locus-tag	class	description
SC10_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
SC10_RS00010	COG0592	DNA-directed DNA polymerase activity
SC10_RS00015	COG2501	S4 domain
SC10_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
SC10_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SC10_RS00070	COG0516	GMP reductase activity
SC10_RS00070	COG0517	IMP dehydrogenase activity
SC10_RS00075	COG1686	Belongs to the peptidase S11 family
SC10_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
SC10_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
SC10_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
SC10_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
SC10_RS00100	COG2610	gluconate transmembrane transporter activity
SC10_RS00105	COG3835	regulator
SC10_RS00120	COG1428	Deoxynucleoside kinase
SC10_RS00125	COG1428	Deoxynucleoside kinase
SC10_RS00130	COG3858	chitin binding
SC10_RS00130	COG1388	LysM domain
SC10_RS00135	COG1335	isochorismatase
SC10_RS00140	COG0590	tRNA wobble adenosine to inosine editing
SC10_RS00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SC10_RS00150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
SC10_RS00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
SC10_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
SC10_RS00200	COG3853	Toxic anion resistance protein (TelA)
SC10_RS00205	COG1982	Orn Lys Arg decarboxylase major
SC10_RS00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
SC10_RS00215	COG3870	Protein conserved in bacteria
SC10_RS00220	COG1728	Protein conserved in bacteria
SC10_RS00225	COG0470	DNA polymerase III
SC10_RS00230	COG1774	PSP1 C-terminal conserved region
SC10_RS00235	COG4467	Involved in initiation control of chromosome replication
SC10_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SC10_RS00245	COG2827	Endonuclease containing a URI domain
SC10_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
SC10_RS00255	COG2002	toxin-antitoxin pair type II binding
SC10_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SC10_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SC10_RS00265	COG0084	hydrolase, TatD family'
SC10_RS00270	COG3584	3D domain protein
SC10_RS00270	COG3583	domain protein
SC10_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SC10_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
SC10_RS00290	COG4466	Protein conserved in bacteria
SC10_RS00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
SC10_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SC10_RS00310	COG0251	oxidation-reduction process
SC10_RS00315	COG2088	sporulation resulting in formation of a cellular spore
SC10_RS00320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
SC10_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SC10_RS00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
SC10_RS00335	COG0193	aminoacyl-tRNA hydrolase activity
SC10_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SC10_RS00350	COG2002	toxin-antitoxin pair type II binding
SC10_RS00355	COG2244	polysaccharide biosynthetic process
SC10_RS00360	COG3956	TIGRFAM MazG family protein
SC10_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SC10_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
SC10_RS00385	COG1098	S1 RNA binding domain
SC10_RS00400	COG2208	phosphoserine phosphatase activity
SC10_RS00405	COG2304	oxidoreductase activity
SC10_RS00410	COG0515	serine threonine protein kinase
SC10_RS00415	COG0037	tRNA processing
SC10_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SC10_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SC10_RS00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
SC10_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
SC10_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SC10_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SC10_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SC10_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
SC10_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SC10_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SC10_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SC10_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SC10_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SC10_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SC10_RS00510	COG4463	regulation of RNA biosynthetic process
SC10_RS00515	COG3880	PFAM UvrB UvrC protein
SC10_RS00520	COG3869	Catalyzes the specific phosphorylation of arginine residues in
SC10_RS00525	COG0542	response to heat
SC10_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SC10_RS00535	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
SC10_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
SC10_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
SC10_RS00550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
SC10_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
SC10_RS00560	COG1045	serine acetyltransferase
SC10_RS00565	COG0215	cysteine-tRNA ligase activity
SC10_RS00570	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SC10_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SC10_RS00580	COG3688	RNA-binding protein containing a PIN domain
SC10_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
SC10_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
SC10_RS00605	COG0081	regulation of translation
SC10_RS00610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
SC10_RS00615	COG0222	ribosome binding
SC10_RS00620	COG2813	Specifically methylates the guanine in position
SC10_RS00625	COG0085	RNA polymerase activity
SC10_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
SC10_RS00635	COG1358	cellular component organization or biogenesis
SC10_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
SC10_RS00645	COG0049	tRNA binding
SC10_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
SC10_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
SC10_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
SC10_RS00670	COG0088	Forms part of the polypeptide exit tunnel
SC10_RS00675	COG0089	rRNA binding
SC10_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SC10_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
SC10_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
SC10_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
SC10_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
SC10_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SC10_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
SC10_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
SC10_RS00725	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
SC10_RS00730	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
SC10_RS00735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
SC10_RS00740	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
SC10_RS00745	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SC10_RS00750	COG1841	ribosomal large subunit assembly
SC10_RS00755	COG0200	Binds to the 23S rRNA
SC10_RS00760	COG0201	protein transport
SC10_RS00765	COG0563	adenylate kinase activity
SC10_RS00770	COG0024	Methionine aminopeptidase
SC10_RS00775	COG2163	COG2163 Ribosomal protein L14E L6E L27E
SC10_RS00780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SC10_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SC10_RS00790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
SC10_RS00795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SC10_RS00800	COG0202	RNA polymerase activity
SC10_RS00805	COG0203	ribosomal protein L17
SC10_RS00810	COG1122	ATPase activity
SC10_RS00815	COG1122	ATPase activity
SC10_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SC10_RS00825	COG0101	tRNA pseudouridine synthase activity
SC10_RS00830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SC10_RS00835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SC10_RS00855	COG2318	DinB family
SC10_RS00875	COG1131	(ABC) transporter
SC10_RS00905	COG2274	protein secretion by the type I secretion system
SC10_RS00930	COG3290	protein histidine kinase activity
SC10_RS00950	COG0860	N-Acetylmuramoyl-L-alanine amidase
SC10_RS00955	COG0489	protein tyrosine kinase activity
SC10_RS00965	COG2194	sulfuric ester hydrolase activity
SC10_RS00970	COG0726	polysaccharide deacetylase
SC10_RS01000	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SC10_RS01010	COG0385	Bile acid
SC10_RS01025	COG3876	Protein conserved in bacteria
SC10_RS01030	COG1472	Belongs to the glycosyl hydrolase 3 family
SC10_RS01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SC10_RS01040	COG1263	PTS System
SC10_RS01040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS01045	COG1737	Transcriptional regulator
SC10_RS01050	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SC10_RS01055	COG1683	Conserved Protein
SC10_RS01090	COG1595	DNA-templated transcription, initiation
SC10_RS01095	COG5662	AntiSigma factor
SC10_RS01100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SC10_RS01105	COG4856	YbbR-like protein
SC10_RS01110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SC10_RS01115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SC10_RS01135	COG1725	Transcriptional regulator
SC10_RS01145	COG0789	Transcriptional regulator
SC10_RS01155	COG0640	Transcriptional regulator
SC10_RS01160	COG2814	Major facilitator Superfamily
SC10_RS01170	COG1132	(ABC) transporter
SC10_RS01175	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SC10_RS01185	COG2312	Erythromycin esterase
SC10_RS01205	COG1011	Hydrolase
SC10_RS01225	COG2211	Major facilitator Superfamily
SC10_RS01245	COG1331	Highly conserved protein containing a thioredoxin domain
SC10_RS01265	COG1331	Highly conserved protein containing a thioredoxin domain
SC10_RS01275	COG3764	Sortase (surface protein transpeptidase)
SC10_RS01285	COG2002	toxin-antitoxin pair type II binding
SC10_RS01305	COG2226	methyltransferase
SC10_RS01310	COG0076	glutamate decarboxylase activity
SC10_RS01315	COG0778	Nitroreductase
SC10_RS01320	COG1802	Transcriptional regulator
SC10_RS01325	COG0730	response to heat
SC10_RS01345	COG1283	sodium-dependent phosphate transmembrane transporter activity
SC10_RS01350	COG4682	membrane
SC10_RS01360	COG3409	Peptidoglycan-binding domain 1 protein
SC10_RS01370	COG0697	spore germination
SC10_RS01375	COG1917	Cupin 2, conserved barrel domain protein
SC10_RS01375	COG2207	Transcriptional regulator
SC10_RS01385	COG2197	response regulator
SC10_RS01400	COG0371	Dehydrogenase
SC10_RS01415	COG4257	antibiotic catabolic process
SC10_RS01425	COG0833	amino acid
SC10_RS01430	COG2040	homocysteine
SC10_RS01440	COG1263	PTS System
SC10_RS01440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS01450	COG2323	membrane
SC10_RS01455	COG4451	ribulose bisphosphate carboxylase, small
SC10_RS01455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SC10_RS01460	COG2205	protein histidine kinase activity
SC10_RS01465	COG1115	amino acid carrier protein
SC10_RS01470	COG2066	Belongs to the glutaminase family
SC10_RS01475	COG4191	Histidine kinase
SC10_RS01480	COG0784	Response regulator, receiver
SC10_RS01505	COG3540	Alkaline phosphatase
SC10_RS01510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SC10_RS01515	COG0805	protein transport
SC10_RS01520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SC10_RS01525	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS01530	COG2271	Major facilitator Superfamily
SC10_RS01535	COG4948	Mandelate Racemase Muconate Lactonizing
SC10_RS01540	COG2186	Transcriptional regulator
SC10_RS01545	COG2721	sulfolactate sulfo-lyase activity
SC10_RS01565	COG0745	RESPONSE REGULATOR receiver
SC10_RS01570	COG2205	protein histidine kinase activity
SC10_RS01575	COG1131	(ABC) transporter
SC10_RS01600	COG3173	Aminoglycoside phosphotransferase
SC10_RS01605	COG1846	Transcriptional regulator
SC10_RS01610	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS01630	COG0789	Transcriptional regulator
SC10_RS01655	COG0697	spore germination
SC10_RS01665	COG3012	SEC-C Motif Domain Protein
SC10_RS01665	COG1405	negative regulation of cell septum assembly
SC10_RS01670	COG1131	(ABC) transporter
SC10_RS01695	COG0583	DNA-binding transcription factor activity
SC10_RS01700	COG1942	4-Oxalocrotonate Tautomerase
SC10_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS01720	COG1288	antiporter activity
SC10_RS01730	COG0252	asparaginase activity
SC10_RS01735	COG0456	acetyltransferase
SC10_RS01745	COG1164	Oligoendopeptidase f
SC10_RS01750	COG2261	transglycosylase associated protein
SC10_RS01760	COG0247	lactate metabolic process
SC10_RS01765	COG0277	FAD linked oxidase domain protein
SC10_RS01770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS01775	COG1447	Phosphotransferase system cellobiose-specific component IIA
SC10_RS01780	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS01785	COG1486	melibiose metabolic process
SC10_RS01790	COG2188	Transcriptional regulator
SC10_RS01795	COG3394	polysaccharide catabolic process
SC10_RS01810	COG3591	Belongs to the peptidase S1B family
SC10_RS01815	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS01825	COG1595	DNA-templated transcription, initiation
SC10_RS01835	COG3773	Cell wall hydrolase
SC10_RS01840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SC10_RS01845	COG3883	PFAM NLP P60 protein
SC10_RS01845	COG0791	NLP P60 protein
SC10_RS01855	COG1131	(ABC) transporter
SC10_RS01860	COG1309	transcriptional regulator
SC10_RS01880	COG2310	stress, protein
SC10_RS01885	COG2310	stress, protein
SC10_RS01890	COG2310	stress, protein
SC10_RS01895	COG0861	Integral membrane protein TerC family
SC10_RS01915	COG3853	Toxic anion resistance protein (TelA)
SC10_RS01920	COG0785	Cytochrome C biogenesis protein
SC10_RS01930	COG2223	nitrite transmembrane transporter activity
SC10_RS01935	COG0039	L-malate dehydrogenase activity
SC10_RS01940	COG1620	l-lactate permease
SC10_RS01945	COG1280	lysine exporter protein (LysE YggA)
SC10_RS01950	COG1113	amino acid transport
SC10_RS01955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
SC10_RS01960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SC10_RS01965	COG3541	Predicted nucleotidyltransferase
SC10_RS01975	COG0506	proline dehydrogenase activity
SC10_RS01980	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS01985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS01990	COG2508	Transcriptional regulator
SC10_RS01995	COG3689	TIGRFAM TIGR03943 family protein
SC10_RS02000	COG0701	Predicted permease
SC10_RS02005	COG3458	cephalosporin-C deacetylase activity
SC10_RS02025	COG0765	amino acid transport
SC10_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SC10_RS02035	COG2249	NAD(P)H dehydrogenase (quinone) activity
SC10_RS02040	COG1116	anion transmembrane transporter activity
SC10_RS02045	COG2723	6-phospho-beta-galactosidase activity
SC10_RS02055	COG3209	COG3209 Rhs family protein
SC10_RS02065	COG5444	nuclease activity
SC10_RS02095	COG1177	transmembrane transport
SC10_RS02100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS02105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS02110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS02115	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SC10_RS02120	COG0697	spore germination
SC10_RS02125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS02135	COG2819	hydrolase of the alpha beta superfamily
SC10_RS02140	COG2207	Transcriptional regulator
SC10_RS02140	COG3708	Transcriptional regulator
SC10_RS02145	COG2364	Membrane
SC10_RS02170	COG1126	abc transporter atp-binding protein
SC10_RS02175	COG0765	amino acid transport
SC10_RS02180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SC10_RS02185	COG3829	transcription factor binding
SC10_RS02190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SC10_RS02195	COG0833	amino acid
SC10_RS02200	COG0010	Belongs to the arginase family
SC10_RS02205	COG0583	DNA-binding transcription factor activity
SC10_RS02210	COG0163	prenyltransferase activity
SC10_RS02215	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
SC10_RS02285	COG5444	nuclease activity
SC10_RS02305	COG2972	Histidine kinase
SC10_RS02310	COG4753	response regulator
SC10_RS02310	COG2207	Transcriptional regulator
SC10_RS02315	COG4213	ABC transporter substrate-binding protein
SC10_RS02325	COG4214	carbohydrate transport
SC10_RS02330	COG2271	Major facilitator Superfamily
SC10_RS02335	COG1846	Transcriptional regulator
SC10_RS02335	COG0456	acetyltransferase
SC10_RS02340	COG1874	Beta-galactosidase
SC10_RS02345	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
SC10_RS02355	COG3104	oligopeptide transport
SC10_RS02360	COG5434	Belongs to the glycosyl hydrolase 28 family
SC10_RS02370	COG0697	spore germination
SC10_RS02380	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
SC10_RS02385	COG0789	Transcriptional regulator
SC10_RS02390	COG1136	(ABC) transporter
SC10_RS02395	COG0577	efflux transmembrane transporter activity
SC10_RS02400	COG0745	RESPONSE REGULATOR receiver
SC10_RS02405	COG3850	Histidine kinase
SC10_RS02405	COG5002	protein histidine kinase activity
SC10_RS02410	COG0840	transmembrane signaling receptor activity
SC10_RS02415	COG0527	aspartate kinase activity
SC10_RS02420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS02425	COG4605	iron ion homeostasis
SC10_RS02430	COG4604	ABC transporter, ATP-binding protein
SC10_RS02435	COG4607	ABC-type enterochelin transport system periplasmic component
SC10_RS02440	COG2814	Major facilitator Superfamily
SC10_RS02445	COG1309	transcriptional regulator
SC10_RS02455	COG0778	Nitroreductase
SC10_RS02460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SC10_RS02465	COG0640	Transcriptional regulator
SC10_RS02470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS02475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
SC10_RS02480	COG0531	amino acid
SC10_RS02485	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS02490	COG0697	spore germination
SC10_RS02500	COG4549	nuclear export factor GLE1
SC10_RS02505	COG2372	response to copper ion
SC10_RS02505	COG1276	copper resistance
SC10_RS02510	COG1349	DNA-binding transcription factor activity
SC10_RS02515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SC10_RS02520	COG0243	molybdopterin cofactor binding
SC10_RS02525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SC10_RS02530	COG2146	nitrite reductase [NAD(P)H] activity
SC10_RS02535	COG1587	Uroporphyrinogen-III synthase
SC10_RS02535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SC10_RS02540	COG1802	Transcriptional regulator
SC10_RS02545	COG0471	metal ion transport
SC10_RS02550	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SC10_RS02560	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS02575	COG3959	Transketolase, thiamine diphosphate binding domain
SC10_RS02580	COG3958	Transketolase
SC10_RS02585	COG0561	phosphatase activity
SC10_RS02590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
SC10_RS02595	COG1914	H( )-stimulated, divalent metal cation uptake system
SC10_RS02600	COG4336	lyase activity
SC10_RS02605	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
SC10_RS02610	COG1984	allophanate hydrolase subunit 2
SC10_RS02615	COG1414	Transcriptional regulator
SC10_RS02620	COG2755	lipolytic protein G-D-S-L family
SC10_RS02625	COG2213	PTS system mannitol-specific
SC10_RS02630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS02635	COG0246	Mannitol dehydrogenase
SC10_RS02640	COG3711	transcriptional antiterminator
SC10_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS02650	COG1917	Cupin 2, conserved barrel domain protein
SC10_RS02660	COG3871	stress protein (general stress protein 26)
SC10_RS02675	COG2814	Major facilitator Superfamily
SC10_RS02685	COG1522	sequence-specific DNA binding
SC10_RS02690	COG0551	DNA topoisomerase type I activity
SC10_RS02690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SC10_RS02695	COG0287	Prephenate dehydrogenase
SC10_RS02700	COG0512	Glutamine amidotransferase of anthranilate synthase
SC10_RS02700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SC10_RS02705	COG1605	Chorismate mutase
SC10_RS02710	COG0028	Belongs to the TPP enzyme family
SC10_RS02715	COG3397	chitin binding
SC10_RS02725	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SC10_RS02730	COG1914	H( )-stimulated, divalent metal cation uptake system
SC10_RS02735	COG2261	transglycosylase associated protein
SC10_RS02740	COG1027	Aspartate ammonia-lyase
SC10_RS02745	COG1819	glycosyl
SC10_RS02750	COG4876	unkown
SC10_RS02755	COG2217	Heavy metal translocating P-type atpase
SC10_RS02765	COG0662	Cupin 2, conserved barrel domain protein
SC10_RS02780	COG0628	permease
SC10_RS02785	COG1301	dicarboxylic acid transport
SC10_RS02790	COG1131	(ABC) transporter
SC10_RS02795	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SC10_RS02805	COG1960	acyl-CoA dehydrogenase activity
SC10_RS02820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS02825	COG1181	Belongs to the D-alanine--D-alanine ligase family
SC10_RS02830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SC10_RS02840	COG0513	Belongs to the DEAD box helicase family
SC10_RS02845	COG3402	PFAM membrane-flanked domain
SC10_RS02850	COG3428	Bacterial PH domain
