locus-tag	class	description
FPL01_RS00010	COG1136	(ABC) transporter
FPL01_RS00165	COG0582	viral genome integration into host DNA
FPL01_RS00175	COG1192	Involved in chromosome partitioning
FPL01_RS00240	COG2732	(Barnase) inhibitor
FPL01_RS00295	COG3344	reverse transcriptase
FPL01_RS00340	COG2311	Membrane
FPL01_RS00385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPL01_RS00415	COG2002	toxin-antitoxin pair type II binding
FPL01_RS00425	COG4974	Belongs to the 'phage' integrase family
FPL01_RS00500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPL01_RS00515	COG3271	cysteine-type peptidase activity
FPL01_RS00515	COG2274	protein secretion by the type I secretion system
FPL01_RS00520	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS00525	COG0463	Glycosyl transferase, family 2
FPL01_RS00530	COG0463	Glycosyl transferase, family 2
FPL01_RS00535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FPL01_RS00550	COG2207	Transcriptional regulator
FPL01_RS00550	COG3708	Transcriptional regulator
FPL01_RS00575	COG0537	adenosine 5'-monophosphoramidase activity
FPL01_RS00625	COG3655	Transcriptional regulator
FPL01_RS00640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPL01_RS00670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL01_RS00685	COG2323	membrane
FPL01_RS00725	COG1733	regulation of RNA biosynthetic process
FPL01_RS00735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FPL01_RS00745	COG2918	glutathione biosynthetic process
FPL01_RS00745	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPL01_RS00770	COG1335	isochorismatase
FPL01_RS00775	COG4990	cell redox homeostasis
FPL01_RS00780	COG0745	RESPONSE REGULATOR receiver
FPL01_RS00785	COG5002	protein histidine kinase activity
FPL01_RS00810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPL01_RS00815	COG1621	beta-fructofuranosidase activity
FPL01_RS00820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL01_RS00820	COG1263	PTS System
FPL01_RS00825	COG1609	Transcriptional regulator
FPL01_RS00875	COG0457	Tetratricopeptide repeat
FPL01_RS01015	COG3344	reverse transcriptase
FPL01_RS01020	COG3344	reverse transcriptase
FPL01_RS01050	COG3397	chitin binding
FPL01_RS01065	COG0840	transmembrane signaling receptor activity
FPL01_RS01065	COG5278	phosphoserine phosphatase activity
FPL01_RS01090	COG0791	NLP P60 protein
FPL01_RS01090	COG1388	LysM domain
FPL01_RS01090	COG3103	Sh3 type 3 domain protein
FPL01_RS01115	COG0640	Transcriptional regulator
FPL01_RS01185	COG1404	Belongs to the peptidase S8 family
FPL01_RS01325	COG3344	reverse transcriptase
FPL01_RS01425	COG4962	Type ii secretion system protein e
FPL01_RS01515	COG0528	UMP kinase activity
FPL01_RS01525	COG1027	Aspartate ammonia-lyase
FPL01_RS01530	COG0281	malic enzyme
FPL01_RS01535	COG4191	Histidine kinase
FPL01_RS01540	COG0784	Response regulator, receiver
FPL01_RS01545	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPL01_RS01560	COG3620	sequence-specific DNA binding
FPL01_RS01590	COG1051	belongs to the nudix hydrolase family
FPL01_RS01595	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS01605	COG2814	Major facilitator Superfamily
FPL01_RS01620	COG3842	ATPase activity
FPL01_RS01625	COG2508	Transcriptional regulator
FPL01_RS01635	COG1175	transmembrane transport
FPL01_RS01640	COG0395	ABC-type sugar transport system, permease component
FPL01_RS01650	COG2188	Transcriptional regulator
FPL01_RS01655	COG2222	sugar isomerase
FPL01_RS01670	COG1105	Belongs to the carbohydrate kinase PfkB family
FPL01_RS01675	COG1940	carbohydrate kinase activity
FPL01_RS01685	COG1695	Transcriptional regulator
FPL01_RS01695	COG0477	Major facilitator Superfamily
FPL01_RS01700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL01_RS01715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPL01_RS01720	COG4166	transmembrane transport
FPL01_RS01725	COG2223	nitrite transmembrane transporter activity
FPL01_RS01730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPL01_RS01745	COG2244	polysaccharide biosynthetic process
FPL01_RS01750	COG0733	neurotransmitter:sodium symporter activity
FPL01_RS01760	COG5566	PFAM Mor transcription activator
FPL01_RS01765	COG2323	membrane
FPL01_RS01785	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL01_RS01800	COG0028	Belongs to the TPP enzyme family
FPL01_RS01820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FPL01_RS01845	COG2814	Major facilitator Superfamily
FPL01_RS01850	COG3384	dioxygenase
FPL01_RS01870	COG3279	Response regulator of the LytR AlgR family
FPL01_RS01875	COG0427	acetyl-CoA hydrolase
FPL01_RS01900	COG4166	transmembrane transport
FPL01_RS01905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS01945	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPL01_RS01950	COG0531	amino acid
FPL01_RS01970	COG1280	lysine exporter protein (LysE YggA)
FPL01_RS01980	COG1266	CAAX protease self-immunity
FPL01_RS01985	COG1309	transcriptional regulator
FPL01_RS01990	COG2390	Transcriptional regulator
FPL01_RS02000	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS02005	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FPL01_RS02020	COG4846	Membrane protein involved in cytochrome C biogenesis
FPL01_RS02030	COG0006	proline dipeptidase activity
FPL01_RS02070	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS02080	COG1276	copper resistance
FPL01_RS02080	COG2372	response to copper ion
FPL01_RS02085	COG4549	nuclear export factor GLE1
FPL01_RS02090	COG0697	spore germination
FPL01_RS02095	COG0583	DNA-binding transcription factor activity
FPL01_RS02100	COG1959	2 iron, 2 sulfur cluster binding
FPL01_RS02105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPL01_RS02110	COG0778	Nitroreductase
FPL01_RS02120	COG0628	permease
FPL01_RS02130	COG1231	oxidoreductase activity
FPL01_RS02135	COG0523	cobalamin synthesis protein
FPL01_RS02145	COG0411	ABC transporter
FPL01_RS02175	COG1942	4-Oxalocrotonate Tautomerase
FPL01_RS02195	COG1271	oxidase subunit
FPL01_RS02200	COG1294	oxidase, subunit
FPL01_RS02205	COG4988	ABC transporter
FPL01_RS02210	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FPL01_RS02255	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPL01_RS02260	COG1686	Belongs to the peptidase S11 family
FPL01_RS02275	COG1388	LysM domain
FPL01_RS02275	COG0791	NLP P60 protein
FPL01_RS02285	COG1132	(ABC) transporter
FPL01_RS02295	COG5002	protein histidine kinase activity
FPL01_RS02310	COG0300	oxidoreductase activity
FPL01_RS02315	COG4122	O-methyltransferase activity
FPL01_RS02345	COG0460	homoserine dehydrogenase
FPL01_RS02370	COG1316	TRANSCRIPTIONal
FPL01_RS02390	COG1285	pathogenesis
FPL01_RS02405	COG2814	Major facilitator Superfamily
FPL01_RS02410	COG1279	arginine transmembrane transporter activity
FPL01_RS02415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS02465	COG2002	toxin-antitoxin pair type II binding
FPL01_RS02470	COG1404	Belongs to the peptidase S8 family
FPL01_RS02475	COG0640	Transcriptional regulator
FPL01_RS02480	COG0667	Aldo Keto reductase
FPL01_RS02485	COG2814	Major facilitator Superfamily
FPL01_RS02490	COG3152	Membrane
FPL01_RS02515	COG0840	transmembrane signaling receptor activity
FPL01_RS02530	COG3949	Membrane
FPL01_RS02535	COG3949	Membrane
FPL01_RS02540	COG0783	Belongs to the Dps family
FPL01_RS02560	COG1231	oxidoreductase activity
FPL01_RS02565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS02570	COG4989	oxidoreductase activity
FPL01_RS02575	COG0523	cobalamin synthesis protein
FPL01_RS02580	COG0456	acetyltransferase
FPL01_RS02595	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPL01_RS02595	COG3443	Belongs to the bacterial solute-binding protein 9 family
FPL01_RS02600	COG0702	epimerase
FPL01_RS02610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPL01_RS02620	COG4166	transmembrane transport
FPL01_RS02650	COG1051	belongs to the nudix hydrolase family
FPL01_RS02655	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS02660	COG2244	polysaccharide biosynthetic process
FPL01_RS02675	COG3689	TIGRFAM TIGR03943 family protein
FPL01_RS02680	COG1607	acyl-coa hydrolase
FPL01_RS02690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPL01_RS02705	COG0702	epimerase
FPL01_RS02715	COG1253	flavin adenine dinucleotide binding
FPL01_RS02735	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS02740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL01_RS02760	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS02770	COG1876	peptidase activity
FPL01_RS02780	COG0154	amidase activity
FPL01_RS02785	COG2211	Major facilitator Superfamily
FPL01_RS02800	COG2368	4-hydroxyphenylacetate
FPL01_RS02810	COG0196	riboflavin kinase activity
FPL01_RS02825	COG0251	oxidation-reduction process
FPL01_RS02835	COG3971	2-oxopent-4-enoate hydratase activity
FPL01_RS02855	COG1942	4-Oxalocrotonate Tautomerase
FPL01_RS02865	COG0561	phosphatase activity
FPL01_RS02875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPL01_RS02880	COG4106	trans-aconitate 2-methyltransferase activity
FPL01_RS02895	COG1819	glycosyl
FPL01_RS02900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS02905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS02935	COG0456	acetyltransferase
FPL01_RS02960	COG3874	Sporulation protein YtfJ
FPL01_RS02985	COG2226	methyltransferase
FPL01_RS03005	COG1082	Xylose isomerase domain protein TIM barrel
FPL01_RS03010	COG0346	lactoylglutathione lyase activity
FPL01_RS03020	COG0604	alcohol dehydrogenase
FPL01_RS03025	COG1595	DNA-templated transcription, initiation
FPL01_RS03055	COG0386	Belongs to the glutathione peroxidase family
FPL01_RS03060	COG1305	Transglutaminase-like
FPL01_RS03070	COG0714	Associated with various cellular activities
FPL01_RS03105	COG2359	stage V sporulation protein S
FPL01_RS03115	COG1418	mRNA catabolic process
FPL01_RS03135	COG0629	single-stranded DNA binding
FPL01_RS03150	COG1413	lyase activity
FPL01_RS03165	COG2136	Putative SAM-dependent methyltransferase
FPL01_RS03165	COG2521	methyltransferase
FPL01_RS03170	COG0018	arginyl-trna synthetase
FPL01_RS03210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPL01_RS03215	COG0017	Asparaginyl-tRNA synthetase
FPL01_RS03235	COG1674	ftsk spoiiie
FPL01_RS03290	COG0733	neurotransmitter:sodium symporter activity
FPL01_RS03315	COG2610	gluconate transmembrane transporter activity
FPL01_RS03320	COG1454	alcohol dehydrogenase
FPL01_RS03325	COG1794	racemase activity, acting on amino acids and derivatives
FPL01_RS03335	COG0456	acetyltransferase
FPL01_RS03340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FPL01_RS03350	COG1131	(ABC) transporter
FPL01_RS03365	COG0546	phosphoglycolate phosphatase activity
FPL01_RS03380	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPL01_RS03385	COG3250	beta-galactosidase activity
FPL01_RS03400	COG0768	penicillin binding
FPL01_RS03410	COG0204	Acyl-transferase
FPL01_RS03415	COG1272	protein, Hemolysin III
FPL01_RS03425	COG0805	protein transport
FPL01_RS03435	COG1307	EDD domain protein, DegV family
FPL01_RS03440	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPL01_RS03445	COG1999	signal sequence binding
FPL01_RS03450	COG0071	Belongs to the small heat shock protein (HSP20) family
FPL01_RS03455	COG0367	asparagine synthase
FPL01_RS03475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPL01_RS03495	COG1051	belongs to the nudix hydrolase family
FPL01_RS03500	COG0071	Belongs to the small heat shock protein (HSP20) family
FPL01_RS03505	COG0668	transmembrane transport
FPL01_RS03510	COG2203	Gaf domain
FPL01_RS03510	COG4585	Histidine kinase
FPL01_RS03515	COG2197	response regulator
FPL01_RS03530	COG1064	alcohol dehydrogenase
FPL01_RS03555	COG1070	Carbohydrate kinase
FPL01_RS03565	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPL01_RS03600	COG1125	glycine betaine transport
FPL01_RS03600	COG0517	IMP dehydrogenase activity
FPL01_RS03605	COG1174	glycine betaine transport
FPL01_RS03640	COG1253	flavin adenine dinucleotide binding
FPL01_RS03645	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS03650	COG5506	Protein of unknown function (DUF1694)
FPL01_RS03665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPL01_RS03670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FPL01_RS03675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FPL01_RS03680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL01_RS03685	COG0456	acetyltransferase
FPL01_RS03690	COG3829	transcription factor binding
FPL01_RS03695	COG1509	lysine 2,3-aminomutase activity
FPL01_RS03740	COG0671	phosphoesterase, PA-phosphatase related
FPL01_RS03745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPL01_RS03750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS03815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPL01_RS03875	COG0372	Belongs to the citrate synthase family
FPL01_RS03880	COG2079	MmgE PrpD family protein
FPL01_RS03885	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FPL01_RS03895	COG2084	Dehydrogenase
FPL01_RS03905	COG1280	lysine exporter protein (LysE YggA)
FPL01_RS03910	COG1024	Enoyl-CoA hydratase
FPL01_RS03925	COG0420	3'-5' exonuclease activity
FPL01_RS03945	COG2223	nitrite transmembrane transporter activity
FPL01_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS03955	COG1169	isochorismate synthase
FPL01_RS03960	COG1021	2,3-dihydroxybenzoate-AMP ligase
FPL01_RS03965	COG3433	isochorismatase activity
FPL01_RS03965	COG1535	isochorismatase
FPL01_RS03975	COG3251	PFAM MbtH domain protein
FPL01_RS03980	COG2814	Major facilitator Superfamily
FPL01_RS03995	COG0776	regulation of translation
FPL01_RS04005	COG2318	DinB family
FPL01_RS04015	COG1115	amino acid carrier protein
FPL01_RS04040	COG2329	Antibiotic biosynthesis monooxygenase
FPL01_RS04045	COG1187	pseudouridine synthase activity
FPL01_RS04050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPL01_RS04055	COG1136	(ABC) transporter
FPL01_RS04065	COG0596	Alpha beta hydrolase
FPL01_RS04070	COG2814	Major facilitator Superfamily
FPL01_RS04095	COG2226	methyltransferase
FPL01_RS04140	COG1846	Transcriptional regulator
FPL01_RS04190	COG1247	-acetyltransferase
FPL01_RS04215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS04225	COG1278	Cold shock
