locus-tag	class	description
MA06_RS00135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MA06_RS00150	COG4290	ribonuclease
MA06_RS00155	COG2732	(Barnase) inhibitor
MA06_RS00165	COG1131	(ABC) transporter
MA06_RS00205	COG0668	transmembrane transport
MA06_RS00225	COG1131	(ABC) transporter
MA06_RS00230	COG0745	RESPONSE REGULATOR receiver
MA06_RS00235	COG5002	protein histidine kinase activity
MA06_RS00235	COG3850	Histidine kinase
MA06_RS00255	COG3344	reverse transcriptase
MA06_RS00290	COG1819	glycosyl
MA06_RS00300	COG2801	Transposase and inactivated derivatives
MA06_RS00315	COG0739	heme binding
MA06_RS00320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MA06_RS00325	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MA06_RS00355	COG1073	alpha beta
MA06_RS00485	COG0604	alcohol dehydrogenase
MA06_RS00495	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MA06_RS00595	COG1192	Involved in chromosome partitioning
MA06_RS00630	COG5504	Zn-dependent protease
MA06_RS00660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MA06_RS00700	COG1619	proteins homologs of microcin C7 resistance protein MccF
MA06_RS00710	COG0137	argininosuccinate synthase activity
MA06_RS00725	COG2002	toxin-antitoxin pair type II binding
MA06_RS00755	COG2226	methyltransferase
MA06_RS00820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MA06_RS00845	COG1396	sequence-specific DNA binding
MA06_RS00855	COG3617	BRO family, N-terminal domain
MA06_RS00875	COG1484	DNA-dependent DNA replication
MA06_RS00890	COG0741	lytic transglycosylase activity
MA06_RS00900	COG0741	lytic transglycosylase activity
MA06_RS00900	COG0739	heme binding
MA06_RS00900	COG1196	nuclear chromosome segregation
MA06_RS00905	COG4824	toxin secretion phage lysis holin
MA06_RS00975	COG0582	viral genome integration into host DNA
MA06_RS00980	COG1280	lysine exporter protein (LysE YggA)
MA06_RS00985	COG3403	YqcI/YcgG family
MA06_RS01020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MA06_RS01030	COG1309	transcriptional regulator
MA06_RS01045	COG1533	DNA photolyase activity
MA06_RS01105	COG2814	Major facilitator Superfamily
MA06_RS01130	COG2801	Transposase and inactivated derivatives
MA06_RS01140	COG1329	Transcriptional regulator
MA06_RS01165	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS01175	COG3781	membrane
MA06_RS01185	COG0789	Transcriptional regulator
MA06_RS01185	COG4978	Transcriptional regulator
MA06_RS01240	COG2124	cytochrome p450
MA06_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS01305	COG2801	Transposase and inactivated derivatives
MA06_RS01385	COG1136	(ABC) transporter
MA06_RS01390	COG2084	Dehydrogenase
MA06_RS01395	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MA06_RS01405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MA06_RS01415	COG1309	transcriptional regulator
MA06_RS01420	COG2814	Major facilitator Superfamily
MA06_RS01425	COG1846	Transcriptional regulator
MA06_RS01430	COG0583	DNA-binding transcription factor activity
MA06_RS01455	COG1335	isochorismatase
MA06_RS01460	COG2267	carboxylic ester hydrolase activity
MA06_RS01500	COG4851	CamS sex pheromone cAM373 precursor
MA06_RS01595	COG0738	Major facilitator superfamily
MA06_RS01600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MA06_RS01610	COG1063	alcohol dehydrogenase
MA06_RS01630	COG1760	l-serine dehydratase
MA06_RS01640	COG0156	8-amino-7-oxononanoate synthase activity
MA06_RS01675	COG1115	amino acid carrier protein
MA06_RS01685	COG4191	Histidine kinase
MA06_RS01690	COG0784	Response regulator, receiver
MA06_RS01705	COG1024	Enoyl-CoA hydratase
MA06_RS01725	COG2801	Transposase and inactivated derivatives
MA06_RS02025	COG1396	sequence-specific DNA binding
MA06_RS02080	COG1923	regulation of RNA biosynthetic process
MA06_RS02090	COG2002	toxin-antitoxin pair type II binding
MA06_RS02110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MA06_RS02170	COG0791	NLP P60 protein
MA06_RS02170	COG3883	PFAM NLP P60 protein
MA06_RS02175	COG3344	reverse transcriptase
MA06_RS02190	COG1131	(ABC) transporter
MA06_RS02225	COG0628	permease
MA06_RS02255	COG2746	aminoglycoside 3-N-acetyltransferase activity
MA06_RS02275	COG0697	spore germination
MA06_RS02280	COG2318	DinB family
MA06_RS02285	COG0596	Alpha beta hydrolase
MA06_RS02325	COG1368	sulfuric ester hydrolase activity
MA06_RS02330	COG0488	(ABC) transporter
MA06_RS02345	COG0287	Prephenate dehydrogenase
MA06_RS02360	COG1605	Chorismate mutase
MA06_RS02360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MA06_RS02375	COG3048	D-serine ammonia-lyase activity
MA06_RS02415	COG0346	lactoylglutathione lyase activity
MA06_RS02435	COG1476	TRANSCRIPTIONal
MA06_RS02440	COG0346	lactoylglutathione lyase activity
MA06_RS02445	COG0477	Major facilitator Superfamily
MA06_RS02465	COG1879	ABC-type sugar transport system periplasmic component
MA06_RS02470	COG1172	Belongs to the binding-protein-dependent transport system permease family
MA06_RS02475	COG1172	Belongs to the binding-protein-dependent transport system permease family
MA06_RS02485	COG2390	Transcriptional regulator
MA06_RS02490	COG1070	Carbohydrate kinase
MA06_RS02505	COG0768	penicillin binding
MA06_RS02510	COG0768	penicillin binding
MA06_RS02530	COG1595	DNA-templated transcription, initiation
MA06_RS02535	COG2329	Antibiotic biosynthesis monooxygenase
MA06_RS02540	COG2814	Major facilitator Superfamily
MA06_RS02560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS02565	COG0346	lactoylglutathione lyase activity
MA06_RS02595	COG0714	Associated with various cellular activities
MA06_RS02615	COG0778	Nitroreductase
MA06_RS02620	COG1846	Transcriptional regulator
MA06_RS02640	COG0494	nUDIX hydrolase
MA06_RS02670	COG0456	acetyltransferase
MA06_RS02680	COG0477	Major facilitator Superfamily
MA06_RS02690	COG1011	Hydrolase
MA06_RS02700	COG3655	Transcriptional regulator
MA06_RS02730	COG0697	spore germination
MA06_RS02735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS02740	COG0697	spore germination
MA06_RS02760	COG0730	response to heat
MA06_RS02765	COG0833	amino acid
MA06_RS02780	COG1335	isochorismatase
MA06_RS02785	COG1183	phosphatidylcholine synthase activity
MA06_RS02815	COG0693	protein deglycase activity
MA06_RS02840	COG0768	penicillin binding
MA06_RS02850	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MA06_RS02865	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MA06_RS02870	COG1984	allophanate hydrolase subunit 2
MA06_RS02875	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MA06_RS02880	COG1414	Transcriptional regulator
MA06_RS02895	COG0739	heme binding
MA06_RS02905	COG2011	ABC-type metal ion transport system permease component
MA06_RS02910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MA06_RS02915	COG1960	acyl-CoA dehydrogenase activity
MA06_RS02920	COG1464	Belongs to the NlpA lipoprotein family
MA06_RS02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS02960	COG0346	lactoylglutathione lyase activity
MA06_RS02970	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MA06_RS02990	COG1136	(ABC) transporter
MA06_RS02995	COG0577	efflux transmembrane transporter activity
MA06_RS03000	COG3279	Response regulator of the LytR AlgR family
MA06_RS03010	COG0577	efflux transmembrane transporter activity
MA06_RS03015	COG1136	(ABC) transporter
MA06_RS03030	COG0596	Alpha beta hydrolase
MA06_RS03035	COG3850	Histidine kinase
MA06_RS03035	COG5002	protein histidine kinase activity
MA06_RS03055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MA06_RS03075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MA06_RS03170	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS03210	COG1523	belongs to the glycosyl hydrolase 13 family
MA06_RS03255	COG0596	Alpha beta hydrolase
MA06_RS03335	COG3552	Protein containing von Willebrand factor type A (VWA) domain
MA06_RS03345	COG0714	Associated with various cellular activities
MA06_RS03375	COG2132	Multicopper oxidase
MA06_RS03380	COG0006	proline dipeptidase activity
MA06_RS03430	COG1397	ADP-ribosylglycohydrolase
MA06_RS03540	COG1397	ADP-ribosylglycohydrolase
MA06_RS03595	COG0477	Major facilitator Superfamily
MA06_RS03610	COG1846	Transcriptional regulator
MA06_RS03615	COG2814	Major facilitator Superfamily
MA06_RS03635	COG2249	NAD(P)H dehydrogenase (quinone) activity
MA06_RS03660	COG1122	ATPase activity
MA06_RS03690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MA06_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS03720	COG1131	(ABC) transporter
MA06_RS03735	COG1011	Hydrolase
MA06_RS03740	COG2365	Tyrosine phosphatase family
MA06_RS03765	COG0628	permease
MA06_RS03795	COG0477	Major facilitator Superfamily
MA06_RS03805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS03810	COG2318	DinB family
MA06_RS03820	COG0579	oxidoreductase
MA06_RS03840	COG1253	flavin adenine dinucleotide binding
MA06_RS03845	COG0789	Transcriptional regulator
MA06_RS03860	COG0697	spore germination
MA06_RS03865	COG1357	PFAM Pentapeptide repeats (8 copies)
MA06_RS03870	COG0583	DNA-binding transcription factor activity
MA06_RS03875	COG1335	isochorismatase
MA06_RS03880	COG3813	Protein conserved in bacteria
MA06_RS03890	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS03915	COG0384	phenazine biosynthesis protein PhzF
MA06_RS03935	COG2249	NAD(P)H dehydrogenase (quinone) activity
MA06_RS03940	COG1733	regulation of RNA biosynthetic process
MA06_RS03960	COG2271	Major facilitator Superfamily
MA06_RS03965	COG1556	Lactate utilization protein
MA06_RS03970	COG1139	Iron-sulfur cluster binding protein
MA06_RS03980	COG0583	DNA-binding transcription factor activity
MA06_RS04030	COG2072	flavoprotein involved in K transport
MA06_RS04065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MA06_RS04075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS04085	COG1923	regulation of RNA biosynthetic process
MA06_RS04090	COG2002	toxin-antitoxin pair type II binding
MA06_RS04095	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MA06_RS04135	COG0714	Associated with various cellular activities
MA06_RS04195	COG0590	tRNA wobble adenosine to inosine editing
MA06_RS04200	COG1309	transcriptional regulator
MA06_RS04205	COG2205	protein histidine kinase activity
MA06_RS04210	COG0745	RESPONSE REGULATOR receiver
MA06_RS04220	COG0577	efflux transmembrane transporter activity
MA06_RS04225	COG1136	(ABC) transporter
MA06_RS04235	COG2207	Transcriptional regulator
MA06_RS04250	COG0577	efflux transmembrane transporter activity
MA06_RS04255	COG1136	(ABC) transporter
MA06_RS04265	COG3409	Peptidoglycan-binding domain 1 protein
MA06_RS04265	COG5632	N-Acetylmuramoyl-L-alanine amidase
MA06_RS04280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MA06_RS04290	COG0494	nUDIX hydrolase
MA06_RS04310	COG0577	efflux transmembrane transporter activity
MA06_RS04315	COG1136	(ABC) transporter
MA06_RS04380	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MA06_RS04420	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MA06_RS04425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MA06_RS04440	COG3739	integral membrane protein
MA06_RS04445	COG0583	DNA-binding transcription factor activity
MA06_RS04460	COG1193	negative regulation of DNA recombination
MA06_RS04465	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MA06_RS04490	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MA06_RS04505	COG0534	Mate efflux family protein
MA06_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS04515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MA06_RS04530	COG1164	Oligoendopeptidase f
MA06_RS04535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MA06_RS04545	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MA06_RS04560	COG4851	CamS sex pheromone cAM373 precursor
MA06_RS04565	COG0577	efflux transmembrane transporter activity
MA06_RS04570	COG1136	(ABC) transporter
MA06_RS04625	COG3781	membrane
MA06_RS04635	COG0681	Belongs to the peptidase S26 family
MA06_RS04640	COG0768	penicillin binding
MA06_RS04650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MA06_RS04660	COG0277	FAD linked oxidase domain protein
MA06_RS04665	COG3196	Protein conserved in bacteria
MA06_RS04690	COG2720	vancomycin resistance protein
MA06_RS04705	COG0438	transferase activity, transferring glycosyl groups
MA06_RS04780	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS04790	COG0165	Argininosuccinate lyase
MA06_RS04810	COG4145	pantothenate transmembrane transporter activity
MA06_RS04820	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS04835	COG1657	PFAM Prenyltransferase squalene oxidase
MA06_RS04840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
MA06_RS04845	COG2962	Rard protein
MA06_RS04850	COG3326	Membrane
MA06_RS04855	COG0531	amino acid
MA06_RS04860	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS04890	COG2226	methyltransferase
MA06_RS04895	COG4166	transmembrane transport
MA06_RS04900	COG4166	transmembrane transport
MA06_RS04905	COG4166	transmembrane transport
MA06_RS04910	COG1316	TRANSCRIPTIONal
MA06_RS04920	COG1595	DNA-templated transcription, initiation
MA06_RS04930	COG1131	(ABC) transporter
MA06_RS04940	COG0673	inositol 2-dehydrogenase activity
MA06_RS04965	COG0697	spore germination
MA06_RS04980	COG1104	cysteine desulfurase activity
MA06_RS04985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MA06_RS04990	COG0187	DNA topoisomerase II activity
MA06_RS04995	COG1832	CoA-binding protein
MA06_RS05000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MA06_RS05005	COG0745	RESPONSE REGULATOR receiver
MA06_RS05015	COG1328	CTP reductase activity
MA06_RS05025	COG4841	protein insertion into membrane
MA06_RS05030	COG0824	Thioesterase
MA06_RS05055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS05070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MA06_RS05105	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MA06_RS05115	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS05135	COG3023	N-Acetylmuramoyl-L-alanine amidase
MA06_RS05145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS05155	COG5002	protein histidine kinase activity
MA06_RS05160	COG0069	glutamate synthase activity
MA06_RS05165	COG1902	pentaerythritol trinitrate reductase activity
MA06_RS05170	COG1329	Transcriptional regulator
MA06_RS05175	COG0010	Belongs to the arginase family
MA06_RS05190	COG2986	histidine ammonia-lyase
MA06_RS05225	COG4846	Membrane protein involved in cytochrome C biogenesis
MA06_RS05230	COG0785	Cytochrome C biogenesis protein
MA06_RS05240	COG1473	amidohydrolase
MA06_RS05250	COG1131	(ABC) transporter
MA06_RS05265	COG0583	DNA-binding transcription factor activity
MA06_RS05270	COG1380	Effector of murein hydrolase LrgA
MA06_RS05275	COG1346	cytolysis
MA06_RS05280	COG4187	Peptidase family M20/M25/M40
MA06_RS05285	COG1414	Transcriptional regulator
MA06_RS05300	COG3647	Membrane
MA06_RS05305	COG0730	response to heat
MA06_RS05330	COG1132	(ABC) transporter
MA06_RS05335	COG1132	(ABC) transporter
MA06_RS05365	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS05375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MA06_RS05395	COG1695	Transcriptional regulator
MA06_RS05420	COG0714	Associated with various cellular activities
MA06_RS05425	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
MA06_RS05430	COG1305	Transglutaminase-like
MA06_RS05460	COG0457	Tetratricopeptide repeat
MA06_RS05475	COG5632	N-Acetylmuramoyl-L-alanine amidase
MA06_RS05505	COG5632	N-Acetylmuramoyl-L-alanine amidase
MA06_RS05510	COG0174	glutamine synthetase
MA06_RS05515	COG0789	Transcriptional regulator
MA06_RS05520	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
MA06_RS05525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MA06_RS05530	COG2860	membrane
MA06_RS05535	COG0464	growth
MA06_RS05565	COG1388	LysM domain
MA06_RS05565	COG3584	3D domain protein
MA06_RS05570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MA06_RS05570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MA06_RS05570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MA06_RS05575	COG1105	Belongs to the carbohydrate kinase PfkB family
MA06_RS05580	COG1349	DNA-binding transcription factor activity
MA06_RS05585	COG1979	alcohol dehydrogenase
MA06_RS05590	COG2322	membrane
MA06_RS05610	COG2116	formate transmembrane transporter activity
MA06_RS05620	COG1937	Protein conserved in bacteria
MA06_RS05625	COG2819	hydrolase of the alpha beta superfamily
MA06_RS05630	COG1120	ATPase activity
MA06_RS05635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS05640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS05645	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MA06_RS05650	COG0708	Exodeoxyribonuclease III
