locus-tag	class	description
PGS39_RS00010	COG0592	DNA-directed DNA polymerase activity
PGS39_RS00015	COG2501	S4 domain
PGS39_RS00025	COG0187	DNA topoisomerase II activity
PGS39_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGS39_RS00065	COG0516	GMP reductase activity
PGS39_RS00065	COG0517	IMP dehydrogenase activity
PGS39_RS00070	COG1686	Belongs to the peptidase S11 family
PGS39_RS00100	COG1428	Deoxynucleoside kinase
PGS39_RS00105	COG1428	Deoxynucleoside kinase
PGS39_RS00110	COG1335	isochorismatase
PGS39_RS00115	COG0590	tRNA wobble adenosine to inosine editing
PGS39_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGS39_RS00180	COG1982	Orn Lys Arg decarboxylase major
PGS39_RS00190	COG0470	DNA polymerase III
PGS39_RS00195	COG1774	PSP1 C-terminal conserved region
PGS39_RS00205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PGS39_RS00215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGS39_RS00220	COG2002	toxin-antitoxin pair type II binding
PGS39_RS00225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGS39_RS00225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGS39_RS00230	COG0084	hydrolase, TatD family'
PGS39_RS00235	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGS39_RS00250	COG4466	Protein conserved in bacteria
PGS39_RS00265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGS39_RS00270	COG0251	oxidation-reduction process
PGS39_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGS39_RS00305	COG2002	toxin-antitoxin pair type II binding
PGS39_RS00310	COG2244	polysaccharide biosynthetic process
PGS39_RS00315	COG3956	TIGRFAM MazG family protein
PGS39_RS00320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PGS39_RS00340	COG1098	S1 RNA binding domain
PGS39_RS00355	COG2208	phosphoserine phosphatase activity
PGS39_RS00365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PGS39_RS00370	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGS39_RS00385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PGS39_RS00390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGS39_RS00395	COG0512	Glutamine amidotransferase of anthranilate synthase
PGS39_RS00400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PGS39_RS00405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGS39_RS00410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGS39_RS00415	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGS39_RS00420	COG1396	sequence-specific DNA binding
PGS39_RS00425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGS39_RS00515	COG3880	PFAM UvrB UvrC protein
PGS39_RS00525	COG0542	response to heat
PGS39_RS00530	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGS39_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
PGS39_RS00560	COG1045	serine acetyltransferase
PGS39_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGS39_RS00580	COG3688	RNA-binding protein containing a PIN domain
PGS39_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PGS39_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
PGS39_RS00605	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGS39_RS00625	COG2813	Specifically methylates the guanine in position
PGS39_RS00640	COG1358	cellular component organization or biogenesis
PGS39_RS00710	COG0255	Belongs to the universal ribosomal protein uL29 family
PGS39_RS00770	COG0201	protein transport
PGS39_RS00780	COG0024	Methionine aminopeptidase
PGS39_RS00790	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PGS39_RS00795	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGS39_RS00825	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGS39_RS00850	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS00855	COG0489	protein tyrosine kinase activity
PGS39_RS00865	COG2194	sulfuric ester hydrolase activity
PGS39_RS00870	COG0726	polysaccharide deacetylase
PGS39_RS00950	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGS39_RS00955	COG4856	YbbR-like protein
PGS39_RS00975	COG0596	Alpha beta hydrolase
PGS39_RS00995	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGS39_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS01035	COG2011	ABC-type metal ion transport system permease component
PGS39_RS01045	COG1464	Belongs to the NlpA lipoprotein family
PGS39_RS01050	COG0604	alcohol dehydrogenase
PGS39_RS01060	COG0277	FAD linked oxidase domain protein
PGS39_RS01065	COG2271	Major facilitator Superfamily
PGS39_RS01075	COG2814	Major facilitator Superfamily
PGS39_RS01090	COG0601	transmembrane transport
PGS39_RS01095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGS39_RS01100	COG0444	Belongs to the ABC transporter superfamily
PGS39_RS01105	COG4608	Belongs to the ABC transporter superfamily
PGS39_RS01110	COG4166	transmembrane transport
PGS39_RS01125	COG4166	transmembrane transport
PGS39_RS01130	COG4166	transmembrane transport
PGS39_RS01135	COG0656	L-ascorbic acid biosynthetic process
PGS39_RS01155	COG4149	molybdate abc transporter
PGS39_RS01160	COG0725	ABC transporter, periplasmic molybdate-binding protein
PGS39_RS01165	COG1910	domain protein
PGS39_RS01180	COG0697	spore germination
PGS39_RS01195	COG0204	Acyl-transferase
PGS39_RS01205	COG1609	Transcriptional regulator
PGS39_RS01215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS01225	COG0084	hydrolase, TatD family'
PGS39_RS01230	COG5298	Protein conserved in bacteria
PGS39_RS01255	COG0488	(ABC) transporter
PGS39_RS01265	COG0747	negative chemotaxis
PGS39_RS01270	COG0747	negative chemotaxis
PGS39_RS01275	COG0601	transmembrane transport
PGS39_RS01280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGS39_RS01285	COG0444	Belongs to the ABC transporter superfamily
PGS39_RS01290	COG4608	Belongs to the ABC transporter superfamily
PGS39_RS01295	COG0561	phosphatase activity
PGS39_RS01325	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PGS39_RS01330	COG0179	Fumarylacetoacetate (FAA) hydrolase
PGS39_RS01340	COG0531	amino acid
PGS39_RS01345	COG2814	Major facilitator Superfamily
PGS39_RS01355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PGS39_RS01365	COG4294	response to UV
PGS39_RS01370	COG0705	Rhomboid family
PGS39_RS01380	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PGS39_RS01385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGS39_RS01390	COG0864	Transcriptional regulator
PGS39_RS01395	COG2337	Toxic component of a toxin-antitoxin (TA) module
PGS39_RS01400	COG2183	response to ionizing radiation
PGS39_RS01495	COG0802	atpase or kinase
PGS39_RS01500	COG1214	PFAM Peptidase M22, glycoprotease
PGS39_RS01505	COG0456	acetyltransferase
PGS39_RS01515	COG0488	(ABC) transporter
PGS39_RS01530	COG1266	CAAX protease self-immunity
PGS39_RS01550	COG2252	PERMEase
PGS39_RS01560	COG5002	protein histidine kinase activity
PGS39_RS01585	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PGS39_RS01615	COG2226	methyltransferase
PGS39_RS01635	COG1215	transferase activity, transferring glycosyl groups
PGS39_RS01655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS01660	COG0506	proline dehydrogenase activity
PGS39_RS01685	COG0697	spore germination
PGS39_RS01715	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGS39_RS01720	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGS39_RS01725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGS39_RS01735	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGS39_RS01750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGS39_RS01760	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGS39_RS01770	COG0151	Belongs to the GarS family
PGS39_RS01795	COG0210	DNA helicase
PGS39_RS01805	COG4851	CamS sex pheromone cAM373 precursor
PGS39_RS01825	COG1335	isochorismatase
PGS39_RS01835	COG2011	ABC-type metal ion transport system permease component
PGS39_RS01855	COG0003	Pfam Anion-transporting ATPase
PGS39_RS01860	COG1846	Transcriptional regulator
PGS39_RS01865	COG4682	membrane
PGS39_RS01885	COG1597	lipid kinase activity
PGS39_RS01890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PGS39_RS01895	COG0546	phosphoglycolate phosphatase activity
PGS39_RS01900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGS39_RS01910	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS01915	COG2076	Multidrug Resistance protein
PGS39_RS01920	COG2309	aminopeptidase activity
PGS39_RS01930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS01940	COG0582	viral genome integration into host DNA
PGS39_RS01955	COG1396	sequence-specific DNA binding
PGS39_RS01975	COG1396	sequence-specific DNA binding
PGS39_RS02000	COG1484	DNA-dependent DNA replication
PGS39_RS02075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PGS39_RS02080	COG0582	viral genome integration into host DNA
PGS39_RS02115	COG1802	Transcriptional regulator
PGS39_RS02115	COG4626	Terminase
PGS39_RS02125	COG0740	serine-type endopeptidase activity
PGS39_RS02250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGS39_RS02260	COG0028	Belongs to the TPP enzyme family
PGS39_RS02270	COG4807	Protein conserved in bacteria
PGS39_RS02295	COG0673	inositol 2-dehydrogenase activity
PGS39_RS02300	COG0277	FAD linked oxidase domain protein
PGS39_RS02310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PGS39_RS02330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGS39_RS02335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PGS39_RS02345	COG2814	Major facilitator Superfamily
PGS39_RS02355	COG4807	Protein conserved in bacteria
PGS39_RS02380	COG1757	Na H antiporter
PGS39_RS02385	COG1473	amidohydrolase
PGS39_RS02400	COG0450	alkyl hydroperoxide reductase
PGS39_RS02430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS02435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS02440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS02455	COG0166	Belongs to the GPI family
PGS39_RS02495	COG3541	Predicted nucleotidyltransferase
PGS39_RS02500	COG2814	Major facilitator Superfamily
PGS39_RS02505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGS39_RS02505	COG0723	plastoquinol--plastocyanin reductase activity
PGS39_RS02530	COG0765	amino acid transport
PGS39_RS02535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS02545	COG0840	transmembrane signaling receptor activity
PGS39_RS02550	COG0366	Alpha amylase catalytic
PGS39_RS02555	COG2190	(PTS) system
PGS39_RS02555	COG1263	PTS System
PGS39_RS02555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS02575	COG1695	Transcriptional regulator
PGS39_RS02585	COG0577	efflux transmembrane transporter activity
PGS39_RS02590	COG1136	(ABC) transporter
PGS39_RS02615	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PGS39_RS02645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
PGS39_RS02660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGS39_RS02670	COG1116	anion transmembrane transporter activity
PGS39_RS02680	COG0488	(ABC) transporter
PGS39_RS02730	COG2270	Major facilitator Superfamily
PGS39_RS02760	COG2310	stress, protein
PGS39_RS02765	COG2310	stress, protein
PGS39_RS02770	COG2310	stress, protein
PGS39_RS02775	COG0861	Integral membrane protein TerC family
PGS39_RS02785	COG3853	Toxic anion resistance protein (TelA)
PGS39_RS02800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGS39_RS02810	COG1295	ribonuclease BN
PGS39_RS02815	COG2217	Heavy metal translocating P-type atpase
PGS39_RS02820	COG0697	spore germination
PGS39_RS02835	COG0681	Belongs to the peptidase S26 family
PGS39_RS02845	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS02860	COG3871	stress protein (general stress protein 26)
PGS39_RS02865	COG0387	Pfam Sodium calcium exchanger
PGS39_RS02875	COG0535	radical SAM domain protein
PGS39_RS02895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PGS39_RS02915	COG3829	transcription factor binding
PGS39_RS02925	COG0833	amino acid
PGS39_RS02930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PGS39_RS02965	COG1263	PTS System
PGS39_RS02965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS02970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PGS39_RS02985	COG0463	Glycosyl transferase, family 2
PGS39_RS02995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PGS39_RS02995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGS39_RS03010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGS39_RS03030	COG0402	S-adenosylhomocysteine deaminase activity
PGS39_RS03035	COG1090	epimerase
PGS39_RS03065	COG1988	membrane-bound metal-dependent
PGS39_RS03070	COG1194	a g-specific adenine glycosylase
PGS39_RS03095	COG1132	(ABC) transporter
PGS39_RS03100	COG4129	membrane
PGS39_RS03105	COG0070	glutamate synthase
PGS39_RS03105	COG0069	glutamate synthase activity
PGS39_RS03105	COG0067	glutamate synthase
PGS39_RS03115	COG4555	ABC transporter
PGS39_RS03135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PGS39_RS03140	COG0735	belongs to the Fur family
PGS39_RS03240	COG4974	Belongs to the 'phage' integrase family
PGS39_RS03290	COG3646	Phage regulatory protein
PGS39_RS03295	COG3646	Phage regulatory protein
PGS39_RS03315	COG0457	Tetratricopeptide repeat
PGS39_RS03345	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PGS39_RS03365	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGS39_RS03375	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PGS39_RS03385	COG2766	serine protein kinase
PGS39_RS03405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PGS39_RS03415	COG1585	Membrane protein implicated in regulation of membrane protease activity
PGS39_RS03420	COG2268	Band 7 protein
PGS39_RS03430	COG3290	protein histidine kinase activity
PGS39_RS03435	COG4565	transcriptional regulatory protein
PGS39_RS03440	COG2851	Citrate transporter
PGS39_RS03465	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PGS39_RS03470	COG3842	ATPase activity
PGS39_RS03475	COG1175	transmembrane transport
PGS39_RS03480	COG0395	ABC-type sugar transport system, permease component
PGS39_RS03490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PGS39_RS03495	COG0745	RESPONSE REGULATOR receiver
PGS39_RS03500	COG5002	protein histidine kinase activity
PGS39_RS03510	COG4990	cell redox homeostasis
PGS39_RS03520	COG0697	spore germination
PGS39_RS03525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS03535	COG5002	protein histidine kinase activity
PGS39_RS03540	COG0745	RESPONSE REGULATOR receiver
PGS39_RS03550	COG0454	-acetyltransferase
PGS39_RS03550	COG0456	acetyltransferase
PGS39_RS03555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PGS39_RS03560	COG3383	formate dehydrogenase (NAD+) activity
PGS39_RS03565	COG2427	Protein of unknown function (DUF1641)
PGS39_RS03580	COG0531	amino acid
PGS39_RS03585	COG0640	Transcriptional regulator
PGS39_RS03590	COG2217	Heavy metal translocating P-type atpase
PGS39_RS03595	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGS39_RS03610	COG3227	Zinc metalloprotease (Elastase)
PGS39_RS03630	COG2720	vancomycin resistance protein
PGS39_RS03635	COG1316	TRANSCRIPTIONal
PGS39_RS03640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS03645	COG0346	lactoylglutathione lyase activity
PGS39_RS03650	COG1253	flavin adenine dinucleotide binding
PGS39_RS03655	COG1027	Aspartate ammonia-lyase
PGS39_RS03665	COG1620	l-lactate permease
PGS39_RS03680	COG3104	oligopeptide transport
PGS39_RS03685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS03690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS03705	COG2226	methyltransferase
PGS39_RS03710	COG0156	8-amino-7-oxononanoate synthase activity
PGS39_RS03715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PGS39_RS03720	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGS39_RS03730	COG4548	von Willebrand factor, type A
PGS39_RS03735	COG0714	Associated with various cellular activities
PGS39_RS03740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS03760	COG0531	amino acid
PGS39_RS03765	COG2188	Transcriptional regulator
PGS39_RS03770	COG1263	PTS System
PGS39_RS03770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS03775	COG0366	Alpha amylase catalytic
PGS39_RS03790	COG0697	spore germination
PGS39_RS03795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PGS39_RS03800	COG1115	amino acid carrier protein
PGS39_RS03805	COG1126	abc transporter atp-binding protein
PGS39_RS03810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS03815	COG0765	amino acid transport
PGS39_RS03820	COG0765	amino acid transport
PGS39_RS03825	COG0833	amino acid
PGS39_RS03840	COG1595	DNA-templated transcription, initiation
PGS39_RS03850	COG2378	regulation of single-species biofilm formation
PGS39_RS03855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGS39_RS03860	COG5002	protein histidine kinase activity
PGS39_RS03875	COG0659	secondary active sulfate transmembrane transporter activity
PGS39_RS03890	COG0747	negative chemotaxis
