locus-tag	class	description
E1A90_RS00005	COG4974	Belongs to the 'phage' integrase family
E1A90_RS00010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E1A90_RS00025	COG2076	Multidrug Resistance protein
E1A90_RS00030	COG2076	Multidrug Resistance protein
E1A90_RS00035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E1A90_RS00040	COG1073	alpha beta
E1A90_RS00055	COG0772	Belongs to the SEDS family
E1A90_RS00065	COG2239	Acts as a magnesium transporter
E1A90_RS00075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E1A90_RS00085	COG2162	N-hydroxyarylamine O-acetyltransferase activity
E1A90_RS00105	COG0745	RESPONSE REGULATOR receiver
E1A90_RS00135	COG4974	Belongs to the 'phage' integrase family
E1A90_RS00155	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS00240	COG0745	RESPONSE REGULATOR receiver
E1A90_RS00245	COG5002	protein histidine kinase activity
E1A90_RS00250	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A90_RS00275	COG2040	homocysteine
E1A90_RS00280	COG0833	amino acid
E1A90_RS00295	COG1942	4-Oxalocrotonate Tautomerase
E1A90_RS00300	COG0583	DNA-binding transcription factor activity
E1A90_RS00310	COG1846	Transcriptional regulator
E1A90_RS00320	COG1136	(ABC) transporter
E1A90_RS00335	COG0741	lytic transglycosylase activity
E1A90_RS00355	COG1674	ftsk spoiiie
E1A90_RS00370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
E1A90_RS00395	COG1533	DNA photolyase activity
E1A90_RS00430	COG2155	Conserved Protein
E1A90_RS00455	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A90_RS00510	COG0756	dUTP diphosphatase activity
E1A90_RS00585	COG1695	Transcriptional regulator
E1A90_RS00595	COG2732	(Barnase) inhibitor
E1A90_RS00625	COG0653	protein targeting
E1A90_RS00735	COG2814	Major facilitator Superfamily
E1A90_RS00740	COG0583	DNA-binding transcription factor activity
E1A90_RS00775	COG0577	efflux transmembrane transporter activity
E1A90_RS00780	COG1136	(ABC) transporter
E1A90_RS00800	COG0463	Glycosyl transferase, family 2
E1A90_RS00810	COG0745	RESPONSE REGULATOR receiver
E1A90_RS00815	COG5002	protein histidine kinase activity
E1A90_RS00840	COG0640	Transcriptional regulator
E1A90_RS00880	COG0456	acetyltransferase
E1A90_RS00910	COG4176	ABC-type proline glycine betaine transport system permease component
E1A90_RS00915	COG4175	Glycine betaine
E1A90_RS00915	COG0517	IMP dehydrogenase activity
E1A90_RS00945	COG0456	acetyltransferase
E1A90_RS00960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A90_RS00960	COG4499	WXG100 protein secretion system (Wss), protein YukC
E1A90_RS01025	COG4641	Protein conserved in bacteria
E1A90_RS01030	COG2089	acid synthase
E1A90_RS01045	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
E1A90_RS01050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E1A90_RS01060	COG1086	Polysaccharide biosynthesis protein
E1A90_RS01065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1A90_RS01070	COG0463	Glycosyl transferase, family 2
E1A90_RS01075	COG0463	Glycosyl transferase, family 2
E1A90_RS01270	COG2169	Transcriptional regulator
E1A90_RS01275	COG0673	inositol 2-dehydrogenase activity
E1A90_RS01280	COG0673	inositol 2-dehydrogenase activity
E1A90_RS01355	COG2169	Transcriptional regulator
E1A90_RS01360	COG0673	inositol 2-dehydrogenase activity
E1A90_RS01365	COG0673	inositol 2-dehydrogenase activity
E1A90_RS01405	COG2323	membrane
E1A90_RS01440	COG0456	acetyltransferase
E1A90_RS01450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E1A90_RS01455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A90_RS01460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E1A90_RS01475	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1A90_RS01510	COG1404	Belongs to the peptidase S8 family
E1A90_RS01610	COG0542	response to heat
E1A90_RS01635	COG0367	asparagine synthase
E1A90_RS01640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
E1A90_RS01720	COG1396	sequence-specific DNA binding
E1A90_RS01785	COG0457	Tetratricopeptide repeat
E1A90_RS01920	COG0457	Tetratricopeptide repeat
E1A90_RS01980	COG0662	Cupin 2, conserved barrel domain protein
E1A90_RS02000	COG2197	response regulator
E1A90_RS02060	COG0823	Involved in the tonB-independent uptake of proteins
E1A90_RS02095	COG2239	Acts as a magnesium transporter
E1A90_RS02130	COG0697	spore germination
E1A90_RS02145	COG1252	NADH dehydrogenase
E1A90_RS02150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS02150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A90_RS02155	COG2002	toxin-antitoxin pair type II binding
E1A90_RS02165	COG1923	regulation of RNA biosynthetic process
E1A90_RS02215	COG2814	Major facilitator Superfamily
E1A90_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS02385	COG1923	regulation of RNA biosynthetic process
E1A90_RS02435	COG5001	Diguanylate cyclase
E1A90_RS02435	COG3300	MHYT domain
E1A90_RS02440	COG0346	lactoylglutathione lyase activity
E1A90_RS02455	COG2195	Cleaves the N-terminal amino acid of tripeptides
E1A90_RS02460	COG2706	6-phosphogluconolactonase activity
E1A90_RS02470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E1A90_RS02475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E1A90_RS02480	COG2169	Transcriptional regulator
E1A90_RS02485	COG0708	Exodeoxyribonuclease III
E1A90_RS02490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS02495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS02500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS02505	COG1120	ATPase activity
E1A90_RS02510	COG2819	hydrolase of the alpha beta superfamily
E1A90_RS02530	COG1937	Protein conserved in bacteria
E1A90_RS02535	COG2608	mercury ion transmembrane transporter activity
E1A90_RS02540	COG2217	Heavy metal translocating P-type atpase
E1A90_RS02555	COG2116	formate transmembrane transporter activity
E1A90_RS02560	COG1408	metallophosphoesterase
E1A90_RS02565	COG1473	amidohydrolase
E1A90_RS02580	COG1113	amino acid transport
E1A90_RS02590	COG2322	membrane
E1A90_RS02595	COG1979	alcohol dehydrogenase
E1A90_RS02600	COG1349	DNA-binding transcription factor activity
E1A90_RS02605	COG1105	Belongs to the carbohydrate kinase PfkB family
E1A90_RS02610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A90_RS02610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A90_RS02610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
E1A90_RS02615	COG3584	3D domain protein
E1A90_RS02615	COG1388	LysM domain
E1A90_RS02625	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
E1A90_RS02650	COG2860	membrane
E1A90_RS02655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E1A90_RS02660	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
E1A90_RS02665	COG0789	Transcriptional regulator
E1A90_RS02670	COG0174	glutamine synthetase
E1A90_RS02675	COG3944	biosynthesis protein
E1A90_RS02680	COG0489	protein tyrosine kinase activity
E1A90_RS02685	COG1086	Polysaccharide biosynthesis protein
E1A90_RS02690	COG0438	transferase activity, transferring glycosyl groups
E1A90_RS02695	COG0438	transferase activity, transferring glycosyl groups
E1A90_RS02700	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
E1A90_RS02700	COG0463	Glycosyl transferase, family 2
E1A90_RS02710	COG0438	transferase activity, transferring glycosyl groups
E1A90_RS02735	COG5434	Belongs to the glycosyl hydrolase 28 family
E1A90_RS02735	COG3420	alginic acid biosynthetic process
E1A90_RS02750	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
E1A90_RS02785	COG1132	(ABC) transporter
E1A90_RS02790	COG1695	Transcriptional regulator
E1A90_RS02810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
E1A90_RS02820	COG0737	Belongs to the 5'-nucleotidase family
E1A90_RS02835	COG3639	organic phosphonate transmembrane transporter activity
E1A90_RS02855	COG3763	UPF0154 protein
E1A90_RS02865	COG1132	(ABC) transporter
E1A90_RS02885	COG5632	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS02885	COG3409	Peptidoglycan-binding domain 1 protein
E1A90_RS02895	COG0730	response to heat
E1A90_RS02910	COG1346	cytolysis
E1A90_RS02920	COG0583	DNA-binding transcription factor activity
E1A90_RS02930	COG1131	(ABC) transporter
E1A90_RS02935	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
E1A90_RS02940	COG1473	amidohydrolase
E1A90_RS02955	COG0785	Cytochrome C biogenesis protein
E1A90_RS02960	COG4846	Membrane protein involved in cytochrome C biogenesis
E1A90_RS02990	COG2226	methyltransferase
E1A90_RS03000	COG2986	histidine ammonia-lyase
E1A90_RS03005	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
E1A90_RS03015	COG0010	Belongs to the arginase family
E1A90_RS03020	COG1329	Transcriptional regulator
E1A90_RS03025	COG1902	pentaerythritol trinitrate reductase activity
E1A90_RS03030	COG0069	glutamate synthase activity
E1A90_RS03035	COG0346	lactoylglutathione lyase activity
E1A90_RS03040	COG0400	carboxylic ester hydrolase activity
E1A90_RS03050	COG5002	protein histidine kinase activity
E1A90_RS03100	COG1396	sequence-specific DNA binding
E1A90_RS03115	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS03120	COG1268	BioY protein
E1A90_RS03125	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS03130	COG0183	Belongs to the thiolase family
E1A90_RS03145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E1A90_RS03155	COG2211	Major facilitator Superfamily
E1A90_RS03185	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
E1A90_RS03190	COG1266	CAAX protease self-immunity
E1A90_RS03195	COG2274	protein secretion by the type I secretion system
E1A90_RS03220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS03245	COG0824	Thioesterase
E1A90_RS03250	COG4841	protein insertion into membrane
E1A90_RS03260	COG1328	CTP reductase activity
E1A90_RS03260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E1A90_RS03270	COG0745	RESPONSE REGULATOR receiver
E1A90_RS03275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A90_RS03280	COG1832	CoA-binding protein
E1A90_RS03285	COG0187	DNA topoisomerase II activity
E1A90_RS03290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
E1A90_RS03295	COG0673	inositol 2-dehydrogenase activity
E1A90_RS03315	COG1131	(ABC) transporter
E1A90_RS03325	COG1595	DNA-templated transcription, initiation
E1A90_RS03335	COG1316	TRANSCRIPTIONal
E1A90_RS03350	COG4166	transmembrane transport
E1A90_RS03355	COG2226	methyltransferase
E1A90_RS03385	COG0531	amino acid
E1A90_RS03390	COG3326	Membrane
E1A90_RS03395	COG2962	Rard protein
E1A90_RS03400	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
E1A90_RS03405	COG1657	PFAM Prenyltransferase squalene oxidase
E1A90_RS03415	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS03430	COG4145	pantothenate transmembrane transporter activity
E1A90_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS03475	COG0494	nUDIX hydrolase
E1A90_RS03485	COG0716	FMN binding
E1A90_RS03495	COG1278	Cold shock
E1A90_RS03520	COG2720	vancomycin resistance protein
E1A90_RS03525	COG0765	amino acid transport
E1A90_RS03530	COG1126	abc transporter atp-binding protein
E1A90_RS03535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A90_RS03540	COG2514	catechol 2,3-dioxygenase activity
E1A90_RS03555	COG1285	pathogenesis
E1A90_RS03575	COG0277	FAD linked oxidase domain protein
E1A90_RS03585	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E1A90_RS03590	COG2808	Putative FMN-binding domain
E1A90_RS03595	COG0457	Tetratricopeptide repeat
E1A90_RS03605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
E1A90_RS03610	COG0604	alcohol dehydrogenase
E1A90_RS03615	COG0640	Transcriptional regulator
E1A90_RS03675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E1A90_RS03690	COG3781	membrane
E1A90_RS03720	COG2162	N-hydroxyarylamine O-acetyltransferase activity
E1A90_RS03730	COG1193	negative regulation of DNA recombination
E1A90_RS03750	COG0583	DNA-binding transcription factor activity
E1A90_RS03770	COG3739	integral membrane protein
E1A90_RS03775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS03780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS03785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS03805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E1A90_RS03810	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1A90_RS03840	COG2814	Major facilitator Superfamily
E1A90_RS03850	COG1113	amino acid transport
E1A90_RS03855	COG0604	alcohol dehydrogenase
E1A90_RS03860	COG1695	Transcriptional regulator
E1A90_RS03905	COG2072	flavoprotein involved in K transport
E1A90_RS03945	COG1151	hydroxylamine reductase activity
E1A90_RS03970	COG0814	amino acid
E1A90_RS03990	COG1309	transcriptional regulator
E1A90_RS03995	COG2814	Major facilitator Superfamily
E1A90_RS04005	COG0657	acetylesterase activity
E1A90_RS04030	COG5002	protein histidine kinase activity
E1A90_RS04055	COG0741	lytic transglycosylase activity
E1A90_RS04095	COG1876	peptidase activity
E1A90_RS04110	COG1191	sigma factor activity
E1A90_RS04140	COG1733	regulation of RNA biosynthetic process
E1A90_RS04145	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A90_RS04150	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS04160	COG0384	phenazine biosynthesis protein PhzF
E1A90_RS04175	COG0494	nUDIX hydrolase
E1A90_RS04190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS04200	COG1393	Belongs to the ArsC family
E1A90_RS04220	COG0814	amino acid
E1A90_RS04235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
E1A90_RS04240	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
E1A90_RS04250	COG1070	Carbohydrate kinase
E1A90_RS04255	COG2706	6-phosphogluconolactonase activity
E1A90_RS04260	COG3813	Protein conserved in bacteria
E1A90_RS04265	COG1357	PFAM Pentapeptide repeats (8 copies)
E1A90_RS04275	COG0697	spore germination
E1A90_RS04300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
E1A90_RS04310	COG0789	Transcriptional regulator
E1A90_RS04315	COG1253	flavin adenine dinucleotide binding
E1A90_RS04325	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
E1A90_RS04345	COG0477	Major facilitator Superfamily
E1A90_RS04355	COG0500	methyltransferase
E1A90_RS04360	COG1720	tRNA m6t6A37 methyltransferase activity
E1A90_RS04370	COG2261	transglycosylase associated protein
E1A90_RS04375	COG0628	permease
E1A90_RS04390	COG0110	maltose O-acetyltransferase activity
E1A90_RS04400	COG1940	carbohydrate kinase activity
E1A90_RS04405	COG0346	lactoylglutathione lyase activity
E1A90_RS04430	COG1011	Hydrolase
E1A90_RS04445	COG1595	DNA-templated transcription, initiation
E1A90_RS04475	COG1131	(ABC) transporter
E1A90_RS04485	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS04505	COG1733	regulation of RNA biosynthetic process
E1A90_RS04510	COG0778	Nitroreductase
E1A90_RS04515	COG1785	Belongs to the alkaline phosphatase family
E1A90_RS04535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
E1A90_RS04555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E1A90_RS04560	COG2356	endonuclease I
E1A90_RS04565	COG1288	antiporter activity
E1A90_RS04570	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
E1A90_RS04595	COG1122	ATPase activity
E1A90_RS04635	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A90_RS04645	COG2031	fatty acid transporter
E1A90_RS04660	COG4187	Peptidase family M20/M25/M40
E1A90_RS04725	COG1609	Transcriptional regulator
E1A90_RS04730	COG2814	Major facilitator Superfamily
E1A90_RS04740	COG0673	inositol 2-dehydrogenase activity
E1A90_RS04765	COG0191	fructose-bisphosphate aldolase activity
E1A90_RS04770	COG3718	enzyme involved in inositol metabolism
E1A90_RS04820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
E1A90_RS04825	COG1288	antiporter activity
E1A90_RS04885	COG2814	Major facilitator Superfamily
E1A90_RS04890	COG1846	Transcriptional regulator
E1A90_RS04920	COG2843	Capsule synthesis protein
E1A90_RS04925	COG1876	peptidase activity
E1A90_RS05000	COG2197	response regulator
E1A90_RS05025	COG5444	nuclease activity
E1A90_RS05050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
E1A90_RS05070	COG1619	proteins homologs of microcin C7 resistance protein MccF
E1A90_RS05105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS05115	COG5002	protein histidine kinase activity
E1A90_RS05115	COG3850	Histidine kinase
E1A90_RS05140	COG1136	(ABC) transporter
E1A90_RS05160	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
E1A90_RS05175	COG1690	Belongs to the RtcB family
E1A90_RS05210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A90_RS05230	COG1476	TRANSCRIPTIONal
E1A90_RS05260	COG2515	1-aminocyclopropane-1-carboxylate deaminase
E1A90_RS05290	COG5002	protein histidine kinase activity
E1A90_RS05290	COG3850	Histidine kinase
E1A90_RS05295	COG0745	RESPONSE REGULATOR receiver
E1A90_RS05325	COG2814	Major facilitator Superfamily
E1A90_RS05405	COG0346	lactoylglutathione lyase activity
E1A90_RS05420	COG1522	sequence-specific DNA binding
E1A90_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS05430	COG1309	transcriptional regulator
E1A90_RS05435	COG3320	Male sterility
E1A90_RS05435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E1A90_RS05445	COG0825	malonyl-CoA metabolic process
E1A90_RS05465	COG0640	Transcriptional regulator
E1A90_RS05470	COG0346	lactoylglutathione lyase activity