FPL01_RS04240	COG0010	Belongs to the arginase family
FPL01_RS04250	COG0583	DNA-binding transcription factor activity
FPL01_RS04255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPL01_RS04285	COG1132	(ABC) transporter
FPL01_RS04315	COG1396	sequence-specific DNA binding
FPL01_RS04370	COG1649	PFAM Uncharacterised BCR, COG1649
FPL01_RS04395	COG2971	BadF BadG BcrA BcrD
FPL01_RS04415	COG1846	Transcriptional regulator
FPL01_RS04450	COG1309	transcriptional regulator
FPL01_RS04465	COG0577	efflux transmembrane transporter activity
FPL01_RS04465	COG1136	(ABC) transporter
FPL01_RS04470	COG3615	Tellurite resistance protein tehB
FPL01_RS04470	COG0500	methyltransferase
FPL01_RS04480	COG2226	methyltransferase
FPL01_RS04485	COG3961	Belongs to the TPP enzyme family
FPL01_RS04490	COG1846	Transcriptional regulator
FPL01_RS04535	COG0768	penicillin binding
FPL01_RS04540	COG1595	DNA-templated transcription, initiation
FPL01_RS04560	COG2367	Beta-lactamase
FPL01_RS04565	COG1408	metallophosphoesterase
FPL01_RS04575	COG1131	(ABC) transporter
FPL01_RS04585	COG1309	transcriptional regulator
FPL01_RS04600	COG1960	acyl-CoA dehydrogenase activity
FPL01_RS04605	COG0439	Biotin carboxylase
FPL01_RS04610	COG0511	ligase activity, forming carbon-carbon bonds
FPL01_RS04620	COG1024	Enoyl-CoA hydratase
FPL01_RS04625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPL01_RS04630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPL01_RS04640	COG0640	Transcriptional regulator
FPL01_RS04650	COG1247	-acetyltransferase
FPL01_RS04660	COG2318	DinB family
FPL01_RS04665	COG1686	Belongs to the peptidase S11 family
FPL01_RS04695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPL01_RS04715	COG3227	Zinc metalloprotease (Elastase)
FPL01_RS04720	COG2207	Transcriptional regulator
FPL01_RS04770	COG2814	Major facilitator Superfamily
FPL01_RS04780	COG2226	methyltransferase
FPL01_RS04815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS04825	COG2368	4-hydroxyphenylacetate
FPL01_RS04845	COG2323	membrane
FPL01_RS04850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FPL01_RS04855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPL01_RS04865	COG3386	PFAM SMP-30 Gluconolaconase
FPL01_RS04880	COG3773	Cell wall hydrolase
FPL01_RS04890	COG0745	RESPONSE REGULATOR receiver
FPL01_RS04895	COG2205	protein histidine kinase activity
FPL01_RS04910	COG1136	(ABC) transporter
FPL01_RS04945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS04955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FPL01_RS05060	COG2124	cytochrome p450
FPL01_RS05095	COG0561	phosphatase activity
FPL01_RS05105	COG5002	protein histidine kinase activity
FPL01_RS05115	COG1819	glycosyl
FPL01_RS05120	COG1794	racemase activity, acting on amino acids and derivatives
FPL01_RS05145	COG2205	protein histidine kinase activity
FPL01_RS05155	COG0456	acetyltransferase
FPL01_RS05155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPL01_RS05165	COG0745	RESPONSE REGULATOR receiver
FPL01_RS05170	COG5002	protein histidine kinase activity
FPL01_RS05175	COG0604	alcohol dehydrogenase
FPL01_RS05180	COG0671	phosphoesterase, PA-phosphatase related
FPL01_RS05260	COG0596	Alpha beta hydrolase
FPL01_RS05275	COG2814	Major facilitator Superfamily
FPL01_RS05290	COG0584	glycerophosphoryl diester phosphodiesterase
FPL01_RS05310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS05345	COG2223	nitrite transmembrane transporter activity
FPL01_RS05350	COG2816	NAD+ diphosphatase activity
FPL01_RS05355	COG0592	DNA-directed DNA polymerase activity
FPL01_RS05360	COG1051	belongs to the nudix hydrolase family
FPL01_RS05380	COG3878	Protein conserved in bacteria
FPL01_RS05400	COG4667	esterase of the alpha-beta hydrolase superfamily
FPL01_RS05440	COG0322	excinuclease ABC activity
FPL01_RS05475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPL01_RS05495	COG1011	Hydrolase
FPL01_RS05515	COG3227	Zinc metalloprotease (Elastase)
FPL01_RS05525	COG0346	lactoylglutathione lyase activity
FPL01_RS05530	COG0201	protein transport
FPL01_RS05535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPL01_RS05545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS05600	COG2959	enzyme of heme biosynthesis
FPL01_RS05680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS05700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPL01_RS05705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPL01_RS05710	COG0022	dehydrogenase e1 component
FPL01_RS05715	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPL01_RS05725	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS05730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPL01_RS05730	COG0456	acetyltransferase
FPL01_RS05745	COG0494	nUDIX hydrolase
FPL01_RS05770	COG4176	ABC-type proline glycine betaine transport system permease component
FPL01_RS05805	COG2153	protein acetylation
FPL01_RS05835	COG2205	protein histidine kinase activity
FPL01_RS05840	COG2226	methyltransferase
FPL01_RS05845	COG2315	Protein conserved in bacteria
FPL01_RS05855	COG0658	competence protein
FPL01_RS05855	COG2333	competence protein COMEC
FPL01_RS05915	COG2105	PFAM AIG2 family protein
FPL01_RS05920	COG0514	ATP-dependent DNA helicase (RecQ)
FPL01_RS05955	COG4637	Psort location Cytoplasmic, score
FPL01_RS05980	COG3397	chitin binding
FPL01_RS05995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FPL01_RS06000	COG1115	amino acid carrier protein
FPL01_RS06005	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS06010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPL01_RS06020	COG3938	Belongs to the proline racemase family
FPL01_RS06025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPL01_RS06065	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS06080	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FPL01_RS06085	COG0519	Catalyzes the synthesis of GMP from XMP
FPL01_RS06090	COG4166	transmembrane transport
FPL01_RS06100	COG4948	Mandelate Racemase Muconate Lactonizing
FPL01_RS06155	COG5002	protein histidine kinase activity
FPL01_RS06190	COG1164	Oligoendopeptidase f
FPL01_RS06200	COG1522	sequence-specific DNA binding
FPL01_RS06205	COG1307	EDD domain protein, DegV family
FPL01_RS06225	COG2814	Major facilitator Superfamily
FPL01_RS06235	COG1664	Polymer-forming cytoskeletal
FPL01_RS06240	COG0789	Transcriptional regulator
FPL01_RS06250	COG2814	Major facilitator Superfamily
FPL01_RS06250	COG0477	Major facilitator Superfamily
FPL01_RS06275	COG2261	transglycosylase associated protein
FPL01_RS06325	COG0436	Aminotransferase
FPL01_RS06330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPL01_RS06340	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FPL01_RS06355	COG1131	(ABC) transporter
FPL01_RS06405	COG0628	permease
FPL01_RS06415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPL01_RS06420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPL01_RS06425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPL01_RS06470	COG2746	aminoglycoside 3-N-acetyltransferase activity
FPL01_RS06490	COG0697	spore germination
FPL01_RS06495	COG2318	DinB family
FPL01_RS06530	COG0861	Integral membrane protein TerC family
FPL01_RS06535	COG1368	sulfuric ester hydrolase activity
FPL01_RS06540	COG0488	(ABC) transporter
FPL01_RS06550	COG1033	growth of symbiont in host cell
FPL01_RS06550	COG2409	Drug exporters of the RND superfamily
FPL01_RS06555	COG1309	transcriptional regulator
FPL01_RS06570	COG0287	Prephenate dehydrogenase
FPL01_RS06585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FPL01_RS06585	COG1605	Chorismate mutase
FPL01_RS06640	COG1309	transcriptional regulator
FPL01_RS06655	COG1879	ABC-type sugar transport system periplasmic component
FPL01_RS06660	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPL01_RS06665	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPL01_RS06675	COG2390	Transcriptional regulator
FPL01_RS06715	COG2329	Antibiotic biosynthesis monooxygenase
FPL01_RS06730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS06745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPL01_RS06750	COG4187	Peptidase family M20/M25/M40
FPL01_RS06755	COG1414	Transcriptional regulator
FPL01_RS06760	COG0833	amino acid
FPL01_RS06765	COG1690	Belongs to the RtcB family
FPL01_RS06770	COG3239	Fatty acid desaturase
FPL01_RS06800	COG3655	Transcriptional regulator
FPL01_RS06810	COG4377	Putative membrane peptidase family (DUF2324)
FPL01_RS06820	COG3279	Response regulator of the LytR AlgR family
FPL01_RS06845	COG0346	lactoylglutathione lyase activity
FPL01_RS06870	COG0714	Associated with various cellular activities
FPL01_RS06930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPL01_RS06935	COG0753	catalase activity
FPL01_RS06940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPL01_RS06960	COG1846	Transcriptional regulator
FPL01_RS06990	COG0714	Associated with various cellular activities
FPL01_RS07000	COG0778	Nitroreductase
FPL01_RS07005	COG1846	Transcriptional regulator
FPL01_RS07040	COG1136	(ABC) transporter
FPL01_RS07040	COG0577	efflux transmembrane transporter activity
FPL01_RS07065	COG2207	Transcriptional regulator
FPL01_RS07070	COG0456	acetyltransferase
FPL01_RS07130	COG0730	response to heat
FPL01_RS07140	COG0833	amino acid
FPL01_RS07160	COG0384	phenazine biosynthesis protein PhzF
FPL01_RS07220	COG1984	allophanate hydrolase subunit 2
FPL01_RS07225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FPL01_RS07240	COG3142	Participates in the control of copper homeostasis
FPL01_RS07245	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS07250	COG1960	acyl-CoA dehydrogenase activity
FPL01_RS07285	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FPL01_RS07300	COG3848	Pyruvate phosphate dikinase
FPL01_RS07300	COG0574	Belongs to the PEP-utilizing enzyme family
FPL01_RS07310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS07330	COG1063	alcohol dehydrogenase
FPL01_RS07340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FPL01_RS07355	COG0737	Belongs to the 5'-nucleotidase family
FPL01_RS07365	COG0598	Magnesium transport protein CorA
FPL01_RS07415	COG0415	Belongs to the DNA photolyase family
FPL01_RS07440	COG0657	acetylesterase activity
FPL01_RS07445	COG0288	reversible hydration of carbon dioxide
FPL01_RS07455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPL01_RS07460	COG5609	conserved protein (DUF2294)
FPL01_RS07475	COG1575	Belongs to the MenA family. Type 1 subfamily
FPL01_RS07490	COG4641	Protein conserved in bacteria
FPL01_RS07505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS07520	COG1136	(ABC) transporter
FPL01_RS07580	COG2186	Transcriptional regulator
FPL01_RS07605	COG0697	spore germination
FPL01_RS07610	COG2814	Major facilitator Superfamily
FPL01_RS07615	COG1309	transcriptional regulator
FPL01_RS07620	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS07625	COG1522	sequence-specific DNA binding
FPL01_RS07640	COG0346	lactoylglutathione lyase activity
FPL01_RS07695	COG2814	Major facilitator Superfamily
FPL01_RS07705	COG4895	conserved protein (DUF2196)
FPL01_RS07715	COG1063	alcohol dehydrogenase
FPL01_RS07760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FPL01_RS07770	COG2309	aminopeptidase activity
FPL01_RS07775	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FPL01_RS07795	COG0577	efflux transmembrane transporter activity
FPL01_RS07810	COG3850	Histidine kinase
FPL01_RS07810	COG5002	protein histidine kinase activity
FPL01_RS07820	COG2364	Membrane
FPL01_RS07825	COG1846	Transcriptional regulator
FPL01_RS07830	COG0456	acetyltransferase
FPL01_RS07835	COG2808	Putative FMN-binding domain
FPL01_RS07840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS07845	COG2271	Major facilitator Superfamily
FPL01_RS07850	COG1556	Lactate utilization protein
FPL01_RS07855	COG1139	Iron-sulfur cluster binding protein
FPL01_RS07865	COG0583	DNA-binding transcription factor activity
FPL01_RS07880	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPL01_RS07895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPL01_RS07920	COG0457	Tetratricopeptide repeat
FPL01_RS07985	COG0477	Major facilitator Superfamily
FPL01_RS08000	COG1846	Transcriptional regulator
FPL01_RS08020	COG2076	Multidrug Resistance protein
FPL01_RS08035	COG2031	fatty acid transporter
FPL01_RS08045	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL01_RS08075	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FPL01_RS08095	COG1288	antiporter activity
FPL01_RS08110	COG0789	Transcriptional regulator
FPL01_RS08125	COG3620	sequence-specific DNA binding
FPL01_RS08140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FPL01_RS08165	COG0469	pyruvate kinase activity
FPL01_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS08185	COG1131	(ABC) transporter
FPL01_RS08210	COG1011	Hydrolase
FPL01_RS08245	COG0346	lactoylglutathione lyase activity
FPL01_RS08250	COG1940	carbohydrate kinase activity
FPL01_RS08255	COG0110	maltose O-acetyltransferase activity
FPL01_RS08270	COG0628	permease
FPL01_RS08295	COG2226	methyltransferase
FPL01_RS08305	COG0477	Major facilitator Superfamily
FPL01_RS08330	COG1253	flavin adenine dinucleotide binding
FPL01_RS08335	COG0789	Transcriptional regulator
FPL01_RS08345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPL01_RS08375	COG0697	spore germination
FPL01_RS08390	COG1357	PFAM Pentapeptide repeats (8 copies)
FPL01_RS08400	COG1335	isochorismatase
FPL01_RS08405	COG3813	Protein conserved in bacteria
FPL01_RS08410	COG2706	6-phosphogluconolactonase activity
FPL01_RS08415	COG1070	Carbohydrate kinase
FPL01_RS08425	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPL01_RS08430	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPL01_RS08440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPL01_RS08455	COG0814	amino acid
FPL01_RS08485	COG2188	Transcriptional regulator
FPL01_RS08490	COG0673	inositol 2-dehydrogenase activity
FPL01_RS08505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS08520	COG0384	phenazine biosynthesis protein PhzF
FPL01_RS08535	COG0318	PFAM AMP-dependent synthetase and ligase
FPL01_RS08560	COG1191	sigma factor activity
