallophosphoesterase
EXW34_RS12280	COG1131	(ABC) transporter
EXW34_RS12290	COG1309	transcriptional regulator
EXW34_RS12300	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS12305	COG0439	Biotin carboxylase
EXW34_RS12310	COG0511	ligase activity, forming carbon-carbon bonds
EXW34_RS12315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW34_RS12320	COG1024	Enoyl-CoA hydratase
EXW34_RS12325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW34_RS12330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW34_RS12375	COG0572	uridine kinase
EXW34_RS12380	COG2318	DinB family
EXW34_RS12385	COG1686	Belongs to the peptidase S11 family
EXW34_RS12410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW34_RS12435	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW34_RS12460	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS12465	COG1733	regulation of RNA biosynthetic process
EXW34_RS12510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS12540	COG2323	membrane
EXW34_RS12555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS12560	COG0697	spore germination
EXW34_RS12565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW34_RS12570	COG0201	protein transport
EXW34_RS12580	COG0737	Belongs to the 5'-nucleotidase family
EXW34_RS12585	COG3227	Zinc metalloprotease (Elastase)
EXW34_RS12590	COG1523	belongs to the glycosyl hydrolase 13 family
EXW34_RS12605	COG0076	glutamate decarboxylase activity
EXW34_RS12610	COG0657	acetylesterase activity
EXW34_RS12615	COG1073	alpha beta
EXW34_RS12625	COG0577	efflux transmembrane transporter activity
EXW34_RS12630	COG1136	(ABC) transporter
EXW34_RS12645	COG5002	protein histidine kinase activity
EXW34_RS12650	COG0745	RESPONSE REGULATOR receiver
EXW34_RS12655	COG1011	Hydrolase
EXW34_RS12680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW34_RS12685	COG1183	phosphatidylcholine synthase activity
EXW34_RS12695	COG1132	(ABC) transporter
EXW34_RS12700	COG3961	Belongs to the TPP enzyme family
EXW34_RS12720	COG0322	excinuclease ABC activity
EXW34_RS12745	COG2318	DinB family
EXW34_RS12760	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW34_RS12810	COG1051	belongs to the nudix hydrolase family
EXW34_RS12815	COG0592	DNA-directed DNA polymerase activity
EXW34_RS12820	COG2816	NAD+ diphosphatase activity
EXW34_RS12830	COG2223	nitrite transmembrane transporter activity
EXW34_RS12840	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS12850	COG0494	nUDIX hydrolase
EXW34_RS12870	COG0697	spore germination
EXW34_RS12875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS12905	COG1733	regulation of RNA biosynthetic process
EXW34_RS12915	COG2814	Major facilitator Superfamily
EXW34_RS12955	COG0768	penicillin binding
EXW34_RS12960	COG0671	phosphoesterase, PA-phosphatase related
EXW34_RS12965	COG0604	alcohol dehydrogenase
EXW34_RS12970	COG5002	protein histidine kinase activity
EXW34_RS12975	COG0745	RESPONSE REGULATOR receiver
EXW34_RS12985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW34_RS12995	COG2205	protein histidine kinase activity
EXW34_RS13010	COG1122	ATPase activity
EXW34_RS13015	COG4720	Psort location CytoplasmicMembrane, score
EXW34_RS13020	COG1794	racemase activity, acting on amino acids and derivatives
EXW34_RS13025	COG1819	glycosyl
EXW34_RS13035	COG0768	penicillin binding
EXW34_RS13040	COG5002	protein histidine kinase activity
EXW34_RS13045	COG0561	phosphatase activity
EXW34_RS13110	COG2124	cytochrome p450
EXW34_RS13160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW34_RS13170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS13175	COG0460	homoserine dehydrogenase
EXW34_RS13195	COG0577	efflux transmembrane transporter activity
EXW34_RS13200	COG1136	(ABC) transporter
EXW34_RS13215	COG0488	(ABC) transporter
EXW34_RS13220	COG0667	Aldo Keto reductase
EXW34_RS13225	COG0583	DNA-binding transcription factor activity
EXW34_RS13235	COG2205	protein histidine kinase activity
EXW34_RS13240	COG0745	RESPONSE REGULATOR receiver
EXW34_RS13250	COG3773	Cell wall hydrolase
EXW34_RS13285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS13300	COG2959	enzyme of heme biosynthesis
EXW34_RS13325	COG3483	tryptophan 2,3-dioxygenase activity
EXW34_RS13330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW34_RS13335	COG3844	kynureninase activity
EXW34_RS13340	COG1309	transcriptional regulator
EXW34_RS13375	COG1349	DNA-binding transcription factor activity
EXW34_RS13395	COG1959	2 iron, 2 sulfur cluster binding
EXW34_RS13415	COG2223	nitrite transmembrane transporter activity
EXW34_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS13430	COG0456	acetyltransferase
EXW34_RS13430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW34_RS13465	COG4176	ABC-type proline glycine betaine transport system permease component
EXW34_RS13470	COG0517	IMP dehydrogenase activity
EXW34_RS13470	COG4175	Glycine betaine
EXW34_RS13495	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW34_RS13500	COG2153	protein acetylation
EXW34_RS13505	COG3397	chitin binding
EXW34_RS13515	COG1819	glycosyl
EXW34_RS13530	COG2205	protein histidine kinase activity
EXW34_RS13535	COG2315	Protein conserved in bacteria
EXW34_RS13580	COG3973	AAA domain
EXW34_RS13595	COG2105	PFAM AIG2 family protein
EXW34_RS13600	COG0514	ATP-dependent DNA helicase (RecQ)
EXW34_RS13625	COG4637	Psort location Cytoplasmic, score
EXW34_RS13645	COG1227	inorganic diphosphatase activity
EXW34_RS13650	COG3397	chitin binding
EXW34_RS13655	COG2318	DinB family
EXW34_RS13670	COG1162	GTPase activity
EXW34_RS13675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW34_RS13680	COG1115	amino acid carrier protein
EXW34_RS13685	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS13690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW34_RS13700	COG3938	Belongs to the proline racemase family
EXW34_RS13705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW34_RS13755	COG1078	dGTPase activity
EXW34_RS13760	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS13775	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW34_RS13780	COG4166	transmembrane transport
EXW34_RS13790	COG4948	Mandelate Racemase Muconate Lactonizing
EXW34_RS13810	COG0667	Aldo Keto reductase
EXW34_RS13855	COG2936	dipeptidyl-peptidase activity
EXW34_RS13865	COG0745	RESPONSE REGULATOR receiver
EXW34_RS13885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW34_RS13890	COG1164	Oligoendopeptidase f
EXW34_RS13910	COG1307	EDD domain protein, DegV family
EXW34_RS13935	COG1335	isochorismatase
EXW34_RS13950	COG2814	Major facilitator Superfamily
EXW34_RS13960	COG1664	Polymer-forming cytoskeletal
EXW34_RS13965	COG0789	Transcriptional regulator
EXW34_RS13970	COG4533	DNA binding
EXW34_RS13975	COG0477	Major facilitator Superfamily
EXW34_RS13975	COG2814	Major facilitator Superfamily
EXW34_RS13995	COG2261	transglycosylase associated protein
EXW34_RS14010	COG2226	methyltransferase
EXW34_RS14045	COG0436	Aminotransferase
EXW34_RS14050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW34_RS14075	COG1131	(ABC) transporter
EXW34_RS14080	COG2188	Transcriptional regulator
EXW34_RS14125	COG0628	permease
EXW34_RS14170	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW34_RS14180	COG0697	spore germination
EXW34_RS14235	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW34_RS14245	COG2814	Major facilitator Superfamily
EXW34_RS14250	COG1368	sulfuric ester hydrolase activity
EXW34_RS14265	COG0488	(ABC) transporter
EXW34_RS14315	COG0582	viral genome integration into host DNA
EXW34_RS14350	COG4974	Belongs to the 'phage' integrase family
EXW34_RS14355	COG2409	Drug exporters of the RND superfamily
EXW34_RS14355	COG1033	growth of symbiont in host cell
EXW34_RS14360	COG1309	transcriptional regulator
EXW34_RS14380	COG0287	Prephenate dehydrogenase
EXW34_RS14395	COG1605	Chorismate mutase
EXW34_RS14395	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW34_RS14430	COG3584	3D domain protein
EXW34_RS14430	COG1388	LysM domain
EXW34_RS14440	COG0346	lactoylglutathione lyase activity
EXW34_RS14445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS14450	COG0431	NADPH-dependent FMN reductase
EXW34_RS14455	COG2610	gluconate transmembrane transporter activity
EXW34_RS14460	COG1024	Enoyl-CoA hydratase
EXW34_RS14470	COG3290	protein histidine kinase activity
EXW34_RS14470	COG3829	transcription factor binding
EXW34_RS14480	COG0579	oxidoreductase
EXW34_RS14485	COG1879	ABC-type sugar transport system periplasmic component
EXW34_RS14500	COG1129	ABC transporter
EXW34_RS14505	COG2390	Transcriptional regulator
EXW34_RS14525	COG2226	methyltransferase
EXW34_RS14540	COG0346	lactoylglutathione lyase activity
EXW34_RS14545	COG2329	Antibiotic biosynthesis monooxygenase
EXW34_RS14565	COG1472	Belongs to the glycosyl hydrolase 3 family
EXW34_RS14570	COG2207	Transcriptional regulator
EXW34_RS14575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS14580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW34_RS14585	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW34_RS14590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW34_RS14595	COG3239	Fatty acid desaturase
EXW34_RS14615	COG3655	Transcriptional regulator
EXW34_RS14660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS14665	COG0346	lactoylglutathione lyase activity
EXW34_RS14690	COG0714	Associated with various cellular activities
EXW34_RS14710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW34_RS14725	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW34_RS14750	COG0714	Associated with various cellular activities
EXW34_RS14760	COG0778	Nitroreductase
EXW34_RS14765	COG1846	Transcriptional regulator
EXW34_RS14785	COG2312	Erythromycin esterase
EXW34_RS14810	COG2207	Transcriptional regulator
EXW34_RS14815	COG0456	acetyltransferase
EXW34_RS14830	COG0697	spore germination
EXW34_RS14835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS14840	COG1671	Belongs to the UPF0178 family
EXW34_RS14855	COG0642	Histidine kinase
EXW34_RS14860	COG0745	RESPONSE REGULATOR receiver
EXW34_RS14865	COG0596	Alpha beta hydrolase
EXW34_RS14875	COG0456	acetyltransferase
EXW34_RS14875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW34_RS14900	COG0730	response to heat
EXW34_RS14910	COG0833	amino acid
EXW34_RS14920	COG4335	DNA alkylation repair
EXW34_RS14950	COG0768	penicillin binding
EXW34_RS14965	COG3104	oligopeptide transport
EXW34_RS14980	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW34_RS14995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW34_RS15000	COG1984	allophanate hydrolase subunit 2
EXW34_RS15005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW34_RS15010	COG1414	Transcriptional regulator
EXW34_RS15025	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS15050	COG0640	Transcriptional regulator
EXW34_RS15060	COG3314	Sporulation integral membrane protein YlbJ
EXW34_RS15080	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW34_RS15095	COG0574	Belongs to the PEP-utilizing enzyme family
EXW34_RS15095	COG3848	Pyruvate phosphate dikinase
