locus-tag	class	description
OU809_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OU809_RS00010	COG0592	DNA-directed DNA polymerase activity
OU809_RS00015	COG2501	S4 domain
OU809_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OU809_RS00030	COG0187	DNA topoisomerase II activity
OU809_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OU809_RS00070	COG0516	GMP reductase activity
OU809_RS00070	COG0517	IMP dehydrogenase activity
OU809_RS00075	COG1686	Belongs to the peptidase S11 family
OU809_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OU809_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OU809_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OU809_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
OU809_RS00100	COG2610	gluconate transmembrane transporter activity
OU809_RS00105	COG3835	regulator
OU809_RS00120	COG1428	Deoxynucleoside kinase
OU809_RS00125	COG1428	Deoxynucleoside kinase
OU809_RS00130	COG1388	LysM domain
OU809_RS00130	COG3858	chitin binding
OU809_RS00135	COG1335	isochorismatase
OU809_RS00140	COG0590	tRNA wobble adenosine to inosine editing
OU809_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OU809_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OU809_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OU809_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OU809_RS00210	COG3853	Toxic anion resistance protein (TelA)
OU809_RS00215	COG1982	Orn Lys Arg decarboxylase major
OU809_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OU809_RS00225	COG3870	Protein conserved in bacteria
OU809_RS00230	COG1728	Protein conserved in bacteria
OU809_RS00235	COG0470	DNA polymerase III
OU809_RS00240	COG1774	PSP1 C-terminal conserved region
OU809_RS00245	COG4467	Involved in initiation control of chromosome replication
OU809_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OU809_RS00255	COG2827	Endonuclease containing a URI domain
OU809_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OU809_RS00265	COG2002	toxin-antitoxin pair type II binding
OU809_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU809_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU809_RS00275	COG0084	hydrolase, TatD family'
OU809_RS00280	COG3583	domain protein
OU809_RS00280	COG3584	3D domain protein
OU809_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OU809_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OU809_RS00300	COG4466	Protein conserved in bacteria
OU809_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OU809_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OU809_RS00320	COG0251	oxidation-reduction process
OU809_RS00325	COG2088	sporulation resulting in formation of a cellular spore
OU809_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OU809_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OU809_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OU809_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
OU809_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OU809_RS00360	COG2002	toxin-antitoxin pair type II binding
OU809_RS00365	COG2244	polysaccharide biosynthetic process
OU809_RS00370	COG3956	TIGRFAM MazG family protein
OU809_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OU809_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OU809_RS00395	COG1098	S1 RNA binding domain
OU809_RS00410	COG2208	phosphoserine phosphatase activity
OU809_RS00415	COG2304	oxidoreductase activity
OU809_RS00420	COG0515	serine threonine protein kinase
OU809_RS00425	COG0037	tRNA processing
OU809_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OU809_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OU809_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OU809_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OU809_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OU809_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU809_RS00460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OU809_RS00465	COG0512	Glutamine amidotransferase of anthranilate synthase
OU809_RS00470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU809_RS00475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OU809_RS00480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OU809_RS00485	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OU809_RS00490	COG1396	sequence-specific DNA binding
OU809_RS00495	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OU809_RS00500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OU809_RS00580	COG4463	regulation of RNA biosynthetic process
OU809_RS00585	COG3880	PFAM UvrB UvrC protein
OU809_RS00590	COG3869	Catalyzes the specific phosphorylation of arginine residues in
OU809_RS00595	COG0542	response to heat
OU809_RS00600	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OU809_RS00605	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OU809_RS00610	COG4956	integral membrane protein (PIN domain superfamily)
OU809_RS00615	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OU809_RS00620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OU809_RS00625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OU809_RS00630	COG1045	serine acetyltransferase
OU809_RS00635	COG0215	cysteine-tRNA ligase activity
OU809_RS00645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OU809_RS00650	COG3688	RNA-binding protein containing a PIN domain
OU809_RS00670	COG0250	Participates in transcription elongation, termination and antitermination
OU809_RS00675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OU809_RS00680	COG0081	regulation of translation
OU809_RS00685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OU809_RS00690	COG0222	ribosome binding
OU809_RS00695	COG2813	Specifically methylates the guanine in position
OU809_RS00700	COG0085	RNA polymerase activity
OU809_RS00705	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OU809_RS00710	COG1358	cellular component organization or biogenesis
OU809_RS00715	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OU809_RS00720	COG0049	tRNA binding
OU809_RS00725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OU809_RS00730	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OU809_RS00740	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OU809_RS00745	COG0088	Forms part of the polypeptide exit tunnel
OU809_RS00750	COG0089	rRNA binding
OU809_RS00760	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OU809_RS00765	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OU809_RS00770	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OU809_RS00775	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OU809_RS00780	COG0255	Belongs to the universal ribosomal protein uL29 family
OU809_RS00785	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OU809_RS00790	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OU809_RS00795	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OU809_RS00800	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OU809_RS00805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OU809_RS00810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OU809_RS00815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OU809_RS00820	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OU809_RS00825	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OU809_RS00830	COG1841	ribosomal large subunit assembly
OU809_RS00835	COG0200	Binds to the 23S rRNA
OU809_RS00840	COG0201	protein transport
OU809_RS00845	COG0563	adenylate kinase activity
OU809_RS00850	COG0024	Methionine aminopeptidase
OU809_RS00855	COG2163	COG2163 Ribosomal protein L14E L6E L27E
OU809_RS00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OU809_RS00865	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OU809_RS00870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OU809_RS00875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OU809_RS00880	COG0202	RNA polymerase activity
OU809_RS00885	COG0203	ribosomal protein L17
OU809_RS00890	COG1122	ATPase activity
OU809_RS00895	COG1122	ATPase activity
OU809_RS00900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OU809_RS00905	COG0101	tRNA pseudouridine synthase activity
OU809_RS00910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OU809_RS00915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OU809_RS00920	COG2318	DinB family
OU809_RS00935	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU809_RS00940	COG0489	protein tyrosine kinase activity
OU809_RS00950	COG2194	sulfuric ester hydrolase activity
OU809_RS00955	COG0726	polysaccharide deacetylase
OU809_RS00985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU809_RS00995	COG0385	Bile acid
OU809_RS01010	COG3876	Protein conserved in bacteria
OU809_RS01015	COG1472	Belongs to the glycosyl hydrolase 3 family
OU809_RS01020	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU809_RS01025	COG1263	PTS System
OU809_RS01025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS01030	COG1737	Transcriptional regulator
OU809_RS01035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OU809_RS01040	COG1683	Conserved Protein
OU809_RS01075	COG1595	DNA-templated transcription, initiation
OU809_RS01080	COG5662	AntiSigma factor
OU809_RS01085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OU809_RS01090	COG4856	YbbR-like protein
OU809_RS01095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OU809_RS01100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OU809_RS01120	COG1725	Transcriptional regulator
OU809_RS01130	COG0789	Transcriptional regulator
OU809_RS01140	COG0640	Transcriptional regulator
OU809_RS01145	COG2814	Major facilitator Superfamily
OU809_RS01160	COG1131	(ABC) transporter
OU809_RS01180	COG1132	(ABC) transporter
OU809_RS01185	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OU809_RS01195	COG2312	Erythromycin esterase
OU809_RS01215	COG1011	Hydrolase
OU809_RS01235	COG2211	Major facilitator Superfamily
OU809_RS01255	COG1331	Highly conserved protein containing a thioredoxin domain
OU809_RS01260	COG1331	Highly conserved protein containing a thioredoxin domain
OU809_RS01265	COG2226	methyltransferase
OU809_RS01270	COG0076	glutamate decarboxylase activity
OU809_RS01275	COG0778	Nitroreductase
OU809_RS01280	COG1802	Transcriptional regulator
OU809_RS01285	COG0730	response to heat
OU809_RS01300	COG1283	sodium-dependent phosphate transmembrane transporter activity
OU809_RS01305	COG4682	membrane
OU809_RS01315	COG3409	Peptidoglycan-binding domain 1 protein
OU809_RS01325	COG0697	spore germination
OU809_RS01330	COG2207	Transcriptional regulator
OU809_RS01330	COG1917	Cupin 2, conserved barrel domain protein
OU809_RS01355	COG0371	Dehydrogenase
OU809_RS01370	COG4257	antibiotic catabolic process
OU809_RS01380	COG0833	amino acid
OU809_RS01385	COG2040	homocysteine
OU809_RS01395	COG1263	PTS System
OU809_RS01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS01400	COG0789	Transcriptional regulator
OU809_RS01405	COG2323	membrane
OU809_RS01410	COG4451	ribulose bisphosphate carboxylase, small
OU809_RS01410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OU809_RS01420	COG2205	protein histidine kinase activity
OU809_RS01425	COG1115	amino acid carrier protein
OU809_RS01430	COG2066	Belongs to the glutaminase family
OU809_RS01435	COG4191	Histidine kinase
OU809_RS01440	COG0784	Response regulator, receiver
OU809_RS01465	COG3540	Alkaline phosphatase
OU809_RS01470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OU809_RS01475	COG0805	protein transport
OU809_RS01480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OU809_RS01485	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS01490	COG2271	Major facilitator Superfamily
OU809_RS01495	COG4948	Mandelate Racemase Muconate Lactonizing
OU809_RS01500	COG2186	Transcriptional regulator
OU809_RS01505	COG2721	sulfolactate sulfo-lyase activity
OU809_RS01525	COG0745	RESPONSE REGULATOR receiver
OU809_RS01530	COG2205	protein histidine kinase activity
OU809_RS01535	COG1131	(ABC) transporter
OU809_RS01560	COG3173	Aminoglycoside phosphotransferase
OU809_RS01565	COG1846	Transcriptional regulator
OU809_RS01570	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS01590	COG0789	Transcriptional regulator
OU809_RS01615	COG0697	spore germination
OU809_RS01625	COG1714	RDD family
OU809_RS01630	COG3012	SEC-C Motif Domain Protein
OU809_RS01630	COG1405	negative regulation of cell septum assembly
OU809_RS01635	COG1131	(ABC) transporter
OU809_RS01660	COG0583	DNA-binding transcription factor activity
OU809_RS01665	COG1942	4-Oxalocrotonate Tautomerase
OU809_RS01670	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS01685	COG1288	antiporter activity
OU809_RS01695	COG0252	asparaginase activity
OU809_RS01700	COG0456	acetyltransferase
OU809_RS01710	COG1164	Oligoendopeptidase f
OU809_RS01715	COG2261	transglycosylase associated protein
OU809_RS01725	COG0247	lactate metabolic process
OU809_RS01730	COG0277	FAD linked oxidase domain protein
OU809_RS01735	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS01740	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU809_RS01745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS01750	COG1486	melibiose metabolic process
OU809_RS01755	COG2188	Transcriptional regulator
OU809_RS01760	COG3394	polysaccharide catabolic process
OU809_RS01775	COG3591	Belongs to the peptidase S1B family
OU809_RS01780	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS01790	COG1595	DNA-templated transcription, initiation
OU809_RS01800	COG3773	Cell wall hydrolase
OU809_RS01805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU809_RS01810	COG3883	PFAM NLP P60 protein
OU809_RS01810	COG0791	NLP P60 protein
OU809_RS01820	COG1131	(ABC) transporter
OU809_RS01825	COG1309	transcriptional regulator
OU809_RS01845	COG2310	stress, protein
OU809_RS01850	COG2310	stress, protein
OU809_RS01855	COG2310	stress, protein
OU809_RS01860	COG0861	Integral membrane protein TerC family
OU809_RS01880	COG3853	Toxic anion resistance protein (TelA)
OU809_RS01885	COG0785	Cytochrome C biogenesis protein
OU809_RS01895	COG2223	nitrite transmembrane transporter activity
OU809_RS01900	COG0039	L-malate dehydrogenase activity
OU809_RS01905	COG1620	l-lactate permease
OU809_RS01910	COG1280	lysine exporter protein (LysE YggA)
OU809_RS01915	COG1113	amino acid transport
OU809_RS01920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OU809_RS01925	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OU809_RS01930	COG3541	Predicted nucleotidyltransferase
OU809_RS01935	COG0506	proline dehydrogenase activity
OU809_RS01940	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS01945	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS01950	COG2508	Transcriptional regulator
OU809_RS01955	COG3689	TIGRFAM TIGR03943 family protein
OU809_RS01960	COG0701	Predicted permease
OU809_RS01965	COG3458	cephalosporin-C deacetylase activity
OU809_RS01985	COG0765	amino acid transport
OU809_RS01990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU809_RS01995	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU809_RS02000	COG1116	anion transmembrane transporter activity
OU809_RS02005	COG2723	6-phospho-beta-galactosidase activity
OU809_RS02015	COG3209	COG3209 Rhs family protein
OU809_RS02030	COG5444	nuclease activity
OU809_RS02060	COG1177	transmembrane transport
OU809_RS02065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS02070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS02075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS02080	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OU809_RS02085	COG0697	spore germination
OU809_RS02090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS02100	COG2819	hydrolase of the alpha beta superfamily
OU809_RS02110	COG2364	Membrane
OU809_RS02135	COG1126	abc transporter atp-binding protein
OU809_RS02140	COG0765	amino acid transport
OU809_RS02145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU809_RS02150	COG3829	transcription factor binding
OU809_RS02155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OU809_RS02160	COG0833	amino acid
OU809_RS02165	COG0010	Belongs to the arginase family
OU809_RS02170	COG0583	DNA-binding transcription factor activity
OU809_RS02175	COG0163	prenyltransferase activity
OU809_RS02180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OU809_RS02245	COG5444	nuclease activity
OU809_RS02265	COG2972	Histidine kinase
OU809_RS02270	COG2207	Transcriptional regulator
OU809_RS02270	COG4753	response regulator
OU809_RS02275	COG4213	ABC transporter substrate-binding protein
OU809_RS02285	COG4214	carbohydrate transport
OU809_RS02290	COG2271	Major facilitator Superfamily
OU809_RS02295	COG0456	acetyltransferase
OU809_RS02295	COG1846	Transcriptional regulator
OU809_RS02300	COG1874	Beta-galactosidase
OU809_RS02310	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
OU809_RS02320	COG3104	oligopeptide transport
OU809_RS02325	COG5434	Belongs to the glycosyl hydrolase 28 family
OU809_RS02335	COG0697	spore germination
OU809_RS02345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OU809_RS02350	COG0789	Transcriptional regulator
OU809_RS02355	COG1136	(ABC) transporter
OU809_RS02360	COG0577	efflux transmembrane transporter activity
OU809_RS02365	COG0745	RESPONSE REGULATOR receiver
OU809_RS02370	COG5002	protein histidine kinase activity
OU809_RS02370	COG3850	Histidine kinase
OU809_RS02375	COG0840	transmembrane signaling receptor activity
OU809_RS02380	COG0527	aspartate kinase activity
OU809_RS02385	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS02390	COG4605	iron ion homeostasis
OU809_RS02395	COG4604	ABC transporter, ATP-binding protein
OU809_RS02400	COG4607	ABC-type enterochelin transport system periplasmic component
OU809_RS02405	COG2814	Major facilitator Superfamily
OU809_RS02410	COG1309	transcriptional regulator
OU809_RS02420	COG0778	Nitroreductase
OU809_RS02425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OU809_RS02430	COG0640	Transcriptional regulator
OU809_RS02435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS02440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OU809_RS02445	COG0531	amino acid
OU809_RS02450	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS02455	COG0697	spore germination
OU809_RS02465	COG4549	nuclear export factor GLE1
OU809_RS02470	COG1276	copper resistance
OU809_RS02470	COG2372	response to copper ion
OU809_RS02475	COG1349	DNA-binding transcription factor activity
OU809_RS02480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OU809_RS02485	COG0243	molybdopterin cofactor binding
OU809_RS02490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OU809_RS02495	COG2146	nitrite reductase [NAD(P)H] activity
OU809_RS02500	COG1587	Uroporphyrinogen-III synthase
OU809_RS02500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OU809_RS02505	COG1802	Transcriptional regulator
OU809_RS02510	COG0471	metal ion transport
OU809_RS02515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OU809_RS02525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS02540	COG3959	Transketolase, thiamine diphosphate binding domain
OU809_RS02545	COG3958	Transketolase
OU809_RS02550	COG0561	phosphatase activity
OU809_RS02555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OU809_RS02560	COG1914	H( )-stimulated, divalent metal cation uptake system
OU809_RS02565	COG4336	lyase activity
OU809_RS02570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OU809_RS02575	COG1984	allophanate hydrolase subunit 2
OU809_RS02580	COG1414	Transcriptional regulator
OU809_RS02585	COG2755	lipolytic protein G-D-S-L family
OU809_RS02590	COG2213	PTS system mannitol-specific
OU809_RS02595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS02600	COG0246	Mannitol dehydrogenase
OU809_RS02605	COG3711	transcriptional antiterminator
OU809_RS02610	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS02615	COG1917	Cupin 2, conserved barrel domain protein
OU809_RS02625	COG3871	stress protein (general stress protein 26)
OU809_RS02640	COG2814	Major facilitator Superfamily
OU809_RS02650	COG1522	sequence-specific DNA binding
OU809_RS02655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OU809_RS02655	COG0551	DNA topoisomerase type I activity
OU809_RS02660	COG0287	Prephenate dehydrogenase
OU809_RS02665	COG0512	Glutamine amidotransferase of anthranilate synthase
OU809_RS02665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OU809_RS02670	COG1605	Chorismate mutase
OU809_RS02675	COG0028	Belongs to the TPP enzyme family
OU809_RS02690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS02695	COG1914	H( )-stimulated, divalent metal cation uptake system
OU809_RS02700	COG2261	transglycosylase associated protein
OU809_RS02705	COG1027	Aspartate ammonia-lyase
OU809_RS02710	COG1819	glycosyl
OU809_RS02715	COG4876	unkown
OU809_RS02720	COG2217	Heavy metal translocating P-type atpase
OU809_RS02730	COG0662	Cupin 2, conserved barrel domain protein
OU809_RS02740	COG0628	permease
OU809_RS02745	COG1301	dicarboxylic acid transport
OU809_RS02750	COG1131	(ABC) transporter
OU809_RS02755	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU809_RS02765	COG1960	acyl-CoA dehydrogenase activity
OU809_RS02780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS02785	COG1181	Belongs to the D-alanine--D-alanine ligase family
OU809_RS02790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OU809_RS02800	COG0513	Belongs to the DEAD box helicase family
