locus-tag	class	description
BWEI_RS00050	COG1404	Belongs to the peptidase S8 family
BWEI_RS00060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BWEI_RS00065	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWEI_RS00070	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BWEI_RS00080	COG0058	SHG alpha-glucan phosphorylase activity
BWEI_RS00090	COG0789	Transcriptional regulator
BWEI_RS00105	COG1278	Cold shock
BWEI_RS00110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BWEI_RS00115	COG1575	Belongs to the MenA family. Type 1 subfamily
BWEI_RS00120	COG1169	isochorismate synthase
BWEI_RS00125	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BWEI_RS00130	COG0596	Alpha beta hydrolase
BWEI_RS00135	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BWEI_RS00140	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS00145	COG4948	Mandelate Racemase Muconate Lactonizing
BWEI_RS00165	COG3964	amidohydrolase
BWEI_RS00185	COG2188	Transcriptional regulator
BWEI_RS00200	COG0577	efflux transmembrane transporter activity
BWEI_RS00205	COG1136	(ABC) transporter
BWEI_RS00210	COG0577	efflux transmembrane transporter activity
BWEI_RS00215	COG0577	efflux transmembrane transporter activity
BWEI_RS00220	COG2205	protein histidine kinase activity
BWEI_RS00225	COG0745	RESPONSE REGULATOR receiver
BWEI_RS00230	COG0640	Transcriptional regulator
BWEI_RS00235	COG5658	integral membrane protein
BWEI_RS00245	COG1131	(ABC) transporter
BWEI_RS00255	COG2207	Transcriptional regulator
BWEI_RS00255	COG3708	Transcriptional regulator
BWEI_RS00260	COG1136	(ABC) transporter
BWEI_RS00265	COG0577	efflux transmembrane transporter activity
BWEI_RS00275	COG3963	phosphatidate phosphatase activity
BWEI_RS00280	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS00320	COG1597	lipid kinase activity
BWEI_RS00325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BWEI_RS00350	COG0745	RESPONSE REGULATOR receiver
BWEI_RS00355	COG5002	protein histidine kinase activity
BWEI_RS00360	COG3859	Proton-coupled thiamine transporter YuaJ
BWEI_RS00385	COG1842	Phage shock protein A
BWEI_RS00410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS00425	COG1294	oxidase, subunit
BWEI_RS00430	COG1271	oxidase subunit
BWEI_RS00435	COG0288	reversible hydration of carbon dioxide
BWEI_RS00445	COG1854	S-ribosylhomocysteine lyase activity
BWEI_RS00450	COG0789	Transcriptional regulator
BWEI_RS00460	COG2076	Multidrug Resistance protein
BWEI_RS00500	COG0494	nUDIX hydrolase
BWEI_RS00520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWEI_RS00525	COG1116	anion transmembrane transporter activity
BWEI_RS00530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWEI_RS00555	COG1368	sulfuric ester hydrolase activity
BWEI_RS00560	COG2267	carboxylic ester hydrolase activity
BWEI_RS00565	COG0753	catalase activity
BWEI_RS00570	COG3852	Histidine kinase
BWEI_RS00575	COG5002	protein histidine kinase activity
BWEI_RS00615	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BWEI_RS00620	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BWEI_RS00640	COG0746	molybdenum cofactor guanylyltransferase activity
BWEI_RS00645	COG0438	transferase activity, transferring glycosyl groups
BWEI_RS00650	COG0671	phosphoesterase, PA-phosphatase related
BWEI_RS00655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BWEI_RS00660	COG2267	carboxylic ester hydrolase activity
BWEI_RS00675	COG1794	racemase activity, acting on amino acids and derivatives
BWEI_RS00685	COG1131	(ABC) transporter
BWEI_RS00690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BWEI_RS00695	COG1242	4 iron, 4 sulfur cluster binding
BWEI_RS00715	COG1136	(ABC) transporter
BWEI_RS00725	COG0582	viral genome integration into host DNA
BWEI_RS00730	COG0490	domain, Protein
BWEI_RS00735	COG0475	glutathione-regulated potassium exporter activity
BWEI_RS00740	COG2814	Major facilitator Superfamily
BWEI_RS00745	COG0495	leucyl-tRNA aminoacylation
BWEI_RS00785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BWEI_RS00795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS00820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BWEI_RS00825	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWEI_RS00830	COG0315	cyclic pyranopterin monophosphate synthase activity
BWEI_RS00835	COG0303	'Molybdopterin
BWEI_RS00840	COG1763	Mo-molybdopterin cofactor biosynthetic process
BWEI_RS00845	COG0314	molybdopterin synthase activity
BWEI_RS00870	COG1329	Transcriptional regulator
BWEI_RS00890	COG3832	glyoxalase III activity
BWEI_RS00900	COG2814	Major facilitator Superfamily
BWEI_RS00905	COG2081	HI0933 family
BWEI_RS00910	COG2244	polysaccharide biosynthetic process
BWEI_RS00915	COG1187	pseudouridine synthase activity
BWEI_RS00920	COG1349	DNA-binding transcription factor activity
BWEI_RS00925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWEI_RS00935	COG1523	belongs to the glycosyl hydrolase 13 family
BWEI_RS00940	COG0510	thiamine kinase activity
BWEI_RS00950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BWEI_RS00955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS00965	COG1363	Peptidase, m42
BWEI_RS00970	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BWEI_RS00975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS00980	COG4848	Belongs to the UPF0354 family
BWEI_RS00985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWEI_RS01000	COG1674	ftsk spoiiie
BWEI_RS01010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BWEI_RS01020	COG1695	Transcriptional regulator
BWEI_RS01040	COG2309	aminopeptidase activity
BWEI_RS01050	COG3118	belongs to the thioredoxin family
BWEI_RS01055	COG4851	CamS sex pheromone cAM373 precursor
BWEI_RS01065	COG1609	Transcriptional regulator
BWEI_RS01080	COG1970	mechanosensitive ion channel activity
BWEI_RS01090	COG0666	response to abiotic stimulus
BWEI_RS01100	COG0745	RESPONSE REGULATOR receiver
BWEI_RS01115	COG0123	including yeast histone deacetylase and acetoin utilization protein
BWEI_RS01120	COG0517	IMP dehydrogenase activity
BWEI_RS01125	COG0454	-acetyltransferase
BWEI_RS01130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWEI_RS01135	COG0110	maltose O-acetyltransferase activity
BWEI_RS01145	COG1595	DNA-templated transcription, initiation
BWEI_RS01170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BWEI_RS01180	COG0626	cystathionine gamma-synthase activity
BWEI_RS01185	COG1956	GAF domain-containing protein
BWEI_RS01190	COG1309	transcriptional regulator
BWEI_RS01200	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BWEI_RS01205	COG1104	cysteine desulfurase activity
BWEI_RS01220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWEI_RS01230	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BWEI_RS01245	COG3874	Sporulation protein YtfJ
BWEI_RS01250	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BWEI_RS01255	COG0827	DNA restriction-modification system
BWEI_RS01260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BWEI_RS01280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS01295	COG0137	argininosuccinate synthase activity
BWEI_RS01300	COG0165	Argininosuccinate lyase
BWEI_RS01320	COG0589	response to stress
BWEI_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS01340	COG1476	TRANSCRIPTIONal
BWEI_RS01350	COG0662	Cupin 2, conserved barrel domain protein
BWEI_RS01385	COG0006	proline dipeptidase activity
BWEI_RS01390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BWEI_RS01395	COG4109	DRTGG domain
BWEI_RS01410	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BWEI_RS01425	COG0587	DNA-directed DNA polymerase activity
BWEI_RS01430	COG0281	malic enzyme
BWEI_RS01435	COG1725	Transcriptional regulator
BWEI_RS01440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BWEI_RS01450	COG0205	6-phosphofructokinase activity
BWEI_RS01460	COG3030	protein affecting phage T7 exclusion by the F plasmid
BWEI_RS01465	COG0628	permease
BWEI_RS01475	COG0372	Belongs to the citrate synthase family
BWEI_RS01480	COG0538	isocitrate dehydrogenase activity
BWEI_RS01485	COG0039	L-malate dehydrogenase activity
BWEI_RS01500	COG0745	RESPONSE REGULATOR receiver
BWEI_RS01505	COG5002	protein histidine kinase activity
BWEI_RS01510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWEI_RS01510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWEI_RS01520	COG1971	Probably functions as a manganese efflux pump
BWEI_RS01525	COG0237	dephospho-CoA kinase activity
BWEI_RS01530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWEI_RS01535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BWEI_RS01540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWEI_RS01545	COG3611	Membrane attachment protein
BWEI_RS01550	COG1484	DNA-dependent DNA replication
BWEI_RS01560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BWEI_RS01575	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BWEI_RS01585	COG1363	Peptidase, m42
BWEI_RS01590	COG1309	transcriptional regulator
BWEI_RS01595	COG1566	PFAM secretion protein HlyD family protein
BWEI_RS01600	COG2814	Major facilitator Superfamily
BWEI_RS01630	COG1418	mRNA catabolic process
BWEI_RS01640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWEI_RS01645	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BWEI_RS01665	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BWEI_RS01670	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BWEI_RS01675	COG1286	toxin biosynthetic process
BWEI_RS01680	COG1796	DNA polymerase
BWEI_RS01680	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWEI_RS01685	COG1193	negative regulation of DNA recombination
BWEI_RS01695	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS01700	COG5386	Cell surface protein
BWEI_RS01705	COG5386	Cell surface protein
BWEI_RS01720	COG1120	ATPase activity
BWEI_RS01725	COG4509	Sortase family
BWEI_RS01730	COG2329	Antibiotic biosynthesis monooxygenase
BWEI_RS01735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BWEI_RS01740	COG4895	conserved protein (DUF2196)
BWEI_RS01745	COG0745	RESPONSE REGULATOR receiver
BWEI_RS01750	COG2205	protein histidine kinase activity
BWEI_RS01755	COG1131	(ABC) transporter
BWEI_RS01780	COG2318	DinB family
BWEI_RS01800	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS01805	COG1309	transcriptional regulator
BWEI_RS01810	COG1024	Enoyl-CoA hydratase
BWEI_RS01815	COG2086	electron transfer activity
BWEI_RS01820	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BWEI_RS01825	COG3118	belongs to the thioredoxin family
BWEI_RS01830	COG0322	excinuclease ABC activity
BWEI_RS01835	COG1719	4-vinyl reductase, 4VR
BWEI_RS01840	COG2009	succinate dehydrogenase
BWEI_RS01845	COG1053	succinate dehydrogenase
BWEI_RS01850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BWEI_RS01855	COG0824	Thioesterase
BWEI_RS01860	COG1876	peptidase activity
BWEI_RS01865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWEI_RS01870	COG1360	Flagellar Motor Protein
BWEI_RS01875	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
BWEI_RS01880	COG4152	abc transporter atp-binding protein
BWEI_RS01885	COG1668	transmembrane transport
BWEI_RS01890	COG1959	2 iron, 2 sulfur cluster binding
BWEI_RS01900	COG0697	spore germination
BWEI_RS01905	COG1396	sequence-specific DNA binding
BWEI_RS01910	COG1983	PspC domain protein
BWEI_RS01915	COG0402	S-adenosylhomocysteine deaminase activity
BWEI_RS01920	COG2233	PERMEase
BWEI_RS01925	COG2197	response regulator
BWEI_RS01935	COG5401	PFAM Sporulation and spore germination
BWEI_RS01940	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BWEI_RS01950	COG0622	Phosphoesterase
BWEI_RS01975	COG0544	peptidyl-prolyl cis-trans isomerase activity
BWEI_RS01985	COG1067	ATP-dependent peptidase activity
BWEI_RS01985	COG0470	DNA polymerase III
BWEI_RS01995	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BWEI_RS02000	COG1764	response to oxidative stress
BWEI_RS02005	COG1846	Transcriptional regulator
BWEI_RS02010	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BWEI_RS02015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWEI_RS02020	COG0181	hydroxymethylbilane synthase activity
BWEI_RS02025	COG1587	Uroporphyrinogen-III synthase
BWEI_RS02030	COG0113	porphobilinogen synthase activity
BWEI_RS02035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BWEI_RS02040	COG1388	LysM domain
BWEI_RS02055	COG0285	dihydrofolate synthase activity
BWEI_RS02065	COG0424	maF-like protein
BWEI_RS02070	COG2003	Belongs to the UPF0758 family
BWEI_RS02075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWEI_RS02115	COG1484	DNA-dependent DNA replication
BWEI_RS02155	COG0582	viral genome integration into host DNA
BWEI_RS02195	COG1802	Transcriptional regulator
BWEI_RS02195	COG4626	Terminase
BWEI_RS02205	COG0740	serine-type endopeptidase activity
BWEI_RS02305	COG5632	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS02330	COG2003	Belongs to the UPF0758 family
BWEI_RS02335	COG1077	Cell shape determining protein MreB Mrl
BWEI_RS02350	COG0850	regulation of cytokinetic process
BWEI_RS02355	COG2894	cell division
BWEI_RS02360	COG0739	heme binding
BWEI_RS02365	COG1994	Peptidase M50
BWEI_RS02370	COG1530	ribonuclease E activity
BWEI_RS02380	COG2868	ribosomal protein
BWEI_RS02390	COG3290	protein histidine kinase activity
BWEI_RS02395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BWEI_RS02400	COG0745	RESPONSE REGULATOR receiver
BWEI_RS02405	COG5002	protein histidine kinase activity
BWEI_RS02410	COG1136	(ABC) transporter
BWEI_RS02415	COG0577	efflux transmembrane transporter activity
BWEI_RS02420	COG0577	efflux transmembrane transporter activity
BWEI_RS02425	COG0077	Prephenate dehydratase
BWEI_RS02430	COG2258	MOSC domain
BWEI_RS02435	COG1827	regulation of RNA biosynthetic process
BWEI_RS02440	COG1104	cysteine desulfurase activity
BWEI_RS02445	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BWEI_RS02450	COG0157	Belongs to the NadC ModD family
BWEI_RS02455	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BWEI_RS02480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BWEI_RS02485	COG0632	four-way junction helicase activity
BWEI_RS02490	COG2255	four-way junction helicase activity
BWEI_RS02505	COG0343	queuine tRNA-ribosyltransferase activity
BWEI_RS02510	COG1862	Preprotein translocase
BWEI_RS02520	COG2323	membrane
BWEI_RS02525	COG2244	polysaccharide biosynthetic process
BWEI_RS02535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWEI_RS02535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BWEI_RS02540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BWEI_RS02545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BWEI_RS02545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BWEI_RS02550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWEI_RS02555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWEI_RS02560	COG1490	D-aminoacyl-tRNA deacylase activity
BWEI_RS02575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BWEI_RS02580	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BWEI_RS02590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BWEI_RS02595	COG1959	2 iron, 2 sulfur cluster binding
BWEI_RS02600	COG1104	cysteine desulfurase activity
BWEI_RS02605	COG0482	sulfurtransferase activity
BWEI_RS02615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BWEI_RS02635	COG0628	permease
BWEI_RS02645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BWEI_RS02650	COG4472	Bacterial protein of unknown function (DUF965)
BWEI_RS02655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BWEI_RS02665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BWEI_RS02670	COG4122	O-methyltransferase activity
BWEI_RS02675	COG0826	peptidase U32
BWEI_RS02680	COG0826	peptidase U32
BWEI_RS02685	COG0572	uridine kinase
BWEI_RS02690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BWEI_RS02695	COG0768	penicillin binding
BWEI_RS02710	COG2226	methyltransferase
BWEI_RS02715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWEI_RS02720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWEI_RS02725	COG0626	cystathionine gamma-synthase activity
BWEI_RS02730	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS02730	COG1454	alcohol dehydrogenase
BWEI_RS02740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS02780	COG2259	Doxx family
BWEI_RS02785	COG2514	catechol 2,3-dioxygenase activity
BWEI_RS02790	COG2154	pterin-4-alpha-carbinolamine dehydratase
BWEI_RS02795	COG3186	Phenylalanine-4-hydroxylase
BWEI_RS02800	COG1404	Belongs to the peptidase S8 family
BWEI_RS02835	COG2267	carboxylic ester hydrolase activity
BWEI_RS02845	COG1785	Belongs to the alkaline phosphatase family
BWEI_RS02855	COG2357	RelA SpoT domain protein
BWEI_RS02860	COG1595	DNA-templated transcription, initiation
BWEI_RS02870	COG0688	phosphatidylethanolamine metabolic process
BWEI_RS02880	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BWEI_RS02885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BWEI_RS02890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BWEI_RS02895	COG1534	Rna-binding protein
BWEI_RS02900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BWEI_RS02905	COG1713	HD superfamily hydrolase involved in NAD metabolism
BWEI_RS02910	COG0799	negative regulation of ribosome biogenesis
BWEI_RS02915	COG2226	methyltransferase
BWEI_RS02920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWEI_RS02925	COG1596	polysaccharide export
BWEI_RS02925	COG1555	photosystem II stabilization
BWEI_RS02930	COG2131	deaminase
BWEI_RS02935	COG0658	competence protein
BWEI_RS02935	COG2333	competence protein COMEC
BWEI_RS02945	COG1466	dna polymerase III delta subunit
BWEI_RS02950	COG0268	Binds directly to 16S ribosomal RNA
BWEI_RS02955	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BWEI_RS02965	COG0481	GTPase activity
BWEI_RS02970	COG1733	regulation of RNA biosynthetic process
BWEI_RS02975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWEI_RS02980	COG1420	regulation of RNA biosynthetic process
BWEI_RS02990	COG0443	Heat shock 70 kDa protein
BWEI_RS02995	COG0484	heat shock protein binding
BWEI_RS03005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BWEI_RS03010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BWEI_RS03015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BWEI_RS03020	COG1610	YqeY-like protein
BWEI_RS03035	COG1702	phosphate starvation-inducible protein PhoH
BWEI_RS03040	COG1480	7TM receptor with intracellular HD hydrolase
BWEI_RS03045	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BWEI_RS03050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BWEI_RS03055	COG0295	cytidine deaminase activity