FPL01_RS08605	COG1151	hydroxylamine reductase activity
FPL01_RS08645	COG0789	Transcriptional regulator
FPL01_RS08660	COG2072	flavoprotein involved in K transport
FPL01_RS08710	COG1695	Transcriptional regulator
FPL01_RS08715	COG0604	alcohol dehydrogenase
FPL01_RS08720	COG1113	amino acid transport
FPL01_RS08765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPL01_RS08780	COG1247	-acetyltransferase
FPL01_RS08785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL01_RS08790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS08795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS08800	COG3739	integral membrane protein
FPL01_RS08850	COG1476	TRANSCRIPTIONal
FPL01_RS08855	COG1476	TRANSCRIPTIONal
FPL01_RS08875	COG0583	DNA-binding transcription factor activity
FPL01_RS08885	COG2890	protein-(glutamine-N5) methyltransferase activity
FPL01_RS08900	COG1193	negative regulation of DNA recombination
FPL01_RS08905	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FPL01_RS08910	COG1164	Oligoendopeptidase f
FPL01_RS08930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPL01_RS08970	COG0640	Transcriptional regulator
FPL01_RS08975	COG0604	alcohol dehydrogenase
FPL01_RS08985	COG0457	Tetratricopeptide repeat
FPL01_RS09000	COG0456	acetyltransferase
FPL01_RS09000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPL01_RS09010	COG0385	Bile acid
FPL01_RS09015	COG0277	FAD linked oxidase domain protein
FPL01_RS09065	COG1285	pathogenesis
FPL01_RS09090	COG1126	abc transporter atp-binding protein
FPL01_RS09095	COG0765	amino acid transport
FPL01_RS09100	COG2720	vancomycin resistance protein
FPL01_RS09135	COG0716	FMN binding
FPL01_RS09145	COG0494	nUDIX hydrolase
FPL01_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS09175	COG0165	Argininosuccinate lyase
FPL01_RS09190	COG4145	pantothenate transmembrane transporter activity
FPL01_RS09200	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS09215	COG1657	PFAM Prenyltransferase squalene oxidase
FPL01_RS09220	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FPL01_RS09230	COG3326	Membrane
FPL01_RS09245	COG0489	protein tyrosine kinase activity
FPL01_RS09260	COG0303	'Molybdopterin
FPL01_RS09265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPL01_RS09270	COG2116	formate transmembrane transporter activity
FPL01_RS09280	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FPL01_RS09285	COG5609	conserved protein (DUF2294)
FPL01_RS09290	COG2427	Protein of unknown function (DUF1641)
FPL01_RS09295	COG3383	formate dehydrogenase (NAD+) activity
FPL01_RS09350	COG2226	methyltransferase
FPL01_RS09360	COG4166	transmembrane transport
FPL01_RS09365	COG4166	transmembrane transport
FPL01_RS09370	COG1301	dicarboxylic acid transport
FPL01_RS09375	COG1316	TRANSCRIPTIONal
FPL01_RS09385	COG1595	DNA-templated transcription, initiation
FPL01_RS09395	COG1131	(ABC) transporter
FPL01_RS09415	COG0673	inositol 2-dehydrogenase activity
FPL01_RS09420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPL01_RS09430	COG1832	CoA-binding protein
FPL01_RS09435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPL01_RS09440	COG0745	RESPONSE REGULATOR receiver
FPL01_RS09460	COG4841	protein insertion into membrane
FPL01_RS09465	COG0824	Thioesterase
FPL01_RS09495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS09510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FPL01_RS09540	COG2211	Major facilitator Superfamily
FPL01_RS09565	COG0183	Belongs to the thiolase family
FPL01_RS09570	COG0318	PFAM AMP-dependent synthetase and ligase
FPL01_RS09575	COG1268	BioY protein
FPL01_RS09580	COG0318	PFAM AMP-dependent synthetase and ligase
FPL01_RS09595	COG1396	sequence-specific DNA binding
FPL01_RS09615	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FPL01_RS09635	COG0830	nickel cation binding
FPL01_RS09675	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS09685	COG5002	protein histidine kinase activity
FPL01_RS09690	COG0400	carboxylic ester hydrolase activity
FPL01_RS09695	COG0346	lactoylglutathione lyase activity
FPL01_RS09700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPL01_RS09715	COG1902	pentaerythritol trinitrate reductase activity
FPL01_RS09720	COG0010	Belongs to the arginase family
FPL01_RS09745	COG2226	methyltransferase
FPL01_RS09790	COG0785	Cytochrome C biogenesis protein
FPL01_RS09805	COG1473	amidohydrolase
FPL01_RS09815	COG1131	(ABC) transporter
FPL01_RS09825	COG0583	DNA-binding transcription factor activity
FPL01_RS09835	COG1346	cytolysis
FPL01_RS09850	COG0730	response to heat
FPL01_RS09860	COG5632	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS09860	COG3409	Peptidoglycan-binding domain 1 protein
FPL01_RS09880	COG1132	(ABC) transporter
FPL01_RS09885	COG1132	(ABC) transporter
FPL01_RS09910	COG3639	organic phosphonate transmembrane transporter activity
FPL01_RS09915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FPL01_RS09920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL01_RS09925	COG0737	Belongs to the 5'-nucleotidase family
FPL01_RS09935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FPL01_RS09955	COG1695	Transcriptional regulator
FPL01_RS09960	COG0174	glutamine synthetase
FPL01_RS09965	COG0789	Transcriptional regulator
FPL01_RS09970	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
FPL01_RS09975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPL01_RS09980	COG2860	membrane
FPL01_RS10030	COG3584	3D domain protein
FPL01_RS10030	COG1388	LysM domain
FPL01_RS10035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPL01_RS10035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FPL01_RS10035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL01_RS10040	COG1105	Belongs to the carbohydrate kinase PfkB family
FPL01_RS10045	COG1349	DNA-binding transcription factor activity
FPL01_RS10050	COG1979	alcohol dehydrogenase
FPL01_RS10055	COG2322	membrane
FPL01_RS10065	COG1113	amino acid transport
FPL01_RS10075	COG1408	metallophosphoesterase
FPL01_RS10095	COG2217	Heavy metal translocating P-type atpase
FPL01_RS10100	COG2608	mercury ion transmembrane transporter activity
FPL01_RS10105	COG1937	Protein conserved in bacteria
FPL01_RS10115	COG1230	cation diffusion facilitator family transporter
FPL01_RS10135	COG2819	hydrolase of the alpha beta superfamily
FPL01_RS10140	COG1120	ATPase activity
FPL01_RS10145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS10150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS10155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL01_RS10165	COG2169	Transcriptional regulator
FPL01_RS10170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPL01_RS10175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPL01_RS10185	COG2364	Membrane
FPL01_RS10205	COG0346	lactoylglutathione lyase activity
FPL01_RS10210	COG5001	Diguanylate cyclase
FPL01_RS10210	COG3300	MHYT domain
FPL01_RS10240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS10265	COG1404	Belongs to the peptidase S8 family
FPL01_RS10270	COG3773	Cell wall hydrolase
FPL01_RS10280	COG1368	sulfuric ester hydrolase activity
FPL01_RS10285	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPL01_RS10295	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
FPL01_RS10315	COG4550	Control of competence regulator ComK, YlbF/YmcA
FPL01_RS10325	COG1013	pyruvate-flavodoxin oxidoreductase activity
FPL01_RS10330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FPL01_RS10330	COG0674	pyruvate-flavodoxin oxidoreductase activity
FPL01_RS10340	COG2359	stage V sporulation protein S
FPL01_RS10345	COG1692	metallophosphoesterase
FPL01_RS10365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FPL01_RS10385	COG0300	oxidoreductase activity
FPL01_RS10390	COG0612	Peptidase, M16
FPL01_RS10395	COG0612	Peptidase, M16
FPL01_RS10420	COG2188	Transcriptional regulator
FPL01_RS10425	COG1674	ftsk spoiiie
FPL01_RS10435	COG0740	serine-type endopeptidase activity
FPL01_RS10440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPL01_RS10450	COG0527	aspartate kinase activity
FPL01_RS10455	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPL01_RS10460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPL01_RS10465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPL01_RS10470	COG1873	PFAM PRC-barrel domain
FPL01_RS10475	COG0612	Peptidase, M16
FPL01_RS10480	COG0726	polysaccharide deacetylase
FPL01_RS10495	COG0196	riboflavin kinase activity
FPL01_RS10510	COG1550	Protein conserved in bacteria
FPL01_RS10520	COG1358	cellular component organization or biogenesis
FPL01_RS10525	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FPL01_RS10530	COG0195	Participates in both transcription termination and antitermination
FPL01_RS10550	COG0750	zinc metalloprotease
FPL01_RS10560	COG4589	Belongs to the CDS family
FPL01_RS10575	COG0528	UMP kinase activity
FPL01_RS10605	COG4974	Belongs to the 'phage' integrase family
FPL01_RS10615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPL01_RS10625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FPL01_RS10665	COG1837	Belongs to the UPF0109 family
FPL01_RS10675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FPL01_RS10685	COG0552	protein localization to endoplasmic reticulum
FPL01_RS10690	COG1196	nuclear chromosome segregation
FPL01_RS10700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPL01_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS10710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPL01_RS10725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPL01_RS10730	COG1461	Dihydroxyacetone kinase
FPL01_RS10735	COG1302	Protein conserved in bacteria
FPL01_RS10755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FPL01_RS10765	COG2815	serine threonine protein kinase
FPL01_RS10765	COG0515	serine threonine protein kinase
FPL01_RS10770	COG0631	protein serine/threonine phosphatase activity
FPL01_RS10780	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPL01_RS10780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPL01_RS10790	COG0242	peptide deformylase activity
FPL01_RS10795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FPL01_RS10800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPL01_RS10820	COG1561	YicC-like family, N-terminal region
FPL01_RS10850	COG0006	proline dipeptidase activity
FPL01_RS10870	COG3069	C4-dicarboxylate transmembrane transporter activity
FPL01_RS10930	COG0564	pseudouridine synthase activity
FPL01_RS10950	COG3599	regulation of cell shape
FPL01_RS10955	COG2302	S4 RNA-binding domain
FPL01_RS10970	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPL01_RS10980	COG1873	PFAM PRC-barrel domain
FPL01_RS10985	COG1191	sigma factor activity
FPL01_RS10990	COG1191	sigma factor activity
FPL01_RS11000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FPL01_RS11005	COG0849	cell division
FPL01_RS11010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FPL01_RS11025	COG0772	Belongs to the SEDS family
FPL01_RS11040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPL01_RS11045	COG0768	penicillin binding
FPL01_RS11070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FPL01_RS11085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FPL01_RS11090	COG1399	metal-binding, possibly nucleic acid-binding protein
FPL01_RS11100	COG3480	Lon protease (S16) C-terminal proteolytic domain
FPL01_RS11105	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPL01_RS11110	COG3314	Sporulation integral membrane protein YlbJ
FPL01_RS11120	COG0742	ribosomal rna small subunit methyltransferase
FPL01_RS11140	COG3679	Belongs to the UPF0342 family
FPL01_RS11145	COG0406	alpha-ribazole phosphatase activity
FPL01_RS11160	COG2340	Cysteine-rich secretory protein family
FPL01_RS11170	COG3336	cytochrome c oxidase
FPL01_RS11185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPL01_RS11205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FPL01_RS11220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPL01_RS11225	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FPL01_RS11235	COG4896	Protein conserved in bacteria
FPL01_RS11260	COG0483	inositol monophosphate 1-phosphatase activity
FPL01_RS11280	COG1982	Orn Lys Arg decarboxylase major
FPL01_RS11330	COG0022	dehydrogenase e1 component
FPL01_RS11335	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPL01_RS11345	COG0242	peptide deformylase activity
FPL01_RS11350	COG0561	phosphatase activity
FPL01_RS11360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPL01_RS11365	COG0569	domain protein
FPL01_RS11385	COG0583	DNA-binding transcription factor activity
FPL01_RS11390	COG0517	IMP dehydrogenase activity
FPL01_RS11405	COG4703	Protein of unknown function (DUF1797)
FPL01_RS11420	COG2200	EAL domain
FPL01_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS11430	COG1408	metallophosphoesterase
FPL01_RS11440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FPL01_RS11475	COG2814	Major facilitator Superfamily
FPL01_RS11495	COG3209	COG3209 Rhs family protein
FPL01_RS11505	COG2205	protein histidine kinase activity
FPL01_RS11515	COG0436	Aminotransferase
FPL01_RS11520	COG1609	Transcriptional regulator
FPL01_RS11525	COG3833	ABC-type maltose transport systems, permease component
FPL01_RS11530	COG1175	transmembrane transport
FPL01_RS11535	COG2182	Extracellular solute-binding protein
FPL01_RS11545	COG0366	Alpha amylase catalytic
FPL01_RS11550	COG3842	ATPase activity
FPL01_RS11590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPL01_RS11595	COG0183	Belongs to the thiolase family
FPL01_RS11630	COG1695	Transcriptional regulator
FPL01_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS11655	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPL01_RS11660	COG0436	Aminotransferase
FPL01_RS11695	COG2084	Dehydrogenase
FPL01_RS11705	COG3706	GGDEF domain
FPL01_RS11710	COG0778	Nitroreductase
FPL01_RS11740	COG3711	transcriptional antiterminator
FPL01_RS11750	COG2188	Transcriptional regulator
FPL01_RS11760	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPL01_RS11785	COG1547	Domain of unknown function (DUF309)
FPL01_RS11790	COG0456	acetyltransferase