OU809_RS02805	COG3402	PFAM membrane-flanked domain
OU809_RS02810	COG3428	Bacterial PH domain
OU809_RS02815	COG0705	Rhomboid family
OU809_RS02820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OU809_RS02825	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OU809_RS02830	COG0864	Transcriptional regulator
OU809_RS02835	COG2337	Toxic component of a toxin-antitoxin (TA) module
OU809_RS02840	COG1366	Belongs to the anti-sigma-factor antagonist family
OU809_RS02845	COG1366	Belongs to the anti-sigma-factor antagonist family
OU809_RS02850	COG2172	sigma factor antagonist activity
OU809_RS02855	COG2208	phosphoserine phosphatase activity
OU809_RS02870	COG1191	sigma factor activity
OU809_RS02875	COG2208	phosphoserine phosphatase activity
OU809_RS02880	COG2183	response to ionizing radiation
OU809_RS02885	COG1309	transcriptional regulator
OU809_RS02895	COG1033	growth of symbiont in host cell
OU809_RS02895	COG2409	Drug exporters of the RND superfamily
OU809_RS02905	COG3091	SprT-like family
OU809_RS02945	COG0582	viral genome integration into host DNA
OU809_RS02970	COG0726	polysaccharide deacetylase
OU809_RS02985	COG1278	Cold shock
OU809_RS02995	COG1329	Transcriptional regulator
OU809_RS03005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS03010	COG0477	Major facilitator Superfamily
OU809_RS03020	COG2364	Membrane
OU809_RS03025	COG1846	Transcriptional regulator
OU809_RS03030	COG0456	acetyltransferase
OU809_RS03035	COG2808	Putative FMN-binding domain
OU809_RS03045	COG1733	regulation of RNA biosynthetic process
OU809_RS03050	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS03065	COG3545	Serine hydrolase
OU809_RS03070	COG1733	regulation of RNA biosynthetic process
OU809_RS03080	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
OU809_RS03100	COG0596	Alpha beta hydrolase
OU809_RS03105	COG5566	PFAM Mor transcription activator
OU809_RS03110	COG1595	DNA-templated transcription, initiation
OU809_RS03120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OU809_RS03120	COG2755	lipolytic protein G-D-S-L family
OU809_RS03125	COG0494	nUDIX hydrolase
OU809_RS03130	COG2814	Major facilitator Superfamily
OU809_RS03135	COG1979	alcohol dehydrogenase
OU809_RS03140	COG0745	RESPONSE REGULATOR receiver
OU809_RS03140	COG2972	Histidine kinase
OU809_RS03150	COG3279	Response regulator of the LytR AlgR family
OU809_RS03160	COG3764	Sortase (surface protein transpeptidase)
OU809_RS03165	COG2814	Major facilitator Superfamily
OU809_RS03205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OU809_RS03210	COG0802	atpase or kinase
OU809_RS03215	COG1214	PFAM Peptidase M22, glycoprotease
OU809_RS03220	COG0456	acetyltransferase
OU809_RS03225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OU809_RS03230	COG0488	(ABC) transporter
OU809_RS03235	COG0315	cyclic pyranopterin monophosphate synthase activity
OU809_RS03240	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OU809_RS03245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OU809_RS03250	COG0805	protein transport
OU809_RS03260	COG1266	CAAX protease self-immunity
OU809_RS03265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OU809_RS03270	COG0459	protein refolding
OU809_RS03275	COG2720	vancomycin resistance protein
OU809_RS03295	COG2135	peptidase activity
OU809_RS03305	COG1309	transcriptional regulator
OU809_RS03310	COG0574	Belongs to the PEP-utilizing enzyme family
OU809_RS03310	COG3848	Pyruvate phosphate dikinase
OU809_RS03325	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OU809_RS03330	COG2272	Belongs to the type-B carboxylesterase lipase family
OU809_RS03335	COG2814	Major facilitator Superfamily
OU809_RS03340	COG1842	Phage shock protein A
OU809_RS03345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OU809_RS03350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OU809_RS03355	COG4260	virion core protein, lumpy skin disease virus
OU809_RS03365	COG1378	Sugar-specific transcriptional regulator TrmB
OU809_RS03370	COG1280	lysine exporter protein (LysE YggA)
OU809_RS03375	COG3339	Conserved Protein
OU809_RS03380	COG0772	Belongs to the SEDS family
OU809_RS03385	COG0772	Belongs to the SEDS family
OU809_RS03405	COG0726	polysaccharide deacetylase
OU809_RS03415	COG1609	Transcriptional regulator
OU809_RS03420	COG0366	Alpha amylase catalytic
OU809_RS03425	COG2182	Extracellular solute-binding protein
OU809_RS03430	COG1175	transmembrane transport
OU809_RS03435	COG3833	ABC-type maltose transport systems, permease component
OU809_RS03440	COG5521	maltodextrose utilization protein MalA
OU809_RS03445	COG1554	hydrolase, family 65, central catalytic
OU809_RS03450	COG0366	Alpha amylase catalytic
OU809_RS03455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OU809_RS03460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OU809_RS03465	COG1846	Transcriptional regulator
OU809_RS03480	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OU809_RS03485	COG0823	Involved in the tonB-independent uptake of proteins
OU809_RS03510	COG0702	epimerase
OU809_RS03520	COG2132	Multicopper oxidase
OU809_RS03540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OU809_RS03545	COG0714	Associated with various cellular activities
OU809_RS03550	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OU809_RS03555	COG1305	Transglutaminase-like
OU809_RS03560	COG0519	Catalyzes the synthesis of GMP from XMP
OU809_RS03560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OU809_RS03570	COG2252	PERMEase
OU809_RS03585	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
OU809_RS03595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OU809_RS03600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OU809_RS03605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OU809_RS03610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OU809_RS03615	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OU809_RS03620	COG0047	phosphoribosylformylglycinamidine synthase activity
OU809_RS03625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OU809_RS03630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OU809_RS03635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OU809_RS03640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OU809_RS03645	COG0138	bifunctional purine biosynthesis protein purh
OU809_RS03650	COG0151	Belongs to the GarS family
OU809_RS03660	COG2124	cytochrome p450
OU809_RS03685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OU809_RS03690	COG1470	cell adhesion involved in biofilm formation
OU809_RS03695	COG4496	protein, YerC YecD
OU809_RS03700	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OU809_RS03705	COG0210	DNA helicase
OU809_RS03710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OU809_RS03715	COG4851	CamS sex pheromone cAM373 precursor
OU809_RS03720	COG2188	Transcriptional regulator
OU809_RS03740	COG1735	metal-dependent hydrolase with the TIM-barrel fold
OU809_RS03745	COG0626	cystathionine gamma-synthase activity
OU809_RS03750	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OU809_RS03755	COG3457	Alanine racemase
OU809_RS03760	COG0363	glucosamine-6-phosphate deaminase activity
OU809_RS03765	COG1285	pathogenesis
OU809_RS03770	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS03775	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OU809_RS03780	COG0154	amidase activity
OU809_RS03785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OU809_RS03800	COG4124	Belongs to the glycosyl hydrolase 26 family
OU809_RS03805	COG1309	transcriptional regulator
OU809_RS03810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OU809_RS03820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS03825	COG1957	nucleoside hydrolase
OU809_RS03830	COG1597	lipid kinase activity
OU809_RS03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OU809_RS03865	COG2723	6-phospho-beta-galactosidase activity
OU809_RS03870	COG3711	transcriptional antiterminator
OU809_RS03875	COG0457	Tetratricopeptide repeat
OU809_RS03890	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
OU809_RS03890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU809_RS03895	COG3586	endonuclease activity
OU809_RS03900	COG0697	spore germination
OU809_RS03905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS03915	COG0217	transcriptional regulatory protein
OU809_RS03945	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS03950	COG0840	transmembrane signaling receptor activity
OU809_RS03955	COG0109	protoheme IX farnesyltransferase activity
OU809_RS03960	COG1309	transcriptional regulator
OU809_RS03965	COG0471	metal ion transport
OU809_RS03970	COG0488	(ABC) transporter
OU809_RS03975	COG0583	DNA-binding transcription factor activity
OU809_RS03990	COG1469	GTP cyclohydrolase I activity
OU809_RS04005	COG0523	cobalamin synthesis protein
OU809_RS04010	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OU809_RS04015	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OU809_RS04020	COG0156	8-amino-7-oxononanoate synthase activity
OU809_RS04025	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OU809_RS04030	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OU809_RS04035	COG2124	cytochrome p450
OU809_RS04045	COG0789	Transcriptional regulator
OU809_RS04050	COG2814	Major facilitator Superfamily
OU809_RS04055	COG0488	(ABC) transporter
OU809_RS04060	COG0513	Belongs to the DEAD box helicase family
OU809_RS04065	COG2130	NADP-dependent
OU809_RS04080	COG0471	metal ion transport
OU809_RS04095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS04105	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OU809_RS04110	COG3858	chitin binding
OU809_RS04115	COG5658	integral membrane protein
OU809_RS04120	COG0640	Transcriptional regulator
OU809_RS04125	COG1254	Belongs to the acylphosphatase family
OU809_RS04130	COG2258	MOSC domain
OU809_RS04145	COG0024	Methionine aminopeptidase
OU809_RS04150	COG1368	sulfuric ester hydrolase activity
OU809_RS04160	COG1115	amino acid carrier protein
OU809_RS04165	COG1263	PTS System
OU809_RS04165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS04170	COG0366	Alpha amylase catalytic
OU809_RS04175	COG2188	Transcriptional regulator
OU809_RS04200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU809_RS04205	COG1045	serine acetyltransferase
OU809_RS04210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU809_RS04220	COG1215	transferase activity, transferring glycosyl groups
OU809_RS04225	COG0463	Glycosyl transferase, family 2
OU809_RS04225	COG0457	Tetratricopeptide repeat
OU809_RS04235	COG0673	inositol 2-dehydrogenase activity
OU809_RS04250	COG1733	regulation of RNA biosynthetic process
OU809_RS04255	COG0778	Nitroreductase
OU809_RS04260	COG0737	Belongs to the 5'-nucleotidase family
OU809_RS04265	COG0693	protein deglycase activity
OU809_RS04270	COG4840	Belongs to the UPF0435 family
OU809_RS04275	COG1115	amino acid carrier protein
OU809_RS04280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OU809_RS04285	COG4980	gas vesicle protein
OU809_RS04290	COG1295	ribonuclease BN
OU809_RS04295	COG0477	Major facilitator Superfamily
OU809_RS04305	COG0387	Pfam Sodium calcium exchanger
OU809_RS04315	COG0535	radical SAM domain protein
OU809_RS04325	COG0726	polysaccharide deacetylase
OU809_RS04330	COG0371	Dehydrogenase
OU809_RS04340	COG0598	Magnesium transport protein CorA
OU809_RS04345	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OU809_RS04350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OU809_RS04355	COG4637	Psort location Cytoplasmic, score
OU809_RS04380	COG1819	glycosyl
OU809_RS04390	COG0477	Major facilitator Superfamily
OU809_RS04400	COG1263	PTS System
OU809_RS04400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS04405	COG3711	transcriptional antiterminator
OU809_RS04410	COG0288	reversible hydration of carbon dioxide
OU809_RS04415	COG3002	Belongs to the UPF0753 family
OU809_RS04420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OU809_RS04425	COG5609	conserved protein (DUF2294)
OU809_RS04435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU809_RS04440	COG0022	dehydrogenase e1 component
OU809_RS04445	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU809_RS04450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU809_RS04455	COG3284	Transcriptional regulator
OU809_RS04460	COG1742	UPF0060 membrane protein
OU809_RS04465	COG1486	melibiose metabolic process
OU809_RS04470	COG1737	Transcriptional regulator
OU809_RS04475	COG1263	PTS System
OU809_RS04475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS04490	COG1733	regulation of RNA biosynthetic process
OU809_RS04495	COG2259	Doxx family
OU809_RS04500	COG2514	catechol 2,3-dioxygenase activity
OU809_RS04510	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS04515	COG2207	Transcriptional regulator
OU809_RS04515	COG1917	Cupin 2, conserved barrel domain protein
OU809_RS04520	COG1653	transport
OU809_RS04525	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU809_RS04530	COG1051	belongs to the nudix hydrolase family
OU809_RS04540	COG0392	lysyltransferase activity
OU809_RS04540	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OU809_RS04545	COG0384	phenazine biosynthesis protein PhzF
OU809_RS04550	COG0778	Nitroreductase
OU809_RS04570	COG1090	epimerase
OU809_RS04575	COG2137	regulation of response to DNA damage stimulus
OU809_RS04600	COG0463	Glycosyl transferase, family 2
OU809_RS04610	COG4485	Bacterial membrane protein, YfhO
OU809_RS04615	COG1988	membrane-bound metal-dependent
OU809_RS04620	COG1194	a g-specific adenine glycosylase
OU809_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS04645	COG3557	Belongs to the UPF0374 family
OU809_RS04650	COG1132	(ABC) transporter
OU809_RS04655	COG0444	Belongs to the ABC transporter superfamily
OU809_RS04660	COG4608	Belongs to the ABC transporter superfamily
OU809_RS04665	COG0747	negative chemotaxis
OU809_RS04670	COG0601	transmembrane transport
OU809_RS04675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS04680	COG4129	membrane
OU809_RS04685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OU809_RS04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OU809_RS04695	COG0735	belongs to the Fur family
OU809_RS04805	COG0457	Tetratricopeptide repeat
OU809_RS04825	COG5444	nuclease activity
OU809_RS04830	COG0457	Tetratricopeptide repeat
OU809_RS04835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OU809_RS04855	COG0710	3-dehydroquinate dehydratase activity
OU809_RS04860	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OU809_RS04865	COG1116	anion transmembrane transporter activity
OU809_RS04870	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OU809_RS04875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OU809_RS04880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU809_RS04890	COG1476	TRANSCRIPTIONal
OU809_RS04900	COG1131	(ABC) transporter
OU809_RS04920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OU809_RS04930	COG3382	B3 4 domain protein
OU809_RS04935	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OU809_RS04945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OU809_RS04950	COG0789	Transcriptional regulator
OU809_RS04955	COG1664	Polymer-forming cytoskeletal
OU809_RS04960	COG1664	Polymer-forming cytoskeletal
OU809_RS04970	COG2766	serine protein kinase
OU809_RS04975	COG2718	Belongs to the UPF0229 family
OU809_RS04980	COG1566	PFAM secretion protein HlyD family protein
OU809_RS04985	COG2814	Major facilitator Superfamily
OU809_RS04990	COG0655	NAD(P)H dehydrogenase (quinone) activity
OU809_RS05005	COG1725	Transcriptional regulator
OU809_RS05010	COG1131	(ABC) transporter
OU809_RS05015	COG1131	(ABC) transporter
OU809_RS05020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU809_RS05025	COG1278	Cold shock
OU809_RS05030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OU809_RS05035	COG2011	ABC-type metal ion transport system permease component
OU809_RS05040	COG1464	Belongs to the NlpA lipoprotein family
OU809_RS05045	COG1823	symporter activity
OU809_RS05070	COG5577	PFAM Coat F domain
OU809_RS05075	COG5002	protein histidine kinase activity
OU809_RS05080	COG1525	nuclease
OU809_RS05080	COG4085	toxin activity
OU809_RS05080	COG0737	Belongs to the 5'-nucleotidase family
OU809_RS05085	COG3764	Sortase (surface protein transpeptidase)
OU809_RS05090	COG0564	pseudouridine synthase activity
OU809_RS05100	COG0517	IMP dehydrogenase activity
OU809_RS05105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OU809_RS05110	COG3153	acetyltransferase
OU809_RS05110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OU809_RS05115	COG0488	(ABC) transporter
OU809_RS05120	COG2116	formate transmembrane transporter activity
OU809_RS05135	COG0604	alcohol dehydrogenase
OU809_RS05140	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OU809_RS05145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OU809_RS05150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OU809_RS05155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OU809_RS05160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OU809_RS05175	COG2203	Gaf domain
OU809_RS05175	COG4585	Histidine kinase
OU809_RS05180	COG2197	response regulator
OU809_RS05185	COG0431	NADPH-dependent FMN reductase
OU809_RS05200	COG1959	2 iron, 2 sulfur cluster binding
OU809_RS05205	COG1017	nitric oxide dioxygenase activity
OU809_RS05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OU809_RS05210	COG2719	SpoVR family
OU809_RS05215	COG1388	LysM domain
OU809_RS05215	COG0791	NLP P60 protein
OU809_RS05220	COG0583	DNA-binding transcription factor activity
OU809_RS05225	COG0372	Belongs to the citrate synthase family
OU809_RS05230	COG2133	pyrroloquinoline quinone binding
OU809_RS05235	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS05240	COG0733	neurotransmitter:sodium symporter activity
OU809_RS05265	COG5444	nuclease activity
OU809_RS05270	COG2207	Transcriptional regulator
OU809_RS05270	COG3708	Transcriptional regulator
OU809_RS05275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS05295	COG1595	DNA-templated transcription, initiation
OU809_RS05300	COG0662	Cupin 2, conserved barrel domain protein
OU809_RS05305	COG0667	Aldo Keto reductase
OU809_RS05310	COG0204	Acyl-transferase
OU809_RS05315	COG3152	Membrane
OU809_RS05330	COG1253	flavin adenine dinucleotide binding
OU809_RS05335	COG0789	Transcriptional regulator
OU809_RS05340	COG1253	flavin adenine dinucleotide binding
OU809_RS05360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OU809_RS05365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OU809_RS05370	COG0584	glycerophosphoryl diester phosphodiesterase
OU809_RS05380	COG0668	transmembrane transport
OU809_RS05385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OU809_RS05395	COG0726	polysaccharide deacetylase
OU809_RS05405	COG1757	Na H antiporter
OU809_RS05410	COG2017	converts alpha-aldose to the beta-anomer
OU809_RS05440	COG0589	response to stress
OU809_RS05445	COG1132	(ABC) transporter
OU809_RS05450	COG1132	(ABC) transporter
OU809_RS05455	COG0702	epimerase
OU809_RS05475	COG3842	ATPase activity
OU809_RS05480	COG2508	Transcriptional regulator
OU809_RS05490	COG0189	ligase activity
OU809_RS05495	COG0189	ligase activity
OU809_RS05500	COG4399	Belongs to the UPF0754 family
OU809_RS05505	COG3679	Belongs to the UPF0342 family
OU809_RS05510	COG0561	phosphatase activity
OU809_RS05515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OU809_RS05520	COG0475	glutathione-regulated potassium exporter activity
OU809_RS05525	COG0490	domain, Protein
OU809_RS05535	COG1024	Enoyl-CoA hydratase
OU809_RS05540	COG0457	Tetratricopeptide repeat
OU809_RS05560	COG4152	abc transporter atp-binding protein
OU809_RS05565	COG1668	transmembrane transport
OU809_RS05570	COG0420	3'-5' exonuclease activity
OU809_RS05575	COG4717	serine-type aminopeptidase activity
OU809_RS05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
OU809_RS05590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OU809_RS05620	COG1846	Transcriptional regulator
OU809_RS05625	COG4980	gas vesicle protein
OU809_RS05640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OU809_RS05645	COG0537	adenosine 5'-monophosphoramidase activity
OU809_RS05650	COG1131	(ABC) transporter
OU809_RS05655	COG4473	ABC transporter
OU809_RS05665	COG1473	amidohydrolase
OU809_RS05670	COG3069	C4-dicarboxylate transmembrane transporter activity
OU809_RS05675	COG2329	Antibiotic biosynthesis monooxygenase
OU809_RS05680	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU809_RS05685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OU809_RS05690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OU809_RS05695	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OU809_RS05700	COG1309	transcriptional regulator
OU809_RS05705	COG1511	domain protein
OU809_RS05710	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU809_RS05715	COG1363	Peptidase, m42
OU809_RS05725	COG1301	dicarboxylic acid transport
OU809_RS05735	COG1234	tRNA 3'-trailer cleavage
OU809_RS05740	COG0095	Lipoate-protein ligase
OU809_RS05745	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS05755	COG1396	sequence-specific DNA binding
OU809_RS05770	COG0501	Belongs to the peptidase M48B family
OU809_RS05780	COG0697	spore germination
OU809_RS05785	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OU809_RS05790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS05795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS05800	COG0406	alpha-ribazole phosphatase activity
