locus-tag	class	description
LG401_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LG401_RS00010	COG0592	DNA-directed DNA polymerase activity
LG401_RS00015	COG2501	S4 domain
LG401_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LG401_RS00030	COG0187	DNA topoisomerase II activity
LG401_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LG401_RS00070	COG0516	GMP reductase activity
LG401_RS00070	COG0517	IMP dehydrogenase activity
LG401_RS00075	COG1686	Belongs to the peptidase S11 family
LG401_RS00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG401_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LG401_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LG401_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LG401_RS00110	COG1428	Deoxynucleoside kinase
LG401_RS00115	COG1428	Deoxynucleoside kinase
LG401_RS00120	COG3858	chitin binding
LG401_RS00120	COG1388	LysM domain
LG401_RS00125	COG1335	isochorismatase
LG401_RS00130	COG0590	tRNA wobble adenosine to inosine editing
LG401_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LG401_RS00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LG401_RS00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LG401_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
LG401_RS00200	COG3853	Toxic anion resistance protein (TelA)
LG401_RS00205	COG1982	Orn Lys Arg decarboxylase major
LG401_RS00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LG401_RS00215	COG3870	Protein conserved in bacteria
LG401_RS00220	COG1728	Protein conserved in bacteria
LG401_RS00225	COG0470	DNA polymerase III
LG401_RS00235	COG4467	Involved in initiation control of chromosome replication
LG401_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LG401_RS00245	COG2827	Endonuclease containing a URI domain
LG401_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LG401_RS00255	COG2002	toxin-antitoxin pair type II binding
LG401_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG401_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG401_RS00265	COG0084	hydrolase, TatD family'
LG401_RS00270	COG3583	domain protein
LG401_RS00270	COG3584	3D domain protein
LG401_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LG401_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LG401_RS00290	COG4466	Protein conserved in bacteria
LG401_RS00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LG401_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG401_RS00310	COG0251	oxidation-reduction process
LG401_RS00315	COG2088	sporulation resulting in formation of a cellular spore
LG401_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LG401_RS00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LG401_RS00335	COG0193	aminoacyl-tRNA hydrolase activity
LG401_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LG401_RS00350	COG2002	toxin-antitoxin pair type II binding
LG401_RS00355	COG2244	polysaccharide biosynthetic process
LG401_RS00360	COG3956	TIGRFAM MazG family protein
LG401_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LG401_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LG401_RS00385	COG1098	S1 RNA binding domain
LG401_RS00400	COG2208	phosphoserine phosphatase activity
LG401_RS00405	COG2304	oxidoreductase activity
LG401_RS00410	COG0515	serine threonine protein kinase
LG401_RS00415	COG0037	tRNA processing
LG401_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LG401_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LG401_RS00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LG401_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LG401_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG401_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG401_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LG401_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
LG401_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG401_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LG401_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LG401_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LG401_RS00480	COG1396	sequence-specific DNA binding
LG401_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG401_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LG401_RS00570	COG4463	regulation of RNA biosynthetic process
LG401_RS00575	COG3880	PFAM UvrB UvrC protein
LG401_RS00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LG401_RS00585	COG0542	response to heat
LG401_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LG401_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LG401_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
LG401_RS00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LG401_RS00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LG401_RS00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LG401_RS00620	COG1045	serine acetyltransferase
LG401_RS00625	COG0215	cysteine-tRNA ligase activity
LG401_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LG401_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG401_RS00640	COG3688	RNA-binding protein containing a PIN domain
LG401_RS00645	COG1595	DNA-templated transcription, initiation
LG401_RS00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG401_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LG401_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
LG401_RS00670	COG0081	regulation of translation
LG401_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LG401_RS00680	COG0222	ribosome binding
LG401_RS00685	COG2813	Specifically methylates the guanine in position
LG401_RS00690	COG0085	RNA polymerase activity
LG401_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LG401_RS00700	COG1358	cellular component organization or biogenesis
LG401_RS00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LG401_RS00710	COG0049	tRNA binding
LG401_RS00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LG401_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LG401_RS00725	COG0596	Alpha beta hydrolase
LG401_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LG401_RS00740	COG0088	Forms part of the polypeptide exit tunnel
LG401_RS00745	COG0089	rRNA binding
LG401_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LG401_RS00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LG401_RS00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LG401_RS00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LG401_RS00775	COG0255	Belongs to the universal ribosomal protein uL29 family
LG401_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LG401_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LG401_RS00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LG401_RS00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LG401_RS00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LG401_RS00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LG401_RS00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LG401_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LG401_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LG401_RS00825	COG1841	ribosomal large subunit assembly
LG401_RS00830	COG0200	Binds to the 23S rRNA
LG401_RS00835	COG0201	protein transport
LG401_RS00840	COG0563	adenylate kinase activity
LG401_RS00845	COG0024	Methionine aminopeptidase
LG401_RS00855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LG401_RS00860	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LG401_RS00865	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LG401_RS00870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LG401_RS00875	COG0202	RNA polymerase activity
LG401_RS00880	COG0203	ribosomal protein L17
LG401_RS00885	COG1122	ATPase activity
LG401_RS00890	COG1122	ATPase activity
LG401_RS00895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG401_RS00900	COG0101	tRNA pseudouridine synthase activity
LG401_RS00905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LG401_RS00910	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LG401_RS00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG401_RS00945	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG401_RS00950	COG0489	protein tyrosine kinase activity
LG401_RS00960	COG2194	sulfuric ester hydrolase activity
LG401_RS00965	COG0726	polysaccharide deacetylase
LG401_RS00995	COG0659	secondary active sulfate transmembrane transporter activity
LG401_RS01000	COG0385	Bile acid
LG401_RS01005	COG3876	Protein conserved in bacteria
LG401_RS01015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG401_RS01020	COG1263	PTS System
LG401_RS01020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS01025	COG1737	Transcriptional regulator
LG401_RS01030	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LG401_RS01065	COG1595	DNA-templated transcription, initiation
LG401_RS01070	COG5662	AntiSigma factor
LG401_RS01075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LG401_RS01080	COG4856	YbbR-like protein
LG401_RS01085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG401_RS01090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LG401_RS01110	COG1131	(ABC) transporter
LG401_RS01125	COG1131	(ABC) transporter
LG401_RS01135	COG1413	lyase activity
LG401_RS01145	COG2311	Membrane
LG401_RS01170	COG1309	transcriptional regulator
LG401_RS01185	COG1113	amino acid transport
LG401_RS01190	COG0584	glycerophosphoryl diester phosphodiesterase
LG401_RS01195	COG2271	Major facilitator Superfamily
LG401_RS01205	COG1331	Highly conserved protein containing a thioredoxin domain
LG401_RS01215	COG1404	Belongs to the peptidase S8 family
LG401_RS01240	COG1131	(ABC) transporter
LG401_RS01270	COG1937	Protein conserved in bacteria
LG401_RS01275	COG2210	Belongs to the sulfur carrier protein TusA family
LG401_RS01280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG401_RS01285	COG0425	Belongs to the sulfur carrier protein TusA family
LG401_RS01285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG401_RS01290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS01290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG401_RS01295	COG0425	Belongs to the sulfur carrier protein TusA family
LG401_RS01300	COG0730	response to heat
LG401_RS01310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG401_RS01315	COG2814	Major facilitator Superfamily
LG401_RS01320	COG1846	Transcriptional regulator
LG401_RS01330	COG1683	Conserved Protein
LG401_RS01340	COG0656	L-ascorbic acid biosynthetic process
LG401_RS01345	COG0371	Dehydrogenase
LG401_RS01350	COG1054	Belongs to the UPF0176 family
LG401_RS01355	COG0531	amino acid
LG401_RS01365	COG3711	transcriptional antiterminator
LG401_RS01370	COG2190	(PTS) system
LG401_RS01370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS01370	COG1263	PTS System
LG401_RS01375	COG2723	6-phospho-beta-galactosidase activity
LG401_RS01385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS01385	COG3711	transcriptional antiterminator
LG401_RS01390	COG1940	carbohydrate kinase activity
LG401_RS01395	COG0383	alpha-mannosidase activity
LG401_RS01400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS01405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS01415	COG1404	Belongs to the peptidase S8 family
LG401_RS01430	COG0833	amino acid
LG401_RS01435	COG2040	homocysteine
LG401_RS01440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG401_RS01445	COG1695	Transcriptional regulator
LG401_RS01460	COG2814	Major facilitator Superfamily
LG401_RS01465	COG0456	acetyltransferase
LG401_RS01480	COG1404	Belongs to the peptidase S8 family
LG401_RS01490	COG1309	transcriptional regulator
LG401_RS01495	COG1917	Cupin 2, conserved barrel domain protein
LG401_RS01500	COG1063	alcohol dehydrogenase
LG401_RS01505	COG1846	Transcriptional regulator
LG401_RS01510	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS01515	COG0531	amino acid
LG401_RS01535	COG0596	Alpha beta hydrolase
LG401_RS01540	COG1115	amino acid carrier protein
LG401_RS01545	COG2066	Belongs to the glutaminase family
LG401_RS01550	COG4191	Histidine kinase
LG401_RS01555	COG0784	Response regulator, receiver
LG401_RS01560	COG3012	SEC-C Motif Domain Protein
LG401_RS01560	COG1405	negative regulation of cell septum assembly
LG401_RS01570	COG0667	Aldo Keto reductase
LG401_RS01575	COG3290	protein histidine kinase activity
LG401_RS01580	COG3279	Response regulator of the LytR AlgR family
LG401_RS01585	COG4555	ABC transporter
LG401_RS01590	COG1668	transmembrane transport
LG401_RS01605	COG3773	Cell wall hydrolase
LG401_RS01610	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS01620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG401_RS01625	COG2310	stress, protein
LG401_RS01630	COG2310	stress, protein
LG401_RS01635	COG2310	stress, protein
LG401_RS01640	COG0861	Integral membrane protein TerC family
LG401_RS01670	COG3853	Toxic anion resistance protein (TelA)
LG401_RS01675	COG4175	Glycine betaine
LG401_RS01675	COG0517	IMP dehydrogenase activity
LG401_RS01680	COG4176	ABC-type proline glycine betaine transport system permease component
LG401_RS01685	COG2113	Glycine betaine
LG401_RS01700	COG1473	amidohydrolase
LG401_RS01705	COG1288	antiporter activity
LG401_RS01710	COG0039	L-malate dehydrogenase activity
LG401_RS01715	COG1620	l-lactate permease
LG401_RS01720	COG1609	Transcriptional regulator
LG401_RS01725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG401_RS01730	COG0561	phosphatase activity
LG401_RS01735	COG0673	inositol 2-dehydrogenase activity
LG401_RS01740	COG0738	Major facilitator superfamily
LG401_RS01745	COG1280	lysine exporter protein (LysE YggA)
LG401_RS01755	COG3403	YqcI/YcgG family
LG401_RS01760	COG1113	amino acid transport
LG401_RS01765	COG3665	Urea carboxylase-associated protein
LG401_RS01770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LG401_RS01775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LG401_RS01785	COG0477	Major facilitator Superfamily
LG401_RS01790	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LG401_RS01795	COG2226	methyltransferase
LG401_RS01800	COG0583	DNA-binding transcription factor activity
LG401_RS01805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG401_RS01810	COG3458	cephalosporin-C deacetylase activity
LG401_RS01820	COG3541	Predicted nucleotidyltransferase
LG401_RS01825	COG0506	proline dehydrogenase activity
LG401_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS01835	COG2508	Transcriptional regulator
LG401_RS01840	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LG401_RS01845	COG0765	amino acid transport
LG401_RS01850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS01860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LG401_RS01865	COG1522	sequence-specific DNA binding
LG401_RS01870	COG2746	aminoglycoside 3-N-acetyltransferase activity
LG401_RS01880	COG0840	transmembrane signaling receptor activity
LG401_RS01880	COG3290	protein histidine kinase activity
LG401_RS01885	COG3209	COG3209 Rhs family protein
LG401_RS01905	COG3842	ATPase activity
LG401_RS01910	COG1176	ABC-type spermidine putrescine transport system, permease component I
LG401_RS01920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG401_RS01925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG401_RS01930	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG401_RS01945	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LG401_RS01960	COG4555	ABC transporter
LG401_RS01975	COG0697	spore germination
LG401_RS01980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG401_RS01990	COG2364	Membrane
LG401_RS01995	COG1126	abc transporter atp-binding protein
LG401_RS02000	COG0765	amino acid transport
LG401_RS02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS02010	COG0833	amino acid
LG401_RS02015	COG3104	oligopeptide transport
LG401_RS02020	COG5434	Belongs to the glycosyl hydrolase 28 family
LG401_RS02025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG401_RS02030	COG0456	acetyltransferase
LG401_RS02035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS02040	COG0765	amino acid transport
LG401_RS02045	COG1126	abc transporter atp-binding protein
LG401_RS02050	COG1473	amidohydrolase
LG401_RS02055	COG2079	MmgE PrpD family protein
LG401_RS02060	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS02065	COG0527	aspartate kinase activity
LG401_RS02070	COG2814	Major facilitator Superfamily
LG401_RS02075	COG1309	transcriptional regulator
LG401_RS02085	COG0640	Transcriptional regulator
LG401_RS02090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG401_RS02095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LG401_RS02100	COG0531	amino acid
LG401_RS02105	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS02110	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG401_RS02115	COG4549	nuclear export factor GLE1
LG401_RS02120	COG2372	response to copper ion
LG401_RS02120	COG1276	copper resistance
LG401_RS02125	COG2213	PTS system mannitol-specific
LG401_RS02130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS02135	COG0246	Mannitol dehydrogenase
LG401_RS02140	COG0840	transmembrane signaling receptor activity
LG401_RS02160	COG0346	lactoylglutathione lyase activity
LG401_RS02170	COG0561	phosphatase activity
LG401_RS02175	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LG401_RS02180	COG1914	H( )-stimulated, divalent metal cation uptake system
LG401_RS02185	COG4336	lyase activity
LG401_RS02190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LG401_RS02195	COG1984	allophanate hydrolase subunit 2
LG401_RS02200	COG1414	Transcriptional regulator
LG401_RS02205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG401_RS02210	COG2755	lipolytic protein G-D-S-L family
LG401_RS02220	COG3711	transcriptional antiterminator
LG401_RS02225	COG2226	methyltransferase
LG401_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS02235	COG3871	stress protein (general stress protein 26)
LG401_RS02255	COG2814	Major facilitator Superfamily
LG401_RS02260	COG1802	Transcriptional regulator
LG401_RS02265	COG2207	Transcriptional regulator
LG401_RS02265	COG1917	Cupin 2, conserved barrel domain protein
LG401_RS02270	COG0697	spore germination
LG401_RS02275	COG0473	3-isopropylmalate dehydrogenase activity
LG401_RS02280	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LG401_RS02280	COG0551	DNA topoisomerase type I activity
LG401_RS02285	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LG401_RS02290	COG3706	GGDEF domain
LG401_RS02295	COG5298	Protein conserved in bacteria
LG401_RS02300	COG1215	transferase activity, transferring glycosyl groups
LG401_RS02310	COG0531	amino acid
LG401_RS02315	COG0028	Belongs to the TPP enzyme family
LG401_RS02320	COG5444	nuclease activity
LG401_RS02345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG401_RS02350	COG1914	H( )-stimulated, divalent metal cation uptake system
