locus-tag	class	description
EXW57_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EXW57_RS00010	COG0592	DNA-directed DNA polymerase activity
EXW57_RS00015	COG2501	S4 domain
EXW57_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EXW57_RS00025	COG0187	DNA topoisomerase II activity
EXW57_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW57_RS00065	COG0516	GMP reductase activity
EXW57_RS00065	COG0517	IMP dehydrogenase activity
EXW57_RS00070	COG1686	Belongs to the peptidase S11 family
EXW57_RS00075	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EXW57_RS00080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EXW57_RS00100	COG1428	Deoxynucleoside kinase
EXW57_RS00105	COG1428	Deoxynucleoside kinase
EXW57_RS00110	COG1335	isochorismatase
EXW57_RS00115	COG0590	tRNA wobble adenosine to inosine editing
EXW57_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EXW57_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EXW57_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EXW57_RS00180	COG1982	Orn Lys Arg decarboxylase major
EXW57_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EXW57_RS00190	COG0470	DNA polymerase III
EXW57_RS00195	COG1774	PSP1 C-terminal conserved region
EXW57_RS00200	COG4467	Involved in initiation control of chromosome replication
EXW57_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EXW57_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EXW57_RS00220	COG2002	toxin-antitoxin pair type II binding
EXW57_RS00230	COG0084	hydrolase, TatD family'
EXW57_RS00240	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EXW57_RS00250	COG4466	Protein conserved in bacteria
EXW57_RS00260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EXW57_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW57_RS00270	COG0251	oxidation-reduction process
EXW57_RS00275	COG2088	sporulation resulting in formation of a cellular spore
EXW57_RS00280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EXW57_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EXW57_RS00305	COG2002	toxin-antitoxin pair type II binding
EXW57_RS00310	COG2244	polysaccharide biosynthetic process
EXW57_RS00315	COG3956	TIGRFAM MazG family protein
EXW57_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EXW57_RS00340	COG1098	S1 RNA binding domain
EXW57_RS00355	COG2208	phosphoserine phosphatase activity
EXW57_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW57_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EXW57_RS00375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EXW57_RS00380	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EXW57_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EXW57_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW57_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EXW57_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EXW57_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EXW57_RS00420	COG1396	sequence-specific DNA binding
EXW57_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW57_RS00430	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EXW57_RS00515	COG3880	PFAM UvrB UvrC protein
EXW57_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
EXW57_RS00525	COG0542	response to heat
EXW57_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EXW57_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EXW57_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
EXW57_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EXW57_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EXW57_RS00560	COG1045	serine acetyltransferase
EXW57_RS00565	COG0215	cysteine-tRNA ligase activity
EXW57_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW57_RS00580	COG3688	RNA-binding protein containing a PIN domain
EXW57_RS00590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW57_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW57_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
EXW57_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EXW57_RS00610	COG0081	regulation of translation
EXW57_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EXW57_RS00620	COG0222	ribosome binding
EXW57_RS00625	COG2813	Specifically methylates the guanine in position
EXW57_RS00630	COG0085	RNA polymerase activity
EXW57_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EXW57_RS00640	COG1358	cellular component organization or biogenesis
EXW57_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EXW57_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EXW57_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EXW57_RS00665	COG0051	transcription antitermination factor activity, RNA binding
EXW57_RS00670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EXW57_RS00675	COG0088	Forms part of the polypeptide exit tunnel
EXW57_RS00680	COG0089	rRNA binding
EXW57_RS00685	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EXW57_RS00690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EXW57_RS00695	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EXW57_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
EXW57_RS00715	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EXW57_RS00725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EXW57_RS00730	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EXW57_RS00740	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EXW57_RS00750	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EXW57_RS00760	COG1841	ribosomal large subunit assembly
EXW57_RS00765	COG0200	Binds to the 23S rRNA
EXW57_RS00770	COG0201	protein transport
EXW57_RS00775	COG0563	adenylate kinase activity
EXW57_RS00780	COG0024	Methionine aminopeptidase
EXW57_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EXW57_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EXW57_RS00800	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EXW57_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EXW57_RS00835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EXW57_RS00840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EXW57_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS00855	COG0489	protein tyrosine kinase activity
EXW57_RS00865	COG2194	sulfuric ester hydrolase activity
EXW57_RS00870	COG0726	polysaccharide deacetylase
EXW57_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EXW57_RS00955	COG4856	YbbR-like protein
EXW57_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW57_RS00985	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS00990	COG2011	ABC-type metal ion transport system permease component
EXW57_RS01000	COG1464	Belongs to the NlpA lipoprotein family
EXW57_RS01005	COG0604	alcohol dehydrogenase
EXW57_RS01015	COG0277	FAD linked oxidase domain protein
EXW57_RS01020	COG2271	Major facilitator Superfamily
EXW57_RS01030	COG2814	Major facilitator Superfamily
EXW57_RS01045	COG0601	transmembrane transport
EXW57_RS01050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_RS01055	COG0444	Belongs to the ABC transporter superfamily
EXW57_RS01060	COG4608	Belongs to the ABC transporter superfamily
EXW57_RS01065	COG4166	transmembrane transport
EXW57_RS01075	COG2207	Transcriptional regulator
EXW57_RS01090	COG4166	transmembrane transport
EXW57_RS01095	COG4166	transmembrane transport
EXW57_RS01100	COG0656	L-ascorbic acid biosynthetic process
EXW57_RS01120	COG4149	molybdate abc transporter
EXW57_RS01125	COG0725	ABC transporter, periplasmic molybdate-binding protein
EXW57_RS01130	COG1910	domain protein
EXW57_RS01145	COG0697	spore germination
EXW57_RS01160	COG0204	Acyl-transferase
EXW57_RS01170	COG1609	Transcriptional regulator
EXW57_RS01180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS01195	COG5298	Protein conserved in bacteria
EXW57_RS01215	COG0488	(ABC) transporter
EXW57_RS01220	COG4585	Histidine kinase
EXW57_RS01225	COG2197	response regulator
EXW57_RS01230	COG1131	(ABC) transporter
EXW57_RS01235	COG0842	Transport permease protein
EXW57_RS01235	COG1511	domain protein
EXW57_RS01240	COG0842	Transport permease protein
EXW57_RS01250	COG0747	negative chemotaxis
EXW57_RS01260	COG0601	transmembrane transport
EXW57_RS01265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_RS01270	COG0444	Belongs to the ABC transporter superfamily
EXW57_RS01275	COG4608	Belongs to the ABC transporter superfamily
EXW57_RS01280	COG0561	phosphatase activity
EXW57_RS01310	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EXW57_RS01315	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW57_RS01325	COG0531	amino acid
EXW57_RS01330	COG2814	Major facilitator Superfamily
EXW57_RS01340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EXW57_RS01350	COG4294	response to UV
EXW57_RS01355	COG0705	Rhomboid family
EXW57_RS01360	COG0736	holo-[acyl-carrier-protein] synthase activity
EXW57_RS01365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EXW57_RS01375	COG0864	Transcriptional regulator
EXW57_RS01380	COG2337	Toxic component of a toxin-antitoxin (TA) module
EXW57_RS01385	COG2183	response to ionizing radiation
EXW57_RS01485	COG0802	atpase or kinase
EXW57_RS01490	COG1214	PFAM Peptidase M22, glycoprotease
EXW57_RS01495	COG0456	acetyltransferase
EXW57_RS01505	COG0488	(ABC) transporter
EXW57_RS01510	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EXW57_RS01520	COG1266	CAAX protease self-immunity
EXW57_RS01525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EXW57_RS01530	COG0459	protein refolding
EXW57_RS01535	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EXW57_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
EXW57_RS01540	COG2252	PERMEase
EXW57_RS01550	COG5002	protein histidine kinase activity
EXW57_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW57_RS01630	COG2205	protein histidine kinase activity
EXW57_RS01635	COG0745	RESPONSE REGULATOR receiver
EXW57_RS01655	COG0697	spore germination
EXW57_RS01680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EXW57_RS01685	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EXW57_RS01690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EXW57_RS01695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EXW57_RS01700	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW57_RS01705	COG0047	phosphoribosylformylglycinamidine synthase activity
EXW57_RS01710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EXW57_RS01715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EXW57_RS01720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EXW57_RS01725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EXW57_RS01730	COG0138	bifunctional purine biosynthesis protein purh
EXW57_RS01735	COG0151	Belongs to the GarS family
EXW57_RS01755	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EXW57_RS01760	COG0210	DNA helicase
EXW57_RS01765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EXW57_RS01770	COG4851	CamS sex pheromone cAM373 precursor
EXW57_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS01785	COG1335	isochorismatase
EXW57_RS01795	COG2011	ABC-type metal ion transport system permease component
EXW57_RS01800	COG1464	Belongs to the NlpA lipoprotein family
EXW57_RS01815	COG0003	Pfam Anion-transporting ATPase
EXW57_RS01820	COG1846	Transcriptional regulator
EXW57_RS01825	COG4682	membrane
EXW57_RS01835	COG0154	amidase activity
EXW57_RS01840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EXW57_RS01845	COG1597	lipid kinase activity
EXW57_RS01850	COG0546	phosphoglycolate phosphatase activity
EXW57_RS01855	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS01870	COG2076	Multidrug Resistance protein
EXW57_RS01875	COG2309	aminopeptidase activity
EXW57_RS01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS01900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EXW57_RS01905	COG5002	protein histidine kinase activity
EXW57_RS01910	COG4807	Protein conserved in bacteria
EXW57_RS01935	COG1757	Na H antiporter
EXW57_RS01940	COG1473	amidohydrolase
EXW57_RS01955	COG0450	alkyl hydroperoxide reductase
EXW57_RS01965	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW57_RS01975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS01980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS01985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS01990	COG0492	ferredoxin-NADP+ reductase activity
EXW57_RS02000	COG0166	Belongs to the GPI family
EXW57_RS02025	COG5002	protein histidine kinase activity
EXW57_RS02045	COG3541	Predicted nucleotidyltransferase
EXW57_RS02050	COG2814	Major facilitator Superfamily
EXW57_RS02055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_RS02055	COG0723	plastoquinol--plastocyanin reductase activity
EXW57_RS02065	COG0765	amino acid transport
EXW57_RS02070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_RS02080	COG0840	transmembrane signaling receptor activity
EXW57_RS02085	COG0277	FAD linked oxidase domain protein
EXW57_RS02090	COG0366	Alpha amylase catalytic
EXW57_RS02095	COG1263	PTS System
EXW57_RS02095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS02095	COG2190	(PTS) system
EXW57_RS02115	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EXW57_RS02120	COG0352	thiamine-phosphate diphosphorylase activity
EXW57_RS02125	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EXW57_RS02140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_RS02145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_RS02150	COG1116	anion transmembrane transporter activity
EXW57_RS02155	COG0488	(ABC) transporter
EXW57_RS02200	COG2270	Major facilitator Superfamily
EXW57_RS02230	COG2310	stress, protein
EXW57_RS02235	COG2310	stress, protein
EXW57_RS02240	COG2310	stress, protein
EXW57_RS02245	COG0861	Integral membrane protein TerC family
EXW57_RS02255	COG3853	Toxic anion resistance protein (TelA)
EXW57_RS02265	COG4840	Belongs to the UPF0435 family
EXW57_RS02270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EXW57_RS02280	COG1295	ribonuclease BN
EXW57_RS02285	COG2217	Heavy metal translocating P-type atpase
EXW57_RS02290	COG0697	spore germination
EXW57_RS02310	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS02325	COG3871	stress protein (general stress protein 26)
EXW57_RS02330	COG0387	Pfam Sodium calcium exchanger
EXW57_RS02340	COG0535	radical SAM domain protein
EXW57_RS02360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW57_RS02380	COG3829	transcription factor binding
EXW57_RS02390	COG0833	amino acid
EXW57_RS02395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_RS02415	COG2066	Belongs to the glutaminase family
EXW57_RS02420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS02420	COG1263	PTS System
EXW57_RS02425	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS02440	COG1216	Glycosyl transferase, family 2
EXW57_RS02450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW57_RS02450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW57_RS02455	COG0463	Glycosyl transferase, family 2
EXW57_RS02470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EXW57_RS02475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EXW57_RS02490	COG1228	amidohydrolase
EXW57_RS02495	COG1090	epimerase
EXW57_RS02500	COG2137	regulation of response to DNA damage stimulus
EXW57_RS02525	COG1988	membrane-bound metal-dependent
EXW57_RS02530	COG1194	a g-specific adenine glycosylase
EXW57_RS02550	COG3557	Belongs to the UPF0374 family
EXW57_RS02555	COG1132	(ABC) transporter
EXW57_RS02560	COG4129	membrane
EXW57_RS02565	COG0070	glutamate synthase
EXW57_RS02565	COG0069	glutamate synthase activity
EXW57_RS02565	COG0067	glutamate synthase
EXW57_RS02570	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW57_RS02575	COG4555	ABC transporter
EXW57_RS02595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EXW57_RS02600	COG0735	belongs to the Fur family
EXW57_RS02720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EXW57_RS02725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EXW57_RS02745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EXW57_RS02755	COG2766	serine protein kinase
EXW57_RS02760	COG2718	Belongs to the UPF0229 family
EXW57_RS02775	COG1585	Membrane protein implicated in regulation of membrane protease activity
EXW57_RS02780	COG2268	Band 7 protein
EXW57_RS02790	COG3290	protein histidine kinase activity
EXW57_RS02795	COG4565	transcriptional regulatory protein
EXW57_RS02800	COG2851	Citrate transporter
EXW57_RS02825	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW57_RS02830	COG3842	ATPase activity
EXW57_RS02835	COG1175	transmembrane transport
EXW57_RS02840	COG0395	ABC-type sugar transport system, permease component
EXW57_RS02850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW57_RS02855	COG0745	RESPONSE REGULATOR receiver
EXW57_RS02860	COG5002	protein histidine kinase activity
EXW57_RS02870	COG4990	cell redox homeostasis
EXW57_RS02880	COG3290	protein histidine kinase activity
EXW57_RS02885	COG4565	transcriptional regulatory protein
EXW57_RS02890	COG3493	citrate carrier protein
EXW57_RS02895	COG0281	malic enzyme
EXW57_RS02905	COG0697	spore germination
EXW57_RS02910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS02920	COG5002	protein histidine kinase activity
EXW57_RS02925	COG0745	RESPONSE REGULATOR receiver
EXW57_RS02930	COG0456	acetyltransferase
EXW57_RS02935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW57_RS02940	COG3383	formate dehydrogenase (NAD+) activity
EXW57_RS02945	COG2427	Protein of unknown function (DUF1641)
EXW57_RS02960	COG0531	amino acid
EXW57_RS02970	COG0640	Transcriptional regulator
EXW57_RS02975	COG2217	Heavy metal translocating P-type atpase
EXW57_RS02980	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EXW57_RS02995	COG3227	Zinc metalloprotease (Elastase)
EXW57_RS03015	COG2720	vancomycin resistance protein
EXW57_RS03020	COG1316	TRANSCRIPTIONal
EXW57_RS03025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS03030	COG0346	lactoylglutathione lyase activity
EXW57_RS03035	COG1253	flavin adenine dinucleotide binding
EXW57_RS03040	COG1027	Aspartate ammonia-lyase
EXW57_RS03045	COG1620	l-lactate permease
EXW57_RS03050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS03065	COG3104	oligopeptide transport
EXW57_RS03070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS03075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS03080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS03095	COG0156	8-amino-7-oxononanoate synthase activity
EXW57_RS03100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EXW57_RS03110	COG4548	von Willebrand factor, type A
EXW57_RS03115	COG0714	Associated with various cellular activities
EXW57_RS03135	COG0531	amino acid
EXW57_RS03140	COG2188	Transcriptional regulator
EXW57_RS03145	COG1263	PTS System
EXW57_RS03145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS03150	COG0366	Alpha amylase catalytic
EXW57_RS03165	COG0697	spore germination
EXW57_RS03170	COG4585	Histidine kinase
EXW57_RS03175	COG2197	response regulator
