locus-tag class description BWEI_RS00050 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BWEI_RS00090 ENOG4107SWG transcriptional regulator MERR family BWEI_RS00105 ENOG4105VEQ Cold shock protein BWEI_RS00115 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BWEI_RS00120 ENOG4105E4F Isochorismate synthase BWEI_RS00130 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BWEI_RS00135 ENOG4108IPT Naphthoate synthase BWEI_RS00145 ENOG4105DTQ mandelate racemase muconate lactonizing BWEI_RS00165 ENOG41069H0 dihydroorotase EC 3.5.2.3 BWEI_RS00190 ENOG4105C6Z Gluconate BWEI_RS00230 ENOG41082BM Transcriptional regulator, arsr family BWEI_RS00245 ENOG4105CJ1 ABC, transporter BWEI_RS00255 ENOG41086D8 Transcriptional regulator BWEI_RS00260 ENOG4105C19 ABC transporter BWEI_RS00280 ENOG4107ZTW SNARE associated Golgi BWEI_RS00320 ENOG4109050 May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG) BWEI_RS00325 ENOG4108UGV hypoxanthine phosphoribosyltransferase BWEI_RS00350 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS00355 ENOG4105BZU Histidine kinase BWEI_RS00360 ENOG4105N67 Proton-coupled thiamine transporter YuaJ BWEI_RS00385 ENOG41087YS Phage shock protein A BWEI_RS00425 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BWEI_RS00430 ENOG4105C4M (Ubiquinol oxidase) subunit I BWEI_RS00435 ENOG4108V2W Carbonate dehydratase BWEI_RS00460 ENOG41080TC multidrug resistance protein BWEI_RS00505 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BWEI_RS00520 ENOG4105EFP binding-protein-dependent transport systems inner membrane Component BWEI_RS00530 ENOG4105D2X ABC transporter substrate-binding protein BWEI_RS00555 ENOG4107T7U Sulfatase BWEI_RS00560 ENOG4107S9D Alpha beta hydrolase BWEI_RS00565 ENOG4105CH6 catalase BWEI_RS00570 ENOG4105BZU Histidine kinase BWEI_RS00575 ENOG4105BZU Histidine kinase BWEI_RS00635 ENOG4105EPU Molybdenum cofactor synthesis domain protein BWEI_RS00645 ENOG4105BZF Glycosyl transferase (Group 1 BWEI_RS00650 ENOG4105YVM Phosphoesterase, PA-phosphatase related BWEI_RS00655 ENOG4108Z0R Transferase BWEI_RS00660 ENOG4105E8V Alpha Beta Hydrolase Fold protein BWEI_RS00685 ENOG4105DA5 (ABC) transporter BWEI_RS00695 ENOG4105N5T Radical SAM Protein BWEI_RS00715 ENOG4105C19 ABC transporter BWEI_RS00730 ENOG4105NCW Trka-c domain protein BWEI_RS00735 ENOG4107S91 Sodium hydrogen exchanger BWEI_RS00740 ENOG410605W Major Facilitator BWEI_RS00775 ENOG4108B31 Spore germination protein BWEI_RS00785 ENOG4105DWV Homoserine O-trans-acetylase BWEI_RS00795 ENOG41085GJ domain protein BWEI_RS00820 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BWEI_RS00825 ENOG4105D06 uba thif-type nad fad binding protein BWEI_RS00835 ENOG4105CVM Molybdenum cofactor synthesis domain protein BWEI_RS00840 ENOG4108129 molybdopterin-guanine dinucleotide biosynthesis protein BWEI_RS00845 ENOG4108ZAF Molybdopterin BWEI_RS00865 ENOG4107EXU Short-chain dehydrogenase reductase Sdr BWEI_RS00870 ENOG4108VJ1 Transcriptional regulator (CarD family BWEI_RS00905 ENOG4105CBX hi0933 family BWEI_RS00920 ENOG4105YW5 deoR family transcriptional regulator BWEI_RS00925 ENOG4107QSE Dipeptidase BWEI_RS00935 ENOG4108IUM Glycogen debranching enzyme BWEI_RS00940 ENOG4108V15 phosphotransferase enzyme family BWEI_RS00955 ENOG4105C8F Beta-lactamase domain protein BWEI_RS00985 ENOG4108VDD TRNA binding domain protein BWEI_RS00995 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BWEI_RS01020 ENOG4105K7K Transcriptional regulator BWEI_RS01040 ENOG4105C88 aminopeptidase BWEI_RS01065 ENOG4105ETE Transcriptional regulator (LacI family BWEI_RS01085 ENOG4105EP9 oxidoreductase BWEI_RS01090 ENOG4107SNB ankyrin repeat protein YahD BWEI_RS01100 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BWEI_RS01115 ENOG4105DGU Histone deacetylase BWEI_RS01120 ENOG4105W87 Cbs domain BWEI_RS01125 ENOG4105F1V Acetoin utilization protein BWEI_RS01135 ENOG4108UW5 maltose o-acetyltransferase BWEI_RS01145 ENOG4105EMN RNA polymerase sigma factor BWEI_RS01175 ENOG4105D7V transposase BWEI_RS01180 ENOG4105C28 cystathionine BWEI_RS01190 ENOG4105U5Y Transcriptional regulator BWEI_RS01220 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BWEI_RS01230 ENOG4105EFZ amidohydrolase BWEI_RS01245 ENOG4105KBJ sporulation protein ytfj BWEI_RS01250 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BWEI_RS01280 ENOG4108JYZ YitT family BWEI_RS01320 ENOG4107YZX Universal stress protein BWEI_RS01340 ENOG4105VZ8 Transcriptional regulator BWEI_RS01350 ENOG41082W1 Cupin 2, conserved barrel domain protein BWEI_RS01385 ENOG4105DC7 peptidase M24 BWEI_RS01410 ENOG4105SFS phosphoesterase RecJ domain protein BWEI_RS01420 ENOG4105VV2 BWEI_RS01425 ENOG4105C0B DNA polymerase III (alpha subunit) BWEI_RS01430 ENOG4105C6K Malic enzyme BWEI_RS01435 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS01460 ENOG4105FS0 cytoplasmic membrane protein BWEI_RS01465 ENOG4108REF Sporulation integral membrane protein ytvi BWEI_RS01475 ENOG4105BZN citrate synthase BWEI_RS01480 ENOG4108HMX isocitrate dehydrogenase (NADP) BWEI_RS01500 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BWEI_RS01505 ENOG4105BZU Histidine kinase BWEI_RS01510 ENOG4105C2M dna polymerase I BWEI_RS01525 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BWEI_RS01530 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BWEI_RS01555 ENOG4108TDW sporulation protein YtxC BWEI_RS01560 ENOG4105C22 threonyL-tRNA synthetase BWEI_RS01585 ENOG4105CN9 Peptidase m42 family protein BWEI_RS01590 ENOG4108JGH Tetr family transcriptional regulator BWEI_RS01595 ENOG4105CW7 secretion protein, HlyD family BWEI_RS01600 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS01640 ENOG4108RWN rrna methyltransferase BWEI_RS01655 ENOG4105C5S asparaginyl-tRNA synthetase BWEI_RS01680 ENOG4105DCG PHP domain protein BWEI_RS01690 ENOG4105FE9 pseudouridine synthase BWEI_RS01700 ENOG4105SGM Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e. mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF. Hemin- free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity) BWEI_RS01705 ENOG4106ST0 Transfers its hemin to hemin-free IsdC (apo-IsdC) directly probably through the activation of the holo-IsdA-apo-IsdC complex and driven by the higher affinity of apo-IsdC for the cofactor. The reaction is reversible (By similarity). Binds transferrin, lactoferrin, heme, hemoglobin, hemin, fetuin, asialofetuin and protein A. Also binds fibronectin and chains B- beta and gamma of fibrinogen, promoting clumping of S.aureus with fibrinogen. Was also shown to adhere to plastic (By similarity). Inactivation of isdA leads to a decrease both in the amount of heme-iron associated with S.aureus cells and the amount of heme- iron that enters the staphylococcal cytoplasm. This suggests that IsdA could play a role in the removal of heme from hemoglobin. It was also demonstrated that the IsdA-mediated iron-acquisition system from transferrin could play only an ancillary role in the iron uptake whereas the siderophore-mediated iron-acquisition system from transferrin seems to play an essential or dominant role. Overexpression of isdA enhances S.aureus growth and an isdA inactivation mutant shows a growth defect when grown in liquid medium containing heme as the sole iron source which suggests that IsdA may function as a cell surface reservoir for heme. Involved in adherence of S.aureus to human desquamated nasal epithelial cells and is required for nasal colonization. Protects S.aureus against the bactericidal protease activity of apolactoferrin in vitro and confers resistance to bovine lactoferricin. Also IsdA and or IsdB promote resistance to hydrogen peroxide and killing by neutrophils (By similarity) BWEI_RS01720 ENOG4105E0A ABC, transporter BWEI_RS01725 ENOG4105KFN sortase, SrtB family BWEI_RS01735 ENOG4105DR4 Methyltransferase BWEI_RS01745 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BWEI_RS01785 ENOG4105S6R Iron-hydroxamate transporter permease subunit BWEI_RS01790 ENOG4105J76 Periplasmic binding protein BWEI_RS01800 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS01805 ENOG4107Z3H Transcriptional regulator, TetR family BWEI_RS01810 ENOG41060WC Enoyl-CoA hydratase BWEI_RS01815 ENOG4105BZJ Electron transfer flavoprotein BWEI_RS01820 ENOG4105C10 Electron transfer flavoprotein BWEI_RS01825 ENOG4105K63 Thioredoxin BWEI_RS01840 ENOG4108NU2 Succinate dehydrogenase cytochrome b558 subunit BWEI_RS01850 ENOG4105E33 succinate dehydrogenase BWEI_RS01860 ENOG4108VXD carboxy-peptidase BWEI_RS01865 ENOG4105E14 MotA TolQ exbB proton channel BWEI_RS01870 ENOG4105ER2 Ompa motb domain protein BWEI_RS01875 ENOG4105CUR 5'-nucleotidase, lipoprotein e(p4) family BWEI_RS01880 ENOG4108IUX (ABC) transporter BWEI_RS01885 ENOG4105RHA ABC transporter, permease BWEI_RS01890 ENOG4108Z40 Transcriptional regulator BWEI_RS01895 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BWEI_RS01905 ENOG4108JCI Transcriptional regulator BWEI_RS01910 ENOG41067S9 phage shock protein C, PspC BWEI_RS01915 ENOG4105DZC cytosine deaminase BWEI_RS01925 ENOG4105PFC Transcriptional regulator BWEI_RS01935 ENOG4108XJQ germination protein BWEI_RS01950 ENOG4105M59 Phosphodiesterase, mj0936 family BWEI_RS01965 ENOG4108QCI YvbH-like oligomerisation region BWEI_RS01985 ENOG4108IUQ atp-dependent protease BWEI_RS02005 ENOG4105K56 Transcriptional regulator BWEI_RS02030 ENOG4105D52 delta-aminolevulinic acid dehydratase BWEI_RS02040 ENOG41068KH stage VI sporulation protein D BWEI_RS02050 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BWEI_RS02055 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BWEI_RS02075 ENOG4107Y5K Resolvase BWEI_RS02115 ENOG4106CVF DNA replication protein BWEI_RS02195 ENOG4105CAR Terminase, large subunit BWEI_RS02205 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BWEI_RS02305 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BWEI_RS02335 ENOG4105DFF Rod shape-determining protein mreb BWEI_RS02355 ENOG4107QMS site-determining protein BWEI_RS02370 ENOG4105C03 ribonuclease BWEI_RS02380 ENOG4105X36 (ribosomal) protein BWEI_RS02405 ENOG4105EWM Histidine kinase BWEI_RS02425 ENOG4105CQC Prephenate dehydratase BWEI_RS02430 ENOG4108RPX mosc domain containing protein BWEI_RS02445 ENOG4108IYU L-aspartate oxidase BWEI_RS02450 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BWEI_RS02480 ENOG4108HUF Transporter BWEI_RS02495 ENOG41061AI Protein of unknown function (DUF2905) BWEI_RS02510 ENOG4105VIE preprotein translocase, subunit YajC BWEI_RS02520 ENOG4108QG2 Membrane BWEI_RS02525 ENOG4105CKP Polysaccharide Biosynthesis Protein BWEI_RS02535 ENOG4105C3D Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BWEI_RS02540 ENOG41076HS cation diffusion facilitator family transporter BWEI_RS02545 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BWEI_RS02555 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BWEI_RS02570 ENOG4105CUT histidyl-tRNA synthetase BWEI_RS02580 ENOG4105CUZ uba thif-type nad fad binding protein BWEI_RS02585 ENOG4108VCI transcription factor, rsfa family BWEI_RS02590 ENOG4105D1H recombination factor protein RarA BWEI_RS02600 ENOG4105C3J Cysteine desulfurase BWEI_RS02615 ENOG4105C7H Helicase, RecD TraA family BWEI_RS02620 ENOG41060CR BWEI_RS02635 ENOG4105C02 permease BWEI_RS02665 ENOG4105HHA aminodeoxychorismate lyase BWEI_RS02675 ENOG4105XYU peptidase (U32 family) BWEI_RS02680 ENOG4105CFP Peptidase U32 BWEI_RS02690 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BWEI_RS02695 ENOG4107XRG penicillin-binding protein BWEI_RS02725 ENOG4105C28 cystathionine BWEI_RS02730 ENOG4105C0A alcohol dehydrogenase BWEI_RS02740 ENOG4108V5C ABC transporter BWEI_RS02745 ENOG4105S6R Iron-hydroxamate transporter permease subunit BWEI_RS02785 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS02790 ENOG4105KZX Pterin carbinolamine dehydratase BWEI_RS02795 ENOG4105MIR Phenylalanine 4-monooxygenase BWEI_RS02800 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BWEI_RS02835 ENOG4108MUZ hydrolase BWEI_RS02845 ENOG4105G6Z alkaline phosphatase BWEI_RS02865 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS02880 ENOG4108WJV had superfamily (subfamily IIIa) phosphatase BWEI_RS02885 ENOG4105CQW ribosome biogenesis GTPase YqeH BWEI_RS02895 ENOG410812S Rna-binding protein BWEI_RS02905 ENOG4108WF2 Metal Dependent Phosphohydrolase BWEI_RS02915 ENOG4105DXX methyltransferase BWEI_RS02925 ENOG4105KQC Competence protein BWEI_RS02930 ENOG4108UK2 deaminase BWEI_RS02935 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 BWEI_RS02945 ENOG4105TQK DNA polymerase iii, delta' subunit BWEI_RS02970 ENOG4105KVH Transcriptional regulator BWEI_RS02975 ENOG4105CSA Coproporphyrinogen iii oxidase BWEI_RS03005 ENOG4107TVK Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BWEI_RS03010 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BWEI_RS03020 ENOG4105KTH gatB Yqey BWEI_RS03025 ENOG41068P3 sporulation protein YqfC BWEI_RS03035 ENOG4105C9A Phoh family BWEI_RS03040 ENOG4105CTJ Metal Dependent