BWEI_RS03060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BWEI_RS03065	COG1381	Involved in DNA repair and RecF pathway recombination
BWEI_RS03070	COG0517	IMP dehydrogenase activity
BWEI_RS03075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BWEI_RS03080	COG0358	DNA primase activity
BWEI_RS03085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BWEI_RS03095	COG2384	SAM-dependent methyltransferase
BWEI_RS03100	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BWEI_RS03105	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BWEI_RS03120	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BWEI_RS03130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS03135	COG1121	(ABC) transporter
BWEI_RS03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWEI_RS03145	COG0735	belongs to the Fur family
BWEI_RS03150	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BWEI_RS03170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWEI_RS03175	COG0477	Major facilitator Superfamily
BWEI_RS03180	COG0768	penicillin binding
BWEI_RS03185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWEI_RS03190	COG0573	inorganic phosphate transmembrane transporter activity
BWEI_RS03195	COG0581	inorganic phosphate transmembrane transporter activity
BWEI_RS03205	COG0704	Plays a role in the regulation of phosphate uptake
BWEI_RS03210	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BWEI_RS03215	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWEI_RS03220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BWEI_RS03225	COG4483	Protein conserved in bacteria
BWEI_RS03230	COG1940	carbohydrate kinase activity
BWEI_RS03240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS03255	COG0626	cystathionine gamma-synthase activity
BWEI_RS03260	COG0626	cystathionine gamma-synthase activity
BWEI_RS03265	COG0646	methionine synthase
BWEI_RS03265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BWEI_RS03270	COG1410	methionine synthase
BWEI_RS03270	COG0646	methionine synthase
BWEI_RS03320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BWEI_RS03325	COG1459	type II secretion system
BWEI_RS03335	COG4970	Tfp pilus assembly protein FimT
BWEI_RS03360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BWEI_RS03385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWEI_RS03390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BWEI_RS03395	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWEI_RS03400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BWEI_RS03415	COG1725	Transcriptional regulator
BWEI_RS03450	COG2076	Multidrug Resistance protein
BWEI_RS03455	COG2076	Multidrug Resistance protein
BWEI_RS03465	COG1609	Transcriptional regulator
BWEI_RS03475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS03505	COG1321	iron dependent repressor
BWEI_RS03510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWEI_RS03520	COG3872	metal-dependent enzyme
BWEI_RS03530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BWEI_RS03535	COG0006	proline dipeptidase activity
BWEI_RS03540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BWEI_RS03560	COG3854	ATPases associated with a variety of cellular activities
BWEI_RS03600	COG0511	ligase activity, forming carbon-carbon bonds
BWEI_RS03605	COG0439	Biotin carboxylase
BWEI_RS03610	COG1302	Protein conserved in bacteria
BWEI_RS03615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWEI_RS03620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BWEI_RS03625	COG1570	exodeoxyribonuclease VII activity
BWEI_RS03630	COG1722	exodeoxyribonuclease VII activity
BWEI_RS03635	COG0142	geranyltranstransferase activity
BWEI_RS03640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BWEI_RS03645	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BWEI_RS03650	COG1438	arginine binding
BWEI_RS03655	COG0497	DNA recombination
BWEI_RS03660	COG0750	zinc metalloprotease
BWEI_RS03665	COG0745	RESPONSE REGULATOR receiver
BWEI_RS03715	COG0584	glycerophosphoryl diester phosphodiesterase
BWEI_RS03725	COG3829	transcription factor binding
BWEI_RS03725	COG3290	protein histidine kinase activity
BWEI_RS03730	COG0280	phosphate acetyltransferase
BWEI_RS03740	COG3426	butyrate kinase activity
BWEI_RS03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWEI_RS03750	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BWEI_RS03755	COG0022	dehydrogenase e1 component
BWEI_RS03760	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWEI_RS03765	COG0772	Belongs to the SEDS family
BWEI_RS03770	COG2323	membrane
BWEI_RS03775	COG2816	NAD+ diphosphatase activity
BWEI_RS03785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS03790	COG0765	amino acid transport
BWEI_RS03795	COG1126	abc transporter atp-binding protein
BWEI_RS03800	COG4129	membrane
BWEI_RS03805	COG1376	ErfK ybiS ycfS ynhG family protein
BWEI_RS03815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS03820	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWEI_RS03845	COG1131	(ABC) transporter
BWEI_RS03875	COG1234	tRNA 3'-trailer cleavage
BWEI_RS03885	COG1760	l-serine dehydratase
BWEI_RS03890	COG1760	l-serine dehydratase
BWEI_RS03895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWEI_RS03900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS03905	COG0300	oxidoreductase activity
BWEI_RS03915	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BWEI_RS03950	COG1522	sequence-specific DNA binding
BWEI_RS03960	COG0737	Belongs to the 5'-nucleotidase family
BWEI_RS03965	COG1757	Na H antiporter
BWEI_RS03975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWEI_RS03985	COG0156	8-amino-7-oxononanoate synthase activity
BWEI_RS03990	COG1073	alpha beta
BWEI_RS03990	COG2226	methyltransferase
BWEI_RS03995	COG4106	trans-aconitate 2-methyltransferase activity
BWEI_RS04000	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BWEI_RS04015	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWEI_RS04015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BWEI_RS04020	COG0307	riboflavin synthase, alpha
BWEI_RS04025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWEI_RS04025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BWEI_RS04040	COG1073	alpha beta
BWEI_RS04045	COG0456	acetyltransferase
BWEI_RS04050	COG1609	Transcriptional regulator
BWEI_RS04055	COG2056	Na+-H+ antiporter family
BWEI_RS04060	COG0596	Alpha beta hydrolase
BWEI_RS04070	COG4085	toxin activity
BWEI_RS04070	COG0737	Belongs to the 5'-nucleotidase family
BWEI_RS04070	COG1525	nuclease
BWEI_RS04080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWEI_RS04080	COG0456	acetyltransferase
BWEI_RS04085	COG0656	L-ascorbic acid biosynthetic process
BWEI_RS04090	COG0667	Aldo Keto reductase
BWEI_RS04110	COG1300	Membrane
BWEI_RS04115	COG0735	belongs to the Fur family
BWEI_RS04125	COG4974	Belongs to the 'phage' integrase family
BWEI_RS04135	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BWEI_RS04150	COG0598	Magnesium transport protein CorA
BWEI_RS04165	COG1846	Transcriptional regulator
BWEI_RS04185	COG1131	(ABC) transporter
BWEI_RS04190	COG1725	Transcriptional regulator
BWEI_RS04195	COG1686	Belongs to the peptidase S11 family
BWEI_RS04215	COG0733	neurotransmitter:sodium symporter activity
BWEI_RS04240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWEI_RS04255	COG0697	spore germination
BWEI_RS04260	COG0561	phosphatase activity
BWEI_RS04265	COG4086	secreted protein
BWEI_RS04270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BWEI_RS04280	COG1547	Domain of unknown function (DUF309)
BWEI_RS04285	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BWEI_RS04290	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BWEI_RS04300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWEI_RS04305	COG0363	glucosamine-6-phosphate deaminase activity
BWEI_RS04310	COG2188	Transcriptional regulator
BWEI_RS04320	COG3711	transcriptional antiterminator
BWEI_RS04325	COG2190	(PTS) system
BWEI_RS04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS04325	COG1263	PTS System
BWEI_RS04350	COG0778	Nitroreductase
BWEI_RS04355	COG2199	diguanylate cyclase activity
BWEI_RS04365	COG2084	Dehydrogenase
BWEI_RS04380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BWEI_RS04385	COG0235	Class ii aldolase
BWEI_RS04390	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BWEI_RS04395	COG1850	ribulose-bisphosphate carboxylase activity
BWEI_RS04400	COG0436	Aminotransferase
BWEI_RS04405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BWEI_RS04410	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BWEI_RS04415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BWEI_RS04420	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS04425	COG1695	Transcriptional regulator
BWEI_RS04455	COG0183	Belongs to the thiolase family
BWEI_RS04460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BWEI_RS04500	COG3842	ATPase activity
BWEI_RS04505	COG0366	Alpha amylase catalytic
BWEI_RS04515	COG2182	Extracellular solute-binding protein
BWEI_RS04520	COG1175	transmembrane transport
BWEI_RS04525	COG3833	ABC-type maltose transport systems, permease component
BWEI_RS04530	COG1609	Transcriptional regulator
BWEI_RS04535	COG0436	Aminotransferase
BWEI_RS04545	COG2205	protein histidine kinase activity
BWEI_RS04555	COG3209	COG3209 Rhs family protein
BWEI_RS04565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BWEI_RS04575	COG2814	Major facilitator Superfamily
BWEI_RS04620	COG1408	metallophosphoesterase
BWEI_RS04625	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS04630	COG2200	EAL domain
BWEI_RS04645	COG4703	Protein of unknown function (DUF1797)
BWEI_RS04650	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BWEI_RS04660	COG0517	IMP dehydrogenase activity
BWEI_RS04665	COG0583	DNA-binding transcription factor activity
BWEI_RS04670	COG2171	N-acyltransferase activity
BWEI_RS04675	COG1473	amidohydrolase
BWEI_RS04685	COG0569	domain protein
BWEI_RS04690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BWEI_RS04695	COG5503	Protein of unknown function (DUF1447)
BWEI_RS04705	COG0561	phosphatase activity
BWEI_RS04720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BWEI_RS04725	COG0022	dehydrogenase e1 component
BWEI_RS04730	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWEI_RS04775	COG1982	Orn Lys Arg decarboxylase major
BWEI_RS04780	COG4476	Belongs to the UPF0223 family
BWEI_RS04785	COG4493	Belongs to the UPF0637 family
BWEI_RS04795	COG0483	inositol monophosphate 1-phosphatase activity
BWEI_RS04805	COG1217	gtp-binding protein TYPA
BWEI_RS04820	COG4896	Protein conserved in bacteria
BWEI_RS04830	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BWEI_RS04835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BWEI_RS04840	COG4838	Belongs to the UPF0358 family
BWEI_RS04845	COG0772	Belongs to the SEDS family
BWEI_RS04850	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BWEI_RS04855	COG1612	heme a metabolic process
BWEI_RS04860	COG0109	protoheme IX farnesyltransferase activity
BWEI_RS04885	COG3336	cytochrome c oxidase
BWEI_RS04895	COG2340	Cysteine-rich secretory protein family
BWEI_RS04910	COG0406	alpha-ribazole phosphatase activity
BWEI_RS04915	COG3679	Belongs to the UPF0342 family
BWEI_RS04920	COG4471	UPF0298 protein
BWEI_RS04930	COG0742	ribosomal rna small subunit methyltransferase
BWEI_RS04935	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BWEI_RS04940	COG3314	Sporulation integral membrane protein YlbJ
BWEI_RS04945	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWEI_RS04950	COG3480	Lon protease (S16) C-terminal proteolytic domain
BWEI_RS04955	COG1323	Belongs to the UPF0348 family
BWEI_RS04960	COG1399	metal-binding, possibly nucleic acid-binding protein
BWEI_RS04965	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BWEI_RS04975	COG0454	-acetyltransferase
BWEI_RS04980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWEI_RS04985	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BWEI_RS04990	COG0275	rRNA processing
BWEI_RS05000	COG0768	penicillin binding
BWEI_RS05005	COG0768	penicillin binding
BWEI_RS05010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BWEI_RS05015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWEI_RS05020	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BWEI_RS05025	COG0772	Belongs to the SEDS family
BWEI_RS05040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BWEI_RS05045	COG0849	cell division
BWEI_RS05050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWEI_RS05060	COG1191	sigma factor activity
BWEI_RS05065	COG1191	sigma factor activity
BWEI_RS05070	COG1873	PFAM PRC-barrel domain
BWEI_RS05080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BWEI_RS05085	COG1799	cell septum assembly
BWEI_RS05090	COG0762	integral membrane protein
BWEI_RS05095	COG2302	S4 RNA-binding domain
BWEI_RS05100	COG3599	regulation of cell shape
BWEI_RS05105	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BWEI_RS05115	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BWEI_RS05120	COG0564	pseudouridine synthase activity
BWEI_RS05125	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BWEI_RS05135	COG0540	Belongs to the ATCase OTCase family
BWEI_RS05140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BWEI_RS05150	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BWEI_RS05155	COG0543	2 iron, 2 sulfur cluster binding
BWEI_RS05160	COG0167	dihydroorotate dehydrogenase activity
BWEI_RS05165	COG0284	orotidine-5'-phosphate decarboxylase activity
BWEI_RS05170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BWEI_RS05180	COG3069	C4-dicarboxylate transmembrane transporter activity
BWEI_RS05200	COG0006	proline dipeptidase activity
BWEI_RS05215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BWEI_RS05220	COG1561	YicC-like family, N-terminal region
BWEI_RS05235	COG1758	RNA polymerase activity
BWEI_RS05240	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWEI_RS05245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BWEI_RS05250	COG0242	peptide deformylase activity
BWEI_RS05255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BWEI_RS05260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BWEI_RS05260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BWEI_RS05265	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BWEI_RS05270	COG0631	protein serine/threonine phosphatase activity
BWEI_RS05275	COG2815	serine threonine protein kinase
BWEI_RS05275	COG0515	serine threonine protein kinase
BWEI_RS05285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BWEI_RS05290	COG1564	THIamine pyrophosphokinase
BWEI_RS05305	COG1302	Protein conserved in bacteria
BWEI_RS05310	COG1461	Dihydroxyacetone kinase
BWEI_RS05315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BWEI_RS05320	COG2050	protein possibly involved in aromatic compounds catabolism
BWEI_RS05320	COG1349	DNA-binding transcription factor activity
BWEI_RS05325	COG0416	fatty acid biosynthetic process
BWEI_RS05330	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BWEI_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS05340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWEI_RS05345	COG0571	ribonuclease III activity
BWEI_RS05350	COG1196	nuclear chromosome segregation
BWEI_RS05355	COG0552	protein localization to endoplasmic reticulum
BWEI_RS05360	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BWEI_RS05365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BWEI_RS05375	COG1837	Belongs to the UPF0109 family
BWEI_RS05380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BWEI_RS05385	COG0336	Belongs to the RNA methyltransferase TrmD family
BWEI_RS05390	COG0335	large ribosomal subunit rRNA binding
BWEI_RS05405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BWEI_RS05410	COG0045	succinate-CoA ligase (ADP-forming) activity
BWEI_RS05415	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BWEI_RS05420	COG0758	DNA mediated transformation
BWEI_RS05425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWEI_RS05430	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BWEI_RS05435	COG4974	Belongs to the 'phage' integrase family
BWEI_RS05440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BWEI_RS05445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BWEI_RS05450	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BWEI_RS05455	COG0052	Belongs to the universal ribosomal protein uS2 family
BWEI_RS05460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BWEI_RS05465	COG0528	UMP kinase activity
BWEI_RS05470	COG0233	cytoplasmic translational termination
BWEI_RS05480	COG4589	Belongs to the CDS family
BWEI_RS05490	COG0750	zinc metalloprotease
BWEI_RS05495	COG0442	prolyl-tRNA aminoacylation
BWEI_RS05505	COG0779	Required for maturation of 30S ribosomal subunits
BWEI_RS05510	COG0195	Participates in both transcription termination and antitermination
BWEI_RS05515	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BWEI_RS05520	COG1358	cellular component organization or biogenesis
BWEI_RS05525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BWEI_RS05530	COG1550	Protein conserved in bacteria
BWEI_RS05535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BWEI_RS05545	COG0196	riboflavin kinase activity
BWEI_RS05555	COG1185	polyribonucleotide nucleotidyltransferase activity
BWEI_RS05560	COG0726	polysaccharide deacetylase
BWEI_RS05565	COG0612	Peptidase, M16
BWEI_RS05570	COG1873	PFAM PRC-barrel domain
BWEI_RS05575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWEI_RS05580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BWEI_RS05585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWEI_RS05590	COG0527	aspartate kinase activity
BWEI_RS05600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BWEI_RS05605	COG0740	serine-type endopeptidase activity
BWEI_RS05615	COG1674	ftsk spoiiie
BWEI_RS05620	COG2188	Transcriptional regulator
BWEI_RS05625	COG1744	ABC transporter substrate-binding protein PnrA-like
BWEI_RS05630	COG3845	ABC transporter
BWEI_RS05635	COG4603	Belongs to the binding-protein-dependent transport system permease family
BWEI_RS05640	COG1079	Belongs to the binding-protein-dependent transport system permease family
BWEI_RS05645	COG0612	Peptidase, M16
BWEI_RS05650	COG0612	Peptidase, M16
BWEI_RS05655	COG0300	oxidoreductase activity
BWEI_RS05670	COG1426	Protein conserved in bacteria
BWEI_RS05675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BWEI_RS05680	COG1058	Belongs to the CinA family
BWEI_RS05680	COG1546	Belongs to the CinA family