EXW57_RS03180	COG1404	Belongs to the peptidase S8 family
EXW57_RS03195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW57_RS03200	COG1115	amino acid carrier protein
EXW57_RS03205	COG1126	abc transporter atp-binding protein
EXW57_RS03210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_RS03215	COG0765	amino acid transport
EXW57_RS03220	COG0765	amino acid transport
EXW57_RS03225	COG0833	amino acid
EXW57_RS03235	COG2378	regulation of single-species biofilm formation
EXW57_RS03240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EXW57_RS03245	COG5002	protein histidine kinase activity
EXW57_RS03260	COG0659	secondary active sulfate transmembrane transporter activity
EXW57_RS03275	COG2271	Major facilitator Superfamily
EXW57_RS03280	COG1846	Transcriptional regulator
EXW57_RS03285	COG0477	Major facilitator Superfamily
EXW57_RS03290	COG1609	Transcriptional regulator
EXW57_RS03295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW57_RS03300	COG1869	D-ribose catabolic process
EXW57_RS03310	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_RS03315	COG1879	ABC-type sugar transport system periplasmic component
EXW57_RS03345	COG1063	alcohol dehydrogenase
EXW57_RS03360	COG3568	Endonuclease Exonuclease Phosphatase
EXW57_RS03390	COG0840	transmembrane signaling receptor activity
EXW57_RS03395	COG3584	3D domain protein
EXW57_RS03395	COG1388	LysM domain
EXW57_RS03400	COG1476	TRANSCRIPTIONal
EXW57_RS03420	COG3104	oligopeptide transport
EXW57_RS03425	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS03440	COG1113	amino acid transport
EXW57_RS03445	COG2252	PERMEase
EXW57_RS03460	COG2153	protein acetylation
EXW57_RS03470	COG0475	glutathione-regulated potassium exporter activity
EXW57_RS03470	COG0569	domain protein
EXW57_RS03480	COG1845	cytochrome c oxidase, subunit III
EXW57_RS03485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EXW57_RS03495	COG0833	amino acid
EXW57_RS03500	COG4990	cell redox homeostasis
EXW57_RS03515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_RS03520	COG0697	spore germination
EXW57_RS03525	COG0531	amino acid
EXW57_RS03535	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW57_RS03540	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EXW57_RS03550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW57_RS03555	COG0573	inorganic phosphate transmembrane transporter activity
EXW57_RS03560	COG0581	inorganic phosphate transmembrane transporter activity
EXW57_RS03570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW57_RS03690	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EXW57_RS03705	COG4991	sh3 domain protein
EXW57_RS03705	COG3103	Sh3 type 3 domain protein
EXW57_RS03705	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS03710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW57_RS03715	COG1116	anion transmembrane transporter activity
EXW57_RS03720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_RS03725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_RS03730	COG0352	thiamine-phosphate diphosphorylase activity
EXW57_RS03735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_RS03740	COG2104	thiamine diphosphate biosynthetic process
EXW57_RS03745	COG2022	thiamine diphosphate biosynthetic process
EXW57_RS03750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_RS03755	COG0351	phosphomethylpyrimidine kinase
EXW57_RS03780	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EXW57_RS03785	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EXW57_RS03790	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EXW57_RS03795	COG2205	protein histidine kinase activity
EXW57_RS03800	COG2814	Major facilitator Superfamily
EXW57_RS03805	COG1846	Transcriptional regulator
EXW57_RS03825	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_RS03830	COG1129	ABC transporter
EXW57_RS03835	COG1879	ABC-type sugar transport system periplasmic component
EXW57_RS03840	COG2252	PERMEase
EXW57_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS03860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EXW57_RS03865	COG1621	beta-fructofuranosidase activity
EXW57_RS03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS03870	COG1263	PTS System
EXW57_RS03875	COG1609	Transcriptional regulator
EXW57_RS03925	COG0778	Nitroreductase
EXW57_RS03930	COG2719	SpoVR family
EXW57_RS03955	COG1937	Protein conserved in bacteria
EXW57_RS03960	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_RS03960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS03965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS03965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS03970	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_RS03975	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_RS03975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS03980	COG2210	Belongs to the sulfur carrier protein TusA family
EXW57_RS03985	COG0730	response to heat
EXW57_RS03995	COG1316	TRANSCRIPTIONal
EXW57_RS04000	COG0604	alcohol dehydrogenase
EXW57_RS04005	COG1283	sodium-dependent phosphate transmembrane transporter activity
EXW57_RS04010	COG0604	alcohol dehydrogenase
EXW57_RS04015	COG2814	Major facilitator Superfamily
EXW57_RS04025	COG3711	transcriptional antiterminator
EXW57_RS04025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_RS04030	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_RS04035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_RS04060	COG1388	LysM domain
EXW57_RS04060	COG3584	3D domain protein
EXW57_RS04065	COG0577	efflux transmembrane transporter activity
EXW57_RS04070	COG1136	(ABC) transporter
EXW57_RS04080	COG5522	Integral membrane protein (intg_mem_TP0381)
EXW57_RS04095	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS04100	COG3546	catalase activity
EXW57_RS04130	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS04160	COG0531	amino acid
EXW57_RS04165	COG0475	glutathione-regulated potassium exporter activity
EXW57_RS04175	COG1737	Transcriptional regulator
EXW57_RS04180	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EXW57_RS04185	COG1263	PTS System
EXW57_RS04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS04195	COG2259	Doxx family
EXW57_RS04215	COG0697	spore germination
EXW57_RS04220	COG1522	sequence-specific DNA binding
EXW57_RS04230	COG0300	oxidoreductase activity
EXW57_RS04245	COG2076	Multidrug Resistance protein
EXW57_RS04250	COG1309	transcriptional regulator
EXW57_RS04255	COG2814	Major facilitator Superfamily
EXW57_RS04260	COG1733	regulation of RNA biosynthetic process
EXW57_RS04275	COG4533	DNA binding
EXW57_RS04280	COG2211	Major facilitator Superfamily
EXW57_RS04290	COG0693	protein deglycase activity
EXW57_RS04300	COG0531	amino acid
EXW57_RS04305	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS04310	COG1132	(ABC) transporter
EXW57_RS04315	COG1132	(ABC) transporter
EXW57_RS04320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_RS04325	COG0765	amino acid transport
EXW57_RS04330	COG1126	abc transporter atp-binding protein
EXW57_RS04345	COG0189	ligase activity
EXW57_RS04355	COG4399	Belongs to the UPF0754 family
EXW57_RS04360	COG3679	Belongs to the UPF0342 family
EXW57_RS04375	COG0028	Belongs to the TPP enzyme family
EXW57_RS04380	COG3527	Alpha-acetolactate decarboxylase
EXW57_RS04385	COG0463	Glycosyl transferase, family 2
EXW57_RS04390	COG1216	Glycosyl transferase, family 2
EXW57_RS04395	COG2094	Belongs to the DNA glycosylase MPG family
EXW57_RS04400	COG0561	phosphatase activity
EXW57_RS04410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW57_RS04415	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS04425	COG0659	secondary active sulfate transmembrane transporter activity
EXW57_RS04440	COG0653	protein targeting
EXW57_RS04445	COG2244	polysaccharide biosynthetic process
EXW57_RS04455	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS04475	COG1696	Membrane protein involved in D-alanine export
EXW57_RS04490	COG1024	Enoyl-CoA hydratase
EXW57_RS04505	COG1363	Peptidase, m42
EXW57_RS04520	COG2318	DinB family
EXW57_RS04540	COG0579	oxidoreductase
EXW57_RS04575	COG0601	transmembrane transport
EXW57_RS04580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_RS04585	COG0444	Belongs to the ABC transporter superfamily
EXW57_RS04590	COG4608	Belongs to the ABC transporter superfamily
EXW57_RS04685	COG0582	viral genome integration into host DNA
EXW57_RS04775	COG0477	Major facilitator Superfamily
EXW57_RS04780	COG3290	protein histidine kinase activity
EXW57_RS04785	COG4565	transcriptional regulatory protein
EXW57_RS04790	COG3181	Tripartite tricarboxylate transporter family receptor
EXW57_RS04835	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EXW57_RS04860	COG0789	Transcriptional regulator
EXW57_RS04860	COG4978	Transcriptional regulator
EXW57_RS04875	COG0305	Participates in initiation and elongation during chromosome replication
EXW57_RS04905	COG0477	Major facilitator Superfamily
EXW57_RS04940	COG3711	transcriptional antiterminator
EXW57_RS04945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS04945	COG1263	PTS System
EXW57_RS04945	COG2190	(PTS) system
EXW57_RS04950	COG2723	6-phospho-beta-galactosidase activity
EXW57_RS04955	COG0456	acetyltransferase
EXW57_RS04965	COG1183	phosphatidylcholine synthase activity
EXW57_RS05020	COG2814	Major facilitator Superfamily
EXW57_RS05025	COG0640	Transcriptional regulator
EXW57_RS05045	COG2376	Dihydroxyacetone kinase
EXW57_RS05055	COG2376	Dihydroxyacetone kinase
EXW57_RS05070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW57_RS05085	COG1335	isochorismatase
EXW57_RS05110	COG0076	glutamate decarboxylase activity
EXW57_RS05130	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS05130	COG4085	toxin activity
EXW57_RS05130	COG1525	nuclease
EXW57_RS05140	COG0582	viral genome integration into host DNA
EXW57_RS05150	COG2378	regulation of single-species biofilm formation
EXW57_RS05155	COG2318	DinB family
EXW57_RS05160	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EXW57_RS05160	COG4932	domain protein
EXW57_RS05160	COG3266	domain, Protein
EXW57_RS05170	COG0825	malonyl-CoA metabolic process
EXW57_RS05190	COG3237	CsbD-like
EXW57_RS05210	COG2172	sigma factor antagonist activity
EXW57_RS05215	COG1191	sigma factor activity
EXW57_RS05225	COG2208	phosphoserine phosphatase activity
EXW57_RS05230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW57_RS05235	COG2205	protein histidine kinase activity
EXW57_RS05235	COG0784	Response regulator, receiver
EXW57_RS05235	COG5002	protein histidine kinase activity
EXW57_RS05280	COG2807	transmembrane transport
EXW57_RS05285	COG2186	Transcriptional regulator
EXW57_RS05290	COG4585	Histidine kinase
EXW57_RS05295	COG2197	response regulator
EXW57_RS05325	COG0420	3'-5' exonuclease activity
EXW57_RS05330	COG4717	serine-type aminopeptidase activity
EXW57_RS05335	COG3481	metal-dependent phosphohydrolase, HD sub domain
EXW57_RS05345	COG0346	lactoylglutathione lyase activity
EXW57_RS05360	COG2267	carboxylic ester hydrolase activity
EXW57_RS05375	COG3620	sequence-specific DNA binding
EXW57_RS05380	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EXW57_RS05385	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EXW57_RS05390	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EXW57_RS05395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EXW57_RS05400	COG1595	DNA-templated transcription, initiation
EXW57_RS05415	COG3973	AAA domain
EXW57_RS05420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_RS05435	COG1846	Transcriptional regulator
EXW57_RS05445	COG0537	adenosine 5'-monophosphoramidase activity
EXW57_RS05450	COG1131	(ABC) transporter
EXW57_RS05455	COG4473	ABC transporter
EXW57_RS05465	COG0247	lactate metabolic process
EXW57_RS05470	COG1139	Iron-sulfur cluster binding protein
EXW57_RS05475	COG1556	Lactate utilization protein
EXW57_RS05495	COG3402	PFAM membrane-flanked domain
EXW57_RS05500	COG3428	Bacterial PH domain
EXW57_RS05530	COG3402	PFAM membrane-flanked domain
EXW57_RS05535	COG3428	Bacterial PH domain
EXW57_RS05540	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_RS05545	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS05550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EXW57_RS05555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EXW57_RS05560	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW57_RS05585	COG1309	transcriptional regulator
EXW57_RS05590	COG1511	domain protein
EXW57_RS05625	COG2378	regulation of single-species biofilm formation
EXW57_RS05630	COG1609	Transcriptional regulator
EXW57_RS05640	COG1234	tRNA 3'-trailer cleavage
EXW57_RS05645	COG0095	Lipoate-protein ligase
EXW57_RS05655	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS05670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EXW57_RS05675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EXW57_RS05680	COG4208	sulfate ABC transporter
EXW57_RS05695	COG1408	metallophosphoesterase
EXW57_RS05700	COG1078	dGTPase activity
EXW57_RS05715	COG1595	DNA-templated transcription, initiation
EXW57_RS05720	COG3708	Transcriptional regulator
EXW57_RS05720	COG2207	Transcriptional regulator
EXW57_RS05725	COG2205	protein histidine kinase activity
EXW57_RS05730	COG0745	RESPONSE REGULATOR receiver
EXW57_RS05745	COG0501	Belongs to the peptidase M48B family
EXW57_RS05750	COG0697	spore germination
EXW57_RS05775	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EXW57_RS05780	COG2224	Isocitrate lyase
EXW57_RS05790	COG1278	Cold shock
EXW57_RS05800	COG4903	ComK protein
EXW57_RS05805	COG0398	Pfam SNARE associated Golgi protein
EXW57_RS05815	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EXW57_RS05820	COG1074	ATP-dependent DNA helicase activity
EXW57_RS05870	COG0179	Fumarylacetoacetate (FAA) hydrolase
EXW57_RS05895	COG0367	asparagine synthase
EXW57_RS05905	COG0753	catalase activity
EXW57_RS05910	COG0004	ammonium transporteR
EXW57_RS05920	COG1666	GTP binding
EXW57_RS05925	COG2996	Protein conserved in bacteria
EXW57_RS05930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_RS05940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS05955	COG0561	phosphatase activity
EXW57_RS05975	COG2267	carboxylic ester hydrolase activity
EXW57_RS05990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_RS05995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EXW57_RS06000	COG5504	Zn-dependent protease
EXW57_RS06010	COG0180	Tryptophanyl-tRNA synthetase
EXW57_RS06020	COG4166	transmembrane transport
EXW57_RS06025	COG0601	transmembrane transport
EXW57_RS06030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EXW57_RS06035	COG0444	Belongs to the ABC transporter superfamily
EXW57_RS06040	COG4608	Belongs to the ABC transporter superfamily
EXW57_RS06045	COG0534	Mate efflux family protein
EXW57_RS06050	COG4166	transmembrane transport
EXW57_RS06065	COG0861	Integral membrane protein TerC family
EXW57_RS06070	COG4862	establishment of competence for transformation
EXW57_RS06075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS06085	COG1164	Oligoendopeptidase f
EXW57_RS06100	COG2346	COG2346, Truncated hemoglobins
EXW57_RS06105	COG4116	CYTH
EXW57_RS06115	COG2357	RelA SpoT domain protein
EXW57_RS06125	COG0564	pseudouridine synthase activity
EXW57_RS06135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EXW57_RS06140	COG0772	Belongs to the SEDS family
EXW57_RS06145	COG1216	Glycosyl transferase, family 2
EXW57_RS06165	COG0457	Tetratricopeptide repeat
EXW57_RS06165	COG0463	Glycosyl transferase, family 2
EXW57_RS06185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EXW57_RS06200	COG1091	dTDP-4-dehydrorhamnose reductase activity
EXW57_RS06245	COG2153	protein acetylation
EXW57_RS06250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EXW57_RS06255	COG2382	esterase
EXW57_RS06280	COG5492	domain, Protein
EXW57_RS06285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_RS06295	COG0512	Glutamine amidotransferase of anthranilate synthase
EXW57_RS06295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW57_RS06300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EXW57_RS06305	COG0134	indole-3-glycerol-phosphate synthase activity
EXW57_RS06310	COG0135	phosphoribosylanthranilate isomerase activity
EXW57_RS06315	COG0133	tryptophan synthase activity
EXW57_RS06320	COG0159	tryptophan synthase activity
EXW57_RS06330	COG1620	l-lactate permease
EXW57_RS06335	COG5634	Uncharacterized conserved protein (DUF2278)
EXW57_RS06370	COG2226	methyltransferase
EXW57_RS06390	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_RS06395	COG0567	Dehydrogenase, E1 component
EXW57_RS06400	COG1476	TRANSCRIPTIONal
EXW57_RS06500	COG0582	viral genome integration into host DNA
EXW57_RS06520	COG1686	Belongs to the peptidase S11 family
EXW57_RS06525	COG0681	Belongs to the peptidase S26 family
EXW57_RS06560	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS06570	COG1176	ABC-type spermidine putrescine transport system, permease component I
EXW57_RS06575	COG1177	transmembrane transport
EXW57_RS06580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EXW57_RS06590	COG2409	Drug exporters of the RND superfamily
EXW57_RS06600	COG0564	pseudouridine synthase activity
EXW57_RS06610	COG2340	Cysteine-rich secretory protein family
EXW57_RS06615	COG0247	lactate metabolic process
EXW57_RS06620	COG0277	FAD linked oxidase domain protein
EXW57_RS06625	COG3835	regulator
EXW57_RS06635	COG0745	RESPONSE REGULATOR receiver
EXW57_RS06640	COG5002	protein histidine kinase activity
EXW57_RS06645	COG2186	Transcriptional regulator
EXW57_RS06650	COG0247	lactate metabolic process
EXW57_RS06655	COG1139	Iron-sulfur cluster binding protein
EXW57_RS06660	COG1556	Lactate utilization protein
EXW57_RS06665	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EXW57_RS06675	COG2116	formate transmembrane transporter activity
EXW57_RS06680	COG0861	Integral membrane protein TerC family
EXW57_RS06685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW57_RS06695	COG2030	dehydratase
EXW57_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS06720	COG3243	poly(R)-hydroxyalkanoic acid synthase
EXW57_RS06730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EXW57_RS06745	COG1840	ABC-type Fe3 transport system, periplasmic component
EXW57_RS06750	COG3842	ATPase activity
EXW57_RS06760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW57_RS06765	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW57_RS06775	COG1349	DNA-binding transcription factor activity
EXW57_RS06785	COG0235	Class ii aldolase
EXW57_RS06795	COG2861	carbohydrate metabolic process
EXW57_RS06805	COG3852	Histidine kinase
EXW57_RS06810	COG1846	Transcriptional regulator
EXW57_RS06820	COG2318	DinB family
EXW57_RS06825	COG5002	protein histidine kinase activity
EXW57_RS06830	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EXW57_RS06835	COG0720	synthase
EXW57_RS06845	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EXW57_RS06850	COG4873	Protein conserved in bacteria