PGS39_RS03900	COG0601	transmembrane transport
PGS39_RS03905	COG4608	Belongs to the ABC transporter superfamily
PGS39_RS03915	COG2271	Major facilitator Superfamily
PGS39_RS03920	COG1846	Transcriptional regulator
PGS39_RS03925	COG0477	Major facilitator Superfamily
PGS39_RS03930	COG1609	Transcriptional regulator
PGS39_RS03935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGS39_RS03950	COG1172	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS03955	COG1879	ABC-type sugar transport system periplasmic component
PGS39_RS03975	COG1063	alcohol dehydrogenase
PGS39_RS03990	COG3568	Endonuclease Exonuclease Phosphatase
PGS39_RS04020	COG0840	transmembrane signaling receptor activity
PGS39_RS04025	COG3583	domain protein
PGS39_RS04025	COG3584	3D domain protein
PGS39_RS04030	COG1476	TRANSCRIPTIONal
PGS39_RS04050	COG3104	oligopeptide transport
PGS39_RS04055	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS04070	COG1113	amino acid transport
PGS39_RS04075	COG2252	PERMEase
PGS39_RS04090	COG2153	protein acetylation
PGS39_RS04100	COG0569	domain protein
PGS39_RS04100	COG0475	glutathione-regulated potassium exporter activity
PGS39_RS04115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGS39_RS04120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PGS39_RS04130	COG4990	cell redox homeostasis
PGS39_RS04145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGS39_RS04150	COG0697	spore germination
PGS39_RS04155	COG0531	amino acid
PGS39_RS04165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PGS39_RS04170	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PGS39_RS04175	COG1918	ferrous iron import across plasma membrane
PGS39_RS04175	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
PGS39_RS04180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PGS39_RS04185	COG0573	inorganic phosphate transmembrane transporter activity
PGS39_RS04190	COG0581	inorganic phosphate transmembrane transporter activity
PGS39_RS04195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGS39_RS04315	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
PGS39_RS04335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGS39_RS04340	COG1116	anion transmembrane transporter activity
PGS39_RS04345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGS39_RS04350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PGS39_RS04355	COG0352	thiamine-phosphate diphosphorylase activity
PGS39_RS04360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGS39_RS04365	COG2104	thiamine diphosphate biosynthetic process
PGS39_RS04375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGS39_RS04380	COG0351	phosphomethylpyrimidine kinase
PGS39_RS04420	COG2205	protein histidine kinase activity
PGS39_RS04425	COG2814	Major facilitator Superfamily
PGS39_RS04430	COG1846	Transcriptional regulator
PGS39_RS04455	COG1136	(ABC) transporter
PGS39_RS04470	COG1172	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS04475	COG1129	ABC transporter
PGS39_RS04485	COG2252	PERMEase
PGS39_RS04490	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS04505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGS39_RS04510	COG1621	beta-fructofuranosidase activity
PGS39_RS04515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS04515	COG1263	PTS System
PGS39_RS04520	COG1609	Transcriptional regulator
PGS39_RS04530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS04570	COG0778	Nitroreductase
PGS39_RS04575	COG2719	SpoVR family
PGS39_RS04585	COG0433	COG0433 Predicted ATPase
PGS39_RS04605	COG0446	pyridine nucleotide-disulphide oxidoreductase
PGS39_RS04610	COG1937	Protein conserved in bacteria
PGS39_RS04615	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGS39_RS04615	COG0425	Belongs to the sulfur carrier protein TusA family
PGS39_RS04620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS04620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGS39_RS04625	COG0425	Belongs to the sulfur carrier protein TusA family
PGS39_RS04630	COG0425	Belongs to the sulfur carrier protein TusA family
PGS39_RS04635	COG0425	Belongs to the sulfur carrier protein TusA family
PGS39_RS04635	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGS39_RS04645	COG2210	Belongs to the sulfur carrier protein TusA family
PGS39_RS04650	COG0730	response to heat
PGS39_RS04660	COG1316	TRANSCRIPTIONal
PGS39_RS04665	COG0604	alcohol dehydrogenase
PGS39_RS04670	COG1283	sodium-dependent phosphate transmembrane transporter activity
PGS39_RS04675	COG2814	Major facilitator Superfamily
PGS39_RS04685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PGS39_RS04685	COG3711	transcriptional antiterminator
PGS39_RS04690	COG1447	Phosphotransferase system cellobiose-specific component IIA
PGS39_RS04695	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PGS39_RS04720	COG3584	3D domain protein
PGS39_RS04720	COG1388	LysM domain
PGS39_RS04725	COG0577	efflux transmembrane transporter activity
PGS39_RS04730	COG1136	(ABC) transporter
PGS39_RS04740	COG5522	Integral membrane protein (intg_mem_TP0381)
PGS39_RS04755	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS04760	COG3546	catalase activity
PGS39_RS04795	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS04830	COG0531	amino acid
PGS39_RS04835	COG0475	glutathione-regulated potassium exporter activity
PGS39_RS04845	COG1737	Transcriptional regulator
PGS39_RS04855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS04855	COG1263	PTS System
PGS39_RS04865	COG2259	Doxx family
PGS39_RS04885	COG1522	sequence-specific DNA binding
PGS39_RS04900	COG2076	Multidrug Resistance protein
PGS39_RS04905	COG1309	transcriptional regulator
PGS39_RS04910	COG2814	Major facilitator Superfamily
PGS39_RS04915	COG1733	regulation of RNA biosynthetic process
PGS39_RS04920	COG1846	Transcriptional regulator
PGS39_RS04925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PGS39_RS04930	COG0477	Major facilitator Superfamily
PGS39_RS04935	COG0657	acetylesterase activity
PGS39_RS04940	COG0657	acetylesterase activity
PGS39_RS04955	COG2124	cytochrome p450
PGS39_RS04965	COG1063	alcohol dehydrogenase
PGS39_RS04975	COG1309	transcriptional regulator
PGS39_RS04980	COG1683	Conserved Protein
PGS39_RS05000	COG3344	reverse transcriptase
PGS39_RS05015	COG1733	regulation of RNA biosynthetic process
PGS39_RS05025	COG2249	NAD(P)H dehydrogenase (quinone) activity
PGS39_RS05030	COG4533	DNA binding
PGS39_RS05035	COG2211	Major facilitator Superfamily
PGS39_RS05045	COG0693	protein deglycase activity
PGS39_RS05055	COG0531	amino acid
PGS39_RS05060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PGS39_RS05065	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS05070	COG1132	(ABC) transporter
PGS39_RS05075	COG1132	(ABC) transporter
PGS39_RS05080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS05085	COG0765	amino acid transport
PGS39_RS05090	COG1126	abc transporter atp-binding protein
PGS39_RS05105	COG0189	ligase activity
PGS39_RS05135	COG0028	Belongs to the TPP enzyme family
PGS39_RS05140	COG3527	Alpha-acetolactate decarboxylase
PGS39_RS05150	COG0561	phosphatase activity
PGS39_RS05155	COG3409	Peptidoglycan-binding domain 1 protein
PGS39_RS05155	COG5632	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS05160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PGS39_RS05180	COG0659	secondary active sulfate transmembrane transporter activity
PGS39_RS05195	COG0653	protein targeting
PGS39_RS05200	COG2244	polysaccharide biosynthetic process
PGS39_RS05210	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS05215	COG4196	transglutaminase domain protein
PGS39_RS05230	COG1696	Membrane protein involved in D-alanine export
PGS39_RS05245	COG1024	Enoyl-CoA hydratase
PGS39_RS05280	COG1363	Peptidase, m42
PGS39_RS05335	COG0477	Major facilitator Superfamily
PGS39_RS05340	COG3290	protein histidine kinase activity
PGS39_RS05345	COG4565	transcriptional regulatory protein
PGS39_RS05350	COG3181	Tripartite tricarboxylate transporter family receptor
PGS39_RS05410	COG0582	viral genome integration into host DNA
PGS39_RS05425	COG0789	Transcriptional regulator
PGS39_RS05425	COG4978	Transcriptional regulator
PGS39_RS05440	COG0305	Participates in initiation and elongation during chromosome replication
PGS39_RS05465	COG0477	Major facilitator Superfamily
PGS39_RS05535	COG1183	phosphatidylcholine synthase activity
PGS39_RS05550	COG2376	Dihydroxyacetone kinase
PGS39_RS05560	COG2376	Dihydroxyacetone kinase
PGS39_RS05590	COG3437	response regulator, receiver
PGS39_RS05590	COG2770	Histidine kinase
PGS39_RS05675	COG3237	CsbD-like
PGS39_RS05700	COG1191	sigma factor activity
PGS39_RS05710	COG2208	phosphoserine phosphatase activity
PGS39_RS05715	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PGS39_RS05720	COG0784	Response regulator, receiver
PGS39_RS05720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS05720	COG2198	Histidine kinase
PGS39_RS05720	COG2205	protein histidine kinase activity
PGS39_RS05790	COG0420	3'-5' exonuclease activity
PGS39_RS05795	COG4717	serine-type aminopeptidase activity
PGS39_RS05805	COG1309	transcriptional regulator
PGS39_RS05810	COG2814	Major facilitator Superfamily
PGS39_RS05815	COG0346	lactoylglutathione lyase activity
PGS39_RS05820	COG0346	lactoylglutathione lyase activity
PGS39_RS05830	COG2267	carboxylic ester hydrolase activity
PGS39_RS05865	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PGS39_RS05870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PGS39_RS05880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PGS39_RS05900	COG1595	DNA-templated transcription, initiation
PGS39_RS05910	COG0772	Belongs to the SEDS family
PGS39_RS05920	COG3973	AAA domain
PGS39_RS05925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGS39_RS05945	COG4980	gas vesicle protein
PGS39_RS05950	COG0537	adenosine 5'-monophosphoramidase activity
PGS39_RS05955	COG1131	(ABC) transporter
PGS39_RS05960	COG4473	ABC transporter
PGS39_RS05975	COG1309	transcriptional regulator
PGS39_RS05985	COG3402	PFAM membrane-flanked domain
PGS39_RS05990	COG3428	Bacterial PH domain
PGS39_RS06020	COG3402	PFAM membrane-flanked domain
PGS39_RS06025	COG3428	Bacterial PH domain
PGS39_RS06030	COG2329	Antibiotic biosynthesis monooxygenase
PGS39_RS06035	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGS39_RS06050	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PGS39_RS06080	COG1309	transcriptional regulator
PGS39_RS06085	COG1511	domain protein
PGS39_RS06115	COG2378	regulation of single-species biofilm formation
PGS39_RS06120	COG1609	Transcriptional regulator
PGS39_RS06130	COG1234	tRNA 3'-trailer cleavage
PGS39_RS06135	COG0095	Lipoate-protein ligase
PGS39_RS06145	COG0318	PFAM AMP-dependent synthetase and ligase
PGS39_RS06220	COG1073	alpha beta
PGS39_RS06225	COG1408	metallophosphoesterase
PGS39_RS06235	COG1078	dGTPase activity
PGS39_RS06245	COG1595	DNA-templated transcription, initiation
PGS39_RS06250	COG2207	Transcriptional regulator
PGS39_RS06250	COG3708	Transcriptional regulator
PGS39_RS06265	COG2205	protein histidine kinase activity
PGS39_RS06270	COG0745	RESPONSE REGULATOR receiver
PGS39_RS06295	COG0501	Belongs to the peptidase M48B family
PGS39_RS06300	COG0697	spore germination
PGS39_RS06320	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PGS39_RS06325	COG2224	Isocitrate lyase
PGS39_RS06335	COG1278	Cold shock
PGS39_RS06350	COG4903	ComK protein
PGS39_RS06360	COG0398	Pfam SNARE associated Golgi protein
PGS39_RS06420	COG0179	Fumarylacetoacetate (FAA) hydrolase
PGS39_RS06445	COG0367	asparagine synthase
PGS39_RS06455	COG0753	catalase activity
PGS39_RS06460	COG0004	ammonium transporteR
PGS39_RS06480	COG2996	Protein conserved in bacteria
PGS39_RS06485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGS39_RS06495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS06510	COG0561	phosphatase activity
PGS39_RS06530	COG2267	carboxylic ester hydrolase activity
PGS39_RS06545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGS39_RS06550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PGS39_RS06555	COG5504	Zn-dependent protease
PGS39_RS06565	COG0180	Tryptophanyl-tRNA synthetase
PGS39_RS06575	COG4166	transmembrane transport
PGS39_RS06580	COG0601	transmembrane transport
PGS39_RS06585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGS39_RS06590	COG0444	Belongs to the ABC transporter superfamily
PGS39_RS06595	COG4608	Belongs to the ABC transporter superfamily
PGS39_RS06600	COG0534	Mate efflux family protein
PGS39_RS06605	COG4166	transmembrane transport
PGS39_RS06620	COG0861	Integral membrane protein TerC family
PGS39_RS06625	COG4862	establishment of competence for transformation
PGS39_RS06630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS06640	COG1164	Oligoendopeptidase f
PGS39_RS06655	COG2346	COG2346, Truncated hemoglobins
PGS39_RS06660	COG4116	CYTH
PGS39_RS06670	COG2357	RelA SpoT domain protein
PGS39_RS06680	COG0564	pseudouridine synthase activity
PGS39_RS06695	COG0772	Belongs to the SEDS family
PGS39_RS06700	COG0463	Glycosyl transferase, family 2
PGS39_RS06700	COG1216	Glycosyl transferase, family 2
PGS39_RS06720	COG0463	Glycosyl transferase, family 2
PGS39_RS06720	COG0457	Tetratricopeptide repeat
PGS39_RS06740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PGS39_RS06755	COG1091	dTDP-4-dehydrorhamnose reductase activity
PGS39_RS06800	COG2153	protein acetylation
PGS39_RS06810	COG2382	esterase
PGS39_RS06825	COG5492	domain, Protein
PGS39_RS06830	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGS39_RS06840	COG0512	Glutamine amidotransferase of anthranilate synthase
PGS39_RS06840	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGS39_RS06875	COG1620	l-lactate permease
PGS39_RS06880	COG5634	Uncharacterized conserved protein (DUF2278)
PGS39_RS06885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS06955	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGS39_RS06965	COG1476	TRANSCRIPTIONal
PGS39_RS07035	COG2003	Belongs to the UPF0758 family
PGS39_RS07055	COG0582	viral genome integration into host DNA
PGS39_RS07060	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PGS39_RS07070	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PGS39_RS07095	COG1686	Belongs to the peptidase S11 family
PGS39_RS07100	COG0681	Belongs to the peptidase S26 family
PGS39_RS07135	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS07145	COG1176	ABC-type spermidine putrescine transport system, permease component I
PGS39_RS07150	COG1177	transmembrane transport
PGS39_RS07155	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PGS39_RS07165	COG2409	Drug exporters of the RND superfamily
PGS39_RS07175	COG0564	pseudouridine synthase activity
PGS39_RS07185	COG2340	Cysteine-rich secretory protein family
PGS39_RS07190	COG0247	lactate metabolic process
PGS39_RS07195	COG0277	FAD linked oxidase domain protein
PGS39_RS07200	COG3835	regulator
PGS39_RS07210	COG0745	RESPONSE REGULATOR receiver
PGS39_RS07215	COG5002	protein histidine kinase activity
PGS39_RS07220	COG2186	Transcriptional regulator
PGS39_RS07240	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PGS39_RS07250	COG2116	formate transmembrane transporter activity
PGS39_RS07255	COG0861	Integral membrane protein TerC family
PGS39_RS07260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PGS39_RS07270	COG2030	dehydratase
PGS39_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS07295	COG3243	poly(R)-hydroxyalkanoic acid synthase
PGS39_RS07305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PGS39_RS07320	COG1840	ABC-type Fe3 transport system, periplasmic component
PGS39_RS07325	COG3842	ATPase activity
PGS39_RS07350	COG1349	DNA-binding transcription factor activity
PGS39_RS07360	COG0235	Class ii aldolase
PGS39_RS07370	COG2861	carbohydrate metabolic process
PGS39_RS07380	COG3852	Histidine kinase
PGS39_RS07385	COG1846	Transcriptional regulator
PGS39_RS07395	COG2318	DinB family
PGS39_RS07405	COG5002	protein histidine kinase activity
PGS39_RS07415	COG0720	synthase
PGS39_RS07430	COG4873	Protein conserved in bacteria
PGS39_RS07460	COG1780	Probably involved in ribonucleotide reductase function
PGS39_RS07485	COG1725	Transcriptional regulator
PGS39_RS07490	COG1131	(ABC) transporter
PGS39_RS07500	COG1131	(ABC) transporter
PGS39_RS07505	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PGS39_RS07510	COG1266	CAAX protease self-immunity
PGS39_RS07520	COG1522	sequence-specific DNA binding
PGS39_RS07530	COG1335	isochorismatase
PGS39_RS07540	COG1619	proteins homologs of microcin C7 resistance protein MccF
PGS39_RS07545	COG2070	2-Nitropropane dioxygenase
PGS39_RS07550	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGS39_RS07560	COG1696	Membrane protein involved in D-alanine export
PGS39_RS07585	COG0716	FMN binding