BWEI_RS05685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BWEI_RS05690	COG1418	mRNA catabolic process
BWEI_RS05695	COG1692	metallophosphoesterase
BWEI_RS05700	COG2359	stage V sporulation protein S
BWEI_RS05710	COG0674	pyruvate-flavodoxin oxidoreductase activity
BWEI_RS05710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BWEI_RS05715	COG1013	pyruvate-flavodoxin oxidoreductase activity
BWEI_RS05720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BWEI_RS05725	COG4550	Control of competence regulator ComK, YlbF/YmcA
BWEI_RS05735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BWEI_RS05740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BWEI_RS05745	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BWEI_RS05755	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BWEI_RS05760	COG1368	sulfuric ester hydrolase activity
BWEI_RS05770	COG3773	Cell wall hydrolase
BWEI_RS05780	COG2723	6-phospho-beta-galactosidase activity
BWEI_RS05785	COG2188	Transcriptional regulator
BWEI_RS05795	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWEI_RS05800	COG0596	Alpha beta hydrolase
BWEI_RS05800	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWEI_RS05805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS05815	COG1346	cytolysis
BWEI_RS05855	COG5001	Diguanylate cyclase
BWEI_RS05855	COG3300	MHYT domain
BWEI_RS05860	COG0346	lactoylglutathione lyase activity
BWEI_RS05875	COG2364	Membrane
BWEI_RS05880	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWEI_RS05885	COG2706	6-phosphogluconolactonase activity
BWEI_RS05890	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BWEI_RS05895	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWEI_RS05900	COG2169	Transcriptional regulator
BWEI_RS05905	COG0708	Exodeoxyribonuclease III
BWEI_RS05910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS05915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS05920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS05925	COG1120	ATPase activity
BWEI_RS05930	COG2819	hydrolase of the alpha beta superfamily
BWEI_RS05950	COG1937	Protein conserved in bacteria
BWEI_RS05955	COG2608	mercury ion transmembrane transporter activity
BWEI_RS05960	COG2217	Heavy metal translocating P-type atpase
BWEI_RS05975	COG2116	formate transmembrane transporter activity
BWEI_RS05980	COG1408	metallophosphoesterase
BWEI_RS05985	COG1473	amidohydrolase
BWEI_RS05995	COG1113	amino acid transport
BWEI_RS06005	COG2322	membrane
BWEI_RS06010	COG1979	alcohol dehydrogenase
BWEI_RS06015	COG1349	DNA-binding transcription factor activity
BWEI_RS06020	COG1105	Belongs to the carbohydrate kinase PfkB family
BWEI_RS06025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWEI_RS06025	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWEI_RS06025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BWEI_RS06030	COG1388	LysM domain
BWEI_RS06030	COG3584	3D domain protein
BWEI_RS06040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BWEI_RS06060	COG0464	growth
BWEI_RS06065	COG2860	membrane
BWEI_RS06070	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWEI_RS06075	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BWEI_RS06080	COG0789	Transcriptional regulator
BWEI_RS06085	COG0174	glutamine synthetase
BWEI_RS06090	COG1695	Transcriptional regulator
BWEI_RS06105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BWEI_RS06110	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWEI_RS06120	COG0737	Belongs to the 5'-nucleotidase family
BWEI_RS06125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS06135	COG3639	organic phosphonate transmembrane transporter activity
BWEI_RS06155	COG3763	UPF0154 protein
BWEI_RS06160	COG1132	(ABC) transporter
BWEI_RS06165	COG1132	(ABC) transporter
BWEI_RS06185	COG5632	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS06185	COG3409	Peptidoglycan-binding domain 1 protein
BWEI_RS06195	COG0730	response to heat
BWEI_RS06210	COG1346	cytolysis
BWEI_RS06220	COG0583	DNA-binding transcription factor activity
BWEI_RS06230	COG1131	(ABC) transporter
BWEI_RS06235	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BWEI_RS06240	COG1473	amidohydrolase
BWEI_RS06250	COG0785	Cytochrome C biogenesis protein
BWEI_RS06255	COG4846	Membrane protein involved in cytochrome C biogenesis
BWEI_RS06280	COG2226	methyltransferase
BWEI_RS06290	COG2986	histidine ammonia-lyase
BWEI_RS06295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BWEI_RS06305	COG0010	Belongs to the arginase family
BWEI_RS06310	COG1329	Transcriptional regulator
BWEI_RS06320	COG1902	pentaerythritol trinitrate reductase activity
BWEI_RS06325	COG0069	glutamate synthase activity
BWEI_RS06330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWEI_RS06335	COG0346	lactoylglutathione lyase activity
BWEI_RS06340	COG0400	carboxylic ester hydrolase activity
BWEI_RS06350	COG5002	protein histidine kinase activity
BWEI_RS06360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS06400	COG1396	sequence-specific DNA binding
BWEI_RS06405	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS06410	COG1268	BioY protein
BWEI_RS06415	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS06420	COG0183	Belongs to the thiolase family
BWEI_RS06435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BWEI_RS06445	COG2211	Major facilitator Superfamily
BWEI_RS06475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BWEI_RS06480	COG1132	(ABC) transporter
BWEI_RS06495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS06515	COG0824	Thioesterase
BWEI_RS06520	COG4841	protein insertion into membrane
BWEI_RS06530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BWEI_RS06530	COG1328	CTP reductase activity
BWEI_RS06540	COG0745	RESPONSE REGULATOR receiver
BWEI_RS06545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWEI_RS06550	COG1832	CoA-binding protein
BWEI_RS06555	COG0187	DNA topoisomerase II activity
BWEI_RS06560	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWEI_RS06565	COG0673	inositol 2-dehydrogenase activity
BWEI_RS06585	COG1131	(ABC) transporter
BWEI_RS06600	COG1316	TRANSCRIPTIONal
BWEI_RS06605	COG4166	transmembrane transport
BWEI_RS06610	COG4166	transmembrane transport
BWEI_RS06615	COG4166	transmembrane transport
BWEI_RS06620	COG2226	methyltransferase
BWEI_RS06650	COG3326	Membrane
BWEI_RS06655	COG2962	Rard protein
BWEI_RS06660	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BWEI_RS06665	COG1657	PFAM Prenyltransferase squalene oxidase
BWEI_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS06680	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS06690	COG4145	pantothenate transmembrane transporter activity
BWEI_RS06705	COG0165	Argininosuccinate lyase
BWEI_RS06715	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS06735	COG0494	nUDIX hydrolase
BWEI_RS06745	COG0716	FMN binding
BWEI_RS06755	COG1278	Cold shock
BWEI_RS06780	COG2720	vancomycin resistance protein
BWEI_RS06785	COG0765	amino acid transport
BWEI_RS06790	COG1126	abc transporter atp-binding protein
BWEI_RS06795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS06800	COG2514	catechol 2,3-dioxygenase activity
BWEI_RS06810	COG1285	pathogenesis
BWEI_RS06840	COG0825	malonyl-CoA metabolic process
BWEI_RS06855	COG0277	FAD linked oxidase domain protein
BWEI_RS06865	COG2808	Putative FMN-binding domain
BWEI_RS06885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BWEI_RS06890	COG0604	alcohol dehydrogenase
BWEI_RS06895	COG0640	Transcriptional regulator
BWEI_RS06950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS06965	COG3781	membrane
BWEI_RS06990	COG1164	Oligoendopeptidase f
BWEI_RS06995	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BWEI_RS07015	COG1193	negative regulation of DNA recombination
BWEI_RS07035	COG0583	DNA-binding transcription factor activity
BWEI_RS07055	COG3739	integral membrane protein
BWEI_RS07075	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BWEI_RS07080	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWEI_RS07095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWEI_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS07105	COG0534	Mate efflux family protein
BWEI_RS07115	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS07120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWEI_RS07130	COG2814	Major facilitator Superfamily
BWEI_RS07140	COG1113	amino acid transport
BWEI_RS07145	COG0604	alcohol dehydrogenase
BWEI_RS07185	COG2072	flavoprotein involved in K transport
BWEI_RS07195	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS07215	COG1151	hydroxylamine reductase activity
BWEI_RS07240	COG0814	amino acid
BWEI_RS07280	COG5002	protein histidine kinase activity
BWEI_RS07325	COG0741	lytic transglycosylase activity
BWEI_RS07345	COG1876	peptidase activity
BWEI_RS07375	COG1191	sigma factor activity
BWEI_RS07390	COG1733	regulation of RNA biosynthetic process
BWEI_RS07395	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWEI_RS07400	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS07410	COG0384	phenazine biosynthesis protein PhzF
BWEI_RS07425	COG0494	nUDIX hydrolase
BWEI_RS07440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS07450	COG4702	Belongs to the UPF0303 family
BWEI_RS07455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BWEI_RS07460	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BWEI_RS07470	COG1070	Carbohydrate kinase
BWEI_RS07475	COG2706	6-phosphogluconolactonase activity
BWEI_RS07480	COG3813	Protein conserved in bacteria
BWEI_RS07485	COG1357	PFAM Pentapeptide repeats (8 copies)
BWEI_RS07495	COG0697	spore germination
BWEI_RS07520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BWEI_RS07530	COG0789	Transcriptional regulator
BWEI_RS07535	COG1253	flavin adenine dinucleotide binding
BWEI_RS07545	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BWEI_RS07565	COG0477	Major facilitator Superfamily
BWEI_RS07575	COG0500	methyltransferase
BWEI_RS07585	COG2261	transglycosylase associated protein
BWEI_RS07590	COG0628	permease
BWEI_RS07605	COG0110	maltose O-acetyltransferase activity
BWEI_RS07610	COG0738	Major facilitator superfamily
BWEI_RS07615	COG1940	carbohydrate kinase activity
BWEI_RS07620	COG0346	lactoylglutathione lyase activity
BWEI_RS07645	COG2365	Tyrosine phosphatase family
BWEI_RS07650	COG1011	Hydrolase
BWEI_RS07680	COG1131	(ABC) transporter
BWEI_RS07700	COG1733	regulation of RNA biosynthetic process
BWEI_RS07705	COG0778	Nitroreductase
BWEI_RS07710	COG1785	Belongs to the alkaline phosphatase family
BWEI_RS07740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BWEI_RS07750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWEI_RS07755	COG2356	endonuclease I
BWEI_RS07760	COG1288	antiporter activity
BWEI_RS07765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BWEI_RS07785	COG1122	ATPase activity
BWEI_RS07825	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWEI_RS07835	COG2031	fatty acid transporter
BWEI_RS07840	COG2890	protein-(glutamine-N5) methyltransferase activity
BWEI_RS07855	COG0833	amino acid
BWEI_RS07860	COG1414	Transcriptional regulator
BWEI_RS07865	COG4187	Peptidase family M20/M25/M40
BWEI_RS07915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS07925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS07950	COG2234	aminopeptidase activity
BWEI_RS08250	COG1609	Transcriptional regulator
BWEI_RS08255	COG2814	Major facilitator Superfamily
BWEI_RS08260	COG0673	inositol 2-dehydrogenase activity
BWEI_RS08285	COG0191	fructose-bisphosphate aldolase activity
BWEI_RS08290	COG3718	enzyme involved in inositol metabolism
BWEI_RS08325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BWEI_RS08330	COG1288	antiporter activity
BWEI_RS08345	COG1476	TRANSCRIPTIONal
BWEI_RS08365	COG0789	Transcriptional regulator
BWEI_RS08450	COG2814	Major facilitator Superfamily
BWEI_RS08455	COG1846	Transcriptional regulator
BWEI_RS08470	COG0477	Major facilitator Superfamily
BWEI_RS08480	COG2843	Capsule synthesis protein
BWEI_RS08485	COG1876	peptidase activity
BWEI_RS08525	COG2814	Major facilitator Superfamily
BWEI_RS08565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BWEI_RS08585	COG1619	proteins homologs of microcin C7 resistance protein MccF
BWEI_RS08600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS08615	COG5002	protein histidine kinase activity
BWEI_RS08615	COG3850	Histidine kinase
BWEI_RS08640	COG0577	efflux transmembrane transporter activity
BWEI_RS08660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BWEI_RS08680	COG1690	Belongs to the RtcB family
BWEI_RS08715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BWEI_RS08745	COG5002	protein histidine kinase activity
BWEI_RS08745	COG3850	Histidine kinase
BWEI_RS08750	COG0745	RESPONSE REGULATOR receiver
BWEI_RS08780	COG2814	Major facilitator Superfamily
BWEI_RS08790	COG2226	methyltransferase
BWEI_RS08810	COG0346	lactoylglutathione lyase activity
BWEI_RS08825	COG1522	sequence-specific DNA binding
BWEI_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS08835	COG1309	transcriptional regulator
BWEI_RS08840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWEI_RS08840	COG3320	Male sterility
BWEI_RS08850	COG0640	Transcriptional regulator
BWEI_RS08855	COG0346	lactoylglutathione lyase activity
BWEI_RS08860	COG0798	PFAM Bile acid sodium symporter
BWEI_RS08875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BWEI_RS08880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWEI_RS08885	COG1999	signal sequence binding
BWEI_RS08900	COG1121	(ABC) transporter
BWEI_RS08905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BWEI_RS08910	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWEI_RS08930	COG1575	Belongs to the MenA family. Type 1 subfamily
BWEI_RS08940	COG0745	RESPONSE REGULATOR receiver
BWEI_RS08945	COG5002	protein histidine kinase activity
BWEI_RS08970	COG1073	alpha beta
BWEI_RS08985	COG1131	(ABC) transporter
BWEI_RS09010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BWEI_RS09025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS09035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BWEI_RS09045	COG0574	Belongs to the PEP-utilizing enzyme family
BWEI_RS09045	COG3848	Pyruvate phosphate dikinase
BWEI_RS09060	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BWEI_RS09075	COG3314	Sporulation integral membrane protein YlbJ
BWEI_RS09085	COG0640	Transcriptional regulator
BWEI_RS09110	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS09140	COG1414	Transcriptional regulator
BWEI_RS09145	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BWEI_RS09150	COG1984	allophanate hydrolase subunit 2
BWEI_RS09155	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BWEI_RS09170	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BWEI_RS09175	COG3104	oligopeptide transport
BWEI_RS09185	COG0768	penicillin binding
BWEI_RS09215	COG4335	DNA alkylation repair
BWEI_RS09225	COG0833	amino acid
BWEI_RS09235	COG0730	response to heat
BWEI_RS09260	COG0456	acetyltransferase
BWEI_RS09260	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWEI_RS09270	COG0596	Alpha beta hydrolase
BWEI_RS09275	COG0745	RESPONSE REGULATOR receiver
BWEI_RS09280	COG0642	Histidine kinase
BWEI_RS09285	COG5002	protein histidine kinase activity
BWEI_RS09295	COG0745	RESPONSE REGULATOR receiver
BWEI_RS09330	COG4977	sequence-specific DNA binding
BWEI_RS09375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS09380	COG0697	spore germination
BWEI_RS09395	COG0456	acetyltransferase
BWEI_RS09400	COG2207	Transcriptional regulator
BWEI_RS09430	COG1725	Transcriptional regulator
BWEI_RS09465	COG1846	Transcriptional regulator
BWEI_RS09470	COG0778	Nitroreductase
BWEI_RS09480	COG0714	Associated with various cellular activities
BWEI_RS09505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BWEI_RS09520	COG0753	catalase activity
BWEI_RS09525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BWEI_RS09545	COG0714	Associated with various cellular activities
BWEI_RS09565	COG0346	lactoylglutathione lyase activity
BWEI_RS09570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS09610	COG3655	Transcriptional regulator
BWEI_RS09620	COG3239	Fatty acid desaturase
BWEI_RS09625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWEI_RS09630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BWEI_RS09635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BWEI_RS09645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS09650	COG2207	Transcriptional regulator
BWEI_RS09655	COG1472	Belongs to the glycosyl hydrolase 3 family
BWEI_RS09675	COG2329	Antibiotic biosynthesis monooxygenase
BWEI_RS09680	COG0346	lactoylglutathione lyase activity
BWEI_RS09695	COG2226	methyltransferase
BWEI_RS09715	COG2390	Transcriptional regulator
BWEI_RS09720	COG1129	ABC transporter
BWEI_RS09735	COG1879	ABC-type sugar transport system periplasmic component
BWEI_RS09740	COG0579	oxidoreductase
BWEI_RS09750	COG3829	transcription factor binding
BWEI_RS09750	COG3290	protein histidine kinase activity
BWEI_RS09760	COG1024	Enoyl-CoA hydratase
BWEI_RS09765	COG2610	gluconate transmembrane transporter activity
BWEI_RS09775	COG0431	NADPH-dependent FMN reductase
BWEI_RS09785	COG0346	lactoylglutathione lyase activity
BWEI_RS09795	COG1388	LysM domain
BWEI_RS09795	COG3584	3D domain protein
BWEI_RS09835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BWEI_RS09835	COG1605	Chorismate mutase
BWEI_RS09850	COG0287	Prephenate dehydrogenase
BWEI_RS09875	COG1309	transcriptional regulator
BWEI_RS09880	COG1033	growth of symbiont in host cell
BWEI_RS09880	COG2409	Drug exporters of the RND superfamily
BWEI_RS09915	COG0488	(ABC) transporter
BWEI_RS09930	COG1368	sulfuric ester hydrolase activity
BWEI_RS09935	COG2814	Major facilitator Superfamily
BWEI_RS09980	COG0697	spore germination
BWEI_RS09995	COG2746	aminoglycoside 3-N-acetyltransferase activity
BWEI_RS10025	COG0628	permease
BWEI_RS10065	COG2188	Transcriptional regulator
BWEI_RS10070	COG1131	(ABC) transporter
BWEI_RS10090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BWEI_RS10095	COG0436	Aminotransferase
BWEI_RS10130	COG2226	methyltransferase
BWEI_RS10145	COG2261	transglycosylase associated protein
BWEI_RS10165	COG0477	Major facilitator Superfamily
BWEI_RS10165	COG2814	Major facilitator Superfamily
BWEI_RS10170	COG4533	DNA binding
BWEI_RS10175	COG0789	Transcriptional regulator
BWEI_RS10190	COG2814	Major facilitator Superfamily
BWEI_RS10205	COG1335	isochorismatase
BWEI_RS10230	COG1307	EDD domain protein, DegV family
BWEI_RS10245	COG1164	Oligoendopeptidase f
