locus-tag	class	description
BLMD_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLMD_RS00010	COG0592	DNA-directed DNA polymerase activity
BLMD_RS00015	COG2501	S4 domain
BLMD_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLMD_RS00030	COG0187	DNA topoisomerase II activity
BLMD_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLMD_RS00070	COG0517	IMP dehydrogenase activity
BLMD_RS00070	COG0516	GMP reductase activity
BLMD_RS00075	COG1686	Belongs to the peptidase S11 family
BLMD_RS00080	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BLMD_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BLMD_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLMD_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
BLMD_RS00100	COG2610	gluconate transmembrane transporter activity
BLMD_RS00105	COG3835	regulator
BLMD_RS00120	COG1428	Deoxynucleoside kinase
BLMD_RS00125	COG1428	Deoxynucleoside kinase
BLMD_RS00130	COG3858	chitin binding
BLMD_RS00130	COG1388	LysM domain
BLMD_RS00135	COG1335	isochorismatase
BLMD_RS00140	COG0590	tRNA wobble adenosine to inosine editing
BLMD_RS00150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLMD_RS00155	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BLMD_RS00160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLMD_RS00205	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BLMD_RS00210	COG3853	Toxic anion resistance protein (TelA)
BLMD_RS00215	COG1982	Orn Lys Arg decarboxylase major
BLMD_RS00220	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLMD_RS00225	COG3870	Protein conserved in bacteria
BLMD_RS00230	COG1728	Protein conserved in bacteria
BLMD_RS00235	COG0470	DNA polymerase III
BLMD_RS00240	COG1774	PSP1 C-terminal conserved region
BLMD_RS00245	COG4467	Involved in initiation control of chromosome replication
BLMD_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BLMD_RS00255	COG2827	Endonuclease containing a URI domain
BLMD_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLMD_RS00265	COG2002	toxin-antitoxin pair type II binding
BLMD_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_RS00275	COG0084	hydrolase, TatD family'
BLMD_RS00280	COG3583	domain protein
BLMD_RS00280	COG3584	3D domain protein
BLMD_RS00285	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLMD_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLMD_RS00300	COG4466	Protein conserved in bacteria
BLMD_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BLMD_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_RS00320	COG0251	oxidation-reduction process
BLMD_RS00325	COG2088	sporulation resulting in formation of a cellular spore
BLMD_RS00330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLMD_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLMD_RS00340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLMD_RS00345	COG0193	aminoacyl-tRNA hydrolase activity
BLMD_RS00355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLMD_RS00360	COG2002	toxin-antitoxin pair type II binding
BLMD_RS00365	COG2244	polysaccharide biosynthetic process
BLMD_RS00370	COG3956	TIGRFAM MazG family protein
BLMD_RS00375	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BLMD_RS00390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BLMD_RS00395	COG1098	S1 RNA binding domain
BLMD_RS00410	COG2208	phosphoserine phosphatase activity
BLMD_RS00415	COG2304	oxidoreductase activity
BLMD_RS00420	COG0515	serine threonine protein kinase
BLMD_RS00425	COG0037	tRNA processing
BLMD_RS00430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BLMD_RS00435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLMD_RS00440	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BLMD_RS00445	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BLMD_RS00450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLMD_RS00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_RS00465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_RS00470	COG0512	Glutamine amidotransferase of anthranilate synthase
BLMD_RS00475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLMD_RS00485	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLMD_RS00490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLMD_RS00495	COG1396	sequence-specific DNA binding
BLMD_RS00500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLMD_RS00505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLMD_RS00585	COG4463	regulation of RNA biosynthetic process
BLMD_RS00590	COG3880	PFAM UvrB UvrC protein
BLMD_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BLMD_RS00600	COG0542	response to heat
BLMD_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BLMD_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BLMD_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
BLMD_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BLMD_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BLMD_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLMD_RS00635	COG1045	serine acetyltransferase
BLMD_RS00640	COG0215	cysteine-tRNA ligase activity
BLMD_RS00645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BLMD_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLMD_RS00655	COG3688	RNA-binding protein containing a PIN domain
BLMD_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
BLMD_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLMD_RS00685	COG0081	regulation of translation
BLMD_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLMD_RS00695	COG0222	ribosome binding
BLMD_RS00700	COG2813	Specifically methylates the guanine in position
BLMD_RS00705	COG0085	RNA polymerase activity
BLMD_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLMD_RS00715	COG1358	cellular component organization or biogenesis
BLMD_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLMD_RS00725	COG0049	tRNA binding
BLMD_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLMD_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLMD_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BLMD_RS00750	COG0088	Forms part of the polypeptide exit tunnel
BLMD_RS00755	COG0089	rRNA binding
BLMD_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLMD_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLMD_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLMD_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLMD_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
BLMD_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLMD_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLMD_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLMD_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BLMD_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLMD_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLMD_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BLMD_RS00830	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLMD_RS00835	COG1841	ribosomal large subunit assembly
BLMD_RS00840	COG0200	Binds to the 23S rRNA
BLMD_RS00845	COG0201	protein transport
BLMD_RS00850	COG0563	adenylate kinase activity
BLMD_RS00855	COG0024	Methionine aminopeptidase
BLMD_RS00860	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BLMD_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLMD_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLMD_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLMD_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLMD_RS00885	COG0202	RNA polymerase activity
BLMD_RS00890	COG0203	ribosomal protein L17
BLMD_RS00895	COG1122	ATPase activity
BLMD_RS00900	COG1122	ATPase activity
BLMD_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLMD_RS00910	COG0101	tRNA pseudouridine synthase activity
BLMD_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLMD_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLMD_RS00950	COG2318	DinB family
BLMD_RS00970	COG1131	(ABC) transporter
BLMD_RS01000	COG2274	protein secretion by the type I secretion system
BLMD_RS01025	COG3290	protein histidine kinase activity
BLMD_RS01050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_RS01055	COG0489	protein tyrosine kinase activity
BLMD_RS01065	COG2194	sulfuric ester hydrolase activity
BLMD_RS01070	COG0726	polysaccharide deacetylase
BLMD_RS01100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_RS01110	COG0385	Bile acid
BLMD_RS01125	COG3876	Protein conserved in bacteria
BLMD_RS01130	COG1472	Belongs to the glycosyl hydrolase 3 family
BLMD_RS01135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_RS01140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS01140	COG1263	PTS System
BLMD_RS01145	COG1737	Transcriptional regulator
BLMD_RS01150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLMD_RS01155	COG1683	Conserved Protein
BLMD_RS01190	COG1595	DNA-templated transcription, initiation
BLMD_RS01195	COG5662	AntiSigma factor
BLMD_RS01200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLMD_RS01205	COG4856	YbbR-like protein
BLMD_RS01210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLMD_RS01215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLMD_RS01235	COG1725	Transcriptional regulator
BLMD_RS01240	COG0640	Transcriptional regulator
BLMD_RS01250	COG2814	Major facilitator Superfamily
BLMD_RS01255	COG1309	transcriptional regulator
BLMD_RS01270	COG1132	(ABC) transporter
BLMD_RS01275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLMD_RS01285	COG1132	(ABC) transporter
BLMD_RS01290	COG2312	Erythromycin esterase
BLMD_RS01310	COG1011	Hydrolase
BLMD_RS01330	COG2211	Major facilitator Superfamily
BLMD_RS01350	COG1331	Highly conserved protein containing a thioredoxin domain
BLMD_RS01355	COG0697	spore germination
BLMD_RS01360	COG0789	Transcriptional regulator
BLMD_RS01385	COG2226	methyltransferase
BLMD_RS01390	COG0076	glutamate decarboxylase activity
BLMD_RS01395	COG0778	Nitroreductase
BLMD_RS01400	COG1802	Transcriptional regulator
BLMD_RS01405	COG0730	response to heat
BLMD_RS01425	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLMD_RS01430	COG4682	membrane
BLMD_RS01455	COG0697	spore germination
BLMD_RS01460	COG1917	Cupin 2, conserved barrel domain protein
BLMD_RS01460	COG2207	Transcriptional regulator
BLMD_RS01470	COG2197	response regulator
BLMD_RS01485	COG0371	Dehydrogenase
BLMD_RS01500	COG4257	antibiotic catabolic process
BLMD_RS01510	COG0833	amino acid
BLMD_RS01515	COG2040	homocysteine
BLMD_RS01525	COG1263	PTS System
BLMD_RS01525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS01530	COG0789	Transcriptional regulator
BLMD_RS01535	COG2323	membrane
BLMD_RS01540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BLMD_RS01540	COG4451	ribulose bisphosphate carboxylase, small
BLMD_RS01550	COG2205	protein histidine kinase activity
BLMD_RS01555	COG1115	amino acid carrier protein
BLMD_RS01560	COG2066	Belongs to the glutaminase family
BLMD_RS01565	COG4191	Histidine kinase
BLMD_RS01570	COG0784	Response regulator, receiver
BLMD_RS01595	COG3540	Alkaline phosphatase
BLMD_RS01600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLMD_RS01605	COG0805	protein transport
BLMD_RS01610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_RS01615	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS01620	COG2271	Major facilitator Superfamily
BLMD_RS01625	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_RS01630	COG2186	Transcriptional regulator
BLMD_RS01635	COG2721	sulfolactate sulfo-lyase activity
BLMD_RS01655	COG0745	RESPONSE REGULATOR receiver
BLMD_RS01660	COG2205	protein histidine kinase activity
BLMD_RS01665	COG1131	(ABC) transporter
BLMD_RS01690	COG3173	Aminoglycoside phosphotransferase
BLMD_RS01695	COG1846	Transcriptional regulator
BLMD_RS01700	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS01720	COG0789	Transcriptional regulator
BLMD_RS01745	COG0697	spore germination
BLMD_RS01755	COG1405	negative regulation of cell septum assembly
BLMD_RS01755	COG3012	SEC-C Motif Domain Protein
BLMD_RS01760	COG1131	(ABC) transporter
BLMD_RS01785	COG0583	DNA-binding transcription factor activity
BLMD_RS01790	COG1942	4-Oxalocrotonate Tautomerase
BLMD_RS01795	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS01810	COG1288	antiporter activity
BLMD_RS01820	COG0252	asparaginase activity
BLMD_RS01825	COG0456	acetyltransferase
BLMD_RS01835	COG1164	Oligoendopeptidase f
BLMD_RS01840	COG2261	transglycosylase associated protein
BLMD_RS01850	COG0247	lactate metabolic process
BLMD_RS01855	COG0277	FAD linked oxidase domain protein
BLMD_RS01860	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS01865	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_RS01870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS01875	COG1486	melibiose metabolic process
BLMD_RS01880	COG2188	Transcriptional regulator
BLMD_RS01885	COG3394	polysaccharide catabolic process
BLMD_RS01900	COG3591	Belongs to the peptidase S1B family
BLMD_RS01905	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS01915	COG1595	DNA-templated transcription, initiation
BLMD_RS01925	COG3773	Cell wall hydrolase
BLMD_RS01930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_RS01935	COG0791	NLP P60 protein
BLMD_RS01935	COG3883	PFAM NLP P60 protein
BLMD_RS01945	COG1131	(ABC) transporter
BLMD_RS01950	COG1309	transcriptional regulator
BLMD_RS01965	COG2310	stress, protein
BLMD_RS01970	COG2310	stress, protein
BLMD_RS01975	COG2310	stress, protein
BLMD_RS01980	COG0861	Integral membrane protein TerC family
BLMD_RS02000	COG3853	Toxic anion resistance protein (TelA)
BLMD_RS02005	COG0785	Cytochrome C biogenesis protein
BLMD_RS02015	COG0789	Transcriptional regulator
BLMD_RS02020	COG2223	nitrite transmembrane transporter activity
BLMD_RS02025	COG0039	L-malate dehydrogenase activity
BLMD_RS02030	COG1620	l-lactate permease
BLMD_RS02035	COG1280	lysine exporter protein (LysE YggA)
BLMD_RS02040	COG1113	amino acid transport
BLMD_RS02045	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BLMD_RS02050	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLMD_RS02055	COG3541	Predicted nucleotidyltransferase
BLMD_RS02065	COG0506	proline dehydrogenase activity
BLMD_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS02075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS02080	COG2508	Transcriptional regulator
BLMD_RS02085	COG3689	TIGRFAM TIGR03943 family protein
BLMD_RS02090	COG0701	Predicted permease
BLMD_RS02095	COG3458	cephalosporin-C deacetylase activity
BLMD_RS02100	COG1846	Transcriptional regulator
BLMD_RS02115	COG0765	amino acid transport
BLMD_RS02120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_RS02125	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS02135	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS02145	COG3209	COG3209 Rhs family protein
BLMD_RS02155	COG0515	serine threonine protein kinase
BLMD_RS02160	COG0840	transmembrane signaling receptor activity
BLMD_RS02160	COG3290	protein histidine kinase activity
BLMD_RS02165	COG5444	nuclease activity
BLMD_RS02185	COG3842	ATPase activity
BLMD_RS02195	COG1177	transmembrane transport
BLMD_RS02205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS02210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS02215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS02220	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BLMD_RS02225	COG0697	spore germination
BLMD_RS02230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS02240	COG2819	hydrolase of the alpha beta superfamily
BLMD_RS02245	COG2207	Transcriptional regulator
BLMD_RS02245	COG3708	Transcriptional regulator
BLMD_RS02250	COG2364	Membrane
BLMD_RS02280	COG1126	abc transporter atp-binding protein
BLMD_RS02285	COG0765	amino acid transport
BLMD_RS02290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_RS02295	COG3829	transcription factor binding
BLMD_RS02300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLMD_RS02305	COG0833	amino acid
BLMD_RS02310	COG0010	Belongs to the arginase family
BLMD_RS02315	COG0583	DNA-binding transcription factor activity
BLMD_RS02320	COG0163	prenyltransferase activity
BLMD_RS02325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BLMD_RS02395	COG5444	nuclease activity
BLMD_RS02415	COG2972	Histidine kinase
BLMD_RS02420	COG2207	Transcriptional regulator
BLMD_RS02420	COG4753	response regulator
BLMD_RS02425	COG4213	ABC transporter substrate-binding protein
BLMD_RS02435	COG4214	carbohydrate transport
BLMD_RS02440	COG2271	Major facilitator Superfamily
BLMD_RS02445	COG1846	Transcriptional regulator
BLMD_RS02445	COG0456	acetyltransferase
BLMD_RS02450	COG1874	Beta-galactosidase
BLMD_RS02455	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
BLMD_RS02465	COG3104	oligopeptide transport
BLMD_RS02470	COG5434	Belongs to the glycosyl hydrolase 28 family
BLMD_RS02480	COG0697	spore germination
BLMD_RS02490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BLMD_RS02495	COG0789	Transcriptional regulator
BLMD_RS02500	COG1136	(ABC) transporter
BLMD_RS02505	COG0577	efflux transmembrane transporter activity
BLMD_RS02510	COG0745	RESPONSE REGULATOR receiver
BLMD_RS02515	COG3850	Histidine kinase
BLMD_RS02515	COG5002	protein histidine kinase activity
BLMD_RS02520	COG0840	transmembrane signaling receptor activity
BLMD_RS02525	COG0527	aspartate kinase activity
BLMD_RS02530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS02535	COG4605	iron ion homeostasis
BLMD_RS02540	COG4604	ABC transporter, ATP-binding protein
BLMD_RS02545	COG4607	ABC-type enterochelin transport system periplasmic component
BLMD_RS02550	COG2814	Major facilitator Superfamily
BLMD_RS02555	COG1309	transcriptional regulator
BLMD_RS02565	COG0778	Nitroreductase
BLMD_RS02570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLMD_RS02575	COG0640	Transcriptional regulator
BLMD_RS02580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS02585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLMD_RS02590	COG0531	amino acid
BLMD_RS02595	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS02600	COG0697	spore germination
BLMD_RS02610	COG4549	nuclear export factor GLE1
BLMD_RS02615	COG2372	response to copper ion
BLMD_RS02615	COG1276	copper resistance
BLMD_RS02620	COG1349	DNA-binding transcription factor activity
BLMD_RS02625	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_RS02630	COG0243	molybdopterin cofactor binding
BLMD_RS02635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_RS02640	COG2146	nitrite reductase [NAD(P)H] activity
BLMD_RS02645	COG1587	Uroporphyrinogen-III synthase
BLMD_RS02645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLMD_RS02650	COG1802	Transcriptional regulator
BLMD_RS02655	COG0471	metal ion transport
BLMD_RS02660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLMD_RS02670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS02685	COG3959	Transketolase, thiamine diphosphate binding domain
BLMD_RS02690	COG3958	Transketolase
BLMD_RS02695	COG0561	phosphatase activity
BLMD_RS02700	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BLMD_RS02705	COG1914	H( )-stimulated, divalent metal cation uptake system
BLMD_RS02710	COG4336	lyase activity
BLMD_RS02715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BLMD_RS02720	COG1984	allophanate hydrolase subunit 2
BLMD_RS02725	COG1414	Transcriptional regulator
BLMD_RS02730	COG2755	lipolytic protein G-D-S-L family
BLMD_RS02735	COG2213	PTS system mannitol-specific
BLMD_RS02740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS02745	COG0246	Mannitol dehydrogenase
BLMD_RS02750	COG3711	transcriptional antiterminator
BLMD_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS02760	COG1917	Cupin 2, conserved barrel domain protein
BLMD_RS02770	COG3871	stress protein (general stress protein 26)
BLMD_RS02785	COG2814	Major facilitator Superfamily
BLMD_RS02795	COG1522	sequence-specific DNA binding
BLMD_RS02800	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLMD_RS02800	COG0551	DNA topoisomerase type I activity
BLMD_RS02805	COG0287	Prephenate dehydrogenase
BLMD_RS02810	COG0512	Glutamine amidotransferase of anthranilate synthase
BLMD_RS02810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_RS02815	COG1605	Chorismate mutase
BLMD_RS02820	COG0028	Belongs to the TPP enzyme family
BLMD_RS02825	COG3397	chitin binding
BLMD_RS02835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_RS02840	COG1914	H( )-stimulated, divalent metal cation uptake system
BLMD_RS02845	COG2261	transglycosylase associated protein
BLMD_RS02850	COG1027	Aspartate ammonia-lyase
BLMD_RS02855	COG1819	glycosyl
BLMD_RS02860	COG4876	unkown
BLMD_RS02865	COG2217	Heavy metal translocating P-type atpase
BLMD_RS02875	COG0662	Cupin 2, conserved barrel domain protein
BLMD_RS02885	COG0628	permease
BLMD_RS02890	COG1301	dicarboxylic acid transport
BLMD_RS02895	COG1131	(ABC) transporter
BLMD_RS02900	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_RS02910	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS02925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS02930	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLMD_RS02935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLMD_RS02945	COG0513	Belongs to the DEAD box helicase family
