locus-tag	class	description
BPUM_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BPUM_RS00010	COG0592	DNA-directed DNA polymerase activity
BPUM_RS00015	COG2501	S4 domain
BPUM_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BPUM_RS00030	COG0187	DNA topoisomerase II activity
BPUM_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPUM_RS00070	COG0516	GMP reductase activity
BPUM_RS00070	COG0517	IMP dehydrogenase activity
BPUM_RS00075	COG1686	Belongs to the peptidase S11 family
BPUM_RS00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BPUM_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BPUM_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BPUM_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BPUM_RS00100	COG0840	transmembrane signaling receptor activity
BPUM_RS00110	COG1428	Deoxynucleoside kinase
BPUM_RS00115	COG1428	Deoxynucleoside kinase
BPUM_RS00120	COG3858	chitin binding
BPUM_RS00120	COG1388	LysM domain
BPUM_RS00125	COG1335	isochorismatase
BPUM_RS00130	COG0590	tRNA wobble adenosine to inosine editing
BPUM_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BPUM_RS00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BPUM_RS00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BPUM_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BPUM_RS00200	COG3853	Toxic anion resistance protein (TelA)
BPUM_RS00205	COG1982	Orn Lys Arg decarboxylase major
BPUM_RS00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BPUM_RS00215	COG3870	Protein conserved in bacteria
BPUM_RS00220	COG1728	Protein conserved in bacteria
BPUM_RS00225	COG0470	DNA polymerase III
BPUM_RS00230	COG1774	PSP1 C-terminal conserved region
BPUM_RS00235	COG4467	Involved in initiation control of chromosome replication
BPUM_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BPUM_RS00245	COG2827	Endonuclease containing a URI domain
BPUM_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BPUM_RS00255	COG2002	toxin-antitoxin pair type II binding
BPUM_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPUM_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPUM_RS00265	COG0084	hydrolase, TatD family'
BPUM_RS00270	COG3584	3D domain protein
BPUM_RS00270	COG3583	domain protein
BPUM_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BPUM_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BPUM_RS00290	COG4466	Protein conserved in bacteria
BPUM_RS00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BPUM_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BPUM_RS00310	COG0251	oxidation-reduction process
BPUM_RS00315	COG2088	sporulation resulting in formation of a cellular spore
BPUM_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BPUM_RS00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BPUM_RS00335	COG0193	aminoacyl-tRNA hydrolase activity
BPUM_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BPUM_RS00350	COG2002	toxin-antitoxin pair type II binding
BPUM_RS00355	COG2244	polysaccharide biosynthetic process
BPUM_RS00360	COG3956	TIGRFAM MazG family protein
BPUM_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BPUM_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BPUM_RS00385	COG1098	S1 RNA binding domain
BPUM_RS00400	COG2208	phosphoserine phosphatase activity
BPUM_RS00405	COG2304	oxidoreductase activity
BPUM_RS00410	COG0515	serine threonine protein kinase
BPUM_RS00415	COG0037	tRNA processing
BPUM_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BPUM_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BPUM_RS00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BPUM_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BPUM_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BPUM_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BPUM_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BPUM_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
BPUM_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BPUM_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BPUM_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BPUM_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BPUM_RS00480	COG1396	sequence-specific DNA binding
BPUM_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BPUM_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BPUM_RS00515	COG4463	regulation of RNA biosynthetic process
BPUM_RS00520	COG3880	PFAM UvrB UvrC protein
BPUM_RS00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BPUM_RS00530	COG0542	response to heat
BPUM_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BPUM_RS00540	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BPUM_RS00545	COG4956	integral membrane protein (PIN domain superfamily)
BPUM_RS00550	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BPUM_RS00555	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BPUM_RS00560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BPUM_RS00565	COG1045	serine acetyltransferase
BPUM_RS00570	COG0215	cysteine-tRNA ligase activity
BPUM_RS00575	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BPUM_RS00580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPUM_RS00585	COG3688	RNA-binding protein containing a PIN domain
BPUM_RS00590	COG1595	DNA-templated transcription, initiation
BPUM_RS00595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BPUM_RS00600	COG0250	Participates in transcription elongation, termination and antitermination
BPUM_RS00610	COG0081	regulation of translation
BPUM_RS00615	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BPUM_RS00620	COG0222	ribosome binding
BPUM_RS00625	COG2813	Specifically methylates the guanine in position
BPUM_RS00630	COG0085	RNA polymerase activity
BPUM_RS00635	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BPUM_RS00640	COG1358	cellular component organization or biogenesis
BPUM_RS00645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BPUM_RS00650	COG0049	tRNA binding
BPUM_RS00655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BPUM_RS00660	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BPUM_RS00665	COG0596	Alpha beta hydrolase
BPUM_RS00675	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BPUM_RS00680	COG0088	Forms part of the polypeptide exit tunnel
BPUM_RS00685	COG0089	rRNA binding
BPUM_RS00690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BPUM_RS00695	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BPUM_RS00700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BPUM_RS00705	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BPUM_RS00715	COG0255	Belongs to the universal ribosomal protein uL29 family
BPUM_RS00720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BPUM_RS00725	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BPUM_RS00730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BPUM_RS00735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BPUM_RS00740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPUM_RS00745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BPUM_RS00750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BPUM_RS00755	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BPUM_RS00760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BPUM_RS00765	COG1841	ribosomal large subunit assembly