E1A90_RS05475	COG0798	PFAM Bile acid sodium symporter
E1A90_RS05500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
E1A90_RS05505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E1A90_RS05510	COG1999	signal sequence binding
E1A90_RS05525	COG1121	(ABC) transporter
E1A90_RS05530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
E1A90_RS05535	COG0803	Belongs to the bacterial solute-binding protein 9 family
E1A90_RS05585	COG1575	Belongs to the MenA family. Type 1 subfamily
E1A90_RS05595	COG0745	RESPONSE REGULATOR receiver
E1A90_RS05600	COG5002	protein histidine kinase activity
E1A90_RS05635	COG0730	response to heat
E1A90_RS05650	COG0574	Belongs to the PEP-utilizing enzyme family
E1A90_RS05650	COG3848	Pyruvate phosphate dikinase
E1A90_RS05665	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
E1A90_RS05680	COG3314	Sporulation integral membrane protein YlbJ
E1A90_RS05690	COG0640	Transcriptional regulator
E1A90_RS05715	COG1960	acyl-CoA dehydrogenase activity
E1A90_RS05735	COG1414	Transcriptional regulator
E1A90_RS05740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
E1A90_RS05745	COG1984	allophanate hydrolase subunit 2
E1A90_RS05750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
E1A90_RS05765	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
E1A90_RS05785	COG3104	oligopeptide transport
E1A90_RS05795	COG0768	penicillin binding
E1A90_RS05840	COG0833	amino acid
E1A90_RS05850	COG0730	response to heat
E1A90_RS05875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E1A90_RS05875	COG0456	acetyltransferase
E1A90_RS05905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS05910	COG0697	spore germination
E1A90_RS05925	COG0456	acetyltransferase
E1A90_RS05955	COG3831	ATPase activity
E1A90_RS05955	COG4884	unkown
E1A90_RS05980	COG1846	Transcriptional regulator
E1A90_RS05985	COG0778	Nitroreductase
E1A90_RS06005	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
E1A90_RS06025	COG0753	catalase activity
E1A90_RS06030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
E1A90_RS06050	COG0714	Associated with various cellular activities
E1A90_RS06075	COG0346	lactoylglutathione lyase activity
E1A90_RS06080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS06125	COG3655	Transcriptional regulator
E1A90_RS06140	COG3239	Fatty acid desaturase
E1A90_RS06145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E1A90_RS06150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
E1A90_RS06155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
E1A90_RS06190	COG2329	Antibiotic biosynthesis monooxygenase
E1A90_RS06195	COG0346	lactoylglutathione lyase activity
E1A90_RS06210	COG2226	methyltransferase
E1A90_RS06230	COG2390	Transcriptional regulator
E1A90_RS06250	COG1879	ABC-type sugar transport system periplasmic component
E1A90_RS06255	COG0579	oxidoreductase
E1A90_RS06285	COG0431	NADPH-dependent FMN reductase
E1A90_RS06295	COG0346	lactoylglutathione lyase activity
E1A90_RS06305	COG1388	LysM domain
E1A90_RS06305	COG3584	3D domain protein
E1A90_RS06355	COG2308	Evidence 4 Homologs of previously reported genes of
E1A90_RS06355	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
E1A90_RS06380	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E1A90_RS06380	COG1605	Chorismate mutase
E1A90_RS06395	COG0287	Prephenate dehydrogenase
E1A90_RS06415	COG1309	transcriptional regulator
E1A90_RS06425	COG1033	growth of symbiont in host cell
E1A90_RS06425	COG2409	Drug exporters of the RND superfamily
E1A90_RS06430	COG0488	(ABC) transporter
E1A90_RS06445	COG1368	sulfuric ester hydrolase activity
E1A90_RS06450	COG2814	Major facilitator Superfamily
E1A90_RS06500	COG0697	spore germination
E1A90_RS06515	COG2746	aminoglycoside 3-N-acetyltransferase activity
E1A90_RS06560	COG0628	permease
E1A90_RS06610	COG1131	(ABC) transporter
E1A90_RS06635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
E1A90_RS06640	COG0436	Aminotransferase
E1A90_RS06675	COG2226	methyltransferase
E1A90_RS06690	COG2261	transglycosylase associated protein
E1A90_RS06710	COG0477	Major facilitator Superfamily
E1A90_RS06710	COG2814	Major facilitator Superfamily
E1A90_RS06715	COG4533	DNA binding
E1A90_RS06720	COG0789	Transcriptional regulator
E1A90_RS06725	COG1664	Polymer-forming cytoskeletal
E1A90_RS06735	COG2814	Major facilitator Superfamily
E1A90_RS06750	COG1335	isochorismatase
E1A90_RS06785	COG1307	EDD domain protein, DegV family
E1A90_RS06815	COG0745	RESPONSE REGULATOR receiver
E1A90_RS06820	COG5002	protein histidine kinase activity
E1A90_RS06825	COG2936	dipeptidyl-peptidase activity
E1A90_RS06865	COG0667	Aldo Keto reductase
E1A90_RS06885	COG4948	Mandelate Racemase Muconate Lactonizing
E1A90_RS06895	COG4166	transmembrane transport
E1A90_RS06900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E1A90_RS06915	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS06955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E1A90_RS06960	COG3938	Belongs to the proline racemase family
E1A90_RS06970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
E1A90_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS06985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A90_RS07010	COG3397	chitin binding
E1A90_RS07015	COG1227	inorganic diphosphatase activity
E1A90_RS07025	COG4637	Psort location Cytoplasmic, score
E1A90_RS07045	COG0514	ATP-dependent DNA helicase (RecQ)
E1A90_RS07050	COG2105	PFAM AIG2 family protein
E1A90_RS07110	COG2315	Protein conserved in bacteria
E1A90_RS07115	COG2205	protein histidine kinase activity
E1A90_RS07130	COG1819	glycosyl
E1A90_RS07140	COG3397	chitin binding
E1A90_RS07145	COG2153	protein acetylation
E1A90_RS07150	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
E1A90_RS07175	COG0517	IMP dehydrogenase activity
E1A90_RS07175	COG4175	Glycine betaine
E1A90_RS07180	COG4176	ABC-type proline glycine betaine transport system permease component
E1A90_RS07215	COG0456	acetyltransferase
E1A90_RS07215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E1A90_RS07220	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS07230	COG2223	nitrite transmembrane transporter activity
E1A90_RS07255	COG1959	2 iron, 2 sulfur cluster binding
E1A90_RS07275	COG1349	DNA-binding transcription factor activity
E1A90_RS07305	COG1309	transcriptional regulator
E1A90_RS07310	COG3844	kynureninase activity
E1A90_RS07315	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
E1A90_RS07320	COG3483	tryptophan 2,3-dioxygenase activity
E1A90_RS07350	COG2959	enzyme of heme biosynthesis
E1A90_RS07395	COG0604	alcohol dehydrogenase
E1A90_RS07400	COG3773	Cell wall hydrolase
E1A90_RS07415	COG0745	RESPONSE REGULATOR receiver
E1A90_RS07420	COG2205	protein histidine kinase activity
E1A90_RS07430	COG0667	Aldo Keto reductase
E1A90_RS07435	COG0488	(ABC) transporter
E1A90_RS07450	COG1136	(ABC) transporter
E1A90_RS07475	COG0460	homoserine dehydrogenase
E1A90_RS07480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS07490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
E1A90_RS07500	COG0582	viral genome integration into host DNA
E1A90_RS07515	COG1396	sequence-specific DNA binding
E1A90_RS07520	COG1396	sequence-specific DNA binding
E1A90_RS07545	COG2002	toxin-antitoxin pair type II binding
E1A90_RS07615	COG0582	viral genome integration into host DNA
E1A90_RS07645	COG4626	Terminase
E1A90_RS07645	COG1802	Transcriptional regulator
E1A90_RS07655	COG0740	serine-type endopeptidase activity
E1A90_RS07740	COG1533	DNA photolyase activity
E1A90_RS07755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A90_RS07810	COG2124	cytochrome p450
E1A90_RS07860	COG0561	phosphatase activity
E1A90_RS07865	COG5002	protein histidine kinase activity
E1A90_RS07870	COG0768	penicillin binding
E1A90_RS07885	COG1794	racemase activity, acting on amino acids and derivatives
E1A90_RS07890	COG4720	Psort location CytoplasmicMembrane, score
E1A90_RS07895	COG1122	ATPase activity
E1A90_RS07910	COG2205	protein histidine kinase activity
E1A90_RS07920	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E1A90_RS07925	COG0604	alcohol dehydrogenase
E1A90_RS07930	COG0671	phosphoesterase, PA-phosphatase related
E1A90_RS07935	COG0768	penicillin binding
E1A90_RS07970	COG1132	(ABC) transporter
E1A90_RS07975	COG1132	(ABC) transporter
E1A90_RS07975	COG2375	cellular response to nickel ion
E1A90_RS07990	COG2814	Major facilitator Superfamily
E1A90_RS08015	COG0584	glycerophosphoryl diester phosphodiesterase
E1A90_RS08030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS08035	COG0697	spore germination
E1A90_RS08075	COG2223	nitrite transmembrane transporter activity
E1A90_RS08085	COG2816	NAD+ diphosphatase activity
E1A90_RS08090	COG0592	DNA-directed DNA polymerase activity
E1A90_RS08125	COG3878	Protein conserved in bacteria
E1A90_RS08150	COG4667	esterase of the alpha-beta hydrolase superfamily
E1A90_RS08165	COG2318	DinB family
E1A90_RS08190	COG0322	excinuclease ABC activity
E1A90_RS08210	COG3961	Belongs to the TPP enzyme family
E1A90_RS08215	COG1132	(ABC) transporter
E1A90_RS08225	COG1183	phosphatidylcholine synthase activity
E1A90_RS08230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E1A90_RS08255	COG1011	Hydrolase
E1A90_RS08260	COG0745	RESPONSE REGULATOR receiver
E1A90_RS08290	COG1136	(ABC) transporter
E1A90_RS08325	COG1523	belongs to the glycosyl hydrolase 13 family
E1A90_RS08330	COG3227	Zinc metalloprotease (Elastase)
E1A90_RS08335	COG0737	Belongs to the 5'-nucleotidase family
E1A90_RS08345	COG0201	protein transport
E1A90_RS08350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A90_RS08355	COG0697	spore germination
E1A90_RS08420	COG0697	spore germination
E1A90_RS08450	COG1309	transcriptional regulator
E1A90_RS08475	COG1733	regulation of RNA biosynthetic process
E1A90_RS08480	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS08535	COG2207	Transcriptional regulator
E1A90_RS08555	COG2801	Transposase and inactivated derivatives
E1A90_RS08580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E1A90_RS08610	COG2318	DinB family
E1A90_RS08655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1A90_RS08660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
E1A90_RS08665	COG1024	Enoyl-CoA hydratase
E1A90_RS08675	COG0511	ligase activity, forming carbon-carbon bonds
E1A90_RS08680	COG0439	Biotin carboxylase
E1A90_RS08685	COG1960	acyl-CoA dehydrogenase activity
E1A90_RS08705	COG1131	(ABC) transporter
E1A90_RS08725	COG0823	Involved in the tonB-independent uptake of proteins
E1A90_RS08730	COG3397	chitin binding
E1A90_RS08760	COG0697	spore germination
E1A90_RS08775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS08775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A90_RS08780	COG1252	NADH dehydrogenase
E1A90_RS08825	COG0768	penicillin binding
E1A90_RS08840	COG1595	DNA-templated transcription, initiation
E1A90_RS08850	COG0577	efflux transmembrane transporter activity
E1A90_RS08855	COG1136	(ABC) transporter
E1A90_RS08860	COG2205	protein histidine kinase activity
E1A90_RS08865	COG0745	RESPONSE REGULATOR receiver
E1A90_RS08895	COG1686	Belongs to the peptidase S11 family
E1A90_RS08925	COG1136	(ABC) transporter
E1A90_RS08945	COG0577	efflux transmembrane transporter activity
E1A90_RS08950	COG1136	(ABC) transporter
E1A90_RS08955	COG2205	protein histidine kinase activity
E1A90_RS08960	COG0745	RESPONSE REGULATOR receiver
E1A90_RS08965	COG0110	maltose O-acetyltransferase activity
E1A90_RS08970	COG2195	Cleaves the N-terminal amino acid of tripeptides
E1A90_RS08990	COG0588	phosphoglycerate mutase activity
E1A90_RS09010	COG0500	methyltransferase
E1A90_RS09010	COG3615	Tellurite resistance protein tehB
E1A90_RS09015	COG1136	(ABC) transporter
E1A90_RS09030	COG1309	transcriptional regulator
E1A90_RS09095	COG2971	BadF BadG BcrA BcrD
E1A90_RS09100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
E1A90_RS09120	COG1649	PFAM Uncharacterised BCR, COG1649
E1A90_RS09140	COG1595	DNA-templated transcription, initiation
E1A90_RS09145	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
E1A90_RS09185	COG1396	sequence-specific DNA binding
E1A90_RS09205	COG1132	(ABC) transporter
E1A90_RS09210	COG1132	(ABC) transporter
E1A90_RS09230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS09235	COG0583	DNA-binding transcription factor activity
E1A90_RS09280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E1A90_RS09285	COG0583	DNA-binding transcription factor activity
E1A90_RS09315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS09325	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E1A90_RS09330	COG0596	Alpha beta hydrolase
E1A90_RS09370	COG1247	-acetyltransferase
E1A90_RS09400	COG1309	transcriptional regulator
E1A90_RS09405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS09420	COG1846	Transcriptional regulator
E1A90_RS09440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
E1A90_RS09475	COG1253	flavin adenine dinucleotide binding
E1A90_RS09500	COG0028	Belongs to the TPP enzyme family
E1A90_RS09525	COG1136	(ABC) transporter
E1A90_RS09535	COG3655	Transcriptional regulator
E1A90_RS09540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E1A90_RS09545	COG1187	pseudouridine synthase activity
E1A90_RS09560	COG2329	Antibiotic biosynthesis monooxygenase
E1A90_RS09570	COG2318	DinB family
E1A90_RS09580	COG0776	regulation of translation
E1A90_RS09595	COG2814	Major facilitator Superfamily
E1A90_RS09605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E1A90_RS09610	COG3433	isochorismatase activity
E1A90_RS09610	COG1535	isochorismatase
E1A90_RS09615	COG1021	2,3-dihydroxybenzoate-AMP ligase
E1A90_RS09620	COG1169	isochorismate synthase
E1A90_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS09630	COG2223	nitrite transmembrane transporter activity
E1A90_RS09650	COG0420	3'-5' exonuclease activity
E1A90_RS09670	COG1280	lysine exporter protein (LysE YggA)
E1A90_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS09680	COG2084	Dehydrogenase
E1A90_RS09690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
E1A90_RS09695	COG2079	MmgE PrpD family protein
E1A90_RS09700	COG0372	Belongs to the citrate synthase family
E1A90_RS09710	COG2814	Major facilitator Superfamily
E1A90_RS09720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A90_RS09720	COG4499	WXG100 protein secretion system (Wss), protein YukC
E1A90_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS09775	COG2140	Oxalate decarboxylase
E1A90_RS09810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E1A90_RS09890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS09895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E1A90_RS09905	COG4991	sh3 domain protein
E1A90_RS09905	COG3064	Membrane
E1A90_RS09905	COG0515	serine threonine protein kinase
E1A90_RS09930	COG4479	Belongs to the UPF0346 family
E1A90_RS09940	COG1509	lysine 2,3-aminomutase activity
E1A90_RS09945	COG3829	transcription factor binding
E1A90_RS09950	COG0456	acetyltransferase
E1A90_RS09955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E1A90_RS09960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
E1A90_RS09965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
E1A90_RS09970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E1A90_RS09985	COG5506	Protein of unknown function (DUF1694)
E1A90_RS09990	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS10030	COG1174	glycine betaine transport
E1A90_RS10050	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
E1A90_RS10060	COG1070	Carbohydrate kinase
E1A90_RS10075	COG1064	alcohol dehydrogenase
E1A90_RS10080	COG1737	Transcriptional regulator
E1A90_RS10085	COG2197	response regulator
E1A90_RS10090	COG2203	Gaf domain
E1A90_RS10090	COG4585	Histidine kinase
E1A90_RS10100	COG1051	belongs to the nudix hydrolase family
E1A90_RS10105	COG1335	isochorismatase
E1A90_RS10130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS10135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS10140	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS10155	COG0367	asparagine synthase
E1A90_RS10160	COG0071	Belongs to the small heat shock protein (HSP20) family
E1A90_RS10165	COG1999	signal sequence binding
E1A90_RS10170	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E1A90_RS10185	COG0805	protein transport
E1A90_RS10190	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
E1A90_RS10195	COG1272	protein, Hemolysin III
E1A90_RS10200	COG0204	Acyl-transferase
E1A90_RS10245	COG0546	phosphoglycolate phosphatase activity
E1A90_RS10255	COG4473	ABC transporter
E1A90_RS10260	COG1131	(ABC) transporter
E1A90_RS10265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
E1A90_RS10270	COG0456	acetyltransferase
E1A90_RS10280	COG1794	racemase activity, acting on amino acids and derivatives
E1A90_RS10290	COG2610	gluconate transmembrane transporter activity
E1A90_RS10320	COG0733	neurotransmitter:sodium symporter activity
E1A90_RS10400	COG0017	Asparaginyl-tRNA synthetase
E1A90_RS10440	COG2226	methyltransferase
E1A90_RS10455	COG0018	arginyl-trna synthetase
E1A90_RS10460	COG2521	methyltransferase
E1A90_RS10460	COG2136	Putative SAM-dependent methyltransferase
E1A90_RS10475	COG1413	lyase activity
