locus-tag	class	description
LIS80_RS00010	COG0592	DNA-directed DNA polymerase activity
LIS80_RS00015	COG2501	S4 domain
LIS80_RS00025	COG0187	DNA topoisomerase II activity
LIS80_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIS80_RS00065	COG0516	GMP reductase activity
LIS80_RS00065	COG0517	IMP dehydrogenase activity
LIS80_RS00070	COG1686	Belongs to the peptidase S11 family
LIS80_RS00100	COG1428	Deoxynucleoside kinase
LIS80_RS00105	COG1428	Deoxynucleoside kinase
LIS80_RS00110	COG1335	isochorismatase
LIS80_RS00115	COG0590	tRNA wobble adenosine to inosine editing
LIS80_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LIS80_RS00180	COG1982	Orn Lys Arg decarboxylase major
LIS80_RS00190	COG0470	DNA polymerase III
LIS80_RS00195	COG1774	PSP1 C-terminal conserved region
LIS80_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LIS80_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LIS80_RS00220	COG2002	toxin-antitoxin pair type II binding
LIS80_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_RS00230	COG0084	hydrolase, TatD family'
LIS80_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LIS80_RS00250	COG4466	Protein conserved in bacteria
LIS80_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LIS80_RS00270	COG0251	oxidation-reduction process
LIS80_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LIS80_RS00305	COG2002	toxin-antitoxin pair type II binding
LIS80_RS00310	COG2244	polysaccharide biosynthetic process
LIS80_RS00315	COG3956	TIGRFAM MazG family protein
LIS80_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LIS80_RS00340	COG1098	S1 RNA binding domain
LIS80_RS00355	COG2208	phosphoserine phosphatase activity
LIS80_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIS80_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LIS80_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LIS80_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
LIS80_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LIS80_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LIS80_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LIS80_RS00420	COG1396	sequence-specific DNA binding
LIS80_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIS80_RS00515	COG3880	PFAM UvrB UvrC protein
LIS80_RS00525	COG0542	response to heat
LIS80_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LIS80_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
LIS80_RS00560	COG1045	serine acetyltransferase
LIS80_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIS80_RS00580	COG3688	RNA-binding protein containing a PIN domain
LIS80_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIS80_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
LIS80_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LIS80_RS00625	COG2813	Specifically methylates the guanine in position
LIS80_RS00640	COG1358	cellular component organization or biogenesis
LIS80_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
LIS80_RS00770	COG0201	protein transport
LIS80_RS00780	COG0024	Methionine aminopeptidase
LIS80_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LIS80_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LIS80_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIS80_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS00855	COG0489	protein tyrosine kinase activity
LIS80_RS00865	COG2194	sulfuric ester hydrolase activity
LIS80_RS00870	COG0726	polysaccharide deacetylase
LIS80_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LIS80_RS00955	COG4856	YbbR-like protein
LIS80_RS00975	COG0596	Alpha beta hydrolase
LIS80_RS00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LIS80_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS01035	COG2011	ABC-type metal ion transport system permease component
LIS80_RS01045	COG1464	Belongs to the NlpA lipoprotein family
LIS80_RS01050	COG0604	alcohol dehydrogenase
LIS80_RS01060	COG0277	FAD linked oxidase domain protein
LIS80_RS01065	COG2271	Major facilitator Superfamily
LIS80_RS01075	COG2814	Major facilitator Superfamily
LIS80_RS01095	COG0601	transmembrane transport
LIS80_RS01100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_RS01105	COG0444	Belongs to the ABC transporter superfamily
LIS80_RS01110	COG4608	Belongs to the ABC transporter superfamily
LIS80_RS01115	COG4166	transmembrane transport
LIS80_RS01125	COG2207	Transcriptional regulator
LIS80_RS01135	COG1309	transcriptional regulator
LIS80_RS01145	COG4166	transmembrane transport
LIS80_RS01150	COG4166	transmembrane transport
LIS80_RS01155	COG0656	L-ascorbic acid biosynthetic process
LIS80_RS01160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_RS01175	COG4149	molybdate abc transporter
LIS80_RS01180	COG0725	ABC transporter, periplasmic molybdate-binding protein
LIS80_RS01185	COG1910	domain protein
LIS80_RS01200	COG0697	spore germination
LIS80_RS01215	COG0204	Acyl-transferase
LIS80_RS01225	COG1609	Transcriptional regulator
LIS80_RS01235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS01245	COG0084	hydrolase, TatD family'
LIS80_RS01250	COG5298	Protein conserved in bacteria
LIS80_RS01275	COG0488	(ABC) transporter
LIS80_RS01285	COG0747	negative chemotaxis
LIS80_RS01290	COG0747	negative chemotaxis
LIS80_RS01295	COG0601	transmembrane transport
LIS80_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_RS01305	COG0444	Belongs to the ABC transporter superfamily
LIS80_RS01310	COG4608	Belongs to the ABC transporter superfamily
LIS80_RS01315	COG0561	phosphatase activity
LIS80_RS01345	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LIS80_RS01350	COG0179	Fumarylacetoacetate (FAA) hydrolase
LIS80_RS01360	COG0531	amino acid
LIS80_RS01365	COG2814	Major facilitator Superfamily
LIS80_RS01375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LIS80_RS01385	COG4294	response to UV
LIS80_RS01390	COG0705	Rhomboid family
LIS80_RS01400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LIS80_RS01405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LIS80_RS01410	COG0864	Transcriptional regulator
LIS80_RS01415	COG2337	Toxic component of a toxin-antitoxin (TA) module
LIS80_RS01420	COG2183	response to ionizing radiation
LIS80_RS01515	COG0802	atpase or kinase
LIS80_RS01520	COG1214	PFAM Peptidase M22, glycoprotease
LIS80_RS01525	COG0456	acetyltransferase
LIS80_RS01535	COG0488	(ABC) transporter
LIS80_RS01550	COG1266	CAAX protease self-immunity
LIS80_RS01570	COG2252	PERMEase
LIS80_RS01580	COG5002	protein histidine kinase activity
LIS80_RS01635	COG2226	methyltransferase
LIS80_RS01655	COG1215	transferase activity, transferring glycosyl groups
LIS80_RS01675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS01680	COG0506	proline dehydrogenase activity
LIS80_RS01705	COG0697	spore germination
LIS80_RS01735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LIS80_RS01740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LIS80_RS01745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LIS80_RS01755	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LIS80_RS01770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LIS80_RS01780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LIS80_RS01790	COG0151	Belongs to the GarS family
LIS80_RS01815	COG0210	DNA helicase
LIS80_RS01825	COG4851	CamS sex pheromone cAM373 precursor
LIS80_RS01845	COG1335	isochorismatase
LIS80_RS01855	COG2011	ABC-type metal ion transport system permease component
LIS80_RS01860	COG1464	Belongs to the NlpA lipoprotein family
LIS80_RS01875	COG0003	Pfam Anion-transporting ATPase
LIS80_RS01880	COG1846	Transcriptional regulator
LIS80_RS01885	COG4682	membrane
LIS80_RS01905	COG1597	lipid kinase activity
LIS80_RS01910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LIS80_RS01915	COG0546	phosphoglycolate phosphatase activity
LIS80_RS01920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LIS80_RS01930	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS01935	COG2076	Multidrug Resistance protein
LIS80_RS01940	COG2309	aminopeptidase activity
LIS80_RS01950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS01960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LIS80_RS01970	COG0028	Belongs to the TPP enzyme family
LIS80_RS01980	COG4807	Protein conserved in bacteria
LIS80_RS02005	COG0673	inositol 2-dehydrogenase activity
LIS80_RS02010	COG0277	FAD linked oxidase domain protein
LIS80_RS02020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_RS02040	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LIS80_RS02045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIS80_RS02055	COG2814	Major facilitator Superfamily
LIS80_RS02065	COG4807	Protein conserved in bacteria
LIS80_RS02090	COG1757	Na H antiporter
LIS80_RS02095	COG1473	amidohydrolase
LIS80_RS02110	COG0450	alkyl hydroperoxide reductase
LIS80_RS02140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS02145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS02150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS02165	COG0166	Belongs to the GPI family
LIS80_RS02205	COG3541	Predicted nucleotidyltransferase
LIS80_RS02210	COG2814	Major facilitator Superfamily
LIS80_RS02215	COG0723	plastoquinol--plastocyanin reductase activity
LIS80_RS02215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_RS02240	COG0765	amino acid transport
LIS80_RS02245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS02255	COG0840	transmembrane signaling receptor activity
LIS80_RS02260	COG0366	Alpha amylase catalytic
LIS80_RS02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_RS02265	COG2190	(PTS) system
LIS80_RS02265	COG1263	PTS System
LIS80_RS02285	COG1695	Transcriptional regulator
LIS80_RS02295	COG0577	efflux transmembrane transporter activity
LIS80_RS02300	COG1136	(ABC) transporter
LIS80_RS02325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LIS80_RS02355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LIS80_RS02370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_RS02380	COG1116	anion transmembrane transporter activity
LIS80_RS02390	COG0488	(ABC) transporter
LIS80_RS02440	COG2270	Major facilitator Superfamily
LIS80_RS02470	COG2310	stress, protein
LIS80_RS02475	COG2310	stress, protein
LIS80_RS02480	COG2310	stress, protein
LIS80_RS02485	COG0861	Integral membrane protein TerC family
LIS80_RS02495	COG3853	Toxic anion resistance protein (TelA)
LIS80_RS02510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LIS80_RS02520	COG1295	ribonuclease BN
LIS80_RS02525	COG2217	Heavy metal translocating P-type atpase
LIS80_RS02530	COG0697	spore germination
LIS80_RS02545	COG0681	Belongs to the peptidase S26 family
LIS80_RS02555	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS02570	COG3871	stress protein (general stress protein 26)
LIS80_RS02575	COG0387	Pfam Sodium calcium exchanger
LIS80_RS02585	COG0535	radical SAM domain protein
LIS80_RS02605	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LIS80_RS02635	COG3829	transcription factor binding
LIS80_RS02645	COG0833	amino acid
LIS80_RS02650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_RS02680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_RS02680	COG1263	PTS System
LIS80_RS02685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_RS02700	COG0463	Glycosyl transferase, family 2
LIS80_RS02710	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIS80_RS02710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIS80_RS02725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LIS80_RS02745	COG0402	S-adenosylhomocysteine deaminase activity
LIS80_RS02750	COG1090	epimerase
LIS80_RS02780	COG1988	membrane-bound metal-dependent
LIS80_RS02785	COG1194	a g-specific adenine glycosylase
LIS80_RS02810	COG1132	(ABC) transporter
LIS80_RS02815	COG4129	membrane
LIS80_RS02820	COG0067	glutamate synthase
LIS80_RS02820	COG0069	glutamate synthase activity
LIS80_RS02820	COG0070	glutamate synthase
LIS80_RS02830	COG4555	ABC transporter
LIS80_RS02850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LIS80_RS02855	COG0735	belongs to the Fur family
LIS80_RS02965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LIS80_RS02985	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LIS80_RS02995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LIS80_RS03005	COG2766	serine protein kinase
LIS80_RS03025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_RS03035	COG1585	Membrane protein implicated in regulation of membrane protease activity
LIS80_RS03040	COG2268	Band 7 protein
LIS80_RS03050	COG3290	protein histidine kinase activity
LIS80_RS03055	COG4565	transcriptional regulatory protein
LIS80_RS03060	COG2851	Citrate transporter
LIS80_RS03085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LIS80_RS03090	COG3842	ATPase activity
LIS80_RS03095	COG1175	transmembrane transport
LIS80_RS03100	COG0395	ABC-type sugar transport system, permease component
LIS80_RS03110	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LIS80_RS03115	COG0745	RESPONSE REGULATOR receiver
LIS80_RS03120	COG5002	protein histidine kinase activity
LIS80_RS03130	COG4990	cell redox homeostasis
LIS80_RS03140	COG3290	protein histidine kinase activity
LIS80_RS03145	COG4565	transcriptional regulatory protein
LIS80_RS03150	COG3493	citrate carrier protein
LIS80_RS03155	COG0281	malic enzyme
LIS80_RS03165	COG0697	spore germination
LIS80_RS03170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS03180	COG5002	protein histidine kinase activity
LIS80_RS03185	COG0745	RESPONSE REGULATOR receiver
LIS80_RS03190	COG0456	acetyltransferase
LIS80_RS03190	COG0454	-acetyltransferase
LIS80_RS03195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LIS80_RS03200	COG3383	formate dehydrogenase (NAD+) activity
LIS80_RS03205	COG2427	Protein of unknown function (DUF1641)
LIS80_RS03220	COG0531	amino acid
LIS80_RS03225	COG0640	Transcriptional regulator
LIS80_RS03230	COG2217	Heavy metal translocating P-type atpase
LIS80_RS03235	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LIS80_RS03250	COG3227	Zinc metalloprotease (Elastase)
LIS80_RS03270	COG2720	vancomycin resistance protein
LIS80_RS03275	COG1316	TRANSCRIPTIONal
LIS80_RS03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS03285	COG0346	lactoylglutathione lyase activity
LIS80_RS03290	COG1253	flavin adenine dinucleotide binding
LIS80_RS03295	COG1027	Aspartate ammonia-lyase
LIS80_RS03305	COG1620	l-lactate permease
LIS80_RS03320	COG3104	oligopeptide transport
LIS80_RS03325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS03330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS03345	COG2226	methyltransferase
LIS80_RS03350	COG0156	8-amino-7-oxononanoate synthase activity
LIS80_RS03355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LIS80_RS03360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LIS80_RS03370	COG4548	von Willebrand factor, type A
LIS80_RS03375	COG0714	Associated with various cellular activities
LIS80_RS03380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS03400	COG0531	amino acid
LIS80_RS03405	COG2188	Transcriptional regulator
LIS80_RS03410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_RS03410	COG1263	PTS System
LIS80_RS03415	COG0366	Alpha amylase catalytic
LIS80_RS03430	COG0697	spore germination
LIS80_RS03440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LIS80_RS03445	COG1115	amino acid carrier protein
LIS80_RS03450	COG1126	abc transporter atp-binding protein
LIS80_RS03455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS03460	COG0765	amino acid transport
LIS80_RS03465	COG0765	amino acid transport
LIS80_RS03470	COG0833	amino acid
LIS80_RS03495	COG2378	regulation of single-species biofilm formation
LIS80_RS03500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIS80_RS03505	COG5002	protein histidine kinase activity
LIS80_RS03520	COG0659	secondary active sulfate transmembrane transporter activity
LIS80_RS03545	COG0601	transmembrane transport
LIS80_RS03550	COG4608	Belongs to the ABC transporter superfamily