PGS39_RS07600	COG3173	Aminoglycoside phosphotransferase
PGS39_RS07620	COG0534	Mate efflux family protein
PGS39_RS07640	COG1846	Transcriptional regulator
PGS39_RS07650	COG1301	dicarboxylic acid transport
PGS39_RS07655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PGS39_RS07660	COG4709	membrane
PGS39_RS07665	COG3874	Sporulation protein YtfJ
PGS39_RS07685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PGS39_RS07690	COG0028	Belongs to the TPP enzyme family
PGS39_RS07695	COG0440	acetolactate synthase activity
PGS39_RS07770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PGS39_RS07785	COG1183	phosphatidylcholine synthase activity
PGS39_RS07790	COG1368	sulfuric ester hydrolase activity
PGS39_RS07800	COG0019	diaminopimelate decarboxylase activity
PGS39_RS07820	COG0529	Catalyzes the synthesis of activated sulfate
PGS39_RS07825	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PGS39_RS07845	COG1648	precorrin-2 dehydrogenase activity
PGS39_RS07850	COG0733	neurotransmitter:sodium symporter activity
PGS39_RS07875	COG1757	Na H antiporter
PGS39_RS07890	COG4758	membrane
PGS39_RS07895	COG4585	Histidine kinase
PGS39_RS07900	COG2197	response regulator
PGS39_RS07910	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS07920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PGS39_RS07960	COG0730	response to heat
PGS39_RS07965	COG0306	phosphate transporter
PGS39_RS07970	COG1392	Phosphate transport regulator
PGS39_RS07975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGS39_RS07990	COG3852	Histidine kinase
PGS39_RS07995	COG1801	Protein of unknown function DUF72
PGS39_RS08005	COG0582	viral genome integration into host DNA
PGS39_RS08010	COG5002	protein histidine kinase activity
PGS39_RS08025	COG0392	lysyltransferase activity
PGS39_RS08025	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGS39_RS08040	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PGS39_RS08045	COG1686	Belongs to the peptidase S11 family
PGS39_RS08050	COG2715	membrane protein required for spore maturation
PGS39_RS08055	COG0700	Nucleoside recognition
PGS39_RS08060	COG1187	pseudouridine synthase activity
PGS39_RS08070	COG1333	cytochrome c biogenesis protein
PGS39_RS08075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PGS39_RS08080	COG0745	RESPONSE REGULATOR receiver
PGS39_RS08085	COG5002	protein histidine kinase activity
PGS39_RS08090	COG2096	Adenosyltransferase
PGS39_RS08095	COG4942	peptidase
PGS39_RS08105	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGS39_RS08110	COG1141	Ferredoxin
PGS39_RS08120	COG0514	ATP-dependent DNA helicase (RecQ)
PGS39_RS08125	COG1266	CAAX protease self-immunity
PGS39_RS08135	COG1408	metallophosphoesterase
PGS39_RS08145	COG4862	establishment of competence for transformation
PGS39_RS08150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PGS39_RS08170	COG0492	ferredoxin-NADP+ reductase activity
PGS39_RS08245	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGS39_RS08260	COG0142	geranyltranstransferase activity
PGS39_RS08270	COG0142	geranyltranstransferase activity
PGS39_RS08290	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGS39_RS08300	COG0457	Tetratricopeptide repeat
PGS39_RS08320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PGS39_RS08325	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PGS39_RS08325	COG2010	Cytochrome c
PGS39_RS08335	COG4347	Protein of unknown function (DUF1405)
PGS39_RS08350	COG2738	Putative neutral zinc metallopeptidase
PGS39_RS08360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS08365	COG1694	Mazg nucleotide pyrophosphohydrolase
PGS39_RS08380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PGS39_RS08385	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS08420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PGS39_RS08420	COG1199	ATP-dependent helicase activity
PGS39_RS08440	COG3935	DnaD domain protein
PGS39_RS08445	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGS39_RS08455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGS39_RS08455	COG4499	WXG100 protein secretion system (Wss), protein YukC
PGS39_RS08515	COG0116	Belongs to the methyltransferase superfamily
PGS39_RS08525	COG1199	ATP-dependent helicase activity
PGS39_RS08530	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PGS39_RS08540	COG0024	Methionine aminopeptidase
PGS39_RS08550	COG2233	PERMEase
PGS39_RS08555	COG2311	Membrane
PGS39_RS08565	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGS39_RS08575	COG0456	acetyltransferase
PGS39_RS08610	COG0754	glutathionylspermidine amidase activity
PGS39_RS08625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGS39_RS08675	COG0328	RNA-DNA hybrid ribonuclease activity
PGS39_RS08710	COG3403	YqcI/YcgG family
PGS39_RS08715	COG1280	lysine exporter protein (LysE YggA)
PGS39_RS08730	COG3162	membrane
PGS39_RS08735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGS39_RS08740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGS39_RS08750	COG0475	glutathione-regulated potassium exporter activity
PGS39_RS08755	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGS39_RS08760	COG4978	Transcriptional regulator
PGS39_RS08760	COG0789	Transcriptional regulator
PGS39_RS08775	COG2323	membrane
PGS39_RS08780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
PGS39_RS08815	COG2814	Major facilitator Superfamily
PGS39_RS08845	COG1923	regulation of RNA biosynthetic process
PGS39_RS08855	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PGS39_RS08860	COG1360	Flagellar Motor Protein
PGS39_RS08865	COG2201	protein-glutamate methylesterase activity
PGS39_RS08870	COG0643	Histidine kinase
PGS39_RS08870	COG2198	Histidine kinase
PGS39_RS08875	COG1776	CheC inhibitor of MCP methylation
PGS39_RS08875	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGS39_RS08890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PGS39_RS08910	COG1256	bacterial-type flagellum assembly
PGS39_RS08915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGS39_RS08920	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PGS39_RS08935	COG1815	bacterial-type flagellum-dependent cell motility
PGS39_RS08940	COG1558	bacterial-type flagellum-dependent cell motility
PGS39_RS08950	COG1766	The M ring may be actively involved in energy transduction
PGS39_RS08955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGS39_RS08965	COG1157	protein secretion by the type III secretion system
PGS39_RS09000	COG0835	chemotaxis
PGS39_RS09000	COG0784	Response regulator, receiver
PGS39_RS09010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGS39_RS09015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGS39_RS09020	COG0741	lytic transglycosylase activity
PGS39_RS09030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGS39_RS09035	COG1776	CheC inhibitor of MCP methylation
PGS39_RS09035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGS39_RS09045	COG1338	Plays a role in the flagellum-specific transport system
PGS39_RS09050	COG1987	bacterial-type flagellum assembly
PGS39_RS09060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGS39_RS09065	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGS39_RS09070	COG1419	protein localization to endoplasmic reticulum
PGS39_RS09075	COG4786	Flagellar basal body rod
PGS39_RS09080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGS39_RS09115	COG2329	Antibiotic biosynthesis monooxygenase
PGS39_RS09130	COG3764	Sortase (surface protein transpeptidase)
PGS39_RS09135	COG3764	Sortase (surface protein transpeptidase)
PGS39_RS09160	COG0583	DNA-binding transcription factor activity
PGS39_RS09165	COG3842	ATPase activity
PGS39_RS09180	COG1234	tRNA 3'-trailer cleavage
PGS39_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS09210	COG1686	Belongs to the peptidase S11 family
PGS39_RS09220	COG0406	alpha-ribazole phosphatase activity
PGS39_RS09240	COG1846	Transcriptional regulator
PGS39_RS09250	COG0367	asparagine synthase
PGS39_RS09255	COG3344	reverse transcriptase
PGS39_RS09290	COG1802	Transcriptional regulator
PGS39_RS09295	COG0697	spore germination
PGS39_RS09300	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS09300	COG1216	Glycosyl transferase, family 2
PGS39_RS09305	COG1757	Na H antiporter
PGS39_RS09315	COG0114	fumarate hydratase activity
PGS39_RS09340	COG0534	Mate efflux family protein
PGS39_RS09345	COG3340	Belongs to the peptidase S51 family
PGS39_RS09385	COG2733	membrane
PGS39_RS09420	COG1131	(ABC) transporter
PGS39_RS09435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS09440	COG0528	UMP kinase activity
PGS39_RS09450	COG1027	Aspartate ammonia-lyase
PGS39_RS09455	COG0281	malic enzyme
PGS39_RS09460	COG4191	Histidine kinase
PGS39_RS09465	COG0784	Response regulator, receiver
PGS39_RS09470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PGS39_RS09525	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS09535	COG2814	Major facilitator Superfamily
PGS39_RS09555	COG1966	Carbon starvation protein
PGS39_RS09565	COG1695	Transcriptional regulator
PGS39_RS09575	COG0477	Major facilitator Superfamily
PGS39_RS09580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGS39_RS09590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGS39_RS09600	COG2223	nitrite transmembrane transporter activity
PGS39_RS09605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PGS39_RS09620	COG2244	polysaccharide biosynthetic process
PGS39_RS09625	COG0733	neurotransmitter:sodium symporter activity
PGS39_RS09635	COG5566	PFAM Mor transcription activator
PGS39_RS09640	COG2323	membrane
PGS39_RS09655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGS39_RS09660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PGS39_RS09665	COG0028	Belongs to the TPP enzyme family
PGS39_RS09670	COG0440	acetolactate synthase activity
PGS39_RS09675	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGS39_RS09685	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGS39_RS09710	COG2814	Major facilitator Superfamily
PGS39_RS09715	COG3384	dioxygenase
PGS39_RS09725	COG3279	Response regulator of the LytR AlgR family
PGS39_RS09730	COG0427	acetyl-CoA hydrolase
PGS39_RS09750	COG1073	alpha beta
PGS39_RS09755	COG4166	transmembrane transport
PGS39_RS09760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS09765	COG0745	RESPONSE REGULATOR receiver
PGS39_RS09780	COG1914	H( )-stimulated, divalent metal cation uptake system
PGS39_RS09795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGS39_RS09805	COG0531	amino acid
PGS39_RS09825	COG0457	Tetratricopeptide repeat
PGS39_RS09835	COG2390	Transcriptional regulator
PGS39_RS09845	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS09850	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PGS39_RS09860	COG4846	Membrane protein involved in cytochrome C biogenesis
PGS39_RS09870	COG0006	proline dipeptidase activity
PGS39_RS09885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGS39_RS09905	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS09915	COG2372	response to copper ion
PGS39_RS09915	COG1276	copper resistance
PGS39_RS09920	COG4549	nuclear export factor GLE1
PGS39_RS09925	COG0697	spore germination
PGS39_RS09930	COG0583	DNA-binding transcription factor activity
PGS39_RS09935	COG1959	2 iron, 2 sulfur cluster binding
PGS39_RS09940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PGS39_RS09945	COG0778	Nitroreductase
PGS39_RS09960	COG0628	permease
PGS39_RS09970	COG1231	oxidoreductase activity
PGS39_RS09975	COG0523	cobalamin synthesis protein
PGS39_RS09985	COG0411	ABC transporter
PGS39_RS10005	COG0583	DNA-binding transcription factor activity
PGS39_RS10015	COG1942	4-Oxalocrotonate Tautomerase
PGS39_RS10035	COG1271	oxidase subunit
PGS39_RS10040	COG1294	oxidase, subunit
PGS39_RS10045	COG4988	ABC transporter
PGS39_RS10050	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PGS39_RS10060	COG1216	Glycosyl transferase, family 2
PGS39_RS10095	COG1619	proteins homologs of microcin C7 resistance protein MccF
PGS39_RS10100	COG1686	Belongs to the peptidase S11 family
PGS39_RS10115	COG1388	LysM domain
PGS39_RS10115	COG0791	NLP P60 protein
PGS39_RS10125	COG1132	(ABC) transporter
PGS39_RS10130	COG0745	RESPONSE REGULATOR receiver
PGS39_RS10135	COG5002	protein histidine kinase activity
PGS39_RS10145	COG0300	oxidoreductase activity
PGS39_RS10150	COG4122	O-methyltransferase activity
PGS39_RS10180	COG0460	homoserine dehydrogenase
PGS39_RS10205	COG1316	TRANSCRIPTIONal
PGS39_RS10225	COG1285	pathogenesis
PGS39_RS10230	COG1247	-acetyltransferase
PGS39_RS10240	COG2814	Major facilitator Superfamily
PGS39_RS10245	COG1279	arginine transmembrane transporter activity
PGS39_RS10250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS10260	COG1752	Esterase of the alpha-beta hydrolase superfamily
PGS39_RS10295	COG0577	efflux transmembrane transporter activity
PGS39_RS10300	COG2002	toxin-antitoxin pair type II binding
PGS39_RS10305	COG1404	Belongs to the peptidase S8 family
PGS39_RS10310	COG3842	ATPase activity
PGS39_RS10315	COG2508	Transcriptional regulator
PGS39_RS10330	COG1175	transmembrane transport
PGS39_RS10340	COG0395	ABC-type sugar transport system, permease component
PGS39_RS10345	COG5426	von Willebrand factor, type A
PGS39_RS10355	COG1940	carbohydrate kinase activity
PGS39_RS10360	COG2222	sugar isomerase
PGS39_RS10370	COG1105	Belongs to the carbohydrate kinase PfkB family
PGS39_RS10375	COG3684	Belongs to the aldolase LacD family
PGS39_RS10380	COG0366	Alpha amylase catalytic
PGS39_RS10385	COG0366	Alpha amylase catalytic
PGS39_RS10390	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PGS39_RS10395	COG0640	Transcriptional regulator
PGS39_RS10400	COG0667	Aldo Keto reductase
PGS39_RS10405	COG2814	Major facilitator Superfamily
PGS39_RS10430	COG0840	transmembrane signaling receptor activity
PGS39_RS10445	COG3949	Membrane
PGS39_RS10450	COG0783	Belongs to the Dps family
PGS39_RS10465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGS39_RS10475	COG1231	oxidoreductase activity
PGS39_RS10480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS10485	COG4989	oxidoreductase activity
PGS39_RS10490	COG0523	cobalamin synthesis protein
PGS39_RS10495	COG0456	acetyltransferase
PGS39_RS10500	COG0803	Belongs to the bacterial solute-binding protein 9 family
PGS39_RS10500	COG3443	Belongs to the bacterial solute-binding protein 9 family
PGS39_RS10510	COG0702	epimerase
PGS39_RS10520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGS39_RS10530	COG4166	transmembrane transport
PGS39_RS10545	COG0406	alpha-ribazole phosphatase activity
PGS39_RS10555	COG5337	Spore coat protein CotH
PGS39_RS10560	COG1051	belongs to the nudix hydrolase family
PGS39_RS10565	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS10570	COG2244	polysaccharide biosynthetic process
PGS39_RS10580	COG0701	Predicted permease
PGS39_RS10585	COG3689	TIGRFAM TIGR03943 family protein
PGS39_RS10590	COG1607	acyl-coa hydrolase
PGS39_RS10600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS10615	COG0702	epimerase
PGS39_RS10620	COG2839	Protein conserved in bacteria
PGS39_RS10625	COG1253	flavin adenine dinucleotide binding
PGS39_RS10640	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS10645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGS39_RS10665	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS10675	COG1876	peptidase activity
PGS39_RS10685	COG0154	amidase activity
PGS39_RS10690	COG2211	Major facilitator Superfamily
PGS39_RS10710	COG0561	phosphatase activity
PGS39_RS10720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGS39_RS10725	COG4106	trans-aconitate 2-methyltransferase activity
PGS39_RS10740	COG1819	glycosyl
PGS39_RS10745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS10750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS10780	COG0456	acetyltransferase
PGS39_RS10805	COG3874	Sporulation protein YtfJ
PGS39_RS10830	COG2226	methyltransferase
PGS39_RS10855	COG0582	viral genome integration into host DNA
PGS39_RS10870	COG3620	sequence-specific DNA binding
PGS39_RS10910	COG2002	toxin-antitoxin pair type II binding
PGS39_RS10980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PGS39_RS10985	COG0582	viral genome integration into host DNA
PGS39_RS11020	COG4626	Terminase
PGS39_RS11020	COG1802	Transcriptional regulator
PGS39_RS11030	COG0740	serine-type endopeptidase activity
PGS39_RS11110	COG4824	toxin secretion phage lysis holin
PGS39_RS11165	COG0604	alcohol dehydrogenase
PGS39_RS11170	COG1595	DNA-templated transcription, initiation
PGS39_RS11185	COG0426	domain, Protein
PGS39_RS11185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGS39_RS11195	COG0386	Belongs to the glutathione peroxidase family
PGS39_RS11200	COG1305	Transglutaminase-like
PGS39_RS11205	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