E1A90_RS10500	COG1418	mRNA catabolic process
E1A90_RS10510	COG2359	stage V sporulation protein S
E1A90_RS10540	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
E1A90_RS10545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E1A90_RS10550	COG2146	nitrite reductase [NAD(P)H] activity
E1A90_RS10555	COG1587	Uroporphyrinogen-III synthase
E1A90_RS10555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
E1A90_RS10565	COG1648	precorrin-2 dehydrogenase activity
E1A90_RS10595	COG0314	molybdopterin synthase activity
E1A90_RS10600	COG0303	'Molybdopterin
E1A90_RS10605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A90_RS10610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E1A90_RS10620	COG2181	nitrate reductase activity
E1A90_RS10625	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
E1A90_RS10630	COG1140	nitrate reductase beta subunit
E1A90_RS10635	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
E1A90_RS10650	COG0714	Associated with various cellular activities
E1A90_RS10655	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
E1A90_RS10670	COG0386	Belongs to the glutathione peroxidase family
E1A90_RS10680	COG0426	domain, Protein
E1A90_RS10680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E1A90_RS10705	COG1595	DNA-templated transcription, initiation
E1A90_RS10710	COG0604	alcohol dehydrogenase
E1A90_RS10740	COG2226	methyltransferase
E1A90_RS10765	COG3874	Sporulation protein YtfJ
E1A90_RS10835	COG0456	acetyltransferase
E1A90_RS10865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS10870	COG1819	glycosyl
E1A90_RS10905	COG1846	Transcriptional regulator
E1A90_RS10910	COG0561	phosphatase activity
E1A90_RS10920	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS10935	COG2211	Major facilitator Superfamily
E1A90_RS10945	COG0494	nUDIX hydrolase
E1A90_RS10950	COG1876	peptidase activity
E1A90_RS10965	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS10985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E1A90_RS10990	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS11015	COG1253	flavin adenine dinucleotide binding
E1A90_RS11020	COG2839	Protein conserved in bacteria
E1A90_RS11025	COG0702	epimerase
E1A90_RS11045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A90_RS11055	COG1607	acyl-coa hydrolase
E1A90_RS11060	COG3689	TIGRFAM TIGR03943 family protein
E1A90_RS11065	COG0701	Predicted permease
E1A90_RS11080	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS11085	COG1051	belongs to the nudix hydrolase family
E1A90_RS11100	COG0406	alpha-ribazole phosphatase activity
E1A90_RS11110	COG0346	lactoylglutathione lyase activity
E1A90_RS11125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
E1A90_RS11130	COG1902	pentaerythritol trinitrate reductase activity
E1A90_RS11145	COG0803	Belongs to the bacterial solute-binding protein 9 family
E1A90_RS11150	COG0456	acetyltransferase
E1A90_RS11155	COG0523	cobalamin synthesis protein
E1A90_RS11160	COG4989	oxidoreductase activity
E1A90_RS11165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS11180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1A90_RS11195	COG0783	Belongs to the Dps family
E1A90_RS11245	COG2814	Major facilitator Superfamily
E1A90_RS11255	COG0640	Transcriptional regulator
E1A90_RS11260	COG1404	Belongs to the peptidase S8 family
E1A90_RS11265	COG2002	toxin-antitoxin pair type II binding
E1A90_RS11270	COG0577	efflux transmembrane transporter activity
E1A90_RS11275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
E1A90_RS11305	COG1752	Esterase of the alpha-beta hydrolase superfamily
E1A90_RS11315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS11320	COG1279	arginine transmembrane transporter activity
E1A90_RS11325	COG2814	Major facilitator Superfamily
E1A90_RS11335	COG1082	Xylose isomerase domain protein TIM barrel
E1A90_RS11345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E1A90_RS11365	COG1247	-acetyltransferase
E1A90_RS11370	COG1285	pathogenesis
E1A90_RS11385	COG1316	TRANSCRIPTIONal
E1A90_RS11400	COG0083	homoserine kinase activity
E1A90_RS11410	COG0460	homoserine dehydrogenase
E1A90_RS11440	COG4122	O-methyltransferase activity
E1A90_RS11445	COG0300	oxidoreductase activity
E1A90_RS11450	COG5002	protein histidine kinase activity
E1A90_RS11455	COG0745	RESPONSE REGULATOR receiver
E1A90_RS11470	COG0791	NLP P60 protein
E1A90_RS11470	COG1388	LysM domain
E1A90_RS11485	COG1686	Belongs to the peptidase S11 family
E1A90_RS11515	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
E1A90_RS11520	COG4988	ABC transporter
E1A90_RS11525	COG1294	oxidase, subunit
E1A90_RS11540	COG0346	lactoylglutathione lyase activity
E1A90_RS11555	COG1942	4-Oxalocrotonate Tautomerase
E1A90_RS11565	COG0583	DNA-binding transcription factor activity
E1A90_RS11585	COG0411	ABC transporter
E1A90_RS11595	COG0523	cobalamin synthesis protein
E1A90_RS11615	COG0628	permease
E1A90_RS11635	COG0778	Nitroreductase
E1A90_RS11640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
E1A90_RS11645	COG1959	2 iron, 2 sulfur cluster binding
E1A90_RS11650	COG0583	DNA-binding transcription factor activity
E1A90_RS11655	COG0697	spore germination
E1A90_RS11725	COG1834	amidinotransferase
E1A90_RS11735	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS11755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E1A90_RS11770	COG2132	Multicopper oxidase
E1A90_RS11775	COG0006	proline dipeptidase activity
E1A90_RS11795	COG0583	DNA-binding transcription factor activity
E1A90_RS11815	COG4846	Membrane protein involved in cytochrome C biogenesis
E1A90_RS11830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
E1A90_RS11835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A90_RS11840	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
E1A90_RS11850	COG2390	Transcriptional regulator
E1A90_RS11855	COG4257	antibiotic catabolic process
E1A90_RS11870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
E1A90_RS11885	COG1280	lysine exporter protein (LysE YggA)
E1A90_RS11905	COG0531	amino acid
E1A90_RS11910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E1A90_RS11920	COG1054	Belongs to the UPF0176 family
E1A90_RS11925	COG1914	H( )-stimulated, divalent metal cation uptake system
E1A90_RS11945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS11970	COG4166	transmembrane transport
E1A90_RS12030	COG3384	dioxygenase
E1A90_RS12035	COG2814	Major facilitator Superfamily
E1A90_RS12055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
E1A90_RS12075	COG0028	Belongs to the TPP enzyme family
E1A90_RS12080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS12090	COG0745	RESPONSE REGULATOR receiver
E1A90_RS12095	COG5002	protein histidine kinase activity
E1A90_RS12110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E1A90_RS12115	COG0450	alkyl hydroperoxide reductase
E1A90_RS12120	COG0833	amino acid
E1A90_RS12135	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A90_RS12145	COG0110	maltose O-acetyltransferase activity
E1A90_RS12150	COG1733	regulation of RNA biosynthetic process
E1A90_RS12165	COG2323	membrane
E1A90_RS12170	COG5566	PFAM Mor transcription activator
E1A90_RS12180	COG0733	neurotransmitter:sodium symporter activity
E1A90_RS12185	COG2244	polysaccharide biosynthetic process
E1A90_RS12195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E1A90_RS12205	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
E1A90_RS12225	COG0477	Major facilitator Superfamily
E1A90_RS12255	COG2814	Major facilitator Superfamily
E1A90_RS12305	COG2502	aspartate--ammonia ligase
E1A90_RS12320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E1A90_RS12330	COG1846	Transcriptional regulator
E1A90_RS12335	COG0784	Response regulator, receiver
E1A90_RS12340	COG4191	Histidine kinase
E1A90_RS12345	COG0281	malic enzyme
E1A90_RS12350	COG1027	Aspartate ammonia-lyase
E1A90_RS12360	COG0528	UMP kinase activity
E1A90_RS12365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A90_RS12385	COG1131	(ABC) transporter
E1A90_RS12430	COG2733	membrane
E1A90_RS12435	COG3048	D-serine ammonia-lyase activity
E1A90_RS12450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS12455	COG0785	Cytochrome C biogenesis protein
E1A90_RS12475	COG3340	Belongs to the peptidase S51 family
E1A90_RS12480	COG0534	Mate efflux family protein
E1A90_RS12510	COG1757	Na H antiporter
E1A90_RS12515	COG0438	transferase activity, transferring glycosyl groups
E1A90_RS12515	COG1216	Glycosyl transferase, family 2
E1A90_RS12520	COG0697	spore germination
E1A90_RS12525	COG1802	Transcriptional regulator
E1A90_RS12555	COG0367	asparagine synthase
E1A90_RS12585	COG0406	alpha-ribazole phosphatase activity
E1A90_RS12650	COG0583	DNA-binding transcription factor activity
E1A90_RS12660	COG2814	Major facilitator Superfamily
E1A90_RS12675	COG2329	Antibiotic biosynthesis monooxygenase
E1A90_RS12680	COG0412	Dienelactone hydrolase
E1A90_RS12710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1A90_RS12715	COG4786	Flagellar basal body rod
E1A90_RS12725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E1A90_RS12730	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
E1A90_RS12740	COG1987	bacterial-type flagellum assembly
E1A90_RS12745	COG1338	Plays a role in the flagellum-specific transport system
E1A90_RS12755	COG1776	CheC inhibitor of MCP methylation
E1A90_RS12755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A90_RS12760	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A90_RS12770	COG0741	lytic transglycosylase activity
E1A90_RS12775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E1A90_RS12785	COG0489	protein tyrosine kinase activity
E1A90_RS12795	COG0314	molybdopterin synthase activity
E1A90_RS12800	COG0303	'Molybdopterin
E1A90_RS12805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A90_RS12810	COG2116	formate transmembrane transporter activity
E1A90_RS12820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E1A90_RS12825	COG5609	conserved protein (DUF2294)
E1A90_RS12830	COG2427	Protein of unknown function (DUF1641)
E1A90_RS12835	COG3383	formate dehydrogenase (NAD+) activity
E1A90_RS12870	COG0835	chemotaxis
E1A90_RS12870	COG0784	Response regulator, receiver
E1A90_RS12885	COG1749	Flagellar hook protein flgE
E1A90_RS12915	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A90_RS12920	COG1766	The M ring may be actively involved in energy transduction
E1A90_RS12930	COG1558	bacterial-type flagellum-dependent cell motility
E1A90_RS12935	COG1815	bacterial-type flagellum-dependent cell motility
E1A90_RS12960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
E1A90_RS12965	COG1256	bacterial-type flagellum assembly
E1A90_RS12985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E1A90_RS13000	COG1776	CheC inhibitor of MCP methylation
E1A90_RS13000	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
E1A90_RS13010	COG2201	protein-glutamate methylesterase activity
E1A90_RS13015	COG1360	Flagellar Motor Protein
E1A90_RS13020	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E1A90_RS13030	COG1923	regulation of RNA biosynthetic process
E1A90_RS13050	COG2814	Major facilitator Superfamily
E1A90_RS13075	COG1434	Gram-negative-bacterium-type cell wall biogenesis
E1A90_RS13080	COG2323	membrane
E1A90_RS13090	COG0789	Transcriptional regulator
E1A90_RS13090	COG4978	Transcriptional regulator
E1A90_RS13095	COG0475	glutathione-regulated potassium exporter activity
E1A90_RS13110	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1A90_RS13130	COG1280	lysine exporter protein (LysE YggA)
E1A90_RS13135	COG3403	YqcI/YcgG family
E1A90_RS13190	COG0454	-acetyltransferase
E1A90_RS13205	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1A90_RS13245	COG2897	thiosulfate sulfurtransferase activity
E1A90_RS13255	COG0456	acetyltransferase
E1A90_RS13275	COG2311	Membrane
E1A90_RS13280	COG2233	PERMEase
E1A90_RS13285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E1A90_RS13290	COG0024	Methionine aminopeptidase
E1A90_RS13300	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
E1A90_RS13305	COG1199	ATP-dependent helicase activity
E1A90_RS13315	COG0116	Belongs to the methyltransferase superfamily
E1A90_RS13325	COG3599	regulation of cell shape
E1A90_RS13330	COG4474	Belongs to the UPF0398 family
E1A90_RS13365	COG3331	DNA recombination
E1A90_RS13380	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
E1A90_RS13385	COG3935	DnaD domain protein
E1A90_RS13405	COG1199	ATP-dependent helicase activity
E1A90_RS13405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
E1A90_RS13415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
E1A90_RS13420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
E1A90_RS13430	COG0617	tRNA 3'-terminal CCA addition
E1A90_RS13435	COG0438	transferase activity, transferring glycosyl groups
E1A90_RS13440	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1A90_RS13445	COG1803	Methylglyoxal synthase
E1A90_RS13450	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
E1A90_RS13455	COG1694	Mazg nucleotide pyrophosphohydrolase
E1A90_RS13460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS13470	COG2738	Putative neutral zinc metallopeptidase
E1A90_RS13485	COG4347	Protein of unknown function (DUF1405)
E1A90_RS13500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
E1A90_RS13515	COG5582	Belongs to the UPF0302 family
E1A90_RS13520	COG0457	Tetratricopeptide repeat
E1A90_RS13525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
E1A90_RS13535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
E1A90_RS13550	COG0142	geranyltranstransferase activity
E1A90_RS13555	COG2226	methyltransferase
E1A90_RS13560	COG0142	geranyltranstransferase activity
E1A90_RS13565	COG0302	gtp cyclohydrolase
E1A90_RS13575	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E1A90_RS13595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
E1A90_RS13600	COG1160	GTP binding
E1A90_RS13640	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
E1A90_RS13645	COG0252	asparaginase activity
E1A90_RS13650	COG0492	ferredoxin-NADP+ reductase activity
E1A90_RS13670	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
E1A90_RS13695	COG1266	CAAX protease self-immunity
E1A90_RS13705	COG4955	Helix-turn-helix domain
E1A90_RS13715	COG1141	Ferredoxin
E1A90_RS13720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
E1A90_RS13730	COG4942	peptidase
E1A90_RS13745	COG0745	RESPONSE REGULATOR receiver
E1A90_RS13750	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1A90_RS13755	COG1333	cytochrome c biogenesis protein
E1A90_RS13765	COG1187	pseudouridine synthase activity
E1A90_RS13770	COG0700	Nucleoside recognition
E1A90_RS13775	COG2715	membrane protein required for spore maturation
E1A90_RS13780	COG1686	Belongs to the peptidase S11 family
E1A90_RS13815	COG5002	protein histidine kinase activity
E1A90_RS13820	COG0582	viral genome integration into host DNA
E1A90_RS13830	COG1801	Protein of unknown function DUF72
E1A90_RS13835	COG3852	Histidine kinase
E1A90_RS13850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A90_RS13855	COG1392	Phosphate transport regulator
E1A90_RS13860	COG0306	phosphate transporter
E1A90_RS13865	COG0730	response to heat
E1A90_RS13920	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS13930	COG2197	response regulator
E1A90_RS13940	COG4758	membrane
E1A90_RS13955	COG1757	Na H antiporter
E1A90_RS13975	COG0733	neurotransmitter:sodium symporter activity
E1A90_RS14005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
E1A90_RS14010	COG0529	Catalyzes the synthesis of activated sulfate
E1A90_RS14015	COG2046	Belongs to the sulfate adenylyltransferase family
E1A90_RS14020	COG0175	sulfate reduction
E1A90_RS14030	COG0019	diaminopimelate decarboxylase activity
E1A90_RS14040	COG1368	sulfuric ester hydrolase activity
E1A90_RS14045	COG1183	phosphatidylcholine synthase activity
E1A90_RS14060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E1A90_RS14065	COG0140	phosphoribosyl-ATP diphosphatase activity
E1A90_RS14075	COG0107	imidazoleglycerol-phosphate synthase activity
E1A90_RS14080	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
E1A90_RS14085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
E1A90_RS14100	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
E1A90_RS14105	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
E1A90_RS14115	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
E1A90_RS14125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
E1A90_RS14135	COG0440	acetolactate synthase activity
E1A90_RS14140	COG0028	Belongs to the TPP enzyme family
E1A90_RS14145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS14170	COG3874	Sporulation protein YtfJ
E1A90_RS14180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1A90_RS14185	COG1301	dicarboxylic acid transport
E1A90_RS14195	COG1846	Transcriptional regulator
E1A90_RS14220	COG0534	Mate efflux family protein
E1A90_RS14245	COG0716	FMN binding
E1A90_RS14260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
E1A90_RS14265	COG1696	Membrane protein involved in D-alanine export
E1A90_RS14270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E1A90_RS14275	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