MA06_RS05655	COG2169	Transcriptional regulator
MA06_RS05660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MA06_RS05665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MA06_RS05670	COG2195	Cleaves the N-terminal amino acid of tripeptides
MA06_RS05675	COG2364	Membrane
MA06_RS05680	COG0346	lactoylglutathione lyase activity
MA06_RS05710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS05720	COG1113	amino acid transport
MA06_RS05740	COG0577	efflux transmembrane transporter activity
MA06_RS05745	COG1136	(ABC) transporter
MA06_RS05760	COG4846	Membrane protein involved in cytochrome C biogenesis
MA06_RS05775	COG2720	vancomycin resistance protein
MA06_RS05790	COG1309	transcriptional regulator
MA06_RS05810	COG2205	protein histidine kinase activity
MA06_RS05815	COG0745	RESPONSE REGULATOR receiver
MA06_RS05830	COG1136	(ABC) transporter
MA06_RS05870	COG1819	glycosyl
MA06_RS05875	COG1819	glycosyl
MA06_RS05925	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS05940	COG0302	gtp cyclohydrolase
MA06_RS05950	COG0720	synthase
MA06_RS05970	COG4555	ABC transporter
MA06_RS05980	COG2226	methyltransferase
MA06_RS06025	COG3681	Belongs to the UPF0597 family
MA06_RS06075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS06115	COG3848	Pyruvate phosphate dikinase
MA06_RS06115	COG0574	Belongs to the PEP-utilizing enzyme family
MA06_RS06120	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MA06_RS06135	COG4550	Control of competence regulator ComK, YlbF/YmcA
MA06_RS06145	COG1013	pyruvate-flavodoxin oxidoreductase activity
MA06_RS06150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MA06_RS06150	COG0674	pyruvate-flavodoxin oxidoreductase activity
MA06_RS06160	COG2359	stage V sporulation protein S
MA06_RS06165	COG1692	metallophosphoesterase
MA06_RS06170	COG1418	mRNA catabolic process
MA06_RS06175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MA06_RS06180	COG1058	Belongs to the CinA family
MA06_RS06180	COG1546	Belongs to the CinA family
MA06_RS06185	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MA06_RS06190	COG1426	Protein conserved in bacteria
MA06_RS06205	COG0300	oxidoreductase activity
MA06_RS06210	COG0612	Peptidase, M16
MA06_RS06215	COG0612	Peptidase, M16
MA06_RS06220	COG1079	Belongs to the binding-protein-dependent transport system permease family
MA06_RS06225	COG4603	Belongs to the binding-protein-dependent transport system permease family
MA06_RS06230	COG3845	ABC transporter
MA06_RS06235	COG1744	ABC transporter substrate-binding protein PnrA-like
MA06_RS06240	COG2188	Transcriptional regulator
MA06_RS06245	COG1674	ftsk spoiiie
MA06_RS06255	COG0740	serine-type endopeptidase activity
MA06_RS06260	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MA06_RS06270	COG0527	aspartate kinase activity
MA06_RS06275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MA06_RS06280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MA06_RS06300	COG0457	Tetratricopeptide repeat
MA06_RS06345	COG1802	Transcriptional regulator
MA06_RS06345	COG4626	Terminase
MA06_RS06350	COG5484	DNA packaging
MA06_RS06385	COG0582	viral genome integration into host DNA
MA06_RS06420	COG0305	Participates in initiation and elongation during chromosome replication
MA06_RS06450	COG1396	sequence-specific DNA binding
MA06_RS06475	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MA06_RS06480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MA06_RS06485	COG1873	PFAM PRC-barrel domain
MA06_RS06490	COG0612	Peptidase, M16
MA06_RS06495	COG0726	polysaccharide deacetylase
MA06_RS06510	COG0196	riboflavin kinase activity
MA06_RS06520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MA06_RS06525	COG1550	Protein conserved in bacteria
MA06_RS06535	COG1358	cellular component organization or biogenesis
MA06_RS06540	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MA06_RS06545	COG0195	Participates in both transcription termination and antitermination
MA06_RS06550	COG0779	Required for maturation of 30S ribosomal subunits
MA06_RS06565	COG0750	zinc metalloprotease
MA06_RS06575	COG4589	Belongs to the CDS family
MA06_RS06585	COG0233	cytoplasmic translational termination
MA06_RS06590	COG0528	UMP kinase activity
MA06_RS06595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MA06_RS06600	COG0052	Belongs to the universal ribosomal protein uS2 family
MA06_RS06610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MA06_RS06615	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MA06_RS06620	COG4974	Belongs to the 'phage' integrase family
MA06_RS06625	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MA06_RS06630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MA06_RS06635	COG0758	DNA mediated transformation
MA06_RS06640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MA06_RS06670	COG0336	Belongs to the RNA methyltransferase TrmD family
MA06_RS06675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MA06_RS06680	COG1837	Belongs to the UPF0109 family
MA06_RS06690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MA06_RS06700	COG0552	protein localization to endoplasmic reticulum
MA06_RS06705	COG1196	nuclear chromosome segregation
MA06_RS06715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MA06_RS06720	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS06725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MA06_RS06740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MA06_RS06745	COG1461	Dihydroxyacetone kinase
MA06_RS06750	COG1302	Protein conserved in bacteria
MA06_RS06765	COG1564	THIamine pyrophosphokinase
MA06_RS06770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MA06_RS06780	COG0515	serine threonine protein kinase
MA06_RS06780	COG2815	serine threonine protein kinase
MA06_RS06785	COG0631	protein serine/threonine phosphatase activity
MA06_RS06790	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MA06_RS06795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MA06_RS06795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MA06_RS06805	COG0242	peptide deformylase activity
MA06_RS06810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MA06_RS06815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MA06_RS06835	COG1561	YicC-like family, N-terminal region
MA06_RS06840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MA06_RS06850	COG0006	proline dipeptidase activity
MA06_RS06880	COG0596	Alpha beta hydrolase
MA06_RS06885	COG2707	UPF0756 membrane protein
MA06_RS06895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MA06_RS06915	COG0543	2 iron, 2 sulfur cluster binding
MA06_RS06935	COG0540	Belongs to the ATCase OTCase family
MA06_RS06950	COG0564	pseudouridine synthase activity
MA06_RS06955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MA06_RS06970	COG3599	regulation of cell shape
MA06_RS06975	COG2302	S4 RNA-binding domain
MA06_RS06980	COG0762	integral membrane protein
MA06_RS06985	COG1799	cell septum assembly
MA06_RS06990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MA06_RS07000	COG1873	PFAM PRC-barrel domain
MA06_RS07005	COG1191	sigma factor activity
MA06_RS07010	COG1191	sigma factor activity
MA06_RS07020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MA06_RS07025	COG0849	cell division
MA06_RS07030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MA06_RS07040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MA06_RS07045	COG0772	Belongs to the SEDS family
MA06_RS07055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MA06_RS07060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MA06_RS07065	COG0768	penicillin binding
MA06_RS07070	COG0768	penicillin binding
MA06_RS07085	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MA06_RS07090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MA06_RS07105	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MA06_RS07110	COG1399	metal-binding, possibly nucleic acid-binding protein
MA06_RS07115	COG1323	Belongs to the UPF0348 family
MA06_RS07120	COG3480	Lon protease (S16) C-terminal proteolytic domain
MA06_RS07125	COG1752	Esterase of the alpha-beta hydrolase superfamily
MA06_RS07130	COG3314	Sporulation integral membrane protein YlbJ
MA06_RS07135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MA06_RS07140	COG0742	ribosomal rna small subunit methyltransferase
MA06_RS07160	COG4471	UPF0298 protein
MA06_RS07165	COG3679	Belongs to the UPF0342 family
MA06_RS07170	COG0406	alpha-ribazole phosphatase activity
MA06_RS07185	COG2340	Cysteine-rich secretory protein family
MA06_RS07195	COG3336	cytochrome c oxidase
MA06_RS07220	COG0109	protoheme IX farnesyltransferase activity
MA06_RS07225	COG1612	heme a metabolic process
MA06_RS07230	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MA06_RS07235	COG0772	Belongs to the SEDS family
MA06_RS07245	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MA06_RS07250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MA06_RS07260	COG4896	Protein conserved in bacteria
MA06_RS07275	COG1217	gtp-binding protein TYPA
MA06_RS07285	COG0483	inositol monophosphate 1-phosphatase activity
MA06_RS07305	COG1982	Orn Lys Arg decarboxylase major
MA06_RS07365	COG0022	dehydrogenase e1 component
MA06_RS07370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MA06_RS07385	COG0561	phosphatase activity
MA06_RS07390	COG5503	Protein of unknown function (DUF1447)
MA06_RS07395	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MA06_RS07400	COG0569	domain protein
MA06_RS07410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS07415	COG0450	alkyl hydroperoxide reductase
MA06_RS07420	COG1473	amidohydrolase
MA06_RS07430	COG0583	DNA-binding transcription factor activity
MA06_RS07435	COG0517	IMP dehydrogenase activity
MA06_RS07445	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
MA06_RS07450	COG4703	Protein of unknown function (DUF1797)
MA06_RS07465	COG2200	EAL domain
MA06_RS07470	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS07475	COG1408	metallophosphoesterase
MA06_RS07485	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MA06_RS07520	COG2814	Major facilitator Superfamily
MA06_RS07540	COG3209	COG3209 Rhs family protein
MA06_RS07550	COG2205	protein histidine kinase activity
MA06_RS07560	COG0436	Aminotransferase
MA06_RS07575	COG0366	Alpha amylase catalytic
MA06_RS07580	COG3842	ATPase activity
MA06_RS07585	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS07620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MA06_RS07625	COG0183	Belongs to the thiolase family
MA06_RS07655	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS07665	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MA06_RS07670	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MA06_RS07675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MA06_RS07680	COG0436	Aminotransferase
MA06_RS07685	COG1850	ribulose-bisphosphate carboxylase activity
MA06_RS07695	COG0235	Class ii aldolase
MA06_RS07715	COG2084	Dehydrogenase
MA06_RS07720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MA06_RS07725	COG2199	diguanylate cyclase activity
MA06_RS07730	COG0778	Nitroreductase
MA06_RS07755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MA06_RS07755	COG1263	PTS System
MA06_RS07755	COG2190	(PTS) system
MA06_RS07760	COG3711	transcriptional antiterminator
MA06_RS07765	COG0561	phosphatase activity
MA06_RS07770	COG2188	Transcriptional regulator
MA06_RS07780	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MA06_RS07790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MA06_RS07795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MA06_RS07800	COG1547	Domain of unknown function (DUF309)
MA06_RS07805	COG0456	acetyltransferase
MA06_RS07810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MA06_RS07815	COG4086	secreted protein
MA06_RS07820	COG0561	phosphatase activity
MA06_RS07825	COG0697	spore germination
MA06_RS07840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MA06_RS07875	COG1686	Belongs to the peptidase S11 family
MA06_RS07880	COG1725	Transcriptional regulator
MA06_RS07885	COG1131	(ABC) transporter
MA06_RS07905	COG1846	Transcriptional regulator
MA06_RS07920	COG0598	Magnesium transport protein CorA
MA06_RS07945	COG4974	Belongs to the 'phage' integrase family
MA06_RS07955	COG0735	belongs to the Fur family
MA06_RS07960	COG1300	Membrane
MA06_RS07980	COG0667	Aldo Keto reductase
MA06_RS07985	COG0656	L-ascorbic acid biosynthetic process
MA06_RS07995	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MA06_RS07995	COG0456	acetyltransferase
MA06_RS08005	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS08005	COG1525	nuclease
MA06_RS08005	COG4085	toxin activity
MA06_RS08010	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MA06_RS08020	COG0596	Alpha beta hydrolase
MA06_RS08025	COG2056	Na+-H+ antiporter family
MA06_RS08030	COG1609	Transcriptional regulator
MA06_RS08035	COG0456	acetyltransferase
MA06_RS08040	COG1073	alpha beta
MA06_RS08060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MA06_RS08065	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MA06_RS08065	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MA06_RS08070	COG0307	riboflavin synthase, alpha
MA06_RS08075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MA06_RS08075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MA06_RS08100	COG4106	trans-aconitate 2-methyltransferase activity
MA06_RS08105	COG1073	alpha beta
MA06_RS08105	COG2226	methyltransferase
MA06_RS08110	COG0156	8-amino-7-oxononanoate synthase activity
MA06_RS08120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MA06_RS08130	COG1757	Na H antiporter
MA06_RS08135	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS08175	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MA06_RS08185	COG0300	oxidoreductase activity
MA06_RS08190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS08195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MA06_RS08200	COG1760	l-serine dehydratase
MA06_RS08205	COG1760	l-serine dehydratase
MA06_RS08215	COG1234	tRNA 3'-trailer cleavage
MA06_RS08240	COG2195	Cleaves the N-terminal amino acid of tripeptides
MA06_RS08245	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS08255	COG1376	ErfK ybiS ycfS ynhG family protein
MA06_RS08260	COG4129	membrane
MA06_RS08265	COG1126	abc transporter atp-binding protein
MA06_RS08270	COG0765	amino acid transport
MA06_RS08275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MA06_RS08290	COG2816	NAD+ diphosphatase activity
MA06_RS08295	COG2323	membrane
MA06_RS08300	COG0772	Belongs to the SEDS family
MA06_RS08305	COG0508	dehydrogenase complex catalyzes the overall conversion of
MA06_RS08310	COG0022	dehydrogenase e1 component
MA06_RS08315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MA06_RS08320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MA06_RS08325	COG3426	butyrate kinase activity
MA06_RS08335	COG0280	phosphate acetyltransferase
MA06_RS08340	COG3290	protein histidine kinase activity
MA06_RS08340	COG3829	transcription factor binding
MA06_RS08350	COG0584	glycerophosphoryl diester phosphodiesterase
MA06_RS08355	COG0457	Tetratricopeptide repeat
MA06_RS08370	COG0745	RESPONSE REGULATOR receiver
MA06_RS08375	COG0750	zinc metalloprotease
MA06_RS08380	COG0497	DNA recombination
MA06_RS08390	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MA06_RS08410	COG1722	exodeoxyribonuclease VII activity
MA06_RS08420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MA06_RS08430	COG1302	Protein conserved in bacteria
MA06_RS08435	COG0439	Biotin carboxylase
MA06_RS08440	COG0511	ligase activity, forming carbon-carbon bonds
MA06_RS08480	COG3854	ATPases associated with a variety of cellular activities
MA06_RS08505	COG0006	proline dipeptidase activity
MA06_RS08520	COG3872	metal-dependent enzyme
MA06_RS08530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MA06_RS08570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MA06_RS08580	COG1609	Transcriptional regulator
MA06_RS08590	COG2076	Multidrug Resistance protein
MA06_RS08595	COG2076	Multidrug Resistance protein
MA06_RS08610	COG1131	(ABC) transporter
MA06_RS08630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MA06_RS08640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MA06_RS08645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MA06_RS08660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS08665	COG0450	alkyl hydroperoxide reductase
MA06_RS08680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MA06_RS08700	COG4537	Required for transformation and DNA binding
MA06_RS08705	COG1459	type II secretion system
MA06_RS08710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MA06_RS08760	COG1078	dGTPase activity
MA06_RS08780	COG0646	methionine synthase