PGS39_RS11210	COG0714	Associated with various cellular activities
PGS39_RS11215	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGS39_RS11220	COG1140	nitrate reductase beta subunit
PGS39_RS11225	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PGS39_RS11230	COG2181	nitrate reductase activity
PGS39_RS11235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PGS39_RS11240	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGS39_RS11245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGS39_RS11250	COG0303	'Molybdopterin
PGS39_RS11255	COG0314	molybdopterin synthase activity
PGS39_RS11265	COG2223	nitrite transmembrane transporter activity
PGS39_RS11285	COG1648	precorrin-2 dehydrogenase activity
PGS39_RS11295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PGS39_RS11295	COG1587	Uroporphyrinogen-III synthase
PGS39_RS11300	COG2146	nitrite reductase [NAD(P)H] activity
PGS39_RS11305	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PGS39_RS11310	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PGS39_RS11345	COG2359	stage V sporulation protein S
PGS39_RS11365	COG1418	mRNA catabolic process
PGS39_RS11370	COG0488	(ABC) transporter
PGS39_RS11385	COG0629	single-stranded DNA binding
PGS39_RS11400	COG1413	lyase activity
PGS39_RS11475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PGS39_RS11480	COG0017	Asparaginyl-tRNA synthetase
PGS39_RS11485	COG0733	neurotransmitter:sodium symporter activity
PGS39_RS11510	COG2610	gluconate transmembrane transporter activity
PGS39_RS11515	COG1454	alcohol dehydrogenase
PGS39_RS11520	COG1794	racemase activity, acting on amino acids and derivatives
PGS39_RS11530	COG0456	acetyltransferase
PGS39_RS11535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PGS39_RS11545	COG1131	(ABC) transporter
PGS39_RS11550	COG4473	ABC transporter
PGS39_RS11560	COG0546	phosphoglycolate phosphatase activity
PGS39_RS11575	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PGS39_RS11580	COG3250	beta-galactosidase activity
PGS39_RS11595	COG0768	penicillin binding
PGS39_RS11605	COG0204	Acyl-transferase
PGS39_RS11610	COG1272	protein, Hemolysin III
PGS39_RS11620	COG0805	protein transport
PGS39_RS11630	COG1307	EDD domain protein, DegV family
PGS39_RS11635	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PGS39_RS11640	COG1999	signal sequence binding
PGS39_RS11645	COG0071	Belongs to the small heat shock protein (HSP20) family
PGS39_RS11650	COG0367	asparagine synthase
PGS39_RS11670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS11675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PGS39_RS11700	COG0571	ribonuclease III activity
PGS39_RS11765	COG1051	belongs to the nudix hydrolase family
PGS39_RS11775	COG0668	transmembrane transport
PGS39_RS11780	COG4585	Histidine kinase
PGS39_RS11780	COG2203	Gaf domain
PGS39_RS11785	COG2197	response regulator
PGS39_RS11795	COG1064	alcohol dehydrogenase
PGS39_RS11850	COG1125	glycine betaine transport
PGS39_RS11850	COG0517	IMP dehydrogenase activity
PGS39_RS11855	COG1174	glycine betaine transport
PGS39_RS11890	COG1253	flavin adenine dinucleotide binding
PGS39_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS11900	COG5506	Protein of unknown function (DUF1694)
PGS39_RS11915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGS39_RS11920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PGS39_RS11925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PGS39_RS11930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PGS39_RS11935	COG0456	acetyltransferase
PGS39_RS11940	COG3829	transcription factor binding
PGS39_RS11945	COG1509	lysine 2,3-aminomutase activity
PGS39_RS11980	COG0515	serine threonine protein kinase
PGS39_RS11980	COG4991	sh3 domain protein
PGS39_RS11980	COG3064	Membrane
PGS39_RS11985	COG4326	sporulation control protein
PGS39_RS11990	COG0671	phosphoesterase, PA-phosphatase related
PGS39_RS11995	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGS39_RS12000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS12020	COG5484	DNA packaging
PGS39_RS12020	COG3728	DNA packaging
PGS39_RS12055	COG1595	DNA-templated transcription, initiation
PGS39_RS12085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PGS39_RS12140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGS39_RS12140	COG4499	WXG100 protein secretion system (Wss), protein YukC
PGS39_RS12150	COG2814	Major facilitator Superfamily
PGS39_RS12155	COG4841	protein insertion into membrane
PGS39_RS12160	COG0372	Belongs to the citrate synthase family
PGS39_RS12165	COG2079	MmgE PrpD family protein
PGS39_RS12170	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PGS39_RS12175	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS12180	COG2084	Dehydrogenase
PGS39_RS12190	COG1280	lysine exporter protein (LysE YggA)
PGS39_RS12195	COG1024	Enoyl-CoA hydratase
PGS39_RS12210	COG0420	3'-5' exonuclease activity
PGS39_RS12240	COG2223	nitrite transmembrane transporter activity
PGS39_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS12250	COG1169	isochorismate synthase
PGS39_RS12255	COG1021	2,3-dihydroxybenzoate-AMP ligase
PGS39_RS12260	COG3433	isochorismatase activity
PGS39_RS12260	COG1535	isochorismatase
PGS39_RS12265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PGS39_RS12275	COG2814	Major facilitator Superfamily
PGS39_RS12290	COG0776	regulation of translation
PGS39_RS12300	COG2318	DinB family
PGS39_RS12310	COG1115	amino acid carrier protein
PGS39_RS12335	COG2329	Antibiotic biosynthesis monooxygenase
PGS39_RS12340	COG1187	pseudouridine synthase activity
PGS39_RS12345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGS39_RS12350	COG1136	(ABC) transporter
PGS39_RS12360	COG2814	Major facilitator Superfamily
PGS39_RS12375	COG0028	Belongs to the TPP enzyme family
PGS39_RS12385	COG2226	methyltransferase
PGS39_RS12455	COG1247	-acetyltransferase
PGS39_RS12480	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PGS39_RS12485	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PGS39_RS12495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS12505	COG1278	Cold shock
PGS39_RS12520	COG0010	Belongs to the arginase family
PGS39_RS12525	COG0561	phosphatase activity
PGS39_RS12535	COG1846	Transcriptional regulator
PGS39_RS12540	COG2814	Major facilitator Superfamily
PGS39_RS12545	COG0583	DNA-binding transcription factor activity
PGS39_RS12550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGS39_RS12565	COG0583	DNA-binding transcription factor activity
PGS39_RS12570	COG2258	MOSC domain
PGS39_RS12585	COG1132	(ABC) transporter
PGS39_RS12590	COG1132	(ABC) transporter
PGS39_RS12605	COG1396	sequence-specific DNA binding
PGS39_RS12645	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
PGS39_RS12650	COG1595	DNA-templated transcription, initiation
PGS39_RS12675	COG1649	PFAM Uncharacterised BCR, COG1649
PGS39_RS12700	COG2971	BadF BadG BcrA BcrD
PGS39_RS12710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PGS39_RS12730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS12765	COG1309	transcriptional regulator
PGS39_RS12780	COG0577	efflux transmembrane transporter activity
PGS39_RS12780	COG1136	(ABC) transporter
PGS39_RS12785	COG0500	methyltransferase
PGS39_RS12785	COG3615	Tellurite resistance protein tehB
PGS39_RS12800	COG3961	Belongs to the TPP enzyme family
PGS39_RS12830	COG2195	Cleaves the N-terminal amino acid of tripeptides
PGS39_RS12845	COG1595	DNA-templated transcription, initiation
PGS39_RS12855	COG0768	penicillin binding
PGS39_RS12860	COG0768	penicillin binding
PGS39_RS12865	COG2367	Beta-lactamase
PGS39_RS12870	COG1408	metallophosphoesterase
PGS39_RS12880	COG1131	(ABC) transporter
PGS39_RS12890	COG1309	transcriptional regulator
PGS39_RS12905	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS12910	COG0439	Biotin carboxylase
PGS39_RS12915	COG0511	ligase activity, forming carbon-carbon bonds
PGS39_RS12920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGS39_RS12925	COG1024	Enoyl-CoA hydratase
PGS39_RS12930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PGS39_RS12935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PGS39_RS12950	COG0572	uridine kinase
PGS39_RS12960	COG2318	DinB family
PGS39_RS12965	COG1686	Belongs to the peptidase S11 family
PGS39_RS12990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGS39_RS13010	COG3227	Zinc metalloprotease (Elastase)
PGS39_RS13045	COG2814	Major facilitator Superfamily
PGS39_RS13055	COG2226	methyltransferase
PGS39_RS13085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS13100	COG1063	alcohol dehydrogenase
PGS39_RS13110	COG2323	membrane
PGS39_RS13115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PGS39_RS13130	COG3386	PFAM SMP-30 Gluconolaconase
PGS39_RS13140	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
PGS39_RS13145	COG3773	Cell wall hydrolase
PGS39_RS13155	COG0745	RESPONSE REGULATOR receiver
PGS39_RS13160	COG2205	protein histidine kinase activity
PGS39_RS13170	COG0488	(ABC) transporter
PGS39_RS13175	COG1136	(ABC) transporter
PGS39_RS13180	COG0577	efflux transmembrane transporter activity
PGS39_RS13200	COG0460	homoserine dehydrogenase
PGS39_RS13205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS13215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGS39_RS13350	COG2124	cytochrome p450
PGS39_RS13380	COG0561	phosphatase activity
PGS39_RS13385	COG5002	protein histidine kinase activity
PGS39_RS13390	COG0768	penicillin binding
PGS39_RS13400	COG1794	racemase activity, acting on amino acids and derivatives
PGS39_RS13425	COG2205	protein histidine kinase activity
PGS39_RS13435	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGS39_RS13440	COG0604	alcohol dehydrogenase
PGS39_RS13445	COG0671	phosphoesterase, PA-phosphatase related
PGS39_RS13450	COG0768	penicillin binding
PGS39_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS13520	COG0584	glycerophosphoryl diester phosphodiesterase
PGS39_RS13550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS13555	COG0697	spore germination
PGS39_RS13565	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGS39_RS13580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PGS39_RS13590	COG2223	nitrite transmembrane transporter activity
PGS39_RS13605	COG2816	NAD+ diphosphatase activity
PGS39_RS13610	COG0592	DNA-directed DNA polymerase activity
PGS39_RS13615	COG1051	belongs to the nudix hydrolase family
PGS39_RS13645	COG3878	Protein conserved in bacteria
PGS39_RS13675	COG4667	esterase of the alpha-beta hydrolase superfamily
PGS39_RS13715	COG0322	excinuclease ABC activity
PGS39_RS13745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGS39_RS13770	COG1011	Hydrolase
PGS39_RS13790	COG1523	belongs to the glycosyl hydrolase 13 family
PGS39_RS13795	COG3227	Zinc metalloprotease (Elastase)
PGS39_RS13805	COG0346	lactoylglutathione lyase activity
PGS39_RS13810	COG0201	protein transport
PGS39_RS13865	COG2959	enzyme of heme biosynthesis
PGS39_RS13905	COG1309	transcriptional regulator
PGS39_RS13935	COG3284	Transcriptional regulator
PGS39_RS13955	COG1349	DNA-binding transcription factor activity
PGS39_RS13970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGS39_RS13975	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGS39_RS13980	COG0022	dehydrogenase e1 component
PGS39_RS13985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PGS39_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS14000	COG0456	acetyltransferase
PGS39_RS14000	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGS39_RS14005	COG0572	uridine kinase
PGS39_RS14040	COG4176	ABC-type proline glycine betaine transport system permease component
PGS39_RS14045	COG0517	IMP dehydrogenase activity
PGS39_RS14045	COG4175	Glycine betaine
PGS39_RS14070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGS39_RS14075	COG2153	protein acetylation
PGS39_RS14080	COG3397	chitin binding
PGS39_RS14085	COG1819	glycosyl
PGS39_RS14100	COG2205	protein histidine kinase activity
PGS39_RS14105	COG2226	methyltransferase
PGS39_RS14110	COG2315	Protein conserved in bacteria
PGS39_RS14120	COG0658	competence protein
PGS39_RS14120	COG2333	competence protein COMEC
PGS39_RS14160	COG3973	AAA domain
PGS39_RS14180	COG0514	ATP-dependent DNA helicase (RecQ)
PGS39_RS14210	COG4637	Psort location Cytoplasmic, score
PGS39_RS14230	COG3397	chitin binding
PGS39_RS14250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGS39_RS14255	COG1115	amino acid carrier protein
PGS39_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS14265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGS39_RS14275	COG3938	Belongs to the proline racemase family
PGS39_RS14280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGS39_RS14325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGS39_RS14330	COG0519	Catalyzes the synthesis of GMP from XMP
PGS39_RS14335	COG4166	transmembrane transport
PGS39_RS14345	COG4948	Mandelate Racemase Muconate Lactonizing
PGS39_RS14395	COG2936	dipeptidyl-peptidase activity
PGS39_RS14400	COG5002	protein histidine kinase activity
PGS39_RS14405	COG0745	RESPONSE REGULATOR receiver
PGS39_RS14440	COG1164	Oligoendopeptidase f
PGS39_RS14450	COG1307	EDD domain protein, DegV family
PGS39_RS14490	COG2814	Major facilitator Superfamily
PGS39_RS14500	COG1664	Polymer-forming cytoskeletal
PGS39_RS14505	COG0789	Transcriptional regulator
PGS39_RS14510	COG4533	DNA binding
PGS39_RS14515	COG0477	Major facilitator Superfamily
PGS39_RS14515	COG2814	Major facilitator Superfamily
PGS39_RS14540	COG2261	transglycosylase associated protein
PGS39_RS14555	COG2226	methyltransferase
PGS39_RS14585	COG0436	Aminotransferase
PGS39_RS14590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PGS39_RS14595	COG5146	pantothenate kinase activity
PGS39_RS14600	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PGS39_RS14660	COG0628	permease
PGS39_RS14675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGS39_RS14680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGS39_RS14685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PGS39_RS14730	COG2746	aminoglycoside 3-N-acetyltransferase activity
PGS39_RS14750	COG0697	spore germination
PGS39_RS14755	COG2318	DinB family
PGS39_RS14775	COG4912	Dna alkylation repair
PGS39_RS14785	COG0346	lactoylglutathione lyase activity
PGS39_RS14805	COG0861	Integral membrane protein TerC family
PGS39_RS14810	COG1368	sulfuric ester hydrolase activity
PGS39_RS14815	COG0488	(ABC) transporter
PGS39_RS14825	COG1033	growth of symbiont in host cell
PGS39_RS14825	COG2409	Drug exporters of the RND superfamily
PGS39_RS14830	COG1309	transcriptional regulator
PGS39_RS14845	COG0287	Prephenate dehydrogenase
PGS39_RS14850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGS39_RS14860	COG1605	Chorismate mutase
PGS39_RS14860	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PGS39_RS14890	COG1388	LysM domain
PGS39_RS14890	COG3584	3D domain protein
PGS39_RS14915	COG1172	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS14925	COG2390	Transcriptional regulator
PGS39_RS14930	COG1070	Carbohydrate kinase
PGS39_RS14950	COG2329	Antibiotic biosynthesis monooxygenase
PGS39_RS14965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS14980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGS39_RS14985	COG4187	Peptidase family M20/M25/M40
PGS39_RS14990	COG1414	Transcriptional regulator
PGS39_RS14995	COG0833	amino acid
PGS39_RS15000	COG1690	Belongs to the RtcB family
PGS39_RS15005	COG3239	Fatty acid desaturase
PGS39_RS15015	COG1785	Belongs to the alkaline phosphatase family
PGS39_RS15025	COG3655	Transcriptional regulator
PGS39_RS15040	COG4377	Putative membrane peptidase family (DUF2324)
PGS39_RS15050	COG3279	Response regulator of the LytR AlgR family
PGS39_RS15065	COG0346	lactoylglutathione lyase activity
PGS39_RS15085	COG0714	Associated with various cellular activities
PGS39_RS15105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PGS39_RS15110	COG0753	catalase activity
PGS39_RS15115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGS39_RS15135	COG1846	Transcriptional regulator
PGS39_RS15140	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PGS39_RS15165	COG0714	Associated with various cellular activities
PGS39_RS15175	COG0778	Nitroreductase
PGS39_RS15180	COG1846	Transcriptional regulator
PGS39_RS15215	COG1725	Transcriptional regulator
PGS39_RS15225	COG1136	(ABC) transporter
PGS39_RS15255	COG0456	acetyltransferase
PGS39_RS15270	COG0697	spore germination
PGS39_RS15275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS15315	COG0730	response to heat
PGS39_RS15325	COG0833	amino acid
PGS39_RS15335	COG4335	DNA alkylation repair
PGS39_RS15375	COG0768	penicillin binding
PGS39_RS15410	COG1984	allophanate hydrolase subunit 2