E1A90_RS14280	COG2070	2-Nitropropane dioxygenase
E1A90_RS14285	COG1619	proteins homologs of microcin C7 resistance protein MccF
E1A90_RS14295	COG1335	isochorismatase
E1A90_RS14305	COG1522	sequence-specific DNA binding
E1A90_RS14315	COG1266	CAAX protease self-immunity
E1A90_RS14320	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
E1A90_RS14325	COG1131	(ABC) transporter
E1A90_RS14340	COG1725	Transcriptional regulator
E1A90_RS14350	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS14355	COG3829	transcription factor binding
E1A90_RS14355	COG3290	protein histidine kinase activity
E1A90_RS14370	COG0531	amino acid
E1A90_RS14375	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
E1A90_RS14390	COG1780	Probably involved in ribonucleotide reductase function
E1A90_RS14410	COG0456	acetyltransferase
E1A90_RS14420	COG4873	Protein conserved in bacteria
E1A90_RS14425	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
E1A90_RS14435	COG0720	synthase
E1A90_RS14440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
E1A90_RS14445	COG5002	protein histidine kinase activity
E1A90_RS14460	COG1846	Transcriptional regulator
E1A90_RS14485	COG0235	Class ii aldolase
E1A90_RS14505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
E1A90_RS14510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A90_RS14525	COG1840	ABC-type Fe3 transport system, periplasmic component
E1A90_RS14540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1A90_RS14550	COG3243	poly(R)-hydroxyalkanoic acid synthase
E1A90_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS14585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
E1A90_RS14595	COG2116	formate transmembrane transporter activity
E1A90_RS14605	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
E1A90_RS14610	COG1556	Lactate utilization protein
E1A90_RS14615	COG1139	Iron-sulfur cluster binding protein
E1A90_RS14620	COG0247	lactate metabolic process
E1A90_RS14625	COG2186	Transcriptional regulator
E1A90_RS14635	COG0745	RESPONSE REGULATOR receiver
E1A90_RS14645	COG3835	regulator
E1A90_RS14650	COG0277	FAD linked oxidase domain protein
E1A90_RS14655	COG0247	lactate metabolic process
E1A90_RS14660	COG2340	Cysteine-rich secretory protein family
E1A90_RS14670	COG0564	pseudouridine synthase activity
E1A90_RS14680	COG2409	Drug exporters of the RND superfamily
E1A90_RS14690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
E1A90_RS14695	COG1177	transmembrane transport
E1A90_RS14700	COG1176	ABC-type spermidine putrescine transport system, permease component I
E1A90_RS14710	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS14745	COG0681	Belongs to the peptidase S26 family
E1A90_RS14750	COG1686	Belongs to the peptidase S11 family
E1A90_RS14780	COG1668	transmembrane transport
E1A90_RS14785	COG4152	abc transporter atp-binding protein
E1A90_RS14815	COG0567	Dehydrogenase, E1 component
E1A90_RS14820	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1A90_RS14875	COG5634	Uncharacterized conserved protein (DUF2278)
E1A90_RS14880	COG1620	l-lactate permease
E1A90_RS14890	COG0159	tryptophan synthase activity
E1A90_RS14895	COG0133	tryptophan synthase activity
E1A90_RS14900	COG0135	phosphoribosylanthranilate isomerase activity
E1A90_RS14905	COG0134	indole-3-glycerol-phosphate synthase activity
E1A90_RS14910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E1A90_RS14915	COG0512	Glutamine amidotransferase of anthranilate synthase
E1A90_RS14915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
E1A90_RS14930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1A90_RS14935	COG5492	domain, Protein
E1A90_RS14960	COG2382	esterase
E1A90_RS14965	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
E1A90_RS14970	COG2153	protein acetylation
E1A90_RS15015	COG1091	dTDP-4-dehydrorhamnose reductase activity
E1A90_RS15030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
E1A90_RS15050	COG0463	Glycosyl transferase, family 2
E1A90_RS15050	COG0457	Tetratricopeptide repeat
E1A90_RS15070	COG1216	Glycosyl transferase, family 2
E1A90_RS15080	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E1A90_RS15095	COG0564	pseudouridine synthase activity
E1A90_RS15115	COG4116	CYTH
E1A90_RS15120	COG2346	COG2346, Truncated hemoglobins
E1A90_RS15130	COG1164	Oligoendopeptidase f
E1A90_RS15140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A90_RS15145	COG4862	establishment of competence for transformation
E1A90_RS15150	COG0861	Integral membrane protein TerC family
E1A90_RS15165	COG4166	transmembrane transport
E1A90_RS15170	COG0534	Mate efflux family protein
E1A90_RS15175	COG4608	Belongs to the ABC transporter superfamily
E1A90_RS15180	COG0444	Belongs to the ABC transporter superfamily
E1A90_RS15190	COG0601	transmembrane transport
E1A90_RS15195	COG4166	transmembrane transport
E1A90_RS15210	COG0180	Tryptophanyl-tRNA synthetase
E1A90_RS15220	COG5504	Zn-dependent protease
E1A90_RS15225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
E1A90_RS15230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E1A90_RS15245	COG2267	carboxylic ester hydrolase activity
E1A90_RS15265	COG0561	phosphatase activity
E1A90_RS15280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS15330	COG3209	COG3209 Rhs family protein
E1A90_RS15335	COG2996	Protein conserved in bacteria
E1A90_RS15340	COG1666	GTP binding
E1A90_RS15355	COG0004	ammonium transporteR
E1A90_RS15360	COG0753	catalase activity
E1A90_RS15370	COG0367	asparagine synthase
E1A90_RS15395	COG0179	Fumarylacetoacetate (FAA) hydrolase
E1A90_RS15445	COG1074	ATP-dependent DNA helicase activity
E1A90_RS15450	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
E1A90_RS15460	COG0398	Pfam SNARE associated Golgi protein
E1A90_RS15470	COG4903	ComK protein
E1A90_RS15485	COG1278	Cold shock
E1A90_RS15495	COG2224	Isocitrate lyase
E1A90_RS15500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
E1A90_RS15515	COG0697	spore germination
E1A90_RS15520	COG0840	transmembrane signaling receptor activity
E1A90_RS15525	COG0501	Belongs to the peptidase M48B family
E1A90_RS15545	COG0745	RESPONSE REGULATOR receiver
E1A90_RS15550	COG2205	protein histidine kinase activity
E1A90_RS15555	COG2207	Transcriptional regulator
E1A90_RS15555	COG3708	Transcriptional regulator
E1A90_RS15565	COG1595	DNA-templated transcription, initiation
E1A90_RS15580	COG1078	dGTPase activity
E1A90_RS15680	COG4208	sulfate ABC transporter
E1A90_RS15690	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
E1A90_RS15700	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS15710	COG0095	Lipoate-protein ligase
E1A90_RS15715	COG1234	tRNA 3'-trailer cleavage
E1A90_RS15760	COG1511	domain protein
E1A90_RS15765	COG1309	transcriptional regulator
E1A90_RS15790	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
E1A90_RS15795	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
E1A90_RS15800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
E1A90_RS15805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A90_RS15810	COG2329	Antibiotic biosynthesis monooxygenase
E1A90_RS15815	COG3428	Bacterial PH domain
E1A90_RS15820	COG3402	PFAM membrane-flanked domain
E1A90_RS15860	COG3428	Bacterial PH domain
E1A90_RS15865	COG3402	PFAM membrane-flanked domain
E1A90_RS15880	COG1556	Lactate utilization protein
E1A90_RS15885	COG1139	Iron-sulfur cluster binding protein
E1A90_RS15890	COG0247	lactate metabolic process
E1A90_RS15900	COG4473	ABC transporter
E1A90_RS15905	COG1131	(ABC) transporter
E1A90_RS15910	COG0537	adenosine 5'-monophosphoramidase activity
E1A90_RS15935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
E1A90_RS15940	COG3973	AAA domain
E1A90_RS15955	COG1595	DNA-templated transcription, initiation
E1A90_RS15970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
E1A90_RS15975	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
E1A90_RS15980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
E1A90_RS15985	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E1A90_RS15990	COG3620	sequence-specific DNA binding
E1A90_RS16000	COG2267	carboxylic ester hydrolase activity
E1A90_RS16015	COG0346	lactoylglutathione lyase activity
E1A90_RS16020	COG0346	lactoylglutathione lyase activity
E1A90_RS16040	COG0714	Associated with various cellular activities
E1A90_RS16045	COG3481	metal-dependent phosphohydrolase, HD sub domain
E1A90_RS16050	COG4717	serine-type aminopeptidase activity
E1A90_RS16055	COG0420	3'-5' exonuclease activity
E1A90_RS16085	COG2197	response regulator
E1A90_RS16090	COG4585	Histidine kinase
E1A90_RS16095	COG2186	Transcriptional regulator
E1A90_RS16100	COG2807	transmembrane transport
E1A90_RS16130	COG5002	protein histidine kinase activity
E1A90_RS16130	COG2205	protein histidine kinase activity
E1A90_RS16130	COG0784	Response regulator, receiver
E1A90_RS16135	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
E1A90_RS16140	COG2208	phosphoserine phosphatase activity
E1A90_RS16150	COG1191	sigma factor activity
E1A90_RS16155	COG2172	sigma factor antagonist activity
E1A90_RS16175	COG3237	CsbD-like
E1A90_RS16220	COG1136	(ABC) transporter
E1A90_RS16275	COG1136	(ABC) transporter
E1A90_RS16285	COG2205	protein histidine kinase activity
E1A90_RS16315	COG2720	vancomycin resistance protein
E1A90_RS16330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
E1A90_RS16375	COG2376	Dihydroxyacetone kinase
E1A90_RS16400	COG0640	Transcriptional regulator
E1A90_RS16405	COG2814	Major facilitator Superfamily
E1A90_RS16410	COG2732	(Barnase) inhibitor
E1A90_RS16470	COG1183	phosphatidylcholine synthase activity
E1A90_RS16520	COG0477	Major facilitator Superfamily
E1A90_RS16545	COG0305	Participates in initiation and elongation during chromosome replication
E1A90_RS16615	COG1074	ATP-dependent DNA helicase activity
E1A90_RS16630	COG3181	Tripartite tricarboxylate transporter family receptor
E1A90_RS16635	COG4565	transcriptional regulatory protein
E1A90_RS16640	COG3290	protein histidine kinase activity
E1A90_RS16645	COG0477	Major facilitator Superfamily
E1A90_RS16690	COG4608	Belongs to the ABC transporter superfamily
E1A90_RS16695	COG0444	Belongs to the ABC transporter superfamily
E1A90_RS16700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A90_RS16705	COG0601	transmembrane transport
E1A90_RS16725	COG3829	transcription factor binding
E1A90_RS16725	COG3290	protein histidine kinase activity
E1A90_RS16730	COG2226	methyltransferase
E1A90_RS16735	COG0579	oxidoreductase
E1A90_RS16755	COG2318	DinB family
E1A90_RS16775	COG1363	Peptidase, m42
E1A90_RS16795	COG1024	Enoyl-CoA hydratase
E1A90_RS16815	COG2244	polysaccharide biosynthetic process
E1A90_RS16820	COG0659	secondary active sulfate transmembrane transporter activity
E1A90_RS16830	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS16835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E1A90_RS16840	COG5632	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS16840	COG3409	Peptidoglycan-binding domain 1 protein
E1A90_RS16850	COG0561	phosphatase activity
E1A90_RS16855	COG2094	Belongs to the DNA glycosylase MPG family
E1A90_RS16860	COG1216	Glycosyl transferase, family 2
E1A90_RS16865	COG0463	Glycosyl transferase, family 2
E1A90_RS16870	COG3527	Alpha-acetolactate decarboxylase
E1A90_RS16875	COG0028	Belongs to the TPP enzyme family
E1A90_RS16895	COG3679	Belongs to the UPF0342 family
E1A90_RS16900	COG4399	Belongs to the UPF0754 family
E1A90_RS16910	COG0189	ligase activity
E1A90_RS16925	COG1126	abc transporter atp-binding protein
E1A90_RS16930	COG0765	amino acid transport
E1A90_RS16935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A90_RS16940	COG1132	(ABC) transporter
E1A90_RS16945	COG1132	(ABC) transporter
E1A90_RS16960	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS16965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
E1A90_RS16970	COG0531	amino acid
E1A90_RS16980	COG0693	protein deglycase activity
E1A90_RS16990	COG2211	Major facilitator Superfamily
E1A90_RS16995	COG4533	DNA binding
E1A90_RS17010	COG1733	regulation of RNA biosynthetic process
E1A90_RS17015	COG2814	Major facilitator Superfamily
E1A90_RS17025	COG1309	transcriptional regulator
E1A90_RS17030	COG2076	Multidrug Resistance protein
E1A90_RS17045	COG0300	oxidoreductase activity
E1A90_RS17055	COG1522	sequence-specific DNA binding
E1A90_RS17060	COG0697	spore germination
E1A90_RS17080	COG2259	Doxx family
E1A90_RS17090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A90_RS17090	COG1263	PTS System
E1A90_RS17095	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E1A90_RS17100	COG1737	Transcriptional regulator
E1A90_RS17110	COG0475	glutathione-regulated potassium exporter activity
E1A90_RS17115	COG0531	amino acid
E1A90_RS17145	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS17175	COG3546	catalase activity
E1A90_RS17180	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS17185	COG0577	efflux transmembrane transporter activity
E1A90_RS17200	COG5522	Integral membrane protein (intg_mem_TP0381)
E1A90_RS17210	COG1136	(ABC) transporter
E1A90_RS17215	COG0577	efflux transmembrane transporter activity
E1A90_RS17220	COG1388	LysM domain
E1A90_RS17220	COG3584	3D domain protein
E1A90_RS17245	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E1A90_RS17250	COG1447	Phosphotransferase system cellobiose-specific component IIA
E1A90_RS17275	COG0604	alcohol dehydrogenase
E1A90_RS17280	COG1283	sodium-dependent phosphate transmembrane transporter activity
E1A90_RS17285	COG0604	alcohol dehydrogenase
E1A90_RS17290	COG1316	TRANSCRIPTIONal
E1A90_RS17300	COG0730	response to heat
E1A90_RS17305	COG2210	Belongs to the sulfur carrier protein TusA family
E1A90_RS17310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A90_RS17310	COG0425	Belongs to the sulfur carrier protein TusA family
E1A90_RS17315	COG0425	Belongs to the sulfur carrier protein TusA family
E1A90_RS17320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS17320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A90_RS17330	COG1937	Protein conserved in bacteria
E1A90_RS17370	COG0778	Nitroreductase
E1A90_RS17430	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS17435	COG2252	PERMEase
E1A90_RS17440	COG1879	ABC-type sugar transport system periplasmic component
E1A90_RS17445	COG1129	ABC transporter
E1A90_RS17450	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A90_RS17470	COG1846	Transcriptional regulator
E1A90_RS17475	COG2814	Major facilitator Superfamily
E1A90_RS17480	COG2205	protein histidine kinase activity
E1A90_RS17485	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
E1A90_RS17490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
E1A90_RS17520	COG0351	phosphomethylpyrimidine kinase
E1A90_RS17525	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A90_RS17530	COG2022	thiamine diphosphate biosynthetic process
E1A90_RS17535	COG2104	thiamine diphosphate biosynthetic process
E1A90_RS17540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E1A90_RS17545	COG0352	thiamine-phosphate diphosphorylase activity
E1A90_RS17565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
E1A90_RS17570	COG4991	sh3 domain protein
E1A90_RS17570	COG3103	Sh3 type 3 domain protein
E1A90_RS17570	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS17585	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
E1A90_RS17715	COG0581	inorganic phosphate transmembrane transporter activity
E1A90_RS17720	COG0573	inorganic phosphate transmembrane transporter activity
E1A90_RS17725	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E1A90_RS17735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E1A90_RS17740	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
E1A90_RS17755	COG0531	amino acid
E1A90_RS17760	COG0697	spore germination
E1A90_RS17765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
E1A90_RS17780	COG4990	cell redox homeostasis
E1A90_RS17785	COG0833	amino acid
E1A90_RS17795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
E1A90_RS17800	COG1845	cytochrome c oxidase, subunit III
E1A90_RS17815	COG0475	glutathione-regulated potassium exporter activity
E1A90_RS17815	COG0569	domain protein
E1A90_RS17840	COG2252	PERMEase
E1A90_RS17845	COG1113	amino acid transport
E1A90_RS17860	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS17865	COG3104	oligopeptide transport
E1A90_RS17885	COG1476	TRANSCRIPTIONal
E1A90_RS17890	COG1388	LysM domain
E1A90_RS17890	COG3584	3D domain protein
E1A90_RS17895	COG0840	transmembrane signaling receptor activity
E1A90_RS17940	COG1063	alcohol dehydrogenase
E1A90_RS17970	COG1879	ABC-type sugar transport system periplasmic component
E1A90_RS17975	COG1172	Belongs to the binding-protein-dependent transport system permease family
E1A90_RS17985	COG1869	D-ribose catabolic process
E1A90_RS17990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
E1A90_RS17995	COG1609	Transcriptional regulator
E1A90_RS18000	COG0477	Major facilitator Superfamily
E1A90_RS18005	COG1846	Transcriptional regulator
E1A90_RS18010	COG2271	Major facilitator Superfamily
E1A90_RS18020	COG4608	Belongs to the ABC transporter superfamily
E1A90_RS18025	COG0601	transmembrane transport