MA06_RS08780	COG1410	methionine synthase
MA06_RS08785	COG0646	methionine synthase
MA06_RS08785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MA06_RS08790	COG0626	cystathionine gamma-synthase activity
MA06_RS08795	COG0626	cystathionine gamma-synthase activity
MA06_RS08815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS08825	COG1940	carbohydrate kinase activity
MA06_RS08830	COG4483	Protein conserved in bacteria
MA06_RS08835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MA06_RS08840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MA06_RS08845	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MA06_RS08850	COG0704	Plays a role in the regulation of phosphate uptake
MA06_RS08860	COG0581	inorganic phosphate transmembrane transporter activity
MA06_RS08865	COG0573	inorganic phosphate transmembrane transporter activity
MA06_RS08870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MA06_RS08875	COG0768	penicillin binding
MA06_RS08880	COG0477	Major facilitator Superfamily
MA06_RS08885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MA06_RS08905	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MA06_RS08910	COG0735	belongs to the Fur family
MA06_RS08915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MA06_RS08920	COG1121	(ABC) transporter
MA06_RS08925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS08950	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MA06_RS08955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MA06_RS08960	COG2384	SAM-dependent methyltransferase
MA06_RS08970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MA06_RS08975	COG0358	DNA primase activity
MA06_RS08990	COG0517	IMP dehydrogenase activity
MA06_RS09000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MA06_RS09005	COG0295	cytidine deaminase activity
MA06_RS09010	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MA06_RS09020	COG1480	7TM receptor with intracellular HD hydrolase
MA06_RS09025	COG1702	phosphate starvation-inducible protein PhoH
MA06_RS09040	COG1610	YqeY-like protein
MA06_RS09045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MA06_RS09050	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MA06_RS09055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MA06_RS09060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MA06_RS09070	COG0484	heat shock protein binding
MA06_RS09090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MA06_RS09095	COG1733	regulation of RNA biosynthetic process
MA06_RS09120	COG1466	dna polymerase III delta subunit
MA06_RS09130	COG2333	competence protein COMEC
MA06_RS09130	COG0658	competence protein
MA06_RS09135	COG2131	deaminase
MA06_RS09140	COG1555	photosystem II stabilization
MA06_RS09140	COG1596	polysaccharide export
MA06_RS09145	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MA06_RS09150	COG2226	methyltransferase
MA06_RS09155	COG0799	negative regulation of ribosome biogenesis
MA06_RS09160	COG1713	HD superfamily hydrolase involved in NAD metabolism
MA06_RS09170	COG1534	Rna-binding protein
MA06_RS09180	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MA06_RS09185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MA06_RS09205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MA06_RS09210	COG2357	RelA SpoT domain protein
MA06_RS09220	COG1785	Belongs to the alkaline phosphatase family
MA06_RS09230	COG2267	carboxylic ester hydrolase activity
MA06_RS09260	COG3186	Phenylalanine-4-hydroxylase
MA06_RS09265	COG2154	pterin-4-alpha-carbinolamine dehydratase
MA06_RS09270	COG2514	catechol 2,3-dioxygenase activity
MA06_RS09275	COG2259	Doxx family
MA06_RS09310	COG1609	Transcriptional regulator
MA06_RS09325	COG1454	alcohol dehydrogenase
MA06_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS09335	COG2801	Transposase and inactivated derivatives
MA06_RS09340	COG0626	cystathionine gamma-synthase activity
MA06_RS09345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MA06_RS09355	COG2226	methyltransferase
MA06_RS09370	COG0768	penicillin binding
MA06_RS09380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MA06_RS09385	COG0572	uridine kinase
MA06_RS09390	COG0826	peptidase U32
MA06_RS09395	COG0826	peptidase U32
MA06_RS09400	COG4122	O-methyltransferase activity
MA06_RS09405	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MA06_RS09420	COG4472	Bacterial protein of unknown function (DUF965)
MA06_RS09430	COG0628	permease
MA06_RS09450	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MA06_RS09465	COG1104	cysteine desulfurase activity
MA06_RS09470	COG1959	2 iron, 2 sulfur cluster binding
MA06_RS09475	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MA06_RS09485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MA06_RS09520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MA06_RS09530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MA06_RS09530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MA06_RS09535	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MA06_RS09540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MA06_RS09540	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MA06_RS09550	COG2244	polysaccharide biosynthetic process
MA06_RS09555	COG2323	membrane
MA06_RS09565	COG1862	Preprotein translocase
MA06_RS09585	COG2255	four-way junction helicase activity
MA06_RS09595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MA06_RS09625	COG0157	Belongs to the NadC ModD family
MA06_RS09630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MA06_RS09635	COG1104	cysteine desulfurase activity
MA06_RS09640	COG1827	regulation of RNA biosynthetic process
MA06_RS09645	COG2258	MOSC domain
MA06_RS09650	COG0077	Prephenate dehydratase
MA06_RS09655	COG0577	efflux transmembrane transporter activity
MA06_RS09660	COG0577	efflux transmembrane transporter activity
MA06_RS09665	COG1136	(ABC) transporter
MA06_RS09670	COG5002	protein histidine kinase activity
MA06_RS09675	COG0745	RESPONSE REGULATOR receiver
MA06_RS09685	COG3290	protein histidine kinase activity
MA06_RS09695	COG2868	ribosomal protein
MA06_RS09705	COG1530	ribonuclease E activity
MA06_RS09710	COG1994	Peptidase M50
MA06_RS09715	COG0739	heme binding
MA06_RS09720	COG2894	cell division
MA06_RS09735	COG1792	Involved in formation and maintenance of cell shape
MA06_RS09740	COG1077	Cell shape determining protein MreB Mrl
MA06_RS09745	COG2003	Belongs to the UPF0758 family
MA06_RS09750	COG0424	maF-like protein
MA06_RS09760	COG0285	dihydrofolate synthase activity
MA06_RS09780	COG1388	LysM domain
MA06_RS09790	COG0113	porphobilinogen synthase activity
MA06_RS09795	COG1587	Uroporphyrinogen-III synthase
MA06_RS09800	COG0181	hydroxymethylbilane synthase activity
MA06_RS09805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MA06_RS09810	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MA06_RS09815	COG1846	Transcriptional regulator
MA06_RS09820	COG1764	response to oxidative stress
MA06_RS09835	COG1067	ATP-dependent peptidase activity
MA06_RS09835	COG0470	DNA polymerase III
MA06_RS09845	COG0544	peptidyl-prolyl cis-trans isomerase activity
MA06_RS09875	COG0622	Phosphoesterase
MA06_RS09885	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MA06_RS09890	COG5401	PFAM Sporulation and spore germination
MA06_RS09900	COG2197	response regulator
MA06_RS09905	COG0531	amino acid
MA06_RS09910	COG1983	PspC domain protein
MA06_RS09920	COG3250	beta-galactosidase activity
MA06_RS09925	COG0395	ABC-type sugar transport system, permease component
MA06_RS09930	COG1175	transmembrane transport
MA06_RS09940	COG2207	Transcriptional regulator
MA06_RS09940	COG4753	response regulator
MA06_RS09945	COG2972	Histidine kinase
MA06_RS09950	COG1396	sequence-specific DNA binding
MA06_RS09955	COG0697	spore germination
MA06_RS09965	COG1959	2 iron, 2 sulfur cluster binding
MA06_RS09970	COG1668	transmembrane transport
MA06_RS09975	COG4152	abc transporter atp-binding protein
MA06_RS09980	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MA06_RS09985	COG1876	peptidase activity
MA06_RS09995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MA06_RS10000	COG1053	succinate dehydrogenase
MA06_RS10005	COG2009	succinate dehydrogenase
MA06_RS10010	COG1719	4-vinyl reductase, 4VR
MA06_RS10035	COG0463	Glycosyl transferase, family 2
MA06_RS10050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MA06_RS10060	COG3118	belongs to the thioredoxin family
MA06_RS10065	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MA06_RS10070	COG2086	electron transfer activity
MA06_RS10075	COG1024	Enoyl-CoA hydratase
MA06_RS10080	COG1309	transcriptional regulator
MA06_RS10085	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS10095	COG2318	DinB family
MA06_RS10125	COG1131	(ABC) transporter
MA06_RS10130	COG2205	protein histidine kinase activity
MA06_RS10135	COG0745	RESPONSE REGULATOR receiver
MA06_RS10140	COG4895	conserved protein (DUF2196)
MA06_RS10145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MA06_RS10155	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS10170	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MA06_RS10170	COG1796	DNA polymerase
MA06_RS10175	COG1286	toxin biosynthetic process
MA06_RS10180	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MA06_RS10185	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MA06_RS10215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MA06_RS10225	COG1418	mRNA catabolic process
MA06_RS10240	COG2814	Major facilitator Superfamily
MA06_RS10245	COG1566	PFAM secretion protein HlyD family protein
MA06_RS10250	COG1309	transcriptional regulator
MA06_RS10260	COG1363	Peptidase, m42
MA06_RS10290	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MA06_RS10300	COG1484	DNA-dependent DNA replication
MA06_RS10305	COG3611	Membrane attachment protein
MA06_RS10310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MA06_RS10315	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MA06_RS10320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MA06_RS10330	COG1971	Probably functions as a manganese efflux pump
MA06_RS10340	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MA06_RS10340	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MA06_RS10350	COG5002	protein histidine kinase activity
MA06_RS10355	COG0745	RESPONSE REGULATOR receiver
MA06_RS10360	COG1742	UPF0060 membrane protein
MA06_RS10375	COG0538	isocitrate dehydrogenase activity
MA06_RS10380	COG0372	Belongs to the citrate synthase family
MA06_RS10385	COG2707	UPF0756 membrane protein
MA06_RS10390	COG0628	permease
MA06_RS10395	COG3030	protein affecting phage T7 exclusion by the F plasmid
MA06_RS10420	COG1725	Transcriptional regulator
MA06_RS10425	COG0281	malic enzyme
MA06_RS10430	COG0587	DNA-directed DNA polymerase activity
MA06_RS10445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MA06_RS10460	COG4109	DRTGG domain
MA06_RS10465	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MA06_RS10470	COG0006	proline dipeptidase activity
MA06_RS10510	COG0662	Cupin 2, conserved barrel domain protein
MA06_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS10535	COG0589	response to stress
MA06_RS10550	COG2824	Alkylphosphonate utilization operon protein PhnA
MA06_RS10570	COG0137	argininosuccinate synthase activity
MA06_RS10580	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MA06_RS10585	COG3766	membrane
MA06_RS10600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS10615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MA06_RS10620	COG0827	DNA restriction-modification system
MA06_RS10625	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MA06_RS10630	COG3874	Sporulation protein YtfJ
MA06_RS10645	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MA06_RS10655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MA06_RS10670	COG1104	cysteine desulfurase activity
MA06_RS10675	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MA06_RS10685	COG0697	spore germination
MA06_RS10690	COG1309	transcriptional regulator
MA06_RS10695	COG1956	GAF domain-containing protein
MA06_RS10700	COG0626	cystathionine gamma-synthase activity
MA06_RS10735	COG1595	DNA-templated transcription, initiation
MA06_RS10745	COG0110	maltose O-acetyltransferase activity
MA06_RS10750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MA06_RS10755	COG0454	-acetyltransferase
MA06_RS10760	COG0517	IMP dehydrogenase activity
MA06_RS10765	COG0123	including yeast histone deacetylase and acetoin utilization protein
MA06_RS10790	COG1609	Transcriptional regulator
MA06_RS10795	COG1605	Chorismate mutase
MA06_RS10795	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MA06_RS10800	COG3118	belongs to the thioredoxin family
MA06_RS10810	COG2309	aminopeptidase activity
MA06_RS10830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS10835	COG0697	spore germination
MA06_RS10840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MA06_RS10850	COG1674	ftsk spoiiie
MA06_RS10855	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS10865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MA06_RS10870	COG4848	Belongs to the UPF0354 family
MA06_RS10875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS10880	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MA06_RS10885	COG1363	Peptidase, m42
MA06_RS10895	COG0183	Belongs to the thiolase family
MA06_RS10900	COG1250	3-hydroxyacyl-CoA dehydrogenase
MA06_RS10905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MA06_RS10915	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS10920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS10935	COG0510	thiamine kinase activity
MA06_RS10940	COG1523	belongs to the glycosyl hydrolase 13 family
MA06_RS10950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MA06_RS10955	COG1349	DNA-binding transcription factor activity
MA06_RS10960	COG1187	pseudouridine synthase activity
MA06_RS10965	COG2244	polysaccharide biosynthetic process
MA06_RS10970	COG2081	HI0933 family
MA06_RS10975	COG2814	Major facilitator Superfamily
MA06_RS10985	COG3832	glyoxalase III activity
MA06_RS11005	COG1329	Transcriptional regulator
MA06_RS11015	COG2223	nitrite transmembrane transporter activity
MA06_RS11020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MA06_RS11025	COG0314	molybdopterin synthase activity
MA06_RS11030	COG1763	Mo-molybdopterin cofactor biosynthetic process
MA06_RS11035	COG0303	'Molybdopterin
MA06_RS11040	COG0315	cyclic pyranopterin monophosphate synthase activity
MA06_RS11045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MA06_RS11050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MA06_RS11055	COG1733	regulation of RNA biosynthetic process
MA06_RS11060	COG0778	Nitroreductase
MA06_RS11065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MA06_RS11070	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MA06_RS11075	COG1140	nitrate reductase beta subunit
MA06_RS11080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
MA06_RS11085	COG2181	nitrate reductase activity
MA06_RS11105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MA06_RS11110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MA06_RS11150	COG2814	Major facilitator Superfamily
MA06_RS11160	COG1136	(ABC) transporter
MA06_RS11165	COG0346	lactoylglutathione lyase activity
MA06_RS11180	COG1242	4 iron, 4 sulfur cluster binding
MA06_RS11185	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MA06_RS11190	COG1116	anion transmembrane transporter activity
MA06_RS11195	COG1794	racemase activity, acting on amino acids and derivatives
MA06_RS11215	COG2267	carboxylic ester hydrolase activity
MA06_RS11220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MA06_RS11225	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS11230	COG0438	transferase activity, transferring glycosyl groups
MA06_RS11230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MA06_RS11235	COG0746	molybdenum cofactor guanylyltransferase activity
MA06_RS11255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS11260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MA06_RS11300	COG5002	protein histidine kinase activity
MA06_RS11305	COG4191	Histidine kinase
MA06_RS11310	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MA06_RS11310	COG2755	lipolytic protein G-D-S-L family
MA06_RS11315	COG4895	conserved protein (DUF2196)
MA06_RS11320	COG1408	metallophosphoesterase
MA06_RS11335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MA06_RS11340	COG1116	anion transmembrane transporter activity
MA06_RS11345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MA06_RS11355	COG0546	phosphoglycolate phosphatase activity
MA06_RS11360	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS11365	COG0494	nUDIX hydrolase