BPUM_RS00770	COG0200	Binds to the 23S rRNA
BPUM_RS00775	COG0201	protein transport
BPUM_RS00780	COG0563	adenylate kinase activity
BPUM_RS00785	COG0024	Methionine aminopeptidase
BPUM_RS00790	COG2163	COG2163 Ribosomal protein L14E L6E L27E
BPUM_RS00795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BPUM_RS00800	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BPUM_RS00805	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BPUM_RS00810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BPUM_RS00815	COG0202	RNA polymerase activity
BPUM_RS00820	COG0203	ribosomal protein L17
BPUM_RS00825	COG1122	ATPase activity
BPUM_RS00830	COG1122	ATPase activity
BPUM_RS00835	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPUM_RS00840	COG0101	tRNA pseudouridine synthase activity
BPUM_RS00845	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BPUM_RS00850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BPUM_RS00855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS00885	COG0860	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS00890	COG0489	protein tyrosine kinase activity
BPUM_RS00900	COG2194	sulfuric ester hydrolase activity
BPUM_RS00905	COG0726	polysaccharide deacetylase
BPUM_RS00935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS00940	COG0659	secondary active sulfate transmembrane transporter activity
BPUM_RS00945	COG0385	Bile acid
BPUM_RS00950	COG3876	Protein conserved in bacteria
BPUM_RS00955	COG1472	Belongs to the glycosyl hydrolase 3 family
BPUM_RS00960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BPUM_RS00965	COG1263	PTS System
BPUM_RS00965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS00970	COG1737	Transcriptional regulator
BPUM_RS00975	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BPUM_RS01010	COG1595	DNA-templated transcription, initiation
BPUM_RS01015	COG5662	AntiSigma factor
BPUM_RS01020	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BPUM_RS01025	COG4856	YbbR-like protein
BPUM_RS01030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BPUM_RS01040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BPUM_RS01060	COG1131	(ABC) transporter
BPUM_RS01080	COG2311	Membrane
BPUM_RS01100	COG1476	TRANSCRIPTIONal
BPUM_RS01115	COG1113	amino acid transport
BPUM_RS01120	COG0584	glycerophosphoryl diester phosphodiesterase
BPUM_RS01125	COG2271	Major facilitator Superfamily
BPUM_RS01135	COG1331	Highly conserved protein containing a thioredoxin domain
BPUM_RS01150	COG1937	Protein conserved in bacteria
BPUM_RS01155	COG2210	Belongs to the sulfur carrier protein TusA family
BPUM_RS01160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPUM_RS01165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPUM_RS01165	COG0425	Belongs to the sulfur carrier protein TusA family
BPUM_RS01170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BPUM_RS01170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPUM_RS01175	COG0425	Belongs to the sulfur carrier protein TusA family
BPUM_RS01180	COG0730	response to heat
BPUM_RS01185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BPUM_RS01190	COG2814	Major facilitator Superfamily
BPUM_RS01200	COG1846	Transcriptional regulator
BPUM_RS01210	COG1683	Conserved Protein
BPUM_RS01220	COG0656	L-ascorbic acid biosynthetic process
BPUM_RS01225	COG0371	Dehydrogenase
BPUM_RS01230	COG1054	Belongs to the UPF0176 family
BPUM_RS01235	COG0531	amino acid
BPUM_RS01245	COG3711	transcriptional antiterminator
BPUM_RS01250	COG2190	(PTS) system
BPUM_RS01250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS01250	COG1263	PTS System
BPUM_RS01255	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS01275	COG3711	transcriptional antiterminator
BPUM_RS01275	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS01280	COG1940	carbohydrate kinase activity
BPUM_RS01285	COG0383	alpha-mannosidase activity
BPUM_RS01290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS01295	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS01305	COG1404	Belongs to the peptidase S8 family
BPUM_RS01320	COG0833	amino acid
BPUM_RS01325	COG2040	homocysteine
BPUM_RS01335	COG1695	Transcriptional regulator
BPUM_RS01345	COG2814	Major facilitator Superfamily
BPUM_RS01350	COG0456	acetyltransferase
BPUM_RS01365	COG1404	Belongs to the peptidase S8 family
BPUM_RS01375	COG1309	transcriptional regulator
BPUM_RS01380	COG1917	Cupin 2, conserved barrel domain protein
BPUM_RS01385	COG1063	alcohol dehydrogenase
BPUM_RS01390	COG1846	Transcriptional regulator
BPUM_RS01395	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS01400	COG0531	amino acid
BPUM_RS01410	COG0596	Alpha beta hydrolase
BPUM_RS01415	COG1115	amino acid carrier protein
BPUM_RS01420	COG2066	Belongs to the glutaminase family
BPUM_RS01425	COG4191	Histidine kinase
BPUM_RS01430	COG0784	Response regulator, receiver
BPUM_RS01435	COG1405	negative regulation of cell septum assembly
BPUM_RS01435	COG3012	SEC-C Motif Domain Protein
BPUM_RS01445	COG0667	Aldo Keto reductase
BPUM_RS01450	COG3290	protein histidine kinase activity
BPUM_RS01455	COG3279	Response regulator of the LytR AlgR family
BPUM_RS01460	COG4555	ABC transporter
BPUM_RS01465	COG1668	transmembrane transport
BPUM_RS01480	COG3773	Cell wall hydrolase
BPUM_RS01485	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS01495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BPUM_RS01500	COG2310	stress, protein
BPUM_RS01505	COG2310	stress, protein
BPUM_RS01510	COG2310	stress, protein
BPUM_RS01515	COG0861	Integral membrane protein TerC family
BPUM_RS01545	COG3853	Toxic anion resistance protein (TelA)
BPUM_RS01550	COG0517	IMP dehydrogenase activity
BPUM_RS01550	COG4175	Glycine betaine
BPUM_RS01555	COG4176	ABC-type proline glycine betaine transport system permease component
BPUM_RS01560	COG2113	Glycine betaine
BPUM_RS01575	COG1473	amidohydrolase
BPUM_RS01580	COG1288	antiporter activity
BPUM_RS01585	COG0039	L-malate dehydrogenase activity
BPUM_RS01590	COG1620	l-lactate permease
BPUM_RS01595	COG1609	Transcriptional regulator
BPUM_RS01600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BPUM_RS01605	COG0561	phosphatase activity
BPUM_RS01610	COG0673	inositol 2-dehydrogenase activity
BPUM_RS01615	COG0738	Major facilitator superfamily
BPUM_RS01620	COG1280	lysine exporter protein (LysE YggA)
BPUM_RS01630	COG3403	YqcI/YcgG family
BPUM_RS01635	COG1113	amino acid transport
BPUM_RS01640	COG3665	Urea carboxylase-associated protein
BPUM_RS01645	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BPUM_RS01650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BPUM_RS01655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BPUM_RS01665	COG0477	Major facilitator Superfamily
BPUM_RS01675	COG0583	DNA-binding transcription factor activity
BPUM_RS01680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BPUM_RS01685	COG3458	cephalosporin-C deacetylase activity
BPUM_RS01695	COG3541	Predicted nucleotidyltransferase
BPUM_RS01700	COG0506	proline dehydrogenase activity
BPUM_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS01710	COG2508	Transcriptional regulator
BPUM_RS01715	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BPUM_RS01720	COG0765	amino acid transport