BWEI_RS10250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWEI_RS10275	COG0745	RESPONSE REGULATOR receiver
BWEI_RS10285	COG2936	dipeptidyl-peptidase activity
BWEI_RS10325	COG0667	Aldo Keto reductase
BWEI_RS10345	COG4948	Mandelate Racemase Muconate Lactonizing
BWEI_RS10355	COG4166	transmembrane transport
BWEI_RS10360	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BWEI_RS10375	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS10415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWEI_RS10420	COG3938	Belongs to the proline racemase family
BWEI_RS10430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BWEI_RS10435	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS10440	COG1115	amino acid carrier protein
BWEI_RS10445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWEI_RS10450	COG1162	GTPase activity
BWEI_RS10465	COG2318	DinB family
BWEI_RS10470	COG3397	chitin binding
BWEI_RS10475	COG1227	inorganic diphosphatase activity
BWEI_RS10495	COG4637	Psort location Cytoplasmic, score
BWEI_RS10515	COG0514	ATP-dependent DNA helicase (RecQ)
BWEI_RS10520	COG2105	PFAM AIG2 family protein
BWEI_RS10530	COG3973	AAA domain
BWEI_RS10570	COG2315	Protein conserved in bacteria
BWEI_RS10575	COG2205	protein histidine kinase activity
BWEI_RS10590	COG1819	glycosyl
BWEI_RS10600	COG3397	chitin binding
BWEI_RS10620	COG2153	protein acetylation
BWEI_RS10650	COG4175	Glycine betaine
BWEI_RS10650	COG0517	IMP dehydrogenase activity
BWEI_RS10655	COG4176	ABC-type proline glycine betaine transport system permease component
BWEI_RS10690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWEI_RS10690	COG0456	acetyltransferase
BWEI_RS10695	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS10705	COG2223	nitrite transmembrane transporter activity
BWEI_RS10725	COG1959	2 iron, 2 sulfur cluster binding
BWEI_RS10745	COG1349	DNA-binding transcription factor activity
BWEI_RS10775	COG1309	transcriptional regulator
BWEI_RS10780	COG3844	kynureninase activity
BWEI_RS10785	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BWEI_RS10790	COG3483	tryptophan 2,3-dioxygenase activity
BWEI_RS10815	COG2959	enzyme of heme biosynthesis
BWEI_RS10830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS10865	COG3773	Cell wall hydrolase
BWEI_RS10875	COG0745	RESPONSE REGULATOR receiver
BWEI_RS10880	COG2205	protein histidine kinase activity
BWEI_RS10890	COG0583	DNA-binding transcription factor activity
BWEI_RS10895	COG0667	Aldo Keto reductase
BWEI_RS10900	COG0488	(ABC) transporter
BWEI_RS10915	COG1136	(ABC) transporter
BWEI_RS10920	COG0577	efflux transmembrane transporter activity
BWEI_RS10940	COG0460	homoserine dehydrogenase
BWEI_RS10945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS10955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BWEI_RS11005	COG2124	cytochrome p450
BWEI_RS11045	COG0561	phosphatase activity
BWEI_RS11050	COG5002	protein histidine kinase activity
BWEI_RS11055	COG0768	penicillin binding
BWEI_RS11065	COG1819	glycosyl
BWEI_RS11070	COG1794	racemase activity, acting on amino acids and derivatives
BWEI_RS11075	COG4720	Psort location CytoplasmicMembrane, score
BWEI_RS11080	COG1122	ATPase activity
BWEI_RS11090	COG2205	protein histidine kinase activity
BWEI_RS11100	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BWEI_RS11110	COG0745	RESPONSE REGULATOR receiver
BWEI_RS11115	COG5002	protein histidine kinase activity
BWEI_RS11120	COG0604	alcohol dehydrogenase
BWEI_RS11125	COG0671	phosphoesterase, PA-phosphatase related
BWEI_RS11130	COG0768	penicillin binding
BWEI_RS11165	COG2814	Major facilitator Superfamily
BWEI_RS11175	COG1733	regulation of RNA biosynthetic process
BWEI_RS11190	COG0584	glycerophosphoryl diester phosphodiesterase
BWEI_RS11210	COG0697	spore germination
BWEI_RS11230	COG0494	nUDIX hydrolase
BWEI_RS11240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS11250	COG2223	nitrite transmembrane transporter activity
BWEI_RS11255	COG0592	DNA-directed DNA polymerase activity
BWEI_RS11260	COG1051	belongs to the nudix hydrolase family
BWEI_RS11285	COG3878	Protein conserved in bacteria
BWEI_RS11310	COG4667	esterase of the alpha-beta hydrolase superfamily
BWEI_RS11325	COG2318	DinB family
BWEI_RS11350	COG0322	excinuclease ABC activity
BWEI_RS11370	COG3961	Belongs to the TPP enzyme family
BWEI_RS11375	COG1132	(ABC) transporter
BWEI_RS11385	COG1183	phosphatidylcholine synthase activity
BWEI_RS11390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWEI_RS11415	COG1011	Hydrolase
BWEI_RS11420	COG0745	RESPONSE REGULATOR receiver
BWEI_RS11425	COG5002	protein histidine kinase activity
BWEI_RS11445	COG1136	(ABC) transporter
BWEI_RS11450	COG0577	efflux transmembrane transporter activity
BWEI_RS11460	COG1073	alpha beta
BWEI_RS11465	COG0657	acetylesterase activity
BWEI_RS11470	COG0076	glutamate decarboxylase activity
BWEI_RS11485	COG1523	belongs to the glycosyl hydrolase 13 family
BWEI_RS11490	COG3227	Zinc metalloprotease (Elastase)
BWEI_RS11495	COG0737	Belongs to the 5'-nucleotidase family
BWEI_RS11505	COG0201	protein transport
BWEI_RS11510	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWEI_RS11515	COG0697	spore germination
BWEI_RS11520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS11535	COG2323	membrane
BWEI_RS11570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS11610	COG1733	regulation of RNA biosynthetic process
BWEI_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS11640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BWEI_RS11665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BWEI_RS11685	COG1686	Belongs to the peptidase S11 family
BWEI_RS11690	COG2318	DinB family
BWEI_RS11735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BWEI_RS11740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BWEI_RS11745	COG1024	Enoyl-CoA hydratase
BWEI_RS11750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWEI_RS11755	COG0511	ligase activity, forming carbon-carbon bonds
BWEI_RS11760	COG0439	Biotin carboxylase
BWEI_RS11765	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS11775	COG1309	transcriptional regulator
BWEI_RS11785	COG1131	(ABC) transporter
BWEI_RS11795	COG1408	metallophosphoesterase
BWEI_RS11805	COG0823	Involved in the tonB-independent uptake of proteins
BWEI_RS11810	COG3397	chitin binding
BWEI_RS11840	COG0697	spore germination
BWEI_RS11855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS11855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS11860	COG1252	NADH dehydrogenase
BWEI_RS11870	COG1404	Belongs to the peptidase S8 family
BWEI_RS11905	COG0768	penicillin binding
BWEI_RS11910	COG0768	penicillin binding
BWEI_RS11920	COG1595	DNA-templated transcription, initiation
BWEI_RS11930	COG0577	efflux transmembrane transporter activity
BWEI_RS11935	COG1136	(ABC) transporter
BWEI_RS11940	COG2205	protein histidine kinase activity
BWEI_RS11945	COG0745	RESPONSE REGULATOR receiver
BWEI_RS11950	COG0768	penicillin binding
BWEI_RS11975	COG1686	Belongs to the peptidase S11 family
BWEI_RS11980	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS12005	COG1136	(ABC) transporter
BWEI_RS12010	COG0110	maltose O-acetyltransferase activity
BWEI_RS12025	COG2195	Cleaves the N-terminal amino acid of tripeptides
BWEI_RS12050	COG0588	phosphoglycerate mutase activity
BWEI_RS12060	COG0693	protein deglycase activity
BWEI_RS12075	COG0577	efflux transmembrane transporter activity
BWEI_RS12075	COG1136	(ABC) transporter
BWEI_RS12090	COG1309	transcriptional regulator
BWEI_RS12130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BWEI_RS12140	COG2971	BadF BadG BcrA BcrD
BWEI_RS12145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BWEI_RS12165	COG1649	PFAM Uncharacterised BCR, COG1649
BWEI_RS12190	COG1595	DNA-templated transcription, initiation
BWEI_RS12195	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BWEI_RS12205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BWEI_RS12230	COG1396	sequence-specific DNA binding
BWEI_RS12250	COG0189	ligase activity
BWEI_RS12265	COG1132	(ABC) transporter
BWEI_RS12270	COG1132	(ABC) transporter
BWEI_RS12285	COG2258	MOSC domain
BWEI_RS12290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWEI_RS12295	COG0583	DNA-binding transcription factor activity
BWEI_RS12310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BWEI_RS12315	COG0583	DNA-binding transcription factor activity
BWEI_RS12345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS12355	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BWEI_RS12360	COG0596	Alpha beta hydrolase
BWEI_RS12385	COG1247	-acetyltransferase
BWEI_RS12400	COG0531	amino acid
BWEI_RS12405	COG0697	spore germination
BWEI_RS12415	COG1309	transcriptional regulator
BWEI_RS12420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS12430	COG1846	Transcriptional regulator
BWEI_RS12450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWEI_RS12480	COG1253	flavin adenine dinucleotide binding
BWEI_RS12490	COG0028	Belongs to the TPP enzyme family
BWEI_RS12505	COG0596	Alpha beta hydrolase
BWEI_RS12515	COG1136	(ABC) transporter
BWEI_RS12525	COG3655	Transcriptional regulator
BWEI_RS12530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BWEI_RS12535	COG1187	pseudouridine synthase activity
BWEI_RS12545	COG2329	Antibiotic biosynthesis monooxygenase
BWEI_RS12560	COG1115	amino acid carrier protein
BWEI_RS12565	COG2318	DinB family
BWEI_RS12575	COG0776	regulation of translation
BWEI_RS12590	COG2814	Major facilitator Superfamily
BWEI_RS12595	COG3251	PFAM MbtH domain protein
BWEI_RS12600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BWEI_RS12605	COG3433	isochorismatase activity
BWEI_RS12605	COG1535	isochorismatase
BWEI_RS12610	COG1021	2,3-dihydroxybenzoate-AMP ligase
BWEI_RS12615	COG1169	isochorismate synthase
BWEI_RS12620	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS12625	COG2223	nitrite transmembrane transporter activity
BWEI_RS12645	COG0419	ATPase involved in DNA repair
BWEI_RS12650	COG0420	3'-5' exonuclease activity
BWEI_RS12665	COG1024	Enoyl-CoA hydratase
BWEI_RS12670	COG1280	lysine exporter protein (LysE YggA)
BWEI_RS12675	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS12680	COG2084	Dehydrogenase
BWEI_RS12685	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS12690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BWEI_RS12695	COG2079	MmgE PrpD family protein
BWEI_RS12700	COG0372	Belongs to the citrate synthase family
BWEI_RS12705	COG2814	Major facilitator Superfamily
BWEI_RS12715	COG4499	WXG100 protein secretion system (Wss), protein YukC
BWEI_RS12715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWEI_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS12760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWEI_RS12830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS12835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BWEI_RS12840	COG0671	phosphoesterase, PA-phosphatase related
BWEI_RS12850	COG4991	sh3 domain protein
BWEI_RS12850	COG3064	Membrane
BWEI_RS12850	COG0515	serine threonine protein kinase
BWEI_RS12925	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BWEI_RS12930	COG4479	Belongs to the UPF0346 family
BWEI_RS12940	COG1509	lysine 2,3-aminomutase activity
BWEI_RS12945	COG3829	transcription factor binding
BWEI_RS12950	COG0456	acetyltransferase
BWEI_RS12955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWEI_RS12960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BWEI_RS12965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BWEI_RS12970	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWEI_RS12985	COG5506	Protein of unknown function (DUF1694)
BWEI_RS12990	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS12995	COG1253	flavin adenine dinucleotide binding
BWEI_RS13040	COG1174	glycine betaine transport
BWEI_RS13045	COG0517	IMP dehydrogenase activity
BWEI_RS13045	COG1125	glycine betaine transport
BWEI_RS13065	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BWEI_RS13075	COG1070	Carbohydrate kinase
BWEI_RS13095	COG1064	alcohol dehydrogenase
BWEI_RS13100	COG1737	Transcriptional regulator
BWEI_RS13105	COG2197	response regulator
BWEI_RS13110	COG4585	Histidine kinase
BWEI_RS13110	COG2203	Gaf domain
BWEI_RS13125	COG1335	isochorismatase
BWEI_RS13140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWEI_RS13145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS13150	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS13160	COG0367	asparagine synthase
BWEI_RS13165	COG0071	Belongs to the small heat shock protein (HSP20) family
BWEI_RS13170	COG1999	signal sequence binding
BWEI_RS13175	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BWEI_RS13180	COG1307	EDD domain protein, DegV family
BWEI_RS13190	COG0805	protein transport
BWEI_RS13200	COG1272	protein, Hemolysin III
BWEI_RS13215	COG0768	penicillin binding
BWEI_RS13255	COG0546	phosphoglycolate phosphatase activity
BWEI_RS13265	COG4473	ABC transporter
BWEI_RS13270	COG1131	(ABC) transporter
BWEI_RS13275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BWEI_RS13280	COG0456	acetyltransferase
BWEI_RS13290	COG1794	racemase activity, acting on amino acids and derivatives
BWEI_RS13300	COG2610	gluconate transmembrane transporter activity
BWEI_RS13325	COG0733	neurotransmitter:sodium symporter activity
BWEI_RS13375	COG1674	ftsk spoiiie
BWEI_RS13395	COG0017	Asparaginyl-tRNA synthetase
BWEI_RS13400	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWEI_RS13445	COG0018	arginyl-trna synthetase
BWEI_RS13450	COG2521	methyltransferase
BWEI_RS13450	COG2136	Putative SAM-dependent methyltransferase
BWEI_RS13465	COG1413	lyase activity
BWEI_RS13485	COG0488	(ABC) transporter
BWEI_RS13490	COG1418	mRNA catabolic process
BWEI_RS13515	COG0582	viral genome integration into host DNA
BWEI_RS13570	COG2359	stage V sporulation protein S
BWEI_RS13600	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BWEI_RS13605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWEI_RS13610	COG2146	nitrite reductase [NAD(P)H] activity
BWEI_RS13615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BWEI_RS13615	COG1587	Uroporphyrinogen-III synthase
BWEI_RS13625	COG1648	precorrin-2 dehydrogenase activity
BWEI_RS13650	COG2223	nitrite transmembrane transporter activity
BWEI_RS13660	COG0314	molybdopterin synthase activity
BWEI_RS13665	COG0303	'Molybdopterin
BWEI_RS13670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWEI_RS13675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BWEI_RS13680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWEI_RS13685	COG2181	nitrate reductase activity
BWEI_RS13690	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BWEI_RS13695	COG1140	nitrate reductase beta subunit
BWEI_RS13700	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BWEI_RS13715	COG0714	Associated with various cellular activities
BWEI_RS13720	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BWEI_RS13725	COG1305	Transglutaminase-like
BWEI_RS13730	COG0386	Belongs to the glutathione peroxidase family
BWEI_RS13740	COG0426	domain, Protein
BWEI_RS13740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BWEI_RS13760	COG1595	DNA-templated transcription, initiation
BWEI_RS13765	COG0604	alcohol dehydrogenase
BWEI_RS13775	COG0346	lactoylglutathione lyase activity
BWEI_RS13780	COG1082	Xylose isomerase domain protein TIM barrel
BWEI_RS13800	COG2226	methyltransferase
BWEI_RS13825	COG3874	Sporulation protein YtfJ
BWEI_RS13845	COG0456	acetyltransferase
BWEI_RS13870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS13875	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS13880	COG1819	glycosyl
BWEI_RS13895	COG4106	trans-aconitate 2-methyltransferase activity
BWEI_RS13900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BWEI_RS13910	COG0561	phosphatase activity
BWEI_RS13920	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS13935	COG2211	Major facilitator Superfamily
BWEI_RS13945	COG0494	nUDIX hydrolase
BWEI_RS13950	COG1876	peptidase activity
BWEI_RS13960	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS13975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWEI_RS13980	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS13995	COG1253	flavin adenine dinucleotide binding
BWEI_RS14000	COG2839	Protein conserved in bacteria
BWEI_RS14005	COG0702	epimerase
BWEI_RS14020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWEI_RS14025	COG1607	acyl-coa hydrolase
BWEI_RS14030	COG3689	TIGRFAM TIGR03943 family protein
BWEI_RS14035	COG0701	Predicted permease
BWEI_RS14045	COG2244	polysaccharide biosynthetic process
BWEI_RS14050	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS14055	COG1051	belongs to the nudix hydrolase family
BWEI_RS14060	COG5337	Spore coat protein CotH
BWEI_RS14070	COG0406	alpha-ribazole phosphatase activity
BWEI_RS14080	COG0346	lactoylglutathione lyase activity
BWEI_RS14085	COG4166	transmembrane transport
BWEI_RS14095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BWEI_RS14100	COG1902	pentaerythritol trinitrate reductase activity
BWEI_RS14115	COG0803	Belongs to the bacterial solute-binding protein 9 family
BWEI_RS14120	COG0456	acetyltransferase
BWEI_RS14135	COG0523	cobalamin synthesis protein
BWEI_RS14140	COG4989	oxidoreductase activity
BWEI_RS14145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS14150	COG1231	oxidoreductase activity
BWEI_RS14160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWEI_RS14175	COG0783	Belongs to the Dps family
BWEI_RS14180	COG3949	Membrane
BWEI_RS14195	COG0840	transmembrane signaling receptor activity
BWEI_RS14225	COG0667	Aldo Keto reductase
BWEI_RS14230	COG0640	Transcriptional regulator
BWEI_RS14235	COG1404	Belongs to the peptidase S8 family
BWEI_RS14240	COG2002	toxin-antitoxin pair type II binding
BWEI_RS14245	COG0577	efflux transmembrane transporter activity
BWEI_RS14250	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BWEI_RS14280	COG1752	Esterase of the alpha-beta hydrolase superfamily
BWEI_RS14285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS14290	COG1279	arginine transmembrane transporter activity
BWEI_RS14295	COG2814	Major facilitator Superfamily
BWEI_RS14305	COG1082	Xylose isomerase domain protein TIM barrel
BWEI_RS14315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWEI_RS14335	COG1247	-acetyltransferase
BWEI_RS14340	COG1285	pathogenesis
BWEI_RS14360	COG5002	protein histidine kinase activity
BWEI_RS14365	COG0745	RESPONSE REGULATOR receiver
BWEI_RS14375	COG1316	TRANSCRIPTIONal