FPL01_RS11795	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FPL01_RS11800	COG4086	secreted protein
FPL01_RS11805	COG0561	phosphatase activity
FPL01_RS11810	COG0697	spore germination
FPL01_RS11825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL01_RS11850	COG0733	neurotransmitter:sodium symporter activity
FPL01_RS11870	COG1686	Belongs to the peptidase S11 family
FPL01_RS11875	COG1725	Transcriptional regulator
FPL01_RS11880	COG1131	(ABC) transporter
FPL01_RS11900	COG1846	Transcriptional regulator
FPL01_RS11915	COG0598	Magnesium transport protein CorA
FPL01_RS11950	COG0735	belongs to the Fur family
FPL01_RS11955	COG1300	Membrane
FPL01_RS11975	COG0667	Aldo Keto reductase
FPL01_RS11980	COG0656	L-ascorbic acid biosynthetic process
FPL01_RS11985	COG0456	acetyltransferase
FPL01_RS11985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FPL01_RS11995	COG4085	toxin activity
FPL01_RS11995	COG1525	nuclease
FPL01_RS11995	COG0737	Belongs to the 5'-nucleotidase family
FPL01_RS12010	COG2056	Na+-H+ antiporter family
FPL01_RS12020	COG0456	acetyltransferase
FPL01_RS12025	COG1073	alpha beta
FPL01_RS12045	COG0307	riboflavin synthase, alpha
FPL01_RS12070	COG4106	trans-aconitate 2-methyltransferase activity
FPL01_RS12075	COG2226	methyltransferase
FPL01_RS12075	COG1073	alpha beta
FPL01_RS12090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPL01_RS12105	COG0737	Belongs to the 5'-nucleotidase family
FPL01_RS12115	COG1522	sequence-specific DNA binding
FPL01_RS12135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPL01_RS12160	COG0300	oxidoreductase activity
FPL01_RS12165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS12175	COG1760	l-serine dehydratase
FPL01_RS12180	COG1760	l-serine dehydratase
FPL01_RS12205	COG1285	pathogenesis
FPL01_RS12220	COG2195	Cleaves the N-terminal amino acid of tripeptides
FPL01_RS12240	COG1376	ErfK ybiS ycfS ynhG family protein
FPL01_RS12245	COG4129	membrane
FPL01_RS12250	COG1126	abc transporter atp-binding protein
FPL01_RS12255	COG0765	amino acid transport
FPL01_RS12260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL01_RS12280	COG2323	membrane
FPL01_RS12285	COG0772	Belongs to the SEDS family
FPL01_RS12290	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPL01_RS12295	COG0022	dehydrogenase e1 component
FPL01_RS12300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPL01_RS12305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPL01_RS12320	COG0280	phosphate acetyltransferase
FPL01_RS12325	COG3829	transcription factor binding
FPL01_RS12325	COG3290	protein histidine kinase activity
FPL01_RS12335	COG0584	glycerophosphoryl diester phosphodiesterase
FPL01_RS12340	COG3093	addiction module antidote protein HigA
FPL01_RS12345	COG0745	RESPONSE REGULATOR receiver
FPL01_RS12350	COG0750	zinc metalloprotease
FPL01_RS12355	COG0497	DNA recombination
FPL01_RS12365	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FPL01_RS12375	COG0142	geranyltranstransferase activity
FPL01_RS12400	COG1302	Protein conserved in bacteria
FPL01_RS12405	COG0439	Biotin carboxylase
FPL01_RS12410	COG0511	ligase activity, forming carbon-carbon bonds
FPL01_RS12455	COG3854	ATPases associated with a variety of cellular activities
FPL01_RS12480	COG0006	proline dipeptidase activity
FPL01_RS12505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FPL01_RS12535	COG0095	Lipoate-protein ligase
FPL01_RS12540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL01_RS12550	COG1609	Transcriptional regulator
FPL01_RS12560	COG2076	Multidrug Resistance protein
FPL01_RS12565	COG2076	Multidrug Resistance protein
FPL01_RS12605	COG1725	Transcriptional regulator
FPL01_RS12635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPL01_RS12655	COG0675	Transposase, IS605 OrfB family
FPL01_RS12695	COG4970	Tfp pilus assembly protein FimT
FPL01_RS12705	COG1459	type II secretion system
FPL01_RS12710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FPL01_RS12765	COG0646	methionine synthase
FPL01_RS12765	COG1410	methionine synthase
FPL01_RS12770	COG0646	methionine synthase
FPL01_RS12770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FPL01_RS12775	COG0626	cystathionine gamma-synthase activity
FPL01_RS12780	COG0626	cystathionine gamma-synthase activity
FPL01_RS12800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS12810	COG1940	carbohydrate kinase activity
FPL01_RS12815	COG4483	Protein conserved in bacteria
FPL01_RS12820	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPL01_RS12825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPL01_RS12830	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FPL01_RS12835	COG0704	Plays a role in the regulation of phosphate uptake
FPL01_RS12845	COG0581	inorganic phosphate transmembrane transporter activity
FPL01_RS12850	COG0573	inorganic phosphate transmembrane transporter activity
FPL01_RS12855	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPL01_RS12865	COG0477	Major facilitator Superfamily
FPL01_RS12870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPL01_RS12895	COG0735	belongs to the Fur family
FPL01_RS12900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPL01_RS12905	COG1121	(ABC) transporter
FPL01_RS12910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS12940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FPL01_RS12945	COG2384	SAM-dependent methyltransferase
FPL01_RS12955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPL01_RS12960	COG0358	DNA primase activity
FPL01_RS12975	COG0517	IMP dehydrogenase activity
FPL01_RS12990	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPL01_RS12995	COG0295	cytidine deaminase activity
FPL01_RS13000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FPL01_RS13015	COG1702	phosphate starvation-inducible protein PhoH
FPL01_RS13030	COG1610	YqeY-like protein
FPL01_RS13035	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FPL01_RS13040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPL01_RS13045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPL01_RS13075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPL01_RS13080	COG1733	regulation of RNA biosynthetic process
FPL01_RS13105	COG1466	dna polymerase III delta subunit
FPL01_RS13115	COG0658	competence protein
FPL01_RS13115	COG2333	competence protein COMEC
FPL01_RS13120	COG2131	deaminase
FPL01_RS13125	COG1596	polysaccharide export
FPL01_RS13125	COG1555	photosystem II stabilization
FPL01_RS13130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPL01_RS13135	COG2226	methyltransferase
FPL01_RS13140	COG0799	negative regulation of ribosome biogenesis
FPL01_RS13145	COG1713	HD superfamily hydrolase involved in NAD metabolism
FPL01_RS13155	COG1534	Rna-binding protein
FPL01_RS13165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FPL01_RS13170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FPL01_RS13205	COG2357	RelA SpoT domain protein
FPL01_RS13215	COG1785	Belongs to the alkaline phosphatase family
FPL01_RS13225	COG2267	carboxylic ester hydrolase activity
FPL01_RS13260	COG1404	Belongs to the peptidase S8 family
FPL01_RS13265	COG3186	Phenylalanine-4-hydroxylase
FPL01_RS13275	COG2514	catechol 2,3-dioxygenase activity
FPL01_RS13280	COG2259	Doxx family
FPL01_RS13320	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FPL01_RS13330	COG1454	alcohol dehydrogenase
FPL01_RS13330	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS13335	COG0626	cystathionine gamma-synthase activity
FPL01_RS13340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPL01_RS13365	COG0768	penicillin binding
FPL01_RS13390	COG4122	O-methyltransferase activity
FPL01_RS13395	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FPL01_RS13425	COG0628	permease
FPL01_RS13445	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FPL01_RS13460	COG1104	cysteine desulfurase activity
FPL01_RS13465	COG1959	2 iron, 2 sulfur cluster binding
FPL01_RS13470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FPL01_RS13480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FPL01_RS13510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FPL01_RS13520	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPL01_RS13520	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FPL01_RS13525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPL01_RS13530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPL01_RS13530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPL01_RS13540	COG2244	polysaccharide biosynthetic process
FPL01_RS13545	COG2323	membrane
FPL01_RS13555	COG1862	Preprotein translocase
FPL01_RS13595	COG0640	Transcriptional regulator
FPL01_RS13625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FPL01_RS13630	COG1104	cysteine desulfurase activity
FPL01_RS13635	COG1827	regulation of RNA biosynthetic process
FPL01_RS13640	COG2258	MOSC domain
FPL01_RS13645	COG0077	Prephenate dehydratase
FPL01_RS13650	COG0577	efflux transmembrane transporter activity
FPL01_RS13655	COG0577	efflux transmembrane transporter activity
FPL01_RS13660	COG1136	(ABC) transporter
FPL01_RS13665	COG5002	protein histidine kinase activity
FPL01_RS13670	COG0745	RESPONSE REGULATOR receiver
FPL01_RS13680	COG3290	protein histidine kinase activity
FPL01_RS13690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPL01_RS13695	COG1530	ribonuclease E activity
FPL01_RS13705	COG0739	heme binding
FPL01_RS13710	COG2894	cell division
FPL01_RS13730	COG1077	Cell shape determining protein MreB Mrl
FPL01_RS13750	COG0285	dihydrofolate synthase activity
FPL01_RS13765	COG1388	LysM domain
FPL01_RS13775	COG0113	porphobilinogen synthase activity
FPL01_RS13780	COG1587	Uroporphyrinogen-III synthase
FPL01_RS13790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPL01_RS13800	COG1846	Transcriptional regulator
FPL01_RS13805	COG1764	response to oxidative stress
FPL01_RS13820	COG0470	DNA polymerase III
FPL01_RS13820	COG1067	ATP-dependent peptidase activity
FPL01_RS13860	COG0457	Tetratricopeptide repeat
FPL01_RS13880	COG0622	Phosphoesterase
FPL01_RS13895	COG5401	PFAM Sporulation and spore germination
FPL01_RS13915	COG1309	transcriptional regulator
FPL01_RS13930	COG2197	response regulator
FPL01_RS13935	COG2233	PERMEase
FPL01_RS13940	COG0402	S-adenosylhomocysteine deaminase activity
FPL01_RS13950	COG1396	sequence-specific DNA binding
FPL01_RS13955	COG0697	spore germination
FPL01_RS13965	COG1959	2 iron, 2 sulfur cluster binding
FPL01_RS13970	COG1668	transmembrane transport
FPL01_RS13975	COG4152	abc transporter atp-binding protein
FPL01_RS13980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FPL01_RS13985	COG1360	Flagellar Motor Protein
FPL01_RS13990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FPL01_RS13995	COG1876	peptidase activity
FPL01_RS14000	COG0824	Thioesterase
FPL01_RS14005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPL01_RS14010	COG1053	succinate dehydrogenase
FPL01_RS14015	COG2009	succinate dehydrogenase
FPL01_RS14020	COG1719	4-vinyl reductase, 4VR
FPL01_RS14030	COG3118	belongs to the thioredoxin family
FPL01_RS14040	COG2086	electron transfer activity
FPL01_RS14045	COG1024	Enoyl-CoA hydratase
FPL01_RS14050	COG1309	transcriptional regulator
FPL01_RS14055	COG0318	PFAM AMP-dependent synthetase and ligase
FPL01_RS14065	COG2318	DinB family
FPL01_RS14085	COG1131	(ABC) transporter
FPL01_RS14095	COG0745	RESPONSE REGULATOR receiver
FPL01_RS14100	COG4895	conserved protein (DUF2196)
FPL01_RS14115	COG4509	Sortase family
FPL01_RS14135	COG5386	Cell surface protein
FPL01_RS14140	COG5386	Cell surface protein
FPL01_RS14145	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS14150	COG1187	pseudouridine synthase activity
FPL01_RS14160	COG1796	DNA polymerase
FPL01_RS14160	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPL01_RS14165	COG1286	toxin biosynthetic process
FPL01_RS14210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPL01_RS14220	COG1418	mRNA catabolic process
FPL01_RS14255	COG2814	Major facilitator Superfamily
FPL01_RS14260	COG1566	PFAM secretion protein HlyD family protein
FPL01_RS14265	COG1309	transcriptional regulator
FPL01_RS14270	COG1363	Peptidase, m42
FPL01_RS14295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPL01_RS14305	COG1484	DNA-dependent DNA replication
FPL01_RS14310	COG3611	Membrane attachment protein
FPL01_RS14320	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPL01_RS14325	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPL01_RS14345	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPL01_RS14345	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPL01_RS14350	COG5002	protein histidine kinase activity
FPL01_RS14375	COG0538	isocitrate dehydrogenase activity
FPL01_RS14380	COG0372	Belongs to the citrate synthase family
FPL01_RS14390	COG0628	permease
FPL01_RS14395	COG3030	protein affecting phage T7 exclusion by the F plasmid
FPL01_RS14420	COG1725	Transcriptional regulator
FPL01_RS14425	COG0281	malic enzyme
FPL01_RS14445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPL01_RS14470	COG4109	DRTGG domain
FPL01_RS14480	COG0006	proline dipeptidase activity
FPL01_RS14515	COG0662	Cupin 2, conserved barrel domain protein
FPL01_RS14525	COG1476	TRANSCRIPTIONal
FPL01_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS14545	COG0589	response to stress
FPL01_RS14590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS14615	COG0827	DNA restriction-modification system
FPL01_RS14620	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FPL01_RS14625	COG3874	Sporulation protein YtfJ
FPL01_RS14640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FPL01_RS14650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPL01_RS14665	COG1104	cysteine desulfurase activity
FPL01_RS14675	COG0583	DNA-binding transcription factor activity
FPL01_RS14680	COG0697	spore germination
FPL01_RS14685	COG1309	transcriptional regulator
FPL01_RS14690	COG1956	GAF domain-containing protein
FPL01_RS14695	COG0626	cystathionine gamma-synthase activity
FPL01_RS14820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPL01_RS14825	COG0454	-acetyltransferase
FPL01_RS14830	COG0517	IMP dehydrogenase activity
FPL01_RS14835	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPL01_RS14880	COG1609	Transcriptional regulator