Phosphohydrolase BWEI_RS03050 ENOG4107YR5 Diacylglycerol kinase BWEI_RS03055 ENOG4105KG3 cytidine deaminase BWEI_RS03060 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BWEI_RS03080 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BWEI_RS03085 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS03100 ENOG4105EGD dinuclear metal center protein, YbgI family BWEI_RS03125 ENOG41069ZM Protein of unknown function (DUF2624) BWEI_RS03130 ENOG4108JYZ YitT family BWEI_RS03135 ENOG4105FDK ABC transporter BWEI_RS03145 ENOG4105N80 Ferric uptake regulator, Fur family BWEI_RS03170 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BWEI_RS03180 ENOG4107RF6 penicillin-binding protein BWEI_RS03185 ENOG4105PWN phosphate abc transporter BWEI_RS03190 ENOG4105C8U phosphate abc transporter BWEI_RS03195 ENOG4105E2Z phosphate ABC transporter (Permease BWEI_RS03200 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BWEI_RS03205 ENOG4108UTW Plays a role in the regulation of phosphate uptake BWEI_RS03220 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BWEI_RS03230 ENOG4105DKQ ROK family BWEI_RS03240 ENOG4105C5X domain protein BWEI_RS03255 ENOG4105C28 cystathionine BWEI_RS03260 ENOG4105C28 cystathionine BWEI_RS03270 ENOG4105C3R Methionine synthase BWEI_RS03385 ENOG4105C0D helicase BWEI_RS03415 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS03450 ENOG41080TC multidrug resistance protein BWEI_RS03475 ENOG4105WZW rhodanese family BWEI_RS03480 ENOG41082GG biotin lipoate A B protein ligase BWEI_RS03510 ENOG4107YBY Hydrolase BWEI_RS03520 ENOG4105CBJ Metal-dependent enzyme BWEI_RS03535 ENOG4105DC7 peptidase M24 BWEI_RS03560 ENOG4105CD2 stage iii sporulation protein aa BWEI_RS03565 ENOG4105KR5 Stage iii sporulation protein BWEI_RS03570 ENOG4108CQH stage III sporulation protein AC BWEI_RS03575 ENOG4105KQ4 Stage iii sporulation protein ad BWEI_RS03585 ENOG410644B Stage III sporulation protein af BWEI_RS03605 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BWEI_RS03610 ENOG4108ZSR alkaline shock protein BWEI_RS03635 ENOG4105CTB Polyprenyl synthetase BWEI_RS03645 ENOG4105DX0 Hemolysin A BWEI_RS03655 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BWEI_RS03660 ENOG4105S1Z Stage IV sporulation protein B BWEI_RS03665 ENOG4107QQR Sporulation BWEI_RS03680 ENOG4108IBT Inherit from COG: transposase BWEI_RS03715 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BWEI_RS03720 ENOG4106CCJ Protein of unknown function (DUF2627) BWEI_RS03725 ENOG4108JUB Transcriptional regulator BWEI_RS03735 ENOG4107RDP Dehydrogenase BWEI_RS03755 ENOG4105CPP Dehydrogenase, E1 component BWEI_RS03760 ENOG4105C7S Dehydrogenase BWEI_RS03770 ENOG4108QY0 Membrane BWEI_RS03775 ENOG4105E09 nadh pyrophosphatase BWEI_RS03785 ENOG4108HW3 (ABC) transporter BWEI_RS03790 ENOG4105E5Q amino acid AbC transporter BWEI_RS03795 ENOG4105CDA abc transporter atp-binding protein BWEI_RS03800 ENOG4108QEG Membrane BWEI_RS03805 ENOG4108VZI ErfK ybiS ycfS ynhG family protein BWEI_RS03815 ENOG4105D9U N-acetyltransferase BWEI_RS03820 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BWEI_RS03845 ENOG4108RDQ ABC transporter BWEI_RS03890 ENOG4105EJQ L-serine dehydratase BWEI_RS03895 ENOG4105II7 pyrroline-5-carboxylate reductase BWEI_RS03900 ENOG41069FQ Metallo-beta-lactamase superfamily BWEI_RS03905 ENOG4108IXY short-chain dehydrogenase reductase BWEI_RS03960 ENOG4105CGH 5'-nucleotidase BWEI_RS03965 ENOG4105DFD Na H antiporter BWEI_RS03975 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BWEI_RS03990 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BWEI_RS03995 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BWEI_RS04020 ENOG4108R6K riboflavin synthase, subunit alpha BWEI_RS04025 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BWEI_RS04045 ENOG4108YM7 Gcn5-related n-acetyltransferase BWEI_RS04050 ENOG4105ETE Transcriptional regulator (LacI family BWEI_RS04060 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BWEI_RS04080 ENOG4105RHY Pfam:UPF0157 BWEI_RS04090 ENOG4105CPC Aldo Keto reductase BWEI_RS04110 ENOG4105MZ9 stage II sporulation protein m BWEI_RS04115 ENOG4105I3K Ferric uptake regulator, Fur family BWEI_RS04125 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BWEI_RS04150 ENOG4105D7N magnesium and cobalt transport protein CorA BWEI_RS04185 ENOG4105DVE abc transporter atp-binding protein BWEI_RS04190 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS04195 ENOG4105DZ1 carboxypeptidase BWEI_RS04200 ENOG41082AN stage II sporulation protein BWEI_RS04210 ENOG4105CT2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS04215 ENOG4105C8J )-transporter BWEI_RS04235 ENOG41090VF Stage v sporulation protein ac BWEI_RS04240 ENOG4105CZ3 stage V sporulation protein ad BWEI_RS04250 ENOG4105G6R Stage v sporulation protein ae BWEI_RS04260 ENOG4105J7I hydrolase BWEI_RS04265 ENOG4105PTM secreted protein BWEI_RS04270 ENOG4107ZE5 PPIases accelerate the folding of proteins BWEI_RS04300 ENOG4105CE4 GlcNAc 6-P deacetylase BWEI_RS04320 ENOG4105CID antiterminator BWEI_RS04335 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BWEI_RS04355 ENOG4105BZU Histidine kinase BWEI_RS04365 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BWEI_RS04405 ENOG4105CQP nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BWEI_RS04420 ENOG4105DTD Dehydrogenase BWEI_RS04425 ENOG4105K7K Transcriptional regulator BWEI_RS04455 ENOG4105CHU acetyl-coa acetyltransferase BWEI_RS04460 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BWEI_RS04505 ENOG4105CG3 alpha amylase, catalytic region BWEI_RS04515 ENOG4107FKK extracellular solute-binding protein family 1 BWEI_RS04525 ENOG4105EG2 ABC transporter, permease BWEI_RS04530 ENOG4105FKQ transcriptional regulator BWEI_RS04535 ENOG4105CHM Aminotransferase BWEI_RS04545 ENOG4108HGU Histidine kinase BWEI_RS04600 ENOG4105UIN BWEI_RS04610 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BWEI_RS04625 ENOG4105K6S Short-chain dehydrogenase reductase Sdr BWEI_RS04630 ENOG4105EPM Diguanylate phosphodiesterase BWEI_RS04645 ENOG4107IN1 Protein of unknown function (DUF1797) BWEI_RS04650 ENOG4108XRC Protein of unknown function (DUF458) BWEI_RS04685 ENOG4107ZYR domain protein BWEI_RS04690 ENOG4105CN5 Metallo-Beta-Lactamase BWEI_RS04705 ENOG4108X4Q Hydrolase BWEI_RS04710 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BWEI_RS04725 ENOG4105CPP Dehydrogenase, E1 component BWEI_RS04730 ENOG4105C7S Dehydrogenase BWEI_RS04775 ENOG4105CXN decarboxylase BWEI_RS04795 ENOG4105ECY inositol monophosphatase BWEI_RS04805 ENOG4105CI3 gtp-binding protein typa BWEI_RS04810 ENOG4105QA2 BWEI_RS04830 ENOG4108IAB Phoh family BWEI_RS04845 ENOG4105CNI cell division protein FtsW BWEI_RS04850 ENOG4108JIJ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity) BWEI_RS04895 ENOG4106UY4 Inherit from COG: Scp-like extracellular BWEI_RS04910 ENOG4107TB6 phosphoglycerate mutase BWEI_RS04930 ENOG4106H78 methyltransferase BWEI_RS04940 ENOG4105H20 Sporulation integral membrane protein YlbJ BWEI_RS04945 ENOG4105D78 K07001 NTE family protein BWEI_RS04950 ENOG41063PX domain protein BWEI_RS04960 ENOG4105KNH Nucleic acid-binding protein BWEI_RS05000 ENOG4105CJN penicillin-binding protein BWEI_RS05005 ENOG4105CJN penicillin-binding protein BWEI_RS05010 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BWEI_RS05025 ENOG4105CNI cell division protein FtsW BWEI_RS05040 ENOG4108W8M Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity) BWEI_RS05045 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BWEI_RS05050 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BWEI_RS05060 ENOG4105DAV Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS05070 ENOG4105WR5 sporulation protein, YlmC YmxH family BWEI_RS05075 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BWEI_RS05080 ENOG4105DFA alanine racemase domain protein BWEI_RS05090 ENOG41067XK integral membrane protein BWEI_RS05095 ENOG4105DBK s4 domain protein BWEI_RS05120 ENOG4105C34 Pseudouridine synthase BWEI_RS05200 ENOG4105DC7 peptidase M24 BWEI_RS05220 ENOG4105DSJ YicC domain protein BWEI_RS05240 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BWEI_RS05245 ENOG4105C25 Primosomal protein n' BWEI_RS05250 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BWEI_RS05260 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BWEI_RS05270 ENOG4108ZF3 Phosphatase BWEI_RS05275 ENOG4105D9P serine threonine protein kinase BWEI_RS05285 ENOG4105DJV ribulose-phosphate 3-epimerase BWEI_RS05290 ENOG4105FJ0 thiamine BWEI_RS05305 ENOG4108ZAA Alkaline-shock protein BWEI_RS05310 ENOG4105DP4 dak2 domain fusion protein ylov BWEI_RS05315 ENOG4105CB5 ATP-dependent DNA helicase recG BWEI_RS05330 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BWEI_RS05335 ENOG4105CHR reductase BWEI_RS05350 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) BWEI_RS05355 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BWEI_RS05375 ENOG4105VB6 UPF0109 protein BWEI_RS05400 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BWEI_RS05415 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BWEI_RS05420 ENOG4105C79 DNA protecting protein DprA BWEI_RS05425 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BWEI_RS05435 ENOG4108HE4 integrase family BWEI_RS05475 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BWEI_RS05480 ENOG4105KNE Phosphatidate cytidylyltransferase BWEI_RS05490 ENOG4105DZP Membrane-associated zinc metalloprotease BWEI_RS05500 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BWEI_RS05510 ENOG4105CHV Transcription elongation factor NusA BWEI_RS05515 ENOG4105VZN Nucleic-acid-binding protein implicated in transcription termination BWEI_RS05520 ENOG4105VHM ribosomal protein BWEI_RS05530 ENOG4105W7A Protein of unknown function (DUF503) BWEI_RS05545 ENOG4105DTN riboflavin biosynthesis protein ribF BWEI_RS05565 ENOG4105C1V Peptidase, M16 BWEI_RS05575 ENOG4105E35 Dipicolinate synthase subunit A BWEI_RS05580 ENOG4108S0H Dipicolinic acid synthetase, b subunit BWEI_RS05585 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BWEI_RS05595 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BWEI_RS05605 ENOG4105CVQ ATP-dependent Clp protease, proteolytic subunit BWEI_RS05615 ENOG4107QZI cell division protein FtsK BWEI_RS05620 ENOG4105FDP GntR family transcriptional regulator BWEI_RS05625 ENOG4105DIH basic membrane BWEI_RS05630 ENOG4108JQ9 ABC transporter BWEI_RS05635 ENOG4105UIB (ABC) transporter BWEI_RS05655 ENOG4108RKS Short-chain dehydrogenase reductase Sdr BWEI_RS05660 ENOG4105XZV Protein of unknown function (DUF3243) BWEI_RS05675 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BWEI_RS05695 ENOG4105D48 metallophosphoesterase BWEI_RS05700 ENOG4105MCT stage V sporulation protein S BWEI_RS05705 ENOG4108IGT Dipeptidase BWEI_RS05710 ENOG4105DI2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein BWEI_RS05715 ENOG4105DQU oxidoreductase, subunit beta BWEI_RS05745 ENOG4107QHE Choloylglycine hydrolase BWEI_RS05755 ENOG410890F Dynamin family BWEI_RS05760 ENOG4105E0M Sulfatase BWEI_RS05770 ENOG4105F0V Cell wall hydrolase BWEI_RS05780 ENOG4105CS2 ec 3.2.1.21 BWEI_RS05785 ENOG4108S3Y transcriptional regulator BWEI_RS05795 ENOG4107YEI lmbE family BWEI_RS05800 ENOG4107TTQ Alpha beta hydrolase fold BWEI_RS05815 ENOG41067MG lrgb family BWEI_RS05855 ENOG4105BZU Histidine kinase BWEI_RS05860 ENOG4105HB7 Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS05885 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BWEI_RS05890 ENOG4105D03 DNA-3-methyladenine glycosylase II BWEI_RS05895 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BWEI_RS05905 ENOG4105CGK Exodeoxyribonuclease III BWEI_RS05925 ENOG4105E0A ABC, transporter BWEI_RS05930 ENOG4105NIV Esterase BWEI_RS05950 ENOG4105VPX protein, conserved in bacteria BWEI_RS05955 ENOG410681U heavy metal transport detoxification protein BWEI_RS05960 ENOG4105C59 p-type ATPase BWEI_RS05970 ENOG4105K70 DNA-binding protein BWEI_RS05975 ENOG4105TMB Formate nitrite transporter BWEI_RS05995 ENOG4105C85 amino acid BWEI_RS06005 ENOG4108SJC Membrane BWEI_RS06010 ENOG4107QW4 alcohol dehydrogenase BWEI_RS06015 ENOG4105E98 transcriptional regulator DeoR family BWEI_RS06020 ENOG4105DE4 1-phosphofructokinase BWEI_RS06025 ENOG4105DM4 PTS System BWEI_RS06030 ENOG41069ER domain protein BWEI_RS06060 ENOG4106F1P AAA ATPase, central domain protein BWEI_RS06065 ENOG4105EN6 Membrane BWEI_RS06070 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BWEI_RS06075 ENOG4105CXI aluminum resistance protein BWEI_RS06080 ENOG4105KV4 Transcriptional regulator BWEI_RS06085 ENOG4105C5F glutamine synthetase BWEI_RS06090 ENOG4105K7K Transcriptional regulator BWEI_RS06110 ENOG4108SVB resolvase BWEI_RS06120 ENOG4105CGH 5'-nucleotidase BWEI_RS06125 ENOG4108HW3 (ABC) transporter BWEI_RS06160 ENOG4105BZ1 (ABC) transporter BWEI_RS06165 ENOG4105BZ1 (ABC) transporter BWEI_RS06185 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BWEI_RS06210 ENOG41067MG lrgb family BWEI_RS06220 ENOG4107RSM transcriptional regulator BWEI_RS06230 