EXW57_RS06865	COG0456	acetyltransferase
EXW57_RS06880	COG1780	Probably involved in ribonucleotide reductase function
EXW57_RS06895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EXW57_RS06900	COG0531	amino acid
EXW57_RS06905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW57_RS06920	COG2204	response regulator
EXW57_RS06925	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS06935	COG1725	Transcriptional regulator
EXW57_RS06940	COG1131	(ABC) transporter
EXW57_RS06950	COG1131	(ABC) transporter
EXW57_RS06955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_RS06960	COG1266	CAAX protease self-immunity
EXW57_RS06970	COG1522	sequence-specific DNA binding
EXW57_RS06980	COG1335	isochorismatase
EXW57_RS06990	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_RS06995	COG2070	2-Nitropropane dioxygenase
EXW57_RS07000	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW57_RS07005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_RS07010	COG1696	Membrane protein involved in D-alanine export
EXW57_RS07035	COG0716	FMN binding
EXW57_RS07070	COG0534	Mate efflux family protein
EXW57_RS07075	COG1968	undecaprenyl-diphosphatase activity
EXW57_RS07095	COG1846	Transcriptional regulator
EXW57_RS07105	COG1301	dicarboxylic acid transport
EXW57_RS07120	COG3874	Sporulation protein YtfJ
EXW57_RS07140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS07145	COG0028	Belongs to the TPP enzyme family
EXW57_RS07150	COG0440	acetolactate synthase activity
EXW57_RS07160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW57_RS07170	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EXW57_RS07180	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EXW57_RS07185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EXW57_RS07195	COG0131	Imidazoleglycerol-phosphate dehydratase
EXW57_RS07200	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EXW57_RS07205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EXW57_RS07210	COG0107	imidazoleglycerol-phosphate synthase activity
EXW57_RS07220	COG0140	phosphoribosyl-ATP diphosphatase activity
EXW57_RS07225	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW57_RS07240	COG1183	phosphatidylcholine synthase activity
EXW57_RS07245	COG1368	sulfuric ester hydrolase activity
EXW57_RS07255	COG0019	diaminopimelate decarboxylase activity
EXW57_RS07265	COG0175	sulfate reduction
EXW57_RS07270	COG2046	Belongs to the sulfate adenylyltransferase family
EXW57_RS07275	COG0529	Catalyzes the synthesis of activated sulfate
EXW57_RS07280	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW57_RS07300	COG1648	precorrin-2 dehydrogenase activity
EXW57_RS07305	COG0733	neurotransmitter:sodium symporter activity
EXW57_RS07330	COG1757	Na H antiporter
EXW57_RS07345	COG4758	membrane
EXW57_RS07350	COG4585	Histidine kinase
EXW57_RS07355	COG2197	response regulator
EXW57_RS07365	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS07375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EXW57_RS07415	COG0730	response to heat
EXW57_RS07420	COG0306	phosphate transporter
EXW57_RS07425	COG1392	Phosphate transport regulator
EXW57_RS07430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS07445	COG3852	Histidine kinase
EXW57_RS07450	COG1801	Protein of unknown function DUF72
EXW57_RS07460	COG0582	viral genome integration into host DNA
EXW57_RS07465	COG5002	protein histidine kinase activity
EXW57_RS07480	COG0392	lysyltransferase activity
EXW57_RS07480	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EXW57_RS07495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_RS07500	COG1686	Belongs to the peptidase S11 family
EXW57_RS07505	COG2715	membrane protein required for spore maturation
EXW57_RS07510	COG0700	Nucleoside recognition
EXW57_RS07515	COG1187	pseudouridine synthase activity
EXW57_RS07525	COG1333	cytochrome c biogenesis protein
EXW57_RS07530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW57_RS07535	COG0745	RESPONSE REGULATOR receiver
EXW57_RS07540	COG5002	protein histidine kinase activity
EXW57_RS07545	COG2096	Adenosyltransferase
EXW57_RS07550	COG4942	peptidase
EXW57_RS07560	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EXW57_RS07565	COG1141	Ferredoxin
EXW57_RS07570	COG4955	Helix-turn-helix domain
EXW57_RS07575	COG0514	ATP-dependent DNA helicase (RecQ)
EXW57_RS07580	COG1266	CAAX protease self-immunity
EXW57_RS07590	COG1408	metallophosphoesterase
EXW57_RS07605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EXW57_RS07625	COG0492	ferredoxin-NADP+ reductase activity
EXW57_RS07630	COG0252	asparaginase activity
EXW57_RS07640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EXW57_RS07650	COG1304	FMN binding
EXW57_RS07685	COG1160	GTP binding
EXW57_RS07690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EXW57_RS07710	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_RS07720	COG0302	gtp cyclohydrolase
EXW57_RS07725	COG0142	geranyltranstransferase activity
EXW57_RS07730	COG2226	methyltransferase
EXW57_RS07735	COG0142	geranyltranstransferase activity
EXW57_RS07750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EXW57_RS07760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EXW57_RS07765	COG0457	Tetratricopeptide repeat
EXW57_RS07770	COG5582	Belongs to the UPF0302 family
EXW57_RS07785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EXW57_RS07800	COG4347	Protein of unknown function (DUF1405)
EXW57_RS07815	COG2738	Putative neutral zinc metallopeptidase
EXW57_RS07825	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS07830	COG1694	Mazg nucleotide pyrophosphohydrolase
EXW57_RS07835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EXW57_RS07840	COG1803	Methylglyoxal synthase
EXW57_RS07845	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_RS07850	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS07855	COG0617	tRNA 3'-terminal CCA addition
EXW57_RS07865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EXW57_RS07870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EXW57_RS07880	COG1199	ATP-dependent helicase activity
EXW57_RS07880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EXW57_RS07900	COG3935	DnaD domain protein
EXW57_RS07905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EXW57_RS07915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS07915	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_RS07920	COG3331	DNA recombination
EXW57_RS07955	COG4474	Belongs to the UPF0398 family
EXW57_RS07960	COG3599	regulation of cell shape
EXW57_RS07970	COG0116	Belongs to the methyltransferase superfamily
EXW57_RS07980	COG1199	ATP-dependent helicase activity
EXW57_RS07985	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EXW57_RS07995	COG0024	Methionine aminopeptidase
EXW57_RS08005	COG2233	PERMEase
EXW57_RS08010	COG2311	Membrane
EXW57_RS08015	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_RS08025	COG0456	acetyltransferase
EXW57_RS08035	COG2897	thiosulfate sulfurtransferase activity
EXW57_RS08075	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_RS08090	COG0454	-acetyltransferase
EXW57_RS08110	COG0328	RNA-DNA hybrid ribonuclease activity
EXW57_RS08145	COG3403	YqcI/YcgG family
EXW57_RS08150	COG1280	lysine exporter protein (LysE YggA)
EXW57_RS08165	COG3162	membrane
EXW57_RS08170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EXW57_RS08175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_RS08185	COG0475	glutathione-regulated potassium exporter activity
EXW57_RS08190	COG4978	Transcriptional regulator
EXW57_RS08190	COG0789	Transcriptional regulator
EXW57_RS08200	COG2323	membrane
EXW57_RS08205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EXW57_RS08235	COG2814	Major facilitator Superfamily
EXW57_RS08255	COG1923	regulation of RNA biosynthetic process
EXW57_RS08265	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW57_RS08270	COG1360	Flagellar Motor Protein
EXW57_RS08275	COG2201	protein-glutamate methylesterase activity
EXW57_RS08280	COG2198	Histidine kinase
EXW57_RS08280	COG0643	Histidine kinase
EXW57_RS08285	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_RS08285	COG1776	CheC inhibitor of MCP methylation
EXW57_RS08300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EXW57_RS08320	COG1256	bacterial-type flagellum assembly
EXW57_RS08325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_RS08345	COG1815	bacterial-type flagellum-dependent cell motility
EXW57_RS08350	COG1558	bacterial-type flagellum-dependent cell motility
EXW57_RS08360	COG1766	The M ring may be actively involved in energy transduction
EXW57_RS08365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_RS08375	COG1157	protein secretion by the type III secretion system
EXW57_RS08395	COG1749	Flagellar hook protein flgE
EXW57_RS08410	COG0784	Response regulator, receiver
EXW57_RS08410	COG0835	chemotaxis
EXW57_RS08430	COG0861	Integral membrane protein TerC family
EXW57_RS08440	COG3383	formate dehydrogenase (NAD+) activity
EXW57_RS08445	COG2427	Protein of unknown function (DUF1641)
EXW57_RS08450	COG5609	conserved protein (DUF2294)
EXW57_RS08455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EXW57_RS08465	COG2116	formate transmembrane transporter activity
EXW57_RS08470	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_RS08475	COG0303	'Molybdopterin
EXW57_RS08480	COG0314	molybdopterin synthase activity
EXW57_RS08485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EXW57_RS08495	COG0489	protein tyrosine kinase activity
EXW57_RS08500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_RS08500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EXW57_RS08505	COG0741	lytic transglycosylase activity
EXW57_RS08515	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_RS08520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EXW57_RS08520	COG1776	CheC inhibitor of MCP methylation
EXW57_RS08530	COG1338	Plays a role in the flagellum-specific transport system
EXW57_RS08535	COG1987	bacterial-type flagellum assembly
EXW57_RS08545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW57_RS08550	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EXW57_RS08555	COG1419	protein localization to endoplasmic reticulum
EXW57_RS08560	COG4786	Flagellar basal body rod
EXW57_RS08595	COG0412	Dienelactone hydrolase
EXW57_RS08600	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_RS08615	COG2814	Major facilitator Superfamily
EXW57_RS08625	COG0583	DNA-binding transcription factor activity
EXW57_RS08630	COG3842	ATPase activity
EXW57_RS08680	COG0406	alpha-ribazole phosphatase activity
EXW57_RS08710	COG0367	asparagine synthase
EXW57_RS08740	COG1802	Transcriptional regulator
EXW57_RS08745	COG0697	spore germination
EXW57_RS08755	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS08755	COG1216	Glycosyl transferase, family 2
EXW57_RS08760	COG1757	Na H antiporter
EXW57_RS08770	COG0277	FAD linked oxidase domain protein
EXW57_RS08790	COG0534	Mate efflux family protein
EXW57_RS08795	COG3340	Belongs to the peptidase S51 family
EXW57_RS08815	COG0785	Cytochrome C biogenesis protein
EXW57_RS08820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS08830	COG1917	Cupin 2, conserved barrel domain protein
EXW57_RS08835	COG3048	D-serine ammonia-lyase activity
EXW57_RS08840	COG2733	membrane
EXW57_RS08875	COG1131	(ABC) transporter
EXW57_RS08890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS08895	COG0528	UMP kinase activity
EXW57_RS08905	COG1027	Aspartate ammonia-lyase
EXW57_RS08910	COG0281	malic enzyme
EXW57_RS08915	COG4191	Histidine kinase
EXW57_RS08920	COG0784	Response regulator, receiver
EXW57_RS08925	COG1846	Transcriptional regulator
EXW57_RS08935	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_RS08945	COG2502	aspartate--ammonia ligase
EXW57_RS08980	COG1051	belongs to the nudix hydrolase family
EXW57_RS08985	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS08995	COG2814	Major facilitator Superfamily
EXW57_RS09020	COG1695	Transcriptional regulator
EXW57_RS09030	COG2814	Major facilitator Superfamily
EXW57_RS09035	COG0640	Transcriptional regulator
EXW57_RS09040	COG0477	Major facilitator Superfamily
EXW57_RS09045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_RS09055	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW57_RS09060	COG2223	nitrite transmembrane transporter activity
EXW57_RS09065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_RS09080	COG2244	polysaccharide biosynthetic process
EXW57_RS09085	COG0733	neurotransmitter:sodium symporter activity
EXW57_RS09095	COG5566	PFAM Mor transcription activator
EXW57_RS09100	COG2323	membrane
EXW57_RS09115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_RS09125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS09130	COG0028	Belongs to the TPP enzyme family
EXW57_RS09145	COG0129	dihydroxy-acid dehydratase activity
EXW57_RS09150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EXW57_RS09175	COG2814	Major facilitator Superfamily
EXW57_RS09180	COG3384	dioxygenase
EXW57_RS09205	COG4166	transmembrane transport
EXW57_RS09230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS09250	COG1914	H( )-stimulated, divalent metal cation uptake system
EXW57_RS09255	COG1054	Belongs to the UPF0176 family
EXW57_RS09265	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW57_RS09270	COG0531	amino acid
EXW57_RS09305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW57_RS09320	COG4257	antibiotic catabolic process
EXW57_RS09325	COG2390	Transcriptional regulator
EXW57_RS09335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EXW57_RS09340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS09345	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EXW57_RS09360	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW57_RS09375	COG0583	DNA-binding transcription factor activity
EXW57_RS09395	COG0006	proline dipeptidase activity
EXW57_RS09400	COG2132	Multicopper oxidase
EXW57_RS09410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW57_RS09420	COG0583	DNA-binding transcription factor activity
EXW57_RS09440	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS09450	COG1276	copper resistance
EXW57_RS09450	COG2372	response to copper ion
EXW57_RS09455	COG4549	nuclear export factor GLE1
EXW57_RS09465	COG0697	spore germination
EXW57_RS09470	COG0583	DNA-binding transcription factor activity
EXW57_RS09475	COG1959	2 iron, 2 sulfur cluster binding
EXW57_RS09480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EXW57_RS09485	COG0778	Nitroreductase
EXW57_RS09505	COG0628	permease
EXW57_RS09520	COG1231	oxidoreductase activity
EXW57_RS09525	COG0523	cobalamin synthesis protein
EXW57_RS09535	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS09540	COG2030	dehydratase
EXW57_RS09545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_RS09560	COG0411	ABC transporter
EXW57_RS09580	COG0583	DNA-binding transcription factor activity
EXW57_RS09590	COG1942	4-Oxalocrotonate Tautomerase
EXW57_RS09605	COG0346	lactoylglutathione lyase activity
EXW57_RS09615	COG1271	oxidase subunit
EXW57_RS09620	COG1294	oxidase, subunit
EXW57_RS09625	COG4988	ABC transporter
EXW57_RS09630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EXW57_RS09660	COG1686	Belongs to the peptidase S11 family
EXW57_RS09675	COG1388	LysM domain
EXW57_RS09675	COG0791	NLP P60 protein
EXW57_RS09685	COG1132	(ABC) transporter
EXW57_RS09690	COG0745	RESPONSE REGULATOR receiver
EXW57_RS09695	COG5002	protein histidine kinase activity
EXW57_RS09700	COG0300	oxidoreductase activity
EXW57_RS09705	COG4122	O-methyltransferase activity
EXW57_RS09735	COG0460	homoserine dehydrogenase
EXW57_RS09745	COG0083	homoserine kinase activity
EXW57_RS09760	COG1316	TRANSCRIPTIONal
EXW57_RS09780	COG1285	pathogenesis
EXW57_RS09785	COG1247	-acetyltransferase
EXW57_RS09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_RS09815	COG1082	Xylose isomerase domain protein TIM barrel
EXW57_RS09825	COG2814	Major facilitator Superfamily
EXW57_RS09830	COG1279	arginine transmembrane transporter activity
EXW57_RS09835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS09845	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW57_RS09875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EXW57_RS09880	COG0577	efflux transmembrane transporter activity
EXW57_RS09885	COG2002	toxin-antitoxin pair type II binding
EXW57_RS09890	COG1404	Belongs to the peptidase S8 family
EXW57_RS09895	COG0640	Transcriptional regulator
EXW57_RS09900	COG0667	Aldo Keto reductase
EXW57_RS09905	COG2814	Major facilitator Superfamily
EXW57_RS09945	COG3949	Membrane
EXW57_RS09950	COG0783	Belongs to the Dps family
EXW57_RS09965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EXW57_RS09975	COG1231	oxidoreductase activity
EXW57_RS09980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS09985	COG4989	oxidoreductase activity
EXW57_RS09990	COG0523	cobalamin synthesis protein
EXW57_RS09995	COG0456	acetyltransferase
EXW57_RS10000	COG0803	Belongs to the bacterial solute-binding protein 9 family
EXW57_RS10020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW57_RS10030	COG4166	transmembrane transport
EXW57_RS10035	COG0346	lactoylglutathione lyase activity
EXW57_RS10045	COG0406	alpha-ribazole phosphatase activity
EXW57_RS10055	COG5337	Spore coat protein CotH
EXW57_RS10060	COG1051	belongs to the nudix hydrolase family
EXW57_RS10065	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS10070	COG2244	polysaccharide biosynthetic process
EXW57_RS10080	COG0701	Predicted permease
EXW57_RS10085	COG3689	TIGRFAM TIGR03943 family protein
EXW57_RS10090	COG1607	acyl-coa hydrolase
EXW57_RS10100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS10115	COG0702	epimerase
EXW57_RS10120	COG2839	Protein conserved in bacteria
EXW57_RS10125	COG1253	flavin adenine dinucleotide binding
EXW57_RS10140	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS10145	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_RS10160	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS10170	COG1876	peptidase activity
EXW57_RS10200	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS10210	COG0561	phosphatase activity
EXW57_RS10220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EXW57_RS10240	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS10245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS10270	COG0456	acetyltransferase
EXW57_RS10305	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_RS10380	COG3874	Sporulation protein YtfJ
EXW57_RS10405	COG2226	methyltransferase
EXW57_RS10440	COG1595	DNA-templated transcription, initiation
EXW57_RS10475	COG0386	Belongs to the glutathione peroxidase family
EXW57_RS10480	COG1305	Transglutaminase-like
EXW57_RS10485	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
EXW57_RS10490	COG0714	Associated with various cellular activities
EXW57_RS10495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EXW57_RS10500	COG1140	nitrate reductase beta subunit