LG401_RS02355	COG2261	transglycosylase associated protein
LG401_RS02360	COG2217	Heavy metal translocating P-type atpase
LG401_RS02365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LG401_RS02370	COG3290	protein histidine kinase activity
LG401_RS02375	COG4565	transcriptional regulatory protein
LG401_RS02380	COG1301	dicarboxylic acid transport
LG401_RS02385	COG0628	permease
LG401_RS02390	COG1301	dicarboxylic acid transport
LG401_RS02395	COG1131	(ABC) transporter
LG401_RS02400	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LG401_RS02415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS02420	COG1181	Belongs to the D-alanine--D-alanine ligase family
LG401_RS02425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LG401_RS02440	COG0513	Belongs to the DEAD box helicase family
LG401_RS02445	COG3402	PFAM membrane-flanked domain
LG401_RS02450	COG3428	Bacterial PH domain
LG401_RS02455	COG0705	Rhomboid family
LG401_RS02460	COG0736	holo-[acyl-carrier-protein] synthase activity
LG401_RS02465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LG401_RS02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LG401_RS02475	COG0864	Transcriptional regulator
LG401_RS02480	COG2337	Toxic component of a toxin-antitoxin (TA) module
LG401_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS02495	COG2172	sigma factor antagonist activity
LG401_RS02500	COG2208	phosphoserine phosphatase activity
LG401_RS02505	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS02510	COG2172	sigma factor antagonist activity
LG401_RS02515	COG1191	sigma factor activity
LG401_RS02520	COG2208	phosphoserine phosphatase activity
LG401_RS02525	COG2183	response to ionizing radiation
LG401_RS02535	COG3091	SprT-like family
LG401_RS02540	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG401_RS02545	COG0022	dehydrogenase e1 component
LG401_RS02550	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS02560	COG3284	Transcriptional regulator
LG401_RS02600	COG0604	alcohol dehydrogenase
LG401_RS02615	COG0456	acetyltransferase
LG401_RS02615	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG401_RS02620	COG1278	Cold shock
LG401_RS02625	COG1329	Transcriptional regulator
LG401_RS02630	COG1064	alcohol dehydrogenase
LG401_RS02635	COG0789	Transcriptional regulator
LG401_RS02650	COG0477	Major facilitator Superfamily
LG401_RS02655	COG0657	acetylesterase activity
LG401_RS02685	COG0252	asparaginase activity
LG401_RS02705	COG2814	Major facilitator Superfamily
LG401_RS02740	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LG401_RS02745	COG1846	Transcriptional regulator
LG401_RS02750	COG0778	Nitroreductase
LG401_RS02765	COG1396	sequence-specific DNA binding
LG401_RS02775	COG0456	acetyltransferase
LG401_RS02780	COG0583	DNA-binding transcription factor activity
LG401_RS02785	COG0667	Aldo Keto reductase
LG401_RS02795	COG4122	O-methyltransferase activity
LG401_RS02805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LG401_RS02810	COG0697	spore germination
LG401_RS02820	COG1301	dicarboxylic acid transport
LG401_RS02860	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LG401_RS02865	COG0802	atpase or kinase
LG401_RS02870	COG1214	PFAM Peptidase M22, glycoprotease
LG401_RS02875	COG0456	acetyltransferase
LG401_RS02880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LG401_RS02885	COG0488	(ABC) transporter
LG401_RS02890	COG0315	cyclic pyranopterin monophosphate synthase activity
LG401_RS02895	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LG401_RS02900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LG401_RS02905	COG0805	protein transport
LG401_RS02910	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LG401_RS02920	COG1266	CAAX protease self-immunity
LG401_RS02925	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LG401_RS02930	COG0459	protein refolding
LG401_RS02940	COG1846	Transcriptional regulator
LG401_RS02945	COG0456	acetyltransferase
LG401_RS02950	COG2808	Putative FMN-binding domain
LG401_RS02980	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LG401_RS02985	COG0823	Involved in the tonB-independent uptake of proteins
LG401_RS03000	COG2132	Multicopper oxidase
LG401_RS03005	COG1113	amino acid transport
LG401_RS03010	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LG401_RS03015	COG0714	Associated with various cellular activities
LG401_RS03020	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LG401_RS03025	COG1305	Transglutaminase-like
LG401_RS03030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LG401_RS03030	COG0519	Catalyzes the synthesis of GMP from XMP
LG401_RS03040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LG401_RS03045	COG1917	Cupin 2, conserved barrel domain protein
LG401_RS03045	COG2207	Transcriptional regulator
LG401_RS03050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG401_RS03055	COG2207	Transcriptional regulator
LG401_RS03065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG401_RS03075	COG0662	Cupin 2, conserved barrel domain protein
LG401_RS03080	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LG401_RS03120	COG2814	Major facilitator Superfamily
LG401_RS03125	COG0583	DNA-binding transcription factor activity
LG401_RS03130	COG2252	PERMEase
LG401_RS03135	COG3064	Membrane
LG401_RS03140	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LG401_RS03150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LG401_RS03155	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LG401_RS03160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LG401_RS03165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LG401_RS03170	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG401_RS03175	COG0047	phosphoribosylformylglycinamidine synthase activity
LG401_RS03180	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LG401_RS03185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LG401_RS03190	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LG401_RS03195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LG401_RS03200	COG0138	bifunctional purine biosynthesis protein purh
LG401_RS03205	COG0151	Belongs to the GarS family
LG401_RS03225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LG401_RS03230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LG401_RS03235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LG401_RS03240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG401_RS03250	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG401_RS03255	COG4496	protein, YerC YecD
LG401_RS03260	COG0069	glutamate synthase activity
LG401_RS03275	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LG401_RS03280	COG0210	DNA helicase
LG401_RS03285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LG401_RS03290	COG4851	CamS sex pheromone cAM373 precursor
LG401_RS03305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LG401_RS03320	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG401_RS03335	COG1960	acyl-CoA dehydrogenase activity
LG401_RS03365	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG401_RS03370	COG1785	Belongs to the alkaline phosphatase family
LG401_RS03375	COG1285	pathogenesis
LG401_RS03380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG401_RS03385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG401_RS03390	COG0154	amidase activity
LG401_RS03395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LG401_RS03400	COG1309	transcriptional regulator
LG401_RS03405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG401_RS03410	COG1957	nucleoside hydrolase
LG401_RS03415	COG1597	lipid kinase activity
LG401_RS03420	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LG401_RS03430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LG401_RS03440	COG1737	Transcriptional regulator
LG401_RS03445	COG1263	PTS System
LG401_RS03445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS03465	COG0492	ferredoxin-NADP+ reductase activity
LG401_RS03480	COG1486	melibiose metabolic process
LG401_RS03490	COG2211	Major facilitator Superfamily
LG401_RS03520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LG401_RS03525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG401_RS03530	COG1442	glycosyl transferase family 8
LG401_RS03535	COG1216	Glycosyl transferase, family 2
LG401_RS03540	COG1442	glycosyl transferase family 8
LG401_RS03545	COG2223	nitrite transmembrane transporter activity
LG401_RS03555	COG0471	metal ion transport
LG401_RS03560	COG0531	amino acid
LG401_RS03565	COG0463	Glycosyl transferase, family 2
LG401_RS03565	COG0457	Tetratricopeptide repeat
LG401_RS03570	COG0488	(ABC) transporter
LG401_RS03575	COG1469	GTP cyclohydrolase I activity
LG401_RS03580	COG0789	Transcriptional regulator
LG401_RS03585	COG2814	Major facilitator Superfamily
LG401_RS03590	COG0488	(ABC) transporter
LG401_RS03595	COG0513	Belongs to the DEAD box helicase family
LG401_RS03600	COG2130	NADP-dependent
LG401_RS03620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG401_RS03620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG401_RS03625	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LG401_RS03635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG401_RS03635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG401_RS03645	COG3290	protein histidine kinase activity
LG401_RS03650	COG4565	transcriptional regulatory protein
LG401_RS03655	COG3181	Tripartite tricarboxylate transporter family receptor
LG401_RS03660	COG2851	Citrate transporter
LG401_RS03670	COG3479	Phenolic acid decarboxylase
LG401_RS03675	COG1695	Transcriptional regulator
LG401_RS03680	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LG401_RS03685	COG1254	Belongs to the acylphosphatase family
LG401_RS03690	COG2258	MOSC domain
LG401_RS03705	COG0024	Methionine aminopeptidase
LG401_RS03710	COG1263	PTS System
LG401_RS03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS03715	COG3739	integral membrane protein
LG401_RS03730	COG1368	sulfuric ester hydrolase activity
LG401_RS03735	COG0076	glutamate decarboxylase activity
LG401_RS03740	COG0840	transmembrane signaling receptor activity
LG401_RS03750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS03750	COG1263	PTS System
LG401_RS03755	COG0366	Alpha amylase catalytic
LG401_RS03760	COG2188	Transcriptional regulator
LG401_RS03770	COG0737	Belongs to the 5'-nucleotidase family
LG401_RS03775	COG0693	protein deglycase activity
LG401_RS03780	COG4840	Belongs to the UPF0435 family
LG401_RS03785	COG1115	amino acid carrier protein
LG401_RS03790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG401_RS03795	COG4980	gas vesicle protein
LG401_RS03800	COG1295	ribonuclease BN
LG401_RS03805	COG0477	Major facilitator Superfamily
LG401_RS03815	COG0387	Pfam Sodium calcium exchanger
LG401_RS03830	COG4152	abc transporter atp-binding protein
LG401_RS03850	COG0217	transcriptional regulatory protein
LG401_RS03860	COG0668	transmembrane transport
LG401_RS03865	COG0535	radical SAM domain protein
LG401_RS03875	COG0726	polysaccharide deacetylase
LG401_RS03885	COG0598	Magnesium transport protein CorA
LG401_RS03895	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LG401_RS03900	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LG401_RS03910	COG0789	Transcriptional regulator
LG401_RS03915	COG2814	Major facilitator Superfamily
LG401_RS03930	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG401_RS03970	COG2076	Multidrug Resistance protein
LG401_RS03975	COG2076	Multidrug Resistance protein
LG401_RS03980	COG1309	transcriptional regulator
LG401_RS03990	COG4637	Psort location Cytoplasmic, score
LG401_RS03995	COG2755	lipolytic protein G-D-S-L family
LG401_RS04000	COG0492	ferredoxin-NADP+ reductase activity
LG401_RS04020	COG2318	DinB family
LG401_RS04030	COG1846	Transcriptional regulator
LG401_RS04035	COG0392	lysyltransferase activity
LG401_RS04035	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LG401_RS04055	COG0778	Nitroreductase
LG401_RS04070	COG1090	epimerase
LG401_RS04075	COG2137	regulation of response to DNA damage stimulus
LG401_RS04100	COG0463	Glycosyl transferase, family 2
LG401_RS04105	COG4485	Bacterial membrane protein, YfhO
LG401_RS04120	COG2140	Oxalate decarboxylase
LG401_RS04130	COG1191	sigma factor activity
LG401_RS04175	COG1988	membrane-bound metal-dependent
LG401_RS04180	COG1194	a g-specific adenine glycosylase
LG401_RS04190	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS04205	COG3557	Belongs to the UPF0374 family
LG401_RS04210	COG1132	(ABC) transporter
LG401_RS04215	COG0444	Belongs to the ABC transporter superfamily
LG401_RS04220	COG4608	Belongs to the ABC transporter superfamily
LG401_RS04225	COG0747	negative chemotaxis
LG401_RS04230	COG0601	transmembrane transport
LG401_RS04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG401_RS04240	COG4129	membrane
LG401_RS04245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG401_RS04250	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LG401_RS04255	COG0735	belongs to the Fur family
LG401_RS04395	COG1368	sulfuric ester hydrolase activity
LG401_RS04400	COG0681	Belongs to the peptidase S26 family
LG401_RS04405	COG2873	o-acetylhomoserine
LG401_RS04415	COG1131	(ABC) transporter
LG401_RS04445	COG3382	B3 4 domain protein
LG401_RS04450	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LG401_RS04460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LG401_RS04470	COG2766	serine protein kinase
LG401_RS04475	COG2718	Belongs to the UPF0229 family
LG401_RS04480	COG1566	PFAM secretion protein HlyD family protein
LG401_RS04485	COG2814	Major facilitator Superfamily
LG401_RS04490	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG401_RS04500	COG1278	Cold shock
LG401_RS04505	COG3706	GGDEF domain
LG401_RS04530	COG5577	PFAM Coat F domain
LG401_RS04535	COG5002	protein histidine kinase activity
LG401_RS04540	COG0737	Belongs to the 5'-nucleotidase family
LG401_RS04540	COG4085	toxin activity
LG401_RS04540	COG1525	nuclease
LG401_RS04545	COG3764	Sortase (surface protein transpeptidase)
LG401_RS04550	COG0564	pseudouridine synthase activity
LG401_RS04560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LG401_RS04565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LG401_RS04565	COG3153	acetyltransferase
LG401_RS04580	COG3835	regulator
LG401_RS04585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LG401_RS04590	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LG401_RS04595	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LG401_RS04600	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LG401_RS04605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LG401_RS04610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LG401_RS04615	COG4585	Histidine kinase
LG401_RS04615	COG2203	Gaf domain
LG401_RS04620	COG2197	response regulator
LG401_RS04640	COG0753	catalase activity
LG401_RS04645	COG1959	2 iron, 2 sulfur cluster binding
LG401_RS04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LG401_RS04650	COG1017	nitric oxide dioxygenase activity
LG401_RS04655	COG2719	SpoVR family
LG401_RS04660	COG1785	Belongs to the alkaline phosphatase family
LG401_RS04665	COG0791	NLP P60 protein
LG401_RS04665	COG1388	LysM domain
LG401_RS04680	COG1595	DNA-templated transcription, initiation
LG401_RS04685	COG0204	Acyl-transferase
LG401_RS04690	COG1253	flavin adenine dinucleotide binding
LG401_RS04695	COG0789	Transcriptional regulator
LG401_RS04700	COG1253	flavin adenine dinucleotide binding
LG401_RS04715	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LG401_RS04720	COG0584	glycerophosphoryl diester phosphodiesterase
LG401_RS04730	COG0668	transmembrane transport
LG401_RS04735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LG401_RS04740	COG0726	polysaccharide deacetylase
LG401_RS04750	COG0589	response to stress
LG401_RS04755	COG1132	(ABC) transporter
LG401_RS04760	COG1132	(ABC) transporter
LG401_RS04765	COG0702	epimerase
LG401_RS04775	COG3842	ATPase activity
LG401_RS04780	COG2508	Transcriptional regulator
LG401_RS04790	COG0189	ligase activity
LG401_RS04795	COG0189	ligase activity
LG401_RS04800	COG4399	Belongs to the UPF0754 family
LG401_RS04805	COG3679	Belongs to the UPF0342 family
LG401_RS04810	COG0561	phosphatase activity
LG401_RS04815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG401_RS04825	COG0475	glutathione-regulated potassium exporter activity
LG401_RS04830	COG0490	domain, Protein
LG401_RS04835	COG1024	Enoyl-CoA hydratase
LG401_RS04845	COG0420	3'-5' exonuclease activity
LG401_RS04850	COG4717	serine-type aminopeptidase activity
LG401_RS04855	COG3481	metal-dependent phosphohydrolase, HD sub domain
LG401_RS04865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LG401_RS04895	COG1846	Transcriptional regulator
LG401_RS04900	COG4980	gas vesicle protein
LG401_RS04915	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LG401_RS04920	COG0537	adenosine 5'-monophosphoramidase activity
LG401_RS04925	COG1131	(ABC) transporter
LG401_RS04930	COG4473	ABC transporter
LG401_RS04940	COG1473	amidohydrolase
LG401_RS04950	COG2329	Antibiotic biosynthesis monooxygenase
LG401_RS04955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG401_RS04960	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LG401_RS04965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LG401_RS04970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LG401_RS04975	COG1309	transcriptional regulator
LG401_RS04980	COG1511	domain protein
LG401_RS04985	COG1363	Peptidase, m42
LG401_RS04990	COG1301	dicarboxylic acid transport
LG401_RS05000	COG1234	tRNA 3'-trailer cleavage
LG401_RS05005	COG0095	Lipoate-protein ligase
LG401_RS05010	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS05020	COG0501	Belongs to the peptidase M48B family
LG401_RS05025	COG1404	Belongs to the peptidase S8 family
LG401_RS05030	COG0406	alpha-ribazole phosphatase activity
LG401_RS05035	COG0840	transmembrane signaling receptor activity
LG401_RS05040	COG0723	plastoquinol--plastocyanin reductase activity
LG401_RS05040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LG401_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS05055	COG4903	ComK protein
LG401_RS05070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG401_RS05075	COG2814	Major facilitator Superfamily
LG401_RS05080	COG2732	(Barnase) inhibitor
LG401_RS05085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS05090	COG4605	iron ion homeostasis
LG401_RS05095	COG4604	ABC transporter, ATP-binding protein
LG401_RS05100	COG4607	ABC-type enterochelin transport system periplasmic component
LG401_RS05105	COG1316	TRANSCRIPTIONal
LG401_RS05115	COG0398	Pfam SNARE associated Golgi protein
LG401_RS05120	COG0681	Belongs to the peptidase S26 family
LG401_RS05125	COG3180	Ammonia monooxygenase