MA06_RS11400	COG1609	Transcriptional regulator
MA06_RS11410	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MA06_RS11415	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MA06_RS11420	COG1854	S-ribosylhomocysteine lyase activity
MA06_RS11430	COG0288	reversible hydration of carbon dioxide
MA06_RS11435	COG1271	oxidase subunit
MA06_RS11440	COG1294	oxidase, subunit
MA06_RS11455	COG0583	DNA-binding transcription factor activity
MA06_RS11480	COG1842	Phage shock protein A
MA06_RS11505	COG5002	protein histidine kinase activity
MA06_RS11510	COG0745	RESPONSE REGULATOR receiver
MA06_RS11550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MA06_RS11560	COG0586	Pfam SNARE associated Golgi protein
MA06_RS11570	COG0577	efflux transmembrane transporter activity
MA06_RS11575	COG1136	(ABC) transporter
MA06_RS11580	COG2207	Transcriptional regulator
MA06_RS11580	COG3708	Transcriptional regulator
MA06_RS11590	COG1131	(ABC) transporter
MA06_RS11595	COG5658	integral membrane protein
MA06_RS11600	COG0640	Transcriptional regulator
MA06_RS11605	COG0745	RESPONSE REGULATOR receiver
MA06_RS11610	COG2205	protein histidine kinase activity
MA06_RS11615	COG0577	efflux transmembrane transporter activity
MA06_RS11620	COG1136	(ABC) transporter
MA06_RS11625	COG0577	efflux transmembrane transporter activity
MA06_RS11640	COG4948	Mandelate Racemase Muconate Lactonizing
MA06_RS11645	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS11650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MA06_RS11655	COG0596	Alpha beta hydrolase
MA06_RS11660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MA06_RS11665	COG1169	isochorismate synthase
MA06_RS11670	COG1575	Belongs to the MenA family. Type 1 subfamily
MA06_RS11675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MA06_RS11690	COG0789	Transcriptional regulator
MA06_RS11700	COG0058	SHG alpha-glucan phosphorylase activity
MA06_RS11710	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MA06_RS11715	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MA06_RS11735	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MA06_RS11840	COG0544	peptidyl-prolyl cis-trans isomerase activity
MA06_RS11875	COG1285	pathogenesis
MA06_RS11880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MA06_RS11890	COG0166	Belongs to the GPI family
MA06_RS11895	COG2155	Conserved Protein
MA06_RS11900	COG1098	S1 RNA binding domain
MA06_RS11905	COG0436	Aminotransferase
MA06_RS11910	COG1522	sequence-specific DNA binding
MA06_RS11915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MA06_RS11920	COG2267	carboxylic ester hydrolase activity
MA06_RS11930	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MA06_RS11935	COG2032	superoxide dismutase activity
MA06_RS11945	COG5018	Exonuclease
MA06_RS11950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MA06_RS11970	COG2050	protein possibly involved in aromatic compounds catabolism
MA06_RS11980	COG1268	BioY protein
MA06_RS11985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MA06_RS11990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MA06_RS12000	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MA06_RS12010	COG3584	3D domain protein
MA06_RS12030	COG1252	NADH dehydrogenase
MA06_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS12045	COG3708	Transcriptional regulator
MA06_RS12075	COG1683	Conserved Protein
MA06_RS12085	COG0316	Belongs to the HesB IscA family
MA06_RS12095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS12105	COG1252	NADH dehydrogenase
MA06_RS12115	COG0390	transport system, permease component
MA06_RS12125	COG4837	Protein of unknown function (DUF1462)
MA06_RS12130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MA06_RS12135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MA06_RS12140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MA06_RS12145	COG2359	stage V sporulation protein S
MA06_RS12155	COG2310	stress, protein
MA06_RS12170	COG1358	cellular component organization or biogenesis
MA06_RS12180	COG2304	oxidoreductase activity
MA06_RS12205	COG0577	efflux transmembrane transporter activity
MA06_RS12205	COG1136	(ABC) transporter
MA06_RS12210	COG2249	NAD(P)H dehydrogenase (quinone) activity
MA06_RS12215	COG0647	UMP catabolic process
MA06_RS12225	COG2445	Protein of unknown function DUF86
MA06_RS12230	COG1494	fructose-1,6-bisphosphatase
MA06_RS12250	COG4470	Protein conserved in bacteria
MA06_RS12260	COG0789	Transcriptional regulator
MA06_RS12265	COG4377	Putative membrane peptidase family (DUF2324)
MA06_RS12275	COG0456	acetyltransferase
MA06_RS12290	COG0739	heme binding
MA06_RS12300	COG3377	Domain of unknown function (DUF1805)
MA06_RS12305	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS12315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS12335	COG0719	Fe-S assembly protein
MA06_RS12340	COG0822	iron-sulfur transferase activity
MA06_RS12345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MA06_RS12350	COG0719	Fe-S assembly protein
MA06_RS12355	COG0396	ATPase activity
MA06_RS12360	COG1464	Belongs to the NlpA lipoprotein family
MA06_RS12365	COG2011	ABC-type metal ion transport system permease component
MA06_RS12380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS12385	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MA06_RS12395	COG0509	glycine decarboxylation via glycine cleavage system
MA06_RS12400	COG1393	Belongs to the ArsC family
MA06_RS12420	COG0039	L-malate dehydrogenase activity
MA06_RS12435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS12455	COG1960	acyl-CoA dehydrogenase activity
MA06_RS12460	COG0183	Belongs to the thiolase family
MA06_RS12465	COG1250	3-hydroxyacyl-CoA dehydrogenase
MA06_RS12465	COG1024	Enoyl-CoA hydratase
MA06_RS12470	COG1686	Belongs to the peptidase S11 family
MA06_RS12490	COG0011	TIGRFAM Protein of
MA06_RS12505	COG2814	Major facilitator Superfamily
MA06_RS12510	COG0531	amino acid
MA06_RS12530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS12555	COG0586	Pfam SNARE associated Golgi protein
MA06_RS12565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MA06_RS12575	COG0535	radical SAM domain protein
MA06_RS12580	COG2151	metal-sulfur cluster biosynthetic enzyme
MA06_RS12585	COG3227	Zinc metalloprotease (Elastase)
MA06_RS12610	COG0783	Belongs to the Dps family
MA06_RS12620	COG1611	Belongs to the LOG family
MA06_RS12625	COG1694	Mazg nucleotide pyrophosphohydrolase
MA06_RS12635	COG2311	Membrane
MA06_RS12640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS12645	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS12650	COG1115	amino acid carrier protein
MA06_RS12655	COG2910	NAD(P)H-binding
MA06_RS12665	COG1268	BioY protein
MA06_RS12670	COG0656	L-ascorbic acid biosynthetic process
MA06_RS12675	COG2814	Major facilitator Superfamily
MA06_RS12680	COG1733	regulation of RNA biosynthetic process
MA06_RS12690	COG1252	NADH dehydrogenase
MA06_RS12730	COG0531	amino acid
MA06_RS12735	COG0697	spore germination
MA06_RS12740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS12750	COG1695	Transcriptional regulator
MA06_RS12760	COG3104	oligopeptide transport
MA06_RS12805	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MA06_RS12810	COG0557	exoribonuclease II activity
MA06_RS12815	COG1647	Serine aminopeptidase, S33
MA06_RS12820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MA06_RS12825	COG1346	cytolysis
MA06_RS12840	COG0148	phosphopyruvate hydratase activity
MA06_RS12860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MA06_RS12875	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MA06_RS12900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MA06_RS12915	COG2323	membrane
MA06_RS12925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MA06_RS12930	COG1773	rubredoxin
MA06_RS12935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MA06_RS12940	COG0426	domain, Protein
MA06_RS12955	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MA06_RS12960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MA06_RS12975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MA06_RS12980	COG1481	regulation of sporulation
MA06_RS12985	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MA06_RS12995	COG1051	belongs to the nudix hydrolase family
MA06_RS13000	COG1556	Lactate utilization protein
MA06_RS13005	COG1139	Iron-sulfur cluster binding protein
MA06_RS13010	COG0247	lactate metabolic process
MA06_RS13020	COG0492	ferredoxin-NADP+ reductase activity
MA06_RS13025	COG0457	Tetratricopeptide repeat
MA06_RS13030	COG0110	maltose O-acetyltransferase activity
MA06_RS13050	COG1950	PFAM Membrane protein of
MA06_RS13055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MA06_RS13060	COG0556	nucleotide-excision repair
MA06_RS13070	COG0531	amino acid
MA06_RS13090	COG0583	DNA-binding transcription factor activity
MA06_RS13100	COG0655	NAD(P)H dehydrogenase (quinone) activity
MA06_RS13105	COG0488	(ABC) transporter
MA06_RS13115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MA06_RS13120	COG0793	Belongs to the peptidase S41A family
MA06_RS13120	COG3409	Peptidoglycan-binding domain 1 protein
MA06_RS13125	COG2177	Part of the ABC transporter FtsEX involved in
MA06_RS13130	COG2884	Cell division ATP-binding protein ftsE
MA06_RS13140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MA06_RS13160	COG1278	Cold shock
MA06_RS13165	COG1040	competence protein
MA06_RS13170	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MA06_RS13175	COG0791	NLP P60 protein
MA06_RS13175	COG1388	LysM domain
MA06_RS13175	COG3103	Sh3 type 3 domain protein
MA06_RS13180	COG1733	regulation of RNA biosynthetic process
MA06_RS13185	COG1307	EDD domain protein, DegV family
MA06_RS13190	COG1739	Uncharacterized protein family UPF0029
MA06_RS13195	COG1316	TRANSCRIPTIONal
MA06_RS13200	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MA06_RS13205	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MA06_RS13210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MA06_RS13220	COG3933	PFAM sigma-54 factor interaction domain-containing protein
MA06_RS13220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MA06_RS13240	COG1486	melibiose metabolic process
MA06_RS13245	COG1447	Phosphotransferase system cellobiose-specific component IIA
MA06_RS13250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MA06_RS13270	COG1447	Phosphotransferase system cellobiose-specific component IIA
MA06_RS13280	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MA06_RS13285	COG1301	dicarboxylic acid transport
MA06_RS13305	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MA06_RS13310	COG1271	oxidase subunit
MA06_RS13315	COG1294	oxidase, subunit
MA06_RS13325	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MA06_RS13340	COG1620	l-lactate permease
MA06_RS13345	COG2389	metal-binding protein
MA06_RS13360	COG1368	sulfuric ester hydrolase activity
MA06_RS13370	COG0791	NLP P60 protein
MA06_RS13370	COG1388	LysM domain
MA06_RS13380	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS13385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MA06_RS13390	COG1388	LysM domain
MA06_RS13390	COG3584	3D domain protein
MA06_RS13415	COG4715	Zinc finger, swim domain protein
MA06_RS13420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MA06_RS13460	COG0577	efflux transmembrane transporter activity
MA06_RS13465	COG1136	(ABC) transporter
MA06_RS13485	COG2271	Major facilitator Superfamily
MA06_RS13500	COG3850	Histidine kinase
MA06_RS13500	COG5002	protein histidine kinase activity
MA06_RS13505	COG0745	RESPONSE REGULATOR receiver
MA06_RS13510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MA06_RS13515	COG4750	Nucleotidyl transferase
MA06_RS13520	COG0697	spore germination
MA06_RS13530	COG3475	LICD family
MA06_RS13535	COG1316	TRANSCRIPTIONal
MA06_RS13540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MA06_RS13545	COG3764	Sortase (surface protein transpeptidase)
MA06_RS13555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MA06_RS13560	COG0110	maltose O-acetyltransferase activity
MA06_RS13565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MA06_RS13605	COG4464	protein tyrosine phosphatase activity
MA06_RS13610	COG0489	protein tyrosine kinase activity
MA06_RS13615	COG3944	biosynthesis protein
MA06_RS13625	COG1132	(ABC) transporter
MA06_RS13655	COG0367	asparagine synthase
MA06_RS13660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MA06_RS13670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MA06_RS13680	COG1215	transferase activity, transferring glycosyl groups
MA06_RS13695	COG0110	maltose O-acetyltransferase activity
MA06_RS13715	COG1215	transferase activity, transferring glycosyl groups
MA06_RS13740	COG0463	Glycosyl transferase, family 2
MA06_RS13740	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MA06_RS13745	COG0438	transferase activity, transferring glycosyl groups
MA06_RS13750	COG1216	Glycosyl transferase, family 2
MA06_RS13755	COG0438	transferase activity, transferring glycosyl groups
MA06_RS13760	COG1086	Polysaccharide biosynthesis protein
MA06_RS13765	COG0489	protein tyrosine kinase activity
MA06_RS13770	COG3944	biosynthesis protein
MA06_RS13780	COG1134	teichoic acid transport
MA06_RS13785	COG1682	transport, permease protein
MA06_RS13790	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MA06_RS13795	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MA06_RS13805	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MA06_RS13810	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MA06_RS13820	COG1609	Transcriptional regulator
MA06_RS13825	COG0739	heme binding
MA06_RS13840	COG4555	ABC transporter
MA06_RS13845	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS13850	COG2385	sporulation resulting in formation of a cellular spore
MA06_RS13865	COG4836	Membrane
MA06_RS13870	COG1007	ATP synthesis coupled electron transport
MA06_RS13875	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MA06_RS13880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MA06_RS13885	COG0713	ATP synthesis coupled electron transport
MA06_RS13890	COG0839	Belongs to the complex I subunit 6 family
MA06_RS13900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MA06_RS13905	COG0649	NAD binding
MA06_RS13910	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MA06_RS13920	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MA06_RS13935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MA06_RS13940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MA06_RS13950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MA06_RS13955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MA06_RS13960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MA06_RS13970	COG0356	it plays a direct role in the translocation of protons across the membrane
MA06_RS13990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MA06_RS14005	COG0698	ribose 5-phosphate isomerase
MA06_RS14020	COG2259	Doxx family
MA06_RS14025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MA06_RS14035	COG1971	Probably functions as a manganese efflux pump
MA06_RS14040	COG0009	L-threonylcarbamoyladenylate synthase
MA06_RS14060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MA06_RS14075	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MA06_RS14080	COG1494	fructose-1,6-bisphosphatase
MA06_RS14100	COG4821	SIS domain
MA06_RS14120	COG1960	acyl-CoA dehydrogenase activity
MA06_RS14125	COG1960	acyl-CoA dehydrogenase activity
MA06_RS14140	COG2181	nitrate reductase activity
MA06_RS14140	COG0247	lactate metabolic process
MA06_RS14145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MA06_RS14150	COG4294	response to UV
MA06_RS14170	COG2197	response regulator
MA06_RS14175	COG4585	Histidine kinase
MA06_RS14180	COG0842	Transport permease protein
MA06_RS14185	COG1131	(ABC) transporter
MA06_RS14190	COG0024	Methionine aminopeptidase
MA06_RS14195	COG2234	aminopeptidase activity
MA06_RS14215	COG1619	proteins homologs of microcin C7 resistance protein MccF
MA06_RS14235	COG0010	Belongs to the arginase family
MA06_RS14245	COG2814	Major facilitator Superfamily
MA06_RS14250	COG0789	Transcriptional regulator
MA06_RS14255	COG0584	glycerophosphoryl diester phosphodiesterase
MA06_RS14260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MA06_RS14270	COG1994	Peptidase M50
MA06_RS14280	COG1078	dGTPase activity
MA06_RS14285	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MA06_RS14290	COG1120	ATPase activity
MA06_RS14295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS14300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS14305	COG4844	belongs to the
MA06_RS14325	COG0280	phosphate acetyltransferase
MA06_RS14330	COG3253	May function as heme-dependent peroxidase