EXW34_RS15105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW34_RS15130	COG5002	protein histidine kinase activity
EXW34_RS15135	COG0745	RESPONSE REGULATOR receiver
EXW34_RS15145	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW34_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS15155	COG3347	Dehydrogenase
EXW34_RS15165	COG1070	Carbohydrate kinase
EXW34_RS15170	COG0235	Class ii aldolase
EXW34_RS15180	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW34_RS15190	COG4154	Belongs to the RbsD FucU family
EXW34_RS15205	COG0798	PFAM Bile acid sodium symporter
EXW34_RS15210	COG0346	lactoylglutathione lyase activity
EXW34_RS15215	COG0640	Transcriptional regulator
EXW34_RS15230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW34_RS15230	COG3320	Male sterility
EXW34_RS15235	COG1309	transcriptional regulator
EXW34_RS15240	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS15245	COG1522	sequence-specific DNA binding
EXW34_RS15260	COG0346	lactoylglutathione lyase activity
EXW34_RS15300	COG2226	methyltransferase
EXW34_RS15310	COG2814	Major facilitator Superfamily
EXW34_RS15340	COG0745	RESPONSE REGULATOR receiver
EXW34_RS15345	COG3850	Histidine kinase
EXW34_RS15345	COG5002	protein histidine kinase activity
EXW34_RS15375	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW34_RS15405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW34_RS15435	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW34_RS15455	COG1136	(ABC) transporter
EXW34_RS15460	COG0577	efflux transmembrane transporter activity
EXW34_RS15480	COG3850	Histidine kinase
EXW34_RS15480	COG5002	protein histidine kinase activity
EXW34_RS15495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS15510	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW34_RS15530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW34_RS15570	COG2814	Major facilitator Superfamily
EXW34_RS15585	COG1876	peptidase activity
EXW34_RS15590	COG2843	Capsule synthesis protein
EXW34_RS15605	COG0477	Major facilitator Superfamily
EXW34_RS15620	COG1846	Transcriptional regulator
EXW34_RS15625	COG2814	Major facilitator Superfamily
EXW34_RS15695	COG4187	Peptidase family M20/M25/M40
EXW34_RS15715	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW34_RS15720	COG2031	fatty acid transporter
EXW34_RS15730	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW34_RS15795	COG1288	antiporter activity
EXW34_RS15800	COG2356	endonuclease I
EXW34_RS15805	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW34_RS15815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW34_RS15830	COG0469	pyruvate kinase activity
EXW34_RS15835	COG1785	Belongs to the alkaline phosphatase family
EXW34_RS15840	COG0778	Nitroreductase
EXW34_RS15845	COG1733	regulation of RNA biosynthetic process
EXW34_RS15860	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS15870	COG1131	(ABC) transporter
EXW34_RS15900	COG1595	DNA-templated transcription, initiation
EXW34_RS15915	COG1011	Hydrolase
EXW34_RS15920	COG2365	Tyrosine phosphatase family
EXW34_RS15945	COG0346	lactoylglutathione lyase activity
EXW34_RS15950	COG1940	carbohydrate kinase activity
EXW34_RS15955	COG0738	Major facilitator superfamily
EXW34_RS15960	COG0110	maltose O-acetyltransferase activity
EXW34_RS15975	COG0628	permease
EXW34_RS15980	COG2261	transglycosylase associated protein
EXW34_RS15995	COG1720	tRNA m6t6A37 methyltransferase activity
EXW34_RS16000	COG0500	methyltransferase
EXW34_RS16010	COG0477	Major facilitator Superfamily
EXW34_RS16035	COG1253	flavin adenine dinucleotide binding
EXW34_RS16040	COG0789	Transcriptional regulator
EXW34_RS16050	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW34_RS16075	COG0697	spore germination
EXW34_RS16080	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW34_RS16085	COG3813	Protein conserved in bacteria
EXW34_RS16090	COG4702	Belongs to the UPF0303 family
EXW34_RS16100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS16115	COG0494	nUDIX hydrolase
EXW34_RS16130	COG0384	phenazine biosynthesis protein PhzF
EXW34_RS16140	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS16145	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW34_RS16150	COG1733	regulation of RNA biosynthetic process
EXW34_RS16165	COG1191	sigma factor activity
EXW34_RS16185	COG1876	peptidase activity
EXW34_RS16215	COG0741	lytic transglycosylase activity
EXW34_RS16240	COG4585	Histidine kinase
EXW34_RS16245	COG2197	response regulator
EXW34_RS16280	COG5002	protein histidine kinase activity
EXW34_RS16285	COG0745	RESPONSE REGULATOR receiver
EXW34_RS16325	COG0814	amino acid
EXW34_RS16350	COG1151	hydroxylamine reductase activity
EXW34_RS16380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS16390	COG2072	flavoprotein involved in K transport
EXW34_RS16435	COG1695	Transcriptional regulator
EXW34_RS16440	COG0604	alcohol dehydrogenase
EXW34_RS16445	COG1113	amino acid transport
EXW34_RS16455	COG2814	Major facilitator Superfamily
EXW34_RS16465	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW34_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS16480	COG0534	Mate efflux family protein
EXW34_RS16485	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS16490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW34_RS16505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW34_RS16510	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW34_RS16530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS16535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS16540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS16545	COG3739	integral membrane protein
EXW34_RS16570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS16575	COG0583	DNA-binding transcription factor activity
EXW34_RS16600	COG1193	negative regulation of DNA recombination
EXW34_RS16610	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW34_RS16615	COG1164	Oligoendopeptidase f
EXW34_RS16620	COG2957	Belongs to the agmatine deiminase family
EXW34_RS16640	COG3781	membrane
EXW34_RS16655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS16735	COG0640	Transcriptional regulator
EXW34_RS16740	COG0604	alcohol dehydrogenase
EXW34_RS16745	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW34_RS16750	COG0457	Tetratricopeptide repeat
EXW34_RS16760	COG2808	Putative FMN-binding domain
EXW34_RS16790	COG1285	pathogenesis
EXW34_RS16800	COG2514	catechol 2,3-dioxygenase activity
EXW34_RS16805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS16810	COG1126	abc transporter atp-binding protein
EXW34_RS16815	COG0765	amino acid transport
EXW34_RS16820	COG2720	vancomycin resistance protein
EXW34_RS16845	COG1278	Cold shock
EXW34_RS16855	COG0716	FMN binding
EXW34_RS16865	COG0494	nUDIX hydrolase
EXW34_RS16885	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS16895	COG0165	Argininosuccinate lyase
EXW34_RS16910	COG4145	pantothenate transmembrane transporter activity
EXW34_RS16920	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS16925	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS16935	COG1657	PFAM Prenyltransferase squalene oxidase
EXW34_RS16940	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW34_RS16945	COG2962	Rard protein
EXW34_RS16950	COG3326	Membrane
EXW34_RS16955	COG0531	amino acid
EXW34_RS16985	COG2226	methyltransferase
EXW34_RS16990	COG4166	transmembrane transport
EXW34_RS16995	COG4166	transmembrane transport
EXW34_RS17000	COG4166	transmembrane transport
EXW34_RS17005	COG1316	TRANSCRIPTIONal
EXW34_RS17015	COG1595	DNA-templated transcription, initiation
EXW34_RS17025	COG1131	(ABC) transporter
EXW34_RS17045	COG0673	inositol 2-dehydrogenase activity
EXW34_RS17050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW34_RS17055	COG0187	DNA topoisomerase II activity
EXW34_RS17060	COG1832	CoA-binding protein
EXW34_RS17065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW34_RS17070	COG0745	RESPONSE REGULATOR receiver
EXW34_RS17080	COG1328	CTP reductase activity
EXW34_RS17080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW34_RS17090	COG4841	protein insertion into membrane
EXW34_RS17095	COG0824	Thioesterase
EXW34_RS17120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS17135	COG2274	protein secretion by the type I secretion system
EXW34_RS17140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW34_RS17170	COG2211	Major facilitator Superfamily
EXW34_RS17180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW34_RS17195	COG0183	Belongs to the thiolase family
EXW34_RS17200	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS17205	COG1268	BioY protein
EXW34_RS17210	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS17215	COG1396	sequence-specific DNA binding
EXW34_RS17255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS17265	COG5002	protein histidine kinase activity
EXW34_RS17275	COG0400	carboxylic ester hydrolase activity
EXW34_RS17280	COG0346	lactoylglutathione lyase activity
EXW34_RS17285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW34_RS17290	COG0069	glutamate synthase activity
EXW34_RS17295	COG1902	pentaerythritol trinitrate reductase activity
EXW34_RS17305	COG1329	Transcriptional regulator
EXW34_RS17310	COG0010	Belongs to the arginase family
EXW34_RS17320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW34_RS17325	COG2986	histidine ammonia-lyase
EXW34_RS17335	COG2226	methyltransferase
EXW34_RS17360	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW34_RS17365	COG0785	Cytochrome C biogenesis protein
EXW34_RS17375	COG1473	amidohydrolase
EXW34_RS17380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW34_RS17385	COG1131	(ABC) transporter
EXW34_RS17395	COG0583	DNA-binding transcription factor activity
EXW34_RS17405	COG1346	cytolysis
EXW34_RS17420	COG0730	response to heat
EXW34_RS17430	COG3409	Peptidoglycan-binding domain 1 protein
EXW34_RS17430	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS17450	COG1132	(ABC) transporter
EXW34_RS17455	COG1132	(ABC) transporter
EXW34_RS17460	COG3763	UPF0154 protein
EXW34_RS17480	COG3639	organic phosphonate transmembrane transporter activity
EXW34_RS17490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS17495	COG0737	Belongs to the 5'-nucleotidase family
EXW34_RS17505	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW34_RS17510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW34_RS17525	COG1695	Transcriptional regulator
EXW34_RS17530	COG0174	glutamine synthetase
EXW34_RS17535	COG0789	Transcriptional regulator
EXW34_RS17540	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW34_RS17545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW34_RS17550	COG2860	membrane
EXW34_RS17560	COG0464	growth
EXW34_RS17580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW34_RS17590	COG1388	LysM domain
EXW34_RS17590	COG3584	3D domain protein
EXW34_RS17595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW34_RS17595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW34_RS17595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW34_RS17600	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW34_RS17605	COG1349	DNA-binding transcription factor activity