EXW57_RS10505	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EXW57_RS10510	COG2181	nitrate reductase activity
EXW57_RS10515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW57_RS10520	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW57_RS10525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_RS10530	COG0303	'Molybdopterin
EXW57_RS10535	COG0314	molybdopterin synthase activity
EXW57_RS10545	COG2223	nitrite transmembrane transporter activity
EXW57_RS10565	COG1648	precorrin-2 dehydrogenase activity
EXW57_RS10575	COG1587	Uroporphyrinogen-III synthase
EXW57_RS10575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EXW57_RS10580	COG2146	nitrite reductase [NAD(P)H] activity
EXW57_RS10585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EXW57_RS10590	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EXW57_RS10620	COG2359	stage V sporulation protein S
EXW57_RS10660	COG1418	mRNA catabolic process
EXW57_RS10665	COG0488	(ABC) transporter
EXW57_RS10685	COG1413	lyase activity
EXW57_RS10700	COG2521	methyltransferase
EXW57_RS10700	COG2136	Putative SAM-dependent methyltransferase
EXW57_RS10705	COG0018	arginyl-trna synthetase
EXW57_RS10755	COG0017	Asparaginyl-tRNA synthetase
EXW57_RS10760	COG0733	neurotransmitter:sodium symporter activity
EXW57_RS10785	COG2610	gluconate transmembrane transporter activity
EXW57_RS10795	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_RS10805	COG0456	acetyltransferase
EXW57_RS10810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EXW57_RS10820	COG1131	(ABC) transporter
EXW57_RS10825	COG4473	ABC transporter
EXW57_RS10835	COG0546	phosphoglycolate phosphatase activity
EXW57_RS10850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS10865	COG0768	penicillin binding
EXW57_RS10875	COG0204	Acyl-transferase
EXW57_RS10880	COG1272	protein, Hemolysin III
EXW57_RS10885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EXW57_RS10890	COG0805	protein transport
EXW57_RS10905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EXW57_RS10910	COG1999	signal sequence binding
EXW57_RS10915	COG0071	Belongs to the small heat shock protein (HSP20) family
EXW57_RS10920	COG0367	asparagine synthase
EXW57_RS10935	COG0860	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS10940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS10945	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS10960	COG1335	isochorismatase
EXW57_RS10970	COG0668	transmembrane transport
EXW57_RS10975	COG4585	Histidine kinase
EXW57_RS10975	COG2203	Gaf domain
EXW57_RS10980	COG2197	response regulator
EXW57_RS10985	COG1737	Transcriptional regulator
EXW57_RS10990	COG1064	alcohol dehydrogenase
EXW57_RS11005	COG1070	Carbohydrate kinase
EXW57_RS11015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW57_RS11035	COG1125	glycine betaine transport
EXW57_RS11035	COG0517	IMP dehydrogenase activity
EXW57_RS11040	COG1174	glycine betaine transport
EXW57_RS11075	COG1253	flavin adenine dinucleotide binding
EXW57_RS11080	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS11085	COG5506	Protein of unknown function (DUF1694)
EXW57_RS11100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_RS11105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EXW57_RS11110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EXW57_RS11115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_RS11120	COG0456	acetyltransferase
EXW57_RS11125	COG3829	transcription factor binding
EXW57_RS11130	COG1509	lysine 2,3-aminomutase activity
EXW57_RS11140	COG4479	Belongs to the UPF0346 family
EXW57_RS11165	COG4991	sh3 domain protein
EXW57_RS11165	COG3064	Membrane
EXW57_RS11165	COG0515	serine threonine protein kinase
EXW57_RS11175	COG0671	phosphoesterase, PA-phosphatase related
EXW57_RS11180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_RS11185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS11240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EXW57_RS11270	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS11290	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_RS11290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS11310	COG0372	Belongs to the citrate synthase family
EXW57_RS11315	COG2079	MmgE PrpD family protein
EXW57_RS11320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EXW57_RS11325	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS11330	COG2084	Dehydrogenase
EXW57_RS11335	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS11340	COG1280	lysine exporter protein (LysE YggA)
EXW57_RS11345	COG1024	Enoyl-CoA hydratase
EXW57_RS11360	COG0420	3'-5' exonuclease activity
EXW57_RS11385	COG2223	nitrite transmembrane transporter activity
EXW57_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS11395	COG1169	isochorismate synthase
EXW57_RS11400	COG1021	2,3-dihydroxybenzoate-AMP ligase
EXW57_RS11405	COG1535	isochorismatase
EXW57_RS11405	COG3433	isochorismatase activity
EXW57_RS11410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EXW57_RS11415	COG3251	PFAM MbtH domain protein
EXW57_RS11420	COG2814	Major facilitator Superfamily
EXW57_RS11435	COG0776	regulation of translation
EXW57_RS11445	COG2318	DinB family
EXW57_RS11450	COG1115	amino acid carrier protein
EXW57_RS11465	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_RS11475	COG1187	pseudouridine synthase activity
EXW57_RS11480	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW57_RS11485	COG3655	Transcriptional regulator
EXW57_RS11495	COG1136	(ABC) transporter
EXW57_RS11505	COG0596	Alpha beta hydrolase
EXW57_RS11520	COG0028	Belongs to the TPP enzyme family
EXW57_RS11545	COG1253	flavin adenine dinucleotide binding
EXW57_RS11575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EXW57_RS11595	COG1846	Transcriptional regulator
EXW57_RS11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS11610	COG1309	transcriptional regulator
EXW57_RS11640	COG1247	-acetyltransferase
EXW57_RS11670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EXW57_RS11680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS11710	COG0583	DNA-binding transcription factor activity
EXW57_RS11715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW57_RS11730	COG0583	DNA-binding transcription factor activity
EXW57_RS11735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EXW57_RS11740	COG2258	MOSC domain
EXW57_RS11755	COG1132	(ABC) transporter
EXW57_RS11760	COG1132	(ABC) transporter
EXW57_RS11775	COG0189	ligase activity
EXW57_RS11800	COG1396	sequence-specific DNA binding
EXW57_RS11835	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EXW57_RS11840	COG1595	DNA-templated transcription, initiation
EXW57_RS11915	COG2755	lipolytic protein G-D-S-L family
EXW57_RS11915	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EXW57_RS11925	COG2169	Transcriptional regulator
EXW57_RS11935	COG0673	inositol 2-dehydrogenase activity
EXW57_RS11995	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EXW57_RS12000	COG2971	BadF BadG BcrA BcrD
EXW57_RS12010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EXW57_RS12050	COG1309	transcriptional regulator
EXW57_RS12065	COG1136	(ABC) transporter
EXW57_RS12070	COG3615	Tellurite resistance protein tehB
EXW57_RS12070	COG0500	methyltransferase
EXW57_RS12080	COG0693	protein deglycase activity
EXW57_RS12090	COG0588	phosphoglycerate mutase activity
EXW57_RS12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_RS12125	COG0110	maltose O-acetyltransferase activity
EXW57_RS12130	COG1136	(ABC) transporter
EXW57_RS12160	COG1136	(ABC) transporter
EXW57_RS12165	COG0577	efflux transmembrane transporter activity
EXW57_RS12185	COG1686	Belongs to the peptidase S11 family
EXW57_RS12210	COG0768	penicillin binding
EXW57_RS12215	COG0745	RESPONSE REGULATOR receiver
EXW57_RS12220	COG2205	protein histidine kinase activity
EXW57_RS12225	COG1136	(ABC) transporter
EXW57_RS12230	COG0577	efflux transmembrane transporter activity
EXW57_RS12240	COG1595	DNA-templated transcription, initiation
EXW57_RS12250	COG0768	penicillin binding
EXW57_RS12255	COG0768	penicillin binding
EXW57_RS12290	COG1252	NADH dehydrogenase
EXW57_RS12295	COG0425	Belongs to the sulfur carrier protein TusA family
EXW57_RS12295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS12310	COG0697	spore germination
EXW57_RS12335	COG3397	chitin binding
EXW57_RS12340	COG0823	Involved in the tonB-independent uptake of proteins
EXW57_RS12350	COG1408	metallophosphoesterase
EXW57_RS12360	COG1131	(ABC) transporter
EXW57_RS12370	COG1309	transcriptional regulator
EXW57_RS12380	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS12385	COG0439	Biotin carboxylase
EXW57_RS12390	COG0511	ligase activity, forming carbon-carbon bonds
EXW57_RS12395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EXW57_RS12400	COG1024	Enoyl-CoA hydratase
EXW57_RS12405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EXW57_RS12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_RS12490	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_RS12520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW57_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS12555	COG1733	regulation of RNA biosynthetic process
EXW57_RS12580	COG1309	transcriptional regulator
EXW57_RS12610	COG0697	spore germination
EXW57_RS12615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS12650	COG2323	membrane
EXW57_RS12665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS12670	COG0697	spore germination
EXW57_RS12690	COG0201	protein transport
EXW57_RS12700	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS12705	COG3227	Zinc metalloprotease (Elastase)
EXW57_RS12710	COG1523	belongs to the glycosyl hydrolase 13 family
EXW57_RS12725	COG0076	glutamate decarboxylase activity
EXW57_RS12730	COG0657	acetylesterase activity
EXW57_RS12735	COG1073	alpha beta
EXW57_RS12745	COG0577	efflux transmembrane transporter activity
EXW57_RS12750	COG1136	(ABC) transporter
EXW57_RS12780	COG5002	protein histidine kinase activity
EXW57_RS12785	COG0745	RESPONSE REGULATOR receiver
EXW57_RS12790	COG1011	Hydrolase
EXW57_RS12815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_RS12820	COG1183	phosphatidylcholine synthase activity
EXW57_RS12830	COG1132	(ABC) transporter
EXW57_RS12835	COG3961	Belongs to the TPP enzyme family
EXW57_RS12855	COG0322	excinuclease ABC activity
EXW57_RS12880	COG2318	DinB family
EXW57_RS12895	COG4667	esterase of the alpha-beta hydrolase superfamily
EXW57_RS12920	COG3878	Protein conserved in bacteria
EXW57_RS12945	COG1051	belongs to the nudix hydrolase family
EXW57_RS12950	COG0592	DNA-directed DNA polymerase activity
EXW57_RS12955	COG2816	NAD+ diphosphatase activity
EXW57_RS12965	COG2223	nitrite transmembrane transporter activity
EXW57_RS12975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS13005	COG0697	spore germination
EXW57_RS13010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS13020	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_RS13035	COG2814	Major facilitator Superfamily
EXW57_RS13075	COG0768	penicillin binding
EXW57_RS13080	COG0671	phosphoesterase, PA-phosphatase related
EXW57_RS13085	COG0604	alcohol dehydrogenase
EXW57_RS13090	COG5002	protein histidine kinase activity
EXW57_RS13095	COG0745	RESPONSE REGULATOR receiver
EXW57_RS13105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_RS13115	COG2205	protein histidine kinase activity
EXW57_RS13130	COG1122	ATPase activity
EXW57_RS13135	COG4720	Psort location CytoplasmicMembrane, score
EXW57_RS13140	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_RS13145	COG1819	glycosyl
EXW57_RS13155	COG0768	penicillin binding
EXW57_RS13160	COG5002	protein histidine kinase activity
EXW57_RS13165	COG0561	phosphatase activity
EXW57_RS13210	COG2124	cytochrome p450
EXW57_RS13255	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EXW57_RS13265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS13270	COG0460	homoserine dehydrogenase
EXW57_RS13290	COG0577	efflux transmembrane transporter activity
EXW57_RS13295	COG1136	(ABC) transporter
EXW57_RS13305	COG0488	(ABC) transporter
EXW57_RS13310	COG0667	Aldo Keto reductase
EXW57_RS13315	COG0583	DNA-binding transcription factor activity
EXW57_RS13320	COG2205	protein histidine kinase activity
EXW57_RS13325	COG0745	RESPONSE REGULATOR receiver
EXW57_RS13335	COG3773	Cell wall hydrolase
EXW57_RS13340	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
EXW57_RS13390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS13405	COG2959	enzyme of heme biosynthesis
EXW57_RS13430	COG3483	tryptophan 2,3-dioxygenase activity
EXW57_RS13435	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EXW57_RS13440	COG3844	kynureninase activity
EXW57_RS13445	COG1309	transcriptional regulator
EXW57_RS13460	COG3284	Transcriptional regulator
EXW57_RS13475	COG1349	DNA-binding transcription factor activity
EXW57_RS13495	COG1959	2 iron, 2 sulfur cluster binding
EXW57_RS13510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW57_RS13515	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_RS13520	COG0022	dehydrogenase e1 component
EXW57_RS13525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS13550	COG0456	acetyltransferase
EXW57_RS13550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_RS13585	COG4176	ABC-type proline glycine betaine transport system permease component
EXW57_RS13590	COG0517	IMP dehydrogenase activity
EXW57_RS13590	COG4175	Glycine betaine
EXW57_RS13615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EXW57_RS13620	COG2153	protein acetylation
EXW57_RS13625	COG3397	chitin binding
EXW57_RS13635	COG1819	glycosyl
EXW57_RS13650	COG2205	protein histidine kinase activity
EXW57_RS13655	COG2315	Protein conserved in bacteria
EXW57_RS13710	COG3973	AAA domain
EXW57_RS13720	COG2105	PFAM AIG2 family protein
EXW57_RS13725	COG0514	ATP-dependent DNA helicase (RecQ)
EXW57_RS13750	COG4637	Psort location Cytoplasmic, score
EXW57_RS13760	COG1227	inorganic diphosphatase activity
EXW57_RS13765	COG3397	chitin binding
EXW57_RS13770	COG2318	DinB family
EXW57_RS13790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EXW57_RS13795	COG1115	amino acid carrier protein
EXW57_RS13800	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS13805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EXW57_RS13815	COG3938	Belongs to the proline racemase family
EXW57_RS13820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_RS13860	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS13875	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EXW57_RS13880	COG4166	transmembrane transport
EXW57_RS13890	COG4948	Mandelate Racemase Muconate Lactonizing
EXW57_RS13910	COG0667	Aldo Keto reductase
EXW57_RS13950	COG2936	dipeptidyl-peptidase activity
EXW57_RS13960	COG0745	RESPONSE REGULATOR receiver
EXW57_RS13980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_RS13985	COG1164	Oligoendopeptidase f
EXW57_RS14000	COG1307	EDD domain protein, DegV family
EXW57_RS14025	COG1335	isochorismatase
EXW57_RS14040	COG2814	Major facilitator Superfamily
EXW57_RS14050	COG1664	Polymer-forming cytoskeletal
EXW57_RS14055	COG0789	Transcriptional regulator
EXW57_RS14060	COG4533	DNA binding
EXW57_RS14065	COG0477	Major facilitator Superfamily
EXW57_RS14065	COG2814	Major facilitator Superfamily
EXW57_RS14085	COG2261	transglycosylase associated protein
EXW57_RS14100	COG2226	methyltransferase
EXW57_RS14135	COG0436	Aminotransferase
EXW57_RS14140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EXW57_RS14170	COG1131	(ABC) transporter
EXW57_RS14175	COG2188	Transcriptional regulator
EXW57_RS14215	COG0628	permease
EXW57_RS14260	COG2746	aminoglycoside 3-N-acetyltransferase activity
EXW57_RS14270	COG0697	spore germination
EXW57_RS14275	COG2318	DinB family
EXW57_RS14320	COG2814	Major facilitator Superfamily
EXW57_RS14325	COG1368	sulfuric ester hydrolase activity
EXW57_RS14340	COG0488	(ABC) transporter
EXW57_RS14440	COG2409	Drug exporters of the RND superfamily
EXW57_RS14440	COG1033	growth of symbiont in host cell
EXW57_RS14445	COG1309	transcriptional regulator
EXW57_RS14465	COG0287	Prephenate dehydrogenase
EXW57_RS14480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EXW57_RS14480	COG1605	Chorismate mutase
EXW57_RS14515	COG3584	3D domain protein
EXW57_RS14515	COG1388	LysM domain
EXW57_RS14525	COG0346	lactoylglutathione lyase activity
EXW57_RS14535	COG0431	NADPH-dependent FMN reductase
EXW57_RS14560	COG0579	oxidoreductase
EXW57_RS14565	COG1879	ABC-type sugar transport system periplasmic component
EXW57_RS14575	COG1172	Belongs to the binding-protein-dependent transport system permease family
EXW57_RS14580	COG1129	ABC transporter
EXW57_RS14585	COG2390	Transcriptional regulator
EXW57_RS14605	COG2226	methyltransferase
EXW57_RS14625	COG2329	Antibiotic biosynthesis monooxygenase
EXW57_RS14655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS14660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EXW57_RS14665	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EXW57_RS14670	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_RS14675	COG3239	Fatty acid desaturase
EXW57_RS14700	COG3842	ATPase activity
EXW57_RS14725	COG1175	transmembrane transport
EXW57_RS14730	COG1349	DNA-binding transcription factor activity
EXW57_RS14740	COG3655	Transcriptional regulator
EXW57_RS14755	COG4377	Putative membrane peptidase family (DUF2324)
EXW57_RS14775	COG3279	Response regulator of the LytR AlgR family
EXW57_RS14790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS14795	COG0346	lactoylglutathione lyase activity
EXW57_RS14820	COG0714	Associated with various cellular activities
EXW57_RS14840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EXW57_RS14845	COG0753	catalase activity
EXW57_RS14855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EXW57_RS14875	COG0778	Nitroreductase
EXW57_RS14880	COG1846	Transcriptional regulator
EXW57_RS14915	COG1725	Transcriptional regulator
EXW57_RS14945	COG2207	Transcriptional regulator
EXW57_RS14950	COG0456	acetyltransferase
EXW57_RS14965	COG0697	spore germination
EXW57_RS14970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS15005	COG0814	amino acid
EXW57_RS15010	COG0697	spore germination
EXW57_RS15025	COG0642	Histidine kinase
EXW57_RS15030	COG0745	RESPONSE REGULATOR receiver
EXW57_RS15035	COG0596	Alpha beta hydrolase
EXW57_RS15045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_RS15045	COG0456	acetyltransferase
EXW57_RS15070	COG0730	response to heat
EXW57_RS15080	COG0833	amino acid
EXW57_RS15090	COG4335	DNA alkylation repair
EXW57_RS15115	COG0681	Belongs to the peptidase S26 family
EXW57_RS15120	COG0768	penicillin binding
EXW57_RS15135	COG3104	oligopeptide transport
EXW57_RS15140	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EXW57_RS15155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EXW57_RS15160	COG1984	allophanate hydrolase subunit 2