BPUM_RS01725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS01735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BPUM_RS01740	COG1522	sequence-specific DNA binding
BPUM_RS01745	COG2746	aminoglycoside 3-N-acetyltransferase activity
BPUM_RS01755	COG0840	transmembrane signaling receptor activity
BPUM_RS01755	COG3290	protein histidine kinase activity
BPUM_RS01760	COG3209	COG3209 Rhs family protein
BPUM_RS01785	COG3842	ATPase activity
BPUM_RS01790	COG1176	ABC-type spermidine putrescine transport system, permease component I
BPUM_RS01800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BPUM_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BPUM_RS01810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BPUM_RS01825	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
BPUM_RS01830	COG0697	spore germination
BPUM_RS01835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BPUM_RS01850	COG2364	Membrane
BPUM_RS01860	COG3764	Sortase (surface protein transpeptidase)
BPUM_RS01865	COG2002	toxin-antitoxin pair type II binding
BPUM_RS01885	COG1136	(ABC) transporter
BPUM_RS01890	COG1126	abc transporter atp-binding protein
BPUM_RS01895	COG0765	amino acid transport
BPUM_RS01900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS01905	COG0412	Dienelactone hydrolase
BPUM_RS01915	COG3104	oligopeptide transport
BPUM_RS01920	COG5434	Belongs to the glycosyl hydrolase 28 family
BPUM_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BPUM_RS01930	COG0456	acetyltransferase
BPUM_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS01940	COG0765	amino acid transport
BPUM_RS01945	COG1126	abc transporter atp-binding protein
BPUM_RS01950	COG1473	amidohydrolase
BPUM_RS01955	COG2079	MmgE PrpD family protein
BPUM_RS01965	COG0745	RESPONSE REGULATOR receiver
BPUM_RS01970	COG5002	protein histidine kinase activity
BPUM_RS01970	COG3850	Histidine kinase
BPUM_RS01975	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS01980	COG0527	aspartate kinase activity
BPUM_RS01985	COG2814	Major facilitator Superfamily
BPUM_RS01990	COG1309	transcriptional regulator
BPUM_RS02000	COG0640	Transcriptional regulator
BPUM_RS02005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BPUM_RS02010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BPUM_RS02015	COG0531	amino acid
BPUM_RS02020	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS02025	COG2249	NAD(P)H dehydrogenase (quinone) activity
BPUM_RS02030	COG4549	nuclear export factor GLE1
BPUM_RS02035	COG1276	copper resistance
BPUM_RS02035	COG2372	response to copper ion
BPUM_RS02040	COG2213	PTS system mannitol-specific
BPUM_RS02045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS02050	COG0246	Mannitol dehydrogenase
BPUM_RS02055	COG0840	transmembrane signaling receptor activity
BPUM_RS02075	COG0346	lactoylglutathione lyase activity
BPUM_RS02085	COG0561	phosphatase activity
BPUM_RS02090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BPUM_RS02095	COG1914	H( )-stimulated, divalent metal cation uptake system
BPUM_RS02100	COG4336	lyase activity
BPUM_RS02105	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BPUM_RS02110	COG1984	allophanate hydrolase subunit 2
BPUM_RS02115	COG1414	Transcriptional regulator
BPUM_RS02120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BPUM_RS02125	COG2755	lipolytic protein G-D-S-L family
BPUM_RS02135	COG3711	transcriptional antiterminator
BPUM_RS02140	COG2226	methyltransferase
BPUM_RS02145	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS02150	COG3871	stress protein (general stress protein 26)
BPUM_RS02170	COG2814	Major facilitator Superfamily
BPUM_RS02175	COG1802	Transcriptional regulator
BPUM_RS02180	COG0697	spore germination
BPUM_RS02185	COG0473	3-isopropylmalate dehydrogenase activity
BPUM_RS02190	COG0551	DNA topoisomerase type I activity
BPUM_RS02190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BPUM_RS02195	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BPUM_RS02200	COG3706	GGDEF domain
BPUM_RS02205	COG5298	Protein conserved in bacteria
BPUM_RS02210	COG1215	transferase activity, transferring glycosyl groups
BPUM_RS02220	COG0531	amino acid
BPUM_RS02225	COG0028	Belongs to the TPP enzyme family
BPUM_RS02230	COG5444	nuclease activity
BPUM_RS02250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS02255	COG1914	H( )-stimulated, divalent metal cation uptake system
BPUM_RS02260	COG2261	transglycosylase associated protein
BPUM_RS02265	COG2217	Heavy metal translocating P-type atpase
BPUM_RS02270	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BPUM_RS02275	COG3290	protein histidine kinase activity
BPUM_RS02280	COG4565	transcriptional regulatory protein
BPUM_RS02285	COG1301	dicarboxylic acid transport
BPUM_RS02290	COG0628	permease
BPUM_RS02295	COG1301	dicarboxylic acid transport
BPUM_RS02300	COG1131	(ABC) transporter
BPUM_RS02305	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BPUM_RS02315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS02320	COG1181	Belongs to the D-alanine--D-alanine ligase family
BPUM_RS02325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BPUM_RS02340	COG0513	Belongs to the DEAD box helicase family
BPUM_RS02345	COG3402	PFAM membrane-flanked domain
BPUM_RS02350	COG3428	Bacterial PH domain
BPUM_RS02355	COG0705	Rhomboid family
BPUM_RS02360	COG0736	holo-[acyl-carrier-protein] synthase activity
BPUM_RS02365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BPUM_RS02370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BPUM_RS02375	COG0864	Transcriptional regulator
BPUM_RS02380	COG2337	Toxic component of a toxin-antitoxin (TA) module
BPUM_RS02385	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS02390	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS02395	COG2172	sigma factor antagonist activity
BPUM_RS02400	COG2208	phosphoserine phosphatase activity
BPUM_RS02405	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS02410	COG2172	sigma factor antagonist activity
BPUM_RS02415	COG1191	sigma factor activity
BPUM_RS02420	COG2208	phosphoserine phosphatase activity
BPUM_RS02425	COG2183	response to ionizing radiation
BPUM_RS02430	COG3091	SprT-like family
BPUM_RS02435	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BPUM_RS02440	COG0022	dehydrogenase e1 component
BPUM_RS02445	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS02450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BPUM_RS02455	COG3284	Transcriptional regulator
BPUM_RS02500	COG0456	acetyltransferase
BPUM_RS02500	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BPUM_RS02505	COG1278	Cold shock
BPUM_RS02510	COG1329	Transcriptional regulator
BPUM_RS02515	COG1064	alcohol dehydrogenase
BPUM_RS02520	COG0789	Transcriptional regulator
BPUM_RS02535	COG0477	Major facilitator Superfamily
BPUM_RS02540	COG0657	acetylesterase activity
BPUM_RS02560	COG0252	asparaginase activity
BPUM_RS02580	COG2814	Major facilitator Superfamily
BPUM_RS02625	COG1309	transcriptional regulator
BPUM_RS02630	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BPUM_RS02635	COG1846	Transcriptional regulator
BPUM_RS02640	COG0778	Nitroreductase
BPUM_RS02655	COG1396	sequence-specific DNA binding
BPUM_RS02665	COG0456	acetyltransferase
BPUM_RS02670	COG0583	DNA-binding transcription factor activity