FPL01_RS14885	COG4851	CamS sex pheromone cAM373 precursor
FPL01_RS14890	COG3118	belongs to the thioredoxin family
FPL01_RS14900	COG2309	aminopeptidase activity
FPL01_RS14925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS14930	COG0697	spore germination
FPL01_RS14935	COG0789	Transcriptional regulator
FPL01_RS14940	COG1695	Transcriptional regulator
FPL01_RS14970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL01_RS14980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS14985	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FPL01_RS14990	COG1363	Peptidase, m42
FPL01_RS15000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS15020	COG1523	belongs to the glycosyl hydrolase 13 family
FPL01_RS15030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL01_RS15035	COG1349	DNA-binding transcription factor activity
FPL01_RS15040	COG1187	pseudouridine synthase activity
FPL01_RS15045	COG2244	polysaccharide biosynthetic process
FPL01_RS15055	COG2814	Major facilitator Superfamily
FPL01_RS15065	COG3832	glyoxalase III activity
FPL01_RS15085	COG1329	Transcriptional regulator
FPL01_RS15110	COG0314	molybdopterin synthase activity
FPL01_RS15115	COG1763	Mo-molybdopterin cofactor biosynthetic process
FPL01_RS15120	COG0303	'Molybdopterin
FPL01_RS15130	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPL01_RS15135	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FPL01_RS15155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL01_RS15165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPL01_RS15215	COG2814	Major facilitator Superfamily
FPL01_RS15220	COG0475	glutathione-regulated potassium exporter activity
FPL01_RS15225	COG0490	domain, Protein
FPL01_RS15230	COG0582	viral genome integration into host DNA
FPL01_RS15240	COG1136	(ABC) transporter
FPL01_RS15260	COG1242	4 iron, 4 sulfur cluster binding
FPL01_RS15265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FPL01_RS15280	COG1794	racemase activity, acting on amino acids and derivatives
FPL01_RS15295	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPL01_RS15315	COG2267	carboxylic ester hydrolase activity
FPL01_RS15320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FPL01_RS15325	COG0671	phosphoesterase, PA-phosphatase related
FPL01_RS15340	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPL01_RS15350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS15390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FPL01_RS15405	COG5002	protein histidine kinase activity
FPL01_RS15410	COG4191	Histidine kinase
FPL01_RS15415	COG2267	carboxylic ester hydrolase activity
FPL01_RS15445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPL01_RS15450	COG1116	anion transmembrane transporter activity
FPL01_RS15455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPL01_RS15475	COG0494	nUDIX hydrolase
FPL01_RS15510	COG0288	reversible hydration of carbon dioxide
FPL01_RS15515	COG1271	oxidase subunit
FPL01_RS15520	COG1294	oxidase, subunit
FPL01_RS15540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS15565	COG1842	Phage shock protein A
FPL01_RS15620	COG0745	RESPONSE REGULATOR receiver
FPL01_RS15650	COG1597	lipid kinase activity
FPL01_RS15670	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS15680	COG0577	efflux transmembrane transporter activity
FPL01_RS15685	COG1136	(ABC) transporter
FPL01_RS15690	COG3708	Transcriptional regulator
FPL01_RS15690	COG2207	Transcriptional regulator
FPL01_RS15695	COG5658	integral membrane protein
FPL01_RS15700	COG0640	Transcriptional regulator
FPL01_RS15705	COG0745	RESPONSE REGULATOR receiver
FPL01_RS15710	COG2205	protein histidine kinase activity
FPL01_RS15715	COG0577	efflux transmembrane transporter activity
FPL01_RS15725	COG1136	(ABC) transporter
FPL01_RS15730	COG0577	efflux transmembrane transporter activity
FPL01_RS15755	COG2188	Transcriptional regulator
FPL01_RS15805	COG4948	Mandelate Racemase Muconate Lactonizing
FPL01_RS15815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FPL01_RS15820	COG0596	Alpha beta hydrolase
FPL01_RS15830	COG1169	isochorismate synthase
FPL01_RS15835	COG1575	Belongs to the MenA family. Type 1 subfamily
FPL01_RS15840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FPL01_RS15855	COG0789	Transcriptional regulator
FPL01_RS15865	COG0058	SHG alpha-glucan phosphorylase activity
FPL01_RS15875	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FPL01_RS15895	COG1404	Belongs to the peptidase S8 family
FPL01_RS15995	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPL01_RS16030	COG1285	pathogenesis
FPL01_RS16035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPL01_RS16050	COG2155	Conserved Protein
FPL01_RS16055	COG1098	S1 RNA binding domain
FPL01_RS16060	COG0436	Aminotransferase
FPL01_RS16065	COG1522	sequence-specific DNA binding
FPL01_RS16070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPL01_RS16075	COG2267	carboxylic ester hydrolase activity
FPL01_RS16085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FPL01_RS16100	COG5018	Exonuclease
FPL01_RS16105	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FPL01_RS16125	COG2050	protein possibly involved in aromatic compounds catabolism
FPL01_RS16135	COG1268	BioY protein
FPL01_RS16140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPL01_RS16145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPL01_RS16160	COG3584	3D domain protein
FPL01_RS16175	COG1252	NADH dehydrogenase
FPL01_RS16185	COG3708	Transcriptional regulator
FPL01_RS16200	COG1683	Conserved Protein
FPL01_RS16210	COG0316	Belongs to the HesB IscA family
FPL01_RS16225	COG1252	NADH dehydrogenase
FPL01_RS16235	COG2274	protein secretion by the type I secretion system
FPL01_RS16240	COG0390	transport system, permease component
FPL01_RS16245	COG2824	Alkylphosphonate utilization operon protein PhnA
FPL01_RS16265	COG4837	Protein of unknown function (DUF1462)
FPL01_RS16270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FPL01_RS16280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FPL01_RS16285	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FPL01_RS16305	COG1358	cellular component organization or biogenesis
FPL01_RS16315	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL01_RS16320	COG0647	UMP catabolic process
FPL01_RS16330	COG2445	Protein of unknown function DUF86
FPL01_RS16335	COG1494	fructose-1,6-bisphosphatase
FPL01_RS16350	COG4470	Protein conserved in bacteria
FPL01_RS16360	COG0789	Transcriptional regulator
FPL01_RS16365	COG4377	Putative membrane peptidase family (DUF2324)
FPL01_RS16395	COG0739	heme binding
FPL01_RS16405	COG3377	Domain of unknown function (DUF1805)
FPL01_RS16410	COG0737	Belongs to the 5'-nucleotidase family
FPL01_RS16415	COG1695	Transcriptional regulator
FPL01_RS16425	COG0719	Fe-S assembly protein
FPL01_RS16430	COG0822	iron-sulfur transferase activity
FPL01_RS16435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPL01_RS16440	COG0719	Fe-S assembly protein
FPL01_RS16445	COG0396	ATPase activity
FPL01_RS16450	COG1464	Belongs to the NlpA lipoprotein family
FPL01_RS16455	COG1464	Belongs to the NlpA lipoprotein family
FPL01_RS16460	COG2011	ABC-type metal ion transport system permease component
FPL01_RS16475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS16480	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FPL01_RS16490	COG1393	Belongs to the ArsC family
FPL01_RS16535	COG1309	transcriptional regulator
FPL01_RS16540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS16545	COG1960	acyl-CoA dehydrogenase activity
FPL01_RS16550	COG0183	Belongs to the thiolase family
FPL01_RS16555	COG1024	Enoyl-CoA hydratase
FPL01_RS16555	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPL01_RS16565	COG1686	Belongs to the peptidase S11 family
FPL01_RS16580	COG0011	TIGRFAM Protein of
FPL01_RS16585	COG0840	transmembrane signaling receptor activity
FPL01_RS16600	COG2814	Major facilitator Superfamily
FPL01_RS16605	COG0531	amino acid
FPL01_RS16625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS16635	COG5002	protein histidine kinase activity
FPL01_RS16640	COG0745	RESPONSE REGULATOR receiver
FPL01_RS16680	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS16690	COG1376	ErfK ybiS ycfS ynhG family protein
FPL01_RS16700	COG5002	protein histidine kinase activity
FPL01_RS16725	COG0840	transmembrane signaling receptor activity
FPL01_RS16730	COG2151	metal-sulfur cluster biosynthetic enzyme
FPL01_RS16735	COG3227	Zinc metalloprotease (Elastase)
FPL01_RS16740	COG1741	Belongs to the pirin family
FPL01_RS16755	COG0475	glutathione-regulated potassium exporter activity
FPL01_RS16760	COG0490	domain, Protein
FPL01_RS16765	COG1115	amino acid carrier protein
FPL01_RS16770	COG0783	Belongs to the Dps family
FPL01_RS16785	COG1611	Belongs to the LOG family
FPL01_RS16805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS16810	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS16815	COG1115	amino acid carrier protein
FPL01_RS16820	COG1115	amino acid carrier protein
FPL01_RS16825	COG2910	NAD(P)H-binding
FPL01_RS16840	COG0656	L-ascorbic acid biosynthetic process
FPL01_RS16845	COG2814	Major facilitator Superfamily
FPL01_RS16850	COG1733	regulation of RNA biosynthetic process
FPL01_RS16860	COG1252	NADH dehydrogenase
FPL01_RS16865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FPL01_RS16880	COG3290	protein histidine kinase activity
FPL01_RS16880	COG0840	transmembrane signaling receptor activity
FPL01_RS16890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FPL01_RS16910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FPL01_RS16955	COG2226	methyltransferase
FPL01_RS16965	COG1136	(ABC) transporter
FPL01_RS16980	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS16990	COG2311	Membrane
FPL01_RS16995	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FPL01_RS17010	COG0557	exoribonuclease II activity
FPL01_RS17015	COG1647	Serine aminopeptidase, S33
FPL01_RS17020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FPL01_RS17025	COG1346	cytolysis
FPL01_RS17060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FPL01_RS17075	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FPL01_RS17085	COG5294	Protein conserved in bacteria
FPL01_RS17105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL01_RS17120	COG2323	membrane
FPL01_RS17130	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FPL01_RS17140	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FPL01_RS17150	COG1051	belongs to the nudix hydrolase family
FPL01_RS17160	COG0492	ferredoxin-NADP+ reductase activity
FPL01_RS17165	COG0457	Tetratricopeptide repeat
FPL01_RS17170	COG0110	maltose O-acetyltransferase activity
FPL01_RS17190	COG1950	PFAM Membrane protein of
FPL01_RS17205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPL01_RS17225	COG0789	Transcriptional regulator
FPL01_RS17255	COG0583	DNA-binding transcription factor activity
FPL01_RS17265	COG0655	NAD(P)H dehydrogenase (quinone) activity
FPL01_RS17280	COG1132	(ABC) transporter
FPL01_RS17285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPL01_RS17290	COG3409	Peptidoglycan-binding domain 1 protein
FPL01_RS17290	COG0793	Belongs to the peptidase S41A family
FPL01_RS17295	COG2177	Part of the ABC transporter FtsEX involved in
FPL01_RS17300	COG2884	Cell division ATP-binding protein ftsE
FPL01_RS17320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FPL01_RS17325	COG1278	Cold shock
FPL01_RS17330	COG1040	competence protein
FPL01_RS17335	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FPL01_RS17340	COG0791	NLP P60 protein
FPL01_RS17340	COG1388	LysM domain
FPL01_RS17345	COG1733	regulation of RNA biosynthetic process
FPL01_RS17350	COG1307	EDD domain protein, DegV family
FPL01_RS17355	COG1739	Uncharacterized protein family UPF0029
FPL01_RS17360	COG1316	TRANSCRIPTIONal
FPL01_RS17365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FPL01_RS17370	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FPL01_RS17375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPL01_RS17385	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FPL01_RS17385	COG3933	PFAM sigma-54 factor interaction domain-containing protein
FPL01_RS17405	COG1486	melibiose metabolic process
FPL01_RS17410	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL01_RS17415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL01_RS17435	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL01_RS17445	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL01_RS17450	COG1301	dicarboxylic acid transport
FPL01_RS17460	COG0346	lactoylglutathione lyase activity
FPL01_RS17480	COG1511	domain protein
FPL01_RS17485	COG0583	DNA-binding transcription factor activity
FPL01_RS17495	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FPL01_RS17510	COG1271	oxidase subunit
FPL01_RS17515	COG1294	oxidase, subunit
FPL01_RS17520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FPL01_RS17530	COG1620	l-lactate permease
FPL01_RS17540	COG2389	metal-binding protein
FPL01_RS17550	COG1368	sulfuric ester hydrolase activity
FPL01_RS17560	COG0791	NLP P60 protein
FPL01_RS17560	COG1388	LysM domain
FPL01_RS17565	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS17575	COG1215	transferase activity, transferring glycosyl groups
FPL01_RS17580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPL01_RS17585	COG3584	3D domain protein
FPL01_RS17585	COG1388	LysM domain
FPL01_RS17600	COG4715	Zinc finger, swim domain protein
FPL01_RS17605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FPL01_RS17645	COG0577	efflux transmembrane transporter activity
FPL01_RS17650	COG1136	(ABC) transporter
FPL01_RS17670	COG2271	Major facilitator Superfamily
FPL01_RS17685	COG5002	protein histidine kinase activity
FPL01_RS17690	COG0745	RESPONSE REGULATOR receiver
FPL01_RS17695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPL01_RS17705	COG1316	TRANSCRIPTIONal
FPL01_RS17745	COG1216	Glycosyl transferase, family 2
FPL01_RS17760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FPL01_RS17775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FPL01_RS17780	COG1086	Polysaccharide biosynthesis protein