SC10_RS02855	COG0705	Rhomboid family
SC10_RS02860	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
SC10_RS02865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SC10_RS02870	COG0864	Transcriptional regulator
SC10_RS02875	COG2337	Toxic component of a toxin-antitoxin (TA) module
SC10_RS02880	COG1366	Belongs to the anti-sigma-factor antagonist family
SC10_RS02885	COG1366	Belongs to the anti-sigma-factor antagonist family
SC10_RS02890	COG2172	sigma factor antagonist activity
SC10_RS02895	COG2208	phosphoserine phosphatase activity
SC10_RS02910	COG1191	sigma factor activity
SC10_RS02915	COG2208	phosphoserine phosphatase activity
SC10_RS02920	COG2183	response to ionizing radiation
SC10_RS02925	COG1309	transcriptional regulator
SC10_RS02935	COG2409	Drug exporters of the RND superfamily
SC10_RS02935	COG1033	growth of symbiont in host cell
SC10_RS02940	COG3091	SprT-like family
SC10_RS03005	COG0726	polysaccharide deacetylase
SC10_RS03010	COG3239	Fatty acid desaturase
SC10_RS03015	COG1278	Cold shock
SC10_RS03025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS03030	COG0477	Major facilitator Superfamily
SC10_RS03040	COG2364	Membrane
SC10_RS03045	COG1846	Transcriptional regulator
SC10_RS03050	COG0456	acetyltransferase
SC10_RS03055	COG2808	Putative FMN-binding domain
SC10_RS03065	COG1733	regulation of RNA biosynthetic process
SC10_RS03070	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS03085	COG3545	Serine hydrolase
SC10_RS03090	COG1733	regulation of RNA biosynthetic process
SC10_RS03105	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
SC10_RS03125	COG0596	Alpha beta hydrolase
SC10_RS03130	COG5566	PFAM Mor transcription activator
SC10_RS03135	COG1595	DNA-templated transcription, initiation
SC10_RS03145	COG2755	lipolytic protein G-D-S-L family
SC10_RS03145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
SC10_RS03150	COG0494	nUDIX hydrolase
SC10_RS03155	COG2814	Major facilitator Superfamily
SC10_RS03160	COG1979	alcohol dehydrogenase
SC10_RS03165	COG0745	RESPONSE REGULATOR receiver
SC10_RS03165	COG2972	Histidine kinase
SC10_RS03170	COG3279	Response regulator of the LytR AlgR family
SC10_RS03180	COG3764	Sortase (surface protein transpeptidase)
SC10_RS03190	COG2814	Major facilitator Superfamily
SC10_RS03230	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
SC10_RS03235	COG0802	atpase or kinase
SC10_RS03240	COG1214	PFAM Peptidase M22, glycoprotease
SC10_RS03245	COG0456	acetyltransferase
SC10_RS03250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
SC10_RS03255	COG0488	(ABC) transporter
SC10_RS03260	COG0315	cyclic pyranopterin monophosphate synthase activity
SC10_RS03265	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
SC10_RS03270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
SC10_RS03275	COG0805	protein transport
SC10_RS03285	COG1266	CAAX protease self-immunity
SC10_RS03290	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
SC10_RS03295	COG0459	protein refolding
SC10_RS03300	COG4974	Belongs to the 'phage' integrase family
SC10_RS03305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SC10_RS03400	COG0582	viral genome integration into host DNA
SC10_RS03415	COG1598	PFAM Uncharacterised protein family UPF0150
SC10_RS03500	COG3953	SLT domain
SC10_RS03500	COG5280	Phage tail tape measure protein TP901
SC10_RS03555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SC10_RS03575	COG2720	vancomycin resistance protein
SC10_RS03595	COG2135	peptidase activity
SC10_RS03605	COG1309	transcriptional regulator
SC10_RS03610	COG0574	Belongs to the PEP-utilizing enzyme family
SC10_RS03610	COG3848	Pyruvate phosphate dikinase
SC10_RS03625	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
SC10_RS03630	COG2272	Belongs to the type-B carboxylesterase lipase family
SC10_RS03635	COG2814	Major facilitator Superfamily
SC10_RS03640	COG1842	Phage shock protein A
SC10_RS03645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SC10_RS03650	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
SC10_RS03655	COG4260	virion core protein, lumpy skin disease virus
SC10_RS03665	COG1378	Sugar-specific transcriptional regulator TrmB
SC10_RS03670	COG1280	lysine exporter protein (LysE YggA)
SC10_RS03675	COG3339	Conserved Protein
SC10_RS03680	COG0772	Belongs to the SEDS family
SC10_RS03685	COG0772	Belongs to the SEDS family
SC10_RS03705	COG0726	polysaccharide deacetylase
SC10_RS03715	COG1609	Transcriptional regulator
SC10_RS03720	COG0366	Alpha amylase catalytic
SC10_RS03725	COG2182	Extracellular solute-binding protein
SC10_RS03730	COG1175	transmembrane transport
SC10_RS03735	COG3833	ABC-type maltose transport systems, permease component
SC10_RS03740	COG5521	maltodextrose utilization protein MalA
SC10_RS03745	COG1554	hydrolase, family 65, central catalytic
SC10_RS03750	COG0366	Alpha amylase catalytic
SC10_RS03755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SC10_RS03760	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SC10_RS03765	COG1846	Transcriptional regulator
SC10_RS03780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
SC10_RS03785	COG0823	Involved in the tonB-independent uptake of proteins
SC10_RS03810	COG0702	epimerase
SC10_RS03820	COG2132	Multicopper oxidase
SC10_RS03835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SC10_RS03840	COG0714	Associated with various cellular activities
SC10_RS03845	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
SC10_RS03850	COG1305	Transglutaminase-like
SC10_RS03855	COG0519	Catalyzes the synthesis of GMP from XMP
SC10_RS03855	COG0518	GMP synthase (glutamine-hydrolyzing) activity
SC10_RS03865	COG2252	PERMEase
SC10_RS03880	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
SC10_RS03890	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SC10_RS03895	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
SC10_RS03900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SC10_RS03905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
SC10_RS03910	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SC10_RS03915	COG0047	phosphoribosylformylglycinamidine synthase activity
SC10_RS03920	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SC10_RS03925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SC10_RS03930	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
SC10_RS03935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SC10_RS03940	COG0138	bifunctional purine biosynthesis protein purh
SC10_RS03945	COG0151	Belongs to the GarS family
SC10_RS03955	COG2124	cytochrome p450
SC10_RS03975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SC10_RS03980	COG1470	cell adhesion involved in biofilm formation
SC10_RS03985	COG4496	protein, YerC YecD
SC10_RS03990	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
SC10_RS03995	COG0210	DNA helicase
SC10_RS04000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
SC10_RS04005	COG4851	CamS sex pheromone cAM373 precursor
SC10_RS04010	COG2188	Transcriptional regulator
SC10_RS04030	COG1735	metal-dependent hydrolase with the TIM-barrel fold
SC10_RS04035	COG0626	cystathionine gamma-synthase activity
SC10_RS04040	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SC10_RS04045	COG3457	Alanine racemase
SC10_RS04050	COG0363	glucosamine-6-phosphate deaminase activity
SC10_RS04055	COG1285	pathogenesis
SC10_RS04060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS04065	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SC10_RS04070	COG0154	amidase activity
SC10_RS04075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
SC10_RS04090	COG4124	Belongs to the glycosyl hydrolase 26 family
SC10_RS04095	COG1309	transcriptional regulator
SC10_RS04100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
SC10_RS04110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SC10_RS04115	COG1957	nucleoside hydrolase
SC10_RS04120	COG1597	lipid kinase activity
SC10_RS04125	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SC10_RS04135	COG0653	protein targeting
SC10_RS04145	COG2190	(PTS) system
SC10_RS04145	COG1263	PTS System
SC10_RS04145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS04150	COG2723	6-phospho-beta-galactosidase activity
SC10_RS04155	COG3711	transcriptional antiterminator
SC10_RS04160	COG0457	Tetratricopeptide repeat
SC10_RS04175	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
SC10_RS04175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SC10_RS04180	COG3586	endonuclease activity
SC10_RS04185	COG0697	spore germination
SC10_RS04190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS04195	COG0697	spore germination
SC10_RS04200	COG0217	transcriptional regulatory protein
SC10_RS04215	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS04220	COG0840	transmembrane signaling receptor activity
SC10_RS04225	COG0109	protoheme IX farnesyltransferase activity
SC10_RS04230	COG1309	transcriptional regulator
SC10_RS04235	COG0471	metal ion transport
SC10_RS04240	COG0488	(ABC) transporter
SC10_RS04245	COG0583	DNA-binding transcription factor activity
SC10_RS04255	COG1469	GTP cyclohydrolase I activity
SC10_RS04270	COG0523	cobalamin synthesis protein
SC10_RS04275	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
SC10_RS04280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SC10_RS04285	COG0156	8-amino-7-oxononanoate synthase activity
SC10_RS04290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
SC10_RS04295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
SC10_RS04300	COG2124	cytochrome p450
SC10_RS04310	COG0789	Transcriptional regulator
SC10_RS04315	COG2814	Major facilitator Superfamily
SC10_RS04325	COG0488	(ABC) transporter
SC10_RS04330	COG0513	Belongs to the DEAD box helicase family
SC10_RS04335	COG2130	NADP-dependent
SC10_RS04350	COG0471	metal ion transport
SC10_RS04360	COG1136	(ABC) transporter
SC10_RS04380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS04390	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
SC10_RS04395	COG3858	chitin binding
SC10_RS04400	COG5658	integral membrane protein
SC10_RS04405	COG0640	Transcriptional regulator
SC10_RS04410	COG1254	Belongs to the acylphosphatase family
SC10_RS04415	COG2258	MOSC domain
SC10_RS04420	COG0024	Methionine aminopeptidase
SC10_RS04425	COG1368	sulfuric ester hydrolase activity
SC10_RS04435	COG1115	amino acid carrier protein
SC10_RS04440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS04440	COG1263	PTS System
SC10_RS04450	COG2188	Transcriptional regulator
SC10_RS04485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SC10_RS04490	COG1045	serine acetyltransferase
SC10_RS04495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SC10_RS04505	COG1215	transferase activity, transferring glycosyl groups
SC10_RS04510	COG0457	Tetratricopeptide repeat
SC10_RS04510	COG0463	Glycosyl transferase, family 2
SC10_RS04520	COG0673	inositol 2-dehydrogenase activity
SC10_RS04535	COG1733	regulation of RNA biosynthetic process
SC10_RS04540	COG0778	Nitroreductase
SC10_RS04545	COG0737	Belongs to the 5'-nucleotidase family
SC10_RS04550	COG0693	protein deglycase activity
SC10_RS04555	COG4840	Belongs to the UPF0435 family
SC10_RS04560	COG1115	amino acid carrier protein
SC10_RS04565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SC10_RS04570	COG4980	gas vesicle protein
SC10_RS04575	COG1295	ribonuclease BN
SC10_RS04580	COG0477	Major facilitator Superfamily
SC10_RS04590	COG0387	Pfam Sodium calcium exchanger
SC10_RS04600	COG0535	radical SAM domain protein
SC10_RS04610	COG0726	polysaccharide deacetylase
SC10_RS04615	COG0371	Dehydrogenase
SC10_RS04625	COG0598	Magnesium transport protein CorA
SC10_RS04630	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
SC10_RS04635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SC10_RS04640	COG4637	Psort location Cytoplasmic, score
SC10_RS04665	COG1819	glycosyl
SC10_RS04675	COG0477	Major facilitator Superfamily
SC10_RS04685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS04685	COG1263	PTS System
SC10_RS04690	COG3711	transcriptional antiterminator
SC10_RS04695	COG0288	reversible hydration of carbon dioxide
SC10_RS04700	COG3002	Belongs to the UPF0753 family
SC10_RS04705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SC10_RS04710	COG5609	conserved protein (DUF2294)
SC10_RS04720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SC10_RS04725	COG0022	dehydrogenase e1 component
SC10_RS04730	COG0508	dehydrogenase complex catalyzes the overall conversion of
SC10_RS04735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SC10_RS04740	COG3284	Transcriptional regulator
SC10_RS04745	COG1742	UPF0060 membrane protein
SC10_RS04750	COG1486	melibiose metabolic process
SC10_RS04755	COG1737	Transcriptional regulator
SC10_RS04760	COG1263	PTS System
SC10_RS04760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS04775	COG1733	regulation of RNA biosynthetic process
SC10_RS04780	COG2259	Doxx family
SC10_RS04785	COG2514	catechol 2,3-dioxygenase activity
SC10_RS04795	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS04800	COG1917	Cupin 2, conserved barrel domain protein
SC10_RS04800	COG2207	Transcriptional regulator
SC10_RS04805	COG1653	transport
SC10_RS04810	COG2249	NAD(P)H dehydrogenase (quinone) activity
SC10_RS04815	COG1051	belongs to the nudix hydrolase family
SC10_RS04825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
SC10_RS04825	COG0392	lysyltransferase activity
SC10_RS04830	COG0384	phenazine biosynthesis protein PhzF
SC10_RS04835	COG0778	Nitroreductase
SC10_RS04850	COG1090	epimerase
SC10_RS04855	COG2137	regulation of response to DNA damage stimulus
SC10_RS04875	COG0463	Glycosyl transferase, family 2
SC10_RS04885	COG4485	Bacterial membrane protein, YfhO
SC10_RS04890	COG1988	membrane-bound metal-dependent
SC10_RS04895	COG1194	a g-specific adenine glycosylase
SC10_RS04905	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS04920	COG3557	Belongs to the UPF0374 family
SC10_RS04925	COG1132	(ABC) transporter
SC10_RS04930	COG0444	Belongs to the ABC transporter superfamily
SC10_RS04935	COG4608	Belongs to the ABC transporter superfamily
SC10_RS04940	COG0747	negative chemotaxis
SC10_RS04945	COG0601	transmembrane transport
SC10_RS04950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS04955	COG4129	membrane
SC10_RS04960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SC10_RS04965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
SC10_RS04970	COG0735	belongs to the Fur family
SC10_RS05185	COG0582	viral genome integration into host DNA
SC10_RS05215	COG4626	Terminase
SC10_RS05215	COG1802	Transcriptional regulator
SC10_RS05275	COG5280	Phage tail tape measure protein TP901
SC10_RS05275	COG3953	SLT domain
SC10_RS05285	COG1705	Flagellar rod assembly protein muramidase FlgJ
SC10_RS05335	COG5444	nuclease activity
SC10_RS05365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SC10_RS05385	COG0710	3-dehydroquinate dehydratase activity
SC10_RS05390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
SC10_RS05395	COG1116	anion transmembrane transporter activity
SC10_RS05400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SC10_RS05405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SC10_RS05410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SC10_RS05420	COG1476	TRANSCRIPTIONal
SC10_RS05430	COG1131	(ABC) transporter
SC10_RS05450	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SC10_RS05460	COG3382	B3 4 domain protein
SC10_RS05465	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
SC10_RS05475	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
SC10_RS05480	COG0789	Transcriptional regulator
SC10_RS05485	COG1664	Polymer-forming cytoskeletal
SC10_RS05490	COG1664	Polymer-forming cytoskeletal
SC10_RS05500	COG2766	serine protein kinase
SC10_RS05505	COG2718	Belongs to the UPF0229 family
SC10_RS05510	COG1566	PFAM secretion protein HlyD family protein
SC10_RS05515	COG2814	Major facilitator Superfamily
SC10_RS05520	COG0655	NAD(P)H dehydrogenase (quinone) activity
SC10_RS05530	COG1131	(ABC) transporter
SC10_RS05535	COG1131	(ABC) transporter
SC10_RS05540	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SC10_RS05545	COG1278	Cold shock
SC10_RS05550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SC10_RS05555	COG2011	ABC-type metal ion transport system permease component
SC10_RS05560	COG1464	Belongs to the NlpA lipoprotein family
SC10_RS05565	COG1823	symporter activity
SC10_RS05590	COG5577	PFAM Coat F domain
SC10_RS05605	COG5002	protein histidine kinase activity
SC10_RS05610	COG1525	nuclease
SC10_RS05610	COG4085	toxin activity
SC10_RS05610	COG0737	Belongs to the 5'-nucleotidase family
SC10_RS05615	COG3764	Sortase (surface protein transpeptidase)
SC10_RS05620	COG0564	pseudouridine synthase activity
SC10_RS05630	COG0517	IMP dehydrogenase activity
SC10_RS05635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
SC10_RS05640	COG3153	acetyltransferase
SC10_RS05640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SC10_RS05645	COG0488	(ABC) transporter
SC10_RS05650	COG2116	formate transmembrane transporter activity
SC10_RS05665	COG0604	alcohol dehydrogenase
SC10_RS05670	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
SC10_RS05675	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SC10_RS05680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
SC10_RS05685	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SC10_RS05690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SC10_RS05705	COG4585	Histidine kinase
SC10_RS05705	COG2203	Gaf domain
SC10_RS05710	COG2197	response regulator
SC10_RS05715	COG0431	NADPH-dependent FMN reductase
SC10_RS05730	COG1959	2 iron, 2 sulfur cluster binding
SC10_RS05735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SC10_RS05735	COG1017	nitric oxide dioxygenase activity
SC10_RS05740	COG2719	SpoVR family
SC10_RS05745	COG1388	LysM domain
SC10_RS05745	COG0791	NLP P60 protein
SC10_RS05750	COG0583	DNA-binding transcription factor activity
SC10_RS05755	COG0372	Belongs to the citrate synthase family
SC10_RS05760	COG2133	pyrroloquinoline quinone binding
SC10_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS05770	COG0733	neurotransmitter:sodium symporter activity
SC10_RS05785	COG5444	nuclease activity
SC10_RS05790	COG3708	Transcriptional regulator
SC10_RS05790	COG2207	Transcriptional regulator
SC10_RS05795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS05815	COG1595	DNA-templated transcription, initiation
SC10_RS05820	COG0662	Cupin 2, conserved barrel domain protein
SC10_RS05825	COG0667	Aldo Keto reductase
SC10_RS05830	COG0204	Acyl-transferase
SC10_RS05835	COG3152	Membrane
SC10_RS05850	COG1253	flavin adenine dinucleotide binding
SC10_RS05855	COG0789	Transcriptional regulator
SC10_RS05860	COG1253	flavin adenine dinucleotide binding
SC10_RS05880	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SC10_RS05885	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SC10_RS05890	COG0584	glycerophosphoryl diester phosphodiesterase
SC10_RS05895	COG0668	transmembrane transport
SC10_RS05900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
SC10_RS05910	COG0726	polysaccharide deacetylase
SC10_RS05920	COG1757	Na H antiporter
SC10_RS05925	COG2017	converts alpha-aldose to the beta-anomer
SC10_RS05950	COG0589	response to stress
SC10_RS05955	COG1132	(ABC) transporter
SC10_RS05960	COG1132	(ABC) transporter
SC10_RS05965	COG0702	epimerase
SC10_RS05980	COG3842	ATPase activity
SC10_RS05985	COG2508	Transcriptional regulator
SC10_RS05995	COG0189	ligase activity
SC10_RS06000	COG0189	ligase activity
SC10_RS06005	COG4399	Belongs to the UPF0754 family
SC10_RS06010	COG3679	Belongs to the UPF0342 family
SC10_RS06015	COG0561	phosphatase activity
SC10_RS06020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SC10_RS06025	COG0475	glutathione-regulated potassium exporter activity
SC10_RS06030	COG0490	domain, Protein
SC10_RS06040	COG1024	Enoyl-CoA hydratase
SC10_RS06045	COG0457	Tetratricopeptide repeat
SC10_RS06060	COG4152	abc transporter atp-binding protein
SC10_RS06065	COG1668	transmembrane transport
SC10_RS06070	COG0420	3'-5' exonuclease activity
SC10_RS06075	COG4717	serine-type aminopeptidase activity
SC10_RS06080	COG3481	metal-dependent phosphohydrolase, HD sub domain
SC10_RS06090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
SC10_RS06115	COG1846	Transcriptional regulator
SC10_RS06120	COG4980	gas vesicle protein
SC10_RS06135	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
SC10_RS06140	COG0537	adenosine 5'-monophosphoramidase activity
SC10_RS06145	COG1131	(ABC) transporter
SC10_RS06150	COG4473	ABC transporter
SC10_RS06160	COG1473	amidohydrolase
SC10_RS06165	COG3069	C4-dicarboxylate transmembrane transporter activity
SC10_RS06170	COG2329	Antibiotic biosynthesis monooxygenase
SC10_RS06175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SC10_RS06180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
SC10_RS06185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SC10_RS06190	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
SC10_RS06195	COG1309	transcriptional regulator
SC10_RS06200	COG1511	domain protein
SC10_RS06205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SC10_RS06210	COG1363	Peptidase, m42