BPUM_RS02675	COG0667	Aldo Keto reductase
BPUM_RS02685	COG4122	O-methyltransferase activity
BPUM_RS02695	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BPUM_RS02700	COG0697	spore germination
BPUM_RS02705	COG1301	dicarboxylic acid transport
BPUM_RS02745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BPUM_RS02750	COG0802	atpase or kinase
BPUM_RS02755	COG1214	PFAM Peptidase M22, glycoprotease
BPUM_RS02760	COG0456	acetyltransferase
BPUM_RS02765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BPUM_RS02770	COG0488	(ABC) transporter
BPUM_RS02775	COG0315	cyclic pyranopterin monophosphate synthase activity
BPUM_RS02780	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BPUM_RS02785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BPUM_RS02790	COG0805	protein transport
BPUM_RS02795	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BPUM_RS02805	COG1266	CAAX protease self-immunity
BPUM_RS02810	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BPUM_RS02815	COG0459	protein refolding
BPUM_RS02835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BPUM_RS02840	COG0823	Involved in the tonB-independent uptake of proteins
BPUM_RS02850	COG2132	Multicopper oxidase
BPUM_RS02855	COG1113	amino acid transport
BPUM_RS02860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BPUM_RS02865	COG0714	Associated with various cellular activities
BPUM_RS02870	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BPUM_RS02875	COG1305	Transglutaminase-like
BPUM_RS02880	COG0519	Catalyzes the synthesis of GMP from XMP
BPUM_RS02880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BPUM_RS02915	COG1674	ftsk spoiiie
BPUM_RS02920	COG2946	Replication initiation factor
BPUM_RS03010	COG0433	COG0433 Predicted ATPase
BPUM_RS03015	COG5644	endopeptidase inhibitor activity
BPUM_RS03020	COG0791	NLP P60 protein
BPUM_RS03020	COG0741	lytic transglycosylase activity
BPUM_RS03050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BPUM_RS03055	COG2207	Transcriptional regulator
BPUM_RS03060	COG2207	Transcriptional regulator
BPUM_RS03065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS03080	COG1595	DNA-templated transcription, initiation
BPUM_RS03090	COG2814	Major facilitator Superfamily
BPUM_RS03095	COG0583	DNA-binding transcription factor activity
BPUM_RS03100	COG2252	PERMEase
BPUM_RS03105	COG3064	Membrane
BPUM_RS03110	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
BPUM_RS03120	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BPUM_RS03125	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BPUM_RS03130	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BPUM_RS03135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BPUM_RS03140	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPUM_RS03145	COG0047	phosphoribosylformylglycinamidine synthase activity
BPUM_RS03150	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BPUM_RS03155	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BPUM_RS03160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BPUM_RS03165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BPUM_RS03170	COG0138	bifunctional purine biosynthesis protein purh
BPUM_RS03175	COG0151	Belongs to the GarS family
BPUM_RS03200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BPUM_RS03205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BPUM_RS03210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BPUM_RS03215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BPUM_RS03225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BPUM_RS03230	COG4496	protein, YerC YecD
BPUM_RS03235	COG0069	glutamate synthase activity
BPUM_RS03250	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BPUM_RS03255	COG0210	DNA helicase
BPUM_RS03260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BPUM_RS03265	COG4851	CamS sex pheromone cAM373 precursor
BPUM_RS03295	COG1250	3-hydroxyacyl-CoA dehydrogenase
BPUM_RS03310	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS03330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPUM_RS03330	COG4221	oxidoreductase activity
BPUM_RS03330	COG0300	oxidoreductase activity
BPUM_RS03330	COG3321	synthase
BPUM_RS03340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BPUM_RS03345	COG1785	Belongs to the alkaline phosphatase family
BPUM_RS03350	COG1285	pathogenesis
BPUM_RS03355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BPUM_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPUM_RS03365	COG0154	amidase activity
BPUM_RS03370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BPUM_RS03375	COG1309	transcriptional regulator
BPUM_RS03380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BPUM_RS03385	COG1957	nucleoside hydrolase
BPUM_RS03390	COG1597	lipid kinase activity
BPUM_RS03395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPUM_RS03400	COG0326	Molecular chaperone. Has ATPase activity
BPUM_RS03425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BPUM_RS03435	COG1737	Transcriptional regulator
BPUM_RS03440	COG1263	PTS System
BPUM_RS03440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS03455	COG1959	2 iron, 2 sulfur cluster binding
BPUM_RS03460	COG0492	ferredoxin-NADP+ reductase activity
BPUM_RS03475	COG1486	melibiose metabolic process
BPUM_RS03510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BPUM_RS03515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BPUM_RS03520	COG1442	glycosyl transferase family 8
BPUM_RS03525	COG1216	Glycosyl transferase, family 2
BPUM_RS03530	COG1442	glycosyl transferase family 8
BPUM_RS03535	COG2223	nitrite transmembrane transporter activity
BPUM_RS03545	COG0471	metal ion transport
BPUM_RS03560	COG0071	Belongs to the small heat shock protein (HSP20) family
BPUM_RS03575	COG0531	amino acid
BPUM_RS03580	COG0457	Tetratricopeptide repeat
BPUM_RS03580	COG0463	Glycosyl transferase, family 2
BPUM_RS03585	COG0488	(ABC) transporter
BPUM_RS03590	COG0789	Transcriptional regulator
BPUM_RS03595	COG2814	Major facilitator Superfamily
BPUM_RS03600	COG0488	(ABC) transporter
BPUM_RS03605	COG0513	Belongs to the DEAD box helicase family
BPUM_RS03610	COG2130	NADP-dependent
BPUM_RS03630	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPUM_RS03630	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPUM_RS03635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BPUM_RS03645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BPUM_RS03645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BPUM_RS03655	COG3290	protein histidine kinase activity
BPUM_RS03660	COG4565	transcriptional regulatory protein
BPUM_RS03665	COG3181	Tripartite tricarboxylate transporter family receptor
BPUM_RS03670	COG2851	Citrate transporter
BPUM_RS03680	COG3479	Phenolic acid decarboxylase
BPUM_RS03685	COG1695	Transcriptional regulator
BPUM_RS03690	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BPUM_RS03695	COG1254	Belongs to the acylphosphatase family
BPUM_RS03700	COG2258	MOSC domain
BPUM_RS03705	COG0024	Methionine aminopeptidase
BPUM_RS03710	COG1263	PTS System
BPUM_RS03710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS03715	COG3739	integral membrane protein
BPUM_RS03730	COG1368	sulfuric ester hydrolase activity
BPUM_RS03735	COG0076	glutamate decarboxylase activity