ENOG4105CJ1 ABC, transporter BWEI_RS06235 ENOG4108TU7 Inherit from COG: (ABC) transporter BWEI_RS06250 ENOG4107QIV Cytochrome c biogenesis protein BWEI_RS06280 ENOG4107UA9 Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity) BWEI_RS06305 ENOG4108903 Formimidoylglutamase BWEI_RS06310 ENOG4108VJ1 Transcriptional regulator (CarD family BWEI_RS06320 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BWEI_RS06325 ENOG4105CBC glutamate synthase BWEI_RS06330 ENOG4105CK7 Sodium proline symporter BWEI_RS06335 ENOG4105DA2 glyoxalase bleomycin resistance protein dioxygenase BWEI_RS06340 ENOG4105FBA Phospholipase Carboxylesterase BWEI_RS06350 ENOG4105BZU Histidine kinase BWEI_RS06360 ENOG4107AYK membrAne BWEI_RS06400 ENOG4108IMY Transcriptional regulator BWEI_RS06405 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS06410 ENOG4107ZYJ bioY protein BWEI_RS06415 ENOG4107F3J Amp-dependent synthetase and ligase BWEI_RS06435 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BWEI_RS06445 ENOG4105E5W Transporter BWEI_RS06475 ENOG4108I0Z Aconitate hydratase BWEI_RS06480 ENOG4105BZ1 (ABC) transporter BWEI_RS06495 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BWEI_RS06500 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BWEI_RS06520 ENOG4105W8X HesB YadR YfhF-family protein BWEI_RS06530 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BWEI_RS06535 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BWEI_RS06540 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS06545 ENOG4105C0H protease BWEI_RS06550 ENOG4105K4P CoA-binding domain protein BWEI_RS06555 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BWEI_RS06565 ENOG4105D9R oxidoreductase BWEI_RS06585 ENOG4105CIG ABC transporter BWEI_RS06600 ENOG4108KGH TRANSCRIPTIONal BWEI_RS06650 ENOG410696E Membrane BWEI_RS06655 ENOG4105FR1 rard protein BWEI_RS06665 ENOG4105EWU Squalene--hopene cyclase BWEI_RS06675 ENOG4105CHR reductase BWEI_RS06680 ENOG4105C26 Dehydrogenase BWEI_RS06690 ENOG4108IA2 Sodium pantothenate symporter BWEI_RS06705 ENOG4106IQC argininosuccinate lyase BWEI_RS06715 ENOG410904N short-chain dehydrogenase reductase BWEI_RS06735 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BWEI_RS06755 ENOG4105VEQ Cold shock protein BWEI_RS06770 ENOG4108R1P BWEI_RS06780 ENOG41073R8 VanW family BWEI_RS06785 ENOG4108HW4 amino acid AbC transporter BWEI_RS06795 ENOG4105EAB amino acid AbC transporter BWEI_RS06800 ENOG4108TKW Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS06810 ENOG4105KT7 mgtC SapB transporter BWEI_RS06840 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BWEI_RS06855 ENOG4105CQB FAD linked oxidase domain protein BWEI_RS06890 ENOG4105CIS alcohol dehydrogenase BWEI_RS06895 ENOG41082BM Transcriptional regulator, arsr family BWEI_RS06935 ENOG4105EGI Transcriptional regulator BWEI_RS06950 ENOG4108A04 Beta-lactamase BWEI_RS06965 ENOG4105FFC UPF0187 protein BWEI_RS06990 ENOG4105DPN Oligoendopeptidase f BWEI_RS06995 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BWEI_RS07000 ENOG4105E5K Alpha-amylase BWEI_RS07015 ENOG4105C98 muts2 protein BWEI_RS07030 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BWEI_RS07035 ENOG4107V2S Transcriptional regulator BWEI_RS07055 ENOG4105NX3 Membrane BWEI_RS07075 ENOG4107R3E Citrate transporter BWEI_RS07085 ENOG4108TN2 lmbE family BWEI_RS07095 ENOG4105MWK D-amino acid dehydrogenase, small subunit BWEI_RS07105 ENOG4105C3S Mate efflux family protein BWEI_RS07120 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BWEI_RS07145 ENOG4105CIS alcohol dehydrogenase BWEI_RS07185 ENOG4105H3G oxidoreductase BWEI_RS07195 ENOG4107R6D beta-lactam binding protein AmpH BWEI_RS07215 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BWEI_RS07240 ENOG4105C44 Serine transporter BWEI_RS07280 ENOG4105BZU Histidine kinase BWEI_RS07305 ENOG4105NA0 Transcriptional regulator BWEI_RS07345 ENOG4108VXD carboxy-peptidase BWEI_RS07390 ENOG4105KVH Transcriptional regulator BWEI_RS07395 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BWEI_RS07410 ENOG4105JAB phenazine biosynthesis protein, phzf family BWEI_RS07455 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BWEI_RS07470 ENOG4105CMG Carbohydrate kinase BWEI_RS07475 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BWEI_RS07480 ENOG4105XDF Protein of unknown function (DUF1272) BWEI_RS07485 ENOG4105DDN Pentapeptide repeat-containing protein BWEI_RS07515 ENOG4105FAW cDP-glucose 4,6-dehydratase BWEI_RS07520 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BWEI_RS07535 ENOG4105C37 (CBS) domain BWEI_RS07565 ENOG4105EV4 Multidrug resistance protein mdtH BWEI_RS07575 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BWEI_RS07585 ENOG4107BMA Transglycosylase associated protein BWEI_RS07605 ENOG4108UW5 maltose o-acetyltransferase BWEI_RS07610 ENOG4106UW1 Major Facilitator superfamily BWEI_RS07615 ENOG4105DKQ ROK family BWEI_RS07620 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS07700 ENOG4105KVH Transcriptional regulator BWEI_RS07705 ENOG4108RCM Nitroreductase BWEI_RS07710 ENOG4105G6Z alkaline phosphatase BWEI_RS07740 ENOG4108Z66 YbaK ebsC protein BWEI_RS07750 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BWEI_RS07755 ENOG4108K8S endonuclease I BWEI_RS07785 ENOG4108JJB ABC transporter BWEI_RS07825 ENOG4108X0B nad(p)h dehydrogenase (quinone) BWEI_RS07835 ENOG4105CRW Short chain fatty acid transporter BWEI_RS07840 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BWEI_RS07860 ENOG4107258 Transcriptional regulator BWEI_RS07915 ENOG4105ED2 Beta-lactamase BWEI_RS07950 ENOG4105IIU Aminopeptidase BWEI_RS08245 ENOG4105D7V transposase BWEI_RS08250 ENOG4105ETE Transcriptional regulator (LacI family BWEI_RS08255 ENOG4105IE8 Alpha-ketoglutarate permease BWEI_RS08260 ENOG4105CK5 oxidoreductase BWEI_RS08285 ENOG4105D2N Aldolase BWEI_RS08290 ENOG4105DH8 myo-inositol catabolism BWEI_RS08325 ENOG4105DYB Isoaspartyl dipeptidase BWEI_RS08345 ENOG4105VZ8 Transcriptional regulator BWEI_RS08365 ENOG4105W1Y Transcriptional regulator BWEI_RS08450 ENOG4105CZM Major Facilitator BWEI_RS08455 ENOG4107MII Sugar-specific transcriptional regulator TrmB BWEI_RS08470 ENOG4108ISG Major Facilitator BWEI_RS08480 ENOG4105PNM synthesis protein BWEI_RS08485 ENOG4108VXD carboxy-peptidase BWEI_RS08530 ENOG4108IG5 Transcriptional regulator BWEI_RS08560 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BWEI_RS08565 ENOG4108JQ1 Dehydrogenase BWEI_RS08585 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BWEI_RS08600 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BWEI_RS08615 ENOG4105BZU Histidine kinase BWEI_RS08640 ENOG4105I2S Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity) BWEI_RS08660 ENOG4105JQZ Methyltransferase BWEI_RS08680 ENOG4105E0Y RtcB Protein BWEI_RS08715 ENOG4105K6H D-cysteine desulfhydrase BWEI_RS08745 ENOG41062D9 Histidine kinase BWEI_RS08750 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS08780 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS08785 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BWEI_RS08790 ENOG4105DMQ Methyltransferase BWEI_RS08825 ENOG4108YXU transcriptional regulator AsnC family BWEI_RS08830 ENOG4105CHR reductase BWEI_RS08835 ENOG4108IG5 Transcriptional regulator BWEI_RS08840 ENOG4107P5I polyketide synthase BWEI_RS08850 ENOG41085FC arsR family transcriptional regulator BWEI_RS08855 ENOG4108YZ3 Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS08860 ENOG4105D6J arsenicaL-resistance protein BWEI_RS08880 ENOG4107ZQN disulfide bond BWEI_RS08885 ENOG4108KF3 Electron transport protein SCO1 SenC BWEI_RS08900 ENOG4105DIK (ABC) transporter BWEI_RS08905 ENOG4105CC5 ABC transporter BWEI_RS08910 ENOG4105DSE periplasmic solute binding protein BWEI_RS08930 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BWEI_RS08940 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS08945 ENOG4105BZU Histidine kinase BWEI_RS08950 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BWEI_RS08970 ENOG4105F6J Alpha beta hydrolase fold BWEI_RS08985 ENOG4105CJ1 ABC, transporter BWEI_RS09010 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BWEI_RS09025 ENOG4105FQP Beta-lactamase BWEI_RS09035 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BWEI_RS09045 ENOG4107R95 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BWEI_RS09075 ENOG4105DWD nucleoside recognition domain protein BWEI_RS09085 ENOG41082BM Transcriptional regulator, arsr family BWEI_RS09110 ENOG4105FDT acyl-CoA dehydrogenase BWEI_RS09120 ENOG4106N3A copper homeostasis protein cutc BWEI_RS09140 ENOG4107258 Transcriptional regulator BWEI_RS09145 ENOG4105P4J Allophanate hydrolase, subunit 1 BWEI_RS09175 ENOG4105DUX Transporter BWEI_RS09180 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BWEI_RS09185 ENOG4107RF6 penicillin-binding protein BWEI_RS09215 ENOG4105F1N DNA alkylation repair BWEI_RS09225 ENOG4108IQI permease BWEI_RS09235 ENOG410635A Membrane BWEI_RS09260 ENOG4105RHY Pfam:UPF0157 BWEI_RS09285 ENOG4105BZU Histidine kinase BWEI_RS09295 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS09330 ENOG41063TF transcriptional regulator (AraC BWEI_RS09380 ENOG4108PCN EamA-like transporter family BWEI_RS09395 ENOG4108XET gCN5-related N-acetyltransferase BWEI_RS09430 ENOG410811P TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS09450 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BWEI_RS09465 ENOG4105FS7 Transcriptional regulator BWEI_RS09470 ENOG4108TVJ Nitroreductase BWEI_RS09480 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BWEI_RS09520 ENOG4105CH6 catalase BWEI_RS09525 ENOG4105C8Y Acetylornithine aminotransferase BWEI_RS09530 ENOG4105CSH Transporter BWEI_RS09545 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BWEI_RS09570 ENOG41068WN BWEI_RS09610 ENOG4105VMP Transcriptional regulator BWEI_RS09620 ENOG4105ECK Fatty Acid Desaturase BWEI_RS09625 ENOG4105II7 pyrroline-5-carboxylate reductase BWEI_RS09650 ENOG41075H3 AraC family transcriptional regulator BWEI_RS09675 ENOG4105Z26 Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity) BWEI_RS09680 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS09695 ENOG4108I0C methyltransferase BWEI_RS09700 ENOG41061GT Aldolase BWEI_RS09715 ENOG4105DKT Transcriptional regulator BWEI_RS09720 ENOG4105C2J ABC transporter BWEI_RS09725 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BWEI_RS09735 ENOG4105D4B ABC, transporter BWEI_RS09750 ENOG4108JUB Transcriptional regulator BWEI_RS09760 ENOG4105E39 Enoyl-CoA hydratase BWEI_RS09765 ENOG4105CY2 Citrate transporter BWEI_RS09775 ENOG4108YYH Nadph-dependent fmn reductase BWEI_RS09785 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BWEI_RS09795 ENOG41069ER domain protein BWEI_RS09815 ENOG4105FFM Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity) BWEI_RS09835 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BWEI_RS09840 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BWEI_RS09875 ENOG41082JN Transcriptional regulator BWEI_RS09880 ENOG4105EYF MMPL domain protein BWEI_RS09915 ENOG4105C5H ABC transporter BWEI_RS09935 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS09995 ENOG4108AQF aminoglycoside N(3)-acetyltransferase BWEI_RS10025 ENOG4105C02 permease BWEI_RS10070 ENOG4105DVE abc transporter atp-binding protein BWEI_RS10095 ENOG4105CHM Aminotransferase BWEI_RS10130 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BWEI_RS10145 ENOG4107BMA Transglycosylase associated protein BWEI_RS10165 ENOG4106K7D Major facilitator family transporter BWEI_RS10170 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BWEI_RS10205 ENOG4105CHJ isochorismatase hydrolase BWEI_RS10230 ENOG4105EPR degv family BWEI_RS10245 ENOG4105DPN Oligoendopeptidase f BWEI_RS10250 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BWEI_RS10255 ENOG4107S75 HAD-superfamily hydrolase subfamily IA variant 3 BWEI_RS10275 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS10285 ENOG4105GYP Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity) BWEI_RS10325 ENOG4105CPC Aldo Keto reductase BWEI_RS10345 ENOG4105DTQ mandelate racemase muconate lactonizing BWEI_RS10360 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BWEI_RS10375 ENOG4107T5V SNARE associated Golgi BWEI_RS10405 ENOG4107KMQ bfd domain protein (2fe-2s)-binding domain protein BWEI_RS10415 ENOG41080HI glycine oxidase BWEI_RS10420 ENOG4105CTU Proline racemase BWEI_RS10425 ENOG4105CTU Proline racemase BWEI_RS10430 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BWEI_RS10435 ENOG4105C26 Dehydrogenase BWEI_RS10440 ENOG4105BZG amino acid carrier protein BWEI_RS10450 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BWEI_RS10470 ENOG4108M1A Chitin-binding protein BWEI_RS10515 ENOG4105C9U ATP-dependent DNA helicase RecQ BWEI_RS10530 ENOG4105EEM helicase BWEI_RS10545 ENOG4108Z7F N-acetyltransferase BWEI_RS10570 ENOG4105MSB protein, conserved in bacteria BWEI_RS10590 ENOG41087PP glycosyltransferase MGT family BWEI_RS10600 ENOG4108M1A Chitin-binding protein BWEI_RS10620 ENOG41082BV acetyltransferase