LIS80_RS03560	COG2271	Major facilitator Superfamily
LIS80_RS03565	COG1846	Transcriptional regulator
LIS80_RS03570	COG0477	Major facilitator Superfamily
LIS80_RS03575	COG1609	Transcriptional regulator
LIS80_RS03580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LIS80_RS03595	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS03600	COG1879	ABC-type sugar transport system periplasmic component
LIS80_RS03625	COG1063	alcohol dehydrogenase
LIS80_RS03645	COG3568	Endonuclease Exonuclease Phosphatase
LIS80_RS03675	COG0840	transmembrane signaling receptor activity
LIS80_RS03680	COG3583	domain protein
LIS80_RS03680	COG3584	3D domain protein
LIS80_RS03685	COG1476	TRANSCRIPTIONal
LIS80_RS03705	COG3104	oligopeptide transport
LIS80_RS03710	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS03725	COG1113	amino acid transport
LIS80_RS03730	COG2252	PERMEase
LIS80_RS03745	COG2153	protein acetylation
LIS80_RS03755	COG0475	glutathione-regulated potassium exporter activity
LIS80_RS03755	COG0569	domain protein
LIS80_RS03770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LIS80_RS03775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LIS80_RS03780	COG0833	amino acid
LIS80_RS03785	COG4990	cell redox homeostasis
LIS80_RS03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_RS03805	COG0697	spore germination
LIS80_RS03810	COG0531	amino acid
LIS80_RS03825	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_RS03830	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_RS03835	COG1918	ferrous iron import across plasma membrane
LIS80_RS03835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LIS80_RS03840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LIS80_RS03845	COG0573	inorganic phosphate transmembrane transporter activity
LIS80_RS03850	COG0581	inorganic phosphate transmembrane transporter activity
LIS80_RS03855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIS80_RS03975	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LIS80_RS03995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LIS80_RS04000	COG1116	anion transmembrane transporter activity
LIS80_RS04005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_RS04010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_RS04015	COG0352	thiamine-phosphate diphosphorylase activity
LIS80_RS04020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_RS04025	COG2104	thiamine diphosphate biosynthetic process
LIS80_RS04035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_RS04040	COG0351	phosphomethylpyrimidine kinase
LIS80_RS04080	COG2205	protein histidine kinase activity
LIS80_RS04085	COG2814	Major facilitator Superfamily
LIS80_RS04090	COG1846	Transcriptional regulator
LIS80_RS04115	COG1136	(ABC) transporter
LIS80_RS04125	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS04130	COG1129	ABC transporter
LIS80_RS04140	COG2252	PERMEase
LIS80_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS04165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS04205	COG0778	Nitroreductase
LIS80_RS04210	COG2719	SpoVR family
LIS80_RS04230	COG0446	pyridine nucleotide-disulphide oxidoreductase
LIS80_RS04235	COG1937	Protein conserved in bacteria
LIS80_RS04240	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_RS04240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_RS04245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_RS04245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS04250	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_RS04255	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_RS04260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_RS04260	COG0425	Belongs to the sulfur carrier protein TusA family
LIS80_RS04270	COG2210	Belongs to the sulfur carrier protein TusA family
LIS80_RS04275	COG0730	response to heat
LIS80_RS04285	COG1316	TRANSCRIPTIONal
LIS80_RS04290	COG0604	alcohol dehydrogenase
LIS80_RS04295	COG1283	sodium-dependent phosphate transmembrane transporter activity
LIS80_RS04300	COG2814	Major facilitator Superfamily
LIS80_RS04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS04310	COG3711	transcriptional antiterminator
LIS80_RS04315	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_RS04320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_RS04345	COG1388	LysM domain
LIS80_RS04345	COG3584	3D domain protein
LIS80_RS04350	COG0577	efflux transmembrane transporter activity
LIS80_RS04355	COG1136	(ABC) transporter
LIS80_RS04365	COG5522	Integral membrane protein (intg_mem_TP0381)
LIS80_RS04380	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS04385	COG3546	catalase activity
LIS80_RS04420	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS04455	COG0531	amino acid
LIS80_RS04460	COG0475	glutathione-regulated potassium exporter activity
LIS80_RS04470	COG1737	Transcriptional regulator
LIS80_RS04480	COG1263	PTS System
LIS80_RS04480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_RS04490	COG2259	Doxx family
LIS80_RS04495	COG3631	Ketosteroid isomerase-related protein
LIS80_RS04510	COG1522	sequence-specific DNA binding
LIS80_RS04525	COG2076	Multidrug Resistance protein
LIS80_RS04530	COG1309	transcriptional regulator
LIS80_RS04535	COG2814	Major facilitator Superfamily
LIS80_RS04540	COG1733	regulation of RNA biosynthetic process
LIS80_RS04550	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS04555	COG4533	DNA binding
LIS80_RS04560	COG2211	Major facilitator Superfamily
LIS80_RS04570	COG0693	protein deglycase activity
LIS80_RS04575	COG0753	catalase activity
LIS80_RS04585	COG0531	amino acid
LIS80_RS04590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LIS80_RS04600	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS04605	COG1132	(ABC) transporter
LIS80_RS04610	COG1132	(ABC) transporter
LIS80_RS04615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS04620	COG0765	amino acid transport
LIS80_RS04625	COG1126	abc transporter atp-binding protein
LIS80_RS04640	COG0189	ligase activity
LIS80_RS04665	COG4585	Histidine kinase
LIS80_RS04670	COG2197	response regulator
LIS80_RS04710	COG0028	Belongs to the TPP enzyme family
LIS80_RS04715	COG3527	Alpha-acetolactate decarboxylase
LIS80_RS04725	COG0561	phosphatase activity
LIS80_RS04730	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS04730	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_RS04735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIS80_RS04755	COG0659	secondary active sulfate transmembrane transporter activity
LIS80_RS04770	COG0653	protein targeting
LIS80_RS04775	COG2244	polysaccharide biosynthetic process
LIS80_RS04805	COG1696	Membrane protein involved in D-alanine export
LIS80_RS04820	COG1024	Enoyl-CoA hydratase
LIS80_RS04840	COG1363	Peptidase, m42
LIS80_RS04885	COG0601	transmembrane transport
LIS80_RS04890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_RS04895	COG0444	Belongs to the ABC transporter superfamily
LIS80_RS04900	COG4608	Belongs to the ABC transporter superfamily
LIS80_RS04905	COG0477	Major facilitator Superfamily
LIS80_RS04910	COG3290	protein histidine kinase activity
LIS80_RS04915	COG4565	transcriptional regulatory protein
LIS80_RS04920	COG3181	Tripartite tricarboxylate transporter family receptor
LIS80_RS04985	COG4978	Transcriptional regulator
LIS80_RS04985	COG0789	Transcriptional regulator
LIS80_RS05020	COG0305	Participates in initiation and elongation during chromosome replication
LIS80_RS05115	COG1183	phosphatidylcholine synthase activity
LIS80_RS05130	COG2376	Dihydroxyacetone kinase
LIS80_RS05140	COG2376	Dihydroxyacetone kinase
LIS80_RS05165	COG2770	Histidine kinase
LIS80_RS05165	COG3437	response regulator, receiver
LIS80_RS05255	COG3237	CsbD-like
LIS80_RS05280	COG1191	sigma factor activity
LIS80_RS05290	COG2208	phosphoserine phosphatase activity
LIS80_RS05295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LIS80_RS05300	COG2205	protein histidine kinase activity
LIS80_RS05300	COG2198	Histidine kinase
LIS80_RS05300	COG0784	Response regulator, receiver
LIS80_RS05375	COG0420	3'-5' exonuclease activity
LIS80_RS05380	COG4717	serine-type aminopeptidase activity
LIS80_RS05390	COG1309	transcriptional regulator
LIS80_RS05395	COG2814	Major facilitator Superfamily
LIS80_RS05400	COG0346	lactoylglutathione lyase activity
LIS80_RS05405	COG0346	lactoylglutathione lyase activity
LIS80_RS05415	COG2267	carboxylic ester hydrolase activity
LIS80_RS05445	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LIS80_RS05450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LIS80_RS05460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LIS80_RS05475	COG1595	DNA-templated transcription, initiation
LIS80_RS05485	COG0772	Belongs to the SEDS family
LIS80_RS05515	COG3973	AAA domain
LIS80_RS05520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_RS05540	COG4980	gas vesicle protein
LIS80_RS05545	COG0537	adenosine 5'-monophosphoramidase activity
LIS80_RS05550	COG1131	(ABC) transporter
LIS80_RS05555	COG4473	ABC transporter
LIS80_RS05570	COG1309	transcriptional regulator
LIS80_RS05580	COG3402	PFAM membrane-flanked domain
LIS80_RS05585	COG3428	Bacterial PH domain
LIS80_RS05615	COG3402	PFAM membrane-flanked domain
LIS80_RS05620	COG3428	Bacterial PH domain
LIS80_RS05625	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_RS05630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_RS05645	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LIS80_RS05675	COG1309	transcriptional regulator
LIS80_RS05680	COG1511	domain protein
LIS80_RS05710	COG2378	regulation of single-species biofilm formation
LIS80_RS05715	COG1609	Transcriptional regulator
LIS80_RS05725	COG1234	tRNA 3'-trailer cleavage
LIS80_RS05730	COG0095	Lipoate-protein ligase
LIS80_RS05740	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_RS05820	COG1073	alpha beta
LIS80_RS05825	COG1408	metallophosphoesterase
LIS80_RS05835	COG1078	dGTPase activity
LIS80_RS05845	COG1595	DNA-templated transcription, initiation
LIS80_RS05850	COG3708	Transcriptional regulator
LIS80_RS05850	COG2207	Transcriptional regulator
LIS80_RS05865	COG2205	protein histidine kinase activity
LIS80_RS05870	COG0745	RESPONSE REGULATOR receiver
LIS80_RS05895	COG0501	Belongs to the peptidase M48B family
LIS80_RS05900	COG0697	spore germination
LIS80_RS05920	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LIS80_RS05925	COG2224	Isocitrate lyase
LIS80_RS05935	COG1278	Cold shock
LIS80_RS05950	COG4903	ComK protein
LIS80_RS05960	COG0398	Pfam SNARE associated Golgi protein
LIS80_RS06020	COG0179	Fumarylacetoacetate (FAA) hydrolase
LIS80_RS06045	COG0367	asparagine synthase
LIS80_RS06050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LIS80_RS06055	COG0753	catalase activity
LIS80_RS06060	COG0004	ammonium transporteR
LIS80_RS06080	COG2996	Protein conserved in bacteria
LIS80_RS06085	COG3209	COG3209 Rhs family protein
LIS80_RS06110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_RS06120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS06135	COG0561	phosphatase activity
LIS80_RS06160	COG2267	carboxylic ester hydrolase activity
LIS80_RS06175	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_RS06180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LIS80_RS06185	COG5504	Zn-dependent protease
LIS80_RS06195	COG0180	Tryptophanyl-tRNA synthetase
LIS80_RS06205	COG4166	transmembrane transport
LIS80_RS06210	COG0601	transmembrane transport
LIS80_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LIS80_RS06220	COG0444	Belongs to the ABC transporter superfamily
LIS80_RS06225	COG4608	Belongs to the ABC transporter superfamily
LIS80_RS06230	COG0534	Mate efflux family protein
LIS80_RS06235	COG4166	transmembrane transport
LIS80_RS06250	COG0861	Integral membrane protein TerC family
LIS80_RS06255	COG4862	establishment of competence for transformation
LIS80_RS06260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS06270	COG1164	Oligoendopeptidase f
LIS80_RS06285	COG2346	COG2346, Truncated hemoglobins
LIS80_RS06290	COG4116	CYTH
LIS80_RS06300	COG2357	RelA SpoT domain protein
LIS80_RS06310	COG0564	pseudouridine synthase activity
LIS80_RS06325	COG0772	Belongs to the SEDS family
LIS80_RS06330	COG1216	Glycosyl transferase, family 2
LIS80_RS06330	COG0463	Glycosyl transferase, family 2
LIS80_RS06350	COG0463	Glycosyl transferase, family 2
LIS80_RS06350	COG0457	Tetratricopeptide repeat
LIS80_RS06370	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LIS80_RS06385	COG1091	dTDP-4-dehydrorhamnose reductase activity
LIS80_RS06430	COG2153	protein acetylation
LIS80_RS06440	COG2382	esterase
LIS80_RS06455	COG5492	domain, Protein
LIS80_RS06460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_RS06470	COG0512	Glutamine amidotransferase of anthranilate synthase
LIS80_RS06470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LIS80_RS06505	COG1620	l-lactate permease
LIS80_RS06510	COG5634	Uncharacterized conserved protein (DUF2278)
LIS80_RS06515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS06585	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_RS06595	COG1476	TRANSCRIPTIONal
LIS80_RS06695	COG0582	viral genome integration into host DNA
LIS80_RS06710	COG2226	methyltransferase
LIS80_RS06720	COG1686	Belongs to the peptidase S11 family
LIS80_RS06725	COG0681	Belongs to the peptidase S26 family
LIS80_RS06760	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS06770	COG1176	ABC-type spermidine putrescine transport system, permease component I
LIS80_RS06775	COG1177	transmembrane transport
LIS80_RS06780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LIS80_RS06790	COG2409	Drug exporters of the RND superfamily
LIS80_RS06800	COG0564	pseudouridine synthase activity
LIS80_RS06810	COG2340	Cysteine-rich secretory protein family
LIS80_RS06815	COG0247	lactate metabolic process
LIS80_RS06820	COG0277	FAD linked oxidase domain protein
LIS80_RS06825	COG3835	regulator
LIS80_RS06835	COG0745	RESPONSE REGULATOR receiver
LIS80_RS06840	COG5002	protein histidine kinase activity
LIS80_RS06845	COG2186	Transcriptional regulator
LIS80_RS06865	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LIS80_RS06875	COG2116	formate transmembrane transporter activity
LIS80_RS06880	COG0861	Integral membrane protein TerC family
LIS80_RS06885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_RS06895	COG2030	dehydratase
LIS80_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS06920	COG3243	poly(R)-hydroxyalkanoic acid synthase
LIS80_RS06930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_RS06945	COG1840	ABC-type Fe3 transport system, periplasmic component
LIS80_RS06950	COG3842	ATPase activity
LIS80_RS06975	COG1349	DNA-binding transcription factor activity
LIS80_RS06985	COG0235	Class ii aldolase
LIS80_RS06995	COG2861	carbohydrate metabolic process
LIS80_RS07005	COG3852	Histidine kinase
LIS80_RS07010	COG1846	Transcriptional regulator
LIS80_RS07020	COG2318	DinB family
LIS80_RS07030	COG5002	protein histidine kinase activity
LIS80_RS07040	COG0720	synthase
LIS80_RS07055	COG4873	Protein conserved in bacteria
LIS80_RS07085	COG1780	Probably involved in ribonucleotide reductase function
LIS80_RS07115	COG1725	Transcriptional regulator
LIS80_RS07120	COG1131	(ABC) transporter
LIS80_RS07130	COG1131	(ABC) transporter
LIS80_RS07135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_RS07140	COG1266	CAAX protease self-immunity
LIS80_RS07150	COG1522	sequence-specific DNA binding
LIS80_RS07160	COG1335	isochorismatase
LIS80_RS07170	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_RS07175	COG2070	2-Nitropropane dioxygenase
LIS80_RS07180	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LIS80_RS07190	COG1696	Membrane protein involved in D-alanine export
LIS80_RS07215	COG0716	FMN binding
LIS80_RS07230	COG3173	Aminoglycoside phosphotransferase
LIS80_RS07250	COG0534	Mate efflux family protein
LIS80_RS07270	COG1846	Transcriptional regulator
LIS80_RS07280	COG1301	dicarboxylic acid transport
LIS80_RS07285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LIS80_RS07290	COG4709	membrane