LG401_RS05140	COG2259	Doxx family
LG401_RS05145	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LG401_RS05150	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LG401_RS05155	COG1074	ATP-dependent DNA helicase activity
LG401_RS05160	COG0420	3'-5' exonuclease activity
LG401_RS05165	COG0419	ATPase involved in DNA repair
LG401_RS05170	COG1403	HNH endonuclease
LG401_RS05210	COG5337	Spore coat protein CotH
LG401_RS05220	COG0179	Fumarylacetoacetate (FAA) hydrolase
LG401_RS05235	COG0367	asparagine synthase
LG401_RS05250	COG1562	ergosterol biosynthetic process
LG401_RS05255	COG0534	Mate efflux family protein
LG401_RS05260	COG1917	Cupin 2, conserved barrel domain protein
LG401_RS05260	COG2207	Transcriptional regulator
LG401_RS05285	COG0076	glutamate decarboxylase activity
LG401_RS05315	COG0646	methionine synthase
LG401_RS05315	COG1410	methionine synthase
LG401_RS05320	COG0646	methionine synthase
LG401_RS05320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LG401_RS05325	COG1666	GTP binding
LG401_RS05330	COG2996	Protein conserved in bacteria
LG401_RS05335	COG1744	ABC transporter substrate-binding protein PnrA-like
LG401_RS05340	COG0840	transmembrane signaling receptor activity
LG401_RS05345	COG1307	EDD domain protein, DegV family
LG401_RS05350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG401_RS05370	COG0561	phosphatase activity
LG401_RS05375	COG1073	alpha beta
LG401_RS05380	COG2151	metal-sulfur cluster biosynthetic enzyme
LG401_RS05385	COG0277	FAD linked oxidase domain protein
LG401_RS05390	COG2271	Major facilitator Superfamily
LG401_RS05395	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LG401_RS05400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LG401_RS05405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LG401_RS05410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG401_RS05415	COG0505	Belongs to the CarA family
LG401_RS05420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG401_RS05425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LG401_RS05435	COG2814	Major facilitator Superfamily
LG401_RS05445	COG2267	carboxylic ester hydrolase activity
LG401_RS05455	COG1744	ABC transporter substrate-binding protein PnrA-like
LG401_RS05470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG401_RS05475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG401_RS05480	COG5504	Zn-dependent protease
LG401_RS05485	COG0444	Belongs to the ABC transporter superfamily
LG401_RS05490	COG4608	Belongs to the ABC transporter superfamily
LG401_RS05500	COG0601	transmembrane transport
LG401_RS05505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG401_RS05515	COG0180	Tryptophanyl-tRNA synthetase
LG401_RS05520	COG4166	transmembrane transport
LG401_RS05525	COG0601	transmembrane transport
LG401_RS05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG401_RS05535	COG0444	Belongs to the ABC transporter superfamily
LG401_RS05540	COG4608	Belongs to the ABC transporter superfamily
LG401_RS05550	COG0456	acetyltransferase
LG401_RS05555	COG1393	Belongs to the ArsC family
LG401_RS05560	COG0861	Integral membrane protein TerC family
LG401_RS05565	COG4862	establishment of competence for transformation
LG401_RS05570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG401_RS05580	COG1164	Oligoendopeptidase f
LG401_RS05590	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LG401_RS05595	COG2346	COG2346, Truncated hemoglobins
LG401_RS05600	COG0741	lytic transglycosylase activity
LG401_RS05605	COG4116	CYTH
LG401_RS05615	COG2357	RelA SpoT domain protein
LG401_RS05620	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG401_RS05625	COG0564	pseudouridine synthase activity
LG401_RS05630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LG401_RS05635	COG0569	domain protein
LG401_RS05635	COG0475	glutathione-regulated potassium exporter activity
LG401_RS05640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG401_RS05645	COG0352	thiamine-phosphate diphosphorylase activity
LG401_RS05655	COG2104	thiamine diphosphate biosynthetic process
LG401_RS05660	COG2022	thiamine diphosphate biosynthetic process
LG401_RS05665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LG401_RS05670	COG0351	phosphomethylpyrimidine kinase
LG401_RS05675	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LG401_RS05730	COG0210	DNA helicase
LG401_RS05740	COG2153	protein acetylation
LG401_RS05745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LG401_RS05750	COG2382	esterase
LG401_RS05755	COG0626	cystathionine gamma-synthase activity
LG401_RS05760	COG0626	cystathionine gamma-synthase activity
LG401_RS05770	COG0604	alcohol dehydrogenase
LG401_RS05785	COG0825	malonyl-CoA metabolic process
LG401_RS05800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG401_RS05830	COG0457	Tetratricopeptide repeat
LG401_RS05850	COG3173	Aminoglycoside phosphotransferase
LG401_RS05865	COG0583	DNA-binding transcription factor activity
LG401_RS05870	COG2807	transmembrane transport
LG401_RS05880	COG0457	Tetratricopeptide repeat
LG401_RS05895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LG401_RS05905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG401_RS05910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG401_RS05930	COG4195	phage-related replication protein
LG401_RS05935	COG2856	Zn peptidase
LG401_RS05940	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG401_RS05940	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS05955	COG0306	phosphate transporter
LG401_RS05960	COG1392	Phosphate transport regulator
LG401_RS05970	COG0405	Gamma-glutamyltransferase
LG401_RS05980	COG3775	system Galactitol-specific IIC component
LG401_RS06000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG401_RS06005	COG0022	dehydrogenase e1 component
LG401_RS06005	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS06010	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS06015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG401_RS06020	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS06025	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS06030	COG2390	Transcriptional regulator
LG401_RS06040	COG0531	amino acid
LG401_RS06045	COG0346	lactoylglutathione lyase activity
LG401_RS06050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG401_RS06055	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG401_RS06060	COG2362	D-Aminopeptidase
LG401_RS06065	COG0601	transmembrane transport
LG401_RS06070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG401_RS06075	COG0444	Belongs to the ABC transporter superfamily
LG401_RS06080	COG4166	transmembrane transport
LG401_RS06085	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG401_RS06090	COG4948	Mandelate Racemase Muconate Lactonizing
LG401_RS06095	COG0791	NLP P60 protein
LG401_RS06100	COG4608	Belongs to the ABC transporter superfamily
LG401_RS06105	COG1834	amidinotransferase
LG401_RS06110	COG1607	acyl-coa hydrolase
LG401_RS06115	COG1695	Transcriptional regulator
LG401_RS06130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG401_RS06140	COG2076	Multidrug Resistance protein
LG401_RS06145	COG2076	Multidrug Resistance protein
LG401_RS06155	COG0788	formyltetrahydrofolate deformylase activity
LG401_RS06160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LG401_RS06165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LG401_RS06170	COG0457	Tetratricopeptide repeat
LG401_RS06180	COG1764	response to oxidative stress
LG401_RS06185	COG1846	Transcriptional regulator
LG401_RS06190	COG1764	response to oxidative stress
LG401_RS06195	COG0590	tRNA wobble adenosine to inosine editing
LG401_RS06200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LG401_RS06205	COG1404	Belongs to the peptidase S8 family
LG401_RS06210	COG0745	RESPONSE REGULATOR receiver
LG401_RS06215	COG5002	protein histidine kinase activity
LG401_RS06215	COG3850	Histidine kinase
LG401_RS06220	COG3212	peptidase
LG401_RS06225	COG3212	peptidase
LG401_RS06235	COG2239	Acts as a magnesium transporter
LG401_RS06245	COG0583	DNA-binding transcription factor activity
LG401_RS06255	COG0789	Transcriptional regulator
LG401_RS06270	COG1846	Transcriptional regulator
LG401_RS06275	COG5001	Diguanylate cyclase
LG401_RS06275	COG3300	MHYT domain
LG401_RS06280	COG0586	Pfam SNARE associated Golgi protein
LG401_RS06285	COG0861	Integral membrane protein TerC family
LG401_RS06290	COG1191	sigma factor activity
LG401_RS06310	COG0501	Belongs to the peptidase M48B family
LG401_RS06315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LG401_RS06320	COG2323	membrane
LG401_RS06335	COG3594	Acyltransferase
LG401_RS06340	COG5002	protein histidine kinase activity
LG401_RS06345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LG401_RS06350	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LG401_RS06355	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LG401_RS06360	COG0436	Aminotransferase
LG401_RS06365	COG1850	ribulose-bisphosphate carboxylase activity
LG401_RS06370	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LG401_RS06375	COG0235	Class ii aldolase
LG401_RS06380	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LG401_RS06390	COG3852	Histidine kinase
LG401_RS06395	COG1846	Transcriptional regulator
LG401_RS06400	COG1360	Flagellar Motor Protein
LG401_RS06405	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LG401_RS06410	COG0542	response to heat
LG401_RS06415	COG3949	Membrane
LG401_RS06420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LG401_RS06425	COG0720	synthase
LG401_RS06430	COG0602	queuosine metabolic process
LG401_RS06435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LG401_RS06445	COG4873	Protein conserved in bacteria
LG401_RS06455	COG3773	Cell wall hydrolase
LG401_RS06460	COG2244	polysaccharide biosynthetic process
LG401_RS06465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS06470	COG2217	Heavy metal translocating P-type atpase
LG401_RS06475	COG0006	proline dipeptidase activity
LG401_RS06485	COG1609	Transcriptional regulator
LG401_RS06490	COG3711	transcriptional antiterminator
LG401_RS06495	COG1263	PTS System
LG401_RS06495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS06495	COG2190	(PTS) system
LG401_RS06500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS06505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LG401_RS06515	COG1533	DNA photolyase activity
LG401_RS06520	COG0840	transmembrane signaling receptor activity
LG401_RS06530	COG2084	Dehydrogenase
LG401_RS06535	COG2340	Cysteine-rich secretory protein family
LG401_RS06540	COG0768	penicillin binding
LG401_RS06545	COG4191	Histidine kinase
LG401_RS06550	COG0436	Aminotransferase
LG401_RS06555	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LG401_RS06565	COG1714	RDD family
LG401_RS06575	COG0784	Response regulator, receiver
LG401_RS06575	COG0835	chemotaxis
LG401_RS06590	COG2814	Major facilitator Superfamily
LG401_RS06595	COG1376	ErfK ybiS ycfS ynhG family protein
LG401_RS06600	COG1408	metallophosphoesterase
LG401_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS06610	COG2200	EAL domain
LG401_RS06615	COG3546	catalase activity
LG401_RS06620	COG4703	Protein of unknown function (DUF1797)
LG401_RS06625	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LG401_RS06635	COG0517	IMP dehydrogenase activity
LG401_RS06640	COG0583	DNA-binding transcription factor activity
LG401_RS06650	COG0716	FMN binding
LG401_RS06660	COG0716	FMN binding
LG401_RS06665	COG2171	N-acyltransferase activity
LG401_RS06670	COG1473	amidohydrolase
LG401_RS06680	COG0668	transmembrane transport
LG401_RS06685	COG0450	alkyl hydroperoxide reductase
LG401_RS06690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS06705	COG0746	molybdenum cofactor guanylyltransferase activity
LG401_RS06710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LG401_RS06715	COG0303	'Molybdopterin
LG401_RS06720	COG1763	Mo-molybdopterin cofactor biosynthetic process
LG401_RS06725	COG0314	molybdopterin synthase activity
LG401_RS06730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LG401_RS06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LG401_RS06750	COG1136	(ABC) transporter
LG401_RS06755	COG0577	efflux transmembrane transporter activity
LG401_RS06760	COG1349	DNA-binding transcription factor activity
LG401_RS06765	COG1105	Belongs to the carbohydrate kinase PfkB family
LG401_RS06770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS06770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS06775	COG0681	Belongs to the peptidase S26 family
LG401_RS06785	COG0488	(ABC) transporter
LG401_RS06790	COG2309	aminopeptidase activity
LG401_RS06800	COG1077	Cell shape determining protein MreB Mrl
LG401_RS06805	COG2002	toxin-antitoxin pair type II binding
LG401_RS06810	COG3852	Histidine kinase
LG401_RS06815	COG2105	PFAM AIG2 family protein
LG401_RS06815	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LG401_RS06820	COG0569	domain protein
LG401_RS06825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LG401_RS06830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LG401_RS06835	COG5503	Protein of unknown function (DUF1447)
LG401_RS06840	COG0561	phosphatase activity
LG401_RS06845	COG0242	peptide deformylase activity
LG401_RS06860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG401_RS06865	COG0022	dehydrogenase e1 component
LG401_RS06870	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS06875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG401_RS06880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS06890	COG1982	Orn Lys Arg decarboxylase major
LG401_RS06895	COG4476	Belongs to the UPF0223 family
LG401_RS06900	COG4493	Belongs to the UPF0637 family
LG401_RS06910	COG0483	inositol monophosphate 1-phosphatase activity
LG401_RS06925	COG1595	DNA-templated transcription, initiation
LG401_RS06945	COG1217	gtp-binding protein TYPA
LG401_RS06955	COG4896	Protein conserved in bacteria
LG401_RS06965	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LG401_RS06970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LG401_RS06975	COG2066	Belongs to the glutaminase family
LG401_RS06980	COG4838	Belongs to the UPF0358 family
LG401_RS06985	COG0772	Belongs to the SEDS family
LG401_RS06990	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LG401_RS06995	COG0415	Belongs to the DNA photolyase family
LG401_RS07000	COG1612	heme a metabolic process
LG401_RS07005	COG0109	protoheme IX farnesyltransferase activity
LG401_RS07010	COG2010	Cytochrome c
LG401_RS07010	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG401_RS07015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG401_RS07020	COG1845	cytochrome c oxidase, subunit III
LG401_RS07025	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG401_RS07030	COG3336	cytochrome c oxidase
LG401_RS07040	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LG401_RS07045	COG2340	Cysteine-rich secretory protein family
LG401_RS07065	COG3679	Belongs to the UPF0342 family
LG401_RS07070	COG4471	UPF0298 protein
LG401_RS07075	COG0742	ribosomal rna small subunit methyltransferase
LG401_RS07080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LG401_RS07085	COG3314	Sporulation integral membrane protein YlbJ
LG401_RS07090	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG401_RS07095	COG3480	Lon protease (S16) C-terminal proteolytic domain
LG401_RS07105	COG1399	metal-binding, possibly nucleic acid-binding protein
LG401_RS07110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LG401_RS07120	COG0454	-acetyltransferase
LG401_RS07125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LG401_RS07130	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LG401_RS07135	COG2001	Belongs to the MraZ family
LG401_RS07140	COG0275	rRNA processing
LG401_RS07145	COG4839	cell division protein FtsL
LG401_RS07150	COG0768	penicillin binding
LG401_RS07155	COG0768	penicillin binding
LG401_RS07160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LG401_RS07165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LG401_RS07170	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LG401_RS07175	COG0772	Belongs to the SEDS family
LG401_RS07180	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LG401_RS07185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LG401_RS07190	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LG401_RS07195	COG3879	Bacterial protein of unknown function (DUF881)
LG401_RS07200	COG3879	Bacterial protein of unknown function (DUF881)
LG401_RS07205	COG3856	small basic protein
LG401_RS07210	COG0849	cell division
LG401_RS07215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LG401_RS07220	COG1404	Belongs to the peptidase S8 family
LG401_RS07220	COG4412	M6 family metalloprotease domain protein
LG401_RS07230	COG1191	sigma factor activity
LG401_RS07235	COG1191	sigma factor activity
LG401_RS07240	COG2390	Transcriptional regulator
LG401_RS07255	COG3730	PTS system glucitol sorbitol-specific
LG401_RS07260	COG3732	PTS system glucitol sorbitol-specific
LG401_RS07270	COG1119	ATPase activity
LG401_RS07275	COG1873	PFAM PRC-barrel domain
LG401_RS07280	COG1496	oxidoreductase activity
LG401_RS07285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LG401_RS07290	COG1799	cell septum assembly
LG401_RS07295	COG0762	integral membrane protein
LG401_RS07300	COG2302	S4 RNA-binding domain
LG401_RS07305	COG3599	regulation of cell shape
LG401_RS07310	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LG401_RS07315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG401_RS07320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LG401_RS07325	COG0564	pseudouridine synthase activity
LG401_RS07330	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LG401_RS07335	COG2233	PERMEase
LG401_RS07340	COG0540	Belongs to the ATCase OTCase family
LG401_RS07345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LG401_RS07350	COG0505	Belongs to the CarA family
LG401_RS07355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LG401_RS07360	COG0543	2 iron, 2 sulfur cluster binding
LG401_RS07365	COG0167	dihydroorotate dehydrogenase activity
LG401_RS07370	COG0284	orotidine-5'-phosphate decarboxylase activity
LG401_RS07375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LG401_RS07385	COG0175	sulfate reduction
LG401_RS07390	COG0306	phosphate transporter
LG401_RS07395	COG2046	Belongs to the sulfate adenylyltransferase family
LG401_RS07400	COG0529	Catalyzes the synthesis of activated sulfate
LG401_RS07405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LG401_RS07410	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
LG401_RS07415	COG1648	precorrin-2 dehydrogenase activity
LG401_RS07425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LG401_RS07430	COG1561	YicC-like family, N-terminal region