BWEI_RS10650 ENOG4108IJ7 Glycine betaine BWEI_RS10655 ENOG4107SQ8 Glycine betaine BWEI_RS10690 ENOG4105RHY Pfam:UPF0157 BWEI_RS10695 ENOG4105E1F short-chain dehydrogenase reductase BWEI_RS10705 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BWEI_RS10725 ENOG41062ES Transcriptional regulator BWEI_RS10745 ENOG4105E98 transcriptional regulator DeoR family BWEI_RS10775 ENOG4107Z3H Transcriptional regulator, TetR family BWEI_RS10815 ENOG4105MSI germination protein ypeb BWEI_RS10860 ENOG4105CIS alcohol dehydrogenase BWEI_RS10890 ENOG4106NZI LysR family Transcriptional regulator BWEI_RS10895 ENOG4105CPC Aldo Keto reductase BWEI_RS10940 ENOG4105D6E homoserine dehydrogenase BWEI_RS10955 ENOG4105ETU transcriptional activator (TenA BWEI_RS11045 ENOG410667J hydrolase BWEI_RS11050 ENOG4105BZU Histidine kinase BWEI_RS11055 ENOG4107RF6 penicillin-binding protein BWEI_RS11060 ENOG4105C3F Signal peptidase i BWEI_RS11080 ENOG4108JJB ABC transporter BWEI_RS11090 ENOG4108HGU Histidine kinase BWEI_RS11110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS11115 ENOG4105GR3 Histidine kinase BWEI_RS11120 ENOG4105CB2 alcohol dehydrogenase BWEI_RS11125 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BWEI_RS11130 ENOG4105CJN penicillin-binding protein BWEI_RS11165 ENOG4107Y80 Major Facilitator superfamily BWEI_RS11175 ENOG4105KVH Transcriptional regulator BWEI_RS11190 ENOG4107VXM glycerophosphoryl diester phosphodiesterase BWEI_RS11210 ENOG4107Y9U Membrane BWEI_RS11250 ENOG4105FCD Major Facilitator BWEI_RS11255 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BWEI_RS11260 ENOG4108Z4K mutator MutT protein BWEI_RS11285 ENOG4108XI2 Domain of unknown function (DUF1963) BWEI_RS11310 ENOG4108NRW Phospholipase, patatin family BWEI_RS11315 ENOG4105KWG Pfam:DUF1696 BWEI_RS11350 ENOG4105PKS Excinuclease abc c subunit domain protein BWEI_RS11370 ENOG4107RA9 decarboxylase BWEI_RS11375 ENOG4105BZ1 (ABC) transporter BWEI_RS11385 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BWEI_RS11390 ENOG4107VFR oxidoreductase BWEI_RS11420 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS11425 ENOG4105BZU Histidine kinase BWEI_RS11450 ENOG4107WD8 ABC transporter, permease BWEI_RS11470 ENOG4105DY8 decarboxylase BWEI_RS11485 ENOG4108IUM Glycogen debranching enzyme BWEI_RS11495 ENOG4105CGH 5'-nucleotidase BWEI_RS11505 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BWEI_RS11510 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BWEI_RS11515 ENOG4105FDR Membrane BWEI_RS11520 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS11535 ENOG410900G Protein of unknown function (DUF421) BWEI_RS11560 ENOG4105CHR reductase BWEI_RS11575 ENOG4105SX7 Transporter BWEI_RS11610 ENOG4105KVH Transcriptional regulator BWEI_RS11615 ENOG4105CHR reductase BWEI_RS11640 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BWEI_RS11665 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BWEI_RS11685 ENOG4105DZ1 carboxypeptidase BWEI_RS11735 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BWEI_RS11740 ENOG4107QX3 carboxylase BWEI_RS11745 ENOG4105E39 Enoyl-CoA hydratase BWEI_RS11750 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BWEI_RS11755 ENOG4106063 Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BWEI_RS11760 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BWEI_RS11765 ENOG4105C1G acyl-Coa dehydrogenase BWEI_RS11775 ENOG4107Z3H Transcriptional regulator, TetR family BWEI_RS11785 ENOG4105CJ1 ABC, transporter BWEI_RS11795 ENOG4107RGJ metallophosphoesterase BWEI_RS11805 ENOG4108NQ3 Phosphatidylinositol-specific phospholipase C BWEI_RS11810 ENOG4108M1A Chitin-binding protein BWEI_RS11840 ENOG4105E1K spore germination protein BWEI_RS11855 ENOG4107TPS domain protein BWEI_RS11860 ENOG4105CEP NADH dehydrogenase BWEI_RS11905 ENOG4107RF6 penicillin-binding protein BWEI_RS11910 ENOG4107RF6 penicillin-binding protein BWEI_RS11920 ENOG4105EMN RNA polymerase sigma factor BWEI_RS11950 ENOG4107RVG penicillin-binding protein BWEI_RS12005 ENOG4105C19 ABC transporter BWEI_RS12010 ENOG4105EQK -acetyltransferase BWEI_RS12025 ENOG4105CIN aminoacyl-histidine dipeptidase BWEI_RS12060 ENOG4108V4B ThiJ pfpI BWEI_RS12075 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BWEI_RS12090 ENOG4108RZE Tetr family transcriptional regulator BWEI_RS12095 ENOG4105C1J atp-dependent rna helicase BWEI_RS12130 ENOG4107STF Involved in phosphonate degradation (By similarity) BWEI_RS12140 ENOG4105RD7 BadF BadG BcrA BcrD BWEI_RS12165 ENOG4105F32 YngK protein BWEI_RS12190 ENOG4108KPJ rna polymerase sigma factor BWEI_RS12195 ENOG4108KJ0 anaerobic glycerol-3-phosphate dehydrogenase, subunit B BWEI_RS12205 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BWEI_RS12230 ENOG4108JCI Transcriptional regulator BWEI_RS12235 ENOG4108VP3 Lysine exporter protein (LysE YggA) BWEI_RS12265 ENOG4105BZ1 (ABC) transporter BWEI_RS12270 ENOG4105BZ1 (ABC) transporter BWEI_RS12285 ENOG4108RPX mosc domain containing protein BWEI_RS12290 ENOG4108JPW Aminotransferase BWEI_RS12295 ENOG4105DND Transcriptional regulator BWEI_RS12310 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BWEI_RS12315 ENOG4107V2S Transcriptional regulator BWEI_RS12345 ENOG41068WN BWEI_RS12355 ENOG4105C1Q protoporphyrinogen oxidase BWEI_RS12385 ENOG4105WCN acetyltransferase BWEI_RS12395 ENOG4108NHD germination protein BWEI_RS12400 ENOG4108Q8B Spore germination protein BWEI_RS12410 ENOG4105EYF MMPL domain protein BWEI_RS12415 ENOG41067SE Tetr family transcriptional regulator BWEI_RS12430 ENOG4107MII Sugar-specific transcriptional regulator TrmB BWEI_RS12450 ENOG4108Y4K DNA-binding transcriptional activator BWEI_RS12460 ENOG41081I9 integral membrane protein BWEI_RS12475 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) BWEI_RS12480 ENOG4105C37 (CBS) domain BWEI_RS12505 ENOG4107SKW Inherit from COG: Alpha beta hydrolase BWEI_RS12515 ENOG4105C19 ABC transporter BWEI_RS12525 ENOG4105VMP Transcriptional regulator BWEI_RS12530 ENOG4105C22 threonyL-tRNA synthetase BWEI_RS12535 ENOG4105FE9 pseudouridine synthase BWEI_RS12560 ENOG4105BZG amino acid carrier protein BWEI_RS12575 ENOG4105K70 DNA-binding protein BWEI_RS12590 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS12595 ENOG4105WQT MbtH domain protein BWEI_RS12600 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS12605 ENOG4105WQI isochorismatase BWEI_RS12610 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BWEI_RS12615 ENOG4105E4F Isochorismate synthase BWEI_RS12620 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase BWEI_RS12625 ENOG4105FCD Major Facilitator BWEI_RS12645 ENOG4105EYH Exonuclease BWEI_RS12650 ENOG4107RFY SbcCD D subunit BWEI_RS12665 ENOG4105E39 Enoyl-CoA hydratase BWEI_RS12670 ENOG4105N14 lysine exporter protein LysE YggA BWEI_RS12680 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BWEI_RS12685 ENOG4105C1G acyl-Coa dehydrogenase BWEI_RS12690 ENOG4105CR4 methylisocitrate lyase BWEI_RS12695 ENOG4105DXD 2-methylcitrate dehydratase BWEI_RS12705 ENOG4105CZM Major Facilitator BWEI_RS12715 ENOG4105BZ4 penicillin-binding protein BWEI_RS12735 ENOG4105CHR reductase BWEI_RS12760 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BWEI_RS12830 ENOG4105SZ6 Thioredoxin BWEI_RS12840 ENOG410841Q phosphoesterase PA-phosphatase related protein BWEI_RS12925 ENOG4107Y5K Resolvase BWEI_RS12940 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BWEI_RS12945 ENOG4108JUB Transcriptional regulator BWEI_RS12950 ENOG4108TSC N-acetyltransferase BWEI_RS12955 ENOG4107S4Y M20 DapE family protein YgeY BWEI_RS12970 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BWEI_RS12995 ENOG4105C37 (CBS) domain BWEI_RS13040 ENOG4105E90 ABC transporter BWEI_RS13045 ENOG4108IJ8 ABC transporter BWEI_RS13070 ENOG4105C6Z Gluconate BWEI_RS13075 ENOG4105CMG Carbohydrate kinase BWEI_RS13100 ENOG4106KNT transcriptional regulator BWEI_RS13105 ENOG4105WH1 Two component transcriptional regulator luxr family BWEI_RS13110 ENOG4105BZU Histidine kinase BWEI_RS13115 ENOG4105D8X mechanosensitive ion channel BWEI_RS13140 ENOG4105F0I Aminotransferase BWEI_RS13145 ENOG4108MES Periplasmic binding protein BWEI_RS13150 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BWEI_RS13160 ENOG4105CAQ asparagine synthetase BWEI_RS13165 ENOG4107Y70 Heat shock protein BWEI_RS13170 ENOG4108KF3 Electron transport protein SCO1 SenC BWEI_RS13175 ENOG4105E8R UPF0173 metal-dependent hydrolase BWEI_RS13180 ENOG4108RCR degv family BWEI_RS13190 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BWEI_RS13200 ENOG4108UT2 hemolysin iii BWEI_RS13205 ENOG4105E9Q Acyl-transferase BWEI_RS13215 ENOG4107RVG penicillin-binding protein BWEI_RS13255 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BWEI_RS13275 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BWEI_RS13280 ENOG4105KD7 acetyltransferase BWEI_RS13300 ENOG4105CY2 Citrate transporter BWEI_RS13305 ENOG4107XGZ Hydrolase BWEI_RS13325 ENOG4105C8J )-transporter BWEI_RS13375 ENOG4105EC2 ftsk spoIIIe BWEI_RS13395 ENOG4105C5S asparaginyl-tRNA synthetase BWEI_RS13400 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BWEI_RS13425 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BWEI_RS13445 ENOG4105C75 arginyL-tRNA synthetase BWEI_RS13450 ENOG4107YX5 Pfam:DUF548 BWEI_RS13470 ENOG4108UUM single-stranded DNA-binding protein BWEI_RS13485 ENOG4105C5H ABC transporter BWEI_RS13565 ENOG4107T65 Integrase BWEI_RS13570 ENOG4105MCT stage V sporulation protein S BWEI_RS13600 ENOG4105FJH Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity) BWEI_RS13605 ENOG4108IFG nitrite reductase, (NAD(P)H) BWEI_RS13610 ENOG4105KH3 nitrite reductase (NAD(P)h) small subunit BWEI_RS13615 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BWEI_RS13620 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BWEI_RS13625 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BWEI_RS13640 ENOG4105GAK amidohydrolase 2 BWEI_RS13660 ENOG4108ZAF Molybdopterin BWEI_RS13665 ENOG4105CVM Molybdenum cofactor synthesis domain protein BWEI_RS13670 ENOG4105D06 uba thif-type nad fad binding protein BWEI_RS13675 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BWEI_RS13680 ENOG4107V6Q Cyclic nucleotide-binding domain BWEI_RS13690 ENOG4105R3A Nitrate reductase BWEI_RS13695 ENOG4108IUE nitrate reductase beta subunit BWEI_RS13715 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BWEI_RS13730 ENOG4108V06 Glutathione peroxidase BWEI_RS13740 ENOG4105CNW domain protein BWEI_RS13760 ENOG4105EMN RNA polymerase sigma factor BWEI_RS13765 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BWEI_RS13775 ENOG41083WA Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily BWEI_RS13780 ENOG4105CJK Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity) BWEI_RS13800 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BWEI_RS13825 ENOG4105KBJ sporulation protein ytfj BWEI_RS13845 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BWEI_RS13870 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS13875 ENOG4108JYZ YitT family BWEI_RS13880 ENOG41087PP glycosyltransferase MGT family BWEI_RS13895 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BWEI_RS13900 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BWEI_RS13910 ENOG4108X4Q Hydrolase BWEI_RS13920 ENOG4108ZRV stage ii sporulation protein p BWEI_RS13945 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BWEI_RS13950 ENOG4108VXD carboxy-peptidase BWEI_RS13960 ENOG4108ZRV stage ii sporulation protein p BWEI_RS13975 ENOG4108Z7R Chaperone CsaA BWEI_RS13995 ENOG4105C37 (CBS) domain BWEI_RS14000 ENOG4105SXS Protein of unknown function (DUF456) BWEI_RS14025 ENOG4108S4H thioesterase Superfamily protein BWEI_RS14035 ENOG4108PJD permease BWEI_RS14050 ENOG4107T5V SNARE associated Golgi BWEI_RS14070 ENOG4107TB6 phosphoglycerate mutase BWEI_RS14095 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BWEI_RS14115 ENOG4105DSE periplasmic solute binding protein BWEI_RS14135 ENOG4105CKI cobalamin synthesis protein BWEI_RS14140 ENOG4107QM2 Aldo Keto reductase BWEI_RS14145 ENOG4105VMI -acetyltransferase BWEI_RS14160 ENOG4105DEN Luciferase family BWEI_RS14175 ENOG4108WPJ Ferritin-like domain BWEI_RS14180 ENOG4108K88 Membrane BWEI_RS14195 ENOG4105C8Q Methyl-accepting chemotaxis BWEI_RS14225 ENOG4105CPC Aldo Keto reductase BWEI_RS14230 ENOG4105YVS arsR family transcriptional regulator BWEI_RS14240 ENOG4105KRN Transcriptional regulator, abrb family BWEI_RS14285 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS14290 ENOG4108ZUB Lysine exporter protein (Lyse ygga) BWEI_RS14300 ENOG4105YWU small acid-soluble spore protein BWEI_RS14305 ENOG4108WBH protein TIM barrel BWEI_RS14320 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS14325 ENOG4105DUU IucA IucC family protein BWEI_RS14335 ENOG4105VRR gCN5-related N-acetyltransferase BWEI_RS14340 ENOG4105KT7 mgtC SapB transporter BWEI_RS14345 ENOG4105D7V transposase BWEI_RS14360 ENOG4105BZU Histidine kinase BWEI_RS14365 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BWEI_RS14375 ENOG4108KGH TRANSCRIPTIONal