FPL01_RS17785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FPL01_RS17790	COG4464	protein tyrosine phosphatase activity
FPL01_RS17795	COG0489	protein tyrosine kinase activity
FPL01_RS17800	COG3944	biosynthesis protein
FPL01_RS17805	COG0489	protein tyrosine kinase activity
FPL01_RS17820	COG1609	Transcriptional regulator
FPL01_RS17830	COG0739	heme binding
FPL01_RS17845	COG3279	Response regulator of the LytR AlgR family
FPL01_RS17850	COG2385	sporulation resulting in formation of a cellular spore
FPL01_RS17865	COG4836	Membrane
FPL01_RS17870	COG1007	ATP synthesis coupled electron transport
FPL01_RS17875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPL01_RS17880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPL01_RS17890	COG0839	Belongs to the complex I subunit 6 family
FPL01_RS17975	COG0356	it plays a direct role in the translocation of protons across the membrane
FPL01_RS18010	COG0698	ribose 5-phosphate isomerase
FPL01_RS18020	COG2190	(PTS) system
FPL01_RS18025	COG2259	Doxx family
FPL01_RS18030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FPL01_RS18050	COG0009	L-threonylcarbamoyladenylate synthase
FPL01_RS18065	COG2890	protein-(glutamine-N5) methyltransferase activity
FPL01_RS18085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FPL01_RS18090	COG1494	fructose-1,6-bisphosphatase
FPL01_RS18110	COG4821	SIS domain
FPL01_RS18130	COG1960	acyl-CoA dehydrogenase activity
FPL01_RS18135	COG1960	acyl-CoA dehydrogenase activity
FPL01_RS18140	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPL01_RS18150	COG2181	nitrate reductase activity
FPL01_RS18150	COG0247	lactate metabolic process
FPL01_RS18155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPL01_RS18185	COG2197	response regulator
FPL01_RS18190	COG4585	Histidine kinase
FPL01_RS18195	COG0842	Transport permease protein
FPL01_RS18200	COG1131	(ABC) transporter
FPL01_RS18205	COG0024	Methionine aminopeptidase
FPL01_RS18220	COG2234	aminopeptidase activity
FPL01_RS18250	COG4506	Protein conserved in bacteria
FPL01_RS18255	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPL01_RS18285	COG2814	Major facilitator Superfamily
FPL01_RS18290	COG0789	Transcriptional regulator
FPL01_RS18295	COG0584	glycerophosphoryl diester phosphodiesterase
FPL01_RS18300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPL01_RS18310	COG1994	Peptidase M50
FPL01_RS18320	COG1078	dGTPase activity
FPL01_RS18325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL01_RS18330	COG1120	ATPase activity
FPL01_RS18335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS18340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS18360	COG0280	phosphate acetyltransferase
FPL01_RS18375	COG3773	Cell wall hydrolase
FPL01_RS18385	COG2363	Small membrane protein
FPL01_RS18395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPL01_RS18400	COG2233	PERMEase
FPL01_RS18405	COG0561	phosphatase activity
FPL01_RS18410	COG2814	Major facilitator Superfamily
FPL01_RS18420	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FPL01_RS18425	COG1131	(ABC) transporter
FPL01_RS18430	COG2755	lipolytic protein G-D-S-L family
FPL01_RS18435	COG1609	Transcriptional regulator
FPL01_RS18445	COG0460	homoserine dehydrogenase
FPL01_RS18455	COG2873	o-acetylhomoserine
FPL01_RS18465	COG1011	Hydrolase
FPL01_RS18470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPL01_RS18480	COG2197	response regulator
FPL01_RS18495	COG3706	GGDEF domain
FPL01_RS18500	COG2879	small protein
FPL01_RS18505	COG1966	Carbon starvation protein
FPL01_RS18510	COG3279	Response regulator of the LytR AlgR family
FPL01_RS18515	COG0477	Major facilitator Superfamily
FPL01_RS18525	COG0438	transferase activity, transferring glycosyl groups
FPL01_RS18540	COG0840	transmembrane signaling receptor activity
FPL01_RS18550	COG1607	acyl-coa hydrolase
FPL01_RS18555	COG1216	Glycosyl transferase, family 2
FPL01_RS18570	COG1216	Glycosyl transferase, family 2
FPL01_RS18575	COG0488	(ABC) transporter
FPL01_RS18580	COG1696	Membrane protein involved in D-alanine export
FPL01_RS18590	COG1309	transcriptional regulator
FPL01_RS18595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPL01_RS18600	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL01_RS18600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPL01_RS18605	COG0628	permease
FPL01_RS18620	COG3279	Response regulator of the LytR AlgR family
FPL01_RS18625	COG3275	phosphorelay sensor kinase activity
FPL01_RS18630	COG2814	Major facilitator Superfamily
FPL01_RS18635	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPL01_RS18640	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FPL01_RS18645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPL01_RS18690	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FPL01_RS18695	COG1272	protein, Hemolysin III
FPL01_RS18715	COG1164	Oligoendopeptidase f
FPL01_RS18730	COG0322	excinuclease ABC activity
FPL01_RS18795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPL01_RS18800	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FPL01_RS18810	COG4863	YycH protein
FPL01_RS18815	COG5002	protein histidine kinase activity
FPL01_RS18820	COG0745	RESPONSE REGULATOR receiver
FPL01_RS18860	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
FPL01_RS18865	COG4241	membrane
FPL01_RS18885	COG0012	GTP binding
FPL01_RS18890	COG4481	Protein conserved in bacteria
FPL01_RS18895	COG0668	transmembrane transport
FPL01_RS18905	COG1475	DNA binding
FPL01_RS18910	COG1192	Involved in chromosome partitioning
FPL01_RS18935	COG1847	R3H domain protein
FPL01_RS18940	COG0706	membrane insertase activity
FPL01_RS18950	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FPL01_RS18960	COG0592	DNA-directed DNA polymerase activity
FPL01_RS18965	COG2501	S4 domain
FPL01_RS18975	COG0187	DNA topoisomerase II activity
FPL01_RS19015	COG0517	IMP dehydrogenase activity
FPL01_RS19015	COG0516	GMP reductase activity
FPL01_RS19020	COG1686	Belongs to the peptidase S11 family
FPL01_RS19050	COG1428	Deoxynucleoside kinase
FPL01_RS19060	COG1335	isochorismatase
FPL01_RS19075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FPL01_RS19130	COG1982	Orn Lys Arg decarboxylase major
FPL01_RS19140	COG0470	DNA polymerase III
FPL01_RS19145	COG1774	PSP1 C-terminal conserved region
FPL01_RS19155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FPL01_RS19170	COG2002	toxin-antitoxin pair type II binding
FPL01_RS19175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL01_RS19175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPL01_RS19180	COG0084	hydrolase, TatD family'
FPL01_RS19185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FPL01_RS19200	COG4466	Protein conserved in bacteria
FPL01_RS19215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FPL01_RS19220	COG0251	oxidation-reduction process
FPL01_RS19255	COG2002	toxin-antitoxin pair type II binding
FPL01_RS19260	COG2244	polysaccharide biosynthetic process
FPL01_RS19265	COG3956	TIGRFAM MazG family protein
FPL01_RS19270	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FPL01_RS19290	COG1098	S1 RNA binding domain
FPL01_RS19305	COG2208	phosphoserine phosphatase activity
FPL01_RS19320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPL01_RS19335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPL01_RS19340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPL01_RS19345	COG0512	Glutamine amidotransferase of anthranilate synthase
FPL01_RS19350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPL01_RS19355	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FPL01_RS19360	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FPL01_RS19365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FPL01_RS19370	COG1396	sequence-specific DNA binding
FPL01_RS19375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPL01_RS19465	COG3880	PFAM UvrB UvrC protein
FPL01_RS19475	COG0542	response to heat
FPL01_RS19480	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FPL01_RS19490	COG4956	integral membrane protein (PIN domain superfamily)
FPL01_RS19510	COG1045	serine acetyltransferase
FPL01_RS19525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPL01_RS19530	COG3688	RNA-binding protein containing a PIN domain
FPL01_RS19545	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FPL01_RS19550	COG0250	Participates in transcription elongation, termination and antitermination
FPL01_RS19555	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FPL01_RS19590	COG1358	cellular component organization or biogenesis
FPL01_RS19660	COG0255	Belongs to the universal ribosomal protein uL29 family
FPL01_RS19720	COG0201	protein transport
FPL01_RS19730	COG0024	Methionine aminopeptidase
FPL01_RS19740	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FPL01_RS19745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FPL01_RS19775	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FPL01_RS19800	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS19805	COG0489	protein tyrosine kinase activity
FPL01_RS19815	COG2194	sulfuric ester hydrolase activity
FPL01_RS19820	COG0726	polysaccharide deacetylase
FPL01_RS19900	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FPL01_RS19905	COG4856	YbbR-like protein
FPL01_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS19975	COG0277	FAD linked oxidase domain protein
FPL01_RS19980	COG2271	Major facilitator Superfamily
FPL01_RS19990	COG2814	Major facilitator Superfamily
FPL01_RS20010	COG0601	transmembrane transport
FPL01_RS20015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPL01_RS20020	COG0444	Belongs to the ABC transporter superfamily
FPL01_RS20025	COG4608	Belongs to the ABC transporter superfamily
FPL01_RS20030	COG4166	transmembrane transport
FPL01_RS20045	COG1309	transcriptional regulator
FPL01_RS20055	COG4166	transmembrane transport
FPL01_RS20060	COG4166	transmembrane transport
FPL01_RS20065	COG0656	L-ascorbic acid biosynthetic process
FPL01_RS20085	COG4149	molybdate abc transporter
FPL01_RS20090	COG0725	ABC transporter, periplasmic molybdate-binding protein
FPL01_RS20095	COG1910	domain protein
FPL01_RS20110	COG0697	spore germination
FPL01_RS20125	COG0204	Acyl-transferase
FPL01_RS20135	COG1609	Transcriptional regulator
FPL01_RS20145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS20155	COG0084	hydrolase, TatD family'
FPL01_RS20165	COG5298	Protein conserved in bacteria
FPL01_RS20185	COG0488	(ABC) transporter
FPL01_RS20195	COG0747	negative chemotaxis
FPL01_RS20200	COG0747	negative chemotaxis
FPL01_RS20205	COG0601	transmembrane transport
FPL01_RS20215	COG0444	Belongs to the ABC transporter superfamily
FPL01_RS20220	COG4608	Belongs to the ABC transporter superfamily
FPL01_RS20225	COG0561	phosphatase activity
FPL01_RS20260	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPL01_RS20270	COG0531	amino acid
FPL01_RS20285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPL01_RS20300	COG0705	Rhomboid family
FPL01_RS20310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FPL01_RS20320	COG0864	Transcriptional regulator
FPL01_RS20325	COG2337	Toxic component of a toxin-antitoxin (TA) module
FPL01_RS20330	COG2183	response to ionizing radiation
FPL01_RS20425	COG0802	atpase or kinase
FPL01_RS20430	COG1214	PFAM Peptidase M22, glycoprotease
FPL01_RS20435	COG0456	acetyltransferase
FPL01_RS20445	COG0488	(ABC) transporter
FPL01_RS20460	COG1266	CAAX protease self-immunity
FPL01_RS20510	COG2946	Replication initiation factor
FPL01_RS20525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FPL01_RS20535	COG2252	PERMEase
FPL01_RS20545	COG5002	protein histidine kinase activity
FPL01_RS20570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FPL01_RS20600	COG2226	methyltransferase
FPL01_RS20620	COG1215	transferase activity, transferring glycosyl groups
FPL01_RS20645	COG0583	DNA-binding transcription factor activity
FPL01_RS20675	COG0697	spore germination
FPL01_RS20700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FPL01_RS20705	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FPL01_RS20710	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPL01_RS20720	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPL01_RS20735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FPL01_RS20745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPL01_RS20755	COG0151	Belongs to the GarS family
FPL01_RS20780	COG0210	DNA helicase
FPL01_RS20790	COG4851	CamS sex pheromone cAM373 precursor
FPL01_RS20805	COG1335	isochorismatase
FPL01_RS20815	COG2011	ABC-type metal ion transport system permease component
FPL01_RS20835	COG0003	Pfam Anion-transporting ATPase
FPL01_RS20840	COG1846	Transcriptional regulator
FPL01_RS20845	COG4682	membrane
FPL01_RS20865	COG1597	lipid kinase activity
FPL01_RS20870	COG0546	phosphoglycolate phosphatase activity
FPL01_RS20875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FPL01_RS20885	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS20890	COG2076	Multidrug Resistance protein
FPL01_RS20900	COG2309	aminopeptidase activity
FPL01_RS20910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS20915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPL01_RS20920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPL01_RS20935	COG4807	Protein conserved in bacteria
FPL01_RS20965	COG1473	amidohydrolase
FPL01_RS20985	COG0450	alkyl hydroperoxide reductase
FPL01_RS21010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS21015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS21020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL01_RS21035	COG0166	Belongs to the GPI family
FPL01_RS21075	COG3541	Predicted nucleotidyltransferase
FPL01_RS21080	COG2814	Major facilitator Superfamily
FPL01_RS21085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPL01_RS21085	COG0723	plastoquinol--plastocyanin reductase activity
FPL01_RS21095	COG0765	amino acid transport
FPL01_RS21100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL01_RS21110	COG0840	transmembrane signaling receptor activity
FPL01_RS21135	COG0549	Belongs to the carbamate kinase family