BLMD_RS02950	COG3402	PFAM membrane-flanked domain
BLMD_RS02955	COG3428	Bacterial PH domain
BLMD_RS02960	COG0705	Rhomboid family
BLMD_RS02965	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BLMD_RS02970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLMD_RS02975	COG0864	Transcriptional regulator
BLMD_RS02980	COG2337	Toxic component of a toxin-antitoxin (TA) module
BLMD_RS02985	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_RS02990	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_RS02995	COG2172	sigma factor antagonist activity
BLMD_RS03000	COG2208	phosphoserine phosphatase activity
BLMD_RS03015	COG1191	sigma factor activity
BLMD_RS03020	COG2208	phosphoserine phosphatase activity
BLMD_RS03025	COG2183	response to ionizing radiation
BLMD_RS03030	COG1309	transcriptional regulator
BLMD_RS03040	COG2409	Drug exporters of the RND superfamily
BLMD_RS03040	COG1033	growth of symbiont in host cell
BLMD_RS03045	COG3091	SprT-like family
BLMD_RS03110	COG0726	polysaccharide deacetylase
BLMD_RS03115	COG3239	Fatty acid desaturase
BLMD_RS03120	COG1278	Cold shock
BLMD_RS03125	COG1329	Transcriptional regulator
BLMD_RS03135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS03140	COG0477	Major facilitator Superfamily
BLMD_RS03150	COG2364	Membrane
BLMD_RS03155	COG1846	Transcriptional regulator
BLMD_RS03160	COG0456	acetyltransferase
BLMD_RS03165	COG2808	Putative FMN-binding domain
BLMD_RS03175	COG1733	regulation of RNA biosynthetic process
BLMD_RS03180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS03195	COG3545	Serine hydrolase
BLMD_RS03200	COG1733	regulation of RNA biosynthetic process
BLMD_RS03215	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BLMD_RS03220	COG1113	amino acid transport
BLMD_RS03235	COG0596	Alpha beta hydrolase
BLMD_RS03240	COG5566	PFAM Mor transcription activator
BLMD_RS03245	COG1595	DNA-templated transcription, initiation
BLMD_RS03255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLMD_RS03255	COG2755	lipolytic protein G-D-S-L family
BLMD_RS03260	COG0494	nUDIX hydrolase
BLMD_RS03265	COG2814	Major facilitator Superfamily
BLMD_RS03270	COG1979	alcohol dehydrogenase
BLMD_RS03275	COG0745	RESPONSE REGULATOR receiver
BLMD_RS03275	COG2972	Histidine kinase
BLMD_RS03280	COG3279	Response regulator of the LytR AlgR family
BLMD_RS03290	COG3764	Sortase (surface protein transpeptidase)
BLMD_RS03300	COG2814	Major facilitator Superfamily
BLMD_RS03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BLMD_RS03345	COG0802	atpase or kinase
BLMD_RS03350	COG1214	PFAM Peptidase M22, glycoprotease
BLMD_RS03355	COG0456	acetyltransferase
BLMD_RS03360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLMD_RS03365	COG0488	(ABC) transporter
BLMD_RS03370	COG0315	cyclic pyranopterin monophosphate synthase activity
BLMD_RS03375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BLMD_RS03380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLMD_RS03385	COG0805	protein transport
BLMD_RS03395	COG1266	CAAX protease self-immunity
BLMD_RS03400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLMD_RS03405	COG0459	protein refolding
BLMD_RS03420	COG2720	vancomycin resistance protein
BLMD_RS03440	COG2135	peptidase activity
BLMD_RS03450	COG1309	transcriptional regulator
BLMD_RS03455	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_RS03455	COG3848	Pyruvate phosphate dikinase
BLMD_RS03465	COG3189	MarR family transcriptional regulator
BLMD_RS03470	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BLMD_RS03475	COG2272	Belongs to the type-B carboxylesterase lipase family
BLMD_RS03480	COG2814	Major facilitator Superfamily
BLMD_RS03485	COG1842	Phage shock protein A
BLMD_RS03490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLMD_RS03495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BLMD_RS03500	COG4260	virion core protein, lumpy skin disease virus
BLMD_RS03510	COG1378	Sugar-specific transcriptional regulator TrmB
BLMD_RS03515	COG1280	lysine exporter protein (LysE YggA)
BLMD_RS03520	COG3339	Conserved Protein
BLMD_RS03525	COG0772	Belongs to the SEDS family
BLMD_RS03530	COG0772	Belongs to the SEDS family
BLMD_RS03550	COG0726	polysaccharide deacetylase
BLMD_RS03560	COG1609	Transcriptional regulator
BLMD_RS03565	COG0366	Alpha amylase catalytic
BLMD_RS03570	COG2182	Extracellular solute-binding protein
BLMD_RS03575	COG1175	transmembrane transport
BLMD_RS03580	COG3833	ABC-type maltose transport systems, permease component
BLMD_RS03585	COG5521	maltodextrose utilization protein MalA
BLMD_RS03590	COG1554	hydrolase, family 65, central catalytic
BLMD_RS03595	COG0366	Alpha amylase catalytic
BLMD_RS03600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLMD_RS03605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLMD_RS03610	COG1846	Transcriptional regulator
BLMD_RS03625	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BLMD_RS03630	COG0823	Involved in the tonB-independent uptake of proteins
BLMD_RS03660	COG0702	epimerase
BLMD_RS03670	COG2132	Multicopper oxidase
BLMD_RS03690	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLMD_RS03695	COG0714	Associated with various cellular activities
BLMD_RS03700	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BLMD_RS03705	COG1305	Transglutaminase-like
BLMD_RS03710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLMD_RS03710	COG0519	Catalyzes the synthesis of GMP from XMP
BLMD_RS03720	COG2252	PERMEase
BLMD_RS03735	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BLMD_RS03745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLMD_RS03750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLMD_RS03755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLMD_RS03760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLMD_RS03765	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLMD_RS03770	COG0047	phosphoribosylformylglycinamidine synthase activity
BLMD_RS03775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLMD_RS03780	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLMD_RS03785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BLMD_RS03790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLMD_RS03795	COG0138	bifunctional purine biosynthesis protein purh
BLMD_RS03800	COG0151	Belongs to the GarS family
BLMD_RS03810	COG2124	cytochrome p450
BLMD_RS03830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLMD_RS03835	COG1470	cell adhesion involved in biofilm formation
BLMD_RS03840	COG4496	protein, YerC YecD
BLMD_RS03845	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BLMD_RS03850	COG0210	DNA helicase
BLMD_RS03855	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLMD_RS03860	COG4851	CamS sex pheromone cAM373 precursor
BLMD_RS03865	COG2188	Transcriptional regulator
BLMD_RS03885	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BLMD_RS03890	COG0626	cystathionine gamma-synthase activity
BLMD_RS03895	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLMD_RS03900	COG3457	Alanine racemase
BLMD_RS03905	COG0363	glucosamine-6-phosphate deaminase activity
BLMD_RS03910	COG1285	pathogenesis
BLMD_RS03915	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS03920	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLMD_RS03925	COG0154	amidase activity
BLMD_RS03930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLMD_RS03945	COG4124	Belongs to the glycosyl hydrolase 26 family
BLMD_RS03950	COG1309	transcriptional regulator
BLMD_RS03955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BLMD_RS03965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_RS03970	COG1957	nucleoside hydrolase
BLMD_RS03975	COG1597	lipid kinase activity
BLMD_RS03980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLMD_RS04010	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS04015	COG3711	transcriptional antiterminator
BLMD_RS04020	COG0457	Tetratricopeptide repeat
BLMD_RS04035	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BLMD_RS04035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_RS04040	COG3586	endonuclease activity
BLMD_RS04045	COG0697	spore germination
BLMD_RS04050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS04055	COG0697	spore germination
BLMD_RS04060	COG0217	transcriptional regulatory protein
BLMD_RS04090	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS04095	COG0840	transmembrane signaling receptor activity
BLMD_RS04100	COG0109	protoheme IX farnesyltransferase activity
BLMD_RS04105	COG1309	transcriptional regulator
BLMD_RS04110	COG0471	metal ion transport
BLMD_RS04115	COG0488	(ABC) transporter
BLMD_RS04120	COG0583	DNA-binding transcription factor activity
BLMD_RS04130	COG0640	Transcriptional regulator
BLMD_RS04135	COG1469	GTP cyclohydrolase I activity
BLMD_RS04150	COG0523	cobalamin synthesis protein
BLMD_RS04160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLMD_RS04165	COG0156	8-amino-7-oxononanoate synthase activity
BLMD_RS04170	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BLMD_RS04175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BLMD_RS04180	COG2124	cytochrome p450
BLMD_RS04190	COG0789	Transcriptional regulator
BLMD_RS04195	COG2814	Major facilitator Superfamily
BLMD_RS04205	COG0488	(ABC) transporter
BLMD_RS04210	COG0513	Belongs to the DEAD box helicase family
BLMD_RS04215	COG2130	NADP-dependent
BLMD_RS04230	COG0471	metal ion transport
BLMD_RS04240	COG1136	(ABC) transporter
BLMD_RS04260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS04270	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BLMD_RS04275	COG3858	chitin binding
BLMD_RS04280	COG5658	integral membrane protein
BLMD_RS04285	COG0640	Transcriptional regulator
BLMD_RS04290	COG1254	Belongs to the acylphosphatase family
BLMD_RS04295	COG2258	MOSC domain
BLMD_RS04305	COG0024	Methionine aminopeptidase
BLMD_RS04310	COG1368	sulfuric ester hydrolase activity
BLMD_RS04320	COG1115	amino acid carrier protein
BLMD_RS04325	COG1263	PTS System
BLMD_RS04325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS04330	COG0366	Alpha amylase catalytic
BLMD_RS04335	COG2188	Transcriptional regulator
BLMD_RS04360	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_RS04365	COG1045	serine acetyltransferase
BLMD_RS04370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_RS04380	COG1215	transferase activity, transferring glycosyl groups
BLMD_RS04385	COG0457	Tetratricopeptide repeat
BLMD_RS04385	COG0463	Glycosyl transferase, family 2
BLMD_RS04395	COG0673	inositol 2-dehydrogenase activity
BLMD_RS04410	COG1733	regulation of RNA biosynthetic process
BLMD_RS04415	COG0778	Nitroreductase
BLMD_RS04420	COG0737	Belongs to the 5'-nucleotidase family
BLMD_RS04425	COG0693	protein deglycase activity
BLMD_RS04430	COG4840	Belongs to the UPF0435 family
BLMD_RS04435	COG1115	amino acid carrier protein
BLMD_RS04440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_RS04445	COG4980	gas vesicle protein
BLMD_RS04450	COG1295	ribonuclease BN
BLMD_RS04455	COG0477	Major facilitator Superfamily
BLMD_RS04465	COG0387	Pfam Sodium calcium exchanger
BLMD_RS04475	COG0535	radical SAM domain protein
BLMD_RS04485	COG0726	polysaccharide deacetylase
BLMD_RS04490	COG0371	Dehydrogenase
BLMD_RS04500	COG0598	Magnesium transport protein CorA
BLMD_RS04505	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BLMD_RS04510	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLMD_RS04515	COG4637	Psort location Cytoplasmic, score
BLMD_RS04540	COG1819	glycosyl
BLMD_RS04550	COG0477	Major facilitator Superfamily
BLMD_RS04560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS04560	COG1263	PTS System
BLMD_RS04565	COG3711	transcriptional antiterminator
BLMD_RS04570	COG0288	reversible hydration of carbon dioxide
BLMD_RS04575	COG3002	Belongs to the UPF0753 family
BLMD_RS04580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLMD_RS04585	COG5609	conserved protein (DUF2294)
BLMD_RS04595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_RS04600	COG0022	dehydrogenase e1 component
BLMD_RS04605	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_RS04610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_RS04615	COG3284	Transcriptional regulator
BLMD_RS04620	COG1742	UPF0060 membrane protein
BLMD_RS04625	COG1486	melibiose metabolic process
BLMD_RS04630	COG1737	Transcriptional regulator
BLMD_RS04635	COG1263	PTS System
BLMD_RS04635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS04650	COG1733	regulation of RNA biosynthetic process
BLMD_RS04655	COG2259	Doxx family
BLMD_RS04660	COG2514	catechol 2,3-dioxygenase activity
BLMD_RS04670	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS04675	COG1917	Cupin 2, conserved barrel domain protein
BLMD_RS04675	COG2207	Transcriptional regulator
BLMD_RS04680	COG1653	transport
BLMD_RS04690	COG1051	belongs to the nudix hydrolase family
BLMD_RS04700	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLMD_RS04700	COG0392	lysyltransferase activity
BLMD_RS04705	COG0384	phenazine biosynthesis protein PhzF
BLMD_RS04710	COG0778	Nitroreductase
BLMD_RS04730	COG1090	epimerase
BLMD_RS04735	COG2137	regulation of response to DNA damage stimulus
BLMD_RS04760	COG0463	Glycosyl transferase, family 2
BLMD_RS04770	COG4485	Bacterial membrane protein, YfhO
BLMD_RS04775	COG1988	membrane-bound metal-dependent
BLMD_RS04780	COG1194	a g-specific adenine glycosylase
BLMD_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS04805	COG3557	Belongs to the UPF0374 family
BLMD_RS04810	COG1132	(ABC) transporter
BLMD_RS04815	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS04820	COG4608	Belongs to the ABC transporter superfamily
BLMD_RS04825	COG0747	negative chemotaxis
BLMD_RS04830	COG0601	transmembrane transport
BLMD_RS04835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS04840	COG4129	membrane
BLMD_RS04845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLMD_RS04850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BLMD_RS04855	COG0735	belongs to the Fur family
BLMD_RS04965	COG0457	Tetratricopeptide repeat
BLMD_RS04985	COG5444	nuclease activity
BLMD_RS05010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLMD_RS05030	COG0710	3-dehydroquinate dehydratase activity
BLMD_RS05035	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BLMD_RS05040	COG1116	anion transmembrane transporter activity
BLMD_RS05045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLMD_RS05050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLMD_RS05055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_RS05065	COG1476	TRANSCRIPTIONal
BLMD_RS05075	COG1131	(ABC) transporter
BLMD_RS05095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_RS05105	COG3382	B3 4 domain protein
BLMD_RS05110	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BLMD_RS05120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLMD_RS05125	COG0789	Transcriptional regulator
BLMD_RS05130	COG1664	Polymer-forming cytoskeletal
BLMD_RS05135	COG1664	Polymer-forming cytoskeletal
BLMD_RS05140	COG2766	serine protein kinase
BLMD_RS05145	COG2718	Belongs to the UPF0229 family
BLMD_RS05150	COG1566	PFAM secretion protein HlyD family protein
BLMD_RS05155	COG2814	Major facilitator Superfamily
BLMD_RS05160	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS05170	COG1131	(ABC) transporter
BLMD_RS05175	COG1131	(ABC) transporter
BLMD_RS05180	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_RS05185	COG1278	Cold shock
BLMD_RS05190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLMD_RS05195	COG2011	ABC-type metal ion transport system permease component
BLMD_RS05200	COG1464	Belongs to the NlpA lipoprotein family
BLMD_RS05205	COG1823	symporter activity
BLMD_RS05230	COG5577	PFAM Coat F domain
BLMD_RS05240	COG5002	protein histidine kinase activity
BLMD_RS05245	COG1525	nuclease
BLMD_RS05245	COG0737	Belongs to the 5'-nucleotidase family
BLMD_RS05245	COG4085	toxin activity
BLMD_RS05250	COG3764	Sortase (surface protein transpeptidase)
BLMD_RS05255	COG0564	pseudouridine synthase activity
BLMD_RS05265	COG0517	IMP dehydrogenase activity
BLMD_RS05270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLMD_RS05275	COG3153	acetyltransferase
BLMD_RS05275	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLMD_RS05280	COG0488	(ABC) transporter
BLMD_RS05285	COG2116	formate transmembrane transporter activity
BLMD_RS05300	COG0604	alcohol dehydrogenase
BLMD_RS05305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BLMD_RS05310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLMD_RS05315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BLMD_RS05320	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLMD_RS05325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLMD_RS05340	COG4585	Histidine kinase
BLMD_RS05340	COG2203	Gaf domain
BLMD_RS05345	COG2197	response regulator
BLMD_RS05350	COG0431	NADPH-dependent FMN reductase
BLMD_RS05365	COG1959	2 iron, 2 sulfur cluster binding
BLMD_RS05370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BLMD_RS05370	COG1017	nitric oxide dioxygenase activity
BLMD_RS05375	COG2719	SpoVR family
BLMD_RS05380	COG1388	LysM domain
BLMD_RS05380	COG0791	NLP P60 protein
BLMD_RS05385	COG0583	DNA-binding transcription factor activity
BLMD_RS05390	COG0372	Belongs to the citrate synthase family
BLMD_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS05405	COG0733	neurotransmitter:sodium symporter activity
BLMD_RS05435	COG2207	Transcriptional regulator
BLMD_RS05435	COG3708	Transcriptional regulator
BLMD_RS05440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS05460	COG1595	DNA-templated transcription, initiation
BLMD_RS05465	COG0662	Cupin 2, conserved barrel domain protein
BLMD_RS05470	COG0667	Aldo Keto reductase
BLMD_RS05475	COG0204	Acyl-transferase
BLMD_RS05480	COG3152	Membrane
BLMD_RS05495	COG1253	flavin adenine dinucleotide binding
BLMD_RS05500	COG0789	Transcriptional regulator
BLMD_RS05505	COG1253	flavin adenine dinucleotide binding
BLMD_RS05525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMD_RS05530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLMD_RS05535	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_RS05540	COG0668	transmembrane transport
BLMD_RS05545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLMD_RS05555	COG0726	polysaccharide deacetylase
BLMD_RS05565	COG1757	Na H antiporter
BLMD_RS05570	COG2017	converts alpha-aldose to the beta-anomer
BLMD_RS05605	COG0589	response to stress
BLMD_RS05610	COG1132	(ABC) transporter
BLMD_RS05615	COG1132	(ABC) transporter
BLMD_RS05620	COG0702	epimerase
BLMD_RS05635	COG3842	ATPase activity
BLMD_RS05640	COG2508	Transcriptional regulator
BLMD_RS05650	COG0189	ligase activity
BLMD_RS05655	COG0189	ligase activity
BLMD_RS05660	COG4399	Belongs to the UPF0754 family
BLMD_RS05665	COG3679	Belongs to the UPF0342 family
BLMD_RS05675	COG0561	phosphatase activity
BLMD_RS05680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLMD_RS05685	COG0475	glutathione-regulated potassium exporter activity
BLMD_RS05690	COG0490	domain, Protein
BLMD_RS05700	COG1024	Enoyl-CoA hydratase
BLMD_RS05705	COG0457	Tetratricopeptide repeat
BLMD_RS05720	COG4152	abc transporter atp-binding protein
BLMD_RS05725	COG1668	transmembrane transport
BLMD_RS05730	COG0420	3'-5' exonuclease activity
BLMD_RS05735	COG4717	serine-type aminopeptidase activity
BLMD_RS05740	COG3481	metal-dependent phosphohydrolase, HD sub domain
BLMD_RS05750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLMD_RS05780	COG1846	Transcriptional regulator
BLMD_RS05785	COG4980	gas vesicle protein
BLMD_RS05800	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLMD_RS05805	COG0537	adenosine 5'-monophosphoramidase activity
BLMD_RS05815	COG1131	(ABC) transporter
BLMD_RS05820	COG4473	ABC transporter
BLMD_RS05830	COG1473	amidohydrolase
BLMD_RS05835	COG3069	C4-dicarboxylate transmembrane transporter activity
BLMD_RS05840	COG2329	Antibiotic biosynthesis monooxygenase
BLMD_RS05845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_RS05850	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BLMD_RS05855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BLMD_RS05860	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BLMD_RS05865	COG1309	transcriptional regulator
BLMD_RS05870	COG1511	domain protein
BLMD_RS05875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_RS05880	COG1363	Peptidase, m42
BLMD_RS05890	COG1301	dicarboxylic acid transport
BLMD_RS05900	COG1234	tRNA 3'-trailer cleavage
BLMD_RS05905	COG0095	Lipoate-protein ligase
BLMD_RS05910	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS05920	COG1396	sequence-specific DNA binding
BLMD_RS05935	COG0501	Belongs to the peptidase M48B family
BLMD_RS05945	COG0697	spore germination
BLMD_RS05950	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BLMD_RS05960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS05965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS05970	COG0406	alpha-ribazole phosphatase activity