BWEI_RS14400 ENOG4105D6E homoserine dehydrogenase BWEI_RS14425 ENOG41075D4 Aminoglycoside 6-adenylyltransferase BWEI_RS14440 ENOG4105BZU Histidine kinase BWEI_RS14445 ENOG4105EFI regulatoR BWEI_RS14450 ENOG4105BZ1 (ABC) transporter BWEI_RS14505 ENOG4108JJ8 (ABC) transporter BWEI_RS14510 ENOG4108JJ9 ABC, transporter BWEI_RS14515 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BWEI_RS14520 ENOG4105C4M (Ubiquinol oxidase) subunit I BWEI_RS14545 ENOG4105MDS 4-oxalocrotonate tautomerase BWEI_RS14555 ENOG410825D TRANSCRIPTIONal REGULATOR, LysR family BWEI_RS14565 ENOG4105C32 Amino acid ABC transporter (Permease) BWEI_RS14570 ENOG4108IV0 ABC, transporter BWEI_RS14575 ENOG4105C0Z ABC transporter BWEI_RS14585 ENOG4105CKI cobalamin synthesis protein BWEI_RS14595 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BWEI_RS14605 ENOG4106F5Q Membrane BWEI_RS14610 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) BWEI_RS14625 ENOG4108TVJ Nitroreductase BWEI_RS14630 ENOG4107ZXU DSBA oxidoreductase BWEI_RS14635 ENOG4108Z40 Transcriptional regulator BWEI_RS14640 ENOG4105GZI Transcriptional regulator BWEI_RS14645 ENOG4107RT3 EamA-like transporter family BWEI_RS14655 ENOG4105KTB nuclear export factor GLE1 BWEI_RS14660 ENOG4108T5E Copper resistance protein BWEI_RS14705 ENOG4105FQP Beta-lactamase BWEI_RS14715 ENOG4107TUM Amidinotransferase BWEI_RS14745 ENOG4105C5Q Transcriptional regulator BWEI_RS14765 ENOG4107R16 Multicopper oxidase BWEI_RS14770 ENOG4107RAQ aminopeptidase BWEI_RS14815 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BWEI_RS14820 ENOG4105D9N nucleoside BWEI_RS14835 ENOG4107RHR regulatoR BWEI_RS14850 ENOG4105KNA -acetyltransferase BWEI_RS14855 ENOG4105MDH Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity) BWEI_RS14865 ENOG410829K Lysine exporter protein (Lyse ygga) BWEI_RS14885 ENOG4105C0X amino acid BWEI_RS14895 ENOG41063V1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BWEI_RS14910 ENOG4105C56 H( )-stimulated, divalent metal cation uptake system (By similarity) BWEI_RS14930 ENOG41068WN BWEI_RS14995 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BWEI_RS15000 ENOG4105C6X Major Facilitator BWEI_RS15025 ENOG4105C7B Threonine dehydratase BWEI_RS15035 ENOG4105CHR reductase BWEI_RS15040 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS15045 ENOG4105BZU Histidine kinase BWEI_RS15055 ENOG4105E3B Multicopper oxidase BWEI_RS15060 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BWEI_RS15080 ENOG4105H67 Protein of unknown function (DUF421) BWEI_RS15085 ENOG4105X5K response regulator receiver protein BWEI_RS15095 ENOG4105C8J )-transporter BWEI_RS15115 ENOG4105C6T cysteine synthase BWEI_RS15120 ENOG4105EU0 Major facilitator Superfamily BWEI_RS15125 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BWEI_RS15140 ENOG4105DXI Major Facilitator superfamily BWEI_RS15150 ENOG4105CSR polyphosphate kinase 2 BWEI_RS15190 ENOG4105FVX BWEI_RS15245 ENOG4105C6K Malic enzyme BWEI_RS15250 ENOG4108IJ0 Aspartate ammonia-lyase BWEI_RS15260 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BWEI_RS15280 ENOG4105CJ1 ABC, transporter BWEI_RS15315 ENOG4106BRA Membrane BWEI_RS15335 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BWEI_RS15340 ENOG4107QIV Cytochrome c biogenesis protein BWEI_RS15360 ENOG4105EC3 peptidase S51, dipeptidase E BWEI_RS15365 ENOG4107QJQ Mate efflux family protein BWEI_RS15385 ENOG4105DNP FAD linked oxidase domain protein BWEI_RS15390 ENOG4105C9Q fumarate hydratase class II BWEI_RS15395 ENOG4105DFD Na H antiporter BWEI_RS15405 ENOG4108UZ3 Transporter BWEI_RS15410 ENOG4105DRR Transcriptional regulator, GntR family BWEI_RS15420 ENOG4105PGM cation diffusion facilitator family transporter BWEI_RS15440 ENOG4105CAQ asparagine synthetase BWEI_RS15465 ENOG4105CVJ phosphoglycerate mutase BWEI_RS15500 ENOG4108N53 binding-protein-dependent transport systems inner membrane Component BWEI_RS15510 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BWEI_RS15540 ENOG4108U4N (sortase) family BWEI_RS15560 ENOG4105KAC Antibiotic biosynthesis monooxygenase BWEI_RS15595 ENOG4105KTQ flagellar basal-body rod protein BWEI_RS15600 ENOG4105FZW flagellar biosynthesis regulator FlhF BWEI_RS15605 ENOG4105D7B Flagellar biosynthesis protein flha BWEI_RS15610 ENOG4105D00 flagellar biosynthetic protein flhB BWEI_RS15620 ENOG4105VS8 Flagellar biosynthetic protein fliq BWEI_RS15625 ENOG4105CN7 Flagellar biosynthetic protein FliP BWEI_RS15635 ENOG4105DD5 Flagellar motor switch protein BWEI_RS15640 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BWEI_RS15650 ENOG4105E4C Lytic transglycosylase catalytic BWEI_RS15655 ENOG4105I03 Flagellin BWEI_RS15665 ENOG4105D1F ATP-binding protein BWEI_RS15670 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BWEI_RS15675 ENOG41067WU Molybdopterin converting factor (Subunit 1) BWEI_RS15680 ENOG4108ZAF Molybdopterin BWEI_RS15685 ENOG4105CVM Molybdenum cofactor synthesis domain protein BWEI_RS15690 ENOG4105D06 uba thif-type nad fad binding protein BWEI_RS15695 ENOG4105TMB Formate nitrite transporter BWEI_RS15705 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BWEI_RS15710 ENOG4108ZSU Uncharacterized conserved protein (DUF2294) BWEI_RS15720 ENOG4108JB9 formate dehydrogenase BWEI_RS15730 ENOG4107TS3 membrane protein, TerC BWEI_RS15735 ENOG4105BZU Histidine kinase BWEI_RS15750 ENOG4107R88 Chemotaxis protein (CheV) BWEI_RS15765 ENOG4105BZE flagellar hook protein, FlgE BWEI_RS15795 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BWEI_RS15800 ENOG4107U2N Flagellar M-ring protein BWEI_RS15810 ENOG4108ZC9 flagellar basal-body rod protein flgc BWEI_RS15815 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BWEI_RS15840 ENOG4105DTJ flagellar hook-associated protein BWEI_RS15845 ENOG4105E1Q flagellar hook-associated protein BWEI_RS15865 ENOG4105BZU Histidine kinase BWEI_RS15880 ENOG4105DD5 Flagellar motor switch protein BWEI_RS15885 ENOG4105CBS Chea signal transduction histidine kinase BWEI_RS15890 ENOG4107YTP response regulator receiver protein BWEI_RS15895 ENOG4105ER2 Ompa motb domain protein BWEI_RS15900 ENOG4107R0U MotA TolQ exbB proton channel BWEI_RS15910 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BWEI_RS15945 ENOG4105DQ6 Transposase BWEI_RS15960 ENOG41080C8 DUF218 domain BWEI_RS15965 ENOG4105H67 Protein of unknown function (DUF421) BWEI_RS15975 ENOG4108Z5V transcriptional regulator, merr family BWEI_RS15980 ENOG4107RWR Sodium hydrogen exchanger BWEI_RS15990 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BWEI_RS16050 ENOG41081VK Ribonuclease BWEI_RS16070 ENOG4108SZE gCN5-related N-acetyltransferase BWEI_RS16085 ENOG4105CPK Glycosyl transferase (Group 1 BWEI_RS16155 ENOG4105KHC sulfurtransferase BWEI_RS16165 ENOG4108W0I acetyltransferase BWEI_RS16175 ENOG410890F Dynamin family BWEI_RS16180 ENOG4105DHF Membrane BWEI_RS16185 ENOG4105C2W permease BWEI_RS16195 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BWEI_RS16205 ENOG4105CTD carboxy-peptidase BWEI_RS16210 ENOG4105DVT helicase BWEI_RS16220 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BWEI_RS16270 ENOG4105BZ4 penicillin-binding protein BWEI_RS16280 ENOG4105CSM endonuclease III BWEI_RS16300 ENOG4105DVT helicase BWEI_RS16330 ENOG4105CPK Glycosyl transferase (Group 1 BWEI_RS16335 ENOG4105FJR Lmbe family BWEI_RS16350 ENOG4108ZPQ MazG nucleotide pyrophosphohydrolase BWEI_RS16355 ENOG4108JYZ YitT family BWEI_RS16390 ENOG4105PE6 Menaquinol-cytochrome c reductase, cytochrome b c subunit BWEI_RS16395 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BWEI_RS16400 ENOG4105DQV Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity) BWEI_RS16415 ENOG41068YB TPR repeat-containing protein BWEI_RS16420 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BWEI_RS16435 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BWEI_RS16440 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BWEI_RS16445 ENOG4105EAH synthase BWEI_RS16455 ENOG4105XXQ heptaprenyl diphosphate synthase component I BWEI_RS16470 ENOG4105DXU ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity) BWEI_RS16500 ENOG41065D1 BWEI_RS16505 ENOG4105S2F BWEI_RS16535 ENOG4107RB3 L-asparaginase BWEI_RS16540 ENOG4105E4T pyridine nucleotide-disulfide oxidoreductase BWEI_RS16565 ENOG4108S6Z Negative regulator of genetic competence BWEI_RS16570 ENOG4107X2D transcriptional regulator, merr family BWEI_RS16575 ENOG4107RGJ metallophosphoesterase BWEI_RS16585 ENOG4105I7S Abortive infection protein BWEI_RS16590 ENOG4105C9U ATP-dependent DNA helicase RecQ BWEI_RS16595 ENOG4105T7X BWEI_RS16605 ENOG4108SAX Membrane BWEI_RS16615 ENOG41063SB peptidase BWEI_RS16620 ENOG4108WBT adenosyltransferase BWEI_RS16625 ENOG4105BZU Histidine kinase BWEI_RS16630 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS16635 ENOG4105CRE cytochrome C BWEI_RS16640 ENOG4107TWT Cytochrome c biogenesis protein BWEI_RS16650 ENOG4105FE9 pseudouridine synthase BWEI_RS16660 ENOG4108JIC nucleoside recognition domain protein BWEI_RS16665 ENOG4105DZ1 carboxypeptidase BWEI_RS16670 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BWEI_RS16700 ENOG4105BZU Histidine kinase BWEI_RS16715 ENOG4105I3N Conserved Protein BWEI_RS16720 ENOG4105BZU Histidine kinase BWEI_RS16735 ENOG4105BZ4 penicillin-binding protein BWEI_RS16740 ENOG4107GRR phosphate transport regulator BWEI_RS16745 ENOG4105CJ3 phosphate transporter BWEI_RS16790 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BWEI_RS16810 ENOG4105WH1 Two component transcriptional regulator luxr family BWEI_RS16815 ENOG4105ENE Histidine kinase BWEI_RS16840 ENOG4105DFD Na H antiporter BWEI_RS16860 ENOG4105C8J )-transporter BWEI_RS16865 ENOG41087GM Siroheme synthase (Precorrin-2 oxidase ferrochelatase domain)-like protein BWEI_RS16870 ENOG4105DAT cobalamin (vitamin b12) biosynthesis cbix protein BWEI_RS16875 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BWEI_RS16885 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BWEI_RS16890 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BWEI_RS16905 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BWEI_RS16915 ENOG4105E0M Sulfatase BWEI_RS16920 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BWEI_RS16930 ENOG4107RVV histidinol phosphate phosphatase, hisj family BWEI_RS17005 ENOG4108ZP8 Acetolactate synthase small subunit BWEI_RS17010 ENOG4105C7K acetolactate synthase BWEI_RS17015 ENOG4105CM2 brancheD-chain amino acid aminotransferase BWEI_RS17035 ENOG4105KBJ sporulation protein ytfj BWEI_RS17045 ENOG4105CZN Potassium uptake protein BWEI_RS17080 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BWEI_RS17085 ENOG4107QMU Mate efflux family protein BWEI_RS17120 ENOG4105NQC Flavodoxin BWEI_RS17140 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BWEI_RS17150 ENOG4108M4D D-alanyl-lipoteichoic acid biosynthesis protein DltD BWEI_RS17155 ENOG4105EA8 2-Nitropropane dioxygenase BWEI_RS17160 ENOG4105EBE Peptidase U61, LD-carboxypeptidase A BWEI_RS17200 ENOG4105CJ1 ABC, transporter BWEI_RS17210 ENOG4105CZV ABC transporter BWEI_RS17215 ENOG4105W8V TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS17220 ENOG4105C8Y Acetylornithine aminotransferase BWEI_RS17230 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BWEI_RS17245 ENOG4105D82 Glutamate dehydrogenase BWEI_RS17250 ENOG4105CUB amino acid BWEI_RS17255 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BWEI_RS17270 ENOG4105G3E Probably involved in ribonucleotide reductase function (By similarity) BWEI_RS17285 ENOG4108R6G acetyltransferase BWEI_RS17310 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BWEI_RS17315 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BWEI_RS17325 ENOG4105BZU Histidine kinase BWEI_RS17335 ENOG4106DF1 BWEI_RS17345 ENOG41090MY MarR family Transcriptional regulator BWEI_RS17350 ENOG4105BZU Histidine kinase BWEI_RS17360 ENOG4105PXI polysaccharide deacetylase BWEI_RS17370 ENOG4107V49 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity) BWEI_RS17380 ENOG4105E98 transcriptional regulator DeoR family BWEI_RS17400 ENOG4107RCV ABC transporter, permease BWEI_RS17405 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BWEI_RS17410 ENOG4105C4Y ABC transporter BWEI_RS17440 ENOG4105CHR reductase BWEI_RS17460 ENOG4108Z7G MaoC domain protein dehydratase BWEI_RS17465 ENOG410681C small acid-soluble spore protein BWEI_RS17470 ENOG4105CZN Potassium uptake protein BWEI_RS17475 ENOG4107TS3 membrane protein, TerC BWEI_RS17480 ENOG4108QTI )-transporter BWEI_RS17490 ENOG4106A3R peptidase BWEI_RS17510 ENOG4105JXH GntR family transcriptional regulator BWEI_RS17515 ENOG4105BZU Histidine kinase BWEI_RS17520 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS17535 ENOG4105CQB FAD linked oxidase domain protein BWEI_RS17540 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BWEI_RS17545 ENOG4105K4I Scp-like extracellular BWEI_RS17555 ENOG4108YBP pseudouridine synthase BWEI_RS17565 ENOG4105EYF MMPL domain protein BWEI_RS17575 ENOG4107RUE extracellular solute-binding protein family 1 BWEI_RS17580 