BPUM_RS03750	COG1263	PTS System
BPUM_RS03750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS03755	COG0366	Alpha amylase catalytic
BPUM_RS03760	COG2188	Transcriptional regulator
BPUM_RS03770	COG0737	Belongs to the 5'-nucleotidase family
BPUM_RS03775	COG0693	protein deglycase activity
BPUM_RS03780	COG4840	Belongs to the UPF0435 family
BPUM_RS03785	COG1115	amino acid carrier protein
BPUM_RS03790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPUM_RS03795	COG4980	gas vesicle protein
BPUM_RS03800	COG1295	ribonuclease BN
BPUM_RS03805	COG0477	Major facilitator Superfamily
BPUM_RS03815	COG0387	Pfam Sodium calcium exchanger
BPUM_RS03825	COG0217	transcriptional regulatory protein
BPUM_RS03835	COG0668	transmembrane transport
BPUM_RS03840	COG0535	radical SAM domain protein
BPUM_RS03850	COG0726	polysaccharide deacetylase
BPUM_RS03860	COG0598	Magnesium transport protein CorA
BPUM_RS03870	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BPUM_RS03875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BPUM_RS03880	COG1309	transcriptional regulator
BPUM_RS03885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPUM_RS03885	COG3320	Male sterility
BPUM_RS03900	COG0789	Transcriptional regulator
BPUM_RS03905	COG2814	Major facilitator Superfamily
BPUM_RS03915	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BPUM_RS03955	COG2076	Multidrug Resistance protein
BPUM_RS03960	COG2076	Multidrug Resistance protein
BPUM_RS03965	COG1309	transcriptional regulator
BPUM_RS03975	COG4637	Psort location Cytoplasmic, score
BPUM_RS03980	COG2755	lipolytic protein G-D-S-L family
BPUM_RS03985	COG0492	ferredoxin-NADP+ reductase activity
BPUM_RS03995	COG1595	DNA-templated transcription, initiation
BPUM_RS04015	COG2318	DinB family
BPUM_RS04025	COG1846	Transcriptional regulator
BPUM_RS04030	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BPUM_RS04030	COG0392	lysyltransferase activity
BPUM_RS04050	COG0778	Nitroreductase
BPUM_RS04060	COG1090	epimerase
BPUM_RS04065	COG2137	regulation of response to DNA damage stimulus
BPUM_RS04085	COG0463	Glycosyl transferase, family 2
BPUM_RS04090	COG4485	Bacterial membrane protein, YfhO
BPUM_RS04110	COG2140	Oxalate decarboxylase
BPUM_RS04115	COG1191	sigma factor activity
BPUM_RS04125	COG1988	membrane-bound metal-dependent
BPUM_RS04130	COG1194	a g-specific adenine glycosylase
BPUM_RS04140	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS04160	COG3557	Belongs to the UPF0374 family
BPUM_RS04165	COG1132	(ABC) transporter
BPUM_RS04170	COG0444	Belongs to the ABC transporter superfamily
BPUM_RS04175	COG4608	Belongs to the ABC transporter superfamily
BPUM_RS04180	COG0747	negative chemotaxis
BPUM_RS04185	COG0601	transmembrane transport
BPUM_RS04190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BPUM_RS04195	COG4129	membrane
BPUM_RS04200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BPUM_RS04205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BPUM_RS04210	COG0735	belongs to the Fur family
BPUM_RS04365	COG1368	sulfuric ester hydrolase activity
BPUM_RS04370	COG0681	Belongs to the peptidase S26 family
BPUM_RS04380	COG2873	o-acetylhomoserine
BPUM_RS04390	COG1131	(ABC) transporter
BPUM_RS04420	COG3382	B3 4 domain protein
BPUM_RS04425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BPUM_RS04435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BPUM_RS04450	COG2766	serine protein kinase
BPUM_RS04455	COG2718	Belongs to the UPF0229 family
BPUM_RS04460	COG1566	PFAM secretion protein HlyD family protein
BPUM_RS04465	COG2814	Major facilitator Superfamily
BPUM_RS04470	COG0655	NAD(P)H dehydrogenase (quinone) activity
BPUM_RS04480	COG1278	Cold shock
BPUM_RS04485	COG3706	GGDEF domain
BPUM_RS04510	COG5577	PFAM Coat F domain
BPUM_RS04515	COG5002	protein histidine kinase activity
BPUM_RS04520	COG4085	toxin activity
BPUM_RS04520	COG0737	Belongs to the 5'-nucleotidase family
BPUM_RS04520	COG1525	nuclease
BPUM_RS04525	COG3764	Sortase (surface protein transpeptidase)
BPUM_RS04530	COG0564	pseudouridine synthase activity
BPUM_RS04540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BPUM_RS04545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BPUM_RS04545	COG3153	acetyltransferase
BPUM_RS04560	COG3835	regulator
BPUM_RS04565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BPUM_RS04570	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BPUM_RS04575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BPUM_RS04580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BPUM_RS04585	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BPUM_RS04590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BPUM_RS04595	COG2203	Gaf domain
BPUM_RS04595	COG4585	Histidine kinase
BPUM_RS04600	COG2197	response regulator
BPUM_RS04620	COG0753	catalase activity
BPUM_RS04625	COG1959	2 iron, 2 sulfur cluster binding
BPUM_RS04630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BPUM_RS04630	COG1017	nitric oxide dioxygenase activity
BPUM_RS04635	COG2719	SpoVR family
BPUM_RS04640	COG1785	Belongs to the alkaline phosphatase family
BPUM_RS04645	COG0791	NLP P60 protein
BPUM_RS04645	COG1388	LysM domain
BPUM_RS04655	COG2801	Transposase and inactivated derivatives
BPUM_RS04670	COG1595	DNA-templated transcription, initiation
BPUM_RS04675	COG0204	Acyl-transferase
BPUM_RS04680	COG1253	flavin adenine dinucleotide binding
BPUM_RS04685	COG0789	Transcriptional regulator
BPUM_RS04690	COG1253	flavin adenine dinucleotide binding
BPUM_RS04705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BPUM_RS04710	COG0584	glycerophosphoryl diester phosphodiesterase
BPUM_RS04720	COG0668	transmembrane transport
BPUM_RS04725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BPUM_RS04730	COG0726	polysaccharide deacetylase
BPUM_RS04735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BPUM_RS04740	COG0589	response to stress
BPUM_RS04745	COG1132	(ABC) transporter
BPUM_RS04750	COG1132	(ABC) transporter
BPUM_RS04755	COG0702	epimerase
BPUM_RS04765	COG3842	ATPase activity
BPUM_RS04770	COG2508	Transcriptional regulator
BPUM_RS04780	COG0189	ligase activity
BPUM_RS04785	COG0189	ligase activity
BPUM_RS04790	COG4399	Belongs to the UPF0754 family
BPUM_RS04795	COG3679	Belongs to the UPF0342 family
BPUM_RS04800	COG0561	phosphatase activity
BPUM_RS04805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BPUM_RS04815	COG1024	Enoyl-CoA hydratase
BPUM_RS04825	COG0420	3'-5' exonuclease activity
BPUM_RS04830	COG4717	serine-type aminopeptidase activity
BPUM_RS04835	COG3481	metal-dependent phosphohydrolase, HD sub domain
BPUM_RS04845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BPUM_RS04865	COG1846	Transcriptional regulator
BPUM_RS04870	COG4980	gas vesicle protein
BPUM_RS04885	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BPUM_RS04890	COG0537	adenosine 5'-monophosphoramidase activity
BPUM_RS04895	COG1131	(ABC) transporter
BPUM_RS04900	COG4473	ABC transporter
BPUM_RS04910	COG1473	amidohydrolase
BPUM_RS04920	COG2329	Antibiotic biosynthesis monooxygenase
BPUM_RS04925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BPUM_RS04930	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BPUM_RS04935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BPUM_RS04940	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BPUM_RS04945	COG1309	transcriptional regulator