PGS39_RS15415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PGS39_RS15420	COG1414	Transcriptional regulator
PGS39_RS15430	COG3142	Participates in the control of copper homeostasis
PGS39_RS15435	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS15440	COG0640	Transcriptional regulator
PGS39_RS15450	COG2814	Major facilitator Superfamily
PGS39_RS15460	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS15475	COG3314	Sporulation integral membrane protein YlbJ
PGS39_RS15500	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
PGS39_RS15515	COG0574	Belongs to the PEP-utilizing enzyme family
PGS39_RS15515	COG3848	Pyruvate phosphate dikinase
PGS39_RS15525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS15540	COG5577	PFAM Coat F domain
PGS39_RS15545	COG3403	YqcI/YcgG family
PGS39_RS15550	COG1280	lysine exporter protein (LysE YggA)
PGS39_RS15555	COG1113	amino acid transport
PGS39_RS15585	COG1063	alcohol dehydrogenase
PGS39_RS15595	COG1027	Aspartate ammonia-lyase
PGS39_RS15600	COG0252	asparaginase activity
PGS39_RS15605	COG1396	sequence-specific DNA binding
PGS39_RS15615	COG0322	excinuclease ABC activity
PGS39_RS15620	COG0531	amino acid
PGS39_RS15625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGS39_RS15635	COG0531	amino acid
PGS39_RS15640	COG0697	spore germination
PGS39_RS15645	COG0784	Response regulator, receiver
PGS39_RS15650	COG4191	Histidine kinase
PGS39_RS15655	COG2066	Belongs to the glutaminase family
PGS39_RS15660	COG1115	amino acid carrier protein
PGS39_RS15680	COG0723	plastoquinol--plastocyanin reductase activity
PGS39_RS15680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PGS39_RS15685	COG0534	Mate efflux family protein
PGS39_RS15695	COG0531	amino acid
PGS39_RS15700	COG0737	Belongs to the 5'-nucleotidase family
PGS39_RS15705	COG0753	catalase activity
PGS39_RS15715	COG0598	Magnesium transport protein CorA
PGS39_RS15770	COG0415	Belongs to the DNA photolyase family
PGS39_RS15785	COG0288	reversible hydration of carbon dioxide
PGS39_RS15795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PGS39_RS15800	COG5609	conserved protein (DUF2294)
PGS39_RS15815	COG0697	spore germination
PGS39_RS15825	COG1575	Belongs to the MenA family. Type 1 subfamily
PGS39_RS15830	COG4641	Protein conserved in bacteria
PGS39_RS15855	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS15855	COG3347	Dehydrogenase
PGS39_RS15865	COG1070	Carbohydrate kinase
PGS39_RS15870	COG0235	Class ii aldolase
PGS39_RS15880	COG1172	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS15890	COG4154	Belongs to the RbsD FucU family
PGS39_RS15905	COG0798	PFAM Bile acid sodium symporter
PGS39_RS15910	COG0346	lactoylglutathione lyase activity
PGS39_RS15915	COG0640	Transcriptional regulator
PGS39_RS15925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGS39_RS15945	COG1136	(ABC) transporter
PGS39_RS15990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGS39_RS15990	COG3320	Male sterility
PGS39_RS15995	COG1309	transcriptional regulator
PGS39_RS16000	COG2814	Major facilitator Superfamily
PGS39_RS16005	COG1309	transcriptional regulator
PGS39_RS16010	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS16015	COG1522	sequence-specific DNA binding
PGS39_RS16030	COG0346	lactoylglutathione lyase activity
PGS39_RS16065	COG2814	Major facilitator Superfamily
PGS39_RS16075	COG4895	conserved protein (DUF2196)
PGS39_RS16125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PGS39_RS16145	COG0789	Transcriptional regulator
PGS39_RS16150	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PGS39_RS16170	COG0577	efflux transmembrane transporter activity
PGS39_RS16190	COG3850	Histidine kinase
PGS39_RS16190	COG5002	protein histidine kinase activity
PGS39_RS16200	COG2364	Membrane
PGS39_RS16205	COG1846	Transcriptional regulator
PGS39_RS16210	COG0456	acetyltransferase
PGS39_RS16215	COG2808	Putative FMN-binding domain
PGS39_RS16220	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS16250	COG1619	proteins homologs of microcin C7 resistance protein MccF
PGS39_RS16265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PGS39_RS16285	COG0662	Cupin 2, conserved barrel domain protein
PGS39_RS16290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS16290	COG2207	Transcriptional regulator
PGS39_RS16310	COG5632	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS16310	COG3409	Peptidoglycan-binding domain 1 protein
PGS39_RS16350	COG0477	Major facilitator Superfamily
PGS39_RS16365	COG1846	Transcriptional regulator
PGS39_RS16370	COG2814	Major facilitator Superfamily
PGS39_RS16380	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PGS39_RS16385	COG1131	(ABC) transporter
PGS39_RS16405	COG2076	Multidrug Resistance protein
PGS39_RS16410	COG1309	transcriptional regulator
PGS39_RS16425	COG2031	fatty acid transporter
PGS39_RS16435	COG2249	NAD(P)H dehydrogenase (quinone) activity
PGS39_RS16475	COG3344	reverse transcriptase
PGS39_RS16495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PGS39_RS16500	COG1288	antiporter activity
PGS39_RS16520	COG0789	Transcriptional regulator
PGS39_RS16540	COG3344	reverse transcriptase
PGS39_RS16545	COG0456	acetyltransferase
PGS39_RS16545	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGS39_RS16550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGS39_RS16570	COG1733	regulation of RNA biosynthetic process
PGS39_RS16575	COG0778	Nitroreductase
PGS39_RS16595	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS16605	COG1131	(ABC) transporter
PGS39_RS16630	COG1011	Hydrolase
PGS39_RS16635	COG2365	Tyrosine phosphatase family
PGS39_RS16655	COG0346	lactoylglutathione lyase activity
PGS39_RS16660	COG1940	carbohydrate kinase activity
PGS39_RS16665	COG0110	maltose O-acetyltransferase activity
PGS39_RS16680	COG0628	permease
PGS39_RS16710	COG2226	methyltransferase
PGS39_RS16720	COG0477	Major facilitator Superfamily
PGS39_RS16745	COG1253	flavin adenine dinucleotide binding
PGS39_RS16750	COG0789	Transcriptional regulator
PGS39_RS16760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PGS39_RS16790	COG0697	spore germination
PGS39_RS16795	COG1357	PFAM Pentapeptide repeats (8 copies)
PGS39_RS16800	COG3813	Protein conserved in bacteria
PGS39_RS16805	COG2706	6-phosphogluconolactonase activity
PGS39_RS16810	COG1070	Carbohydrate kinase
PGS39_RS16820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PGS39_RS16825	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PGS39_RS16835	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGS39_RS16840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGS39_RS16845	COG0604	alcohol dehydrogenase
PGS39_RS16850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGS39_RS16860	COG3321	synthase
PGS39_RS16860	COG0604	alcohol dehydrogenase
PGS39_RS16865	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS16880	COG0656	L-ascorbic acid biosynthetic process
PGS39_RS16885	COG2814	Major facilitator Superfamily
PGS39_RS16900	COG0814	amino acid
PGS39_RS16905	COG3344	reverse transcriptase
PGS39_RS16930	COG1393	Belongs to the ArsC family
PGS39_RS16935	COG1733	regulation of RNA biosynthetic process
PGS39_RS16940	COG2188	Transcriptional regulator
PGS39_RS16945	COG0673	inositol 2-dehydrogenase activity
PGS39_RS16950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PGS39_RS16955	COG1733	regulation of RNA biosynthetic process
PGS39_RS16960	COG1733	regulation of RNA biosynthetic process
PGS39_RS16980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS17000	COG0384	phenazine biosynthesis protein PhzF
PGS39_RS17020	COG0318	PFAM AMP-dependent synthetase and ligase
PGS39_RS17025	COG2249	NAD(P)H dehydrogenase (quinone) activity
PGS39_RS17030	COG1733	regulation of RNA biosynthetic process
PGS39_RS17065	COG1309	transcriptional regulator
PGS39_RS17110	COG1151	hydroxylamine reductase activity
PGS39_RS17120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS17150	COG2072	flavoprotein involved in K transport
PGS39_RS17195	COG1695	Transcriptional regulator
PGS39_RS17200	COG0604	alcohol dehydrogenase
PGS39_RS17205	COG1113	amino acid transport
PGS39_RS17210	COG2814	Major facilitator Superfamily
PGS39_RS17235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PGS39_RS17240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGS39_RS17255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS17260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS17265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS17270	COG3739	integral membrane protein
PGS39_RS17300	COG0583	DNA-binding transcription factor activity
PGS39_RS17320	COG1193	negative regulation of DNA recombination
PGS39_RS17325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
PGS39_RS17330	COG1164	Oligoendopeptidase f
PGS39_RS17335	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PGS39_RS17365	COG0584	glycerophosphoryl diester phosphodiesterase
PGS39_RS17375	COG0640	Transcriptional regulator
PGS39_RS17380	COG0604	alcohol dehydrogenase
PGS39_RS17390	COG0457	Tetratricopeptide repeat
PGS39_RS17400	COG2808	Putative FMN-binding domain
PGS39_RS17405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGS39_RS17415	COG0385	Bile acid
PGS39_RS17420	COG0277	FAD linked oxidase domain protein
PGS39_RS17450	COG1285	pathogenesis
PGS39_RS17465	COG2514	catechol 2,3-dioxygenase activity
PGS39_RS17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS17475	COG1126	abc transporter atp-binding protein
PGS39_RS17480	COG0765	amino acid transport
PGS39_RS17485	COG2720	vancomycin resistance protein
PGS39_RS17525	COG0716	FMN binding
PGS39_RS17535	COG0494	nUDIX hydrolase
PGS39_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS17565	COG0165	Argininosuccinate lyase
PGS39_RS17580	COG4145	pantothenate transmembrane transporter activity
PGS39_RS17630	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS17645	COG1657	PFAM Prenyltransferase squalene oxidase
PGS39_RS17650	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
PGS39_RS17655	COG2962	Rard protein
PGS39_RS17660	COG3326	Membrane
PGS39_RS17675	COG0489	protein tyrosine kinase activity
PGS39_RS17685	COG0314	molybdopterin synthase activity
PGS39_RS17690	COG0303	'Molybdopterin
PGS39_RS17695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGS39_RS17700	COG2116	formate transmembrane transporter activity
PGS39_RS17710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PGS39_RS17715	COG5609	conserved protein (DUF2294)
PGS39_RS17720	COG2427	Protein of unknown function (DUF1641)
PGS39_RS17725	COG3383	formate dehydrogenase (NAD+) activity
PGS39_RS17730	COG0697	spore germination
PGS39_RS17770	COG2226	methyltransferase
PGS39_RS17775	COG4166	transmembrane transport
PGS39_RS17780	COG4166	transmembrane transport
PGS39_RS17785	COG4166	transmembrane transport
PGS39_RS17790	COG1301	dicarboxylic acid transport
PGS39_RS17795	COG1316	TRANSCRIPTIONal
PGS39_RS17805	COG1595	DNA-templated transcription, initiation
PGS39_RS17810	COG0346	lactoylglutathione lyase activity
PGS39_RS17820	COG1131	(ABC) transporter
PGS39_RS17830	COG0673	inositol 2-dehydrogenase activity
PGS39_RS17835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGS39_RS17840	COG0187	DNA topoisomerase II activity
PGS39_RS17845	COG1832	CoA-binding protein
PGS39_RS17850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGS39_RS17855	COG0745	RESPONSE REGULATOR receiver
PGS39_RS17865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGS39_RS17865	COG1328	CTP reductase activity
PGS39_RS17875	COG4841	protein insertion into membrane
PGS39_RS17880	COG0824	Thioesterase
PGS39_RS17910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS17920	COG1132	(ABC) transporter
PGS39_RS17925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PGS39_RS17955	COG2211	Major facilitator Superfamily
PGS39_RS17955	COG2211	Major facilitator Superfamily
PGS39_RS17960	COG4282	regulation of fungal-type cell wall biogenesis
PGS39_RS17980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGS39_RS18005	COG0183	Belongs to the thiolase family
PGS39_RS18010	COG0318	PFAM AMP-dependent synthetase and ligase
PGS39_RS18015	COG1268	BioY protein
PGS39_RS18020	COG0318	PFAM AMP-dependent synthetase and ligase
PGS39_RS18035	COG1396	sequence-specific DNA binding
PGS39_RS18080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS18090	COG5002	protein histidine kinase activity
PGS39_RS18095	COG0400	carboxylic ester hydrolase activity
PGS39_RS18100	COG0346	lactoylglutathione lyase activity
PGS39_RS18105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGS39_RS18115	COG0069	glutamate synthase activity
PGS39_RS18120	COG1902	pentaerythritol trinitrate reductase activity
PGS39_RS18125	COG1329	Transcriptional regulator
PGS39_RS18130	COG0010	Belongs to the arginase family
PGS39_RS18155	COG2226	methyltransferase
PGS39_RS18195	COG3344	reverse transcriptase
PGS39_RS18205	COG4846	Membrane protein involved in cytochrome C biogenesis
PGS39_RS18210	COG0785	Cytochrome C biogenesis protein
PGS39_RS18220	COG1473	amidohydrolase
PGS39_RS18230	COG1131	(ABC) transporter
PGS39_RS18240	COG0583	DNA-binding transcription factor activity
PGS39_RS18250	COG1346	cytolysis
PGS39_RS18265	COG0730	response to heat
PGS39_RS18275	COG3409	Peptidoglycan-binding domain 1 protein
PGS39_RS18275	COG5632	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS18290	COG1132	(ABC) transporter
PGS39_RS18295	COG1132	(ABC) transporter
PGS39_RS18415	COG3639	organic phosphonate transmembrane transporter activity
PGS39_RS18420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PGS39_RS18425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS18430	COG0737	Belongs to the 5'-nucleotidase family
PGS39_RS18440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PGS39_RS18460	COG1695	Transcriptional regulator
PGS39_RS18465	COG0174	glutamine synthetase
PGS39_RS18470	COG0789	Transcriptional regulator
PGS39_RS18475	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
PGS39_RS18480	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGS39_RS18485	COG2860	membrane
PGS39_RS18495	COG0464	growth
PGS39_RS18525	COG1388	LysM domain
PGS39_RS18525	COG3584	3D domain protein
PGS39_RS18530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PGS39_RS18530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PGS39_RS18530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PGS39_RS18535	COG1105	Belongs to the carbohydrate kinase PfkB family
PGS39_RS18540	COG1349	DNA-binding transcription factor activity
PGS39_RS18545	COG1979	alcohol dehydrogenase
PGS39_RS18550	COG2322	membrane
PGS39_RS18560	COG1113	amino acid transport
PGS39_RS18570	COG1408	metallophosphoesterase
PGS39_RS18575	COG2116	formate transmembrane transporter activity
PGS39_RS18590	COG2217	Heavy metal translocating P-type atpase
PGS39_RS18595	COG2608	mercury ion transmembrane transporter activity
PGS39_RS18600	COG1937	Protein conserved in bacteria
PGS39_RS18610	COG2819	hydrolase of the alpha beta superfamily
PGS39_RS18615	COG1120	ATPase activity
PGS39_RS18620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS18625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS18630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS18640	COG2169	Transcriptional regulator
PGS39_RS18645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGS39_RS18650	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PGS39_RS18660	COG2364	Membrane
PGS39_RS18670	COG5001	Diguanylate cyclase
PGS39_RS18670	COG3300	MHYT domain
PGS39_RS18690	COG1380	Effector of murein hydrolase LrgA
PGS39_RS18695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS18715	COG3773	Cell wall hydrolase
PGS39_RS18725	COG1368	sulfuric ester hydrolase activity
PGS39_RS18730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGS39_RS18740	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
PGS39_RS18765	COG1131	(ABC) transporter
PGS39_RS18790	COG4550	Control of competence regulator ComK, YlbF/YmcA
PGS39_RS18800	COG1013	pyruvate-flavodoxin oxidoreductase activity
PGS39_RS18805	COG0674	pyruvate-flavodoxin oxidoreductase activity
PGS39_RS18805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PGS39_RS18815	COG2359	stage V sporulation protein S
PGS39_RS18820	COG1692	metallophosphoesterase
PGS39_RS18825	COG1418	mRNA catabolic process
PGS39_RS18845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGS39_RS18850	COG1426	Protein conserved in bacteria
PGS39_RS18865	COG0300	oxidoreductase activity
PGS39_RS18870	COG0612	Peptidase, M16
PGS39_RS18875	COG0612	Peptidase, M16
PGS39_RS18880	COG1079	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS18885	COG4603	Belongs to the binding-protein-dependent transport system permease family
PGS39_RS18890	COG3845	ABC transporter
PGS39_RS18895	COG1744	ABC transporter substrate-binding protein PnrA-like