ENOG4105D38 putrescine abc transporter BWEI_RS17585 ENOG4105F38 ABC transporter, permease BWEI_RS17595 ENOG4105C26 Dehydrogenase BWEI_RS17630 ENOG4105VFR signal peptidase BWEI_RS17635 ENOG4105DZ1 carboxypeptidase BWEI_RS17680 ENOG4105VZ8 Transcriptional regulator BWEI_RS17690 ENOG4105C7S Dehydrogenase BWEI_RS17710 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BWEI_RS17795 ENOG4105DDQ anthranilate synthase BWEI_RS17810 ENOG4105CK7 Sodium proline symporter BWEI_RS17895 ENOG4105DBZ Dtdp-4-dehydrorhamnose reductase BWEI_RS17905 ENOG4108URP Dtdp-4-dehydrorhamnose 3,5-epimerase BWEI_RS17910 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BWEI_RS17930 ENOG4107TVC Glycosyl transferase, family 2 BWEI_RS17950 ENOG4105K64 Glycosyl transferase, family 2 BWEI_RS17970 ENOG4105EMS pseudouridine synthase BWEI_RS17975 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BWEI_RS17990 ENOG4105MIX Adenylate cyclase BWEI_RS17995 ENOG4108Z18 K06886 hemoglobin BWEI_RS18005 ENOG4105DPN Oligoendopeptidase f BWEI_RS18015 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BWEI_RS18025 ENOG4108ZCF integral membrane protein BWEI_RS18045 ENOG4105UQX Mate efflux family protein BWEI_RS18050 ENOG4108JQ7 (ABC) transporter BWEI_RS18060 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BWEI_RS18065 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BWEI_RS18080 ENOG4105C31 Tryptophanyl-tRNA synthetase BWEI_RS18100 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BWEI_RS18105 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BWEI_RS18140 ENOG4108KP7 hydrolase BWEI_RS18155 ENOG4107AYK membrAne BWEI_RS18160 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BWEI_RS18185 ENOG4108VJ1 Transcriptional regulator (CarD family BWEI_RS18200 ENOG4105QNR S1 RNA binding domain protein BWEI_RS18215 ENOG4105BZU Histidine kinase BWEI_RS18220 ENOG4105CH6 catalase BWEI_RS18230 ENOG4105CAQ asparagine synthetase BWEI_RS18255 ENOG4105ERH Fumarylacetoacetate hydrolase BWEI_RS18325 ENOG4105XVF Competence transcription factor BWEI_RS18355 ENOG4107QP3 malate synthase g BWEI_RS18380 ENOG4105C2Y STE24 endopeptidase EC 3.4.24.84 BWEI_RS18395 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BWEI_RS18405 ENOG41086D8 Transcriptional regulator BWEI_RS18410 ENOG4108AEY RNA polymerase sigma factor BWEI_RS18425 ENOG4107TVP HD domain protein BWEI_RS18430 ENOG4107RN3 metallophosphoesterase BWEI_RS18470 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS18480 ENOG4105DF9 Lipoate-protein, ligase BWEI_RS18485 ENOG4108RQ5 Beta-lactamase domain-containing protein BWEI_RS18525 ENOG4105ECB domain protein BWEI_RS18525 ENOG4105ECB domain protein BWEI_RS18550 ENOG4105C1Q protoporphyrinogen oxidase BWEI_RS18565 ENOG4105BZ4 penicillin-binding protein BWEI_RS18570 ENOG4105Q24 Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation BWEI_RS18575 ENOG4105CKV Membrane BWEI_RS18580 ENOG410905X membrane-flanked domain protein BWEI_RS18620 ENOG4105CKV Membrane BWEI_RS18625 ENOG410905X membrane-flanked domain protein BWEI_RS18685 ENOG4105K59 histidine triad (HIT) protein BWEI_RS18710 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) BWEI_RS18715 ENOG4105EEM helicase BWEI_RS18730 ENOG4105EMN RNA polymerase sigma factor BWEI_RS18735 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BWEI_RS18750 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BWEI_RS18755 ENOG41067QW Transcriptional regulator BWEI_RS18770 ENOG4108MUZ hydrolase BWEI_RS18780 ENOG4107JM4 Tetratricopeptide repeat BWEI_RS18805 ENOG4106D4I domain protein BWEI_RS18810 ENOG4107VRP DNA repair exonuclease BWEI_RS18830 ENOG4108VB1 regulatoR BWEI_RS18835 ENOG4105ENE Histidine kinase BWEI_RS18855 ENOG4105C6F GntR Family Transcriptional Regulator BWEI_RS18860 ENOG4105DJ2 Major Facilitator Superfamily BWEI_RS18885 ENOG4105BZU Histidine kinase BWEI_RS18890 ENOG4105BZU Histidine kinase BWEI_RS18895 ENOG4108MJI response regulator BWEI_RS18905 ENOG4108N6D Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS18915 ENOG4105WN5 stage II sporulation protein BWEI_RS19020 ENOG4107RBI VanW family BWEI_RS19045 ENOG4105FBW Monooxygenase BWEI_RS19075 ENOG4105CMT Dihydroxyacetone kinase BWEI_RS19095 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase BWEI_RS19105 ENOG4105CS2 ec 3.2.1.21 BWEI_RS19110 ENOG4105C5Y PTS System BWEI_RS19115 ENOG4105CID antiterminator BWEI_RS19120 ENOG4105DQ6 Transposase BWEI_RS19140 ENOG4105WAB arsR family transcriptional regulator BWEI_RS19145 ENOG4105F27 Major Facilitator BWEI_RS19150 ENOG41067XF inhibitor BWEI_RS19210 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS19235 ENOG4105CDU Replicative dna helicase BWEI_RS19265 ENOG4107SCJ type I restriction enzyme EcoKI subunit R BWEI_RS19290 ENOG4108MRH transcriptional regulatory protein BWEI_RS19300 ENOG4105CSH Transporter BWEI_RS19315 ENOG4108JQ7 (ABC) transporter BWEI_RS19320 ENOG4105C3U ABC transporter BWEI_RS19325 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BWEI_RS19365 ENOG4105D5U fad dependent oxidoreductase BWEI_RS19395 ENOG4105DER m42 family BWEI_RS19410 ENOG4105CGU Enoyl-CoA hydratase BWEI_RS19425 ENOG4105CK0 Membrane bOund o-acyl transferase mboat family protein BWEI_RS19435 ENOG4106AKK s-layer domain-containing protein BWEI_RS19470 ENOG4105CHH sulfate transporter BWEI_RS19490 ENOG4107ZTW SNARE associated Golgi BWEI_RS19495 ENOG4105CEY Amp-dependent synthetase and ligase BWEI_RS19500 ENOG4105D4P Coproporphyrinogen iii oxidase BWEI_RS19505 ENOG4108VPC n-acetylmuramoyl-l-alanine amidase BWEI_RS19520 ENOG4107R51 Glycosyl transferase, family 2 BWEI_RS19525 ENOG4106WTF Glycosyl transferase, family 2 BWEI_RS19530 ENOG4107FQX Alpha-acetolactate decarboxylase BWEI_RS19565 ENOG410839P BWEI_RS19580 ENOG4105CDA abc transporter atp-binding protein BWEI_RS19585 ENOG4105DRP amino acid AbC transporter BWEI_RS19595 ENOG4105BZ1 (ABC) transporter BWEI_RS19600 ENOG4105BZ1 (ABC) transporter BWEI_RS19605 ENOG4105C26 Dehydrogenase BWEI_RS19610 ENOG4105D5Q Arginine ornithine antiporter BWEI_RS19620 ENOG4107RKG DJ-1/PfpI family BWEI_RS19635 ENOG4108MXQ glutathione-regulated potassium-efflux system ancillary protein KefF BWEI_RS19660 ENOG4105KPY Small multidrug resistance protein BWEI_RS19675 ENOG4108IXY short-chain dehydrogenase reductase BWEI_RS19685 ENOG4108YXU transcriptional regulator AsnC family BWEI_RS19690 ENOG4108PCN EamA-like transporter family BWEI_RS19730 ENOG4106KNT transcriptional regulator BWEI_RS19740 ENOG4107RWR Sodium hydrogen exchanger BWEI_RS19745 ENOG4105CUB amino acid BWEI_RS19775 ENOG4107T5V SNARE associated Golgi BWEI_RS19800 ENOG4105WEF catalase BWEI_RS19835 ENOG4105C19 ABC transporter BWEI_RS19840 ENOG4107RBB ABC transporter, permease BWEI_RS19845 ENOG41069ER domain protein BWEI_RS19865 ENOG4105VZJ PTS System BWEI_RS19870 ENOG4105VCP PTS System BWEI_RS19875 ENOG4105EMD TRANSCRIPTIONal BWEI_RS19890 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BWEI_RS19905 ENOG4108KGH TRANSCRIPTIONal BWEI_RS19915 ENOG41087NI Sulfite exporter TauE/SafE BWEI_RS19920 ENOG4105HF9 Inherit from COG: pyridine nucleotide-disulfide oxidoreductase BWEI_RS19925 ENOG4105VFE sira family BWEI_RS19930 ENOG4105VFE sira family BWEI_RS19935 ENOG4107TPS domain protein BWEI_RS19940 ENOG4105VFE sira family BWEI_RS19945 ENOG4105XTG Pfam:DUF156 BWEI_RS19970 ENOG4105ED1 spovr family BWEI_RS19975 ENOG4107Y03 Nitroreductase BWEI_RS19995 ENOG4108B31 Spore germination protein BWEI_RS20015 ENOG4105K63 Thioredoxin BWEI_RS20030 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BWEI_RS20040 ENOG4105C7N Xanthine uracil vitamin C permease BWEI_RS20050 ENOG4108INS Transcriptional regulator BWEI_RS20100 ENOG4105DWF phosphomethylpyrimidine kinase BWEI_RS20105 ENOG4105D06 uba thif-type nad fad binding protein BWEI_RS20120 ENOG41080HI glycine oxidase BWEI_RS20125 ENOG4108VEU Thiamine monophosphate synthase BWEI_RS20135 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BWEI_RS20145 ENOG4105ETU transcriptional activator (TenA BWEI_RS20150 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BWEI_RS20165 ENOG41080XQ Signal transduction protein with cbs domains BWEI_RS20210 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BWEI_RS20225 ENOG410848D S4 domain protein YaaA BWEI_RS20230 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BWEI_RS20250 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BWEI_RS20280 ENOG4107QJE Chromosome Partitioning Protein BWEI_RS20285 ENOG4105FA0 parb-like partition protein BWEI_RS20290 ENOG4108ZDA Sporulation protein YyaC BWEI_RS20295 ENOG4105D8X mechanosensitive ion channel BWEI_RS20300 ENOG4105VDK protein, conserved in bacteria BWEI_RS20305 ENOG4105C3G gtp-binding protein BWEI_RS20315 ENOG4108UUM single-stranded DNA-binding protein BWEI_RS20325 ENOG4108XMW Membrane BWEI_RS20330 ENOG4105BZR domain protein BWEI_RS20340 ENOG4105CDU Replicative dna helicase BWEI_RS20345 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BWEI_RS20370 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS20375 ENOG4105BZU Histidine kinase BWEI_RS20390 ENOG4105Q2H domain protein BWEI_RS20395 ENOG4105C0H protease BWEI_RS20415 ENOG4105DPN Oligoendopeptidase f BWEI_RS20430 ENOG4105C1J atp-dependent rna helicase BWEI_RS20440 ENOG4108UT2 hemolysin iii BWEI_RS20445 ENOG4105CMR udp-glucose 4-epimerase BWEI_RS20485 ENOG4105IW1 AmiS UreI transporter BWEI_RS20495 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BWEI_RS20510 ENOG4107RGD Major Facilitator superfamily BWEI_RS20515 ENOG4108HRK Histidine kinase BWEI_RS20520 ENOG4105DY9 regulatoR BWEI_RS20535 ENOG4106F5Q Membrane BWEI_RS20540 ENOG4105E0X reductase BWEI_RS20550 ENOG41067SE Tetr family transcriptional regulator BWEI_RS20555 ENOG4105C5H ABC transporter BWEI_RS20560 ENOG4107XI7 Tetr family transcriptional regulator BWEI_RS20570 ENOG4105CKK Glycosyl transferase, family 2 BWEI_RS20575 ENOG4105EJV Membrane BWEI_RS20585 ENOG4105K64 Glycosyl transferase, family 2 BWEI_RS20595 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BWEI_RS20600 ENOG4108S4H thioesterase Superfamily protein BWEI_RS20610 ENOG4106YBV Methyl-accepting chemotaxis BWEI_RS20615 ENOG4105EN6 Membrane BWEI_RS20635 ENOG41079KZ Major Facilitator Superfamily BWEI_RS20640 ENOG4105DY9 regulatoR BWEI_RS20645 ENOG4105D22 carbon starvation protein BWEI_RS20650 ENOG4105VCD cytoplasmic protein BWEI_RS20655 ENOG4105BZU Histidine kinase BWEI_RS20660 ENOG4105DWF phosphomethylpyrimidine kinase BWEI_RS20665 ENOG4105BZU Histidine kinase BWEI_RS20670 ENOG4105WH1 Two component transcriptional regulator luxr family BWEI_RS20680 ENOG4108Y4K DNA-binding transcriptional activator BWEI_RS20705 ENOG4105D6E homoserine dehydrogenase BWEI_RS20720 ENOG41090WU lipolytic protein G-D-S-L family BWEI_RS20725 ENOG4105CJ1 ABC, transporter BWEI_RS20730 ENOG4108TU7 Inherit from COG: (ABC) transporter BWEI_RS20740 ENOG4105VCH membrane BWEI_RS20745 ENOG410667J hydrolase BWEI_RS20775 ENOG4108VKI Cell wall hydrolase BWEI_RS20790 ENOG4108IJ2 phosphate acetyltransferase BWEI_RS20795 ENOG4105JGI Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity) BWEI_RS20800 ENOG4108VCI transcription factor, rsfa family BWEI_RS20810 ENOG4105DQ5 transport system permease protein BWEI_RS20815 ENOG4105EHG Permease protein BWEI_RS20820 ENOG4105E0A ABC, transporter BWEI_RS20825 ENOG4108MES Periplasmic binding protein BWEI_RS20830 ENOG4105DCI Phosphohydrolase BWEI_RS20835 ENOG41069HH 4-oxalocrotonate tautomerase BWEI_RS20840 ENOG4108Z4T Peptidase M50 BWEI_RS20845 ENOG4108XFG YwhD family BWEI_RS20850 ENOG4105BZ4 penicillin-binding protein BWEI_RS20855 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BWEI_RS20860 ENOG4107SWG transcriptional regulator MERR family BWEI_RS20865 ENOG4105DXB Major Facilitator superfamily BWEI_RS20875 ENOG4105CYW agmatinase BWEI_RS20895 ENOG410684U Domain of unknown function (DUF1934) BWEI_RS20915 ENOG4105IIU Aminopeptidase BWEI_RS20920 ENOG4106A4F Removes the N-terminal methionine from nascent proteins (By similarity) BWEI_RS20925 ENOG4108M15 ABC transporter BWEI_RS20930 ENOG4105KCT ABC transporter BWEI_RS20935 ENOG4105BZU Histidine kinase BWEI_RS20945 ENOG4105D4Y metalloprotease BWEI_RS20960 ENOG4105BZU Histidine kinase BWEI_RS20975 ENOG4105DF6 Fe-S oxidoreductase BWEI_RS20985 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BWEI_RS20990 ENOG4105C1G acyl-Coa dehydrogenase BWEI_RS20995 ENOG4105C1G acyl-Coa dehydrogenase BWEI_RS21030 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BWEI_RS21035 ENOG4105CBT Fructose-1,6-bisphosphatase BWEI_RS21040 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BWEI_RS21065 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BWEI_RS21070 ENOG4108ZXQ stage ii sporulation protein r BWEI_RS21080 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BWEI_RS21095 ENOG4107XC4 flavin reductase domain protein, FMN-binding BWEI_RS21100 ENOG4108VGI doxx family BWEI_RS21115 ENOG4108YZG isomerase BWEI_RS21150 ENOG4107RFS it plays a direct role in the translocation of protons across the membrane (By