BPUM_RS04950	COG1511	domain protein
BPUM_RS04955	COG1363	Peptidase, m42
BPUM_RS04960	COG1301	dicarboxylic acid transport
BPUM_RS04965	COG1234	tRNA 3'-trailer cleavage
BPUM_RS04970	COG0095	Lipoate-protein ligase
BPUM_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS04985	COG0501	Belongs to the peptidase M48B family
BPUM_RS04990	COG1404	Belongs to the peptidase S8 family
BPUM_RS04995	COG0406	alpha-ribazole phosphatase activity
BPUM_RS05000	COG0840	transmembrane signaling receptor activity
BPUM_RS05005	COG0723	plastoquinol--plastocyanin reductase activity
BPUM_RS05005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BPUM_RS05010	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS05020	COG4903	ComK protein
BPUM_RS05035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BPUM_RS05040	COG2814	Major facilitator Superfamily
BPUM_RS05045	COG2732	(Barnase) inhibitor
BPUM_RS05050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS05055	COG4605	iron ion homeostasis
BPUM_RS05060	COG4604	ABC transporter, ATP-binding protein
BPUM_RS05065	COG4607	ABC-type enterochelin transport system periplasmic component
BPUM_RS05070	COG1316	TRANSCRIPTIONal
BPUM_RS05080	COG0398	Pfam SNARE associated Golgi protein
BPUM_RS05085	COG0681	Belongs to the peptidase S26 family
BPUM_RS05090	COG3180	Ammonia monooxygenase
BPUM_RS05100	COG0501	Belongs to the peptidase M48B family
BPUM_RS05105	COG2259	Doxx family
BPUM_RS05110	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BPUM_RS05115	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BPUM_RS05120	COG1074	ATP-dependent DNA helicase activity
BPUM_RS05125	COG0420	3'-5' exonuclease activity
BPUM_RS05130	COG0419	ATPase involved in DNA repair
BPUM_RS05135	COG1403	HNH endonuclease
BPUM_RS05175	COG5337	Spore coat protein CotH
BPUM_RS05185	COG0179	Fumarylacetoacetate (FAA) hydrolase
BPUM_RS05200	COG0367	asparagine synthase
BPUM_RS05215	COG1562	ergosterol biosynthetic process
BPUM_RS05220	COG0534	Mate efflux family protein
BPUM_RS05225	COG2207	Transcriptional regulator
BPUM_RS05225	COG1917	Cupin 2, conserved barrel domain protein
BPUM_RS05255	COG0076	glutamate decarboxylase activity
BPUM_RS05285	COG0646	methionine synthase
BPUM_RS05285	COG1410	methionine synthase
BPUM_RS05290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BPUM_RS05290	COG0646	methionine synthase
BPUM_RS05295	COG1666	GTP binding
BPUM_RS05300	COG2996	Protein conserved in bacteria
BPUM_RS05305	COG1744	ABC transporter substrate-binding protein PnrA-like
BPUM_RS05310	COG0840	transmembrane signaling receptor activity
BPUM_RS05315	COG1307	EDD domain protein, DegV family
BPUM_RS05320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BPUM_RS05340	COG0561	phosphatase activity
BPUM_RS05345	COG1073	alpha beta
BPUM_RS05350	COG2151	metal-sulfur cluster biosynthetic enzyme
BPUM_RS05355	COG0277	FAD linked oxidase domain protein
BPUM_RS05360	COG2271	Major facilitator Superfamily
BPUM_RS05365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BPUM_RS05370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BPUM_RS05375	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BPUM_RS05380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BPUM_RS05385	COG0505	Belongs to the CarA family
BPUM_RS05390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BPUM_RS05395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BPUM_RS05405	COG2814	Major facilitator Superfamily
BPUM_RS05415	COG2267	carboxylic ester hydrolase activity
BPUM_RS05425	COG1744	ABC transporter substrate-binding protein PnrA-like
BPUM_RS05440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BPUM_RS05445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BPUM_RS05450	COG5504	Zn-dependent protease
BPUM_RS05455	COG0444	Belongs to the ABC transporter superfamily
BPUM_RS05460	COG4608	Belongs to the ABC transporter superfamily
BPUM_RS05470	COG0601	transmembrane transport
BPUM_RS05475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BPUM_RS05495	COG0180	Tryptophanyl-tRNA synthetase
BPUM_RS05500	COG4166	transmembrane transport
BPUM_RS05505	COG0601	transmembrane transport
BPUM_RS05510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BPUM_RS05515	COG0444	Belongs to the ABC transporter superfamily
BPUM_RS05520	COG4608	Belongs to the ABC transporter superfamily
BPUM_RS05530	COG0456	acetyltransferase
BPUM_RS05535	COG1393	Belongs to the ArsC family
BPUM_RS05540	COG0861	Integral membrane protein TerC family
BPUM_RS05545	COG4862	establishment of competence for transformation
BPUM_RS05550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPUM_RS05560	COG1164	Oligoendopeptidase f
BPUM_RS05565	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BPUM_RS05570	COG2346	COG2346, Truncated hemoglobins
BPUM_RS05575	COG0741	lytic transglycosylase activity
BPUM_RS05580	COG4116	CYTH
BPUM_RS05590	COG2357	RelA SpoT domain protein
BPUM_RS05595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BPUM_RS05600	COG0564	pseudouridine synthase activity
BPUM_RS05605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BPUM_RS05610	COG0475	glutathione-regulated potassium exporter activity
BPUM_RS05610	COG0569	domain protein
BPUM_RS05615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BPUM_RS05620	COG0352	thiamine-phosphate diphosphorylase activity
BPUM_RS05630	COG2104	thiamine diphosphate biosynthetic process
BPUM_RS05635	COG2022	thiamine diphosphate biosynthetic process
BPUM_RS05640	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BPUM_RS05645	COG0351	phosphomethylpyrimidine kinase
BPUM_RS05650	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BPUM_RS05705	COG0210	DNA helicase
BPUM_RS05715	COG2153	protein acetylation
BPUM_RS05720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BPUM_RS05725	COG2382	esterase
BPUM_RS05730	COG0626	cystathionine gamma-synthase activity
BPUM_RS05735	COG0626	cystathionine gamma-synthase activity
BPUM_RS05750	COG1733	regulation of RNA biosynthetic process
BPUM_RS05760	COG0825	malonyl-CoA metabolic process
BPUM_RS05795	COG0457	Tetratricopeptide repeat
BPUM_RS05810	COG0583	DNA-binding transcription factor activity
BPUM_RS05825	COG0583	DNA-binding transcription factor activity
BPUM_RS05830	COG2807	transmembrane transport
BPUM_RS05840	COG0457	Tetratricopeptide repeat
BPUM_RS05860	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BPUM_RS05875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS05880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS05885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS05890	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS05910	COG4195	phage-related replication protein
BPUM_RS05915	COG2856	Zn peptidase
BPUM_RS05920	COG3409	Peptidoglycan-binding domain 1 protein
BPUM_RS05920	COG5632	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS05935	COG0306	phosphate transporter
BPUM_RS05940	COG1392	Phosphate transport regulator
BPUM_RS05950	COG0405	Gamma-glutamyltransferase
BPUM_RS05965	COG3775	system Galactitol-specific IIC component
BPUM_RS05980	COG1063	alcohol dehydrogenase