PGS39_RS18900	COG2188	Transcriptional regulator
PGS39_RS18905	COG1674	ftsk spoiiie
PGS39_RS18915	COG0740	serine-type endopeptidase activity
PGS39_RS18920	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGS39_RS18930	COG0527	aspartate kinase activity
PGS39_RS18935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGS39_RS18940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGS39_RS18945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGS39_RS18950	COG1873	PFAM PRC-barrel domain
PGS39_RS18955	COG0612	Peptidase, M16
PGS39_RS18960	COG0726	polysaccharide deacetylase
PGS39_RS18975	COG0196	riboflavin kinase activity
PGS39_RS18990	COG1550	Protein conserved in bacteria
PGS39_RS19000	COG1358	cellular component organization or biogenesis
PGS39_RS19005	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PGS39_RS19010	COG0195	Participates in both transcription termination and antitermination
PGS39_RS19030	COG0750	zinc metalloprotease
PGS39_RS19040	COG4589	Belongs to the CDS family
PGS39_RS19055	COG0528	UMP kinase activity
PGS39_RS19085	COG4974	Belongs to the 'phage' integrase family
PGS39_RS19095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGS39_RS19100	COG0758	DNA mediated transformation
PGS39_RS19105	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PGS39_RS19145	COG1837	Belongs to the UPF0109 family
PGS39_RS19155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGS39_RS19165	COG0552	protein localization to endoplasmic reticulum
PGS39_RS19170	COG1196	nuclear chromosome segregation
PGS39_RS19180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGS39_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS19190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PGS39_RS19205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGS39_RS19210	COG1461	Dihydroxyacetone kinase
PGS39_RS19215	COG1302	Protein conserved in bacteria
PGS39_RS19230	COG1564	THIamine pyrophosphokinase
PGS39_RS19235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PGS39_RS19245	COG0515	serine threonine protein kinase
PGS39_RS19245	COG2815	serine threonine protein kinase
PGS39_RS19250	COG0631	protein serine/threonine phosphatase activity
PGS39_RS19260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGS39_RS19260	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGS39_RS19270	COG0242	peptide deformylase activity
PGS39_RS19275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGS39_RS19280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGS39_RS19300	COG1561	YicC-like family, N-terminal region
PGS39_RS19305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PGS39_RS19315	COG0006	proline dipeptidase activity
PGS39_RS19335	COG3069	C4-dicarboxylate transmembrane transporter activity
PGS39_RS19400	COG0564	pseudouridine synthase activity
PGS39_RS19420	COG3599	regulation of cell shape
PGS39_RS19425	COG2302	S4 RNA-binding domain
PGS39_RS19430	COG0762	integral membrane protein
PGS39_RS19440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PGS39_RS19450	COG1873	PFAM PRC-barrel domain
PGS39_RS19455	COG1191	sigma factor activity
PGS39_RS19460	COG1191	sigma factor activity
PGS39_RS19470	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGS39_RS19475	COG0849	cell division
PGS39_RS19480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PGS39_RS19495	COG0772	Belongs to the SEDS family
PGS39_RS19510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGS39_RS19515	COG0768	penicillin binding
PGS39_RS19520	COG0768	penicillin binding
PGS39_RS19525	COG4839	cell division protein FtsL
PGS39_RS19540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGS39_RS19555	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PGS39_RS19560	COG1399	metal-binding, possibly nucleic acid-binding protein
PGS39_RS19685	COG0740	serine-type endopeptidase activity
PGS39_RS19695	COG1802	Transcriptional regulator
PGS39_RS19695	COG4626	Terminase
PGS39_RS19715	COG0582	viral genome integration into host DNA
PGS39_RS19805	COG1484	DNA-dependent DNA replication
PGS39_RS19835	COG1396	sequence-specific DNA binding
PGS39_RS19880	COG0582	viral genome integration into host DNA
PGS39_RS19890	COG3480	Lon protease (S16) C-terminal proteolytic domain
PGS39_RS19895	COG1752	Esterase of the alpha-beta hydrolase superfamily
PGS39_RS19900	COG3314	Sporulation integral membrane protein YlbJ
PGS39_RS19910	COG0742	ribosomal rna small subunit methyltransferase
PGS39_RS19930	COG3679	Belongs to the UPF0342 family
PGS39_RS19935	COG0406	alpha-ribazole phosphatase activity
PGS39_RS19950	COG2340	Cysteine-rich secretory protein family
PGS39_RS19965	COG3344	reverse transcriptase
PGS39_RS19975	COG3336	cytochrome c oxidase
PGS39_RS19990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGS39_RS20010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PGS39_RS20015	COG0772	Belongs to the SEDS family
PGS39_RS20025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PGS39_RS20030	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PGS39_RS20040	COG4896	Protein conserved in bacteria
PGS39_RS20055	COG1217	gtp-binding protein TYPA
PGS39_RS20065	COG0483	inositol monophosphate 1-phosphatase activity
PGS39_RS20085	COG1982	Orn Lys Arg decarboxylase major
PGS39_RS20130	COG0022	dehydrogenase e1 component
PGS39_RS20135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PGS39_RS20145	COG0242	peptide deformylase activity
PGS39_RS20150	COG0561	phosphatase activity
PGS39_RS20160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGS39_RS20165	COG0569	domain protein
PGS39_RS20185	COG0583	DNA-binding transcription factor activity
PGS39_RS20190	COG0517	IMP dehydrogenase activity
PGS39_RS20200	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
PGS39_RS20210	COG4703	Protein of unknown function (DUF1797)
PGS39_RS20225	COG2200	EAL domain
PGS39_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS20235	COG1408	metallophosphoesterase
PGS39_RS20245	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PGS39_RS20280	COG2814	Major facilitator Superfamily
PGS39_RS20305	COG3209	COG3209 Rhs family protein
PGS39_RS20315	COG2205	protein histidine kinase activity
PGS39_RS20325	COG0436	Aminotransferase
PGS39_RS20330	COG1609	Transcriptional regulator
PGS39_RS20335	COG3833	ABC-type maltose transport systems, permease component
PGS39_RS20340	COG1175	transmembrane transport
PGS39_RS20345	COG2182	Extracellular solute-binding protein
PGS39_RS20355	COG0366	Alpha amylase catalytic
PGS39_RS20360	COG3842	ATPase activity
PGS39_RS20400	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGS39_RS20405	COG0183	Belongs to the thiolase family
PGS39_RS20435	COG1695	Transcriptional regulator
PGS39_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS20465	COG3344	reverse transcriptase
PGS39_RS20470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PGS39_RS20475	COG0436	Aminotransferase
PGS39_RS20510	COG2084	Dehydrogenase
PGS39_RS20520	COG2199	diguanylate cyclase activity
PGS39_RS20525	COG0778	Nitroreductase
PGS39_RS20550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PGS39_RS20550	COG2190	(PTS) system
PGS39_RS20550	COG1263	PTS System
PGS39_RS20555	COG3711	transcriptional antiterminator
PGS39_RS20565	COG2188	Transcriptional regulator
PGS39_RS20575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGS39_RS20600	COG1547	Domain of unknown function (DUF309)
PGS39_RS20605	COG0456	acetyltransferase
PGS39_RS20615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGS39_RS20620	COG4086	secreted protein
PGS39_RS20625	COG0561	phosphatase activity
PGS39_RS20630	COG0697	spore germination
PGS39_RS20645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGS39_RS20670	COG0733	neurotransmitter:sodium symporter activity
PGS39_RS20690	COG1686	Belongs to the peptidase S11 family
PGS39_RS20695	COG1725	Transcriptional regulator
PGS39_RS20700	COG1131	(ABC) transporter
PGS39_RS20715	COG1846	Transcriptional regulator
PGS39_RS20730	COG0598	Magnesium transport protein CorA
PGS39_RS20755	COG4974	Belongs to the 'phage' integrase family
PGS39_RS20765	COG0735	belongs to the Fur family
PGS39_RS20770	COG1300	Membrane
PGS39_RS20790	COG0667	Aldo Keto reductase
PGS39_RS20795	COG0656	L-ascorbic acid biosynthetic process
PGS39_RS20800	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGS39_RS20800	COG0456	acetyltransferase
PGS39_RS20810	COG0737	Belongs to the 5'-nucleotidase family
PGS39_RS20810	COG1525	nuclease
PGS39_RS20810	COG4085	toxin activity
PGS39_RS20820	COG0596	Alpha beta hydrolase
PGS39_RS20825	COG2056	Na+-H+ antiporter family
PGS39_RS20830	COG1609	Transcriptional regulator
PGS39_RS20835	COG0456	acetyltransferase
PGS39_RS20840	COG1073	alpha beta
PGS39_RS20855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGS39_RS20855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGS39_RS20860	COG0307	riboflavin synthase, alpha
PGS39_RS20885	COG4106	trans-aconitate 2-methyltransferase activity
PGS39_RS20890	COG2226	methyltransferase
PGS39_RS20890	COG1073	alpha beta
PGS39_RS20905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PGS39_RS20915	COG1757	Na H antiporter
PGS39_RS20920	COG0737	Belongs to the 5'-nucleotidase family
PGS39_RS20930	COG1522	sequence-specific DNA binding
PGS39_RS20950	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PGS39_RS20975	COG0300	oxidoreductase activity
PGS39_RS20980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS20985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGS39_RS20990	COG1760	l-serine dehydratase
PGS39_RS20995	COG1760	l-serine dehydratase
PGS39_RS21025	COG2195	Cleaves the N-terminal amino acid of tripeptides
PGS39_RS21030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS21045	COG1376	ErfK ybiS ycfS ynhG family protein
PGS39_RS21050	COG4129	membrane
PGS39_RS21055	COG1126	abc transporter atp-binding protein
PGS39_RS21060	COG0765	amino acid transport
PGS39_RS21065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS21080	COG2323	membrane
PGS39_RS21085	COG0772	Belongs to the SEDS family
PGS39_RS21090	COG0508	dehydrogenase complex catalyzes the overall conversion of
PGS39_RS21095	COG0022	dehydrogenase e1 component
PGS39_RS21100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PGS39_RS21105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGS39_RS21120	COG0280	phosphate acetyltransferase
PGS39_RS21125	COG3829	transcription factor binding
PGS39_RS21125	COG3290	protein histidine kinase activity
PGS39_RS21135	COG0584	glycerophosphoryl diester phosphodiesterase
PGS39_RS21140	COG3093	addiction module antidote protein HigA
PGS39_RS21145	COG0745	RESPONSE REGULATOR receiver
PGS39_RS21150	COG0750	zinc metalloprotease
PGS39_RS21155	COG0497	DNA recombination
PGS39_RS21165	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PGS39_RS21175	COG0142	geranyltranstransferase activity
PGS39_RS21200	COG1302	Protein conserved in bacteria
PGS39_RS21205	COG0439	Biotin carboxylase
PGS39_RS21210	COG0511	ligase activity, forming carbon-carbon bonds
PGS39_RS21255	COG3854	ATPases associated with a variety of cellular activities
PGS39_RS21280	COG0006	proline dipeptidase activity
PGS39_RS21295	COG3872	metal-dependent enzyme
PGS39_RS21335	COG0095	Lipoate-protein ligase
PGS39_RS21340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGS39_RS21345	COG1609	Transcriptional regulator
PGS39_RS21355	COG2076	Multidrug Resistance protein
PGS39_RS21360	COG2076	Multidrug Resistance protein
PGS39_RS21395	COG1131	(ABC) transporter
PGS39_RS21400	COG1725	Transcriptional regulator
PGS39_RS21430	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PGS39_RS21620	COG0740	serine-type endopeptidase activity
PGS39_RS21630	COG4626	Terminase
PGS39_RS21630	COG1802	Transcriptional regulator
PGS39_RS21660	COG0582	viral genome integration into host DNA
PGS39_RS21665	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PGS39_RS21815	COG4970	Tfp pilus assembly protein FimT
PGS39_RS21825	COG1459	type II secretion system
PGS39_RS21830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGS39_RS21885	COG0646	methionine synthase
PGS39_RS21885	COG1410	methionine synthase
PGS39_RS21890	COG0646	methionine synthase
PGS39_RS21890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PGS39_RS21895	COG0626	cystathionine gamma-synthase activity
PGS39_RS21900	COG0626	cystathionine gamma-synthase activity
PGS39_RS21920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS21930	COG1940	carbohydrate kinase activity
PGS39_RS21935	COG4483	Protein conserved in bacteria
PGS39_RS21940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGS39_RS21945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PGS39_RS21950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PGS39_RS21955	COG0704	Plays a role in the regulation of phosphate uptake
PGS39_RS21965	COG0581	inorganic phosphate transmembrane transporter activity
PGS39_RS21970	COG0573	inorganic phosphate transmembrane transporter activity
PGS39_RS21975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PGS39_RS21980	COG0768	penicillin binding
PGS39_RS21985	COG0477	Major facilitator Superfamily
PGS39_RS21990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PGS39_RS22015	COG0735	belongs to the Fur family
PGS39_RS22020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PGS39_RS22025	COG1121	(ABC) transporter
PGS39_RS22030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS22060	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGS39_RS22065	COG2384	SAM-dependent methyltransferase
PGS39_RS22070	COG2010	Cytochrome c
PGS39_RS22075	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGS39_RS22080	COG0358	DNA primase activity
PGS39_RS22090	COG0517	IMP dehydrogenase activity
PGS39_RS22105	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGS39_RS22110	COG0295	cytidine deaminase activity
PGS39_RS22115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PGS39_RS22125	COG1480	7TM receptor with intracellular HD hydrolase
PGS39_RS22130	COG1702	phosphate starvation-inducible protein PhoH
PGS39_RS22145	COG1610	YqeY-like protein
PGS39_RS22150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PGS39_RS22155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGS39_RS22160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PGS39_RS22190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PGS39_RS22195	COG1733	regulation of RNA biosynthetic process
PGS39_RS22220	COG1466	dna polymerase III delta subunit
PGS39_RS22230	COG0658	competence protein
PGS39_RS22230	COG2333	competence protein COMEC
PGS39_RS22235	COG2131	deaminase
PGS39_RS22240	COG1555	photosystem II stabilization
PGS39_RS22240	COG1596	polysaccharide export
PGS39_RS22245	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGS39_RS22250	COG2226	methyltransferase
PGS39_RS22255	COG0799	negative regulation of ribosome biogenesis
PGS39_RS22260	COG1713	HD superfamily hydrolase involved in NAD metabolism
PGS39_RS22270	COG1534	Rna-binding protein
PGS39_RS22280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGS39_RS22285	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
PGS39_RS22320	COG2357	RelA SpoT domain protein
PGS39_RS22330	COG1785	Belongs to the alkaline phosphatase family
PGS39_RS22335	COG0456	acetyltransferase
PGS39_RS22340	COG2267	carboxylic ester hydrolase activity
PGS39_RS22375	COG1404	Belongs to the peptidase S8 family
PGS39_RS22380	COG3186	Phenylalanine-4-hydroxylase
PGS39_RS22390	COG2514	catechol 2,3-dioxygenase activity
PGS39_RS22395	COG2259	Doxx family
PGS39_RS22435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
PGS39_RS22445	COG1012	belongs to the aldehyde dehydrogenase family
PGS39_RS22445	COG1454	alcohol dehydrogenase
PGS39_RS22450	COG0626	cystathionine gamma-synthase activity
PGS39_RS22455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PGS39_RS22480	COG0768	penicillin binding
PGS39_RS22495	COG0826	peptidase U32
PGS39_RS22500	COG0826	peptidase U32
PGS39_RS22505	COG4122	O-methyltransferase activity
PGS39_RS22510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGS39_RS22540	COG0628	permease
PGS39_RS22560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PGS39_RS22575	COG1104	cysteine desulfurase activity
PGS39_RS22580	COG1959	2 iron, 2 sulfur cluster binding
PGS39_RS22585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PGS39_RS22595	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PGS39_RS22630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGS39_RS22640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PGS39_RS22640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PGS39_RS22650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGS39_RS22650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGS39_RS22660	COG2244	polysaccharide biosynthetic process