similarity) BWEI_RS21195 ENOG4105D7V transposase BWEI_RS21205 ENOG4105BZU Histidine kinase BWEI_RS21220 ENOG4105CYU NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain BWEI_RS21250 ENOG4105D65 subunit l BWEI_RS21255 ENOG4105C8S subunit m BWEI_RS21260 ENOG4105CNR NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BWEI_RS21265 ENOG4106778 Protein of unknown function (DUF1146) BWEI_RS21305 ENOG4105DY9 regulatoR BWEI_RS21320 ENOG4105FRN stage II sporulation protein BWEI_RS21330 ENOG4105MT0 Sporulation transcriptional regulator spoiiid BWEI_RS21345 ENOG4107YJ4 chain length determinant protein BWEI_RS21350 ENOG4105HTX biosynthesis protein BWEI_RS21355 ENOG4107YJ4 chain length determinant protein BWEI_RS21360 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BWEI_RS21365 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BWEI_RS21370 ENOG4105D3Q Sugar transferase BWEI_RS21375 ENOG4105C6Y Udp-glucose 6-dehydrogenase BWEI_RS21415 ENOG4108KGH TRANSCRIPTIONal BWEI_RS21425 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS21430 ENOG41062D9 Histidine kinase BWEI_RS21445 ENOG4105CXY transporter BWEI_RS21470 ENOG4105C19 ABC transporter BWEI_RS21475 ENOG4107RBB ABC transporter, permease BWEI_RS21485 ENOG4105DMD Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS21515 ENOG4105C0D helicase BWEI_RS21520 ENOG4105KBK Zinc finger, swim domain protein BWEI_RS21545 ENOG41069ER domain protein BWEI_RS21550 ENOG4105C94 Transporter BWEI_RS21555 ENOG4107R8N Glycosyl transferase, family 2 BWEI_RS21580 ENOG4105E0M Sulfatase BWEI_RS21590 ENOG4105HYT Uncharacterized metal-binding protein (DUF2227) BWEI_RS21600 ENOG4105DAA L-lactate BWEI_RS21630 ENOG4107RSM transcriptional regulator BWEI_RS21635 ENOG4105ECB domain protein BWEI_RS21655 ENOG4105VZJ PTS System BWEI_RS21665 ENOG4105VCP PTS System BWEI_RS21670 ENOG4105X3E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity) BWEI_RS21675 ENOG4108JPV Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity) BWEI_RS21685 ENOG4105CK1 PTS System BWEI_RS21690 ENOG4105VCP PTS System BWEI_RS21695 ENOG4105F8D glycoside hydrolase family 4 BWEI_RS21715 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BWEI_RS21725 ENOG4105ESV Glycosyl transferase, family 4 BWEI_RS21730 ENOG4105C6Y Udp-glucose 6-dehydrogenase BWEI_RS21735 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BWEI_RS21740 ENOG4108KGH TRANSCRIPTIONal BWEI_RS21745 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BWEI_RS21755 ENOG4105KVH Transcriptional regulator BWEI_RS21770 ENOG41081UC Inherit from COG: Competence protein BWEI_RS21775 ENOG4105VEQ Cold shock protein BWEI_RS21805 ENOG4105CAK Cell division ATP-binding protein ftsE BWEI_RS21810 ENOG4105CRP Part of the ABC transporter FtsEX involved in BWEI_RS21815 ENOG4105CN1 protease BWEI_RS21825 ENOG4105BZ1 (ABC) transporter BWEI_RS21840 ENOG4108WS4 fmn reductase BWEI_RS21845 ENOG4108Z6Z Transcriptional regulator BWEI_RS21850 ENOG4105DUM transcriptional regulator, lysR family BWEI_RS21885 ENOG4107TXC Transcriptional regulator BWEI_RS21905 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BWEI_RS21920 ENOG41086DT Membrane protein of unknown function BWEI_RS21940 ENOG4108S4C acetyltransferase BWEI_RS21950 ENOG4105C3M thioredoxin reductase BWEI_RS21960 ENOG4108Z4K mutator MutT protein BWEI_RS21970 ENOG4105CHW UPF0052 protein BWEI_RS21980 ENOG4105KRI phosphocarrier protein (HPr BWEI_RS21990 ENOG4108QY0 Membrane BWEI_RS22005 ENOG4105CZ3 stage V sporulation protein ad BWEI_RS22010 ENOG41090VF Stage v sporulation protein ac BWEI_RS22035 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BWEI_RS22075 ENOG4105DU0 nucleoside hydrolase BWEI_RS22085 ENOG41067MG lrgb family BWEI_RS22090 ENOG4105XZU Preprotein translocase, subunit SecG BWEI_RS22100 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BWEI_RS22110 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS22125 ENOG4105CM4 permease protein BWEI_RS22130 ENOG4108IPW abc transporter atp-binding protein BWEI_RS22145 ENOG4108V7B Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity) BWEI_RS22150 ENOG4108V2W Carbonate dehydratase BWEI_RS22170 ENOG4108MK9 spermidine N(1)-acetyltransferase BWEI_RS22185 ENOG4105WMR Protein CrcB homolog BWEI_RS22190 ENOG4105WMR Protein CrcB homolog BWEI_RS22200 ENOG4105C8Q Methyl-accepting chemotaxis BWEI_RS22210 ENOG4105D4A Cell wall formation (By similarity) BWEI_RS22215 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BWEI_RS22230 ENOG4105KVH Transcriptional regulator BWEI_RS22235 ENOG4105F27 Major Facilitator BWEI_RS22240 ENOG4105CV8 reductase BWEI_RS22255 ENOG4108RYK Nad-dependent epimerase dehydratase BWEI_RS22270 ENOG4105D9N nucleoside BWEI_RS22275 ENOG4105D9N nucleoside BWEI_RS22285 ENOG41090A1 ferritin BWEI_RS22295 ENOG4108URH decarboxylase BWEI_RS22320 ENOG4108RMU ferritin dps family protein BWEI_RS22330 ENOG4105NCW Trka-c domain protein BWEI_RS22335 ENOG4107S91 Sodium hydrogen exchanger BWEI_RS22355 ENOG4105D4Y metalloprotease BWEI_RS22360 ENOG4105VG1 fes assembly suf system protein BWEI_RS22365 ENOG4105C8Q Methyl-accepting chemotaxis BWEI_RS22370 ENOG4105C8Q Methyl-accepting chemotaxis BWEI_RS22390 ENOG4105BZU Histidine kinase BWEI_RS22395 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS22400 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BWEI_RS22410 ENOG4107ZTW SNARE associated Golgi BWEI_RS22435 ENOG4107AYK membrAne BWEI_RS22445 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BWEI_RS22455 ENOG4107R7I amino acid BWEI_RS22460 ENOG4108SUT Major Facilitator Superfamily BWEI_RS22470 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BWEI_RS22490 ENOG4105DZ1 carboxypeptidase BWEI_RS22500 ENOG4105CHU acetyl-coa acetyltransferase BWEI_RS22505 ENOG4105C1G acyl-Coa dehydrogenase BWEI_RS22510 ENOG4108W8B Beta-lactamase domain protein BWEI_RS22580 ENOG41080E8 Transcriptional regulator, Spx MgsR family BWEI_RS22615 ENOG4108UMI ABC transporter, permease BWEI_RS22620 ENOG4105D01 (LipO)protein BWEI_RS22625 ENOG4105D01 (LipO)protein BWEI_RS22630 ENOG4105C3K feS assembly ATPase SufC BWEI_RS22635 ENOG4105JRK feS assembly protein SufD BWEI_RS22640 ENOG4105C9B Cysteine desulfurase BWEI_RS22645 ENOG4108UNV SUF system FeS assembly protein, NifU family BWEI_RS22650 ENOG4105DIW FeS assembly protein SUFB BWEI_RS22655 ENOG4107R8B 5'-nucleotidase BWEI_RS22660 ENOG4105KZD Domain of unknown function (DUF1805) BWEI_RS22665 ENOG4108YTE sporulation protein YunB BWEI_RS22670 ENOG4105FAA peptidase M23 BWEI_RS22695 ENOG41090T1 Membrane BWEI_RS22700 ENOG4107TXC Transcriptional regulator BWEI_RS22705 ENOG4106EGE Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) BWEI_RS22710 ENOG4105MMD transcriptional regulator BWEI_RS22730 ENOG4105CBT Fructose-1,6-bisphosphatase BWEI_RS22745 ENOG4105D4U had-superfamily hydrolase, subfamily iia BWEI_RS22755 ENOG4105DYS nad(p)h dehydrogenase (quinone) BWEI_RS22775 ENOG4108W5N phosphatidylglycerophosphatase a BWEI_RS22790 ENOG41083MR nifu domain-containing protein BWEI_RS22820 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BWEI_RS22825 ENOG4105C4B ABC transporter, permease BWEI_RS22850 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BWEI_RS22870 ENOG4105EWC Purine nucleoside phosphorylase BWEI_RS22895 ENOG4105CEP NADH dehydrogenase BWEI_RS22910 ENOG41069ER domain protein BWEI_RS22930 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BWEI_RS22945 ENOG4105KA0 thioesterase Superfamily protein BWEI_RS22965 ENOG4107R3E Citrate transporter BWEI_RS22975 ENOG4105Y38 Kinase-associated protein B BWEI_RS22985 ENOG4105C87 Aminotransferase class I and II BWEI_RS22995 ENOG4108MUZ hydrolase BWEI_RS23000 ENOG4105C5I Dehydrogenase BWEI_RS23005 ENOG4108ZB6 transcriptional regulator AsnC family BWEI_RS23010 ENOG4105CHM Aminotransferase BWEI_RS23020 ENOG4105WG9 Conserved Protein BWEI_RS23035 ENOG4107PBV potassium channel BWEI_RS23040 ENOG4105KT7 mgtC SapB transporter BWEI_RS23055 ENOG4105E2Z phosphate ABC transporter (Permease BWEI_RS23060 ENOG4105C8U phosphate abc transporter BWEI_RS23065 ENOG4105CVA phosphate BWEI_RS23075 ENOG4105CE1 Ferrous iron transport protein b BWEI_RS23080 ENOG4105CE1 Ferrous iron transport protein b BWEI_RS23085 ENOG4108NHD germination protein BWEI_RS23100 ENOG4105E1V na solute symporter BWEI_RS23105 ENOG4106CAD Protein of unknown function (DUF3311) BWEI_RS23120 ENOG4108IQI permease BWEI_RS23125 ENOG4105E2S oxidase) subunit II BWEI_RS23130 ENOG4105BZ9 Cytochrome C oxidase, subunit I BWEI_RS23135 ENOG4105CCU oxidase (Subunit III) BWEI_RS23155 ENOG4105MA6 gCN5-related N-acetyltransferase BWEI_RS23170 ENOG4105C7N Xanthine uracil vitamin C permease BWEI_RS23175 ENOG4105C85 amino acid BWEI_RS23195 ENOG4105DUX Transporter BWEI_RS23215 ENOG4105VZ8 Transcriptional regulator BWEI_RS23220 ENOG41069ER domain protein BWEI_RS23225 ENOG4107WTJ Methyl-accepting chemotaxis sensory transducer BWEI_RS23230 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BWEI_RS23255 ENOG4108QYW Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity) BWEI_RS23275 ENOG4105C6X Major Facilitator BWEI_RS23300 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BWEI_RS23305 ENOG4105CNN ABC, transporter BWEI_RS23310 ENOG4105C2J ABC transporter BWEI_RS23320 ENOG4108RVA ribokinase BWEI_RS23325 ENOG4105ETE Transcriptional regulator (LacI family BWEI_RS23330 ENOG4105C0R drug resistance transporter emrb qaca subfamily BWEI_RS23335 ENOG41067TZ transcriptional regulator, MarR family BWEI_RS23340 ENOG4105CXY transporter BWEI_RS23350 ENOG4108JQ7 (ABC) transporter BWEI_RS23355 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BWEI_RS23370 ENOG41068KF Universal stress protein BWEI_RS23375 ENOG4105CHH sulfate transporter BWEI_RS23385 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS23390 ENOG4105BZU Histidine kinase BWEI_RS23395 ENOG4105NAE bifunctional deaminase-reductase domain protein BWEI_RS23400 ENOG4105D29 Helix-turn-helix type 11 domain protein BWEI_RS23425 ENOG4108IQI permease BWEI_RS23430 ENOG4105DRP amino acid AbC transporter BWEI_RS23435 ENOG4105EAD ABC transporter BWEI_RS23440 ENOG4105CT1 (ABC) transporter BWEI_RS23445 ENOG4105CDA abc transporter atp-binding protein BWEI_RS23450 ENOG4105BZG amino acid carrier protein BWEI_RS23455 ENOG4105CRN Aminoglycoside phosphotransferase BWEI_RS23470 ENOG4105EY9 peptidase S8 and S53, subtilisin, kexin, sedolisin BWEI_RS23475 ENOG4105WH1 Two component transcriptional regulator luxr family BWEI_RS23480 ENOG4108XG2 Histidine kinase BWEI_RS23485 ENOG4105E1K spore germination protein BWEI_RS23500 ENOG4105CG3 alpha amylase, catalytic region BWEI_RS23505 ENOG4105C5Y PTS System BWEI_RS23510 ENOG4107414 GntR family transcriptional regulator BWEI_RS23515 ENOG4105D5Q Arginine ornithine antiporter BWEI_RS23520 ENOG4105BZU Histidine kinase BWEI_RS23530 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BWEI_RS23535 ENOG4105GMT ATPase associated with various cellular activities aaa_5 BWEI_RS23540 ENOG4107T89 von Willebrand factor, type A BWEI_RS23550 ENOG4105EXW epimerase dehydratase BWEI_RS23560 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BWEI_RS23565 ENOG4105E0A ABC, transporter BWEI_RS23570 ENOG4108IHU transport system permease protein BWEI_RS23575 ENOG4105DQ5 transport system permease protein BWEI_RS23580 ENOG4108MES Periplasmic binding protein BWEI_RS23585 ENOG4105DUX Transporter BWEI_RS23600 ENOG4107QXG alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BWEI_RS23605 ENOG4105DAA L-lactate BWEI_RS23610 ENOG4108IJ0 Aspartate ammonia-lyase BWEI_RS23615 ENOG4105C37 (CBS) domain BWEI_RS23620 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BWEI_RS23625 ENOG4105D9N nucleoside BWEI_RS23630 ENOG4108KGH TRANSCRIPTIONal BWEI_RS23635 ENOG41073R8 VanW family BWEI_RS23665 ENOG4105DAP Nicotinate phosphoribosyltransferase BWEI_RS23670 ENOG4105C59 p-type ATPase BWEI_RS23685 ENOG4105CUB amino acid BWEI_RS23705 ENOG4108JB9 formate dehydrogenase BWEI_RS23710 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BWEI_RS23715 ENOG4108RTV Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity) BWEI_RS23720 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BWEI_RS23725 ENOG4105BZU Histidine kinase BWEI_RS23735 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BWEI_RS23740 ENOG4108UZ3 Transporter BWEI_RS23750 ENOG4105C6K Malic enzyme BWEI_RS23760 ENOG4108MRH transcriptional regulatory protein BWEI_RS23785 ENOG4105US7 Histidine kinase BWEI_RS23790 ENOG4108STX response regulator BWEI_RS23795 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BWEI_RS23800 ENOG4105BZ7 extracellular solute-binding protein family 1 BWEI_RS23805 ENOG4105EX2 Binding-protein-dependent transport systems, inner membrane component BWEI_RS23810 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BWEI_RS23815 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BWEI_RS23820 ENOG4108ZIA glycerol-3-phosphate responsive antiterminator BWEI_RS23845 ENOG4105D4T Citrate transporter BWEI_RS23850 ENOG4108V9W transcriptional regulatory protein BWEI_RS23855 