LG401_RS07435	COG2052	Domain of unknown function (DUF370)
LG401_RS07440	COG0194	GDP metabolic process
LG401_RS07445	COG1758	RNA polymerase activity
LG401_RS07450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG401_RS07455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LG401_RS07460	COG0242	peptide deformylase activity
LG401_RS07465	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LG401_RS07470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LG401_RS07470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG401_RS07475	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LG401_RS07480	COG0631	protein serine/threonine phosphatase activity
LG401_RS07485	COG0515	serine threonine protein kinase
LG401_RS07485	COG2815	serine threonine protein kinase
LG401_RS07490	COG1162	GTPase activity
LG401_RS07495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LG401_RS07500	COG1564	THIamine pyrophosphokinase
LG401_RS07510	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LG401_RS07515	COG1302	Protein conserved in bacteria
LG401_RS07520	COG1461	Dihydroxyacetone kinase
LG401_RS07525	COG1760	l-serine dehydratase
LG401_RS07530	COG1760	l-serine dehydratase
LG401_RS07535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LG401_RS07540	COG1349	DNA-binding transcription factor activity
LG401_RS07545	COG0416	fatty acid biosynthetic process
LG401_RS07550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LG401_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS07560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LG401_RS07570	COG1196	nuclear chromosome segregation
LG401_RS07575	COG0552	protein localization to endoplasmic reticulum
LG401_RS07580	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LG401_RS07585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LG401_RS07590	COG0228	four-way junction DNA binding
LG401_RS07595	COG1837	Belongs to the UPF0109 family
LG401_RS07605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LG401_RS07610	COG0336	Belongs to the RNA methyltransferase TrmD family
LG401_RS07615	COG0335	large ribosomal subunit rRNA binding
LG401_RS07620	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LG401_RS07625	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LG401_RS07635	COG2257	FlhB HrpN YscU SpaS Family
LG401_RS07640	COG0045	succinate-CoA ligase (ADP-forming) activity
LG401_RS07645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LG401_RS07650	COG0758	DNA mediated transformation
LG401_RS07655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LG401_RS07660	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LG401_RS07665	COG4974	Belongs to the 'phage' integrase family
LG401_RS07670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LG401_RS07675	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LG401_RS07680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LG401_RS07685	COG1815	bacterial-type flagellum-dependent cell motility
LG401_RS07690	COG1558	bacterial-type flagellum-dependent cell motility
LG401_RS07695	COG1677	Flagellar hook-basal body complex protein FliE
LG401_RS07700	COG1766	The M ring may be actively involved in energy transduction
LG401_RS07705	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG401_RS07710	COG1317	bacterial-type flagellum organization
LG401_RS07715	COG1157	protein secretion by the type III secretion system
LG401_RS07720	COG2882	bacterial-type flagellum organization
LG401_RS07725	COG3334	PFAM MgtE intracellular
LG401_RS07730	COG3144	bacterial-type flagellum assembly
LG401_RS07735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LG401_RS07740	COG4786	Flagellar basal body rod
LG401_RS07745	COG1582	Flagellar protein (FlbD)
LG401_RS07750	COG1580	Controls the rotational direction of flagella during chemotaxis
LG401_RS07755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG401_RS07760	COG1776	CheC inhibitor of MCP methylation
LG401_RS07760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LG401_RS07765	COG2201	protein-glutamate methylesterase activity
LG401_RS07770	COG3190	flagellar
LG401_RS07775	COG1338	Plays a role in the flagellum-specific transport system
LG401_RS07780	COG1987	bacterial-type flagellum assembly
LG401_RS07785	COG1684	flagellar biosynthetic protein fliR
LG401_RS07790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LG401_RS07795	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LG401_RS07800	COG1419	protein localization to endoplasmic reticulum
LG401_RS07805	COG0455	bacterial-type flagellum organization
LG401_RS07810	COG2201	protein-glutamate methylesterase activity
LG401_RS07815	COG2198	Histidine kinase
LG401_RS07815	COG0643	Histidine kinase
LG401_RS07820	COG0835	chemotaxis
LG401_RS07825	COG1776	CheC inhibitor of MCP methylation
LG401_RS07835	COG1191	sigma factor activity
LG401_RS07845	COG0052	Belongs to the universal ribosomal protein uS2 family
LG401_RS07850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LG401_RS07855	COG0528	UMP kinase activity
LG401_RS07860	COG0233	cytoplasmic translational termination
LG401_RS07865	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LG401_RS07870	COG4589	Belongs to the CDS family
LG401_RS07875	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LG401_RS07880	COG0750	zinc metalloprotease
LG401_RS07885	COG0442	prolyl-tRNA aminoacylation
LG401_RS07890	COG2176	DNA-directed DNA polymerase activity
LG401_RS07905	COG3693	PFAM glycoside hydrolase, family 10
LG401_RS07915	COG0779	Required for maturation of 30S ribosomal subunits
LG401_RS07920	COG0195	Participates in both transcription termination and antitermination
LG401_RS07925	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LG401_RS07930	COG1358	cellular component organization or biogenesis
LG401_RS07935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LG401_RS07940	COG1550	Protein conserved in bacteria
LG401_RS07945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LG401_RS07950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LG401_RS07955	COG0196	riboflavin kinase activity
LG401_RS07960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LG401_RS07965	COG1185	polyribonucleotide nucleotidyltransferase activity
LG401_RS07970	COG0726	polysaccharide deacetylase
LG401_RS07975	COG0612	Peptidase, M16
LG401_RS07985	COG1873	PFAM PRC-barrel domain
LG401_RS07990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG401_RS07995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LG401_RS08000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LG401_RS08005	COG0527	aspartate kinase activity
LG401_RS08015	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LG401_RS08020	COG0740	serine-type endopeptidase activity
LG401_RS08030	COG1674	ftsk spoiiie
LG401_RS08030	COG4980	gas vesicle protein
LG401_RS08035	COG2188	Transcriptional regulator
LG401_RS08040	COG2814	Major facilitator Superfamily
LG401_RS08045	COG1033	growth of symbiont in host cell
LG401_RS08045	COG2409	Drug exporters of the RND superfamily
LG401_RS08050	COG0612	Peptidase, M16
LG401_RS08065	COG1033	growth of symbiont in host cell
LG401_RS08065	COG2409	Drug exporters of the RND superfamily
LG401_RS08070	COG0300	oxidoreductase activity
LG401_RS08085	COG1426	Protein conserved in bacteria
LG401_RS08090	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LG401_RS08095	COG1546	Belongs to the CinA family
LG401_RS08095	COG1058	Belongs to the CinA family
LG401_RS08100	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LG401_RS08105	COG1418	mRNA catabolic process
LG401_RS08110	COG1692	metallophosphoesterase
LG401_RS08115	COG2359	stage V sporulation protein S
LG401_RS08120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LG401_RS08125	COG1063	alcohol dehydrogenase
LG401_RS08130	COG0156	8-amino-7-oxononanoate synthase activity
LG401_RS08135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LG401_RS08140	COG4550	Control of competence regulator ComK, YlbF/YmcA
LG401_RS08150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LG401_RS08155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LG401_RS08170	COG1329	Transcriptional regulator
LG401_RS08175	COG4195	phage-related replication protein
LG401_RS08180	COG0457	Tetratricopeptide repeat
LG401_RS08185	COG1404	Belongs to the peptidase S8 family
LG401_RS08190	COG4195	phage-related replication protein
LG401_RS08195	COG1764	response to oxidative stress
LG401_RS08200	COG2076	Multidrug Resistance protein
LG401_RS08225	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LG401_RS08230	COG1923	regulation of RNA biosynthetic process
LG401_RS08245	COG1780	Probably involved in ribonucleotide reductase function
LG401_RS08250	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG401_RS08255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LG401_RS08260	COG4112	unkown
LG401_RS08270	COG0464	growth
LG401_RS08275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LG401_RS08280	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LG401_RS08285	COG0789	Transcriptional regulator
LG401_RS08290	COG0174	glutamine synthetase
LG401_RS08295	COG0457	Tetratricopeptide repeat
LG401_RS08300	COG5444	nuclease activity
LG401_RS08325	COG5646	InterPro IPR014922
LG401_RS08350	COG0457	Tetratricopeptide repeat
LG401_RS08360	COG3619	membrane
LG401_RS08365	COG3285	dna ligase
LG401_RS08365	COG1793	dna ligase
LG401_RS08370	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LG401_RS08375	COG4876	unkown
LG401_RS08385	COG1959	2 iron, 2 sulfur cluster binding
LG401_RS08390	COG0702	epimerase
LG401_RS08395	COG0247	lactate metabolic process
LG401_RS08400	COG1139	Iron-sulfur cluster binding protein
LG401_RS08405	COG1556	Lactate utilization protein
LG401_RS08425	COG1309	transcriptional regulator
LG401_RS08430	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG401_RS08430	COG2124	cytochrome p450
LG401_RS08435	COG3591	Belongs to the peptidase S1B family
LG401_RS08440	COG3209	COG3209 Rhs family protein
LG401_RS08445	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS08460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LG401_RS08465	COG1388	LysM domain
LG401_RS08470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LG401_RS08475	COG4224	UPF0291 protein
LG401_RS08480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LG401_RS08490	COG3763	UPF0154 protein
LG401_RS08515	COG0071	Belongs to the small heat shock protein (HSP20) family
LG401_RS08530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LG401_RS08535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS08555	COG0824	Thioesterase
LG401_RS08565	COG4841	protein insertion into membrane
LG401_RS08570	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LG401_RS08575	COG1832	CoA-binding protein
LG401_RS08580	COG0187	DNA topoisomerase II activity
LG401_RS08585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LG401_RS08595	COG0738	Major facilitator superfamily
LG401_RS08600	COG0473	3-isopropylmalate dehydrogenase activity
LG401_RS08620	COG1733	regulation of RNA biosynthetic process
LG401_RS08630	COG0583	DNA-binding transcription factor activity
LG401_RS08645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG401_RS08650	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LG401_RS08655	COG0640	Transcriptional regulator
LG401_RS08660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG401_RS08665	COG0251	oxidation-reduction process
LG401_RS08695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LG401_RS08715	COG0657	acetylesterase activity
LG401_RS08720	COG0789	Transcriptional regulator
LG401_RS08725	COG2723	6-phospho-beta-galactosidase activity
LG401_RS08730	COG2190	(PTS) system
LG401_RS08730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS08730	COG1263	PTS System
LG401_RS08745	COG2205	protein histidine kinase activity
LG401_RS08750	COG0745	RESPONSE REGULATOR receiver
LG401_RS08760	COG3507	Belongs to the glycosyl hydrolase 43 family
LG401_RS08765	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS08770	COG1486	melibiose metabolic process
LG401_RS08775	COG0395	ABC-type sugar transport system, permease component
LG401_RS08780	COG1175	transmembrane transport
LG401_RS08785	COG1653	transport
LG401_RS08790	COG1609	Transcriptional regulator
LG401_RS08795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LG401_RS08810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS08820	COG5444	nuclease activity
LG401_RS08825	COG1846	Transcriptional regulator
LG401_RS08830	COG2814	Major facilitator Superfamily
LG401_RS08840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS08840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS08840	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS08845	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS08845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS08845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LG401_RS08850	COG1105	Belongs to the carbohydrate kinase PfkB family
LG401_RS08860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG401_RS08890	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LG401_RS08895	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG401_RS08900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG401_RS08905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG401_RS08910	COG1024	Enoyl-CoA hydratase
LG401_RS08915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG401_RS08920	COG0511	ligase activity, forming carbon-carbon bonds
LG401_RS08925	COG0439	Biotin carboxylase
LG401_RS08930	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS08935	COG1960	acyl-CoA dehydrogenase activity
LG401_RS08940	COG1649	PFAM Uncharacterised BCR, COG1649
LG401_RS08945	COG2365	Tyrosine phosphatase family
LG401_RS08950	COG1349	DNA-binding transcription factor activity
LG401_RS08960	COG3835	regulator
LG401_RS08965	COG0277	FAD linked oxidase domain protein
LG401_RS08970	COG0247	lactate metabolic process
LG401_RS08995	COG0166	Belongs to the GPI family
LG401_RS09000	COG0586	Pfam SNARE associated Golgi protein
LG401_RS09005	COG1587	Uroporphyrinogen-III synthase
LG401_RS09015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG401_RS09035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG401_RS09040	COG1846	Transcriptional regulator
LG401_RS09050	COG2085	NADP oxidoreductase coenzyme F420-dependent
LG401_RS09070	COG0534	Mate efflux family protein
LG401_RS09075	COG2027	D-alanyl-D-alanine carboxypeptidase
LG401_RS09080	COG4677	pectinesterase activity
LG401_RS09085	COG2323	membrane
LG401_RS09090	COG2146	nitrite reductase [NAD(P)H] activity
LG401_RS09095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG401_RS09100	COG0243	molybdopterin cofactor binding
LG401_RS09105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LG401_RS09110	COG2223	nitrite transmembrane transporter activity
LG401_RS09115	COG0493	'glutamate synthase
LG401_RS09120	COG0067	glutamate synthase
LG401_RS09120	COG0069	glutamate synthase activity
LG401_RS09120	COG0070	glutamate synthase
LG401_RS09125	COG0583	DNA-binding transcription factor activity
LG401_RS09145	COG0454	-acetyltransferase
LG401_RS09150	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LG401_RS09155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LG401_RS09170	COG0243	molybdopterin cofactor binding
LG401_RS09180	COG1070	Carbohydrate kinase
LG401_RS09185	COG2115	Belongs to the xylose isomerase family
LG401_RS09190	COG1940	carbohydrate kinase activity
LG401_RS09200	COG2211	Major facilitator Superfamily
LG401_RS09205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG401_RS09210	COG1994	Peptidase M50
LG401_RS09230	COG1309	transcriptional regulator
LG401_RS09235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS09240	COG3708	Transcriptional regulator
LG401_RS09245	COG2378	regulation of single-species biofilm formation
LG401_RS09255	COG0640	Transcriptional regulator
LG401_RS09260	COG0531	amino acid
LG401_RS09265	COG0741	lytic transglycosylase activity
LG401_RS09270	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LG401_RS09275	COG2079	MmgE PrpD family protein
LG401_RS09280	COG0372	Belongs to the citrate synthase family
LG401_RS09285	COG2322	membrane
LG401_RS09295	COG1388	LysM domain
LG401_RS09295	COG3584	3D domain protein
LG401_RS09300	COG0514	ATP-dependent DNA helicase (RecQ)
LG401_RS09310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG401_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS09340	COG1657	PFAM Prenyltransferase squalene oxidase
LG401_RS09345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LG401_RS09350	COG0385	Bile acid
LG401_RS09355	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS09360	COG0567	Dehydrogenase, E1 component
LG401_RS09365	COG4548	von Willebrand factor, type A
LG401_RS09370	COG0714	Associated with various cellular activities
LG401_RS09375	COG2032	superoxide dismutase activity
LG401_RS09380	COG0791	NLP P60 protein
LG401_RS09380	COG1388	LysM domain
LG401_RS09385	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LG401_RS09390	COG0534	Mate efflux family protein
LG401_RS09395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG401_RS09400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG401_RS09410	COG2962	Rard protein
LG401_RS09425	COG1733	regulation of RNA biosynthetic process
LG401_RS09430	COG0778	Nitroreductase
LG401_RS09440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG401_RS09445	COG0793	Belongs to the peptidase S41A family
LG401_RS09445	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS09450	COG2226	methyltransferase
LG401_RS09460	COG1876	peptidase activity
LG401_RS09465	COG0813	purine-nucleoside phosphorylase activity
LG401_RS09475	COG0671	phosphoesterase, PA-phosphatase related
LG401_RS09490	COG4479	Belongs to the UPF0346 family
LG401_RS09500	COG1509	lysine 2,3-aminomutase activity
LG401_RS09505	COG3829	transcription factor binding
LG401_RS09510	COG0463	Glycosyl transferase, family 2
LG401_RS09525	COG4641	Protein conserved in bacteria
LG401_RS09535	COG1086	Polysaccharide biosynthesis protein
LG401_RS09540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG401_RS09545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LG401_RS09550	COG1846	Transcriptional regulator
LG401_RS09570	COG4698	Protein conserved in bacteria
LG401_RS09575	COG2755	lipolytic protein G-D-S-L family
LG401_RS09580	COG1999	signal sequence binding
LG401_RS09595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LG401_RS09600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LG401_RS09605	COG1272	protein, Hemolysin III
LG401_RS09610	COG0204	Acyl-transferase
LG401_RS09615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LG401_RS09620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LG401_RS09625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LG401_RS09635	COG2136	Putative SAM-dependent methyltransferase