BLMD_RS05975	COG0840	transmembrane signaling receptor activity
BLMD_RS05980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLMD_RS05980	COG0723	plastoquinol--plastocyanin reductase activity
BLMD_RS05985	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS05995	COG4903	ComK protein
BLMD_RS06005	COG0398	Pfam SNARE associated Golgi protein
BLMD_RS06010	COG0681	Belongs to the peptidase S26 family
BLMD_RS06020	COG1404	Belongs to the peptidase S8 family
BLMD_RS06030	COG2508	Transcriptional regulator
BLMD_RS06035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLMD_RS06040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_RS06045	COG3257	ureidoglycine aminohydrolase activity
BLMD_RS06050	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLMD_RS06055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BLMD_RS06060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_RS06065	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_RS06075	COG0549	Belongs to the carbamate kinase family
BLMD_RS06080	COG2814	Major facilitator Superfamily
BLMD_RS06090	COG0457	Tetratricopeptide repeat
BLMD_RS06105	COG1609	Transcriptional regulator
BLMD_RS06110	COG1653	transport
BLMD_RS06115	COG1175	transmembrane transport
BLMD_RS06120	COG0395	ABC-type sugar transport system, permease component
BLMD_RS06125	COG1486	melibiose metabolic process
BLMD_RS06130	COG3180	Ammonia monooxygenase
BLMD_RS06145	COG3546	catalase activity
BLMD_RS06150	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS06155	COG2814	Major facilitator Superfamily
BLMD_RS06155	COG0477	Major facilitator Superfamily
BLMD_RS06160	COG4533	DNA binding
BLMD_RS06170	COG5002	protein histidine kinase activity
BLMD_RS06175	COG0745	RESPONSE REGULATOR receiver
BLMD_RS06180	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BLMD_RS06185	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLMD_RS06190	COG4149	molybdate abc transporter
BLMD_RS06195	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLMD_RS06200	COG1074	ATP-dependent DNA helicase activity
BLMD_RS06205	COG0420	3'-5' exonuclease activity
BLMD_RS06210	COG0419	ATPase involved in DNA repair
BLMD_RS06255	COG5337	Spore coat protein CotH
BLMD_RS06265	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLMD_RS06290	COG0367	asparagine synthase
BLMD_RS06295	COG0004	ammonium transporteR
BLMD_RS06300	COG0347	Belongs to the P(II) protein family
BLMD_RS06305	COG0534	Mate efflux family protein
BLMD_RS06310	COG1917	Cupin 2, conserved barrel domain protein
BLMD_RS06310	COG2207	Transcriptional regulator
BLMD_RS06320	COG1609	Transcriptional regulator
BLMD_RS06325	COG0673	inositol 2-dehydrogenase activity
BLMD_RS06340	COG0697	spore germination
BLMD_RS06345	COG1279	arginine transmembrane transporter activity
BLMD_RS06350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS06360	COG0076	glutamate decarboxylase activity
BLMD_RS06385	COG2153	protein acetylation
BLMD_RS06390	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS06395	COG2378	regulation of single-species biofilm formation
BLMD_RS06400	COG1410	methionine synthase
BLMD_RS06400	COG0646	methionine synthase
BLMD_RS06405	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLMD_RS06405	COG0646	methionine synthase
BLMD_RS06410	COG1666	GTP binding
BLMD_RS06415	COG2996	Protein conserved in bacteria
BLMD_RS06425	COG1307	EDD domain protein, DegV family
BLMD_RS06430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS06440	COG0516	GMP reductase activity
BLMD_RS06450	COG0561	phosphatase activity
BLMD_RS06455	COG1073	alpha beta
BLMD_RS06460	COG2151	metal-sulfur cluster biosynthetic enzyme
BLMD_RS06470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLMD_RS06475	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLMD_RS06480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLMD_RS06485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLMD_RS06490	COG0505	Belongs to the CarA family
BLMD_RS06495	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLMD_RS06500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLMD_RS06505	COG1968	undecaprenyl-diphosphatase activity
BLMD_RS06520	COG2267	carboxylic ester hydrolase activity
BLMD_RS06530	COG1744	ABC transporter substrate-binding protein PnrA-like
BLMD_RS06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_RS06550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLMD_RS06555	COG5504	Zn-dependent protease
BLMD_RS06560	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS06565	COG4608	Belongs to the ABC transporter superfamily
BLMD_RS06575	COG0601	transmembrane transport
BLMD_RS06580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS06595	COG0180	Tryptophanyl-tRNA synthetase
BLMD_RS06605	COG4166	transmembrane transport
BLMD_RS06610	COG0601	transmembrane transport
BLMD_RS06615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS06620	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS06625	COG4608	Belongs to the ABC transporter superfamily
BLMD_RS06630	COG0456	acetyltransferase
BLMD_RS06635	COG1393	Belongs to the ArsC family
BLMD_RS06640	COG0861	Integral membrane protein TerC family
BLMD_RS06645	COG4862	establishment of competence for transformation
BLMD_RS06670	COG4565	transcriptional regulatory protein
BLMD_RS06675	COG3290	protein histidine kinase activity
BLMD_RS06680	COG4469	Competence protein
BLMD_RS06685	COG1164	Oligoendopeptidase f
BLMD_RS06695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BLMD_RS06700	COG2346	COG2346, Truncated hemoglobins
BLMD_RS06710	COG0741	lytic transglycosylase activity
BLMD_RS06715	COG4116	CYTH
BLMD_RS06725	COG2357	RelA SpoT domain protein
BLMD_RS06730	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLMD_RS06735	COG0564	pseudouridine synthase activity
BLMD_RS06740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLMD_RS06750	COG0475	glutathione-regulated potassium exporter activity
BLMD_RS06750	COG0569	domain protein
BLMD_RS06755	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLMD_RS06760	COG0352	thiamine-phosphate diphosphorylase activity
BLMD_RS06770	COG2104	thiamine diphosphate biosynthetic process
BLMD_RS06775	COG2022	thiamine diphosphate biosynthetic process
BLMD_RS06780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLMD_RS06785	COG0351	phosphomethylpyrimidine kinase
BLMD_RS06790	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLMD_RS06845	COG0210	DNA helicase
BLMD_RS06855	COG0586	Pfam SNARE associated Golgi protein
BLMD_RS06860	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_RS06865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLMD_RS06870	COG2246	polysaccharide biosynthetic process
BLMD_RS06875	COG2153	protein acetylation
BLMD_RS06880	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLMD_RS06885	COG2382	esterase
BLMD_RS06905	COG0626	cystathionine gamma-synthase activity
BLMD_RS06910	COG0626	cystathionine gamma-synthase activity
BLMD_RS06915	COG5505	Protein of unknown function (DUF819)
BLMD_RS06930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_RS06940	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS07015	COG0110	maltose O-acetyltransferase activity
BLMD_RS07025	COG0583	DNA-binding transcription factor activity
BLMD_RS07030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLMD_RS07035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLMD_RS07040	COG0583	DNA-binding transcription factor activity
BLMD_RS07050	COG0346	lactoylglutathione lyase activity
BLMD_RS07060	COG1388	LysM domain
BLMD_RS07060	COG3584	3D domain protein
BLMD_RS07065	COG2814	Major facilitator Superfamily
BLMD_RS07070	COG1309	transcriptional regulator
BLMD_RS07090	COG5444	nuclease activity
BLMD_RS07095	COG4195	phage-related replication protein
BLMD_RS07100	COG2856	Zn peptidase
BLMD_RS07105	COG1396	sequence-specific DNA binding
BLMD_RS07120	COG1522	sequence-specific DNA binding
BLMD_RS07125	COG1484	DNA-dependent DNA replication
BLMD_RS07140	COG1595	DNA-templated transcription, initiation
BLMD_RS07145	COG3728	DNA packaging
BLMD_RS07145	COG5484	DNA packaging
BLMD_RS07150	COG1783	phage Terminase large subunit
BLMD_RS07155	COG5518	Phage portal protein
BLMD_RS07160	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BLMD_RS07165	COG4653	Phage capsid family
BLMD_RS07210	COG3953	SLT domain
BLMD_RS07210	COG5280	Phage tail tape measure protein TP901
BLMD_RS07215	COG1652	LysM domain
BLMD_RS07220	COG4193	domain, Protein
BLMD_RS07230	COG3628	GPW Gp25 family protein
BLMD_RS07235	COG3299	homolog of phage Mu protein gp47
BLMD_RS07240	COG3778	Protein conserved in bacteria
BLMD_RS07265	COG3594	Acyltransferase
BLMD_RS07275	COG1802	Transcriptional regulator
BLMD_RS07280	COG1063	alcohol dehydrogenase
BLMD_RS07285	COG1312	Catalyzes the dehydration of D-mannonate
BLMD_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS07295	COG1063	alcohol dehydrogenase
BLMD_RS07300	COG2271	Major facilitator Superfamily
BLMD_RS07315	COG0306	phosphate transporter
BLMD_RS07320	COG1392	Phosphate transport regulator
BLMD_RS07325	COG0405	Gamma-glutamyltransferase
BLMD_RS07330	COG5578	integral membrane protein
BLMD_RS07335	COG2972	Histidine kinase
BLMD_RS07340	COG4753	response regulator
BLMD_RS07340	COG2207	Transcriptional regulator
BLMD_RS07345	COG1653	transport
BLMD_RS07350	COG1175	transmembrane transport
BLMD_RS07355	COG0395	ABC-type sugar transport system, permease component
BLMD_RS07360	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLMD_RS07365	COG2207	Transcriptional regulator
BLMD_RS07370	COG2755	lipolytic protein G-D-S-L family
BLMD_RS07380	COG5578	integral membrane protein
BLMD_RS07385	COG3401	FG-GAP repeat protein
BLMD_RS07395	COG2755	lipolytic protein G-D-S-L family
BLMD_RS07400	COG3401	FG-GAP repeat protein
BLMD_RS07405	COG0667	Aldo Keto reductase
BLMD_RS07410	COG1874	Beta-galactosidase
BLMD_RS07420	COG1653	transport
BLMD_RS07425	COG4209	transmembrane transport
BLMD_RS07430	COG0395	ABC-type sugar transport system, permease component
BLMD_RS07435	COG0531	amino acid
BLMD_RS07440	COG0346	lactoylglutathione lyase activity
BLMD_RS07445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_RS07450	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_RS07460	COG2362	D-Aminopeptidase
BLMD_RS07465	COG0601	transmembrane transport
BLMD_RS07470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS07475	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS07480	COG4166	transmembrane transport
BLMD_RS07485	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLMD_RS07490	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_RS07495	COG0791	NLP P60 protein
BLMD_RS07500	COG4608	Belongs to the ABC transporter superfamily
BLMD_RS07510	COG1834	amidinotransferase
BLMD_RS07515	COG1607	acyl-coa hydrolase
BLMD_RS07520	COG2323	membrane
BLMD_RS07525	COG3866	Pectate lyase
BLMD_RS07545	COG2318	DinB family
BLMD_RS07550	COG2076	Multidrug Resistance protein
BLMD_RS07555	COG2076	Multidrug Resistance protein
BLMD_RS07560	COG0788	formyltetrahydrofolate deformylase activity
BLMD_RS07570	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLMD_RS07575	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLMD_RS07580	COG1764	response to oxidative stress
BLMD_RS07585	COG1846	Transcriptional regulator
BLMD_RS07590	COG1764	response to oxidative stress
BLMD_RS07600	COG0590	tRNA wobble adenosine to inosine editing
BLMD_RS07605	COG0406	alpha-ribazole phosphatase activity
BLMD_RS07620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLMD_RS07625	COG1404	Belongs to the peptidase S8 family
BLMD_RS07630	COG2239	Acts as a magnesium transporter
BLMD_RS07640	COG0789	Transcriptional regulator
BLMD_RS07650	COG1846	Transcriptional regulator
BLMD_RS07655	COG3285	dna ligase
BLMD_RS07655	COG1793	dna ligase
BLMD_RS07660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BLMD_RS07665	COG3300	MHYT domain
BLMD_RS07665	COG5001	Diguanylate cyclase
BLMD_RS07670	COG0586	Pfam SNARE associated Golgi protein
BLMD_RS07675	COG0861	Integral membrane protein TerC family
BLMD_RS07680	COG1191	sigma factor activity
BLMD_RS07700	COG0501	Belongs to the peptidase M48B family
BLMD_RS07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_RS07710	COG0768	penicillin binding
BLMD_RS07725	COG3594	Acyltransferase
BLMD_RS07730	COG5002	protein histidine kinase activity
BLMD_RS07735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLMD_RS07740	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BLMD_RS07745	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BLMD_RS07750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLMD_RS07755	COG0436	Aminotransferase
BLMD_RS07760	COG1850	ribulose-bisphosphate carboxylase activity
BLMD_RS07765	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLMD_RS07765	COG0235	Class ii aldolase
BLMD_RS07770	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BLMD_RS07770	COG0235	Class ii aldolase
BLMD_RS07775	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BLMD_RS07780	COG0346	lactoylglutathione lyase activity
BLMD_RS07785	COG3339	Conserved Protein
BLMD_RS07795	COG3852	Histidine kinase
BLMD_RS07800	COG1846	Transcriptional regulator
BLMD_RS07805	COG1360	Flagellar Motor Protein
BLMD_RS07810	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLMD_RS07815	COG0542	response to heat
BLMD_RS07820	COG3949	Membrane
BLMD_RS07825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLMD_RS07830	COG0720	synthase
BLMD_RS07835	COG0602	queuosine metabolic process
BLMD_RS07840	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BLMD_RS07850	COG0457	Tetratricopeptide repeat
BLMD_RS07855	COG3739	integral membrane protein
BLMD_RS07860	COG3655	Transcriptional regulator
BLMD_RS07895	COG4873	Protein conserved in bacteria
BLMD_RS07905	COG3773	Cell wall hydrolase
BLMD_RS07910	COG2244	polysaccharide biosynthetic process
BLMD_RS07915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS07920	COG2217	Heavy metal translocating P-type atpase
BLMD_RS07925	COG0006	proline dipeptidase activity
BLMD_RS07935	COG1609	Transcriptional regulator
BLMD_RS07940	COG3711	transcriptional antiterminator
BLMD_RS07945	COG1263	PTS System
BLMD_RS07945	COG2190	(PTS) system
BLMD_RS07945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS07950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS07955	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLMD_RS07965	COG1533	DNA photolyase activity
BLMD_RS07970	COG0456	acetyltransferase
BLMD_RS07975	COG0840	transmembrane signaling receptor activity
BLMD_RS07980	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS07985	COG2084	Dehydrogenase
BLMD_RS07990	COG2340	Cysteine-rich secretory protein family
BLMD_RS07995	COG0768	penicillin binding
BLMD_RS08000	COG4191	Histidine kinase
BLMD_RS08005	COG0436	Aminotransferase
BLMD_RS08010	COG1714	RDD family
BLMD_RS08020	COG0835	chemotaxis
BLMD_RS08020	COG0784	Response regulator, receiver
BLMD_RS08030	COG2814	Major facilitator Superfamily
BLMD_RS08035	COG1376	ErfK ybiS ycfS ynhG family protein
BLMD_RS08040	COG1408	metallophosphoesterase
BLMD_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS08050	COG2200	EAL domain
BLMD_RS08065	COG4703	Protein of unknown function (DUF1797)
BLMD_RS08070	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BLMD_RS08080	COG0517	IMP dehydrogenase activity
BLMD_RS08085	COG0583	DNA-binding transcription factor activity
BLMD_RS08090	COG0716	FMN binding
BLMD_RS08100	COG0716	FMN binding
BLMD_RS08105	COG2171	N-acyltransferase activity
BLMD_RS08110	COG1473	amidohydrolase
BLMD_RS08120	COG0450	alkyl hydroperoxide reductase
BLMD_RS08125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS08140	COG0746	molybdenum cofactor guanylyltransferase activity
BLMD_RS08145	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLMD_RS08150	COG0303	'Molybdopterin
BLMD_RS08155	COG1763	Mo-molybdopterin cofactor biosynthetic process
BLMD_RS08160	COG0314	molybdopterin synthase activity
BLMD_RS08165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BLMD_RS08175	COG1132	(ABC) transporter
BLMD_RS08180	COG1132	(ABC) transporter
BLMD_RS08190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLMD_RS08195	COG1136	(ABC) transporter
BLMD_RS08200	COG0577	efflux transmembrane transporter activity
BLMD_RS08210	COG1349	DNA-binding transcription factor activity
BLMD_RS08215	COG1105	Belongs to the carbohydrate kinase PfkB family
BLMD_RS08220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS08220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS08220	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS08240	COG0488	(ABC) transporter
BLMD_RS08250	COG2309	aminopeptidase activity
BLMD_RS08255	COG1077	Cell shape determining protein MreB Mrl
BLMD_RS08260	COG2002	toxin-antitoxin pair type II binding
BLMD_RS08265	COG3852	Histidine kinase
BLMD_RS08270	COG0569	domain protein
BLMD_RS08275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BLMD_RS08280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMD_RS08285	COG5503	Protein of unknown function (DUF1447)
BLMD_RS08295	COG0561	phosphatase activity
BLMD_RS08300	COG0242	peptide deformylase activity
BLMD_RS08310	COG0497	DNA recombination
BLMD_RS08315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_RS08320	COG0022	dehydrogenase e1 component
BLMD_RS08325	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_RS08330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_RS08335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS08345	COG1982	Orn Lys Arg decarboxylase major
BLMD_RS08350	COG4476	Belongs to the UPF0223 family
BLMD_RS08355	COG4493	Belongs to the UPF0637 family
BLMD_RS08365	COG0483	inositol monophosphate 1-phosphatase activity
BLMD_RS08385	COG1595	DNA-templated transcription, initiation
BLMD_RS08400	COG1217	gtp-binding protein TYPA
BLMD_RS08410	COG1846	Transcriptional regulator
BLMD_RS08415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BLMD_RS08420	COG4896	Protein conserved in bacteria
BLMD_RS08430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BLMD_RS08435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLMD_RS08440	COG2066	Belongs to the glutaminase family
BLMD_RS08445	COG4838	Belongs to the UPF0358 family
BLMD_RS08450	COG0772	Belongs to the SEDS family
BLMD_RS08455	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BLMD_RS08460	COG1612	heme a metabolic process
BLMD_RS08465	COG0109	protoheme IX farnesyltransferase activity
BLMD_RS08470	COG2010	Cytochrome c
BLMD_RS08470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLMD_RS08475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLMD_RS08480	COG1845	cytochrome c oxidase, subunit III
BLMD_RS08485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLMD_RS08490	COG3336	cytochrome c oxidase
BLMD_RS08500	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BLMD_RS08505	COG2340	Cysteine-rich secretory protein family
BLMD_RS08520	COG3679	Belongs to the UPF0342 family
BLMD_RS08525	COG4471	UPF0298 protein
BLMD_RS08530	COG0742	ribosomal rna small subunit methyltransferase
BLMD_RS08535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLMD_RS08540	COG3314	Sporulation integral membrane protein YlbJ
BLMD_RS08545	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLMD_RS08550	COG1323	Belongs to the UPF0348 family
BLMD_RS08555	COG1399	metal-binding, possibly nucleic acid-binding protein
BLMD_RS08560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLMD_RS08570	COG0454	-acetyltransferase
BLMD_RS08575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLMD_RS08580	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BLMD_RS08585	COG2001	Belongs to the MraZ family
BLMD_RS08590	COG0275	rRNA processing
BLMD_RS08595	COG4839	cell division protein FtsL
BLMD_RS08600	COG0768	penicillin binding
BLMD_RS08605	COG0768	penicillin binding
BLMD_RS08610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLMD_RS08615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLMD_RS08620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLMD_RS08625	COG0772	Belongs to the SEDS family
BLMD_RS08630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_RS08635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLMD_RS08640	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BLMD_RS08645	COG3879	Bacterial protein of unknown function (DUF881)
BLMD_RS08650	COG3879	Bacterial protein of unknown function (DUF881)
BLMD_RS08655	COG3856	small basic protein
BLMD_RS08660	COG0849	cell division
BLMD_RS08665	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLMD_RS08670	COG4412	M6 family metalloprotease domain protein
BLMD_RS08670	COG1404	Belongs to the peptidase S8 family
BLMD_RS08675	COG1404	Belongs to the peptidase S8 family
BLMD_RS08675	COG4412	M6 family metalloprotease domain protein
BLMD_RS08685	COG1191	sigma factor activity
BLMD_RS08690	COG1191	sigma factor activity
BLMD_RS08695	COG1119	ATPase activity
BLMD_RS08700	COG0500	methyltransferase