OU809_RS05805	COG0183	Belongs to the thiolase family
OU809_RS05810	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS05815	COG1268	BioY protein
OU809_RS05820	COG0840	transmembrane signaling receptor activity
OU809_RS05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OU809_RS05825	COG0723	plastoquinol--plastocyanin reductase activity
OU809_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS05840	COG4903	ComK protein
OU809_RS05850	COG0398	Pfam SNARE associated Golgi protein
OU809_RS05855	COG0681	Belongs to the peptidase S26 family
OU809_RS05860	COG1404	Belongs to the peptidase S8 family
OU809_RS05865	COG2003	Belongs to the UPF0758 family
OU809_RS05870	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OU809_RS05875	COG3421	Type III restriction
OU809_RS05890	COG2508	Transcriptional regulator
OU809_RS05895	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OU809_RS05900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU809_RS05905	COG3257	ureidoglycine aminohydrolase activity
OU809_RS05910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OU809_RS05915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OU809_RS05920	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OU809_RS05925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OU809_RS05935	COG0549	Belongs to the carbamate kinase family
OU809_RS05940	COG2814	Major facilitator Superfamily
OU809_RS05950	COG0457	Tetratricopeptide repeat
OU809_RS05960	COG1609	Transcriptional regulator
OU809_RS05965	COG1653	transport
OU809_RS05970	COG1175	transmembrane transport
OU809_RS05975	COG0395	ABC-type sugar transport system, permease component
OU809_RS05980	COG1486	melibiose metabolic process
OU809_RS05985	COG3180	Ammonia monooxygenase
OU809_RS06000	COG3546	catalase activity
OU809_RS06005	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS06010	COG0477	Major facilitator Superfamily
OU809_RS06010	COG2814	Major facilitator Superfamily
OU809_RS06015	COG4533	DNA binding
OU809_RS06025	COG5002	protein histidine kinase activity
OU809_RS06030	COG0745	RESPONSE REGULATOR receiver
OU809_RS06035	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OU809_RS06040	COG0725	ABC transporter, periplasmic molybdate-binding protein
OU809_RS06045	COG4149	molybdate abc transporter
OU809_RS06050	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
OU809_RS06055	COG1074	ATP-dependent DNA helicase activity
OU809_RS06060	COG0420	3'-5' exonuclease activity
OU809_RS06065	COG0419	ATPase involved in DNA repair
OU809_RS06110	COG5337	Spore coat protein CotH
OU809_RS06120	COG0179	Fumarylacetoacetate (FAA) hydrolase
OU809_RS06140	COG0367	asparagine synthase
OU809_RS06145	COG0004	ammonium transporteR
OU809_RS06150	COG0347	Belongs to the P(II) protein family
OU809_RS06155	COG0534	Mate efflux family protein
OU809_RS06160	COG1917	Cupin 2, conserved barrel domain protein
OU809_RS06160	COG2207	Transcriptional regulator
OU809_RS06170	COG1609	Transcriptional regulator
OU809_RS06175	COG0673	inositol 2-dehydrogenase activity
OU809_RS06190	COG0697	spore germination
OU809_RS06200	COG1279	arginine transmembrane transporter activity
OU809_RS06205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS06215	COG0076	glutamate decarboxylase activity
OU809_RS06240	COG2153	protein acetylation
OU809_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS06250	COG2378	regulation of single-species biofilm formation
OU809_RS06255	COG1410	methionine synthase
OU809_RS06255	COG0646	methionine synthase
OU809_RS06260	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OU809_RS06260	COG0646	methionine synthase
OU809_RS06265	COG1666	GTP binding
OU809_RS06270	COG2996	Protein conserved in bacteria
OU809_RS06285	COG1307	EDD domain protein, DegV family
OU809_RS06290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS06300	COG0516	GMP reductase activity
OU809_RS06315	COG0561	phosphatase activity
OU809_RS06320	COG1073	alpha beta
OU809_RS06325	COG2151	metal-sulfur cluster biosynthetic enzyme
OU809_RS06330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OU809_RS06335	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OU809_RS06340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OU809_RS06345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OU809_RS06350	COG0505	Belongs to the CarA family
OU809_RS06355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OU809_RS06360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OU809_RS06365	COG1968	undecaprenyl-diphosphatase activity
OU809_RS06380	COG2267	carboxylic ester hydrolase activity
OU809_RS06390	COG1744	ABC transporter substrate-binding protein PnrA-like
OU809_RS06405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU809_RS06410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OU809_RS06420	COG5504	Zn-dependent protease
OU809_RS06425	COG0444	Belongs to the ABC transporter superfamily
OU809_RS06430	COG4608	Belongs to the ABC transporter superfamily
OU809_RS06440	COG0601	transmembrane transport
OU809_RS06445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS06460	COG0180	Tryptophanyl-tRNA synthetase
OU809_RS06465	COG4166	transmembrane transport
OU809_RS06470	COG0601	transmembrane transport
OU809_RS06475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS06480	COG0444	Belongs to the ABC transporter superfamily
OU809_RS06485	COG4608	Belongs to the ABC transporter superfamily
OU809_RS06490	COG0456	acetyltransferase
OU809_RS06495	COG1393	Belongs to the ArsC family
OU809_RS06500	COG0861	Integral membrane protein TerC family
OU809_RS06510	COG4862	establishment of competence for transformation
OU809_RS06535	COG4565	transcriptional regulatory protein
OU809_RS06540	COG3290	protein histidine kinase activity
OU809_RS06545	COG4469	Competence protein
OU809_RS06550	COG1164	Oligoendopeptidase f
OU809_RS06560	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OU809_RS06565	COG2346	COG2346, Truncated hemoglobins
OU809_RS06570	COG0741	lytic transglycosylase activity
OU809_RS06575	COG4116	CYTH
OU809_RS06585	COG2357	RelA SpoT domain protein
OU809_RS06590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OU809_RS06595	COG0564	pseudouridine synthase activity
OU809_RS06600	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OU809_RS06605	COG0475	glutathione-regulated potassium exporter activity
OU809_RS06605	COG0569	domain protein
OU809_RS06610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OU809_RS06615	COG0352	thiamine-phosphate diphosphorylase activity
OU809_RS06625	COG2104	thiamine diphosphate biosynthetic process
OU809_RS06630	COG2022	thiamine diphosphate biosynthetic process
OU809_RS06635	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OU809_RS06640	COG0351	phosphomethylpyrimidine kinase
OU809_RS06645	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OU809_RS06705	COG0210	DNA helicase
OU809_RS06715	COG0586	Pfam SNARE associated Golgi protein
OU809_RS06720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU809_RS06725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OU809_RS06730	COG2246	polysaccharide biosynthetic process
OU809_RS06735	COG2153	protein acetylation
OU809_RS06740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OU809_RS06745	COG2382	esterase
OU809_RS06765	COG0626	cystathionine gamma-synthase activity
OU809_RS06770	COG0626	cystathionine gamma-synthase activity
OU809_RS06775	COG5505	Protein of unknown function (DUF819)
OU809_RS06790	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU809_RS06800	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS06820	COG0110	maltose O-acetyltransferase activity
OU809_RS06830	COG0583	DNA-binding transcription factor activity
OU809_RS06835	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OU809_RS06840	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OU809_RS06845	COG0583	DNA-binding transcription factor activity
OU809_RS06850	COG0697	spore germination
OU809_RS06855	COG0346	lactoylglutathione lyase activity
OU809_RS06865	COG3584	3D domain protein
OU809_RS06865	COG1388	LysM domain
OU809_RS06870	COG2814	Major facilitator Superfamily
OU809_RS06875	COG1309	transcriptional regulator
OU809_RS06895	COG5444	nuclease activity
OU809_RS06900	COG4195	phage-related replication protein
OU809_RS06905	COG2856	Zn peptidase
OU809_RS06910	COG1396	sequence-specific DNA binding
OU809_RS06925	COG1522	sequence-specific DNA binding
OU809_RS06930	COG1484	DNA-dependent DNA replication
OU809_RS06950	COG1595	DNA-templated transcription, initiation
OU809_RS06955	COG3728	DNA packaging
OU809_RS06955	COG5484	DNA packaging
OU809_RS06960	COG1783	phage Terminase large subunit
OU809_RS06965	COG5518	Phage portal protein
OU809_RS06970	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OU809_RS06975	COG4653	Phage capsid family
OU809_RS07025	COG5280	Phage tail tape measure protein TP901
OU809_RS07025	COG3953	SLT domain
OU809_RS07030	COG1652	LysM domain
OU809_RS07035	COG4193	domain, Protein
OU809_RS07045	COG3628	GPW Gp25 family protein
OU809_RS07050	COG3299	homolog of phage Mu protein gp47
OU809_RS07055	COG3778	Protein conserved in bacteria
OU809_RS07080	COG3594	Acyltransferase
OU809_RS07090	COG1802	Transcriptional regulator
OU809_RS07095	COG1063	alcohol dehydrogenase
OU809_RS07100	COG1312	Catalyzes the dehydration of D-mannonate
OU809_RS07105	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS07115	COG2271	Major facilitator Superfamily
OU809_RS07135	COG0306	phosphate transporter
OU809_RS07140	COG1392	Phosphate transport regulator
OU809_RS07145	COG0405	Gamma-glutamyltransferase
OU809_RS07150	COG5578	integral membrane protein
OU809_RS07155	COG2972	Histidine kinase
OU809_RS07160	COG2207	Transcriptional regulator
OU809_RS07160	COG4753	response regulator
OU809_RS07165	COG1653	transport
OU809_RS07170	COG1175	transmembrane transport
OU809_RS07175	COG0395	ABC-type sugar transport system, permease component
OU809_RS07180	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OU809_RS07185	COG2207	Transcriptional regulator
OU809_RS07190	COG2755	lipolytic protein G-D-S-L family
OU809_RS07200	COG5578	integral membrane protein
OU809_RS07205	COG3401	FG-GAP repeat protein
OU809_RS07210	COG2755	lipolytic protein G-D-S-L family
OU809_RS07215	COG3401	FG-GAP repeat protein
OU809_RS07220	COG0667	Aldo Keto reductase
OU809_RS07225	COG2755	lipolytic protein G-D-S-L family
OU809_RS07230	COG1874	Beta-galactosidase
OU809_RS07240	COG1653	transport
OU809_RS07245	COG4209	transmembrane transport
OU809_RS07250	COG0395	ABC-type sugar transport system, permease component
OU809_RS07255	COG0531	amino acid
OU809_RS07260	COG0346	lactoylglutathione lyase activity
OU809_RS07265	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU809_RS07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OU809_RS07275	COG2362	D-Aminopeptidase
OU809_RS07280	COG0601	transmembrane transport
OU809_RS07285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS07290	COG0444	Belongs to the ABC transporter superfamily
OU809_RS07295	COG4166	transmembrane transport
OU809_RS07300	COG1619	proteins homologs of microcin C7 resistance protein MccF
OU809_RS07305	COG4948	Mandelate Racemase Muconate Lactonizing
OU809_RS07310	COG0791	NLP P60 protein
OU809_RS07315	COG4608	Belongs to the ABC transporter superfamily
OU809_RS07320	COG1834	amidinotransferase
OU809_RS07325	COG1607	acyl-coa hydrolase
OU809_RS07330	COG2323	membrane
OU809_RS07335	COG3866	Pectate lyase
OU809_RS07355	COG2318	DinB family
OU809_RS07360	COG2076	Multidrug Resistance protein
OU809_RS07365	COG2076	Multidrug Resistance protein
OU809_RS07370	COG0788	formyltetrahydrofolate deformylase activity
OU809_RS07375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OU809_RS07380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OU809_RS07385	COG1764	response to oxidative stress
OU809_RS07395	COG1846	Transcriptional regulator
OU809_RS07400	COG1764	response to oxidative stress
OU809_RS07410	COG0590	tRNA wobble adenosine to inosine editing
OU809_RS07415	COG0406	alpha-ribazole phosphatase activity
OU809_RS07430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OU809_RS07435	COG1404	Belongs to the peptidase S8 family
OU809_RS07445	COG2239	Acts as a magnesium transporter
OU809_RS07455	COG0789	Transcriptional regulator
OU809_RS07470	COG1846	Transcriptional regulator
OU809_RS07475	COG3285	dna ligase
OU809_RS07475	COG1793	dna ligase
OU809_RS07480	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OU809_RS07485	COG5001	Diguanylate cyclase
OU809_RS07485	COG3300	MHYT domain
OU809_RS07490	COG0586	Pfam SNARE associated Golgi protein
OU809_RS07500	COG1191	sigma factor activity
OU809_RS07520	COG0501	Belongs to the peptidase M48B family
OU809_RS07525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OU809_RS07530	COG0768	penicillin binding
OU809_RS07550	COG3594	Acyltransferase
OU809_RS07555	COG5002	protein histidine kinase activity
OU809_RS07560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OU809_RS07570	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OU809_RS07575	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OU809_RS07580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OU809_RS07585	COG0436	Aminotransferase
OU809_RS07590	COG1850	ribulose-bisphosphate carboxylase activity
OU809_RS07595	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OU809_RS07595	COG0235	Class ii aldolase
OU809_RS07600	COG0235	Class ii aldolase
OU809_RS07600	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OU809_RS07605	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OU809_RS07610	COG0346	lactoylglutathione lyase activity
OU809_RS07615	COG3339	Conserved Protein
OU809_RS07625	COG3852	Histidine kinase
OU809_RS07630	COG1846	Transcriptional regulator
OU809_RS07635	COG1360	Flagellar Motor Protein
OU809_RS07640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OU809_RS07645	COG0542	response to heat
OU809_RS07650	COG3949	Membrane
OU809_RS07655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OU809_RS07660	COG0720	synthase
OU809_RS07665	COG0602	queuosine metabolic process
OU809_RS07670	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OU809_RS07680	COG0457	Tetratricopeptide repeat
OU809_RS07690	COG3739	integral membrane protein
OU809_RS07695	COG3655	Transcriptional regulator
OU809_RS07730	COG4873	Protein conserved in bacteria
OU809_RS07740	COG3773	Cell wall hydrolase
OU809_RS07745	COG2244	polysaccharide biosynthetic process
OU809_RS07750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS07755	COG2217	Heavy metal translocating P-type atpase
OU809_RS07760	COG0006	proline dipeptidase activity
OU809_RS07775	COG1609	Transcriptional regulator
OU809_RS07780	COG3711	transcriptional antiterminator
OU809_RS07785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS07785	COG1263	PTS System
OU809_RS07785	COG2190	(PTS) system
OU809_RS07790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS07795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OU809_RS07805	COG1533	DNA photolyase activity
OU809_RS07810	COG0456	acetyltransferase
OU809_RS07815	COG0840	transmembrane signaling receptor activity
OU809_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS07825	COG2084	Dehydrogenase
OU809_RS07830	COG2340	Cysteine-rich secretory protein family
OU809_RS07835	COG0768	penicillin binding
OU809_RS07840	COG4191	Histidine kinase
OU809_RS07845	COG0436	Aminotransferase
OU809_RS07855	COG1714	RDD family
OU809_RS07865	COG0784	Response regulator, receiver
OU809_RS07865	COG0835	chemotaxis
OU809_RS07875	COG2814	Major facilitator Superfamily
OU809_RS07880	COG1376	ErfK ybiS ycfS ynhG family protein
OU809_RS07885	COG1408	metallophosphoesterase
OU809_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS07895	COG2200	EAL domain
OU809_RS07905	COG4703	Protein of unknown function (DUF1797)
OU809_RS07915	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OU809_RS07925	COG0517	IMP dehydrogenase activity
OU809_RS07930	COG0583	DNA-binding transcription factor activity
OU809_RS07935	COG0716	FMN binding
OU809_RS07945	COG0716	FMN binding
OU809_RS07950	COG2171	N-acyltransferase activity
OU809_RS07955	COG1473	amidohydrolase
OU809_RS07965	COG0450	alkyl hydroperoxide reductase
OU809_RS07970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS07985	COG0746	molybdenum cofactor guanylyltransferase activity
OU809_RS07990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OU809_RS07995	COG0303	'Molybdopterin
OU809_RS08000	COG1763	Mo-molybdopterin cofactor biosynthetic process
OU809_RS08005	COG0314	molybdopterin synthase activity
OU809_RS08010	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OU809_RS08020	COG1132	(ABC) transporter
OU809_RS08025	COG1132	(ABC) transporter
OU809_RS08035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OU809_RS08040	COG1136	(ABC) transporter
OU809_RS08045	COG0577	efflux transmembrane transporter activity
OU809_RS08050	COG1349	DNA-binding transcription factor activity
OU809_RS08055	COG1105	Belongs to the carbohydrate kinase PfkB family
OU809_RS08060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS08060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS08060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS08080	COG0488	(ABC) transporter
OU809_RS08090	COG2309	aminopeptidase activity
OU809_RS08100	COG1077	Cell shape determining protein MreB Mrl
OU809_RS08105	COG2002	toxin-antitoxin pair type II binding
OU809_RS08110	COG3852	Histidine kinase
OU809_RS08115	COG0569	domain protein
OU809_RS08120	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OU809_RS08125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OU809_RS08130	COG5503	Protein of unknown function (DUF1447)
OU809_RS08135	COG0561	phosphatase activity
OU809_RS08140	COG0242	peptide deformylase activity
OU809_RS08150	COG0497	DNA recombination
OU809_RS08155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU809_RS08160	COG0022	dehydrogenase e1 component
OU809_RS08165	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU809_RS08170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU809_RS08175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS08185	COG1982	Orn Lys Arg decarboxylase major
OU809_RS08190	COG4476	Belongs to the UPF0223 family
OU809_RS08195	COG4493	Belongs to the UPF0637 family
OU809_RS08205	COG0483	inositol monophosphate 1-phosphatase activity
OU809_RS08220	COG1217	gtp-binding protein TYPA
OU809_RS08230	COG1846	Transcriptional regulator
OU809_RS08235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OU809_RS08240	COG4896	Protein conserved in bacteria
OU809_RS08250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OU809_RS08255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OU809_RS08260	COG2066	Belongs to the glutaminase family
OU809_RS08265	COG4838	Belongs to the UPF0358 family
OU809_RS08270	COG0772	Belongs to the SEDS family
OU809_RS08275	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OU809_RS08280	COG1612	heme a metabolic process
OU809_RS08285	COG0109	protoheme IX farnesyltransferase activity
OU809_RS08290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OU809_RS08290	COG2010	Cytochrome c
OU809_RS08295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OU809_RS08300	COG1845	cytochrome c oxidase, subunit III
OU809_RS08305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OU809_RS08310	COG3336	cytochrome c oxidase
OU809_RS08320	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OU809_RS08325	COG2340	Cysteine-rich secretory protein family
OU809_RS08345	COG3679	Belongs to the UPF0342 family
OU809_RS08350	COG4471	UPF0298 protein
OU809_RS08360	COG0742	ribosomal rna small subunit methyltransferase
OU809_RS08365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OU809_RS08370	COG3314	Sporulation integral membrane protein YlbJ
OU809_RS08375	COG3480	Lon protease (S16) C-terminal proteolytic domain
OU809_RS08380	COG1323	Belongs to the UPF0348 family
OU809_RS08385	COG1399	metal-binding, possibly nucleic acid-binding protein
OU809_RS08390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OU809_RS08400	COG0454	-acetyltransferase
OU809_RS08405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OU809_RS08410	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OU809_RS08415	COG2001	Belongs to the MraZ family
OU809_RS08420	COG0275	rRNA processing
OU809_RS08425	COG4839	cell division protein FtsL
OU809_RS08430	COG0768	penicillin binding
OU809_RS08435	COG0768	penicillin binding
OU809_RS08440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OU809_RS08445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OU809_RS08450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OU809_RS08455	COG0772	Belongs to the SEDS family
OU809_RS08460	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OU809_RS08465	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OU809_RS08470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OU809_RS08475	COG3879	Bacterial protein of unknown function (DUF881)
OU809_RS08480	COG3879	Bacterial protein of unknown function (DUF881)
OU809_RS08485	COG3856	small basic protein
OU809_RS08490	COG0849	cell division
OU809_RS08495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OU809_RS08505	COG1404	Belongs to the peptidase S8 family
OU809_RS08505	COG4412	M6 family metalloprotease domain protein