LG401_RS09635	COG2521	methyltransferase
LG401_RS09645	COG0129	dihydroxy-acid dehydratase activity
LG401_RS09650	COG1413	lyase activity
LG401_RS09655	COG1418	mRNA catabolic process
LG401_RS09660	COG0386	Belongs to the glutathione peroxidase family
LG401_RS09665	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LG401_RS09670	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LG401_RS09675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LG401_RS09685	COG1278	Cold shock
LG401_RS09700	COG0328	RNA-DNA hybrid ribonuclease activity
LG401_RS09705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LG401_RS09710	COG0328	RNA-DNA hybrid ribonuclease activity
LG401_RS09720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG401_RS09730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LG401_RS09740	COG1755	Isoprenylcysteine carboxyl methyltransferase
LG401_RS09745	COG3424	synthase
LG401_RS09750	COG2233	PERMEase
LG401_RS09755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG401_RS09760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LG401_RS09765	COG1199	ATP-dependent helicase activity
LG401_RS09775	COG0116	Belongs to the methyltransferase superfamily
LG401_RS09785	COG3599	regulation of cell shape
LG401_RS09790	COG4474	Belongs to the UPF0398 family
LG401_RS09800	COG3359	exonuclease
LG401_RS09805	COG1205	dead DEAH box helicase
LG401_RS09805	COG1111	helicase
LG401_RS09810	COG1902	pentaerythritol trinitrate reductase activity
LG401_RS09815	COG2190	(PTS) system
LG401_RS09820	COG0071	Belongs to the small heat shock protein (HSP20) family
LG401_RS09850	COG3331	DNA recombination
LG401_RS09855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG401_RS09855	COG4499	WXG100 protein secretion system (Wss), protein YukC
LG401_RS09865	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LG401_RS09870	COG3935	DnaD domain protein
LG401_RS09875	COG0017	Asparaginyl-tRNA synthetase
LG401_RS09880	COG5353	protein conserved in bacteria
LG401_RS09890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LG401_RS09890	COG1199	ATP-dependent helicase activity
LG401_RS09895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LG401_RS09900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LG401_RS09905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LG401_RS09915	COG0617	tRNA 3'-terminal CCA addition
LG401_RS09920	COG0438	transferase activity, transferring glycosyl groups
LG401_RS09925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LG401_RS09930	COG1803	Methylglyoxal synthase
LG401_RS09935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LG401_RS09940	COG1694	Mazg nucleotide pyrophosphohydrolase
LG401_RS09945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG401_RS09955	COG4347	Protein of unknown function (DUF1405)
LG401_RS09960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LG401_RS09960	COG2010	Cytochrome c
LG401_RS09965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LG401_RS09970	COG0723	plastoquinol--plastocyanin reductase activity
LG401_RS09980	COG5582	Belongs to the UPF0302 family
LG401_RS09985	COG0457	Tetratricopeptide repeat
LG401_RS09990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LG401_RS09995	COG0287	Prephenate dehydrogenase
LG401_RS10000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LG401_RS10005	COG0159	tryptophan synthase activity
LG401_RS10010	COG0133	tryptophan synthase activity
LG401_RS10015	COG0135	phosphoribosylanthranilate isomerase activity
LG401_RS10020	COG0134	indole-3-glycerol-phosphate synthase activity
LG401_RS10025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LG401_RS10035	COG4401	Chorismate mutase type I
LG401_RS10040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LG401_RS10045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LG401_RS10050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LG401_RS10055	COG0105	UTP biosynthetic process
LG401_RS10060	COG0142	geranyltranstransferase activity
LG401_RS10065	COG2226	methyltransferase
LG401_RS10070	COG0142	geranyltranstransferase activity
LG401_RS10080	COG0302	gtp cyclohydrolase
LG401_RS10085	COG0776	regulation of translation
LG401_RS10090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LG401_RS10105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LG401_RS10110	COG1160	GTP binding
LG401_RS10135	COG1304	FMN binding
LG401_RS10140	COG0539	negative regulation of cytoplasmic translation
LG401_RS10145	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LG401_RS10155	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
LG401_RS10160	COG2959	enzyme of heme biosynthesis
LG401_RS10165	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS10165	COG3773	Cell wall hydrolase
LG401_RS10170	COG2339	peptidase activity
LG401_RS10175	COG0492	ferredoxin-NADP+ reductase activity
LG401_RS10180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG401_RS10185	COG4862	establishment of competence for transformation
LG401_RS10190	COG1408	metallophosphoesterase
LG401_RS10200	COG1388	LysM domain
LG401_RS10205	COG1266	CAAX protease self-immunity
LG401_RS10210	COG0514	ATP-dependent DNA helicase (RecQ)
LG401_RS10215	COG4955	Helix-turn-helix domain
LG401_RS10220	COG1141	Ferredoxin
LG401_RS10225	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LG401_RS10230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LG401_RS10235	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG401_RS10235	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS10245	COG1595	DNA-templated transcription, initiation
LG401_RS10250	COG5002	protein histidine kinase activity
LG401_RS10255	COG0745	RESPONSE REGULATOR receiver
LG401_RS10260	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LG401_RS10265	COG1333	cytochrome c biogenesis protein
LG401_RS10270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS10275	COG1187	pseudouridine synthase activity
LG401_RS10280	COG0700	Nucleoside recognition
LG401_RS10285	COG2715	membrane protein required for spore maturation
LG401_RS10290	COG1686	Belongs to the peptidase S11 family
LG401_RS10300	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LG401_RS10305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LG401_RS10315	COG1547	Domain of unknown function (DUF309)
LG401_RS10320	COG0456	acetyltransferase
LG401_RS10325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LG401_RS10335	COG0307	riboflavin synthase, alpha
LG401_RS10355	COG2814	Major facilitator Superfamily
LG401_RS10360	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LG401_RS10365	COG4086	secreted protein
LG401_RS10370	COG0019	diaminopimelate decarboxylase activity
LG401_RS10375	COG0697	spore germination
LG401_RS10390	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LG401_RS10410	COG1191	sigma factor activity
LG401_RS10415	COG2172	sigma factor antagonist activity
LG401_RS10425	COG1686	Belongs to the peptidase S11 family
LG401_RS10430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LG401_RS10435	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LG401_RS10440	COG4974	Belongs to the 'phage' integrase family
LG401_RS10450	COG0735	belongs to the Fur family
LG401_RS10455	COG1300	Membrane
LG401_RS10460	COG1404	Belongs to the peptidase S8 family
LG401_RS10470	COG2153	protein acetylation
LG401_RS10475	COG1379	DNA repair
LG401_RS10480	COG0494	nUDIX hydrolase
LG401_RS10485	COG0667	Aldo Keto reductase
LG401_RS10500	COG1073	alpha beta
LG401_RS10505	COG0457	Tetratricopeptide repeat
LG401_RS10515	COG4918	Iron-sulphur cluster biosynthesis
LG401_RS10520	COG4305	rare lipoprotein A
LG401_RS10525	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LG401_RS10525	COG0456	acetyltransferase
LG401_RS10530	COG0456	acetyltransferase
LG401_RS10540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG401_RS10550	COG2211	Major facilitator Superfamily
LG401_RS10555	COG1072	(Pantothenic acid kinase))
LG401_RS10560	COG0446	pyridine nucleotide-disulphide oxidoreductase
LG401_RS10565	COG0300	oxidoreductase activity
LG401_RS10570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS10575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG401_RS10585	COG4187	Peptidase family M20/M25/M40
LG401_RS10590	COG1902	pentaerythritol trinitrate reductase activity
LG401_RS10595	COG0596	Alpha beta hydrolase
LG401_RS10600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LG401_RS10605	COG1234	tRNA 3'-trailer cleavage
LG401_RS10610	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LG401_RS10615	COG2188	Transcriptional regulator
LG401_RS10620	COG2723	6-phospho-beta-galactosidase activity
LG401_RS10625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS10630	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG401_RS10635	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS10640	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS10645	COG4975	Glucose uptake
LG401_RS10650	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LG401_RS10655	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LG401_RS10665	COG0706	membrane insertase activity
LG401_RS10675	COG2195	Cleaves the N-terminal amino acid of tripeptides
LG401_RS10680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LG401_RS10685	COG0346	lactoylglutathione lyase activity
LG401_RS10695	COG1376	ErfK ybiS ycfS ynhG family protein
LG401_RS10700	COG4129	membrane
LG401_RS10705	COG1126	abc transporter atp-binding protein
LG401_RS10710	COG0765	amino acid transport
LG401_RS10715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS10725	COG1597	lipid kinase activity
LG401_RS10735	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS10740	COG0022	dehydrogenase e1 component
LG401_RS10745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LG401_RS10750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LG401_RS10755	COG3426	butyrate kinase activity
LG401_RS10760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG401_RS10765	COG0280	phosphate acetyltransferase
LG401_RS10770	COG3290	protein histidine kinase activity
LG401_RS10770	COG3829	transcription factor binding
LG401_RS10780	COG0584	glycerophosphoryl diester phosphodiesterase
LG401_RS10785	COG0457	Tetratricopeptide repeat
LG401_RS10790	COG0745	RESPONSE REGULATOR receiver
LG401_RS10795	COG0750	zinc metalloprotease
LG401_RS10800	COG0497	DNA recombination
LG401_RS10805	COG1438	arginine binding
LG401_RS10810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LG401_RS10815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LG401_RS10820	COG0142	geranyltranstransferase activity
LG401_RS10825	COG1722	exodeoxyribonuclease VII activity
LG401_RS10830	COG1570	exodeoxyribonuclease VII activity
LG401_RS10835	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LG401_RS10840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LG401_RS10845	COG1302	Protein conserved in bacteria
LG401_RS10850	COG0439	Biotin carboxylase
LG401_RS10855	COG0511	ligase activity, forming carbon-carbon bonds
LG401_RS10895	COG3854	ATPases associated with a variety of cellular activities
LG401_RS10905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LG401_RS10910	COG0006	proline dipeptidase activity
LG401_RS10915	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LG401_RS10925	COG3872	metal-dependent enzyme
LG401_RS10935	COG1752	Esterase of the alpha-beta hydrolase superfamily
LG401_RS10940	COG1321	iron dependent repressor
LG401_RS10945	COG0095	Lipoate-protein ligase
LG401_RS10950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG401_RS10955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG401_RS10960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LG401_RS10965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LG401_RS10970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LG401_RS10995	COG0681	Belongs to the peptidase S26 family
LG401_RS11030	COG4970	Tfp pilus assembly protein FimT
LG401_RS11035	COG4537	Required for transformation and DNA binding
LG401_RS11040	COG1459	type II secretion system
LG401_RS11045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LG401_RS11050	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS11060	COG1393	Belongs to the ArsC family
LG401_RS11070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS11080	COG0011	TIGRFAM Protein of
LG401_RS11085	COG2814	Major facilitator Superfamily
LG401_RS11090	COG2866	Carboxypeptidase
LG401_RS11095	COG1368	sulfuric ester hydrolase activity
LG401_RS11100	COG1940	carbohydrate kinase activity
LG401_RS11105	COG4483	Protein conserved in bacteria
LG401_RS11110	COG0705	Rhomboid family
LG401_RS11110	COG0457	Tetratricopeptide repeat
LG401_RS11120	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LG401_RS11125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG401_RS11135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG401_RS11140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LG401_RS11145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LG401_RS11150	COG0581	inorganic phosphate transmembrane transporter activity
LG401_RS11155	COG0573	inorganic phosphate transmembrane transporter activity
LG401_RS11160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LG401_RS11165	COG0768	penicillin binding
LG401_RS11170	COG0477	Major facilitator Superfamily
LG401_RS11175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LG401_RS11180	COG2839	Protein conserved in bacteria
LG401_RS11185	COG5521	maltodextrose utilization protein MalA
LG401_RS11190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LG401_RS11195	COG1388	LysM domain
LG401_RS11200	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LG401_RS11205	COG4709	membrane
LG401_RS11210	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LG401_RS11215	COG1940	carbohydrate kinase activity
LG401_RS11220	COG0735	belongs to the Fur family
LG401_RS11225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LG401_RS11230	COG1121	(ABC) transporter
LG401_RS11235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG401_RS11245	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LG401_RS11250	COG0513	Belongs to the DEAD box helicase family
LG401_RS11260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LG401_RS11265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LG401_RS11270	COG2384	SAM-dependent methyltransferase
LG401_RS11275	COG2010	Cytochrome c
LG401_RS11280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LG401_RS11285	COG0358	DNA primase activity
LG401_RS11290	COG1671	Belongs to the UPF0178 family
LG401_RS11295	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LG401_RS11300	COG0517	IMP dehydrogenase activity
LG401_RS11305	COG0751	glycine-tRNA ligase activity
LG401_RS11310	COG0752	glycyl-tRNA synthetase alpha subunit
LG401_RS11315	COG1381	Involved in DNA repair and RecF pathway recombination
LG401_RS11325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LG401_RS11330	COG0295	cytidine deaminase activity
LG401_RS11335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LG401_RS11340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LG401_RS11345	COG1480	7TM receptor with intracellular HD hydrolase
LG401_RS11350	COG1702	phosphate starvation-inducible protein PhoH
LG401_RS11355	COG0561	phosphatase activity
LG401_RS11370	COG4864	UPF0365 protein
LG401_RS11375	COG1030	water channel activity
LG401_RS11380	COG1610	YqeY-like protein
LG401_RS11390	COG1283	sodium-dependent phosphate transmembrane transporter activity
LG401_RS11395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LG401_RS11400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LG401_RS11405	COG2264	protein methyltransferase activity
LG401_RS11410	COG0484	heat shock protein binding
LG401_RS11415	COG0443	Heat shock 70 kDa protein
LG401_RS11420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LG401_RS11425	COG1420	regulation of RNA biosynthetic process
LG401_RS11430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LG401_RS11435	COG0481	GTPase activity
LG401_RS11445	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG401_RS11450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LG401_RS11455	COG0268	Binds directly to 16S ribosomal RNA
LG401_RS11460	COG1466	dna polymerase III delta subunit
LG401_RS11470	COG0658	competence protein
LG401_RS11470	COG2333	competence protein COMEC
LG401_RS11475	COG2131	deaminase
LG401_RS11480	COG1555	photosystem II stabilization
LG401_RS11485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LG401_RS11490	COG2226	methyltransferase
LG401_RS11495	COG0799	negative regulation of ribosome biogenesis
LG401_RS11500	COG1713	HD superfamily hydrolase involved in NAD metabolism
LG401_RS11505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LG401_RS11510	COG1534	Rna-binding protein
LG401_RS11515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LG401_RS11520	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LG401_RS11525	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LG401_RS11540	COG2755	lipolytic protein G-D-S-L family
LG401_RS11550	COG0457	Tetratricopeptide repeat
LG401_RS11565	COG4221	oxidoreductase activity
LG401_RS11570	COG0300	oxidoreductase activity
LG401_RS11575	COG1902	pentaerythritol trinitrate reductase activity
LG401_RS11580	COG0596	Alpha beta hydrolase
LG401_RS11580	COG0508	dehydrogenase complex catalyzes the overall conversion of
LG401_RS11585	COG1309	transcriptional regulator
LG401_RS11595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG401_RS11610	COG0726	polysaccharide deacetylase
LG401_RS11645	COG1122	ATPase activity
LG401_RS11665	COG2160	L-arabinose isomerase activity
LG401_RS11680	COG1609	Transcriptional regulator
LG401_RS11690	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LG401_RS11695	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LG401_RS11700	COG1733	regulation of RNA biosynthetic process
LG401_RS11705	COG0657	acetylesterase activity
LG401_RS11730	COG2602	Beta-lactamase
LG401_RS11735	COG1960	acyl-CoA dehydrogenase activity
LG401_RS11740	COG1126	abc transporter atp-binding protein
LG401_RS11745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS11750	COG0765	amino acid transport
LG401_RS11760	COG3546	catalase activity
LG401_RS11765	COG1063	alcohol dehydrogenase
LG401_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS11785	COG1115	amino acid carrier protein
LG401_RS11790	COG0583	DNA-binding transcription factor activity
LG401_RS11795	COG0842	Transport permease protein
LG401_RS11800	COG0842	Transport permease protein
LG401_RS11800	COG1511	domain protein
LG401_RS11805	COG1131	(ABC) transporter
LG401_RS11810	COG1091	dTDP-4-dehydrorhamnose reductase activity