EXW34_RS17610	COG1979	alcohol dehydrogenase
EXW34_RS17615	COG2322	membrane
EXW34_RS17625	COG1113	amino acid transport
EXW34_RS17635	COG1473	amidohydrolase
EXW34_RS17640	COG1408	metallophosphoesterase
EXW34_RS17645	COG2116	formate transmembrane transporter activity
EXW34_RS17660	COG2217	Heavy metal translocating P-type atpase
EXW34_RS17665	COG2608	mercury ion transmembrane transporter activity
EXW34_RS17670	COG1937	Protein conserved in bacteria
EXW34_RS17690	COG2819	hydrolase of the alpha beta superfamily
EXW34_RS17695	COG1120	ATPase activity
EXW34_RS17700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS17705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS17710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS17715	COG0708	Exodeoxyribonuclease III
EXW34_RS17720	COG2169	Transcriptional regulator
EXW34_RS17725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW34_RS17730	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW34_RS17735	COG2706	6-phosphogluconolactonase activity
EXW34_RS17740	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW34_RS17745	COG2364	Membrane
EXW34_RS17755	COG0346	lactoylglutathione lyase activity
EXW34_RS17760	COG3300	MHYT domain
EXW34_RS17760	COG5001	Diguanylate cyclase
EXW34_RS17805	COG1346	cytolysis
EXW34_RS17815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS17820	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW34_RS17820	COG0596	Alpha beta hydrolase
EXW34_RS17825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW34_RS17835	COG2188	Transcriptional regulator
EXW34_RS17840	COG2723	6-phospho-beta-galactosidase activity
EXW34_RS17845	COG0840	transmembrane signaling receptor activity
EXW34_RS17855	COG1368	sulfuric ester hydrolase activity
EXW34_RS17860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW34_RS17870	COG2723	6-phospho-beta-galactosidase activity
EXW34_RS17875	COG1263	PTS System
EXW34_RS17875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS17875	COG2190	(PTS) system
EXW34_RS17880	COG3547	Transposase (IS116 IS110 IS902 family)
EXW34_RS17885	COG3711	transcriptional antiterminator
EXW34_RS17895	COG0640	Transcriptional regulator
EXW34_RS17900	COG0697	spore germination
EXW34_RS17905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS17910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW34_RS17915	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW34_RS17925	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW34_RS17930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW34_RS17935	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW34_RS17940	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW34_RS17940	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW34_RS17950	COG2359	stage V sporulation protein S
EXW34_RS17955	COG1692	metallophosphoesterase
EXW34_RS17960	COG1418	mRNA catabolic process
EXW34_RS17965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW34_RS17970	COG1546	Belongs to the CinA family
EXW34_RS17970	COG1058	Belongs to the CinA family
EXW34_RS17975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW34_RS17980	COG1426	Protein conserved in bacteria
EXW34_RS17995	COG0300	oxidoreductase activity
EXW34_RS18000	COG0612	Peptidase, M16
EXW34_RS18005	COG0612	Peptidase, M16
EXW34_RS18010	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW34_RS18015	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW34_RS18020	COG3845	ABC transporter
EXW34_RS18025	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW34_RS18030	COG2188	Transcriptional regulator
EXW34_RS18035	COG1674	ftsk spoiiie
EXW34_RS18045	COG0740	serine-type endopeptidase activity
EXW34_RS18050	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW34_RS18060	COG0527	aspartate kinase activity
EXW34_RS18065	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW34_RS18110	COG4824	toxin secretion phage lysis holin
EXW34_RS18220	COG0582	viral genome integration into host DNA
EXW34_RS18255	COG0305	Participates in initiation and elongation during chromosome replication
EXW34_RS18315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW34_RS18320	COG1873	PFAM PRC-barrel domain
EXW34_RS18325	COG0612	Peptidase, M16
EXW34_RS18330	COG0726	polysaccharide deacetylase
EXW34_RS18335	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW34_RS18345	COG0196	riboflavin kinase activity
EXW34_RS18355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW34_RS18360	COG1550	Protein conserved in bacteria
EXW34_RS18365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW34_RS18370	COG1358	cellular component organization or biogenesis
EXW34_RS18375	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW34_RS18380	COG0195	Participates in both transcription termination and antitermination
EXW34_RS18385	COG0779	Required for maturation of 30S ribosomal subunits
EXW34_RS18395	COG0442	prolyl-tRNA aminoacylation
EXW34_RS18400	COG0750	zinc metalloprotease
EXW34_RS18410	COG4589	Belongs to the CDS family
EXW34_RS18420	COG0233	cytoplasmic translational termination
EXW34_RS18425	COG0528	UMP kinase activity
EXW34_RS18430	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW34_RS18435	COG0052	Belongs to the universal ribosomal protein uS2 family
EXW34_RS18440	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW34_RS18445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW34_RS18450	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW34_RS18455	COG4974	Belongs to the 'phage' integrase family
EXW34_RS18460	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW34_RS18465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW34_RS18470	COG0758	DNA mediated transformation
EXW34_RS18475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW34_RS18480	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW34_RS18485	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW34_RS18500	COG0335	large ribosomal subunit rRNA binding
EXW34_RS18505	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW34_RS18510	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW34_RS18515	COG1837	Belongs to the UPF0109 family
EXW34_RS18525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW34_RS18535	COG0552	protein localization to endoplasmic reticulum
EXW34_RS18540	COG1196	nuclear chromosome segregation
EXW34_RS18545	COG0571	ribonuclease III activity
EXW34_RS18550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW34_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS18560	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW34_RS18565	COG0416	fatty acid biosynthetic process
EXW34_RS18570	COG1349	DNA-binding transcription factor activity
EXW34_RS18570	COG2050	protein possibly involved in aromatic compounds catabolism
EXW34_RS18575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW34_RS18580	COG1461	Dihydroxyacetone kinase
EXW34_RS18585	COG1302	Protein conserved in bacteria
EXW34_RS18600	COG1564	THIamine pyrophosphokinase
EXW34_RS18605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW34_RS18615	COG2815	serine threonine protein kinase
EXW34_RS18615	COG0515	serine threonine protein kinase
EXW34_RS18620	COG0631	protein serine/threonine phosphatase activity
EXW34_RS18625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW34_RS18630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW34_RS18630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW34_RS18635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW34_RS18640	COG0242	peptide deformylase activity
EXW34_RS18645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW34_RS18650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW34_RS18655	COG1758	RNA polymerase activity
EXW34_RS18670	COG1561	YicC-like family, N-terminal region
EXW34_RS18675	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW34_RS18685	COG0006	proline dipeptidase activity
EXW34_RS18705	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW34_RS18730	COG0167	dihydroorotate dehydrogenase activity
EXW34_RS18735	COG0543	2 iron, 2 sulfur cluster binding
EXW34_RS18740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW34_RS18750	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW34_RS18755	COG0540	Belongs to the ATCase OTCase family
EXW34_RS18765	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW34_RS18770	COG0564	pseudouridine synthase activity
EXW34_RS18775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW34_RS18785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW34_RS18790	COG3599	regulation of cell shape
EXW34_RS18795	COG2302	S4 RNA-binding domain
EXW34_RS18800	COG0762	integral membrane protein
EXW34_RS18805	COG1799	cell septum assembly
EXW34_RS18810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW34_RS18820	COG1873	PFAM PRC-barrel domain
EXW34_RS18825	COG1191	sigma factor activity
EXW34_RS18830	COG1191	sigma factor activity
EXW34_RS18840	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW34_RS18845	COG0849	cell division
EXW34_RS18850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW34_RS18865	COG0772	Belongs to the SEDS family
EXW34_RS18870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW34_RS18875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW34_RS18880	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW34_RS18885	COG0768	penicillin binding
EXW34_RS18890	COG0768	penicillin binding
EXW34_RS18900	COG0275	rRNA processing
EXW34_RS18905	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW34_RS18910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW34_RS18915	COG0454	-acetyltransferase
EXW34_RS18925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW34_RS18930	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW34_RS18935	COG1323	Belongs to the UPF0348 family
EXW34_RS18940	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW34_RS18945	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW34_RS18950	COG3314	Sporulation integral membrane protein YlbJ
EXW34_RS18955	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EXW34_RS18960	COG0742	ribosomal rna small subunit methyltransferase
EXW34_RS18970	COG4471	UPF0298 protein
EXW34_RS18975	COG3679	Belongs to the UPF0342 family
EXW34_RS18980	COG0406	alpha-ribazole phosphatase activity
EXW34_RS18995	COG2340	Cysteine-rich secretory protein family
EXW34_RS19005	COG3336	cytochrome c oxidase
EXW34_RS19030	COG0109	protoheme IX farnesyltransferase activity
EXW34_RS19035	COG1612	heme a metabolic process
EXW34_RS19040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW34_RS19045	COG0772	Belongs to the SEDS family
EXW34_RS19050	COG4838	Belongs to the UPF0358 family
EXW34_RS19055	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW34_RS19060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW34_RS19070	COG4896	Protein conserved in bacteria
EXW34_RS19085	COG1217	gtp-binding protein TYPA
EXW34_RS19095	COG0483	inositol monophosphate 1-phosphatase activity