SC10_RS06220	COG1301	dicarboxylic acid transport
SC10_RS06225	COG1234	tRNA 3'-trailer cleavage
SC10_RS06230	COG0095	Lipoate-protein ligase
SC10_RS06235	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS06245	COG1396	sequence-specific DNA binding
SC10_RS06260	COG0501	Belongs to the peptidase M48B family
SC10_RS06270	COG0697	spore germination
SC10_RS06275	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
SC10_RS06280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS06285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS06290	COG0406	alpha-ribazole phosphatase activity
SC10_RS06295	COG0840	transmembrane signaling receptor activity
SC10_RS06300	COG0723	plastoquinol--plastocyanin reductase activity
SC10_RS06300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SC10_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS06315	COG4903	ComK protein
SC10_RS06325	COG0398	Pfam SNARE associated Golgi protein
SC10_RS06330	COG0681	Belongs to the peptidase S26 family
SC10_RS06340	COG1404	Belongs to the peptidase S8 family
SC10_RS06350	COG2508	Transcriptional regulator
SC10_RS06355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SC10_RS06360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SC10_RS06365	COG3257	ureidoglycine aminohydrolase activity
SC10_RS06370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SC10_RS06375	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
SC10_RS06380	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SC10_RS06385	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SC10_RS06395	COG0549	Belongs to the carbamate kinase family
SC10_RS06410	COG0457	Tetratricopeptide repeat
SC10_RS06420	COG1609	Transcriptional regulator
SC10_RS06425	COG1653	transport
SC10_RS06430	COG1175	transmembrane transport
SC10_RS06435	COG0395	ABC-type sugar transport system, permease component
SC10_RS06440	COG1486	melibiose metabolic process
SC10_RS06445	COG3180	Ammonia monooxygenase
SC10_RS06460	COG3546	catalase activity
SC10_RS06465	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS06475	COG4533	DNA binding
SC10_RS06485	COG5002	protein histidine kinase activity
SC10_RS06490	COG0745	RESPONSE REGULATOR receiver
SC10_RS06495	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SC10_RS06500	COG0725	ABC transporter, periplasmic molybdate-binding protein
SC10_RS06505	COG4149	molybdate abc transporter
SC10_RS06510	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
SC10_RS06515	COG1074	ATP-dependent DNA helicase activity
SC10_RS06520	COG0420	3'-5' exonuclease activity
SC10_RS06525	COG0419	ATPase involved in DNA repair
SC10_RS06570	COG5337	Spore coat protein CotH
SC10_RS06580	COG0179	Fumarylacetoacetate (FAA) hydrolase
SC10_RS06600	COG0367	asparagine synthase
SC10_RS06605	COG0004	ammonium transporteR
SC10_RS06610	COG0347	Belongs to the P(II) protein family
SC10_RS06615	COG0534	Mate efflux family protein
SC10_RS06620	COG1917	Cupin 2, conserved barrel domain protein
SC10_RS06620	COG2207	Transcriptional regulator
SC10_RS06630	COG1609	Transcriptional regulator
SC10_RS06635	COG0673	inositol 2-dehydrogenase activity
SC10_RS06650	COG0697	spore germination
SC10_RS06655	COG1279	arginine transmembrane transporter activity
SC10_RS06660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS06670	COG0076	glutamate decarboxylase activity
SC10_RS06695	COG2153	protein acetylation
SC10_RS06700	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS06705	COG2378	regulation of single-species biofilm formation
SC10_RS06710	COG0646	methionine synthase
SC10_RS06710	COG1410	methionine synthase
SC10_RS06715	COG0646	methionine synthase
SC10_RS06715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SC10_RS06720	COG1666	GTP binding
SC10_RS06725	COG2996	Protein conserved in bacteria
SC10_RS06735	COG1307	EDD domain protein, DegV family
SC10_RS06740	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS06750	COG0516	GMP reductase activity
SC10_RS06760	COG0561	phosphatase activity
SC10_RS06765	COG1073	alpha beta
SC10_RS06770	COG2151	metal-sulfur cluster biosynthetic enzyme
SC10_RS06780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
SC10_RS06785	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
SC10_RS06790	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
SC10_RS06795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
SC10_RS06800	COG0505	Belongs to the CarA family
SC10_RS06805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SC10_RS06810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SC10_RS06815	COG1968	undecaprenyl-diphosphatase activity
SC10_RS06830	COG2267	carboxylic ester hydrolase activity
SC10_RS06840	COG1744	ABC transporter substrate-binding protein PnrA-like
SC10_RS06855	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SC10_RS06860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SC10_RS06870	COG5504	Zn-dependent protease
SC10_RS06875	COG0444	Belongs to the ABC transporter superfamily
SC10_RS06880	COG4608	Belongs to the ABC transporter superfamily
SC10_RS06890	COG0601	transmembrane transport
SC10_RS06895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS06910	COG0180	Tryptophanyl-tRNA synthetase
SC10_RS06920	COG4166	transmembrane transport
SC10_RS06925	COG0601	transmembrane transport
SC10_RS06930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS06935	COG0444	Belongs to the ABC transporter superfamily
SC10_RS06940	COG4608	Belongs to the ABC transporter superfamily
SC10_RS06945	COG0456	acetyltransferase
SC10_RS06950	COG1393	Belongs to the ArsC family
SC10_RS06955	COG0861	Integral membrane protein TerC family
SC10_RS06960	COG4862	establishment of competence for transformation
SC10_RS06985	COG4565	transcriptional regulatory protein
SC10_RS06990	COG3290	protein histidine kinase activity
SC10_RS06995	COG4469	Competence protein
SC10_RS07000	COG1164	Oligoendopeptidase f
SC10_RS07010	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
SC10_RS07015	COG2346	COG2346, Truncated hemoglobins
SC10_RS07025	COG0741	lytic transglycosylase activity
SC10_RS07030	COG4116	CYTH
SC10_RS07040	COG2357	RelA SpoT domain protein
SC10_RS07045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SC10_RS07050	COG0564	pseudouridine synthase activity
SC10_RS07055	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SC10_RS07060	COG0569	domain protein
SC10_RS07060	COG0475	glutathione-regulated potassium exporter activity
SC10_RS07065	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SC10_RS07070	COG0352	thiamine-phosphate diphosphorylase activity
SC10_RS07080	COG2104	thiamine diphosphate biosynthetic process
SC10_RS07085	COG2022	thiamine diphosphate biosynthetic process
SC10_RS07090	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SC10_RS07095	COG0351	phosphomethylpyrimidine kinase
SC10_RS07100	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
SC10_RS07155	COG0210	DNA helicase
SC10_RS07165	COG0586	Pfam SNARE associated Golgi protein
SC10_RS07170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SC10_RS07175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SC10_RS07180	COG2246	polysaccharide biosynthetic process
SC10_RS07185	COG2153	protein acetylation
SC10_RS07190	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SC10_RS07195	COG2382	esterase
SC10_RS07215	COG0626	cystathionine gamma-synthase activity
SC10_RS07220	COG0626	cystathionine gamma-synthase activity
SC10_RS07225	COG5505	Protein of unknown function (DUF819)
SC10_RS07240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SC10_RS07250	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS07305	COG0110	maltose O-acetyltransferase activity
SC10_RS07315	COG0583	DNA-binding transcription factor activity
SC10_RS07320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SC10_RS07325	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
SC10_RS07330	COG0583	DNA-binding transcription factor activity
SC10_RS07335	COG0697	spore germination
SC10_RS07340	COG0346	lactoylglutathione lyase activity
SC10_RS07350	COG1388	LysM domain
SC10_RS07350	COG3584	3D domain protein
SC10_RS07355	COG2814	Major facilitator Superfamily
SC10_RS07360	COG1309	transcriptional regulator
SC10_RS07375	COG4195	phage-related replication protein
SC10_RS07380	COG2856	Zn peptidase
SC10_RS07385	COG1396	sequence-specific DNA binding
SC10_RS07400	COG1522	sequence-specific DNA binding
SC10_RS07405	COG1484	DNA-dependent DNA replication
SC10_RS07420	COG1595	DNA-templated transcription, initiation
SC10_RS07425	COG3728	DNA packaging
SC10_RS07425	COG5484	DNA packaging
SC10_RS07430	COG1783	phage Terminase large subunit
SC10_RS07435	COG5518	Phage portal protein
SC10_RS07440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
SC10_RS07445	COG4653	Phage capsid family
SC10_RS07490	COG5412	phage tail tape measure protein
SC10_RS07490	COG3953	SLT domain
SC10_RS07495	COG1652	LysM domain
SC10_RS07500	COG4193	domain, Protein
SC10_RS07510	COG3628	GPW Gp25 family protein
SC10_RS07515	COG3299	homolog of phage Mu protein gp47
SC10_RS07520	COG3778	Protein conserved in bacteria
SC10_RS07550	COG1802	Transcriptional regulator
SC10_RS07555	COG1063	alcohol dehydrogenase
SC10_RS07560	COG1312	Catalyzes the dehydration of D-mannonate
SC10_RS07565	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS07570	COG1063	alcohol dehydrogenase
SC10_RS07575	COG2271	Major facilitator Superfamily
SC10_RS07590	COG0306	phosphate transporter
SC10_RS07595	COG1392	Phosphate transport regulator
SC10_RS07600	COG0405	Gamma-glutamyltransferase
SC10_RS07605	COG5578	integral membrane protein
SC10_RS07610	COG2972	Histidine kinase
SC10_RS07615	COG4753	response regulator
SC10_RS07615	COG2207	Transcriptional regulator
SC10_RS07620	COG1653	transport
SC10_RS07625	COG1175	transmembrane transport
SC10_RS07630	COG0395	ABC-type sugar transport system, permease component
SC10_RS07635	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SC10_RS07640	COG2207	Transcriptional regulator
SC10_RS07645	COG2755	lipolytic protein G-D-S-L family
SC10_RS07655	COG5578	integral membrane protein
SC10_RS07660	COG3401	FG-GAP repeat protein
SC10_RS07675	COG3401	FG-GAP repeat protein
SC10_RS07680	COG0667	Aldo Keto reductase
SC10_RS07685	COG2755	lipolytic protein G-D-S-L family
SC10_RS07690	COG1874	Beta-galactosidase
SC10_RS07700	COG1653	transport
SC10_RS07705	COG4209	transmembrane transport
SC10_RS07710	COG0395	ABC-type sugar transport system, permease component
SC10_RS07715	COG0531	amino acid
SC10_RS07720	COG0346	lactoylglutathione lyase activity
SC10_RS07725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SC10_RS07730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SC10_RS07735	COG2362	D-Aminopeptidase
SC10_RS07740	COG0601	transmembrane transport
SC10_RS07745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS07750	COG0444	Belongs to the ABC transporter superfamily
SC10_RS07755	COG4166	transmembrane transport
SC10_RS07760	COG1619	proteins homologs of microcin C7 resistance protein MccF
SC10_RS07765	COG4948	Mandelate Racemase Muconate Lactonizing
SC10_RS07770	COG0791	NLP P60 protein
SC10_RS07775	COG4608	Belongs to the ABC transporter superfamily
SC10_RS07780	COG1834	amidinotransferase
SC10_RS07785	COG1607	acyl-coa hydrolase
SC10_RS07790	COG2323	membrane
SC10_RS07795	COG3866	Pectate lyase
SC10_RS07815	COG2318	DinB family
SC10_RS07820	COG2076	Multidrug Resistance protein
SC10_RS07825	COG2076	Multidrug Resistance protein
SC10_RS07830	COG0788	formyltetrahydrofolate deformylase activity
SC10_RS07840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SC10_RS07845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SC10_RS07850	COG1764	response to oxidative stress
SC10_RS07855	COG1846	Transcriptional regulator
SC10_RS07860	COG1764	response to oxidative stress
SC10_RS07870	COG0590	tRNA wobble adenosine to inosine editing
SC10_RS07875	COG0406	alpha-ribazole phosphatase activity
SC10_RS07890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SC10_RS07895	COG1404	Belongs to the peptidase S8 family
SC10_RS07900	COG2239	Acts as a magnesium transporter
SC10_RS07910	COG0789	Transcriptional regulator
SC10_RS07920	COG1846	Transcriptional regulator
SC10_RS07925	COG1793	dna ligase
SC10_RS07925	COG3285	dna ligase
SC10_RS07930	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
SC10_RS07935	COG5001	Diguanylate cyclase
SC10_RS07935	COG3300	MHYT domain
SC10_RS07940	COG0586	Pfam SNARE associated Golgi protein
SC10_RS07945	COG0861	Integral membrane protein TerC family
SC10_RS07950	COG1191	sigma factor activity
SC10_RS07970	COG0501	Belongs to the peptidase M48B family
SC10_RS07975	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SC10_RS07980	COG0768	penicillin binding
SC10_RS07995	COG3594	Acyltransferase
SC10_RS08000	COG5002	protein histidine kinase activity
SC10_RS08005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SC10_RS08010	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
SC10_RS08015	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
SC10_RS08020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SC10_RS08025	COG0436	Aminotransferase
SC10_RS08030	COG1850	ribulose-bisphosphate carboxylase activity
SC10_RS08035	COG0235	Class ii aldolase
SC10_RS08035	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
SC10_RS08040	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
SC10_RS08040	COG0235	Class ii aldolase
SC10_RS08045	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
SC10_RS08050	COG0346	lactoylglutathione lyase activity
SC10_RS08055	COG3339	Conserved Protein
SC10_RS08065	COG3852	Histidine kinase
SC10_RS08070	COG1846	Transcriptional regulator
SC10_RS08075	COG1360	Flagellar Motor Protein
SC10_RS08080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SC10_RS08085	COG0542	response to heat
SC10_RS08090	COG3949	Membrane
SC10_RS08095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
SC10_RS08100	COG0720	synthase
SC10_RS08105	COG0602	queuosine metabolic process
SC10_RS08110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SC10_RS08120	COG0457	Tetratricopeptide repeat
SC10_RS08125	COG3739	integral membrane protein
SC10_RS08130	COG3655	Transcriptional regulator
SC10_RS08165	COG4873	Protein conserved in bacteria
SC10_RS08175	COG3773	Cell wall hydrolase
SC10_RS08180	COG2244	polysaccharide biosynthetic process
SC10_RS08185	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS08190	COG2217	Heavy metal translocating P-type atpase
SC10_RS08195	COG0006	proline dipeptidase activity
SC10_RS08205	COG1609	Transcriptional regulator
SC10_RS08210	COG3711	transcriptional antiterminator
SC10_RS08215	COG2190	(PTS) system
SC10_RS08215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS08215	COG1263	PTS System
SC10_RS08220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS08225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
SC10_RS08235	COG1533	DNA photolyase activity
SC10_RS08240	COG0456	acetyltransferase
SC10_RS08245	COG0840	transmembrane signaling receptor activity
SC10_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS08255	COG2084	Dehydrogenase
SC10_RS08260	COG2340	Cysteine-rich secretory protein family
SC10_RS08265	COG0768	penicillin binding
SC10_RS08270	COG4191	Histidine kinase
SC10_RS08275	COG0436	Aminotransferase
SC10_RS08280	COG1714	RDD family
SC10_RS08290	COG0835	chemotaxis
SC10_RS08290	COG0784	Response regulator, receiver
SC10_RS08300	COG2814	Major facilitator Superfamily
SC10_RS08305	COG1376	ErfK ybiS ycfS ynhG family protein
SC10_RS08310	COG1408	metallophosphoesterase
SC10_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS08320	COG2200	EAL domain
SC10_RS08330	COG4703	Protein of unknown function (DUF1797)
SC10_RS08335	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
SC10_RS08345	COG0517	IMP dehydrogenase activity
SC10_RS08350	COG0583	DNA-binding transcription factor activity
SC10_RS08355	COG0716	FMN binding
SC10_RS08365	COG0716	FMN binding
SC10_RS08370	COG2171	N-acyltransferase activity
SC10_RS08375	COG1473	amidohydrolase
SC10_RS08385	COG0450	alkyl hydroperoxide reductase
SC10_RS08390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS08405	COG0746	molybdenum cofactor guanylyltransferase activity
SC10_RS08410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
SC10_RS08415	COG0303	'Molybdopterin
SC10_RS08420	COG1763	Mo-molybdopterin cofactor biosynthetic process
SC10_RS08425	COG0314	molybdopterin synthase activity
SC10_RS08430	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
SC10_RS08440	COG1132	(ABC) transporter
SC10_RS08445	COG1132	(ABC) transporter
SC10_RS08455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SC10_RS08460	COG1136	(ABC) transporter
SC10_RS08465	COG0577	efflux transmembrane transporter activity
SC10_RS08470	COG1349	DNA-binding transcription factor activity
SC10_RS08475	COG1105	Belongs to the carbohydrate kinase PfkB family
SC10_RS08480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS08480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS08480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS08500	COG0488	(ABC) transporter
SC10_RS08510	COG2309	aminopeptidase activity
SC10_RS08515	COG1077	Cell shape determining protein MreB Mrl
SC10_RS08520	COG2002	toxin-antitoxin pair type II binding
SC10_RS08525	COG3852	Histidine kinase
SC10_RS08530	COG0569	domain protein
SC10_RS08535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
SC10_RS08540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SC10_RS08545	COG5503	Protein of unknown function (DUF1447)
SC10_RS08555	COG0561	phosphatase activity
SC10_RS08560	COG0242	peptide deformylase activity
SC10_RS08570	COG0497	DNA recombination
SC10_RS08575	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SC10_RS08580	COG0022	dehydrogenase e1 component
SC10_RS08585	COG0508	dehydrogenase complex catalyzes the overall conversion of
SC10_RS08590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SC10_RS08595	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS08600	COG1982	Orn Lys Arg decarboxylase major
SC10_RS08605	COG4476	Belongs to the UPF0223 family
SC10_RS08610	COG4493	Belongs to the UPF0637 family
SC10_RS08620	COG0483	inositol monophosphate 1-phosphatase activity
SC10_RS08640	COG1595	DNA-templated transcription, initiation
SC10_RS08655	COG1217	gtp-binding protein TYPA
SC10_RS08665	COG1846	Transcriptional regulator
SC10_RS08670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
SC10_RS08675	COG4896	Protein conserved in bacteria
SC10_RS08685	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
SC10_RS08690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SC10_RS08695	COG2066	Belongs to the glutaminase family
SC10_RS08700	COG4838	Belongs to the UPF0358 family
SC10_RS08705	COG0772	Belongs to the SEDS family
SC10_RS08710	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
SC10_RS08715	COG1612	heme a metabolic process
SC10_RS08720	COG0109	protoheme IX farnesyltransferase activity
SC10_RS08725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SC10_RS08725	COG2010	Cytochrome c
SC10_RS08730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SC10_RS08735	COG1845	cytochrome c oxidase, subunit III
SC10_RS08740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SC10_RS08745	COG3336	cytochrome c oxidase
SC10_RS08755	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
SC10_RS08760	COG2340	Cysteine-rich secretory protein family
SC10_RS08775	COG3679	Belongs to the UPF0342 family
SC10_RS08780	COG4471	UPF0298 protein
SC10_RS08785	COG0742	ribosomal rna small subunit methyltransferase
SC10_RS08790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
SC10_RS08795	COG3314	Sporulation integral membrane protein YlbJ
SC10_RS08800	COG3480	Lon protease (S16) C-terminal proteolytic domain
SC10_RS08805	COG1323	Belongs to the UPF0348 family
SC10_RS08810	COG1399	metal-binding, possibly nucleic acid-binding protein
SC10_RS08820	COG0454	-acetyltransferase
SC10_RS08825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
SC10_RS08830	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
SC10_RS08835	COG2001	Belongs to the MraZ family
SC10_RS08840	COG0275	rRNA processing
SC10_RS08845	COG4839	cell division protein FtsL
SC10_RS08850	COG0768	penicillin binding
SC10_RS08855	COG0768	penicillin binding
SC10_RS08860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SC10_RS08865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SC10_RS08870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SC10_RS08875	COG0772	Belongs to the SEDS family
SC10_RS08880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SC10_RS08885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
SC10_RS08890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SC10_RS08895	COG3879	Bacterial protein of unknown function (DUF881)
SC10_RS08900	COG3879	Bacterial protein of unknown function (DUF881)
SC10_RS08905	COG3856	small basic protein
SC10_RS08910	COG0849	cell division
SC10_RS08915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
SC10_RS08920	COG1404	Belongs to the peptidase S8 family
SC10_RS08920	COG4412	M6 family metalloprotease domain protein