LIS80_RS07295	COG3874	Sporulation protein YtfJ
LIS80_RS07315	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_RS07320	COG0028	Belongs to the TPP enzyme family
LIS80_RS07325	COG0440	acetolactate synthase activity
LIS80_RS07400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LIS80_RS07415	COG1183	phosphatidylcholine synthase activity
LIS80_RS07420	COG1368	sulfuric ester hydrolase activity
LIS80_RS07430	COG0019	diaminopimelate decarboxylase activity
LIS80_RS07450	COG0529	Catalyzes the synthesis of activated sulfate
LIS80_RS07455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LIS80_RS07475	COG1648	precorrin-2 dehydrogenase activity
LIS80_RS07480	COG0733	neurotransmitter:sodium symporter activity
LIS80_RS07505	COG1757	Na H antiporter
LIS80_RS07520	COG4758	membrane
LIS80_RS07525	COG4585	Histidine kinase
LIS80_RS07530	COG2197	response regulator
LIS80_RS07540	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS07550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIS80_RS07590	COG0730	response to heat
LIS80_RS07595	COG0306	phosphate transporter
LIS80_RS07600	COG1392	Phosphate transport regulator
LIS80_RS07605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_RS07620	COG3852	Histidine kinase
LIS80_RS07625	COG1801	Protein of unknown function DUF72
LIS80_RS07635	COG0582	viral genome integration into host DNA
LIS80_RS07640	COG5002	protein histidine kinase activity
LIS80_RS07655	COG0392	lysyltransferase activity
LIS80_RS07655	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LIS80_RS07670	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_RS07675	COG1686	Belongs to the peptidase S11 family
LIS80_RS07680	COG2715	membrane protein required for spore maturation
LIS80_RS07685	COG0700	Nucleoside recognition
LIS80_RS07690	COG1187	pseudouridine synthase activity
LIS80_RS07700	COG1333	cytochrome c biogenesis protein
LIS80_RS07705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIS80_RS07710	COG0745	RESPONSE REGULATOR receiver
LIS80_RS07715	COG5002	protein histidine kinase activity
LIS80_RS07720	COG2096	Adenosyltransferase
LIS80_RS07725	COG4942	peptidase
LIS80_RS07735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LIS80_RS07740	COG1141	Ferredoxin
LIS80_RS07750	COG0514	ATP-dependent DNA helicase (RecQ)
LIS80_RS07755	COG1266	CAAX protease self-immunity
LIS80_RS07765	COG1408	metallophosphoesterase
LIS80_RS07775	COG4862	establishment of competence for transformation
LIS80_RS07780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LIS80_RS07800	COG0492	ferredoxin-NADP+ reductase activity
LIS80_RS07805	COG0252	asparaginase activity
LIS80_RS07880	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_RS07895	COG0142	geranyltranstransferase activity
LIS80_RS07905	COG0142	geranyltranstransferase activity
LIS80_RS07925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LIS80_RS07935	COG0457	Tetratricopeptide repeat
LIS80_RS07955	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LIS80_RS07960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LIS80_RS07960	COG2010	Cytochrome c
LIS80_RS07965	COG4347	Protein of unknown function (DUF1405)
LIS80_RS07980	COG2738	Putative neutral zinc metallopeptidase
LIS80_RS07990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS07995	COG1694	Mazg nucleotide pyrophosphohydrolase
LIS80_RS08010	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LIS80_RS08015	COG0438	transferase activity, transferring glycosyl groups
LIS80_RS08050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LIS80_RS08050	COG1199	ATP-dependent helicase activity
LIS80_RS08070	COG3935	DnaD domain protein
LIS80_RS08075	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LIS80_RS08085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_RS08085	COG4499	WXG100 protein secretion system (Wss), protein YukC
LIS80_RS08145	COG0116	Belongs to the methyltransferase superfamily
LIS80_RS08155	COG1199	ATP-dependent helicase activity
LIS80_RS08160	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LIS80_RS08170	COG0024	Methionine aminopeptidase
LIS80_RS08180	COG2233	PERMEase
LIS80_RS08185	COG2311	Membrane
LIS80_RS08190	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_RS08200	COG0456	acetyltransferase
LIS80_RS08235	COG0754	glutathionylspermidine amidase activity
LIS80_RS08250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_RS08270	COG0454	-acetyltransferase
LIS80_RS08290	COG0328	RNA-DNA hybrid ribonuclease activity
LIS80_RS08325	COG3403	YqcI/YcgG family
LIS80_RS08330	COG1280	lysine exporter protein (LysE YggA)
LIS80_RS08345	COG3162	membrane
LIS80_RS08350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_RS08355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_RS08365	COG0475	glutathione-regulated potassium exporter activity
LIS80_RS08370	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_RS08375	COG0789	Transcriptional regulator
LIS80_RS08375	COG4978	Transcriptional regulator
LIS80_RS08385	COG2323	membrane
LIS80_RS08390	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LIS80_RS08425	COG2814	Major facilitator Superfamily
LIS80_RS08455	COG1923	regulation of RNA biosynthetic process
LIS80_RS08465	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LIS80_RS08470	COG1360	Flagellar Motor Protein
LIS80_RS08475	COG2201	protein-glutamate methylesterase activity
LIS80_RS08480	COG2198	Histidine kinase
LIS80_RS08480	COG0643	Histidine kinase
LIS80_RS08485	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_RS08485	COG1776	CheC inhibitor of MCP methylation
LIS80_RS08500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LIS80_RS08520	COG1256	bacterial-type flagellum assembly
LIS80_RS08525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LIS80_RS08545	COG1815	bacterial-type flagellum-dependent cell motility
LIS80_RS08550	COG1558	bacterial-type flagellum-dependent cell motility
LIS80_RS08560	COG1766	The M ring may be actively involved in energy transduction
LIS80_RS08565	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_RS08575	COG1157	protein secretion by the type III secretion system
LIS80_RS08595	COG1749	Flagellar hook protein flgE
LIS80_RS08610	COG0835	chemotaxis
LIS80_RS08610	COG0784	Response regulator, receiver
LIS80_RS08620	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LIS80_RS08630	COG0741	lytic transglycosylase activity
LIS80_RS08640	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_RS08645	COG1776	CheC inhibitor of MCP methylation
LIS80_RS08645	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LIS80_RS08655	COG1338	Plays a role in the flagellum-specific transport system
LIS80_RS08660	COG1987	bacterial-type flagellum assembly
LIS80_RS08670	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LIS80_RS08675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LIS80_RS08680	COG1419	protein localization to endoplasmic reticulum
LIS80_RS08685	COG4786	Flagellar basal body rod
LIS80_RS08710	COG1309	transcriptional regulator
LIS80_RS08730	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_RS08745	COG3764	Sortase (surface protein transpeptidase)
LIS80_RS08750	COG3764	Sortase (surface protein transpeptidase)
LIS80_RS08775	COG0583	DNA-binding transcription factor activity
LIS80_RS08780	COG3842	ATPase activity
LIS80_RS08785	COG0725	ABC transporter, periplasmic molybdate-binding protein
LIS80_RS08795	COG1234	tRNA 3'-trailer cleavage
LIS80_RS08825	COG1686	Belongs to the peptidase S11 family
LIS80_RS08835	COG0406	alpha-ribazole phosphatase activity
LIS80_RS08855	COG1846	Transcriptional regulator
LIS80_RS08865	COG0367	asparagine synthase
LIS80_RS08895	COG1802	Transcriptional regulator
LIS80_RS08900	COG0697	spore germination
LIS80_RS08905	COG0438	transferase activity, transferring glycosyl groups
LIS80_RS08905	COG1216	Glycosyl transferase, family 2
LIS80_RS08910	COG1757	Na H antiporter
LIS80_RS08920	COG0114	fumarate hydratase activity
LIS80_RS08945	COG0534	Mate efflux family protein
LIS80_RS08950	COG3340	Belongs to the peptidase S51 family
LIS80_RS08990	COG2733	membrane
LIS80_RS09025	COG1131	(ABC) transporter
LIS80_RS09040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS09045	COG4585	Histidine kinase
LIS80_RS09050	COG2197	response regulator
LIS80_RS09065	COG0528	UMP kinase activity
LIS80_RS09075	COG1027	Aspartate ammonia-lyase
LIS80_RS09080	COG0281	malic enzyme
LIS80_RS09085	COG4191	Histidine kinase
LIS80_RS09090	COG0784	Response regulator, receiver
LIS80_RS09095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_RS09115	COG3620	sequence-specific DNA binding
LIS80_RS09145	COG1051	belongs to the nudix hydrolase family
LIS80_RS09150	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS09160	COG2814	Major facilitator Superfamily
LIS80_RS09180	COG1966	Carbon starvation protein
LIS80_RS09190	COG1695	Transcriptional regulator
LIS80_RS09200	COG0477	Major facilitator Superfamily
LIS80_RS09205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_RS09215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LIS80_RS09220	COG4166	transmembrane transport
LIS80_RS09225	COG2223	nitrite transmembrane transporter activity
LIS80_RS09230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_RS09245	COG2244	polysaccharide biosynthetic process
LIS80_RS09250	COG0733	neurotransmitter:sodium symporter activity
LIS80_RS09260	COG5566	PFAM Mor transcription activator
LIS80_RS09265	COG2323	membrane
LIS80_RS09280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_RS09285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_RS09290	COG0028	Belongs to the TPP enzyme family
LIS80_RS09295	COG0440	acetolactate synthase activity
LIS80_RS09310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LIS80_RS09335	COG2814	Major facilitator Superfamily
LIS80_RS09340	COG3384	dioxygenase
LIS80_RS09350	COG3279	Response regulator of the LytR AlgR family
LIS80_RS09355	COG0427	acetyl-CoA hydrolase
LIS80_RS09375	COG1073	alpha beta
LIS80_RS09380	COG4166	transmembrane transport
LIS80_RS09385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS09390	COG0745	RESPONSE REGULATOR receiver
LIS80_RS09405	COG1914	H( )-stimulated, divalent metal cation uptake system
LIS80_RS09420	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIS80_RS09425	COG0531	amino acid
LIS80_RS09445	COG0457	Tetratricopeptide repeat
LIS80_RS09455	COG2390	Transcriptional regulator
LIS80_RS09465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS09470	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LIS80_RS09480	COG4846	Membrane protein involved in cytochrome C biogenesis
LIS80_RS09490	COG0006	proline dipeptidase activity
LIS80_RS09505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIS80_RS09530	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS09540	COG2372	response to copper ion
LIS80_RS09540	COG1276	copper resistance
LIS80_RS09550	COG0697	spore germination
LIS80_RS09555	COG0583	DNA-binding transcription factor activity
LIS80_RS09560	COG1959	2 iron, 2 sulfur cluster binding
LIS80_RS09565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LIS80_RS09570	COG0778	Nitroreductase
LIS80_RS09580	COG0628	permease
LIS80_RS09590	COG1231	oxidoreductase activity
LIS80_RS09595	COG0523	cobalamin synthesis protein
LIS80_RS09605	COG0411	ABC transporter
LIS80_RS09635	COG1942	4-Oxalocrotonate Tautomerase
LIS80_RS09655	COG1271	oxidase subunit
LIS80_RS09660	COG1294	oxidase, subunit
LIS80_RS09665	COG4988	ABC transporter
LIS80_RS09670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LIS80_RS09680	COG1216	Glycosyl transferase, family 2
LIS80_RS09720	COG1686	Belongs to the peptidase S11 family
LIS80_RS09735	COG0791	NLP P60 protein
LIS80_RS09735	COG1388	LysM domain
LIS80_RS09745	COG1132	(ABC) transporter
LIS80_RS09750	COG0745	RESPONSE REGULATOR receiver
LIS80_RS09755	COG5002	protein histidine kinase activity
LIS80_RS09765	COG0300	oxidoreductase activity
LIS80_RS09770	COG4122	O-methyltransferase activity
LIS80_RS09800	COG0460	homoserine dehydrogenase
LIS80_RS09825	COG1316	TRANSCRIPTIONal
LIS80_RS09845	COG1285	pathogenesis
LIS80_RS09850	COG1247	-acetyltransferase
LIS80_RS09860	COG2814	Major facilitator Superfamily
LIS80_RS09865	COG1279	arginine transmembrane transporter activity
LIS80_RS09870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS09880	COG1752	Esterase of the alpha-beta hydrolase superfamily
LIS80_RS09915	COG0577	efflux transmembrane transporter activity
LIS80_RS09920	COG2002	toxin-antitoxin pair type II binding
LIS80_RS09925	COG1404	Belongs to the peptidase S8 family
LIS80_RS09930	COG3842	ATPase activity
LIS80_RS09935	COG2508	Transcriptional regulator
LIS80_RS09945	COG1653	transport
LIS80_RS09950	COG1175	transmembrane transport
LIS80_RS09955	COG0395	ABC-type sugar transport system, permease component
LIS80_RS09960	COG5426	von Willebrand factor, type A
LIS80_RS09970	COG1940	carbohydrate kinase activity
LIS80_RS09975	COG2222	sugar isomerase
LIS80_RS09985	COG1105	Belongs to the carbohydrate kinase PfkB family
LIS80_RS09990	COG3684	Belongs to the aldolase LacD family
LIS80_RS09995	COG0366	Alpha amylase catalytic
LIS80_RS10000	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LIS80_RS10005	COG0640	Transcriptional regulator
LIS80_RS10010	COG0667	Aldo Keto reductase
LIS80_RS10015	COG2814	Major facilitator Superfamily
LIS80_RS10040	COG0840	transmembrane signaling receptor activity
LIS80_RS10055	COG3949	Membrane
LIS80_RS10060	COG0783	Belongs to the Dps family
LIS80_RS10075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_RS10085	COG1231	oxidoreductase activity
LIS80_RS10090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS10095	COG4989	oxidoreductase activity
LIS80_RS10100	COG0523	cobalamin synthesis protein
LIS80_RS10105	COG0456	acetyltransferase
LIS80_RS10110	COG0803	Belongs to the bacterial solute-binding protein 9 family
LIS80_RS10110	COG3443	Belongs to the bacterial solute-binding protein 9 family
LIS80_RS10120	COG0702	epimerase
LIS80_RS10130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIS80_RS10140	COG4166	transmembrane transport
LIS80_RS10155	COG0406	alpha-ribazole phosphatase activity
LIS80_RS10165	COG5337	Spore coat protein CotH
LIS80_RS10170	COG1051	belongs to the nudix hydrolase family
LIS80_RS10175	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS10180	COG2244	polysaccharide biosynthetic process
LIS80_RS10190	COG0701	Predicted permease
LIS80_RS10195	COG3689	TIGRFAM TIGR03943 family protein
LIS80_RS10200	COG1607	acyl-coa hydrolase
LIS80_RS10210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS10225	COG0702	epimerase
LIS80_RS10230	COG2839	Protein conserved in bacteria
LIS80_RS10235	COG1253	flavin adenine dinucleotide binding
LIS80_RS10255	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS10260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_RS10280	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS10290	COG1876	peptidase activity
LIS80_RS10300	COG0154	amidase activity
LIS80_RS10305	COG2211	Major facilitator Superfamily
LIS80_RS10325	COG0561	phosphatase activity
LIS80_RS10335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LIS80_RS10340	COG4106	trans-aconitate 2-methyltransferase activity
LIS80_RS10355	COG1819	glycosyl
LIS80_RS10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS10365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS10395	COG0456	acetyltransferase
LIS80_RS10420	COG3874	Sporulation protein YtfJ
LIS80_RS10445	COG2226	methyltransferase
LIS80_RS10470	COG0582	viral genome integration into host DNA
LIS80_RS10480	COG3620	sequence-specific DNA binding
LIS80_RS10535	COG1191	sigma factor activity
LIS80_RS10560	COG0756	dUTP diphosphatase activity
LIS80_RS10605	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LIS80_RS10610	COG0582	viral genome integration into host DNA
LIS80_RS10645	COG4626	Terminase
LIS80_RS10645	COG1802	Transcriptional regulator
LIS80_RS10655	COG0740	serine-type endopeptidase activity
LIS80_RS10735	COG4824	toxin secretion phage lysis holin