EXW34_RS19105	COG4493	Belongs to the UPF0637 family
EXW34_RS19110	COG4476	Belongs to the UPF0223 family
EXW34_RS19115	COG1982	Orn Lys Arg decarboxylase major
EXW34_RS19160	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW34_RS19165	COG0022	dehydrogenase e1 component
EXW34_RS19170	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW34_RS19185	COG0561	phosphatase activity
EXW34_RS19190	COG5503	Protein of unknown function (DUF1447)
EXW34_RS19195	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW34_RS19200	COG0569	domain protein
EXW34_RS19210	COG1473	amidohydrolase
EXW34_RS19215	COG2171	N-acyltransferase activity
EXW34_RS19220	COG0583	DNA-binding transcription factor activity
EXW34_RS19225	COG0517	IMP dehydrogenase activity
EXW34_RS19235	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW34_RS19245	COG4703	Protein of unknown function (DUF1797)
EXW34_RS19260	COG2200	EAL domain
EXW34_RS19265	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS19270	COG1408	metallophosphoesterase
EXW34_RS19315	COG2814	Major facilitator Superfamily
EXW34_RS19325	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW34_RS19335	COG3209	COG3209 Rhs family protein
EXW34_RS19345	COG2205	protein histidine kinase activity
EXW34_RS19355	COG0436	Aminotransferase
EXW34_RS19360	COG1609	Transcriptional regulator
EXW34_RS19365	COG3833	ABC-type maltose transport systems, permease component
EXW34_RS19370	COG1175	transmembrane transport
EXW34_RS19375	COG2182	Extracellular solute-binding protein
EXW34_RS19385	COG0366	Alpha amylase catalytic
EXW34_RS19390	COG3842	ATPase activity
EXW34_RS19430	COG0183	Belongs to the thiolase family
EXW34_RS19465	COG1695	Transcriptional regulator
EXW34_RS19470	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS19480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW34_RS19485	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW34_RS19490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW34_RS19495	COG0436	Aminotransferase
EXW34_RS19500	COG1850	ribulose-bisphosphate carboxylase activity
EXW34_RS19505	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW34_RS19510	COG0235	Class ii aldolase
EXW34_RS19515	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW34_RS19535	COG2084	Dehydrogenase
EXW34_RS19545	COG2199	diguanylate cyclase activity
EXW34_RS19550	COG0778	Nitroreductase
EXW34_RS19575	COG1263	PTS System
EXW34_RS19575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW34_RS19575	COG2190	(PTS) system
EXW34_RS19580	COG3711	transcriptional antiterminator
EXW34_RS19590	COG2188	Transcriptional regulator
EXW34_RS19595	COG0363	glucosamine-6-phosphate deaminase activity
EXW34_RS19600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW34_RS19610	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW34_RS19615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW34_RS19625	COG1547	Domain of unknown function (DUF309)
EXW34_RS19635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW34_RS19640	COG4086	secreted protein
EXW34_RS19645	COG0561	phosphatase activity
EXW34_RS19650	COG0697	spore germination
EXW34_RS19665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW34_RS19705	COG1686	Belongs to the peptidase S11 family
EXW34_RS19710	COG1725	Transcriptional regulator
EXW34_RS19715	COG1131	(ABC) transporter
EXW34_RS19735	COG1846	Transcriptional regulator
EXW34_RS19750	COG0598	Magnesium transport protein CorA
EXW34_RS19765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW34_RS19775	COG4974	Belongs to the 'phage' integrase family
EXW34_RS19785	COG0735	belongs to the Fur family
EXW34_RS19790	COG1300	Membrane
EXW34_RS19810	COG0667	Aldo Keto reductase
EXW34_RS19815	COG0656	L-ascorbic acid biosynthetic process
EXW34_RS19820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW34_RS19820	COG0456	acetyltransferase
EXW34_RS19830	COG0737	Belongs to the 5'-nucleotidase family
EXW34_RS19830	COG1525	nuclease
EXW34_RS19830	COG4085	toxin activity
EXW34_RS19835	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW34_RS19845	COG0596	Alpha beta hydrolase
EXW34_RS19850	COG2056	Na+-H+ antiporter family
EXW34_RS19855	COG1609	Transcriptional regulator
EXW34_RS19860	COG0456	acetyltransferase
EXW34_RS19865	COG1073	alpha beta
EXW34_RS19880	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW34_RS19880	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW34_RS19885	COG0307	riboflavin synthase, alpha
EXW34_RS19890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW34_RS19890	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW34_RS19905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW34_RS19910	COG4106	trans-aconitate 2-methyltransferase activity
EXW34_RS19915	COG1073	alpha beta
EXW34_RS19915	COG2226	methyltransferase
EXW34_RS19920	COG0156	8-amino-7-oxononanoate synthase activity
EXW34_RS19930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW34_RS19940	COG1757	Na H antiporter
EXW34_RS19945	COG0737	Belongs to the 5'-nucleotidase family
EXW34_RS19955	COG1522	sequence-specific DNA binding
EXW34_RS19995	COG0666	response to abiotic stimulus
EXW34_RS20025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW34_RS20030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EXW34_RS20040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW34_RS20050	COG0300	oxidoreductase activity
EXW34_RS20055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS20060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW34_RS20065	COG1760	l-serine dehydratase
EXW34_RS20070	COG1760	l-serine dehydratase
EXW34_RS20080	COG1234	tRNA 3'-trailer cleavage
EXW34_RS20105	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW34_RS20110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS20125	COG1376	ErfK ybiS ycfS ynhG family protein
EXW34_RS20130	COG4129	membrane
EXW34_RS20135	COG1126	abc transporter atp-binding protein
EXW34_RS20140	COG0765	amino acid transport
EXW34_RS20145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW34_RS20160	COG2816	NAD+ diphosphatase activity
EXW34_RS20165	COG2323	membrane
EXW34_RS20170	COG0772	Belongs to the SEDS family
EXW34_RS20175	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW34_RS20180	COG0022	dehydrogenase e1 component
EXW34_RS20185	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW34_RS20190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW34_RS20195	COG3426	butyrate kinase activity
EXW34_RS20205	COG0280	phosphate acetyltransferase
EXW34_RS20210	COG3829	transcription factor binding
EXW34_RS20210	COG3290	protein histidine kinase activity
EXW34_RS20220	COG0584	glycerophosphoryl diester phosphodiesterase
EXW34_RS20225	COG3093	addiction module antidote protein HigA
EXW34_RS20240	COG0745	RESPONSE REGULATOR receiver
EXW34_RS20245	COG0750	zinc metalloprotease
EXW34_RS20250	COG0497	DNA recombination
EXW34_RS20255	COG1438	arginine binding
EXW34_RS20260	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW34_RS20265	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW34_RS20270	COG0142	geranyltranstransferase activity
EXW34_RS20275	COG1722	exodeoxyribonuclease VII activity
EXW34_RS20280	COG1570	exodeoxyribonuclease VII activity
EXW34_RS20285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW34_RS20290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW34_RS20295	COG1302	Protein conserved in bacteria
EXW34_RS20300	COG0439	Biotin carboxylase
EXW34_RS20305	COG0511	ligase activity, forming carbon-carbon bonds
EXW34_RS20350	COG3854	ATPases associated with a variety of cellular activities
EXW34_RS20370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW34_RS20375	COG0006	proline dipeptidase activity
EXW34_RS20380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW34_RS20390	COG3872	metal-dependent enzyme
EXW34_RS20400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW34_RS20405	COG1321	iron dependent repressor
EXW34_RS20435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS20445	COG1609	Transcriptional regulator
EXW34_RS20455	COG2076	Multidrug Resistance protein
EXW34_RS20460	COG2076	Multidrug Resistance protein
EXW34_RS20500	COG1725	Transcriptional regulator
EXW34_RS20515	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW34_RS20520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW34_RS20525	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW34_RS20530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW34_RS20560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW34_RS20585	COG4970	Tfp pilus assembly protein FimT
EXW34_RS20595	COG1459	type II secretion system
EXW34_RS20600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW34_RS20655	COG1410	methionine synthase
EXW34_RS20655	COG0646	methionine synthase
EXW34_RS20660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW34_RS20660	COG0646	methionine synthase
EXW34_RS20665	COG0626	cystathionine gamma-synthase activity
EXW34_RS20670	COG0626	cystathionine gamma-synthase activity
EXW34_RS20685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS20695	COG1940	carbohydrate kinase activity
EXW34_RS20700	COG4483	Protein conserved in bacteria
EXW34_RS20705	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW34_RS20710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW34_RS20715	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW34_RS20720	COG0704	Plays a role in the regulation of phosphate uptake
EXW34_RS20735	COG0581	inorganic phosphate transmembrane transporter activity
EXW34_RS20740	COG0573	inorganic phosphate transmembrane transporter activity
EXW34_RS20745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW34_RS20750	COG0768	penicillin binding
EXW34_RS20755	COG0477	Major facilitator Superfamily
EXW34_RS20760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW34_RS20780	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW34_RS20785	COG0735	belongs to the Fur family
EXW34_RS20790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW34_RS20795	COG1121	(ABC) transporter
EXW34_RS20800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS20810	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW34_RS20825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW34_RS20830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW34_RS20835	COG2384	SAM-dependent methyltransferase
EXW34_RS20840	COG2010	Cytochrome c
EXW34_RS20845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW34_RS20850	COG0358	DNA primase activity
EXW34_RS20860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW34_RS20865	COG0517	IMP dehydrogenase activity
EXW34_RS20870	COG1381	Involved in DNA repair and RecF pathway recombination
EXW34_RS20880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW34_RS20885	COG0295	cytidine deaminase activity
EXW34_RS20890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW34_RS20895	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW34_RS20900	COG1480	7TM receptor with intracellular HD hydrolase
EXW34_RS20905	COG1702	phosphate starvation-inducible protein PhoH