SC10_RS08925	COG1404	Belongs to the peptidase S8 family
SC10_RS08925	COG4412	M6 family metalloprotease domain protein
SC10_RS08935	COG1191	sigma factor activity
SC10_RS08940	COG1191	sigma factor activity
SC10_RS08945	COG1119	ATPase activity
SC10_RS08950	COG0500	methyltransferase
SC10_RS08955	COG1873	PFAM PRC-barrel domain
SC10_RS08960	COG1496	oxidoreductase activity
SC10_RS08965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SC10_RS08970	COG1799	cell septum assembly
SC10_RS08975	COG0762	integral membrane protein
SC10_RS08980	COG2302	S4 RNA-binding domain
SC10_RS08985	COG3599	regulation of cell shape
SC10_RS08990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
SC10_RS08995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SC10_RS09000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SC10_RS09005	COG0564	pseudouridine synthase activity
SC10_RS09015	COG2233	PERMEase
SC10_RS09020	COG0540	Belongs to the ATCase OTCase family
SC10_RS09025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SC10_RS09030	COG0505	Belongs to the CarA family
SC10_RS09035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
SC10_RS09040	COG0543	2 iron, 2 sulfur cluster binding
SC10_RS09045	COG0167	dihydroorotate dehydrogenase activity
SC10_RS09050	COG0284	orotidine-5'-phosphate decarboxylase activity
SC10_RS09055	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SC10_RS09060	COG0175	sulfate reduction
SC10_RS09065	COG0306	phosphate transporter
SC10_RS09070	COG2046	Belongs to the sulfate adenylyltransferase family
SC10_RS09075	COG0529	Catalyzes the synthesis of activated sulfate
SC10_RS09080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
SC10_RS09085	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
SC10_RS09090	COG1648	precorrin-2 dehydrogenase activity
SC10_RS09100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SC10_RS09105	COG1561	YicC-like family, N-terminal region
SC10_RS09110	COG2052	Domain of unknown function (DUF370)
SC10_RS09115	COG0194	GDP metabolic process
SC10_RS09120	COG1758	RNA polymerase activity
SC10_RS09125	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SC10_RS09130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SC10_RS09135	COG0242	peptide deformylase activity
SC10_RS09140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
SC10_RS09145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SC10_RS09145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SC10_RS09150	COG0820	rRNA (adenine-C2-)-methyltransferase activity
SC10_RS09155	COG0631	protein serine/threonine phosphatase activity
SC10_RS09160	COG2815	serine threonine protein kinase
SC10_RS09160	COG0515	serine threonine protein kinase
SC10_RS09165	COG1162	GTPase activity
SC10_RS09170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SC10_RS09175	COG1564	THIamine pyrophosphokinase
SC10_RS09185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SC10_RS09190	COG1302	Protein conserved in bacteria
SC10_RS09195	COG1461	Dihydroxyacetone kinase
SC10_RS09200	COG1760	l-serine dehydratase
SC10_RS09205	COG1760	l-serine dehydratase
SC10_RS09210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SC10_RS09215	COG1349	DNA-binding transcription factor activity
SC10_RS09220	COG0416	fatty acid biosynthetic process
SC10_RS09225	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SC10_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS09235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SC10_RS09240	COG0571	ribonuclease III activity
SC10_RS09245	COG1196	nuclear chromosome segregation
SC10_RS09250	COG0552	protein localization to endoplasmic reticulum
SC10_RS09255	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
SC10_RS09260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SC10_RS09265	COG0228	four-way junction DNA binding
SC10_RS09270	COG1837	Belongs to the UPF0109 family
SC10_RS09280	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
SC10_RS09285	COG0336	Belongs to the RNA methyltransferase TrmD family
SC10_RS09290	COG0335	large ribosomal subunit rRNA binding
SC10_RS09295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SC10_RS09300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SC10_RS09310	COG2257	FlhB HrpN YscU SpaS Family
SC10_RS09315	COG0045	succinate-CoA ligase (ADP-forming) activity
SC10_RS09320	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
SC10_RS09325	COG0758	DNA mediated transformation
SC10_RS09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SC10_RS09335	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
SC10_RS09340	COG4974	Belongs to the 'phage' integrase family
SC10_RS09345	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
SC10_RS09350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
SC10_RS09355	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SC10_RS09360	COG1815	bacterial-type flagellum-dependent cell motility
SC10_RS09365	COG1558	bacterial-type flagellum-dependent cell motility
SC10_RS09370	COG1677	Flagellar hook-basal body complex protein FliE
SC10_RS09375	COG1766	The M ring may be actively involved in energy transduction
SC10_RS09380	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SC10_RS09385	COG1317	bacterial-type flagellum organization
SC10_RS09390	COG1157	protein secretion by the type III secretion system
SC10_RS09395	COG2882	bacterial-type flagellum organization
SC10_RS09400	COG3334	PFAM MgtE intracellular
SC10_RS09405	COG3144	bacterial-type flagellum assembly
SC10_RS09410	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
SC10_RS09415	COG4786	Flagellar basal body rod
SC10_RS09420	COG1582	Flagellar protein (FlbD)
SC10_RS09425	COG1580	Controls the rotational direction of flagella during chemotaxis
SC10_RS09430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SC10_RS09435	COG1776	CheC inhibitor of MCP methylation
SC10_RS09435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
SC10_RS09440	COG2201	protein-glutamate methylesterase activity
SC10_RS09445	COG3190	flagellar
SC10_RS09450	COG1338	Plays a role in the flagellum-specific transport system
SC10_RS09455	COG1987	bacterial-type flagellum assembly
SC10_RS09460	COG1684	flagellar biosynthetic protein fliR
SC10_RS09465	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SC10_RS09470	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
SC10_RS09475	COG1419	protein localization to endoplasmic reticulum
SC10_RS09480	COG0455	bacterial-type flagellum organization
SC10_RS09485	COG2201	protein-glutamate methylesterase activity
SC10_RS09490	COG0643	Histidine kinase
SC10_RS09490	COG2198	Histidine kinase
SC10_RS09495	COG0835	chemotaxis
SC10_RS09500	COG1776	CheC inhibitor of MCP methylation
SC10_RS09505	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
SC10_RS09510	COG1191	sigma factor activity
SC10_RS09520	COG0052	Belongs to the universal ribosomal protein uS2 family
SC10_RS09525	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
SC10_RS09530	COG0528	UMP kinase activity
SC10_RS09535	COG0233	cytoplasmic translational termination
SC10_RS09540	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SC10_RS09545	COG4589	Belongs to the CDS family
SC10_RS09550	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
SC10_RS09555	COG0750	zinc metalloprotease
SC10_RS09560	COG0442	prolyl-tRNA aminoacylation
SC10_RS09565	COG2176	DNA-directed DNA polymerase activity
SC10_RS09590	COG0779	Required for maturation of 30S ribosomal subunits
SC10_RS09595	COG0195	Participates in both transcription termination and antitermination
SC10_RS09600	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SC10_RS09605	COG1358	cellular component organization or biogenesis
SC10_RS09610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
SC10_RS09615	COG1550	Protein conserved in bacteria
SC10_RS09620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
SC10_RS09625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SC10_RS09630	COG0196	riboflavin kinase activity
SC10_RS09635	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
SC10_RS09640	COG1185	polyribonucleotide nucleotidyltransferase activity
SC10_RS09645	COG0726	polysaccharide deacetylase
SC10_RS09650	COG0612	Peptidase, M16
SC10_RS09655	COG1873	PFAM PRC-barrel domain
SC10_RS09660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SC10_RS09665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SC10_RS09670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SC10_RS09675	COG0527	aspartate kinase activity
SC10_RS09685	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
SC10_RS09690	COG0740	serine-type endopeptidase activity
SC10_RS09700	COG1674	ftsk spoiiie
SC10_RS09700	COG4980	gas vesicle protein
SC10_RS09705	COG2188	Transcriptional regulator
SC10_RS09710	COG2814	Major facilitator Superfamily
SC10_RS09715	COG0612	Peptidase, M16
SC10_RS09720	COG0612	Peptidase, M16
SC10_RS09725	COG0300	oxidoreductase activity
SC10_RS09740	COG1426	Protein conserved in bacteria
SC10_RS09745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SC10_RS09750	COG1546	Belongs to the CinA family
SC10_RS09750	COG1058	Belongs to the CinA family
SC10_RS09760	COG1418	mRNA catabolic process
SC10_RS09765	COG1692	metallophosphoesterase
SC10_RS09770	COG2359	stage V sporulation protein S
SC10_RS09780	COG1063	alcohol dehydrogenase
SC10_RS09790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SC10_RS09795	COG4550	Control of competence regulator ComK, YlbF/YmcA
SC10_RS09805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
SC10_RS09810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
SC10_RS09815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
SC10_RS09830	COG0457	Tetratricopeptide repeat
SC10_RS09835	COG5444	nuclease activity
SC10_RS09845	COG0523	cobalamin synthesis protein
SC10_RS09860	COG1231	oxidoreductase activity
SC10_RS09865	COG3619	membrane
SC10_RS09870	COG3263	regulation of cellular component size
SC10_RS09875	COG2814	Major facilitator Superfamily
SC10_RS09885	COG0393	Putative heavy-metal-binding
SC10_RS09890	COG0398	Pfam SNARE associated Golgi protein
SC10_RS09895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SC10_RS09900	COG1819	glycosyl
SC10_RS09905	COG0531	amino acid
SC10_RS09910	COG5577	PFAM Coat F domain
SC10_RS09920	COG1388	LysM domain
SC10_RS09920	COG3858	chitin binding
SC10_RS09925	COG1309	transcriptional regulator
SC10_RS09930	COG3631	Ketosteroid isomerase-related protein
SC10_RS09945	COG1764	response to oxidative stress
SC10_RS09950	COG2076	Multidrug Resistance protein
SC10_RS09955	COG2076	Multidrug Resistance protein
SC10_RS09970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
SC10_RS09975	COG1923	regulation of RNA biosynthetic process
SC10_RS09985	COG1780	Probably involved in ribonucleotide reductase function
SC10_RS09990	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SC10_RS09995	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SC10_RS10000	COG4112	unkown
SC10_RS10015	COG0735	belongs to the Fur family
SC10_RS10020	COG1802	Transcriptional regulator
SC10_RS10025	COG0697	spore germination
SC10_RS10055	COG1309	transcriptional regulator
SC10_RS10090	COG2814	Major facilitator Superfamily
SC10_RS10095	COG0457	Tetratricopeptide repeat
SC10_RS10105	COG4413	Urea transporter
SC10_RS10110	COG0831	urea catabolic process
SC10_RS10115	COG0832	Belongs to the urease beta subunit family
SC10_RS10125	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
SC10_RS10130	COG0830	nickel cation binding
SC10_RS10135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
SC10_RS10140	COG0829	nickel cation binding
SC10_RS10150	COG1695	Transcriptional regulator
SC10_RS10170	COG0464	growth
SC10_RS10175	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SC10_RS10180	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
SC10_RS10185	COG0789	Transcriptional regulator
SC10_RS10190	COG0174	glutamine synthetase
SC10_RS10210	COG0174	glutamine synthetase
SC10_RS10235	COG0490	domain, Protein
SC10_RS10240	COG0475	glutathione-regulated potassium exporter activity
SC10_RS10250	COG1073	alpha beta
SC10_RS10290	COG1309	transcriptional regulator
SC10_RS10295	COG2076	Multidrug Resistance protein
SC10_RS10300	COG2076	Multidrug Resistance protein
SC10_RS10305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SC10_RS10320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS10325	COG3546	catalase activity
SC10_RS10350	COG1846	Transcriptional regulator
SC10_RS10355	COG0346	lactoylglutathione lyase activity
SC10_RS10360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SC10_RS10365	COG0655	NAD(P)H dehydrogenase (quinone) activity
SC10_RS10390	COG3209	COG3209 Rhs family protein
SC10_RS10395	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
SC10_RS10400	COG1388	LysM domain
SC10_RS10405	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
SC10_RS10410	COG4224	UPF0291 protein
SC10_RS10415	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SC10_RS10425	COG3763	UPF0154 protein
SC10_RS10435	COG0785	Cytochrome C biogenesis protein
SC10_RS10440	COG2201	protein-glutamate methylesterase activity
SC10_RS10445	COG4846	Membrane protein involved in cytochrome C biogenesis
SC10_RS10455	COG0071	Belongs to the small heat shock protein (HSP20) family
SC10_RS10470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
SC10_RS10475	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS10490	COG0824	Thioesterase
SC10_RS10510	COG4841	protein insertion into membrane
SC10_RS10515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
SC10_RS10520	COG1832	CoA-binding protein
SC10_RS10525	COG0187	DNA topoisomerase II activity
SC10_RS10530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SC10_RS10535	COG1609	Transcriptional regulator
SC10_RS10550	COG2160	L-arabinose isomerase activity
SC10_RS10570	COG1115	amino acid carrier protein
SC10_RS10580	COG2181	nitrate reductase activity
SC10_RS10585	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SC10_RS10590	COG1140	nitrate reductase beta subunit
SC10_RS10595	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SC10_RS10610	COG0535	radical SAM domain protein
SC10_RS10615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SC10_RS10625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
SC10_RS10630	COG2223	nitrite transmembrane transporter activity
SC10_RS10650	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
SC10_RS10660	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
SC10_RS10670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SC10_RS10685	COG0477	Major facilitator Superfamily
SC10_RS10690	COG3420	alginic acid biosynthetic process
SC10_RS10695	COG1114	Component of the transport system for branched-chain amino acids
SC10_RS10705	COG1687	branched-chain amino acid
SC10_RS10710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
SC10_RS10715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS10745	COG1024	Enoyl-CoA hydratase
SC10_RS10750	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS10755	COG2084	Dehydrogenase
SC10_RS10760	COG1960	acyl-CoA dehydrogenase activity
SC10_RS10765	COG1482	cell wall glycoprotein biosynthetic process
SC10_RS10770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS10770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS10770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS10785	COG3711	transcriptional antiterminator
SC10_RS10785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS10800	COG1725	Transcriptional regulator
SC10_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS10810	COG1312	Catalyzes the dehydration of D-mannonate
SC10_RS10825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
SC10_RS10835	COG1609	Transcriptional regulator
SC10_RS10840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SC10_RS10845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
SC10_RS10850	COG0640	Transcriptional regulator
SC10_RS10855	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
SC10_RS10870	COG1649	PFAM Uncharacterised BCR, COG1649
SC10_RS10875	COG2404	hydrolase activity, acting on ester bonds
SC10_RS10880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SC10_RS10890	COG0438	transferase activity, transferring glycosyl groups
SC10_RS10895	COG2027	D-alanyl-D-alanine carboxypeptidase
SC10_RS10915	COG1309	transcriptional regulator
SC10_RS10920	COG1252	NADH dehydrogenase
SC10_RS10935	COG0166	Belongs to the GPI family
SC10_RS10945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SC10_RS10950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SC10_RS10955	COG1024	Enoyl-CoA hydratase
SC10_RS10960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SC10_RS10965	COG0511	ligase activity, forming carbon-carbon bonds
SC10_RS10970	COG0439	Biotin carboxylase
SC10_RS10975	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
SC10_RS10975	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS10980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS10990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS10995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS11000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS11005	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS11010	COG1960	acyl-CoA dehydrogenase activity
SC10_RS11015	COG2249	NAD(P)H dehydrogenase (quinone) activity
SC10_RS11020	COG1733	regulation of RNA biosynthetic process
SC10_RS11025	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
SC10_RS11030	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
SC10_RS11040	COG2323	membrane
SC10_RS11045	COG0306	phosphate transporter
SC10_RS11050	COG0175	sulfate reduction
SC10_RS11055	COG1809	phosphosulfolactate synthase activity
SC10_RS11060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS11065	COG4948	Mandelate Racemase Muconate Lactonizing
SC10_RS11070	COG2814	Major facilitator Superfamily
SC10_RS11075	COG0463	Glycosyl transferase, family 2
SC10_RS11090	COG0493	'glutamate synthase
SC10_RS11095	COG0070	glutamate synthase
SC10_RS11095	COG0067	glutamate synthase
SC10_RS11095	COG0069	glutamate synthase activity
SC10_RS11100	COG0583	DNA-binding transcription factor activity
SC10_RS11125	COG1132	(ABC) transporter
SC10_RS11135	COG0300	oxidoreductase activity
SC10_RS11140	COG3848	Pyruvate phosphate dikinase
SC10_RS11140	COG0574	Belongs to the PEP-utilizing enzyme family
SC10_RS11145	COG0477	Major facilitator Superfamily
SC10_RS11150	COG0243	molybdopterin cofactor binding
SC10_RS11155	COG1846	Transcriptional regulator
SC10_RS11160	COG2814	Major facilitator Superfamily
SC10_RS11165	COG0531	amino acid
SC10_RS11175	COG0531	amino acid
SC10_RS11180	COG0531	amino acid
SC10_RS11185	COG0697	spore germination
SC10_RS11190	COG0488	(ABC) transporter
SC10_RS11195	COG0840	transmembrane signaling receptor activity
SC10_RS11200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SC10_RS11205	COG1404	Belongs to the peptidase S8 family
SC10_RS11215	COG1309	transcriptional regulator
SC10_RS11220	COG1846	Transcriptional regulator
SC10_RS11250	COG1309	transcriptional regulator
SC10_RS11255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS11270	COG2378	regulation of single-species biofilm formation
SC10_RS11280	COG0640	Transcriptional regulator
SC10_RS11285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS11295	COG0531	amino acid
SC10_RS11300	COG0741	lytic transglycosylase activity
SC10_RS11305	COG1086	Polysaccharide biosynthesis protein
SC10_RS11320	COG0438	transferase activity, transferring glycosyl groups
SC10_RS11325	COG2322	membrane
SC10_RS11340	COG1619	proteins homologs of microcin C7 resistance protein MccF
SC10_RS11345	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS11350	COG3584	3D domain protein
SC10_RS11350	COG1388	LysM domain
SC10_RS11355	COG0514	ATP-dependent DNA helicase (RecQ)
SC10_RS11370	COG2315	Protein conserved in bacteria
SC10_RS11375	COG5444	nuclease activity
SC10_RS11380	COG2427	Protein of unknown function (DUF1641)
SC10_RS11385	COG3383	formate dehydrogenase (NAD+) activity
SC10_RS11410	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
SC10_RS11435	COG2350	Protein conserved in bacteria
SC10_RS11460	COG0402	S-adenosylhomocysteine deaminase activity
SC10_RS11475	COG2267	carboxylic ester hydrolase activity
SC10_RS11485	COG1280	lysine exporter protein (LysE YggA)
SC10_RS11490	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
SC10_RS11500	COG0574	Belongs to the PEP-utilizing enzyme family
SC10_RS11500	COG3848	Pyruvate phosphate dikinase
SC10_RS11520	COG2318	DinB family
SC10_RS11525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SC10_RS11540	COG0156	8-amino-7-oxononanoate synthase activity
SC10_RS11545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SC10_RS11560	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS11580	COG1657	PFAM Prenyltransferase squalene oxidase
SC10_RS11585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SC10_RS11595	COG0733	neurotransmitter:sodium symporter activity
SC10_RS11600	COG0385	Bile acid
SC10_RS11605	COG0508	dehydrogenase complex catalyzes the overall conversion of
SC10_RS11610	COG0567	Dehydrogenase, E1 component
SC10_RS11615	COG4548	von Willebrand factor, type A