MA06_RS14340	COG3773	Cell wall hydrolase
MA06_RS14350	COG2363	Small membrane protein
MA06_RS14360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MA06_RS14365	COG2233	PERMEase
MA06_RS14370	COG0561	phosphatase activity
MA06_RS14375	COG2814	Major facilitator Superfamily
MA06_RS14380	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MA06_RS14385	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MA06_RS14390	COG1131	(ABC) transporter
MA06_RS14395	COG2755	lipolytic protein G-D-S-L family
MA06_RS14400	COG1609	Transcriptional regulator
MA06_RS14410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MA06_RS14415	COG0460	homoserine dehydrogenase
MA06_RS14420	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MA06_RS14425	COG2873	o-acetylhomoserine
MA06_RS14445	COG1011	Hydrolase
MA06_RS14450	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MA06_RS14460	COG2197	response regulator
MA06_RS14465	COG2203	Gaf domain
MA06_RS14465	COG4585	Histidine kinase
MA06_RS14470	COG0351	phosphomethylpyrimidine kinase
MA06_RS14480	COG1966	Carbon starvation protein
MA06_RS14485	COG3279	Response regulator of the LytR AlgR family
MA06_RS14490	COG0477	Major facilitator Superfamily
MA06_RS14495	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MA06_RS14500	COG0438	transferase activity, transferring glycosyl groups
MA06_RS14520	COG1607	acyl-coa hydrolase
MA06_RS14545	COG0488	(ABC) transporter
MA06_RS14565	COG0463	Glycosyl transferase, family 2
MA06_RS14570	COG1309	transcriptional regulator
MA06_RS14575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MA06_RS14580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MA06_RS14580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MA06_RS14585	COG0628	permease
MA06_RS14600	COG3279	Response regulator of the LytR AlgR family
MA06_RS14605	COG3275	phosphorelay sensor kinase activity
MA06_RS14615	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MA06_RS14635	COG1272	protein, Hemolysin III
MA06_RS14670	COG1301	dicarboxylic acid transport
MA06_RS14675	COG4565	transcriptional regulatory protein
MA06_RS14680	COG3290	protein histidine kinase activity
MA06_RS14685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MA06_RS14710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MA06_RS14715	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MA06_RS14730	COG5002	protein histidine kinase activity
MA06_RS14735	COG0745	RESPONSE REGULATOR receiver
MA06_RS14760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MA06_RS14765	COG0305	Participates in initiation and elongation during chromosome replication
MA06_RS14775	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
MA06_RS14780	COG4241	membrane
MA06_RS14795	COG0360	Binds together with S18 to 16S ribosomal RNA
MA06_RS14800	COG0012	GTP binding
MA06_RS14805	COG4481	Protein conserved in bacteria
MA06_RS14810	COG0668	transmembrane transport
MA06_RS14820	COG1475	DNA binding
MA06_RS14825	COG1192	Involved in chromosome partitioning
MA06_RS14840	COG0445	tRNA wobble uridine modification
MA06_RS14850	COG1847	R3H domain protein
MA06_RS14855	COG0706	membrane insertase activity
MA06_RS14860	COG0594	ribonuclease P activity
MA06_RS14865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MA06_RS14870	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MA06_RS14875	COG0592	DNA-directed DNA polymerase activity
MA06_RS14880	COG2501	S4 domain
MA06_RS14890	COG0187	DNA topoisomerase II activity
MA06_RS14895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MA06_RS14930	COG0517	IMP dehydrogenase activity
MA06_RS14930	COG0516	GMP reductase activity
MA06_RS14935	COG1686	Belongs to the peptidase S11 family
MA06_RS14965	COG1428	Deoxynucleoside kinase
MA06_RS14970	COG1428	Deoxynucleoside kinase
MA06_RS14975	COG1335	isochorismatase
MA06_RS14980	COG0590	tRNA wobble adenosine to inosine editing
MA06_RS14985	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MA06_RS14995	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MA06_RS15035	COG1982	Orn Lys Arg decarboxylase major
MA06_RS15045	COG0470	DNA polymerase III
MA06_RS15050	COG1774	PSP1 C-terminal conserved region
MA06_RS15055	COG4467	Involved in initiation control of chromosome replication
MA06_RS15060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MA06_RS15070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MA06_RS15075	COG2002	toxin-antitoxin pair type II binding
MA06_RS15085	COG0084	hydrolase, TatD family'
MA06_RS15095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MA06_RS15105	COG4466	Protein conserved in bacteria
MA06_RS15120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MA06_RS15125	COG0251	oxidation-reduction process
MA06_RS15130	COG2088	sporulation resulting in formation of a cellular spore
MA06_RS15135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MA06_RS15155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MA06_RS15160	COG2002	toxin-antitoxin pair type II binding
MA06_RS15165	COG2244	polysaccharide biosynthetic process
MA06_RS15170	COG3956	TIGRFAM MazG family protein
MA06_RS15175	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MA06_RS15195	COG1098	S1 RNA binding domain
MA06_RS15210	COG2208	phosphoserine phosphatase activity
MA06_RS15220	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
MA06_RS15225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MA06_RS15240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MA06_RS15245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MA06_RS15250	COG0512	Glutamine amidotransferase of anthranilate synthase
MA06_RS15255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MA06_RS15260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MA06_RS15265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MA06_RS15270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MA06_RS15275	COG1396	sequence-specific DNA binding
MA06_RS15280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MA06_RS15320	COG0544	peptidyl-prolyl cis-trans isomerase activity
MA06_RS15370	COG3880	PFAM UvrB UvrC protein
MA06_RS15380	COG0542	response to heat
MA06_RS15385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MA06_RS15395	COG4956	integral membrane protein (PIN domain superfamily)
MA06_RS15400	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MA06_RS15415	COG1045	serine acetyltransferase
MA06_RS15430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MA06_RS15435	COG3688	RNA-binding protein containing a PIN domain
MA06_RS15445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MA06_RS15450	COG0250	Participates in transcription elongation, termination and antitermination
MA06_RS15455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MA06_RS15465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MA06_RS15470	COG0222	ribosome binding
MA06_RS15475	COG2813	Specifically methylates the guanine in position
MA06_RS15490	COG1358	cellular component organization or biogenesis
MA06_RS15495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MA06_RS15505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MA06_RS15510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MA06_RS15520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MA06_RS15525	COG0088	Forms part of the polypeptide exit tunnel
MA06_RS15530	COG0089	rRNA binding
MA06_RS15560	COG0255	Belongs to the universal ribosomal protein uL29 family
MA06_RS15565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MA06_RS15575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MA06_RS15620	COG0201	protein transport
MA06_RS15625	COG0563	adenylate kinase activity
MA06_RS15630	COG0024	Methionine aminopeptidase
MA06_RS15640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MA06_RS15645	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MA06_RS15655	COG0202	RNA polymerase activity
MA06_RS15675	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MA06_RS15705	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS15710	COG0489	protein tyrosine kinase activity
MA06_RS15720	COG2194	sulfuric ester hydrolase activity
MA06_RS15725	COG0726	polysaccharide deacetylase
MA06_RS15815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MA06_RS15820	COG4856	YbbR-like protein
MA06_RS15860	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MA06_RS15870	COG2814	Major facilitator Superfamily
MA06_RS15900	COG4166	transmembrane transport
MA06_RS15920	COG4149	molybdate abc transporter
MA06_RS15930	COG1910	domain protein
MA06_RS15935	COG0204	Acyl-transferase
MA06_RS15940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS15945	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MA06_RS15945	COG1648	precorrin-2 dehydrogenase activity
MA06_RS15955	COG1587	Uroporphyrinogen-III synthase
MA06_RS15955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MA06_RS15960	COG2146	nitrite reductase [NAD(P)H] activity
MA06_RS15965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MA06_RS15980	COG0084	hydrolase, TatD family'
MA06_RS16005	COG0488	(ABC) transporter
MA06_RS16010	COG4585	Histidine kinase
MA06_RS16015	COG2197	response regulator
MA06_RS16020	COG1131	(ABC) transporter
MA06_RS16025	COG0842	Transport permease protein
MA06_RS16025	COG1511	domain protein
MA06_RS16030	COG0842	Transport permease protein
MA06_RS16040	COG0747	negative chemotaxis
MA06_RS16045	COG0601	transmembrane transport
MA06_RS16055	COG0444	Belongs to the ABC transporter superfamily
MA06_RS16060	COG4608	Belongs to the ABC transporter superfamily
MA06_RS16065	COG0561	phosphatase activity
MA06_RS16095	COG3185	4-Hydroxyphenylpyruvate dioxygenase
MA06_RS16100	COG0179	Fumarylacetoacetate (FAA) hydrolase
MA06_RS16110	COG0531	amino acid
MA06_RS16115	COG2814	Major facilitator Superfamily
MA06_RS16120	COG1181	Belongs to the D-alanine--D-alanine ligase family
MA06_RS16125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MA06_RS16135	COG4294	response to UV
MA06_RS16145	COG0736	holo-[acyl-carrier-protein] synthase activity
MA06_RS16150	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MA06_RS16160	COG0864	Transcriptional regulator
MA06_RS16165	COG2337	Toxic component of a toxin-antitoxin (TA) module
MA06_RS16170	COG2183	response to ionizing radiation
MA06_RS16220	COG0544	peptidyl-prolyl cis-trans isomerase activity
MA06_RS16270	COG0802	atpase or kinase
MA06_RS16275	COG1214	PFAM Peptidase M22, glycoprotease
MA06_RS16280	COG0456	acetyltransferase
MA06_RS16290	COG0488	(ABC) transporter
MA06_RS16305	COG1266	CAAX protease self-immunity
MA06_RS16325	COG2252	PERMEase
MA06_RS16335	COG5002	protein histidine kinase activity
MA06_RS16375	COG0697	spore germination
MA06_RS16425	COG2205	protein histidine kinase activity
MA06_RS16430	COG0745	RESPONSE REGULATOR receiver
MA06_RS16470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MA06_RS16475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MA06_RS16480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MA06_RS16485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MA06_RS16490	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MA06_RS16495	COG0047	phosphoribosylformylglycinamidine synthase activity
MA06_RS16500	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MA06_RS16505	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MA06_RS16515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MA06_RS16520	COG0138	bifunctional purine biosynthesis protein purh
MA06_RS16525	COG0151	Belongs to the GarS family
MA06_RS16530	COG3829	transcription factor binding
MA06_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS16540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MA06_RS16545	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MA06_RS16550	COG0833	amino acid
MA06_RS16585	COG0210	DNA helicase
MA06_RS16595	COG4851	CamS sex pheromone cAM373 precursor
MA06_RS16605	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS16615	COG1335	isochorismatase
MA06_RS16630	COG0003	Pfam Anion-transporting ATPase
MA06_RS16635	COG1846	Transcriptional regulator
MA06_RS16640	COG4682	membrane
MA06_RS16660	COG1597	lipid kinase activity
MA06_RS16665	COG0546	phosphoglycolate phosphatase activity
MA06_RS16670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MA06_RS16685	COG2309	aminopeptidase activity
MA06_RS16710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS16720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MA06_RS16725	COG4807	Protein conserved in bacteria
MA06_RS16745	COG1473	amidohydrolase
MA06_RS16760	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MA06_RS16765	COG1349	DNA-binding transcription factor activity
MA06_RS16775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS16780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS16785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MA06_RS16790	COG0492	ferredoxin-NADP+ reductase activity
MA06_RS16800	COG0166	Belongs to the GPI family
MA06_RS16840	COG3541	Predicted nucleotidyltransferase
MA06_RS16845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MA06_RS16845	COG0723	plastoquinol--plastocyanin reductase activity
MA06_RS16855	COG0765	amino acid transport
MA06_RS16860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MA06_RS16865	COG1126	abc transporter atp-binding protein
MA06_RS16870	COG0277	FAD linked oxidase domain protein
MA06_RS16895	COG0549	Belongs to the carbamate kinase family
MA06_RS16900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MA06_RS16910	COG0366	Alpha amylase catalytic
MA06_RS16915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MA06_RS16915	COG2190	(PTS) system
MA06_RS16915	COG1263	PTS System
MA06_RS16935	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS16940	COG4605	iron ion homeostasis
MA06_RS16945	COG4604	ABC transporter, ATP-binding protein
MA06_RS16950	COG4607	ABC-type enterochelin transport system periplasmic component
MA06_RS16965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MA06_RS16970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MA06_RS16980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MA06_RS16990	COG1116	anion transmembrane transporter activity
MA06_RS16995	COG0488	(ABC) transporter
MA06_RS17005	COG1464	Belongs to the NlpA lipoprotein family
MA06_RS17010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MA06_RS17015	COG2011	ABC-type metal ion transport system permease component
MA06_RS17050	COG2270	Major facilitator Superfamily
MA06_RS17090	COG2310	stress, protein
MA06_RS17095	COG2310	stress, protein
MA06_RS17100	COG2310	stress, protein
MA06_RS17105	COG0861	Integral membrane protein TerC family
MA06_RS17115	COG3853	Toxic anion resistance protein (TelA)
MA06_RS17130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MA06_RS17145	COG2217	Heavy metal translocating P-type atpase
MA06_RS17150	COG0697	spore germination
MA06_RS17165	COG0681	Belongs to the peptidase S26 family
MA06_RS17180	COG0586	Pfam SNARE associated Golgi protein
MA06_RS17195	COG3871	stress protein (general stress protein 26)
MA06_RS17200	COG0387	Pfam Sodium calcium exchanger
MA06_RS17210	COG0535	radical SAM domain protein
MA06_RS17230	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MA06_RS17260	COG3829	transcription factor binding
MA06_RS17270	COG0833	amino acid
MA06_RS17300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MA06_RS17300	COG1263	PTS System
MA06_RS17305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MA06_RS17310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MA06_RS17320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MA06_RS17325	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MA06_RS17335	COG1228	amidohydrolase
MA06_RS17340	COG1090	epimerase
MA06_RS17345	COG2137	regulation of response to DNA damage stimulus
MA06_RS17365	COG1988	membrane-bound metal-dependent
MA06_RS17370	COG1194	a g-specific adenine glycosylase
MA06_RS17375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MA06_RS17395	COG3557	Belongs to the UPF0374 family
MA06_RS17400	COG1132	(ABC) transporter
MA06_RS17410	COG0070	glutamate synthase
MA06_RS17410	COG0069	glutamate synthase activity
MA06_RS17410	COG0067	glutamate synthase
MA06_RS17415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MA06_RS17420	COG4555	ABC transporter
MA06_RS17440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MA06_RS17445	COG0735	belongs to the Fur family
MA06_RS17560	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MA06_RS17565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MA06_RS17585	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MA06_RS17590	COG2766	serine protein kinase
MA06_RS17600	COG1585	Membrane protein implicated in regulation of membrane protease activity