EXW34_RS20920	COG1610	YqeY-like protein
EXW34_RS20925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW34_RS20930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW34_RS20935	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW34_RS20945	COG0484	heat shock protein binding
EXW34_RS20950	COG0443	Heat shock 70 kDa protein
EXW34_RS20960	COG1420	regulation of RNA biosynthetic process
EXW34_RS20965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW34_RS20970	COG1733	regulation of RNA biosynthetic process
EXW34_RS20975	COG0481	GTPase activity
EXW34_RS20985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW34_RS20990	COG0268	Binds directly to 16S ribosomal RNA
EXW34_RS20995	COG1466	dna polymerase III delta subunit
EXW34_RS21010	COG2131	deaminase
EXW34_RS21020	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW34_RS21025	COG2226	methyltransferase
EXW34_RS21030	COG0799	negative regulation of ribosome biogenesis
EXW34_RS21035	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW34_RS21040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW34_RS21045	COG1534	Rna-binding protein
EXW34_RS21050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW34_RS21055	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW34_RS21060	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW34_RS21070	COG0688	phosphatidylethanolamine metabolic process
EXW34_RS21080	COG1595	DNA-templated transcription, initiation
EXW34_RS21085	COG2357	RelA SpoT domain protein
EXW34_RS21095	COG1785	Belongs to the alkaline phosphatase family
EXW34_RS21105	COG2267	carboxylic ester hydrolase activity
EXW34_RS21140	COG1404	Belongs to the peptidase S8 family
EXW34_RS21145	COG3186	Phenylalanine-4-hydroxylase
EXW34_RS21150	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW34_RS21155	COG2514	catechol 2,3-dioxygenase activity
EXW34_RS21160	COG2259	Doxx family
EXW34_RS21200	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS21210	COG1454	alcohol dehydrogenase
EXW34_RS21210	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS21215	COG0626	cystathionine gamma-synthase activity
EXW34_RS21220	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW34_RS21225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW34_RS21230	COG2226	methyltransferase
EXW34_RS21245	COG0768	penicillin binding
EXW34_RS21250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW34_RS21255	COG0572	uridine kinase
EXW34_RS21260	COG0826	peptidase U32
EXW34_RS21265	COG0826	peptidase U32
EXW34_RS21270	COG4122	O-methyltransferase activity
EXW34_RS21275	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW34_RS21285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW34_RS21290	COG4472	Bacterial protein of unknown function (DUF965)
EXW34_RS21295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW34_RS21305	COG0628	permease
EXW34_RS21325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW34_RS21335	COG0482	sulfurtransferase activity
EXW34_RS21340	COG1104	cysteine desulfurase activity
EXW34_RS21345	COG1959	2 iron, 2 sulfur cluster binding
EXW34_RS21350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW34_RS21360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW34_RS21365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW34_RS21380	COG1490	D-aminoacyl-tRNA deacylase activity
EXW34_RS21385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW34_RS21390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW34_RS21395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW34_RS21395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW34_RS21400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW34_RS21405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW34_RS21405	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW34_RS21415	COG2244	polysaccharide biosynthetic process
EXW34_RS21420	COG2323	membrane
EXW34_RS21430	COG1862	Preprotein translocase
EXW34_RS21435	COG0343	queuine tRNA-ribosyltransferase activity
EXW34_RS21440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW34_RS21450	COG2255	four-way junction helicase activity
EXW34_RS21455	COG0632	four-way junction helicase activity
EXW34_RS21460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW34_RS21485	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW34_RS21490	COG0157	Belongs to the NadC ModD family
EXW34_RS21495	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW34_RS21500	COG1104	cysteine desulfurase activity
EXW34_RS21505	COG1827	regulation of RNA biosynthetic process
EXW34_RS21510	COG2258	MOSC domain
EXW34_RS21515	COG0077	Prephenate dehydratase
EXW34_RS21520	COG0577	efflux transmembrane transporter activity
EXW34_RS21525	COG0577	efflux transmembrane transporter activity
EXW34_RS21530	COG1136	(ABC) transporter
EXW34_RS21535	COG5002	protein histidine kinase activity
EXW34_RS21540	COG0745	RESPONSE REGULATOR receiver
EXW34_RS21545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW34_RS21550	COG3290	protein histidine kinase activity
EXW34_RS21560	COG2868	ribosomal protein
EXW34_RS21570	COG1530	ribonuclease E activity
EXW34_RS21575	COG1994	Peptidase M50
EXW34_RS21580	COG0739	heme binding
EXW34_RS21585	COG2894	cell division
EXW34_RS21590	COG0850	regulation of cytokinetic process
EXW34_RS21605	COG1077	Cell shape determining protein MreB Mrl
EXW34_RS21610	COG2003	Belongs to the UPF0758 family
EXW34_RS21615	COG0424	maF-like protein
EXW34_RS21625	COG0285	dihydrofolate synthase activity
EXW34_RS21640	COG1388	LysM domain
EXW34_RS21645	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW34_RS21650	COG0113	porphobilinogen synthase activity
EXW34_RS21655	COG1587	Uroporphyrinogen-III synthase
EXW34_RS21660	COG0181	hydroxymethylbilane synthase activity
EXW34_RS21665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW34_RS21670	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW34_RS21675	COG1846	Transcriptional regulator
EXW34_RS21680	COG1764	response to oxidative stress
EXW34_RS21685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW34_RS21695	COG0470	DNA polymerase III
EXW34_RS21695	COG1067	ATP-dependent peptidase activity
EXW34_RS21705	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW34_RS21735	COG0622	Phosphoesterase
EXW34_RS21745	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW34_RS21750	COG5401	PFAM Sporulation and spore germination
EXW34_RS21760	COG2197	response regulator
EXW34_RS21765	COG2233	PERMEase
EXW34_RS21770	COG0402	S-adenosylhomocysteine deaminase activity
EXW34_RS21775	COG1983	PspC domain protein
EXW34_RS21780	COG1396	sequence-specific DNA binding
EXW34_RS21785	COG0697	spore germination
EXW34_RS21795	COG1959	2 iron, 2 sulfur cluster binding
EXW34_RS21800	COG1668	transmembrane transport
EXW34_RS21805	COG4152	abc transporter atp-binding protein
EXW34_RS21810	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW34_RS21815	COG1360	Flagellar Motor Protein
EXW34_RS21825	COG1876	peptidase activity
EXW34_RS21830	COG0824	Thioesterase
EXW34_RS21835	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW34_RS21840	COG1053	succinate dehydrogenase
EXW34_RS21845	COG2009	succinate dehydrogenase
EXW34_RS21850	COG1719	4-vinyl reductase, 4VR
EXW34_RS21855	COG0322	excinuclease ABC activity
EXW34_RS21860	COG3118	belongs to the thioredoxin family
EXW34_RS21865	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW34_RS21870	COG2086	electron transfer activity
EXW34_RS21875	COG1024	Enoyl-CoA hydratase
EXW34_RS21880	COG1309	transcriptional regulator
EXW34_RS21885	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS21905	COG2318	DinB family
EXW34_RS21935	COG1131	(ABC) transporter
EXW34_RS21940	COG2205	protein histidine kinase activity
EXW34_RS21945	COG0745	RESPONSE REGULATOR receiver
EXW34_RS21955	COG4895	conserved protein (DUF2196)
EXW34_RS21960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW34_RS21970	COG2329	Antibiotic biosynthesis monooxygenase
EXW34_RS21975	COG4509	Sortase family
EXW34_RS21980	COG1120	ATPase activity
EXW34_RS21995	COG5386	Cell surface protein
EXW34_RS22000	COG5386	Cell surface protein
EXW34_RS22005	COG1114	Component of the transport system for branched-chain amino acids
EXW34_RS22015	COG1193	negative regulation of DNA recombination
EXW34_RS22020	COG1796	DNA polymerase
EXW34_RS22020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW34_RS22025	COG1286	toxin biosynthetic process
EXW34_RS22030	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW34_RS22035	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW34_RS22065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW34_RS22070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW34_RS22080	COG1418	mRNA catabolic process
EXW34_RS22110	COG2814	Major facilitator Superfamily
EXW34_RS22115	COG1566	PFAM secretion protein HlyD family protein
EXW34_RS22120	COG1309	transcriptional regulator
EXW34_RS22125	COG1363	Peptidase, m42
EXW34_RS22135	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW34_RS22150	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW34_RS22160	COG1484	DNA-dependent DNA replication
EXW34_RS22165	COG3611	Membrane attachment protein
EXW34_RS22170	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW34_RS22175	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW34_RS22180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW34_RS22185	COG0237	dephospho-CoA kinase activity
EXW34_RS22190	COG1971	Probably functions as a manganese efflux pump
EXW34_RS22200	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW34_RS22200	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW34_RS22205	COG5002	protein histidine kinase activity
EXW34_RS22210	COG0745	RESPONSE REGULATOR receiver
EXW34_RS22225	COG0039	L-malate dehydrogenase activity
EXW34_RS22230	COG0538	isocitrate dehydrogenase activity
EXW34_RS22235	COG0372	Belongs to the citrate synthase family
EXW34_RS22245	COG0628	permease
EXW34_RS22250	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW34_RS22260	COG0205	6-phosphofructokinase activity
EXW34_RS22270	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW34_RS22275	COG1725	Transcriptional regulator
EXW34_RS22280	COG0281	malic enzyme
EXW34_RS22285	COG0587	DNA-directed DNA polymerase activity
EXW34_RS22300	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW34_RS22315	COG4109	DRTGG domain
EXW34_RS22325	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW34_RS22330	COG0006	proline dipeptidase activity
EXW34_RS22360	COG0662	Cupin 2, conserved barrel domain protein
EXW34_RS22375	COG1028	Short-chain dehydrogenase reductase Sdr
EXW34_RS22380	COG0589	response to stress
EXW34_RS22410	COG0137	argininosuccinate synthase activity
EXW34_RS22425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS22445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW34_RS22450	COG0827	DNA restriction-modification system
EXW34_RS22455	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW34_RS22460	COG3874	Sporulation protein YtfJ