E1A90_RS18035	COG0747	negative chemotaxis
E1A90_RS18065	COG5002	protein histidine kinase activity
E1A90_RS18070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
E1A90_RS18105	COG0833	amino acid
E1A90_RS18110	COG0765	amino acid transport
E1A90_RS18115	COG0765	amino acid transport
E1A90_RS18120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A90_RS18125	COG1126	abc transporter atp-binding protein
E1A90_RS18130	COG1115	amino acid carrier protein
E1A90_RS18135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
E1A90_RS18150	COG1404	Belongs to the peptidase S8 family
E1A90_RS18160	COG4585	Histidine kinase
E1A90_RS18165	COG0697	spore germination
E1A90_RS18185	COG0366	Alpha amylase catalytic
E1A90_RS18190	COG1263	PTS System
E1A90_RS18190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A90_RS18195	COG2188	Transcriptional regulator
E1A90_RS18200	COG0531	amino acid
E1A90_RS18220	COG0714	Associated with various cellular activities
E1A90_RS18235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
E1A90_RS18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS18265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS18270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS18275	COG3104	oligopeptide transport
E1A90_RS18295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS18305	COG1027	Aspartate ammonia-lyase
E1A90_RS18310	COG1253	flavin adenine dinucleotide binding
E1A90_RS18315	COG0346	lactoylglutathione lyase activity
E1A90_RS18320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A90_RS18325	COG1316	TRANSCRIPTIONal
E1A90_RS18330	COG2720	vancomycin resistance protein
E1A90_RS18350	COG3227	Zinc metalloprotease (Elastase)
E1A90_RS18365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
E1A90_RS18370	COG2217	Heavy metal translocating P-type atpase
E1A90_RS18375	COG0640	Transcriptional regulator
E1A90_RS18385	COG0531	amino acid
E1A90_RS18400	COG2427	Protein of unknown function (DUF1641)
E1A90_RS18405	COG3383	formate dehydrogenase (NAD+) activity
E1A90_RS18410	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
E1A90_RS18415	COG0456	acetyltransferase
E1A90_RS18420	COG0745	RESPONSE REGULATOR receiver
E1A90_RS18425	COG5002	protein histidine kinase activity
E1A90_RS18435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS18440	COG0697	spore germination
E1A90_RS18450	COG0281	malic enzyme
E1A90_RS18455	COG3493	citrate carrier protein
E1A90_RS18460	COG4565	transcriptional regulatory protein
E1A90_RS18465	COG3290	protein histidine kinase activity
E1A90_RS18475	COG4990	cell redox homeostasis
E1A90_RS18485	COG5002	protein histidine kinase activity
E1A90_RS18490	COG0745	RESPONSE REGULATOR receiver
E1A90_RS18495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
E1A90_RS18505	COG0395	ABC-type sugar transport system, permease component
E1A90_RS18520	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
E1A90_RS18545	COG2851	Citrate transporter
E1A90_RS18550	COG4565	transcriptional regulatory protein
E1A90_RS18555	COG3290	protein histidine kinase activity
E1A90_RS18565	COG2268	Band 7 protein
E1A90_RS18570	COG1585	Membrane protein implicated in regulation of membrane protease activity
E1A90_RS18585	COG2718	Belongs to the UPF0229 family
E1A90_RS18600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
E1A90_RS18620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
E1A90_RS18625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
E1A90_RS18745	COG0735	belongs to the Fur family
E1A90_RS18750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E1A90_RS18770	COG4555	ABC transporter
E1A90_RS18775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E1A90_RS18785	COG4129	membrane
E1A90_RS18790	COG1132	(ABC) transporter
E1A90_RS18795	COG3557	Belongs to the UPF0374 family
E1A90_RS18815	COG1194	a g-specific adenine glycosylase
E1A90_RS18855	COG1228	amidohydrolase
E1A90_RS18875	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
E1A90_RS18890	COG0463	Glycosyl transferase, family 2
E1A90_RS18905	COG1216	Glycosyl transferase, family 2
E1A90_RS18920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
E1A90_RS18925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A90_RS18925	COG1263	PTS System
E1A90_RS18935	COG2066	Belongs to the glutaminase family
E1A90_RS18955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E1A90_RS18970	COG3829	transcription factor binding
E1A90_RS18990	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
E1A90_RS19010	COG0535	radical SAM domain protein
E1A90_RS19020	COG0387	Pfam Sodium calcium exchanger
E1A90_RS19025	COG3871	stress protein (general stress protein 26)
E1A90_RS19040	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS19060	COG0697	spore germination
E1A90_RS19065	COG2217	Heavy metal translocating P-type atpase
E1A90_RS19070	COG1295	ribonuclease BN
E1A90_RS19080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
E1A90_RS19085	COG4840	Belongs to the UPF0435 family
E1A90_RS19095	COG3853	Toxic anion resistance protein (TelA)
E1A90_RS19110	COG2310	stress, protein
E1A90_RS19115	COG2310	stress, protein
E1A90_RS19120	COG2310	stress, protein
E1A90_RS19150	COG2270	Major facilitator Superfamily
E1A90_RS19195	COG0488	(ABC) transporter
E1A90_RS19200	COG1116	anion transmembrane transporter activity
E1A90_RS19210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
E1A90_RS19230	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
E1A90_RS19240	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
E1A90_RS19260	COG2190	(PTS) system
E1A90_RS19260	COG1263	PTS System
E1A90_RS19260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A90_RS19265	COG0366	Alpha amylase catalytic
E1A90_RS19270	COG0277	FAD linked oxidase domain protein
E1A90_RS19285	COG0549	Belongs to the carbamate kinase family
E1A90_RS19310	COG0840	transmembrane signaling receptor activity
E1A90_RS19325	COG0765	amino acid transport
E1A90_RS19335	COG0723	plastoquinol--plastocyanin reductase activity
E1A90_RS19335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
E1A90_RS19340	COG2814	Major facilitator Superfamily
E1A90_RS19345	COG3541	Predicted nucleotidyltransferase
E1A90_RS19365	COG5002	protein histidine kinase activity
E1A90_RS19390	COG0166	Belongs to the GPI family
E1A90_RS19400	COG0492	ferredoxin-NADP+ reductase activity
E1A90_RS19410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS19415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS19420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS19430	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
E1A90_RS19440	COG0450	alkyl hydroperoxide reductase
E1A90_RS19455	COG1473	amidohydrolase
E1A90_RS19460	COG1757	Na H antiporter
E1A90_RS19485	COG4807	Protein conserved in bacteria
E1A90_RS19495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E1A90_RS19505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A90_RS19520	COG2309	aminopeptidase activity
E1A90_RS19530	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS19545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS19550	COG0546	phosphoglycolate phosphatase activity
E1A90_RS19555	COG1597	lipid kinase activity
E1A90_RS19560	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
E1A90_RS19565	COG0154	amidase activity
E1A90_RS19575	COG4682	membrane
E1A90_RS19580	COG1846	Transcriptional regulator
E1A90_RS19585	COG0003	Pfam Anion-transporting ATPase
E1A90_RS19600	COG1464	Belongs to the NlpA lipoprotein family
E1A90_RS19605	COG2011	ABC-type metal ion transport system permease component
E1A90_RS19635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
E1A90_RS19645	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
E1A90_RS19670	COG0151	Belongs to the GarS family
E1A90_RS19680	COG0138	bifunctional purine biosynthesis protein purh
E1A90_RS19685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
E1A90_RS19690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
E1A90_RS19695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
E1A90_RS19705	COG0047	phosphoribosylformylglycinamidine synthase activity
E1A90_RS19710	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
E1A90_RS19715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
E1A90_RS19720	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
E1A90_RS19725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
E1A90_RS19730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
E1A90_RS19760	COG0697	spore germination
E1A90_RS19780	COG0745	RESPONSE REGULATOR receiver
E1A90_RS19785	COG2205	protein histidine kinase activity
E1A90_RS19850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
E1A90_RS19880	COG5002	protein histidine kinase activity
E1A90_RS19890	COG2252	PERMEase
E1A90_RS19895	COG0519	Catalyzes the synthesis of GMP from XMP
E1A90_RS19895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
E1A90_RS19900	COG0459	protein refolding
E1A90_RS19905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
E1A90_RS19910	COG1266	CAAX protease self-immunity
E1A90_RS19920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
E1A90_RS19925	COG0488	(ABC) transporter
E1A90_RS19935	COG0456	acetyltransferase
E1A90_RS19945	COG0802	atpase or kinase
E1A90_RS20045	COG2183	response to ionizing radiation
E1A90_RS20050	COG2337	Toxic component of a toxin-antitoxin (TA) module
E1A90_RS20055	COG0864	Transcriptional regulator
E1A90_RS20060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
E1A90_RS20065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
E1A90_RS20070	COG0736	holo-[acyl-carrier-protein] synthase activity
E1A90_RS20075	COG0705	Rhomboid family
E1A90_RS20080	COG4294	response to UV
E1A90_RS20090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
E1A90_RS20100	COG2814	Major facilitator Superfamily
E1A90_RS20105	COG0531	amino acid
E1A90_RS20115	COG0179	Fumarylacetoacetate (FAA) hydrolase
E1A90_RS20120	COG3185	4-Hydroxyphenylpyruvate dioxygenase
E1A90_RS20150	COG0561	phosphatase activity
E1A90_RS20155	COG4608	Belongs to the ABC transporter superfamily
E1A90_RS20160	COG0444	Belongs to the ABC transporter superfamily
E1A90_RS20170	COG0601	transmembrane transport
E1A90_RS20180	COG0747	negative chemotaxis
E1A90_RS20190	COG0842	Transport permease protein
E1A90_RS20200	COG1131	(ABC) transporter
E1A90_RS20205	COG2197	response regulator
E1A90_RS20210	COG4585	Histidine kinase
E1A90_RS20215	COG0488	(ABC) transporter
E1A90_RS20255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS20265	COG1609	Transcriptional regulator
E1A90_RS20275	COG0204	Acyl-transferase
E1A90_RS20290	COG0697	spore germination
E1A90_RS20305	COG1910	domain protein
E1A90_RS20310	COG0725	ABC transporter, periplasmic molybdate-binding protein
E1A90_RS20315	COG4149	molybdate abc transporter
E1A90_RS20330	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E1A90_RS20335	COG0656	L-ascorbic acid biosynthetic process
E1A90_RS20340	COG4166	transmembrane transport
E1A90_RS20345	COG4166	transmembrane transport
E1A90_RS20360	COG2207	Transcriptional regulator
E1A90_RS20370	COG4166	transmembrane transport
E1A90_RS20375	COG4608	Belongs to the ABC transporter superfamily
E1A90_RS20380	COG0444	Belongs to the ABC transporter superfamily
E1A90_RS20385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
E1A90_RS20390	COG0601	transmembrane transport
E1A90_RS20410	COG2814	Major facilitator Superfamily
E1A90_RS20420	COG2271	Major facilitator Superfamily
E1A90_RS20425	COG0277	FAD linked oxidase domain protein
E1A90_RS20435	COG0604	alcohol dehydrogenase
E1A90_RS20440	COG1464	Belongs to the NlpA lipoprotein family
E1A90_RS20450	COG2011	ABC-type metal ion transport system permease component
E1A90_RS20455	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS20495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E1A90_RS20505	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
E1A90_RS20585	COG0726	polysaccharide deacetylase
E1A90_RS20590	COG2194	sulfuric ester hydrolase activity
E1A90_RS20600	COG0489	protein tyrosine kinase activity
E1A90_RS20605	COG0860	N-Acetylmuramoyl-L-alanine amidase
E1A90_RS20615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
E1A90_RS20620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
E1A90_RS20630	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
E1A90_RS20655	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
E1A90_RS20660	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E1A90_RS20665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
E1A90_RS20675	COG0024	Methionine aminopeptidase
E1A90_RS20680	COG0563	adenylate kinase activity
E1A90_RS20685	COG0201	protein transport
E1A90_RS20690	COG0200	Binds to the 23S rRNA
E1A90_RS20695	COG1841	ribosomal large subunit assembly
E1A90_RS20705	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
E1A90_RS20715	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
E1A90_RS20725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E1A90_RS20730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
E1A90_RS20745	COG0255	Belongs to the universal ribosomal protein uL29 family
E1A90_RS20760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
E1A90_RS20765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
E1A90_RS20770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E1A90_RS20780	COG0088	Forms part of the polypeptide exit tunnel
E1A90_RS20785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
E1A90_RS20790	COG0051	transcription antitermination factor activity, RNA binding
E1A90_RS20795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
E1A90_RS20800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
E1A90_RS20810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
E1A90_RS20815	COG1358	cellular component organization or biogenesis
E1A90_RS20820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
E1A90_RS20825	COG0085	RNA polymerase activity
E1A90_RS20830	COG2813	Specifically methylates the guanine in position
E1A90_RS20835	COG0222	ribosome binding
E1A90_RS20840	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
E1A90_RS20845	COG0081	regulation of translation
E1A90_RS20855	COG0250	Participates in transcription elongation, termination and antitermination
E1A90_RS20860	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E1A90_RS20880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1A90_RS20890	COG0215	cysteine-tRNA ligase activity
E1A90_RS20895	COG1045	serine acetyltransferase
E1A90_RS20900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
E1A90_RS20910	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
E1A90_RS20920	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
E1A90_RS20925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
E1A90_RS20930	COG0542	response to heat
E1A90_RS20935	COG3869	Catalyzes the specific phosphorylation of arginine residues in
E1A90_RS20940	COG3880	PFAM UvrB UvrC protein
E1A90_RS21030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
E1A90_RS21035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
E1A90_RS21040	COG1396	sequence-specific DNA binding
E1A90_RS21045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
E1A90_RS21050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
E1A90_RS21055	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
E1A90_RS21060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
E1A90_RS21065	COG0512	Glutamine amidotransferase of anthranilate synthase
E1A90_RS21070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
E1A90_RS21075	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
E1A90_RS21080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
E1A90_RS21085	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
E1A90_RS21090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
E1A90_RS21095	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E1A90_RS21140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
E1A90_RS21150	COG2244	polysaccharide biosynthetic process
E1A90_RS21155	COG2002	toxin-antitoxin pair type II binding
E1A90_RS21180	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
E1A90_RS21185	COG2088	sporulation resulting in formation of a cellular spore
E1A90_RS21190	COG0251	oxidation-reduction process
E1A90_RS21195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E1A90_RS21200	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
E1A90_RS21210	COG4466	Protein conserved in bacteria
E1A90_RS21220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
E1A90_RS21230	COG0084	hydrolase, TatD family'
E1A90_RS21240	COG2002	toxin-antitoxin pair type II binding
E1A90_RS21245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
E1A90_RS21250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
E1A90_RS21255	COG4467	Involved in initiation control of chromosome replication
E1A90_RS21260	COG1774	PSP1 C-terminal conserved region
E1A90_RS21265	COG0470	DNA polymerase III
E1A90_RS21270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
E1A90_RS21275	COG1982	Orn Lys Arg decarboxylase major
E1A90_RS21320	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
E1A90_RS21325	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