BLMD_RS08705	COG1873	PFAM PRC-barrel domain
BLMD_RS08710	COG1496	oxidoreductase activity
BLMD_RS08715	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLMD_RS08720	COG1799	cell septum assembly
BLMD_RS08725	COG0762	integral membrane protein
BLMD_RS08730	COG2302	S4 RNA-binding domain
BLMD_RS08735	COG3599	regulation of cell shape
BLMD_RS08740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLMD_RS08745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_RS08750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLMD_RS08755	COG0564	pseudouridine synthase activity
BLMD_RS08765	COG2233	PERMEase
BLMD_RS08770	COG0540	Belongs to the ATCase OTCase family
BLMD_RS08775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLMD_RS08780	COG0505	Belongs to the CarA family
BLMD_RS08785	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLMD_RS08790	COG0543	2 iron, 2 sulfur cluster binding
BLMD_RS08795	COG0167	dihydroorotate dehydrogenase activity
BLMD_RS08800	COG0284	orotidine-5'-phosphate decarboxylase activity
BLMD_RS08805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLMD_RS08815	COG0175	sulfate reduction
BLMD_RS08820	COG0306	phosphate transporter
BLMD_RS08825	COG2046	Belongs to the sulfate adenylyltransferase family
BLMD_RS08830	COG0529	Catalyzes the synthesis of activated sulfate
BLMD_RS08835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLMD_RS08840	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BLMD_RS08845	COG1648	precorrin-2 dehydrogenase activity
BLMD_RS08855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLMD_RS08860	COG1561	YicC-like family, N-terminal region
BLMD_RS08865	COG2052	Domain of unknown function (DUF370)
BLMD_RS08870	COG0194	GDP metabolic process
BLMD_RS08875	COG1758	RNA polymerase activity
BLMD_RS08880	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLMD_RS08885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLMD_RS08890	COG0242	peptide deformylase activity
BLMD_RS08895	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLMD_RS08900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLMD_RS08900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLMD_RS08905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BLMD_RS08910	COG0631	protein serine/threonine phosphatase activity
BLMD_RS08915	COG2815	serine threonine protein kinase
BLMD_RS08915	COG0515	serine threonine protein kinase
BLMD_RS08920	COG1162	GTPase activity
BLMD_RS08925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLMD_RS08930	COG1564	THIamine pyrophosphokinase
BLMD_RS08940	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLMD_RS08945	COG1302	Protein conserved in bacteria
BLMD_RS08950	COG1461	Dihydroxyacetone kinase
BLMD_RS08955	COG1760	l-serine dehydratase
BLMD_RS08960	COG1760	l-serine dehydratase
BLMD_RS08965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLMD_RS08970	COG1349	DNA-binding transcription factor activity
BLMD_RS08975	COG0416	fatty acid biosynthetic process
BLMD_RS08980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLMD_RS08985	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS08990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLMD_RS08995	COG0571	ribonuclease III activity
BLMD_RS09000	COG1196	nuclear chromosome segregation
BLMD_RS09005	COG0552	protein localization to endoplasmic reticulum
BLMD_RS09010	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BLMD_RS09015	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLMD_RS09020	COG0228	four-way junction DNA binding
BLMD_RS09025	COG1837	Belongs to the UPF0109 family
BLMD_RS09035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLMD_RS09040	COG0336	Belongs to the RNA methyltransferase TrmD family
BLMD_RS09045	COG0335	large ribosomal subunit rRNA binding
BLMD_RS09050	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLMD_RS09055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLMD_RS09065	COG2257	FlhB HrpN YscU SpaS Family
BLMD_RS09070	COG0045	succinate-CoA ligase (ADP-forming) activity
BLMD_RS09075	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLMD_RS09080	COG0758	DNA mediated transformation
BLMD_RS09085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLMD_RS09090	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLMD_RS09095	COG4974	Belongs to the 'phage' integrase family
BLMD_RS09100	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLMD_RS09105	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLMD_RS09110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLMD_RS09115	COG1815	bacterial-type flagellum-dependent cell motility
BLMD_RS09120	COG1558	bacterial-type flagellum-dependent cell motility
BLMD_RS09125	COG1677	Flagellar hook-basal body complex protein FliE
BLMD_RS09130	COG1766	The M ring may be actively involved in energy transduction
BLMD_RS09135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_RS09140	COG1317	bacterial-type flagellum organization
BLMD_RS09145	COG1157	protein secretion by the type III secretion system
BLMD_RS09150	COG2882	bacterial-type flagellum organization
BLMD_RS09155	COG3334	PFAM MgtE intracellular
BLMD_RS09160	COG3144	bacterial-type flagellum assembly
BLMD_RS09165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BLMD_RS09170	COG4786	Flagellar basal body rod
BLMD_RS09175	COG1582	Flagellar protein (FlbD)
BLMD_RS09180	COG1580	Controls the rotational direction of flagella during chemotaxis
BLMD_RS09185	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_RS09190	COG1776	CheC inhibitor of MCP methylation
BLMD_RS09190	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLMD_RS09195	COG2201	protein-glutamate methylesterase activity
BLMD_RS09200	COG3190	flagellar
BLMD_RS09205	COG1338	Plays a role in the flagellum-specific transport system
BLMD_RS09210	COG1987	bacterial-type flagellum assembly
BLMD_RS09215	COG1684	flagellar biosynthetic protein fliR
BLMD_RS09220	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLMD_RS09225	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLMD_RS09230	COG1419	protein localization to endoplasmic reticulum
BLMD_RS09235	COG0455	bacterial-type flagellum organization
BLMD_RS09240	COG2201	protein-glutamate methylesterase activity
BLMD_RS09245	COG0643	Histidine kinase
BLMD_RS09245	COG2198	Histidine kinase
BLMD_RS09250	COG0835	chemotaxis
BLMD_RS09255	COG1776	CheC inhibitor of MCP methylation
BLMD_RS09260	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BLMD_RS09265	COG1191	sigma factor activity
BLMD_RS09275	COG0052	Belongs to the universal ribosomal protein uS2 family
BLMD_RS09280	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLMD_RS09285	COG0528	UMP kinase activity
BLMD_RS09290	COG0233	cytoplasmic translational termination
BLMD_RS09295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLMD_RS09300	COG4589	Belongs to the CDS family
BLMD_RS09305	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BLMD_RS09310	COG0750	zinc metalloprotease
BLMD_RS09315	COG0442	prolyl-tRNA aminoacylation
BLMD_RS09320	COG2176	DNA-directed DNA polymerase activity
BLMD_RS09345	COG0779	Required for maturation of 30S ribosomal subunits
BLMD_RS09350	COG0195	Participates in both transcription termination and antitermination
BLMD_RS09355	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BLMD_RS09360	COG1358	cellular component organization or biogenesis
BLMD_RS09365	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLMD_RS09370	COG1550	Protein conserved in bacteria
BLMD_RS09375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BLMD_RS09380	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLMD_RS09385	COG0196	riboflavin kinase activity
BLMD_RS09390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLMD_RS09395	COG1185	polyribonucleotide nucleotidyltransferase activity
BLMD_RS09400	COG0726	polysaccharide deacetylase
BLMD_RS09405	COG0612	Peptidase, M16
BLMD_RS09410	COG1873	PFAM PRC-barrel domain
BLMD_RS09415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_RS09420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLMD_RS09425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLMD_RS09430	COG0527	aspartate kinase activity
BLMD_RS09440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLMD_RS09445	COG0740	serine-type endopeptidase activity
BLMD_RS09455	COG1674	ftsk spoiiie
BLMD_RS09455	COG4980	gas vesicle protein
BLMD_RS09460	COG2188	Transcriptional regulator
BLMD_RS09465	COG2814	Major facilitator Superfamily
BLMD_RS09470	COG0612	Peptidase, M16
BLMD_RS09475	COG0612	Peptidase, M16
BLMD_RS09480	COG0300	oxidoreductase activity
BLMD_RS09495	COG1426	Protein conserved in bacteria
BLMD_RS09500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLMD_RS09505	COG1058	Belongs to the CinA family
BLMD_RS09505	COG1546	Belongs to the CinA family
BLMD_RS09515	COG1418	mRNA catabolic process
BLMD_RS09520	COG1692	metallophosphoesterase
BLMD_RS09525	COG2359	stage V sporulation protein S
BLMD_RS09535	COG1063	alcohol dehydrogenase
BLMD_RS09545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLMD_RS09550	COG4550	Control of competence regulator ComK, YlbF/YmcA
BLMD_RS09560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLMD_RS09565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLMD_RS09570	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BLMD_RS09595	COG0457	Tetratricopeptide repeat
BLMD_RS09600	COG5444	nuclease activity
BLMD_RS09610	COG0523	cobalamin synthesis protein
BLMD_RS09635	COG3619	membrane
BLMD_RS09640	COG3263	regulation of cellular component size
BLMD_RS09645	COG2814	Major facilitator Superfamily
BLMD_RS09655	COG0393	Putative heavy-metal-binding
BLMD_RS09660	COG0398	Pfam SNARE associated Golgi protein
BLMD_RS09665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BLMD_RS09670	COG1819	glycosyl
BLMD_RS09675	COG0531	amino acid
BLMD_RS09680	COG5577	PFAM Coat F domain
BLMD_RS09690	COG3858	chitin binding
BLMD_RS09690	COG1388	LysM domain
BLMD_RS09695	COG1309	transcriptional regulator
BLMD_RS09700	COG3631	Ketosteroid isomerase-related protein
BLMD_RS09705	COG0702	epimerase
BLMD_RS09715	COG1764	response to oxidative stress
BLMD_RS09720	COG2076	Multidrug Resistance protein
BLMD_RS09725	COG2076	Multidrug Resistance protein
BLMD_RS09740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLMD_RS09745	COG1923	regulation of RNA biosynthetic process
BLMD_RS09760	COG1780	Probably involved in ribonucleotide reductase function
BLMD_RS09765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLMD_RS09770	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLMD_RS09775	COG4112	unkown
BLMD_RS09790	COG0735	belongs to the Fur family
BLMD_RS09795	COG1802	Transcriptional regulator
BLMD_RS09800	COG0697	spore germination
BLMD_RS09840	COG1309	transcriptional regulator
BLMD_RS09875	COG4282	regulation of fungal-type cell wall biogenesis
BLMD_RS09880	COG5444	nuclease activity
BLMD_RS09905	COG2814	Major facilitator Superfamily
BLMD_RS09910	COG0457	Tetratricopeptide repeat
BLMD_RS09920	COG4413	Urea transporter
BLMD_RS09930	COG0832	Belongs to the urease beta subunit family
BLMD_RS09940	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BLMD_RS09945	COG0830	nickel cation binding
BLMD_RS09950	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BLMD_RS09955	COG0829	nickel cation binding
BLMD_RS09965	COG1695	Transcriptional regulator
BLMD_RS09985	COG0464	growth
BLMD_RS09990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLMD_RS09995	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BLMD_RS10000	COG0789	Transcriptional regulator
BLMD_RS10005	COG0174	glutamine synthetase
BLMD_RS10035	COG0174	glutamine synthetase
BLMD_RS10065	COG0490	domain, Protein
BLMD_RS10070	COG0475	glutathione-regulated potassium exporter activity
BLMD_RS10080	COG1073	alpha beta
BLMD_RS10120	COG1309	transcriptional regulator
BLMD_RS10125	COG2076	Multidrug Resistance protein
BLMD_RS10130	COG2076	Multidrug Resistance protein
BLMD_RS10135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_RS10155	COG3546	catalase activity
BLMD_RS10180	COG1846	Transcriptional regulator
BLMD_RS10185	COG0346	lactoylglutathione lyase activity
BLMD_RS10190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLMD_RS10195	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS10220	COG3209	COG3209 Rhs family protein
BLMD_RS10230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLMD_RS10235	COG1388	LysM domain
BLMD_RS10240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLMD_RS10245	COG4224	UPF0291 protein
BLMD_RS10250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLMD_RS10260	COG3763	UPF0154 protein
BLMD_RS10270	COG0785	Cytochrome C biogenesis protein
BLMD_RS10275	COG2201	protein-glutamate methylesterase activity
BLMD_RS10280	COG4846	Membrane protein involved in cytochrome C biogenesis
BLMD_RS10290	COG0071	Belongs to the small heat shock protein (HSP20) family
BLMD_RS10305	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLMD_RS10310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS10330	COG0824	Thioesterase
BLMD_RS10350	COG4841	protein insertion into membrane
BLMD_RS10355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BLMD_RS10360	COG1832	CoA-binding protein
BLMD_RS10365	COG0187	DNA topoisomerase II activity
BLMD_RS10370	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLMD_RS10375	COG1609	Transcriptional regulator
BLMD_RS10390	COG2160	L-arabinose isomerase activity
BLMD_RS10410	COG1115	amino acid carrier protein
BLMD_RS10420	COG2181	nitrate reductase activity
BLMD_RS10425	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BLMD_RS10430	COG1140	nitrate reductase beta subunit
BLMD_RS10435	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BLMD_RS10450	COG0535	radical SAM domain protein
BLMD_RS10455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLMD_RS10465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLMD_RS10470	COG2223	nitrite transmembrane transporter activity
BLMD_RS10490	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BLMD_RS10500	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BLMD_RS10530	COG0477	Major facilitator Superfamily
BLMD_RS10535	COG3420	alginic acid biosynthetic process
BLMD_RS10540	COG1114	Component of the transport system for branched-chain amino acids
BLMD_RS10550	COG1687	branched-chain amino acid
BLMD_RS10555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BLMD_RS10560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS10590	COG1024	Enoyl-CoA hydratase
BLMD_RS10595	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS10600	COG2084	Dehydrogenase
BLMD_RS10605	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS10610	COG1482	cell wall glycoprotein biosynthetic process
BLMD_RS10615	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS10615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS10615	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS10625	COG0582	viral genome integration into host DNA
BLMD_RS10645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS10645	COG3711	transcriptional antiterminator
BLMD_RS10660	COG1725	Transcriptional regulator
BLMD_RS10665	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS10670	COG1312	Catalyzes the dehydration of D-mannonate
BLMD_RS10685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BLMD_RS10695	COG1609	Transcriptional regulator
BLMD_RS10700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_RS10705	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLMD_RS10710	COG0640	Transcriptional regulator
BLMD_RS10715	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BLMD_RS10730	COG1649	PFAM Uncharacterised BCR, COG1649
BLMD_RS10735	COG2404	hydrolase activity, acting on ester bonds
BLMD_RS10740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLMD_RS10750	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS10755	COG2027	D-alanyl-D-alanine carboxypeptidase
BLMD_RS10775	COG1309	transcriptional regulator
BLMD_RS10780	COG1252	NADH dehydrogenase
BLMD_RS10795	COG0166	Belongs to the GPI family
BLMD_RS10805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_RS10810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLMD_RS10815	COG1024	Enoyl-CoA hydratase
BLMD_RS10820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLMD_RS10825	COG0511	ligase activity, forming carbon-carbon bonds
BLMD_RS10830	COG0439	Biotin carboxylase
BLMD_RS10835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BLMD_RS10835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS10840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS10845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS10850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS10855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS10860	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS10865	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS10870	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS10875	COG1733	regulation of RNA biosynthetic process
BLMD_RS10880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BLMD_RS10885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLMD_RS10895	COG2323	membrane
BLMD_RS10900	COG0306	phosphate transporter
BLMD_RS10905	COG0175	sulfate reduction
BLMD_RS10910	COG1809	phosphosulfolactate synthase activity
BLMD_RS10915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS10920	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_RS10925	COG2814	Major facilitator Superfamily
BLMD_RS10930	COG0463	Glycosyl transferase, family 2
BLMD_RS10945	COG0493	'glutamate synthase
BLMD_RS10950	COG0070	glutamate synthase
BLMD_RS10950	COG0069	glutamate synthase activity
BLMD_RS10950	COG0067	glutamate synthase
BLMD_RS10955	COG0583	DNA-binding transcription factor activity
BLMD_RS10980	COG1132	(ABC) transporter
BLMD_RS10990	COG0300	oxidoreductase activity
BLMD_RS10995	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_RS10995	COG3848	Pyruvate phosphate dikinase
BLMD_RS11000	COG0477	Major facilitator Superfamily
BLMD_RS11005	COG0243	molybdopterin cofactor binding
BLMD_RS11010	COG1846	Transcriptional regulator
BLMD_RS11015	COG2814	Major facilitator Superfamily
BLMD_RS11020	COG0531	amino acid
BLMD_RS11030	COG0531	amino acid
BLMD_RS11035	COG0531	amino acid
BLMD_RS11040	COG0697	spore germination
BLMD_RS11045	COG0488	(ABC) transporter
BLMD_RS11050	COG0840	transmembrane signaling receptor activity
BLMD_RS11055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_RS11060	COG1404	Belongs to the peptidase S8 family
BLMD_RS11070	COG1309	transcriptional regulator
BLMD_RS11075	COG1846	Transcriptional regulator
BLMD_RS11105	COG1309	transcriptional regulator
BLMD_RS11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS11115	COG3708	Transcriptional regulator
BLMD_RS11125	COG2378	regulation of single-species biofilm formation
BLMD_RS11135	COG0640	Transcriptional regulator
BLMD_RS11140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS11150	COG0531	amino acid
BLMD_RS11155	COG0741	lytic transglycosylase activity
BLMD_RS11160	COG1086	Polysaccharide biosynthesis protein
BLMD_RS11175	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS11180	COG2322	membrane
BLMD_RS11195	COG1619	proteins homologs of microcin C7 resistance protein MccF
BLMD_RS11200	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS11205	COG3584	3D domain protein
BLMD_RS11205	COG1388	LysM domain
BLMD_RS11210	COG0514	ATP-dependent DNA helicase (RecQ)
BLMD_RS11230	COG2315	Protein conserved in bacteria
BLMD_RS11235	COG5444	nuclease activity
BLMD_RS11240	COG2427	Protein of unknown function (DUF1641)
BLMD_RS11245	COG3383	formate dehydrogenase (NAD+) activity
BLMD_RS11260	COG5444	nuclease activity
BLMD_RS11270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_RS11285	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BLMD_RS11290	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BLMD_RS11320	COG2350	Protein conserved in bacteria
BLMD_RS11345	COG0402	S-adenosylhomocysteine deaminase activity
BLMD_RS11360	COG2267	carboxylic ester hydrolase activity
BLMD_RS11375	COG1280	lysine exporter protein (LysE YggA)
BLMD_RS11385	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLMD_RS11395	COG3848	Pyruvate phosphate dikinase
BLMD_RS11395	COG0574	Belongs to the PEP-utilizing enzyme family
BLMD_RS11415	COG2318	DinB family
BLMD_RS11420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLMD_RS11440	COG0156	8-amino-7-oxononanoate synthase activity
BLMD_RS11445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_RS11460	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS11480	COG1657	PFAM Prenyltransferase squalene oxidase
BLMD_RS11485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLMD_RS11495	COG0733	neurotransmitter:sodium symporter activity
BLMD_RS11500	COG0385	Bile acid
BLMD_RS11505	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_RS11510	COG0567	Dehydrogenase, E1 component
BLMD_RS11515	COG4548	von Willebrand factor, type A