SC10_RS11620	COG0714	Associated with various cellular activities
SC10_RS11625	COG2032	superoxide dismutase activity
SC10_RS11630	COG1388	LysM domain
SC10_RS11630	COG0791	NLP P60 protein
SC10_RS11635	COG0534	Mate efflux family protein
SC10_RS11640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SC10_RS11645	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SC10_RS11655	COG2962	Rard protein
SC10_RS11665	COG4305	rare lipoprotein A
SC10_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS11680	COG1733	regulation of RNA biosynthetic process
SC10_RS11685	COG0778	Nitroreductase
SC10_RS11690	COG0400	carboxylic ester hydrolase activity
SC10_RS11700	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS11705	COG0793	Belongs to the peptidase S41A family
SC10_RS11705	COG3409	Peptidoglycan-binding domain 1 protein
SC10_RS11710	COG2226	methyltransferase
SC10_RS11720	COG1876	peptidase activity
SC10_RS11725	COG0813	purine-nucleoside phosphorylase activity
SC10_RS11730	COG0701	Predicted permease
SC10_RS11745	COG0671	phosphoesterase, PA-phosphatase related
SC10_RS11760	COG4479	Belongs to the UPF0346 family
SC10_RS11770	COG1509	lysine 2,3-aminomutase activity
SC10_RS11775	COG0456	acetyltransferase
SC10_RS11780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SC10_RS11785	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
SC10_RS11790	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
SC10_RS11795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
SC10_RS11810	COG0456	acetyltransferase
SC10_RS11815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SC10_RS11820	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SC10_RS11825	COG1846	Transcriptional regulator
SC10_RS11840	COG0534	Mate efflux family protein
SC10_RS11855	COG4698	Protein conserved in bacteria
SC10_RS11860	COG2755	lipolytic protein G-D-S-L family
SC10_RS11865	COG1999	signal sequence binding
SC10_RS11880	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SC10_RS11885	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SC10_RS11890	COG1272	protein, Hemolysin III
SC10_RS11895	COG0204	Acyl-transferase
SC10_RS11900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SC10_RS11910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SC10_RS11920	COG2521	methyltransferase
SC10_RS11920	COG2136	Putative SAM-dependent methyltransferase
SC10_RS11930	COG0129	dihydroxy-acid dehydratase activity
SC10_RS11935	COG1413	lyase activity
SC10_RS11940	COG1418	mRNA catabolic process
SC10_RS11945	COG0386	Belongs to the glutathione peroxidase family
SC10_RS11950	COG2759	Belongs to the formate--tetrahydrofolate ligase family
SC10_RS11955	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
SC10_RS11960	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SC10_RS11970	COG1278	Cold shock
SC10_RS11990	COG0328	RNA-DNA hybrid ribonuclease activity
SC10_RS11995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
SC10_RS12000	COG0328	RNA-DNA hybrid ribonuclease activity
SC10_RS12010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SC10_RS12020	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SC10_RS12030	COG1755	Isoprenylcysteine carboxyl methyltransferase
SC10_RS12035	COG3424	synthase
SC10_RS12045	COG2233	PERMEase
SC10_RS12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SC10_RS12055	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
SC10_RS12060	COG1199	ATP-dependent helicase activity
SC10_RS12075	COG0116	Belongs to the methyltransferase superfamily
SC10_RS12080	COG3599	regulation of cell shape
SC10_RS12085	COG4474	Belongs to the UPF0398 family
SC10_RS12095	COG3359	exonuclease
SC10_RS12100	COG1205	dead DEAH box helicase
SC10_RS12100	COG1111	helicase
SC10_RS12105	COG2190	(PTS) system
SC10_RS12110	COG0071	Belongs to the small heat shock protein (HSP20) family
SC10_RS12145	COG3331	DNA recombination
SC10_RS12150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SC10_RS12150	COG4499	WXG100 protein secretion system (Wss), protein YukC
SC10_RS12160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SC10_RS12165	COG3935	DnaD domain protein
SC10_RS12170	COG0017	Asparaginyl-tRNA synthetase
SC10_RS12175	COG0436	Aminotransferase
SC10_RS12180	COG5353	protein conserved in bacteria
SC10_RS12185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
SC10_RS12185	COG1199	ATP-dependent helicase activity
SC10_RS12190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
SC10_RS12195	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
SC10_RS12200	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
SC10_RS12215	COG0617	tRNA 3'-terminal CCA addition
SC10_RS12220	COG0438	transferase activity, transferring glycosyl groups
SC10_RS12225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
SC10_RS12230	COG1803	Methylglyoxal synthase
SC10_RS12235	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
SC10_RS12240	COG1694	Mazg nucleotide pyrophosphohydrolase
SC10_RS12245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS12255	COG4347	Protein of unknown function (DUF1405)
SC10_RS12260	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SC10_RS12260	COG2010	Cytochrome c
SC10_RS12265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
SC10_RS12270	COG0723	plastoquinol--plastocyanin reductase activity
SC10_RS12280	COG5582	Belongs to the UPF0302 family
SC10_RS12285	COG0457	Tetratricopeptide repeat
SC10_RS12290	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
SC10_RS12295	COG0287	Prephenate dehydrogenase
SC10_RS12300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
SC10_RS12305	COG0159	tryptophan synthase activity
SC10_RS12310	COG0133	tryptophan synthase activity
SC10_RS12315	COG0135	phosphoribosylanthranilate isomerase activity
SC10_RS12320	COG0134	indole-3-glycerol-phosphate synthase activity
SC10_RS12325	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SC10_RS12330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SC10_RS12335	COG4401	Chorismate mutase type I
SC10_RS12340	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
SC10_RS12345	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
SC10_RS12350	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
SC10_RS12355	COG0105	UTP biosynthetic process
SC10_RS12360	COG0142	geranyltranstransferase activity
SC10_RS12365	COG2226	methyltransferase
SC10_RS12370	COG0142	geranyltranstransferase activity
SC10_RS12385	COG0776	regulation of translation
SC10_RS12390	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
SC10_RS12405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
SC10_RS12410	COG1160	GTP binding
SC10_RS12430	COG1304	FMN binding
SC10_RS12435	COG0539	negative regulation of cytoplasmic translation
SC10_RS12440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
SC10_RS12445	COG2959	enzyme of heme biosynthesis
SC10_RS12450	COG3773	Cell wall hydrolase
SC10_RS12450	COG3409	Peptidoglycan-binding domain 1 protein
SC10_RS12455	COG2339	peptidase activity
SC10_RS12465	COG0492	ferredoxin-NADP+ reductase activity
SC10_RS12470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SC10_RS12475	COG4862	establishment of competence for transformation
SC10_RS12480	COG1408	metallophosphoesterase
SC10_RS12490	COG1388	LysM domain
SC10_RS12495	COG1266	CAAX protease self-immunity
SC10_RS12500	COG0514	ATP-dependent DNA helicase (RecQ)
SC10_RS12505	COG4955	Helix-turn-helix domain
SC10_RS12510	COG1141	Ferredoxin
SC10_RS12515	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SC10_RS12520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
SC10_RS12525	COG0739	heme binding
SC10_RS12535	COG1595	DNA-templated transcription, initiation
SC10_RS12540	COG1316	TRANSCRIPTIONal
SC10_RS12555	COG5002	protein histidine kinase activity
SC10_RS12560	COG0745	RESPONSE REGULATOR receiver
SC10_RS12565	COG5002	protein histidine kinase activity
SC10_RS12570	COG0745	RESPONSE REGULATOR receiver
SC10_RS12575	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SC10_RS12580	COG1333	cytochrome c biogenesis protein
SC10_RS12585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS12590	COG1187	pseudouridine synthase activity
SC10_RS12595	COG0700	Nucleoside recognition
SC10_RS12600	COG2715	membrane protein required for spore maturation
SC10_RS12605	COG1686	Belongs to the peptidase S11 family
SC10_RS12615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
SC10_RS12620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
SC10_RS12625	COG1547	Domain of unknown function (DUF309)
SC10_RS12630	COG0456	acetyltransferase
SC10_RS12635	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
SC10_RS12640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SC10_RS12640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SC10_RS12645	COG0307	riboflavin synthase, alpha
SC10_RS12650	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SC10_RS12650	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
SC10_RS12670	COG0457	Tetratricopeptide repeat
SC10_RS12675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
SC10_RS12680	COG4086	secreted protein
SC10_RS12685	COG4195	phage-related replication protein
SC10_RS12695	COG0019	diaminopimelate decarboxylase activity
SC10_RS12705	COG0697	spore germination
SC10_RS12720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
SC10_RS12755	COG1686	Belongs to the peptidase S11 family
SC10_RS12760	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SC10_RS12765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
SC10_RS12770	COG4974	Belongs to the 'phage' integrase family
SC10_RS12780	COG0735	belongs to the Fur family
SC10_RS12785	COG1300	Membrane
SC10_RS12790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS12800	COG1953	Uracil, thiamine, allantoin
SC10_RS12815	COG2153	protein acetylation
SC10_RS12820	COG1379	DNA repair
SC10_RS12825	COG0494	nUDIX hydrolase
SC10_RS12830	COG1309	transcriptional regulator
SC10_RS12840	COG0667	Aldo Keto reductase
SC10_RS12850	COG1073	alpha beta
SC10_RS12860	COG4918	Iron-sulphur cluster biosynthesis
SC10_RS12870	COG0456	acetyltransferase
SC10_RS12870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SC10_RS12875	COG2329	Antibiotic biosynthesis monooxygenase
SC10_RS12880	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
SC10_RS12890	COG0747	negative chemotaxis
SC10_RS12895	COG0601	transmembrane transport
SC10_RS12900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS12905	COG0444	Belongs to the ABC transporter superfamily
SC10_RS12915	COG0534	Mate efflux family protein
SC10_RS12930	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SC10_RS12940	COG2211	Major facilitator Superfamily
SC10_RS12945	COG0346	lactoylglutathione lyase activity
SC10_RS12950	COG1072	(Pantothenic acid kinase))
SC10_RS12960	COG3842	ATPase activity
SC10_RS12985	COG2205	protein histidine kinase activity
SC10_RS12990	COG0745	RESPONSE REGULATOR receiver
SC10_RS13010	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
SC10_RS13015	COG2814	Major facilitator Superfamily
SC10_RS13025	COG4195	phage-related replication protein
SC10_RS13030	COG0300	oxidoreductase activity
SC10_RS13035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS13040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SC10_RS13045	COG4187	Peptidase family M20/M25/M40
SC10_RS13050	COG1902	pentaerythritol trinitrate reductase activity
SC10_RS13055	COG0596	Alpha beta hydrolase
SC10_RS13060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SC10_RS13065	COG1234	tRNA 3'-trailer cleavage
SC10_RS13070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SC10_RS13085	COG2358	TRAP transporter, solute receptor (TAXI family
SC10_RS13090	COG2188	Transcriptional regulator
SC10_RS13095	COG2723	6-phospho-beta-galactosidase activity
SC10_RS13100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS13105	COG1447	Phosphotransferase system cellobiose-specific component IIA
SC10_RS13110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS13115	COG1785	Belongs to the alkaline phosphatase family
SC10_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS13125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SC10_RS13130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SC10_RS13140	COG0706	membrane insertase activity
SC10_RS13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
SC10_RS13150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
SC10_RS13155	COG4129	membrane
SC10_RS13160	COG1126	abc transporter atp-binding protein
SC10_RS13165	COG0765	amino acid transport
SC10_RS13170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SC10_RS13180	COG1597	lipid kinase activity
SC10_RS13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
SC10_RS13190	COG0022	dehydrogenase e1 component
SC10_RS13195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SC10_RS13200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SC10_RS13205	COG3426	butyrate kinase activity
SC10_RS13215	COG0280	phosphate acetyltransferase
SC10_RS13220	COG3290	protein histidine kinase activity
SC10_RS13220	COG3829	transcription factor binding
SC10_RS13230	COG0584	glycerophosphoryl diester phosphodiesterase
SC10_RS13235	COG0860	N-Acetylmuramoyl-L-alanine amidase
SC10_RS13260	COG0745	RESPONSE REGULATOR receiver
SC10_RS13265	COG0750	zinc metalloprotease
SC10_RS13270	COG0497	DNA recombination
SC10_RS13275	COG1438	arginine binding
SC10_RS13280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SC10_RS13285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SC10_RS13290	COG0142	geranyltranstransferase activity
SC10_RS13295	COG1722	exodeoxyribonuclease VII activity
SC10_RS13300	COG1570	exodeoxyribonuclease VII activity
SC10_RS13305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SC10_RS13310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SC10_RS13320	COG1302	Protein conserved in bacteria
SC10_RS13325	COG0439	Biotin carboxylase
SC10_RS13330	COG0511	ligase activity, forming carbon-carbon bonds
SC10_RS13370	COG3854	ATPases associated with a variety of cellular activities
SC10_RS13380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
SC10_RS13385	COG0006	proline dipeptidase activity
SC10_RS13390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
SC10_RS13400	COG3872	metal-dependent enzyme
SC10_RS13410	COG1752	Esterase of the alpha-beta hydrolase superfamily
SC10_RS13415	COG1321	iron dependent repressor
SC10_RS13420	COG0095	Lipoate-protein ligase
SC10_RS13425	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SC10_RS13430	COG2113	Glycine betaine
SC10_RS13435	COG4176	ABC-type proline glycine betaine transport system permease component
SC10_RS13440	COG0517	IMP dehydrogenase activity
SC10_RS13440	COG4175	Glycine betaine
SC10_RS13445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SC10_RS13450	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
SC10_RS13455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
SC10_RS13465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SC10_RS13490	COG0681	Belongs to the peptidase S26 family
SC10_RS13515	COG4940	Competence protein ComGF
SC10_RS13525	COG4970	Tfp pilus assembly protein FimT
SC10_RS13530	COG4537	Required for transformation and DNA binding
SC10_RS13535	COG1459	type II secretion system
SC10_RS13540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SC10_RS13545	COG1366	Belongs to the anti-sigma-factor antagonist family
SC10_RS13555	COG1393	Belongs to the ArsC family
SC10_RS13565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS13575	COG0011	TIGRFAM Protein of
SC10_RS13585	COG2866	Carboxypeptidase
SC10_RS13590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS13595	COG1368	sulfuric ester hydrolase activity
SC10_RS13600	COG1940	carbohydrate kinase activity
SC10_RS13605	COG4483	Protein conserved in bacteria
SC10_RS13610	COG0697	spore germination
SC10_RS13615	COG0457	Tetratricopeptide repeat
SC10_RS13615	COG0705	Rhomboid family
SC10_RS13620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SC10_RS13625	COG0438	transferase activity, transferring glycosyl groups
SC10_RS13640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SC10_RS13680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SC10_RS13685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SC10_RS13690	COG0581	inorganic phosphate transmembrane transporter activity
SC10_RS13695	COG0573	inorganic phosphate transmembrane transporter activity
SC10_RS13700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SC10_RS13705	COG0768	penicillin binding
SC10_RS13710	COG0477	Major facilitator Superfamily
SC10_RS13715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SC10_RS13720	COG2839	Protein conserved in bacteria
SC10_RS13725	COG5521	maltodextrose utilization protein MalA
SC10_RS13730	COG1388	LysM domain
SC10_RS13735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
SC10_RS13740	COG4709	membrane
SC10_RS13745	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
SC10_RS13750	COG0735	belongs to the Fur family
SC10_RS13755	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SC10_RS13760	COG1121	(ABC) transporter
SC10_RS13765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS13775	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
SC10_RS13780	COG0513	Belongs to the DEAD box helicase family
SC10_RS13790	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
SC10_RS13795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SC10_RS13800	COG2384	SAM-dependent methyltransferase
SC10_RS13825	COG5444	nuclease activity
SC10_RS13840	COG2010	Cytochrome c
SC10_RS13845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SC10_RS13850	COG0358	DNA primase activity
SC10_RS13855	COG1671	Belongs to the UPF0178 family
SC10_RS13860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
SC10_RS13865	COG0517	IMP dehydrogenase activity
SC10_RS13870	COG0751	glycine-tRNA ligase activity
SC10_RS13875	COG0752	glycyl-tRNA synthetase alpha subunit
SC10_RS13880	COG1381	Involved in DNA repair and RecF pathway recombination
SC10_RS13890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
SC10_RS13895	COG0295	cytidine deaminase activity
SC10_RS13900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SC10_RS13905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
SC10_RS13910	COG1480	7TM receptor with intracellular HD hydrolase
SC10_RS13915	COG1702	phosphate starvation-inducible protein PhoH
SC10_RS13920	COG0561	phosphatase activity
SC10_RS13935	COG4864	UPF0365 protein
SC10_RS13940	COG1030	water channel activity
SC10_RS13945	COG1610	YqeY-like protein
SC10_RS13950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
SC10_RS13955	COG1283	sodium-dependent phosphate transmembrane transporter activity
SC10_RS13960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SC10_RS13965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
SC10_RS13970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SC10_RS13975	COG2264	protein methyltransferase activity
SC10_RS13980	COG0484	heat shock protein binding
SC10_RS13985	COG0443	Heat shock 70 kDa protein
SC10_RS13990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
SC10_RS13995	COG1420	regulation of RNA biosynthetic process
SC10_RS14000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SC10_RS14005	COG0481	GTPase activity
SC10_RS14015	COG0860	N-Acetylmuramoyl-L-alanine amidase
SC10_RS14020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
SC10_RS14025	COG0268	Binds directly to 16S ribosomal RNA
SC10_RS14035	COG1733	regulation of RNA biosynthetic process
SC10_RS14040	COG2249	NAD(P)H dehydrogenase (quinone) activity
SC10_RS14045	COG1466	dna polymerase III delta subunit
SC10_RS14055	COG0658	competence protein
SC10_RS14055	COG2333	competence protein COMEC
SC10_RS14060	COG2131	deaminase
SC10_RS14065	COG1596	polysaccharide export
SC10_RS14065	COG1555	photosystem II stabilization
SC10_RS14070	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SC10_RS14075	COG2226	methyltransferase
SC10_RS14080	COG0799	negative regulation of ribosome biogenesis
SC10_RS14085	COG1713	HD superfamily hydrolase involved in NAD metabolism
SC10_RS14090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SC10_RS14095	COG1534	Rna-binding protein
SC10_RS14100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
SC10_RS14105	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SC10_RS14110	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
SC10_RS14120	COG2755	lipolytic protein G-D-S-L family
SC10_RS14130	COG5609	conserved protein (DUF2294)
SC10_RS14135	COG3383	formate dehydrogenase (NAD+) activity
SC10_RS14140	COG2427	Protein of unknown function (DUF1641)
SC10_RS14180	COG3223	Belongs to the PsiE family
SC10_RS14185	COG0642	Histidine kinase
SC10_RS14185	COG5002	protein histidine kinase activity
SC10_RS14190	COG0745	RESPONSE REGULATOR receiver
SC10_RS14195	COG2311	Membrane
SC10_RS14200	COG0454	-acetyltransferase
SC10_RS14215	COG3616	Alanine racemase, N-terminal domain
SC10_RS14220	COG0251	oxidation-reduction process
SC10_RS14235	COG0251	oxidation-reduction process
SC10_RS14255	COG4978	Transcriptional regulator
SC10_RS14255	COG0789	Transcriptional regulator
SC10_RS14270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