EXW34_RS22475	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW34_RS22485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW34_RS22500	COG1104	cysteine desulfurase activity
EXW34_RS22505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW34_RS22515	COG1309	transcriptional regulator
EXW34_RS22520	COG1956	GAF domain-containing protein
EXW34_RS22525	COG0626	cystathionine gamma-synthase activity
EXW34_RS22530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW34_RS22575	COG1595	DNA-templated transcription, initiation
EXW34_RS22585	COG0110	maltose O-acetyltransferase activity
EXW34_RS22590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW34_RS22595	COG0454	-acetyltransferase
EXW34_RS22600	COG0517	IMP dehydrogenase activity
EXW34_RS22605	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW34_RS22610	COG2267	carboxylic ester hydrolase activity
EXW34_RS22620	COG0745	RESPONSE REGULATOR receiver
EXW34_RS22625	COG5002	protein histidine kinase activity
EXW34_RS22630	COG0666	response to abiotic stimulus
EXW34_RS22640	COG1970	mechanosensitive ion channel activity
EXW34_RS22660	COG1609	Transcriptional regulator
EXW34_RS22670	COG4851	CamS sex pheromone cAM373 precursor
EXW34_RS22675	COG3118	belongs to the thioredoxin family
EXW34_RS22685	COG2309	aminopeptidase activity
EXW34_RS22715	COG1695	Transcriptional regulator
EXW34_RS22725	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW34_RS22735	COG1674	ftsk spoiiie
EXW34_RS22750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW34_RS22755	COG4848	Belongs to the UPF0354 family
EXW34_RS22760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS22765	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW34_RS22770	COG1363	Peptidase, m42
EXW34_RS22780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS22785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW34_RS22795	COG0510	thiamine kinase activity
EXW34_RS22800	COG1523	belongs to the glycosyl hydrolase 13 family
EXW34_RS22810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW34_RS22815	COG1349	DNA-binding transcription factor activity
EXW34_RS22820	COG1187	pseudouridine synthase activity
EXW34_RS22825	COG2244	polysaccharide biosynthetic process
EXW34_RS22830	COG2081	HI0933 family
EXW34_RS22835	COG2814	Major facilitator Superfamily
EXW34_RS22845	COG3832	glyoxalase III activity
EXW34_RS22865	COG1329	Transcriptional regulator
EXW34_RS22890	COG0314	molybdopterin synthase activity
EXW34_RS22895	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW34_RS22900	COG0303	'Molybdopterin
EXW34_RS22905	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW34_RS22910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW34_RS22915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW34_RS22935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW34_RS22945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW34_RS22985	COG0495	leucyl-tRNA aminoacylation
EXW34_RS22990	COG2814	Major facilitator Superfamily
EXW34_RS22995	COG0475	glutathione-regulated potassium exporter activity
EXW34_RS23000	COG0490	domain, Protein
EXW34_RS23005	COG0582	viral genome integration into host DNA
EXW34_RS23015	COG1136	(ABC) transporter
EXW34_RS23035	COG1242	4 iron, 4 sulfur cluster binding
EXW34_RS23040	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW34_RS23045	COG1131	(ABC) transporter
EXW34_RS23055	COG1794	racemase activity, acting on amino acids and derivatives
EXW34_RS23070	COG2267	carboxylic ester hydrolase activity
EXW34_RS23075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW34_RS23080	COG0671	phosphoesterase, PA-phosphatase related
EXW34_RS23085	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS23100	COG0746	molybdenum cofactor guanylyltransferase activity
EXW34_RS23120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW34_RS23125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW34_RS23170	COG5002	protein histidine kinase activity
EXW34_RS23175	COG3852	Histidine kinase
EXW34_RS23180	COG0753	catalase activity
EXW34_RS23185	COG2267	carboxylic ester hydrolase activity
EXW34_RS23195	COG1368	sulfuric ester hydrolase activity
EXW34_RS23205	COG4895	conserved protein (DUF2196)
EXW34_RS23220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW34_RS23225	COG1116	anion transmembrane transporter activity
EXW34_RS23230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW34_RS23255	COG0494	nUDIX hydrolase
EXW34_RS23290	COG1854	S-ribosylhomocysteine lyase activity
EXW34_RS23300	COG0288	reversible hydration of carbon dioxide
EXW34_RS23305	COG1271	oxidase subunit
EXW34_RS23310	COG1294	oxidase, subunit
EXW34_RS23335	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS23360	COG1842	Phage shock protein A
EXW34_RS23385	COG3859	Proton-coupled thiamine transporter YuaJ
EXW34_RS23390	COG5002	protein histidine kinase activity
EXW34_RS23395	COG0745	RESPONSE REGULATOR receiver
EXW34_RS23420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW34_RS23425	COG1597	lipid kinase activity
EXW34_RS23445	COG3344	reverse transcriptase
EXW34_RS23480	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS23495	COG0577	efflux transmembrane transporter activity
EXW34_RS23500	COG1136	(ABC) transporter
EXW34_RS23505	COG2207	Transcriptional regulator
EXW34_RS23505	COG3708	Transcriptional regulator
EXW34_RS23515	COG1131	(ABC) transporter
EXW34_RS23520	COG5658	integral membrane protein
EXW34_RS23525	COG0640	Transcriptional regulator
EXW34_RS23530	COG0745	RESPONSE REGULATOR receiver
EXW34_RS23535	COG2205	protein histidine kinase activity
EXW34_RS23540	COG0577	efflux transmembrane transporter activity
EXW34_RS23545	COG0577	efflux transmembrane transporter activity
EXW34_RS23550	COG1136	(ABC) transporter
EXW34_RS23555	COG0577	efflux transmembrane transporter activity
EXW34_RS23570	COG2188	Transcriptional regulator
EXW34_RS23590	COG3964	amidohydrolase
EXW34_RS23610	COG4948	Mandelate Racemase Muconate Lactonizing
EXW34_RS23615	COG0318	PFAM AMP-dependent synthetase and ligase
EXW34_RS23620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW34_RS23625	COG0596	Alpha beta hydrolase
EXW34_RS23630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW34_RS23635	COG1169	isochorismate synthase
EXW34_RS23640	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW34_RS23645	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW34_RS23650	COG1278	Cold shock
EXW34_RS23665	COG0789	Transcriptional regulator
EXW34_RS23675	COG0058	SHG alpha-glucan phosphorylase activity
EXW34_RS23685	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW34_RS23690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW34_RS23695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW34_RS23845	COG1285	pathogenesis
EXW34_RS23850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW34_RS23860	COG0166	Belongs to the GPI family
EXW34_RS23865	COG2155	Conserved Protein
EXW34_RS23870	COG1098	S1 RNA binding domain
EXW34_RS23875	COG0436	Aminotransferase
EXW34_RS23880	COG1522	sequence-specific DNA binding
EXW34_RS23885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW34_RS23890	COG2267	carboxylic ester hydrolase activity
EXW34_RS23900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW34_RS23920	COG5018	Exonuclease
EXW34_RS23925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW34_RS23945	COG2050	protein possibly involved in aromatic compounds catabolism
EXW34_RS23955	COG1268	BioY protein
EXW34_RS23960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW34_RS23965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW34_RS23975	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW34_RS23980	COG3584	3D domain protein
EXW34_RS23995	COG1252	NADH dehydrogenase
EXW34_RS24000	COG0492	ferredoxin-NADP+ reductase activity
EXW34_RS24005	COG3708	Transcriptional regulator
EXW34_RS24020	COG1683	Conserved Protein
EXW34_RS24030	COG0316	Belongs to the HesB IscA family
EXW34_RS24035	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW34_RS24040	COG4844	belongs to the
EXW34_RS24045	COG1252	NADH dehydrogenase
EXW34_RS24050	COG2274	protein secretion by the type I secretion system
EXW34_RS24055	COG0390	transport system, permease component
EXW34_RS24060	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW34_RS24105	COG4837	Protein of unknown function (DUF1462)
EXW34_RS24110	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW34_RS24120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW34_RS24125	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW34_RS24140	COG1136	(ABC) transporter
EXW34_RS24140	COG0577	efflux transmembrane transporter activity
EXW34_RS24145	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW34_RS24155	COG0647	UMP catabolic process
EXW34_RS24165	COG2445	Protein of unknown function DUF86
EXW34_RS24170	COG1494	fructose-1,6-bisphosphatase
EXW34_RS24190	COG4470	Protein conserved in bacteria
EXW34_RS24200	COG0789	Transcriptional regulator
EXW34_RS24205	COG4377	Putative membrane peptidase family (DUF2324)
EXW34_RS24225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW34_RS24230	COG0739	heme binding
EXW34_RS24240	COG3377	Domain of unknown function (DUF1805)
EXW34_RS24245	COG0737	Belongs to the 5'-nucleotidase family
EXW34_RS24250	COG0719	Fe-S assembly protein
EXW34_RS24255	COG0822	iron-sulfur transferase activity
EXW34_RS24260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW34_RS24265	COG0719	Fe-S assembly protein
EXW34_RS24270	COG0396	ATPase activity
EXW34_RS24275	COG1464	Belongs to the NlpA lipoprotein family
EXW34_RS24280	COG1464	Belongs to the NlpA lipoprotein family
EXW34_RS24285	COG2011	ABC-type metal ion transport system permease component
EXW34_RS24300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW34_RS24305	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW34_RS24310	COG0509	glycine decarboxylation via glycine cleavage system
EXW34_RS24315	COG1393	Belongs to the ArsC family
EXW34_RS24350	COG1309	transcriptional regulator
EXW34_RS24355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW34_RS24360	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS24365	COG0183	Belongs to the thiolase family
EXW34_RS24370	COG1024	Enoyl-CoA hydratase
EXW34_RS24370	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW34_RS24380	COG1686	Belongs to the peptidase S11 family
EXW34_RS24385	COG0506	proline dehydrogenase activity
EXW34_RS24395	COG0011	TIGRFAM Protein of
EXW34_RS24400	COG0840	transmembrane signaling receptor activity
EXW34_RS24415	COG2814	Major facilitator Superfamily
EXW34_RS24420	COG0531	amino acid
EXW34_RS24445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW34_RS24475	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS24485	COG1376	ErfK ybiS ycfS ynhG family protein
EXW34_RS24490	COG0745	RESPONSE REGULATOR receiver
EXW34_RS24495	COG5002	protein histidine kinase activity
EXW34_RS24505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW34_RS24515	COG0840	transmembrane signaling receptor activity