E1A90_RS21330	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
E1A90_RS21340	COG0590	tRNA wobble adenosine to inosine editing
E1A90_RS21345	COG1335	isochorismatase
E1A90_RS21350	COG1428	Deoxynucleoside kinase
E1A90_RS21355	COG1428	Deoxynucleoside kinase
E1A90_RS21375	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
E1A90_RS21380	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
E1A90_RS21385	COG1686	Belongs to the peptidase S11 family
E1A90_RS21390	COG0517	IMP dehydrogenase activity
E1A90_RS21390	COG0516	GMP reductase activity
E1A90_RS21430	COG0187	DNA topoisomerase II activity
E1A90_RS21435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
E1A90_RS21440	COG2501	S4 domain
E1A90_RS21445	COG0592	DNA-directed DNA polymerase activity
E1A90_RS21455	COG0230	Belongs to the bacterial ribosomal protein bL34 family
E1A90_RS21465	COG0706	membrane insertase activity
E1A90_RS21475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
E1A90_RS21480	COG0445	tRNA wobble uridine modification
E1A90_RS21490	COG1475	DNA binding
E1A90_RS21500	COG1475	DNA binding
E1A90_RS21510	COG0668	transmembrane transport
E1A90_RS21515	COG4481	Protein conserved in bacteria
E1A90_RS21520	COG0012	GTP binding
E1A90_RS21525	COG0360	Binds together with S18 to 16S ribosomal RNA
E1A90_RS21530	COG0629	single-stranded DNA binding
E1A90_RS21550	COG0359	binds to the 23S rRNA
E1A90_RS21555	COG0305	Participates in initiation and elongation during chromosome replication
E1A90_RS21585	COG0745	RESPONSE REGULATOR receiver
E1A90_RS21590	COG5002	protein histidine kinase activity
E1A90_RS21600	COG4853	Protein conserved in bacteria
E1A90_RS21605	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
E1A90_RS21620	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
E1A90_RS21660	COG1272	protein, Hemolysin III
E1A90_RS21665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E1A90_RS21715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E1A90_RS21730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1A90_RS21735	COG2814	Major facilitator Superfamily
E1A90_RS21740	COG3275	phosphorelay sensor kinase activity
E1A90_RS21745	COG3279	Response regulator of the LytR AlgR family
E1A90_RS21750	COG1380	Effector of murein hydrolase LrgA
E1A90_RS21755	COG1346	cytolysis
E1A90_RS21760	COG0628	permease
E1A90_RS21765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E1A90_RS21765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
E1A90_RS21775	COG1309	transcriptional regulator
E1A90_RS21785	COG1696	Membrane protein involved in D-alanine export
E1A90_RS21790	COG0488	(ABC) transporter
E1A90_RS21795	COG1216	Glycosyl transferase, family 2
E1A90_RS21810	COG1216	Glycosyl transferase, family 2
E1A90_RS21815	COG1607	acyl-coa hydrolase
E1A90_RS21825	COG0840	transmembrane signaling receptor activity
E1A90_RS21855	COG0477	Major facilitator Superfamily
E1A90_RS21860	COG3279	Response regulator of the LytR AlgR family
E1A90_RS21865	COG1966	Carbon starvation protein
E1A90_RS21870	COG2879	small protein
E1A90_RS21875	COG3706	GGDEF domain
E1A90_RS21885	COG4585	Histidine kinase
E1A90_RS21885	COG2203	Gaf domain
E1A90_RS21890	COG2197	response regulator
E1A90_RS21910	COG2873	o-acetylhomoserine
E1A90_RS21915	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
E1A90_RS21920	COG0460	homoserine dehydrogenase
E1A90_RS21930	COG1609	Transcriptional regulator
E1A90_RS21935	COG2755	lipolytic protein G-D-S-L family
E1A90_RS21940	COG1131	(ABC) transporter
E1A90_RS21945	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
E1A90_RS21950	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
E1A90_RS21955	COG2814	Major facilitator Superfamily
E1A90_RS21960	COG0561	phosphatase activity
E1A90_RS21965	COG2233	PERMEase
E1A90_RS21980	COG2363	Small membrane protein
E1A90_RS21990	COG3773	Cell wall hydrolase
E1A90_RS22000	COG3253	May function as heme-dependent peroxidase
E1A90_RS22005	COG0280	phosphate acetyltransferase
E1A90_RS22020	COG4844	belongs to the
E1A90_RS22025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS22030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
E1A90_RS22035	COG1120	ATPase activity
E1A90_RS22040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS22045	COG1078	dGTPase activity
E1A90_RS22055	COG1994	Peptidase M50
E1A90_RS22065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
E1A90_RS22070	COG0584	glycerophosphoryl diester phosphodiesterase
E1A90_RS22075	COG0789	Transcriptional regulator
E1A90_RS22080	COG2814	Major facilitator Superfamily
E1A90_RS22090	COG0010	Belongs to the arginase family
E1A90_RS22105	COG1619	proteins homologs of microcin C7 resistance protein MccF
E1A90_RS22110	COG4506	Protein conserved in bacteria
E1A90_RS22125	COG2234	aminopeptidase activity
E1A90_RS22135	COG0024	Methionine aminopeptidase
E1A90_RS22140	COG1131	(ABC) transporter
E1A90_RS22145	COG0842	Transport permease protein
E1A90_RS22155	COG2197	response regulator
E1A90_RS22180	COG5001	Diguanylate cyclase
E1A90_RS22180	COG3300	MHYT domain
E1A90_RS22190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
E1A90_RS22195	COG2181	nitrate reductase activity
E1A90_RS22195	COG0247	lactate metabolic process
E1A90_RS22200	COG0183	Belongs to the thiolase family
E1A90_RS22210	COG1960	acyl-CoA dehydrogenase activity
E1A90_RS22215	COG1960	acyl-CoA dehydrogenase activity
E1A90_RS22225	COG3343	RNA polymerase activity
E1A90_RS22235	COG4821	SIS domain
E1A90_RS22260	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
E1A90_RS22270	COG1435	thymidine kinase activity
E1A90_RS22275	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
E1A90_RS22280	COG2890	protein-(glutamine-N5) methyltransferase activity
E1A90_RS22300	COG1971	Probably functions as a manganese efflux pump
E1A90_RS22310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
E1A90_RS22315	COG2259	Doxx family
E1A90_RS22320	COG2190	(PTS) system
E1A90_RS22330	COG0698	ribose 5-phosphate isomerase
E1A90_RS22340	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
E1A90_RS22365	COG0356	it plays a direct role in the translocation of protons across the membrane
E1A90_RS22375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
E1A90_RS22385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
E1A90_RS22390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
E1A90_RS22395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
E1A90_RS22400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
E1A90_RS22420	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A90_RS22425	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A90_RS22430	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A90_RS22435	COG0649	NAD binding
E1A90_RS22440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
E1A90_RS22450	COG0839	Belongs to the complex I subunit 6 family
E1A90_RS22455	COG0713	ATP synthesis coupled electron transport
E1A90_RS22460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
E1A90_RS22465	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
E1A90_RS22470	COG1007	ATP synthesis coupled electron transport
E1A90_RS22475	COG4836	Membrane
E1A90_RS22495	COG3279	Response regulator of the LytR AlgR family
E1A90_RS22510	COG0739	heme binding
E1A90_RS22525	COG1609	Transcriptional regulator
E1A90_RS22540	COG0489	protein tyrosine kinase activity
E1A90_RS22550	COG0489	protein tyrosine kinase activity
E1A90_RS22555	COG4464	protein tyrosine phosphatase activity
E1A90_RS22560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E1A90_RS22585	COG1215	transferase activity, transferring glycosyl groups
E1A90_RS22590	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E1A90_RS22595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E1A90_RS22610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
E1A90_RS22615	COG0745	RESPONSE REGULATOR receiver
E1A90_RS22620	COG3850	Histidine kinase
E1A90_RS22620	COG5002	protein histidine kinase activity
E1A90_RS22645	COG1136	(ABC) transporter
E1A90_RS22650	COG0577	efflux transmembrane transporter activity
E1A90_RS22695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E1A90_RS22700	COG4715	Zinc finger, swim domain protein
E1A90_RS22725	COG1388	LysM domain
E1A90_RS22725	COG3584	3D domain protein
E1A90_RS22735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
E1A90_RS22740	COG1215	transferase activity, transferring glycosyl groups
E1A90_RS22750	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A90_RS22755	COG0791	NLP P60 protein
E1A90_RS22755	COG1388	LysM domain
E1A90_RS22765	COG1368	sulfuric ester hydrolase activity
E1A90_RS22780	COG2389	metal-binding protein
E1A90_RS22795	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
E1A90_RS22800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E1A90_RS22805	COG1294	oxidase, subunit
E1A90_RS22810	COG1271	oxidase subunit
E1A90_RS22815	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
E1A90_RS22820	COG0583	DNA-binding transcription factor activity
E1A90_RS22825	COG1511	domain protein
E1A90_RS22845	COG1301	dicarboxylic acid transport
E1A90_RS22850	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E1A90_RS22860	COG1447	Phosphotransferase system cellobiose-specific component IIA
E1A90_RS22885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
E1A90_RS22890	COG1447	Phosphotransferase system cellobiose-specific component IIA
E1A90_RS22895	COG1486	melibiose metabolic process
E1A90_RS22915	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
E1A90_RS22915	COG3933	PFAM sigma-54 factor interaction domain-containing protein
E1A90_RS22925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E1A90_RS22930	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
E1A90_RS22935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
E1A90_RS22945	COG1739	Uncharacterized protein family UPF0029
E1A90_RS22950	COG1307	EDD domain protein, DegV family
E1A90_RS22955	COG1733	regulation of RNA biosynthetic process
E1A90_RS22960	COG1388	LysM domain
E1A90_RS22960	COG0791	NLP P60 protein
E1A90_RS22965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
E1A90_RS22970	COG1040	competence protein
E1A90_RS22975	COG1278	Cold shock
E1A90_RS23015	COG2884	Cell division ATP-binding protein ftsE
E1A90_RS23020	COG2177	Part of the ABC transporter FtsEX involved in
E1A90_RS23025	COG3409	Peptidoglycan-binding domain 1 protein
E1A90_RS23025	COG0793	Belongs to the peptidase S41A family
E1A90_RS23030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
E1A90_RS23035	COG1132	(ABC) transporter
E1A90_RS23045	COG0488	(ABC) transporter
E1A90_RS23050	COG0655	NAD(P)H dehydrogenase (quinone) activity
E1A90_RS23055	COG0789	Transcriptional regulator
E1A90_RS23060	COG0583	DNA-binding transcription factor activity
E1A90_RS23095	COG0789	Transcriptional regulator
E1A90_RS23125	COG1950	PFAM Membrane protein of
E1A90_RS23130	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
E1A90_RS23135	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
E1A90_RS23140	COG0546	phosphoglycolate phosphatase activity
E1A90_RS23145	COG0110	maltose O-acetyltransferase activity
E1A90_RS23150	COG0457	Tetratricopeptide repeat
E1A90_RS23155	COG0492	ferredoxin-NADP+ reductase activity
E1A90_RS23165	COG1051	belongs to the nudix hydrolase family
E1A90_RS23170	COG1660	Displays ATPase and GTPase activities
E1A90_RS23175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
E1A90_RS23180	COG1481	regulation of sporulation
E1A90_RS23185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
E1A90_RS23210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E1A90_RS23260	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E1A90_RS23265	COG0126	phosphoglycerate kinase activity
E1A90_RS23270	COG0149	triose-phosphate isomerase activity
E1A90_RS23280	COG0148	phosphopyruvate hydratase activity
E1A90_RS23295	COG1346	cytolysis
E1A90_RS23300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
E1A90_RS23305	COG1647	Serine aminopeptidase, S33
E1A90_RS23315	COG0557	exoribonuclease II activity
E1A90_RS23325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
E1A90_RS23365	COG2233	PERMEase
E1A90_RS23370	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
E1A90_RS23375	COG0288	reversible hydration of carbon dioxide
E1A90_RS23380	COG1522	sequence-specific DNA binding
E1A90_RS23390	COG1522	sequence-specific DNA binding
E1A90_RS23395	COG1335	isochorismatase
E1A90_RS23400	COG4224	UPF0291 protein
E1A90_RS23405	COG0778	Nitroreductase
E1A90_RS23410	COG1733	regulation of RNA biosynthetic process
E1A90_RS23420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS23425	COG0488	(ABC) transporter
E1A90_RS23460	COG3290	protein histidine kinase activity
E1A90_RS23460	COG0840	transmembrane signaling receptor activity
E1A90_RS23480	COG1252	NADH dehydrogenase
E1A90_RS23490	COG1733	regulation of RNA biosynthetic process
E1A90_RS23500	COG0656	L-ascorbic acid biosynthetic process
E1A90_RS23520	COG2910	NAD(P)H-binding
E1A90_RS23525	COG1115	amino acid carrier protein
E1A90_RS23535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
E1A90_RS23545	COG1528	Iron-storage protein
E1A90_RS23555	COG1611	Belongs to the LOG family
E1A90_RS23565	COG2318	DinB family
E1A90_RS23580	COG0783	Belongs to the Dps family
E1A90_RS23585	COG1115	amino acid carrier protein
E1A90_RS23590	COG0490	domain, Protein
E1A90_RS23595	COG0475	glutathione-regulated potassium exporter activity
E1A90_RS23600	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS23615	COG1741	Belongs to the pirin family
E1A90_RS23620	COG3227	Zinc metalloprotease (Elastase)
E1A90_RS23625	COG2151	metal-sulfur cluster biosynthetic enzyme
E1A90_RS23635	COG0840	transmembrane signaling receptor activity
E1A90_RS23655	COG5002	protein histidine kinase activity
E1A90_RS23660	COG0745	RESPONSE REGULATOR receiver
E1A90_RS23665	COG1376	ErfK ybiS ycfS ynhG family protein
E1A90_RS23710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS23735	COG0531	amino acid
E1A90_RS23740	COG2814	Major facilitator Superfamily
E1A90_RS23760	COG0840	transmembrane signaling receptor activity
E1A90_RS23765	COG0011	TIGRFAM Protein of
E1A90_RS23775	COG0506	proline dehydrogenase activity
E1A90_RS23780	COG1686	Belongs to the peptidase S11 family
E1A90_RS23790	COG1250	3-hydroxyacyl-CoA dehydrogenase
E1A90_RS23790	COG1024	Enoyl-CoA hydratase
E1A90_RS23795	COG0183	Belongs to the thiolase family
E1A90_RS23800	COG1960	acyl-CoA dehydrogenase activity
E1A90_RS23805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS23810	COG1309	transcriptional regulator
E1A90_RS23885	COG1393	Belongs to the ArsC family
E1A90_RS23890	COG0509	glycine decarboxylation via glycine cleavage system
E1A90_RS23895	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
E1A90_RS23900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS23920	COG2011	ABC-type metal ion transport system permease component
E1A90_RS23925	COG1464	Belongs to the NlpA lipoprotein family
E1A90_RS23930	COG1464	Belongs to the NlpA lipoprotein family
E1A90_RS23935	COG0396	ATPase activity
E1A90_RS23940	COG0719	Fe-S assembly protein
E1A90_RS23945	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
E1A90_RS23950	COG0822	iron-sulfur transferase activity
E1A90_RS23955	COG0719	Fe-S assembly protein
E1A90_RS23960	COG0737	Belongs to the 5'-nucleotidase family
E1A90_RS23965	COG3377	Domain of unknown function (DUF1805)
E1A90_RS23980	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
E1A90_RS24000	COG4377	Putative membrane peptidase family (DUF2324)
E1A90_RS24005	COG0789	Transcriptional regulator
E1A90_RS24015	COG4470	Protein conserved in bacteria
E1A90_RS24035	COG1494	fructose-1,6-bisphosphatase
E1A90_RS24040	COG2445	Protein of unknown function DUF86
E1A90_RS24050	COG0647	UMP catabolic process
E1A90_RS24060	COG2249	NAD(P)H dehydrogenase (quinone) activity
E1A90_RS24080	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
E1A90_RS24095	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
E1A90_RS24100	COG4837	Protein of unknown function (DUF1462)
E1A90_RS24150	COG2824	Alkylphosphonate utilization operon protein PhnA
E1A90_RS24155	COG0390	transport system, permease component
E1A90_RS24165	COG1252	NADH dehydrogenase
E1A90_RS24175	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
E1A90_RS24180	COG0316	Belongs to the HesB IscA family
E1A90_RS24205	COG1683	Conserved Protein
E1A90_RS24225	COG3708	Transcriptional regulator
E1A90_RS24230	COG0492	ferredoxin-NADP+ reductase activity
E1A90_RS24235	COG1252	NADH dehydrogenase
E1A90_RS24255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
E1A90_RS24265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
E1A90_RS24270	COG1210	Utp--glucose-1-phosphate uridylyltransferase
E1A90_RS24275	COG1268	BioY protein
E1A90_RS24285	COG2050	protein possibly involved in aromatic compounds catabolism
E1A90_RS24305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
E1A90_RS24310	COG5018	Exonuclease
E1A90_RS24325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
E1A90_RS24340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E1A90_RS24345	COG1522	sequence-specific DNA binding
E1A90_RS24350	COG0436	Aminotransferase