BWEI_RS14390	COG0083	homoserine kinase activity
BWEI_RS14400	COG0460	homoserine dehydrogenase
BWEI_RS14430	COG4122	O-methyltransferase activity
BWEI_RS14435	COG0300	oxidoreductase activity
BWEI_RS14440	COG5002	protein histidine kinase activity
BWEI_RS14445	COG0745	RESPONSE REGULATOR receiver
BWEI_RS14450	COG1132	(ABC) transporter
BWEI_RS14460	COG1388	LysM domain
BWEI_RS14460	COG0791	NLP P60 protein
BWEI_RS14475	COG1686	Belongs to the peptidase S11 family
BWEI_RS14505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BWEI_RS14510	COG4988	ABC transporter
BWEI_RS14515	COG1294	oxidase, subunit
BWEI_RS14520	COG1271	oxidase subunit
BWEI_RS14530	COG0346	lactoylglutathione lyase activity
BWEI_RS14545	COG1942	4-Oxalocrotonate Tautomerase
BWEI_RS14555	COG0583	DNA-binding transcription factor activity
BWEI_RS14575	COG0411	ABC transporter
BWEI_RS14585	COG0523	cobalamin synthesis protein
BWEI_RS14590	COG1231	oxidoreductase activity
BWEI_RS14605	COG0628	permease
BWEI_RS14625	COG0778	Nitroreductase
BWEI_RS14630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BWEI_RS14635	COG1959	2 iron, 2 sulfur cluster binding
BWEI_RS14640	COG0583	DNA-binding transcription factor activity
BWEI_RS14645	COG0697	spore germination
BWEI_RS14655	COG4549	nuclear export factor GLE1
BWEI_RS14660	COG2372	response to copper ion
BWEI_RS14660	COG1276	copper resistance
BWEI_RS14705	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS14715	COG1834	amidinotransferase
BWEI_RS14725	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS14745	COG0583	DNA-binding transcription factor activity
BWEI_RS14755	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BWEI_RS14765	COG2132	Multicopper oxidase
BWEI_RS14770	COG0006	proline dipeptidase activity
BWEI_RS14800	COG4846	Membrane protein involved in cytochrome C biogenesis
BWEI_RS14815	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BWEI_RS14820	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS14825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BWEI_RS14835	COG2390	Transcriptional regulator
BWEI_RS14840	COG4257	antibiotic catabolic process
BWEI_RS14855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BWEI_RS14865	COG1280	lysine exporter protein (LysE YggA)
BWEI_RS14885	COG0531	amino acid
BWEI_RS14895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BWEI_RS14905	COG1054	Belongs to the UPF0176 family
BWEI_RS14910	COG1914	H( )-stimulated, divalent metal cation uptake system
BWEI_RS14930	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS14955	COG4166	transmembrane transport
BWEI_RS14995	COG3384	dioxygenase
BWEI_RS15000	COG2814	Major facilitator Superfamily
BWEI_RS15025	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BWEI_RS15030	COG0129	dihydroxy-acid dehydratase activity
BWEI_RS15040	COG0745	RESPONSE REGULATOR receiver
BWEI_RS15045	COG5002	protein histidine kinase activity
BWEI_RS15055	COG2132	Multicopper oxidase
BWEI_RS15060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWEI_RS15080	COG2323	membrane
BWEI_RS15085	COG5566	PFAM Mor transcription activator
BWEI_RS15095	COG0733	neurotransmitter:sodium symporter activity
BWEI_RS15100	COG2244	polysaccharide biosynthetic process
BWEI_RS15115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWEI_RS15120	COG2223	nitrite transmembrane transporter activity
BWEI_RS15125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BWEI_RS15135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWEI_RS15140	COG0477	Major facilitator Superfamily
BWEI_RS15170	COG2814	Major facilitator Superfamily
BWEI_RS15185	COG1051	belongs to the nudix hydrolase family
BWEI_RS15220	COG2502	aspartate--ammonia ligase
BWEI_RS15230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWEI_RS15235	COG0784	Response regulator, receiver
BWEI_RS15240	COG4191	Histidine kinase
BWEI_RS15245	COG0281	malic enzyme
BWEI_RS15250	COG1027	Aspartate ammonia-lyase
BWEI_RS15260	COG0528	UMP kinase activity
BWEI_RS15265	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWEI_RS15280	COG1131	(ABC) transporter
BWEI_RS15315	COG2733	membrane
BWEI_RS15320	COG3048	D-serine ammonia-lyase activity
BWEI_RS15335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS15340	COG0785	Cytochrome C biogenesis protein
BWEI_RS15360	COG3340	Belongs to the peptidase S51 family
BWEI_RS15365	COG0534	Mate efflux family protein
BWEI_RS15385	COG0277	FAD linked oxidase domain protein
BWEI_RS15395	COG1757	Na H antiporter
BWEI_RS15400	COG0438	transferase activity, transferring glycosyl groups
BWEI_RS15400	COG1216	Glycosyl transferase, family 2
BWEI_RS15405	COG0697	spore germination
BWEI_RS15410	COG1802	Transcriptional regulator
BWEI_RS15440	COG0367	asparagine synthase
BWEI_RS15465	COG0406	alpha-ribazole phosphatase activity
BWEI_RS15510	COG3842	ATPase activity
BWEI_RS15515	COG0583	DNA-binding transcription factor activity
BWEI_RS15525	COG2814	Major facilitator Superfamily
BWEI_RS15540	COG3764	Sortase (surface protein transpeptidase)
BWEI_RS15545	COG3764	Sortase (surface protein transpeptidase)
BWEI_RS15560	COG2329	Antibiotic biosynthesis monooxygenase
BWEI_RS15590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWEI_RS15595	COG4786	Flagellar basal body rod
BWEI_RS15600	COG1419	protein localization to endoplasmic reticulum
BWEI_RS15605	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BWEI_RS15610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BWEI_RS15620	COG1987	bacterial-type flagellum assembly
BWEI_RS15625	COG1338	Plays a role in the flagellum-specific transport system
BWEI_RS15635	COG1776	CheC inhibitor of MCP methylation
BWEI_RS15635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWEI_RS15640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWEI_RS15650	COG0741	lytic transglycosylase activity
BWEI_RS15655	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWEI_RS15665	COG0489	protein tyrosine kinase activity
BWEI_RS15675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BWEI_RS15680	COG0314	molybdopterin synthase activity
BWEI_RS15685	COG0303	'Molybdopterin
BWEI_RS15690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWEI_RS15695	COG2116	formate transmembrane transporter activity
BWEI_RS15705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWEI_RS15710	COG5609	conserved protein (DUF2294)
BWEI_RS15715	COG2427	Protein of unknown function (DUF1641)
BWEI_RS15720	COG3383	formate dehydrogenase (NAD+) activity
BWEI_RS15730	COG0861	Integral membrane protein TerC family
BWEI_RS15750	COG0784	Response regulator, receiver
BWEI_RS15750	COG0835	chemotaxis
BWEI_RS15765	COG1749	Flagellar hook protein flgE
BWEI_RS15785	COG1157	protein secretion by the type III secretion system
BWEI_RS15795	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWEI_RS15800	COG1766	The M ring may be actively involved in energy transduction
BWEI_RS15810	COG1558	bacterial-type flagellum-dependent cell motility
BWEI_RS15815	COG1815	bacterial-type flagellum-dependent cell motility
BWEI_RS15840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BWEI_RS15845	COG1256	bacterial-type flagellum assembly
BWEI_RS15865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWEI_RS15880	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BWEI_RS15880	COG1776	CheC inhibitor of MCP methylation
BWEI_RS15885	COG0643	Histidine kinase
BWEI_RS15885	COG2198	Histidine kinase
BWEI_RS15890	COG2201	protein-glutamate methylesterase activity
BWEI_RS15895	COG1360	Flagellar Motor Protein
BWEI_RS15900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BWEI_RS15910	COG1923	regulation of RNA biosynthetic process
BWEI_RS15925	COG2814	Major facilitator Superfamily
BWEI_RS15945	COG2801	Transposase and inactivated derivatives
BWEI_RS15960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BWEI_RS15965	COG2323	membrane
BWEI_RS15975	COG4978	Transcriptional regulator
BWEI_RS15975	COG0789	Transcriptional regulator
BWEI_RS15980	COG0475	glutathione-regulated potassium exporter activity
BWEI_RS15990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BWEI_RS15995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWEI_RS16000	COG3162	membrane
BWEI_RS16015	COG1280	lysine exporter protein (LysE YggA)
BWEI_RS16020	COG3403	YqcI/YcgG family
BWEI_RS16050	COG0328	RNA-DNA hybrid ribonuclease activity
BWEI_RS16070	COG0454	-acetyltransferase
BWEI_RS16085	COG0438	transferase activity, transferring glycosyl groups
BWEI_RS16090	COG1215	transferase activity, transferring glycosyl groups
BWEI_RS16105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWEI_RS16125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BWEI_RS16155	COG2897	thiosulfate sulfurtransferase activity
BWEI_RS16165	COG0456	acetyltransferase
BWEI_RS16175	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BWEI_RS16180	COG2311	Membrane
BWEI_RS16185	COG2233	PERMEase
BWEI_RS16190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWEI_RS16195	COG0024	Methionine aminopeptidase
BWEI_RS16205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BWEI_RS16210	COG1199	ATP-dependent helicase activity
BWEI_RS16220	COG0116	Belongs to the methyltransferase superfamily
BWEI_RS16225	COG3599	regulation of cell shape
BWEI_RS16230	COG4474	Belongs to the UPF0398 family
BWEI_RS16265	COG3331	DNA recombination
BWEI_RS16270	COG4499	WXG100 protein secretion system (Wss), protein YukC
BWEI_RS16270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWEI_RS16280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BWEI_RS16285	COG3935	DnaD domain protein
BWEI_RS16300	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BWEI_RS16300	COG1199	ATP-dependent helicase activity
BWEI_RS16310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BWEI_RS16315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BWEI_RS16325	COG0617	tRNA 3'-terminal CCA addition
BWEI_RS16330	COG0438	transferase activity, transferring glycosyl groups
BWEI_RS16335	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BWEI_RS16340	COG1803	Methylglyoxal synthase
BWEI_RS16345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BWEI_RS16350	COG1694	Mazg nucleotide pyrophosphohydrolase
BWEI_RS16355	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS16365	COG2738	Putative neutral zinc metallopeptidase
BWEI_RS16380	COG4347	Protein of unknown function (DUF1405)
BWEI_RS16395	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BWEI_RS16410	COG5582	Belongs to the UPF0302 family
BWEI_RS16415	COG0457	Tetratricopeptide repeat
BWEI_RS16420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BWEI_RS16430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BWEI_RS16445	COG0142	geranyltranstransferase activity
BWEI_RS16450	COG2226	methyltransferase
BWEI_RS16455	COG0142	geranyltranstransferase activity
BWEI_RS16460	COG0302	gtp cyclohydrolase
BWEI_RS16470	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BWEI_RS16490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BWEI_RS16495	COG1160	GTP binding
BWEI_RS16520	COG1304	FMN binding
BWEI_RS16530	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BWEI_RS16535	COG0252	asparaginase activity
BWEI_RS16540	COG0492	ferredoxin-NADP+ reductase activity
BWEI_RS16560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BWEI_RS16575	COG1408	metallophosphoesterase
BWEI_RS16585	COG1266	CAAX protease self-immunity
BWEI_RS16590	COG0514	ATP-dependent DNA helicase (RecQ)
BWEI_RS16595	COG4955	Helix-turn-helix domain
BWEI_RS16600	COG1141	Ferredoxin
BWEI_RS16605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BWEI_RS16615	COG4942	peptidase
BWEI_RS16620	COG2096	Adenosyltransferase
BWEI_RS16625	COG5002	protein histidine kinase activity
BWEI_RS16630	COG0745	RESPONSE REGULATOR receiver
BWEI_RS16635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BWEI_RS16640	COG1333	cytochrome c biogenesis protein
BWEI_RS16650	COG1187	pseudouridine synthase activity
BWEI_RS16655	COG0700	Nucleoside recognition
BWEI_RS16660	COG2715	membrane protein required for spore maturation
BWEI_RS16665	COG1686	Belongs to the peptidase S11 family
BWEI_RS16670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWEI_RS16685	COG0392	lysyltransferase activity
BWEI_RS16685	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BWEI_RS16700	COG5002	protein histidine kinase activity
BWEI_RS16705	COG0582	viral genome integration into host DNA
BWEI_RS16715	COG1801	Protein of unknown function DUF72
BWEI_RS16720	COG3852	Histidine kinase
BWEI_RS16735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWEI_RS16740	COG1392	Phosphate transport regulator
BWEI_RS16745	COG0306	phosphate transporter
BWEI_RS16750	COG0730	response to heat
BWEI_RS16790	COG2226	methyltransferase
BWEI_RS16800	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS16810	COG2197	response regulator
BWEI_RS16815	COG4585	Histidine kinase
BWEI_RS16820	COG4758	membrane
BWEI_RS16840	COG1757	Na H antiporter
BWEI_RS16860	COG0733	neurotransmitter:sodium symporter activity
BWEI_RS16865	COG1648	precorrin-2 dehydrogenase activity
BWEI_RS16885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BWEI_RS16890	COG0529	Catalyzes the synthesis of activated sulfate
BWEI_RS16895	COG2046	Belongs to the sulfate adenylyltransferase family
BWEI_RS16900	COG0175	sulfate reduction
BWEI_RS16905	COG0019	diaminopimelate decarboxylase activity
BWEI_RS16915	COG1368	sulfuric ester hydrolase activity
BWEI_RS16920	COG1183	phosphatidylcholine synthase activity
BWEI_RS16930	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BWEI_RS16935	COG0140	phosphoribosyl-ATP diphosphatase activity
BWEI_RS16945	COG0107	imidazoleglycerol-phosphate synthase activity
BWEI_RS16950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BWEI_RS16955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BWEI_RS16960	COG0131	Imidazoleglycerol-phosphate dehydratase
BWEI_RS16970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BWEI_RS16975	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BWEI_RS16985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BWEI_RS16995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BWEI_RS17005	COG0440	acetolactate synthase activity
BWEI_RS17010	COG0028	Belongs to the TPP enzyme family
BWEI_RS17015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWEI_RS17035	COG3874	Sporulation protein YtfJ
BWEI_RS17045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWEI_RS17050	COG1301	dicarboxylic acid transport
BWEI_RS17060	COG1846	Transcriptional regulator
BWEI_RS17080	COG1968	undecaprenyl-diphosphatase activity
BWEI_RS17085	COG0534	Mate efflux family protein
BWEI_RS17120	COG0716	FMN binding
BWEI_RS17140	COG1696	Membrane protein involved in D-alanine export
BWEI_RS17145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BWEI_RS17150	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BWEI_RS17155	COG2070	2-Nitropropane dioxygenase
BWEI_RS17160	COG1619	proteins homologs of microcin C7 resistance protein MccF
BWEI_RS17170	COG1335	isochorismatase
BWEI_RS17180	COG1522	sequence-specific DNA binding
BWEI_RS17190	COG1266	CAAX protease self-immunity
BWEI_RS17195	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BWEI_RS17200	COG1131	(ABC) transporter
BWEI_RS17210	COG1131	(ABC) transporter
BWEI_RS17215	COG1725	Transcriptional regulator
BWEI_RS17225	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS17230	COG2204	response regulator
BWEI_RS17245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BWEI_RS17250	COG0531	amino acid
BWEI_RS17255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWEI_RS17260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWEI_RS17265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BWEI_RS17270	COG1780	Probably involved in ribonucleotide reductase function
BWEI_RS17285	COG0456	acetyltransferase
BWEI_RS17300	COG4873	Protein conserved in bacteria
BWEI_RS17305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BWEI_RS17315	COG0720	synthase
BWEI_RS17320	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BWEI_RS17325	COG5002	protein histidine kinase activity
BWEI_RS17335	COG2318	DinB family
BWEI_RS17345	COG1846	Transcriptional regulator
BWEI_RS17350	COG3852	Histidine kinase
BWEI_RS17360	COG2861	carbohydrate metabolic process
BWEI_RS17370	COG0235	Class ii aldolase
BWEI_RS17380	COG1349	DNA-binding transcription factor activity
BWEI_RS17390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BWEI_RS17395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BWEI_RS17405	COG3842	ATPase activity
BWEI_RS17410	COG1840	ABC-type Fe3 transport system, periplasmic component
BWEI_RS17425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWEI_RS17435	COG3243	poly(R)-hydroxyalkanoic acid synthase
BWEI_RS17440	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS17460	COG2030	dehydratase
BWEI_RS17470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BWEI_RS17475	COG0861	Integral membrane protein TerC family
BWEI_RS17480	COG2116	formate transmembrane transporter activity
BWEI_RS17490	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BWEI_RS17495	COG1556	Lactate utilization protein
BWEI_RS17500	COG1139	Iron-sulfur cluster binding protein
BWEI_RS17505	COG0247	lactate metabolic process
BWEI_RS17510	COG2186	Transcriptional regulator
BWEI_RS17515	COG5002	protein histidine kinase activity
BWEI_RS17520	COG0745	RESPONSE REGULATOR receiver
BWEI_RS17530	COG3835	regulator
BWEI_RS17535	COG0277	FAD linked oxidase domain protein
BWEI_RS17540	COG0247	lactate metabolic process
BWEI_RS17545	COG2340	Cysteine-rich secretory protein family
BWEI_RS17555	COG0564	pseudouridine synthase activity
BWEI_RS17565	COG2409	Drug exporters of the RND superfamily
BWEI_RS17575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BWEI_RS17580	COG1177	transmembrane transport
BWEI_RS17585	COG1176	ABC-type spermidine putrescine transport system, permease component I
BWEI_RS17595	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS17630	COG0681	Belongs to the peptidase S26 family
BWEI_RS17635	COG1686	Belongs to the peptidase S11 family
BWEI_RS17680	COG1476	TRANSCRIPTIONal
BWEI_RS17685	COG0567	Dehydrogenase, E1 component
BWEI_RS17690	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWEI_RS17710	COG2226	methyltransferase
BWEI_RS17755	COG5634	Uncharacterized conserved protein (DUF2278)
BWEI_RS17760	COG1620	l-lactate permease
BWEI_RS17770	COG0159	tryptophan synthase activity
BWEI_RS17775	COG0133	tryptophan synthase activity
BWEI_RS17780	COG0135	phosphoribosylanthranilate isomerase activity
BWEI_RS17785	COG0134	indole-3-glycerol-phosphate synthase activity