EXW34_RS24520	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW34_RS24525	COG3227	Zinc metalloprotease (Elastase)
EXW34_RS24530	COG1741	Belongs to the pirin family
EXW34_RS24545	COG0586	Pfam SNARE associated Golgi protein
EXW34_RS24550	COG0475	glutathione-regulated potassium exporter activity
EXW34_RS24555	COG0490	domain, Protein
EXW34_RS24560	COG1115	amino acid carrier protein
EXW34_RS24565	COG0783	Belongs to the Dps family
EXW34_RS24575	COG2318	DinB family
EXW34_RS24580	COG1611	Belongs to the LOG family
EXW34_RS24590	COG1528	Iron-storage protein
EXW34_RS24595	COG2311	Membrane
EXW34_RS24600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS24605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS24610	COG1115	amino acid carrier protein
EXW34_RS24615	COG1115	amino acid carrier protein
EXW34_RS24620	COG2910	NAD(P)H-binding
EXW34_RS24630	COG0656	L-ascorbic acid biosynthetic process
EXW34_RS24635	COG2814	Major facilitator Superfamily
EXW34_RS24640	COG1733	regulation of RNA biosynthetic process
EXW34_RS24650	COG1252	NADH dehydrogenase
EXW34_RS24670	COG0840	transmembrane signaling receptor activity
EXW34_RS24670	COG3290	protein histidine kinase activity
EXW34_RS24680	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW34_RS24700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW34_RS24715	COG1522	sequence-specific DNA binding
EXW34_RS24720	COG0288	reversible hydration of carbon dioxide
EXW34_RS24725	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW34_RS24730	COG2233	PERMEase
EXW34_RS24770	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW34_RS24775	COG0557	exoribonuclease II activity
EXW34_RS24780	COG1647	Serine aminopeptidase, S33
EXW34_RS24785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW34_RS24790	COG1346	cytolysis
EXW34_RS24805	COG0148	phosphopyruvate hydratase activity
EXW34_RS24815	COG0149	triose-phosphate isomerase activity
EXW34_RS24820	COG0126	phosphoglycerate kinase activity
EXW34_RS24825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW34_RS24840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW34_RS24875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW34_RS24890	COG2323	membrane
EXW34_RS24900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW34_RS24905	COG1481	regulation of sporulation
EXW34_RS24910	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW34_RS24915	COG1660	Displays ATPase and GTPase activities
EXW34_RS24920	COG1051	belongs to the nudix hydrolase family
EXW34_RS24930	COG0492	ferredoxin-NADP+ reductase activity
EXW34_RS24935	COG0457	Tetratricopeptide repeat
EXW34_RS24940	COG0110	maltose O-acetyltransferase activity
EXW34_RS24945	COG0546	phosphoglycolate phosphatase activity
EXW34_RS24950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW34_RS24955	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW34_RS24960	COG1950	PFAM Membrane protein of
EXW34_RS24965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW34_RS24985	COG0789	Transcriptional regulator
EXW34_RS25020	COG0583	DNA-binding transcription factor activity
EXW34_RS25025	COG0789	Transcriptional regulator
EXW34_RS25030	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW34_RS25035	COG0488	(ABC) transporter
EXW34_RS25045	COG1132	(ABC) transporter
EXW34_RS25050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW34_RS25055	COG0793	Belongs to the peptidase S41A family
EXW34_RS25055	COG3409	Peptidoglycan-binding domain 1 protein
EXW34_RS25060	COG2177	Part of the ABC transporter FtsEX involved in
EXW34_RS25065	COG2884	Cell division ATP-binding protein ftsE
EXW34_RS25100	COG1278	Cold shock
EXW34_RS25105	COG1040	competence protein
EXW34_RS25110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW34_RS25115	COG0791	NLP P60 protein
EXW34_RS25115	COG1388	LysM domain
EXW34_RS25120	COG1733	regulation of RNA biosynthetic process
EXW34_RS25125	COG1307	EDD domain protein, DegV family
EXW34_RS25130	COG1739	Uncharacterized protein family UPF0029
EXW34_RS25135	COG1316	TRANSCRIPTIONal
EXW34_RS25140	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW34_RS25145	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW34_RS25150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW34_RS25160	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW34_RS25160	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW34_RS25180	COG1486	melibiose metabolic process
EXW34_RS25185	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW34_RS25190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW34_RS25210	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW34_RS25220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW34_RS25225	COG1301	dicarboxylic acid transport
EXW34_RS25240	COG1511	domain protein
EXW34_RS25245	COG0583	DNA-binding transcription factor activity
EXW34_RS25250	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW34_RS25260	COG1271	oxidase subunit
EXW34_RS25265	COG1294	oxidase, subunit
EXW34_RS25270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW34_RS25275	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW34_RS25280	COG1620	l-lactate permease
EXW34_RS25290	COG2389	metal-binding protein
EXW34_RS25300	COG1368	sulfuric ester hydrolase activity
EXW34_RS25310	COG0791	NLP P60 protein
EXW34_RS25310	COG1388	LysM domain
EXW34_RS25315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW34_RS25325	COG1215	transferase activity, transferring glycosyl groups
EXW34_RS25330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW34_RS25335	COG1388	LysM domain
EXW34_RS25335	COG3584	3D domain protein
EXW34_RS25345	COG4715	Zinc finger, swim domain protein
EXW34_RS25350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW34_RS25410	COG0577	efflux transmembrane transporter activity
EXW34_RS25415	COG1136	(ABC) transporter
EXW34_RS25440	COG5002	protein histidine kinase activity
EXW34_RS25440	COG3850	Histidine kinase
EXW34_RS25445	COG0745	RESPONSE REGULATOR receiver
EXW34_RS25450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW34_RS25455	COG1316	TRANSCRIPTIONal
EXW34_RS25465	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW34_RS25500	COG1045	serine acetyltransferase
EXW34_RS25505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW34_RS25510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW34_RS25515	COG1086	Polysaccharide biosynthesis protein
EXW34_RS25520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW34_RS25525	COG4464	protein tyrosine phosphatase activity
EXW34_RS25530	COG0489	protein tyrosine kinase activity
EXW34_RS25535	COG3944	biosynthesis protein
EXW34_RS25545	COG1132	(ABC) transporter
EXW34_RS25575	COG0367	asparagine synthase
EXW34_RS25580	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW34_RS25590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW34_RS25600	COG1216	Glycosyl transferase, family 2
EXW34_RS25635	COG1215	transferase activity, transferring glycosyl groups
EXW34_RS25655	COG0463	Glycosyl transferase, family 2
EXW34_RS25655	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW34_RS25665	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS25670	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS25675	COG1086	Polysaccharide biosynthesis protein
EXW34_RS25680	COG0489	protein tyrosine kinase activity
EXW34_RS25685	COG3944	biosynthesis protein
EXW34_RS25695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW34_RS25705	COG1609	Transcriptional regulator
EXW34_RS25715	COG0739	heme binding
EXW34_RS25730	COG3279	Response regulator of the LytR AlgR family
EXW34_RS25735	COG2385	sporulation resulting in formation of a cellular spore
EXW34_RS25750	COG4836	Membrane
EXW34_RS25755	COG1007	ATP synthesis coupled electron transport
EXW34_RS25760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW34_RS25765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW34_RS25770	COG0713	ATP synthesis coupled electron transport
EXW34_RS25775	COG0839	Belongs to the complex I subunit 6 family
EXW34_RS25785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW34_RS25790	COG0649	NAD binding
EXW34_RS25795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW34_RS25800	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW34_RS25805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW34_RS25810	COG3300	MHYT domain
EXW34_RS25810	COG5001	Diguanylate cyclase
EXW34_RS25830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW34_RS25835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW34_RS25850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW34_RS25855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW34_RS25865	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW34_RS25900	COG0698	ribose 5-phosphate isomerase
EXW34_RS25910	COG2190	(PTS) system
EXW34_RS25915	COG2259	Doxx family
EXW34_RS25920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW34_RS25930	COG1971	Probably functions as a manganese efflux pump
EXW34_RS25935	COG0009	L-threonylcarbamoyladenylate synthase
EXW34_RS25950	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW34_RS25955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW34_RS25960	COG1435	thymidine kinase activity
EXW34_RS25970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW34_RS25975	COG1494	fructose-1,6-bisphosphatase
EXW34_RS25995	COG4821	SIS domain
EXW34_RS26000	COG0504	CTP synthase activity
EXW34_RS26005	COG3343	RNA polymerase activity
EXW34_RS26015	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS26020	COG1960	acyl-CoA dehydrogenase activity
EXW34_RS26025	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW34_RS26030	COG0183	Belongs to the thiolase family
EXW34_RS26035	COG2181	nitrate reductase activity
EXW34_RS26035	COG0247	lactate metabolic process
EXW34_RS26040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW34_RS26045	COG4294	response to UV
EXW34_RS26050	COG3300	MHYT domain
EXW34_RS26050	COG5001	Diguanylate cyclase
EXW34_RS26070	COG2197	response regulator
EXW34_RS26075	COG4585	Histidine kinase
EXW34_RS26080	COG0842	Transport permease protein
EXW34_RS26085	COG1131	(ABC) transporter
EXW34_RS26090	COG0024	Methionine aminopeptidase
EXW34_RS26095	COG2234	aminopeptidase activity
EXW34_RS26115	COG4506	Protein conserved in bacteria
EXW34_RS26120	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW34_RS26135	COG0010	Belongs to the arginase family
EXW34_RS26140	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW34_RS26145	COG2814	Major facilitator Superfamily
EXW34_RS26150	COG0789	Transcriptional regulator
EXW34_RS26155	COG0584	glycerophosphoryl diester phosphodiesterase
EXW34_RS26160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW34_RS26170	COG1994	Peptidase M50
EXW34_RS26180	COG1078	dGTPase activity
EXW34_RS26185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW34_RS26190	COG1120	ATPase activity
EXW34_RS26195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS26200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW34_RS26205	COG4844	belongs to the
EXW34_RS26220	COG0280	phosphate acetyltransferase