BPUM_RS05985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BPUM_RS05990	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS05990	COG0022	dehydrogenase e1 component
BPUM_RS05995	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS06000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BPUM_RS06005	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS06010	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS06015	COG2390	Transcriptional regulator
BPUM_RS06025	COG0531	amino acid
BPUM_RS06030	COG0346	lactoylglutathione lyase activity
BPUM_RS06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BPUM_RS06040	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BPUM_RS06045	COG2362	D-Aminopeptidase
BPUM_RS06050	COG0601	transmembrane transport
BPUM_RS06055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BPUM_RS06060	COG0444	Belongs to the ABC transporter superfamily
BPUM_RS06065	COG4166	transmembrane transport
BPUM_RS06070	COG1619	proteins homologs of microcin C7 resistance protein MccF
BPUM_RS06075	COG4948	Mandelate Racemase Muconate Lactonizing
BPUM_RS06080	COG0791	NLP P60 protein
BPUM_RS06085	COG4608	Belongs to the ABC transporter superfamily
BPUM_RS06090	COG1834	amidinotransferase
BPUM_RS06095	COG1607	acyl-coa hydrolase
BPUM_RS06100	COG1695	Transcriptional regulator
BPUM_RS06115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS06125	COG2076	Multidrug Resistance protein
BPUM_RS06130	COG2076	Multidrug Resistance protein
BPUM_RS06140	COG0788	formyltetrahydrofolate deformylase activity
BPUM_RS06150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BPUM_RS06155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BPUM_RS06160	COG0457	Tetratricopeptide repeat
BPUM_RS06170	COG1764	response to oxidative stress
BPUM_RS06175	COG1846	Transcriptional regulator
BPUM_RS06180	COG1764	response to oxidative stress
BPUM_RS06185	COG0590	tRNA wobble adenosine to inosine editing
BPUM_RS06190	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BPUM_RS06195	COG1404	Belongs to the peptidase S8 family
BPUM_RS06200	COG0745	RESPONSE REGULATOR receiver
BPUM_RS06205	COG3850	Histidine kinase
BPUM_RS06205	COG5002	protein histidine kinase activity
BPUM_RS06210	COG3212	peptidase
BPUM_RS06215	COG3212	peptidase
BPUM_RS06220	COG2239	Acts as a magnesium transporter
BPUM_RS06230	COG0583	DNA-binding transcription factor activity
BPUM_RS06245	COG0789	Transcriptional regulator
BPUM_RS06255	COG1846	Transcriptional regulator
BPUM_RS06260	COG5001	Diguanylate cyclase
BPUM_RS06260	COG3300	MHYT domain
BPUM_RS06265	COG0586	Pfam SNARE associated Golgi protein
BPUM_RS06270	COG0861	Integral membrane protein TerC family
BPUM_RS06275	COG1191	sigma factor activity
BPUM_RS06295	COG0501	Belongs to the peptidase M48B family
BPUM_RS06300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BPUM_RS06305	COG2323	membrane
BPUM_RS06310	COG3594	Acyltransferase
BPUM_RS06315	COG5002	protein histidine kinase activity
BPUM_RS06320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BPUM_RS06325	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BPUM_RS06330	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BPUM_RS06335	COG0436	Aminotransferase
BPUM_RS06340	COG1850	ribulose-bisphosphate carboxylase activity
BPUM_RS06345	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BPUM_RS06350	COG0235	Class ii aldolase
BPUM_RS06355	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BPUM_RS06365	COG3852	Histidine kinase
BPUM_RS06370	COG1846	Transcriptional regulator
BPUM_RS06375	COG1360	Flagellar Motor Protein
BPUM_RS06380	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BPUM_RS06385	COG0542	response to heat
BPUM_RS06390	COG3949	Membrane
BPUM_RS06395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BPUM_RS06400	COG0720	synthase
BPUM_RS06405	COG0602	queuosine metabolic process
BPUM_RS06410	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BPUM_RS06425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS06430	COG4873	Protein conserved in bacteria
BPUM_RS06440	COG3773	Cell wall hydrolase
BPUM_RS06445	COG2244	polysaccharide biosynthetic process
BPUM_RS06450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS06455	COG2217	Heavy metal translocating P-type atpase
BPUM_RS06460	COG0006	proline dipeptidase activity
BPUM_RS06465	COG1609	Transcriptional regulator
BPUM_RS06470	COG3711	transcriptional antiterminator
BPUM_RS06475	COG2190	(PTS) system
BPUM_RS06475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS06475	COG1263	PTS System
BPUM_RS06480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS06485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BPUM_RS06495	COG1533	DNA photolyase activity
BPUM_RS06500	COG0840	transmembrane signaling receptor activity
BPUM_RS06510	COG2084	Dehydrogenase
BPUM_RS06520	COG2340	Cysteine-rich secretory protein family
BPUM_RS06525	COG0768	penicillin binding
BPUM_RS06530	COG4191	Histidine kinase
BPUM_RS06535	COG0436	Aminotransferase
BPUM_RS06540	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BPUM_RS06545	COG1714	RDD family
BPUM_RS06555	COG0835	chemotaxis
BPUM_RS06555	COG0784	Response regulator, receiver
BPUM_RS06570	COG2814	Major facilitator Superfamily
BPUM_RS06575	COG1376	ErfK ybiS ycfS ynhG family protein
BPUM_RS06580	COG1408	metallophosphoesterase
BPUM_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS06590	COG2200	EAL domain
BPUM_RS06595	COG3546	catalase activity
BPUM_RS06600	COG4703	Protein of unknown function (DUF1797)
BPUM_RS06605	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BPUM_RS06615	COG0517	IMP dehydrogenase activity
BPUM_RS06620	COG0583	DNA-binding transcription factor activity
BPUM_RS06630	COG0716	FMN binding
BPUM_RS06640	COG0716	FMN binding
BPUM_RS06645	COG2171	N-acyltransferase activity
BPUM_RS06650	COG1473	amidohydrolase
BPUM_RS06660	COG0668	transmembrane transport
BPUM_RS06665	COG0450	alkyl hydroperoxide reductase
BPUM_RS06670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS06685	COG0746	molybdenum cofactor guanylyltransferase activity
BPUM_RS06690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BPUM_RS06695	COG0303	'Molybdopterin
BPUM_RS06700	COG1763	Mo-molybdopterin cofactor biosynthetic process
BPUM_RS06705	COG0314	molybdopterin synthase activity
BPUM_RS06710	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BPUM_RS06725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BPUM_RS06730	COG1136	(ABC) transporter
BPUM_RS06735	COG0577	efflux transmembrane transporter activity
BPUM_RS06740	COG1349	DNA-binding transcription factor activity
BPUM_RS06745	COG1105	Belongs to the carbohydrate kinase PfkB family
BPUM_RS06750	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS06750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS06750	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS06765	COG0488	(ABC) transporter
BPUM_RS06770	COG2309	aminopeptidase activity
BPUM_RS06775	COG1077	Cell shape determining protein MreB Mrl
BPUM_RS06780	COG2002	toxin-antitoxin pair type II binding
BPUM_RS06785	COG3852	Histidine kinase
BPUM_RS06790	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BPUM_RS06790	COG2105	PFAM AIG2 family protein
BPUM_RS06795	COG0569	domain protein