LG401_RS11830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LG401_RS11835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LG401_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS11865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LG401_RS11875	COG1063	alcohol dehydrogenase
LG401_RS11880	COG2226	methyltransferase
LG401_RS11905	COG0626	cystathionine gamma-synthase activity
LG401_RS11910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG401_RS11915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LG401_RS11920	COG2226	methyltransferase
LG401_RS11935	COG0768	penicillin binding
LG401_RS11940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LG401_RS11945	COG0572	uridine kinase
LG401_RS11950	COG0826	peptidase U32
LG401_RS11955	COG0826	peptidase U32
LG401_RS11960	COG4122	O-methyltransferase activity
LG401_RS11965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LG401_RS11970	COG0183	Belongs to the thiolase family
LG401_RS11975	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS11980	COG1268	BioY protein
LG401_RS11985	COG3906	Belongs to the UPF0473 family
LG401_RS11990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LG401_RS11995	COG4472	Bacterial protein of unknown function (DUF965)
LG401_RS12000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LG401_RS12005	COG0628	permease
LG401_RS12010	COG1126	abc transporter atp-binding protein
LG401_RS12015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS12020	COG0765	amino acid transport
LG401_RS12025	COG0765	amino acid transport
LG401_RS12040	COG3881	PFAM PRC-barrel domain
LG401_RS12045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LG401_RS12050	COG0457	Tetratricopeptide repeat
LG401_RS12055	COG0482	sulfurtransferase activity
LG401_RS12060	COG1104	cysteine desulfurase activity
LG401_RS12065	COG1959	2 iron, 2 sulfur cluster binding
LG401_RS12070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LG401_RS12075	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LG401_RS12090	COG0124	histidyl-tRNA synthetase
LG401_RS12100	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG401_RS12100	COG3103	Sh3 type 3 domain protein
LG401_RS12100	COG4991	sh3 domain protein
LG401_RS12105	COG1490	D-aminoacyl-tRNA deacylase activity
LG401_RS12110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LG401_RS12115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LG401_RS12120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LG401_RS12120	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LG401_RS12125	COG5416	Lipopolysaccharide assembly protein A domain
LG401_RS12130	COG0490	domain, Protein
LG401_RS12135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG401_RS12135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LG401_RS12145	COG2244	polysaccharide biosynthetic process
LG401_RS12150	COG2323	membrane
LG401_RS12160	COG1862	Preprotein translocase
LG401_RS12165	COG0343	queuine tRNA-ribosyltransferase activity
LG401_RS12170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LG401_RS12180	COG2255	four-way junction helicase activity
LG401_RS12185	COG0632	four-way junction helicase activity
LG401_RS12195	COG2112	serine threonine protein kinase
LG401_RS12205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LG401_RS12220	COG1388	LysM domain
LG401_RS12220	COG1388	LysM domain
LG401_RS12225	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LG401_RS12230	COG0157	Belongs to the NadC ModD family
LG401_RS12235	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LG401_RS12240	COG1104	cysteine desulfurase activity
LG401_RS12245	COG1827	regulation of RNA biosynthetic process
LG401_RS12250	COG0077	Prephenate dehydratase
LG401_RS12255	COG4492	Belongs to the UPF0735 family
LG401_RS12260	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LG401_RS12265	COG3290	protein histidine kinase activity
LG401_RS12270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LG401_RS12275	COG2868	ribosomal protein
LG401_RS12280	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LG401_RS12285	COG1994	Peptidase M50
LG401_RS12290	COG0739	heme binding
LG401_RS12295	COG2894	cell division
LG401_RS12300	COG0850	regulation of cytokinetic process
LG401_RS12305	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LG401_RS12315	COG1077	Cell shape determining protein MreB Mrl
LG401_RS12320	COG2003	Belongs to the UPF0758 family
LG401_RS12325	COG0424	maF-like protein
LG401_RS12340	COG0285	dihydrofolate synthase activity
LG401_RS12345	COG0525	valine-tRNA ligase activity
LG401_RS12355	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG401_RS12360	COG1388	LysM domain
LG401_RS12365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LG401_RS12370	COG0113	porphobilinogen synthase activity
LG401_RS12375	COG1587	Uroporphyrinogen-III synthase
LG401_RS12380	COG0181	hydroxymethylbilane synthase activity
LG401_RS12385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LG401_RS12390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LG401_RS12400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LG401_RS12405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LG401_RS12410	COG0470	DNA polymerase III
LG401_RS12410	COG1067	ATP-dependent peptidase activity
LG401_RS12415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LG401_RS12420	COG0544	peptidyl-prolyl cis-trans isomerase activity
LG401_RS12425	COG0457	Tetratricopeptide repeat
LG401_RS12425	COG1477	protein flavinylation
LG401_RS12430	COG0066	3-isopropylmalate dehydratase activity
LG401_RS12435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LG401_RS12440	COG0473	3-isopropylmalate dehydrogenase activity
LG401_RS12445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LG401_RS12450	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LG401_RS12455	COG0440	acetolactate synthase activity
LG401_RS12460	COG0028	Belongs to the TPP enzyme family
LG401_RS12465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG401_RS12470	COG2706	6-phosphogluconolactonase activity
LG401_RS12475	COG3339	Conserved Protein
LG401_RS12480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LG401_RS12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LG401_RS12490	COG1696	Membrane protein involved in D-alanine export
LG401_RS12495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG401_RS12530	COG0622	Phosphoesterase
LG401_RS12535	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LG401_RS12540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LG401_RS12545	COG5401	PFAM Sporulation and spore germination
LG401_RS12550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LG401_RS12555	COG1846	Transcriptional regulator
LG401_RS12560	COG2197	response regulator
LG401_RS12565	COG2851	Citrate transporter
LG401_RS12570	COG0583	DNA-binding transcription factor activity
LG401_RS12575	COG2828	Protein conserved in bacteria
LG401_RS12585	COG0824	Thioesterase
LG401_RS12590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LG401_RS12595	COG1053	succinate dehydrogenase
LG401_RS12600	COG2009	succinate dehydrogenase
LG401_RS12605	COG1719	4-vinyl reductase, 4VR
LG401_RS12610	COG0527	aspartate kinase activity
LG401_RS12615	COG0322	excinuclease ABC activity
LG401_RS12620	COG3118	belongs to the thioredoxin family
LG401_RS12625	COG3534	alpha-L-arabinofuranosidase
LG401_RS12630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LG401_RS12635	COG2086	electron transfer activity
LG401_RS12640	COG1024	Enoyl-CoA hydratase
LG401_RS12645	COG1309	transcriptional regulator
LG401_RS12650	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS12660	COG3766	membrane
LG401_RS12665	COG1193	negative regulation of DNA recombination
LG401_RS12670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LG401_RS12670	COG1796	DNA polymerase
LG401_RS12675	COG1286	toxin biosynthetic process
LG401_RS12680	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LG401_RS12685	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LG401_RS12690	COG0072	phenylalanine-tRNA ligase activity
LG401_RS12690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG401_RS12695	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LG401_RS12700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LG401_RS12710	COG1966	Carbon starvation protein
LG401_RS12715	COG1363	Peptidase, m42
LG401_RS12725	COG3326	Membrane
LG401_RS12730	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LG401_RS12735	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LG401_RS12740	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LG401_RS12745	COG1346	cytolysis
LG401_RS12755	COG3279	Response regulator of the LytR AlgR family
LG401_RS12760	COG3275	phosphorelay sensor kinase activity
LG401_RS12765	COG1011	Hydrolase
LG401_RS12775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LG401_RS12785	COG0398	Pfam SNARE associated Golgi protein
LG401_RS12790	COG1484	DNA-dependent DNA replication
LG401_RS12795	COG3611	Membrane attachment protein
LG401_RS12800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LG401_RS12810	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LG401_RS12815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG401_RS12820	COG0237	dephospho-CoA kinase activity
LG401_RS12825	COG1971	Probably functions as a manganese efflux pump
LG401_RS12830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LG401_RS12835	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG401_RS12835	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LG401_RS12840	COG5002	protein histidine kinase activity
LG401_RS12845	COG0745	RESPONSE REGULATOR receiver
LG401_RS12850	COG0039	L-malate dehydrogenase activity
LG401_RS12855	COG0538	isocitrate dehydrogenase activity
LG401_RS12860	COG0372	Belongs to the citrate synthase family
LG401_RS12865	COG2707	UPF0756 membrane protein
LG401_RS12870	COG0628	permease
LG401_RS12875	COG3030	protein affecting phage T7 exclusion by the F plasmid
LG401_RS12885	COG0205	6-phosphofructokinase activity
LG401_RS12890	COG0825	malonyl-CoA metabolic process
LG401_RS12895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LG401_RS12900	COG0281	malic enzyme
LG401_RS12905	COG0587	DNA-directed DNA polymerase activity
LG401_RS12925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LG401_RS12935	COG4109	DRTGG domain
LG401_RS12940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LG401_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS12950	COG0165	Argininosuccinate lyase
LG401_RS12955	COG0137	argininosuccinate synthase activity
LG401_RS12960	COG0521	Mo-molybdopterin cofactor biosynthetic process
LG401_RS12965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LG401_RS12970	COG0827	DNA restriction-modification system
LG401_RS12975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LG401_RS12980	COG3874	Sporulation protein YtfJ
LG401_RS12990	COG1714	RDD family
LG401_RS12995	COG0616	signal peptide processing
LG401_RS13000	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LG401_RS13010	COG3239	Fatty acid desaturase
LG401_RS13015	COG4585	Histidine kinase
LG401_RS13020	COG2197	response regulator
LG401_RS13025	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS13030	COG0745	RESPONSE REGULATOR receiver
LG401_RS13035	COG2205	protein histidine kinase activity
LG401_RS13040	COG0772	Belongs to the SEDS family
LG401_RS13045	COG1695	Transcriptional regulator
LG401_RS13050	COG1136	(ABC) transporter
LG401_RS13055	COG0577	efflux transmembrane transporter activity
LG401_RS13060	COG0402	S-adenosylhomocysteine deaminase activity
LG401_RS13065	COG2249	NAD(P)H dehydrogenase (quinone) activity
LG401_RS13090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG401_RS13100	COG0301	tRNA thio-modification
LG401_RS13105	COG1104	cysteine desulfurase activity
LG401_RS13110	COG1114	Component of the transport system for branched-chain amino acids
LG401_RS13115	COG1114	Component of the transport system for branched-chain amino acids
LG401_RS13120	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LG401_RS13125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LG401_RS13130	COG1309	transcriptional regulator
LG401_RS13135	COG1956	GAF domain-containing protein
LG401_RS13140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LG401_RS13150	COG1335	isochorismatase
LG401_RS13160	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LG401_RS13165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LG401_RS13170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LG401_RS13175	COG0454	-acetyltransferase
LG401_RS13180	COG0517	IMP dehydrogenase activity
LG401_RS13185	COG0123	including yeast histone deacetylase and acetoin utilization protein
LG401_RS13190	COG1609	Transcriptional regulator
LG401_RS13195	COG1605	Chorismate mutase
LG401_RS13195	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LG401_RS13200	COG3118	belongs to the thioredoxin family
LG401_RS13205	COG4980	gas vesicle protein
LG401_RS13210	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LG401_RS13215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LG401_RS13220	COG1674	ftsk spoiiie
LG401_RS13225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LG401_RS13230	COG4848	Belongs to the UPF0354 family
LG401_RS13235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS13250	COG1363	Peptidase, m42
LG401_RS13255	COG5584	Small secreted protein
LG401_RS13260	COG0281	malic enzyme
LG401_RS13265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS13270	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LG401_RS13280	COG0510	thiamine kinase activity
LG401_RS13285	COG1597	lipid kinase activity
LG401_RS13295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LG401_RS13300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LG401_RS13305	COG3340	Belongs to the peptidase S51 family
LG401_RS13310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LG401_RS13315	COG2252	PERMEase
LG401_RS13320	COG1349	DNA-binding transcription factor activity
LG401_RS13325	COG1187	pseudouridine synthase activity
LG401_RS13330	COG2244	polysaccharide biosynthetic process
LG401_RS13335	COG2081	HI0933 family
LG401_RS13345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LG401_RS13350	COG3196	Protein conserved in bacteria
LG401_RS13360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LG401_RS13365	COG5578	integral membrane protein
LG401_RS13370	COG0673	inositol 2-dehydrogenase activity
LG401_RS13375	COG1653	transport
LG401_RS13380	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LG401_RS13385	COG4209	transmembrane transport
LG401_RS13390	COG2207	Transcriptional regulator
LG401_RS13395	COG1733	regulation of RNA biosynthetic process
LG401_RS13400	COG2814	Major facilitator Superfamily
LG401_RS13405	COG0656	L-ascorbic acid biosynthetic process
LG401_RS13410	COG1653	transport
LG401_RS13415	COG0395	ABC-type sugar transport system, permease component
LG401_RS13420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG401_RS13425	COG1073	alpha beta
LG401_RS13430	COG0495	leucyl-tRNA aminoacylation
LG401_RS13440	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS13440	COG2202	Pas domain
LG401_RS13445	COG2433	Pfam Transposase IS66
LG401_RS13450	COG0577	efflux transmembrane transporter activity
LG401_RS13455	COG1136	(ABC) transporter
LG401_RS13465	COG1131	(ABC) transporter
LG401_RS13470	COG1725	Transcriptional regulator
LG401_RS13485	COG1242	4 iron, 4 sulfur cluster binding
LG401_RS13490	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LG401_RS13500	COG2267	carboxylic ester hydrolase activity
LG401_RS13505	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LG401_RS13510	COG0367	asparagine synthase
LG401_RS13515	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LG401_RS13520	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LG401_RS13530	COG1506	peptidase
LG401_RS13535	COG1233	COG1233 Phytoene dehydrogenase and related
LG401_RS13555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LG401_RS13560	COG1116	anion transmembrane transporter activity
LG401_RS13565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LG401_RS13570	COG0494	nUDIX hydrolase
LG401_RS13575	COG2310	stress, protein
LG401_RS13590	COG4824	toxin secretion phage lysis holin
LG401_RS13600	COG0783	Belongs to the Dps family
LG401_RS13615	COG1854	S-ribosylhomocysteine lyase activity
LG401_RS13620	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LG401_RS13625	COG0288	reversible hydration of carbon dioxide
LG401_RS13630	COG0803	Belongs to the bacterial solute-binding protein 9 family
LG401_RS13630	COG3443	Belongs to the bacterial solute-binding protein 9 family
LG401_RS13635	COG0254	rRNA binding
LG401_RS13640	COG1271	oxidase subunit
LG401_RS13645	COG1294	oxidase, subunit
LG401_RS13660	COG4948	Mandelate Racemase Muconate Lactonizing
LG401_RS13665	COG0318	PFAM AMP-dependent synthetase and ligase
LG401_RS13670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LG401_RS13675	COG0596	Alpha beta hydrolase
LG401_RS13680	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LG401_RS13685	COG1169	isochorismate synthase
LG401_RS13690	COG1575	Belongs to the MenA family. Type 1 subfamily
LG401_RS13695	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LG401_RS13825	COG3859	Proton-coupled thiamine transporter YuaJ
LG401_RS13830	COG1247	-acetyltransferase
LG401_RS13835	COG3339	Conserved Protein
LG401_RS13840	COG0772	Belongs to the SEDS family
LG401_RS13845	COG0772	Belongs to the SEDS family
LG401_RS13850	COG2268	Band 7 protein
LG401_RS13855	COG1585	Membrane protein implicated in regulation of membrane protease activity
LG401_RS13860	COG2318	DinB family
LG401_RS13865	COG1454	alcohol dehydrogenase
LG401_RS13870	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS13875	COG1510	regulation of RNA biosynthetic process
LG401_RS13890	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS13890	COG5632	N-Acetylmuramoyl-L-alanine amidase
LG401_RS13950	COG3778	Protein conserved in bacteria
LG401_RS13955	COG3299	homolog of phage Mu protein gp47
LG401_RS13960	COG3628	GPW Gp25 family protein
LG401_RS13970	COG4193	domain, Protein
LG401_RS13975	COG1652	LysM domain
LG401_RS13980	COG3953	SLT domain
LG401_RS13980	COG5280	Phage tail tape measure protein TP901
LG401_RS13980	COG5280	Phage tail tape measure protein TP901
LG401_RS13980	COG3953	SLT domain
LG401_RS14035	COG4653	Phage capsid family
LG401_RS14040	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LG401_RS14045	COG5518	Phage portal protein
LG401_RS14050	COG1783	phage Terminase large subunit
LG401_RS14055	COG5484	DNA packaging
LG401_RS14060	COG1595	DNA-templated transcription, initiation
LG401_RS14070	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
LG401_RS14090	COG1396	sequence-specific DNA binding