FPL01_RS21150	COG0277	FAD linked oxidase domain protein
FPL01_RS21155	COG0366	Alpha amylase catalytic
FPL01_RS21160	COG2190	(PTS) system
FPL01_RS21160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL01_RS21160	COG1263	PTS System
FPL01_RS21180	COG0515	serine threonine protein kinase
FPL01_RS21195	COG1132	(ABC) transporter
FPL01_RS21220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FPL01_RS21235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPL01_RS21245	COG1116	anion transmembrane transporter activity
FPL01_RS21255	COG0488	(ABC) transporter
FPL01_RS21305	COG2270	Major facilitator Superfamily
FPL01_RS21335	COG2310	stress, protein
FPL01_RS21340	COG2310	stress, protein
FPL01_RS21345	COG2310	stress, protein
FPL01_RS21350	COG0861	Integral membrane protein TerC family
FPL01_RS21360	COG3853	Toxic anion resistance protein (TelA)
FPL01_RS21375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPL01_RS21385	COG1295	ribonuclease BN
FPL01_RS21395	COG0697	spore germination
FPL01_RS21410	COG0681	Belongs to the peptidase S26 family
FPL01_RS21420	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS21435	COG3871	stress protein (general stress protein 26)
FPL01_RS21440	COG0387	Pfam Sodium calcium exchanger
FPL01_RS21450	COG0535	radical SAM domain protein
FPL01_RS21470	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPL01_RS21490	COG3829	transcription factor binding
FPL01_RS21500	COG0833	amino acid
FPL01_RS21505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPL01_RS21530	COG1263	PTS System
FPL01_RS21530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL01_RS21550	COG0463	Glycosyl transferase, family 2
FPL01_RS21560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FPL01_RS21560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPL01_RS21575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FPL01_RS21595	COG0402	S-adenosylhomocysteine deaminase activity
FPL01_RS21600	COG1090	epimerase
FPL01_RS21635	COG1194	a g-specific adenine glycosylase
FPL01_RS21660	COG1132	(ABC) transporter
FPL01_RS21665	COG4129	membrane
FPL01_RS21670	COG0070	glutamate synthase
FPL01_RS21670	COG0069	glutamate synthase activity
FPL01_RS21670	COG0067	glutamate synthase
FPL01_RS21680	COG4555	ABC transporter
FPL01_RS21700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FPL01_RS21705	COG0735	belongs to the Fur family
FPL01_RS21815	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FPL01_RS21820	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FPL01_RS21830	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPL01_RS21840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FPL01_RS21850	COG2766	serine protein kinase
FPL01_RS21870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FPL01_RS21880	COG1585	Membrane protein implicated in regulation of membrane protease activity
FPL01_RS21885	COG2268	Band 7 protein
FPL01_RS21895	COG3290	protein histidine kinase activity
FPL01_RS21900	COG4565	transcriptional regulatory protein
FPL01_RS21905	COG2851	Citrate transporter
FPL01_RS21930	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FPL01_RS21935	COG3842	ATPase activity
FPL01_RS21940	COG1175	transmembrane transport
FPL01_RS21945	COG0395	ABC-type sugar transport system, permease component
FPL01_RS21960	COG0745	RESPONSE REGULATOR receiver
FPL01_RS21965	COG5002	protein histidine kinase activity
FPL01_RS21975	COG4990	cell redox homeostasis
FPL01_RS21985	COG3290	protein histidine kinase activity
FPL01_RS21990	COG4565	transcriptional regulatory protein
FPL01_RS21995	COG3493	citrate carrier protein
FPL01_RS22000	COG0281	malic enzyme
FPL01_RS22010	COG0697	spore germination
FPL01_RS22015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPL01_RS22025	COG5002	protein histidine kinase activity
FPL01_RS22030	COG0745	RESPONSE REGULATOR receiver
FPL01_RS22035	COG0454	-acetyltransferase
FPL01_RS22035	COG0456	acetyltransferase
FPL01_RS22040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FPL01_RS22045	COG3383	formate dehydrogenase (NAD+) activity
FPL01_RS22050	COG2427	Protein of unknown function (DUF1641)
FPL01_RS22065	COG0531	amino acid
FPL01_RS22070	COG0640	Transcriptional regulator
FPL01_RS22075	COG2217	Heavy metal translocating P-type atpase
FPL01_RS22080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPL01_RS22095	COG3227	Zinc metalloprotease (Elastase)
FPL01_RS22115	COG2720	vancomycin resistance protein
FPL01_RS22120	COG1316	TRANSCRIPTIONal
FPL01_RS22125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FPL01_RS22130	COG0346	lactoylglutathione lyase activity
FPL01_RS22135	COG1253	flavin adenine dinucleotide binding
FPL01_RS22140	COG1027	Aspartate ammonia-lyase
FPL01_RS22145	COG1620	l-lactate permease
FPL01_RS22160	COG3104	oligopeptide transport
FPL01_RS22165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FPL01_RS22170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS22175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPL01_RS22185	COG2226	methyltransferase
FPL01_RS22190	COG0156	8-amino-7-oxononanoate synthase activity
FPL01_RS22195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FPL01_RS22200	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPL01_RS22210	COG4548	von Willebrand factor, type A
FPL01_RS22215	COG0714	Associated with various cellular activities
FPL01_RS22240	COG0531	amino acid
FPL01_RS22245	COG2188	Transcriptional regulator
FPL01_RS22250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL01_RS22250	COG1263	PTS System
FPL01_RS22270	COG0697	spore germination
FPL01_RS22280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FPL01_RS22285	COG1115	amino acid carrier protein
FPL01_RS22290	COG1126	abc transporter atp-binding protein
FPL01_RS22295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL01_RS22300	COG0765	amino acid transport
FPL01_RS22305	COG0765	amino acid transport
FPL01_RS22310	COG0833	amino acid
FPL01_RS22325	COG1595	DNA-templated transcription, initiation
FPL01_RS22345	COG5002	protein histidine kinase activity
FPL01_RS22380	COG0747	negative chemotaxis
FPL01_RS22390	COG0601	transmembrane transport
FPL01_RS22395	COG4608	Belongs to the ABC transporter superfamily
FPL01_RS22405	COG2271	Major facilitator Superfamily
FPL01_RS22410	COG1846	Transcriptional regulator
FPL01_RS22415	COG0477	Major facilitator Superfamily
FPL01_RS22420	COG1609	Transcriptional regulator
FPL01_RS22425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPL01_RS22440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FPL01_RS22445	COG1879	ABC-type sugar transport system periplasmic component
FPL01_RS22465	COG1063	alcohol dehydrogenase
FPL01_RS22480	COG3568	Endonuclease Exonuclease Phosphatase
FPL01_RS22510	COG0840	transmembrane signaling receptor activity
FPL01_RS22515	COG3584	3D domain protein
FPL01_RS22515	COG3583	domain protein
FPL01_RS22520	COG1476	TRANSCRIPTIONal
FPL01_RS22535	COG3104	oligopeptide transport
FPL01_RS22540	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS22555	COG1113	amino acid transport
FPL01_RS22560	COG2252	PERMEase
FPL01_RS22585	COG0475	glutathione-regulated potassium exporter activity
FPL01_RS22585	COG0569	domain protein
FPL01_RS22600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPL01_RS22605	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPL01_RS22610	COG0833	amino acid
FPL01_RS22615	COG4990	cell redox homeostasis
FPL01_RS22630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPL01_RS22635	COG0697	spore germination
FPL01_RS22640	COG0531	amino acid
FPL01_RS22650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPL01_RS22655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPL01_RS22660	COG1918	ferrous iron import across plasma membrane
FPL01_RS22660	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FPL01_RS22665	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FPL01_RS22670	COG0573	inorganic phosphate transmembrane transporter activity
FPL01_RS22675	COG0581	inorganic phosphate transmembrane transporter activity
FPL01_RS22685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FPL01_RS22805	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
FPL01_RS22825	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FPL01_RS22830	COG1116	anion transmembrane transporter activity
FPL01_RS22835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPL01_RS22840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPL01_RS22845	COG0352	thiamine-phosphate diphosphorylase activity
FPL01_RS22850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPL01_RS22855	COG2104	thiamine diphosphate biosynthetic process
FPL01_RS22865	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPL01_RS22870	COG0351	phosphomethylpyrimidine kinase
FPL01_RS22910	COG2205	protein histidine kinase activity
FPL01_RS22915	COG2814	Major facilitator Superfamily
FPL01_RS22920	COG1846	Transcriptional regulator
FPL01_RS22935	COG2252	PERMEase
FPL01_RS22940	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS22960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPL01_RS23000	COG0778	Nitroreductase
FPL01_RS23005	COG2719	SpoVR family
FPL01_RS23015	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPL01_RS23020	COG1937	Protein conserved in bacteria
FPL01_RS23025	COG0425	Belongs to the sulfur carrier protein TusA family
FPL01_RS23025	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL01_RS23030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPL01_RS23030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL01_RS23035	COG0425	Belongs to the sulfur carrier protein TusA family
FPL01_RS23040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPL01_RS23050	COG2210	Belongs to the sulfur carrier protein TusA family
FPL01_RS23055	COG0730	response to heat
FPL01_RS23065	COG1316	TRANSCRIPTIONal
FPL01_RS23110	COG1447	Phosphotransferase system cellobiose-specific component IIA
FPL01_RS23115	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FPL01_RS23135	COG3584	3D domain protein
FPL01_RS23135	COG1388	LysM domain
FPL01_RS23140	COG0577	efflux transmembrane transporter activity
FPL01_RS23145	COG1136	(ABC) transporter
FPL01_RS23155	COG5522	Integral membrane protein (intg_mem_TP0381)
FPL01_RS23170	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS23175	COG3546	catalase activity
FPL01_RS23210	COG0586	Pfam SNARE associated Golgi protein
FPL01_RS23240	COG0531	amino acid
FPL01_RS23245	COG0475	glutathione-regulated potassium exporter activity
FPL01_RS23255	COG1737	Transcriptional regulator
FPL01_RS23265	COG1263	PTS System
FPL01_RS23265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FPL01_RS23275	COG2259	Doxx family
FPL01_RS23295	COG1522	sequence-specific DNA binding
FPL01_RS23320	COG2076	Multidrug Resistance protein
FPL01_RS23325	COG1309	transcriptional regulator
FPL01_RS23330	COG2814	Major facilitator Superfamily
FPL01_RS23360	COG1136	(ABC) transporter
FPL01_RS23365	COG0577	efflux transmembrane transporter activity
FPL01_RS23370	COG1136	(ABC) transporter
FPL01_RS23375	COG0577	efflux transmembrane transporter activity
FPL01_RS23390	COG1733	regulation of RNA biosynthetic process
FPL01_RS23400	COG2249	NAD(P)H dehydrogenase (quinone) activity
FPL01_RS23410	COG2211	Major facilitator Superfamily
FPL01_RS23420	COG0693	protein deglycase activity
FPL01_RS23425	COG0753	catalase activity
FPL01_RS23425	COG0693	protein deglycase activity
FPL01_RS23435	COG0531	amino acid
FPL01_RS23440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FPL01_RS23445	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS23455	COG1132	(ABC) transporter
FPL01_RS23460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPL01_RS23465	COG0765	amino acid transport
FPL01_RS23470	COG1126	abc transporter atp-binding protein
FPL01_RS23485	COG0189	ligase activity
FPL01_RS23515	COG0028	Belongs to the TPP enzyme family
FPL01_RS23520	COG3527	Alpha-acetolactate decarboxylase
FPL01_RS23535	COG0561	phosphatase activity
FPL01_RS23550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPL01_RS23570	COG0659	secondary active sulfate transmembrane transporter activity
FPL01_RS23600	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPL01_RS23605	COG4196	transglutaminase domain protein
FPL01_RS23620	COG1696	Membrane protein involved in D-alanine export
FPL01_RS23635	COG1024	Enoyl-CoA hydratase
FPL01_RS23650	COG1363	Peptidase, m42
FPL01_RS23695	COG0601	transmembrane transport
FPL01_RS23700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPL01_RS23705	COG0444	Belongs to the ABC transporter superfamily
FPL01_RS23710	COG4608	Belongs to the ABC transporter superfamily
FPL01_RS23730	COG0477	Major facilitator Superfamily
FPL01_RS23735	COG3290	protein histidine kinase activity
FPL01_RS23740	COG4565	transcriptional regulatory protein
FPL01_RS23805	COG1074	ATP-dependent DNA helicase activity
FPL01_RS23830	COG0305	Participates in initiation and elongation during chromosome replication
FPL01_RS23895	COG3711	transcriptional antiterminator
FPL01_RS23915	COG1183	phosphatidylcholine synthase activity
FPL01_RS23940	COG2376	Dihydroxyacetone kinase
FPL01_RS23950	COG2376	Dihydroxyacetone kinase
FPL01_RS24065	COG1191	sigma factor activity
FPL01_RS24075	COG2208	phosphoserine phosphatase activity
FPL01_RS24080	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FPL01_RS24130	COG2814	Major facilitator Superfamily
FPL01_RS24160	COG0420	3'-5' exonuclease activity
FPL01_RS24185	COG0346	lactoylglutathione lyase activity
FPL01_RS24190	COG0457	Tetratricopeptide repeat
FPL01_RS24200	COG2267	carboxylic ester hydrolase activity
FPL01_RS24210	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FPL01_RS24215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FPL01_RS24225	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FPL01_RS24255	COG3973	AAA domain
FPL01_RS24320	COG0464	growth
FPL01_RS24325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPL01_RS24345	COG4980	gas vesicle protein
FPL01_RS24350	COG0537	adenosine 5'-monophosphoramidase activity
FPL01_RS24355	COG1131	(ABC) transporter
FPL01_RS24360	COG4473	ABC transporter
FPL01_RS24375	COG1309	transcriptional regulator