BLMD_RS11520	COG0714	Associated with various cellular activities
BLMD_RS11525	COG2032	superoxide dismutase activity
BLMD_RS11530	COG1388	LysM domain
BLMD_RS11530	COG0791	NLP P60 protein
BLMD_RS11540	COG0534	Mate efflux family protein
BLMD_RS11545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_RS11550	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_RS11560	COG2962	Rard protein
BLMD_RS11570	COG4305	rare lipoprotein A
BLMD_RS11585	COG1733	regulation of RNA biosynthetic process
BLMD_RS11590	COG0778	Nitroreductase
BLMD_RS11595	COG0400	carboxylic ester hydrolase activity
BLMD_RS11605	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS11610	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_RS11610	COG0793	Belongs to the peptidase S41A family
BLMD_RS11615	COG2226	methyltransferase
BLMD_RS11625	COG1876	peptidase activity
BLMD_RS11630	COG0813	purine-nucleoside phosphorylase activity
BLMD_RS11635	COG0701	Predicted permease
BLMD_RS11650	COG0671	phosphoesterase, PA-phosphatase related
BLMD_RS11665	COG4479	Belongs to the UPF0346 family
BLMD_RS11675	COG1509	lysine 2,3-aminomutase activity
BLMD_RS11680	COG0456	acetyltransferase
BLMD_RS11685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_RS11690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BLMD_RS11695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BLMD_RS11700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLMD_RS11715	COG0456	acetyltransferase
BLMD_RS11730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLMD_RS11735	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLMD_RS11740	COG1846	Transcriptional regulator
BLMD_RS11750	COG3706	GGDEF domain
BLMD_RS11755	COG0534	Mate efflux family protein
BLMD_RS11770	COG4698	Protein conserved in bacteria
BLMD_RS11775	COG2755	lipolytic protein G-D-S-L family
BLMD_RS11780	COG1999	signal sequence binding
BLMD_RS11800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLMD_RS11805	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLMD_RS11810	COG1272	protein, Hemolysin III
BLMD_RS11815	COG0204	Acyl-transferase
BLMD_RS11820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLMD_RS11830	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLMD_RS11840	COG2521	methyltransferase
BLMD_RS11840	COG2136	Putative SAM-dependent methyltransferase
BLMD_RS11850	COG0129	dihydroxy-acid dehydratase activity
BLMD_RS11855	COG1413	lyase activity
BLMD_RS11865	COG0386	Belongs to the glutathione peroxidase family
BLMD_RS11870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BLMD_RS11875	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BLMD_RS11880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_RS11890	COG1278	Cold shock
BLMD_RS11910	COG0328	RNA-DNA hybrid ribonuclease activity
BLMD_RS11915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BLMD_RS11920	COG0328	RNA-DNA hybrid ribonuclease activity
BLMD_RS11930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_RS11940	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLMD_RS11950	COG1755	Isoprenylcysteine carboxyl methyltransferase
BLMD_RS11955	COG3424	synthase
BLMD_RS11965	COG2233	PERMEase
BLMD_RS11970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_RS11975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BLMD_RS11980	COG1199	ATP-dependent helicase activity
BLMD_RS12000	COG0116	Belongs to the methyltransferase superfamily
BLMD_RS12010	COG3599	regulation of cell shape
BLMD_RS12015	COG4474	Belongs to the UPF0398 family
BLMD_RS12025	COG3359	exonuclease
BLMD_RS12030	COG1111	helicase
BLMD_RS12030	COG1205	dead DEAH box helicase
BLMD_RS12035	COG2190	(PTS) system
BLMD_RS12040	COG0071	Belongs to the small heat shock protein (HSP20) family
BLMD_RS12075	COG3331	DNA recombination
BLMD_RS12080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_RS12080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLMD_RS12090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLMD_RS12095	COG3935	DnaD domain protein
BLMD_RS12100	COG0017	Asparaginyl-tRNA synthetase
BLMD_RS12105	COG0436	Aminotransferase
BLMD_RS12110	COG5353	protein conserved in bacteria
BLMD_RS12120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLMD_RS12120	COG1199	ATP-dependent helicase activity
BLMD_RS12125	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BLMD_RS12130	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BLMD_RS12135	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BLMD_RS12145	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BLMD_RS12145	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BLMD_RS12150	COG0617	tRNA 3'-terminal CCA addition
BLMD_RS12155	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS12160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BLMD_RS12165	COG1803	Methylglyoxal synthase
BLMD_RS12170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLMD_RS12175	COG1694	Mazg nucleotide pyrophosphohydrolase
BLMD_RS12180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS12190	COG4347	Protein of unknown function (DUF1405)
BLMD_RS12195	COG2010	Cytochrome c
BLMD_RS12195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLMD_RS12200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BLMD_RS12205	COG0723	plastoquinol--plastocyanin reductase activity
BLMD_RS12215	COG5582	Belongs to the UPF0302 family
BLMD_RS12220	COG0457	Tetratricopeptide repeat
BLMD_RS12225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BLMD_RS12230	COG0287	Prephenate dehydrogenase
BLMD_RS12235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLMD_RS12240	COG0159	tryptophan synthase activity
BLMD_RS12245	COG0133	tryptophan synthase activity
BLMD_RS12250	COG0135	phosphoribosylanthranilate isomerase activity
BLMD_RS12255	COG0134	indole-3-glycerol-phosphate synthase activity
BLMD_RS12260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLMD_RS12265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLMD_RS12270	COG4401	Chorismate mutase type I
BLMD_RS12275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLMD_RS12280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLMD_RS12285	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLMD_RS12290	COG0105	UTP biosynthetic process
BLMD_RS12295	COG0142	geranyltranstransferase activity
BLMD_RS12300	COG2226	methyltransferase
BLMD_RS12305	COG0142	geranyltranstransferase activity
BLMD_RS12320	COG0776	regulation of translation
BLMD_RS12325	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BLMD_RS12345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BLMD_RS12350	COG1160	GTP binding
BLMD_RS12375	COG1304	FMN binding
BLMD_RS12380	COG0539	negative regulation of cytoplasmic translation
BLMD_RS12385	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLMD_RS12390	COG2959	enzyme of heme biosynthesis
BLMD_RS12395	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_RS12395	COG3773	Cell wall hydrolase
BLMD_RS12400	COG2339	peptidase activity
BLMD_RS12410	COG0492	ferredoxin-NADP+ reductase activity
BLMD_RS12415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLMD_RS12420	COG4862	establishment of competence for transformation
BLMD_RS12425	COG1408	metallophosphoesterase
BLMD_RS12435	COG1388	LysM domain
BLMD_RS12440	COG1266	CAAX protease self-immunity
BLMD_RS12445	COG0514	ATP-dependent DNA helicase (RecQ)
BLMD_RS12450	COG4955	Helix-turn-helix domain
BLMD_RS12455	COG1141	Ferredoxin
BLMD_RS12460	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BLMD_RS12465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLMD_RS12470	COG0739	heme binding
BLMD_RS12480	COG1595	DNA-templated transcription, initiation
BLMD_RS12485	COG1316	TRANSCRIPTIONal
BLMD_RS12500	COG5002	protein histidine kinase activity
BLMD_RS12505	COG0745	RESPONSE REGULATOR receiver
BLMD_RS12510	COG5002	protein histidine kinase activity
BLMD_RS12515	COG0745	RESPONSE REGULATOR receiver
BLMD_RS12520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLMD_RS12525	COG1333	cytochrome c biogenesis protein
BLMD_RS12530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS12535	COG1187	pseudouridine synthase activity
BLMD_RS12540	COG0700	Nucleoside recognition
BLMD_RS12545	COG2715	membrane protein required for spore maturation
BLMD_RS12550	COG1686	Belongs to the peptidase S11 family
BLMD_RS12560	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLMD_RS12565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLMD_RS12575	COG1547	Domain of unknown function (DUF309)
BLMD_RS12580	COG0456	acetyltransferase
BLMD_RS12585	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLMD_RS12590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLMD_RS12590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLMD_RS12595	COG0307	riboflavin synthase, alpha
BLMD_RS12600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLMD_RS12600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLMD_RS12620	COG0457	Tetratricopeptide repeat
BLMD_RS12625	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLMD_RS12635	COG4086	secreted protein
BLMD_RS12640	COG4195	phage-related replication protein
BLMD_RS12650	COG0019	diaminopimelate decarboxylase activity
BLMD_RS12660	COG0697	spore germination
BLMD_RS12675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLMD_RS12700	COG2172	sigma factor antagonist activity
BLMD_RS12710	COG1686	Belongs to the peptidase S11 family
BLMD_RS12715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLMD_RS12720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BLMD_RS12725	COG4974	Belongs to the 'phage' integrase family
BLMD_RS12735	COG0735	belongs to the Fur family
BLMD_RS12740	COG1300	Membrane
BLMD_RS12745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS12755	COG1953	Uracil, thiamine, allantoin
BLMD_RS12775	COG2153	protein acetylation
BLMD_RS12780	COG1379	DNA repair
BLMD_RS12785	COG0494	nUDIX hydrolase
BLMD_RS12795	COG1309	transcriptional regulator
BLMD_RS12805	COG0667	Aldo Keto reductase
BLMD_RS12815	COG1073	alpha beta
BLMD_RS12825	COG4918	Iron-sulphur cluster biosynthesis
BLMD_RS12835	COG0456	acetyltransferase
BLMD_RS12835	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLMD_RS12840	COG2329	Antibiotic biosynthesis monooxygenase
BLMD_RS12845	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BLMD_RS12855	COG0747	negative chemotaxis
BLMD_RS12860	COG0601	transmembrane transport
BLMD_RS12865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS12870	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS12880	COG0534	Mate efflux family protein
BLMD_RS12895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLMD_RS12905	COG2211	Major facilitator Superfamily
BLMD_RS12910	COG0346	lactoylglutathione lyase activity
BLMD_RS12915	COG1072	(Pantothenic acid kinase))
BLMD_RS12925	COG3842	ATPase activity
BLMD_RS12950	COG2205	protein histidine kinase activity
BLMD_RS12955	COG0745	RESPONSE REGULATOR receiver
BLMD_RS12975	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BLMD_RS12980	COG2814	Major facilitator Superfamily
BLMD_RS12990	COG4195	phage-related replication protein
BLMD_RS13005	COG0457	Tetratricopeptide repeat
BLMD_RS13025	COG5444	nuclease activity
BLMD_RS13030	COG0300	oxidoreductase activity
BLMD_RS13035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS13040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_RS13045	COG4187	Peptidase family M20/M25/M40
BLMD_RS13050	COG1902	pentaerythritol trinitrate reductase activity
BLMD_RS13055	COG0596	Alpha beta hydrolase
BLMD_RS13060	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLMD_RS13065	COG1234	tRNA 3'-trailer cleavage
BLMD_RS13070	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BLMD_RS13085	COG2358	TRAP transporter, solute receptor (TAXI family
BLMD_RS13090	COG2188	Transcriptional regulator
BLMD_RS13095	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS13100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS13105	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_RS13110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS13115	COG1785	Belongs to the alkaline phosphatase family
BLMD_RS13120	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS13125	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLMD_RS13130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLMD_RS13140	COG0706	membrane insertase activity
BLMD_RS13145	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLMD_RS13150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLMD_RS13155	COG4129	membrane
BLMD_RS13160	COG1126	abc transporter atp-binding protein
BLMD_RS13165	COG0765	amino acid transport
BLMD_RS13170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLMD_RS13180	COG1597	lipid kinase activity
BLMD_RS13185	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLMD_RS13190	COG0022	dehydrogenase e1 component
BLMD_RS13195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLMD_RS13200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLMD_RS13205	COG3426	butyrate kinase activity
BLMD_RS13215	COG0280	phosphate acetyltransferase
BLMD_RS13220	COG3290	protein histidine kinase activity
BLMD_RS13220	COG3829	transcription factor binding
BLMD_RS13230	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_RS13235	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_RS13250	COG0745	RESPONSE REGULATOR receiver
BLMD_RS13255	COG0750	zinc metalloprotease
BLMD_RS13260	COG0497	DNA recombination
BLMD_RS13265	COG1438	arginine binding
BLMD_RS13270	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BLMD_RS13275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLMD_RS13280	COG0142	geranyltranstransferase activity
BLMD_RS13285	COG1722	exodeoxyribonuclease VII activity
BLMD_RS13290	COG1570	exodeoxyribonuclease VII activity
BLMD_RS13295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLMD_RS13300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLMD_RS13305	COG1302	Protein conserved in bacteria
BLMD_RS13310	COG0439	Biotin carboxylase
BLMD_RS13315	COG0511	ligase activity, forming carbon-carbon bonds
BLMD_RS13355	COG3854	ATPases associated with a variety of cellular activities
BLMD_RS13365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLMD_RS13370	COG0006	proline dipeptidase activity
BLMD_RS13375	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLMD_RS13385	COG3872	metal-dependent enzyme
BLMD_RS13395	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLMD_RS13400	COG1321	iron dependent repressor
BLMD_RS13405	COG0095	Lipoate-protein ligase
BLMD_RS13410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_RS13415	COG2113	Glycine betaine
BLMD_RS13420	COG4176	ABC-type proline glycine betaine transport system permease component
BLMD_RS13425	COG0517	IMP dehydrogenase activity
BLMD_RS13425	COG4175	Glycine betaine
BLMD_RS13430	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLMD_RS13435	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLMD_RS13440	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLMD_RS13450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLMD_RS13475	COG0681	Belongs to the peptidase S26 family
BLMD_RS13500	COG4940	Competence protein ComGF
BLMD_RS13510	COG4970	Tfp pilus assembly protein FimT
BLMD_RS13515	COG4537	Required for transformation and DNA binding
BLMD_RS13520	COG1459	type II secretion system
BLMD_RS13525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLMD_RS13530	COG1366	Belongs to the anti-sigma-factor antagonist family
BLMD_RS13540	COG1393	Belongs to the ArsC family
BLMD_RS13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS13560	COG0011	TIGRFAM Protein of
BLMD_RS13570	COG2866	Carboxypeptidase
BLMD_RS13575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS13580	COG1368	sulfuric ester hydrolase activity
BLMD_RS13585	COG1940	carbohydrate kinase activity
BLMD_RS13590	COG4483	Protein conserved in bacteria
BLMD_RS13595	COG0697	spore germination
BLMD_RS13600	COG0457	Tetratricopeptide repeat
BLMD_RS13600	COG0705	Rhomboid family
BLMD_RS13605	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLMD_RS13610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLMD_RS13615	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS13630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLMD_RS13635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLMD_RS13640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLMD_RS13645	COG0581	inorganic phosphate transmembrane transporter activity
BLMD_RS13650	COG0573	inorganic phosphate transmembrane transporter activity
BLMD_RS13655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BLMD_RS13660	COG0768	penicillin binding
BLMD_RS13665	COG0477	Major facilitator Superfamily
BLMD_RS13675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLMD_RS13680	COG2839	Protein conserved in bacteria
BLMD_RS13685	COG5521	maltodextrose utilization protein MalA
BLMD_RS13690	COG1388	LysM domain
BLMD_RS13695	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BLMD_RS13700	COG4709	membrane
BLMD_RS13705	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BLMD_RS13710	COG0735	belongs to the Fur family
BLMD_RS13715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLMD_RS13720	COG1121	(ABC) transporter
BLMD_RS13725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS13735	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BLMD_RS13740	COG0513	Belongs to the DEAD box helicase family
BLMD_RS13750	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLMD_RS13755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLMD_RS13760	COG2384	SAM-dependent methyltransferase
BLMD_RS13785	COG5444	nuclease activity
BLMD_RS13800	COG2010	Cytochrome c
BLMD_RS13805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLMD_RS13810	COG0358	DNA primase activity
BLMD_RS13815	COG1671	Belongs to the UPF0178 family
BLMD_RS13820	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BLMD_RS13825	COG0517	IMP dehydrogenase activity
BLMD_RS13830	COG0751	glycine-tRNA ligase activity
BLMD_RS13835	COG0752	glycyl-tRNA synthetase alpha subunit
BLMD_RS13840	COG1381	Involved in DNA repair and RecF pathway recombination
BLMD_RS13850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLMD_RS13855	COG0295	cytidine deaminase activity
BLMD_RS13860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BLMD_RS13865	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLMD_RS13870	COG1480	7TM receptor with intracellular HD hydrolase
BLMD_RS13875	COG1702	phosphate starvation-inducible protein PhoH
BLMD_RS13880	COG0561	phosphatase activity
BLMD_RS13895	COG4864	UPF0365 protein
BLMD_RS13900	COG1030	water channel activity
BLMD_RS13905	COG1610	YqeY-like protein
BLMD_RS13910	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLMD_RS13915	COG1283	sodium-dependent phosphate transmembrane transporter activity
BLMD_RS13920	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLMD_RS13925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLMD_RS13930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLMD_RS13935	COG2264	protein methyltransferase activity
BLMD_RS13940	COG0484	heat shock protein binding
BLMD_RS13945	COG0443	Heat shock 70 kDa protein
BLMD_RS13950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLMD_RS13955	COG1420	regulation of RNA biosynthetic process
BLMD_RS13960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLMD_RS13965	COG0481	GTPase activity
BLMD_RS13975	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_RS13980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BLMD_RS13985	COG0268	Binds directly to 16S ribosomal RNA
BLMD_RS13995	COG1733	regulation of RNA biosynthetic process
BLMD_RS14000	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS14005	COG1466	dna polymerase III delta subunit
BLMD_RS14015	COG2333	competence protein COMEC
BLMD_RS14015	COG0658	competence protein
BLMD_RS14020	COG2131	deaminase
BLMD_RS14025	COG1596	polysaccharide export
BLMD_RS14025	COG1555	photosystem II stabilization
BLMD_RS14030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLMD_RS14035	COG2226	methyltransferase
BLMD_RS14040	COG0799	negative regulation of ribosome biogenesis
BLMD_RS14045	COG1713	HD superfamily hydrolase involved in NAD metabolism
BLMD_RS14050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLMD_RS14055	COG1534	Rna-binding protein
BLMD_RS14060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLMD_RS14065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BLMD_RS14070	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BLMD_RS14080	COG2755	lipolytic protein G-D-S-L family
BLMD_RS14090	COG5609	conserved protein (DUF2294)
BLMD_RS14095	COG3383	formate dehydrogenase (NAD+) activity
BLMD_RS14100	COG2427	Protein of unknown function (DUF1641)
BLMD_RS14140	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS14145	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_RS14150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS14170	COG1486	melibiose metabolic process
BLMD_RS14185	COG0789	Transcriptional regulator
BLMD_RS14185	COG4978	Transcriptional regulator