PGS39_RS22665	COG2323	membrane
PGS39_RS22675	COG1862	Preprotein translocase
PGS39_RS22730	COG0157	Belongs to the NadC ModD family
PGS39_RS22735	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
PGS39_RS22740	COG1104	cysteine desulfurase activity
PGS39_RS22745	COG1827	regulation of RNA biosynthetic process
PGS39_RS22750	COG2258	MOSC domain
PGS39_RS22755	COG0077	Prephenate dehydratase
PGS39_RS22760	COG0577	efflux transmembrane transporter activity
PGS39_RS22765	COG0577	efflux transmembrane transporter activity
PGS39_RS22770	COG1136	(ABC) transporter
PGS39_RS22775	COG5002	protein histidine kinase activity
PGS39_RS22780	COG0745	RESPONSE REGULATOR receiver
PGS39_RS22790	COG3290	protein histidine kinase activity
PGS39_RS22800	COG2868	ribosomal protein
PGS39_RS22805	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PGS39_RS22810	COG1530	ribonuclease E activity
PGS39_RS22815	COG1994	Peptidase M50
PGS39_RS22820	COG0739	heme binding
PGS39_RS22825	COG2894	cell division
PGS39_RS22845	COG1077	Cell shape determining protein MreB Mrl
PGS39_RS22865	COG0285	dihydrofolate synthase activity
PGS39_RS22890	COG1388	LysM domain
PGS39_RS22900	COG0113	porphobilinogen synthase activity
PGS39_RS22905	COG1587	Uroporphyrinogen-III synthase
PGS39_RS22915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PGS39_RS22925	COG1846	Transcriptional regulator
PGS39_RS22930	COG1764	response to oxidative stress
PGS39_RS22945	COG0470	DNA polymerase III
PGS39_RS22945	COG1067	ATP-dependent peptidase activity
PGS39_RS23000	COG0622	Phosphoesterase
PGS39_RS23015	COG5401	PFAM Sporulation and spore germination
PGS39_RS23035	COG1309	transcriptional regulator
PGS39_RS23050	COG2197	response regulator
PGS39_RS23055	COG2233	PERMEase
PGS39_RS23060	COG0402	S-adenosylhomocysteine deaminase activity
PGS39_RS23065	COG1983	PspC domain protein
PGS39_RS23070	COG1396	sequence-specific DNA binding
PGS39_RS23075	COG0697	spore germination
PGS39_RS23085	COG1959	2 iron, 2 sulfur cluster binding
PGS39_RS23090	COG1668	transmembrane transport
PGS39_RS23095	COG4152	abc transporter atp-binding protein
PGS39_RS23100	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
PGS39_RS23105	COG1360	Flagellar Motor Protein
PGS39_RS23110	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PGS39_RS23115	COG1876	peptidase activity
PGS39_RS23120	COG0824	Thioesterase
PGS39_RS23125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PGS39_RS23130	COG1053	succinate dehydrogenase
PGS39_RS23135	COG2009	succinate dehydrogenase
PGS39_RS23140	COG1719	4-vinyl reductase, 4VR
PGS39_RS23150	COG3118	belongs to the thioredoxin family
PGS39_RS23155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PGS39_RS23160	COG2086	electron transfer activity
PGS39_RS23165	COG1024	Enoyl-CoA hydratase
PGS39_RS23170	COG1309	transcriptional regulator
PGS39_RS23175	COG0318	PFAM AMP-dependent synthetase and ligase
PGS39_RS23185	COG2318	DinB family
PGS39_RS23210	COG1131	(ABC) transporter
PGS39_RS23215	COG2205	protein histidine kinase activity
PGS39_RS23220	COG0745	RESPONSE REGULATOR receiver
PGS39_RS23230	COG4895	conserved protein (DUF2196)
PGS39_RS23235	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PGS39_RS23250	COG4509	Sortase family
PGS39_RS23255	COG1120	ATPase activity
PGS39_RS23270	COG5386	Cell surface protein
PGS39_RS23275	COG5386	Cell surface protein
PGS39_RS23280	COG1114	Component of the transport system for branched-chain amino acids
PGS39_RS23285	COG1187	pseudouridine synthase activity
PGS39_RS23295	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PGS39_RS23295	COG1796	DNA polymerase
PGS39_RS23300	COG1286	toxin biosynthetic process
PGS39_RS23345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGS39_RS23355	COG1418	mRNA catabolic process
PGS39_RS23365	COG2814	Major facilitator Superfamily
PGS39_RS23370	COG1566	PFAM secretion protein HlyD family protein
PGS39_RS23375	COG1309	transcriptional regulator
PGS39_RS23380	COG1363	Peptidase, m42
PGS39_RS23405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGS39_RS23415	COG1484	DNA-dependent DNA replication
PGS39_RS23420	COG3611	Membrane attachment protein
PGS39_RS23430	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PGS39_RS23435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PGS39_RS23440	COG0237	dephospho-CoA kinase activity
PGS39_RS23445	COG1971	Probably functions as a manganese efflux pump
PGS39_RS23455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGS39_RS23455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGS39_RS23460	COG5002	protein histidine kinase activity
PGS39_RS23465	COG0745	RESPONSE REGULATOR receiver
PGS39_RS23490	COG0538	isocitrate dehydrogenase activity
PGS39_RS23495	COG0372	Belongs to the citrate synthase family
PGS39_RS23505	COG0628	permease
PGS39_RS23510	COG3030	protein affecting phage T7 exclusion by the F plasmid
PGS39_RS23535	COG1725	Transcriptional regulator
PGS39_RS23540	COG0281	malic enzyme
PGS39_RS23545	COG0587	DNA-directed DNA polymerase activity
PGS39_RS23560	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PGS39_RS23585	COG4109	DRTGG domain
PGS39_RS23600	COG0006	proline dipeptidase activity
PGS39_RS23635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS23640	COG0662	Cupin 2, conserved barrel domain protein
PGS39_RS23655	COG1028	Short-chain dehydrogenase reductase Sdr
PGS39_RS23660	COG0589	response to stress
PGS39_RS23730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS23755	COG0827	DNA restriction-modification system
PGS39_RS23760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGS39_RS23765	COG3874	Sporulation protein YtfJ
PGS39_RS23780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PGS39_RS23790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PGS39_RS23805	COG1104	cysteine desulfurase activity
PGS39_RS23815	COG0583	DNA-binding transcription factor activity
PGS39_RS23820	COG0697	spore germination
PGS39_RS23825	COG1309	transcriptional regulator
PGS39_RS23830	COG1956	GAF domain-containing protein
PGS39_RS23835	COG0626	cystathionine gamma-synthase activity
PGS39_RS23865	COG1595	DNA-templated transcription, initiation
PGS39_RS23875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PGS39_RS23880	COG0454	-acetyltransferase
PGS39_RS23885	COG0517	IMP dehydrogenase activity
PGS39_RS23890	COG0123	including yeast histone deacetylase and acetoin utilization protein
PGS39_RS23905	COG0745	RESPONSE REGULATOR receiver
PGS39_RS23945	COG1609	Transcriptional regulator
PGS39_RS23950	COG4851	CamS sex pheromone cAM373 precursor
PGS39_RS23955	COG3118	belongs to the thioredoxin family
PGS39_RS23965	COG2309	aminopeptidase activity
PGS39_RS23985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS24000	COG1674	ftsk spoiiie
PGS39_RS24010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGS39_RS24020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS24025	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
PGS39_RS24030	COG1363	Peptidase, m42
PGS39_RS24040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS24055	COG0510	thiamine kinase activity
PGS39_RS24060	COG1523	belongs to the glycosyl hydrolase 13 family
PGS39_RS24070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PGS39_RS24075	COG1349	DNA-binding transcription factor activity
PGS39_RS24080	COG1187	pseudouridine synthase activity
PGS39_RS24085	COG2244	polysaccharide biosynthetic process
PGS39_RS24090	COG2081	HI0933 family
PGS39_RS24095	COG2814	Major facilitator Superfamily
PGS39_RS24105	COG3832	glyoxalase III activity
PGS39_RS24125	COG1329	Transcriptional regulator
PGS39_RS24150	COG0314	molybdopterin synthase activity
PGS39_RS24155	COG1763	Mo-molybdopterin cofactor biosynthetic process
PGS39_RS24160	COG0303	'Molybdopterin
PGS39_RS24170	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PGS39_RS24175	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGS39_RS24195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGS39_RS24205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGS39_RS24245	COG2814	Major facilitator Superfamily
PGS39_RS24250	COG0475	glutathione-regulated potassium exporter activity
PGS39_RS24255	COG0490	domain, Protein
PGS39_RS24260	COG0582	viral genome integration into host DNA
PGS39_RS24270	COG1136	(ABC) transporter
PGS39_RS24290	COG1242	4 iron, 4 sulfur cluster binding
PGS39_RS24295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PGS39_RS24310	COG1794	racemase activity, acting on amino acids and derivatives
PGS39_RS24335	COG2267	carboxylic ester hydrolase activity
PGS39_RS24340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PGS39_RS24345	COG0671	phosphoesterase, PA-phosphatase related
PGS39_RS24350	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS24360	COG0521	Mo-molybdopterin cofactor biosynthetic process
PGS39_RS24375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS24430	COG5002	protein histidine kinase activity
PGS39_RS24435	COG4191	Histidine kinase
PGS39_RS24440	COG2267	carboxylic ester hydrolase activity
PGS39_RS24445	COG1368	sulfuric ester hydrolase activity
PGS39_RS24465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PGS39_RS24470	COG1116	anion transmembrane transporter activity
PGS39_RS24475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PGS39_RS24500	COG0494	nUDIX hydrolase
PGS39_RS24535	COG0288	reversible hydration of carbon dioxide
PGS39_RS24540	COG1271	oxidase subunit
PGS39_RS24545	COG1294	oxidase, subunit
PGS39_RS24565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS24590	COG1842	Phage shock protein A
PGS39_RS24625	COG5002	protein histidine kinase activity
PGS39_RS24630	COG0745	RESPONSE REGULATOR receiver
PGS39_RS24660	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PGS39_RS24665	COG1597	lipid kinase activity
PGS39_RS24685	COG0577	efflux transmembrane transporter activity
PGS39_RS24690	COG1136	(ABC) transporter
PGS39_RS24705	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS24715	COG4977	sequence-specific DNA binding
PGS39_RS24725	COG0577	efflux transmembrane transporter activity
PGS39_RS24730	COG1136	(ABC) transporter
PGS39_RS24735	COG2207	Transcriptional regulator
PGS39_RS24735	COG3708	Transcriptional regulator
PGS39_RS24740	COG5658	integral membrane protein
PGS39_RS24745	COG0640	Transcriptional regulator
PGS39_RS24750	COG0745	RESPONSE REGULATOR receiver
PGS39_RS24755	COG2205	protein histidine kinase activity
PGS39_RS24760	COG0577	efflux transmembrane transporter activity
PGS39_RS24765	COG0577	efflux transmembrane transporter activity
PGS39_RS24770	COG1136	(ABC) transporter
PGS39_RS24775	COG0577	efflux transmembrane transporter activity
PGS39_RS24790	COG2188	Transcriptional regulator
PGS39_RS24810	COG3964	amidohydrolase
PGS39_RS24830	COG4948	Mandelate Racemase Muconate Lactonizing
PGS39_RS24840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGS39_RS24845	COG0596	Alpha beta hydrolase
PGS39_RS24855	COG1169	isochorismate synthase
PGS39_RS24860	COG1575	Belongs to the MenA family. Type 1 subfamily
PGS39_RS24865	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PGS39_RS24895	COG0058	SHG alpha-glucan phosphorylase activity
PGS39_RS24905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PGS39_RS24925	COG1404	Belongs to the peptidase S8 family
PGS39_RS25025	COG0544	peptidyl-prolyl cis-trans isomerase activity
PGS39_RS25060	COG1285	pathogenesis
PGS39_RS25065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PGS39_RS25080	COG2155	Conserved Protein
PGS39_RS25085	COG1098	S1 RNA binding domain
PGS39_RS25090	COG0436	Aminotransferase
PGS39_RS25095	COG1522	sequence-specific DNA binding
PGS39_RS25100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGS39_RS25105	COG2267	carboxylic ester hydrolase activity
PGS39_RS25115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PGS39_RS25135	COG5018	Exonuclease
PGS39_RS25140	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGS39_RS25160	COG2050	protein possibly involved in aromatic compounds catabolism
PGS39_RS25170	COG1268	BioY protein
PGS39_RS25180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PGS39_RS25185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGS39_RS25200	COG3584	3D domain protein
PGS39_RS25215	COG1252	NADH dehydrogenase
PGS39_RS25225	COG3708	Transcriptional regulator
PGS39_RS25240	COG1683	Conserved Protein
PGS39_RS25255	COG0316	Belongs to the HesB IscA family
PGS39_RS25270	COG1252	NADH dehydrogenase
PGS39_RS25280	COG2274	protein secretion by the type I secretion system
PGS39_RS25285	COG0390	transport system, permease component
PGS39_RS25290	COG2824	Alkylphosphonate utilization operon protein PhnA
PGS39_RS25330	COG4837	Protein of unknown function (DUF1462)
PGS39_RS25335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PGS39_RS25345	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PGS39_RS25350	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PGS39_RS25360	COG2249	NAD(P)H dehydrogenase (quinone) activity
PGS39_RS25365	COG0647	UMP catabolic process
PGS39_RS25375	COG2445	Protein of unknown function DUF86
PGS39_RS25380	COG1494	fructose-1,6-bisphosphatase
PGS39_RS25395	COG4470	Protein conserved in bacteria
PGS39_RS25405	COG0789	Transcriptional regulator
PGS39_RS25410	COG4377	Putative membrane peptidase family (DUF2324)
PGS39_RS25435	COG0739	heme binding
PGS39_RS25445	COG3377	Domain of unknown function (DUF1805)
PGS39_RS25450	COG0737	Belongs to the 5'-nucleotidase family
PGS39_RS25455	COG0719	Fe-S assembly protein
PGS39_RS25460	COG0822	iron-sulfur transferase activity
PGS39_RS25465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGS39_RS25470	COG0719	Fe-S assembly protein
PGS39_RS25475	COG0396	ATPase activity
PGS39_RS25480	COG1464	Belongs to the NlpA lipoprotein family
PGS39_RS25485	COG1464	Belongs to the NlpA lipoprotein family
PGS39_RS25490	COG2011	ABC-type metal ion transport system permease component
PGS39_RS25495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGS39_RS25505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS25510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGS39_RS25520	COG1393	Belongs to the ArsC family
PGS39_RS25575	COG1396	sequence-specific DNA binding
PGS39_RS25585	COG1309	transcriptional regulator
PGS39_RS25590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PGS39_RS25595	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS25605	COG0183	Belongs to the thiolase family
PGS39_RS25610	COG1024	Enoyl-CoA hydratase
PGS39_RS25610	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGS39_RS25620	COG1686	Belongs to the peptidase S11 family
PGS39_RS25635	COG0011	TIGRFAM Protein of
PGS39_RS25640	COG0840	transmembrane signaling receptor activity
PGS39_RS25670	COG2814	Major facilitator Superfamily
PGS39_RS25675	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PGS39_RS25685	COG0531	amino acid
PGS39_RS25720	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGS39_RS25755	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS25765	COG1376	ErfK ybiS ycfS ynhG family protein
PGS39_RS25770	COG0745	RESPONSE REGULATOR receiver
PGS39_RS25775	COG5002	protein histidine kinase activity
PGS39_RS25805	COG0840	transmembrane signaling receptor activity
PGS39_RS25810	COG2151	metal-sulfur cluster biosynthetic enzyme
PGS39_RS25815	COG3227	Zinc metalloprotease (Elastase)
PGS39_RS25820	COG1741	Belongs to the pirin family
PGS39_RS25835	COG0475	glutathione-regulated potassium exporter activity
PGS39_RS25840	COG0490	domain, Protein
PGS39_RS25845	COG1115	amino acid carrier protein
PGS39_RS25850	COG0783	Belongs to the Dps family
PGS39_RS25870	COG1611	Belongs to the LOG family
PGS39_RS25890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS25895	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS25900	COG1115	amino acid carrier protein
PGS39_RS25905	COG1115	amino acid carrier protein
PGS39_RS25910	COG2910	NAD(P)H-binding
PGS39_RS25930	COG0656	L-ascorbic acid biosynthetic process
PGS39_RS25935	COG2814	Major facilitator Superfamily
PGS39_RS25940	COG1733	regulation of RNA biosynthetic process
PGS39_RS25950	COG1252	NADH dehydrogenase
PGS39_RS25955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGS39_RS25985	COG3290	protein histidine kinase activity
PGS39_RS25985	COG0840	transmembrane signaling receptor activity
PGS39_RS25995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGS39_RS26020	COG0488	(ABC) transporter
PGS39_RS26025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGS39_RS26070	COG1136	(ABC) transporter
PGS39_RS26090	COG0586	Pfam SNARE associated Golgi protein
PGS39_RS26095	COG3963	phosphatidate phosphatase activity
PGS39_RS26145	COG2207	Transcriptional regulator
PGS39_RS26145	COG3708	Transcriptional regulator