SC10_RS14275	COG2828	Protein conserved in bacteria
SC10_RS14285	COG2181	nitrate reductase activity
SC10_RS14290	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
SC10_RS14295	COG1140	nitrate reductase beta subunit
SC10_RS14300	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
SC10_RS14305	COG2223	nitrite transmembrane transporter activity
SC10_RS14315	COG3226	Transcriptional regulator
SC10_RS14350	COG2197	response regulator
SC10_RS14355	COG4585	Histidine kinase
SC10_RS14360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS14365	COG0730	response to heat
SC10_RS14370	COG0425	Belongs to the sulfur carrier protein TusA family
SC10_RS14375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SC10_RS14375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS14380	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SC10_RS14380	COG0425	Belongs to the sulfur carrier protein TusA family
SC10_RS14385	COG2210	Belongs to the sulfur carrier protein TusA family
SC10_RS14390	COG1937	Protein conserved in bacteria
SC10_RS14410	COG1942	4-Oxalocrotonate Tautomerase
SC10_RS14415	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
SC10_RS14420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
SC10_RS14425	COG1733	regulation of RNA biosynthetic process
SC10_RS14430	COG3239	Fatty acid desaturase
SC10_RS14435	COG4585	Histidine kinase
SC10_RS14440	COG2197	response regulator
SC10_RS14445	COG0492	ferredoxin-NADP+ reductase activity
SC10_RS14450	COG0747	negative chemotaxis
SC10_RS14455	COG0601	transmembrane transport
SC10_RS14460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SC10_RS14465	COG0444	Belongs to the ABC transporter superfamily
SC10_RS14470	COG4608	Belongs to the ABC transporter superfamily
SC10_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS14500	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
SC10_RS14515	COG2124	cytochrome p450
SC10_RS14520	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS14525	COG2211	Major facilitator Superfamily
SC10_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS14540	COG1621	beta-fructofuranosidase activity
SC10_RS14545	COG3716	PTS system mannose fructose sorbose family IID component
SC10_RS14550	COG3715	PTS system
SC10_RS14555	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS14560	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS14565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
SC10_RS14565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
SC10_RS14585	COG2169	Transcriptional regulator
SC10_RS14590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SC10_RS14595	COG2205	protein histidine kinase activity
SC10_RS14605	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
SC10_RS14610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
SC10_RS14615	COG0656	L-ascorbic acid biosynthetic process
SC10_RS14620	COG2814	Major facilitator Superfamily
SC10_RS14625	COG1733	regulation of RNA biosynthetic process
SC10_RS14630	COG3340	Belongs to the peptidase S51 family
SC10_RS14640	COG1587	Uroporphyrinogen-III synthase
SC10_RS14650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS14655	COG0583	DNA-binding transcription factor activity
SC10_RS14660	COG2814	Major facilitator Superfamily
SC10_RS14670	COG2124	cytochrome p450
SC10_RS14670	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
SC10_RS14675	COG1309	transcriptional regulator
SC10_RS14680	COG1404	Belongs to the peptidase S8 family
SC10_RS14685	COG2226	methyltransferase
SC10_RS14700	COG0626	cystathionine gamma-synthase activity
SC10_RS14705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SC10_RS14710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SC10_RS14715	COG2226	methyltransferase
SC10_RS14730	COG0768	penicillin binding
SC10_RS14735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
SC10_RS14740	COG0572	uridine kinase
SC10_RS14745	COG0826	peptidase U32
SC10_RS14750	COG0826	peptidase U32
SC10_RS14755	COG4122	O-methyltransferase activity
SC10_RS14760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SC10_RS14765	COG3906	Belongs to the UPF0473 family
SC10_RS14770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
SC10_RS14775	COG4472	Bacterial protein of unknown function (DUF965)
SC10_RS14780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
SC10_RS14785	COG0628	permease
SC10_RS14795	COG3881	PFAM PRC-barrel domain
SC10_RS14800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SC10_RS14805	COG0457	Tetratricopeptide repeat
SC10_RS14810	COG0482	sulfurtransferase activity
SC10_RS14815	COG1104	cysteine desulfurase activity
SC10_RS14820	COG1959	2 iron, 2 sulfur cluster binding
SC10_RS14825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SC10_RS14830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
SC10_RS14835	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
SC10_RS14840	COG0124	histidyl-tRNA synthetase
SC10_RS14845	COG3103	Sh3 type 3 domain protein
SC10_RS14845	COG4991	sh3 domain protein
SC10_RS14845	COG0860	N-Acetylmuramoyl-L-alanine amidase
SC10_RS14850	COG1490	D-aminoacyl-tRNA deacylase activity
SC10_RS14855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SC10_RS14860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SC10_RS14865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SC10_RS14865	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SC10_RS14870	COG5416	Lipopolysaccharide assembly protein A domain
SC10_RS14875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SC10_RS14875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
SC10_RS14885	COG2244	polysaccharide biosynthetic process
SC10_RS14890	COG2323	membrane
SC10_RS14900	COG1862	Preprotein translocase
SC10_RS14905	COG0343	queuine tRNA-ribosyltransferase activity
SC10_RS14910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SC10_RS14920	COG2255	four-way junction helicase activity
SC10_RS14925	COG0632	four-way junction helicase activity
SC10_RS14935	COG2112	serine threonine protein kinase
SC10_RS14945	COG2318	DinB family
SC10_RS14950	COG4195	phage-related replication protein
SC10_RS14965	COG0217	transcriptional regulatory protein
SC10_RS14975	COG1388	LysM domain
SC10_RS14980	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
SC10_RS14985	COG0157	Belongs to the NadC ModD family
SC10_RS14990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
SC10_RS14995	COG1104	cysteine desulfurase activity
SC10_RS15000	COG1827	regulation of RNA biosynthetic process
SC10_RS15005	COG0077	Prephenate dehydratase
SC10_RS15010	COG4492	Belongs to the UPF0735 family
SC10_RS15015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
SC10_RS15020	COG3290	protein histidine kinase activity
SC10_RS15025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
SC10_RS15030	COG2868	ribosomal protein
SC10_RS15035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
SC10_RS15040	COG1994	Peptidase M50
SC10_RS15045	COG0739	heme binding
SC10_RS15050	COG3832	glyoxalase III activity
SC10_RS15055	COG0640	Transcriptional regulator
SC10_RS15060	COG2894	cell division
SC10_RS15065	COG0850	regulation of cytokinetic process
SC10_RS15070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
SC10_RS15080	COG1077	Cell shape determining protein MreB Mrl
SC10_RS15085	COG2003	Belongs to the UPF0758 family
SC10_RS15090	COG0424	maF-like protein
SC10_RS15100	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SC10_RS15105	COG0285	dihydrofolate synthase activity
SC10_RS15110	COG0525	valine-tRNA ligase activity
SC10_RS15120	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SC10_RS15125	COG1388	LysM domain
SC10_RS15130	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
SC10_RS15135	COG0113	porphobilinogen synthase activity
SC10_RS15140	COG1587	Uroporphyrinogen-III synthase
SC10_RS15145	COG0181	hydroxymethylbilane synthase activity
SC10_RS15150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
SC10_RS15155	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
SC10_RS15165	COG0218	Necessary for normal cell division and for the maintenance of normal septation
SC10_RS15170	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
SC10_RS15175	COG0470	DNA polymerase III
SC10_RS15175	COG1067	ATP-dependent peptidase activity
SC10_RS15180	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
SC10_RS15185	COG0544	peptidyl-prolyl cis-trans isomerase activity
SC10_RS15190	COG0457	Tetratricopeptide repeat
SC10_RS15190	COG1477	protein flavinylation
SC10_RS15195	COG0066	3-isopropylmalate dehydratase activity
SC10_RS15200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
SC10_RS15205	COG0473	3-isopropylmalate dehydrogenase activity
SC10_RS15210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
SC10_RS15215	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
SC10_RS15220	COG0440	acetolactate synthase activity
SC10_RS15225	COG0028	Belongs to the TPP enzyme family
SC10_RS15230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SC10_RS15240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SC10_RS15260	COG0622	Phosphoesterase
SC10_RS15265	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SC10_RS15270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
SC10_RS15275	COG5401	PFAM Sporulation and spore germination
SC10_RS15280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
SC10_RS15285	COG1846	Transcriptional regulator
SC10_RS15290	COG2197	response regulator
SC10_RS15295	COG4221	oxidoreductase activity
SC10_RS15300	COG0824	Thioesterase
SC10_RS15305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
SC10_RS15310	COG1053	succinate dehydrogenase
SC10_RS15315	COG2009	succinate dehydrogenase
SC10_RS15320	COG1719	4-vinyl reductase, 4VR
SC10_RS15325	COG0527	aspartate kinase activity
SC10_RS15330	COG0322	excinuclease ABC activity
SC10_RS15335	COG3118	belongs to the thioredoxin family
SC10_RS15340	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
SC10_RS15345	COG2086	electron transfer activity
SC10_RS15350	COG1024	Enoyl-CoA hydratase
SC10_RS15355	COG1309	transcriptional regulator
SC10_RS15360	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS15365	COG3766	membrane
SC10_RS15370	COG1193	negative regulation of DNA recombination
SC10_RS15375	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SC10_RS15375	COG1796	DNA polymerase
SC10_RS15380	COG1286	toxin biosynthetic process
SC10_RS15385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
SC10_RS15390	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
SC10_RS15405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SC10_RS15405	COG0072	phenylalanine-tRNA ligase activity
SC10_RS15410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
SC10_RS15415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SC10_RS15425	COG1966	Carbon starvation protein
SC10_RS15430	COG1309	transcriptional regulator
SC10_RS15435	COG3402	PFAM membrane-flanked domain
SC10_RS15455	COG0395	ABC-type sugar transport system, permease component
SC10_RS15460	COG1175	transmembrane transport
SC10_RS15465	COG1653	transport
SC10_RS15470	COG0371	Dehydrogenase
SC10_RS15475	COG0235	Class ii aldolase
SC10_RS15480	COG1069	ribulokinase activity
SC10_RS15485	COG2160	L-arabinose isomerase activity
SC10_RS15490	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS15495	COG1363	Peptidase, m42
SC10_RS15505	COG3326	Membrane
SC10_RS15510	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
SC10_RS15515	COG0291	Belongs to the bacterial ribosomal protein bL35 family
SC10_RS15520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
SC10_RS15525	COG1346	cytolysis
SC10_RS15535	COG3540	Alkaline phosphatase
SC10_RS15540	COG3279	Response regulator of the LytR AlgR family
SC10_RS15545	COG3275	phosphorelay sensor kinase activity
SC10_RS15555	COG1011	Hydrolase
SC10_RS15560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
SC10_RS15570	COG0398	Pfam SNARE associated Golgi protein
SC10_RS15575	COG1484	DNA-dependent DNA replication
SC10_RS15580	COG3611	Membrane attachment protein
SC10_RS15585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SC10_RS15595	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
SC10_RS15600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SC10_RS15605	COG3866	Pectate lyase
SC10_RS15610	COG0237	dephospho-CoA kinase activity
SC10_RS15615	COG1971	Probably functions as a manganese efflux pump
SC10_RS15620	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SC10_RS15625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SC10_RS15625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SC10_RS15630	COG5002	protein histidine kinase activity
SC10_RS15635	COG0745	RESPONSE REGULATOR receiver
SC10_RS15640	COG0039	L-malate dehydrogenase activity
SC10_RS15645	COG0538	isocitrate dehydrogenase activity
SC10_RS15650	COG0372	Belongs to the citrate synthase family
SC10_RS15660	COG2273	Hydrolase Family 16
SC10_RS15670	COG2707	UPF0756 membrane protein
SC10_RS15675	COG0628	permease
SC10_RS15680	COG3030	protein affecting phage T7 exclusion by the F plasmid
SC10_RS15690	COG0205	6-phosphofructokinase activity
SC10_RS15695	COG0825	malonyl-CoA metabolic process
SC10_RS15700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SC10_RS15705	COG0281	malic enzyme
SC10_RS15710	COG0587	DNA-directed DNA polymerase activity
SC10_RS15730	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SC10_RS15740	COG4109	DRTGG domain
SC10_RS15745	COG1695	Transcriptional regulator
SC10_RS15750	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SC10_RS15755	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS15760	COG0165	Argininosuccinate lyase
SC10_RS15765	COG0137	argininosuccinate synthase activity
SC10_RS15770	COG0521	Mo-molybdopterin cofactor biosynthetic process
SC10_RS15775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
SC10_RS15780	COG0827	DNA restriction-modification system
SC10_RS15785	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SC10_RS15790	COG3874	Sporulation protein YtfJ
SC10_RS15800	COG1714	RDD family
SC10_RS15805	COG0616	signal peptide processing
SC10_RS15810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
SC10_RS15815	COG1846	Transcriptional regulator
SC10_RS15820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SC10_RS15830	COG0301	tRNA thio-modification
SC10_RS15835	COG1104	cysteine desulfurase activity
SC10_RS15840	COG1114	Component of the transport system for branched-chain amino acids
SC10_RS15845	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
SC10_RS15850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
SC10_RS15855	COG1309	transcriptional regulator
SC10_RS15860	COG1956	GAF domain-containing protein
SC10_RS15865	COG2203	Gaf domain
SC10_RS15865	COG2199	diguanylate cyclase activity
SC10_RS15870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
SC10_RS15880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
SC10_RS15885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
SC10_RS15890	COG0454	-acetyltransferase
SC10_RS15895	COG0517	IMP dehydrogenase activity
SC10_RS15900	COG0123	including yeast histone deacetylase and acetoin utilization protein
SC10_RS15905	COG1360	Flagellar Motor Protein
SC10_RS15910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
SC10_RS15915	COG1609	Transcriptional regulator
SC10_RS15920	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
SC10_RS15920	COG1605	Chorismate mutase
SC10_RS15930	COG3118	belongs to the thioredoxin family
SC10_RS15935	COG4980	gas vesicle protein
SC10_RS15940	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
SC10_RS15945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
SC10_RS15950	COG1674	ftsk spoiiie
SC10_RS15955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SC10_RS15960	COG4848	Belongs to the UPF0354 family
SC10_RS15965	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS15975	COG1363	Peptidase, m42
SC10_RS15980	COG5584	Small secreted protein
SC10_RS15985	COG0281	malic enzyme
SC10_RS15990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
SC10_RS15995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
SC10_RS16005	COG0510	thiamine kinase activity
SC10_RS16010	COG1523	belongs to the glycosyl hydrolase 13 family
SC10_RS16015	COG1597	lipid kinase activity
SC10_RS16025	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
SC10_RS16030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
SC10_RS16045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SC10_RS16050	COG2252	PERMEase
SC10_RS16055	COG4473	ABC transporter
SC10_RS16060	COG1131	(ABC) transporter
SC10_RS16065	COG1349	DNA-binding transcription factor activity
SC10_RS16070	COG1187	pseudouridine synthase activity
SC10_RS16075	COG2244	polysaccharide biosynthetic process
SC10_RS16080	COG2081	HI0933 family
SC10_RS16085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
SC10_RS16095	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SC10_RS16110	COG5578	integral membrane protein
SC10_RS16115	COG0673	inositol 2-dehydrogenase activity
SC10_RS16120	COG1653	transport
SC10_RS16125	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SC10_RS16130	COG4209	transmembrane transport
SC10_RS16135	COG2207	Transcriptional regulator
SC10_RS16140	COG1653	transport
SC10_RS16145	COG0395	ABC-type sugar transport system, permease component
SC10_RS16150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SC10_RS16155	COG1073	alpha beta
SC10_RS16165	COG0583	DNA-binding transcription factor activity
SC10_RS16170	COG0346	lactoylglutathione lyase activity
SC10_RS16175	COG0495	leucyl-tRNA aminoacylation
SC10_RS16185	COG2814	Major facilitator Superfamily
SC10_RS16190	COG1464	Belongs to the NlpA lipoprotein family
SC10_RS16195	COG2433	Pfam Transposase IS66
SC10_RS16200	COG0577	efflux transmembrane transporter activity
SC10_RS16205	COG1136	(ABC) transporter
SC10_RS16215	COG1131	(ABC) transporter
SC10_RS16220	COG1725	Transcriptional regulator
SC10_RS16230	COG1242	4 iron, 4 sulfur cluster binding
SC10_RS16235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SC10_RS16240	COG1301	dicarboxylic acid transport
SC10_RS16250	COG2267	carboxylic ester hydrolase activity
SC10_RS16255	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
SC10_RS16260	COG0671	phosphoesterase, PA-phosphatase related
SC10_RS16265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SC10_RS16265	COG0438	transferase activity, transferring glycosyl groups
SC10_RS16270	COG0367	asparagine synthase
SC10_RS16275	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
SC10_RS16280	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
SC10_RS16295	COG1506	peptidase
SC10_RS16300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SC10_RS16305	COG1116	anion transmembrane transporter activity
SC10_RS16310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SC10_RS16315	COG0494	nUDIX hydrolase
SC10_RS16325	COG4824	toxin secretion phage lysis holin
SC10_RS16330	COG0783	Belongs to the Dps family
SC10_RS16340	COG1854	S-ribosylhomocysteine lyase activity
SC10_RS16345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
SC10_RS16350	COG0288	reversible hydration of carbon dioxide
SC10_RS16360	COG0803	Belongs to the bacterial solute-binding protein 9 family
SC10_RS16365	COG0254	rRNA binding
SC10_RS16370	COG1271	oxidase subunit
SC10_RS16375	COG1294	oxidase, subunit
SC10_RS16390	COG4948	Mandelate Racemase Muconate Lactonizing
SC10_RS16395	COG0318	PFAM AMP-dependent synthetase and ligase
SC10_RS16400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
SC10_RS16405	COG0596	Alpha beta hydrolase
SC10_RS16410	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
SC10_RS16415	COG1169	isochorismate synthase
SC10_RS16420	COG1575	Belongs to the MenA family. Type 1 subfamily
SC10_RS16425	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
SC10_RS16430	COG0058	SHG alpha-glucan phosphorylase activity
SC10_RS16435	COG0297	glycogen (starch) synthase activity
SC10_RS16440	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SC10_RS16445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SC10_RS16450	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SC10_RS16570	COG1609	Transcriptional regulator
SC10_RS16575	COG3859	Proton-coupled thiamine transporter YuaJ
SC10_RS16580	COG3764	Sortase (surface protein transpeptidase)
SC10_RS16595	COG0457	Tetratricopeptide repeat
SC10_RS16600	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SC10_RS16605	COG0569	domain protein
SC10_RS16610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SC10_RS16620	COG2318	DinB family
SC10_RS16630	COG1454	alcohol dehydrogenase
SC10_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS16640	COG1510	regulation of RNA biosynthetic process
SC10_RS16650	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
SC10_RS16655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
SC10_RS16660	COG2140	Oxalate decarboxylase
SC10_RS16670	COG1397	ADP-ribosylglycohydrolase
SC10_RS16725	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
SC10_RS16735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SC10_RS16740	COG0726	polysaccharide deacetylase
SC10_RS16745	COG1408	metallophosphoesterase
SC10_RS16750	COG1968	undecaprenyl-diphosphatase activity