LG401_RS14100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LG401_RS14115	COG0628	permease
LG401_RS14125	COG0673	inositol 2-dehydrogenase activity
LG401_RS14130	COG0693	protein deglycase activity
LG401_RS14135	COG0840	transmembrane signaling receptor activity
LG401_RS14140	COG0840	transmembrane signaling receptor activity
LG401_RS14145	COG0840	transmembrane signaling receptor activity
LG401_RS14150	COG0840	transmembrane signaling receptor activity
LG401_RS14165	COG2070	2-Nitropropane dioxygenase
LG401_RS14170	COG0432	Pfam Uncharacterised protein family UPF0047
LG401_RS14175	COG1253	flavin adenine dinucleotide binding
LG401_RS14180	COG2738	Putative neutral zinc metallopeptidase
LG401_RS14190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LG401_RS14205	COG0166	Belongs to the GPI family
LG401_RS14210	COG1979	alcohol dehydrogenase
LG401_RS14215	COG1979	alcohol dehydrogenase
LG401_RS14220	COG2155	Conserved Protein
LG401_RS14225	COG1098	S1 RNA binding domain
LG401_RS14230	COG0436	Aminotransferase
LG401_RS14235	COG1522	sequence-specific DNA binding
LG401_RS14240	COG2267	carboxylic ester hydrolase activity
LG401_RS14250	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LG401_RS14255	COG2205	protein histidine kinase activity
LG401_RS14270	COG5018	Exonuclease
LG401_RS14275	COG2814	Major facilitator Superfamily
LG401_RS14280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG401_RS14285	COG3011	Protein conserved in bacteria
LG401_RS14295	COG3290	protein histidine kinase activity
LG401_RS14300	COG4565	transcriptional regulatory protein
LG401_RS14305	COG1744	ABC transporter substrate-binding protein PnrA-like
LG401_RS14310	COG3845	ABC transporter
LG401_RS14315	COG4603	Belongs to the binding-protein-dependent transport system permease family
LG401_RS14320	COG1079	Belongs to the binding-protein-dependent transport system permease family
LG401_RS14325	COG3493	citrate carrier protein
LG401_RS14335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LG401_RS14335	COG2111	Na H antiporter
LG401_RS14340	COG2111	Na H antiporter
LG401_RS14345	COG1006	Multisubunit Na H antiporter MnhC subunit
LG401_RS14350	COG0651	ATP synthesis coupled electron transport
LG401_RS14355	COG1863	multisubunit Na H antiporter MnhE subunit
LG401_RS14360	COG2212	antiporter activity
LG401_RS14365	COG1320	monovalent cation:proton antiporter activity
LG401_RS14370	COG2050	protein possibly involved in aromatic compounds catabolism
LG401_RS14375	COG2197	response regulator
LG401_RS14390	COG0142	geranyltranstransferase activity
LG401_RS14405	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LG401_RS14410	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LG401_RS14415	COG1335	isochorismatase
LG401_RS14420	COG5506	Protein of unknown function (DUF1694)
LG401_RS14440	COG0628	permease
LG401_RS14455	COG1418	mRNA catabolic process
LG401_RS14460	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS14470	COG1511	domain protein
LG401_RS14475	COG0433	COG0433 Predicted ATPase
LG401_RS14475	COG1674	ftsk spoiiie
LG401_RS14480	COG4499	WXG100 protein secretion system (Wss), protein YukC
LG401_RS14485	COG5417	Belongs to the EsaB family
LG401_RS14490	COG4842	Belongs to the WXG100 family
LG401_RS14495	COG2508	Transcriptional regulator
LG401_RS14495	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LG401_RS14500	COG0686	Belongs to the AlaDH PNT family
LG401_RS14505	COG1268	BioY protein
LG401_RS14510	COG4326	sporulation control protein
LG401_RS14515	COG2056	Na+-H+ antiporter family
LG401_RS14520	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LG401_RS14525	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LG401_RS14530	COG3584	3D domain protein
LG401_RS14545	COG1252	NADH dehydrogenase
LG401_RS14550	COG0492	ferredoxin-NADP+ reductase activity
LG401_RS14565	COG0316	Belongs to the HesB IscA family
LG401_RS14570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LG401_RS14575	COG4844	belongs to the
LG401_RS14580	COG1252	NADH dehydrogenase
LG401_RS14590	COG4837	Protein of unknown function (DUF1462)
LG401_RS14600	COG1506	peptidase
LG401_RS14600	COG0823	Involved in the tonB-independent uptake of proteins
LG401_RS14600	COG4946	Tricorn protease homolog
LG401_RS14605	COG0083	homoserine kinase activity
LG401_RS14610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LG401_RS14615	COG0460	homoserine dehydrogenase
LG401_RS14620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG401_RS14625	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LG401_RS14630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LG401_RS14635	COG0647	UMP catabolic process
LG401_RS14640	COG2445	Protein of unknown function DUF86
LG401_RS14645	COG4470	Protein conserved in bacteria
LG401_RS14655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LG401_RS14660	COG0739	heme binding
LG401_RS14670	COG3377	Domain of unknown function (DUF1805)
LG401_RS14675	COG0737	Belongs to the 5'-nucleotidase family
LG401_RS14680	COG1801	Protein of unknown function DUF72
LG401_RS14685	COG2508	Transcriptional regulator
LG401_RS14695	COG2814	Major facilitator Superfamily
LG401_RS14700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LG401_RS14705	COG2356	endonuclease I
LG401_RS14715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS14720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS14725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS14740	COG5002	protein histidine kinase activity
LG401_RS14740	COG0642	Histidine kinase
LG401_RS14745	COG0745	RESPONSE REGULATOR receiver
LG401_RS14750	COG2311	Membrane
LG401_RS14760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LG401_RS14765	COG0719	Fe-S assembly protein
LG401_RS14770	COG0822	iron-sulfur transferase activity
LG401_RS14775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LG401_RS14780	COG0719	Fe-S assembly protein
LG401_RS14785	COG0396	ATPase activity
LG401_RS14795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LG401_RS14800	COG1464	Belongs to the NlpA lipoprotein family
LG401_RS14805	COG2011	ABC-type metal ion transport system permease component
LG401_RS14810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LG401_RS14820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LG401_RS14825	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LG401_RS14835	COG0509	glycine decarboxylation via glycine cleavage system
LG401_RS14840	COG1393	Belongs to the ArsC family
LG401_RS14845	COG1960	acyl-CoA dehydrogenase activity
LG401_RS14850	COG0183	Belongs to the thiolase family
LG401_RS14855	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG401_RS14855	COG1024	Enoyl-CoA hydratase
LG401_RS14870	COG5577	PFAM Coat F domain
LG401_RS14880	COG1120	ATPase activity
LG401_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS14895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG401_RS14900	COG0745	RESPONSE REGULATOR receiver
LG401_RS14905	COG2770	Histidine kinase
LG401_RS14905	COG2205	protein histidine kinase activity
LG401_RS14915	COG1309	transcriptional regulator
LG401_RS14920	COG0114	fumarate hydratase activity
LG401_RS14930	COG0697	spore germination
LG401_RS14935	COG0814	amino acid
LG401_RS14950	COG2197	response regulator
LG401_RS14955	COG4585	Histidine kinase
LG401_RS14960	COG4758	membrane
LG401_RS14970	COG1842	Phage shock protein A
LG401_RS14975	COG4758	membrane
LG401_RS14980	COG2096	Adenosyltransferase
LG401_RS14985	COG1120	ATPase activity
LG401_RS14990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS14995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS15005	COG2721	sulfolactate sulfo-lyase activity
LG401_RS15010	COG0246	Mannitol dehydrogenase
LG401_RS15015	COG1609	Transcriptional regulator
LG401_RS15020	COG1904	glucuronate isomerase
LG401_RS15025	COG2205	protein histidine kinase activity
LG401_RS15030	COG0745	RESPONSE REGULATOR receiver
LG401_RS15035	COG1120	ATPase activity
LG401_RS15040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS15045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS15050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS15055	COG0531	amino acid
LG401_RS15070	COG1988	membrane-bound metal-dependent
LG401_RS15075	COG1368	sulfuric ester hydrolase activity
LG401_RS15080	COG0725	ABC transporter, periplasmic molybdate-binding protein
LG401_RS15085	COG4149	molybdate abc transporter
LG401_RS15090	COG0656	L-ascorbic acid biosynthetic process
LG401_RS15095	COG1940	carbohydrate kinase activity
LG401_RS15100	COG0025	NhaP-type Na H and K H
LG401_RS15105	COG2860	membrane
LG401_RS15110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LG401_RS15115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LG401_RS15120	COG2217	Heavy metal translocating P-type atpase
LG401_RS15125	COG1121	(ABC) transporter
LG401_RS15130	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LG401_RS15135	COG0803	Belongs to the bacterial solute-binding protein 9 family
LG401_RS15145	COG3226	Transcriptional regulator
LG401_RS15150	COG0784	Response regulator, receiver
LG401_RS15155	COG4191	Histidine kinase
LG401_RS15160	COG1027	Aspartate ammonia-lyase
LG401_RS15170	COG2217	Heavy metal translocating P-type atpase
LG401_RS15175	COG2608	mercury ion transmembrane transporter activity
LG401_RS15180	COG1937	Protein conserved in bacteria
LG401_RS15195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LG401_RS15210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LG401_RS15215	COG0557	exoribonuclease II activity
LG401_RS15220	COG1647	Serine aminopeptidase, S33
LG401_RS15225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LG401_RS15230	COG2002	toxin-antitoxin pair type II binding
LG401_RS15235	COG1476	TRANSCRIPTIONal
LG401_RS15240	COG1396	sequence-specific DNA binding
LG401_RS15245	COG1396	sequence-specific DNA binding
LG401_RS15250	COG1733	regulation of RNA biosynthetic process
LG401_RS15255	COG1174	glycine betaine transport
LG401_RS15260	COG1732	Glycine betaine
LG401_RS15265	COG1174	glycine betaine transport
LG401_RS15270	COG0517	IMP dehydrogenase activity
LG401_RS15270	COG1125	glycine betaine transport
LG401_RS15275	COG1510	regulation of RNA biosynthetic process
LG401_RS15280	COG2095	MarC family integral membrane protein
LG401_RS15290	COG0456	acetyltransferase
LG401_RS15310	COG1131	(ABC) transporter
LG401_RS15320	COG0148	phosphopyruvate hydratase activity
LG401_RS15325	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LG401_RS15330	COG0149	triose-phosphate isomerase activity
LG401_RS15335	COG0126	phosphoglycerate kinase activity
LG401_RS15340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LG401_RS15345	COG2390	Transcriptional regulator
LG401_RS15350	COG0833	amino acid
LG401_RS15355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LG401_RS15360	COG3829	transcription factor binding
LG401_RS15365	COG2186	Transcriptional regulator
LG401_RS15370	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LG401_RS15380	COG0534	Mate efflux family protein
LG401_RS15385	COG4608	Belongs to the ABC transporter superfamily
LG401_RS15390	COG0444	Belongs to the ABC transporter superfamily
LG401_RS15395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LG401_RS15400	COG0601	transmembrane transport
LG401_RS15405	COG0747	negative chemotaxis
LG401_RS15410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG401_RS15415	COG0110	maltose O-acetyltransferase activity
LG401_RS15420	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LG401_RS15425	COG2244	polysaccharide biosynthetic process
LG401_RS15430	COG5039	Polysaccharide pyruvyl transferase
LG401_RS15435	COG1216	Glycosyl transferase, family 2
LG401_RS15445	COG0438	transferase activity, transferring glycosyl groups
LG401_RS15450	COG1215	transferase activity, transferring glycosyl groups
LG401_RS15455	COG0438	transferase activity, transferring glycosyl groups
LG401_RS15460	COG1086	Polysaccharide biosynthesis protein
LG401_RS15465	COG0489	protein tyrosine kinase activity
LG401_RS15470	COG3944	biosynthesis protein
LG401_RS15475	COG1396	sequence-specific DNA binding
LG401_RS15485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS15490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS15495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LG401_RS15500	COG0726	polysaccharide deacetylase
LG401_RS15505	COG0488	(ABC) transporter
LG401_RS15510	COG1124	(ABC) transporter
LG401_RS15525	COG0601	transmembrane transport
LG401_RS15530	COG0747	negative chemotaxis
LG401_RS15535	COG1819	glycosyl
LG401_RS15540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS15550	COG0740	serine-type endopeptidase activity
LG401_RS15555	COG1611	Belongs to the LOG family
LG401_RS15560	COG1694	Mazg nucleotide pyrophosphohydrolase
LG401_RS15565	COG0659	secondary active sulfate transmembrane transporter activity
LG401_RS15570	COG0288	reversible hydration of carbon dioxide
LG401_RS15575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LG401_RS15585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
LG401_RS15590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS15595	COG1481	regulation of sporulation
LG401_RS15600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LG401_RS15605	COG1660	Displays ATPase and GTPase activities
LG401_RS15610	COG1051	belongs to the nudix hydrolase family
LG401_RS15615	COG0492	ferredoxin-NADP+ reductase activity
LG401_RS15620	COG0791	NLP P60 protein
LG401_RS15620	COG3883	PFAM NLP P60 protein
LG401_RS15625	COG0457	Tetratricopeptide repeat
LG401_RS15630	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LG401_RS15630	COG0140	phosphoribosyl-ATP diphosphatase activity
LG401_RS15635	COG0107	imidazoleglycerol-phosphate synthase activity
LG401_RS15640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LG401_RS15645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LG401_RS15650	COG0131	Imidazoleglycerol-phosphate dehydratase
LG401_RS15655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LG401_RS15660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LG401_RS15665	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LG401_RS15670	COG4990	cell redox homeostasis
LG401_RS15675	COG2910	NAD(P)H-binding
LG401_RS15680	COG1959	2 iron, 2 sulfur cluster binding
LG401_RS15685	COG0110	maltose O-acetyltransferase activity
LG401_RS15690	COG0546	phosphoglycolate phosphatase activity
LG401_RS15695	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LG401_RS15705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LG401_RS15710	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LG401_RS15715	COG0363	glucosamine-6-phosphate deaminase activity
LG401_RS15720	COG2188	Transcriptional regulator
LG401_RS15725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LG401_RS15730	COG1950	PFAM Membrane protein of
LG401_RS15735	COG1983	PspC domain protein
LG401_RS15740	COG3595	metallopeptidase activity
LG401_RS15755	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LG401_RS15765	COG4897	Protein conserved in bacteria
LG401_RS15770	COG0574	Belongs to the PEP-utilizing enzyme family
LG401_RS15770	COG3848	Pyruvate phosphate dikinase
LG401_RS15775	COG1309	transcriptional regulator
LG401_RS15780	COG2814	Major facilitator Superfamily
LG401_RS15790	COG0745	RESPONSE REGULATOR receiver
LG401_RS15795	COG5002	protein histidine kinase activity
LG401_RS15800	COG1113	amino acid transport
LG401_RS15805	COG0778	Nitroreductase
LG401_RS15810	COG1733	regulation of RNA biosynthetic process
LG401_RS15815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG401_RS15825	COG0793	Belongs to the peptidase S41A family
LG401_RS15825	COG3409	Peptidoglycan-binding domain 1 protein
LG401_RS15830	COG0730	response to heat
LG401_RS15835	COG0791	NLP P60 protein
LG401_RS15835	COG3883	PFAM NLP P60 protein
LG401_RS15840	COG2177	Part of the ABC transporter FtsEX involved in
LG401_RS15845	COG2884	Cell division ATP-binding protein ftsE
LG401_RS15850	COG2010	Cytochrome c
LG401_RS15855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LG401_RS15875	COG0653	protein targeting
LG401_RS15880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LG401_RS15885	COG0840	transmembrane signaling receptor activity
LG401_RS15900	COG1516	flagellar protein fliS
LG401_RS15905	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LG401_RS15915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LG401_RS15920	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LG401_RS15930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LG401_RS15935	COG1256	bacterial-type flagellum assembly
LG401_RS15935	COG4786	Flagellar basal body rod
LG401_RS15940	COG3418	PFAM FlgN family protein
LG401_RS15955	COG1040	competence protein
LG401_RS15965	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LG401_RS15970	COG1307	EDD domain protein, DegV family
LG401_RS15975	COG2197	response regulator
LG401_RS15980	COG4585	Histidine kinase
LG401_RS15985	COG1739	Uncharacterized protein family UPF0029
LG401_RS15990	COG1316	TRANSCRIPTIONal
LG401_RS15995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LG401_RS16000	COG0438	transferase activity, transferring glycosyl groups
LG401_RS16005	COG1215	transferase activity, transferring glycosyl groups
LG401_RS16010	COG3206	protein involved in exopolysaccharide biosynthesis
LG401_RS16015	COG3307	-O-antigen
LG401_RS16020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LG401_RS16025	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LG401_RS16030	COG0297	glycogen (starch) synthase activity
LG401_RS16030	COG0438	transferase activity, transferring glycosyl groups
LG401_RS16035	COG2244	polysaccharide biosynthetic process
LG401_RS16050	COG2247	cell wall binding repeat
LG401_RS16050	COG0860	N-Acetylmuramoyl-L-alanine amidase
LG401_RS16055	COG2385	sporulation resulting in formation of a cellular spore
LG401_RS16055	COG2247	cell wall binding repeat
LG401_RS16065	COG1316	TRANSCRIPTIONal
LG401_RS16070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LG401_RS16075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LG401_RS16080	COG1134	teichoic acid transport
LG401_RS16085	COG1682	transport, permease protein
LG401_RS16095	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG401_RS16100	COG0438	transferase activity, transferring glycosyl groups
LG401_RS16105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LG401_RS16110	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LG401_RS16115	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG401_RS16120	COG4193	domain, Protein
LG401_RS16125	COG1482	cell wall glycoprotein biosynthetic process
LG401_RS16135	COG1175	transmembrane transport
LG401_RS16140	COG1653	transport
LG401_RS16145	COG2197	response regulator
LG401_RS16150	COG2972	Histidine kinase
LG401_RS16160	COG0454	-acetyltransferase