LIS80_RS10790	COG0604	alcohol dehydrogenase
LIS80_RS10795	COG1595	DNA-templated transcription, initiation
LIS80_RS10810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LIS80_RS10810	COG0426	domain, Protein
LIS80_RS10820	COG0386	Belongs to the glutathione peroxidase family
LIS80_RS10825	COG1305	Transglutaminase-like
LIS80_RS10830	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LIS80_RS10835	COG0714	Associated with various cellular activities
LIS80_RS10850	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LIS80_RS10855	COG1140	nitrate reductase beta subunit
LIS80_RS10860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
LIS80_RS10865	COG2181	nitrate reductase activity
LIS80_RS10870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIS80_RS10875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LIS80_RS10880	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_RS10885	COG0303	'Molybdopterin
LIS80_RS10890	COG0314	molybdopterin synthase activity
LIS80_RS10900	COG2223	nitrite transmembrane transporter activity
LIS80_RS10920	COG1648	precorrin-2 dehydrogenase activity
LIS80_RS10930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LIS80_RS10930	COG1587	Uroporphyrinogen-III synthase
LIS80_RS10935	COG2146	nitrite reductase [NAD(P)H] activity
LIS80_RS10940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LIS80_RS10945	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
LIS80_RS10980	COG2359	stage V sporulation protein S
LIS80_RS11000	COG1418	mRNA catabolic process
LIS80_RS11005	COG0488	(ABC) transporter
LIS80_RS11020	COG0629	single-stranded DNA binding
LIS80_RS11035	COG1413	lyase activity
LIS80_RS11050	COG2136	Putative SAM-dependent methyltransferase
LIS80_RS11050	COG2521	methyltransferase
LIS80_RS11085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LIS80_RS11090	COG0017	Asparaginyl-tRNA synthetase
LIS80_RS11095	COG0733	neurotransmitter:sodium symporter activity
LIS80_RS11120	COG2610	gluconate transmembrane transporter activity
LIS80_RS11125	COG1454	alcohol dehydrogenase
LIS80_RS11130	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_RS11140	COG0456	acetyltransferase
LIS80_RS11145	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LIS80_RS11155	COG1131	(ABC) transporter
LIS80_RS11160	COG4473	ABC transporter
LIS80_RS11170	COG0546	phosphoglycolate phosphatase activity
LIS80_RS11185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_RS11190	COG3250	beta-galactosidase activity
LIS80_RS11205	COG0768	penicillin binding
LIS80_RS11215	COG0204	Acyl-transferase
LIS80_RS11220	COG1272	protein, Hemolysin III
LIS80_RS11230	COG0805	protein transport
LIS80_RS11240	COG1307	EDD domain protein, DegV family
LIS80_RS11245	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LIS80_RS11250	COG1999	signal sequence binding
LIS80_RS11255	COG0071	Belongs to the small heat shock protein (HSP20) family
LIS80_RS11260	COG0367	asparagine synthase
LIS80_RS11275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS11280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LIS80_RS11295	COG1335	isochorismatase
LIS80_RS11300	COG1051	belongs to the nudix hydrolase family
LIS80_RS11310	COG0668	transmembrane transport
LIS80_RS11315	COG2203	Gaf domain
LIS80_RS11315	COG4585	Histidine kinase
LIS80_RS11320	COG2197	response regulator
LIS80_RS11330	COG1064	alcohol dehydrogenase
LIS80_RS11390	COG0517	IMP dehydrogenase activity
LIS80_RS11390	COG1125	glycine betaine transport
LIS80_RS11395	COG1174	glycine betaine transport
LIS80_RS11430	COG1253	flavin adenine dinucleotide binding
LIS80_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS11440	COG5506	Protein of unknown function (DUF1694)
LIS80_RS11455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_RS11460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LIS80_RS11465	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LIS80_RS11470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_RS11475	COG0456	acetyltransferase
LIS80_RS11480	COG3829	transcription factor binding
LIS80_RS11485	COG1509	lysine 2,3-aminomutase activity
LIS80_RS11520	COG0515	serine threonine protein kinase
LIS80_RS11520	COG4991	sh3 domain protein
LIS80_RS11520	COG3064	Membrane
LIS80_RS11525	COG4326	sporulation control protein
LIS80_RS11530	COG0671	phosphoesterase, PA-phosphatase related
LIS80_RS11535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LIS80_RS11540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS11555	COG3728	DNA packaging
LIS80_RS11555	COG5484	DNA packaging
LIS80_RS11590	COG1595	DNA-templated transcription, initiation
LIS80_RS11620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LIS80_RS11675	COG4499	WXG100 protein secretion system (Wss), protein YukC
LIS80_RS11675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_RS11685	COG2814	Major facilitator Superfamily
LIS80_RS11695	COG0372	Belongs to the citrate synthase family
LIS80_RS11700	COG2079	MmgE PrpD family protein
LIS80_RS11705	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LIS80_RS11710	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS11715	COG2084	Dehydrogenase
LIS80_RS11725	COG1280	lysine exporter protein (LysE YggA)
LIS80_RS11730	COG1024	Enoyl-CoA hydratase
LIS80_RS11745	COG0420	3'-5' exonuclease activity
LIS80_RS11775	COG2223	nitrite transmembrane transporter activity
LIS80_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS11785	COG1169	isochorismate synthase
LIS80_RS11790	COG1021	2,3-dihydroxybenzoate-AMP ligase
LIS80_RS11795	COG1535	isochorismatase
LIS80_RS11795	COG3433	isochorismatase activity
LIS80_RS11800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LIS80_RS11805	COG3251	PFAM MbtH domain protein
LIS80_RS11810	COG2814	Major facilitator Superfamily
LIS80_RS11825	COG0776	regulation of translation
LIS80_RS11835	COG2318	DinB family
LIS80_RS11845	COG1115	amino acid carrier protein
LIS80_RS11870	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_RS11875	COG1187	pseudouridine synthase activity
LIS80_RS11880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LIS80_RS11885	COG1136	(ABC) transporter
LIS80_RS11920	COG0028	Belongs to the TPP enzyme family
LIS80_RS11990	COG1247	-acetyltransferase
LIS80_RS12015	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LIS80_RS12020	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LIS80_RS12030	COG2226	methyltransferase
LIS80_RS12035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS12045	COG1278	Cold shock
LIS80_RS12060	COG0010	Belongs to the arginase family
LIS80_RS12065	COG0561	phosphatase activity
LIS80_RS12075	COG1846	Transcriptional regulator
LIS80_RS12080	COG2814	Major facilitator Superfamily
LIS80_RS12085	COG0583	DNA-binding transcription factor activity
LIS80_RS12090	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIS80_RS12105	COG0583	DNA-binding transcription factor activity
LIS80_RS12110	COG2258	MOSC domain
LIS80_RS12125	COG1132	(ABC) transporter
LIS80_RS12130	COG1132	(ABC) transporter
LIS80_RS12145	COG1396	sequence-specific DNA binding
LIS80_RS12185	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LIS80_RS12190	COG1595	DNA-templated transcription, initiation
LIS80_RS12220	COG1649	PFAM Uncharacterised BCR, COG1649
LIS80_RS12245	COG2971	BadF BadG BcrA BcrD
LIS80_RS12255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LIS80_RS12310	COG1309	transcriptional regulator
LIS80_RS12325	COG1136	(ABC) transporter
LIS80_RS12325	COG0577	efflux transmembrane transporter activity
LIS80_RS12330	COG0500	methyltransferase
LIS80_RS12330	COG3615	Tellurite resistance protein tehB
LIS80_RS12345	COG3961	Belongs to the TPP enzyme family
LIS80_RS12375	COG2195	Cleaves the N-terminal amino acid of tripeptides
LIS80_RS12390	COG1595	DNA-templated transcription, initiation
LIS80_RS12400	COG0768	penicillin binding
LIS80_RS12405	COG0768	penicillin binding
LIS80_RS12410	COG2367	Beta-lactamase
LIS80_RS12415	COG1408	metallophosphoesterase
LIS80_RS12425	COG1131	(ABC) transporter
LIS80_RS12435	COG1309	transcriptional regulator
LIS80_RS12450	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS12455	COG0439	Biotin carboxylase
LIS80_RS12460	COG0511	ligase activity, forming carbon-carbon bonds
LIS80_RS12465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LIS80_RS12470	COG1024	Enoyl-CoA hydratase
LIS80_RS12475	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LIS80_RS12480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_RS12495	COG0572	uridine kinase
LIS80_RS12505	COG2318	DinB family
LIS80_RS12510	COG1686	Belongs to the peptidase S11 family
LIS80_RS12535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LIS80_RS12560	COG3227	Zinc metalloprotease (Elastase)
LIS80_RS12610	COG2226	methyltransferase
LIS80_RS12640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS12655	COG1063	alcohol dehydrogenase
LIS80_RS12665	COG2323	membrane
LIS80_RS12670	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LIS80_RS12680	COG3386	PFAM SMP-30 Gluconolaconase
LIS80_RS12690	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LIS80_RS12695	COG3773	Cell wall hydrolase
LIS80_RS12705	COG0745	RESPONSE REGULATOR receiver
LIS80_RS12710	COG2205	protein histidine kinase activity
LIS80_RS12720	COG0488	(ABC) transporter
LIS80_RS12725	COG1136	(ABC) transporter
LIS80_RS12730	COG0577	efflux transmembrane transporter activity
LIS80_RS12750	COG0460	homoserine dehydrogenase
LIS80_RS12755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS12765	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LIS80_RS12815	COG2124	cytochrome p450
LIS80_RS12845	COG0561	phosphatase activity
LIS80_RS12875	COG5002	protein histidine kinase activity
LIS80_RS12880	COG0768	penicillin binding
LIS80_RS12890	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_RS12915	COG2205	protein histidine kinase activity
LIS80_RS12925	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_RS12930	COG0604	alcohol dehydrogenase
LIS80_RS12935	COG0671	phosphoesterase, PA-phosphatase related
LIS80_RS12940	COG0768	penicillin binding
LIS80_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS13005	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_RS13020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS13025	COG0697	spore germination
LIS80_RS13035	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIS80_RS13050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_RS13060	COG2223	nitrite transmembrane transporter activity
LIS80_RS13075	COG2816	NAD+ diphosphatase activity
LIS80_RS13080	COG0592	DNA-directed DNA polymerase activity
LIS80_RS13085	COG1051	belongs to the nudix hydrolase family
LIS80_RS13115	COG3878	Protein conserved in bacteria
LIS80_RS13140	COG4667	esterase of the alpha-beta hydrolase superfamily
LIS80_RS13180	COG0322	excinuclease ABC activity
LIS80_RS13220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_RS13245	COG1011	Hydrolase
LIS80_RS13265	COG1523	belongs to the glycosyl hydrolase 13 family
LIS80_RS13270	COG3227	Zinc metalloprotease (Elastase)
LIS80_RS13290	COG0201	protein transport
LIS80_RS13335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS13350	COG2959	enzyme of heme biosynthesis
LIS80_RS13385	COG1309	transcriptional regulator
LIS80_RS13415	COG3284	Transcriptional regulator
LIS80_RS13435	COG1349	DNA-binding transcription factor activity
LIS80_RS13450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIS80_RS13455	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_RS13460	COG0022	dehydrogenase e1 component
LIS80_RS13465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS13480	COG0456	acetyltransferase
LIS80_RS13480	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_RS13495	COG0494	nUDIX hydrolase
LIS80_RS13520	COG4176	ABC-type proline glycine betaine transport system permease component
LIS80_RS13525	COG0517	IMP dehydrogenase activity
LIS80_RS13525	COG4175	Glycine betaine
LIS80_RS13555	COG2153	protein acetylation
LIS80_RS13560	COG1819	glycosyl
LIS80_RS13580	COG2205	protein histidine kinase activity
LIS80_RS13585	COG2226	methyltransferase
LIS80_RS13590	COG2315	Protein conserved in bacteria
LIS80_RS13605	COG3344	reverse transcriptase
LIS80_RS13650	COG3973	AAA domain
LIS80_RS13670	COG0514	ATP-dependent DNA helicase (RecQ)
LIS80_RS13700	COG4637	Psort location Cytoplasmic, score
LIS80_RS13720	COG3397	chitin binding
LIS80_RS13735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LIS80_RS13740	COG1115	amino acid carrier protein
LIS80_RS13745	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LIS80_RS13760	COG3938	Belongs to the proline racemase family
LIS80_RS13765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_RS13805	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS13810	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LIS80_RS13815	COG0519	Catalyzes the synthesis of GMP from XMP
LIS80_RS13820	COG4166	transmembrane transport
LIS80_RS13830	COG4948	Mandelate Racemase Muconate Lactonizing
LIS80_RS13880	COG2936	dipeptidyl-peptidase activity
LIS80_RS13890	COG0745	RESPONSE REGULATOR receiver
LIS80_RS13925	COG1164	Oligoendopeptidase f
LIS80_RS13935	COG1307	EDD domain protein, DegV family
LIS80_RS13975	COG2814	Major facilitator Superfamily
LIS80_RS13985	COG1664	Polymer-forming cytoskeletal
LIS80_RS13990	COG0789	Transcriptional regulator
LIS80_RS13995	COG4533	DNA binding
LIS80_RS14000	COG0477	Major facilitator Superfamily
LIS80_RS14000	COG2814	Major facilitator Superfamily
LIS80_RS14025	COG2261	transglycosylase associated protein
LIS80_RS14040	COG2226	methyltransferase
LIS80_RS14070	COG0436	Aminotransferase
LIS80_RS14075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LIS80_RS14080	COG5146	pantothenate kinase activity
LIS80_RS14085	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LIS80_RS14140	COG0628	permease
LIS80_RS14155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_RS14160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_RS14165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_RS14210	COG2746	aminoglycoside 3-N-acetyltransferase activity
LIS80_RS14230	COG0697	spore germination
LIS80_RS14235	COG2318	DinB family
LIS80_RS14280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS14285	COG0861	Integral membrane protein TerC family
LIS80_RS14290	COG1368	sulfuric ester hydrolase activity
LIS80_RS14295	COG0488	(ABC) transporter
LIS80_RS14305	COG1033	growth of symbiont in host cell
LIS80_RS14305	COG2409	Drug exporters of the RND superfamily
LIS80_RS14310	COG1309	transcriptional regulator
LIS80_RS14325	COG0287	Prephenate dehydrogenase
LIS80_RS14340	COG1605	Chorismate mutase
LIS80_RS14340	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LIS80_RS14370	COG1388	LysM domain
LIS80_RS14370	COG3584	3D domain protein
LIS80_RS14395	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS14405	COG2390	Transcriptional regulator
LIS80_RS14410	COG1070	Carbohydrate kinase
LIS80_RS14430	COG2329	Antibiotic biosynthesis monooxygenase
LIS80_RS14445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS14460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_RS14465	COG4187	Peptidase family M20/M25/M40
LIS80_RS14470	COG1414	Transcriptional regulator
LIS80_RS14475	COG0833	amino acid
LIS80_RS14480	COG1690	Belongs to the RtcB family
LIS80_RS14485	COG3239	Fatty acid desaturase
LIS80_RS14495	COG1785	Belongs to the alkaline phosphatase family
LIS80_RS14505	COG3655	Transcriptional regulator
LIS80_RS14520	COG4377	Putative membrane peptidase family (DUF2324)
LIS80_RS14530	COG3279	Response regulator of the LytR AlgR family
LIS80_RS14545	COG0346	lactoylglutathione lyase activity
LIS80_RS14565	COG0714	Associated with various cellular activities
LIS80_RS14585	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LIS80_RS14590	COG0753	catalase activity
LIS80_RS14595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_RS14615	COG1846	Transcriptional regulator
LIS80_RS14620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LIS80_RS14645	COG0714	Associated with various cellular activities