E1A90_RS24355	COG1098	S1 RNA binding domain
E1A90_RS24360	COG2155	Conserved Protein
E1A90_RS24370	COG0166	Belongs to the GPI family
E1A90_RS24385	COG1285	pathogenesis
E1A90_RS24530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
E1A90_RS24535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
E1A90_RS24540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
E1A90_RS24550	COG0058	SHG alpha-glucan phosphorylase activity
E1A90_RS24575	COG1278	Cold shock
E1A90_RS24580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
E1A90_RS24590	COG1575	Belongs to the MenA family. Type 1 subfamily
E1A90_RS24595	COG1169	isochorismate synthase
E1A90_RS24605	COG0596	Alpha beta hydrolase
E1A90_RS24610	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
E1A90_RS24615	COG0318	PFAM AMP-dependent synthetase and ligase
E1A90_RS24620	COG4948	Mandelate Racemase Muconate Lactonizing
E1A90_RS24640	COG3964	amidohydrolase
E1A90_RS24660	COG2188	Transcriptional regulator
E1A90_RS24675	COG0577	efflux transmembrane transporter activity
E1A90_RS24680	COG1136	(ABC) transporter
E1A90_RS24685	COG0577	efflux transmembrane transporter activity
E1A90_RS24695	COG2205	protein histidine kinase activity
E1A90_RS24700	COG0745	RESPONSE REGULATOR receiver
E1A90_RS24705	COG0640	Transcriptional regulator
E1A90_RS24710	COG5658	integral membrane protein
E1A90_RS24715	COG1131	(ABC) transporter
E1A90_RS24725	COG2207	Transcriptional regulator
E1A90_RS24725	COG3708	Transcriptional regulator
E1A90_RS24730	COG1136	(ABC) transporter
E1A90_RS24735	COG0577	efflux transmembrane transporter activity
E1A90_RS24745	COG0586	Pfam SNARE associated Golgi protein
E1A90_RS24770	COG1136	(ABC) transporter
E1A90_RS24785	COG1597	lipid kinase activity
E1A90_RS24790	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
E1A90_RS24815	COG0745	RESPONSE REGULATOR receiver
E1A90_RS24820	COG5002	protein histidine kinase activity
E1A90_RS24850	COG1842	Phage shock protein A
E1A90_RS24875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS24890	COG1294	oxidase, subunit
E1A90_RS24895	COG1271	oxidase subunit
E1A90_RS24900	COG0288	reversible hydration of carbon dioxide
E1A90_RS24910	COG1854	S-ribosylhomocysteine lyase activity
E1A90_RS24915	COG0789	Transcriptional regulator
E1A90_RS24920	COG2076	Multidrug Resistance protein
E1A90_RS24925	COG2076	Multidrug Resistance protein
E1A90_RS24965	COG0494	nUDIX hydrolase
E1A90_RS24990	COG1116	anion transmembrane transporter activity
E1A90_RS24995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
E1A90_RS25010	COG4895	conserved protein (DUF2196)
E1A90_RS25020	COG1368	sulfuric ester hydrolase activity
E1A90_RS25030	COG2267	carboxylic ester hydrolase activity
E1A90_RS25035	COG0753	catalase activity
E1A90_RS25045	COG5002	protein histidine kinase activity
E1A90_RS25070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
E1A90_RS25075	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
E1A90_RS25105	COG0671	phosphoesterase, PA-phosphatase related
E1A90_RS25110	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
E1A90_RS25115	COG2267	carboxylic ester hydrolase activity
E1A90_RS25135	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
E1A90_RS25140	COG1242	4 iron, 4 sulfur cluster binding
E1A90_RS25160	COG1136	(ABC) transporter
E1A90_RS25175	COG0582	viral genome integration into host DNA
E1A90_RS25180	COG0490	domain, Protein
E1A90_RS25185	COG0475	glutathione-regulated potassium exporter activity
E1A90_RS25190	COG2814	Major facilitator Superfamily
E1A90_RS25195	COG0495	leucyl-tRNA aminoacylation
E1A90_RS25235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
E1A90_RS25245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
E1A90_RS25270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
E1A90_RS25275	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
E1A90_RS25280	COG0315	cyclic pyranopterin monophosphate synthase activity
E1A90_RS25285	COG0303	'Molybdopterin
E1A90_RS25290	COG1763	Mo-molybdopterin cofactor biosynthetic process
E1A90_RS25295	COG0314	molybdopterin synthase activity
E1A90_RS25320	COG1329	Transcriptional regulator
E1A90_RS25340	COG3832	glyoxalase III activity
E1A90_RS25350	COG2814	Major facilitator Superfamily
E1A90_RS25355	COG2081	HI0933 family
E1A90_RS25360	COG2244	polysaccharide biosynthetic process
E1A90_RS25365	COG1187	pseudouridine synthase activity
E1A90_RS25370	COG1349	DNA-binding transcription factor activity
E1A90_RS25375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
E1A90_RS25385	COG1523	belongs to the glycosyl hydrolase 13 family
E1A90_RS25390	COG0510	thiamine kinase activity
E1A90_RS25400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
E1A90_RS25405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS25415	COG1363	Peptidase, m42
E1A90_RS25420	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
E1A90_RS25425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
E1A90_RS25430	COG4848	Belongs to the UPF0354 family
E1A90_RS25435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
E1A90_RS25465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
E1A90_RS25470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS25490	COG2309	aminopeptidase activity
E1A90_RS25510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
E1A90_RS25510	COG1605	Chorismate mutase
E1A90_RS25520	COG1609	Transcriptional regulator
E1A90_RS25540	COG1970	mechanosensitive ion channel activity
E1A90_RS25550	COG0666	response to abiotic stimulus
E1A90_RS25555	COG5002	protein histidine kinase activity
E1A90_RS25560	COG0745	RESPONSE REGULATOR receiver
E1A90_RS25575	COG0123	including yeast histone deacetylase and acetoin utilization protein
E1A90_RS25585	COG0454	-acetyltransferase
E1A90_RS25590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1A90_RS25595	COG0110	maltose O-acetyltransferase activity
E1A90_RS25605	COG1595	DNA-templated transcription, initiation
E1A90_RS25665	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
E1A90_RS25675	COG0626	cystathionine gamma-synthase activity
E1A90_RS25680	COG1956	GAF domain-containing protein
E1A90_RS25685	COG1309	transcriptional regulator
E1A90_RS25695	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
E1A90_RS25700	COG1104	cysteine desulfurase activity
E1A90_RS25715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
E1A90_RS25725	COG1574	metal-dependent hydrolase with the TIM-barrel fold
E1A90_RS25740	COG3874	Sporulation protein YtfJ
E1A90_RS25745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
E1A90_RS25750	COG0827	DNA restriction-modification system
E1A90_RS25755	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
E1A90_RS25775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS25790	COG0137	argininosuccinate synthase activity
E1A90_RS25820	COG0589	response to stress
E1A90_RS25825	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS25840	COG1476	TRANSCRIPTIONal
E1A90_RS25850	COG0662	Cupin 2, conserved barrel domain protein
E1A90_RS25895	COG0006	proline dipeptidase activity
E1A90_RS25900	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
E1A90_RS25905	COG4109	DRTGG domain
E1A90_RS25925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
E1A90_RS25945	COG0281	malic enzyme
E1A90_RS25950	COG1725	Transcriptional regulator
E1A90_RS25955	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
E1A90_RS25965	COG0205	6-phosphofructokinase activity
E1A90_RS25975	COG3030	protein affecting phage T7 exclusion by the F plasmid
E1A90_RS25980	COG0628	permease
E1A90_RS25995	COG0372	Belongs to the citrate synthase family
E1A90_RS26000	COG0538	isocitrate dehydrogenase activity
E1A90_RS26005	COG0039	L-malate dehydrogenase activity
E1A90_RS26020	COG0745	RESPONSE REGULATOR receiver
E1A90_RS26025	COG5002	protein histidine kinase activity
E1A90_RS26030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1A90_RS26030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
E1A90_RS26040	COG1971	Probably functions as a manganese efflux pump
E1A90_RS26045	COG0237	dephospho-CoA kinase activity
E1A90_RS26050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
E1A90_RS26055	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
E1A90_RS26060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
E1A90_RS26065	COG3611	Membrane attachment protein
E1A90_RS26070	COG1484	DNA-dependent DNA replication
E1A90_RS26080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
E1A90_RS26095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
E1A90_RS26105	COG1363	Peptidase, m42
E1A90_RS26110	COG1309	transcriptional regulator
E1A90_RS26115	COG1566	PFAM secretion protein HlyD family protein
E1A90_RS26120	COG2814	Major facilitator Superfamily
E1A90_RS26140	COG1418	mRNA catabolic process
E1A90_RS26155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
E1A90_RS26160	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
E1A90_RS26190	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
E1A90_RS26195	COG1286	toxin biosynthetic process
E1A90_RS26200	COG1796	DNA polymerase
E1A90_RS26200	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
E1A90_RS26205	COG1193	negative regulation of DNA recombination
E1A90_RS26215	COG1114	Component of the transport system for branched-chain amino acids
E1A90_RS26220	COG5386	Cell surface protein
E1A90_RS26245	COG1120	ATPase activity
E1A90_RS26250	COG4509	Sortase family
E1A90_RS26255	COG2329	Antibiotic biosynthesis monooxygenase
E1A90_RS26265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
E1A90_RS26270	COG4895	conserved protein (DUF2196)
E1A90_RS26275	COG0745	RESPONSE REGULATOR receiver
E1A90_RS26280	COG2205	protein histidine kinase activity
E1A90_RS26285	COG1131	(ABC) transporter
E1A90_RS26305	COG2318	DinB family
E1A90_RS26330	COG1309	transcriptional regulator
E1A90_RS26335	COG1024	Enoyl-CoA hydratase
E1A90_RS26340	COG2086	electron transfer activity
E1A90_RS26345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
E1A90_RS26350	COG3118	belongs to the thioredoxin family
E1A90_RS26360	COG1719	4-vinyl reductase, 4VR
E1A90_RS26365	COG2009	succinate dehydrogenase
E1A90_RS26370	COG1053	succinate dehydrogenase
E1A90_RS26375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
E1A90_RS26380	COG0824	Thioesterase
E1A90_RS26385	COG1876	peptidase activity
E1A90_RS26395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
E1A90_RS26405	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
E1A90_RS26410	COG4152	abc transporter atp-binding protein
E1A90_RS26415	COG1668	transmembrane transport
E1A90_RS26420	COG1959	2 iron, 2 sulfur cluster binding
E1A90_RS26430	COG0697	spore germination
E1A90_RS26435	COG1396	sequence-specific DNA binding
E1A90_RS26440	COG1983	PspC domain protein
E1A90_RS26445	COG0402	S-adenosylhomocysteine deaminase activity
E1A90_RS26455	COG2197	response regulator
E1A90_RS26465	COG1309	transcriptional regulator
E1A90_RS26475	COG0477	Major facilitator Superfamily
E1A90_RS26485	COG5401	PFAM Sporulation and spore germination
E1A90_RS26490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
E1A90_RS26500	COG0622	Phosphoesterase
E1A90_RS26530	COG0544	peptidyl-prolyl cis-trans isomerase activity
E1A90_RS26540	COG0470	DNA polymerase III
E1A90_RS26540	COG1067	ATP-dependent peptidase activity
E1A90_RS26550	COG0218	Necessary for normal cell division and for the maintenance of normal septation
E1A90_RS26555	COG1764	response to oxidative stress
E1A90_RS26560	COG1846	Transcriptional regulator
E1A90_RS26565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
E1A90_RS26570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
E1A90_RS26575	COG0181	hydroxymethylbilane synthase activity
E1A90_RS26585	COG0113	porphobilinogen synthase activity
E1A90_RS26590	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
E1A90_RS26595	COG1388	LysM domain
E1A90_RS26605	COG0525	valine-tRNA ligase activity
E1A90_RS26610	COG0285	dihydrofolate synthase activity
E1A90_RS26625	COG0424	maF-like protein
E1A90_RS26630	COG2003	Belongs to the UPF0758 family
E1A90_RS26650	COG0850	regulation of cytokinetic process
E1A90_RS26655	COG2894	cell division
E1A90_RS26660	COG0739	heme binding
E1A90_RS26680	COG2868	ribosomal protein
E1A90_RS26690	COG3290	protein histidine kinase activity
E1A90_RS26695	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E1A90_RS26700	COG0745	RESPONSE REGULATOR receiver
E1A90_RS26705	COG5002	protein histidine kinase activity
E1A90_RS26710	COG1136	(ABC) transporter
E1A90_RS26720	COG0577	efflux transmembrane transporter activity
E1A90_RS26725	COG0077	Prephenate dehydratase
E1A90_RS26730	COG2258	MOSC domain
E1A90_RS26735	COG1827	regulation of RNA biosynthetic process
E1A90_RS26740	COG1104	cysteine desulfurase activity
E1A90_RS26750	COG0157	Belongs to the NadC ModD family
E1A90_RS26755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
E1A90_RS26785	COG0632	four-way junction helicase activity
E1A90_RS26790	COG2255	four-way junction helicase activity
E1A90_RS26800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
E1A90_RS26805	COG0343	queuine tRNA-ribosyltransferase activity
E1A90_RS26825	COG2244	polysaccharide biosynthetic process
E1A90_RS26835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1A90_RS26835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
E1A90_RS26845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
E1A90_RS26850	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
E1A90_RS26850	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
E1A90_RS26855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
E1A90_RS26860	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
E1A90_RS26865	COG1490	D-aminoacyl-tRNA deacylase activity
E1A90_RS26875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
E1A90_RS26880	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
E1A90_RS26890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
E1A90_RS26895	COG1959	2 iron, 2 sulfur cluster binding
E1A90_RS26900	COG1104	cysteine desulfurase activity
E1A90_RS26905	COG0482	sulfurtransferase activity
E1A90_RS26935	COG0628	permease
E1A90_RS26945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
E1A90_RS26950	COG4472	Bacterial protein of unknown function (DUF965)
E1A90_RS26955	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
E1A90_RS26965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
E1A90_RS26970	COG4122	O-methyltransferase activity
E1A90_RS26975	COG0826	peptidase U32
E1A90_RS26980	COG0826	peptidase U32
E1A90_RS26985	COG0572	uridine kinase
E1A90_RS26990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
E1A90_RS26995	COG0768	penicillin binding
E1A90_RS27010	COG2226	methyltransferase
E1A90_RS27015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
E1A90_RS27025	COG0626	cystathionine gamma-synthase activity
E1A90_RS27050	COG1454	alcohol dehydrogenase
E1A90_RS27050	COG1012	belongs to the aldehyde dehydrogenase family
E1A90_RS27060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
E1A90_RS27100	COG2259	Doxx family
E1A90_RS27105	COG2514	catechol 2,3-dioxygenase activity
E1A90_RS27115	COG3186	Phenylalanine-4-hydroxylase
E1A90_RS27120	COG1404	Belongs to the peptidase S8 family
E1A90_RS27155	COG2267	carboxylic ester hydrolase activity
E1A90_RS27165	COG1785	Belongs to the alkaline phosphatase family
E1A90_RS27175	COG2357	RelA SpoT domain protein
E1A90_RS27190	COG0688	phosphatidylethanolamine metabolic process
E1A90_RS27200	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
E1A90_RS27205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
E1A90_RS27210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
E1A90_RS27215	COG1534	Rna-binding protein
E1A90_RS27220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
E1A90_RS27225	COG1713	HD superfamily hydrolase involved in NAD metabolism
E1A90_RS27230	COG0799	negative regulation of ribosome biogenesis
E1A90_RS27240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
E1A90_RS27250	COG2131	deaminase
E1A90_RS27255	COG2333	competence protein COMEC
E1A90_RS27255	COG0658	competence protein
E1A90_RS27270	COG0268	Binds directly to 16S ribosomal RNA
E1A90_RS27275	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
E1A90_RS27285	COG0481	GTPase activity
E1A90_RS27290	COG1733	regulation of RNA biosynthetic process
E1A90_RS27295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
E1A90_RS27300	COG1420	regulation of RNA biosynthetic process
E1A90_RS27310	COG0443	Heat shock 70 kDa protein
E1A90_RS27325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
E1A90_RS27340	COG0828	Belongs to the bacterial ribosomal protein bS21 family
E1A90_RS27345	COG1610	YqeY-like protein
E1A90_RS27360	COG1702	phosphate starvation-inducible protein PhoH
E1A90_RS27370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
E1A90_RS27375	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
E1A90_RS27380	COG0295	cytidine deaminase activity
E1A90_RS27385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
E1A90_RS27395	COG1381	Involved in DNA repair and RecF pathway recombination
E1A90_RS27400	COG0517	IMP dehydrogenase activity