LG401_RS16165	COG0800	Aldolase
LG401_RS16170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG401_RS16175	COG1609	Transcriptional regulator
LG401_RS16180	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LG401_RS16185	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS16190	COG0697	spore germination
LG401_RS16195	COG0814	amino acid
LG401_RS16210	COG2814	Major facilitator Superfamily
LG401_RS16215	COG1316	TRANSCRIPTIONal
LG401_RS16220	COG0561	phosphatase activity
LG401_RS16225	COG0791	NLP P60 protein
LG401_RS16235	COG2843	Capsule synthesis protein
LG401_RS16245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LG401_RS16250	COG0697	spore germination
LG401_RS16265	COG1609	Transcriptional regulator
LG401_RS16270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LG401_RS16275	COG1869	D-ribose catabolic process
LG401_RS16280	COG1129	ABC transporter
LG401_RS16285	COG1172	Belongs to the binding-protein-dependent transport system permease family
LG401_RS16290	COG1879	ABC-type sugar transport system periplasmic component
LG401_RS16295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LG401_RS16300	COG0583	DNA-binding transcription factor activity
LG401_RS16305	COG0028	Belongs to the TPP enzyme family
LG401_RS16310	COG3527	Alpha-acetolactate decarboxylase
LG401_RS16315	COG1522	sequence-specific DNA binding
LG401_RS16320	COG2059	Chromate
LG401_RS16325	COG2059	Chromate
LG401_RS16330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LG401_RS16345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LG401_RS16350	COG2202	Pas domain
LG401_RS16350	COG1366	Belongs to the anti-sigma-factor antagonist family
LG401_RS16355	COG0561	phosphatase activity
LG401_RS16370	COG1970	mechanosensitive ion channel activity
LG401_RS16375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LG401_RS16380	COG0457	Tetratricopeptide repeat
LG401_RS16385	COG4786	Flagellar basal body rod
LG401_RS16390	COG4786	Flagellar basal body rod
LG401_RS16395	COG1077	Cell shape determining protein MreB Mrl
LG401_RS16400	COG1609	Transcriptional regulator
LG401_RS16405	COG1846	Transcriptional regulator
LG401_RS16410	COG2814	Major facilitator Superfamily
LG401_RS16415	COG0671	phosphoesterase, PA-phosphatase related
LG401_RS16420	COG0477	Major facilitator Superfamily
LG401_RS16425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS16430	COG0765	amino acid transport
LG401_RS16435	COG1126	abc transporter atp-binding protein
LG401_RS16440	COG0004	ammonium transporteR
LG401_RS16445	COG0347	Belongs to the P(II) protein family
LG401_RS16450	COG0739	heme binding
LG401_RS16455	COG1247	-acetyltransferase
LG401_RS16490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LG401_RS16495	COG0523	cobalamin synthesis protein
LG401_RS16500	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LG401_RS16505	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LG401_RS16510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LG401_RS16515	COG2223	nitrite transmembrane transporter activity
LG401_RS16520	COG0243	molybdopterin cofactor binding
LG401_RS16525	COG2304	oxidoreductase activity
LG401_RS16530	COG2304	oxidoreductase activity
LG401_RS16535	COG2385	sporulation resulting in formation of a cellular spore
LG401_RS16540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LG401_RS16550	COG4836	Membrane
LG401_RS16560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LG401_RS16565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LG401_RS16570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LG401_RS16575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LG401_RS16580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LG401_RS16585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LG401_RS16590	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LG401_RS16595	COG0356	it plays a direct role in the translocation of protons across the membrane
LG401_RS16605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LG401_RS16610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LG401_RS16615	COG4475	Protein of unknown function (DUF436)
LG401_RS16620	COG0698	ribose 5-phosphate isomerase
LG401_RS16625	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LG401_RS16630	COG1971	Probably functions as a manganese efflux pump
LG401_RS16635	COG0009	L-threonylcarbamoyladenylate synthase
LG401_RS16640	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LG401_RS16655	COG2890	protein-(glutamine-N5) methyltransferase activity
LG401_RS16660	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LG401_RS16665	COG0789	Transcriptional regulator
LG401_RS16670	COG0679	Auxin Efflux Carrier
LG401_RS16675	COG0281	malic enzyme
LG401_RS16680	COG1435	thymidine kinase activity
LG401_RS16685	COG0254	rRNA binding
LG401_RS16690	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LG401_RS16695	COG1494	fructose-1,6-bisphosphatase
LG401_RS16700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LG401_RS16705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LG401_RS16710	COG0191	fructose-bisphosphate aldolase activity
LG401_RS16715	COG2204	response regulator
LG401_RS16720	COG4821	SIS domain
LG401_RS16725	COG0504	CTP synthase activity
LG401_RS16730	COG3343	RNA polymerase activity
LG401_RS16740	COG1960	acyl-CoA dehydrogenase activity
LG401_RS16745	COG1960	acyl-CoA dehydrogenase activity
LG401_RS16750	COG1250	3-hydroxyacyl-CoA dehydrogenase
LG401_RS16755	COG0183	Belongs to the thiolase family
LG401_RS16760	COG0247	lactate metabolic process
LG401_RS16760	COG2181	nitrate reductase activity
LG401_RS16765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG401_RS16770	COG4294	response to UV
LG401_RS16780	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG401_RS16785	COG1132	(ABC) transporter
LG401_RS16790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LG401_RS16795	COG1619	proteins homologs of microcin C7 resistance protein MccF
LG401_RS16800	COG0018	arginyl-trna synthetase
LG401_RS16805	COG4506	Protein conserved in bacteria
LG401_RS16815	COG0010	Belongs to the arginase family
LG401_RS16820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LG401_RS16825	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LG401_RS16835	COG1994	Peptidase M50
LG401_RS16840	COG1942	4-Oxalocrotonate Tautomerase
LG401_RS16850	COG3465	dGTPase activity
LG401_RS16855	COG1078	dGTPase activity
LG401_RS16860	COG4844	belongs to the
LG401_RS16915	COG0280	phosphate acetyltransferase
LG401_RS16965	COG1396	sequence-specific DNA binding
LG401_RS16985	COG1073	alpha beta
LG401_RS16990	COG1522	sequence-specific DNA binding
LG401_RS16995	COG2814	Major facilitator Superfamily
LG401_RS17000	COG0077	Prephenate dehydratase
LG401_RS17005	COG1917	Cupin 2, conserved barrel domain protein
LG401_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS17015	COG0151	Belongs to the GarS family
LG401_RS17020	COG0436	Aminotransferase
LG401_RS17025	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS17030	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
LG401_RS17035	COG1091	dTDP-4-dehydrorhamnose reductase activity
LG401_RS17040	COG1088	dTDP-glucose 4,6-dehydratase activity
LG401_RS17045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LG401_RS17050	COG3980	spore coat polysaccharide biosynthesis protein
LG401_RS17055	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LG401_RS17060	COG2089	acid synthase
LG401_RS17065	COG0456	acetyltransferase
LG401_RS17070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LG401_RS17075	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LG401_RS17080	COG0463	Glycosyl transferase, family 2
LG401_RS17100	COG2363	Small membrane protein
LG401_RS17105	COG2233	PERMEase
LG401_RS17115	COG1012	belongs to the aldehyde dehydrogenase family
LG401_RS17120	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LG401_RS17125	COG1216	Glycosyl transferase, family 2
LG401_RS17135	COG0351	phosphomethylpyrimidine kinase
LG401_RS17155	COG1621	beta-fructofuranosidase activity
LG401_RS17160	COG1263	PTS System
LG401_RS17160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS17165	COG3711	transcriptional antiterminator
LG401_RS17175	COG1404	Belongs to the peptidase S8 family
LG401_RS17180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LG401_RS17185	COG0778	Nitroreductase
LG401_RS17190	COG0772	Belongs to the SEDS family
LG401_RS17200	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LG401_RS17205	COG1845	cytochrome c oxidase, subunit III
LG401_RS17210	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LG401_RS17215	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LG401_RS17225	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LG401_RS17230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LG401_RS17235	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LG401_RS17250	COG2246	polysaccharide biosynthetic process
LG401_RS17270	COG3162	membrane
LG401_RS17275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LG401_RS17285	COG0352	thiamine-phosphate diphosphorylase activity
LG401_RS17290	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LG401_RS17295	COG0583	DNA-binding transcription factor activity
LG401_RS17305	COG1346	cytolysis
LG401_RS17310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LG401_RS17315	COG0346	lactoylglutathione lyase activity
LG401_RS17325	COG0765	amino acid transport
LG401_RS17330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LG401_RS17335	COG0457	Tetratricopeptide repeat
LG401_RS17345	COG2357	RelA SpoT domain protein
LG401_RS17350	COG1172	Belongs to the binding-protein-dependent transport system permease family
LG401_RS17355	COG1129	ABC transporter
LG401_RS17365	COG3420	alginic acid biosynthetic process
LG401_RS17370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LG401_RS17380	COG1486	melibiose metabolic process
LG401_RS17385	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG401_RS17390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS17395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS17400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS17400	COG3711	transcriptional antiterminator
LG401_RS17420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LG401_RS17435	COG1595	DNA-templated transcription, initiation
LG401_RS17445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LG401_RS17450	COG4988	ABC transporter
LG401_RS17455	COG1294	oxidase, subunit
LG401_RS17460	COG1271	oxidase subunit
LG401_RS17485	COG4509	Sortase family
LG401_RS17510	COG5386	Cell surface protein
LG401_RS17515	COG5386	Cell surface protein
LG401_RS17520	COG1733	regulation of RNA biosynthetic process
LG401_RS17525	COG2514	catechol 2,3-dioxygenase activity
LG401_RS17530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG401_RS17530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LG401_RS17535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG401_RS17535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LG401_RS17540	COG0346	lactoylglutathione lyase activity
LG401_RS17545	COG0726	polysaccharide deacetylase
LG401_RS17550	COG1447	Phosphotransferase system cellobiose-specific component IIA
LG401_RS17555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS17560	COG2723	6-phospho-beta-galactosidase activity
LG401_RS17565	COG1312	Catalyzes the dehydration of D-mannonate
LG401_RS17575	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LG401_RS17580	COG3711	transcriptional antiterminator
LG401_RS17580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LG401_RS17605	COG1757	Na H antiporter
LG401_RS17610	COG1027	Aspartate ammonia-lyase
LG401_RS17615	COG0252	asparaginase activity
LG401_RS17620	COG1396	sequence-specific DNA binding
LG401_RS17645	COG4842	Belongs to the WXG100 family
LG401_RS17650	COG2195	Cleaves the N-terminal amino acid of tripeptides
LG401_RS17665	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LG401_RS17670	COG2723	6-phospho-beta-galactosidase activity
LG401_RS17675	COG1263	PTS System
LG401_RS17675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS17675	COG2190	(PTS) system
LG401_RS17680	COG3711	transcriptional antiterminator
LG401_RS17685	COG3878	Protein conserved in bacteria
LG401_RS17695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG401_RS17700	COG1122	ATPase activity
LG401_RS17705	COG4721	ABC-type cobalt transport system, permease component
LG401_RS17710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LG401_RS17745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LG401_RS17750	COG0778	Nitroreductase
LG401_RS17755	COG1846	Transcriptional regulator
LG401_RS17760	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LG401_RS17765	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LG401_RS17770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LG401_RS17775	COG2390	Transcriptional regulator
LG401_RS17785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LG401_RS17785	COG2755	lipolytic protein G-D-S-L family
LG401_RS17805	COG0561	phosphatase activity
LG401_RS17810	COG0789	Transcriptional regulator
LG401_RS17815	COG0673	inositol 2-dehydrogenase activity
LG401_RS17820	COG0840	transmembrane signaling receptor activity
LG401_RS17825	COG1113	amino acid transport
LG401_RS17830	COG4335	DNA alkylation repair
LG401_RS17840	COG1070	Carbohydrate kinase
LG401_RS17845	COG1737	Transcriptional regulator
LG401_RS17860	COG0583	DNA-binding transcription factor activity
LG401_RS17865	COG1609	Transcriptional regulator
LG401_RS17870	COG2182	Extracellular solute-binding protein
LG401_RS17875	COG1175	transmembrane transport
LG401_RS17880	COG3833	ABC-type maltose transport systems, permease component
LG401_RS17890	COG1874	Beta-galactosidase
LG401_RS17895	COG2851	Citrate transporter
LG401_RS17905	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LG401_RS17910	COG1131	(ABC) transporter
LG401_RS17920	COG1131	(ABC) transporter
LG401_RS17945	COG2824	Alkylphosphonate utilization operon protein PhnA
LG401_RS17950	COG1929	Belongs to the glycerate kinase type-1 family
LG401_RS17955	COG2610	gluconate transmembrane transporter activity
LG401_RS17960	COG3835	regulator
LG401_RS17965	COG1309	transcriptional regulator
LG401_RS17970	COG2814	Major facilitator Superfamily
LG401_RS17980	COG1136	(ABC) transporter
LG401_RS17990	COG0457	Tetratricopeptide repeat
LG401_RS17995	COG3711	transcriptional antiterminator
LG401_RS18000	COG2723	6-phospho-beta-galactosidase activity
LG401_RS18005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LG401_RS18005	COG2190	(PTS) system
LG401_RS18005	COG1263	PTS System
LG401_RS18040	COG1113	amino acid transport
LG401_RS18045	COG1609	Transcriptional regulator
LG401_RS18050	COG2814	Major facilitator Superfamily
LG401_RS18055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LG401_RS18060	COG2814	Major facilitator Superfamily
LG401_RS18080	COG5444	nuclease activity
LG401_RS18095	COG2723	6-phospho-beta-galactosidase activity
LG401_RS18105	COG2188	Transcriptional regulator
LG401_RS18135	COG1131	(ABC) transporter
LG401_RS18140	COG3620	sequence-specific DNA binding
LG401_RS18155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LG401_RS18160	COG2814	Major facilitator Superfamily
LG401_RS18165	COG0640	Transcriptional regulator
LG401_RS18170	COG0038	chloride channel
LG401_RS18175	COG2323	membrane
LG401_RS18220	COG1438	arginine binding
LG401_RS18230	COG2003	Belongs to the UPF0758 family
LG401_RS18260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LG401_RS18270	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LG401_RS18280	COG4720	Psort location CytoplasmicMembrane, score
LG401_RS18300	COG0456	acetyltransferase
LG401_RS18305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LG401_RS18310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LG401_RS18315	COG4853	Protein conserved in bacteria
LG401_RS18320	COG4863	YycH protein
LG401_RS18325	COG5002	protein histidine kinase activity
LG401_RS18330	COG0745	RESPONSE REGULATOR receiver
LG401_RS18355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LG401_RS18365	COG2311	Membrane
LG401_RS18370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LG401_RS18375	COG1309	transcriptional regulator
LG401_RS18380	COG2124	cytochrome p450
LG401_RS18385	COG0346	lactoylglutathione lyase activity
LG401_RS18390	COG0305	Participates in initiation and elongation during chromosome replication
LG401_RS18405	COG2819	hydrolase of the alpha beta superfamily
LG401_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
LG401_RS18415	COG1169	isochorismate synthase
LG401_RS18420	COG1021	2,3-dihydroxybenzoate-AMP ligase
LG401_RS18425	COG1535	isochorismatase
LG401_RS18425	COG3433	isochorismatase activity
LG401_RS18430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LG401_RS18435	COG3251	PFAM MbtH domain protein
LG401_RS18440	COG2207	Transcriptional regulator
LG401_RS18440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS18445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LG401_RS18450	COG2819	hydrolase of the alpha beta superfamily
LG401_RS18455	COG3093	addiction module antidote protein HigA
LG401_RS18460	COG2807	transmembrane transport
LG401_RS18465	COG0359	binds to the 23S rRNA
LG401_RS18470	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LG401_RS18475	COG4241	membrane
LG401_RS18480	COG1227	inorganic diphosphatase activity
LG401_RS18490	COG1595	DNA-templated transcription, initiation
LG401_RS18500	COG0753	catalase activity
LG401_RS18505	COG0655	NAD(P)H dehydrogenase (quinone) activity
LG401_RS18510	COG0400	carboxylic ester hydrolase activity
LG401_RS18515	COG0346	lactoylglutathione lyase activity
LG401_RS18520	COG1174	glycine betaine transport
LG401_RS18525	COG0517	IMP dehydrogenase activity
LG401_RS18525	COG1125	glycine betaine transport
LG401_RS18530	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LG401_RS18535	COG0629	single-stranded DNA binding
LG401_RS18540	COG0360	Binds together with S18 to 16S ribosomal RNA
LG401_RS18545	COG0012	GTP binding
LG401_RS18550	COG4481	Protein conserved in bacteria
LG401_RS18565	COG3949	Membrane
LG401_RS18575	COG1475	DNA binding
LG401_RS18580	COG1192	Involved in chromosome partitioning
LG401_RS18590	COG1475	DNA binding
LG401_RS18595	COG0357	Ribosomal RNA small subunit methyltransferase G
LG401_RS18600	COG0445	tRNA wobble uridine modification
LG401_RS18605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LG401_RS18610	COG1847	R3H domain protein
LG401_RS18615	COG0706	membrane insertase activity
LG401_RS18620	COG0594	ribonuclease P activity
LG401_RS18625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LG401_RS18630	COG0840	transmembrane signaling receptor activity
LG401_RS18635	COG1331	Highly conserved protein containing a thioredoxin domain