LIS80_RS14655	COG0778	Nitroreductase
LIS80_RS14660	COG1846	Transcriptional regulator
LIS80_RS14695	COG1725	Transcriptional regulator
LIS80_RS14705	COG1136	(ABC) transporter
LIS80_RS14730	COG1136	(ABC) transporter
LIS80_RS14760	COG0456	acetyltransferase
LIS80_RS14780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS14795	COG0642	Histidine kinase
LIS80_RS14800	COG0745	RESPONSE REGULATOR receiver
LIS80_RS14805	COG0596	Alpha beta hydrolase
LIS80_RS14835	COG0730	response to heat
LIS80_RS14845	COG0833	amino acid
LIS80_RS14855	COG4335	DNA alkylation repair
LIS80_RS14860	COG4978	Transcriptional regulator
LIS80_RS14860	COG0789	Transcriptional regulator
LIS80_RS14895	COG0768	penicillin binding
LIS80_RS14930	COG1984	allophanate hydrolase subunit 2
LIS80_RS14935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LIS80_RS14940	COG1414	Transcriptional regulator
LIS80_RS14950	COG3142	Participates in the control of copper homeostasis
LIS80_RS14955	COG0860	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS14960	COG0640	Transcriptional regulator
LIS80_RS14970	COG2814	Major facilitator Superfamily
LIS80_RS14980	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS14995	COG3314	Sporulation integral membrane protein YlbJ
LIS80_RS15020	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LIS80_RS15035	COG0574	Belongs to the PEP-utilizing enzyme family
LIS80_RS15035	COG3848	Pyruvate phosphate dikinase
LIS80_RS15045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS15060	COG5577	PFAM Coat F domain
LIS80_RS15065	COG3403	YqcI/YcgG family
LIS80_RS15070	COG1280	lysine exporter protein (LysE YggA)
LIS80_RS15075	COG1113	amino acid transport
LIS80_RS15105	COG1063	alcohol dehydrogenase
LIS80_RS15115	COG1027	Aspartate ammonia-lyase
LIS80_RS15120	COG0252	asparaginase activity
LIS80_RS15125	COG1396	sequence-specific DNA binding
LIS80_RS15130	COG0322	excinuclease ABC activity
LIS80_RS15135	COG0531	amino acid
LIS80_RS15140	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_RS15150	COG0531	amino acid
LIS80_RS15160	COG0784	Response regulator, receiver
LIS80_RS15165	COG4191	Histidine kinase
LIS80_RS15170	COG2066	Belongs to the glutaminase family
LIS80_RS15175	COG1115	amino acid carrier protein
LIS80_RS15195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LIS80_RS15195	COG0723	plastoquinol--plastocyanin reductase activity
LIS80_RS15200	COG0534	Mate efflux family protein
LIS80_RS15210	COG0531	amino acid
LIS80_RS15215	COG0737	Belongs to the 5'-nucleotidase family
LIS80_RS15220	COG0753	catalase activity
LIS80_RS15230	COG0598	Magnesium transport protein CorA
LIS80_RS15280	COG0415	Belongs to the DNA photolyase family
LIS80_RS15295	COG0288	reversible hydration of carbon dioxide
LIS80_RS15305	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LIS80_RS15310	COG5609	conserved protein (DUF2294)
LIS80_RS15325	COG0697	spore germination
LIS80_RS15335	COG1575	Belongs to the MenA family. Type 1 subfamily
LIS80_RS15340	COG4641	Protein conserved in bacteria
LIS80_RS15345	COG1136	(ABC) transporter
LIS80_RS15350	COG0577	efflux transmembrane transporter activity
LIS80_RS15385	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS15385	COG3347	Dehydrogenase
LIS80_RS15395	COG1070	Carbohydrate kinase
LIS80_RS15400	COG0235	Class ii aldolase
LIS80_RS15410	COG1172	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS15420	COG4154	Belongs to the RbsD FucU family
LIS80_RS15445	COG0798	PFAM Bile acid sodium symporter
LIS80_RS15450	COG0346	lactoylglutathione lyase activity
LIS80_RS15455	COG0640	Transcriptional regulator
LIS80_RS15465	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LIS80_RS15485	COG1136	(ABC) transporter
LIS80_RS15525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIS80_RS15525	COG3320	Male sterility
LIS80_RS15530	COG1309	transcriptional regulator
LIS80_RS15535	COG2814	Major facilitator Superfamily
LIS80_RS15540	COG1309	transcriptional regulator
LIS80_RS15545	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS15550	COG1522	sequence-specific DNA binding
LIS80_RS15565	COG0346	lactoylglutathione lyase activity
LIS80_RS15600	COG2814	Major facilitator Superfamily
LIS80_RS15610	COG4895	conserved protein (DUF2196)
LIS80_RS15660	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LIS80_RS15680	COG0789	Transcriptional regulator
LIS80_RS15685	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LIS80_RS15705	COG0577	efflux transmembrane transporter activity
LIS80_RS15725	COG3850	Histidine kinase
LIS80_RS15725	COG5002	protein histidine kinase activity
LIS80_RS15735	COG2364	Membrane
LIS80_RS15740	COG1846	Transcriptional regulator
LIS80_RS15745	COG0456	acetyltransferase
LIS80_RS15750	COG2808	Putative FMN-binding domain
LIS80_RS15755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS15760	COG2271	Major facilitator Superfamily
LIS80_RS15765	COG1556	Lactate utilization protein
LIS80_RS15770	COG1139	Iron-sulfur cluster binding protein
LIS80_RS15780	COG0583	DNA-binding transcription factor activity
LIS80_RS15795	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_RS15810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LIS80_RS15830	COG0662	Cupin 2, conserved barrel domain protein
LIS80_RS15835	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS15835	COG2207	Transcriptional regulator
LIS80_RS15855	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_RS15855	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS15895	COG0477	Major facilitator Superfamily
LIS80_RS15910	COG1846	Transcriptional regulator
LIS80_RS15915	COG2814	Major facilitator Superfamily
LIS80_RS15925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_RS15930	COG1131	(ABC) transporter
LIS80_RS15950	COG2076	Multidrug Resistance protein
LIS80_RS15955	COG1309	transcriptional regulator
LIS80_RS15965	COG2031	fatty acid transporter
LIS80_RS15975	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS16010	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LIS80_RS16025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LIS80_RS16030	COG1288	antiporter activity
LIS80_RS16055	COG0789	Transcriptional regulator
LIS80_RS16070	COG3620	sequence-specific DNA binding
LIS80_RS16075	COG0494	nUDIX hydrolase
LIS80_RS16090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LIS80_RS16115	COG1733	regulation of RNA biosynthetic process
LIS80_RS16120	COG0778	Nitroreductase
LIS80_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS16150	COG1131	(ABC) transporter
LIS80_RS16175	COG1011	Hydrolase
LIS80_RS16180	COG2365	Tyrosine phosphatase family
LIS80_RS16200	COG0346	lactoylglutathione lyase activity
LIS80_RS16205	COG1940	carbohydrate kinase activity
LIS80_RS16210	COG0110	maltose O-acetyltransferase activity
LIS80_RS16225	COG0628	permease
LIS80_RS16255	COG0500	methyltransferase
LIS80_RS16265	COG0477	Major facilitator Superfamily
LIS80_RS16290	COG1253	flavin adenine dinucleotide binding
LIS80_RS16295	COG0789	Transcriptional regulator
LIS80_RS16305	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIS80_RS16335	COG0697	spore germination
LIS80_RS16350	COG1357	PFAM Pentapeptide repeats (8 copies)
LIS80_RS16355	COG3813	Protein conserved in bacteria
LIS80_RS16360	COG2706	6-phosphogluconolactonase activity
LIS80_RS16365	COG1070	Carbohydrate kinase
LIS80_RS16375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LIS80_RS16380	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LIS80_RS16390	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LIS80_RS16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LIS80_RS16415	COG0604	alcohol dehydrogenase
LIS80_RS16415	COG3321	synthase
LIS80_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS16435	COG0656	L-ascorbic acid biosynthetic process
LIS80_RS16440	COG2814	Major facilitator Superfamily
LIS80_RS16455	COG0346	lactoylglutathione lyase activity
LIS80_RS16460	COG0814	amino acid
LIS80_RS16485	COG1393	Belongs to the ArsC family
LIS80_RS16490	COG1733	regulation of RNA biosynthetic process
LIS80_RS16495	COG2188	Transcriptional regulator
LIS80_RS16500	COG0673	inositol 2-dehydrogenase activity
LIS80_RS16505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LIS80_RS16510	COG1733	regulation of RNA biosynthetic process
LIS80_RS16515	COG1733	regulation of RNA biosynthetic process
LIS80_RS16535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS16555	COG0384	phenazine biosynthesis protein PhzF
LIS80_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS16580	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_RS16585	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS16590	COG1733	regulation of RNA biosynthetic process
LIS80_RS16615	COG1191	sigma factor activity
LIS80_RS16635	COG1309	transcriptional regulator
LIS80_RS16680	COG1151	hydroxylamine reductase activity
LIS80_RS16690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS16725	COG2072	flavoprotein involved in K transport
LIS80_RS16760	COG0604	alcohol dehydrogenase
LIS80_RS16765	COG1113	amino acid transport
LIS80_RS16795	COG2814	Major facilitator Superfamily
LIS80_RS16820	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LIS80_RS16825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_RS16840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS16845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS16850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS16855	COG3739	integral membrane protein
LIS80_RS16875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS16890	COG0583	DNA-binding transcription factor activity
LIS80_RS16900	COG2890	protein-(glutamine-N5) methyltransferase activity
LIS80_RS16915	COG1193	negative regulation of DNA recombination
LIS80_RS16920	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LIS80_RS16925	COG1164	Oligoendopeptidase f
LIS80_RS16930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LIS80_RS16970	COG0640	Transcriptional regulator
LIS80_RS16975	COG0604	alcohol dehydrogenase
LIS80_RS17000	COG2808	Putative FMN-binding domain
LIS80_RS17005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_RS17015	COG0385	Bile acid
LIS80_RS17020	COG0277	FAD linked oxidase domain protein
LIS80_RS17050	COG1285	pathogenesis
LIS80_RS17065	COG2514	catechol 2,3-dioxygenase activity
LIS80_RS17070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS17075	COG1126	abc transporter atp-binding protein
LIS80_RS17080	COG0765	amino acid transport
LIS80_RS17085	COG2720	vancomycin resistance protein
LIS80_RS17125	COG0716	FMN binding
LIS80_RS17170	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS17180	COG0165	Argininosuccinate lyase
LIS80_RS17195	COG4145	pantothenate transmembrane transporter activity
LIS80_RS17245	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS17260	COG1657	PFAM Prenyltransferase squalene oxidase
LIS80_RS17265	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LIS80_RS17270	COG2962	Rard protein
LIS80_RS17275	COG3326	Membrane
LIS80_RS17290	COG0489	protein tyrosine kinase activity
LIS80_RS17300	COG0314	molybdopterin synthase activity
LIS80_RS17305	COG0303	'Molybdopterin
LIS80_RS17310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_RS17315	COG2116	formate transmembrane transporter activity
LIS80_RS17325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LIS80_RS17330	COG5609	conserved protein (DUF2294)
LIS80_RS17335	COG2427	Protein of unknown function (DUF1641)
LIS80_RS17340	COG3383	formate dehydrogenase (NAD+) activity
LIS80_RS17345	COG0697	spore germination
LIS80_RS17390	COG2226	methyltransferase
LIS80_RS17395	COG4166	transmembrane transport
LIS80_RS17400	COG4166	transmembrane transport
LIS80_RS17405	COG4166	transmembrane transport
LIS80_RS17410	COG1301	dicarboxylic acid transport
LIS80_RS17415	COG1316	TRANSCRIPTIONal
LIS80_RS17425	COG1595	DNA-templated transcription, initiation
LIS80_RS17430	COG0346	lactoylglutathione lyase activity
LIS80_RS17440	COG1131	(ABC) transporter
LIS80_RS17450	COG0673	inositol 2-dehydrogenase activity
LIS80_RS17455	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LIS80_RS17460	COG0187	DNA topoisomerase II activity
LIS80_RS17465	COG1832	CoA-binding protein
LIS80_RS17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_RS17475	COG0745	RESPONSE REGULATOR receiver
LIS80_RS17485	COG1328	CTP reductase activity
LIS80_RS17485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LIS80_RS17495	COG4841	protein insertion into membrane
LIS80_RS17500	COG0824	Thioesterase
LIS80_RS17530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS17540	COG1132	(ABC) transporter
LIS80_RS17545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LIS80_RS17575	COG2211	Major facilitator Superfamily
LIS80_RS17575	COG2211	Major facilitator Superfamily
LIS80_RS17580	COG4282	regulation of fungal-type cell wall biogenesis
LIS80_RS17600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LIS80_RS17625	COG0183	Belongs to the thiolase family
LIS80_RS17630	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_RS17635	COG1268	BioY protein
LIS80_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_RS17655	COG1396	sequence-specific DNA binding
LIS80_RS17700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS17710	COG5002	protein histidine kinase activity
LIS80_RS17715	COG0400	carboxylic ester hydrolase activity
LIS80_RS17720	COG0346	lactoylglutathione lyase activity
LIS80_RS17725	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LIS80_RS17735	COG0069	glutamate synthase activity
LIS80_RS17740	COG1902	pentaerythritol trinitrate reductase activity
LIS80_RS17745	COG1329	Transcriptional regulator
LIS80_RS17750	COG0010	Belongs to the arginase family
LIS80_RS17775	COG2226	methyltransferase
LIS80_RS17825	COG4846	Membrane protein involved in cytochrome C biogenesis
LIS80_RS17830	COG0785	Cytochrome C biogenesis protein
LIS80_RS17840	COG1473	amidohydrolase
LIS80_RS17850	COG1131	(ABC) transporter
LIS80_RS17860	COG0583	DNA-binding transcription factor activity
LIS80_RS17870	COG1346	cytolysis
LIS80_RS17885	COG0730	response to heat
LIS80_RS17895	COG5632	N-Acetylmuramoyl-L-alanine amidase
LIS80_RS17895	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_RS17915	COG1132	(ABC) transporter
LIS80_RS17920	COG1132	(ABC) transporter
LIS80_RS17945	COG3639	organic phosphonate transmembrane transporter activity
LIS80_RS17950	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LIS80_RS17955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS17960	COG0737	Belongs to the 5'-nucleotidase family
LIS80_RS17970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LIS80_RS17990	COG1695	Transcriptional regulator
LIS80_RS17995	COG0174	glutamine synthetase
LIS80_RS18000	COG0789	Transcriptional regulator
LIS80_RS18005	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LIS80_RS18010	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LIS80_RS18015	COG2860	membrane
LIS80_RS18020	COG0464	growth
LIS80_RS18050	COG3584	3D domain protein
LIS80_RS18050	COG1388	LysM domain
LIS80_RS18055	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS18055	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_RS18055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_RS18060	COG1105	Belongs to the carbohydrate kinase PfkB family
LIS80_RS18065	COG1349	DNA-binding transcription factor activity
LIS80_RS18070	COG1979	alcohol dehydrogenase
LIS80_RS18075	COG2322	membrane
LIS80_RS18085	COG1113	amino acid transport
LIS80_RS18095	COG1408	metallophosphoesterase
LIS80_RS18100	COG2116	formate transmembrane transporter activity
LIS80_RS18115	COG2217	Heavy metal translocating P-type atpase
LIS80_RS18120	COG2608	mercury ion transmembrane transporter activity
LIS80_RS18125	COG1937	Protein conserved in bacteria
LIS80_RS18135	COG2819	hydrolase of the alpha beta superfamily
LIS80_RS18140	COG1120	ATPase activity