EXW34_RS26225	COG3253	May function as heme-dependent peroxidase
EXW34_RS26235	COG3773	Cell wall hydrolase
EXW34_RS26245	COG2363	Small membrane protein
EXW34_RS26260	COG2233	PERMEase
EXW34_RS26265	COG0561	phosphatase activity
EXW34_RS26270	COG2814	Major facilitator Superfamily
EXW34_RS26275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW34_RS26280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW34_RS26285	COG1131	(ABC) transporter
EXW34_RS26290	COG2755	lipolytic protein G-D-S-L family
EXW34_RS26295	COG1609	Transcriptional regulator
EXW34_RS26305	COG0460	homoserine dehydrogenase
EXW34_RS26310	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW34_RS26315	COG2873	o-acetylhomoserine
EXW34_RS26330	COG2197	response regulator
EXW34_RS26335	COG4585	Histidine kinase
EXW34_RS26335	COG2203	Gaf domain
EXW34_RS26340	COG0351	phosphomethylpyrimidine kinase
EXW34_RS26345	COG3706	GGDEF domain
EXW34_RS26350	COG2879	small protein
EXW34_RS26355	COG1966	Carbon starvation protein
EXW34_RS26360	COG3279	Response regulator of the LytR AlgR family
EXW34_RS26365	COG0477	Major facilitator Superfamily
EXW34_RS26390	COG0840	transmembrane signaling receptor activity
EXW34_RS26400	COG1607	acyl-coa hydrolase
EXW34_RS26405	COG1216	Glycosyl transferase, family 2
EXW34_RS26415	COG1216	Glycosyl transferase, family 2
EXW34_RS26425	COG0488	(ABC) transporter
EXW34_RS26430	COG1696	Membrane protein involved in D-alanine export
EXW34_RS26440	COG1309	transcriptional regulator
EXW34_RS26445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW34_RS26450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW34_RS26450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW34_RS26455	COG0628	permease
EXW34_RS26460	COG1346	cytolysis
EXW34_RS26465	COG1380	Effector of murein hydrolase LrgA
EXW34_RS26470	COG3279	Response regulator of the LytR AlgR family
EXW34_RS26475	COG3275	phosphorelay sensor kinase activity
EXW34_RS26480	COG2814	Major facilitator Superfamily
EXW34_RS26485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW34_RS26490	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW34_RS26495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW34_RS26545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW34_RS26550	COG1272	protein, Hemolysin III
EXW34_RS26580	COG1164	Oligoendopeptidase f
EXW34_RS26590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW34_RS26600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW34_RS26605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW34_RS26610	COG4853	Protein conserved in bacteria
EXW34_RS26620	COG5002	protein histidine kinase activity
EXW34_RS26625	COG0745	RESPONSE REGULATOR receiver
EXW34_RS26655	COG0305	Participates in initiation and elongation during chromosome replication
EXW34_RS26660	COG0359	binds to the 23S rRNA
EXW34_RS26665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW34_RS26670	COG4241	membrane
EXW34_RS26680	COG0629	single-stranded DNA binding
EXW34_RS26685	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW34_RS26690	COG0012	GTP binding
EXW34_RS26695	COG4481	Protein conserved in bacteria
EXW34_RS26700	COG0668	transmembrane transport
EXW34_RS26710	COG1475	DNA binding
EXW34_RS26715	COG1192	Involved in chromosome partitioning
EXW34_RS26720	COG1475	DNA binding
EXW34_RS26725	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW34_RS26730	COG0445	tRNA wobble uridine modification
EXW34_RS26735	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW34_RS26740	COG1847	R3H domain protein
EXW34_RS26745	COG0706	membrane insertase activity
EXW34_RS26750	COG0594	ribonuclease P activity
EXW34_RS26755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW34_RS26775	COG5002	protein histidine kinase activity
EXW34_RS26815	COG1674	ftsk spoiiie
EXW34_RS26830	COG2002	toxin-antitoxin pair type II binding
EXW34_RS26840	COG3344	reverse transcriptase
EXW34_RS27060	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS27060	COG3409	Peptidoglycan-binding domain 1 protein
EXW34_RS27305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW34_RS27315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW34_RS27345	COG2239	Acts as a magnesium transporter
EXW34_RS27350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW34_RS27365	COG0697	spore germination
EXW34_RS27380	COG0463	Glycosyl transferase, family 2
EXW34_RS27385	COG0463	Glycosyl transferase, family 2
EXW34_RS27390	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW34_RS27395	COG1086	Polysaccharide biosynthesis protein
EXW34_RS27400	COG1088	dTDP-glucose 4,6-dehydratase activity
EXW34_RS27405	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW34_RS27410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EXW34_RS27425	COG2089	acid synthase
EXW34_RS27430	COG4641	Protein conserved in bacteria
EXW34_RS27455	COG0457	Tetratricopeptide repeat
EXW34_RS27495	COG1725	Transcriptional regulator
EXW34_RS27500	COG1131	(ABC) transporter
EXW34_RS27535	COG1696	Membrane protein involved in D-alanine export
EXW34_RS27550	COG0745	RESPONSE REGULATOR receiver
EXW34_RS27570	COG1279	arginine transmembrane transporter activity
EXW34_RS27575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW34_RS27645	COG4974	Belongs to the 'phage' integrase family
EXW34_RS27665	COG0745	RESPONSE REGULATOR receiver
EXW34_RS27690	COG0814	amino acid
EXW34_RS27695	COG1760	l-serine dehydratase
EXW34_RS27700	COG1760	l-serine dehydratase
EXW34_RS27730	COG4977	sequence-specific DNA binding
EXW34_RS27770	COG0456	acetyltransferase
EXW34_RS27785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW34_RS27795	COG0010	Belongs to the arginase family
EXW34_RS27805	COG0662	Cupin 2, conserved barrel domain protein
EXW34_RS27810	COG1999	signal sequence binding
EXW34_RS27825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW34_RS27850	COG2814	Major facilitator Superfamily
EXW34_RS27865	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW34_RS27920	COG1329	Transcriptional regulator
EXW34_RS27975	COG4176	ABC-type proline glycine betaine transport system permease component
EXW34_RS27980	COG0517	IMP dehydrogenase activity
EXW34_RS27980	COG4175	Glycine betaine
EXW34_RS28035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW34_RS28045	COG4974	Belongs to the 'phage' integrase family
EXW34_RS28060	COG0456	acetyltransferase
EXW34_RS28060	COG1846	Transcriptional regulator
EXW34_RS28085	COG2732	(Barnase) inhibitor
EXW34_RS28130	COG0756	dUTP diphosphatase activity
EXW34_RS28150	COG2755	lipolytic protein G-D-S-L family
EXW34_RS28150	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW34_RS28185	COG2720	vancomycin resistance protein
EXW34_RS28235	COG1073	alpha beta
EXW34_RS28245	COG1942	4-Oxalocrotonate Tautomerase
EXW34_RS28250	COG0583	DNA-binding transcription factor activity
EXW34_RS28260	COG2755	lipolytic protein G-D-S-L family
EXW34_RS28260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW34_RS28320	COG2002	toxin-antitoxin pair type II binding
EXW34_RS28340	COG3227	Zinc metalloprotease (Elastase)
EXW34_RS28345	COG2373	Large extracellular alpha-helical protein
EXW34_RS28350	COG3409	Peptidoglycan-binding domain 1 protein
EXW34_RS28350	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW34_RS28440	COG0443	Heat shock 70 kDa protein
EXW34_RS28630	COG2186	Transcriptional regulator
EXW34_RS28680	COG1674	ftsk spoiiie
EXW34_RS28695	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW34_RS28730	COG0535	radical SAM domain protein
EXW34_RS28750	COG0768	penicillin binding
EXW34_RS28760	COG0681	Belongs to the peptidase S26 family
EXW34_RS28805	COG0582	viral genome integration into host DNA
EXW34_RS28845	COG2732	(Barnase) inhibitor
EXW34_RS28865	COG3615	Tellurite resistance protein tehB
EXW34_RS28865	COG0500	methyltransferase
EXW34_RS28890	COG2732	(Barnase) inhibitor
EXW34_RS28910	COG1476	TRANSCRIPTIONal
EXW34_RS28955	COG2801	Transposase and inactivated derivatives
EXW34_RS29030	COG2508	Transcriptional regulator
EXW34_RS29030	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW34_RS29035	COG0686	Belongs to the AlaDH PNT family
EXW34_RS29130	COG0582	viral genome integration into host DNA
EXW34_RS29145	COG2378	regulation of single-species biofilm formation
EXW34_RS29150	COG2318	DinB family
EXW34_RS29255	COG0531	amino acid
EXW34_RS29270	COG0531	amino acid
EXW34_RS29280	COG2070	2-Nitropropane dioxygenase
EXW34_RS29315	COG0302	gtp cyclohydrolase
EXW34_RS29325	COG0720	synthase
EXW34_RS29345	COG4555	ABC transporter
EXW34_RS29355	COG2226	methyltransferase
EXW34_RS29390	COG0697	spore germination
EXW34_RS29395	COG0814	amino acid
EXW34_RS29410	COG0577	efflux transmembrane transporter activity
EXW34_RS29415	COG1136	(ABC) transporter
EXW34_RS29475	COG1454	alcohol dehydrogenase
EXW34_RS29475	COG1012	belongs to the aldehyde dehydrogenase family
EXW34_RS29500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW34_RS29510	COG2707	UPF0756 membrane protein
EXW34_RS29515	COG0596	Alpha beta hydrolase
EXW34_RS29520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW34_RS29570	COG1278	Cold shock
EXW34_RS29660	COG3883	PFAM NLP P60 protein
EXW34_RS29660	COG0791	NLP P60 protein
EXW34_RS29715	COG3547	Transposase (IS116 IS110 IS902 family)
EXW34_RS29785	COG1192	Involved in chromosome partitioning
EXW34_RS29885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW34_RS29885	COG0551	DNA topoisomerase type I activity
EXW34_RS29915	COG0024	Methionine aminopeptidase
EXW34_RS29930	COG1388	LysM domain
EXW34_RS30005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW34_RS30010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW34_RS30015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW34_RS30020	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS30040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW34_RS30045	COG0438	transferase activity, transferring glycosyl groups
EXW34_RS30050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW34_RS30140	COG3773	Cell wall hydrolase
EXW34_RS30175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW34_RS30190	COG4641	Protein conserved in bacteria
EXW34_RS30190	COG1388	LysM domain
EXW34_RS30195	COG1388	LysM domain
EXW34_RS30195	COG4641	Protein conserved in bacteria
EXW34_RS30200	COG4641	Protein conserved in bacteria
EXW34_RS30200	COG1388	LysM domain
EXW34_RS30210	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW34_RS30305	COG0463	Glycosyl transferase, family 2
EXW34_RS30305	COG0457	Tetratricopeptide repeat
EXW34_RS30350	COG4166	transmembrane transport
EXW34_RS30390	COG0741	lytic transglycosylase activity
EXW34_RS30390	COG0791	NLP P60 protein
EXW34_RS30470	COG0582	viral genome integration into host DNA
EXW34_RS30485	COG3290	protein histidine kinase activity
EXW34_RS30485	COG0840	transmembrane signaling receptor activity
EXW34_RS30555	COG0662	Cupin 2, conserved barrel domain protein
EXW34_RS30605	COG1278	Cold shock
EXW34_RS30650	COG1476	TRANSCRIPTIONal
EXW34_RS31150	COG2755	lipolytic protein G-D-S-L family
EXW34_RS31150	COG0657	acetylesterase activity