MA06_RS17605	COG2268	Band 7 protein
MA06_RS17610	COG0745	RESPONSE REGULATOR receiver
MA06_RS17615	COG5002	protein histidine kinase activity
MA06_RS17635	COG2217	Heavy metal translocating P-type atpase
MA06_RS17650	COG4565	transcriptional regulatory protein
MA06_RS17655	COG2851	Citrate transporter
MA06_RS17680	COG1131	(ABC) transporter
MA06_RS17705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS17710	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MA06_RS17720	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MA06_RS17725	COG3842	ATPase activity
MA06_RS17730	COG1175	transmembrane transport
MA06_RS17735	COG0395	ABC-type sugar transport system, permease component
MA06_RS17745	COG0745	RESPONSE REGULATOR receiver
MA06_RS17750	COG5002	protein histidine kinase activity
MA06_RS17760	COG4990	cell redox homeostasis
MA06_RS17765	COG3290	protein histidine kinase activity
MA06_RS17770	COG4565	transcriptional regulatory protein
MA06_RS17775	COG3493	citrate carrier protein
MA06_RS17780	COG0281	malic enzyme
MA06_RS17790	COG0697	spore germination
MA06_RS17795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS17805	COG5002	protein histidine kinase activity
MA06_RS17810	COG0745	RESPONSE REGULATOR receiver
MA06_RS17820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MA06_RS17825	COG3383	formate dehydrogenase (NAD+) activity
MA06_RS17830	COG2427	Protein of unknown function (DUF1641)
MA06_RS17845	COG0531	amino acid
MA06_RS17855	COG0640	Transcriptional regulator
MA06_RS17860	COG2217	Heavy metal translocating P-type atpase
MA06_RS17865	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MA06_RS17875	COG3227	Zinc metalloprotease (Elastase)
MA06_RS17885	COG1937	Protein conserved in bacteria
MA06_RS17890	COG2217	Heavy metal translocating P-type atpase
MA06_RS17910	COG2720	vancomycin resistance protein
MA06_RS17915	COG1316	TRANSCRIPTIONal
MA06_RS17920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS17925	COG0346	lactoylglutathione lyase activity
MA06_RS17930	COG1253	flavin adenine dinucleotide binding
MA06_RS17935	COG1027	Aspartate ammonia-lyase
MA06_RS17940	COG1620	l-lactate permease
MA06_RS17955	COG3104	oligopeptide transport
MA06_RS17960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MA06_RS17965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS17970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MA06_RS17980	COG0500	methyltransferase
MA06_RS17985	COG0156	8-amino-7-oxononanoate synthase activity
MA06_RS18000	COG4548	von Willebrand factor, type A
MA06_RS18005	COG0714	Associated with various cellular activities
MA06_RS18030	COG0531	amino acid
MA06_RS18035	COG2188	Transcriptional regulator
MA06_RS18040	COG1263	PTS System
MA06_RS18040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MA06_RS18045	COG0366	Alpha amylase catalytic
MA06_RS18050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MA06_RS18055	COG1115	amino acid carrier protein
MA06_RS18060	COG1126	abc transporter atp-binding protein
MA06_RS18065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MA06_RS18070	COG0765	amino acid transport
MA06_RS18075	COG0765	amino acid transport
MA06_RS18080	COG0833	amino acid
MA06_RS18090	COG5002	protein histidine kinase activity
MA06_RS18110	COG0589	response to stress
MA06_RS18115	COG2271	Major facilitator Superfamily
MA06_RS18120	COG1846	Transcriptional regulator
MA06_RS18125	COG0477	Major facilitator Superfamily
MA06_RS18130	COG1609	Transcriptional regulator
MA06_RS18135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MA06_RS18150	COG1172	Belongs to the binding-protein-dependent transport system permease family
MA06_RS18155	COG1879	ABC-type sugar transport system periplasmic component
MA06_RS18160	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MA06_RS18170	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS18180	COG1063	alcohol dehydrogenase
MA06_RS18185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MA06_RS18200	COG0277	FAD linked oxidase domain protein
MA06_RS18215	COG1388	LysM domain
MA06_RS18215	COG3584	3D domain protein
MA06_RS18220	COG1476	TRANSCRIPTIONal
MA06_RS18230	COG3391	amine dehydrogenase activity
MA06_RS18240	COG3104	oligopeptide transport
MA06_RS18265	COG1113	amino acid transport
MA06_RS18270	COG2252	PERMEase
MA06_RS18285	COG2153	protein acetylation
MA06_RS18295	COG0475	glutathione-regulated potassium exporter activity
MA06_RS18295	COG0569	domain protein
MA06_RS18305	COG1845	cytochrome c oxidase, subunit III
MA06_RS18320	COG0833	amino acid
MA06_RS18325	COG4990	cell redox homeostasis
MA06_RS18335	COG0697	spore germination
MA06_RS18340	COG0531	amino acid
MA06_RS18350	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MA06_RS18355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MA06_RS18360	COG1918	ferrous iron import across plasma membrane
MA06_RS18360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
MA06_RS18365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MA06_RS18370	COG0573	inorganic phosphate transmembrane transporter activity
MA06_RS18375	COG0581	inorganic phosphate transmembrane transporter activity
MA06_RS18385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MA06_RS18425	COG0544	peptidyl-prolyl cis-trans isomerase activity
MA06_RS18505	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
MA06_RS18525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MA06_RS18530	COG1116	anion transmembrane transporter activity
MA06_RS18535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MA06_RS18540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MA06_RS18545	COG0352	thiamine-phosphate diphosphorylase activity
MA06_RS18550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MA06_RS18555	COG2104	thiamine diphosphate biosynthetic process
MA06_RS18565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MA06_RS18570	COG0351	phosphomethylpyrimidine kinase
MA06_RS18595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MA06_RS18610	COG2205	protein histidine kinase activity
MA06_RS18620	COG1846	Transcriptional regulator
MA06_RS18630	COG2252	PERMEase
MA06_RS18635	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS18640	COG1376	ErfK ybiS ycfS ynhG family protein
MA06_RS18695	COG0778	Nitroreductase
MA06_RS18700	COG2719	SpoVR family
MA06_RS18710	COG0446	pyridine nucleotide-disulphide oxidoreductase
MA06_RS18715	COG1937	Protein conserved in bacteria
MA06_RS18720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MA06_RS18720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MA06_RS18725	COG0425	Belongs to the sulfur carrier protein TusA family
MA06_RS18730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MA06_RS18735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MA06_RS18740	COG2210	Belongs to the sulfur carrier protein TusA family
MA06_RS18745	COG0730	response to heat
MA06_RS18755	COG1316	TRANSCRIPTIONal
MA06_RS18760	COG1283	sodium-dependent phosphate transmembrane transporter activity
MA06_RS18770	COG2814	Major facilitator Superfamily
MA06_RS18785	COG0577	efflux transmembrane transporter activity
MA06_RS18790	COG1136	(ABC) transporter
MA06_RS18800	COG5522	Integral membrane protein (intg_mem_TP0381)
MA06_RS18815	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS18820	COG3546	catalase activity
MA06_RS18855	COG0586	Pfam SNARE associated Golgi protein
MA06_RS18870	COG0531	amino acid
MA06_RS18875	COG0475	glutathione-regulated potassium exporter activity
MA06_RS18885	COG1737	Transcriptional regulator
MA06_RS18890	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MA06_RS18895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MA06_RS18895	COG1263	PTS System
MA06_RS18925	COG0697	spore germination
MA06_RS18930	COG1522	sequence-specific DNA binding
MA06_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS18945	COG1733	regulation of RNA biosynthetic process
MA06_RS18955	COG2249	NAD(P)H dehydrogenase (quinone) activity
MA06_RS18960	COG4533	DNA binding
MA06_RS18965	COG2211	Major facilitator Superfamily
MA06_RS18975	COG1191	sigma factor activity
MA06_RS19000	COG0531	amino acid
MA06_RS19005	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS19010	COG1132	(ABC) transporter
MA06_RS19015	COG1132	(ABC) transporter
MA06_RS19020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MA06_RS19025	COG0765	amino acid transport
MA06_RS19030	COG1126	abc transporter atp-binding protein
MA06_RS19045	COG0189	ligase activity
MA06_RS19050	COG4399	Belongs to the UPF0754 family
MA06_RS19055	COG3679	Belongs to the UPF0342 family
MA06_RS19060	COG0028	Belongs to the TPP enzyme family
MA06_RS19065	COG3527	Alpha-acetolactate decarboxylase
MA06_RS19075	COG0561	phosphatase activity
MA06_RS19080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MA06_RS19100	COG0659	secondary active sulfate transmembrane transporter activity
MA06_RS19110	COG1024	Enoyl-CoA hydratase
MA06_RS19125	COG1363	Peptidase, m42
MA06_RS19135	COG0814	amino acid
MA06_RS19140	COG0697	spore germination
MA06_RS19150	COG1113	amino acid transport
MA06_RS19155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MA06_RS19180	COG0579	oxidoreductase
MA06_RS19240	COG3290	protein histidine kinase activity
MA06_RS19240	COG3829	transcription factor binding
MA06_RS19250	COG0477	Major facilitator Superfamily
MA06_RS19255	COG3290	protein histidine kinase activity
MA06_RS19260	COG4565	transcriptional regulatory protein
MA06_RS19265	COG3181	Tripartite tricarboxylate transporter family receptor
MA06_RS19345	COG1061	Type III restriction enzyme res subunit
MA06_RS19350	COG2610	gluconate transmembrane transporter activity
MA06_RS19365	COG0305	Participates in initiation and elongation during chromosome replication
MA06_RS19385	COG1215	transferase activity, transferring glycosyl groups
MA06_RS19400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MA06_RS19405	COG0489	protein tyrosine kinase activity
MA06_RS19430	COG0305	Participates in initiation and elongation during chromosome replication
MA06_RS19435	COG2271	Major facilitator Superfamily
MA06_RS19440	COG0277	FAD linked oxidase domain protein
MA06_RS19445	COG1619	proteins homologs of microcin C7 resistance protein MccF
MA06_RS19455	COG1785	Belongs to the alkaline phosphatase family
MA06_RS19485	COG0346	lactoylglutathione lyase activity
MA06_RS19495	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MA06_RS19495	COG2508	Transcriptional regulator
MA06_RS19515	COG2720	vancomycin resistance protein
MA06_RS19555	COG1132	(ABC) transporter
MA06_RS19565	COG4585	Histidine kinase
MA06_RS19570	COG2197	response regulator
MA06_RS19590	COG2124	cytochrome p450
MA06_RS19610	COG0083	homoserine kinase activity
MA06_RS19645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MA06_RS19655	COG2814	Major facilitator Superfamily
MA06_RS19665	COG0657	acetylesterase activity
MA06_RS19695	COG0531	amino acid
MA06_RS19710	COG0531	amino acid
MA06_RS19715	COG1760	l-serine dehydratase
MA06_RS19720	COG1760	l-serine dehydratase
MA06_RS19725	COG0814	amino acid
MA06_RS19745	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
MA06_RS19750	COG1335	isochorismatase
MA06_RS19755	COG3813	Protein conserved in bacteria
MA06_RS19760	COG1522	sequence-specific DNA binding
MA06_RS19820	COG0745	RESPONSE REGULATOR receiver
MA06_RS19830	COG4991	sh3 domain protein
MA06_RS19830	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS19830	COG3103	Sh3 type 3 domain protein
MA06_RS19845	COG5002	protein histidine kinase activity
MA06_RS19870	COG0395	ABC-type sugar transport system, permease component
MA06_RS19875	COG1175	transmembrane transport
MA06_RS19940	COG2801	Transposase and inactivated derivatives
MA06_RS19955	COG2376	Dihydroxyacetone kinase
MA06_RS19980	COG0577	efflux transmembrane transporter activity
MA06_RS19985	COG1136	(ABC) transporter
MA06_RS20010	COG5002	protein histidine kinase activity
MA06_RS20015	COG0745	RESPONSE REGULATOR receiver
MA06_RS20030	COG2186	Transcriptional regulator
MA06_RS20060	COG0657	acetylesterase activity
MA06_RS20065	COG2132	Multicopper oxidase
MA06_RS20075	COG0789	Transcriptional regulator
MA06_RS20075	COG4978	Transcriptional regulator
MA06_RS20105	COG0420	3'-5' exonuclease activity
MA06_RS20110	COG4717	serine-type aminopeptidase activity
MA06_RS20115	COG3481	metal-dependent phosphohydrolase, HD sub domain
MA06_RS20135	COG0457	Tetratricopeptide repeat
MA06_RS20145	COG2267	carboxylic ester hydrolase activity
MA06_RS20160	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MA06_RS20170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MA06_RS20175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MA06_RS20180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MA06_RS20205	COG4980	gas vesicle protein
MA06_RS20215	COG0537	adenosine 5'-monophosphoramidase activity
MA06_RS20220	COG1131	(ABC) transporter
MA06_RS20225	COG4473	ABC transporter
MA06_RS20240	COG0596	Alpha beta hydrolase
MA06_RS20245	COG0745	RESPONSE REGULATOR receiver
MA06_RS20250	COG0642	Histidine kinase
MA06_RS20260	COG3402	PFAM membrane-flanked domain
MA06_RS20265	COG3428	Bacterial PH domain
MA06_RS20275	COG0346	lactoylglutathione lyase activity
MA06_RS20280	COG0531	amino acid
MA06_RS20315	COG3402	PFAM membrane-flanked domain
MA06_RS20320	COG3428	Bacterial PH domain
MA06_RS20330	COG2329	Antibiotic biosynthesis monooxygenase
MA06_RS20335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MA06_RS20340	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MA06_RS20345	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MA06_RS20350	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MA06_RS20360	COG1942	4-Oxalocrotonate Tautomerase
MA06_RS20365	COG0583	DNA-binding transcription factor activity
MA06_RS20370	COG0583	DNA-binding transcription factor activity
MA06_RS20375	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS20390	COG1309	transcriptional regulator
MA06_RS20395	COG1511	domain protein
MA06_RS20410	COG2378	regulation of single-species biofilm formation
MA06_RS20415	COG1609	Transcriptional regulator
MA06_RS20420	COG1234	tRNA 3'-trailer cleavage
MA06_RS20425	COG0095	Lipoate-protein ligase
MA06_RS20430	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS20440	COG1408	metallophosphoesterase
MA06_RS20450	COG2207	Transcriptional regulator
MA06_RS20450	COG3708	Transcriptional regulator
MA06_RS20455	COG2205	protein histidine kinase activity
MA06_RS20460	COG0745	RESPONSE REGULATOR receiver
MA06_RS20485	COG0501	Belongs to the peptidase M48B family
MA06_RS20505	COG0697	spore germination
MA06_RS20510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MA06_RS20515	COG2224	Isocitrate lyase
MA06_RS20525	COG1278	Cold shock
MA06_RS20530	COG4903	ComK protein
MA06_RS20540	COG5002	protein histidine kinase activity
MA06_RS20545	COG0398	Pfam SNARE associated Golgi protein
MA06_RS20605	COG0179	Fumarylacetoacetate (FAA) hydrolase
MA06_RS20630	COG0367	asparagine synthase
MA06_RS20640	COG3773	Cell wall hydrolase
MA06_RS20650	COG0753	catalase activity
MA06_RS20655	COG0004	ammonium transporteR
MA06_RS20675	COG2996	Protein conserved in bacteria
MA06_RS20685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS20700	COG0561	phosphatase activity
MA06_RS20720	COG2267	carboxylic ester hydrolase activity
MA06_RS20735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MA06_RS20740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MA06_RS20745	COG5504	Zn-dependent protease
MA06_RS20755	COG0180	Tryptophanyl-tRNA synthetase
MA06_RS20775	COG4166	transmembrane transport
MA06_RS20780	COG0601	transmembrane transport
MA06_RS20785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MA06_RS20790	COG0444	Belongs to the ABC transporter superfamily
MA06_RS20795	COG4608	Belongs to the ABC transporter superfamily
MA06_RS20800	COG0534	Mate efflux family protein
MA06_RS20805	COG4166	transmembrane transport
MA06_RS20820	COG0861	Integral membrane protein TerC family
MA06_RS20825	COG4862	establishment of competence for transformation
MA06_RS20835	COG4469	Competence protein
MA06_RS20840	COG1164	Oligoendopeptidase f
MA06_RS20850	COG2346	COG2346, Truncated hemoglobins
MA06_RS20855	COG4116	CYTH
MA06_RS20865	COG2357	RelA SpoT domain protein
MA06_RS20875	COG0564	pseudouridine synthase activity
MA06_RS20880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MA06_RS20885	COG0772	Belongs to the SEDS family
MA06_RS20900	COG2089	acid synthase
MA06_RS20915	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
MA06_RS20920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MA06_RS20925	COG1086	Polysaccharide biosynthesis protein
MA06_RS20930	COG1216	Glycosyl transferase, family 2