LIS80_RS18145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS18150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS18155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS18165	COG2169	Transcriptional regulator
LIS80_RS18170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LIS80_RS18175	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LIS80_RS18185	COG2364	Membrane
LIS80_RS18195	COG3300	MHYT domain
LIS80_RS18195	COG5001	Diguanylate cyclase
LIS80_RS18215	COG1380	Effector of murein hydrolase LrgA
LIS80_RS18220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LIS80_RS18240	COG3773	Cell wall hydrolase
LIS80_RS18250	COG1368	sulfuric ester hydrolase activity
LIS80_RS18255	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LIS80_RS18265	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LIS80_RS18285	COG4550	Control of competence regulator ComK, YlbF/YmcA
LIS80_RS18295	COG1013	pyruvate-flavodoxin oxidoreductase activity
LIS80_RS18300	COG0674	pyruvate-flavodoxin oxidoreductase activity
LIS80_RS18300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LIS80_RS18310	COG2359	stage V sporulation protein S
LIS80_RS18315	COG1692	metallophosphoesterase
LIS80_RS18320	COG1418	mRNA catabolic process
LIS80_RS18340	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LIS80_RS18345	COG1426	Protein conserved in bacteria
LIS80_RS18360	COG0300	oxidoreductase activity
LIS80_RS18365	COG0612	Peptidase, M16
LIS80_RS18370	COG0612	Peptidase, M16
LIS80_RS18375	COG1079	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS18380	COG4603	Belongs to the binding-protein-dependent transport system permease family
LIS80_RS18385	COG3845	ABC transporter
LIS80_RS18390	COG1744	ABC transporter substrate-binding protein PnrA-like
LIS80_RS18395	COG2188	Transcriptional regulator
LIS80_RS18400	COG1674	ftsk spoiiie
LIS80_RS18410	COG0740	serine-type endopeptidase activity
LIS80_RS18415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_RS18425	COG0527	aspartate kinase activity
LIS80_RS18430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LIS80_RS18435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIS80_RS18440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIS80_RS18445	COG1873	PFAM PRC-barrel domain
LIS80_RS18450	COG0612	Peptidase, M16
LIS80_RS18455	COG0726	polysaccharide deacetylase
LIS80_RS18470	COG0196	riboflavin kinase activity
LIS80_RS18485	COG1550	Protein conserved in bacteria
LIS80_RS18495	COG1358	cellular component organization or biogenesis
LIS80_RS18500	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LIS80_RS18505	COG0195	Participates in both transcription termination and antitermination
LIS80_RS18525	COG0750	zinc metalloprotease
LIS80_RS18535	COG4589	Belongs to the CDS family
LIS80_RS18550	COG0528	UMP kinase activity
LIS80_RS18580	COG4974	Belongs to the 'phage' integrase family
LIS80_RS18590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LIS80_RS18595	COG0758	DNA mediated transformation
LIS80_RS18600	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LIS80_RS18640	COG1837	Belongs to the UPF0109 family
LIS80_RS18650	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LIS80_RS18660	COG0552	protein localization to endoplasmic reticulum
LIS80_RS18665	COG1196	nuclear chromosome segregation
LIS80_RS18675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LIS80_RS18680	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS18685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LIS80_RS18700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LIS80_RS18705	COG1461	Dihydroxyacetone kinase
LIS80_RS18710	COG1302	Protein conserved in bacteria
LIS80_RS18725	COG1564	THIamine pyrophosphokinase
LIS80_RS18730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LIS80_RS18740	COG0515	serine threonine protein kinase
LIS80_RS18740	COG2815	serine threonine protein kinase
LIS80_RS18745	COG0631	protein serine/threonine phosphatase activity
LIS80_RS18755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LIS80_RS18755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LIS80_RS18765	COG0242	peptide deformylase activity
LIS80_RS18770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LIS80_RS18775	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LIS80_RS18795	COG1561	YicC-like family, N-terminal region
LIS80_RS18800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LIS80_RS18810	COG0006	proline dipeptidase activity
LIS80_RS18830	COG3069	C4-dicarboxylate transmembrane transporter activity
LIS80_RS18895	COG0564	pseudouridine synthase activity
LIS80_RS18915	COG3599	regulation of cell shape
LIS80_RS18920	COG2302	S4 RNA-binding domain
LIS80_RS18925	COG0762	integral membrane protein
LIS80_RS18935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LIS80_RS18945	COG1873	PFAM PRC-barrel domain
LIS80_RS18950	COG1191	sigma factor activity
LIS80_RS18955	COG1191	sigma factor activity
LIS80_RS18965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LIS80_RS18970	COG0849	cell division
LIS80_RS18975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LIS80_RS18990	COG0772	Belongs to the SEDS family
LIS80_RS19005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LIS80_RS19010	COG0768	penicillin binding
LIS80_RS19015	COG0768	penicillin binding
LIS80_RS19020	COG4839	cell division protein FtsL
LIS80_RS19035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LIS80_RS19050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LIS80_RS19055	COG1399	metal-binding, possibly nucleic acid-binding protein
LIS80_RS19065	COG3480	Lon protease (S16) C-terminal proteolytic domain
LIS80_RS19070	COG1752	Esterase of the alpha-beta hydrolase superfamily
LIS80_RS19075	COG3314	Sporulation integral membrane protein YlbJ
LIS80_RS19085	COG0742	ribosomal rna small subunit methyltransferase
LIS80_RS19100	COG3679	Belongs to the UPF0342 family
LIS80_RS19105	COG0406	alpha-ribazole phosphatase activity
LIS80_RS19120	COG2340	Cysteine-rich secretory protein family
LIS80_RS19135	COG3344	reverse transcriptase
LIS80_RS19145	COG3336	cytochrome c oxidase
LIS80_RS19160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LIS80_RS19180	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LIS80_RS19185	COG0772	Belongs to the SEDS family
LIS80_RS19195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LIS80_RS19200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LIS80_RS19210	COG4896	Protein conserved in bacteria
LIS80_RS19225	COG1217	gtp-binding protein TYPA
LIS80_RS19235	COG0483	inositol monophosphate 1-phosphatase activity
LIS80_RS19255	COG1982	Orn Lys Arg decarboxylase major
LIS80_RS19305	COG0022	dehydrogenase e1 component
LIS80_RS19310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_RS19320	COG0242	peptide deformylase activity
LIS80_RS19325	COG0561	phosphatase activity
LIS80_RS19335	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LIS80_RS19340	COG0569	domain protein
LIS80_RS19360	COG0583	DNA-binding transcription factor activity
LIS80_RS19365	COG0517	IMP dehydrogenase activity
LIS80_RS19375	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LIS80_RS19385	COG4703	Protein of unknown function (DUF1797)
LIS80_RS19400	COG2200	EAL domain
LIS80_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS19410	COG1408	metallophosphoesterase
LIS80_RS19420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LIS80_RS19455	COG2814	Major facilitator Superfamily
LIS80_RS19485	COG3209	COG3209 Rhs family protein
LIS80_RS19495	COG2205	protein histidine kinase activity
LIS80_RS19505	COG0436	Aminotransferase
LIS80_RS19510	COG1609	Transcriptional regulator
LIS80_RS19515	COG3833	ABC-type maltose transport systems, permease component
LIS80_RS19520	COG1175	transmembrane transport
LIS80_RS19525	COG2182	Extracellular solute-binding protein
LIS80_RS19535	COG0366	Alpha amylase catalytic
LIS80_RS19540	COG3842	ATPase activity
LIS80_RS19580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LIS80_RS19585	COG0183	Belongs to the thiolase family
LIS80_RS19615	COG1695	Transcriptional regulator
LIS80_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS19640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LIS80_RS19645	COG0436	Aminotransferase
LIS80_RS19680	COG2084	Dehydrogenase
LIS80_RS19690	COG2199	diguanylate cyclase activity
LIS80_RS19695	COG0778	Nitroreductase
LIS80_RS19720	COG1263	PTS System
LIS80_RS19720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LIS80_RS19720	COG2190	(PTS) system
LIS80_RS19725	COG3711	transcriptional antiterminator
LIS80_RS19735	COG2188	Transcriptional regulator
LIS80_RS19745	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LIS80_RS19770	COG1547	Domain of unknown function (DUF309)
LIS80_RS19775	COG0456	acetyltransferase
LIS80_RS19785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LIS80_RS19790	COG4086	secreted protein
LIS80_RS19795	COG0561	phosphatase activity
LIS80_RS19800	COG0697	spore germination
LIS80_RS19815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_RS19840	COG0733	neurotransmitter:sodium symporter activity
LIS80_RS19860	COG1686	Belongs to the peptidase S11 family
LIS80_RS19865	COG1725	Transcriptional regulator
LIS80_RS19870	COG1131	(ABC) transporter
LIS80_RS19885	COG1846	Transcriptional regulator
LIS80_RS19900	COG0598	Magnesium transport protein CorA
LIS80_RS19925	COG4974	Belongs to the 'phage' integrase family
LIS80_RS19935	COG0735	belongs to the Fur family
LIS80_RS19940	COG1300	Membrane
LIS80_RS19960	COG0667	Aldo Keto reductase
LIS80_RS19965	COG0656	L-ascorbic acid biosynthetic process
LIS80_RS19970	COG0456	acetyltransferase
LIS80_RS19970	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LIS80_RS19980	COG0737	Belongs to the 5'-nucleotidase family
LIS80_RS19980	COG4085	toxin activity
LIS80_RS19980	COG1525	nuclease
LIS80_RS19990	COG0596	Alpha beta hydrolase
LIS80_RS19995	COG2056	Na+-H+ antiporter family
LIS80_RS20000	COG1609	Transcriptional regulator
LIS80_RS20005	COG0456	acetyltransferase
LIS80_RS20010	COG1073	alpha beta
LIS80_RS20025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIS80_RS20025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LIS80_RS20030	COG0307	riboflavin synthase, alpha
LIS80_RS20055	COG4106	trans-aconitate 2-methyltransferase activity
LIS80_RS20060	COG1073	alpha beta
LIS80_RS20060	COG2226	methyltransferase
LIS80_RS20075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LIS80_RS20085	COG1757	Na H antiporter
LIS80_RS20090	COG0737	Belongs to the 5'-nucleotidase family
LIS80_RS20100	COG1522	sequence-specific DNA binding
LIS80_RS20120	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LIS80_RS20145	COG0300	oxidoreductase activity
LIS80_RS20150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS20155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_RS20160	COG1760	l-serine dehydratase
LIS80_RS20165	COG1760	l-serine dehydratase
LIS80_RS20195	COG2195	Cleaves the N-terminal amino acid of tripeptides
LIS80_RS20200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS20215	COG1376	ErfK ybiS ycfS ynhG family protein
LIS80_RS20220	COG4129	membrane
LIS80_RS20225	COG1126	abc transporter atp-binding protein
LIS80_RS20230	COG0765	amino acid transport
LIS80_RS20235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LIS80_RS20250	COG2323	membrane
LIS80_RS20255	COG0772	Belongs to the SEDS family
LIS80_RS20260	COG0508	dehydrogenase complex catalyzes the overall conversion of
LIS80_RS20265	COG0022	dehydrogenase e1 component
LIS80_RS20270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LIS80_RS20275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LIS80_RS20290	COG0280	phosphate acetyltransferase
LIS80_RS20295	COG3290	protein histidine kinase activity
LIS80_RS20295	COG3829	transcription factor binding
LIS80_RS20305	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_RS20310	COG3093	addiction module antidote protein HigA
LIS80_RS20315	COG0745	RESPONSE REGULATOR receiver
LIS80_RS20320	COG0750	zinc metalloprotease
LIS80_RS20325	COG0497	DNA recombination
LIS80_RS20335	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LIS80_RS20345	COG0142	geranyltranstransferase activity
LIS80_RS20370	COG1302	Protein conserved in bacteria
LIS80_RS20375	COG0439	Biotin carboxylase
LIS80_RS20380	COG0511	ligase activity, forming carbon-carbon bonds
LIS80_RS20425	COG3854	ATPases associated with a variety of cellular activities
LIS80_RS20450	COG0006	proline dipeptidase activity
LIS80_RS20465	COG3872	metal-dependent enzyme
LIS80_RS20495	COG0095	Lipoate-protein ligase
LIS80_RS20500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_RS20505	COG1609	Transcriptional regulator
LIS80_RS20515	COG2076	Multidrug Resistance protein
LIS80_RS20520	COG2076	Multidrug Resistance protein
LIS80_RS20555	COG1131	(ABC) transporter
LIS80_RS20560	COG1725	Transcriptional regulator
LIS80_RS20590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_RS20645	COG4970	Tfp pilus assembly protein FimT
LIS80_RS20655	COG1459	type II secretion system
LIS80_RS20660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LIS80_RS20715	COG0646	methionine synthase
LIS80_RS20715	COG1410	methionine synthase
LIS80_RS20720	COG0646	methionine synthase
LIS80_RS20720	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LIS80_RS20725	COG0626	cystathionine gamma-synthase activity
LIS80_RS20730	COG0626	cystathionine gamma-synthase activity
LIS80_RS20750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS20760	COG1940	carbohydrate kinase activity
LIS80_RS20765	COG4483	Protein conserved in bacteria
LIS80_RS20770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LIS80_RS20775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LIS80_RS20780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LIS80_RS20785	COG0704	Plays a role in the regulation of phosphate uptake
LIS80_RS20795	COG0581	inorganic phosphate transmembrane transporter activity
LIS80_RS20800	COG0573	inorganic phosphate transmembrane transporter activity
LIS80_RS20805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LIS80_RS20810	COG0768	penicillin binding
LIS80_RS20815	COG0477	Major facilitator Superfamily
LIS80_RS20820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_RS20845	COG0735	belongs to the Fur family
LIS80_RS20850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LIS80_RS20855	COG1121	(ABC) transporter
LIS80_RS20860	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS20890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LIS80_RS20895	COG2384	SAM-dependent methyltransferase
LIS80_RS20900	COG2010	Cytochrome c
LIS80_RS20905	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LIS80_RS20910	COG0358	DNA primase activity
LIS80_RS20925	COG0517	IMP dehydrogenase activity
LIS80_RS20940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LIS80_RS20945	COG0295	cytidine deaminase activity
LIS80_RS20950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LIS80_RS20960	COG1480	7TM receptor with intracellular HD hydrolase
LIS80_RS20965	COG1702	phosphate starvation-inducible protein PhoH
LIS80_RS20980	COG1610	YqeY-like protein
LIS80_RS20985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LIS80_RS20990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LIS80_RS20995	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LIS80_RS21025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LIS80_RS21030	COG1733	regulation of RNA biosynthetic process
LIS80_RS21055	COG1466	dna polymerase III delta subunit
LIS80_RS21065	COG0658	competence protein
LIS80_RS21065	COG2333	competence protein COMEC
LIS80_RS21070	COG2131	deaminase
LIS80_RS21075	COG1555	photosystem II stabilization
LIS80_RS21075	COG1596	polysaccharide export
LIS80_RS21080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LIS80_RS21085	COG2226	methyltransferase
LIS80_RS21090	COG0799	negative regulation of ribosome biogenesis
LIS80_RS21095	COG1713	HD superfamily hydrolase involved in NAD metabolism
LIS80_RS21105	COG1534	Rna-binding protein