SC10_RS16755	COG0628	permease
SC10_RS16760	COG0673	inositol 2-dehydrogenase activity
SC10_RS16765	COG0693	protein deglycase activity
SC10_RS16770	COG0840	transmembrane signaling receptor activity
SC10_RS16775	COG0840	transmembrane signaling receptor activity
SC10_RS16780	COG0840	transmembrane signaling receptor activity
SC10_RS16790	COG2070	2-Nitropropane dioxygenase
SC10_RS16795	COG0432	Pfam Uncharacterised protein family UPF0047
SC10_RS16800	COG0366	Alpha amylase catalytic
SC10_RS16815	COG5297	Belongs to the glycosyl hydrolase family 6
SC10_RS16820	COG1253	flavin adenine dinucleotide binding
SC10_RS16825	COG2738	Putative neutral zinc metallopeptidase
SC10_RS16840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SC10_RS16850	COG2323	membrane
SC10_RS16855	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
SC10_RS16865	COG0166	Belongs to the GPI family
SC10_RS16870	COG1979	alcohol dehydrogenase
SC10_RS16875	COG2155	Conserved Protein
SC10_RS16880	COG1098	S1 RNA binding domain
SC10_RS16885	COG0436	Aminotransferase
SC10_RS16890	COG1522	sequence-specific DNA binding
SC10_RS16895	COG2267	carboxylic ester hydrolase activity
SC10_RS16910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SC10_RS16925	COG5018	Exonuclease
SC10_RS16930	COG2814	Major facilitator Superfamily
SC10_RS16935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SC10_RS16940	COG3011	Protein conserved in bacteria
SC10_RS16950	COG3290	protein histidine kinase activity
SC10_RS16955	COG4565	transcriptional regulatory protein
SC10_RS16960	COG1183	phosphatidylcholine synthase activity
SC10_RS16965	COG0586	Pfam SNARE associated Golgi protein
SC10_RS16970	COG0688	phosphatidylethanolamine metabolic process
SC10_RS16975	COG3493	citrate carrier protein
SC10_RS16985	COG2111	Na H antiporter
SC10_RS16985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
SC10_RS16990	COG2111	Na H antiporter
SC10_RS16995	COG1006	Multisubunit Na H antiporter MnhC subunit
SC10_RS17000	COG0651	ATP synthesis coupled electron transport
SC10_RS17005	COG1863	multisubunit Na H antiporter MnhE subunit
SC10_RS17010	COG2212	antiporter activity
SC10_RS17015	COG1320	monovalent cation:proton antiporter activity
SC10_RS17020	COG2050	protein possibly involved in aromatic compounds catabolism
SC10_RS17025	COG2197	response regulator
SC10_RS17030	COG4585	Histidine kinase
SC10_RS17055	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
SC10_RS17060	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SC10_RS17065	COG1335	isochorismatase
SC10_RS17070	COG5506	Protein of unknown function (DUF1694)
SC10_RS17085	COG0628	permease
SC10_RS17090	COG1959	2 iron, 2 sulfur cluster binding
SC10_RS17095	COG0657	acetylesterase activity
SC10_RS17105	COG1418	mRNA catabolic process
SC10_RS17110	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS17125	COG1511	domain protein
SC10_RS17130	COG0433	COG0433 Predicted ATPase
SC10_RS17130	COG1674	ftsk spoiiie
SC10_RS17135	COG4499	WXG100 protein secretion system (Wss), protein YukC
SC10_RS17140	COG5417	Belongs to the EsaB family
SC10_RS17145	COG4842	Belongs to the WXG100 family
SC10_RS17150	COG1115	amino acid carrier protein
SC10_RS17155	COG2508	Transcriptional regulator
SC10_RS17155	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
SC10_RS17160	COG0686	Belongs to the AlaDH PNT family
SC10_RS17170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
SC10_RS17175	COG1268	BioY protein
SC10_RS17180	COG2056	Na+-H+ antiporter family
SC10_RS17185	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
SC10_RS17190	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
SC10_RS17195	COG3584	3D domain protein
SC10_RS17210	COG1252	NADH dehydrogenase
SC10_RS17215	COG0492	ferredoxin-NADP+ reductase activity
SC10_RS17225	COG0454	-acetyltransferase
SC10_RS17230	COG0316	Belongs to the HesB IscA family
SC10_RS17235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
SC10_RS17240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SC10_RS17245	COG4844	belongs to the
SC10_RS17250	COG1252	NADH dehydrogenase
SC10_RS17255	COG2323	membrane
SC10_RS17260	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
SC10_RS17265	COG5646	InterPro IPR014922
SC10_RS17280	COG0457	Tetratricopeptide repeat
SC10_RS17285	COG3479	Phenolic acid decarboxylase
SC10_RS17295	COG4837	Protein of unknown function (DUF1462)
SC10_RS17300	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
SC10_RS17305	COG4946	Tricorn protease homolog
SC10_RS17305	COG0823	Involved in the tonB-independent uptake of proteins
SC10_RS17305	COG1506	peptidase
SC10_RS17310	COG0083	homoserine kinase activity
SC10_RS17315	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
SC10_RS17320	COG0460	homoserine dehydrogenase
SC10_RS17325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SC10_RS17330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
SC10_RS17335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
SC10_RS17340	COG0647	UMP catabolic process
SC10_RS17345	COG2445	Protein of unknown function DUF86
SC10_RS17350	COG4470	Protein conserved in bacteria
SC10_RS17365	COG0739	heme binding
SC10_RS17370	COG0733	neurotransmitter:sodium symporter activity
SC10_RS17380	COG3377	Domain of unknown function (DUF1805)
SC10_RS17385	COG0737	Belongs to the 5'-nucleotidase family
SC10_RS17390	COG0730	response to heat
SC10_RS17395	COG1801	Protein of unknown function DUF72
SC10_RS17405	COG3226	Transcriptional regulator
SC10_RS17410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
SC10_RS17415	COG2508	Transcriptional regulator
SC10_RS17420	COG2814	Major facilitator Superfamily
SC10_RS17425	COG1288	antiporter activity
SC10_RS17430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
SC10_RS17435	COG2356	endonuclease I
SC10_RS17445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SC10_RS17460	COG0457	Tetratricopeptide repeat
SC10_RS17470	COG0719	Fe-S assembly protein
SC10_RS17475	COG0822	iron-sulfur transferase activity
SC10_RS17480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SC10_RS17485	COG0719	Fe-S assembly protein
SC10_RS17490	COG0396	ATPase activity
SC10_RS17500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SC10_RS17505	COG1464	Belongs to the NlpA lipoprotein family
SC10_RS17510	COG2011	ABC-type metal ion transport system permease component
SC10_RS17515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SC10_RS17525	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SC10_RS17530	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SC10_RS17540	COG0509	glycine decarboxylation via glycine cleavage system
SC10_RS17545	COG1393	Belongs to the ArsC family
SC10_RS17550	COG1960	acyl-CoA dehydrogenase activity
SC10_RS17555	COG0183	Belongs to the thiolase family
SC10_RS17560	COG1024	Enoyl-CoA hydratase
SC10_RS17560	COG1250	3-hydroxyacyl-CoA dehydrogenase
SC10_RS17570	COG5577	PFAM Coat F domain
SC10_RS17585	COG1120	ATPase activity
SC10_RS17590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS17595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS17600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS17615	COG1686	Belongs to the peptidase S11 family
SC10_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS17625	COG0783	Belongs to the Dps family
SC10_RS17630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SC10_RS17635	COG0745	RESPONSE REGULATOR receiver
SC10_RS17640	COG2205	protein histidine kinase activity
SC10_RS17640	COG2770	Histidine kinase
SC10_RS17645	COG1309	transcriptional regulator
SC10_RS17650	COG0114	fumarate hydratase activity
SC10_RS17655	COG0697	spore germination
SC10_RS17660	COG0814	amino acid
SC10_RS17675	COG2197	response regulator
SC10_RS17680	COG4585	Histidine kinase
SC10_RS17685	COG4758	membrane
SC10_RS17690	COG3595	metallopeptidase activity
SC10_RS17695	COG1842	Phage shock protein A
SC10_RS17700	COG4758	membrane
SC10_RS17705	COG4677	pectinesterase activity
SC10_RS17710	COG2096	Adenosyltransferase
SC10_RS17715	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS17720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SC10_RS17735	COG1454	alcohol dehydrogenase
SC10_RS17740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SC10_RS17745	COG1120	ATPase activity
SC10_RS17750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS17755	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS17760	COG1802	Transcriptional regulator
SC10_RS17765	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS17770	COG2258	MOSC domain
SC10_RS17775	COG0583	DNA-binding transcription factor activity
SC10_RS17785	COG2721	sulfolactate sulfo-lyase activity
SC10_RS17790	COG0246	Mannitol dehydrogenase
SC10_RS17795	COG1609	Transcriptional regulator
SC10_RS17800	COG2211	Major facilitator Superfamily
SC10_RS17805	COG1904	glucuronate isomerase
SC10_RS17810	COG2205	protein histidine kinase activity
SC10_RS17815	COG0745	RESPONSE REGULATOR receiver
SC10_RS17820	COG1120	ATPase activity
SC10_RS17825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS17830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS17835	COG0531	amino acid
SC10_RS17845	COG1988	membrane-bound metal-dependent
SC10_RS17850	COG1368	sulfuric ester hydrolase activity
SC10_RS17855	COG2814	Major facilitator Superfamily
SC10_RS17860	COG0656	L-ascorbic acid biosynthetic process
SC10_RS17865	COG1940	carbohydrate kinase activity
SC10_RS17870	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SC10_RS17880	COG0596	Alpha beta hydrolase
SC10_RS17885	COG3973	AAA domain
SC10_RS17890	COG2860	membrane
SC10_RS17895	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
SC10_RS17895	COG0456	acetyltransferase
SC10_RS17900	COG0456	acetyltransferase
SC10_RS17905	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
SC10_RS17910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
SC10_RS17915	COG2217	Heavy metal translocating P-type atpase
SC10_RS17920	COG1653	transport
SC10_RS17925	COG1175	transmembrane transport
SC10_RS17930	COG0395	ABC-type sugar transport system, permease component
SC10_RS17935	COG1501	Belongs to the glycosyl hydrolase 31 family
SC10_RS17940	COG1472	Belongs to the glycosyl hydrolase 3 family
SC10_RS17945	COG1121	(ABC) transporter
SC10_RS17950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SC10_RS17955	COG0803	Belongs to the bacterial solute-binding protein 9 family
SC10_RS17975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS17975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS17975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SC10_RS17980	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS17990	COG2217	Heavy metal translocating P-type atpase
SC10_RS17995	COG2608	mercury ion transmembrane transporter activity
SC10_RS18000	COG1937	Protein conserved in bacteria
SC10_RS18005	COG0693	protein deglycase activity
SC10_RS18010	COG1349	DNA-binding transcription factor activity
SC10_RS18015	COG1070	Carbohydrate kinase
SC10_RS18020	COG4952	isomerase
SC10_RS18030	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS18030	COG3347	Dehydrogenase
SC10_RS18040	COG2814	Major facilitator Superfamily
SC10_RS18045	COG2814	Major facilitator Superfamily
SC10_RS18055	COG2124	cytochrome p450
SC10_RS18065	COG1846	Transcriptional regulator
SC10_RS18075	COG0673	inositol 2-dehydrogenase activity
SC10_RS18080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
SC10_RS18085	COG1054	Belongs to the UPF0176 family
SC10_RS18095	COG1191	sigma factor activity
SC10_RS18100	COG2140	Oxalate decarboxylase
SC10_RS18120	COG5520	Belongs to the glycosyl hydrolase 30 family
SC10_RS18125	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS18140	COG5444	nuclease activity
SC10_RS18150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
SC10_RS18155	COG0557	exoribonuclease II activity
SC10_RS18160	COG1647	Serine aminopeptidase, S33
SC10_RS18165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
SC10_RS18170	COG2002	toxin-antitoxin pair type II binding
SC10_RS18175	COG1476	TRANSCRIPTIONal
SC10_RS18180	COG1396	sequence-specific DNA binding
SC10_RS18185	COG1396	sequence-specific DNA binding
SC10_RS18190	COG1174	glycine betaine transport
SC10_RS18195	COG1732	Glycine betaine
SC10_RS18200	COG1174	glycine betaine transport
SC10_RS18205	COG0517	IMP dehydrogenase activity
SC10_RS18205	COG1125	glycine betaine transport
SC10_RS18210	COG1510	regulation of RNA biosynthetic process
SC10_RS18215	COG2095	MarC family integral membrane protein
SC10_RS18220	COG3064	Membrane
SC10_RS18225	COG4640	response to antibiotic
SC10_RS18245	COG0693	protein deglycase activity
SC10_RS18250	COG0148	phosphopyruvate hydratase activity
SC10_RS18255	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
SC10_RS18260	COG0149	triose-phosphate isomerase activity
SC10_RS18265	COG0126	phosphoglycerate kinase activity
SC10_RS18270	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
SC10_RS18275	COG2390	Transcriptional regulator
SC10_RS18280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SC10_RS18285	COG1113	amino acid transport
SC10_RS18305	COG1556	Lactate utilization protein
SC10_RS18310	COG1139	Iron-sulfur cluster binding protein
SC10_RS18315	COG0247	lactate metabolic process
SC10_RS18320	COG2186	Transcriptional regulator
SC10_RS18325	COG1620	l-lactate permease
SC10_RS18330	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
SC10_RS18340	COG5039	Polysaccharide pyruvyl transferase
SC10_RS18345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SC10_RS18350	COG0110	maltose O-acetyltransferase activity
SC10_RS18355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SC10_RS18360	COG2244	polysaccharide biosynthetic process
SC10_RS18365	COG1216	Glycosyl transferase, family 2
SC10_RS18370	COG5039	Polysaccharide pyruvyl transferase
SC10_RS18375	COG1216	Glycosyl transferase, family 2
SC10_RS18385	COG0438	transferase activity, transferring glycosyl groups
SC10_RS18390	COG1215	transferase activity, transferring glycosyl groups
SC10_RS18395	COG0438	transferase activity, transferring glycosyl groups
SC10_RS18400	COG1086	Polysaccharide biosynthesis protein
SC10_RS18405	COG0489	protein tyrosine kinase activity
SC10_RS18410	COG3944	biosynthesis protein
SC10_RS18415	COG1396	sequence-specific DNA binding
SC10_RS18420	COG2249	NAD(P)H dehydrogenase (quinone) activity
SC10_RS18425	COG2271	Major facilitator Superfamily
SC10_RS18435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
SC10_RS18445	COG1454	alcohol dehydrogenase
SC10_RS18450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SC10_RS18460	COG1733	regulation of RNA biosynthetic process
SC10_RS18465	COG1902	pentaerythritol trinitrate reductase activity
SC10_RS18470	COG1621	beta-fructofuranosidase activity
SC10_RS18475	COG1621	beta-fructofuranosidase activity
SC10_RS18485	COG0740	serine-type endopeptidase activity
SC10_RS18490	COG1611	Belongs to the LOG family
SC10_RS18495	COG1694	Mazg nucleotide pyrophosphohydrolase
SC10_RS18500	COG1078	dGTPase activity
SC10_RS18505	COG0659	secondary active sulfate transmembrane transporter activity
SC10_RS18510	COG0288	reversible hydration of carbon dioxide
SC10_RS18515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SC10_RS18520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
SC10_RS18525	COG0640	Transcriptional regulator
SC10_RS18535	COG2732	(Barnase) inhibitor
SC10_RS18540	COG2162	N-hydroxyarylamine O-acetyltransferase activity
SC10_RS18545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS18550	COG1481	regulation of sporulation
SC10_RS18555	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SC10_RS18560	COG1660	Displays ATPase and GTPase activities
SC10_RS18565	COG1051	belongs to the nudix hydrolase family
SC10_RS18570	COG0492	ferredoxin-NADP+ reductase activity
SC10_RS18575	COG0457	Tetratricopeptide repeat
SC10_RS18580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SC10_RS18585	COG0140	phosphoribosyl-ATP diphosphatase activity
SC10_RS18585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
SC10_RS18590	COG0107	imidazoleglycerol-phosphate synthase activity
SC10_RS18595	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
SC10_RS18600	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
SC10_RS18605	COG0131	Imidazoleglycerol-phosphate dehydratase
SC10_RS18610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
SC10_RS18615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
SC10_RS18620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
SC10_RS18625	COG4990	cell redox homeostasis
SC10_RS18630	COG5297	Belongs to the glycosyl hydrolase family 6
SC10_RS18635	COG0110	maltose O-acetyltransferase activity
SC10_RS18640	COG0546	phosphoglycolate phosphatase activity
SC10_RS18645	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
SC10_RS18650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
SC10_RS18655	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
SC10_RS18660	COG1846	Transcriptional regulator
SC10_RS18665	COG2814	Major facilitator Superfamily
SC10_RS18670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
SC10_RS18675	COG1950	PFAM Membrane protein of
SC10_RS18680	COG1983	PspC domain protein
SC10_RS18685	COG3595	metallopeptidase activity
SC10_RS18705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SC10_RS18710	COG0556	nucleotide-excision repair
SC10_RS18715	COG4897	Protein conserved in bacteria
SC10_RS18725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SC10_RS18735	COG0793	Belongs to the peptidase S41A family
SC10_RS18735	COG3409	Peptidoglycan-binding domain 1 protein
SC10_RS18740	COG0473	3-isopropylmalate dehydrogenase activity
SC10_RS18745	COG0791	NLP P60 protein
SC10_RS18745	COG3883	PFAM NLP P60 protein
SC10_RS18750	COG2177	Part of the ABC transporter FtsEX involved in
SC10_RS18755	COG2884	Cell division ATP-binding protein ftsE
SC10_RS18760	COG2010	Cytochrome c
SC10_RS18765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS18770	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SC10_RS18775	COG0653	protein targeting
SC10_RS18780	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
SC10_RS18795	COG1516	flagellar protein fliS
SC10_RS18800	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
SC10_RS18805	COG1334	flagellar protein FlaG
SC10_RS18815	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SC10_RS18820	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
SC10_RS18825	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
SC10_RS18835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
SC10_RS18840	COG4786	Flagellar basal body rod
SC10_RS18840	COG1256	bacterial-type flagellum assembly
SC10_RS18845	COG3418	PFAM FlgN family protein
SC10_RS18850	COG2747	anti-sigma28 factor FlgM
SC10_RS18860	COG1040	competence protein
SC10_RS18870	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SC10_RS18875	COG1307	EDD domain protein, DegV family
SC10_RS18880	COG2197	response regulator
SC10_RS18885	COG4585	Histidine kinase
SC10_RS18890	COG1739	Uncharacterized protein family UPF0029
SC10_RS18895	COG1316	TRANSCRIPTIONal
SC10_RS18905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
SC10_RS18910	COG0438	transferase activity, transferring glycosyl groups
SC10_RS18915	COG1215	transferase activity, transferring glycosyl groups
SC10_RS18920	COG3206	protein involved in exopolysaccharide biosynthesis
SC10_RS18925	COG3307	-O-antigen
SC10_RS18930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
SC10_RS18935	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
SC10_RS18940	COG0297	glycogen (starch) synthase activity
SC10_RS18940	COG0438	transferase activity, transferring glycosyl groups
SC10_RS18945	COG2244	polysaccharide biosynthetic process
SC10_RS18955	COG2247	cell wall binding repeat
SC10_RS18955	COG0860	N-Acetylmuramoyl-L-alanine amidase
SC10_RS18970	COG1316	TRANSCRIPTIONal
SC10_RS18975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SC10_RS18980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SC10_RS18985	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SC10_RS18990	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
SC10_RS18995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
SC10_RS19000	COG0438	transferase activity, transferring glycosyl groups
SC10_RS19005	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SC10_RS19010	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SC10_RS19010	COG0463	Glycosyl transferase, family 2
SC10_RS19015	COG1682	transport, permease protein
SC10_RS19020	COG1134	teichoic acid transport
SC10_RS19025	COG4193	domain, Protein
SC10_RS19045	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SC10_RS19050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
SC10_RS19055	COG0438	transferase activity, transferring glycosyl groups
SC10_RS19065	COG4193	domain, Protein
SC10_RS19070	COG1482	cell wall glycoprotein biosynthetic process
SC10_RS19090	COG0800	Aldolase
SC10_RS19095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SC10_RS19100	COG1609	Transcriptional regulator
SC10_RS19105	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
SC10_RS19110	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS19115	COG1063	alcohol dehydrogenase