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BWEI_RS23865 ENOG4105DZ6 Band 7 protein BWEI_RS23890 ENOG4105CYN Serine protein kinase BWEI_RS23895 ENOG4105BZU Histidine kinase BWEI_RS23900 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BWEI_RS23910 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BWEI_RS23920 ENOG4107ZQN disulfide bond BWEI_RS23925 ENOG4108JQC penicillin-binding protein 1A BWEI_RS24125 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BWEI_RS24130 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BWEI_RS24135 ENOG4105C83 adenylosuccinate lyase BWEI_RS24145 ENOG4105VR9 phosphoribosylformylglycinamidine synthase BWEI_RS24170 ENOG4108V3E phosphoribosylglycinamide formyltransferase BWEI_RS24180 ENOG4105C12 Phosphoribosylglycinamide synthetase BWEI_RS24205 ENOG4105C4R Atp-dependent dna helicase BWEI_RS24230 ENOG4108W2Y isochorismatase BWEI_RS24240 ENOG4108UMI ABC transporter, permease BWEI_RS24245 ENOG4105D01 (LipO)protein BWEI_RS24260 ENOG41067TZ transcriptional regulator, MarR family BWEI_RS24265 ENOG4107I77 yiaA/B two helix domain BWEI_RS24285 ENOG4105CBD Diacylglycerol kinase BWEI_RS24295 ENOG4108JPW Aminotransferase BWEI_RS24305 ENOG4105C26 Dehydrogenase BWEI_RS24310 ENOG4105KPY Small multidrug resistance protein BWEI_RS24330 ENOG4105D9N nucleoside BWEI_RS24335 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BWEI_RS24345 ENOG4105BZU Histidine kinase BWEI_RS24350 ENOG4108W15 Protein of unknown function (DUF1456) BWEI_RS24365 ENOG4105DTQ mandelate racemase muconate lactonizing BWEI_RS24375 ENOG4105DFD Na H antiporter BWEI_RS24395 ENOG4105D3R alkyl hydroperoxide reductase BWEI_RS24415 ENOG4105EHG Permease protein BWEI_RS24420 ENOG4105DQ5 transport system permease protein BWEI_RS24425 ENOG4108V5C ABC transporter BWEI_RS24445 ENOG4106UIA BWEI_RS24450 ENOG4106UIA BWEI_RS24465 ENOG4105BZU Histidine kinase BWEI_RS24485 ENOG410756H nucleotidyltransferase BWEI_RS24500 ENOG4105E5Q amino acid AbC transporter BWEI_RS24505 ENOG4105EAB amino acid AbC transporter BWEI_RS24515 ENOG4105C8Q Methyl-accepting chemotaxis BWEI_RS24530 ENOG4105DBV ornithine carbamoyltransferase BWEI_RS24540 ENOG4105C5B carbamate kinase BWEI_RS24555 ENOG4105DNP FAD linked oxidase domain protein BWEI_RS24565 ENOG4105CI1 PTS System BWEI_RS24580 ENOG4105C9U ATP-dependent DNA helicase RecQ BWEI_RS24595 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BWEI_RS24610 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BWEI_RS24615 ENOG4105D2X ABC transporter substrate-binding protein BWEI_RS24625 ENOG4105C5H ABC transporter BWEI_RS24650 ENOG41062JF Transcriptional regulator BWEI_RS24665 ENOG4105DEU major facilitator superfamily BWEI_RS24695 ENOG4108N0M stress protein BWEI_RS24700 ENOG4106FN3 tellurium resistance protein BWEI_RS24705 ENOG4106FN3 tellurium resistance protein BWEI_RS24710 ENOG4107TS3 membrane protein, TerC BWEI_RS24715 ENOG4108TTB tellurium resistance protein BWEI_RS24745 ENOG4107U9T Pfam:Ribonuclease_BN BWEI_RS24750 ENOG4105C59 p-type ATPase BWEI_RS24755 ENOG4108IPJ Membrane BWEI_RS24775 ENOG4107ZTW SNARE associated Golgi BWEI_RS24790 ENOG410606W general stress protein BWEI_RS24795 ENOG4105UPD Calcium Proton BWEI_RS24835 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BWEI_RS24845 ENOG4108JUB Transcriptional regulator BWEI_RS24855 ENOG4108IQI permease BWEI_RS24890 ENOG4108A04 Beta-lactamase BWEI_RS24910 ENOG4107R51 Glycosyl transferase, family 2 BWEI_RS24915 ENOG4107QQG Dehydrogenase BWEI_RS24920 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BWEI_RS24925 ENOG4105CKK Glycosyl transferase, family 2 BWEI_RS24940 ENOG4105F1A Pyruvate formate-lyase BWEI_RS24955 ENOG4105CI2 imidazolone-5-propionate hydrolase BWEI_RS24960 ENOG4105ECP epimerase BWEI_RS24985 ENOG41067AE Membrane-bound metal-dependent hydrolase BWEI_RS24990 ENOG4105CEN a g-specific adenine glycosylase BWEI_RS25010 ENOG4105BZ1 (ABC) transporter BWEI_RS25015 ENOG4107NBY Membrane BWEI_RS25020 ENOG4105CBC glutamate synthase BWEI_RS25030 ENOG4108IUW ABC transporter BWEI_RS25050 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BWEI_RS25055 ENOG4105G5W regulator Fur family BWEI_RS25080 ENOG4107ZXU DSBA oxidoreductase BWEI_RS25090 ENOG4108VK3 Cupin 2 Conserved Barrel Domain Protein BWEI_RS25095 ENOG4108BUD transposase BWEI_RS25120 ENOG4105W8Z 4'-phosphopantetheinyl transferase BWEI_RS25130 ENOG4105CHR reductase BWEI_RS25160 ENOG4108XZ3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity) BWEI_RS25170 ENOG4105U5Y Transcriptional regulator BWEI_RS25175 ENOG4105K4H Nlp p60 protein BWEI_RS25185 ENOG4105D8G Major Facilitator superfamily BWEI_RS25275 ENOG4108KXV response regulator BWEI_RS25280 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BWEI_RS25335 ENOG4105U5Y Transcriptional regulator BWEI_RS25350 ENOG4108BUD transposase BWEI_RS25360 ENOG4106PZP Bacillus haemolytic enterotoxin (HBL) BWEI_RS25380 ENOG4108BUD transposase BWEI_RS25410 ENOG4105D7V transposase BWEI_RS25420 ENOG4107HBJ phospholipase C BWEI_RS25435 ENOG4105D7V transposase BWEI_RS25500 ENOG4108UGV hypoxanthine phosphoribosyltransferase BWEI_RS25525 ENOG4108N23 SpoOM-related protein BWEI_RS25595 ENOG4105DG6 mannose-6-phosphate isomerase BWEI_RS25600 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BWEI_RS25605 ENOG4105C6Y Udp-glucose 6-dehydrogenase BWEI_RS25615 ENOG4108Z90 colanic acid biosynthesis acetyltransferase wcaF BWEI_RS25645 ENOG4105C0K Gdp-mannose 4,6-dehydratase BWEI_RS25650 ENOG4105C30 Nad-dependent epimerase dehydratase BWEI_RS25655 ENOG4105D3Q Sugar transferase BWEI_RS25660 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BWEI_RS25665 ENOG4108RB3 Capsular polysaccharide biosynthesis protein BWEI_RS25670 ENOG4107YJ4 chain length determinant protein BWEI_RS25675 ENOG4105HTX biosynthesis protein BWEI_RS25730 ENOG4105D7V transposase BWEI_RS25785 ENOG4105CHH sulfate transporter BWEI_RS25800 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BWEI_RS25825 ENOG4108BUD transposase BWEI_RS25900 ENOG4108YZM Toxic component of a toxin-antitoxin (TA) module (By similarity) BWEI_RS25915 ENOG4108SGW outer membrane lipoprotein-sorting protein-like protein BWEI_RS25940 ENOG4107EES Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity) BWEI_RS25945 ENOG4105CPF Cell wall formation (By similarity) BWEI_RS25950 ENOG4108SC4 )-transporter BWEI_RS25960 ENOG4105ERH Fumarylacetoacetate hydrolase BWEI_RS25965 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BWEI_RS25980 ENOG410667J hydrolase BWEI_RS25985 ENOG4108JQ7 (ABC) transporter BWEI_RS25990 ENOG4105C3U ABC transporter BWEI_RS25995 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BWEI_RS26020 ENOG4108KYE ABC-2 type transporter BWEI_RS26025 ENOG41090VJ ABC-2 type transporter BWEI_RS26030 ENOG4105CJ1 ABC, transporter BWEI_RS26035 ENOG4105WH1 Two component transcriptional regulator luxr family BWEI_RS26040 ENOG4105BZU Histidine kinase BWEI_RS26045 ENOG4105C5H ABC transporter BWEI_RS26065 ENOG4105I5R Uncharacterized protein conserved in bacteria (DUF2334) BWEI_RS26085 ENOG410749K Uncharacterized protein conserved in bacteria (DUF2179) BWEI_RS26100 ENOG4105F6E Acyl-transferase BWEI_RS26115 ENOG4105HD0 Transcriptional regulator of molybdate metabolism, LysR family BWEI_RS26120 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BWEI_RS26125 ENOG4105E0C molybdate abc transporter BWEI_RS26135 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BWEI_RS26140 ENOG4105II7 pyrroline-5-carboxylate reductase BWEI_RS26150 ENOG4108J59 Extracellular solute-binding protein, family 5 BWEI_RS26155 ENOG4108J59 Extracellular solute-binding protein, family 5 BWEI_RS26170 ENOG4108JQ7 (ABC) transporter BWEI_RS26175 ENOG4105C3U ABC transporter BWEI_RS26180 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BWEI_RS26185 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BWEI_RS26200 ENOG4105C2C drug resistance transporter, Bcr CflA BWEI_RS26215 ENOG4105IQ5 FAD linked oxidase domain protein BWEI_RS26230 ENOG4105D01 (LipO)protein BWEI_RS26240 ENOG4108UMI ABC transporter, permease BWEI_RS26245 ENOG4108PSK reductase BWEI_RS26270 ENOG4105DRY peptidase s9 prolyl oligopeptidase active site domain protein BWEI_RS26280 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BWEI_RS26290 ENOG4107U5W ybbr family BWEI_RS26295 ENOG4105C8B TIGR00159 family BWEI_RS26345 ENOG4108Z0C Uvrb UvrC protein BWEI_RS26360 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BWEI_RS26370 ENOG4105CTP PilT protein domain protein BWEI_RS26390 ENOG4105D7W serine acetyltransferase BWEI_RS26405 ENOG4105C2N RNA methyltransferase TrmH family group 3 BWEI_RS26410 ENOG4105M0M Tetracycline resistance protein BWEI_RS26415 ENOG4105QIV RNA polymerase BWEI_RS26425 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BWEI_RS26450 ENOG4107Y49 methyltransferase BWEI_RS26465 ENOG4105XPM ribosomal protein BWEI_RS26595 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BWEI_RS26605 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BWEI_RS26650 ENOG4105EK6 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity) BWEI_RS26655 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BWEI_RS26680 ENOG4105D1F ATP-binding protein BWEI_RS26695 ENOG4108NMV polysaccharide deacetylase BWEI_RS26710 ENOG4105CXN decarboxylase BWEI_RS26720 ENOG4105FA2 dna polymerase iii BWEI_RS26725 ENOG4105MA4 psp1 domain protein BWEI_RS26735 ENOG41060K3 Methyltransferase BWEI_RS26745 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BWEI_RS26750 ENOG4105KRN Transcriptional regulator, abrb family BWEI_RS26755 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BWEI_RS26760 ENOG4105F8V Hydrolase, tatD family BWEI_RS26765 ENOG4105HVR Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step (By similarity) BWEI_RS26775 ENOG4105XFA sporulation peptidase YabG BWEI_RS26780 ENOG4105W42 Veg protein BWEI_RS26795 ENOG4105DFT pur operon repressor BWEI_RS26800 ENOG4105KME endoribonuclease L-psp BWEI_RS26830 ENOG4108JA2 transcriptioN-repair coupling factor BWEI_RS26835 ENOG4108M14 stage v sporulation protein t BWEI_RS26845 ENOG4108IY2 MazG family BWEI_RS26850 ENOG41082I2 s4 domain protein BWEI_RS26855 ENOG4105VYY sporulation protein yabp BWEI_RS26870 ENOG41060GV RNA binding s1 domain protein BWEI_RS26890 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BWEI_RS26895 ENOG4108UGV hypoxanthine phosphoribosyltransferase BWEI_RS26900 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BWEI_RS26915 ENOG4105C6T cysteine synthase BWEI_RS26920 ENOG4105CRQ synthase (Component I) BWEI_RS26925 ENOG4105DDQ anthranilate synthase BWEI_RS26930 ENOG41082R7 4-amino-4-deoxychorismate lyase EC 4.1.3.38 BWEI_RS26935 ENOG4105EEI dihydropteroate synthase BWEI_RS26940 ENOG4105KRF dihydroneopterin aldolase BWEI_RS26945 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BWEI_RS26955 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BWEI_RS26975 ENOG4105BZU Histidine kinase BWEI_RS26985 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BWEI_RS27020 ENOG4108FQ0 the rest of the oligosaccharide is released intact. Cleaves the peptidoglycan connecting the daughter cells at the end of the cell division cycle, resulting in the separation of the two newly divided cells. Acts as an autolysin in penicillin-induced lysis BWEI_RS27055 ENOG4105CNU cell division protein FtsK BWEI_RS27090 ENOG4108BUD transposase BWEI_RS27170 ENOG4107R0E Glycosyl transferase, family 2 BWEI_RS27215 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BWEI_RS27255 ENOG41067XF inhibitor BWEI_RS27275 ENOG41088T4 Helicase IV BWEI_RS27310 ENOG4105FCD Major Facilitator BWEI_RS27360 ENOG4105KRN Transcriptional regulator, abrb family BWEI_RS27380 ENOG4105K8N protein family UPF0079, ATPase BWEI_RS27385 ENOG41072GX Peptidase M22 Glycoprotease BWEI_RS27390 ENOG410801F ribosomal-protein-alanine acetyltransferase BWEI_RS27400 ENOG4105C5H ABC transporter BWEI_RS27415 ENOG4108TYN CAAX amino terminal protease family protein BWEI_RS27435 ENOG4105C7N Xanthine uracil vitamin C permease BWEI_RS27445 ENOG4105BZU Histidine kinase BWEI_RS27455 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BWEI_RS27490 ENOG4105ZMH deoxynucleoside kinase BWEI_RS27500 ENOG4105GTG Isochorismatase BWEI_RS27505 ENOG4108Z6B deaminase BWEI_RS27510 ENOG4105C6E dna polymerase iii BWEI_RS27530 ENOG41067KS pro-sigma K processing BWEI_RS27605 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BWEI_RS27625 ENOG4108SHN Glycosyl transferase, family 2 BWEI_RS27635 ENOG4107QN2 dihydrolipoyl dehydrogenase BWEI_RS27645 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BWEI_RS27690 ENOG4105SX7 Transporter BWEI_RS27775 ENOG4105K64 Glycosyl transferase, family 2 BWEI_RS27815 ENOG410839T multidrug resistance protein BWEI_RS27850 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BWEI_RS28010 ENOG4107QQR Sporulation BWEI_RS28735 ENOG4105YAC BWEI_RS28845 ENOG4106AXD BWEI_RS28865 ENOG4105CMT Dihydroxyacetone kinase BWEI_RS29320 ENOG4105KNE Phosphatidate cytidylyltransferase BWEI_RS29760 ENOG4108BUD transposase