LIS80_RS21115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LIS80_RS21120	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LIS80_RS21145	COG1595	DNA-templated transcription, initiation
LIS80_RS21155	COG2357	RelA SpoT domain protein
LIS80_RS21165	COG1785	Belongs to the alkaline phosphatase family
LIS80_RS21170	COG0456	acetyltransferase
LIS80_RS21175	COG2267	carboxylic ester hydrolase activity
LIS80_RS21210	COG1404	Belongs to the peptidase S8 family
LIS80_RS21215	COG3186	Phenylalanine-4-hydroxylase
LIS80_RS21225	COG2514	catechol 2,3-dioxygenase activity
LIS80_RS21230	COG2259	Doxx family
LIS80_RS21270	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LIS80_RS21280	COG1012	belongs to the aldehyde dehydrogenase family
LIS80_RS21280	COG1454	alcohol dehydrogenase
LIS80_RS21285	COG0626	cystathionine gamma-synthase activity
LIS80_RS21290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LIS80_RS21315	COG0768	penicillin binding
LIS80_RS21330	COG0826	peptidase U32
LIS80_RS21335	COG0826	peptidase U32
LIS80_RS21340	COG4122	O-methyltransferase activity
LIS80_RS21345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LIS80_RS21375	COG0628	permease
LIS80_RS21395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LIS80_RS21410	COG1104	cysteine desulfurase activity
LIS80_RS21415	COG1959	2 iron, 2 sulfur cluster binding
LIS80_RS21420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LIS80_RS21430	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LIS80_RS21460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LIS80_RS21470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIS80_RS21470	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LIS80_RS21475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LIS80_RS21480	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIS80_RS21480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LIS80_RS21490	COG2244	polysaccharide biosynthetic process
LIS80_RS21495	COG2323	membrane
LIS80_RS21505	COG1862	Preprotein translocase
LIS80_RS21535	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LIS80_RS21550	COG0697	spore germination
LIS80_RS21555	COG0640	Transcriptional regulator
LIS80_RS21580	COG0157	Belongs to the NadC ModD family
LIS80_RS21585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LIS80_RS21590	COG1104	cysteine desulfurase activity
LIS80_RS21595	COG1827	regulation of RNA biosynthetic process
LIS80_RS21600	COG2258	MOSC domain
LIS80_RS21605	COG0077	Prephenate dehydratase
LIS80_RS21610	COG0577	efflux transmembrane transporter activity
LIS80_RS21615	COG0577	efflux transmembrane transporter activity
LIS80_RS21620	COG1136	(ABC) transporter
LIS80_RS21625	COG5002	protein histidine kinase activity
LIS80_RS21630	COG0745	RESPONSE REGULATOR receiver
LIS80_RS21640	COG3290	protein histidine kinase activity
LIS80_RS21650	COG2868	ribosomal protein
LIS80_RS21655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LIS80_RS21660	COG1530	ribonuclease E activity
LIS80_RS21665	COG1994	Peptidase M50
LIS80_RS21670	COG0739	heme binding
LIS80_RS21675	COG2894	cell division
LIS80_RS21695	COG1077	Cell shape determining protein MreB Mrl
LIS80_RS21710	COG0477	Major facilitator Superfamily
LIS80_RS21715	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS21750	COG0285	dihydrofolate synthase activity
LIS80_RS21765	COG1388	LysM domain
LIS80_RS21775	COG0113	porphobilinogen synthase activity
LIS80_RS21780	COG1587	Uroporphyrinogen-III synthase
LIS80_RS21790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LIS80_RS21800	COG1846	Transcriptional regulator
LIS80_RS21805	COG1764	response to oxidative stress
LIS80_RS21820	COG1067	ATP-dependent peptidase activity
LIS80_RS21820	COG0470	DNA polymerase III
LIS80_RS21960	COG0622	Phosphoesterase
LIS80_RS21975	COG5401	PFAM Sporulation and spore germination
LIS80_RS21995	COG1309	transcriptional regulator
LIS80_RS22035	COG1196	nuclear chromosome segregation
LIS80_RS22060	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LIS80_RS22060	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LIS80_RS22105	COG2197	response regulator
LIS80_RS22110	COG2233	PERMEase
LIS80_RS22115	COG0402	S-adenosylhomocysteine deaminase activity
LIS80_RS22120	COG1983	PspC domain protein
LIS80_RS22125	COG1396	sequence-specific DNA binding
LIS80_RS22130	COG0697	spore germination
LIS80_RS22140	COG1959	2 iron, 2 sulfur cluster binding
LIS80_RS22145	COG1668	transmembrane transport
LIS80_RS22150	COG4152	abc transporter atp-binding protein
LIS80_RS22155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
LIS80_RS22160	COG1360	Flagellar Motor Protein
LIS80_RS22165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LIS80_RS22170	COG1876	peptidase activity
LIS80_RS22175	COG0824	Thioesterase
LIS80_RS22180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LIS80_RS22185	COG1053	succinate dehydrogenase
LIS80_RS22190	COG2009	succinate dehydrogenase
LIS80_RS22195	COG1719	4-vinyl reductase, 4VR
LIS80_RS22205	COG3118	belongs to the thioredoxin family
LIS80_RS22210	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LIS80_RS22215	COG2086	electron transfer activity
LIS80_RS22220	COG1024	Enoyl-CoA hydratase
LIS80_RS22225	COG1309	transcriptional regulator
LIS80_RS22230	COG0318	PFAM AMP-dependent synthetase and ligase
LIS80_RS22240	COG2318	DinB family
LIS80_RS22265	COG1131	(ABC) transporter
LIS80_RS22270	COG2205	protein histidine kinase activity
LIS80_RS22275	COG0745	RESPONSE REGULATOR receiver
LIS80_RS22285	COG4895	conserved protein (DUF2196)
LIS80_RS22290	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LIS80_RS22305	COG4509	Sortase family
LIS80_RS22310	COG1120	ATPase activity
LIS80_RS22325	COG5386	Cell surface protein
LIS80_RS22330	COG5386	Cell surface protein
LIS80_RS22335	COG1114	Component of the transport system for branched-chain amino acids
LIS80_RS22340	COG1187	pseudouridine synthase activity
LIS80_RS22350	COG1796	DNA polymerase
LIS80_RS22350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LIS80_RS22355	COG1286	toxin biosynthetic process
LIS80_RS22400	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LIS80_RS22410	COG1418	mRNA catabolic process
LIS80_RS22420	COG2814	Major facilitator Superfamily
LIS80_RS22425	COG1566	PFAM secretion protein HlyD family protein
LIS80_RS22430	COG1309	transcriptional regulator
LIS80_RS22435	COG1363	Peptidase, m42
LIS80_RS22460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LIS80_RS22470	COG1484	DNA-dependent DNA replication
LIS80_RS22475	COG3611	Membrane attachment protein
LIS80_RS22485	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LIS80_RS22490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIS80_RS22495	COG0237	dephospho-CoA kinase activity
LIS80_RS22500	COG1971	Probably functions as a manganese efflux pump
LIS80_RS22510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_RS22510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LIS80_RS22515	COG5002	protein histidine kinase activity
LIS80_RS22520	COG0745	RESPONSE REGULATOR receiver
LIS80_RS22540	COG0538	isocitrate dehydrogenase activity
LIS80_RS22545	COG0372	Belongs to the citrate synthase family
LIS80_RS22555	COG0628	permease
LIS80_RS22560	COG3030	protein affecting phage T7 exclusion by the F plasmid
LIS80_RS22585	COG1725	Transcriptional regulator
LIS80_RS22590	COG0281	malic enzyme
LIS80_RS22595	COG0587	DNA-directed DNA polymerase activity
LIS80_RS22610	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LIS80_RS22635	COG4109	DRTGG domain
LIS80_RS22650	COG0006	proline dipeptidase activity
LIS80_RS22690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS22695	COG0662	Cupin 2, conserved barrel domain protein
LIS80_RS22715	COG1028	Short-chain dehydrogenase reductase Sdr
LIS80_RS22720	COG0589	response to stress
LIS80_RS22790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS22815	COG0827	DNA restriction-modification system
LIS80_RS22820	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LIS80_RS22825	COG3874	Sporulation protein YtfJ
LIS80_RS22840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LIS80_RS22850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_RS22865	COG1104	cysteine desulfurase activity
LIS80_RS22875	COG0583	DNA-binding transcription factor activity
LIS80_RS22880	COG0697	spore germination
LIS80_RS22885	COG1309	transcriptional regulator
LIS80_RS22890	COG1956	GAF domain-containing protein
LIS80_RS22895	COG0626	cystathionine gamma-synthase activity
LIS80_RS22925	COG1595	DNA-templated transcription, initiation
LIS80_RS22935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LIS80_RS22940	COG0454	-acetyltransferase
LIS80_RS22945	COG0517	IMP dehydrogenase activity
LIS80_RS22950	COG0123	including yeast histone deacetylase and acetoin utilization protein
LIS80_RS22955	COG2267	carboxylic ester hydrolase activity
LIS80_RS22965	COG0745	RESPONSE REGULATOR receiver
LIS80_RS23010	COG1609	Transcriptional regulator
LIS80_RS23015	COG4851	CamS sex pheromone cAM373 precursor
LIS80_RS23020	COG3118	belongs to the thioredoxin family
LIS80_RS23030	COG2309	aminopeptidase activity
LIS80_RS23050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS23065	COG1674	ftsk spoiiie
LIS80_RS23075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LIS80_RS23085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS23090	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LIS80_RS23095	COG1363	Peptidase, m42
LIS80_RS23105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS23120	COG0510	thiamine kinase activity
LIS80_RS23125	COG1523	belongs to the glycosyl hydrolase 13 family
LIS80_RS23135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LIS80_RS23140	COG1349	DNA-binding transcription factor activity
LIS80_RS23145	COG1187	pseudouridine synthase activity
LIS80_RS23150	COG2244	polysaccharide biosynthetic process
LIS80_RS23155	COG2081	HI0933 family
LIS80_RS23160	COG2814	Major facilitator Superfamily
LIS80_RS23170	COG3832	glyoxalase III activity
LIS80_RS23190	COG1329	Transcriptional regulator
LIS80_RS23215	COG0314	molybdopterin synthase activity
LIS80_RS23230	COG1763	Mo-molybdopterin cofactor biosynthetic process
LIS80_RS23235	COG0303	'Molybdopterin
LIS80_RS23245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LIS80_RS23250	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LIS80_RS23270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LIS80_RS23280	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LIS80_RS23320	COG2814	Major facilitator Superfamily
LIS80_RS23325	COG0475	glutathione-regulated potassium exporter activity
LIS80_RS23330	COG0490	domain, Protein
LIS80_RS23335	COG0582	viral genome integration into host DNA
LIS80_RS23345	COG1136	(ABC) transporter
LIS80_RS23365	COG1242	4 iron, 4 sulfur cluster binding
LIS80_RS23370	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LIS80_RS23375	COG4152	abc transporter atp-binding protein
LIS80_RS23385	COG1794	racemase activity, acting on amino acids and derivatives
LIS80_RS23410	COG2267	carboxylic ester hydrolase activity
LIS80_RS23415	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LIS80_RS23420	COG0671	phosphoesterase, PA-phosphatase related
LIS80_RS23425	COG0438	transferase activity, transferring glycosyl groups
LIS80_RS23435	COG0521	Mo-molybdopterin cofactor biosynthetic process
LIS80_RS23450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS23495	COG5002	protein histidine kinase activity
LIS80_RS23500	COG4191	Histidine kinase
LIS80_RS23505	COG2267	carboxylic ester hydrolase activity
LIS80_RS23510	COG1368	sulfuric ester hydrolase activity
LIS80_RS23535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LIS80_RS23540	COG1116	anion transmembrane transporter activity
LIS80_RS23545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LIS80_RS23570	COG0494	nUDIX hydrolase
LIS80_RS23605	COG0288	reversible hydration of carbon dioxide
LIS80_RS23610	COG1271	oxidase subunit
LIS80_RS23615	COG1294	oxidase, subunit
LIS80_RS23635	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS23660	COG1842	Phage shock protein A
LIS80_RS23695	COG5002	protein histidine kinase activity
LIS80_RS23700	COG0745	RESPONSE REGULATOR receiver
LIS80_RS23730	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LIS80_RS23735	COG1597	lipid kinase activity
LIS80_RS23755	COG0577	efflux transmembrane transporter activity
LIS80_RS23760	COG1136	(ABC) transporter
LIS80_RS23775	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS23785	COG4977	sequence-specific DNA binding
LIS80_RS23795	COG0577	efflux transmembrane transporter activity
LIS80_RS23800	COG1136	(ABC) transporter
LIS80_RS23805	COG3708	Transcriptional regulator
LIS80_RS23805	COG2207	Transcriptional regulator
LIS80_RS23810	COG5658	integral membrane protein
LIS80_RS23815	COG0640	Transcriptional regulator
LIS80_RS23820	COG0745	RESPONSE REGULATOR receiver
LIS80_RS23825	COG2205	protein histidine kinase activity
LIS80_RS23830	COG0577	efflux transmembrane transporter activity
LIS80_RS23835	COG0577	efflux transmembrane transporter activity
LIS80_RS23840	COG1136	(ABC) transporter
LIS80_RS23845	COG0577	efflux transmembrane transporter activity
LIS80_RS23860	COG2188	Transcriptional regulator
LIS80_RS23880	COG3964	amidohydrolase
LIS80_RS23900	COG4948	Mandelate Racemase Muconate Lactonizing
LIS80_RS23910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LIS80_RS23915	COG0596	Alpha beta hydrolase
LIS80_RS23925	COG1169	isochorismate synthase
LIS80_RS23930	COG1575	Belongs to the MenA family. Type 1 subfamily
LIS80_RS23935	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LIS80_RS23955	COG0058	SHG alpha-glucan phosphorylase activity
LIS80_RS23965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LIS80_RS23985	COG1404	Belongs to the peptidase S8 family
LIS80_RS24085	COG0544	peptidyl-prolyl cis-trans isomerase activity
LIS80_RS24120	COG1285	pathogenesis
LIS80_RS24125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LIS80_RS24140	COG2155	Conserved Protein
LIS80_RS24145	COG1098	S1 RNA binding domain
LIS80_RS24150	COG0436	Aminotransferase
LIS80_RS24155	COG1522	sequence-specific DNA binding
LIS80_RS24160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LIS80_RS24165	COG2267	carboxylic ester hydrolase activity
LIS80_RS24175	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LIS80_RS24195	COG5018	Exonuclease
LIS80_RS24200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_RS24220	COG2050	protein possibly involved in aromatic compounds catabolism
LIS80_RS24230	COG1268	BioY protein
LIS80_RS24235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LIS80_RS24240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIS80_RS24255	COG3584	3D domain protein
LIS80_RS24270	COG1252	NADH dehydrogenase
LIS80_RS24280	COG3708	Transcriptional regulator
LIS80_RS24295	COG1683	Conserved Protein
LIS80_RS24310	COG0316	Belongs to the HesB IscA family
LIS80_RS24325	COG1252	NADH dehydrogenase
LIS80_RS24340	COG0390	transport system, permease component
LIS80_RS24345	COG2824	Alkylphosphonate utilization operon protein PhnA
LIS80_RS24385	COG4837	Protein of unknown function (DUF1462)
LIS80_RS24390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LIS80_RS24400	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LIS80_RS24405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LIS80_RS24420	COG2249	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS24430	COG0647	UMP catabolic process
LIS80_RS24440	COG2445	Protein of unknown function DUF86
LIS80_RS24445	COG1494	fructose-1,6-bisphosphatase
LIS80_RS24460	COG4470	Protein conserved in bacteria
LIS80_RS24470	COG0789	Transcriptional regulator
LIS80_RS24475	COG4377	Putative membrane peptidase family (DUF2324)
LIS80_RS24500	COG0739	heme binding
LIS80_RS24510	COG3377	Domain of unknown function (DUF1805)
LIS80_RS24515	COG0737	Belongs to the 5'-nucleotidase family
LIS80_RS24520	COG0719	Fe-S assembly protein
LIS80_RS24525	COG0822	iron-sulfur transferase activity
LIS80_RS24530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LIS80_RS24535	COG0719	Fe-S assembly protein