BWEI_RS17790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BWEI_RS17795	COG0512	Glutamine amidotransferase of anthranilate synthase
BWEI_RS17795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BWEI_RS17810	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWEI_RS17815	COG5492	domain, Protein
BWEI_RS17840	COG2382	esterase
BWEI_RS17845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BWEI_RS17850	COG2153	protein acetylation
BWEI_RS17895	COG1091	dTDP-4-dehydrorhamnose reductase activity
BWEI_RS17910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BWEI_RS17930	COG0457	Tetratricopeptide repeat
BWEI_RS17930	COG0463	Glycosyl transferase, family 2
BWEI_RS17950	COG1216	Glycosyl transferase, family 2
BWEI_RS17955	COG0772	Belongs to the SEDS family
BWEI_RS17960	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BWEI_RS17970	COG0564	pseudouridine synthase activity
BWEI_RS17980	COG2357	RelA SpoT domain protein
BWEI_RS17990	COG4116	CYTH
BWEI_RS17995	COG2346	COG2346, Truncated hemoglobins
BWEI_RS18005	COG1164	Oligoendopeptidase f
BWEI_RS18015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWEI_RS18020	COG4862	establishment of competence for transformation
BWEI_RS18025	COG0861	Integral membrane protein TerC family
BWEI_RS18040	COG4166	transmembrane transport
BWEI_RS18045	COG0534	Mate efflux family protein
BWEI_RS18050	COG4608	Belongs to the ABC transporter superfamily
BWEI_RS18055	COG0444	Belongs to the ABC transporter superfamily
BWEI_RS18060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWEI_RS18065	COG0601	transmembrane transport
BWEI_RS18070	COG4166	transmembrane transport
BWEI_RS18080	COG0180	Tryptophanyl-tRNA synthetase
BWEI_RS18095	COG5504	Zn-dependent protease
BWEI_RS18100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BWEI_RS18105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWEI_RS18120	COG2267	carboxylic ester hydrolase activity
BWEI_RS18140	COG0561	phosphatase activity
BWEI_RS18155	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS18160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BWEI_RS18185	COG1329	Transcriptional regulator
BWEI_RS18200	COG2996	Protein conserved in bacteria
BWEI_RS18205	COG1666	GTP binding
BWEI_RS18215	COG0004	ammonium transporteR
BWEI_RS18220	COG0753	catalase activity
BWEI_RS18230	COG0367	asparagine synthase
BWEI_RS18255	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWEI_RS18305	COG1074	ATP-dependent DNA helicase activity
BWEI_RS18310	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BWEI_RS18320	COG0398	Pfam SNARE associated Golgi protein
BWEI_RS18325	COG4903	ComK protein
BWEI_RS18340	COG1278	Cold shock
BWEI_RS18350	COG2224	Isocitrate lyase
BWEI_RS18355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BWEI_RS18375	COG0697	spore germination
BWEI_RS18380	COG0501	Belongs to the peptidase M48B family
BWEI_RS18395	COG0745	RESPONSE REGULATOR receiver
BWEI_RS18400	COG2205	protein histidine kinase activity
BWEI_RS18405	COG2207	Transcriptional regulator
BWEI_RS18405	COG3708	Transcriptional regulator
BWEI_RS18410	COG1595	DNA-templated transcription, initiation
BWEI_RS18425	COG1078	dGTPase activity
BWEI_RS18430	COG1408	metallophosphoesterase
BWEI_RS18470	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS18480	COG0095	Lipoate-protein ligase
BWEI_RS18485	COG1234	tRNA 3'-trailer cleavage
BWEI_RS18490	COG1609	Transcriptional regulator
BWEI_RS18525	COG1511	domain protein
BWEI_RS18525	COG1511	domain protein
BWEI_RS18530	COG1309	transcriptional regulator
BWEI_RS18550	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BWEI_RS18555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BWEI_RS18560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BWEI_RS18565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWEI_RS18570	COG2329	Antibiotic biosynthesis monooxygenase
BWEI_RS18575	COG3428	Bacterial PH domain
BWEI_RS18580	COG3402	PFAM membrane-flanked domain
BWEI_RS18620	COG3428	Bacterial PH domain
BWEI_RS18625	COG3402	PFAM membrane-flanked domain
BWEI_RS18655	COG1556	Lactate utilization protein
BWEI_RS18660	COG1139	Iron-sulfur cluster binding protein
BWEI_RS18665	COG0247	lactate metabolic process
BWEI_RS18675	COG4473	ABC transporter
BWEI_RS18680	COG1131	(ABC) transporter
BWEI_RS18685	COG0537	adenosine 5'-monophosphoramidase activity
BWEI_RS18695	COG1846	Transcriptional regulator
BWEI_RS18715	COG3973	AAA domain
BWEI_RS18730	COG1595	DNA-templated transcription, initiation
BWEI_RS18735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BWEI_RS18740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BWEI_RS18745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BWEI_RS18750	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BWEI_RS18755	COG3620	sequence-specific DNA binding
BWEI_RS18770	COG2267	carboxylic ester hydrolase activity
BWEI_RS18780	COG0457	Tetratricopeptide repeat
BWEI_RS18785	COG0346	lactoylglutathione lyase activity
BWEI_RS18790	COG0346	lactoylglutathione lyase activity
BWEI_RS18800	COG3481	metal-dependent phosphohydrolase, HD sub domain
BWEI_RS18805	COG4717	serine-type aminopeptidase activity
BWEI_RS18810	COG0420	3'-5' exonuclease activity
BWEI_RS18830	COG2197	response regulator
BWEI_RS18835	COG4585	Histidine kinase
BWEI_RS18855	COG2186	Transcriptional regulator
BWEI_RS18860	COG2807	transmembrane transport
BWEI_RS18885	COG2205	protein histidine kinase activity
BWEI_RS18885	COG5002	protein histidine kinase activity
BWEI_RS18885	COG0784	Response regulator, receiver
BWEI_RS18890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BWEI_RS18895	COG2208	phosphoserine phosphatase activity
BWEI_RS18905	COG1191	sigma factor activity
BWEI_RS18910	COG2172	sigma factor antagonist activity
BWEI_RS18930	COG3237	CsbD-like
BWEI_RS18970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWEI_RS19020	COG2720	vancomycin resistance protein
BWEI_RS19030	COG0457	Tetratricopeptide repeat
BWEI_RS19045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BWEI_RS19075	COG2376	Dihydroxyacetone kinase
BWEI_RS19095	COG1183	phosphatidylcholine synthase activity
BWEI_RS19105	COG2723	6-phospho-beta-galactosidase activity
BWEI_RS19110	COG1263	PTS System
BWEI_RS19110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS19110	COG2190	(PTS) system
BWEI_RS19115	COG3711	transcriptional antiterminator
BWEI_RS19120	COG2801	Transposase and inactivated derivatives
BWEI_RS19140	COG0640	Transcriptional regulator
BWEI_RS19145	COG2814	Major facilitator Superfamily
BWEI_RS19150	COG2732	(Barnase) inhibitor
BWEI_RS19210	COG0477	Major facilitator Superfamily
BWEI_RS19235	COG0305	Participates in initiation and elongation during chromosome replication
BWEI_RS19265	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BWEI_RS19285	COG3181	Tripartite tricarboxylate transporter family receptor
BWEI_RS19290	COG4565	transcriptional regulatory protein
BWEI_RS19295	COG3290	protein histidine kinase activity
BWEI_RS19300	COG0477	Major facilitator Superfamily
BWEI_RS19315	COG4608	Belongs to the ABC transporter superfamily
BWEI_RS19320	COG0444	Belongs to the ABC transporter superfamily
BWEI_RS19325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWEI_RS19330	COG0601	transmembrane transport
BWEI_RS19365	COG0579	oxidoreductase
BWEI_RS19380	COG2318	DinB family
BWEI_RS19395	COG1363	Peptidase, m42
BWEI_RS19410	COG1024	Enoyl-CoA hydratase
BWEI_RS19435	COG4196	transglutaminase domain protein
BWEI_RS19440	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS19450	COG2244	polysaccharide biosynthetic process
BWEI_RS19455	COG0653	protein targeting
BWEI_RS19470	COG0659	secondary active sulfate transmembrane transporter activity
BWEI_RS19480	COG4978	Transcriptional regulator
BWEI_RS19480	COG0789	Transcriptional regulator
BWEI_RS19490	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS19495	COG0318	PFAM AMP-dependent synthetase and ligase
BWEI_RS19500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BWEI_RS19505	COG3409	Peptidoglycan-binding domain 1 protein
BWEI_RS19505	COG5632	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS19510	COG0561	phosphatase activity
BWEI_RS19515	COG2094	Belongs to the DNA glycosylase MPG family
BWEI_RS19520	COG1216	Glycosyl transferase, family 2
BWEI_RS19525	COG0463	Glycosyl transferase, family 2
BWEI_RS19530	COG3527	Alpha-acetolactate decarboxylase
BWEI_RS19535	COG0028	Belongs to the TPP enzyme family
BWEI_RS19550	COG3679	Belongs to the UPF0342 family
BWEI_RS19555	COG4399	Belongs to the UPF0754 family
BWEI_RS19565	COG0189	ligase activity
BWEI_RS19580	COG1126	abc transporter atp-binding protein
BWEI_RS19585	COG0765	amino acid transport
BWEI_RS19590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS19595	COG1132	(ABC) transporter
BWEI_RS19600	COG1132	(ABC) transporter
BWEI_RS19605	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS19610	COG0531	amino acid
BWEI_RS19620	COG0693	protein deglycase activity
BWEI_RS19645	COG1733	regulation of RNA biosynthetic process
BWEI_RS19650	COG2814	Major facilitator Superfamily
BWEI_RS19655	COG1309	transcriptional regulator
BWEI_RS19660	COG2076	Multidrug Resistance protein
BWEI_RS19675	COG0300	oxidoreductase activity
BWEI_RS19685	COG1522	sequence-specific DNA binding
BWEI_RS19690	COG0697	spore germination
BWEI_RS19710	COG2259	Doxx family
BWEI_RS19720	COG1263	PTS System
BWEI_RS19720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS19725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BWEI_RS19730	COG1737	Transcriptional regulator
BWEI_RS19740	COG0475	glutathione-regulated potassium exporter activity
BWEI_RS19745	COG0531	amino acid
BWEI_RS19775	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS19800	COG3546	catalase activity
BWEI_RS19805	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS19810	COG0577	efflux transmembrane transporter activity
BWEI_RS19825	COG5522	Integral membrane protein (intg_mem_TP0381)
BWEI_RS19835	COG1136	(ABC) transporter
BWEI_RS19840	COG0577	efflux transmembrane transporter activity
BWEI_RS19845	COG3584	3D domain protein
BWEI_RS19845	COG1388	LysM domain
BWEI_RS19865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWEI_RS19870	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWEI_RS19875	COG3711	transcriptional antiterminator
BWEI_RS19875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWEI_RS19885	COG2814	Major facilitator Superfamily
BWEI_RS19895	COG1283	sodium-dependent phosphate transmembrane transporter activity
BWEI_RS19900	COG0604	alcohol dehydrogenase
BWEI_RS19905	COG1316	TRANSCRIPTIONal
BWEI_RS19915	COG0730	response to heat
BWEI_RS19920	COG2210	Belongs to the sulfur carrier protein TusA family
BWEI_RS19925	COG0425	Belongs to the sulfur carrier protein TusA family
BWEI_RS19925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS19930	COG0425	Belongs to the sulfur carrier protein TusA family
BWEI_RS19935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS19935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS19940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BWEI_RS19940	COG0425	Belongs to the sulfur carrier protein TusA family
BWEI_RS19945	COG1937	Protein conserved in bacteria
BWEI_RS19970	COG2719	SpoVR family
BWEI_RS19975	COG0778	Nitroreductase
BWEI_RS20035	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS20040	COG2252	PERMEase
BWEI_RS20050	COG1846	Transcriptional regulator
BWEI_RS20055	COG2814	Major facilitator Superfamily
BWEI_RS20060	COG2205	protein histidine kinase activity
BWEI_RS20065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BWEI_RS20070	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BWEI_RS20100	COG0351	phosphomethylpyrimidine kinase
BWEI_RS20105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BWEI_RS20115	COG2104	thiamine diphosphate biosynthetic process
BWEI_RS20120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWEI_RS20125	COG0352	thiamine-phosphate diphosphorylase activity
BWEI_RS20130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWEI_RS20135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWEI_RS20140	COG1116	anion transmembrane transporter activity
BWEI_RS20145	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BWEI_RS20150	COG3103	Sh3 type 3 domain protein
BWEI_RS20150	COG4991	sh3 domain protein
BWEI_RS20150	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS20165	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BWEI_RS20210	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BWEI_RS20215	COG0187	DNA topoisomerase II activity
BWEI_RS20220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BWEI_RS20225	COG2501	S4 domain
BWEI_RS20230	COG0592	DNA-directed DNA polymerase activity
BWEI_RS20235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BWEI_RS20240	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BWEI_RS20245	COG0594	ribonuclease P activity
BWEI_RS20250	COG0706	membrane insertase activity
BWEI_RS20255	COG1847	R3H domain protein
BWEI_RS20260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BWEI_RS20265	COG0445	tRNA wobble uridine modification
BWEI_RS20270	COG0357	Ribosomal RNA small subunit methyltransferase G
BWEI_RS20275	COG1475	DNA binding
BWEI_RS20280	COG1192	Involved in chromosome partitioning
BWEI_RS20285	COG1475	DNA binding
BWEI_RS20295	COG0668	transmembrane transport
BWEI_RS20300	COG4481	Protein conserved in bacteria
BWEI_RS20305	COG0012	GTP binding
BWEI_RS20310	COG0360	Binds together with S18 to 16S ribosomal RNA
BWEI_RS20315	COG0629	single-stranded DNA binding
BWEI_RS20325	COG4241	membrane
BWEI_RS20330	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BWEI_RS20335	COG0359	binds to the 23S rRNA
BWEI_RS20340	COG0305	Participates in initiation and elongation during chromosome replication
BWEI_RS20370	COG0745	RESPONSE REGULATOR receiver
BWEI_RS20375	COG5002	protein histidine kinase activity
BWEI_RS20385	COG4853	Protein conserved in bacteria
BWEI_RS20390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BWEI_RS20395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWEI_RS20405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BWEI_RS20415	COG1164	Oligoendopeptidase f
BWEI_RS20440	COG1272	protein, Hemolysin III
BWEI_RS20445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BWEI_RS20495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BWEI_RS20500	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BWEI_RS20505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWEI_RS20510	COG2814	Major facilitator Superfamily
BWEI_RS20515	COG3275	phosphorelay sensor kinase activity
BWEI_RS20520	COG3279	Response regulator of the LytR AlgR family
BWEI_RS20525	COG1380	Effector of murein hydrolase LrgA
BWEI_RS20535	COG0628	permease
BWEI_RS20540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWEI_RS20540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BWEI_RS20545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWEI_RS20550	COG1309	transcriptional regulator
BWEI_RS20555	COG0488	(ABC) transporter
BWEI_RS20560	COG1309	transcriptional regulator
BWEI_RS20570	COG0463	Glycosyl transferase, family 2
BWEI_RS20575	COG4485	Bacterial membrane protein, YfhO
BWEI_RS20585	COG1216	Glycosyl transferase, family 2
BWEI_RS20595	COG1216	Glycosyl transferase, family 2
BWEI_RS20600	COG1607	acyl-coa hydrolase
BWEI_RS20610	COG0840	transmembrane signaling receptor activity
BWEI_RS20635	COG0477	Major facilitator Superfamily
BWEI_RS20640	COG3279	Response regulator of the LytR AlgR family
BWEI_RS20645	COG1966	Carbon starvation protein
BWEI_RS20650	COG2879	small protein
BWEI_RS20655	COG3706	GGDEF domain
BWEI_RS20660	COG0351	phosphomethylpyrimidine kinase
BWEI_RS20665	COG4585	Histidine kinase
BWEI_RS20665	COG2203	Gaf domain
BWEI_RS20670	COG2197	response regulator
BWEI_RS20680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BWEI_RS20685	COG1011	Hydrolase
BWEI_RS20695	COG2873	o-acetylhomoserine
BWEI_RS20700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BWEI_RS20705	COG0460	homoserine dehydrogenase
BWEI_RS20715	COG1609	Transcriptional regulator
BWEI_RS20720	COG2755	lipolytic protein G-D-S-L family
BWEI_RS20725	COG1131	(ABC) transporter
BWEI_RS20730	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BWEI_RS20735	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BWEI_RS20740	COG2814	Major facilitator Superfamily
BWEI_RS20745	COG0561	phosphatase activity
BWEI_RS20750	COG2233	PERMEase
BWEI_RS20765	COG2363	Small membrane protein
BWEI_RS20775	COG3773	Cell wall hydrolase
BWEI_RS20785	COG3253	May function as heme-dependent peroxidase
BWEI_RS20790	COG0280	phosphate acetyltransferase
BWEI_RS20805	COG4844	belongs to the
BWEI_RS20810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS20815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS20820	COG1120	ATPase activity
BWEI_RS20825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS20830	COG1078	dGTPase activity
BWEI_RS20840	COG1994	Peptidase M50
BWEI_RS20850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BWEI_RS20855	COG0584	glycerophosphoryl diester phosphodiesterase
BWEI_RS20860	COG0789	Transcriptional regulator
BWEI_RS20865	COG2814	Major facilitator Superfamily
BWEI_RS20870	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BWEI_RS20875	COG0010	Belongs to the arginase family
BWEI_RS20890	COG1619	proteins homologs of microcin C7 resistance protein MccF
BWEI_RS20895	COG4506	Protein conserved in bacteria
BWEI_RS20915	COG2234	aminopeptidase activity
BWEI_RS20920	COG0024	Methionine aminopeptidase
BWEI_RS20925	COG1131	(ABC) transporter
BWEI_RS20930	COG0842	Transport permease protein
BWEI_RS20935	COG4585	Histidine kinase
BWEI_RS20940	COG2197	response regulator
BWEI_RS20945	COG3227	Zinc metalloprotease (Elastase)
BWEI_RS20960	COG3300	MHYT domain
BWEI_RS20960	COG5001	Diguanylate cyclase
BWEI_RS20965	COG4294	response to UV
BWEI_RS20970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BWEI_RS20975	COG2181	nitrate reductase activity
BWEI_RS20975	COG0247	lactate metabolic process
BWEI_RS20980	COG0183	Belongs to the thiolase family
BWEI_RS20985	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWEI_RS20990	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS20995	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS21005	COG3343	RNA polymerase activity
BWEI_RS21010	COG0504	CTP synthase activity
BWEI_RS21015	COG4821	SIS domain
BWEI_RS21035	COG1494	fructose-1,6-bisphosphatase
BWEI_RS21040	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BWEI_RS21055	COG1435	thymidine kinase activity