SC10_RS19120	COG2814	Major facilitator Superfamily
SC10_RS19125	COG1316	TRANSCRIPTIONal
SC10_RS19130	COG0561	phosphatase activity
SC10_RS19135	COG0791	NLP P60 protein
SC10_RS19140	COG2843	Capsule synthesis protein
SC10_RS19150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
SC10_RS19155	COG1609	Transcriptional regulator
SC10_RS19160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SC10_RS19165	COG1869	D-ribose catabolic process
SC10_RS19170	COG1129	ABC transporter
SC10_RS19175	COG1172	Belongs to the binding-protein-dependent transport system permease family
SC10_RS19180	COG1879	ABC-type sugar transport system periplasmic component
SC10_RS19185	COG0583	DNA-binding transcription factor activity
SC10_RS19190	COG2226	methyltransferase
SC10_RS19195	COG3527	Alpha-acetolactate decarboxylase
SC10_RS19200	COG0028	Belongs to the TPP enzyme family
SC10_RS19205	COG0583	DNA-binding transcription factor activity
SC10_RS19210	COG0405	Gamma-glutamyltransferase
SC10_RS19215	COG1522	sequence-specific DNA binding
SC10_RS19220	COG2059	Chromate
SC10_RS19225	COG2059	Chromate
SC10_RS19230	COG4464	protein tyrosine phosphatase activity
SC10_RS19235	COG3944	biosynthesis protein
SC10_RS19240	COG4715	Zinc finger, swim domain protein
SC10_RS19245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SC10_RS19250	COG3878	Protein conserved in bacteria
SC10_RS19255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SC10_RS19270	COG0561	phosphatase activity
SC10_RS19275	COG1349	DNA-binding transcription factor activity
SC10_RS19285	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS19295	COG3732	PTS system glucitol sorbitol-specific
SC10_RS19315	COG0629	single-stranded DNA binding
SC10_RS19330	COG1970	mechanosensitive ion channel activity
SC10_RS19335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
SC10_RS19340	COG4786	Flagellar basal body rod
SC10_RS19345	COG4786	Flagellar basal body rod
SC10_RS19350	COG1077	Cell shape determining protein MreB Mrl
SC10_RS19355	COG1609	Transcriptional regulator
SC10_RS19360	COG1846	Transcriptional regulator
SC10_RS19365	COG2814	Major facilitator Superfamily
SC10_RS19370	COG0671	phosphoesterase, PA-phosphatase related
SC10_RS19375	COG1227	inorganic diphosphatase activity
SC10_RS19380	COG3546	catalase activity
SC10_RS19385	COG3361	conserved protein (COG2071)
SC10_RS19400	COG0517	IMP dehydrogenase activity
SC10_RS19405	COG0598	Magnesium transport protein CorA
SC10_RS19410	COG1253	flavin adenine dinucleotide binding
SC10_RS19415	COG0004	ammonium transporteR
SC10_RS19420	COG0347	Belongs to the P(II) protein family
SC10_RS19425	COG0740	serine-type endopeptidase activity
SC10_RS19435	COG0739	heme binding
SC10_RS19440	COG1247	-acetyltransferase
SC10_RS19450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SC10_RS19455	COG0477	Major facilitator Superfamily
SC10_RS19460	COG3251	PFAM MbtH domain protein
SC10_RS19465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS19470	COG3433	isochorismatase activity
SC10_RS19470	COG1535	isochorismatase
SC10_RS19475	COG1021	2,3-dihydroxybenzoate-AMP ligase
SC10_RS19480	COG1169	isochorismate synthase
SC10_RS19485	COG1028	Short-chain dehydrogenase reductase Sdr
SC10_RS19490	COG2819	hydrolase of the alpha beta superfamily
SC10_RS19495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS19500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS19505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS19510	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS19510	COG2207	Transcriptional regulator
SC10_RS19520	COG2910	NAD(P)H-binding
SC10_RS19525	COG1959	2 iron, 2 sulfur cluster binding
SC10_RS19535	COG1994	Peptidase M50
SC10_RS19540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
SC10_RS19545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
SC10_RS19550	COG2223	nitrite transmembrane transporter activity
SC10_RS19555	COG3383	formate dehydrogenase (NAD+) activity
SC10_RS19560	COG2304	oxidoreductase activity
SC10_RS19565	COG2304	oxidoreductase activity
SC10_RS19570	COG2385	sporulation resulting in formation of a cellular spore
SC10_RS19575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SC10_RS19585	COG4836	Membrane
SC10_RS19590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
SC10_RS19595	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
SC10_RS19600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
SC10_RS19605	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
SC10_RS19610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SC10_RS19615	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
SC10_RS19625	COG0356	it plays a direct role in the translocation of protons across the membrane
SC10_RS19640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SC10_RS19645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
SC10_RS19650	COG4475	Protein of unknown function (DUF436)
SC10_RS19655	COG0698	ribose 5-phosphate isomerase
SC10_RS19660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SC10_RS19665	COG1971	Probably functions as a manganese efflux pump
SC10_RS19670	COG0009	L-threonylcarbamoyladenylate synthase
SC10_RS19675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
SC10_RS19685	COG0738	Major facilitator superfamily
SC10_RS19690	COG0673	inositol 2-dehydrogenase activity
SC10_RS19695	COG0561	phosphatase activity
SC10_RS19700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SC10_RS19705	COG1609	Transcriptional regulator
SC10_RS19715	COG2890	protein-(glutamine-N5) methyltransferase activity
SC10_RS19720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
SC10_RS19725	COG0346	lactoylglutathione lyase activity
SC10_RS19730	COG0789	Transcriptional regulator
SC10_RS19735	COG0679	Auxin Efflux Carrier
SC10_RS19740	COG0281	malic enzyme
SC10_RS19745	COG1435	thymidine kinase activity
SC10_RS19750	COG0254	rRNA binding
SC10_RS19755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
SC10_RS19760	COG1494	fructose-1,6-bisphosphatase
SC10_RS19765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SC10_RS19770	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
SC10_RS19775	COG0191	fructose-bisphosphate aldolase activity
SC10_RS19780	COG2204	response regulator
SC10_RS19785	COG4821	SIS domain
SC10_RS19790	COG0504	CTP synthase activity
SC10_RS19795	COG3343	RNA polymerase activity
SC10_RS19800	COG1960	acyl-CoA dehydrogenase activity
SC10_RS19805	COG1960	acyl-CoA dehydrogenase activity
SC10_RS19810	COG1250	3-hydroxyacyl-CoA dehydrogenase
SC10_RS19815	COG0183	Belongs to the thiolase family
SC10_RS19820	COG2181	nitrate reductase activity
SC10_RS19820	COG0247	lactate metabolic process
SC10_RS19825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SC10_RS19835	COG0018	arginyl-trna synthetase
SC10_RS19840	COG4506	Protein conserved in bacteria
SC10_RS19845	COG0010	Belongs to the arginase family
SC10_RS19850	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SC10_RS19855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SC10_RS19865	COG1994	Peptidase M50
SC10_RS19870	COG1942	4-Oxalocrotonate Tautomerase
SC10_RS19880	COG3465	dGTPase activity
SC10_RS19885	COG1078	dGTPase activity
SC10_RS19890	COG4844	belongs to the
SC10_RS19915	COG2814	Major facilitator Superfamily
SC10_RS19940	COG1414	Transcriptional regulator
SC10_RS19950	COG0280	phosphate acetyltransferase
SC10_RS19955	COG3253	May function as heme-dependent peroxidase
SC10_RS19965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SC10_RS19985	COG1131	(ABC) transporter
SC10_RS20000	COG2363	Small membrane protein
SC10_RS20005	COG2233	PERMEase
SC10_RS20015	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS20020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
SC10_RS20025	COG1216	Glycosyl transferase, family 2
SC10_RS20030	COG0351	phosphomethylpyrimidine kinase
SC10_RS20040	COG1621	beta-fructofuranosidase activity
SC10_RS20045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS20045	COG1263	PTS System
SC10_RS20050	COG3711	transcriptional antiterminator
SC10_RS20060	COG1404	Belongs to the peptidase S8 family
SC10_RS20070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
SC10_RS20075	COG0778	Nitroreductase
SC10_RS20080	COG1473	amidohydrolase
SC10_RS20085	COG0772	Belongs to the SEDS family
SC10_RS20090	COG0772	Belongs to the SEDS family
SC10_RS20095	COG3314	Sporulation integral membrane protein YlbJ
SC10_RS20110	COG0456	acetyltransferase
SC10_RS20145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
SC10_RS20155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
SC10_RS20160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
SC10_RS20165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SC10_RS20180	COG0655	NAD(P)H dehydrogenase (quinone) activity
SC10_RS20185	COG3162	membrane
SC10_RS20190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS20195	COG1070	Carbohydrate kinase
SC10_RS20200	COG2115	Belongs to the xylose isomerase family
SC10_RS20205	COG1940	carbohydrate kinase activity
SC10_RS20210	COG0352	thiamine-phosphate diphosphorylase activity
SC10_RS20215	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
SC10_RS20220	COG0583	DNA-binding transcription factor activity
SC10_RS20235	COG1380	Effector of murein hydrolase LrgA
SC10_RS20240	COG1346	cytolysis
SC10_RS20250	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SC10_RS20255	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SC10_RS20260	COG0346	lactoylglutathione lyase activity
SC10_RS20265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
SC10_RS20270	COG1442	glycosyl transferase family 8
SC10_RS20280	COG4585	Histidine kinase
SC10_RS20285	COG2197	response regulator
SC10_RS20290	COG2409	Drug exporters of the RND superfamily
SC10_RS20295	COG5522	Integral membrane protein (intg_mem_TP0381)
SC10_RS20300	COG2271	Major facilitator Superfamily
SC10_RS20305	COG4948	Mandelate Racemase Muconate Lactonizing
SC10_RS20310	COG0800	Aldolase
SC10_RS20315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SC10_RS20325	COG2234	aminopeptidase activity
SC10_RS20330	COG0477	Major facilitator Superfamily
SC10_RS20345	COG2357	RelA SpoT domain protein
SC10_RS20360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
SC10_RS20365	COG1696	Membrane protein involved in D-alanine export
SC10_RS20370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SC10_RS20375	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SC10_RS20380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SC10_RS20385	COG2814	Major facilitator Superfamily
SC10_RS20390	COG1486	melibiose metabolic process
SC10_RS20395	COG1447	Phosphotransferase system cellobiose-specific component IIA
SC10_RS20400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS20405	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS20410	COG3711	transcriptional antiterminator
SC10_RS20410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SC10_RS20415	COG2094	Belongs to the DNA glycosylase MPG family
SC10_RS20425	COG0372	Belongs to the citrate synthase family
SC10_RS20430	COG2079	MmgE PrpD family protein
SC10_RS20435	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
SC10_RS20450	COG1132	(ABC) transporter
SC10_RS20455	COG2755	lipolytic protein G-D-S-L family
SC10_RS20470	COG2814	Major facilitator Superfamily
SC10_RS20475	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
SC10_RS20480	COG1131	(ABC) transporter
SC10_RS20500	COG1595	DNA-templated transcription, initiation
SC10_RS20505	COG2814	Major facilitator Superfamily
SC10_RS20515	COG0753	catalase activity
SC10_RS20520	COG0753	catalase activity
SC10_RS20525	COG0735	belongs to the Fur family
SC10_RS20530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
SC10_RS20540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SC10_RS20545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
SC10_RS20550	COG4988	ABC transporter
SC10_RS20555	COG1294	oxidase, subunit
SC10_RS20560	COG1271	oxidase subunit
SC10_RS20570	COG2116	formate transmembrane transporter activity
SC10_RS20580	COG0281	malic enzyme
SC10_RS20585	COG1757	Na H antiporter
SC10_RS20590	COG1027	Aspartate ammonia-lyase
SC10_RS20595	COG0252	asparaginase activity
SC10_RS20600	COG1396	sequence-specific DNA binding
SC10_RS20605	COG2706	6-phosphogluconolactonase activity
SC10_RS20610	COG0745	RESPONSE REGULATOR receiver
SC10_RS20615	COG2205	protein histidine kinase activity
SC10_RS20620	COG1136	(ABC) transporter
SC10_RS20625	COG0577	efflux transmembrane transporter activity
SC10_RS20630	COG5294	Protein conserved in bacteria
SC10_RS20645	COG0726	polysaccharide deacetylase
SC10_RS20650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SC10_RS20660	COG1215	transferase activity, transferring glycosyl groups
SC10_RS20665	COG3493	citrate carrier protein
SC10_RS20670	COG0584	glycerophosphoryl diester phosphodiesterase
SC10_RS20685	COG1368	sulfuric ester hydrolase activity
SC10_RS20695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SC10_RS20705	COG2235	arginine
SC10_RS20710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
SC10_RS20720	COG0549	Belongs to the carbamate kinase family
SC10_RS20730	COG2723	6-phospho-beta-galactosidase activity
SC10_RS20735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SC10_RS20745	COG2195	Cleaves the N-terminal amino acid of tripeptides
SC10_RS20755	COG2223	nitrite transmembrane transporter activity
SC10_RS20760	COG0395	ABC-type sugar transport system, permease component
SC10_RS20765	COG1175	transmembrane transport
SC10_RS20775	COG1609	Transcriptional regulator
SC10_RS20790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SC10_RS20795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SC10_RS20800	COG0463	Glycosyl transferase, family 2
SC10_RS20805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SC10_RS20835	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SC10_RS20845	COG0693	protein deglycase activity
SC10_RS20845	COG0753	catalase activity
SC10_RS20855	COG2723	6-phospho-beta-galactosidase activity
SC10_RS20860	COG2190	(PTS) system
SC10_RS20860	COG1263	PTS System
SC10_RS20860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS20865	COG3711	transcriptional antiterminator
SC10_RS20870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SC10_RS20875	COG1122	ATPase activity
SC10_RS20880	COG4721	ABC-type cobalt transport system, permease component
SC10_RS20885	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SC10_RS20890	COG2224	Isocitrate lyase
SC10_RS20895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
SC10_RS20900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
SC10_RS20905	COG0577	efflux transmembrane transporter activity
SC10_RS20910	COG1136	(ABC) transporter
SC10_RS20915	COG2205	protein histidine kinase activity
SC10_RS20920	COG0745	RESPONSE REGULATOR receiver
SC10_RS20925	COG2723	6-phospho-beta-galactosidase activity
SC10_RS20930	COG1263	PTS System
SC10_RS20930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS20930	COG2190	(PTS) system
SC10_RS20940	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
SC10_RS20945	COG3507	Belongs to the glycosyl hydrolase 43 family
SC10_RS20950	COG0513	Belongs to the DEAD box helicase family
SC10_RS20985	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SC10_RS20990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
SC10_RS20995	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
SC10_RS21000	COG2390	Transcriptional regulator
SC10_RS21010	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
SC10_RS21015	COG3706	GGDEF domain
SC10_RS21020	COG5298	Protein conserved in bacteria
SC10_RS21025	COG1215	transferase activity, transferring glycosyl groups
SC10_RS21035	COG3977	Valine--pyruvate aminotransferase
SC10_RS21050	COG1181	Belongs to the D-alanine--D-alanine ligase family
SC10_RS21060	COG0191	fructose-bisphosphate aldolase activity
SC10_RS21065	COG1082	Xylose isomerase domain protein TIM barrel
SC10_RS21070	COG1082	Xylose isomerase domain protein TIM barrel
SC10_RS21075	COG0673	inositol 2-dehydrogenase activity
SC10_RS21080	COG2814	Major facilitator Superfamily
SC10_RS21085	COG1082	Xylose isomerase domain protein TIM barrel
SC10_RS21090	COG3962	Belongs to the TPP enzyme family
SC10_RS21095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
SC10_RS21100	COG3718	enzyme involved in inositol metabolism
SC10_RS21105	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS21110	COG1349	DNA-binding transcription factor activity
SC10_RS21115	COG0667	Aldo Keto reductase
SC10_RS21120	COG0584	glycerophosphoryl diester phosphodiesterase
SC10_RS21125	COG2271	Major facilitator Superfamily
SC10_RS21130	COG0326	Molecular chaperone. Has ATPase activity
SC10_RS21135	COG0488	(ABC) transporter
SC10_RS21140	COG0561	phosphatase activity
SC10_RS21160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS21190	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
SC10_RS21195	COG0577	efflux transmembrane transporter activity
SC10_RS21200	COG1136	(ABC) transporter
SC10_RS21205	COG2205	protein histidine kinase activity
SC10_RS21210	COG0745	RESPONSE REGULATOR receiver
SC10_RS21220	COG0840	transmembrane signaling receptor activity
SC10_RS21220	COG5278	phosphoserine phosphatase activity
SC10_RS21225	COG1115	amino acid carrier protein
SC10_RS21230	COG0686	Belongs to the AlaDH PNT family
SC10_RS21235	COG3867	Arabinogalactan endo-beta-1,4-galactanase
SC10_RS21240	COG1874	Beta-galactosidase
SC10_RS21245	COG3833	ABC-type maltose transport systems, permease component
SC10_RS21250	COG1175	transmembrane transport
SC10_RS21255	COG2182	Extracellular solute-binding protein
SC10_RS21260	COG1609	Transcriptional regulator
SC10_RS21265	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SC10_RS21270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SC10_RS21275	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SC10_RS21280	COG1940	carbohydrate kinase activity
SC10_RS21290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SC10_RS21320	COG1454	alcohol dehydrogenase
SC10_RS21320	COG1012	belongs to the aldehyde dehydrogenase family
SC10_RS21325	COG0450	alkyl hydroperoxide reductase
SC10_RS21330	COG3634	alkyl hydroperoxide reductase activity
SC10_RS21335	COG1113	amino acid transport
SC10_RS21340	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
SC10_RS21345	COG3634	alkyl hydroperoxide reductase activity
SC10_RS21355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
SC10_RS21360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS21365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SC10_RS21380	COG1131	(ABC) transporter
SC10_RS21385	COG0842	Transport permease protein
SC10_RS21390	COG4585	Histidine kinase
SC10_RS21395	COG2197	response regulator
SC10_RS21405	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
SC10_RS21415	COG0456	acetyltransferase
SC10_RS21430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SC10_RS21435	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SC10_RS21440	COG4853	Protein conserved in bacteria
SC10_RS21445	COG4863	YycH protein
SC10_RS21450	COG5002	protein histidine kinase activity
SC10_RS21455	COG0745	RESPONSE REGULATOR receiver
SC10_RS21480	COG1051	belongs to the nudix hydrolase family
SC10_RS21485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
SC10_RS21495	COG0305	Participates in initiation and elongation during chromosome replication
SC10_RS21510	COG2807	transmembrane transport
SC10_RS21515	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
SC10_RS21520	COG0363	glucosamine-6-phosphate deaminase activity
SC10_RS21525	COG2188	Transcriptional regulator
SC10_RS21530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
SC10_RS21535	COG1263	PTS System
SC10_RS21535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SC10_RS21540	COG0359	binds to the 23S rRNA
SC10_RS21545	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
SC10_RS21550	COG4241	membrane
SC10_RS21560	COG5577	PFAM Coat F domain
SC10_RS21565	COG0589	response to stress
SC10_RS21570	COG0659	secondary active sulfate transmembrane transporter activity
SC10_RS21575	COG2271	Major facilitator Superfamily
SC10_RS21580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SC10_RS21585	COG0629	single-stranded DNA binding
SC10_RS21590	COG0360	Binds together with S18 to 16S ribosomal RNA
SC10_RS21595	COG0012	GTP binding
SC10_RS21605	COG4481	Protein conserved in bacteria
SC10_RS21610	COG3949	Membrane
SC10_RS21620	COG1475	DNA binding
SC10_RS21625	COG1192	Involved in chromosome partitioning
SC10_RS21630	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
SC10_RS21635	COG1595	DNA-templated transcription, initiation
SC10_RS21640	COG1475	DNA binding
SC10_RS21645	COG0357	Ribosomal RNA small subunit methyltransferase G
SC10_RS21650	COG0445	tRNA wobble uridine modification
SC10_RS21655	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SC10_RS21660	COG1847	R3H domain protein
SC10_RS21665	COG0706	membrane insertase activity
SC10_RS21670	COG0594	ribonuclease P activity
SC10_RS21720	COG2814	Major facilitator Superfamily
SC10_RS21720	COG0477	Major facilitator Superfamily
SC10_RS21735	COG5444	nuclease activity