MA06_RS20930	COG0463	Glycosyl transferase, family 2
MA06_RS20940	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MA06_RS20945	COG4641	Protein conserved in bacteria
MA06_RS20965	COG0463	Glycosyl transferase, family 2
MA06_RS20980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MA06_RS21000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MA06_RS21015	COG1091	dTDP-4-dehydrorhamnose reductase activity
MA06_RS21065	COG2153	protein acetylation
MA06_RS21075	COG2382	esterase
MA06_RS21095	COG5492	domain, Protein
MA06_RS21100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MA06_RS21105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MA06_RS21110	COG0512	Glutamine amidotransferase of anthranilate synthase
MA06_RS21115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MA06_RS21120	COG0134	indole-3-glycerol-phosphate synthase activity
MA06_RS21130	COG0133	tryptophan synthase activity
MA06_RS21135	COG0159	tryptophan synthase activity
MA06_RS21155	COG1620	l-lactate permease
MA06_RS21160	COG5634	Uncharacterized conserved protein (DUF2278)
MA06_RS21215	COG0508	dehydrogenase complex catalyzes the overall conversion of
MA06_RS21260	COG0641	radical SAM
MA06_RS21300	COG0641	radical SAM
MA06_RS21360	COG0457	Tetratricopeptide repeat
MA06_RS21375	COG4974	Belongs to the 'phage' integrase family
MA06_RS21395	COG1686	Belongs to the peptidase S11 family
MA06_RS21400	COG0681	Belongs to the peptidase S26 family
MA06_RS21440	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS21450	COG1176	ABC-type spermidine putrescine transport system, permease component I
MA06_RS21455	COG1177	transmembrane transport
MA06_RS21460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MA06_RS21465	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS21470	COG2409	Drug exporters of the RND superfamily
MA06_RS21480	COG0564	pseudouridine synthase activity
MA06_RS21490	COG2340	Cysteine-rich secretory protein family
MA06_RS21495	COG0247	lactate metabolic process
MA06_RS21500	COG0277	FAD linked oxidase domain protein
MA06_RS21505	COG3835	regulator
MA06_RS21515	COG0745	RESPONSE REGULATOR receiver
MA06_RS21520	COG5002	protein histidine kinase activity
MA06_RS21525	COG2186	Transcriptional regulator
MA06_RS21530	COG0247	lactate metabolic process
MA06_RS21545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
MA06_RS21555	COG2116	formate transmembrane transporter activity
MA06_RS21560	COG0861	Integral membrane protein TerC family
MA06_RS21565	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MA06_RS21575	COG2030	dehydratase
MA06_RS21595	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS21600	COG3243	poly(R)-hydroxyalkanoic acid synthase
MA06_RS21610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MA06_RS21635	COG1349	DNA-binding transcription factor activity
MA06_RS21640	COG0235	Class ii aldolase
MA06_RS21650	COG2861	carbohydrate metabolic process
MA06_RS21660	COG3852	Histidine kinase
MA06_RS21665	COG1846	Transcriptional regulator
MA06_RS21675	COG2318	DinB family
MA06_RS21685	COG5002	protein histidine kinase activity
MA06_RS21695	COG0720	synthase
MA06_RS21705	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MA06_RS21710	COG4873	Protein conserved in bacteria
MA06_RS21725	COG0456	acetyltransferase
MA06_RS21740	COG1780	Probably involved in ribonucleotide reductase function
MA06_RS21745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MA06_RS21755	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MA06_RS21760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MA06_RS21765	COG0531	amino acid
MA06_RS21770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MA06_RS21785	COG3290	protein histidine kinase activity
MA06_RS21785	COG3829	transcription factor binding
MA06_RS21790	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS21800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MA06_RS21805	COG1960	acyl-CoA dehydrogenase activity
MA06_RS21810	COG1725	Transcriptional regulator
MA06_RS21815	COG1131	(ABC) transporter
MA06_RS21825	COG1131	(ABC) transporter
MA06_RS21830	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
MA06_RS21835	COG1115	amino acid carrier protein
MA06_RS21850	COG1522	sequence-specific DNA binding
MA06_RS21860	COG1335	isochorismatase
MA06_RS21870	COG1619	proteins homologs of microcin C7 resistance protein MccF
MA06_RS21875	COG2070	2-Nitropropane dioxygenase
MA06_RS21880	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MA06_RS21890	COG1696	Membrane protein involved in D-alanine export
MA06_RS21910	COG0716	FMN binding
MA06_RS21940	COG0534	Mate efflux family protein
MA06_RS21960	COG1846	Transcriptional regulator
MA06_RS21970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MA06_RS21980	COG3874	Sporulation protein YtfJ
MA06_RS22000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MA06_RS22005	COG0028	Belongs to the TPP enzyme family
MA06_RS22010	COG0440	acetolactate synthase activity
MA06_RS22015	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MA06_RS22020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MA06_RS22055	COG0131	Imidazoleglycerol-phosphate dehydratase
MA06_RS22080	COG0140	phosphoribosyl-ATP diphosphatase activity
MA06_RS22085	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MA06_RS22095	COG1183	phosphatidylcholine synthase activity
MA06_RS22100	COG1368	sulfuric ester hydrolase activity
MA06_RS22110	COG0019	diaminopimelate decarboxylase activity
MA06_RS22120	COG2046	Belongs to the sulfate adenylyltransferase family
MA06_RS22125	COG0529	Catalyzes the synthesis of activated sulfate
MA06_RS22130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MA06_RS22155	COG0733	neurotransmitter:sodium symporter activity
MA06_RS22175	COG1757	Na H antiporter
MA06_RS22190	COG4758	membrane
MA06_RS22195	COG4585	Histidine kinase
MA06_RS22200	COG2197	response regulator
MA06_RS22210	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS22215	COG4085	toxin activity
MA06_RS22215	COG1525	nuclease
MA06_RS22215	COG0737	Belongs to the 5'-nucleotidase family
MA06_RS22225	COG2226	methyltransferase
MA06_RS22255	COG0730	response to heat
MA06_RS22260	COG0306	phosphate transporter
MA06_RS22265	COG1392	Phosphate transport regulator
MA06_RS22270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MA06_RS22280	COG3852	Histidine kinase
MA06_RS22285	COG1801	Protein of unknown function DUF72
MA06_RS22300	COG0582	viral genome integration into host DNA
MA06_RS22305	COG5002	protein histidine kinase activity
MA06_RS22320	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MA06_RS22320	COG0392	lysyltransferase activity
MA06_RS22335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MA06_RS22340	COG1686	Belongs to the peptidase S11 family
MA06_RS22345	COG2715	membrane protein required for spore maturation
MA06_RS22350	COG0700	Nucleoside recognition
MA06_RS22355	COG1187	pseudouridine synthase activity
MA06_RS22365	COG1333	cytochrome c biogenesis protein
MA06_RS22370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MA06_RS22375	COG0745	RESPONSE REGULATOR receiver
MA06_RS22380	COG5002	protein histidine kinase activity
MA06_RS22385	COG2096	Adenosyltransferase
MA06_RS22390	COG4942	peptidase
MA06_RS22405	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MA06_RS22415	COG4955	Helix-turn-helix domain
MA06_RS22420	COG0514	ATP-dependent DNA helicase (RecQ)
MA06_RS22425	COG1266	CAAX protease self-immunity
MA06_RS22435	COG1408	metallophosphoesterase
MA06_RS22445	COG4862	establishment of competence for transformation
MA06_RS22450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MA06_RS22470	COG0492	ferredoxin-NADP+ reductase activity
MA06_RS22500	COG2197	response regulator
MA06_RS22550	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MA06_RS22565	COG0142	geranyltranstransferase activity
MA06_RS22570	COG2226	methyltransferase
MA06_RS22575	COG0142	geranyltranstransferase activity
MA06_RS22585	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MA06_RS22605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MA06_RS22610	COG0457	Tetratricopeptide repeat
MA06_RS22630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MA06_RS22635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MA06_RS22635	COG2010	Cytochrome c
MA06_RS22640	COG4347	Protein of unknown function (DUF1405)
MA06_RS22655	COG2738	Putative neutral zinc metallopeptidase
MA06_RS22665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS22670	COG1694	Mazg nucleotide pyrophosphohydrolase
MA06_RS22675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MA06_RS22685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MA06_RS22690	COG0438	transferase activity, transferring glycosyl groups
MA06_RS22695	COG0617	tRNA 3'-terminal CCA addition
MA06_RS22720	COG1199	ATP-dependent helicase activity
MA06_RS22720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MA06_RS22735	COG3935	DnaD domain protein
MA06_RS22740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MA06_RS22750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MA06_RS22750	COG4499	WXG100 protein secretion system (Wss), protein YukC
MA06_RS22795	COG3599	regulation of cell shape
MA06_RS22800	COG0116	Belongs to the methyltransferase superfamily
MA06_RS22810	COG1199	ATP-dependent helicase activity
MA06_RS22815	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MA06_RS22830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MA06_RS22835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MA06_RS22840	COG0024	Methionine aminopeptidase
MA06_RS22850	COG2233	PERMEase
MA06_RS22860	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MA06_RS22870	COG0456	acetyltransferase
MA06_RS22900	COG3766	membrane
MA06_RS22910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MA06_RS22920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MA06_RS22925	COG0454	-acetyltransferase
MA06_RS22940	COG0697	spore germination
MA06_RS22945	COG0328	RNA-DNA hybrid ribonuclease activity
MA06_RS22960	COG0328	RNA-DNA hybrid ribonuclease activity
MA06_RS22970	COG1278	Cold shock
MA06_RS22975	COG3403	YqcI/YcgG family
MA06_RS22980	COG1280	lysine exporter protein (LysE YggA)
MA06_RS23005	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MA06_RS23010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MA06_RS23015	COG0475	glutathione-regulated potassium exporter activity
MA06_RS23020	COG4978	Transcriptional regulator
MA06_RS23020	COG0789	Transcriptional regulator
MA06_RS23030	COG2323	membrane
MA06_RS23035	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MA06_RS23105	COG0494	nUDIX hydrolase
MA06_RS23130	COG0412	Dienelactone hydrolase
MA06_RS23135	COG2329	Antibiotic biosynthesis monooxygenase
MA06_RS23180	COG0406	alpha-ribazole phosphatase activity
MA06_RS23200	COG1846	Transcriptional regulator
MA06_RS23235	COG1802	Transcriptional regulator
MA06_RS23240	COG0697	spore germination
MA06_RS23250	COG0523	cobalamin synthesis protein
MA06_RS23255	COG0701	Predicted permease
MA06_RS23260	COG3689	TIGRFAM TIGR03943 family protein
MA06_RS23265	COG1335	isochorismatase
MA06_RS23270	COG1757	Na H antiporter
MA06_RS23275	COG0861	Integral membrane protein TerC family
MA06_RS23290	COG1819	glycosyl
MA06_RS23300	COG0534	Mate efflux family protein
MA06_RS23310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS23320	COG3048	D-serine ammonia-lyase activity
MA06_RS23325	COG2733	membrane
MA06_RS23345	COG1595	DNA-templated transcription, initiation
MA06_RS23350	COG2197	response regulator
MA06_RS23360	COG1131	(ABC) transporter
MA06_RS23380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MA06_RS23395	COG0528	UMP kinase activity
MA06_RS23405	COG1027	Aspartate ammonia-lyase
MA06_RS23410	COG0281	malic enzyme
MA06_RS23415	COG4191	Histidine kinase
MA06_RS23420	COG0784	Response regulator, receiver
MA06_RS23435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MA06_RS23440	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MA06_RS23445	COG2502	aspartate--ammonia ligase
MA06_RS23455	COG1131	(ABC) transporter
MA06_RS23470	COG0109	protoheme IX farnesyltransferase activity
MA06_RS23475	COG2205	protein histidine kinase activity
MA06_RS23480	COG0745	RESPONSE REGULATOR receiver
MA06_RS23525	COG1695	Transcriptional regulator
MA06_RS23540	COG0586	Pfam SNARE associated Golgi protein
MA06_RS23545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS23560	COG0477	Major facilitator Superfamily
MA06_RS23575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MA06_RS23580	COG0488	(ABC) transporter
MA06_RS23585	COG2223	nitrite transmembrane transporter activity
MA06_RS23590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MA06_RS23595	COG2244	polysaccharide biosynthetic process
MA06_RS23600	COG0733	neurotransmitter:sodium symporter activity
MA06_RS23615	COG5566	PFAM Mor transcription activator
MA06_RS23635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MA06_RS23645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MA06_RS23650	COG0028	Belongs to the TPP enzyme family
MA06_RS23655	COG0440	acetolactate synthase activity
MA06_RS23665	COG0129	dihydroxy-acid dehydratase activity
MA06_RS23670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MA06_RS23680	COG1811	Na channel or pump
MA06_RS23715	COG2814	Major facilitator Superfamily
MA06_RS23755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MA06_RS23765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MA06_RS23790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MA06_RS23800	COG3384	dioxygenase
MA06_RS23830	COG4166	transmembrane transport
MA06_RS23835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS23855	COG1914	H( )-stimulated, divalent metal cation uptake system
MA06_RS23860	COG1054	Belongs to the UPF0176 family
MA06_RS23870	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS23875	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MA06_RS23885	COG5002	protein histidine kinase activity
MA06_RS23890	COG0531	amino acid
MA06_RS23895	COG4585	Histidine kinase
MA06_RS23900	COG2197	response regulator
MA06_RS23930	COG2390	Transcriptional regulator
MA06_RS23935	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MA06_RS23940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MA06_RS23945	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MA06_RS23970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MA06_RS23975	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MA06_RS23985	COG0583	DNA-binding transcription factor activity
MA06_RS23990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS23995	COG1181	Belongs to the D-alanine--D-alanine ligase family
MA06_RS24000	COG0189	ligase activity
MA06_RS24005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MA06_RS24010	COG3383	formate dehydrogenase (NAD+) activity
MA06_RS24015	COG2427	Protein of unknown function (DUF1641)
MA06_RS24020	COG5609	conserved protein (DUF2294)
MA06_RS24025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MA06_RS24035	COG2116	formate transmembrane transporter activity
MA06_RS24040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MA06_RS24045	COG0303	'Molybdopterin
MA06_RS24050	COG0314	molybdopterin synthase activity
MA06_RS24060	COG0489	protein tyrosine kinase activity
MA06_RS24080	COG0659	secondary active sulfate transmembrane transporter activity
MA06_RS24090	COG2824	Alkylphosphonate utilization operon protein PhnA
MA06_RS24095	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS24105	COG2372	response to copper ion
MA06_RS24105	COG1276	copper resistance
MA06_RS24120	COG0697	spore germination
MA06_RS24125	COG0583	DNA-binding transcription factor activity
MA06_RS24130	COG1959	2 iron, 2 sulfur cluster binding
MA06_RS24135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MA06_RS24140	COG0778	Nitroreductase
MA06_RS24150	COG0628	permease
MA06_RS24160	COG0523	cobalamin synthesis protein
MA06_RS24225	COG1686	Belongs to the peptidase S11 family
MA06_RS24245	COG1378	Sugar-specific transcriptional regulator TrmB
MA06_RS24250	COG0791	NLP P60 protein
MA06_RS24250	COG1388	LysM domain
MA06_RS24260	COG1132	(ABC) transporter
MA06_RS24265	COG0300	oxidoreductase activity
MA06_RS24280	COG1999	signal sequence binding
MA06_RS24295	COG2072	flavoprotein involved in K transport
MA06_RS24300	COG2072	flavoprotein involved in K transport
MA06_RS24305	COG2072	flavoprotein involved in K transport
MA06_RS24325	COG1999	signal sequence binding
MA06_RS24330	COG0640	Transcriptional regulator
MA06_RS24335	COG0798	PFAM Bile acid sodium symporter
MA06_RS24385	COG0460	homoserine dehydrogenase
MA06_RS24395	COG0083	homoserine kinase activity
MA06_RS24405	COG1316	TRANSCRIPTIONal
MA06_RS24420	COG1285	pathogenesis