OU809_RS08515	COG1191	sigma factor activity
OU809_RS08520	COG1191	sigma factor activity
OU809_RS08525	COG1119	ATPase activity
OU809_RS08530	COG0500	methyltransferase
OU809_RS08535	COG1873	PFAM PRC-barrel domain
OU809_RS08540	COG1496	oxidoreductase activity
OU809_RS08545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OU809_RS08550	COG1799	cell septum assembly
OU809_RS08555	COG0762	integral membrane protein
OU809_RS08560	COG2302	S4 RNA-binding domain
OU809_RS08565	COG3599	regulation of cell shape
OU809_RS08570	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OU809_RS08575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU809_RS08580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OU809_RS08585	COG0564	pseudouridine synthase activity
OU809_RS08595	COG2233	PERMEase
OU809_RS08600	COG0540	Belongs to the ATCase OTCase family
OU809_RS08605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OU809_RS08610	COG0505	Belongs to the CarA family
OU809_RS08615	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OU809_RS08620	COG0543	2 iron, 2 sulfur cluster binding
OU809_RS08625	COG0167	dihydroorotate dehydrogenase activity
OU809_RS08630	COG0284	orotidine-5'-phosphate decarboxylase activity
OU809_RS08635	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OU809_RS08645	COG0175	sulfate reduction
OU809_RS08650	COG0306	phosphate transporter
OU809_RS08655	COG2046	Belongs to the sulfate adenylyltransferase family
OU809_RS08660	COG0529	Catalyzes the synthesis of activated sulfate
OU809_RS08665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OU809_RS08670	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OU809_RS08675	COG1648	precorrin-2 dehydrogenase activity
OU809_RS08685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OU809_RS08690	COG1561	YicC-like family, N-terminal region
OU809_RS08695	COG2052	Domain of unknown function (DUF370)
OU809_RS08700	COG0194	GDP metabolic process
OU809_RS08705	COG1758	RNA polymerase activity
OU809_RS08710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OU809_RS08715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OU809_RS08720	COG0242	peptide deformylase activity
OU809_RS08725	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OU809_RS08730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OU809_RS08730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OU809_RS08735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OU809_RS08740	COG0631	protein serine/threonine phosphatase activity
OU809_RS08745	COG2815	serine threonine protein kinase
OU809_RS08745	COG0515	serine threonine protein kinase
OU809_RS08750	COG1162	GTPase activity
OU809_RS08755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OU809_RS08760	COG1564	THIamine pyrophosphokinase
OU809_RS08770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OU809_RS08775	COG1302	Protein conserved in bacteria
OU809_RS08780	COG1461	Dihydroxyacetone kinase
OU809_RS08785	COG1760	l-serine dehydratase
OU809_RS08790	COG1760	l-serine dehydratase
OU809_RS08795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OU809_RS08800	COG1349	DNA-binding transcription factor activity
OU809_RS08805	COG0416	fatty acid biosynthetic process
OU809_RS08810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OU809_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS08820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU809_RS08825	COG0571	ribonuclease III activity
OU809_RS08830	COG1196	nuclear chromosome segregation
OU809_RS08835	COG0552	protein localization to endoplasmic reticulum
OU809_RS08840	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OU809_RS08845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OU809_RS08850	COG0228	four-way junction DNA binding
OU809_RS08855	COG1837	Belongs to the UPF0109 family
OU809_RS08865	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OU809_RS08870	COG0336	Belongs to the RNA methyltransferase TrmD family
OU809_RS08875	COG0335	large ribosomal subunit rRNA binding
OU809_RS08880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OU809_RS08885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OU809_RS08895	COG2257	FlhB HrpN YscU SpaS Family
OU809_RS08900	COG0045	succinate-CoA ligase (ADP-forming) activity
OU809_RS08905	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OU809_RS08910	COG0758	DNA mediated transformation
OU809_RS08915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OU809_RS08920	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OU809_RS08925	COG4974	Belongs to the 'phage' integrase family
OU809_RS08930	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OU809_RS08935	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OU809_RS08940	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OU809_RS08945	COG1815	bacterial-type flagellum-dependent cell motility
OU809_RS08950	COG1558	bacterial-type flagellum-dependent cell motility
OU809_RS08955	COG1677	Flagellar hook-basal body complex protein FliE
OU809_RS08960	COG1766	The M ring may be actively involved in energy transduction
OU809_RS08965	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU809_RS08970	COG1317	bacterial-type flagellum organization
OU809_RS08975	COG1157	protein secretion by the type III secretion system
OU809_RS08980	COG2882	bacterial-type flagellum organization
OU809_RS08985	COG3334	PFAM MgtE intracellular
OU809_RS08990	COG3144	bacterial-type flagellum assembly
OU809_RS08995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OU809_RS09000	COG4786	Flagellar basal body rod
OU809_RS09005	COG1582	Flagellar protein (FlbD)
OU809_RS09010	COG1580	Controls the rotational direction of flagella during chemotaxis
OU809_RS09015	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU809_RS09020	COG1776	CheC inhibitor of MCP methylation
OU809_RS09020	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OU809_RS09025	COG2201	protein-glutamate methylesterase activity
OU809_RS09030	COG3190	flagellar
OU809_RS09035	COG1338	Plays a role in the flagellum-specific transport system
OU809_RS09040	COG1987	bacterial-type flagellum assembly
OU809_RS09045	COG1684	flagellar biosynthetic protein fliR
OU809_RS09050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OU809_RS09055	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OU809_RS09060	COG1419	protein localization to endoplasmic reticulum
OU809_RS09065	COG0455	bacterial-type flagellum organization
OU809_RS09070	COG2201	protein-glutamate methylesterase activity
OU809_RS09075	COG0643	Histidine kinase
OU809_RS09075	COG2198	Histidine kinase
OU809_RS09080	COG0835	chemotaxis
OU809_RS09085	COG1776	CheC inhibitor of MCP methylation
OU809_RS09090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
OU809_RS09095	COG1191	sigma factor activity
OU809_RS09105	COG0052	Belongs to the universal ribosomal protein uS2 family
OU809_RS09110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OU809_RS09115	COG0528	UMP kinase activity
OU809_RS09120	COG0233	cytoplasmic translational termination
OU809_RS09125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OU809_RS09130	COG4589	Belongs to the CDS family
OU809_RS09135	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OU809_RS09140	COG0750	zinc metalloprotease
OU809_RS09145	COG0442	prolyl-tRNA aminoacylation
OU809_RS09150	COG2176	DNA-directed DNA polymerase activity
OU809_RS09175	COG0779	Required for maturation of 30S ribosomal subunits
OU809_RS09180	COG0195	Participates in both transcription termination and antitermination
OU809_RS09185	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OU809_RS09190	COG1358	cellular component organization or biogenesis
OU809_RS09195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OU809_RS09200	COG1550	Protein conserved in bacteria
OU809_RS09205	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OU809_RS09210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OU809_RS09215	COG0196	riboflavin kinase activity
OU809_RS09220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OU809_RS09225	COG1185	polyribonucleotide nucleotidyltransferase activity
OU809_RS09230	COG0726	polysaccharide deacetylase
OU809_RS09235	COG0612	Peptidase, M16
OU809_RS09240	COG1873	PFAM PRC-barrel domain
OU809_RS09245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU809_RS09250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OU809_RS09255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OU809_RS09260	COG0527	aspartate kinase activity
OU809_RS09270	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OU809_RS09275	COG0740	serine-type endopeptidase activity
OU809_RS09285	COG1674	ftsk spoiiie
OU809_RS09285	COG4980	gas vesicle protein
OU809_RS09290	COG2188	Transcriptional regulator
OU809_RS09295	COG2814	Major facilitator Superfamily
OU809_RS09300	COG0612	Peptidase, M16
OU809_RS09305	COG0612	Peptidase, M16
OU809_RS09310	COG0300	oxidoreductase activity
OU809_RS09325	COG1426	Protein conserved in bacteria
OU809_RS09330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OU809_RS09335	COG1546	Belongs to the CinA family
OU809_RS09335	COG1058	Belongs to the CinA family
OU809_RS09345	COG1418	mRNA catabolic process
OU809_RS09350	COG1692	metallophosphoesterase
OU809_RS09355	COG2359	stage V sporulation protein S
OU809_RS09365	COG1063	alcohol dehydrogenase
OU809_RS09375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OU809_RS09380	COG4550	Control of competence regulator ComK, YlbF/YmcA
OU809_RS09390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OU809_RS09395	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OU809_RS09400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OU809_RS09420	COG0457	Tetratricopeptide repeat
OU809_RS09425	COG5444	nuclease activity
OU809_RS09450	COG5484	DNA packaging
OU809_RS09460	COG5518	Phage portal protein
OU809_RS09465	COG2369	cell adhesion
OU809_RS09475	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OU809_RS09480	COG4653	Phage capsid family
OU809_RS09505	COG0523	cobalamin synthesis protein
OU809_RS09525	COG1231	oxidoreductase activity
OU809_RS09530	COG3619	membrane
OU809_RS09535	COG3263	regulation of cellular component size
OU809_RS09540	COG2814	Major facilitator Superfamily
OU809_RS09550	COG0393	Putative heavy-metal-binding
OU809_RS09555	COG0398	Pfam SNARE associated Golgi protein
OU809_RS09560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OU809_RS09565	COG1819	glycosyl
OU809_RS09570	COG0531	amino acid
OU809_RS09575	COG5577	PFAM Coat F domain
OU809_RS09585	COG1388	LysM domain
OU809_RS09585	COG3858	chitin binding
OU809_RS09590	COG1309	transcriptional regulator
OU809_RS09595	COG3631	Ketosteroid isomerase-related protein
OU809_RS09610	COG1764	response to oxidative stress
OU809_RS09615	COG2076	Multidrug Resistance protein
OU809_RS09635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OU809_RS09640	COG1923	regulation of RNA biosynthetic process
OU809_RS09650	COG1780	Probably involved in ribonucleotide reductase function
OU809_RS09655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OU809_RS09660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OU809_RS09665	COG4112	unkown
OU809_RS09680	COG0735	belongs to the Fur family
OU809_RS09685	COG1802	Transcriptional regulator
OU809_RS09690	COG0697	spore germination
OU809_RS09720	COG1309	transcriptional regulator
OU809_RS09760	COG4282	regulation of fungal-type cell wall biogenesis
OU809_RS09765	COG5444	nuclease activity
OU809_RS09790	COG2814	Major facilitator Superfamily
OU809_RS09795	COG0457	Tetratricopeptide repeat
OU809_RS09805	COG4413	Urea transporter
OU809_RS09810	COG0831	urea catabolic process
OU809_RS09815	COG0832	Belongs to the urease beta subunit family
OU809_RS09825	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OU809_RS09830	COG0830	nickel cation binding
OU809_RS09835	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OU809_RS09840	COG0829	nickel cation binding
OU809_RS09850	COG1695	Transcriptional regulator
OU809_RS09870	COG0464	growth
OU809_RS09875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OU809_RS09880	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OU809_RS09885	COG0789	Transcriptional regulator
OU809_RS09890	COG0174	glutamine synthetase
OU809_RS09940	COG0490	domain, Protein
OU809_RS09945	COG0475	glutathione-regulated potassium exporter activity
OU809_RS09950	COG1073	alpha beta
OU809_RS09990	COG1309	transcriptional regulator
OU809_RS09995	COG2076	Multidrug Resistance protein
OU809_RS10000	COG2076	Multidrug Resistance protein
OU809_RS10005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS10020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS10025	COG3546	catalase activity
OU809_RS10050	COG1846	Transcriptional regulator
OU809_RS10055	COG0346	lactoylglutathione lyase activity
OU809_RS10060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OU809_RS10065	COG0655	NAD(P)H dehydrogenase (quinone) activity
OU809_RS10090	COG3209	COG3209 Rhs family protein
OU809_RS10095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OU809_RS10100	COG1388	LysM domain
OU809_RS10105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OU809_RS10110	COG4224	UPF0291 protein
OU809_RS10115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OU809_RS10125	COG3763	UPF0154 protein
OU809_RS10135	COG0785	Cytochrome C biogenesis protein
OU809_RS10140	COG2201	protein-glutamate methylesterase activity
OU809_RS10145	COG4846	Membrane protein involved in cytochrome C biogenesis
OU809_RS10155	COG0071	Belongs to the small heat shock protein (HSP20) family
OU809_RS10170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OU809_RS10175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS10195	COG0824	Thioesterase
OU809_RS10215	COG4841	protein insertion into membrane
OU809_RS10220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OU809_RS10225	COG1832	CoA-binding protein
OU809_RS10230	COG0187	DNA topoisomerase II activity
OU809_RS10235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OU809_RS10240	COG1609	Transcriptional regulator
OU809_RS10255	COG2160	L-arabinose isomerase activity
OU809_RS10280	COG1115	amino acid carrier protein
OU809_RS10290	COG2181	nitrate reductase activity
OU809_RS10295	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OU809_RS10300	COG1140	nitrate reductase beta subunit
OU809_RS10305	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OU809_RS10320	COG0535	radical SAM domain protein
OU809_RS10325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OU809_RS10335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OU809_RS10340	COG2223	nitrite transmembrane transporter activity
OU809_RS10360	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
OU809_RS10370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
OU809_RS10380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS10395	COG0477	Major facilitator Superfamily
OU809_RS10400	COG3420	alginic acid biosynthetic process
OU809_RS10405	COG1114	Component of the transport system for branched-chain amino acids
OU809_RS10415	COG1687	branched-chain amino acid
OU809_RS10420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OU809_RS10425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS10450	COG1024	Enoyl-CoA hydratase
OU809_RS10455	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS10460	COG2084	Dehydrogenase
OU809_RS10465	COG1960	acyl-CoA dehydrogenase activity
OU809_RS10470	COG1482	cell wall glycoprotein biosynthetic process
OU809_RS10475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS10475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS10475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS10490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS10490	COG3711	transcriptional antiterminator
OU809_RS10505	COG1725	Transcriptional regulator
OU809_RS10510	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS10515	COG1312	Catalyzes the dehydration of D-mannonate
OU809_RS10530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
OU809_RS10540	COG1609	Transcriptional regulator
OU809_RS10545	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OU809_RS10550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OU809_RS10555	COG0640	Transcriptional regulator
OU809_RS10560	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
OU809_RS10580	COG2404	hydrolase activity, acting on ester bonds
OU809_RS10585	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OU809_RS10595	COG0438	transferase activity, transferring glycosyl groups
OU809_RS10600	COG2027	D-alanyl-D-alanine carboxypeptidase
OU809_RS10620	COG1309	transcriptional regulator
OU809_RS10625	COG1252	NADH dehydrogenase
OU809_RS10635	COG0166	Belongs to the GPI family
OU809_RS10645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OU809_RS10650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OU809_RS10655	COG1024	Enoyl-CoA hydratase
OU809_RS10660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OU809_RS10665	COG0511	ligase activity, forming carbon-carbon bonds
OU809_RS10670	COG0439	Biotin carboxylase
OU809_RS10675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS10675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OU809_RS10680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS10685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS10690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS10695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS10700	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS10705	COG1960	acyl-CoA dehydrogenase activity
OU809_RS10710	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU809_RS10715	COG1733	regulation of RNA biosynthetic process
OU809_RS10720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OU809_RS10725	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OU809_RS10735	COG2323	membrane
OU809_RS10740	COG0306	phosphate transporter
OU809_RS10745	COG0175	sulfate reduction
OU809_RS10750	COG1809	phosphosulfolactate synthase activity
OU809_RS10755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS10760	COG4948	Mandelate Racemase Muconate Lactonizing
OU809_RS10765	COG2814	Major facilitator Superfamily
OU809_RS10770	COG0463	Glycosyl transferase, family 2
OU809_RS10785	COG0493	'glutamate synthase
OU809_RS10790	COG0067	glutamate synthase
OU809_RS10790	COG0069	glutamate synthase activity
OU809_RS10790	COG0070	glutamate synthase
OU809_RS10795	COG0583	DNA-binding transcription factor activity
OU809_RS10825	COG1132	(ABC) transporter
OU809_RS10835	COG0300	oxidoreductase activity
OU809_RS10840	COG0574	Belongs to the PEP-utilizing enzyme family
OU809_RS10840	COG3848	Pyruvate phosphate dikinase
OU809_RS10845	COG0477	Major facilitator Superfamily
OU809_RS10850	COG0243	molybdopterin cofactor binding
OU809_RS10855	COG1846	Transcriptional regulator
OU809_RS10860	COG2814	Major facilitator Superfamily
OU809_RS10865	COG0531	amino acid
OU809_RS10875	COG0531	amino acid
OU809_RS10880	COG0531	amino acid
OU809_RS10885	COG0697	spore germination
OU809_RS10895	COG0488	(ABC) transporter
OU809_RS10900	COG0840	transmembrane signaling receptor activity
OU809_RS10905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU809_RS10910	COG1404	Belongs to the peptidase S8 family
OU809_RS10920	COG1309	transcriptional regulator
OU809_RS10925	COG1846	Transcriptional regulator
OU809_RS10955	COG1309	transcriptional regulator
OU809_RS10960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS10965	COG3708	Transcriptional regulator
OU809_RS10975	COG2378	regulation of single-species biofilm formation
OU809_RS10985	COG0640	Transcriptional regulator
OU809_RS10990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS11000	COG0531	amino acid
OU809_RS11005	COG0741	lytic transglycosylase activity
OU809_RS11010	COG1086	Polysaccharide biosynthesis protein
OU809_RS11025	COG0438	transferase activity, transferring glycosyl groups
OU809_RS11030	COG2322	membrane
OU809_RS11045	COG1619	proteins homologs of microcin C7 resistance protein MccF
OU809_RS11050	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS11055	COG1388	LysM domain
OU809_RS11055	COG3584	3D domain protein
OU809_RS11060	COG0514	ATP-dependent DNA helicase (RecQ)
OU809_RS11090	COG5444	nuclease activity
OU809_RS11095	COG2427	Protein of unknown function (DUF1641)
OU809_RS11100	COG3383	formate dehydrogenase (NAD+) activity
OU809_RS11110	COG5444	nuclease activity
OU809_RS11115	COG0457	Tetratricopeptide repeat
OU809_RS11120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS11135	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OU809_RS11155	COG2350	Protein conserved in bacteria
OU809_RS11175	COG0402	S-adenosylhomocysteine deaminase activity
OU809_RS11190	COG2267	carboxylic ester hydrolase activity
OU809_RS11205	COG1280	lysine exporter protein (LysE YggA)
OU809_RS11210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OU809_RS11220	COG3848	Pyruvate phosphate dikinase
OU809_RS11220	COG0574	Belongs to the PEP-utilizing enzyme family
OU809_RS11240	COG2318	DinB family
OU809_RS11245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OU809_RS11260	COG0156	8-amino-7-oxononanoate synthase activity
OU809_RS11265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU809_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS11285	COG2814	Major facilitator Superfamily
OU809_RS11300	COG1657	PFAM Prenyltransferase squalene oxidase