BLMD_RS14200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BLMD_RS14205	COG2828	Protein conserved in bacteria
BLMD_RS14215	COG2181	nitrate reductase activity
BLMD_RS14220	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BLMD_RS14225	COG1140	nitrate reductase beta subunit
BLMD_RS14230	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BLMD_RS14235	COG2223	nitrite transmembrane transporter activity
BLMD_RS14245	COG3226	Transcriptional regulator
BLMD_RS14280	COG2197	response regulator
BLMD_RS14285	COG4585	Histidine kinase
BLMD_RS14290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS14295	COG0730	response to heat
BLMD_RS14300	COG0425	Belongs to the sulfur carrier protein TusA family
BLMD_RS14305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS14305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_RS14310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_RS14310	COG0425	Belongs to the sulfur carrier protein TusA family
BLMD_RS14315	COG2210	Belongs to the sulfur carrier protein TusA family
BLMD_RS14320	COG1937	Protein conserved in bacteria
BLMD_RS14345	COG1942	4-Oxalocrotonate Tautomerase
BLMD_RS14350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BLMD_RS14355	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BLMD_RS14360	COG1733	regulation of RNA biosynthetic process
BLMD_RS14365	COG3239	Fatty acid desaturase
BLMD_RS14370	COG4585	Histidine kinase
BLMD_RS14375	COG2197	response regulator
BLMD_RS14380	COG0492	ferredoxin-NADP+ reductase activity
BLMD_RS14385	COG0747	negative chemotaxis
BLMD_RS14395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLMD_RS14400	COG0444	Belongs to the ABC transporter superfamily
BLMD_RS14405	COG4608	Belongs to the ABC transporter superfamily
BLMD_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS14435	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
BLMD_RS14450	COG2124	cytochrome p450
BLMD_RS14455	COG0730	response to heat
BLMD_RS14465	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS14470	COG2211	Major facilitator Superfamily
BLMD_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS14485	COG1621	beta-fructofuranosidase activity
BLMD_RS14490	COG3716	PTS system mannose fructose sorbose family IID component
BLMD_RS14495	COG3715	PTS system
BLMD_RS14500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS14505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS14510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BLMD_RS14510	COG3933	PFAM sigma-54 factor interaction domain-containing protein
BLMD_RS14530	COG2169	Transcriptional regulator
BLMD_RS14535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLMD_RS14540	COG2205	protein histidine kinase activity
BLMD_RS14550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BLMD_RS14555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BLMD_RS14565	COG0656	L-ascorbic acid biosynthetic process
BLMD_RS14570	COG2814	Major facilitator Superfamily
BLMD_RS14575	COG1733	regulation of RNA biosynthetic process
BLMD_RS14580	COG3340	Belongs to the peptidase S51 family
BLMD_RS14585	COG1587	Uroporphyrinogen-III synthase
BLMD_RS14595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS14600	COG0583	DNA-binding transcription factor activity
BLMD_RS14605	COG2814	Major facilitator Superfamily
BLMD_RS14615	COG2124	cytochrome p450
BLMD_RS14615	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLMD_RS14620	COG1309	transcriptional regulator
BLMD_RS14625	COG1404	Belongs to the peptidase S8 family
BLMD_RS14630	COG2226	methyltransferase
BLMD_RS14650	COG0626	cystathionine gamma-synthase activity
BLMD_RS14655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_RS14660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLMD_RS14665	COG2226	methyltransferase
BLMD_RS14680	COG0768	penicillin binding
BLMD_RS14685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLMD_RS14690	COG0572	uridine kinase
BLMD_RS14695	COG0826	peptidase U32
BLMD_RS14700	COG0826	peptidase U32
BLMD_RS14705	COG4122	O-methyltransferase activity
BLMD_RS14710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLMD_RS14715	COG3906	Belongs to the UPF0473 family
BLMD_RS14720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLMD_RS14725	COG4472	Bacterial protein of unknown function (DUF965)
BLMD_RS14730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLMD_RS14735	COG0628	permease
BLMD_RS14750	COG3881	PFAM PRC-barrel domain
BLMD_RS14755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLMD_RS14760	COG0457	Tetratricopeptide repeat
BLMD_RS14765	COG0482	sulfurtransferase activity
BLMD_RS14770	COG1104	cysteine desulfurase activity
BLMD_RS14775	COG1959	2 iron, 2 sulfur cluster binding
BLMD_RS14780	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BLMD_RS14785	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BLMD_RS14795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLMD_RS14800	COG0124	histidyl-tRNA synthetase
BLMD_RS14805	COG4991	sh3 domain protein
BLMD_RS14805	COG3103	Sh3 type 3 domain protein
BLMD_RS14805	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_RS14810	COG1490	D-aminoacyl-tRNA deacylase activity
BLMD_RS14815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLMD_RS14820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLMD_RS14825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BLMD_RS14825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BLMD_RS14830	COG5416	Lipopolysaccharide assembly protein A domain
BLMD_RS14835	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLMD_RS14835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLMD_RS14845	COG2244	polysaccharide biosynthetic process
BLMD_RS14850	COG2323	membrane
BLMD_RS14860	COG1862	Preprotein translocase
BLMD_RS14865	COG0343	queuine tRNA-ribosyltransferase activity
BLMD_RS14870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLMD_RS14880	COG2255	four-way junction helicase activity
BLMD_RS14885	COG0632	four-way junction helicase activity
BLMD_RS14895	COG2112	serine threonine protein kinase
BLMD_RS14905	COG2318	DinB family
BLMD_RS14910	COG4195	phage-related replication protein
BLMD_RS14925	COG0217	transcriptional regulatory protein
BLMD_RS14935	COG1388	LysM domain
BLMD_RS14940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLMD_RS14945	COG0157	Belongs to the NadC ModD family
BLMD_RS14950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLMD_RS14955	COG1104	cysteine desulfurase activity
BLMD_RS14960	COG1827	regulation of RNA biosynthetic process
BLMD_RS14965	COG0077	Prephenate dehydratase
BLMD_RS14970	COG4492	Belongs to the UPF0735 family
BLMD_RS14975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLMD_RS14980	COG3290	protein histidine kinase activity
BLMD_RS14985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BLMD_RS14990	COG2868	ribosomal protein
BLMD_RS14995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLMD_RS15000	COG1994	Peptidase M50
BLMD_RS15005	COG0739	heme binding
BLMD_RS15010	COG3832	glyoxalase III activity
BLMD_RS15015	COG0640	Transcriptional regulator
BLMD_RS15020	COG2894	cell division
BLMD_RS15025	COG0850	regulation of cytokinetic process
BLMD_RS15030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BLMD_RS15040	COG1077	Cell shape determining protein MreB Mrl
BLMD_RS15045	COG2003	Belongs to the UPF0758 family
BLMD_RS15050	COG0424	maF-like protein
BLMD_RS15060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BLMD_RS15065	COG0285	dihydrofolate synthase activity
BLMD_RS15070	COG0525	valine-tRNA ligase activity
BLMD_RS15080	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLMD_RS15085	COG1388	LysM domain
BLMD_RS15090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BLMD_RS15095	COG0113	porphobilinogen synthase activity
BLMD_RS15100	COG1587	Uroporphyrinogen-III synthase
BLMD_RS15105	COG0181	hydroxymethylbilane synthase activity
BLMD_RS15110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLMD_RS15115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BLMD_RS15125	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BLMD_RS15130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BLMD_RS15135	COG0470	DNA polymerase III
BLMD_RS15135	COG1067	ATP-dependent peptidase activity
BLMD_RS15140	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLMD_RS15145	COG0544	peptidyl-prolyl cis-trans isomerase activity
BLMD_RS15150	COG0457	Tetratricopeptide repeat
BLMD_RS15150	COG1477	protein flavinylation
BLMD_RS15155	COG0066	3-isopropylmalate dehydratase activity
BLMD_RS15160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLMD_RS15165	COG0473	3-isopropylmalate dehydrogenase activity
BLMD_RS15170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLMD_RS15175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLMD_RS15180	COG0440	acetolactate synthase activity
BLMD_RS15185	COG0028	Belongs to the TPP enzyme family
BLMD_RS15190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_RS15200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLMD_RS15220	COG0622	Phosphoesterase
BLMD_RS15225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLMD_RS15230	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BLMD_RS15235	COG5401	PFAM Sporulation and spore germination
BLMD_RS15240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLMD_RS15245	COG1846	Transcriptional regulator
BLMD_RS15250	COG2197	response regulator
BLMD_RS15255	COG4221	oxidoreductase activity
BLMD_RS15260	COG0824	Thioesterase
BLMD_RS15265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLMD_RS15270	COG1053	succinate dehydrogenase
BLMD_RS15275	COG2009	succinate dehydrogenase
BLMD_RS15280	COG1719	4-vinyl reductase, 4VR
BLMD_RS15285	COG0527	aspartate kinase activity
BLMD_RS15290	COG0322	excinuclease ABC activity
BLMD_RS15295	COG3118	belongs to the thioredoxin family
BLMD_RS15300	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLMD_RS15305	COG2086	electron transfer activity
BLMD_RS15310	COG1024	Enoyl-CoA hydratase
BLMD_RS15315	COG1309	transcriptional regulator
BLMD_RS15320	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS15325	COG3766	membrane
BLMD_RS15330	COG1193	negative regulation of DNA recombination
BLMD_RS15335	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLMD_RS15335	COG1796	DNA polymerase
BLMD_RS15340	COG1286	toxin biosynthetic process
BLMD_RS15345	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BLMD_RS15350	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLMD_RS15370	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_RS15370	COG0072	phenylalanine-tRNA ligase activity
BLMD_RS15375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLMD_RS15380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLMD_RS15390	COG1966	Carbon starvation protein
BLMD_RS15395	COG1309	transcriptional regulator
BLMD_RS15400	COG3402	PFAM membrane-flanked domain
BLMD_RS15420	COG0395	ABC-type sugar transport system, permease component
BLMD_RS15425	COG1175	transmembrane transport
BLMD_RS15430	COG1653	transport
BLMD_RS15435	COG0371	Dehydrogenase
BLMD_RS15440	COG0235	Class ii aldolase
BLMD_RS15445	COG1069	ribulokinase activity
BLMD_RS15450	COG2160	L-arabinose isomerase activity
BLMD_RS15455	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS15460	COG1363	Peptidase, m42
BLMD_RS15470	COG3326	Membrane
BLMD_RS15475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLMD_RS15480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLMD_RS15485	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLMD_RS15490	COG1346	cytolysis
BLMD_RS15500	COG3540	Alkaline phosphatase
BLMD_RS15505	COG3279	Response regulator of the LytR AlgR family
BLMD_RS15510	COG3275	phosphorelay sensor kinase activity
BLMD_RS15520	COG1011	Hydrolase
BLMD_RS15525	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLMD_RS15535	COG0398	Pfam SNARE associated Golgi protein
BLMD_RS15540	COG1484	DNA-dependent DNA replication
BLMD_RS15545	COG3611	Membrane attachment protein
BLMD_RS15550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLMD_RS15565	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BLMD_RS15570	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLMD_RS15575	COG3866	Pectate lyase
BLMD_RS15580	COG0237	dephospho-CoA kinase activity
BLMD_RS15585	COG1971	Probably functions as a manganese efflux pump
BLMD_RS15590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BLMD_RS15595	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_RS15595	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLMD_RS15600	COG5002	protein histidine kinase activity
BLMD_RS15605	COG0745	RESPONSE REGULATOR receiver
BLMD_RS15610	COG0039	L-malate dehydrogenase activity
BLMD_RS15615	COG0538	isocitrate dehydrogenase activity
BLMD_RS15620	COG0372	Belongs to the citrate synthase family
BLMD_RS15630	COG2273	Hydrolase Family 16
BLMD_RS15635	COG2707	UPF0756 membrane protein
BLMD_RS15640	COG0628	permease
BLMD_RS15645	COG3030	protein affecting phage T7 exclusion by the F plasmid
BLMD_RS15655	COG0205	6-phosphofructokinase activity
BLMD_RS15660	COG0825	malonyl-CoA metabolic process
BLMD_RS15665	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLMD_RS15670	COG0281	malic enzyme
BLMD_RS15675	COG0587	DNA-directed DNA polymerase activity
BLMD_RS15695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLMD_RS15705	COG4109	DRTGG domain
BLMD_RS15710	COG1695	Transcriptional regulator
BLMD_RS15715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLMD_RS15720	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS15725	COG0165	Argininosuccinate lyase
BLMD_RS15730	COG0137	argininosuccinate synthase activity
BLMD_RS15735	COG0521	Mo-molybdopterin cofactor biosynthetic process
BLMD_RS15740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLMD_RS15745	COG0827	DNA restriction-modification system
BLMD_RS15750	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BLMD_RS15755	COG3874	Sporulation protein YtfJ
BLMD_RS15765	COG1714	RDD family
BLMD_RS15770	COG0616	signal peptide processing
BLMD_RS15775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLMD_RS15780	COG1846	Transcriptional regulator
BLMD_RS15785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_RS15795	COG0301	tRNA thio-modification
BLMD_RS15800	COG1104	cysteine desulfurase activity
BLMD_RS15805	COG1114	Component of the transport system for branched-chain amino acids
BLMD_RS15810	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BLMD_RS15815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BLMD_RS15820	COG1309	transcriptional regulator
BLMD_RS15825	COG1956	GAF domain-containing protein
BLMD_RS15830	COG2199	diguanylate cyclase activity
BLMD_RS15830	COG2203	Gaf domain
BLMD_RS15835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLMD_RS15850	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLMD_RS15855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLMD_RS15860	COG0454	-acetyltransferase
BLMD_RS15865	COG0517	IMP dehydrogenase activity
BLMD_RS15870	COG0123	including yeast histone deacetylase and acetoin utilization protein
BLMD_RS15875	COG1360	Flagellar Motor Protein
BLMD_RS15880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLMD_RS15885	COG1609	Transcriptional regulator
BLMD_RS15890	COG1605	Chorismate mutase
BLMD_RS15890	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BLMD_RS15900	COG3118	belongs to the thioredoxin family
BLMD_RS15905	COG4980	gas vesicle protein
BLMD_RS15910	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BLMD_RS15915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLMD_RS15920	COG1674	ftsk spoiiie
BLMD_RS15925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLMD_RS15930	COG4848	Belongs to the UPF0354 family
BLMD_RS15935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS15945	COG1363	Peptidase, m42
BLMD_RS15950	COG5584	Small secreted protein
BLMD_RS15955	COG0281	malic enzyme
BLMD_RS15960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLMD_RS15965	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BLMD_RS15975	COG0510	thiamine kinase activity
BLMD_RS15980	COG1523	belongs to the glycosyl hydrolase 13 family
BLMD_RS15985	COG1597	lipid kinase activity
BLMD_RS15995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLMD_RS16000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLMD_RS16015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLMD_RS16020	COG2252	PERMEase
BLMD_RS16025	COG4473	ABC transporter
BLMD_RS16030	COG1131	(ABC) transporter
BLMD_RS16035	COG1349	DNA-binding transcription factor activity
BLMD_RS16040	COG1187	pseudouridine synthase activity
BLMD_RS16045	COG2244	polysaccharide biosynthetic process
BLMD_RS16050	COG2081	HI0933 family
BLMD_RS16055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BLMD_RS16065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_RS16080	COG5578	integral membrane protein
BLMD_RS16085	COG0673	inositol 2-dehydrogenase activity
BLMD_RS16090	COG1653	transport
BLMD_RS16095	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BLMD_RS16100	COG4209	transmembrane transport
BLMD_RS16105	COG2207	Transcriptional regulator
BLMD_RS16110	COG1653	transport
BLMD_RS16115	COG0395	ABC-type sugar transport system, permease component
BLMD_RS16120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_RS16125	COG1073	alpha beta
BLMD_RS16135	COG0583	DNA-binding transcription factor activity
BLMD_RS16140	COG0346	lactoylglutathione lyase activity
BLMD_RS16145	COG0495	leucyl-tRNA aminoacylation
BLMD_RS16155	COG2814	Major facilitator Superfamily
BLMD_RS16160	COG1464	Belongs to the NlpA lipoprotein family
BLMD_RS16165	COG2433	Pfam Transposase IS66
BLMD_RS16170	COG0577	efflux transmembrane transporter activity
BLMD_RS16175	COG1136	(ABC) transporter
BLMD_RS16185	COG1131	(ABC) transporter
BLMD_RS16190	COG1725	Transcriptional regulator
BLMD_RS16200	COG1242	4 iron, 4 sulfur cluster binding
BLMD_RS16205	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BLMD_RS16215	COG2267	carboxylic ester hydrolase activity
BLMD_RS16220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BLMD_RS16225	COG0671	phosphoesterase, PA-phosphatase related
BLMD_RS16230	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS16230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_RS16235	COG0367	asparagine synthase
BLMD_RS16240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLMD_RS16245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BLMD_RS16260	COG1506	peptidase
BLMD_RS16265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLMD_RS16270	COG1116	anion transmembrane transporter activity
BLMD_RS16275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLMD_RS16280	COG0494	nUDIX hydrolase
BLMD_RS16290	COG4824	toxin secretion phage lysis holin
BLMD_RS16295	COG0783	Belongs to the Dps family
BLMD_RS16310	COG1854	S-ribosylhomocysteine lyase activity
BLMD_RS16315	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLMD_RS16320	COG0288	reversible hydration of carbon dioxide
BLMD_RS16325	COG0523	cobalamin synthesis protein
BLMD_RS16330	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLMD_RS16335	COG0254	rRNA binding
BLMD_RS16340	COG1271	oxidase subunit
BLMD_RS16345	COG1294	oxidase, subunit
BLMD_RS16360	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_RS16365	COG0318	PFAM AMP-dependent synthetase and ligase
BLMD_RS16370	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BLMD_RS16375	COG0596	Alpha beta hydrolase
BLMD_RS16380	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BLMD_RS16385	COG1169	isochorismate synthase
BLMD_RS16390	COG1575	Belongs to the MenA family. Type 1 subfamily
BLMD_RS16395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BLMD_RS16400	COG0058	SHG alpha-glucan phosphorylase activity
BLMD_RS16405	COG0297	glycogen (starch) synthase activity
BLMD_RS16410	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLMD_RS16415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLMD_RS16420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BLMD_RS16545	COG1609	Transcriptional regulator
BLMD_RS16550	COG3859	Proton-coupled thiamine transporter YuaJ
BLMD_RS16555	COG3764	Sortase (surface protein transpeptidase)
BLMD_RS16570	COG0457	Tetratricopeptide repeat
BLMD_RS16575	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLMD_RS16580	COG0569	domain protein
BLMD_RS16585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_RS16595	COG2318	DinB family
BLMD_RS16605	COG1454	alcohol dehydrogenase
BLMD_RS16610	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS16615	COG1510	regulation of RNA biosynthetic process
BLMD_RS16625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BLMD_RS16630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLMD_RS16645	COG1397	ADP-ribosylglycohydrolase
BLMD_RS16740	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BLMD_RS16750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLMD_RS16755	COG0726	polysaccharide deacetylase
BLMD_RS16760	COG1408	metallophosphoesterase