LIS80_RS24540	COG0396	ATPase activity
LIS80_RS24545	COG1464	Belongs to the NlpA lipoprotein family
LIS80_RS24550	COG1464	Belongs to the NlpA lipoprotein family
LIS80_RS24555	COG2011	ABC-type metal ion transport system permease component
LIS80_RS24560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LIS80_RS24570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LIS80_RS24575	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LIS80_RS24585	COG1393	Belongs to the ArsC family
LIS80_RS24640	COG1396	sequence-specific DNA binding
LIS80_RS24650	COG1309	transcriptional regulator
LIS80_RS24655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LIS80_RS24660	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS24665	COG0183	Belongs to the thiolase family
LIS80_RS24670	COG1250	3-hydroxyacyl-CoA dehydrogenase
LIS80_RS24670	COG1024	Enoyl-CoA hydratase
LIS80_RS24680	COG1686	Belongs to the peptidase S11 family
LIS80_RS24695	COG0011	TIGRFAM Protein of
LIS80_RS24700	COG0840	transmembrane signaling receptor activity
LIS80_RS24725	COG2814	Major facilitator Superfamily
LIS80_RS24730	COG0531	amino acid
LIS80_RS24755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LIS80_RS24790	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS24800	COG1376	ErfK ybiS ycfS ynhG family protein
LIS80_RS24805	COG0745	RESPONSE REGULATOR receiver
LIS80_RS24810	COG5002	protein histidine kinase activity
LIS80_RS24840	COG0840	transmembrane signaling receptor activity
LIS80_RS24845	COG2151	metal-sulfur cluster biosynthetic enzyme
LIS80_RS24850	COG3227	Zinc metalloprotease (Elastase)
LIS80_RS24855	COG1741	Belongs to the pirin family
LIS80_RS24870	COG0475	glutathione-regulated potassium exporter activity
LIS80_RS24875	COG0490	domain, Protein
LIS80_RS24880	COG1115	amino acid carrier protein
LIS80_RS24885	COG0783	Belongs to the Dps family
LIS80_RS24900	COG1611	Belongs to the LOG family
LIS80_RS24920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS24925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS24930	COG1115	amino acid carrier protein
LIS80_RS24935	COG1115	amino acid carrier protein
LIS80_RS24940	COG2910	NAD(P)H-binding
LIS80_RS24955	COG0656	L-ascorbic acid biosynthetic process
LIS80_RS24960	COG2814	Major facilitator Superfamily
LIS80_RS24965	COG1733	regulation of RNA biosynthetic process
LIS80_RS24975	COG1252	NADH dehydrogenase
LIS80_RS24980	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LIS80_RS25010	COG3290	protein histidine kinase activity
LIS80_RS25010	COG0840	transmembrane signaling receptor activity
LIS80_RS25045	COG0488	(ABC) transporter
LIS80_RS25050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LIS80_RS25095	COG1136	(ABC) transporter
LIS80_RS25115	COG0586	Pfam SNARE associated Golgi protein
LIS80_RS25120	COG3963	phosphatidate phosphatase activity
LIS80_RS25170	COG3708	Transcriptional regulator
LIS80_RS25170	COG2207	Transcriptional regulator
LIS80_RS25185	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LIS80_RS25190	COG2814	Major facilitator Superfamily
LIS80_RS25200	COG0640	Transcriptional regulator
LIS80_RS25205	COG2311	Membrane
LIS80_RS25225	COG0557	exoribonuclease II activity
LIS80_RS25230	COG1647	Serine aminopeptidase, S33
LIS80_RS25235	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LIS80_RS25240	COG1346	cytolysis
LIS80_RS25275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LIS80_RS25290	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LIS80_RS25300	COG1668	transmembrane transport
LIS80_RS25305	COG4152	abc transporter atp-binding protein
LIS80_RS25325	COG0142	geranyltranstransferase activity
LIS80_RS25335	COG4585	Histidine kinase
LIS80_RS25340	COG2197	response regulator
LIS80_RS25405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_RS25420	COG2323	membrane
LIS80_RS25430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS25440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LIS80_RS25450	COG1051	belongs to the nudix hydrolase family
LIS80_RS25460	COG0492	ferredoxin-NADP+ reductase activity
LIS80_RS25465	COG0457	Tetratricopeptide repeat
LIS80_RS25470	COG0110	maltose O-acetyltransferase activity
LIS80_RS25490	COG1950	PFAM Membrane protein of
LIS80_RS25500	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LIS80_RS25515	COG0789	Transcriptional regulator
LIS80_RS25550	COG0583	DNA-binding transcription factor activity
LIS80_RS25560	COG0655	NAD(P)H dehydrogenase (quinone) activity
LIS80_RS25575	COG1132	(ABC) transporter
LIS80_RS25580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_RS25585	COG3409	Peptidoglycan-binding domain 1 protein
LIS80_RS25585	COG0793	Belongs to the peptidase S41A family
LIS80_RS25590	COG2177	Part of the ABC transporter FtsEX involved in
LIS80_RS25595	COG2884	Cell division ATP-binding protein ftsE
LIS80_RS25615	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LIS80_RS25620	COG1278	Cold shock
LIS80_RS25625	COG1040	competence protein
LIS80_RS25630	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LIS80_RS25635	COG1388	LysM domain
LIS80_RS25635	COG0791	NLP P60 protein
LIS80_RS25640	COG1733	regulation of RNA biosynthetic process
LIS80_RS25645	COG1307	EDD domain protein, DegV family
LIS80_RS25650	COG1739	Uncharacterized protein family UPF0029
LIS80_RS25670	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LIS80_RS25675	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LIS80_RS25680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LIS80_RS25690	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LIS80_RS25690	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LIS80_RS25710	COG1486	melibiose metabolic process
LIS80_RS25715	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_RS25720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_RS25730	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LIS80_RS25750	COG1447	Phosphotransferase system cellobiose-specific component IIA
LIS80_RS25760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LIS80_RS25765	COG1301	dicarboxylic acid transport
LIS80_RS25775	COG0346	lactoylglutathione lyase activity
LIS80_RS25795	COG1511	domain protein
LIS80_RS25800	COG0583	DNA-binding transcription factor activity
LIS80_RS25805	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LIS80_RS25815	COG1271	oxidase subunit
LIS80_RS25820	COG1294	oxidase, subunit
LIS80_RS25825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LIS80_RS25835	COG1620	l-lactate permease
LIS80_RS25845	COG2389	metal-binding protein
LIS80_RS25855	COG1368	sulfuric ester hydrolase activity
LIS80_RS25865	COG1388	LysM domain
LIS80_RS25865	COG0791	NLP P60 protein
LIS80_RS25870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LIS80_RS25880	COG1215	transferase activity, transferring glycosyl groups
LIS80_RS25885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_RS25890	COG3584	3D domain protein
LIS80_RS25890	COG1388	LysM domain
LIS80_RS25915	COG4715	Zinc finger, swim domain protein
LIS80_RS25920	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LIS80_RS25960	COG0577	efflux transmembrane transporter activity
LIS80_RS25965	COG1136	(ABC) transporter
LIS80_RS25990	COG5002	protein histidine kinase activity
LIS80_RS25995	COG0745	RESPONSE REGULATOR receiver
LIS80_RS26000	COG1482	cell wall glycoprotein biosynthetic process
LIS80_RS26005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS26005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_RS26005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LIS80_RS26010	COG3711	transcriptional antiterminator
LIS80_RS26010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LIS80_RS26015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LIS80_RS26035	COG0456	acetyltransferase
LIS80_RS26055	COG3475	LICD family
LIS80_RS26065	COG1316	TRANSCRIPTIONal
LIS80_RS26070	COG1482	cell wall glycoprotein biosynthetic process
LIS80_RS26075	COG0662	Cupin 2, conserved barrel domain protein
LIS80_RS26075	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LIS80_RS26095	COG0463	Glycosyl transferase, family 2
LIS80_RS26105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LIS80_RS26110	COG4464	protein tyrosine phosphatase activity
LIS80_RS26115	COG0489	protein tyrosine kinase activity
LIS80_RS26120	COG3944	biosynthesis protein
LIS80_RS26125	COG0489	protein tyrosine kinase activity
LIS80_RS26140	COG1609	Transcriptional regulator
LIS80_RS26150	COG0739	heme binding
LIS80_RS26165	COG3279	Response regulator of the LytR AlgR family
LIS80_RS26170	COG2385	sporulation resulting in formation of a cellular spore
LIS80_RS26185	COG4836	Membrane
LIS80_RS26190	COG1007	ATP synthesis coupled electron transport
LIS80_RS26195	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIS80_RS26200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LIS80_RS26240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LIS80_RS26255	COG5001	Diguanylate cyclase
LIS80_RS26255	COG3300	MHYT domain
LIS80_RS26305	COG0356	it plays a direct role in the translocation of protons across the membrane
LIS80_RS26340	COG0698	ribose 5-phosphate isomerase
LIS80_RS26350	COG2190	(PTS) system
LIS80_RS26355	COG2259	Doxx family
LIS80_RS26360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LIS80_RS26375	COG0009	L-threonylcarbamoyladenylate synthase
LIS80_RS26390	COG2890	protein-(glutamine-N5) methyltransferase activity
LIS80_RS26410	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LIS80_RS26415	COG1494	fructose-1,6-bisphosphatase
LIS80_RS26435	COG4821	SIS domain
LIS80_RS26455	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS26460	COG1960	acyl-CoA dehydrogenase activity
LIS80_RS26465	COG1250	3-hydroxyacyl-CoA dehydrogenase
LIS80_RS26470	COG0183	Belongs to the thiolase family
LIS80_RS26475	COG2181	nitrate reductase activity
LIS80_RS26475	COG0247	lactate metabolic process
LIS80_RS26480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS26490	COG5001	Diguanylate cyclase
LIS80_RS26490	COG3300	MHYT domain
LIS80_RS26510	COG2197	response regulator
LIS80_RS26515	COG4585	Histidine kinase
LIS80_RS26520	COG0842	Transport permease protein
LIS80_RS26525	COG1131	(ABC) transporter
LIS80_RS26530	COG0024	Methionine aminopeptidase
LIS80_RS26540	COG2234	aminopeptidase activity
LIS80_RS26560	COG1595	DNA-templated transcription, initiation
LIS80_RS26570	COG4506	Protein conserved in bacteria
LIS80_RS26575	COG1619	proteins homologs of microcin C7 resistance protein MccF
LIS80_RS26600	COG2814	Major facilitator Superfamily
LIS80_RS26605	COG0789	Transcriptional regulator
LIS80_RS26610	COG0584	glycerophosphoryl diester phosphodiesterase
LIS80_RS26615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LIS80_RS26625	COG1994	Peptidase M50
LIS80_RS26635	COG1078	dGTPase activity
LIS80_RS26640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LIS80_RS26645	COG1120	ATPase activity
LIS80_RS26650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS26655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LIS80_RS26675	COG0095	Lipoate-protein ligase
LIS80_RS26680	COG0280	phosphate acetyltransferase
LIS80_RS26695	COG3773	Cell wall hydrolase
LIS80_RS26705	COG2363	Small membrane protein
LIS80_RS26715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LIS80_RS26720	COG2233	PERMEase
LIS80_RS26725	COG0561	phosphatase activity
LIS80_RS26730	COG2814	Major facilitator Superfamily
LIS80_RS26740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LIS80_RS26745	COG1131	(ABC) transporter
LIS80_RS26750	COG2755	lipolytic protein G-D-S-L family
LIS80_RS26755	COG1609	Transcriptional regulator
LIS80_RS26765	COG0460	homoserine dehydrogenase
LIS80_RS26775	COG2873	o-acetylhomoserine
LIS80_RS26780	COG1011	Hydrolase
LIS80_RS26785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LIS80_RS26795	COG2197	response regulator
LIS80_RS26800	COG2203	Gaf domain
LIS80_RS26800	COG4585	Histidine kinase
LIS80_RS26805	COG0351	phosphomethylpyrimidine kinase
LIS80_RS26810	COG3706	GGDEF domain
LIS80_RS26815	COG2879	small protein
LIS80_RS26820	COG1966	Carbon starvation protein
LIS80_RS26825	COG3279	Response regulator of the LytR AlgR family
LIS80_RS26830	COG0477	Major facilitator Superfamily
LIS80_RS26840	COG0438	transferase activity, transferring glycosyl groups
LIS80_RS26855	COG0840	transmembrane signaling receptor activity
LIS80_RS26865	COG1607	acyl-coa hydrolase
LIS80_RS26870	COG1216	Glycosyl transferase, family 2
LIS80_RS26885	COG1216	Glycosyl transferase, family 2
LIS80_RS26900	COG0488	(ABC) transporter
LIS80_RS26905	COG1309	transcriptional regulator
LIS80_RS26910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LIS80_RS26915	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_RS26915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LIS80_RS26920	COG0628	permease
LIS80_RS26935	COG3279	Response regulator of the LytR AlgR family
LIS80_RS26940	COG3275	phosphorelay sensor kinase activity
LIS80_RS26950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LIS80_RS26955	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LIS80_RS26960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LIS80_RS27005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LIS80_RS27010	COG1272	protein, Hemolysin III
LIS80_RS27030	COG1164	Oligoendopeptidase f
LIS80_RS27050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LIS80_RS27055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LIS80_RS27060	COG4853	Protein conserved in bacteria
LIS80_RS27065	COG4863	YycH protein
LIS80_RS27070	COG5002	protein histidine kinase activity
LIS80_RS27075	COG0745	RESPONSE REGULATOR receiver
LIS80_RS27105	COG0305	Participates in initiation and elongation during chromosome replication
LIS80_RS27115	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LIS80_RS27120	COG4241	membrane
LIS80_RS27130	COG0629	single-stranded DNA binding
LIS80_RS27140	COG0012	GTP binding
LIS80_RS27145	COG4481	Protein conserved in bacteria
LIS80_RS27150	COG0668	transmembrane transport
LIS80_RS27160	COG1475	DNA binding
LIS80_RS27165	COG1192	Involved in chromosome partitioning
LIS80_RS27190	COG1847	R3H domain protein
LIS80_RS27195	COG0706	membrane insertase activity
LIS80_RS27205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LIS80_RS27345	COG2311	Membrane
LIS80_RS27385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LIS80_RS27415	COG2002	toxin-antitoxin pair type II binding
LIS80_RS27425	COG4974	Belongs to the 'phage' integrase family
LIS80_RS27500	COG3708	Transcriptional regulator
LIS80_RS27500	COG2207	Transcriptional regulator
LIS80_RS27575	COG3655	Transcriptional regulator
LIS80_RS27590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LIS80_RS27595	COG2323	membrane
LIS80_RS27620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LIS80_RS27635	COG2323	membrane
LIS80_RS27660	COG0697	spore germination
LIS80_RS27675	COG1733	regulation of RNA biosynthetic process
LIS80_RS27685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LIS80_RS27695	COG1181	Belongs to the D-alanine--D-alanine ligase family
LIS80_RS27695	COG2918	glutathione biosynthetic process
LIS80_RS27735	COG1335	isochorismatase
LIS80_RS27740	COG4990	cell redox homeostasis
LIS80_RS27745	COG0745	RESPONSE REGULATOR receiver
LIS80_RS27780	COG1196	nuclear chromosome segregation
LIS80_RS27815	COG0640	Transcriptional regulator
LIS80_RS27835	COG0640	Transcriptional regulator
LIS80_RS27840	COG0798	PFAM Bile acid sodium symporter
LIS80_RS27880	COG4974	Belongs to the 'phage' integrase family
LIS80_RS27895	COG0457	Tetratricopeptide repeat
LIS80_RS28015	COG3344	reverse transcriptase
LIS80_RS28035	COG3344	reverse transcriptase
LIS80_RS28085	COG1396	sequence-specific DNA binding
LIS80_RS28110	COG3397	chitin binding
LIS80_RS28145	COG0791	NLP P60 protein
LIS80_RS28145	COG1388	LysM domain
LIS80_RS28145	COG3103	Sh3 type 3 domain protein
LIS80_RS28190	COG0640	Transcriptional regulator
LIS80_RS28350	COG4712	double-strand break repair protein