EXW57_RS15165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EXW57_RS15170	COG1414	Transcriptional regulator
EXW57_RS15185	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS15210	COG0640	Transcriptional regulator
EXW57_RS15220	COG3314	Sporulation integral membrane protein YlbJ
EXW57_RS15240	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW57_RS15245	COG0577	efflux transmembrane transporter activity
EXW57_RS15250	COG0577	efflux transmembrane transporter activity
EXW57_RS15255	COG1136	(ABC) transporter
EXW57_RS15290	COG0574	Belongs to the PEP-utilizing enzyme family
EXW57_RS15290	COG3848	Pyruvate phosphate dikinase
EXW57_RS15300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW57_RS15325	COG5002	protein histidine kinase activity
EXW57_RS15330	COG0745	RESPONSE REGULATOR receiver
EXW57_RS15340	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW57_RS15370	COG0798	PFAM Bile acid sodium symporter
EXW57_RS15375	COG0346	lactoylglutathione lyase activity
EXW57_RS15380	COG0640	Transcriptional regulator
EXW57_RS15395	COG2211	Major facilitator Superfamily
EXW57_RS15410	COG1309	transcriptional regulator
EXW57_RS15420	COG1522	sequence-specific DNA binding
EXW57_RS15440	COG0346	lactoylglutathione lyase activity
EXW57_RS15465	COG0745	RESPONSE REGULATOR receiver
EXW57_RS15470	COG3850	Histidine kinase
EXW57_RS15470	COG5002	protein histidine kinase activity
EXW57_RS15500	COG1073	alpha beta
EXW57_RS15505	COG0814	amino acid
EXW57_RS15510	COG1760	l-serine dehydratase
EXW57_RS15515	COG1760	l-serine dehydratase
EXW57_RS15525	COG5002	protein histidine kinase activity
EXW57_RS15530	COG0745	RESPONSE REGULATOR receiver
EXW57_RS15540	COG5002	protein histidine kinase activity
EXW57_RS15565	COG4977	sequence-specific DNA binding
EXW57_RS15605	COG2814	Major facilitator Superfamily
EXW57_RS15620	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EXW57_RS15640	COG1476	TRANSCRIPTIONal
EXW57_RS15650	COG2226	methyltransferase
EXW57_RS15665	COG1696	Membrane protein involved in D-alanine export
EXW57_RS15675	COG1690	Belongs to the RtcB family
EXW57_RS15690	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EXW57_RS15705	COG1136	(ABC) transporter
EXW57_RS15710	COG0577	efflux transmembrane transporter activity
EXW57_RS15730	COG3850	Histidine kinase
EXW57_RS15730	COG5002	protein histidine kinase activity
EXW57_RS15740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS15755	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_RS15775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EXW57_RS15810	COG2814	Major facilitator Superfamily
EXW57_RS15900	COG0477	Major facilitator Superfamily
EXW57_RS15915	COG1846	Transcriptional regulator
EXW57_RS15920	COG2814	Major facilitator Superfamily
EXW57_RS15960	COG0640	Transcriptional regulator
EXW57_RS15985	COG1329	Transcriptional regulator
EXW57_RS16040	COG5002	protein histidine kinase activity
EXW57_RS16055	COG1136	(ABC) transporter
EXW57_RS16070	COG1131	(ABC) transporter
EXW57_RS16150	COG0789	Transcriptional regulator
EXW57_RS16210	COG4187	Peptidase family M20/M25/M40
EXW57_RS16215	COG1414	Transcriptional regulator
EXW57_RS16220	COG0833	amino acid
EXW57_RS16230	COG2031	fatty acid transporter
EXW57_RS16240	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_RS16290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EXW57_RS16295	COG1288	antiporter activity
EXW57_RS16300	COG2356	endonuclease I
EXW57_RS16305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_RS16325	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EXW57_RS16345	COG1785	Belongs to the alkaline phosphatase family
EXW57_RS16350	COG0778	Nitroreductase
EXW57_RS16355	COG1733	regulation of RNA biosynthetic process
EXW57_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS16380	COG1131	(ABC) transporter
EXW57_RS16410	COG1011	Hydrolase
EXW57_RS16415	COG2365	Tyrosine phosphatase family
EXW57_RS16440	COG0346	lactoylglutathione lyase activity
EXW57_RS16445	COG1940	carbohydrate kinase activity
EXW57_RS16450	COG0738	Major facilitator superfamily
EXW57_RS16455	COG0110	maltose O-acetyltransferase activity
EXW57_RS16470	COG0628	permease
EXW57_RS16475	COG2261	transglycosylase associated protein
EXW57_RS16510	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
EXW57_RS16520	COG1253	flavin adenine dinucleotide binding
EXW57_RS16525	COG0789	Transcriptional regulator
EXW57_RS16535	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW57_RS16560	COG0697	spore germination
EXW57_RS16565	COG1357	PFAM Pentapeptide repeats (8 copies)
EXW57_RS16570	COG3813	Protein conserved in bacteria
EXW57_RS16575	COG2706	6-phosphogluconolactonase activity
EXW57_RS16580	COG1070	Carbohydrate kinase
EXW57_RS16590	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EXW57_RS16595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EXW57_RS16610	COG0814	amino acid
EXW57_RS16630	COG1393	Belongs to the ArsC family
EXW57_RS16640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS16655	COG0494	nUDIX hydrolase
EXW57_RS16670	COG0384	phenazine biosynthesis protein PhzF
EXW57_RS16680	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS16685	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_RS16690	COG1733	regulation of RNA biosynthetic process
EXW57_RS16705	COG1191	sigma factor activity
EXW57_RS16720	COG1876	peptidase activity
EXW57_RS16760	COG0741	lytic transglycosylase activity
EXW57_RS16785	COG5002	protein histidine kinase activity
EXW57_RS16825	COG0814	amino acid
EXW57_RS16850	COG1151	hydroxylamine reductase activity
EXW57_RS16875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS16885	COG2072	flavoprotein involved in K transport
EXW57_RS16930	COG1695	Transcriptional regulator
EXW57_RS16935	COG0604	alcohol dehydrogenase
EXW57_RS16940	COG1113	amino acid transport
EXW57_RS16950	COG2814	Major facilitator Superfamily
EXW57_RS16960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_RS16965	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS16975	COG0534	Mate efflux family protein
EXW57_RS16980	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS16985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EXW57_RS17000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_RS17005	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_RS17025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS17030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS17035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS17040	COG3739	integral membrane protein
EXW57_RS17060	COG0583	DNA-binding transcription factor activity
EXW57_RS17085	COG1193	negative regulation of DNA recombination
EXW57_RS17105	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EXW57_RS17110	COG1164	Oligoendopeptidase f
EXW57_RS17115	COG2957	Belongs to the agmatine deiminase family
EXW57_RS17135	COG3781	membrane
EXW57_RS17150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS17185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EXW57_RS17190	COG0640	Transcriptional regulator
EXW57_RS17195	COG0604	alcohol dehydrogenase
EXW57_RS17200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EXW57_RS17205	COG0457	Tetratricopeptide repeat
EXW57_RS17215	COG2808	Putative FMN-binding domain
EXW57_RS17220	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_RS17230	COG0277	FAD linked oxidase domain protein
EXW57_RS17250	COG1285	pathogenesis
EXW57_RS17260	COG2514	catechol 2,3-dioxygenase activity
EXW57_RS17265	COG2720	vancomycin resistance protein
EXW57_RS17290	COG1278	Cold shock
EXW57_RS17300	COG0716	FMN binding
EXW57_RS17310	COG0494	nUDIX hydrolase
EXW57_RS17330	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS17340	COG0165	Argininosuccinate lyase
EXW57_RS17355	COG4145	pantothenate transmembrane transporter activity
EXW57_RS17365	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS17370	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS17380	COG1657	PFAM Prenyltransferase squalene oxidase
EXW57_RS17385	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EXW57_RS17390	COG2962	Rard protein
EXW57_RS17395	COG3326	Membrane
EXW57_RS17400	COG0531	amino acid
EXW57_RS17435	COG2226	methyltransferase
EXW57_RS17440	COG4166	transmembrane transport
EXW57_RS17445	COG4166	transmembrane transport
EXW57_RS17450	COG4166	transmembrane transport
EXW57_RS17455	COG1316	TRANSCRIPTIONal
EXW57_RS17465	COG1595	DNA-templated transcription, initiation
EXW57_RS17475	COG1131	(ABC) transporter
EXW57_RS17495	COG0673	inositol 2-dehydrogenase activity
EXW57_RS17500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EXW57_RS17505	COG0187	DNA topoisomerase II activity
EXW57_RS17510	COG1832	CoA-binding protein
EXW57_RS17515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_RS17520	COG0745	RESPONSE REGULATOR receiver
EXW57_RS17530	COG1328	CTP reductase activity
EXW57_RS17540	COG4841	protein insertion into membrane
EXW57_RS17545	COG0824	Thioesterase
EXW57_RS17570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS17585	COG1132	(ABC) transporter
EXW57_RS17590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EXW57_RS17620	COG2211	Major facilitator Superfamily
EXW57_RS17630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW57_RS17645	COG0183	Belongs to the thiolase family
EXW57_RS17650	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS17655	COG1268	BioY protein
EXW57_RS17660	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS17665	COG1396	sequence-specific DNA binding
EXW57_RS17690	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EXW57_RS17710	COG0830	nickel cation binding
EXW57_RS17750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS17760	COG5002	protein histidine kinase activity
EXW57_RS17770	COG0400	carboxylic ester hydrolase activity
EXW57_RS17775	COG0346	lactoylglutathione lyase activity
EXW57_RS17780	COG0069	glutamate synthase activity
EXW57_RS17785	COG1902	pentaerythritol trinitrate reductase activity
EXW57_RS17795	COG1329	Transcriptional regulator
EXW57_RS17800	COG0010	Belongs to the arginase family
EXW57_RS17810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EXW57_RS17815	COG2986	histidine ammonia-lyase
EXW57_RS17825	COG2226	methyltransferase
EXW57_RS17850	COG4846	Membrane protein involved in cytochrome C biogenesis
EXW57_RS17855	COG0785	Cytochrome C biogenesis protein
EXW57_RS17865	COG1473	amidohydrolase
EXW57_RS17870	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_RS17875	COG1131	(ABC) transporter
EXW57_RS17885	COG0583	DNA-binding transcription factor activity
EXW57_RS17895	COG1346	cytolysis
EXW57_RS17910	COG0730	response to heat
EXW57_RS17920	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_RS17920	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS17940	COG1132	(ABC) transporter
EXW57_RS17945	COG1132	(ABC) transporter
EXW57_RS17950	COG3763	UPF0154 protein
EXW57_RS17970	COG3639	organic phosphonate transmembrane transporter activity
EXW57_RS17980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_RS17985	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS17995	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EXW57_RS18000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EXW57_RS18015	COG1695	Transcriptional regulator
EXW57_RS18020	COG1132	(ABC) transporter
EXW57_RS18050	COG0367	asparagine synthase
EXW57_RS18055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW57_RS18065	COG1181	Belongs to the D-alanine--D-alanine ligase family
EXW57_RS18070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EXW57_RS18075	COG3420	alginic acid biosynthetic process
EXW57_RS18075	COG5434	Belongs to the glycosyl hydrolase 28 family
EXW57_RS18100	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS18110	COG0463	Glycosyl transferase, family 2
EXW57_RS18110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EXW57_RS18115	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS18120	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS18125	COG1086	Polysaccharide biosynthesis protein
EXW57_RS18130	COG0489	protein tyrosine kinase activity
EXW57_RS18135	COG3944	biosynthesis protein
EXW57_RS18140	COG0174	glutamine synthetase
EXW57_RS18145	COG0789	Transcriptional regulator
EXW57_RS18150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EXW57_RS18155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EXW57_RS18160	COG2860	membrane
EXW57_RS18170	COG0464	growth
EXW57_RS18190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EXW57_RS18200	COG3584	3D domain protein
EXW57_RS18200	COG1388	LysM domain
EXW57_RS18205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_RS18205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW57_RS18205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EXW57_RS18210	COG1105	Belongs to the carbohydrate kinase PfkB family
EXW57_RS18215	COG1349	DNA-binding transcription factor activity
EXW57_RS18220	COG1979	alcohol dehydrogenase
EXW57_RS18225	COG2322	membrane
EXW57_RS18235	COG1113	amino acid transport
EXW57_RS18245	COG1473	amidohydrolase
EXW57_RS18250	COG1408	metallophosphoesterase
EXW57_RS18255	COG2116	formate transmembrane transporter activity
EXW57_RS18270	COG2217	Heavy metal translocating P-type atpase
EXW57_RS18275	COG2608	mercury ion transmembrane transporter activity
EXW57_RS18280	COG1937	Protein conserved in bacteria
EXW57_RS18310	COG4566	intracellular signal transduction
EXW57_RS18320	COG2819	hydrolase of the alpha beta superfamily
EXW57_RS18325	COG1120	ATPase activity
EXW57_RS18330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS18335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS18340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS18345	COG0708	Exodeoxyribonuclease III
EXW57_RS18350	COG2169	Transcriptional regulator
EXW57_RS18355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EXW57_RS18360	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EXW57_RS18365	COG2706	6-phosphogluconolactonase activity
EXW57_RS18370	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_RS18375	COG2364	Membrane
EXW57_RS18385	COG0346	lactoylglutathione lyase activity
EXW57_RS18390	COG5001	Diguanylate cyclase
EXW57_RS18390	COG3300	MHYT domain
EXW57_RS18430	COG1346	cytolysis
EXW57_RS18440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EXW57_RS18445	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_RS18445	COG0596	Alpha beta hydrolase
EXW57_RS18450	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EXW57_RS18460	COG2188	Transcriptional regulator
EXW57_RS18465	COG2723	6-phospho-beta-galactosidase activity
EXW57_RS18470	COG0823	Involved in the tonB-independent uptake of proteins
EXW57_RS18475	COG3773	Cell wall hydrolase
EXW57_RS18485	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EXW57_RS18495	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW57_RS18500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EXW57_RS18505	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EXW57_RS18515	COG4550	Control of competence regulator ComK, YlbF/YmcA
EXW57_RS18520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW57_RS18525	COG1013	pyruvate-flavodoxin oxidoreductase activity
EXW57_RS18530	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EXW57_RS18530	COG0674	pyruvate-flavodoxin oxidoreductase activity
EXW57_RS18540	COG2359	stage V sporulation protein S
EXW57_RS18545	COG1692	metallophosphoesterase
EXW57_RS18550	COG1418	mRNA catabolic process
EXW57_RS18555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EXW57_RS18560	COG1058	Belongs to the CinA family
EXW57_RS18560	COG1546	Belongs to the CinA family
EXW57_RS18565	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EXW57_RS18570	COG1426	Protein conserved in bacteria
EXW57_RS18585	COG0300	oxidoreductase activity
EXW57_RS18590	COG0612	Peptidase, M16
EXW57_RS18595	COG0612	Peptidase, M16
EXW57_RS18600	COG1079	Belongs to the binding-protein-dependent transport system permease family
EXW57_RS18605	COG4603	Belongs to the binding-protein-dependent transport system permease family
EXW57_RS18610	COG3845	ABC transporter
EXW57_RS18615	COG1744	ABC transporter substrate-binding protein PnrA-like
EXW57_RS18620	COG2188	Transcriptional regulator
EXW57_RS18630	COG1674	ftsk spoiiie
EXW57_RS18640	COG0740	serine-type endopeptidase activity
EXW57_RS18645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW57_RS18655	COG0527	aspartate kinase activity
EXW57_RS18660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EXW57_RS18665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW57_RS18670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW57_RS18675	COG1873	PFAM PRC-barrel domain
EXW57_RS18680	COG0612	Peptidase, M16
EXW57_RS18685	COG0726	polysaccharide deacetylase
EXW57_RS18690	COG1185	polyribonucleotide nucleotidyltransferase activity
EXW57_RS18700	COG0196	riboflavin kinase activity
EXW57_RS18710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EXW57_RS18715	COG1550	Protein conserved in bacteria
EXW57_RS18720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EXW57_RS18725	COG1358	cellular component organization or biogenesis
EXW57_RS18730	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EXW57_RS18735	COG0195	Participates in both transcription termination and antitermination
EXW57_RS18740	COG0779	Required for maturation of 30S ribosomal subunits
EXW57_RS18750	COG0442	prolyl-tRNA aminoacylation
EXW57_RS18755	COG0750	zinc metalloprotease
EXW57_RS18765	COG4589	Belongs to the CDS family
EXW57_RS18775	COG0233	cytoplasmic translational termination
EXW57_RS18780	COG0528	UMP kinase activity
EXW57_RS18785	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EXW57_RS18795	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW57_RS18800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EXW57_RS18805	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EXW57_RS18810	COG4974	Belongs to the 'phage' integrase family
EXW57_RS18815	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EXW57_RS18820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EXW57_RS18825	COG0758	DNA mediated transformation
EXW57_RS18830	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EXW57_RS18835	COG0045	succinate-CoA ligase (ADP-forming) activity
EXW57_RS18840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW57_RS18855	COG0335	large ribosomal subunit rRNA binding
EXW57_RS18860	COG0336	Belongs to the RNA methyltransferase TrmD family
EXW57_RS18865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EXW57_RS18870	COG1837	Belongs to the UPF0109 family
EXW57_RS18880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EXW57_RS18890	COG0552	protein localization to endoplasmic reticulum
EXW57_RS18895	COG1196	nuclear chromosome segregation
EXW57_RS18900	COG0571	ribonuclease III activity
EXW57_RS18905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EXW57_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS18915	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EXW57_RS18920	COG0416	fatty acid biosynthetic process