OU809_RS11305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OU809_RS11315	COG0733	neurotransmitter:sodium symporter activity
OU809_RS11320	COG0385	Bile acid
OU809_RS11325	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU809_RS11330	COG0567	Dehydrogenase, E1 component
OU809_RS11335	COG4548	von Willebrand factor, type A
OU809_RS11340	COG0714	Associated with various cellular activities
OU809_RS11345	COG2032	superoxide dismutase activity
OU809_RS11350	COG0791	NLP P60 protein
OU809_RS11350	COG1388	LysM domain
OU809_RS11355	COG0534	Mate efflux family protein
OU809_RS11360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU809_RS11365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU809_RS11375	COG2962	Rard protein
OU809_RS11385	COG4305	rare lipoprotein A
OU809_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS11400	COG1733	regulation of RNA biosynthetic process
OU809_RS11405	COG0778	Nitroreductase
OU809_RS11410	COG0400	carboxylic ester hydrolase activity
OU809_RS11420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS11425	COG0793	Belongs to the peptidase S41A family
OU809_RS11425	COG3409	Peptidoglycan-binding domain 1 protein
OU809_RS11430	COG2226	methyltransferase
OU809_RS11440	COG1876	peptidase activity
OU809_RS11445	COG0813	purine-nucleoside phosphorylase activity
OU809_RS11450	COG0701	Predicted permease
OU809_RS11470	COG0671	phosphoesterase, PA-phosphatase related
OU809_RS11490	COG4479	Belongs to the UPF0346 family
OU809_RS11500	COG1509	lysine 2,3-aminomutase activity
OU809_RS11505	COG0456	acetyltransferase
OU809_RS11510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU809_RS11515	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OU809_RS11520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OU809_RS11525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OU809_RS11540	COG0456	acetyltransferase
OU809_RS11545	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OU809_RS11550	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OU809_RS11555	COG1846	Transcriptional regulator
OU809_RS11565	COG3706	GGDEF domain
OU809_RS11570	COG0534	Mate efflux family protein
OU809_RS11585	COG4698	Protein conserved in bacteria
OU809_RS11590	COG2755	lipolytic protein G-D-S-L family
OU809_RS11595	COG1999	signal sequence binding
OU809_RS11610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OU809_RS11615	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OU809_RS11620	COG1272	protein, Hemolysin III
OU809_RS11625	COG0204	Acyl-transferase
OU809_RS11630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OU809_RS11635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OU809_RS11645	COG2521	methyltransferase
OU809_RS11645	COG2136	Putative SAM-dependent methyltransferase
OU809_RS11655	COG0129	dihydroxy-acid dehydratase activity
OU809_RS11660	COG1413	lyase activity
OU809_RS11665	COG1418	mRNA catabolic process
OU809_RS11670	COG0386	Belongs to the glutathione peroxidase family
OU809_RS11675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OU809_RS11680	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OU809_RS11685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OU809_RS11695	COG1278	Cold shock
OU809_RS11715	COG0328	RNA-DNA hybrid ribonuclease activity
OU809_RS11720	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OU809_RS11725	COG0328	RNA-DNA hybrid ribonuclease activity
OU809_RS11735	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU809_RS11750	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OU809_RS11760	COG1755	Isoprenylcysteine carboxyl methyltransferase
OU809_RS11765	COG3424	synthase
OU809_RS11775	COG2233	PERMEase
OU809_RS11780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OU809_RS11785	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OU809_RS11790	COG1199	ATP-dependent helicase activity
OU809_RS11815	COG0116	Belongs to the methyltransferase superfamily
OU809_RS11825	COG3599	regulation of cell shape
OU809_RS11830	COG4474	Belongs to the UPF0398 family
OU809_RS11840	COG3359	exonuclease
OU809_RS11845	COG1205	dead DEAH box helicase
OU809_RS11845	COG1111	helicase
OU809_RS11850	COG2190	(PTS) system
OU809_RS11855	COG0071	Belongs to the small heat shock protein (HSP20) family
OU809_RS11890	COG3331	DNA recombination
OU809_RS11895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU809_RS11895	COG4499	WXG100 protein secretion system (Wss), protein YukC
OU809_RS11905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OU809_RS11910	COG3935	DnaD domain protein
OU809_RS11915	COG0017	Asparaginyl-tRNA synthetase
OU809_RS11920	COG0436	Aminotransferase
OU809_RS11925	COG5353	protein conserved in bacteria
OU809_RS11935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OU809_RS11935	COG1199	ATP-dependent helicase activity
OU809_RS11940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OU809_RS11945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OU809_RS11950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OU809_RS11960	COG0617	tRNA 3'-terminal CCA addition
OU809_RS11965	COG0438	transferase activity, transferring glycosyl groups
OU809_RS11970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OU809_RS11975	COG1803	Methylglyoxal synthase
OU809_RS11980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OU809_RS11985	COG1694	Mazg nucleotide pyrophosphohydrolase
OU809_RS11990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS12000	COG4347	Protein of unknown function (DUF1405)
OU809_RS12010	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OU809_RS12010	COG2010	Cytochrome c
OU809_RS12015	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OU809_RS12020	COG0723	plastoquinol--plastocyanin reductase activity
OU809_RS12030	COG5582	Belongs to the UPF0302 family
OU809_RS12035	COG0457	Tetratricopeptide repeat
OU809_RS12040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OU809_RS12045	COG0287	Prephenate dehydrogenase
OU809_RS12050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OU809_RS12055	COG0159	tryptophan synthase activity
OU809_RS12060	COG0133	tryptophan synthase activity
OU809_RS12065	COG0135	phosphoribosylanthranilate isomerase activity
OU809_RS12070	COG0134	indole-3-glycerol-phosphate synthase activity
OU809_RS12075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OU809_RS12080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OU809_RS12085	COG4401	Chorismate mutase type I
OU809_RS12090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OU809_RS12095	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OU809_RS12100	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OU809_RS12105	COG0105	UTP biosynthetic process
OU809_RS12110	COG0142	geranyltranstransferase activity
OU809_RS12115	COG2226	methyltransferase
OU809_RS12120	COG0142	geranyltranstransferase activity
OU809_RS12135	COG0776	regulation of translation
OU809_RS12140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OU809_RS12155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OU809_RS12160	COG1160	GTP binding
OU809_RS12185	COG1304	FMN binding
OU809_RS12190	COG0539	negative regulation of cytoplasmic translation
OU809_RS12195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OU809_RS12205	COG2959	enzyme of heme biosynthesis
OU809_RS12210	COG3409	Peptidoglycan-binding domain 1 protein
OU809_RS12210	COG3773	Cell wall hydrolase
OU809_RS12215	COG2339	peptidase activity
OU809_RS12225	COG0492	ferredoxin-NADP+ reductase activity
OU809_RS12230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OU809_RS12235	COG4862	establishment of competence for transformation
OU809_RS12240	COG1408	metallophosphoesterase
OU809_RS12250	COG1388	LysM domain
OU809_RS12255	COG1266	CAAX protease self-immunity
OU809_RS12260	COG0514	ATP-dependent DNA helicase (RecQ)
OU809_RS12265	COG4955	Helix-turn-helix domain
OU809_RS12270	COG1141	Ferredoxin
OU809_RS12275	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OU809_RS12280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OU809_RS12285	COG0739	heme binding
OU809_RS12295	COG1595	DNA-templated transcription, initiation
OU809_RS12300	COG1316	TRANSCRIPTIONal
OU809_RS12315	COG5002	protein histidine kinase activity
OU809_RS12320	COG0745	RESPONSE REGULATOR receiver
OU809_RS12325	COG5002	protein histidine kinase activity
OU809_RS12330	COG0745	RESPONSE REGULATOR receiver
OU809_RS12335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OU809_RS12340	COG1333	cytochrome c biogenesis protein
OU809_RS12345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS12350	COG1187	pseudouridine synthase activity
OU809_RS12355	COG0700	Nucleoside recognition
OU809_RS12360	COG2715	membrane protein required for spore maturation
OU809_RS12365	COG1686	Belongs to the peptidase S11 family
OU809_RS12375	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OU809_RS12380	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OU809_RS12390	COG1547	Domain of unknown function (DUF309)
OU809_RS12395	COG0456	acetyltransferase
OU809_RS12400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OU809_RS12405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OU809_RS12405	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OU809_RS12410	COG0307	riboflavin synthase, alpha
OU809_RS12415	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OU809_RS12415	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OU809_RS12440	COG0457	Tetratricopeptide repeat
OU809_RS12445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OU809_RS12450	COG4086	secreted protein
OU809_RS12455	COG4195	phage-related replication protein
OU809_RS12460	COG0019	diaminopimelate decarboxylase activity
OU809_RS12470	COG0697	spore germination
OU809_RS12485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OU809_RS12520	COG1686	Belongs to the peptidase S11 family
OU809_RS12525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OU809_RS12530	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OU809_RS12535	COG4974	Belongs to the 'phage' integrase family
OU809_RS12545	COG0735	belongs to the Fur family
OU809_RS12550	COG1300	Membrane
OU809_RS12555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS12565	COG1953	Uracil, thiamine, allantoin
OU809_RS12580	COG2153	protein acetylation
OU809_RS12585	COG1379	DNA repair
OU809_RS12590	COG0494	nUDIX hydrolase
OU809_RS12600	COG1309	transcriptional regulator
OU809_RS12610	COG0667	Aldo Keto reductase
OU809_RS12620	COG1073	alpha beta
OU809_RS12630	COG4918	Iron-sulphur cluster biosynthesis
OU809_RS12640	COG0456	acetyltransferase
OU809_RS12640	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OU809_RS12645	COG2329	Antibiotic biosynthesis monooxygenase
OU809_RS12650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OU809_RS12660	COG0747	negative chemotaxis
OU809_RS12665	COG0601	transmembrane transport
OU809_RS12670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS12675	COG0444	Belongs to the ABC transporter superfamily
OU809_RS12685	COG0534	Mate efflux family protein
OU809_RS12700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OU809_RS12710	COG2211	Major facilitator Superfamily
OU809_RS12715	COG0346	lactoylglutathione lyase activity
OU809_RS12720	COG1072	(Pantothenic acid kinase))
OU809_RS12730	COG3842	ATPase activity
OU809_RS12755	COG2205	protein histidine kinase activity
OU809_RS12760	COG0745	RESPONSE REGULATOR receiver
OU809_RS12780	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OU809_RS12785	COG2814	Major facilitator Superfamily
OU809_RS12795	COG4195	phage-related replication protein
OU809_RS12800	COG0300	oxidoreductase activity
OU809_RS12805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS12810	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OU809_RS12815	COG4187	Peptidase family M20/M25/M40
OU809_RS12820	COG1902	pentaerythritol trinitrate reductase activity
OU809_RS12825	COG0596	Alpha beta hydrolase
OU809_RS12830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OU809_RS12835	COG1234	tRNA 3'-trailer cleavage
OU809_RS12840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OU809_RS12855	COG2358	TRAP transporter, solute receptor (TAXI family
OU809_RS12860	COG2188	Transcriptional regulator
OU809_RS12865	COG2723	6-phospho-beta-galactosidase activity
OU809_RS12870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS12875	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU809_RS12880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS12885	COG1785	Belongs to the alkaline phosphatase family
OU809_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS12895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OU809_RS12900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OU809_RS12910	COG0706	membrane insertase activity
OU809_RS12915	COG2195	Cleaves the N-terminal amino acid of tripeptides
OU809_RS12920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OU809_RS12930	COG4129	membrane
OU809_RS12935	COG1126	abc transporter atp-binding protein
OU809_RS12940	COG0765	amino acid transport
OU809_RS12945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OU809_RS12955	COG1597	lipid kinase activity
OU809_RS12960	COG0508	dehydrogenase complex catalyzes the overall conversion of
OU809_RS12965	COG0022	dehydrogenase e1 component
OU809_RS12970	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OU809_RS12975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OU809_RS12980	COG3426	butyrate kinase activity
OU809_RS12990	COG0280	phosphate acetyltransferase
OU809_RS12995	COG3829	transcription factor binding
OU809_RS12995	COG3290	protein histidine kinase activity
OU809_RS13005	COG0584	glycerophosphoryl diester phosphodiesterase
OU809_RS13010	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU809_RS13030	COG0745	RESPONSE REGULATOR receiver
OU809_RS13035	COG0750	zinc metalloprotease
OU809_RS13040	COG0497	DNA recombination
OU809_RS13045	COG1438	arginine binding
OU809_RS13050	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OU809_RS13055	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OU809_RS13060	COG0142	geranyltranstransferase activity
OU809_RS13065	COG1722	exodeoxyribonuclease VII activity
OU809_RS13070	COG1570	exodeoxyribonuclease VII activity
OU809_RS13075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OU809_RS13080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OU809_RS13085	COG1302	Protein conserved in bacteria
OU809_RS13090	COG0439	Biotin carboxylase
OU809_RS13095	COG0511	ligase activity, forming carbon-carbon bonds
OU809_RS13135	COG3854	ATPases associated with a variety of cellular activities
OU809_RS13145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OU809_RS13150	COG0006	proline dipeptidase activity
OU809_RS13155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OU809_RS13165	COG3872	metal-dependent enzyme
OU809_RS13175	COG1752	Esterase of the alpha-beta hydrolase superfamily
OU809_RS13180	COG1321	iron dependent repressor
OU809_RS13185	COG0095	Lipoate-protein ligase
OU809_RS13190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU809_RS13195	COG2113	Glycine betaine
OU809_RS13200	COG4176	ABC-type proline glycine betaine transport system permease component
OU809_RS13205	COG0517	IMP dehydrogenase activity
OU809_RS13205	COG4175	Glycine betaine
OU809_RS13210	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OU809_RS13215	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OU809_RS13220	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OU809_RS13225	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OU809_RS13250	COG0681	Belongs to the peptidase S26 family
OU809_RS13275	COG4940	Competence protein ComGF
OU809_RS13285	COG4970	Tfp pilus assembly protein FimT
OU809_RS13290	COG4537	Required for transformation and DNA binding
OU809_RS13295	COG1459	type II secretion system
OU809_RS13300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OU809_RS13305	COG1366	Belongs to the anti-sigma-factor antagonist family
OU809_RS13315	COG1393	Belongs to the ArsC family
OU809_RS13325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS13335	COG0011	TIGRFAM Protein of
OU809_RS13345	COG2866	Carboxypeptidase
OU809_RS13350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS13355	COG1368	sulfuric ester hydrolase activity
OU809_RS13360	COG1940	carbohydrate kinase activity
OU809_RS13365	COG4483	Protein conserved in bacteria
OU809_RS13370	COG0697	spore germination
OU809_RS13375	COG0457	Tetratricopeptide repeat
OU809_RS13375	COG0705	Rhomboid family
OU809_RS13385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OU809_RS13390	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OU809_RS13395	COG0438	transferase activity, transferring glycosyl groups
OU809_RS13410	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OU809_RS13455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OU809_RS13460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OU809_RS13465	COG0581	inorganic phosphate transmembrane transporter activity
OU809_RS13470	COG0573	inorganic phosphate transmembrane transporter activity
OU809_RS13475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OU809_RS13480	COG0768	penicillin binding
OU809_RS13485	COG0477	Major facilitator Superfamily
OU809_RS13490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OU809_RS13495	COG2839	Protein conserved in bacteria
OU809_RS13500	COG5521	maltodextrose utilization protein MalA
OU809_RS13505	COG1388	LysM domain
OU809_RS13510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OU809_RS13515	COG4709	membrane
OU809_RS13520	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OU809_RS13525	COG0735	belongs to the Fur family
OU809_RS13530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OU809_RS13535	COG1121	(ABC) transporter
OU809_RS13540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS13550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OU809_RS13555	COG0513	Belongs to the DEAD box helicase family
OU809_RS13565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OU809_RS13570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OU809_RS13575	COG2384	SAM-dependent methyltransferase
OU809_RS13600	COG5444	nuclease activity
OU809_RS13615	COG2010	Cytochrome c
OU809_RS13620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OU809_RS13625	COG0358	DNA primase activity
OU809_RS13630	COG1671	Belongs to the UPF0178 family
OU809_RS13635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OU809_RS13640	COG0517	IMP dehydrogenase activity
OU809_RS13645	COG0751	glycine-tRNA ligase activity
OU809_RS13650	COG0752	glycyl-tRNA synthetase alpha subunit
OU809_RS13655	COG1381	Involved in DNA repair and RecF pathway recombination
OU809_RS13665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OU809_RS13670	COG0295	cytidine deaminase activity
OU809_RS13675	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OU809_RS13680	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OU809_RS13685	COG1480	7TM receptor with intracellular HD hydrolase
OU809_RS13690	COG1702	phosphate starvation-inducible protein PhoH
OU809_RS13695	COG0561	phosphatase activity
OU809_RS13710	COG4864	UPF0365 protein
OU809_RS13715	COG1030	water channel activity
OU809_RS13720	COG1610	YqeY-like protein
OU809_RS13725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OU809_RS13730	COG1283	sodium-dependent phosphate transmembrane transporter activity
OU809_RS13735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OU809_RS13740	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OU809_RS13745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OU809_RS13750	COG2264	protein methyltransferase activity
OU809_RS13755	COG0484	heat shock protein binding
OU809_RS13760	COG0443	Heat shock 70 kDa protein
OU809_RS13765	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OU809_RS13770	COG1420	regulation of RNA biosynthetic process
OU809_RS13775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OU809_RS13780	COG0481	GTPase activity
OU809_RS13790	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU809_RS13795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OU809_RS13800	COG0268	Binds directly to 16S ribosomal RNA
OU809_RS13815	COG1733	regulation of RNA biosynthetic process
OU809_RS13820	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU809_RS13825	COG1466	dna polymerase III delta subunit
OU809_RS13835	COG0658	competence protein
OU809_RS13835	COG2333	competence protein COMEC
OU809_RS13840	COG2131	deaminase
OU809_RS13845	COG1555	photosystem II stabilization
OU809_RS13845	COG1596	polysaccharide export
OU809_RS13850	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OU809_RS13855	COG2226	methyltransferase
OU809_RS13860	COG0799	negative regulation of ribosome biogenesis
OU809_RS13865	COG1713	HD superfamily hydrolase involved in NAD metabolism
OU809_RS13870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OU809_RS13875	COG1534	Rna-binding protein
OU809_RS13880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OU809_RS13885	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OU809_RS13890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OU809_RS13905	COG2755	lipolytic protein G-D-S-L family
OU809_RS13915	COG5609	conserved protein (DUF2294)
OU809_RS13920	COG3383	formate dehydrogenase (NAD+) activity
OU809_RS13925	COG2427	Protein of unknown function (DUF1641)
OU809_RS13960	COG3223	Belongs to the PsiE family
OU809_RS13965	COG0642	Histidine kinase