BLMD_RS16765	COG1968	undecaprenyl-diphosphatase activity
BLMD_RS16770	COG0628	permease
BLMD_RS16775	COG0673	inositol 2-dehydrogenase activity
BLMD_RS16780	COG0693	protein deglycase activity
BLMD_RS16785	COG0840	transmembrane signaling receptor activity
BLMD_RS16790	COG0840	transmembrane signaling receptor activity
BLMD_RS16795	COG0840	transmembrane signaling receptor activity
BLMD_RS16805	COG2070	2-Nitropropane dioxygenase
BLMD_RS16810	COG0432	Pfam Uncharacterised protein family UPF0047
BLMD_RS16815	COG0366	Alpha amylase catalytic
BLMD_RS16830	COG5297	Belongs to the glycosyl hydrolase family 6
BLMD_RS16835	COG1253	flavin adenine dinucleotide binding
BLMD_RS16840	COG2738	Putative neutral zinc metallopeptidase
BLMD_RS16855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLMD_RS16865	COG2323	membrane
BLMD_RS16870	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BLMD_RS16880	COG0166	Belongs to the GPI family
BLMD_RS16885	COG1979	alcohol dehydrogenase
BLMD_RS16890	COG2155	Conserved Protein
BLMD_RS16895	COG1098	S1 RNA binding domain
BLMD_RS16900	COG0436	Aminotransferase
BLMD_RS16905	COG1522	sequence-specific DNA binding
BLMD_RS16910	COG2267	carboxylic ester hydrolase activity
BLMD_RS16925	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLMD_RS16940	COG5018	Exonuclease
BLMD_RS16945	COG2814	Major facilitator Superfamily
BLMD_RS16950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_RS16955	COG3011	Protein conserved in bacteria
BLMD_RS16965	COG3290	protein histidine kinase activity
BLMD_RS16970	COG4565	transcriptional regulatory protein
BLMD_RS16975	COG1079	Belongs to the binding-protein-dependent transport system permease family
BLMD_RS16980	COG1183	phosphatidylcholine synthase activity
BLMD_RS16985	COG0586	Pfam SNARE associated Golgi protein
BLMD_RS16990	COG0688	phosphatidylethanolamine metabolic process
BLMD_RS16995	COG3493	citrate carrier protein
BLMD_RS17005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLMD_RS17005	COG2111	Na H antiporter
BLMD_RS17010	COG2111	Na H antiporter
BLMD_RS17015	COG1006	Multisubunit Na H antiporter MnhC subunit
BLMD_RS17020	COG0651	ATP synthesis coupled electron transport
BLMD_RS17025	COG1863	multisubunit Na H antiporter MnhE subunit
BLMD_RS17030	COG2212	antiporter activity
BLMD_RS17035	COG1320	monovalent cation:proton antiporter activity
BLMD_RS17040	COG2050	protein possibly involved in aromatic compounds catabolism
BLMD_RS17045	COG2197	response regulator
BLMD_RS17060	COG0142	geranyltranstransferase activity
BLMD_RS17080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BLMD_RS17085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLMD_RS17090	COG1335	isochorismatase
BLMD_RS17095	COG5506	Protein of unknown function (DUF1694)
BLMD_RS17110	COG0628	permease
BLMD_RS17115	COG1959	2 iron, 2 sulfur cluster binding
BLMD_RS17120	COG0657	acetylesterase activity
BLMD_RS17130	COG1418	mRNA catabolic process
BLMD_RS17135	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS17150	COG1511	domain protein
BLMD_RS17155	COG1674	ftsk spoiiie
BLMD_RS17155	COG0433	COG0433 Predicted ATPase
BLMD_RS17160	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLMD_RS17165	COG5417	Belongs to the EsaB family
BLMD_RS17170	COG4842	Belongs to the WXG100 family
BLMD_RS17175	COG1115	amino acid carrier protein
BLMD_RS17180	COG2508	Transcriptional regulator
BLMD_RS17180	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BLMD_RS17185	COG0686	Belongs to the AlaDH PNT family
BLMD_RS17195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLMD_RS17200	COG1268	BioY protein
BLMD_RS17205	COG2056	Na+-H+ antiporter family
BLMD_RS17210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLMD_RS17215	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BLMD_RS17220	COG3584	3D domain protein
BLMD_RS17230	COG1252	NADH dehydrogenase
BLMD_RS17235	COG0492	ferredoxin-NADP+ reductase activity
BLMD_RS17250	COG0456	acetyltransferase
BLMD_RS17255	COG0316	Belongs to the HesB IscA family
BLMD_RS17260	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLMD_RS17265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_RS17270	COG4844	belongs to the
BLMD_RS17275	COG1252	NADH dehydrogenase
BLMD_RS17280	COG5646	InterPro IPR014922
BLMD_RS17295	COG0457	Tetratricopeptide repeat
BLMD_RS17300	COG3479	Phenolic acid decarboxylase
BLMD_RS17310	COG4837	Protein of unknown function (DUF1462)
BLMD_RS17315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BLMD_RS17320	COG0823	Involved in the tonB-independent uptake of proteins
BLMD_RS17320	COG4946	Tricorn protease homolog
BLMD_RS17320	COG1506	peptidase
BLMD_RS17325	COG0083	homoserine kinase activity
BLMD_RS17330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BLMD_RS17335	COG0460	homoserine dehydrogenase
BLMD_RS17340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_RS17345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLMD_RS17350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BLMD_RS17355	COG0647	UMP catabolic process
BLMD_RS17360	COG2445	Protein of unknown function DUF86
BLMD_RS17365	COG4470	Protein conserved in bacteria
BLMD_RS17380	COG0739	heme binding
BLMD_RS17390	COG0733	neurotransmitter:sodium symporter activity
BLMD_RS17400	COG3377	Domain of unknown function (DUF1805)
BLMD_RS17405	COG0737	Belongs to the 5'-nucleotidase family
BLMD_RS17410	COG0730	response to heat
BLMD_RS17415	COG1801	Protein of unknown function DUF72
BLMD_RS17425	COG3226	Transcriptional regulator
BLMD_RS17430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BLMD_RS17435	COG2508	Transcriptional regulator
BLMD_RS17440	COG2814	Major facilitator Superfamily
BLMD_RS17445	COG1288	antiporter activity
BLMD_RS17450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLMD_RS17460	COG2356	endonuclease I
BLMD_RS17470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLMD_RS17485	COG0457	Tetratricopeptide repeat
BLMD_RS17495	COG0719	Fe-S assembly protein
BLMD_RS17500	COG0822	iron-sulfur transferase activity
BLMD_RS17505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLMD_RS17510	COG0719	Fe-S assembly protein
BLMD_RS17515	COG0396	ATPase activity
BLMD_RS17525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLMD_RS17530	COG1464	Belongs to the NlpA lipoprotein family
BLMD_RS17535	COG2011	ABC-type metal ion transport system permease component
BLMD_RS17540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLMD_RS17550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLMD_RS17555	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BLMD_RS17565	COG0509	glycine decarboxylation via glycine cleavage system
BLMD_RS17570	COG1393	Belongs to the ArsC family
BLMD_RS17575	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS17580	COG0183	Belongs to the thiolase family
BLMD_RS17585	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLMD_RS17585	COG1024	Enoyl-CoA hydratase
BLMD_RS17600	COG5577	PFAM Coat F domain
BLMD_RS17615	COG1120	ATPase activity
BLMD_RS17620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS17625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS17630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS17645	COG1686	Belongs to the peptidase S11 family
BLMD_RS17650	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS17655	COG0783	Belongs to the Dps family
BLMD_RS17660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_RS17665	COG0745	RESPONSE REGULATOR receiver
BLMD_RS17670	COG2205	protein histidine kinase activity
BLMD_RS17670	COG2770	Histidine kinase
BLMD_RS17675	COG1309	transcriptional regulator
BLMD_RS17680	COG0114	fumarate hydratase activity
BLMD_RS17690	COG0697	spore germination
BLMD_RS17695	COG0814	amino acid
BLMD_RS17710	COG2197	response regulator
BLMD_RS17715	COG4585	Histidine kinase
BLMD_RS17720	COG4758	membrane
BLMD_RS17730	COG1842	Phage shock protein A
BLMD_RS17735	COG4758	membrane
BLMD_RS17740	COG4677	pectinesterase activity
BLMD_RS17745	COG2096	Adenosyltransferase
BLMD_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS17755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_RS17760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_RS17775	COG1454	alcohol dehydrogenase
BLMD_RS17780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_RS17785	COG1120	ATPase activity
BLMD_RS17790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS17795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS17800	COG1802	Transcriptional regulator
BLMD_RS17805	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS17810	COG2258	MOSC domain
BLMD_RS17815	COG0583	DNA-binding transcription factor activity
BLMD_RS17825	COG2721	sulfolactate sulfo-lyase activity
BLMD_RS17830	COG0246	Mannitol dehydrogenase
BLMD_RS17835	COG1609	Transcriptional regulator
BLMD_RS17840	COG2211	Major facilitator Superfamily
BLMD_RS17845	COG1904	glucuronate isomerase
BLMD_RS17850	COG2205	protein histidine kinase activity
BLMD_RS17855	COG0745	RESPONSE REGULATOR receiver
BLMD_RS17860	COG1120	ATPase activity
BLMD_RS17865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS17870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS17875	COG0531	amino acid
BLMD_RS17885	COG1988	membrane-bound metal-dependent
BLMD_RS17890	COG1368	sulfuric ester hydrolase activity
BLMD_RS17895	COG2814	Major facilitator Superfamily
BLMD_RS17900	COG0656	L-ascorbic acid biosynthetic process
BLMD_RS17905	COG1940	carbohydrate kinase activity
BLMD_RS17910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLMD_RS17920	COG0596	Alpha beta hydrolase
BLMD_RS17925	COG3973	AAA domain
BLMD_RS17930	COG2860	membrane
BLMD_RS17935	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BLMD_RS17935	COG0456	acetyltransferase
BLMD_RS17940	COG0456	acetyltransferase
BLMD_RS17945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BLMD_RS17950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BLMD_RS17955	COG2217	Heavy metal translocating P-type atpase
BLMD_RS17960	COG1653	transport
BLMD_RS17965	COG1175	transmembrane transport
BLMD_RS17970	COG0395	ABC-type sugar transport system, permease component
BLMD_RS17975	COG1501	Belongs to the glycosyl hydrolase 31 family
BLMD_RS17980	COG1472	Belongs to the glycosyl hydrolase 3 family
BLMD_RS17985	COG1121	(ABC) transporter
BLMD_RS17990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLMD_RS17995	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLMD_RS18015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS18015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS18015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLMD_RS18020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS18030	COG2217	Heavy metal translocating P-type atpase
BLMD_RS18035	COG2608	mercury ion transmembrane transporter activity
BLMD_RS18040	COG1937	Protein conserved in bacteria
BLMD_RS18045	COG0693	protein deglycase activity
BLMD_RS18050	COG1349	DNA-binding transcription factor activity
BLMD_RS18055	COG1070	Carbohydrate kinase
BLMD_RS18060	COG4952	isomerase
BLMD_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS18070	COG3347	Dehydrogenase
BLMD_RS18075	COG2814	Major facilitator Superfamily
BLMD_RS18080	COG2814	Major facilitator Superfamily
BLMD_RS18090	COG2124	cytochrome p450
BLMD_RS18100	COG1846	Transcriptional regulator
BLMD_RS18110	COG0673	inositol 2-dehydrogenase activity
BLMD_RS18115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BLMD_RS18120	COG1054	Belongs to the UPF0176 family
BLMD_RS18130	COG1191	sigma factor activity
BLMD_RS18140	COG2140	Oxalate decarboxylase
BLMD_RS18160	COG5520	Belongs to the glycosyl hydrolase 30 family
BLMD_RS18165	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS18180	COG5444	nuclease activity
BLMD_RS18200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLMD_RS18205	COG0557	exoribonuclease II activity
BLMD_RS18210	COG1647	Serine aminopeptidase, S33
BLMD_RS18215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLMD_RS18220	COG2002	toxin-antitoxin pair type II binding
BLMD_RS18225	COG1476	TRANSCRIPTIONal
BLMD_RS18230	COG1396	sequence-specific DNA binding
BLMD_RS18235	COG1396	sequence-specific DNA binding
BLMD_RS18240	COG1174	glycine betaine transport
BLMD_RS18245	COG1732	Glycine betaine
BLMD_RS18250	COG1174	glycine betaine transport
BLMD_RS18255	COG1125	glycine betaine transport
BLMD_RS18255	COG0517	IMP dehydrogenase activity
BLMD_RS18260	COG1510	regulation of RNA biosynthetic process
BLMD_RS18265	COG2095	MarC family integral membrane protein
BLMD_RS18270	COG3064	Membrane
BLMD_RS18275	COG4640	response to antibiotic
BLMD_RS18280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS18295	COG0693	protein deglycase activity
BLMD_RS18300	COG0148	phosphopyruvate hydratase activity
BLMD_RS18305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLMD_RS18310	COG0149	triose-phosphate isomerase activity
BLMD_RS18315	COG0126	phosphoglycerate kinase activity
BLMD_RS18320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLMD_RS18325	COG2390	Transcriptional regulator
BLMD_RS18330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_RS18335	COG1113	amino acid transport
BLMD_RS18360	COG1556	Lactate utilization protein
BLMD_RS18365	COG1139	Iron-sulfur cluster binding protein
BLMD_RS18370	COG0247	lactate metabolic process
BLMD_RS18375	COG2186	Transcriptional regulator
BLMD_RS18380	COG1620	l-lactate permease
BLMD_RS18385	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLMD_RS18395	COG5039	Polysaccharide pyruvyl transferase
BLMD_RS18400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_RS18405	COG0110	maltose O-acetyltransferase activity
BLMD_RS18410	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLMD_RS18415	COG2244	polysaccharide biosynthetic process
BLMD_RS18420	COG1216	Glycosyl transferase, family 2
BLMD_RS18425	COG5039	Polysaccharide pyruvyl transferase
BLMD_RS18430	COG1216	Glycosyl transferase, family 2
BLMD_RS18440	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS18445	COG1215	transferase activity, transferring glycosyl groups
BLMD_RS18450	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS18455	COG1086	Polysaccharide biosynthesis protein
BLMD_RS18460	COG0489	protein tyrosine kinase activity
BLMD_RS18465	COG3944	biosynthesis protein
BLMD_RS18470	COG1396	sequence-specific DNA binding
BLMD_RS18475	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS18480	COG2271	Major facilitator Superfamily
BLMD_RS18490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLMD_RS18500	COG1454	alcohol dehydrogenase
BLMD_RS18505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLMD_RS18515	COG1733	regulation of RNA biosynthetic process
BLMD_RS18520	COG1902	pentaerythritol trinitrate reductase activity
BLMD_RS18525	COG1621	beta-fructofuranosidase activity
BLMD_RS18530	COG1621	beta-fructofuranosidase activity
BLMD_RS18545	COG0740	serine-type endopeptidase activity
BLMD_RS18550	COG1611	Belongs to the LOG family
BLMD_RS18555	COG1694	Mazg nucleotide pyrophosphohydrolase
BLMD_RS18560	COG1078	dGTPase activity
BLMD_RS18565	COG0659	secondary active sulfate transmembrane transporter activity
BLMD_RS18570	COG0288	reversible hydration of carbon dioxide
BLMD_RS18575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_RS18580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLMD_RS18585	COG0640	Transcriptional regulator
BLMD_RS18595	COG2732	(Barnase) inhibitor
BLMD_RS18600	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BLMD_RS18605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS18610	COG1481	regulation of sporulation
BLMD_RS18615	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BLMD_RS18620	COG1660	Displays ATPase and GTPase activities
BLMD_RS18625	COG1051	belongs to the nudix hydrolase family
BLMD_RS18635	COG0492	ferredoxin-NADP+ reductase activity
BLMD_RS18640	COG0457	Tetratricopeptide repeat
BLMD_RS18645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLMD_RS18650	COG0140	phosphoribosyl-ATP diphosphatase activity
BLMD_RS18650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLMD_RS18655	COG0107	imidazoleglycerol-phosphate synthase activity
BLMD_RS18660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLMD_RS18665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLMD_RS18670	COG0131	Imidazoleglycerol-phosphate dehydratase
BLMD_RS18675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BLMD_RS18680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLMD_RS18685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLMD_RS18690	COG4990	cell redox homeostasis
BLMD_RS18695	COG5297	Belongs to the glycosyl hydrolase family 6
BLMD_RS18700	COG0110	maltose O-acetyltransferase activity
BLMD_RS18705	COG0546	phosphoglycolate phosphatase activity
BLMD_RS18710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLMD_RS18715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLMD_RS18720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BLMD_RS18725	COG1846	Transcriptional regulator
BLMD_RS18730	COG2814	Major facilitator Superfamily
BLMD_RS18735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BLMD_RS18740	COG1950	PFAM Membrane protein of
BLMD_RS18745	COG1983	PspC domain protein
BLMD_RS18750	COG3595	metallopeptidase activity
BLMD_RS18770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLMD_RS18775	COG0556	nucleotide-excision repair
BLMD_RS18780	COG4897	Protein conserved in bacteria
BLMD_RS18790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_RS18800	COG0793	Belongs to the peptidase S41A family
BLMD_RS18800	COG3409	Peptidoglycan-binding domain 1 protein
BLMD_RS18805	COG0473	3-isopropylmalate dehydrogenase activity
BLMD_RS18810	COG3883	PFAM NLP P60 protein
BLMD_RS18810	COG0791	NLP P60 protein
BLMD_RS18815	COG2177	Part of the ABC transporter FtsEX involved in
BLMD_RS18820	COG2884	Cell division ATP-binding protein ftsE
BLMD_RS18830	COG2010	Cytochrome c
BLMD_RS18835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS18840	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLMD_RS18845	COG0653	protein targeting
BLMD_RS18850	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLMD_RS18865	COG1516	flagellar protein fliS
BLMD_RS18870	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BLMD_RS18875	COG1334	flagellar protein FlaG
BLMD_RS18885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLMD_RS18890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BLMD_RS18895	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BLMD_RS18905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLMD_RS18910	COG4786	Flagellar basal body rod
BLMD_RS18910	COG1256	bacterial-type flagellum assembly
BLMD_RS18915	COG3418	PFAM FlgN family protein
BLMD_RS18920	COG2747	anti-sigma28 factor FlgM
BLMD_RS18930	COG1040	competence protein
BLMD_RS18940	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BLMD_RS18945	COG1307	EDD domain protein, DegV family
BLMD_RS18950	COG2197	response regulator
BLMD_RS18955	COG4585	Histidine kinase
BLMD_RS18960	COG1739	Uncharacterized protein family UPF0029
BLMD_RS18965	COG1316	TRANSCRIPTIONal
BLMD_RS18975	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLMD_RS18980	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS18985	COG1215	transferase activity, transferring glycosyl groups
BLMD_RS18990	COG3206	protein involved in exopolysaccharide biosynthesis
BLMD_RS18995	COG3307	-O-antigen
BLMD_RS19000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLMD_RS19005	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BLMD_RS19010	COG0438	transferase activity, transferring glycosyl groups
BLMD_RS19010	COG0297	glycogen (starch) synthase activity
BLMD_RS19015	COG2244	polysaccharide biosynthetic process
BLMD_RS19025	COG2247	cell wall binding repeat
BLMD_RS19025	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLMD_RS19030	COG2385	sporulation resulting in formation of a cellular spore
BLMD_RS19030	COG2247	cell wall binding repeat
BLMD_RS19040	COG1316	TRANSCRIPTIONal
BLMD_RS19050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BLMD_RS19055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLMD_RS19075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_RS19095	COG1134	teichoic acid transport
BLMD_RS19100	COG1682	transport, permease protein
BLMD_RS19105	COG0463	Glycosyl transferase, family 2
BLMD_RS19105	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_RS19110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_RS19115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLMD_RS19120	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BLMD_RS19125	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BLMD_RS19130	COG4193	domain, Protein
BLMD_RS19135	COG1482	cell wall glycoprotein biosynthetic process
BLMD_RS19155	COG0800	Aldolase
BLMD_RS19160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_RS19165	COG1609	Transcriptional regulator
BLMD_RS19170	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BLMD_RS19175	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS19180	COG1063	alcohol dehydrogenase