EXW57_RS18925	COG2050	protein possibly involved in aromatic compounds catabolism
EXW57_RS18925	COG1349	DNA-binding transcription factor activity
EXW57_RS18930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EXW57_RS18935	COG1461	Dihydroxyacetone kinase
EXW57_RS18940	COG1302	Protein conserved in bacteria
EXW57_RS18955	COG1564	THIamine pyrophosphokinase
EXW57_RS18960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EXW57_RS18970	COG0515	serine threonine protein kinase
EXW57_RS18970	COG2815	serine threonine protein kinase
EXW57_RS18975	COG0631	protein serine/threonine phosphatase activity
EXW57_RS18980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EXW57_RS18985	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EXW57_RS18985	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW57_RS18990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EXW57_RS18995	COG0242	peptide deformylase activity
EXW57_RS19000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EXW57_RS19005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EXW57_RS19010	COG1758	RNA polymerase activity
EXW57_RS19025	COG1561	YicC-like family, N-terminal region
EXW57_RS19030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW57_RS19040	COG0006	proline dipeptidase activity
EXW57_RS19060	COG3069	C4-dicarboxylate transmembrane transporter activity
EXW57_RS19070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EXW57_RS19080	COG0167	dihydroorotate dehydrogenase activity
EXW57_RS19085	COG0543	2 iron, 2 sulfur cluster binding
EXW57_RS19090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EXW57_RS19100	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EXW57_RS19105	COG0540	Belongs to the ATCase OTCase family
EXW57_RS19115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EXW57_RS19120	COG0564	pseudouridine synthase activity
EXW57_RS19125	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EXW57_RS19135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EXW57_RS19140	COG3599	regulation of cell shape
EXW57_RS19145	COG2302	S4 RNA-binding domain
EXW57_RS19150	COG0762	integral membrane protein
EXW57_RS19155	COG1799	cell septum assembly
EXW57_RS19160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EXW57_RS19170	COG1873	PFAM PRC-barrel domain
EXW57_RS19175	COG1191	sigma factor activity
EXW57_RS19180	COG1191	sigma factor activity
EXW57_RS19190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EXW57_RS19195	COG0849	cell division
EXW57_RS19200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EXW57_RS19215	COG0772	Belongs to the SEDS family
EXW57_RS19220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EXW57_RS19225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW57_RS19230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EXW57_RS19235	COG0768	penicillin binding
EXW57_RS19240	COG0768	penicillin binding
EXW57_RS19250	COG0275	rRNA processing
EXW57_RS19255	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EXW57_RS19260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EXW57_RS19265	COG0454	-acetyltransferase
EXW57_RS19275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EXW57_RS19280	COG1399	metal-binding, possibly nucleic acid-binding protein
EXW57_RS19285	COG1323	Belongs to the UPF0348 family
EXW57_RS19290	COG3480	Lon protease (S16) C-terminal proteolytic domain
EXW57_RS19295	COG1752	Esterase of the alpha-beta hydrolase superfamily
EXW57_RS19300	COG3314	Sporulation integral membrane protein YlbJ
EXW57_RS19310	COG0742	ribosomal rna small subunit methyltransferase
EXW57_RS19320	COG4471	UPF0298 protein
EXW57_RS19325	COG3679	Belongs to the UPF0342 family
EXW57_RS19330	COG0406	alpha-ribazole phosphatase activity
EXW57_RS19345	COG2340	Cysteine-rich secretory protein family
EXW57_RS19355	COG3336	cytochrome c oxidase
EXW57_RS19380	COG0109	protoheme IX farnesyltransferase activity
EXW57_RS19385	COG1612	heme a metabolic process
EXW57_RS19390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EXW57_RS19395	COG0772	Belongs to the SEDS family
EXW57_RS19400	COG4838	Belongs to the UPF0358 family
EXW57_RS19405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EXW57_RS19410	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EXW57_RS19420	COG4896	Protein conserved in bacteria
EXW57_RS19435	COG1217	gtp-binding protein TYPA
EXW57_RS19445	COG0483	inositol monophosphate 1-phosphatase activity
EXW57_RS19455	COG4493	Belongs to the UPF0637 family
EXW57_RS19460	COG4476	Belongs to the UPF0223 family
EXW57_RS19465	COG1982	Orn Lys Arg decarboxylase major
EXW57_RS19510	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_RS19515	COG0022	dehydrogenase e1 component
EXW57_RS19520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_RS19535	COG0561	phosphatase activity
EXW57_RS19540	COG5503	Protein of unknown function (DUF1447)
EXW57_RS19545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EXW57_RS19550	COG0569	domain protein
EXW57_RS19560	COG1473	amidohydrolase
EXW57_RS19565	COG2171	N-acyltransferase activity
EXW57_RS19570	COG0583	DNA-binding transcription factor activity
EXW57_RS19575	COG0517	IMP dehydrogenase activity
EXW57_RS19585	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
EXW57_RS19595	COG4703	Protein of unknown function (DUF1797)
EXW57_RS19610	COG2200	EAL domain
EXW57_RS19615	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS19620	COG1408	metallophosphoesterase
EXW57_RS19665	COG2814	Major facilitator Superfamily
EXW57_RS19675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EXW57_RS19685	COG3209	COG3209 Rhs family protein
EXW57_RS19695	COG2205	protein histidine kinase activity
EXW57_RS19705	COG0436	Aminotransferase
EXW57_RS19710	COG1609	Transcriptional regulator
EXW57_RS19715	COG3833	ABC-type maltose transport systems, permease component
EXW57_RS19720	COG1175	transmembrane transport
EXW57_RS19725	COG2182	Extracellular solute-binding protein
EXW57_RS19735	COG0366	Alpha amylase catalytic
EXW57_RS19740	COG3842	ATPase activity
EXW57_RS19780	COG0183	Belongs to the thiolase family
EXW57_RS19815	COG1695	Transcriptional regulator
EXW57_RS19820	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS19830	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EXW57_RS19835	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EXW57_RS19840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EXW57_RS19845	COG0436	Aminotransferase
EXW57_RS19850	COG1850	ribulose-bisphosphate carboxylase activity
EXW57_RS19855	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EXW57_RS19860	COG0235	Class ii aldolase
EXW57_RS19865	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EXW57_RS19880	COG2084	Dehydrogenase
EXW57_RS19890	COG2199	diguanylate cyclase activity
EXW57_RS19895	COG0778	Nitroreductase
EXW57_RS19920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EXW57_RS19920	COG1263	PTS System
EXW57_RS19920	COG2190	(PTS) system
EXW57_RS19925	COG3711	transcriptional antiterminator
EXW57_RS19935	COG2188	Transcriptional regulator
EXW57_RS19940	COG0363	glucosamine-6-phosphate deaminase activity
EXW57_RS19945	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EXW57_RS19955	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EXW57_RS19960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EXW57_RS19970	COG1547	Domain of unknown function (DUF309)
EXW57_RS19980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EXW57_RS19985	COG4086	secreted protein
EXW57_RS19990	COG0561	phosphatase activity
EXW57_RS19995	COG0697	spore germination
EXW57_RS20010	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_RS20050	COG1686	Belongs to the peptidase S11 family
EXW57_RS20055	COG1725	Transcriptional regulator
EXW57_RS20060	COG1131	(ABC) transporter
EXW57_RS20085	COG1846	Transcriptional regulator
EXW57_RS20100	COG0598	Magnesium transport protein CorA
EXW57_RS20115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EXW57_RS20125	COG4974	Belongs to the 'phage' integrase family
EXW57_RS20135	COG0735	belongs to the Fur family
EXW57_RS20140	COG1300	Membrane
EXW57_RS20160	COG0667	Aldo Keto reductase
EXW57_RS20165	COG0656	L-ascorbic acid biosynthetic process
EXW57_RS20170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EXW57_RS20170	COG0456	acetyltransferase
EXW57_RS20180	COG1525	nuclease
EXW57_RS20180	COG4085	toxin activity
EXW57_RS20180	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS20185	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EXW57_RS20195	COG0596	Alpha beta hydrolase
EXW57_RS20200	COG2056	Na+-H+ antiporter family
EXW57_RS20205	COG1609	Transcriptional regulator
EXW57_RS20210	COG0456	acetyltransferase
EXW57_RS20215	COG1073	alpha beta
EXW57_RS20230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW57_RS20230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EXW57_RS20235	COG0307	riboflavin synthase, alpha
EXW57_RS20240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW57_RS20240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EXW57_RS20255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EXW57_RS20260	COG4106	trans-aconitate 2-methyltransferase activity
EXW57_RS20265	COG2226	methyltransferase
EXW57_RS20265	COG1073	alpha beta
EXW57_RS20270	COG0156	8-amino-7-oxononanoate synthase activity
EXW57_RS20280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EXW57_RS20290	COG1757	Na H antiporter
EXW57_RS20295	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS20305	COG1522	sequence-specific DNA binding
EXW57_RS20340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EXW57_RS20350	COG0300	oxidoreductase activity
EXW57_RS20355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS20360	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_RS20365	COG1760	l-serine dehydratase
EXW57_RS20370	COG1760	l-serine dehydratase
EXW57_RS20380	COG1234	tRNA 3'-trailer cleavage
EXW57_RS20395	COG1285	pathogenesis
EXW57_RS20410	COG2195	Cleaves the N-terminal amino acid of tripeptides
EXW57_RS20415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS20430	COG1376	ErfK ybiS ycfS ynhG family protein
EXW57_RS20435	COG4129	membrane
EXW57_RS20440	COG1126	abc transporter atp-binding protein
EXW57_RS20445	COG0765	amino acid transport
EXW57_RS20450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EXW57_RS20465	COG2816	NAD+ diphosphatase activity
EXW57_RS20470	COG2323	membrane
EXW57_RS20475	COG0772	Belongs to the SEDS family
EXW57_RS20480	COG0508	dehydrogenase complex catalyzes the overall conversion of
EXW57_RS20485	COG0022	dehydrogenase e1 component
EXW57_RS20490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EXW57_RS20495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EXW57_RS20500	COG3426	butyrate kinase activity
EXW57_RS20510	COG0280	phosphate acetyltransferase
EXW57_RS20515	COG3290	protein histidine kinase activity
EXW57_RS20515	COG3829	transcription factor binding
EXW57_RS20525	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_RS20530	COG3093	addiction module antidote protein HigA
EXW57_RS20540	COG0745	RESPONSE REGULATOR receiver
EXW57_RS20545	COG0750	zinc metalloprotease
EXW57_RS20550	COG0497	DNA recombination
EXW57_RS20555	COG1438	arginine binding
EXW57_RS20560	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EXW57_RS20565	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EXW57_RS20570	COG0142	geranyltranstransferase activity
EXW57_RS20575	COG1722	exodeoxyribonuclease VII activity
EXW57_RS20580	COG1570	exodeoxyribonuclease VII activity
EXW57_RS20585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EXW57_RS20590	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EXW57_RS20595	COG1302	Protein conserved in bacteria
EXW57_RS20600	COG0439	Biotin carboxylase
EXW57_RS20605	COG0511	ligase activity, forming carbon-carbon bonds
EXW57_RS20650	COG3854	ATPases associated with a variety of cellular activities
EXW57_RS20670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EXW57_RS20675	COG0006	proline dipeptidase activity
EXW57_RS20680	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EXW57_RS20690	COG3872	metal-dependent enzyme
EXW57_RS20700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EXW57_RS20735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS20745	COG1609	Transcriptional regulator
EXW57_RS20755	COG2076	Multidrug Resistance protein
EXW57_RS20760	COG2076	Multidrug Resistance protein
EXW57_RS20795	COG1725	Transcriptional regulator
EXW57_RS20810	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW57_RS20815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EXW57_RS20820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EXW57_RS20825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_RS20850	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EXW57_RS20875	COG4970	Tfp pilus assembly protein FimT
EXW57_RS20885	COG1459	type II secretion system
EXW57_RS20890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EXW57_RS20945	COG0646	methionine synthase
EXW57_RS20945	COG1410	methionine synthase
EXW57_RS20950	COG0646	methionine synthase
EXW57_RS20950	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EXW57_RS20955	COG0626	cystathionine gamma-synthase activity
EXW57_RS20960	COG0626	cystathionine gamma-synthase activity
EXW57_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS20990	COG1940	carbohydrate kinase activity
EXW57_RS20995	COG4483	Protein conserved in bacteria
EXW57_RS21000	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EXW57_RS21005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EXW57_RS21010	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EXW57_RS21015	COG0704	Plays a role in the regulation of phosphate uptake
EXW57_RS21025	COG0581	inorganic phosphate transmembrane transporter activity
EXW57_RS21030	COG0573	inorganic phosphate transmembrane transporter activity
EXW57_RS21035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EXW57_RS21040	COG0768	penicillin binding
EXW57_RS21045	COG0477	Major facilitator Superfamily
EXW57_RS21050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_RS21070	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EXW57_RS21075	COG0735	belongs to the Fur family
EXW57_RS21080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EXW57_RS21085	COG1121	(ABC) transporter
EXW57_RS21090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS21100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EXW57_RS21115	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EXW57_RS21120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EXW57_RS21125	COG2384	SAM-dependent methyltransferase
EXW57_RS21130	COG2010	Cytochrome c
EXW57_RS21135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EXW57_RS21140	COG0358	DNA primase activity
EXW57_RS21150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EXW57_RS21155	COG0517	IMP dehydrogenase activity
EXW57_RS21160	COG1381	Involved in DNA repair and RecF pathway recombination
EXW57_RS21170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EXW57_RS21175	COG0295	cytidine deaminase activity
EXW57_RS21180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EXW57_RS21185	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EXW57_RS21190	COG1480	7TM receptor with intracellular HD hydrolase
EXW57_RS21195	COG1702	phosphate starvation-inducible protein PhoH
EXW57_RS21210	COG1610	YqeY-like protein
EXW57_RS21215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EXW57_RS21220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EXW57_RS21225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EXW57_RS21235	COG0484	heat shock protein binding
EXW57_RS21240	COG0443	Heat shock 70 kDa protein
EXW57_RS21250	COG1420	regulation of RNA biosynthetic process
EXW57_RS21255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EXW57_RS21260	COG1733	regulation of RNA biosynthetic process
EXW57_RS21265	COG0481	GTPase activity
EXW57_RS21275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EXW57_RS21280	COG0268	Binds directly to 16S ribosomal RNA
EXW57_RS21285	COG1466	dna polymerase III delta subunit
EXW57_RS21295	COG0658	competence protein
EXW57_RS21295	COG2333	competence protein COMEC
EXW57_RS21300	COG2131	deaminase
EXW57_RS21305	COG1555	photosystem II stabilization
EXW57_RS21305	COG1596	polysaccharide export
EXW57_RS21310	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EXW57_RS21315	COG2226	methyltransferase
EXW57_RS21320	COG0799	negative regulation of ribosome biogenesis
EXW57_RS21325	COG1713	HD superfamily hydrolase involved in NAD metabolism
EXW57_RS21330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EXW57_RS21335	COG1534	Rna-binding protein
EXW57_RS21340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EXW57_RS21345	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EXW57_RS21350	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EXW57_RS21360	COG0688	phosphatidylethanolamine metabolic process
EXW57_RS21370	COG1595	DNA-templated transcription, initiation
EXW57_RS21375	COG2357	RelA SpoT domain protein
EXW57_RS21385	COG1785	Belongs to the alkaline phosphatase family
EXW57_RS21395	COG2267	carboxylic ester hydrolase activity
EXW57_RS21430	COG1404	Belongs to the peptidase S8 family
EXW57_RS21435	COG3186	Phenylalanine-4-hydroxylase
EXW57_RS21440	COG2154	pterin-4-alpha-carbinolamine dehydratase
EXW57_RS21445	COG2514	catechol 2,3-dioxygenase activity
EXW57_RS21450	COG2259	Doxx family
EXW57_RS21490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS21500	COG1012	belongs to the aldehyde dehydrogenase family
EXW57_RS21500	COG1454	alcohol dehydrogenase
EXW57_RS21505	COG0626	cystathionine gamma-synthase activity
EXW57_RS21510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EXW57_RS21515	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EXW57_RS21520	COG2226	methyltransferase
EXW57_RS21535	COG0768	penicillin binding
EXW57_RS21540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EXW57_RS21545	COG0572	uridine kinase
EXW57_RS21550	COG0826	peptidase U32
EXW57_RS21555	COG0826	peptidase U32
EXW57_RS21560	COG4122	O-methyltransferase activity
EXW57_RS21565	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EXW57_RS21575	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EXW57_RS21580	COG4472	Bacterial protein of unknown function (DUF965)
EXW57_RS21585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EXW57_RS21595	COG0628	permease
EXW57_RS21615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EXW57_RS21625	COG0482	sulfurtransferase activity
EXW57_RS21630	COG1104	cysteine desulfurase activity
EXW57_RS21635	COG1959	2 iron, 2 sulfur cluster binding
EXW57_RS21640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EXW57_RS21650	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EXW57_RS21655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EXW57_RS21670	COG1490	D-aminoacyl-tRNA deacylase activity