E1A90_RS27405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
E1A90_RS27415	COG0358	DNA primase activity
E1A90_RS27420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
E1A90_RS27425	COG2010	Cytochrome c
E1A90_RS27430	COG2384	SAM-dependent methyltransferase
E1A90_RS27435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
E1A90_RS27455	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
E1A90_RS27465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
E1A90_RS27480	COG0735	belongs to the Fur family
E1A90_RS27485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
E1A90_RS27505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
E1A90_RS27520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
E1A90_RS27525	COG0573	inorganic phosphate transmembrane transporter activity
E1A90_RS27530	COG0581	inorganic phosphate transmembrane transporter activity
E1A90_RS27540	COG0704	Plays a role in the regulation of phosphate uptake
E1A90_RS27550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
E1A90_RS27555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
E1A90_RS27560	COG4483	Protein conserved in bacteria
E1A90_RS27565	COG1940	carbohydrate kinase activity
E1A90_RS27575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS27595	COG0626	cystathionine gamma-synthase activity
E1A90_RS27600	COG0626	cystathionine gamma-synthase activity
E1A90_RS27605	COG0646	methionine synthase
E1A90_RS27605	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
E1A90_RS27610	COG1410	methionine synthase
E1A90_RS27610	COG0646	methionine synthase
E1A90_RS27665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
E1A90_RS27670	COG1459	type II secretion system
E1A90_RS27680	COG4970	Tfp pilus assembly protein FimT
E1A90_RS27705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
E1A90_RS27735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
E1A90_RS27740	COG0404	The glycine cleavage system catalyzes the degradation of glycine
E1A90_RS27745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E1A90_RS27750	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E1A90_RS27765	COG1725	Transcriptional regulator
E1A90_RS27800	COG2076	Multidrug Resistance protein
E1A90_RS27805	COG2076	Multidrug Resistance protein
E1A90_RS27815	COG1609	Transcriptional regulator
E1A90_RS27860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
E1A90_RS27870	COG3872	metal-dependent enzyme
E1A90_RS27880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
E1A90_RS27885	COG0006	proline dipeptidase activity
E1A90_RS27890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
E1A90_RS27910	COG3854	ATPases associated with a variety of cellular activities
E1A90_RS27955	COG0511	ligase activity, forming carbon-carbon bonds
E1A90_RS27960	COG0439	Biotin carboxylase
E1A90_RS27965	COG1302	Protein conserved in bacteria
E1A90_RS27970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E1A90_RS27975	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
E1A90_RS27980	COG1570	exodeoxyribonuclease VII activity
E1A90_RS27985	COG1722	exodeoxyribonuclease VII activity
E1A90_RS28000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
E1A90_RS28005	COG1438	arginine binding
E1A90_RS28010	COG0497	DNA recombination
E1A90_RS28015	COG0750	zinc metalloprotease
E1A90_RS28025	COG0745	RESPONSE REGULATOR receiver
E1A90_RS28060	COG3093	addiction module antidote protein HigA
E1A90_RS28065	COG0584	glycerophosphoryl diester phosphodiesterase
E1A90_RS28085	COG0280	phosphate acetyltransferase
E1A90_RS28095	COG3426	butyrate kinase activity
E1A90_RS28100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
E1A90_RS28105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E1A90_RS28110	COG0022	dehydrogenase e1 component
E1A90_RS28115	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1A90_RS28130	COG2323	membrane
E1A90_RS28135	COG2816	NAD+ diphosphatase activity
E1A90_RS28150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
E1A90_RS28155	COG0765	amino acid transport
E1A90_RS28165	COG4129	membrane
E1A90_RS28170	COG1376	ErfK ybiS ycfS ynhG family protein
E1A90_RS28180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
E1A90_RS28185	COG2195	Cleaves the N-terminal amino acid of tripeptides
E1A90_RS28210	COG1234	tRNA 3'-trailer cleavage
E1A90_RS28220	COG1760	l-serine dehydratase
E1A90_RS28225	COG1760	l-serine dehydratase
E1A90_RS28235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
E1A90_RS28240	COG0300	oxidoreductase activity
E1A90_RS28250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
E1A90_RS28260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
E1A90_RS28295	COG0737	Belongs to the 5'-nucleotidase family
E1A90_RS28315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
E1A90_RS28325	COG0156	8-amino-7-oxononanoate synthase activity
E1A90_RS28330	COG2226	methyltransferase
E1A90_RS28330	COG1073	alpha beta
E1A90_RS28335	COG4106	trans-aconitate 2-methyltransferase activity
E1A90_RS28340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
E1A90_RS28355	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E1A90_RS28355	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
E1A90_RS28360	COG0307	riboflavin synthase, alpha
E1A90_RS28365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1A90_RS28365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
E1A90_RS28380	COG1073	alpha beta
E1A90_RS28385	COG0456	acetyltransferase
E1A90_RS28395	COG1609	Transcriptional regulator
E1A90_RS28400	COG2056	Na+-H+ antiporter family
E1A90_RS28405	COG0596	Alpha beta hydrolase
E1A90_RS28415	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
E1A90_RS28430	COG0456	acetyltransferase
E1A90_RS28430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
E1A90_RS28440	COG0667	Aldo Keto reductase
E1A90_RS28460	COG1300	Membrane
E1A90_RS28465	COG0735	belongs to the Fur family
E1A90_RS28475	COG4974	Belongs to the 'phage' integrase family
E1A90_RS28485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
E1A90_RS28500	COG0598	Magnesium transport protein CorA
E1A90_RS28515	COG1846	Transcriptional regulator
E1A90_RS28540	COG1131	(ABC) transporter
E1A90_RS28545	COG1725	Transcriptional regulator
E1A90_RS28550	COG1686	Belongs to the peptidase S11 family
E1A90_RS28590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
E1A90_RS28605	COG0697	spore germination
E1A90_RS28610	COG0561	phosphatase activity
E1A90_RS28615	COG4086	secreted protein
E1A90_RS28620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
E1A90_RS28630	COG1547	Domain of unknown function (DUF309)
E1A90_RS28640	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
E1A90_RS28650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
E1A90_RS28665	COG0363	glucosamine-6-phosphate deaminase activity
E1A90_RS28670	COG2188	Transcriptional regulator
E1A90_RS28680	COG3711	transcriptional antiterminator
E1A90_RS28685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
E1A90_RS28685	COG2190	(PTS) system
E1A90_RS28685	COG1263	PTS System
E1A90_RS28710	COG0778	Nitroreductase
E1A90_RS28725	COG2084	Dehydrogenase
E1A90_RS28750	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
E1A90_RS28755	COG1850	ribulose-bisphosphate carboxylase activity
E1A90_RS28760	COG0436	Aminotransferase
E1A90_RS28770	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
E1A90_RS28775	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
E1A90_RS28785	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS28790	COG1695	Transcriptional regulator
E1A90_RS28825	COG0183	Belongs to the thiolase family
E1A90_RS28865	COG3842	ATPase activity
E1A90_RS28870	COG0366	Alpha amylase catalytic
E1A90_RS28880	COG2182	Extracellular solute-binding protein
E1A90_RS28885	COG1175	transmembrane transport
E1A90_RS28890	COG3833	ABC-type maltose transport systems, permease component
E1A90_RS28895	COG1609	Transcriptional regulator
E1A90_RS28900	COG0436	Aminotransferase
E1A90_RS28920	COG3209	COG3209 Rhs family protein
E1A90_RS28930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
E1A90_RS28940	COG2814	Major facilitator Superfamily
E1A90_RS28985	COG1408	metallophosphoesterase
E1A90_RS28990	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS28995	COG2200	EAL domain
E1A90_RS29010	COG4703	Protein of unknown function (DUF1797)
E1A90_RS29020	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
E1A90_RS29030	COG0517	IMP dehydrogenase activity
E1A90_RS29035	COG0583	DNA-binding transcription factor activity
E1A90_RS29040	COG2171	N-acyltransferase activity
E1A90_RS29045	COG1473	amidohydrolase
E1A90_RS29055	COG0569	domain protein
E1A90_RS29060	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
E1A90_RS29065	COG5503	Protein of unknown function (DUF1447)
E1A90_RS29075	COG0561	phosphatase activity
E1A90_RS29090	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
E1A90_RS29095	COG0022	dehydrogenase e1 component
E1A90_RS29100	COG0508	dehydrogenase complex catalyzes the overall conversion of
E1A90_RS29145	COG1982	Orn Lys Arg decarboxylase major
E1A90_RS29155	COG4493	Belongs to the UPF0637 family
E1A90_RS29165	COG0483	inositol monophosphate 1-phosphatase activity
E1A90_RS29175	COG1217	gtp-binding protein TYPA
E1A90_RS29190	COG4896	Protein conserved in bacteria
E1A90_RS29200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
E1A90_RS29205	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
E1A90_RS29210	COG4838	Belongs to the UPF0358 family
E1A90_RS29230	COG1612	heme a metabolic process
E1A90_RS29235	COG0109	protoheme IX farnesyltransferase activity
E1A90_RS29260	COG3336	cytochrome c oxidase
E1A90_RS29270	COG2340	Cysteine-rich secretory protein family
E1A90_RS29285	COG0406	alpha-ribazole phosphatase activity
E1A90_RS29290	COG3679	Belongs to the UPF0342 family
E1A90_RS29295	COG4471	UPF0298 protein
E1A90_RS29310	COG0742	ribosomal rna small subunit methyltransferase
E1A90_RS29315	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
E1A90_RS29320	COG3314	Sporulation integral membrane protein YlbJ
E1A90_RS29325	COG1752	Esterase of the alpha-beta hydrolase superfamily
E1A90_RS29330	COG3480	Lon protease (S16) C-terminal proteolytic domain
E1A90_RS29335	COG1323	Belongs to the UPF0348 family
E1A90_RS29340	COG1399	metal-binding, possibly nucleic acid-binding protein
E1A90_RS29345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
E1A90_RS29355	COG0454	-acetyltransferase
E1A90_RS29360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
E1A90_RS29365	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
E1A90_RS29370	COG0275	rRNA processing
E1A90_RS29385	COG0768	penicillin binding
E1A90_RS29390	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
E1A90_RS29395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
E1A90_RS29400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
E1A90_RS29405	COG0772	Belongs to the SEDS family
E1A90_RS29420	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
E1A90_RS29425	COG0849	cell division
E1A90_RS29430	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
E1A90_RS29440	COG1191	sigma factor activity
E1A90_RS29445	COG1191	sigma factor activity
E1A90_RS29450	COG1873	PFAM PRC-barrel domain
E1A90_RS29460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
E1A90_RS29465	COG1799	cell septum assembly
E1A90_RS29470	COG0762	integral membrane protein
E1A90_RS29475	COG2302	S4 RNA-binding domain
E1A90_RS29480	COG3599	regulation of cell shape
E1A90_RS29485	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
E1A90_RS29495	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
E1A90_RS29500	COG0564	pseudouridine synthase activity
E1A90_RS29505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
E1A90_RS29515	COG0540	Belongs to the ATCase OTCase family
E1A90_RS29520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
E1A90_RS29535	COG0543	2 iron, 2 sulfur cluster binding
E1A90_RS29560	COG3069	C4-dicarboxylate transmembrane transporter activity
E1A90_RS29600	COG1561	YicC-like family, N-terminal region
E1A90_RS29615	COG1758	RNA polymerase activity
E1A90_RS29620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E1A90_RS29625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
E1A90_RS29630	COG0242	peptide deformylase activity
E1A90_RS29635	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
E1A90_RS29640	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
E1A90_RS29640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
E1A90_RS29645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
E1A90_RS29650	COG0631	protein serine/threonine phosphatase activity
E1A90_RS29655	COG0515	serine threonine protein kinase
E1A90_RS29655	COG2815	serine threonine protein kinase
E1A90_RS29665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
E1A90_RS29685	COG1302	Protein conserved in bacteria
E1A90_RS29700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
E1A90_RS29705	COG2050	protein possibly involved in aromatic compounds catabolism
E1A90_RS29705	COG1349	DNA-binding transcription factor activity
E1A90_RS29710	COG0416	fatty acid biosynthetic process
E1A90_RS29715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
E1A90_RS29720	COG1028	Short-chain dehydrogenase reductase Sdr
E1A90_RS29725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
E1A90_RS29735	COG1196	nuclear chromosome segregation
E1A90_RS29740	COG0552	protein localization to endoplasmic reticulum
E1A90_RS29745	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
E1A90_RS29750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
E1A90_RS29760	COG1837	Belongs to the UPF0109 family
E1A90_RS29765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
E1A90_RS29770	COG0336	Belongs to the RNA methyltransferase TrmD family
E1A90_RS29775	COG0335	large ribosomal subunit rRNA binding
E1A90_RS29790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
E1A90_RS29795	COG0045	succinate-CoA ligase (ADP-forming) activity
E1A90_RS29800	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
E1A90_RS29805	COG0758	DNA mediated transformation
E1A90_RS29810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
E1A90_RS29820	COG4974	Belongs to the 'phage' integrase family
E1A90_RS29835	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
E1A90_RS29840	COG0052	Belongs to the universal ribosomal protein uS2 family
E1A90_RS29845	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
E1A90_RS29850	COG0528	UMP kinase activity
E1A90_RS29855	COG0233	cytoplasmic translational termination
E1A90_RS29865	COG4589	Belongs to the CDS family
E1A90_RS29875	COG0750	zinc metalloprotease
E1A90_RS29880	COG0442	prolyl-tRNA aminoacylation
E1A90_RS29895	COG0195	Participates in both transcription termination and antitermination
E1A90_RS29905	COG1358	cellular component organization or biogenesis
E1A90_RS29915	COG1550	Protein conserved in bacteria
E1A90_RS29920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
E1A90_RS29940	COG1185	polyribonucleotide nucleotidyltransferase activity
E1A90_RS29945	COG0726	polysaccharide deacetylase
E1A90_RS29950	COG0612	Peptidase, M16
E1A90_RS29955	COG1873	PFAM PRC-barrel domain
E1A90_RS29960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
E1A90_RS29965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
E1A90_RS29970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
E1A90_RS29975	COG0527	aspartate kinase activity
E1A90_RS29990	COG0740	serine-type endopeptidase activity
E1A90_RS30005	COG2188	Transcriptional regulator
E1A90_RS30010	COG1744	ABC transporter substrate-binding protein PnrA-like
E1A90_RS30015	COG3845	ABC transporter
E1A90_RS30020	COG4603	Belongs to the binding-protein-dependent transport system permease family
E1A90_RS30025	COG1079	Belongs to the binding-protein-dependent transport system permease family
E1A90_RS30030	COG0612	Peptidase, M16
E1A90_RS30035	COG0612	Peptidase, M16
E1A90_RS30040	COG0300	oxidoreductase activity
E1A90_RS30055	COG1426	Protein conserved in bacteria
E1A90_RS30060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
E1A90_RS30065	COG1058	Belongs to the CinA family
E1A90_RS30065	COG1546	Belongs to the CinA family
E1A90_RS30070	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
E1A90_RS30075	COG1418	mRNA catabolic process
E1A90_RS30080	COG1692	metallophosphoesterase
E1A90_RS30085	COG2359	stage V sporulation protein S
E1A90_RS30095	COG0674	pyruvate-flavodoxin oxidoreductase activity
E1A90_RS30095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
E1A90_RS30100	COG1013	pyruvate-flavodoxin oxidoreductase activity
E1A90_RS30105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
E1A90_RS30110	COG4550	Control of competence regulator ComK, YlbF/YmcA
E1A90_RS30120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
E1A90_RS30140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
E1A90_RS30155	COG3773	Cell wall hydrolase
E1A90_RS30165	COG2723	6-phospho-beta-galactosidase activity
E1A90_RS30170	COG2188	Transcriptional regulator
E1A90_RS30185	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
E1A90_RS30190	COG0596	Alpha beta hydrolase
E1A90_RS30195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
E1A90_RS30205	COG1346	cytolysis