BWEI_RS21060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BWEI_RS21065	COG2890	protein-(glutamine-N5) methyltransferase activity
BWEI_RS21080	COG0009	L-threonylcarbamoyladenylate synthase
BWEI_RS21085	COG1971	Probably functions as a manganese efflux pump
BWEI_RS21095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BWEI_RS21100	COG2259	Doxx family
BWEI_RS21105	COG2190	(PTS) system
BWEI_RS21115	COG0698	ribose 5-phosphate isomerase
BWEI_RS21150	COG0356	it plays a direct role in the translocation of protons across the membrane
BWEI_RS21160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BWEI_RS21165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BWEI_RS21180	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BWEI_RS21185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BWEI_RS21205	COG3300	MHYT domain
BWEI_RS21205	COG5001	Diguanylate cyclase
BWEI_RS21210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWEI_RS21215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWEI_RS21220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWEI_RS21225	COG0649	NAD binding
BWEI_RS21230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BWEI_RS21240	COG0839	Belongs to the complex I subunit 6 family
BWEI_RS21245	COG0713	ATP synthesis coupled electron transport
BWEI_RS21250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BWEI_RS21255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BWEI_RS21260	COG1007	ATP synthesis coupled electron transport
BWEI_RS21265	COG4836	Membrane
BWEI_RS21280	COG2385	sporulation resulting in formation of a cellular spore
BWEI_RS21305	COG3279	Response regulator of the LytR AlgR family
BWEI_RS21320	COG0739	heme binding
BWEI_RS21330	COG1609	Transcriptional regulator
BWEI_RS21345	COG0489	protein tyrosine kinase activity
BWEI_RS21350	COG3944	biosynthesis protein
BWEI_RS21355	COG0489	protein tyrosine kinase activity
BWEI_RS21360	COG4464	protein tyrosine phosphatase activity
BWEI_RS21365	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWEI_RS21370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWEI_RS21375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWEI_RS21400	COG1215	transferase activity, transferring glycosyl groups
BWEI_RS21425	COG0745	RESPONSE REGULATOR receiver
BWEI_RS21430	COG5002	protein histidine kinase activity
BWEI_RS21430	COG3850	Histidine kinase
BWEI_RS21445	COG2271	Major facilitator Superfamily
BWEI_RS21470	COG1136	(ABC) transporter
BWEI_RS21475	COG0577	efflux transmembrane transporter activity
BWEI_RS21515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BWEI_RS21520	COG4715	Zinc finger, swim domain protein
BWEI_RS21545	COG3584	3D domain protein
BWEI_RS21545	COG1388	LysM domain
BWEI_RS21550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BWEI_RS21555	COG1215	transferase activity, transferring glycosyl groups
BWEI_RS21565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS21570	COG1388	LysM domain
BWEI_RS21570	COG0791	NLP P60 protein
BWEI_RS21580	COG1368	sulfuric ester hydrolase activity
BWEI_RS21590	COG2389	metal-binding protein
BWEI_RS21600	COG1620	l-lactate permease
BWEI_RS21605	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BWEI_RS21610	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BWEI_RS21615	COG1294	oxidase, subunit
BWEI_RS21620	COG1271	oxidase subunit
BWEI_RS21625	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BWEI_RS21630	COG0583	DNA-binding transcription factor activity
BWEI_RS21635	COG1511	domain protein
BWEI_RS21650	COG1301	dicarboxylic acid transport
BWEI_RS21655	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWEI_RS21665	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWEI_RS21685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BWEI_RS21690	COG1447	Phosphotransferase system cellobiose-specific component IIA
BWEI_RS21695	COG1486	melibiose metabolic process
BWEI_RS21715	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BWEI_RS21715	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BWEI_RS21725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BWEI_RS21730	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWEI_RS21735	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BWEI_RS21740	COG1316	TRANSCRIPTIONal
BWEI_RS21745	COG1739	Uncharacterized protein family UPF0029
BWEI_RS21750	COG1307	EDD domain protein, DegV family
BWEI_RS21755	COG1733	regulation of RNA biosynthetic process
BWEI_RS21760	COG0791	NLP P60 protein
BWEI_RS21760	COG1388	LysM domain
BWEI_RS21765	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BWEI_RS21770	COG1040	competence protein
BWEI_RS21775	COG1278	Cold shock
BWEI_RS21795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BWEI_RS21805	COG2884	Cell division ATP-binding protein ftsE
BWEI_RS21810	COG2177	Part of the ABC transporter FtsEX involved in
BWEI_RS21815	COG3409	Peptidoglycan-binding domain 1 protein
BWEI_RS21815	COG0793	Belongs to the peptidase S41A family
BWEI_RS21820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BWEI_RS21825	COG1132	(ABC) transporter
BWEI_RS21835	COG0488	(ABC) transporter
BWEI_RS21840	COG0655	NAD(P)H dehydrogenase (quinone) activity
BWEI_RS21845	COG0789	Transcriptional regulator
BWEI_RS21850	COG0583	DNA-binding transcription factor activity
BWEI_RS21885	COG0789	Transcriptional regulator
BWEI_RS21905	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BWEI_RS21920	COG1950	PFAM Membrane protein of
BWEI_RS21925	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BWEI_RS21930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BWEI_RS21935	COG0546	phosphoglycolate phosphatase activity
BWEI_RS21940	COG0110	maltose O-acetyltransferase activity
BWEI_RS21945	COG0457	Tetratricopeptide repeat
BWEI_RS21950	COG0492	ferredoxin-NADP+ reductase activity
BWEI_RS21960	COG1051	belongs to the nudix hydrolase family
BWEI_RS21965	COG1660	Displays ATPase and GTPase activities
BWEI_RS21970	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BWEI_RS21975	COG1481	regulation of sporulation
BWEI_RS21980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BWEI_RS21990	COG2323	membrane
BWEI_RS22005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BWEI_RS22035	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BWEI_RS22050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BWEI_RS22055	COG0126	phosphoglycerate kinase activity
BWEI_RS22060	COG0149	triose-phosphate isomerase activity
BWEI_RS22070	COG0148	phosphopyruvate hydratase activity
BWEI_RS22085	COG1346	cytolysis
BWEI_RS22090	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWEI_RS22095	COG1647	Serine aminopeptidase, S33
BWEI_RS22100	COG0557	exoribonuclease II activity
BWEI_RS22105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BWEI_RS22140	COG2233	PERMEase
BWEI_RS22145	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BWEI_RS22150	COG0288	reversible hydration of carbon dioxide
BWEI_RS22155	COG1522	sequence-specific DNA binding
BWEI_RS22160	COG1733	regulation of RNA biosynthetic process
BWEI_RS22170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BWEI_RS22200	COG0840	transmembrane signaling receptor activity
BWEI_RS22200	COG3290	protein histidine kinase activity
BWEI_RS22220	COG1252	NADH dehydrogenase
BWEI_RS22230	COG1733	regulation of RNA biosynthetic process
BWEI_RS22235	COG2814	Major facilitator Superfamily
BWEI_RS22240	COG0656	L-ascorbic acid biosynthetic process
BWEI_RS22255	COG2910	NAD(P)H-binding
BWEI_RS22260	COG1115	amino acid carrier protein
BWEI_RS22265	COG1115	amino acid carrier protein
BWEI_RS22270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS22275	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS22280	COG2311	Membrane
BWEI_RS22285	COG1528	Iron-storage protein
BWEI_RS22295	COG1611	Belongs to the LOG family
BWEI_RS22305	COG2318	DinB family
BWEI_RS22320	COG0783	Belongs to the Dps family
BWEI_RS22325	COG1115	amino acid carrier protein
BWEI_RS22330	COG0490	domain, Protein
BWEI_RS22335	COG0475	glutathione-regulated potassium exporter activity
BWEI_RS22350	COG1741	Belongs to the pirin family
BWEI_RS22355	COG3227	Zinc metalloprotease (Elastase)
BWEI_RS22360	COG2151	metal-sulfur cluster biosynthetic enzyme
BWEI_RS22365	COG0840	transmembrane signaling receptor activity
BWEI_RS22370	COG0840	transmembrane signaling receptor activity
BWEI_RS22380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BWEI_RS22390	COG5002	protein histidine kinase activity
BWEI_RS22395	COG0745	RESPONSE REGULATOR receiver
BWEI_RS22400	COG1376	ErfK ybiS ycfS ynhG family protein
BWEI_RS22410	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS22435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS22455	COG0531	amino acid
BWEI_RS22460	COG2814	Major facilitator Superfamily
BWEI_RS22470	COG0840	transmembrane signaling receptor activity
BWEI_RS22475	COG0011	TIGRFAM Protein of
BWEI_RS22485	COG0506	proline dehydrogenase activity
BWEI_RS22490	COG1686	Belongs to the peptidase S11 family
BWEI_RS22495	COG1024	Enoyl-CoA hydratase
BWEI_RS22495	COG1250	3-hydroxyacyl-CoA dehydrogenase
BWEI_RS22500	COG0183	Belongs to the thiolase family
BWEI_RS22505	COG1960	acyl-CoA dehydrogenase activity
BWEI_RS22510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BWEI_RS22515	COG1309	transcriptional regulator
BWEI_RS22580	COG1393	Belongs to the ArsC family
BWEI_RS22585	COG0509	glycine decarboxylation via glycine cleavage system
BWEI_RS22595	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BWEI_RS22600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS22610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BWEI_RS22615	COG2011	ABC-type metal ion transport system permease component
BWEI_RS22620	COG1464	Belongs to the NlpA lipoprotein family
BWEI_RS22625	COG1464	Belongs to the NlpA lipoprotein family
BWEI_RS22630	COG0396	ATPase activity
BWEI_RS22635	COG0719	Fe-S assembly protein
BWEI_RS22640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BWEI_RS22645	COG0822	iron-sulfur transferase activity
BWEI_RS22650	COG0719	Fe-S assembly protein
BWEI_RS22655	COG0737	Belongs to the 5'-nucleotidase family
BWEI_RS22660	COG3377	Domain of unknown function (DUF1805)
BWEI_RS22670	COG0739	heme binding
BWEI_RS22675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BWEI_RS22695	COG4377	Putative membrane peptidase family (DUF2324)
BWEI_RS22700	COG0789	Transcriptional regulator
BWEI_RS22710	COG4470	Protein conserved in bacteria
BWEI_RS22730	COG1494	fructose-1,6-bisphosphatase
BWEI_RS22735	COG2445	Protein of unknown function DUF86
BWEI_RS22745	COG0647	UMP catabolic process
BWEI_RS22755	COG2249	NAD(P)H dehydrogenase (quinone) activity
BWEI_RS22775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BWEI_RS22780	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BWEI_RS22790	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BWEI_RS22795	COG4837	Protein of unknown function (DUF1462)
BWEI_RS22820	COG2824	Alkylphosphonate utilization operon protein PhnA
BWEI_RS22825	COG0390	transport system, permease component
BWEI_RS22835	COG1252	NADH dehydrogenase
BWEI_RS22840	COG4844	belongs to the
BWEI_RS22845	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BWEI_RS22850	COG0316	Belongs to the HesB IscA family
BWEI_RS22870	COG1683	Conserved Protein
BWEI_RS22885	COG3708	Transcriptional regulator
BWEI_RS22890	COG0492	ferredoxin-NADP+ reductase activity
BWEI_RS22895	COG1252	NADH dehydrogenase
BWEI_RS22910	COG3584	3D domain protein
BWEI_RS22915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BWEI_RS22925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWEI_RS22930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWEI_RS22935	COG1268	BioY protein
BWEI_RS22945	COG2050	protein possibly involved in aromatic compounds catabolism
BWEI_RS22965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BWEI_RS22970	COG5018	Exonuclease
BWEI_RS22985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BWEI_RS22995	COG2267	carboxylic ester hydrolase activity
BWEI_RS23000	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BWEI_RS23005	COG1522	sequence-specific DNA binding
BWEI_RS23010	COG0436	Aminotransferase
BWEI_RS23015	COG1098	S1 RNA binding domain
BWEI_RS23020	COG2155	Conserved Protein
BWEI_RS23025	COG0166	Belongs to the GPI family
BWEI_RS23035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BWEI_RS23040	COG1285	pathogenesis
BWEI_RS23045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BWEI_RS23055	COG0581	inorganic phosphate transmembrane transporter activity
BWEI_RS23060	COG0573	inorganic phosphate transmembrane transporter activity
BWEI_RS23065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BWEI_RS23075	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BWEI_RS23080	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BWEI_RS23090	COG0531	amino acid
BWEI_RS23095	COG0697	spore germination
BWEI_RS23100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BWEI_RS23115	COG4990	cell redox homeostasis
BWEI_RS23120	COG0833	amino acid
BWEI_RS23130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BWEI_RS23135	COG1845	cytochrome c oxidase, subunit III
BWEI_RS23145	COG0475	glutathione-regulated potassium exporter activity
BWEI_RS23145	COG0569	domain protein
BWEI_RS23155	COG2153	protein acetylation
BWEI_RS23170	COG2252	PERMEase
BWEI_RS23175	COG1113	amino acid transport
BWEI_RS23190	COG1114	Component of the transport system for branched-chain amino acids
BWEI_RS23195	COG3104	oligopeptide transport
BWEI_RS23215	COG1476	TRANSCRIPTIONal
BWEI_RS23220	COG3584	3D domain protein
BWEI_RS23220	COG3583	domain protein
BWEI_RS23225	COG0840	transmembrane signaling receptor activity
BWEI_RS23270	COG1063	alcohol dehydrogenase
BWEI_RS23300	COG1879	ABC-type sugar transport system periplasmic component
BWEI_RS23305	COG1172	Belongs to the binding-protein-dependent transport system permease family
BWEI_RS23315	COG1869	D-ribose catabolic process
BWEI_RS23320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BWEI_RS23325	COG1609	Transcriptional regulator
BWEI_RS23330	COG0477	Major facilitator Superfamily
BWEI_RS23335	COG1846	Transcriptional regulator
BWEI_RS23340	COG2271	Major facilitator Superfamily
BWEI_RS23350	COG4608	Belongs to the ABC transporter superfamily
BWEI_RS23355	COG0601	transmembrane transport
BWEI_RS23375	COG0659	secondary active sulfate transmembrane transporter activity
BWEI_RS23390	COG5002	protein histidine kinase activity
BWEI_RS23395	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BWEI_RS23400	COG2378	regulation of single-species biofilm formation
BWEI_RS23425	COG0833	amino acid
BWEI_RS23430	COG0765	amino acid transport
BWEI_RS23435	COG0765	amino acid transport
BWEI_RS23440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS23445	COG1126	abc transporter atp-binding protein
BWEI_RS23450	COG1115	amino acid carrier protein
BWEI_RS23455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BWEI_RS23470	COG1404	Belongs to the peptidase S8 family
BWEI_RS23475	COG2197	response regulator
BWEI_RS23480	COG4585	Histidine kinase
BWEI_RS23485	COG0697	spore germination
BWEI_RS23500	COG0366	Alpha amylase catalytic
BWEI_RS23505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS23505	COG1263	PTS System
BWEI_RS23510	COG2188	Transcriptional regulator
BWEI_RS23515	COG0531	amino acid
BWEI_RS23535	COG0714	Associated with various cellular activities
BWEI_RS23540	COG4548	von Willebrand factor, type A
BWEI_RS23550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWEI_RS23555	COG0156	8-amino-7-oxononanoate synthase activity
BWEI_RS23570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS23575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS23580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS23585	COG3104	oligopeptide transport
BWEI_RS23600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BWEI_RS23605	COG1620	l-lactate permease
BWEI_RS23610	COG1027	Aspartate ammonia-lyase
BWEI_RS23615	COG1253	flavin adenine dinucleotide binding
BWEI_RS23620	COG0346	lactoylglutathione lyase activity
BWEI_RS23625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS23630	COG1316	TRANSCRIPTIONal
BWEI_RS23635	COG2720	vancomycin resistance protein
BWEI_RS23655	COG3227	Zinc metalloprotease (Elastase)
BWEI_RS23665	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BWEI_RS23670	COG2217	Heavy metal translocating P-type atpase
BWEI_RS23675	COG0640	Transcriptional regulator
BWEI_RS23685	COG0531	amino acid
BWEI_RS23700	COG2427	Protein of unknown function (DUF1641)
BWEI_RS23705	COG3383	formate dehydrogenase (NAD+) activity
BWEI_RS23710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BWEI_RS23715	COG0456	acetyltransferase
BWEI_RS23720	COG0745	RESPONSE REGULATOR receiver
BWEI_RS23725	COG5002	protein histidine kinase activity
BWEI_RS23735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BWEI_RS23740	COG0697	spore germination
BWEI_RS23750	COG0281	malic enzyme
BWEI_RS23755	COG3493	citrate carrier protein
BWEI_RS23760	COG4565	transcriptional regulatory protein
BWEI_RS23765	COG3290	protein histidine kinase activity
BWEI_RS23775	COG4990	cell redox homeostasis
BWEI_RS23785	COG5002	protein histidine kinase activity
BWEI_RS23790	COG0745	RESPONSE REGULATOR receiver
BWEI_RS23795	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BWEI_RS23805	COG0395	ABC-type sugar transport system, permease component
BWEI_RS23810	COG1175	transmembrane transport
BWEI_RS23815	COG3842	ATPase activity
BWEI_RS23820	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BWEI_RS23845	COG2851	Citrate transporter
BWEI_RS23850	COG4565	transcriptional regulatory protein
BWEI_RS23855	COG3290	protein histidine kinase activity
BWEI_RS23865	COG2268	Band 7 protein
BWEI_RS23870	COG1585	Membrane protein implicated in regulation of membrane protease activity
BWEI_RS23885	COG2718	Belongs to the UPF0229 family
BWEI_RS23890	COG2766	serine protein kinase
BWEI_RS23895	COG3300	MHYT domain
BWEI_RS23895	COG5001	Diguanylate cyclase
BWEI_RS23900	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BWEI_RS23920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BWEI_RS23925	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BWEI_RS24125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BWEI_RS24130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BWEI_RS24135	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BWEI_RS24140	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BWEI_RS24145	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWEI_RS24150	COG0047	phosphoribosylformylglycinamidine synthase activity