OU809_RS13965	COG5002	protein histidine kinase activity
OU809_RS13970	COG0745	RESPONSE REGULATOR receiver
OU809_RS13975	COG2311	Membrane
OU809_RS13980	COG0454	-acetyltransferase
OU809_RS14000	COG1247	-acetyltransferase
OU809_RS14010	COG0561	phosphatase activity
OU809_RS14015	COG1486	melibiose metabolic process
OU809_RS14030	COG0789	Transcriptional regulator
OU809_RS14030	COG4978	Transcriptional regulator
OU809_RS14045	COG2828	Protein conserved in bacteria
OU809_RS14055	COG2181	nitrate reductase activity
OU809_RS14060	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OU809_RS14065	COG1140	nitrate reductase beta subunit
OU809_RS14070	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OU809_RS14075	COG2223	nitrite transmembrane transporter activity
OU809_RS14100	COG2197	response regulator
OU809_RS14105	COG4585	Histidine kinase
OU809_RS14110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS14115	COG0730	response to heat
OU809_RS14120	COG0425	Belongs to the sulfur carrier protein TusA family
OU809_RS14125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS14125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU809_RS14130	COG0425	Belongs to the sulfur carrier protein TusA family
OU809_RS14130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU809_RS14135	COG2210	Belongs to the sulfur carrier protein TusA family
OU809_RS14140	COG1937	Protein conserved in bacteria
OU809_RS14165	COG1942	4-Oxalocrotonate Tautomerase
OU809_RS14170	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OU809_RS14175	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OU809_RS14180	COG1733	regulation of RNA biosynthetic process
OU809_RS14185	COG3239	Fatty acid desaturase
OU809_RS14190	COG4585	Histidine kinase
OU809_RS14195	COG2197	response regulator
OU809_RS14200	COG0492	ferredoxin-NADP+ reductase activity
OU809_RS14205	COG0747	negative chemotaxis
OU809_RS14210	COG0601	transmembrane transport
OU809_RS14215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OU809_RS14220	COG0444	Belongs to the ABC transporter superfamily
OU809_RS14225	COG4608	Belongs to the ABC transporter superfamily
OU809_RS14245	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS14255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OU809_RS14270	COG2124	cytochrome p450
OU809_RS14275	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS14295	COG1621	beta-fructofuranosidase activity
OU809_RS14300	COG3716	PTS system mannose fructose sorbose family IID component
OU809_RS14305	COG3715	PTS system
OU809_RS14310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS14315	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS14320	COG3933	PFAM sigma-54 factor interaction domain-containing protein
OU809_RS14320	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OU809_RS14340	COG2169	Transcriptional regulator
OU809_RS14350	COG2205	protein histidine kinase activity
OU809_RS14360	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OU809_RS14365	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OU809_RS14370	COG0656	L-ascorbic acid biosynthetic process
OU809_RS14375	COG2814	Major facilitator Superfamily
OU809_RS14380	COG1733	regulation of RNA biosynthetic process
OU809_RS14385	COG3340	Belongs to the peptidase S51 family
OU809_RS14390	COG1587	Uroporphyrinogen-III synthase
OU809_RS14405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS14410	COG0583	DNA-binding transcription factor activity
OU809_RS14415	COG2814	Major facilitator Superfamily
OU809_RS14425	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OU809_RS14425	COG2124	cytochrome p450
OU809_RS14430	COG1309	transcriptional regulator
OU809_RS14435	COG1404	Belongs to the peptidase S8 family
OU809_RS14440	COG2226	methyltransferase
OU809_RS14465	COG0626	cystathionine gamma-synthase activity
OU809_RS14470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU809_RS14475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OU809_RS14480	COG2226	methyltransferase
OU809_RS14495	COG0768	penicillin binding
OU809_RS14500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OU809_RS14505	COG0572	uridine kinase
OU809_RS14510	COG0826	peptidase U32
OU809_RS14515	COG0826	peptidase U32
OU809_RS14520	COG4122	O-methyltransferase activity
OU809_RS14525	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OU809_RS14530	COG3906	Belongs to the UPF0473 family
OU809_RS14535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OU809_RS14540	COG4472	Bacterial protein of unknown function (DUF965)
OU809_RS14545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OU809_RS14550	COG0628	permease
OU809_RS14565	COG3881	PFAM PRC-barrel domain
OU809_RS14570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OU809_RS14575	COG0457	Tetratricopeptide repeat
OU809_RS14580	COG0482	sulfurtransferase activity
OU809_RS14585	COG1104	cysteine desulfurase activity
OU809_RS14590	COG1959	2 iron, 2 sulfur cluster binding
OU809_RS14595	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OU809_RS14600	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OU809_RS14610	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OU809_RS14615	COG0124	histidyl-tRNA synthetase
OU809_RS14625	COG4991	sh3 domain protein
OU809_RS14625	COG3103	Sh3 type 3 domain protein
OU809_RS14625	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU809_RS14630	COG1490	D-aminoacyl-tRNA deacylase activity
OU809_RS14635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OU809_RS14640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OU809_RS14645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OU809_RS14645	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OU809_RS14650	COG5416	Lipopolysaccharide assembly protein A domain
OU809_RS14655	COG0490	domain, Protein
OU809_RS14660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OU809_RS14660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OU809_RS14670	COG2244	polysaccharide biosynthetic process
OU809_RS14675	COG2323	membrane
OU809_RS14685	COG1862	Preprotein translocase
OU809_RS14690	COG0343	queuine tRNA-ribosyltransferase activity
OU809_RS14695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OU809_RS14705	COG2255	four-way junction helicase activity
OU809_RS14710	COG0632	four-way junction helicase activity
OU809_RS14720	COG2112	serine threonine protein kinase
OU809_RS14740	COG0642	Histidine kinase
OU809_RS14745	COG0745	RESPONSE REGULATOR receiver
OU809_RS14755	COG2318	DinB family
OU809_RS14760	COG4195	phage-related replication protein
OU809_RS14775	COG0217	transcriptional regulatory protein
OU809_RS14785	COG1388	LysM domain
OU809_RS14790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OU809_RS14795	COG0157	Belongs to the NadC ModD family
OU809_RS14800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OU809_RS14805	COG1104	cysteine desulfurase activity
OU809_RS14810	COG1827	regulation of RNA biosynthetic process
OU809_RS14815	COG0077	Prephenate dehydratase
OU809_RS14820	COG4492	Belongs to the UPF0735 family
OU809_RS14825	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OU809_RS14830	COG3290	protein histidine kinase activity
OU809_RS14835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OU809_RS14840	COG2868	ribosomal protein
OU809_RS14845	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OU809_RS14850	COG1994	Peptidase M50
OU809_RS14855	COG0739	heme binding
OU809_RS14860	COG3832	glyoxalase III activity
OU809_RS14865	COG0640	Transcriptional regulator
OU809_RS14870	COG2894	cell division
OU809_RS14875	COG0850	regulation of cytokinetic process
OU809_RS14880	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OU809_RS14890	COG1077	Cell shape determining protein MreB Mrl
OU809_RS14895	COG2003	Belongs to the UPF0758 family
OU809_RS14900	COG0424	maF-like protein
OU809_RS14910	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OU809_RS14915	COG0285	dihydrofolate synthase activity
OU809_RS14920	COG0525	valine-tRNA ligase activity
OU809_RS14930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OU809_RS14935	COG1388	LysM domain
OU809_RS14940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OU809_RS14945	COG0113	porphobilinogen synthase activity
OU809_RS14950	COG1587	Uroporphyrinogen-III synthase
OU809_RS14955	COG0181	hydroxymethylbilane synthase activity
OU809_RS14960	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OU809_RS14965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OU809_RS14975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OU809_RS14980	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OU809_RS14985	COG0470	DNA polymerase III
OU809_RS14985	COG1067	ATP-dependent peptidase activity
OU809_RS14990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OU809_RS14995	COG0544	peptidyl-prolyl cis-trans isomerase activity
OU809_RS15000	COG0457	Tetratricopeptide repeat
OU809_RS15000	COG1477	protein flavinylation
OU809_RS15005	COG0066	3-isopropylmalate dehydratase activity
OU809_RS15010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OU809_RS15015	COG0473	3-isopropylmalate dehydrogenase activity
OU809_RS15020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OU809_RS15025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OU809_RS15030	COG0440	acetolactate synthase activity
OU809_RS15035	COG0028	Belongs to the TPP enzyme family
OU809_RS15040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU809_RS15050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OU809_RS15070	COG0622	Phosphoesterase
OU809_RS15075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OU809_RS15080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OU809_RS15085	COG5401	PFAM Sporulation and spore germination
OU809_RS15090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OU809_RS15095	COG1846	Transcriptional regulator
OU809_RS15100	COG2197	response regulator
OU809_RS15105	COG4221	oxidoreductase activity
OU809_RS15110	COG0824	Thioesterase
OU809_RS15115	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OU809_RS15120	COG1053	succinate dehydrogenase
OU809_RS15125	COG2009	succinate dehydrogenase
OU809_RS15130	COG1719	4-vinyl reductase, 4VR
OU809_RS15135	COG0527	aspartate kinase activity
OU809_RS15140	COG0322	excinuclease ABC activity
OU809_RS15145	COG3118	belongs to the thioredoxin family
OU809_RS15150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OU809_RS15155	COG2086	electron transfer activity
OU809_RS15160	COG1024	Enoyl-CoA hydratase
OU809_RS15165	COG1309	transcriptional regulator
OU809_RS15170	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS15175	COG3766	membrane
OU809_RS15180	COG1193	negative regulation of DNA recombination
OU809_RS15185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OU809_RS15185	COG1796	DNA polymerase
OU809_RS15190	COG1286	toxin biosynthetic process
OU809_RS15195	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OU809_RS15200	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OU809_RS15215	COG0072	phenylalanine-tRNA ligase activity
OU809_RS15215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU809_RS15220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OU809_RS15225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OU809_RS15235	COG1966	Carbon starvation protein
OU809_RS15240	COG1309	transcriptional regulator
OU809_RS15245	COG3402	PFAM membrane-flanked domain
OU809_RS15265	COG0395	ABC-type sugar transport system, permease component
OU809_RS15270	COG1175	transmembrane transport
OU809_RS15275	COG1653	transport
OU809_RS15280	COG0371	Dehydrogenase
OU809_RS15285	COG0235	Class ii aldolase
OU809_RS15290	COG1069	ribulokinase activity
OU809_RS15295	COG2160	L-arabinose isomerase activity
OU809_RS15300	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS15305	COG1363	Peptidase, m42
OU809_RS15315	COG3326	Membrane
OU809_RS15320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OU809_RS15325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OU809_RS15330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OU809_RS15335	COG1346	cytolysis
OU809_RS15345	COG3540	Alkaline phosphatase
OU809_RS15350	COG3279	Response regulator of the LytR AlgR family
OU809_RS15355	COG3275	phosphorelay sensor kinase activity
OU809_RS15365	COG1011	Hydrolase
OU809_RS15370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OU809_RS15380	COG0398	Pfam SNARE associated Golgi protein
OU809_RS15385	COG1484	DNA-dependent DNA replication
OU809_RS15390	COG3611	Membrane attachment protein
OU809_RS15395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OU809_RS15405	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OU809_RS15410	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OU809_RS15415	COG3866	Pectate lyase
OU809_RS15420	COG0237	dephospho-CoA kinase activity
OU809_RS15425	COG1971	Probably functions as a manganese efflux pump
OU809_RS15430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OU809_RS15435	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU809_RS15435	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OU809_RS15440	COG5002	protein histidine kinase activity
OU809_RS15445	COG0745	RESPONSE REGULATOR receiver
OU809_RS15450	COG0039	L-malate dehydrogenase activity
OU809_RS15455	COG0538	isocitrate dehydrogenase activity
OU809_RS15460	COG0372	Belongs to the citrate synthase family
OU809_RS15465	COG2273	Hydrolase Family 16
OU809_RS15475	COG2707	UPF0756 membrane protein
OU809_RS15480	COG0628	permease
OU809_RS15485	COG3030	protein affecting phage T7 exclusion by the F plasmid
OU809_RS15495	COG0205	6-phosphofructokinase activity
OU809_RS15500	COG0825	malonyl-CoA metabolic process
OU809_RS15505	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OU809_RS15510	COG0281	malic enzyme
OU809_RS15515	COG0587	DNA-directed DNA polymerase activity
OU809_RS15535	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OU809_RS15545	COG4109	DRTGG domain
OU809_RS15550	COG1695	Transcriptional regulator
OU809_RS15555	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OU809_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS15570	COG0165	Argininosuccinate lyase
OU809_RS15575	COG0137	argininosuccinate synthase activity
OU809_RS15580	COG0521	Mo-molybdopterin cofactor biosynthetic process
OU809_RS15585	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OU809_RS15590	COG0827	DNA restriction-modification system
OU809_RS15595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OU809_RS15600	COG3874	Sporulation protein YtfJ
OU809_RS15610	COG1714	RDD family
OU809_RS15615	COG0616	signal peptide processing
OU809_RS15620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OU809_RS15630	COG1846	Transcriptional regulator
OU809_RS15635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OU809_RS15645	COG0301	tRNA thio-modification
OU809_RS15650	COG1104	cysteine desulfurase activity
OU809_RS15655	COG1114	Component of the transport system for branched-chain amino acids
OU809_RS15660	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OU809_RS15665	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OU809_RS15670	COG1309	transcriptional regulator
OU809_RS15675	COG1956	GAF domain-containing protein
OU809_RS15680	COG2199	diguanylate cyclase activity
OU809_RS15680	COG2203	Gaf domain
OU809_RS15685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OU809_RS15705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OU809_RS15710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OU809_RS15715	COG0454	-acetyltransferase
OU809_RS15720	COG0517	IMP dehydrogenase activity
OU809_RS15725	COG0123	including yeast histone deacetylase and acetoin utilization protein
OU809_RS15730	COG1360	Flagellar Motor Protein
OU809_RS15735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OU809_RS15740	COG1609	Transcriptional regulator
OU809_RS15745	COG1605	Chorismate mutase
OU809_RS15745	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OU809_RS15755	COG3118	belongs to the thioredoxin family
OU809_RS15760	COG4980	gas vesicle protein
OU809_RS15765	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OU809_RS15770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OU809_RS15775	COG1674	ftsk spoiiie
OU809_RS15780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OU809_RS15785	COG4848	Belongs to the UPF0354 family
OU809_RS15790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS15800	COG1363	Peptidase, m42
OU809_RS15805	COG5584	Small secreted protein
OU809_RS15810	COG0281	malic enzyme
OU809_RS15815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OU809_RS15820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OU809_RS15830	COG0510	thiamine kinase activity
OU809_RS15835	COG1523	belongs to the glycosyl hydrolase 13 family
OU809_RS15840	COG1597	lipid kinase activity
OU809_RS15850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OU809_RS15855	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OU809_RS15870	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OU809_RS15875	COG2252	PERMEase
OU809_RS15880	COG4473	ABC transporter
OU809_RS15885	COG1131	(ABC) transporter
OU809_RS15890	COG1349	DNA-binding transcription factor activity
OU809_RS15895	COG1187	pseudouridine synthase activity
OU809_RS15900	COG2244	polysaccharide biosynthetic process
OU809_RS15905	COG2081	HI0933 family
OU809_RS15910	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OU809_RS15920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU809_RS15930	COG0457	Tetratricopeptide repeat
OU809_RS15940	COG5578	integral membrane protein
OU809_RS15945	COG0673	inositol 2-dehydrogenase activity
OU809_RS15950	COG1653	transport
OU809_RS15955	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
OU809_RS15960	COG4209	transmembrane transport
OU809_RS15965	COG2207	Transcriptional regulator
OU809_RS15970	COG1653	transport
OU809_RS15975	COG0395	ABC-type sugar transport system, permease component
OU809_RS15980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU809_RS15985	COG1073	alpha beta
OU809_RS15995	COG0583	DNA-binding transcription factor activity
OU809_RS16000	COG0346	lactoylglutathione lyase activity
OU809_RS16005	COG0495	leucyl-tRNA aminoacylation
OU809_RS16015	COG2814	Major facilitator Superfamily
OU809_RS16020	COG1464	Belongs to the NlpA lipoprotein family
OU809_RS16025	COG2433	Pfam Transposase IS66
OU809_RS16025	COG2433	Pfam Transposase IS66
OU809_RS16030	COG0577	efflux transmembrane transporter activity
OU809_RS16035	COG1136	(ABC) transporter
OU809_RS16045	COG1131	(ABC) transporter
OU809_RS16050	COG1725	Transcriptional regulator
OU809_RS16065	COG1242	4 iron, 4 sulfur cluster binding
OU809_RS16070	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OU809_RS16075	COG1301	dicarboxylic acid transport
OU809_RS16085	COG2267	carboxylic ester hydrolase activity
OU809_RS16090	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OU809_RS16095	COG0671	phosphoesterase, PA-phosphatase related
OU809_RS16100	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OU809_RS16100	COG0438	transferase activity, transferring glycosyl groups
OU809_RS16105	COG0367	asparagine synthase
OU809_RS16110	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OU809_RS16115	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OU809_RS16120	COG1301	dicarboxylic acid transport
OU809_RS16130	COG1506	peptidase
OU809_RS16135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OU809_RS16140	COG1116	anion transmembrane transporter activity
OU809_RS16145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OU809_RS16150	COG0494	nUDIX hydrolase
OU809_RS16160	COG4824	toxin secretion phage lysis holin
OU809_RS16165	COG0783	Belongs to the Dps family
OU809_RS16180	COG1854	S-ribosylhomocysteine lyase activity
OU809_RS16185	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OU809_RS16190	COG0288	reversible hydration of carbon dioxide
OU809_RS16195	COG0523	cobalamin synthesis protein
OU809_RS16200	COG0803	Belongs to the bacterial solute-binding protein 9 family
OU809_RS16205	COG0254	rRNA binding
OU809_RS16210	COG1271	oxidase subunit
OU809_RS16215	COG1294	oxidase, subunit
OU809_RS16230	COG4948	Mandelate Racemase Muconate Lactonizing
OU809_RS16235	COG0318	PFAM AMP-dependent synthetase and ligase
OU809_RS16240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OU809_RS16245	COG0596	Alpha beta hydrolase
OU809_RS16250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OU809_RS16255	COG1169	isochorismate synthase
OU809_RS16260	COG1575	Belongs to the MenA family. Type 1 subfamily
OU809_RS16265	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OU809_RS16270	COG0058	SHG alpha-glucan phosphorylase activity
OU809_RS16275	COG0297	glycogen (starch) synthase activity
OU809_RS16280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OU809_RS16285	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OU809_RS16290	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OU809_RS16410	COG1609	Transcriptional regulator
OU809_RS16415	COG3859	Proton-coupled thiamine transporter YuaJ
OU809_RS16420	COG3764	Sortase (surface protein transpeptidase)
OU809_RS16435	COG0457	Tetratricopeptide repeat
OU809_RS16445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OU809_RS16450	COG0569	domain protein
OU809_RS16455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OU809_RS16465	COG2318	DinB family
OU809_RS16475	COG1454	alcohol dehydrogenase