EXW57_RS21675	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EXW57_RS21680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EXW57_RS21685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EXW57_RS21685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EXW57_RS21690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_RS21695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW57_RS21695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EXW57_RS21705	COG2244	polysaccharide biosynthetic process
EXW57_RS21710	COG2323	membrane
EXW57_RS21720	COG1862	Preprotein translocase
EXW57_RS21725	COG0343	queuine tRNA-ribosyltransferase activity
EXW57_RS21730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EXW57_RS21740	COG2255	four-way junction helicase activity
EXW57_RS21745	COG0632	four-way junction helicase activity
EXW57_RS21750	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EXW57_RS21775	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EXW57_RS21780	COG0157	Belongs to the NadC ModD family
EXW57_RS21785	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EXW57_RS21790	COG1104	cysteine desulfurase activity
EXW57_RS21795	COG1827	regulation of RNA biosynthetic process
EXW57_RS21800	COG2258	MOSC domain
EXW57_RS21805	COG0077	Prephenate dehydratase
EXW57_RS21810	COG0577	efflux transmembrane transporter activity
EXW57_RS21815	COG0577	efflux transmembrane transporter activity
EXW57_RS21820	COG1136	(ABC) transporter
EXW57_RS21825	COG5002	protein histidine kinase activity
EXW57_RS21830	COG0745	RESPONSE REGULATOR receiver
EXW57_RS21835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EXW57_RS21840	COG3290	protein histidine kinase activity
EXW57_RS21850	COG2868	ribosomal protein
EXW57_RS21860	COG1530	ribonuclease E activity
EXW57_RS21865	COG1994	Peptidase M50
EXW57_RS21870	COG0739	heme binding
EXW57_RS21875	COG2894	cell division
EXW57_RS21880	COG0850	regulation of cytokinetic process
EXW57_RS21895	COG1077	Cell shape determining protein MreB Mrl
EXW57_RS21900	COG2003	Belongs to the UPF0758 family
EXW57_RS21905	COG0424	maF-like protein
EXW57_RS21915	COG0285	dihydrofolate synthase activity
EXW57_RS21930	COG1388	LysM domain
EXW57_RS21935	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EXW57_RS21940	COG0113	porphobilinogen synthase activity
EXW57_RS21945	COG1587	Uroporphyrinogen-III synthase
EXW57_RS21950	COG0181	hydroxymethylbilane synthase activity
EXW57_RS21955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EXW57_RS21960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EXW57_RS21965	COG1846	Transcriptional regulator
EXW57_RS21970	COG1764	response to oxidative stress
EXW57_RS21975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EXW57_RS21985	COG0470	DNA polymerase III
EXW57_RS21985	COG1067	ATP-dependent peptidase activity
EXW57_RS21995	COG0544	peptidyl-prolyl cis-trans isomerase activity
EXW57_RS22025	COG0622	Phosphoesterase
EXW57_RS22035	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EXW57_RS22040	COG5401	PFAM Sporulation and spore germination
EXW57_RS22050	COG0477	Major facilitator Superfamily
EXW57_RS22055	COG2197	response regulator
EXW57_RS22060	COG2233	PERMEase
EXW57_RS22065	COG0402	S-adenosylhomocysteine deaminase activity
EXW57_RS22070	COG1983	PspC domain protein
EXW57_RS22075	COG1396	sequence-specific DNA binding
EXW57_RS22080	COG0697	spore germination
EXW57_RS22090	COG1959	2 iron, 2 sulfur cluster binding
EXW57_RS22095	COG1668	transmembrane transport
EXW57_RS22100	COG4152	abc transporter atp-binding protein
EXW57_RS22105	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EXW57_RS22110	COG1360	Flagellar Motor Protein
EXW57_RS22115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EXW57_RS22120	COG1876	peptidase activity
EXW57_RS22125	COG0824	Thioesterase
EXW57_RS22130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EXW57_RS22135	COG1053	succinate dehydrogenase
EXW57_RS22140	COG2009	succinate dehydrogenase
EXW57_RS22145	COG1719	4-vinyl reductase, 4VR
EXW57_RS22150	COG0322	excinuclease ABC activity
EXW57_RS22155	COG3118	belongs to the thioredoxin family
EXW57_RS22160	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EXW57_RS22165	COG2086	electron transfer activity
EXW57_RS22170	COG1024	Enoyl-CoA hydratase
EXW57_RS22175	COG1309	transcriptional regulator
EXW57_RS22180	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS22200	COG2318	DinB family
EXW57_RS22230	COG1131	(ABC) transporter
EXW57_RS22235	COG2205	protein histidine kinase activity
EXW57_RS22240	COG0745	RESPONSE REGULATOR receiver
EXW57_RS22250	COG4895	conserved protein (DUF2196)
EXW57_RS22255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EXW57_RS22265	COG4509	Sortase family
EXW57_RS22270	COG1120	ATPase activity
EXW57_RS22285	COG5386	Cell surface protein
EXW57_RS22295	COG5386	Cell surface protein
EXW57_RS22300	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS22310	COG1193	negative regulation of DNA recombination
EXW57_RS22315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EXW57_RS22315	COG1796	DNA polymerase
EXW57_RS22320	COG1286	toxin biosynthetic process
EXW57_RS22325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EXW57_RS22330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EXW57_RS22355	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EXW57_RS22360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EXW57_RS22370	COG1418	mRNA catabolic process
EXW57_RS22400	COG2814	Major facilitator Superfamily
EXW57_RS22405	COG1566	PFAM secretion protein HlyD family protein
EXW57_RS22410	COG1309	transcriptional regulator
EXW57_RS22415	COG1363	Peptidase, m42
EXW57_RS22425	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EXW57_RS22440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EXW57_RS22450	COG1484	DNA-dependent DNA replication
EXW57_RS22455	COG3611	Membrane attachment protein
EXW57_RS22460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EXW57_RS22465	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EXW57_RS22470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW57_RS22475	COG0237	dephospho-CoA kinase activity
EXW57_RS22480	COG1971	Probably functions as a manganese efflux pump
EXW57_RS22490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_RS22490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EXW57_RS22495	COG5002	protein histidine kinase activity
EXW57_RS22500	COG0745	RESPONSE REGULATOR receiver
EXW57_RS22515	COG0039	L-malate dehydrogenase activity
EXW57_RS22520	COG0538	isocitrate dehydrogenase activity
EXW57_RS22525	COG0372	Belongs to the citrate synthase family
EXW57_RS22535	COG0628	permease
EXW57_RS22540	COG3030	protein affecting phage T7 exclusion by the F plasmid
EXW57_RS22550	COG0205	6-phosphofructokinase activity
EXW57_RS22560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EXW57_RS22565	COG1725	Transcriptional regulator
EXW57_RS22570	COG0281	malic enzyme
EXW57_RS22575	COG0587	DNA-directed DNA polymerase activity
EXW57_RS22590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EXW57_RS22605	COG4109	DRTGG domain
EXW57_RS22620	COG0006	proline dipeptidase activity
EXW57_RS22650	COG0662	Cupin 2, conserved barrel domain protein
EXW57_RS22660	COG1476	TRANSCRIPTIONal
EXW57_RS22675	COG1028	Short-chain dehydrogenase reductase Sdr
EXW57_RS22680	COG0589	response to stress
EXW57_RS22710	COG0137	argininosuccinate synthase activity
EXW57_RS22725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS22745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EXW57_RS22750	COG0827	DNA restriction-modification system
EXW57_RS22755	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EXW57_RS22760	COG3874	Sporulation protein YtfJ
EXW57_RS22775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EXW57_RS22785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_RS22800	COG1104	cysteine desulfurase activity
EXW57_RS22805	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EXW57_RS22820	COG1309	transcriptional regulator
EXW57_RS22825	COG1956	GAF domain-containing protein
EXW57_RS22830	COG0626	cystathionine gamma-synthase activity
EXW57_RS22835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EXW57_RS22860	COG1595	DNA-templated transcription, initiation
EXW57_RS22870	COG0110	maltose O-acetyltransferase activity
EXW57_RS22875	COG0456	acetyltransferase
EXW57_RS22880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EXW57_RS22885	COG0454	-acetyltransferase
EXW57_RS22890	COG0517	IMP dehydrogenase activity
EXW57_RS22895	COG0123	including yeast histone deacetylase and acetoin utilization protein
EXW57_RS22910	COG0745	RESPONSE REGULATOR receiver
EXW57_RS22915	COG5002	protein histidine kinase activity
EXW57_RS22920	COG0666	response to abiotic stimulus
EXW57_RS22930	COG1970	mechanosensitive ion channel activity
EXW57_RS22950	COG1609	Transcriptional regulator
EXW57_RS22965	COG4851	CamS sex pheromone cAM373 precursor
EXW57_RS22970	COG3118	belongs to the thioredoxin family
EXW57_RS22980	COG2309	aminopeptidase activity
EXW57_RS23005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS23010	COG1695	Transcriptional regulator
EXW57_RS23020	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EXW57_RS23030	COG1674	ftsk spoiiie
EXW57_RS23045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_RS23050	COG4848	Belongs to the UPF0354 family
EXW57_RS23055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS23060	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EXW57_RS23065	COG1363	Peptidase, m42
EXW57_RS23075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS23080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EXW57_RS23090	COG0510	thiamine kinase activity
EXW57_RS23095	COG1523	belongs to the glycosyl hydrolase 13 family
EXW57_RS23105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EXW57_RS23110	COG1349	DNA-binding transcription factor activity
EXW57_RS23115	COG1187	pseudouridine synthase activity
EXW57_RS23120	COG2244	polysaccharide biosynthetic process
EXW57_RS23125	COG2081	HI0933 family
EXW57_RS23130	COG2814	Major facilitator Superfamily
EXW57_RS23140	COG3832	glyoxalase III activity
EXW57_RS23160	COG1329	Transcriptional regulator
EXW57_RS23185	COG0314	molybdopterin synthase activity
EXW57_RS23190	COG1763	Mo-molybdopterin cofactor biosynthetic process
EXW57_RS23195	COG0303	'Molybdopterin
EXW57_RS23200	COG0315	cyclic pyranopterin monophosphate synthase activity
EXW57_RS23205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EXW57_RS23210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EXW57_RS23230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EXW57_RS23240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EXW57_RS23280	COG0495	leucyl-tRNA aminoacylation
EXW57_RS23285	COG2814	Major facilitator Superfamily
EXW57_RS23290	COG0475	glutathione-regulated potassium exporter activity
EXW57_RS23295	COG0490	domain, Protein
EXW57_RS23300	COG0582	viral genome integration into host DNA
EXW57_RS23310	COG1136	(ABC) transporter
EXW57_RS23325	COG1242	4 iron, 4 sulfur cluster binding
EXW57_RS23330	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EXW57_RS23335	COG1131	(ABC) transporter
EXW57_RS23345	COG1794	racemase activity, acting on amino acids and derivatives
EXW57_RS23360	COG2267	carboxylic ester hydrolase activity
EXW57_RS23365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EXW57_RS23370	COG0671	phosphoesterase, PA-phosphatase related
EXW57_RS23375	COG0438	transferase activity, transferring glycosyl groups
EXW57_RS23385	COG0521	Mo-molybdopterin cofactor biosynthetic process
EXW57_RS23410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EXW57_RS23415	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EXW57_RS23455	COG5002	protein histidine kinase activity
EXW57_RS23460	COG3852	Histidine kinase
EXW57_RS23465	COG0753	catalase activity
EXW57_RS23470	COG2267	carboxylic ester hydrolase activity
EXW57_RS23480	COG1368	sulfuric ester hydrolase activity
EXW57_RS23490	COG4895	conserved protein (DUF2196)
EXW57_RS23505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EXW57_RS23510	COG1116	anion transmembrane transporter activity
EXW57_RS23515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EXW57_RS23540	COG0494	nUDIX hydrolase
EXW57_RS23575	COG2076	Multidrug Resistance protein
EXW57_RS23580	COG2076	Multidrug Resistance protein
EXW57_RS23585	COG0789	Transcriptional regulator
EXW57_RS23590	COG1854	S-ribosylhomocysteine lyase activity
EXW57_RS23600	COG0288	reversible hydration of carbon dioxide
EXW57_RS23605	COG1271	oxidase subunit
EXW57_RS23610	COG1294	oxidase, subunit
EXW57_RS23630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS23655	COG1842	Phage shock protein A
EXW57_RS23680	COG3859	Proton-coupled thiamine transporter YuaJ
EXW57_RS23685	COG5002	protein histidine kinase activity
EXW57_RS23690	COG0745	RESPONSE REGULATOR receiver
EXW57_RS23715	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EXW57_RS23720	COG1597	lipid kinase activity
EXW57_RS23750	COG1136	(ABC) transporter
EXW57_RS23780	COG5002	protein histidine kinase activity
EXW57_RS23790	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS23805	COG0577	efflux transmembrane transporter activity
EXW57_RS23810	COG1136	(ABC) transporter
EXW57_RS23815	COG2207	Transcriptional regulator
EXW57_RS23815	COG3708	Transcriptional regulator
EXW57_RS23825	COG1131	(ABC) transporter
EXW57_RS23835	COG5658	integral membrane protein
EXW57_RS23840	COG0640	Transcriptional regulator
EXW57_RS23845	COG0745	RESPONSE REGULATOR receiver
EXW57_RS23850	COG2205	protein histidine kinase activity
EXW57_RS23855	COG0577	efflux transmembrane transporter activity
EXW57_RS23860	COG0577	efflux transmembrane transporter activity
EXW57_RS23865	COG1136	(ABC) transporter
EXW57_RS23870	COG0577	efflux transmembrane transporter activity
EXW57_RS23885	COG2188	Transcriptional regulator
EXW57_RS23905	COG3964	amidohydrolase
EXW57_RS23925	COG4948	Mandelate Racemase Muconate Lactonizing
EXW57_RS23930	COG0318	PFAM AMP-dependent synthetase and ligase
EXW57_RS23940	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EXW57_RS23950	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EXW57_RS23955	COG1169	isochorismate synthase
EXW57_RS23960	COG1575	Belongs to the MenA family. Type 1 subfamily
EXW57_RS23965	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EXW57_RS23970	COG1278	Cold shock
EXW57_RS23980	COG0789	Transcriptional regulator
EXW57_RS23990	COG0058	SHG alpha-glucan phosphorylase activity
EXW57_RS24000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW57_RS24005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EXW57_RS24010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EXW57_RS24035	COG1595	DNA-templated transcription, initiation
EXW57_RS24170	COG1285	pathogenesis
EXW57_RS24175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EXW57_RS24185	COG0166	Belongs to the GPI family
EXW57_RS24190	COG2155	Conserved Protein
EXW57_RS24195	COG1098	S1 RNA binding domain
EXW57_RS24200	COG0436	Aminotransferase
EXW57_RS24205	COG1522	sequence-specific DNA binding
EXW57_RS24210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EXW57_RS24215	COG2267	carboxylic ester hydrolase activity
EXW57_RS24225	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EXW57_RS24245	COG5018	Exonuclease
EXW57_RS24250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_RS24270	COG2050	protein possibly involved in aromatic compounds catabolism
EXW57_RS24280	COG1268	BioY protein
EXW57_RS24285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW57_RS24290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EXW57_RS24300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EXW57_RS24305	COG3584	3D domain protein
EXW57_RS24320	COG1252	NADH dehydrogenase
EXW57_RS24325	COG0492	ferredoxin-NADP+ reductase activity
EXW57_RS24330	COG3708	Transcriptional regulator
EXW57_RS24345	COG1683	Conserved Protein
EXW57_RS24365	COG0316	Belongs to the HesB IscA family
EXW57_RS24370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EXW57_RS24375	COG4844	belongs to the
EXW57_RS24380	COG1252	NADH dehydrogenase
EXW57_RS24390	COG0390	transport system, permease component
EXW57_RS24395	COG2824	Alkylphosphonate utilization operon protein PhnA
EXW57_RS24425	COG4837	Protein of unknown function (DUF1462)
EXW57_RS24430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EXW57_RS24440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EXW57_RS24445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EXW57_RS24460	COG1136	(ABC) transporter
EXW57_RS24460	COG0577	efflux transmembrane transporter activity
EXW57_RS24465	COG2249	NAD(P)H dehydrogenase (quinone) activity
EXW57_RS24475	COG0647	UMP catabolic process
EXW57_RS24485	COG2445	Protein of unknown function DUF86
EXW57_RS24490	COG1494	fructose-1,6-bisphosphatase
EXW57_RS24505	COG4470	Protein conserved in bacteria
EXW57_RS24515	COG0789	Transcriptional regulator
EXW57_RS24520	COG4377	Putative membrane peptidase family (DUF2324)
EXW57_RS24540	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EXW57_RS24545	COG0739	heme binding
EXW57_RS24555	COG3377	Domain of unknown function (DUF1805)
EXW57_RS24560	COG0737	Belongs to the 5'-nucleotidase family
EXW57_RS24565	COG0719	Fe-S assembly protein
EXW57_RS24570	COG0822	iron-sulfur transferase activity
EXW57_RS24575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EXW57_RS24580	COG0719	Fe-S assembly protein
EXW57_RS24585	COG0396	ATPase activity
EXW57_RS24590	COG1464	Belongs to the NlpA lipoprotein family
EXW57_RS24595	COG1464	Belongs to the NlpA lipoprotein family
EXW57_RS24600	COG2011	ABC-type metal ion transport system permease component
EXW57_RS24605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EXW57_RS24615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EXW57_RS24620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EXW57_RS24625	COG0509	glycine decarboxylation via glycine cleavage system
EXW57_RS24630	COG1393	Belongs to the ArsC family
EXW57_RS24665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EXW57_RS24670	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS24675	COG0183	Belongs to the thiolase family
EXW57_RS24680	COG1024	Enoyl-CoA hydratase
EXW57_RS24680	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW57_RS24690	COG1686	Belongs to the peptidase S11 family
EXW57_RS24695	COG0506	proline dehydrogenase activity
EXW57_RS24705	COG0011	TIGRFAM Protein of
EXW57_RS24710	COG0840	transmembrane signaling receptor activity
EXW57_RS24730	COG2814	Major facilitator Superfamily
EXW57_RS24735	COG0531	amino acid
EXW57_RS24760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EXW57_RS24820	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS24830	COG1376	ErfK ybiS ycfS ynhG family protein
EXW57_RS24835	COG0745	RESPONSE REGULATOR receiver
EXW57_RS24840	COG5002	protein histidine kinase activity