FPL01_RS24380	COG3402	PFAM membrane-flanked domain
FPL01_RS24385	COG3428	Bacterial PH domain
FPL01_RS24405	COG3402	PFAM membrane-flanked domain
FPL01_RS24410	COG3428	Bacterial PH domain
FPL01_RS24415	COG2329	Antibiotic biosynthesis monooxygenase
FPL01_RS24420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FPL01_RS24470	COG1309	transcriptional regulator
FPL01_RS24475	COG1511	domain protein
FPL01_RS24500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FPL01_RS24505	COG2318	DinB family
FPL01_RS24510	COG2378	regulation of single-species biofilm formation
FPL01_RS24515	COG1609	Transcriptional regulator
FPL01_RS24525	COG1234	tRNA 3'-trailer cleavage
FPL01_RS24530	COG0095	Lipoate-protein ligase
FPL01_RS24540	COG0318	PFAM AMP-dependent synthetase and ligase
FPL01_RS24545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FPL01_RS24555	COG4208	sulfate ABC transporter
FPL01_RS24565	COG3209	COG3209 Rhs family protein
FPL01_RS24620	COG1073	alpha beta
FPL01_RS24630	COG1078	dGTPase activity
FPL01_RS24640	COG0477	Major facilitator Superfamily
FPL01_RS24655	COG2207	Transcriptional regulator
FPL01_RS24655	COG3708	Transcriptional regulator
FPL01_RS24660	COG2205	protein histidine kinase activity
FPL01_RS24665	COG0745	RESPONSE REGULATOR receiver
FPL01_RS24685	COG0501	Belongs to the peptidase M48B family
FPL01_RS24690	COG0697	spore germination
FPL01_RS24710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPL01_RS24715	COG2224	Isocitrate lyase
FPL01_RS24765	COG0398	Pfam SNARE associated Golgi protein
FPL01_RS24850	COG0367	asparagine synthase
FPL01_RS24860	COG0753	catalase activity
FPL01_RS24870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPL01_RS24890	COG3339	Conserved Protein
FPL01_RS24895	COG0004	ammonium transporteR
FPL01_RS24915	COG2996	Protein conserved in bacteria
FPL01_RS24920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPL01_RS24930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS24945	COG0561	phosphatase activity
FPL01_RS24970	COG2267	carboxylic ester hydrolase activity
FPL01_RS24985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPL01_RS24990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPL01_RS24995	COG5504	Zn-dependent protease
FPL01_RS25005	COG0180	Tryptophanyl-tRNA synthetase
FPL01_RS25015	COG4166	transmembrane transport
FPL01_RS25020	COG0601	transmembrane transport
FPL01_RS25025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPL01_RS25030	COG0444	Belongs to the ABC transporter superfamily
FPL01_RS25035	COG4608	Belongs to the ABC transporter superfamily
FPL01_RS25040	COG0534	Mate efflux family protein
FPL01_RS25045	COG4166	transmembrane transport
FPL01_RS25060	COG0861	Integral membrane protein TerC family
FPL01_RS25065	COG4862	establishment of competence for transformation
FPL01_RS25070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPL01_RS25080	COG1164	Oligoendopeptidase f
FPL01_RS25090	COG2346	COG2346, Truncated hemoglobins
FPL01_RS25095	COG4116	CYTH
FPL01_RS25105	COG2357	RelA SpoT domain protein
FPL01_RS25115	COG0564	pseudouridine synthase activity
FPL01_RS25130	COG0772	Belongs to the SEDS family
FPL01_RS25135	COG1216	Glycosyl transferase, family 2
FPL01_RS25155	COG0463	Glycosyl transferase, family 2
FPL01_RS25155	COG0457	Tetratricopeptide repeat
FPL01_RS25175	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FPL01_RS25190	COG1091	dTDP-4-dehydrorhamnose reductase activity
FPL01_RS25235	COG2153	protein acetylation
FPL01_RS25245	COG2382	esterase
FPL01_RS25270	COG5492	domain, Protein
FPL01_RS25275	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPL01_RS25285	COG0512	Glutamine amidotransferase of anthranilate synthase
FPL01_RS25285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FPL01_RS25320	COG1620	l-lactate permease
FPL01_RS25325	COG5634	Uncharacterized conserved protein (DUF2278)
FPL01_RS25365	COG2226	methyltransferase
FPL01_RS25385	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPL01_RS25395	COG1476	TRANSCRIPTIONal
FPL01_RS25480	COG0582	viral genome integration into host DNA
FPL01_RS25505	COG1686	Belongs to the peptidase S11 family
FPL01_RS25510	COG0681	Belongs to the peptidase S26 family
FPL01_RS25530	COG1396	sequence-specific DNA binding
FPL01_RS25545	COG1012	belongs to the aldehyde dehydrogenase family
FPL01_RS25555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPL01_RS25560	COG1177	transmembrane transport
FPL01_RS25565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FPL01_RS25575	COG2409	Drug exporters of the RND superfamily
FPL01_RS25585	COG0564	pseudouridine synthase activity
FPL01_RS25600	COG0247	lactate metabolic process
FPL01_RS25605	COG0277	FAD linked oxidase domain protein
FPL01_RS25610	COG3835	regulator
FPL01_RS25620	COG0745	RESPONSE REGULATOR receiver
FPL01_RS25625	COG5002	protein histidine kinase activity
FPL01_RS25630	COG2186	Transcriptional regulator
FPL01_RS25650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FPL01_RS25660	COG2116	formate transmembrane transporter activity
FPL01_RS25665	COG0861	Integral membrane protein TerC family
FPL01_RS25670	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPL01_RS25700	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS25705	COG3243	poly(R)-hydroxyalkanoic acid synthase
FPL01_RS25715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPL01_RS25725	COG1840	ABC-type Fe3 transport system, periplasmic component
FPL01_RS25755	COG1349	DNA-binding transcription factor activity
FPL01_RS25765	COG0235	Class ii aldolase
FPL01_RS25785	COG3852	Histidine kinase
FPL01_RS25790	COG1846	Transcriptional regulator
FPL01_RS25805	COG5002	protein histidine kinase activity
FPL01_RS25815	COG0720	synthase
FPL01_RS25830	COG4873	Protein conserved in bacteria
FPL01_RS25860	COG1780	Probably involved in ribonucleotide reductase function
FPL01_RS25880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FPL01_RS25885	COG1725	Transcriptional regulator
FPL01_RS25890	COG1131	(ABC) transporter
FPL01_RS25900	COG1131	(ABC) transporter
FPL01_RS25905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
FPL01_RS25910	COG1266	CAAX protease self-immunity
FPL01_RS25920	COG1522	sequence-specific DNA binding
FPL01_RS25930	COG1335	isochorismatase
FPL01_RS25940	COG1619	proteins homologs of microcin C7 resistance protein MccF
FPL01_RS25945	COG2070	2-Nitropropane dioxygenase
FPL01_RS25950	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FPL01_RS25960	COG1696	Membrane protein involved in D-alanine export
FPL01_RS25985	COG0716	FMN binding
FPL01_RS26045	COG1301	dicarboxylic acid transport
FPL01_RS26050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPL01_RS26055	COG4709	membrane
FPL01_RS26060	COG3874	Sporulation protein YtfJ
FPL01_RS26080	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FPL01_RS26085	COG0028	Belongs to the TPP enzyme family
FPL01_RS26090	COG0440	acetolactate synthase activity
FPL01_RS26165	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPL01_RS26180	COG1183	phosphatidylcholine synthase activity
FPL01_RS26185	COG1368	sulfuric ester hydrolase activity
FPL01_RS26195	COG0019	diaminopimelate decarboxylase activity
FPL01_RS26215	COG0529	Catalyzes the synthesis of activated sulfate
FPL01_RS26220	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPL01_RS26240	COG1648	precorrin-2 dehydrogenase activity
FPL01_RS26245	COG0733	neurotransmitter:sodium symporter activity
FPL01_RS26265	COG1757	Na H antiporter
FPL01_RS26280	COG4758	membrane
FPL01_RS26285	COG4585	Histidine kinase
FPL01_RS26290	COG2197	response regulator
FPL01_RS26300	COG1114	Component of the transport system for branched-chain amino acids
FPL01_RS26310	COG2226	methyltransferase
FPL01_RS26345	COG0730	response to heat
FPL01_RS26350	COG0306	phosphate transporter
FPL01_RS26355	COG1392	Phosphate transport regulator
FPL01_RS26380	COG3852	Histidine kinase
FPL01_RS26385	COG1801	Protein of unknown function DUF72
FPL01_RS26395	COG0582	viral genome integration into host DNA
FPL01_RS26400	COG5002	protein histidine kinase activity
FPL01_RS26420	COG0392	lysyltransferase activity
FPL01_RS26420	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FPL01_RS26435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPL01_RS26440	COG1686	Belongs to the peptidase S11 family
FPL01_RS26445	COG2715	membrane protein required for spore maturation
FPL01_RS26450	COG0700	Nucleoside recognition
FPL01_RS26455	COG1187	pseudouridine synthase activity
FPL01_RS26465	COG1333	cytochrome c biogenesis protein
FPL01_RS26470	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPL01_RS26475	COG0745	RESPONSE REGULATOR receiver
FPL01_RS26480	COG5002	protein histidine kinase activity
FPL01_RS26485	COG2096	Adenosyltransferase
FPL01_RS26490	COG4942	peptidase
FPL01_RS26500	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FPL01_RS26505	COG1141	Ferredoxin
FPL01_RS26515	COG0514	ATP-dependent DNA helicase (RecQ)
FPL01_RS26530	COG1408	metallophosphoesterase
FPL01_RS26540	COG4862	establishment of competence for transformation
FPL01_RS26545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPL01_RS26565	COG0492	ferredoxin-NADP+ reductase activity
FPL01_RS26640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPL01_RS26655	COG0142	geranyltranstransferase activity
FPL01_RS26665	COG0142	geranyltranstransferase activity
FPL01_RS26690	COG0457	Tetratricopeptide repeat
FPL01_RS26710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FPL01_RS26715	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FPL01_RS26715	COG2010	Cytochrome c
FPL01_RS26720	COG4347	Protein of unknown function (DUF1405)
FPL01_RS26735	COG2738	Putative neutral zinc metallopeptidase
FPL01_RS26745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FPL01_RS26750	COG1694	Mazg nucleotide pyrophosphohydrolase
FPL01_RS26765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPL01_RS26770	COG0438	transferase activity, transferring glycosyl groups
FPL01_RS26805	COG1199	ATP-dependent helicase activity
FPL01_RS26805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPL01_RS26825	COG3935	DnaD domain protein
FPL01_RS26830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FPL01_RS26895	COG0116	Belongs to the methyltransferase superfamily
FPL01_RS26905	COG1199	ATP-dependent helicase activity
FPL01_RS26920	COG0024	Methionine aminopeptidase
FPL01_RS26930	COG2233	PERMEase
FPL01_RS26935	COG2311	Membrane
FPL01_RS26940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FPL01_RS26950	COG0456	acetyltransferase
FPL01_RS26980	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPL01_RS26995	COG0454	-acetyltransferase
FPL01_RS27050	COG3403	YqcI/YcgG family
FPL01_RS27055	COG1280	lysine exporter protein (LysE YggA)
FPL01_RS27070	COG3162	membrane
FPL01_RS27075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPL01_RS27080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FPL01_RS27090	COG0475	glutathione-regulated potassium exporter activity
FPL01_RS27095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPL01_RS27100	COG4978	Transcriptional regulator
FPL01_RS27100	COG0789	Transcriptional regulator
FPL01_RS27110	COG2323	membrane
FPL01_RS27115	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FPL01_RS27145	COG2814	Major facilitator Superfamily
FPL01_RS27155	COG2814	Major facilitator Superfamily
FPL01_RS27175	COG1923	regulation of RNA biosynthetic process
FPL01_RS27185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FPL01_RS27190	COG1360	Flagellar Motor Protein
FPL01_RS27195	COG2201	protein-glutamate methylesterase activity
FPL01_RS27200	COG0643	Histidine kinase
FPL01_RS27200	COG2198	Histidine kinase
FPL01_RS27205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPL01_RS27205	COG1776	CheC inhibitor of MCP methylation
FPL01_RS27220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FPL01_RS27240	COG1256	bacterial-type flagellum assembly
FPL01_RS27245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPL01_RS27250	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FPL01_RS27265	COG1815	bacterial-type flagellum-dependent cell motility
FPL01_RS27270	COG1558	bacterial-type flagellum-dependent cell motility
FPL01_RS27280	COG1766	The M ring may be actively involved in energy transduction
FPL01_RS27285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPL01_RS27295	COG1157	protein secretion by the type III secretion system
FPL01_RS27340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPL01_RS27345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FPL01_RS27350	COG0741	lytic transglycosylase activity
FPL01_RS27360	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPL01_RS27365	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FPL01_RS27365	COG1776	CheC inhibitor of MCP methylation
FPL01_RS27375	COG1338	Plays a role in the flagellum-specific transport system
FPL01_RS27380	COG1987	bacterial-type flagellum assembly
FPL01_RS27390	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPL01_RS27395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FPL01_RS27405	COG4786	Flagellar basal body rod
FPL01_RS27410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPL01_RS27435	COG1309	transcriptional regulator
FPL01_RS27455	COG2329	Antibiotic biosynthesis monooxygenase
FPL01_RS27470	COG3764	Sortase (surface protein transpeptidase)
FPL01_RS27475	COG3764	Sortase (surface protein transpeptidase)
FPL01_RS27500	COG0583	DNA-binding transcription factor activity
FPL01_RS27505	COG3842	ATPase activity
FPL01_RS27520	COG1234	tRNA 3'-trailer cleavage
FPL01_RS27535	COG1028	Short-chain dehydrogenase reductase Sdr
FPL01_RS27580	COG1846	Transcriptional regulator
FPL01_RS27625	COG1802	Transcriptional regulator
FPL01_RS27630	COG0697	spore germination
FPL01_RS27635	COG0523	cobalamin synthesis protein
FPL01_RS27650	COG0438	transferase activity, transferring glycosyl groups
FPL01_RS27650	COG1216	Glycosyl transferase, family 2
FPL01_RS27655	COG1757	Na H antiporter
FPL01_RS27660	COG0114	fumarate hydratase activity
FPL01_RS27675	COG0534	Mate efflux family protein
FPL01_RS27680	COG3340	Belongs to the peptidase S51 family
FPL01_RS27755	COG1131	(ABC) transporter