OU809_RS16480	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS16485	COG1510	regulation of RNA biosynthetic process
OU809_RS16495	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OU809_RS16500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OU809_RS16505	COG2140	Oxalate decarboxylase
OU809_RS16515	COG1397	ADP-ribosylglycohydrolase
OU809_RS16570	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
OU809_RS16585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OU809_RS16590	COG0726	polysaccharide deacetylase
OU809_RS16595	COG1408	metallophosphoesterase
OU809_RS16600	COG1968	undecaprenyl-diphosphatase activity
OU809_RS16605	COG0628	permease
OU809_RS16610	COG0673	inositol 2-dehydrogenase activity
OU809_RS16615	COG0693	protein deglycase activity
OU809_RS16620	COG0840	transmembrane signaling receptor activity
OU809_RS16625	COG0840	transmembrane signaling receptor activity
OU809_RS16630	COG0840	transmembrane signaling receptor activity
OU809_RS16640	COG2070	2-Nitropropane dioxygenase
OU809_RS16645	COG0432	Pfam Uncharacterised protein family UPF0047
OU809_RS16650	COG0366	Alpha amylase catalytic
OU809_RS16665	COG5297	Belongs to the glycosyl hydrolase family 6
OU809_RS16670	COG1253	flavin adenine dinucleotide binding
OU809_RS16675	COG2738	Putative neutral zinc metallopeptidase
OU809_RS16690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OU809_RS16700	COG2323	membrane
OU809_RS16705	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OU809_RS16715	COG0166	Belongs to the GPI family
OU809_RS16720	COG1979	alcohol dehydrogenase
OU809_RS16725	COG2155	Conserved Protein
OU809_RS16730	COG1098	S1 RNA binding domain
OU809_RS16735	COG0436	Aminotransferase
OU809_RS16740	COG1522	sequence-specific DNA binding
OU809_RS16745	COG2267	carboxylic ester hydrolase activity
OU809_RS16765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OU809_RS16780	COG5018	Exonuclease
OU809_RS16785	COG2814	Major facilitator Superfamily
OU809_RS16790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU809_RS16795	COG3011	Protein conserved in bacteria
OU809_RS16805	COG3290	protein histidine kinase activity
OU809_RS16810	COG4565	transcriptional regulatory protein
OU809_RS16815	COG1183	phosphatidylcholine synthase activity
OU809_RS16820	COG0586	Pfam SNARE associated Golgi protein
OU809_RS16825	COG0688	phosphatidylethanolamine metabolic process
OU809_RS16830	COG3493	citrate carrier protein
OU809_RS16840	COG2111	Na H antiporter
OU809_RS16840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OU809_RS16845	COG2111	Na H antiporter
OU809_RS16850	COG1006	Multisubunit Na H antiporter MnhC subunit
OU809_RS16855	COG0651	ATP synthesis coupled electron transport
OU809_RS16860	COG1863	multisubunit Na H antiporter MnhE subunit
OU809_RS16865	COG2212	antiporter activity
OU809_RS16870	COG1320	monovalent cation:proton antiporter activity
OU809_RS16875	COG2050	protein possibly involved in aromatic compounds catabolism
OU809_RS16880	COG2197	response regulator
OU809_RS16885	COG4585	Histidine kinase
OU809_RS16910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OU809_RS16915	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OU809_RS16920	COG1335	isochorismatase
OU809_RS16925	COG5506	Protein of unknown function (DUF1694)
OU809_RS16940	COG0628	permease
OU809_RS16945	COG1959	2 iron, 2 sulfur cluster binding
OU809_RS16950	COG0657	acetylesterase activity
OU809_RS16960	COG1418	mRNA catabolic process
OU809_RS16965	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS16980	COG1511	domain protein
OU809_RS16985	COG1674	ftsk spoiiie
OU809_RS16985	COG0433	COG0433 Predicted ATPase
OU809_RS16990	COG4499	WXG100 protein secretion system (Wss), protein YukC
OU809_RS16995	COG5417	Belongs to the EsaB family
OU809_RS17000	COG4842	Belongs to the WXG100 family
OU809_RS17005	COG1115	amino acid carrier protein
OU809_RS17010	COG2508	Transcriptional regulator
OU809_RS17010	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OU809_RS17015	COG0686	Belongs to the AlaDH PNT family
OU809_RS17025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OU809_RS17030	COG1268	BioY protein
OU809_RS17035	COG2056	Na+-H+ antiporter family
OU809_RS17040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OU809_RS17045	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OU809_RS17050	COG3584	3D domain protein
OU809_RS17065	COG1252	NADH dehydrogenase
OU809_RS17070	COG0492	ferredoxin-NADP+ reductase activity
OU809_RS17085	COG0454	-acetyltransferase
OU809_RS17090	COG0316	Belongs to the HesB IscA family
OU809_RS17095	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OU809_RS17100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU809_RS17105	COG4844	belongs to the
OU809_RS17110	COG1252	NADH dehydrogenase
OU809_RS17115	COG2323	membrane
OU809_RS17120	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OU809_RS17125	COG5646	InterPro IPR014922
OU809_RS17140	COG0457	Tetratricopeptide repeat
OU809_RS17145	COG3479	Phenolic acid decarboxylase
OU809_RS17155	COG4837	Protein of unknown function (DUF1462)
OU809_RS17165	COG0823	Involved in the tonB-independent uptake of proteins
OU809_RS17165	COG1506	peptidase
OU809_RS17165	COG4946	Tricorn protease homolog
OU809_RS17170	COG0083	homoserine kinase activity
OU809_RS17175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OU809_RS17180	COG0460	homoserine dehydrogenase
OU809_RS17185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU809_RS17190	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OU809_RS17195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OU809_RS17200	COG0647	UMP catabolic process
OU809_RS17205	COG2445	Protein of unknown function DUF86
OU809_RS17210	COG4470	Protein conserved in bacteria
OU809_RS17225	COG0739	heme binding
OU809_RS17235	COG0733	neurotransmitter:sodium symporter activity
OU809_RS17245	COG3377	Domain of unknown function (DUF1805)
OU809_RS17250	COG0737	Belongs to the 5'-nucleotidase family
OU809_RS17255	COG0730	response to heat
OU809_RS17260	COG1801	Protein of unknown function DUF72
OU809_RS17270	COG3226	Transcriptional regulator
OU809_RS17280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OU809_RS17285	COG2508	Transcriptional regulator
OU809_RS17290	COG2814	Major facilitator Superfamily
OU809_RS17295	COG1288	antiporter activity
OU809_RS17300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OU809_RS17305	COG2356	endonuclease I
OU809_RS17315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OU809_RS17330	COG0457	Tetratricopeptide repeat
OU809_RS17340	COG0719	Fe-S assembly protein
OU809_RS17345	COG0822	iron-sulfur transferase activity
OU809_RS17350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OU809_RS17355	COG0719	Fe-S assembly protein
OU809_RS17360	COG0396	ATPase activity
OU809_RS17370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OU809_RS17375	COG1464	Belongs to the NlpA lipoprotein family
OU809_RS17380	COG2011	ABC-type metal ion transport system permease component
OU809_RS17385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OU809_RS17395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OU809_RS17400	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OU809_RS17410	COG0509	glycine decarboxylation via glycine cleavage system
OU809_RS17415	COG1393	Belongs to the ArsC family
OU809_RS17420	COG1960	acyl-CoA dehydrogenase activity
OU809_RS17425	COG0183	Belongs to the thiolase family
OU809_RS17430	COG1024	Enoyl-CoA hydratase
OU809_RS17430	COG1250	3-hydroxyacyl-CoA dehydrogenase
OU809_RS17445	COG5577	PFAM Coat F domain
OU809_RS17460	COG1120	ATPase activity
OU809_RS17465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS17470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS17475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS17490	COG1686	Belongs to the peptidase S11 family
OU809_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS17500	COG0783	Belongs to the Dps family
OU809_RS17505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU809_RS17510	COG0745	RESPONSE REGULATOR receiver
OU809_RS17515	COG2205	protein histidine kinase activity
OU809_RS17515	COG2770	Histidine kinase
OU809_RS17525	COG1309	transcriptional regulator
OU809_RS17530	COG0114	fumarate hydratase activity
OU809_RS17540	COG0697	spore germination
OU809_RS17545	COG0814	amino acid
OU809_RS17560	COG2197	response regulator
OU809_RS17565	COG4585	Histidine kinase
OU809_RS17570	COG4758	membrane
OU809_RS17575	COG3595	metallopeptidase activity
OU809_RS17580	COG1842	Phage shock protein A
OU809_RS17585	COG4758	membrane
OU809_RS17590	COG4677	pectinesterase activity
OU809_RS17595	COG2096	Adenosyltransferase
OU809_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS17620	COG1454	alcohol dehydrogenase
OU809_RS17625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OU809_RS17630	COG1120	ATPase activity
OU809_RS17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS17640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS17645	COG1802	Transcriptional regulator
OU809_RS17650	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS17655	COG2258	MOSC domain
OU809_RS17660	COG0583	DNA-binding transcription factor activity
OU809_RS17670	COG2721	sulfolactate sulfo-lyase activity
OU809_RS17675	COG0246	Mannitol dehydrogenase
OU809_RS17680	COG1609	Transcriptional regulator
OU809_RS17685	COG2211	Major facilitator Superfamily
OU809_RS17690	COG1904	glucuronate isomerase
OU809_RS17695	COG2205	protein histidine kinase activity
OU809_RS17700	COG0745	RESPONSE REGULATOR receiver
OU809_RS17705	COG1120	ATPase activity
OU809_RS17710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS17715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS17720	COG0531	amino acid
OU809_RS17730	COG1988	membrane-bound metal-dependent
OU809_RS17735	COG1368	sulfuric ester hydrolase activity
OU809_RS17740	COG2814	Major facilitator Superfamily
OU809_RS17745	COG0656	L-ascorbic acid biosynthetic process
OU809_RS17750	COG1940	carbohydrate kinase activity
OU809_RS17755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OU809_RS17765	COG0596	Alpha beta hydrolase
OU809_RS17770	COG3973	AAA domain
OU809_RS17775	COG2860	membrane
OU809_RS17780	COG0456	acetyltransferase
OU809_RS17780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OU809_RS17785	COG0456	acetyltransferase
OU809_RS17790	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OU809_RS17795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OU809_RS17800	COG2217	Heavy metal translocating P-type atpase
OU809_RS17805	COG1653	transport
OU809_RS17810	COG1175	transmembrane transport
OU809_RS17815	COG0395	ABC-type sugar transport system, permease component
OU809_RS17820	COG1501	Belongs to the glycosyl hydrolase 31 family
OU809_RS17825	COG1472	Belongs to the glycosyl hydrolase 3 family
OU809_RS17830	COG1121	(ABC) transporter
OU809_RS17835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OU809_RS17840	COG0803	Belongs to the bacterial solute-binding protein 9 family
OU809_RS17860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS17860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OU809_RS17860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS17865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS17880	COG2217	Heavy metal translocating P-type atpase
OU809_RS17885	COG2608	mercury ion transmembrane transporter activity
OU809_RS17890	COG1937	Protein conserved in bacteria
OU809_RS17895	COG0693	protein deglycase activity
OU809_RS17900	COG1349	DNA-binding transcription factor activity
OU809_RS17905	COG1070	Carbohydrate kinase
OU809_RS17910	COG4952	isomerase
OU809_RS17920	COG3347	Dehydrogenase
OU809_RS17920	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS17935	COG2814	Major facilitator Superfamily
OU809_RS17945	COG2124	cytochrome p450
OU809_RS17955	COG1846	Transcriptional regulator
OU809_RS17965	COG0673	inositol 2-dehydrogenase activity
OU809_RS17970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OU809_RS17975	COG1054	Belongs to the UPF0176 family
OU809_RS17985	COG1191	sigma factor activity
OU809_RS17995	COG2140	Oxalate decarboxylase
OU809_RS18015	COG5520	Belongs to the glycosyl hydrolase 30 family
OU809_RS18020	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS18065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OU809_RS18070	COG0557	exoribonuclease II activity
OU809_RS18075	COG1647	Serine aminopeptidase, S33
OU809_RS18080	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OU809_RS18085	COG2002	toxin-antitoxin pair type II binding
OU809_RS18090	COG1476	TRANSCRIPTIONal
OU809_RS18095	COG1396	sequence-specific DNA binding
OU809_RS18100	COG1396	sequence-specific DNA binding
OU809_RS18105	COG1174	glycine betaine transport
OU809_RS18110	COG1732	Glycine betaine
OU809_RS18115	COG1174	glycine betaine transport
OU809_RS18120	COG0517	IMP dehydrogenase activity
OU809_RS18120	COG1125	glycine betaine transport
OU809_RS18125	COG1510	regulation of RNA biosynthetic process
OU809_RS18130	COG2095	MarC family integral membrane protein
OU809_RS18135	COG3064	Membrane
OU809_RS18140	COG4640	response to antibiotic
OU809_RS18145	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS18160	COG0693	protein deglycase activity
OU809_RS18165	COG0148	phosphopyruvate hydratase activity
OU809_RS18170	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OU809_RS18175	COG0149	triose-phosphate isomerase activity
OU809_RS18180	COG0126	phosphoglycerate kinase activity
OU809_RS18185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OU809_RS18190	COG2390	Transcriptional regulator
OU809_RS18195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU809_RS18200	COG1113	amino acid transport
OU809_RS18220	COG1556	Lactate utilization protein
OU809_RS18225	COG1139	Iron-sulfur cluster binding protein
OU809_RS18230	COG0247	lactate metabolic process
OU809_RS18235	COG2186	Transcriptional regulator
OU809_RS18240	COG1620	l-lactate permease
OU809_RS18245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OU809_RS18255	COG5039	Polysaccharide pyruvyl transferase
OU809_RS18260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU809_RS18265	COG0110	maltose O-acetyltransferase activity
OU809_RS18270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OU809_RS18275	COG2244	polysaccharide biosynthetic process
OU809_RS18280	COG1216	Glycosyl transferase, family 2
OU809_RS18285	COG5039	Polysaccharide pyruvyl transferase
OU809_RS18290	COG1216	Glycosyl transferase, family 2
OU809_RS18300	COG0438	transferase activity, transferring glycosyl groups
OU809_RS18305	COG1215	transferase activity, transferring glycosyl groups
OU809_RS18310	COG0438	transferase activity, transferring glycosyl groups
OU809_RS18315	COG1086	Polysaccharide biosynthesis protein
OU809_RS18320	COG0489	protein tyrosine kinase activity
OU809_RS18325	COG3944	biosynthesis protein
OU809_RS18330	COG1396	sequence-specific DNA binding
OU809_RS18335	COG2249	NAD(P)H dehydrogenase (quinone) activity
OU809_RS18340	COG2271	Major facilitator Superfamily
OU809_RS18350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OU809_RS18360	COG1454	alcohol dehydrogenase
OU809_RS18365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OU809_RS18375	COG1733	regulation of RNA biosynthetic process
OU809_RS18380	COG1902	pentaerythritol trinitrate reductase activity
OU809_RS18385	COG1621	beta-fructofuranosidase activity
OU809_RS18390	COG1621	beta-fructofuranosidase activity
OU809_RS18410	COG0740	serine-type endopeptidase activity
OU809_RS18415	COG1611	Belongs to the LOG family
OU809_RS18420	COG1694	Mazg nucleotide pyrophosphohydrolase
OU809_RS18425	COG1078	dGTPase activity
OU809_RS18430	COG0659	secondary active sulfate transmembrane transporter activity
OU809_RS18435	COG0288	reversible hydration of carbon dioxide
OU809_RS18440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU809_RS18445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OU809_RS18450	COG0640	Transcriptional regulator
OU809_RS18460	COG2732	(Barnase) inhibitor
OU809_RS18465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OU809_RS18470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS18475	COG1481	regulation of sporulation
OU809_RS18480	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OU809_RS18485	COG1660	Displays ATPase and GTPase activities
OU809_RS18490	COG1051	belongs to the nudix hydrolase family
OU809_RS18495	COG0492	ferredoxin-NADP+ reductase activity
OU809_RS18500	COG0457	Tetratricopeptide repeat
OU809_RS18505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS18510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OU809_RS18510	COG0140	phosphoribosyl-ATP diphosphatase activity
OU809_RS18515	COG0107	imidazoleglycerol-phosphate synthase activity
OU809_RS18520	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OU809_RS18525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OU809_RS18530	COG0131	Imidazoleglycerol-phosphate dehydratase
OU809_RS18535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OU809_RS18540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OU809_RS18545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OU809_RS18550	COG4990	cell redox homeostasis
OU809_RS18555	COG5297	Belongs to the glycosyl hydrolase family 6
OU809_RS18560	COG0110	maltose O-acetyltransferase activity
OU809_RS18565	COG0546	phosphoglycolate phosphatase activity
OU809_RS18570	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OU809_RS18575	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OU809_RS18580	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OU809_RS18585	COG1846	Transcriptional regulator
OU809_RS18590	COG2814	Major facilitator Superfamily
OU809_RS18595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OU809_RS18600	COG1950	PFAM Membrane protein of
OU809_RS18605	COG1983	PspC domain protein
OU809_RS18610	COG3595	metallopeptidase activity
OU809_RS18630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OU809_RS18635	COG0556	nucleotide-excision repair
OU809_RS18640	COG4897	Protein conserved in bacteria
OU809_RS18650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU809_RS18660	COG0793	Belongs to the peptidase S41A family
OU809_RS18660	COG3409	Peptidoglycan-binding domain 1 protein
OU809_RS18665	COG0473	3-isopropylmalate dehydrogenase activity
OU809_RS18670	COG0791	NLP P60 protein
OU809_RS18670	COG3883	PFAM NLP P60 protein
OU809_RS18675	COG2177	Part of the ABC transporter FtsEX involved in
OU809_RS18680	COG2884	Cell division ATP-binding protein ftsE
OU809_RS18685	COG2010	Cytochrome c
OU809_RS18690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS18700	COG0653	protein targeting
OU809_RS18705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OU809_RS18720	COG1516	flagellar protein fliS
OU809_RS18725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OU809_RS18730	COG1334	flagellar protein FlaG
OU809_RS18740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OU809_RS18745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OU809_RS18750	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OU809_RS18760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OU809_RS18765	COG1256	bacterial-type flagellum assembly
OU809_RS18765	COG4786	Flagellar basal body rod
OU809_RS18770	COG3418	PFAM FlgN family protein
OU809_RS18775	COG2747	anti-sigma28 factor FlgM
OU809_RS18785	COG1040	competence protein
OU809_RS18795	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OU809_RS18800	COG1307	EDD domain protein, DegV family
OU809_RS18805	COG2197	response regulator
OU809_RS18810	COG4585	Histidine kinase
OU809_RS18815	COG1739	Uncharacterized protein family UPF0029
OU809_RS18820	COG1316	TRANSCRIPTIONal
OU809_RS18830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OU809_RS18835	COG0438	transferase activity, transferring glycosyl groups
OU809_RS18840	COG1215	transferase activity, transferring glycosyl groups
OU809_RS18845	COG3206	protein involved in exopolysaccharide biosynthesis
OU809_RS18850	COG3307	-O-antigen
OU809_RS18855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OU809_RS18860	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OU809_RS18865	COG0438	transferase activity, transferring glycosyl groups
OU809_RS18865	COG0297	glycogen (starch) synthase activity
OU809_RS18870	COG2244	polysaccharide biosynthetic process
OU809_RS18880	COG0860	N-Acetylmuramoyl-L-alanine amidase
OU809_RS18880	COG2247	cell wall binding repeat
OU809_RS18885	COG2247	cell wall binding repeat
OU809_RS18885	COG2385	sporulation resulting in formation of a cellular spore
OU809_RS18895	COG1316	TRANSCRIPTIONal
OU809_RS18900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OU809_RS18905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OU809_RS18915	COG1682	transport, permease protein
OU809_RS18920	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU809_RS18920	COG0463	Glycosyl transferase, family 2
OU809_RS18925	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU809_RS18930	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OU809_RS18935	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OU809_RS18940	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OU809_RS18945	COG4193	domain, Protein
OU809_RS18950	COG1482	cell wall glycoprotein biosynthetic process
OU809_RS18970	COG0800	Aldolase
OU809_RS18975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU809_RS18980	COG1609	Transcriptional regulator