EXW57_RS24850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EXW57_RS24860	COG0840	transmembrane signaling receptor activity
EXW57_RS24865	COG0840	transmembrane signaling receptor activity
EXW57_RS24870	COG2151	metal-sulfur cluster biosynthetic enzyme
EXW57_RS24875	COG3227	Zinc metalloprotease (Elastase)
EXW57_RS24880	COG1741	Belongs to the pirin family
EXW57_RS24895	COG0586	Pfam SNARE associated Golgi protein
EXW57_RS24900	COG0475	glutathione-regulated potassium exporter activity
EXW57_RS24905	COG0490	domain, Protein
EXW57_RS24910	COG1115	amino acid carrier protein
EXW57_RS24915	COG0783	Belongs to the Dps family
EXW57_RS24925	COG2318	DinB family
EXW57_RS24930	COG1611	Belongs to the LOG family
EXW57_RS24940	COG1528	Iron-storage protein
EXW57_RS24945	COG2311	Membrane
EXW57_RS24950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS24955	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS24960	COG1115	amino acid carrier protein
EXW57_RS24965	COG1115	amino acid carrier protein
EXW57_RS24970	COG2910	NAD(P)H-binding
EXW57_RS24980	COG0656	L-ascorbic acid biosynthetic process
EXW57_RS24985	COG2814	Major facilitator Superfamily
EXW57_RS24990	COG1733	regulation of RNA biosynthetic process
EXW57_RS25000	COG1252	NADH dehydrogenase
EXW57_RS25020	COG3290	protein histidine kinase activity
EXW57_RS25020	COG0840	transmembrane signaling receptor activity
EXW57_RS25030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EXW57_RS25050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS25065	COG4224	UPF0291 protein
EXW57_RS25070	COG1335	isochorismatase
EXW57_RS25075	COG1522	sequence-specific DNA binding
EXW57_RS25085	COG1522	sequence-specific DNA binding
EXW57_RS25090	COG0288	reversible hydration of carbon dioxide
EXW57_RS25095	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EXW57_RS25100	COG2233	PERMEase
EXW57_RS25140	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EXW57_RS25145	COG0557	exoribonuclease II activity
EXW57_RS25150	COG1647	Serine aminopeptidase, S33
EXW57_RS25155	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EXW57_RS25160	COG1346	cytolysis
EXW57_RS25175	COG0148	phosphopyruvate hydratase activity
EXW57_RS25185	COG0149	triose-phosphate isomerase activity
EXW57_RS25190	COG0126	phosphoglycerate kinase activity
EXW57_RS25195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EXW57_RS25210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EXW57_RS25245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EXW57_RS25260	COG2323	membrane
EXW57_RS25270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EXW57_RS25275	COG1481	regulation of sporulation
EXW57_RS25280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EXW57_RS25285	COG1660	Displays ATPase and GTPase activities
EXW57_RS25290	COG1051	belongs to the nudix hydrolase family
EXW57_RS25300	COG0492	ferredoxin-NADP+ reductase activity
EXW57_RS25305	COG0457	Tetratricopeptide repeat
EXW57_RS25310	COG0110	maltose O-acetyltransferase activity
EXW57_RS25315	COG0546	phosphoglycolate phosphatase activity
EXW57_RS25320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EXW57_RS25325	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EXW57_RS25330	COG1950	PFAM Membrane protein of
EXW57_RS25335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EXW57_RS25355	COG0789	Transcriptional regulator
EXW57_RS25390	COG0583	DNA-binding transcription factor activity
EXW57_RS25395	COG0789	Transcriptional regulator
EXW57_RS25400	COG0655	NAD(P)H dehydrogenase (quinone) activity
EXW57_RS25405	COG0488	(ABC) transporter
EXW57_RS25415	COG1132	(ABC) transporter
EXW57_RS25420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_RS25425	COG0793	Belongs to the peptidase S41A family
EXW57_RS25425	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_RS25430	COG2177	Part of the ABC transporter FtsEX involved in
EXW57_RS25435	COG2884	Cell division ATP-binding protein ftsE
EXW57_RS25460	COG1131	(ABC) transporter
EXW57_RS25495	COG1278	Cold shock
EXW57_RS25500	COG1040	competence protein
EXW57_RS25505	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EXW57_RS25520	COG0791	NLP P60 protein
EXW57_RS25520	COG1388	LysM domain
EXW57_RS25525	COG1733	regulation of RNA biosynthetic process
EXW57_RS25530	COG1307	EDD domain protein, DegV family
EXW57_RS25535	COG1739	Uncharacterized protein family UPF0029
EXW57_RS25540	COG1316	TRANSCRIPTIONal
EXW57_RS25545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EXW57_RS25550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EXW57_RS25555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EXW57_RS25565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
EXW57_RS25565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EXW57_RS25585	COG1486	melibiose metabolic process
EXW57_RS25590	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_RS25595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_RS25615	COG1447	Phosphotransferase system cellobiose-specific component IIA
EXW57_RS25625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EXW57_RS25630	COG1301	dicarboxylic acid transport
EXW57_RS25645	COG1511	domain protein
EXW57_RS25650	COG0583	DNA-binding transcription factor activity
EXW57_RS25655	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EXW57_RS25665	COG1271	oxidase subunit
EXW57_RS25670	COG1294	oxidase, subunit
EXW57_RS25675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EXW57_RS25680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EXW57_RS25685	COG1620	l-lactate permease
EXW57_RS25695	COG2389	metal-binding protein
EXW57_RS25705	COG1368	sulfuric ester hydrolase activity
EXW57_RS25715	COG0791	NLP P60 protein
EXW57_RS25715	COG1388	LysM domain
EXW57_RS25720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EXW57_RS25730	COG1215	transferase activity, transferring glycosyl groups
EXW57_RS25735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW57_RS25740	COG1388	LysM domain
EXW57_RS25740	COG3584	3D domain protein
EXW57_RS25765	COG4715	Zinc finger, swim domain protein
EXW57_RS25770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EXW57_RS25810	COG0577	efflux transmembrane transporter activity
EXW57_RS25815	COG1136	(ABC) transporter
EXW57_RS25850	COG5002	protein histidine kinase activity
EXW57_RS25850	COG3850	Histidine kinase
EXW57_RS25855	COG0745	RESPONSE REGULATOR receiver
EXW57_RS25860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW57_RS25880	COG1216	Glycosyl transferase, family 2
EXW57_RS25880	COG1442	glycosyl transferase family 8
EXW57_RS25915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EXW57_RS25920	COG1086	Polysaccharide biosynthesis protein
EXW57_RS25925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EXW57_RS25930	COG4464	protein tyrosine phosphatase activity
EXW57_RS25935	COG0489	protein tyrosine kinase activity
EXW57_RS25940	COG3944	biosynthesis protein
EXW57_RS25945	COG0489	protein tyrosine kinase activity
EXW57_RS25960	COG1609	Transcriptional regulator
EXW57_RS25970	COG0739	heme binding
EXW57_RS25985	COG3279	Response regulator of the LytR AlgR family
EXW57_RS25990	COG2385	sporulation resulting in formation of a cellular spore
EXW57_RS26005	COG4836	Membrane
EXW57_RS26010	COG1007	ATP synthesis coupled electron transport
EXW57_RS26015	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_RS26020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EXW57_RS26025	COG0713	ATP synthesis coupled electron transport
EXW57_RS26030	COG0839	Belongs to the complex I subunit 6 family
EXW57_RS26040	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EXW57_RS26045	COG0649	NAD binding
EXW57_RS26050	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_RS26055	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_RS26060	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EXW57_RS26065	COG5001	Diguanylate cyclase
EXW57_RS26065	COG3300	MHYT domain
EXW57_RS26080	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EXW57_RS26085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EXW57_RS26090	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EXW57_RS26095	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EXW57_RS26100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EXW57_RS26105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EXW57_RS26115	COG0356	it plays a direct role in the translocation of protons across the membrane
EXW57_RS26140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EXW57_RS26150	COG0698	ribose 5-phosphate isomerase
EXW57_RS26160	COG2190	(PTS) system
EXW57_RS26165	COG2259	Doxx family
EXW57_RS26170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EXW57_RS26180	COG1971	Probably functions as a manganese efflux pump
EXW57_RS26185	COG0009	L-threonylcarbamoyladenylate synthase
EXW57_RS26200	COG2890	protein-(glutamine-N5) methyltransferase activity
EXW57_RS26205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EXW57_RS26210	COG1435	thymidine kinase activity
EXW57_RS26220	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EXW57_RS26225	COG1494	fructose-1,6-bisphosphatase
EXW57_RS26245	COG4821	SIS domain
EXW57_RS26250	COG0504	CTP synthase activity
EXW57_RS26255	COG3343	RNA polymerase activity
EXW57_RS26265	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS26270	COG1960	acyl-CoA dehydrogenase activity
EXW57_RS26275	COG1250	3-hydroxyacyl-CoA dehydrogenase
EXW57_RS26280	COG0183	Belongs to the thiolase family
EXW57_RS26285	COG0247	lactate metabolic process
EXW57_RS26285	COG2181	nitrate reductase activity
EXW57_RS26290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS26295	COG4294	response to UV
EXW57_RS26300	COG5001	Diguanylate cyclase
EXW57_RS26300	COG3300	MHYT domain
EXW57_RS26315	COG3227	Zinc metalloprotease (Elastase)
EXW57_RS26320	COG2197	response regulator
EXW57_RS26325	COG4585	Histidine kinase
EXW57_RS26330	COG0842	Transport permease protein
EXW57_RS26335	COG1131	(ABC) transporter
EXW57_RS26340	COG0024	Methionine aminopeptidase
EXW57_RS26345	COG2234	aminopeptidase activity
EXW57_RS26360	COG4506	Protein conserved in bacteria
EXW57_RS26365	COG1619	proteins homologs of microcin C7 resistance protein MccF
EXW57_RS26380	COG0010	Belongs to the arginase family
EXW57_RS26385	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EXW57_RS26390	COG2814	Major facilitator Superfamily
EXW57_RS26395	COG0789	Transcriptional regulator
EXW57_RS26400	COG0584	glycerophosphoryl diester phosphodiesterase
EXW57_RS26405	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS26415	COG1994	Peptidase M50
EXW57_RS26425	COG1078	dGTPase activity
EXW57_RS26430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EXW57_RS26435	COG1120	ATPase activity
EXW57_RS26440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS26445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EXW57_RS26450	COG4844	belongs to the
EXW57_RS26465	COG0280	phosphate acetyltransferase
EXW57_RS26470	COG3253	May function as heme-dependent peroxidase
EXW57_RS26480	COG3773	Cell wall hydrolase
EXW57_RS26490	COG2363	Small membrane protein
EXW57_RS26505	COG2233	PERMEase
EXW57_RS26510	COG0561	phosphatase activity
EXW57_RS26515	COG2814	Major facilitator Superfamily
EXW57_RS26520	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EXW57_RS26525	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EXW57_RS26530	COG1131	(ABC) transporter
EXW57_RS26535	COG2755	lipolytic protein G-D-S-L family
EXW57_RS26540	COG1609	Transcriptional regulator
EXW57_RS26550	COG0460	homoserine dehydrogenase
EXW57_RS26555	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EXW57_RS26560	COG2873	o-acetylhomoserine
EXW57_RS26575	COG2197	response regulator
EXW57_RS26580	COG4585	Histidine kinase
EXW57_RS26580	COG2203	Gaf domain
EXW57_RS26585	COG0351	phosphomethylpyrimidine kinase
EXW57_RS26590	COG3706	GGDEF domain
EXW57_RS26595	COG2879	small protein
EXW57_RS26600	COG1966	Carbon starvation protein
EXW57_RS26605	COG3279	Response regulator of the LytR AlgR family
EXW57_RS26610	COG0477	Major facilitator Superfamily
EXW57_RS26635	COG0840	transmembrane signaling receptor activity
EXW57_RS26645	COG1607	acyl-coa hydrolase
EXW57_RS26650	COG1216	Glycosyl transferase, family 2
EXW57_RS26660	COG1216	Glycosyl transferase, family 2
EXW57_RS26670	COG4485	Bacterial membrane protein, YfhO
EXW57_RS26675	COG0463	Glycosyl transferase, family 2
EXW57_RS26685	COG1309	transcriptional regulator
EXW57_RS26690	COG0488	(ABC) transporter
EXW57_RS26695	COG1309	transcriptional regulator
EXW57_RS26700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EXW57_RS26705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_RS26705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EXW57_RS26710	COG0628	permease
EXW57_RS26720	COG1380	Effector of murein hydrolase LrgA
EXW57_RS26725	COG3279	Response regulator of the LytR AlgR family
EXW57_RS26730	COG3275	phosphorelay sensor kinase activity
EXW57_RS26735	COG2814	Major facilitator Superfamily
EXW57_RS26740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EXW57_RS26745	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EXW57_RS26750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EXW57_RS26800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EXW57_RS26805	COG1272	protein, Hemolysin III
EXW57_RS26830	COG1164	Oligoendopeptidase f
EXW57_RS26840	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EXW57_RS26850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_RS26855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EXW57_RS26860	COG4853	Protein conserved in bacteria
EXW57_RS26870	COG5002	protein histidine kinase activity
EXW57_RS26875	COG0745	RESPONSE REGULATOR receiver
EXW57_RS26905	COG0305	Participates in initiation and elongation during chromosome replication
EXW57_RS26910	COG0359	binds to the 23S rRNA
EXW57_RS26915	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
EXW57_RS26920	COG4241	membrane
EXW57_RS26930	COG0629	single-stranded DNA binding
EXW57_RS26935	COG0360	Binds together with S18 to 16S ribosomal RNA
EXW57_RS26940	COG0012	GTP binding
EXW57_RS26945	COG4481	Protein conserved in bacteria
EXW57_RS26950	COG0668	transmembrane transport
EXW57_RS26960	COG1475	DNA binding
EXW57_RS26965	COG1192	Involved in chromosome partitioning
EXW57_RS26970	COG1475	DNA binding
EXW57_RS26975	COG0357	Ribosomal RNA small subunit methyltransferase G
EXW57_RS26980	COG0445	tRNA wobble uridine modification
EXW57_RS26985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EXW57_RS26990	COG1847	R3H domain protein
EXW57_RS26995	COG0706	membrane insertase activity
EXW57_RS27000	COG0594	ribonuclease P activity
EXW57_RS27005	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EXW57_RS27020	COG1278	Cold shock
EXW57_RS27025	COG0662	Cupin 2, conserved barrel domain protein
EXW57_RS27060	COG0582	viral genome integration into host DNA
EXW57_RS27090	COG0488	(ABC) transporter
EXW57_RS27100	COG1136	(ABC) transporter
EXW57_RS27105	COG0577	efflux transmembrane transporter activity
EXW57_RS27120	COG5002	protein histidine kinase activity
EXW57_RS27160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EXW57_RS27175	COG1674	ftsk spoiiie
EXW57_RS27185	COG0741	lytic transglycosylase activity
EXW57_RS27195	COG5002	protein histidine kinase activity
EXW57_RS27200	COG0745	RESPONSE REGULATOR receiver
EXW57_RS27210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EXW57_RS27215	COG0577	efflux transmembrane transporter activity
EXW57_RS27220	COG1136	(ABC) transporter
EXW57_RS27355	COG2040	homocysteine
EXW57_RS27360	COG0833	amino acid
EXW57_RS27435	COG0658	competence protein
EXW57_RS27435	COG2333	competence protein COMEC
EXW57_RS27450	COG0825	malonyl-CoA metabolic process
EXW57_RS27455	COG0640	Transcriptional regulator
EXW57_RS27475	COG0519	Catalyzes the synthesis of GMP from XMP
EXW57_RS27535	COG1115	amino acid carrier protein
EXW57_RS27540	COG1114	Component of the transport system for branched-chain amino acids
EXW57_RS27545	COG3409	Peptidoglycan-binding domain 1 protein
EXW57_RS27545	COG5632	N-Acetylmuramoyl-L-alanine amidase
EXW57_RS27550	COG2239	Acts as a magnesium transporter
EXW57_RS27560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EXW57_RS27575	COG0697	spore germination
EXW57_RS27625	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS27635	COG0662	Cupin 2, conserved barrel domain protein
EXW57_RS27650	COG0583	DNA-binding transcription factor activity
EXW57_RS27670	COG4974	Belongs to the 'phage' integrase family
EXW57_RS27725	COG2211	Major facilitator Superfamily
EXW57_RS27750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EXW57_RS27760	COG2239	Acts as a magnesium transporter
EXW57_RS27765	COG0772	Belongs to the SEDS family
EXW57_RS27770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EXW57_RS27775	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EXW57_RS27825	COG0697	spore germination
EXW57_RS27840	COG0662	Cupin 2, conserved barrel domain protein
EXW57_RS27850	COG0814	amino acid
EXW57_RS27855	COG1760	l-serine dehydratase
EXW57_RS27860	COG1760	l-serine dehydratase
EXW57_RS27870	COG0697	spore germination
EXW57_RS27875	COG0814	amino acid
EXW57_RS27890	COG1595	DNA-templated transcription, initiation
EXW57_RS27965	COG0686	Belongs to the AlaDH PNT family
EXW57_RS27970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EXW57_RS27970	COG2508	Transcriptional regulator
EXW57_RS27980	COG2814	Major facilitator Superfamily
EXW57_RS27985	COG1309	transcriptional regulator
EXW57_RS28000	COG0083	homoserine kinase activity
EXW57_RS28045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EXW57_RS28070	COG2814	Major facilitator Superfamily
EXW57_RS28140	COG1329	Transcriptional regulator
EXW57_RS28195	COG4176	ABC-type proline glycine betaine transport system permease component
EXW57_RS28200	COG0517	IMP dehydrogenase activity
EXW57_RS28200	COG4175	Glycine betaine
EXW57_RS28220	COG2205	protein histidine kinase activity
EXW57_RS28225	COG0745	RESPONSE REGULATOR receiver
EXW57_RS28230	COG0577	efflux transmembrane transporter activity
EXW57_RS28235	COG1136	(ABC) transporter
EXW57_RS28270	COG4499	WXG100 protein secretion system (Wss), protein YukC
EXW57_RS28270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EXW57_RS28280	COG0772	Belongs to the SEDS family
EXW57_RS28290	COG0741	lytic transglycosylase activity
EXW57_RS28310	COG0577	efflux transmembrane transporter activity
EXW57_RS28315	COG1136	(ABC) transporter
EXW57_RS28330	COG0789	Transcriptional regulator
EXW57_RS28340	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EXW57_RS28345	COG1923	regulation of RNA biosynthetic process
EXW57_RS28355	COG2002	toxin-antitoxin pair type II binding
EXW57_RS28555	COG1396	sequence-specific DNA binding
EXW57_RS28575	COG2186	Transcriptional regulator
EXW57_RS28770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS28775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EXW57_RS28905	COG5002	protein histidine kinase activity