MA06_RS24440	COG2814	Major facilitator Superfamily
MA06_RS24445	COG1279	arginine transmembrane transporter activity
MA06_RS24450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS24455	COG2720	vancomycin resistance protein
MA06_RS24460	COG1752	Esterase of the alpha-beta hydrolase superfamily
MA06_RS24480	COG0494	nUDIX hydrolase
MA06_RS24495	COG0577	efflux transmembrane transporter activity
MA06_RS24505	COG1404	Belongs to the peptidase S8 family
MA06_RS24510	COG0640	Transcriptional regulator
MA06_RS24515	COG0667	Aldo Keto reductase
MA06_RS24555	COG3949	Membrane
MA06_RS24560	COG0783	Belongs to the Dps family
MA06_RS24575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MA06_RS24585	COG1231	oxidoreductase activity
MA06_RS24600	COG4989	oxidoreductase activity
MA06_RS24605	COG0523	cobalamin synthesis protein
MA06_RS24620	COG0803	Belongs to the bacterial solute-binding protein 9 family
MA06_RS24625	COG0702	epimerase
MA06_RS24635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MA06_RS24645	COG4166	transmembrane transport
MA06_RS24670	COG5337	Spore coat protein CotH
MA06_RS24680	COG1051	belongs to the nudix hydrolase family
MA06_RS24685	COG0586	Pfam SNARE associated Golgi protein
MA06_RS24690	COG2244	polysaccharide biosynthetic process
MA06_RS24700	COG0701	Predicted permease
MA06_RS24705	COG3689	TIGRFAM TIGR03943 family protein
MA06_RS24710	COG1607	acyl-coa hydrolase
MA06_RS24715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MA06_RS24735	COG0702	epimerase
MA06_RS24740	COG2839	Protein conserved in bacteria
MA06_RS24745	COG1253	flavin adenine dinucleotide binding
MA06_RS24760	COG1114	Component of the transport system for branched-chain amino acids
MA06_RS24765	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MA06_RS24780	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS24790	COG1876	peptidase activity
MA06_RS24805	COG2211	Major facilitator Superfamily
MA06_RS24820	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS24825	COG2368	4-hydroxyphenylacetate
MA06_RS24835	COG0196	riboflavin kinase activity
MA06_RS24850	COG0251	oxidation-reduction process
MA06_RS24860	COG3971	2-oxopent-4-enoate hydratase activity
MA06_RS24885	COG1846	Transcriptional regulator
MA06_RS24890	COG2814	Major facilitator Superfamily
MA06_RS24895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MA06_RS24910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MA06_RS24915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS24980	COG4499	WXG100 protein secretion system (Wss), protein YukC
MA06_RS25060	COG2002	toxin-antitoxin pair type II binding
MA06_RS25070	COG2801	Transposase and inactivated derivatives
MA06_RS25130	COG3874	Sporulation protein YtfJ
MA06_RS25155	COG2226	methyltransferase
MA06_RS25185	COG1595	DNA-templated transcription, initiation
MA06_RS25205	COG0386	Belongs to the glutathione peroxidase family
MA06_RS25210	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MA06_RS25225	COG5632	N-Acetylmuramoyl-L-alanine amidase
MA06_RS25355	COG1418	mRNA catabolic process
MA06_RS25360	COG0488	(ABC) transporter
MA06_RS25370	COG0629	single-stranded DNA binding
MA06_RS25390	COG1413	lyase activity
MA06_RS25405	COG2521	methyltransferase
MA06_RS25405	COG2136	Putative SAM-dependent methyltransferase
MA06_RS25410	COG0018	arginyl-trna synthetase
MA06_RS25425	COG3961	Belongs to the TPP enzyme family
MA06_RS25460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MA06_RS25480	COG0488	(ABC) transporter
MA06_RS25495	COG1307	EDD domain protein, DegV family
MA06_RS25535	COG1309	transcriptional regulator
MA06_RS25555	COG0017	Asparaginyl-tRNA synthetase
MA06_RS25560	COG0733	neurotransmitter:sodium symporter activity
MA06_RS25575	COG1131	(ABC) transporter
MA06_RS25580	COG2197	response regulator
MA06_RS25585	COG0596	Alpha beta hydrolase
MA06_RS25605	COG2610	gluconate transmembrane transporter activity
MA06_RS25610	COG1454	alcohol dehydrogenase
MA06_RS25615	COG2610	gluconate transmembrane transporter activity
MA06_RS25620	COG1794	racemase activity, acting on amino acids and derivatives
MA06_RS25630	COG0456	acetyltransferase
MA06_RS25635	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MA06_RS25645	COG1131	(ABC) transporter
MA06_RS25660	COG0546	phosphoglycolate phosphatase activity
MA06_RS25670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MA06_RS25685	COG0768	penicillin binding
MA06_RS25700	COG1272	protein, Hemolysin III
MA06_RS25705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MA06_RS25710	COG0805	protein transport
MA06_RS25730	COG1999	signal sequence binding
MA06_RS25740	COG0367	asparagine synthase
MA06_RS25755	COG0860	N-Acetylmuramoyl-L-alanine amidase
MA06_RS25760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MA06_RS25765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MA06_RS25780	COG3708	Transcriptional regulator
MA06_RS25780	COG2207	Transcriptional regulator
MA06_RS25785	COG1335	isochorismatase
MA06_RS25790	COG4585	Histidine kinase
MA06_RS25790	COG2203	Gaf domain
MA06_RS25795	COG2197	response regulator
MA06_RS25840	COG1174	glycine betaine transport
MA06_RS25870	COG1151	hydroxylamine reductase activity
MA06_RS25880	COG1253	flavin adenine dinucleotide binding
MA06_RS25885	COG5506	Protein of unknown function (DUF1694)
MA06_RS25905	COG3842	ATPase activity
MA06_RS25910	COG2508	Transcriptional regulator
MA06_RS25915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MA06_RS25920	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MA06_RS25925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MA06_RS25930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MA06_RS25935	COG0456	acetyltransferase
MA06_RS25940	COG3829	transcription factor binding
MA06_RS25945	COG1509	lysine 2,3-aminomutase activity
MA06_RS25970	COG4991	sh3 domain protein
MA06_RS25970	COG3064	Membrane
MA06_RS25970	COG0515	serine threonine protein kinase
MA06_RS25975	COG4326	sporulation control protein
MA06_RS25980	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS25985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MA06_RS25990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MA06_RS26010	COG5632	N-Acetylmuramoyl-L-alanine amidase
MA06_RS26060	COG0756	dUTP diphosphatase activity
MA06_RS26090	COG0488	(ABC) transporter
MA06_RS26105	COG0457	Tetratricopeptide repeat
MA06_RS26120	COG0494	nUDIX hydrolase
MA06_RS26180	COG2814	Major facilitator Superfamily
MA06_RS26215	COG0586	Pfam SNARE associated Golgi protein
MA06_RS26240	COG0823	Involved in the tonB-independent uptake of proteins
MA06_RS26240	COG1506	peptidase
MA06_RS26260	COG4499	WXG100 protein secretion system (Wss), protein YukC
MA06_RS26260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MA06_RS26280	COG2079	MmgE PrpD family protein
MA06_RS26285	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MA06_RS26290	COG3290	protein histidine kinase activity
MA06_RS26290	COG3829	transcription factor binding
MA06_RS26295	COG1960	acyl-CoA dehydrogenase activity
MA06_RS26300	COG2084	Dehydrogenase
MA06_RS26310	COG1280	lysine exporter protein (LysE YggA)
MA06_RS26320	COG1024	Enoyl-CoA hydratase
MA06_RS26335	COG0420	3'-5' exonuclease activity
MA06_RS26340	COG0419	ATPase involved in DNA repair
MA06_RS26345	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS26350	COG1169	isochorismate synthase
MA06_RS26355	COG1021	2,3-dihydroxybenzoate-AMP ligase
MA06_RS26360	COG1535	isochorismatase
MA06_RS26360	COG3433	isochorismatase activity
MA06_RS26365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MA06_RS26370	COG3251	PFAM MbtH domain protein
MA06_RS26375	COG0477	Major facilitator Superfamily
MA06_RS26390	COG0776	regulation of translation
MA06_RS26400	COG2318	DinB family
MA06_RS26410	COG1115	amino acid carrier protein
MA06_RS26430	COG2329	Antibiotic biosynthesis monooxygenase
MA06_RS26435	COG1187	pseudouridine synthase activity
MA06_RS26440	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MA06_RS26445	COG1136	(ABC) transporter
MA06_RS26495	COG4372	Transposase
MA06_RS26545	COG3331	DNA recombination
MA06_RS26595	COG2186	Transcriptional regulator
MA06_RS26625	COG0028	Belongs to the TPP enzyme family
MA06_RS26645	COG0588	phosphoglycerate mutase activity
MA06_RS26650	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS26655	COG0588	phosphoglycerate mutase activity
MA06_RS26660	COG1247	-acetyltransferase
MA06_RS26670	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MA06_RS26680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS26705	COG1846	Transcriptional regulator
MA06_RS26710	COG0477	Major facilitator Superfamily
MA06_RS26715	COG0583	DNA-binding transcription factor activity
MA06_RS26720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MA06_RS26725	COG2258	MOSC domain
MA06_RS26730	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
MA06_RS26735	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MA06_RS26740	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MA06_RS26750	COG1132	(ABC) transporter
MA06_RS26755	COG1132	(ABC) transporter
MA06_RS26770	COG1247	-acetyltransferase
MA06_RS26800	COG0318	PFAM AMP-dependent synthetase and ligase
MA06_RS26815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MA06_RS26830	COG1649	PFAM Uncharacterised BCR, COG1649
MA06_RS26850	COG2971	BadF BadG BcrA BcrD
MA06_RS26890	COG1309	transcriptional regulator
MA06_RS26935	COG2195	Cleaves the N-terminal amino acid of tripeptides
MA06_RS26940	COG1408	metallophosphoesterase
MA06_RS26950	COG1131	(ABC) transporter
MA06_RS26960	COG1309	transcriptional regulator
MA06_RS26990	COG1131	(ABC) transporter
MA06_RS27000	COG1725	Transcriptional regulator
MA06_RS27025	COG1960	acyl-CoA dehydrogenase activity
MA06_RS27030	COG0439	Biotin carboxylase
MA06_RS27035	COG0511	ligase activity, forming carbon-carbon bonds
MA06_RS27040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MA06_RS27045	COG1024	Enoyl-CoA hydratase
MA06_RS27050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MA06_RS27055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MA06_RS27060	COG0640	Transcriptional regulator
MA06_RS27065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MA06_RS27075	COG2318	DinB family
MA06_RS27090	COG1686	Belongs to the peptidase S11 family
MA06_RS27095	COG5002	protein histidine kinase activity
MA06_RS27105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MA06_RS27140	COG0697	spore germination
MA06_RS27145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS27175	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS27180	COG2323	membrane
MA06_RS27185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MA06_RS27195	COG0201	protein transport
MA06_RS27200	COG2162	N-hydroxyarylamine O-acetyltransferase activity
MA06_RS27210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MA06_RS27220	COG0322	excinuclease ABC activity
MA06_RS27235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MA06_RS27245	COG2318	DinB family
MA06_RS27260	COG4667	esterase of the alpha-beta hydrolase superfamily
MA06_RS27290	COG0561	phosphatase activity
MA06_RS27305	COG0494	nUDIX hydrolase
MA06_RS27315	COG2223	nitrite transmembrane transporter activity
MA06_RS27325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MA06_RS27345	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MA06_RS27360	COG0584	glycerophosphoryl diester phosphodiesterase
MA06_RS27365	COG2814	Major facilitator Superfamily
MA06_RS27380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS27395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MA06_RS27405	COG0671	phosphoesterase, PA-phosphatase related
MA06_RS27410	COG5002	protein histidine kinase activity
MA06_RS27415	COG0745	RESPONSE REGULATOR receiver
MA06_RS27435	COG2205	protein histidine kinase activity
MA06_RS27465	COG1794	racemase activity, acting on amino acids and derivatives
MA06_RS27470	COG5002	protein histidine kinase activity
MA06_RS27475	COG0561	phosphatase activity
MA06_RS27500	COG2814	Major facilitator Superfamily
MA06_RS27505	COG2124	cytochrome p450
MA06_RS27535	COG3173	Aminoglycoside phosphotransferase
MA06_RS27540	COG1073	alpha beta
MA06_RS27545	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MA06_RS27555	COG0460	homoserine dehydrogenase
MA06_RS27570	COG0577	efflux transmembrane transporter activity
MA06_RS27575	COG1136	(ABC) transporter
MA06_RS27580	COG2205	protein histidine kinase activity
MA06_RS27585	COG0745	RESPONSE REGULATOR receiver
MA06_RS27595	COG4585	Histidine kinase
MA06_RS27600	COG2197	response regulator
MA06_RS27605	COG2226	methyltransferase
MA06_RS27610	COG3773	Cell wall hydrolase
MA06_RS27620	COG3386	PFAM SMP-30 Gluconolaconase
MA06_RS27640	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS27650	COG2959	enzyme of heme biosynthesis
MA06_RS27690	COG1309	transcriptional regulator
MA06_RS27710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MA06_RS27715	COG0022	dehydrogenase e1 component
MA06_RS27720	COG1028	Short-chain dehydrogenase reductase Sdr
MA06_RS27750	COG4176	ABC-type proline glycine betaine transport system permease component
MA06_RS27755	COG4175	Glycine betaine
MA06_RS27755	COG0517	IMP dehydrogenase activity
MA06_RS27780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MA06_RS27790	COG2153	protein acetylation
MA06_RS27800	COG2205	protein histidine kinase activity
MA06_RS27835	COG0500	methyltransferase
MA06_RS27835	COG3615	Tellurite resistance protein tehB
MA06_RS27930	COG0457	Tetratricopeptide repeat
MA06_RS27935	COG3227	Zinc metalloprotease (Elastase)
MA06_RS27940	COG3973	AAA domain
MA06_RS27945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MA06_RS27960	COG0514	ATP-dependent DNA helicase (RecQ)
MA06_RS27965	COG0583	DNA-binding transcription factor activity
MA06_RS27980	COG4637	Psort location Cytoplasmic, score
MA06_RS27985	COG1227	inorganic diphosphatase activity
MA06_RS27990	COG2267	carboxylic ester hydrolase activity
MA06_RS28000	COG1115	amino acid carrier protein
MA06_RS28005	COG1012	belongs to the aldehyde dehydrogenase family
MA06_RS28010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MA06_RS28020	COG3938	Belongs to the proline racemase family
MA06_RS28025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MA06_RS28070	COG1078	dGTPase activity
MA06_RS28075	COG0586	Pfam SNARE associated Golgi protein
MA06_RS28085	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MA06_RS28095	COG4166	transmembrane transport
MA06_RS28105	COG4948	Mandelate Racemase Muconate Lactonizing
MA06_RS28125	COG0667	Aldo Keto reductase
MA06_RS28140	COG2936	dipeptidyl-peptidase activity
MA06_RS28150	COG3773	Cell wall hydrolase
MA06_RS28155	COG2205	protein histidine kinase activity
MA06_RS28160	COG0745	RESPONSE REGULATOR receiver
MA06_RS28175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MA06_RS28180	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
MA06_RS28185	COG1164	Oligoendopeptidase f
MA06_RS28195	COG0583	DNA-binding transcription factor activity
MA06_RS28200	COG0667	Aldo Keto reductase
MA06_RS28210	COG2356	endonuclease I
MA06_RS28225	COG1307	EDD domain protein, DegV family
MA06_RS28245	COG2814	Major facilitator Superfamily
MA06_RS28255	COG1664	Polymer-forming cytoskeletal
MA06_RS28260	COG0789	Transcriptional regulator
MA06_RS28265	COG4533	DNA binding
MA06_RS28270	COG0477	Major facilitator Superfamily
MA06_RS28270	COG2814	Major facilitator Superfamily
MA06_RS28285	COG2261	transglycosylase associated protein
MA06_RS28305	COG1131	(ABC) transporter
MA06_RS28325	COG2226	methyltransferase
MA06_RS28340	COG4869	propanediol catabolic process
MA06_RS28345	COG0436	Aminotransferase
MA06_RS28350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MA06_RS28365	COG3973	AAA domain
MA06_RS28370	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MA06_RS28465	COG2801	Transposase and inactivated derivatives
MA06_RS28535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MA06_RS28615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MA06_RS28760	COG0673	inositol 2-dehydrogenase activity
MA06_RS28895	COG0183	Belongs to the thiolase family
MA06_RS28900	COG0183	Belongs to the thiolase family
MA06_RS29025	COG2814	Major facilitator Superfamily
MA06_RS29060	COG3093	addiction module antidote protein HigA
MA06_RS29255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MA06_RS29550	COG2376	Dihydroxyacetone kinase
MA06_RS29630	COG0438	transferase activity, transferring glycosyl groups
MA06_RS29630	COG1216	Glycosyl transferase, family 2
MA06_RS29670	COG1388	LysM domain
MA06_RS29670	COG3584	3D domain protein
MA06_RS29785	COG1280	lysine exporter protein (LysE YggA)
MA06_RS29895	COG5632	N-Acetylmuramoyl-L-alanine amidase