OU809_RS18985	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OU809_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS18995	COG1063	alcohol dehydrogenase
OU809_RS19005	COG2814	Major facilitator Superfamily
OU809_RS19010	COG1316	TRANSCRIPTIONal
OU809_RS19015	COG0561	phosphatase activity
OU809_RS19020	COG0791	NLP P60 protein
OU809_RS19030	COG2843	Capsule synthesis protein
OU809_RS19040	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OU809_RS19045	COG1609	Transcriptional regulator
OU809_RS19050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU809_RS19055	COG1869	D-ribose catabolic process
OU809_RS19060	COG1129	ABC transporter
OU809_RS19065	COG1172	Belongs to the binding-protein-dependent transport system permease family
OU809_RS19070	COG1879	ABC-type sugar transport system periplasmic component
OU809_RS19075	COG0583	DNA-binding transcription factor activity
OU809_RS19080	COG2226	methyltransferase
OU809_RS19085	COG3527	Alpha-acetolactate decarboxylase
OU809_RS19090	COG0028	Belongs to the TPP enzyme family
OU809_RS19095	COG0583	DNA-binding transcription factor activity
OU809_RS19100	COG0405	Gamma-glutamyltransferase
OU809_RS19105	COG1522	sequence-specific DNA binding
OU809_RS19110	COG2059	Chromate
OU809_RS19115	COG2059	Chromate
OU809_RS19120	COG4464	protein tyrosine phosphatase activity
OU809_RS19125	COG3944	biosynthesis protein
OU809_RS19135	COG4715	Zinc finger, swim domain protein
OU809_RS19140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OU809_RS19145	COG3878	Protein conserved in bacteria
OU809_RS19150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OU809_RS19165	COG0561	phosphatase activity
OU809_RS19170	COG1349	DNA-binding transcription factor activity
OU809_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS19190	COG3732	PTS system glucitol sorbitol-specific
OU809_RS19210	COG0629	single-stranded DNA binding
OU809_RS19225	COG1970	mechanosensitive ion channel activity
OU809_RS19230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OU809_RS19235	COG4786	Flagellar basal body rod
OU809_RS19240	COG4786	Flagellar basal body rod
OU809_RS19245	COG1077	Cell shape determining protein MreB Mrl
OU809_RS19250	COG1609	Transcriptional regulator
OU809_RS19255	COG1846	Transcriptional regulator
OU809_RS19260	COG2814	Major facilitator Superfamily
OU809_RS19265	COG0671	phosphoesterase, PA-phosphatase related
OU809_RS19270	COG1227	inorganic diphosphatase activity
OU809_RS19275	COG3546	catalase activity
OU809_RS19280	COG3361	conserved protein (COG2071)
OU809_RS19295	COG0517	IMP dehydrogenase activity
OU809_RS19300	COG0598	Magnesium transport protein CorA
OU809_RS19305	COG1253	flavin adenine dinucleotide binding
OU809_RS19310	COG0004	ammonium transporteR
OU809_RS19315	COG0347	Belongs to the P(II) protein family
OU809_RS19320	COG0740	serine-type endopeptidase activity
OU809_RS19330	COG0739	heme binding
OU809_RS19335	COG1247	-acetyltransferase
OU809_RS19345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU809_RS19355	COG0477	Major facilitator Superfamily
OU809_RS19360	COG3251	PFAM MbtH domain protein
OU809_RS19365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS19370	COG3433	isochorismatase activity
OU809_RS19370	COG1535	isochorismatase
OU809_RS19375	COG1021	2,3-dihydroxybenzoate-AMP ligase
OU809_RS19380	COG1169	isochorismate synthase
OU809_RS19385	COG1028	Short-chain dehydrogenase reductase Sdr
OU809_RS19390	COG2819	hydrolase of the alpha beta superfamily
OU809_RS19395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS19400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS19405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS19410	COG2207	Transcriptional regulator
OU809_RS19410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS19425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OU809_RS19435	COG1959	2 iron, 2 sulfur cluster binding
OU809_RS19445	COG1994	Peptidase M50
OU809_RS19450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OU809_RS19455	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OU809_RS19460	COG2223	nitrite transmembrane transporter activity
OU809_RS19465	COG3383	formate dehydrogenase (NAD+) activity
OU809_RS19470	COG2304	oxidoreductase activity
OU809_RS19475	COG2304	oxidoreductase activity
OU809_RS19480	COG2385	sporulation resulting in formation of a cellular spore
OU809_RS19485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OU809_RS19495	COG4836	Membrane
OU809_RS19500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OU809_RS19505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OU809_RS19510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OU809_RS19515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OU809_RS19520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OU809_RS19525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OU809_RS19535	COG0356	it plays a direct role in the translocation of protons across the membrane
OU809_RS19545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OU809_RS19550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OU809_RS19555	COG4475	Protein of unknown function (DUF436)
OU809_RS19560	COG0698	ribose 5-phosphate isomerase
OU809_RS19565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OU809_RS19570	COG1971	Probably functions as a manganese efflux pump
OU809_RS19575	COG0009	L-threonylcarbamoyladenylate synthase
OU809_RS19580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OU809_RS19590	COG0738	Major facilitator superfamily
OU809_RS19595	COG0673	inositol 2-dehydrogenase activity
OU809_RS19600	COG0561	phosphatase activity
OU809_RS19605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OU809_RS19610	COG1609	Transcriptional regulator
OU809_RS19620	COG2890	protein-(glutamine-N5) methyltransferase activity
OU809_RS19625	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OU809_RS19630	COG0346	lactoylglutathione lyase activity
OU809_RS19635	COG0789	Transcriptional regulator
OU809_RS19640	COG0679	Auxin Efflux Carrier
OU809_RS19645	COG0281	malic enzyme
OU809_RS19650	COG1435	thymidine kinase activity
OU809_RS19655	COG0254	rRNA binding
OU809_RS19660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OU809_RS19665	COG1494	fructose-1,6-bisphosphatase
OU809_RS19670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OU809_RS19675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OU809_RS19680	COG0191	fructose-bisphosphate aldolase activity
OU809_RS19685	COG2204	response regulator
OU809_RS19690	COG4821	SIS domain
OU809_RS19695	COG0504	CTP synthase activity
OU809_RS19700	COG3343	RNA polymerase activity
OU809_RS19710	COG1960	acyl-CoA dehydrogenase activity
OU809_RS19715	COG1960	acyl-CoA dehydrogenase activity
OU809_RS19720	COG1250	3-hydroxyacyl-CoA dehydrogenase
OU809_RS19725	COG0183	Belongs to the thiolase family
OU809_RS19730	COG0247	lactate metabolic process
OU809_RS19730	COG2181	nitrate reductase activity
OU809_RS19735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OU809_RS19745	COG0018	arginyl-trna synthetase
OU809_RS19750	COG4506	Protein conserved in bacteria
OU809_RS19755	COG0010	Belongs to the arginase family
OU809_RS19760	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OU809_RS19765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OU809_RS19775	COG1994	Peptidase M50
OU809_RS19780	COG1942	4-Oxalocrotonate Tautomerase
OU809_RS19790	COG3465	dGTPase activity
OU809_RS19795	COG1078	dGTPase activity
OU809_RS19800	COG4844	belongs to the
OU809_RS19825	COG2814	Major facilitator Superfamily
OU809_RS19850	COG1414	Transcriptional regulator
OU809_RS19860	COG0280	phosphate acetyltransferase
OU809_RS19865	COG3253	May function as heme-dependent peroxidase
OU809_RS19875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OU809_RS19895	COG1131	(ABC) transporter
OU809_RS19910	COG2363	Small membrane protein
OU809_RS19915	COG2233	PERMEase
OU809_RS19925	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS19930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OU809_RS19935	COG1216	Glycosyl transferase, family 2
OU809_RS19940	COG0351	phosphomethylpyrimidine kinase
OU809_RS19950	COG1621	beta-fructofuranosidase activity
OU809_RS19955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS19955	COG1263	PTS System
OU809_RS19960	COG3711	transcriptional antiterminator
OU809_RS19970	COG1404	Belongs to the peptidase S8 family
OU809_RS19980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OU809_RS19990	COG0778	Nitroreductase
OU809_RS19995	COG1473	amidohydrolase
OU809_RS20000	COG0772	Belongs to the SEDS family
OU809_RS20005	COG0772	Belongs to the SEDS family
OU809_RS20010	COG3314	Sporulation integral membrane protein YlbJ
OU809_RS20025	COG0456	acetyltransferase
OU809_RS20060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OU809_RS20070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OU809_RS20075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OU809_RS20080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU809_RS20090	COG0655	NAD(P)H dehydrogenase (quinone) activity
OU809_RS20095	COG3162	membrane
OU809_RS20100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS20105	COG1070	Carbohydrate kinase
OU809_RS20110	COG2115	Belongs to the xylose isomerase family
OU809_RS20115	COG1940	carbohydrate kinase activity
OU809_RS20120	COG0352	thiamine-phosphate diphosphorylase activity
OU809_RS20125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OU809_RS20130	COG0583	DNA-binding transcription factor activity
OU809_RS20145	COG1380	Effector of murein hydrolase LrgA
OU809_RS20150	COG1346	cytolysis
OU809_RS20155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OU809_RS20160	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OU809_RS20170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OU809_RS20175	COG1442	glycosyl transferase family 8
OU809_RS20190	COG4585	Histidine kinase
OU809_RS20195	COG2197	response regulator
OU809_RS20200	COG2409	Drug exporters of the RND superfamily
OU809_RS20205	COG5522	Integral membrane protein (intg_mem_TP0381)
OU809_RS20210	COG2271	Major facilitator Superfamily
OU809_RS20215	COG4948	Mandelate Racemase Muconate Lactonizing
OU809_RS20220	COG0800	Aldolase
OU809_RS20225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU809_RS20235	COG2234	aminopeptidase activity
OU809_RS20245	COG0477	Major facilitator Superfamily
OU809_RS20260	COG2357	RelA SpoT domain protein
OU809_RS20275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OU809_RS20280	COG1696	Membrane protein involved in D-alanine export
OU809_RS20285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OU809_RS20290	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OU809_RS20295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OU809_RS20300	COG2814	Major facilitator Superfamily
OU809_RS20305	COG1486	melibiose metabolic process
OU809_RS20310	COG1447	Phosphotransferase system cellobiose-specific component IIA
OU809_RS20315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS20320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS20325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OU809_RS20325	COG3711	transcriptional antiterminator
OU809_RS20335	COG2094	Belongs to the DNA glycosylase MPG family
OU809_RS20345	COG0372	Belongs to the citrate synthase family
OU809_RS20350	COG2079	MmgE PrpD family protein
OU809_RS20355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OU809_RS20370	COG1132	(ABC) transporter
OU809_RS20375	COG2755	lipolytic protein G-D-S-L family
OU809_RS20390	COG2814	Major facilitator Superfamily
OU809_RS20395	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OU809_RS20400	COG1131	(ABC) transporter
OU809_RS20420	COG1595	DNA-templated transcription, initiation
OU809_RS20425	COG2814	Major facilitator Superfamily
OU809_RS20435	COG0753	catalase activity
OU809_RS20440	COG0753	catalase activity
OU809_RS20445	COG0735	belongs to the Fur family
OU809_RS20450	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OU809_RS20460	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OU809_RS20465	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OU809_RS20470	COG4988	ABC transporter
OU809_RS20475	COG1294	oxidase, subunit
OU809_RS20480	COG1271	oxidase subunit
OU809_RS20485	COG2116	formate transmembrane transporter activity
OU809_RS20495	COG0281	malic enzyme
OU809_RS20500	COG1757	Na H antiporter
OU809_RS20505	COG1027	Aspartate ammonia-lyase
OU809_RS20510	COG0252	asparaginase activity
OU809_RS20515	COG1396	sequence-specific DNA binding
OU809_RS20520	COG2706	6-phosphogluconolactonase activity
OU809_RS20525	COG0745	RESPONSE REGULATOR receiver
OU809_RS20530	COG2205	protein histidine kinase activity
OU809_RS20535	COG1136	(ABC) transporter
OU809_RS20540	COG0577	efflux transmembrane transporter activity
OU809_RS20545	COG5294	Protein conserved in bacteria
OU809_RS20560	COG0726	polysaccharide deacetylase
OU809_RS20565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OU809_RS20575	COG1215	transferase activity, transferring glycosyl groups
OU809_RS20580	COG3493	citrate carrier protein
OU809_RS20585	COG0584	glycerophosphoryl diester phosphodiesterase
OU809_RS20600	COG1368	sulfuric ester hydrolase activity
OU809_RS20610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OU809_RS20620	COG2235	arginine
OU809_RS20625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OU809_RS20635	COG0549	Belongs to the carbamate kinase family
OU809_RS20645	COG2723	6-phospho-beta-galactosidase activity
OU809_RS20650	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OU809_RS20660	COG1595	DNA-templated transcription, initiation
OU809_RS20670	COG2195	Cleaves the N-terminal amino acid of tripeptides
OU809_RS20680	COG2223	nitrite transmembrane transporter activity
OU809_RS20685	COG0395	ABC-type sugar transport system, permease component
OU809_RS20690	COG1175	transmembrane transport
OU809_RS20700	COG1609	Transcriptional regulator
OU809_RS20715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OU809_RS20720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OU809_RS20725	COG0463	Glycosyl transferase, family 2
OU809_RS20730	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU809_RS20755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU809_RS20765	COG0753	catalase activity
OU809_RS20765	COG0693	protein deglycase activity
OU809_RS20775	COG2723	6-phospho-beta-galactosidase activity
OU809_RS20780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS20780	COG1263	PTS System
OU809_RS20780	COG2190	(PTS) system
OU809_RS20785	COG3711	transcriptional antiterminator
OU809_RS20790	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OU809_RS20795	COG1122	ATPase activity
OU809_RS20800	COG4721	ABC-type cobalt transport system, permease component
OU809_RS20805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OU809_RS20815	COG2224	Isocitrate lyase
OU809_RS20820	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OU809_RS20830	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OU809_RS20875	COG0577	efflux transmembrane transporter activity
OU809_RS20880	COG1136	(ABC) transporter
OU809_RS20885	COG2205	protein histidine kinase activity
OU809_RS20890	COG0745	RESPONSE REGULATOR receiver
OU809_RS20895	COG2723	6-phospho-beta-galactosidase activity
OU809_RS20900	COG2190	(PTS) system
OU809_RS20900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS20900	COG1263	PTS System
OU809_RS20910	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OU809_RS20915	COG3507	Belongs to the glycosyl hydrolase 43 family
OU809_RS20920	COG0513	Belongs to the DEAD box helicase family
OU809_RS20935	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OU809_RS20940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OU809_RS20945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OU809_RS20950	COG2390	Transcriptional regulator
OU809_RS20955	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OU809_RS20960	COG3706	GGDEF domain
OU809_RS20965	COG5298	Protein conserved in bacteria
OU809_RS20970	COG1215	transferase activity, transferring glycosyl groups
OU809_RS20980	COG3977	Valine--pyruvate aminotransferase
OU809_RS20995	COG1181	Belongs to the D-alanine--D-alanine ligase family
OU809_RS21005	COG0191	fructose-bisphosphate aldolase activity
OU809_RS21010	COG1082	Xylose isomerase domain protein TIM barrel
OU809_RS21015	COG1082	Xylose isomerase domain protein TIM barrel
OU809_RS21020	COG0673	inositol 2-dehydrogenase activity
OU809_RS21025	COG2814	Major facilitator Superfamily
OU809_RS21030	COG1082	Xylose isomerase domain protein TIM barrel
OU809_RS21035	COG3962	Belongs to the TPP enzyme family
OU809_RS21040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OU809_RS21045	COG3718	enzyme involved in inositol metabolism
OU809_RS21050	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS21055	COG1349	DNA-binding transcription factor activity
OU809_RS21060	COG0667	Aldo Keto reductase
OU809_RS21065	COG0584	glycerophosphoryl diester phosphodiesterase
OU809_RS21070	COG2271	Major facilitator Superfamily
OU809_RS21075	COG0326	Molecular chaperone. Has ATPase activity
OU809_RS21080	COG0488	(ABC) transporter
OU809_RS21085	COG0561	phosphatase activity
OU809_RS21105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS21135	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OU809_RS21140	COG0577	efflux transmembrane transporter activity
OU809_RS21145	COG1136	(ABC) transporter
OU809_RS21150	COG2205	protein histidine kinase activity
OU809_RS21155	COG0745	RESPONSE REGULATOR receiver
OU809_RS21165	COG5278	phosphoserine phosphatase activity
OU809_RS21165	COG0840	transmembrane signaling receptor activity
OU809_RS21170	COG1115	amino acid carrier protein
OU809_RS21175	COG0686	Belongs to the AlaDH PNT family
OU809_RS21180	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OU809_RS21185	COG1874	Beta-galactosidase
OU809_RS21190	COG3833	ABC-type maltose transport systems, permease component
OU809_RS21195	COG1175	transmembrane transport
OU809_RS21200	COG2182	Extracellular solute-binding protein
OU809_RS21205	COG1609	Transcriptional regulator
OU809_RS21215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OU809_RS21220	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OU809_RS21225	COG1940	carbohydrate kinase activity
OU809_RS21235	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OU809_RS21265	COG1454	alcohol dehydrogenase
OU809_RS21265	COG1012	belongs to the aldehyde dehydrogenase family
OU809_RS21270	COG0450	alkyl hydroperoxide reductase
OU809_RS21275	COG3634	alkyl hydroperoxide reductase activity
OU809_RS21280	COG1113	amino acid transport
OU809_RS21285	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
OU809_RS21295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OU809_RS21300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OU809_RS21315	COG1131	(ABC) transporter
OU809_RS21320	COG0842	Transport permease protein
OU809_RS21325	COG4585	Histidine kinase
OU809_RS21330	COG2197	response regulator
OU809_RS21345	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OU809_RS21360	COG0456	acetyltransferase
OU809_RS21375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OU809_RS21380	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OU809_RS21385	COG4853	Protein conserved in bacteria
OU809_RS21390	COG4863	YycH protein
OU809_RS21395	COG5002	protein histidine kinase activity
OU809_RS21400	COG0745	RESPONSE REGULATOR receiver
OU809_RS21425	COG1051	belongs to the nudix hydrolase family
OU809_RS21430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OU809_RS21440	COG0305	Participates in initiation and elongation during chromosome replication
OU809_RS21455	COG3093	addiction module antidote protein HigA
OU809_RS21460	COG2807	transmembrane transport
OU809_RS21465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OU809_RS21470	COG0363	glucosamine-6-phosphate deaminase activity
OU809_RS21475	COG2188	Transcriptional regulator
OU809_RS21480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OU809_RS21485	COG1263	PTS System
OU809_RS21485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OU809_RS21490	COG0359	binds to the 23S rRNA
OU809_RS21495	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OU809_RS21500	COG4241	membrane
OU809_RS21510	COG5577	PFAM Coat F domain
OU809_RS21515	COG0589	response to stress
OU809_RS21520	COG0659	secondary active sulfate transmembrane transporter activity
OU809_RS21525	COG2271	Major facilitator Superfamily
OU809_RS21530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OU809_RS21535	COG0629	single-stranded DNA binding
OU809_RS21540	COG0360	Binds together with S18 to 16S ribosomal RNA
OU809_RS21545	COG0012	GTP binding
OU809_RS21550	COG4481	Protein conserved in bacteria
OU809_RS21555	COG3949	Membrane
OU809_RS21565	COG1475	DNA binding
OU809_RS21570	COG1192	Involved in chromosome partitioning
OU809_RS21575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OU809_RS21580	COG1595	DNA-templated transcription, initiation
OU809_RS21585	COG1475	DNA binding
OU809_RS21590	COG0357	Ribosomal RNA small subunit methyltransferase G
OU809_RS21595	COG0445	tRNA wobble uridine modification
OU809_RS21600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OU809_RS21605	COG1847	R3H domain protein
OU809_RS21610	COG0706	membrane insertase activity
OU809_RS21615	COG0594	ribonuclease P activity