BLMD_RS19185	COG2814	Major facilitator Superfamily
BLMD_RS19190	COG1316	TRANSCRIPTIONal
BLMD_RS19195	COG0561	phosphatase activity
BLMD_RS19200	COG0791	NLP P60 protein
BLMD_RS19205	COG2843	Capsule synthesis protein
BLMD_RS19215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLMD_RS19220	COG1609	Transcriptional regulator
BLMD_RS19225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_RS19230	COG1869	D-ribose catabolic process
BLMD_RS19235	COG1129	ABC transporter
BLMD_RS19240	COG1172	Belongs to the binding-protein-dependent transport system permease family
BLMD_RS19245	COG1879	ABC-type sugar transport system periplasmic component
BLMD_RS19250	COG0583	DNA-binding transcription factor activity
BLMD_RS19255	COG2226	methyltransferase
BLMD_RS19260	COG3527	Alpha-acetolactate decarboxylase
BLMD_RS19265	COG0028	Belongs to the TPP enzyme family
BLMD_RS19270	COG0583	DNA-binding transcription factor activity
BLMD_RS19275	COG0405	Gamma-glutamyltransferase
BLMD_RS19280	COG1522	sequence-specific DNA binding
BLMD_RS19285	COG2059	Chromate
BLMD_RS19290	COG2059	Chromate
BLMD_RS19295	COG4464	protein tyrosine phosphatase activity
BLMD_RS19300	COG3944	biosynthesis protein
BLMD_RS19305	COG4715	Zinc finger, swim domain protein
BLMD_RS19310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLMD_RS19320	COG3878	Protein conserved in bacteria
BLMD_RS19340	COG0561	phosphatase activity
BLMD_RS19345	COG1349	DNA-binding transcription factor activity
BLMD_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS19365	COG3732	PTS system glucitol sorbitol-specific
BLMD_RS19385	COG0629	single-stranded DNA binding
BLMD_RS19400	COG1970	mechanosensitive ion channel activity
BLMD_RS19405	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLMD_RS19410	COG4786	Flagellar basal body rod
BLMD_RS19415	COG4786	Flagellar basal body rod
BLMD_RS19420	COG1077	Cell shape determining protein MreB Mrl
BLMD_RS19425	COG1609	Transcriptional regulator
BLMD_RS19435	COG1846	Transcriptional regulator
BLMD_RS19440	COG2814	Major facilitator Superfamily
BLMD_RS19445	COG0671	phosphoesterase, PA-phosphatase related
BLMD_RS19450	COG1227	inorganic diphosphatase activity
BLMD_RS19455	COG3546	catalase activity
BLMD_RS19460	COG3361	conserved protein (COG2071)
BLMD_RS19475	COG0517	IMP dehydrogenase activity
BLMD_RS19480	COG0598	Magnesium transport protein CorA
BLMD_RS19485	COG1253	flavin adenine dinucleotide binding
BLMD_RS19495	COG0347	Belongs to the P(II) protein family
BLMD_RS19505	COG0740	serine-type endopeptidase activity
BLMD_RS19515	COG0739	heme binding
BLMD_RS19520	COG1247	-acetyltransferase
BLMD_RS19530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_RS19535	COG0477	Major facilitator Superfamily
BLMD_RS19540	COG3251	PFAM MbtH domain protein
BLMD_RS19545	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS19550	COG1535	isochorismatase
BLMD_RS19550	COG3433	isochorismatase activity
BLMD_RS19555	COG1021	2,3-dihydroxybenzoate-AMP ligase
BLMD_RS19560	COG1169	isochorismate synthase
BLMD_RS19565	COG1028	Short-chain dehydrogenase reductase Sdr
BLMD_RS19570	COG2819	hydrolase of the alpha beta superfamily
BLMD_RS19575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS19580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS19585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS19590	COG2207	Transcriptional regulator
BLMD_RS19590	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS19600	COG2910	NAD(P)H-binding
BLMD_RS19605	COG1959	2 iron, 2 sulfur cluster binding
BLMD_RS19615	COG1994	Peptidase M50
BLMD_RS19620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BLMD_RS19625	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BLMD_RS19630	COG2223	nitrite transmembrane transporter activity
BLMD_RS19635	COG3383	formate dehydrogenase (NAD+) activity
BLMD_RS19640	COG2304	oxidoreductase activity
BLMD_RS19645	COG2304	oxidoreductase activity
BLMD_RS19650	COG2385	sporulation resulting in formation of a cellular spore
BLMD_RS19655	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLMD_RS19665	COG4836	Membrane
BLMD_RS19670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLMD_RS19675	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLMD_RS19680	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLMD_RS19685	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLMD_RS19690	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLMD_RS19695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLMD_RS19705	COG0356	it plays a direct role in the translocation of protons across the membrane
BLMD_RS19720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BLMD_RS19725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLMD_RS19730	COG4475	Protein of unknown function (DUF436)
BLMD_RS19735	COG0698	ribose 5-phosphate isomerase
BLMD_RS19740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLMD_RS19745	COG1971	Probably functions as a manganese efflux pump
BLMD_RS19750	COG0009	L-threonylcarbamoyladenylate synthase
BLMD_RS19755	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BLMD_RS19765	COG0738	Major facilitator superfamily
BLMD_RS19770	COG0673	inositol 2-dehydrogenase activity
BLMD_RS19775	COG0561	phosphatase activity
BLMD_RS19780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BLMD_RS19785	COG1609	Transcriptional regulator
BLMD_RS19795	COG2890	protein-(glutamine-N5) methyltransferase activity
BLMD_RS19800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLMD_RS19805	COG0346	lactoylglutathione lyase activity
BLMD_RS19810	COG0789	Transcriptional regulator
BLMD_RS19815	COG0679	Auxin Efflux Carrier
BLMD_RS19820	COG0281	malic enzyme
BLMD_RS19825	COG1435	thymidine kinase activity
BLMD_RS19830	COG0254	rRNA binding
BLMD_RS19835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BLMD_RS19840	COG1494	fructose-1,6-bisphosphatase
BLMD_RS19845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLMD_RS19850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLMD_RS19855	COG0191	fructose-bisphosphate aldolase activity
BLMD_RS19860	COG2204	response regulator
BLMD_RS19865	COG4821	SIS domain
BLMD_RS19870	COG0504	CTP synthase activity
BLMD_RS19875	COG3343	RNA polymerase activity
BLMD_RS19880	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS19885	COG1960	acyl-CoA dehydrogenase activity
BLMD_RS19890	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLMD_RS19895	COG0183	Belongs to the thiolase family
BLMD_RS19900	COG0247	lactate metabolic process
BLMD_RS19900	COG2181	nitrate reductase activity
BLMD_RS19905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BLMD_RS19915	COG0018	arginyl-trna synthetase
BLMD_RS19920	COG4506	Protein conserved in bacteria
BLMD_RS19925	COG0010	Belongs to the arginase family
BLMD_RS19930	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BLMD_RS19935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLMD_RS19945	COG1994	Peptidase M50
BLMD_RS19950	COG1942	4-Oxalocrotonate Tautomerase
BLMD_RS19960	COG3465	dGTPase activity
BLMD_RS19965	COG1078	dGTPase activity
BLMD_RS19970	COG4844	belongs to the
BLMD_RS19995	COG2814	Major facilitator Superfamily
BLMD_RS20020	COG1414	Transcriptional regulator
BLMD_RS20030	COG0280	phosphate acetyltransferase
BLMD_RS20035	COG3253	May function as heme-dependent peroxidase
BLMD_RS20050	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLMD_RS20070	COG1131	(ABC) transporter
BLMD_RS20085	COG2363	Small membrane protein
BLMD_RS20090	COG2233	PERMEase
BLMD_RS20100	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS20105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLMD_RS20110	COG1216	Glycosyl transferase, family 2
BLMD_RS20115	COG0351	phosphomethylpyrimidine kinase
BLMD_RS20125	COG1621	beta-fructofuranosidase activity
BLMD_RS20130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS20130	COG1263	PTS System
BLMD_RS20135	COG3711	transcriptional antiterminator
BLMD_RS20145	COG1404	Belongs to the peptidase S8 family
BLMD_RS20155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BLMD_RS20160	COG0778	Nitroreductase
BLMD_RS20165	COG1473	amidohydrolase
BLMD_RS20170	COG0772	Belongs to the SEDS family
BLMD_RS20175	COG0772	Belongs to the SEDS family
BLMD_RS20180	COG3314	Sporulation integral membrane protein YlbJ
BLMD_RS20195	COG0456	acetyltransferase
BLMD_RS20235	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BLMD_RS20245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BLMD_RS20250	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BLMD_RS20255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_RS20270	COG0655	NAD(P)H dehydrogenase (quinone) activity
BLMD_RS20275	COG3162	membrane
BLMD_RS20280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS20285	COG1070	Carbohydrate kinase
BLMD_RS20290	COG2115	Belongs to the xylose isomerase family
BLMD_RS20295	COG1940	carbohydrate kinase activity
BLMD_RS20300	COG0352	thiamine-phosphate diphosphorylase activity
BLMD_RS20305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BLMD_RS20310	COG0583	DNA-binding transcription factor activity
BLMD_RS20325	COG1380	Effector of murein hydrolase LrgA
BLMD_RS20330	COG1346	cytolysis
BLMD_RS20340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLMD_RS20345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BLMD_RS20350	COG0346	lactoylglutathione lyase activity
BLMD_RS20355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLMD_RS20360	COG1442	glycosyl transferase family 8
BLMD_RS20365	COG4585	Histidine kinase
BLMD_RS20370	COG2197	response regulator
BLMD_RS20375	COG2409	Drug exporters of the RND superfamily
BLMD_RS20380	COG5522	Integral membrane protein (intg_mem_TP0381)
BLMD_RS20385	COG2271	Major facilitator Superfamily
BLMD_RS20390	COG4948	Mandelate Racemase Muconate Lactonizing
BLMD_RS20395	COG0800	Aldolase
BLMD_RS20400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_RS20410	COG2234	aminopeptidase activity
BLMD_RS20415	COG0477	Major facilitator Superfamily
BLMD_RS20430	COG2357	RelA SpoT domain protein
BLMD_RS20445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLMD_RS20450	COG1696	Membrane protein involved in D-alanine export
BLMD_RS20455	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLMD_RS20460	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BLMD_RS20465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLMD_RS20470	COG2814	Major facilitator Superfamily
BLMD_RS20475	COG1486	melibiose metabolic process
BLMD_RS20480	COG1447	Phosphotransferase system cellobiose-specific component IIA
BLMD_RS20485	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS20490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS20495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLMD_RS20495	COG3711	transcriptional antiterminator
BLMD_RS20500	COG2094	Belongs to the DNA glycosylase MPG family
BLMD_RS20510	COG0372	Belongs to the citrate synthase family
BLMD_RS20515	COG2079	MmgE PrpD family protein
BLMD_RS20520	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BLMD_RS20535	COG1132	(ABC) transporter
BLMD_RS20540	COG2755	lipolytic protein G-D-S-L family
BLMD_RS20555	COG2814	Major facilitator Superfamily
BLMD_RS20560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BLMD_RS20565	COG1131	(ABC) transporter
BLMD_RS20585	COG1595	DNA-templated transcription, initiation
BLMD_RS20590	COG2814	Major facilitator Superfamily
BLMD_RS20600	COG0753	catalase activity
BLMD_RS20605	COG0753	catalase activity
BLMD_RS20610	COG0735	belongs to the Fur family
BLMD_RS20615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BLMD_RS20625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLMD_RS20630	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BLMD_RS20635	COG4988	ABC transporter
BLMD_RS20640	COG1294	oxidase, subunit
BLMD_RS20645	COG1271	oxidase subunit
BLMD_RS20655	COG2116	formate transmembrane transporter activity
BLMD_RS20665	COG0281	malic enzyme
BLMD_RS20670	COG1757	Na H antiporter
BLMD_RS20675	COG1027	Aspartate ammonia-lyase
BLMD_RS20680	COG0252	asparaginase activity
BLMD_RS20685	COG1396	sequence-specific DNA binding
BLMD_RS20690	COG2706	6-phosphogluconolactonase activity
BLMD_RS20695	COG0745	RESPONSE REGULATOR receiver
BLMD_RS20700	COG2205	protein histidine kinase activity
BLMD_RS20705	COG1136	(ABC) transporter
BLMD_RS20710	COG0577	efflux transmembrane transporter activity
BLMD_RS20715	COG5294	Protein conserved in bacteria
BLMD_RS20730	COG0726	polysaccharide deacetylase
BLMD_RS20735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLMD_RS20745	COG1215	transferase activity, transferring glycosyl groups
BLMD_RS20750	COG3493	citrate carrier protein
BLMD_RS20755	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_RS20770	COG1368	sulfuric ester hydrolase activity
BLMD_RS20780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BLMD_RS20795	COG2235	arginine
BLMD_RS20800	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLMD_RS20810	COG0549	Belongs to the carbamate kinase family
BLMD_RS20820	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS20825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BLMD_RS20835	COG1595	DNA-templated transcription, initiation
BLMD_RS20845	COG2195	Cleaves the N-terminal amino acid of tripeptides
BLMD_RS20855	COG2223	nitrite transmembrane transporter activity
BLMD_RS20860	COG0395	ABC-type sugar transport system, permease component
BLMD_RS20865	COG1175	transmembrane transport
BLMD_RS20875	COG1609	Transcriptional regulator
BLMD_RS20890	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLMD_RS20895	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLMD_RS20900	COG0463	Glycosyl transferase, family 2
BLMD_RS20905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_RS20935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_RS20945	COG0753	catalase activity
BLMD_RS20945	COG0693	protein deglycase activity
BLMD_RS20955	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS20960	COG2190	(PTS) system
BLMD_RS20960	COG1263	PTS System
BLMD_RS20960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS20965	COG3711	transcriptional antiterminator
BLMD_RS20970	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLMD_RS20975	COG1122	ATPase activity
BLMD_RS20980	COG4721	ABC-type cobalt transport system, permease component
BLMD_RS20985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLMD_RS20990	COG2224	Isocitrate lyase
BLMD_RS20995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BLMD_RS21005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BLMD_RS21010	COG0577	efflux transmembrane transporter activity
BLMD_RS21015	COG1136	(ABC) transporter
BLMD_RS21020	COG2205	protein histidine kinase activity
BLMD_RS21025	COG0745	RESPONSE REGULATOR receiver
BLMD_RS21030	COG2723	6-phospho-beta-galactosidase activity
BLMD_RS21035	COG1263	PTS System
BLMD_RS21035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS21035	COG2190	(PTS) system
BLMD_RS21045	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BLMD_RS21050	COG3507	Belongs to the glycosyl hydrolase 43 family
BLMD_RS21055	COG0513	Belongs to the DEAD box helicase family
BLMD_RS21100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BLMD_RS21105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BLMD_RS21110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BLMD_RS21115	COG2390	Transcriptional regulator
BLMD_RS21120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BLMD_RS21125	COG3706	GGDEF domain
BLMD_RS21130	COG5298	Protein conserved in bacteria
BLMD_RS21135	COG1215	transferase activity, transferring glycosyl groups
BLMD_RS21145	COG3977	Valine--pyruvate aminotransferase
BLMD_RS21160	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLMD_RS21170	COG0191	fructose-bisphosphate aldolase activity
BLMD_RS21175	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_RS21180	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_RS21185	COG0673	inositol 2-dehydrogenase activity
BLMD_RS21190	COG2814	Major facilitator Superfamily
BLMD_RS21195	COG1082	Xylose isomerase domain protein TIM barrel
BLMD_RS21200	COG3962	Belongs to the TPP enzyme family
BLMD_RS21205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLMD_RS21210	COG3718	enzyme involved in inositol metabolism
BLMD_RS21215	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS21220	COG1349	DNA-binding transcription factor activity
BLMD_RS21225	COG0667	Aldo Keto reductase
BLMD_RS21230	COG0584	glycerophosphoryl diester phosphodiesterase
BLMD_RS21235	COG2271	Major facilitator Superfamily
BLMD_RS21240	COG0326	Molecular chaperone. Has ATPase activity
BLMD_RS21245	COG0488	(ABC) transporter
BLMD_RS21250	COG0561	phosphatase activity
BLMD_RS21270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS21300	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
BLMD_RS21305	COG0577	efflux transmembrane transporter activity
BLMD_RS21310	COG1136	(ABC) transporter
BLMD_RS21315	COG2205	protein histidine kinase activity
BLMD_RS21320	COG0745	RESPONSE REGULATOR receiver
BLMD_RS21330	COG5278	phosphoserine phosphatase activity
BLMD_RS21330	COG0840	transmembrane signaling receptor activity
BLMD_RS21335	COG1115	amino acid carrier protein
BLMD_RS21340	COG0686	Belongs to the AlaDH PNT family
BLMD_RS21345	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BLMD_RS21350	COG1874	Beta-galactosidase
BLMD_RS21355	COG3833	ABC-type maltose transport systems, permease component
BLMD_RS21360	COG1175	transmembrane transport
BLMD_RS21365	COG2182	Extracellular solute-binding protein
BLMD_RS21370	COG1609	Transcriptional regulator
BLMD_RS21375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLMD_RS21380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLMD_RS21385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BLMD_RS21390	COG1940	carbohydrate kinase activity
BLMD_RS21400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLMD_RS21430	COG1012	belongs to the aldehyde dehydrogenase family
BLMD_RS21430	COG1454	alcohol dehydrogenase
BLMD_RS21435	COG0450	alkyl hydroperoxide reductase
BLMD_RS21440	COG3634	alkyl hydroperoxide reductase activity
BLMD_RS21445	COG1113	amino acid transport
BLMD_RS21465	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
BLMD_RS21475	COG2205	protein histidine kinase activity
BLMD_RS21485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BLMD_RS21490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS21495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLMD_RS21510	COG1131	(ABC) transporter
BLMD_RS21515	COG0842	Transport permease protein
BLMD_RS21520	COG4585	Histidine kinase
BLMD_RS21525	COG2197	response regulator
BLMD_RS21530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLMD_RS21540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLMD_RS21555	COG0456	acetyltransferase
BLMD_RS21570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLMD_RS21575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLMD_RS21580	COG4853	Protein conserved in bacteria
BLMD_RS21585	COG4863	YycH protein
BLMD_RS21590	COG5002	protein histidine kinase activity
BLMD_RS21595	COG0745	RESPONSE REGULATOR receiver
BLMD_RS21625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLMD_RS21635	COG0305	Participates in initiation and elongation during chromosome replication
BLMD_RS21650	COG3093	addiction module antidote protein HigA
BLMD_RS21655	COG2807	transmembrane transport
BLMD_RS21660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BLMD_RS21665	COG0363	glucosamine-6-phosphate deaminase activity
BLMD_RS21670	COG2188	Transcriptional regulator
BLMD_RS21675	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BLMD_RS21680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLMD_RS21680	COG1263	PTS System
BLMD_RS21685	COG0359	binds to the 23S rRNA
BLMD_RS21690	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BLMD_RS21695	COG4241	membrane
BLMD_RS21700	COG5577	PFAM Coat F domain
BLMD_RS21705	COG0589	response to stress
BLMD_RS21710	COG0659	secondary active sulfate transmembrane transporter activity
BLMD_RS21715	COG2271	Major facilitator Superfamily
BLMD_RS21720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLMD_RS21725	COG0629	single-stranded DNA binding
BLMD_RS21730	COG0360	Binds together with S18 to 16S ribosomal RNA
BLMD_RS21735	COG0012	GTP binding
BLMD_RS21745	COG4481	Protein conserved in bacteria
BLMD_RS21750	COG3949	Membrane
BLMD_RS21760	COG1475	DNA binding
BLMD_RS21765	COG1192	Involved in chromosome partitioning
BLMD_RS21770	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLMD_RS21775	COG1595	DNA-templated transcription, initiation
BLMD_RS21780	COG1475	DNA binding
BLMD_RS21785	COG0357	Ribosomal RNA small subunit methyltransferase G
BLMD_RS21790	COG0445	tRNA wobble uridine modification
BLMD_RS21795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLMD_RS21800	COG1847	R3H domain protein
BLMD_RS21805	COG0706	membrane insertase activity
BLMD_RS21810	COG0594	ribonuclease P activity