BWEI_RS24155	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BWEI_RS24160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BWEI_RS24165	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BWEI_RS24170	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BWEI_RS24175	COG0138	bifunctional purine biosynthesis protein purh
BWEI_RS24180	COG0151	Belongs to the GarS family
BWEI_RS24200	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BWEI_RS24205	COG0210	DNA helicase
BWEI_RS24210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BWEI_RS24215	COG4851	CamS sex pheromone cAM373 precursor
BWEI_RS24225	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS24230	COG1335	isochorismatase
BWEI_RS24240	COG2011	ABC-type metal ion transport system permease component
BWEI_RS24245	COG1464	Belongs to the NlpA lipoprotein family
BWEI_RS24255	COG0003	Pfam Anion-transporting ATPase
BWEI_RS24260	COG1846	Transcriptional regulator
BWEI_RS24265	COG4682	membrane
BWEI_RS24275	COG0154	amidase activity
BWEI_RS24280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BWEI_RS24285	COG1597	lipid kinase activity
BWEI_RS24295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BWEI_RS24305	COG1012	belongs to the aldehyde dehydrogenase family
BWEI_RS24310	COG2076	Multidrug Resistance protein
BWEI_RS24315	COG2309	aminopeptidase activity
BWEI_RS24330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BWEI_RS24340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWEI_RS24345	COG5002	protein histidine kinase activity
BWEI_RS24350	COG4807	Protein conserved in bacteria
BWEI_RS24375	COG1757	Na H antiporter
BWEI_RS24380	COG1473	amidohydrolase
BWEI_RS24395	COG0450	alkyl hydroperoxide reductase
BWEI_RS24405	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BWEI_RS24415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS24420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BWEI_RS24425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BWEI_RS24430	COG0492	ferredoxin-NADP+ reductase activity
BWEI_RS24440	COG0166	Belongs to the GPI family
BWEI_RS24465	COG5002	protein histidine kinase activity
BWEI_RS24485	COG3541	Predicted nucleotidyltransferase
BWEI_RS24490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BWEI_RS24490	COG0723	plastoquinol--plastocyanin reductase activity
BWEI_RS24500	COG0765	amino acid transport
BWEI_RS24505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BWEI_RS24515	COG3290	protein histidine kinase activity
BWEI_RS24515	COG0840	transmembrane signaling receptor activity
BWEI_RS24540	COG0549	Belongs to the carbamate kinase family
BWEI_RS24555	COG0277	FAD linked oxidase domain protein
BWEI_RS24560	COG0366	Alpha amylase catalytic
BWEI_RS24565	COG1263	PTS System
BWEI_RS24565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS24565	COG2190	(PTS) system
BWEI_RS24585	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BWEI_RS24590	COG0352	thiamine-phosphate diphosphorylase activity
BWEI_RS24595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BWEI_RS24610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BWEI_RS24615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BWEI_RS24620	COG1116	anion transmembrane transporter activity
BWEI_RS24625	COG0488	(ABC) transporter
BWEI_RS24665	COG2270	Major facilitator Superfamily
BWEI_RS24695	COG2310	stress, protein
BWEI_RS24700	COG2310	stress, protein
BWEI_RS24705	COG2310	stress, protein
BWEI_RS24710	COG0861	Integral membrane protein TerC family
BWEI_RS24720	COG3853	Toxic anion resistance protein (TelA)
BWEI_RS24730	COG4840	Belongs to the UPF0435 family
BWEI_RS24745	COG1295	ribonuclease BN
BWEI_RS24750	COG2217	Heavy metal translocating P-type atpase
BWEI_RS24755	COG0697	spore germination
BWEI_RS24775	COG0586	Pfam SNARE associated Golgi protein
BWEI_RS24790	COG3871	stress protein (general stress protein 26)
BWEI_RS24795	COG0387	Pfam Sodium calcium exchanger
BWEI_RS24805	COG0535	radical SAM domain protein
BWEI_RS24825	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BWEI_RS24845	COG3829	transcription factor binding
BWEI_RS24855	COG0833	amino acid
BWEI_RS24860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BWEI_RS24880	COG2066	Belongs to the glutaminase family
BWEI_RS24885	COG1263	PTS System
BWEI_RS24885	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BWEI_RS24890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BWEI_RS24910	COG1216	Glycosyl transferase, family 2
BWEI_RS24920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BWEI_RS24920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWEI_RS24925	COG0463	Glycosyl transferase, family 2
BWEI_RS24940	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BWEI_RS24945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BWEI_RS24955	COG1228	amidohydrolase
BWEI_RS24960	COG1090	epimerase
BWEI_RS24965	COG2137	regulation of response to DNA damage stimulus
BWEI_RS24985	COG1988	membrane-bound metal-dependent
BWEI_RS24990	COG1194	a g-specific adenine glycosylase
BWEI_RS25005	COG3557	Belongs to the UPF0374 family
BWEI_RS25010	COG1132	(ABC) transporter
BWEI_RS25015	COG4129	membrane
BWEI_RS25020	COG0067	glutamate synthase
BWEI_RS25020	COG0069	glutamate synthase activity
BWEI_RS25020	COG0070	glutamate synthase
BWEI_RS25025	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BWEI_RS25030	COG4555	ABC transporter
BWEI_RS25050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BWEI_RS25055	COG0735	belongs to the Fur family
BWEI_RS25080	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BWEI_RS25090	COG0662	Cupin 2, conserved barrel domain protein
BWEI_RS25130	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS25160	COG4974	Belongs to the 'phage' integrase family
BWEI_RS25170	COG1309	transcriptional regulator
BWEI_RS25175	COG0791	NLP P60 protein
BWEI_RS25175	COG0741	lytic transglycosylase activity
BWEI_RS25185	COG2814	Major facilitator Superfamily
BWEI_RS25275	COG0745	RESPONSE REGULATOR receiver
BWEI_RS25280	COG1216	Glycosyl transferase, family 2
BWEI_RS25335	COG1309	transcriptional regulator
BWEI_RS25360	COG0083	homoserine kinase activity
BWEI_RS25525	COG4326	sporulation control protein
BWEI_RS25545	COG2070	2-Nitropropane dioxygenase
BWEI_RS25580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWEI_RS25595	COG1482	cell wall glycoprotein biosynthetic process
BWEI_RS25600	COG0662	Cupin 2, conserved barrel domain protein
BWEI_RS25600	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BWEI_RS25605	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BWEI_RS25615	COG0110	maltose O-acetyltransferase activity
BWEI_RS25645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BWEI_RS25650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWEI_RS25655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BWEI_RS25660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BWEI_RS25665	COG4464	protein tyrosine phosphatase activity
BWEI_RS25670	COG0489	protein tyrosine kinase activity
BWEI_RS25675	COG3944	biosynthesis protein
BWEI_RS25750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BWEI_RS25785	COG0659	secondary active sulfate transmembrane transporter activity
BWEI_RS25800	COG2824	Alkylphosphonate utilization operon protein PhnA
BWEI_RS25895	COG2183	response to ionizing radiation
BWEI_RS25900	COG2337	Toxic component of a toxin-antitoxin (TA) module
BWEI_RS25905	COG0864	Transcriptional regulator
BWEI_RS25915	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BWEI_RS25920	COG0736	holo-[acyl-carrier-protein] synthase activity
BWEI_RS25930	COG4294	response to UV
BWEI_RS25940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BWEI_RS25950	COG2814	Major facilitator Superfamily
BWEI_RS25960	COG0179	Fumarylacetoacetate (FAA) hydrolase
BWEI_RS25965	COG3185	4-Hydroxyphenylpyruvate dioxygenase
BWEI_RS25980	COG0561	phosphatase activity
BWEI_RS25985	COG4608	Belongs to the ABC transporter superfamily
BWEI_RS25990	COG0444	Belongs to the ABC transporter superfamily
BWEI_RS25995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWEI_RS26000	COG0601	transmembrane transport
BWEI_RS26020	COG0842	Transport permease protein
BWEI_RS26025	COG1511	domain protein
BWEI_RS26025	COG0842	Transport permease protein
BWEI_RS26030	COG1131	(ABC) transporter
BWEI_RS26035	COG2197	response regulator
BWEI_RS26040	COG4585	Histidine kinase
BWEI_RS26045	COG0488	(ABC) transporter
BWEI_RS26065	COG5298	Protein conserved in bacteria
BWEI_RS26085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BWEI_RS26095	COG1609	Transcriptional regulator
BWEI_RS26100	COG0204	Acyl-transferase
BWEI_RS26105	COG0697	spore germination
BWEI_RS26115	COG1910	domain protein
BWEI_RS26120	COG0725	ABC transporter, periplasmic molybdate-binding protein
BWEI_RS26125	COG4149	molybdate abc transporter
BWEI_RS26140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BWEI_RS26145	COG0656	L-ascorbic acid biosynthetic process
BWEI_RS26150	COG4166	transmembrane transport
BWEI_RS26155	COG4166	transmembrane transport
BWEI_RS26165	COG4166	transmembrane transport
BWEI_RS26170	COG4608	Belongs to the ABC transporter superfamily
BWEI_RS26175	COG0444	Belongs to the ABC transporter superfamily
BWEI_RS26180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BWEI_RS26185	COG0601	transmembrane transport
BWEI_RS26200	COG2814	Major facilitator Superfamily
BWEI_RS26210	COG2271	Major facilitator Superfamily
BWEI_RS26215	COG0277	FAD linked oxidase domain protein
BWEI_RS26225	COG0604	alcohol dehydrogenase
BWEI_RS26230	COG1464	Belongs to the NlpA lipoprotein family
BWEI_RS26240	COG2011	ABC-type metal ion transport system permease component
BWEI_RS26245	COG1028	Short-chain dehydrogenase reductase Sdr
BWEI_RS26270	COG4946	Tricorn protease homolog
BWEI_RS26270	COG0823	Involved in the tonB-independent uptake of proteins
BWEI_RS26270	COG1506	peptidase
BWEI_RS26285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BWEI_RS26290	COG4856	YbbR-like protein
BWEI_RS26295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BWEI_RS26345	COG3880	PFAM UvrB UvrC protein
BWEI_RS26350	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BWEI_RS26355	COG0542	response to heat
BWEI_RS26360	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BWEI_RS26365	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BWEI_RS26370	COG4956	integral membrane protein (PIN domain superfamily)
BWEI_RS26375	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BWEI_RS26385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BWEI_RS26390	COG1045	serine acetyltransferase
BWEI_RS26395	COG0215	cysteine-tRNA ligase activity
BWEI_RS26405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BWEI_RS26410	COG3688	RNA-binding protein containing a PIN domain
BWEI_RS26420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BWEI_RS26425	COG0250	Participates in transcription elongation, termination and antitermination
BWEI_RS26430	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BWEI_RS26435	COG0081	regulation of translation
BWEI_RS26440	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BWEI_RS26445	COG0222	ribosome binding
BWEI_RS26450	COG2813	Specifically methylates the guanine in position
BWEI_RS26455	COG0085	RNA polymerase activity
BWEI_RS26460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BWEI_RS26465	COG1358	cellular component organization or biogenesis
BWEI_RS26470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BWEI_RS26480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BWEI_RS26485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BWEI_RS26490	COG0051	transcription antitermination factor activity, RNA binding
BWEI_RS26495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BWEI_RS26500	COG0088	Forms part of the polypeptide exit tunnel
BWEI_RS26505	COG0089	rRNA binding
BWEI_RS26510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BWEI_RS26515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BWEI_RS26520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BWEI_RS26535	COG0255	Belongs to the universal ribosomal protein uL29 family
BWEI_RS26540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BWEI_RS26550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BWEI_RS26555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BWEI_RS26565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BWEI_RS26575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BWEI_RS26585	COG1841	ribosomal large subunit assembly
BWEI_RS26590	COG0200	Binds to the 23S rRNA
BWEI_RS26595	COG0201	protein transport
BWEI_RS26600	COG0563	adenylate kinase activity
BWEI_RS26605	COG0024	Methionine aminopeptidase
BWEI_RS26615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BWEI_RS26620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BWEI_RS26625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BWEI_RS26650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BWEI_RS26660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BWEI_RS26665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BWEI_RS26675	COG0860	N-Acetylmuramoyl-L-alanine amidase
BWEI_RS26680	COG0489	protein tyrosine kinase activity
BWEI_RS26690	COG2194	sulfuric ester hydrolase activity
BWEI_RS26695	COG0726	polysaccharide deacetylase
BWEI_RS26710	COG1982	Orn Lys Arg decarboxylase major
BWEI_RS26715	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BWEI_RS26720	COG0470	DNA polymerase III
BWEI_RS26725	COG1774	PSP1 C-terminal conserved region
BWEI_RS26730	COG4467	Involved in initiation control of chromosome replication
BWEI_RS26735	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BWEI_RS26745	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BWEI_RS26750	COG2002	toxin-antitoxin pair type II binding
BWEI_RS26760	COG0084	hydrolase, TatD family'
BWEI_RS26770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BWEI_RS26780	COG4466	Protein conserved in bacteria
BWEI_RS26790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BWEI_RS26795	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BWEI_RS26800	COG0251	oxidation-reduction process
BWEI_RS26805	COG2088	sporulation resulting in formation of a cellular spore
BWEI_RS26810	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BWEI_RS26830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BWEI_RS26835	COG2002	toxin-antitoxin pair type II binding
BWEI_RS26840	COG2244	polysaccharide biosynthetic process
BWEI_RS26845	COG3956	TIGRFAM MazG family protein
BWEI_RS26850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BWEI_RS26870	COG1098	S1 RNA binding domain
BWEI_RS26885	COG2208	phosphoserine phosphatase activity
BWEI_RS26895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BWEI_RS26900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BWEI_RS26905	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BWEI_RS26910	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BWEI_RS26915	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BWEI_RS26920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BWEI_RS26925	COG0512	Glutamine amidotransferase of anthranilate synthase
BWEI_RS26930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BWEI_RS26935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BWEI_RS26940	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BWEI_RS26945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BWEI_RS26950	COG1396	sequence-specific DNA binding
BWEI_RS26955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BWEI_RS26960	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BWEI_RS27055	COG1674	ftsk spoiiie
BWEI_RS27170	COG0463	Glycosyl transferase, family 2
BWEI_RS27215	COG1923	regulation of RNA biosynthetic process
BWEI_RS27220	COG0582	viral genome integration into host DNA
BWEI_RS27255	COG2732	(Barnase) inhibitor
BWEI_RS27275	COG0210	DNA helicase
BWEI_RS27310	COG2223	nitrite transmembrane transporter activity
BWEI_RS27340	COG3764	Sortase (surface protein transpeptidase)
BWEI_RS27360	COG2002	toxin-antitoxin pair type II binding
BWEI_RS27380	COG0802	atpase or kinase
BWEI_RS27385	COG1214	PFAM Peptidase M22, glycoprotease
BWEI_RS27390	COG0456	acetyltransferase
BWEI_RS27400	COG0488	(ABC) transporter
BWEI_RS27405	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BWEI_RS27415	COG1266	CAAX protease self-immunity
BWEI_RS27420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BWEI_RS27425	COG0459	protein refolding
BWEI_RS27430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BWEI_RS27430	COG0519	Catalyzes the synthesis of GMP from XMP
BWEI_RS27435	COG2252	PERMEase
BWEI_RS27445	COG5002	protein histidine kinase activity
BWEI_RS27455	COG0517	IMP dehydrogenase activity
BWEI_RS27455	COG0516	GMP reductase activity
BWEI_RS27460	COG1686	Belongs to the peptidase S11 family
BWEI_RS27465	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BWEI_RS27470	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BWEI_RS27490	COG1428	Deoxynucleoside kinase
BWEI_RS27495	COG1428	Deoxynucleoside kinase
BWEI_RS27500	COG1335	isochorismatase
BWEI_RS27505	COG0590	tRNA wobble adenosine to inosine editing
BWEI_RS27510	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BWEI_RS27515	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BWEI_RS27520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BWEI_RS27590	COG0582	viral genome integration into host DNA
BWEI_RS27605	COG2226	methyltransferase
BWEI_RS27615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BWEI_RS27625	COG1215	transferase activity, transferring glycosyl groups
BWEI_RS27630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BWEI_RS27635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BWEI_RS27645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BWEI_RS27690	COG0697	spore germination
BWEI_RS27775	COG1216	Glycosyl transferase, family 2
BWEI_RS27815	COG2076	Multidrug Resistance protein
BWEI_RS27850	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BWEI_RS27850	COG1605	Chorismate mutase
BWEI_RS27855	COG1605	Chorismate mutase
BWEI_RS27855	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BWEI_RS28015	COG3093	addiction module antidote protein HigA
BWEI_RS28385	COG3284	Transcriptional regulator
BWEI_RS28865	COG2376	Dihydroxyacetone kinase
BWEI_RS29270	COG0705	Rhomboid family
BWEI_RS29300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BWEI_RS29320	COG4589	Belongs to the CDS family