PGS39_RS26160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGS39_RS26165	COG2814	Major facilitator Superfamily
PGS39_RS26175	COG0640	Transcriptional regulator
PGS39_RS26180	COG2311	Membrane
PGS39_RS26200	COG0557	exoribonuclease II activity
PGS39_RS26205	COG1647	Serine aminopeptidase, S33
PGS39_RS26210	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PGS39_RS26215	COG1346	cytolysis
PGS39_RS26250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PGS39_RS26265	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PGS39_RS26290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGS39_RS26305	COG2323	membrane
PGS39_RS26315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PGS39_RS26325	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PGS39_RS26335	COG1051	belongs to the nudix hydrolase family
PGS39_RS26345	COG0492	ferredoxin-NADP+ reductase activity
PGS39_RS26350	COG0457	Tetratricopeptide repeat
PGS39_RS26355	COG0110	maltose O-acetyltransferase activity
PGS39_RS26375	COG1950	PFAM Membrane protein of
PGS39_RS26385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PGS39_RS26400	COG0789	Transcriptional regulator
PGS39_RS26435	COG0583	DNA-binding transcription factor activity
PGS39_RS26445	COG0655	NAD(P)H dehydrogenase (quinone) activity
PGS39_RS26460	COG1132	(ABC) transporter
PGS39_RS26465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGS39_RS26470	COG3409	Peptidoglycan-binding domain 1 protein
PGS39_RS26470	COG0793	Belongs to the peptidase S41A family
PGS39_RS26475	COG2177	Part of the ABC transporter FtsEX involved in
PGS39_RS26480	COG2884	Cell division ATP-binding protein ftsE
PGS39_RS26500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGS39_RS26505	COG1278	Cold shock
PGS39_RS26510	COG1040	competence protein
PGS39_RS26515	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PGS39_RS26520	COG1388	LysM domain
PGS39_RS26520	COG0791	NLP P60 protein
PGS39_RS26525	COG1733	regulation of RNA biosynthetic process
PGS39_RS26530	COG1307	EDD domain protein, DegV family
PGS39_RS26535	COG1739	Uncharacterized protein family UPF0029
PGS39_RS26540	COG1316	TRANSCRIPTIONal
PGS39_RS26545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
PGS39_RS26550	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PGS39_RS26555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGS39_RS26565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
PGS39_RS26565	COG3933	PFAM sigma-54 factor interaction domain-containing protein
PGS39_RS26585	COG1486	melibiose metabolic process
PGS39_RS26590	COG1447	Phosphotransferase system cellobiose-specific component IIA
PGS39_RS26595	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PGS39_RS26605	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PGS39_RS26625	COG1447	Phosphotransferase system cellobiose-specific component IIA
PGS39_RS26635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PGS39_RS26640	COG1301	dicarboxylic acid transport
PGS39_RS26650	COG0346	lactoylglutathione lyase activity
PGS39_RS26675	COG0583	DNA-binding transcription factor activity
PGS39_RS26680	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
PGS39_RS26690	COG1271	oxidase subunit
PGS39_RS26695	COG1294	oxidase, subunit
PGS39_RS26700	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGS39_RS26710	COG1620	l-lactate permease
PGS39_RS26720	COG2389	metal-binding protein
PGS39_RS26730	COG1368	sulfuric ester hydrolase activity
PGS39_RS26740	COG0791	NLP P60 protein
PGS39_RS26740	COG1388	LysM domain
PGS39_RS26745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGS39_RS26765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PGS39_RS26770	COG3584	3D domain protein
PGS39_RS26770	COG1388	LysM domain
PGS39_RS26795	COG4715	Zinc finger, swim domain protein
PGS39_RS26800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PGS39_RS26840	COG0577	efflux transmembrane transporter activity
PGS39_RS26845	COG1136	(ABC) transporter
PGS39_RS26870	COG3850	Histidine kinase
PGS39_RS26870	COG5002	protein histidine kinase activity
PGS39_RS26875	COG0745	RESPONSE REGULATOR receiver
PGS39_RS26880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PGS39_RS26890	COG1316	TRANSCRIPTIONal
PGS39_RS26895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PGS39_RS26900	COG1216	Glycosyl transferase, family 2
PGS39_RS26910	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS26930	COG1086	Polysaccharide biosynthesis protein
PGS39_RS26945	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PGS39_RS26950	COG1086	Polysaccharide biosynthesis protein
PGS39_RS26955	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PGS39_RS26960	COG4464	protein tyrosine phosphatase activity
PGS39_RS26965	COG0489	protein tyrosine kinase activity
PGS39_RS26970	COG3944	biosynthesis protein
PGS39_RS26975	COG0489	protein tyrosine kinase activity
PGS39_RS26990	COG1609	Transcriptional regulator
PGS39_RS27000	COG0739	heme binding
PGS39_RS27015	COG3279	Response regulator of the LytR AlgR family
PGS39_RS27020	COG2385	sporulation resulting in formation of a cellular spore
PGS39_RS27035	COG4836	Membrane
PGS39_RS27040	COG1007	ATP synthesis coupled electron transport
PGS39_RS27045	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PGS39_RS27050	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PGS39_RS27060	COG0839	Belongs to the complex I subunit 6 family
PGS39_RS27080	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PGS39_RS27095	COG5001	Diguanylate cyclase
PGS39_RS27095	COG3300	MHYT domain
PGS39_RS27145	COG0356	it plays a direct role in the translocation of protons across the membrane
PGS39_RS27180	COG0698	ribose 5-phosphate isomerase
PGS39_RS27190	COG2190	(PTS) system
PGS39_RS27195	COG2259	Doxx family
PGS39_RS27200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGS39_RS27215	COG0009	L-threonylcarbamoyladenylate synthase
PGS39_RS27230	COG2890	protein-(glutamine-N5) methyltransferase activity
PGS39_RS27250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PGS39_RS27255	COG1494	fructose-1,6-bisphosphatase
PGS39_RS27275	COG4821	SIS domain
PGS39_RS27295	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS27300	COG1960	acyl-CoA dehydrogenase activity
PGS39_RS27305	COG1250	3-hydroxyacyl-CoA dehydrogenase
PGS39_RS27310	COG0183	Belongs to the thiolase family
PGS39_RS27315	COG0247	lactate metabolic process
PGS39_RS27315	COG2181	nitrate reductase activity
PGS39_RS27320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS27330	COG3300	MHYT domain
PGS39_RS27330	COG5001	Diguanylate cyclase
PGS39_RS27350	COG2197	response regulator
PGS39_RS27355	COG4585	Histidine kinase
PGS39_RS27360	COG0842	Transport permease protein
PGS39_RS27365	COG1131	(ABC) transporter
PGS39_RS27370	COG0024	Methionine aminopeptidase
PGS39_RS27380	COG2234	aminopeptidase activity
PGS39_RS27400	COG1595	DNA-templated transcription, initiation
PGS39_RS27410	COG4506	Protein conserved in bacteria
PGS39_RS27415	COG1619	proteins homologs of microcin C7 resistance protein MccF
PGS39_RS27440	COG2814	Major facilitator Superfamily
PGS39_RS27445	COG0789	Transcriptional regulator
PGS39_RS27450	COG0584	glycerophosphoryl diester phosphodiesterase
PGS39_RS27455	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PGS39_RS27465	COG1994	Peptidase M50
PGS39_RS27475	COG1078	dGTPase activity
PGS39_RS27480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PGS39_RS27485	COG1120	ATPase activity
PGS39_RS27490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS27495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGS39_RS27515	COG0095	Lipoate-protein ligase
PGS39_RS27520	COG0280	phosphate acetyltransferase
PGS39_RS27535	COG3773	Cell wall hydrolase
PGS39_RS27545	COG2363	Small membrane protein
PGS39_RS27555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PGS39_RS27560	COG2233	PERMEase
PGS39_RS27565	COG0561	phosphatase activity
PGS39_RS27570	COG2814	Major facilitator Superfamily
PGS39_RS27580	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PGS39_RS27585	COG1131	(ABC) transporter
PGS39_RS27590	COG2755	lipolytic protein G-D-S-L family
PGS39_RS27595	COG1609	Transcriptional regulator
PGS39_RS27605	COG0460	homoserine dehydrogenase
PGS39_RS27615	COG2873	o-acetylhomoserine
PGS39_RS27625	COG1011	Hydrolase
PGS39_RS27630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PGS39_RS27640	COG2197	response regulator
PGS39_RS27645	COG2203	Gaf domain
PGS39_RS27645	COG4585	Histidine kinase
PGS39_RS27650	COG0351	phosphomethylpyrimidine kinase
PGS39_RS27655	COG3706	GGDEF domain
PGS39_RS27660	COG2879	small protein
PGS39_RS27665	COG1966	Carbon starvation protein
PGS39_RS27670	COG3279	Response regulator of the LytR AlgR family
PGS39_RS27675	COG0477	Major facilitator Superfamily
PGS39_RS27685	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS27700	COG0840	transmembrane signaling receptor activity
PGS39_RS27710	COG1607	acyl-coa hydrolase
PGS39_RS27715	COG1216	Glycosyl transferase, family 2
PGS39_RS27730	COG1216	Glycosyl transferase, family 2
PGS39_RS27745	COG0488	(ABC) transporter
PGS39_RS27750	COG1309	transcriptional regulator
PGS39_RS27755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGS39_RS27760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGS39_RS27760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGS39_RS27765	COG0628	permease
PGS39_RS27780	COG3279	Response regulator of the LytR AlgR family
PGS39_RS27785	COG3275	phosphorelay sensor kinase activity
PGS39_RS27790	COG2814	Major facilitator Superfamily
PGS39_RS27795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PGS39_RS27800	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PGS39_RS27805	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PGS39_RS27850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PGS39_RS27855	COG1272	protein, Hemolysin III
PGS39_RS27875	COG1164	Oligoendopeptidase f
PGS39_RS27895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGS39_RS27900	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PGS39_RS27905	COG4853	Protein conserved in bacteria
PGS39_RS27910	COG4863	YycH protein
PGS39_RS27915	COG5002	protein histidine kinase activity
PGS39_RS27920	COG0745	RESPONSE REGULATOR receiver
PGS39_RS27950	COG0305	Participates in initiation and elongation during chromosome replication
PGS39_RS27960	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
PGS39_RS27965	COG4241	membrane
PGS39_RS27975	COG0629	single-stranded DNA binding
PGS39_RS27985	COG0012	GTP binding
PGS39_RS27990	COG4481	Protein conserved in bacteria
PGS39_RS27995	COG0668	transmembrane transport
PGS39_RS28005	COG1475	DNA binding
PGS39_RS28010	COG1192	Involved in chromosome partitioning
PGS39_RS28035	COG1847	R3H domain protein
PGS39_RS28040	COG0706	membrane insertase activity
PGS39_RS28050	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PGS39_RS28095	COG3655	Transcriptional regulator
PGS39_RS28130	COG3177	Filamentation induced by cAMP protein fic
PGS39_RS28140	COG1940	carbohydrate kinase activity
PGS39_RS28145	COG2723	6-phospho-beta-galactosidase activity
PGS39_RS28150	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PGS39_RS28150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PGS39_RS28155	COG1447	Phosphotransferase system cellobiose-specific component IIA
PGS39_RS28160	COG1349	DNA-binding transcription factor activity
PGS39_RS28170	COG0698	ribose 5-phosphate isomerase
PGS39_RS28180	COG3684	Belongs to the aldolase LacD family
PGS39_RS28185	COG0561	phosphatase activity
PGS39_RS28220	COG2323	membrane
PGS39_RS28230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGS39_RS28235	COG2323	membrane
PGS39_RS28260	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGS39_RS28275	COG2323	membrane
PGS39_RS28300	COG0697	spore germination
PGS39_RS28360	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
PGS39_RS28360	COG0778	Nitroreductase
PGS39_RS28370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGS39_RS28410	COG4974	Belongs to the 'phage' integrase family
PGS39_RS28480	COG0148	phosphopyruvate hydratase activity
PGS39_RS28495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGS39_RS28595	COG4585	Histidine kinase
PGS39_RS28600	COG2197	response regulator
PGS39_RS28645	COG4974	Belongs to the 'phage' integrase family
PGS39_RS28660	COG0457	Tetratricopeptide repeat
PGS39_RS28695	COG1181	Belongs to the D-alanine--D-alanine ligase family
PGS39_RS28695	COG2918	glutathione biosynthetic process
PGS39_RS28705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PGS39_RS28715	COG1733	regulation of RNA biosynthetic process
PGS39_RS28720	COG0604	alcohol dehydrogenase
PGS39_RS28795	COG1476	TRANSCRIPTIONal
PGS39_RS28810	COG3013	Belongs to the UPF0304 family
PGS39_RS28830	COG3344	reverse transcriptase
PGS39_RS28850	COG1733	regulation of RNA biosynthetic process
PGS39_RS28875	COG0697	spore germination
PGS39_RS28945	COG3344	reverse transcriptase
PGS39_RS28965	COG3344	reverse transcriptase
PGS39_RS29055	COG3344	reverse transcriptase
PGS39_RS29185	COG3344	reverse transcriptase
PGS39_RS29410	COG3344	reverse transcriptase
PGS39_RS29470	COG2311	Membrane
PGS39_RS29510	COG0546	phosphoglycolate phosphatase activity
PGS39_RS29515	COG4644	lycopene metabolic process
PGS39_RS29535	COG3708	Transcriptional regulator
PGS39_RS29535	COG2207	Transcriptional regulator
PGS39_RS29625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGS39_RS29635	COG0210	DNA helicase
PGS39_RS29640	COG0470	DNA polymerase III
PGS39_RS29655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGS39_RS29660	COG2304	oxidoreductase activity
PGS39_RS29665	COG2002	toxin-antitoxin pair type II binding
PGS39_RS29710	COG0457	Tetratricopeptide repeat
PGS39_RS29720	COG1988	membrane-bound metal-dependent
PGS39_RS29745	COG1525	nuclease
PGS39_RS29805	COG0798	PFAM Bile acid sodium symporter
PGS39_RS29810	COG0640	Transcriptional regulator
PGS39_RS29830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PGS39_RS29840	COG3620	sequence-specific DNA binding
PGS39_RS29845	COG0306	phosphate transporter
PGS39_RS29850	COG0640	Transcriptional regulator
PGS39_RS29865	COG1846	Transcriptional regulator
PGS39_RS29905	COG2217	Heavy metal translocating P-type atpase
PGS39_RS29910	COG1937	Protein conserved in bacteria
PGS39_RS29915	COG3443	Belongs to the bacterial solute-binding protein 9 family
PGS39_RS29915	COG0803	Belongs to the bacterial solute-binding protein 9 family
PGS39_RS29940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PGS39_RS29985	COG3118	belongs to the thioredoxin family
PGS39_RS29995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PGS39_RS30000	COG0765	amino acid transport
PGS39_RS30005	COG1126	abc transporter atp-binding protein
PGS39_RS30010	COG2304	oxidoreductase activity
PGS39_RS30015	COG2132	Multicopper oxidase
PGS39_RS30020	COG0745	RESPONSE REGULATOR receiver
PGS39_RS30025	COG5002	protein histidine kinase activity
PGS39_RS30035	COG0860	N-Acetylmuramoyl-L-alanine amidase
PGS39_RS30055	COG5002	protein histidine kinase activity
PGS39_RS30060	COG0745	RESPONSE REGULATOR receiver
PGS39_RS30065	COG4990	cell redox homeostasis
PGS39_RS30070	COG1335	isochorismatase
PGS39_RS30100	COG0546	phosphoglycolate phosphatase activity
PGS39_RS30145	COG3344	reverse transcriptase
PGS39_RS30170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PGS39_RS30220	COG1780	Probably involved in ribonucleotide reductase function
PGS39_RS30380	COG1466	dna polymerase III delta subunit
PGS39_RS30390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGS39_RS30405	COG3344	reverse transcriptase
PGS39_RS30435	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGS39_RS30525	COG3344	reverse transcriptase
PGS39_RS30545	COG0741	lytic transglycosylase activity
PGS39_RS30545	COG0791	NLP P60 protein
PGS39_RS30585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGS39_RS30680	COG0540	Belongs to the ATCase OTCase family
PGS39_RS30730	COG2226	methyltransferase
PGS39_RS30740	COG0167	dihydroorotate dehydrogenase activity
PGS39_RS30745	COG3238	Protein conserved in bacteria
PGS39_RS30750	COG1611	Belongs to the LOG family
PGS39_RS30760	COG2368	4-hydroxyphenylacetate
PGS39_RS30765	COG0494	nUDIX hydrolase
PGS39_RS30780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGS39_RS31080	COG1476	TRANSCRIPTIONal
PGS39_RS31085	COG2197	response regulator
PGS39_RS31090	COG4191	Histidine kinase
PGS39_RS31095	COG1073	alpha beta
PGS39_RS31155	COG0438	transferase activity, transferring glycosyl groups
PGS39_RS31175	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PGS39_RS31210	COG0457	Tetratricopeptide repeat
PGS39_RS31260	COG3209	COG3209 Rhs family protein
PGS39_RS31275	COG2003	Belongs to the UPF0758 family
PGS39_RS31295	COG0270	DNA (cytosine-5-)-methyltransferase activity