BPUM_RS06800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BPUM_RS06805	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPUM_RS06810	COG5503	Protein of unknown function (DUF1447)
BPUM_RS06815	COG0561	phosphatase activity
BPUM_RS06820	COG0242	peptide deformylase activity
BPUM_RS06835	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BPUM_RS06840	COG0022	dehydrogenase e1 component
BPUM_RS06845	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS06850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BPUM_RS06855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS06865	COG1982	Orn Lys Arg decarboxylase major
BPUM_RS06870	COG4476	Belongs to the UPF0223 family
BPUM_RS06880	COG4493	Belongs to the UPF0637 family
BPUM_RS06890	COG0483	inositol monophosphate 1-phosphatase activity
BPUM_RS06905	COG1217	gtp-binding protein TYPA
BPUM_RS06915	COG4896	Protein conserved in bacteria
BPUM_RS06925	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BPUM_RS06930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BPUM_RS06935	COG2066	Belongs to the glutaminase family
BPUM_RS06940	COG4838	Belongs to the UPF0358 family
BPUM_RS06945	COG0772	Belongs to the SEDS family
BPUM_RS06950	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BPUM_RS06955	COG0415	Belongs to the DNA photolyase family
BPUM_RS06960	COG1612	heme a metabolic process
BPUM_RS06965	COG0109	protoheme IX farnesyltransferase activity
BPUM_RS06970	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BPUM_RS06970	COG2010	Cytochrome c
BPUM_RS06975	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BPUM_RS06980	COG1845	cytochrome c oxidase, subunit III
BPUM_RS06985	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BPUM_RS06990	COG3336	cytochrome c oxidase
BPUM_RS07000	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BPUM_RS07005	COG2340	Cysteine-rich secretory protein family
BPUM_RS07025	COG3679	Belongs to the UPF0342 family
BPUM_RS07030	COG4471	UPF0298 protein
BPUM_RS07035	COG0742	ribosomal rna small subunit methyltransferase
BPUM_RS07040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BPUM_RS07045	COG3314	Sporulation integral membrane protein YlbJ
BPUM_RS07050	COG1752	Esterase of the alpha-beta hydrolase superfamily
BPUM_RS07055	COG3480	Lon protease (S16) C-terminal proteolytic domain
BPUM_RS07065	COG1399	metal-binding, possibly nucleic acid-binding protein
BPUM_RS07070	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BPUM_RS07080	COG0454	-acetyltransferase
BPUM_RS07085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BPUM_RS07090	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BPUM_RS07095	COG2001	Belongs to the MraZ family
BPUM_RS07100	COG0275	rRNA processing
BPUM_RS07105	COG4839	cell division protein FtsL
BPUM_RS07110	COG0768	penicillin binding
BPUM_RS07115	COG0768	penicillin binding
BPUM_RS07120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BPUM_RS07125	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BPUM_RS07130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BPUM_RS07135	COG0772	Belongs to the SEDS family
BPUM_RS07140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BPUM_RS07145	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BPUM_RS07150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BPUM_RS07155	COG3879	Bacterial protein of unknown function (DUF881)
BPUM_RS07160	COG3879	Bacterial protein of unknown function (DUF881)
BPUM_RS07165	COG3856	small basic protein
BPUM_RS07170	COG0849	cell division
BPUM_RS07175	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BPUM_RS07180	COG4412	M6 family metalloprotease domain protein
BPUM_RS07180	COG1404	Belongs to the peptidase S8 family
BPUM_RS07190	COG1191	sigma factor activity
BPUM_RS07195	COG1191	sigma factor activity
BPUM_RS07200	COG2390	Transcriptional regulator
BPUM_RS07215	COG3730	PTS system glucitol sorbitol-specific
BPUM_RS07220	COG3732	PTS system glucitol sorbitol-specific
BPUM_RS07230	COG1119	ATPase activity
BPUM_RS07235	COG1873	PFAM PRC-barrel domain
BPUM_RS07240	COG1496	oxidoreductase activity
BPUM_RS07245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BPUM_RS07250	COG1799	cell septum assembly
BPUM_RS07255	COG0762	integral membrane protein
BPUM_RS07260	COG2302	S4 RNA-binding domain
BPUM_RS07265	COG3599	regulation of cell shape
BPUM_RS07270	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BPUM_RS07275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BPUM_RS07280	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BPUM_RS07285	COG0564	pseudouridine synthase activity
BPUM_RS07295	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BPUM_RS07300	COG2233	PERMEase
BPUM_RS07305	COG0540	Belongs to the ATCase OTCase family
BPUM_RS07310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BPUM_RS07315	COG0505	Belongs to the CarA family
BPUM_RS07320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BPUM_RS07325	COG0543	2 iron, 2 sulfur cluster binding
BPUM_RS07330	COG0167	dihydroorotate dehydrogenase activity
BPUM_RS07335	COG0284	orotidine-5'-phosphate decarboxylase activity
BPUM_RS07340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BPUM_RS07345	COG0175	sulfate reduction
BPUM_RS07350	COG0306	phosphate transporter
BPUM_RS07355	COG2046	Belongs to the sulfate adenylyltransferase family
BPUM_RS07360	COG0529	Catalyzes the synthesis of activated sulfate
BPUM_RS07365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BPUM_RS07370	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BPUM_RS07375	COG1648	precorrin-2 dehydrogenase activity
BPUM_RS07385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BPUM_RS07390	COG1561	YicC-like family, N-terminal region
BPUM_RS07395	COG2052	Domain of unknown function (DUF370)
BPUM_RS07400	COG0194	GDP metabolic process
BPUM_RS07405	COG1758	RNA polymerase activity
BPUM_RS07410	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BPUM_RS07415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BPUM_RS07420	COG0242	peptide deformylase activity
BPUM_RS07425	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BPUM_RS07430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BPUM_RS07430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BPUM_RS07435	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BPUM_RS07440	COG0631	protein serine/threonine phosphatase activity
BPUM_RS07445	COG0515	serine threonine protein kinase
BPUM_RS07445	COG2815	serine threonine protein kinase
BPUM_RS07450	COG1162	GTPase activity
BPUM_RS07455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BPUM_RS07460	COG1564	THIamine pyrophosphokinase
BPUM_RS07470	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BPUM_RS07475	COG1302	Protein conserved in bacteria
BPUM_RS07480	COG1461	Dihydroxyacetone kinase
BPUM_RS07485	COG1760	l-serine dehydratase
BPUM_RS07490	COG1760	l-serine dehydratase
BPUM_RS07495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BPUM_RS07500	COG1349	DNA-binding transcription factor activity
BPUM_RS07505	COG0416	fatty acid biosynthetic process
BPUM_RS07510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BPUM_RS07515	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS07520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPUM_RS07530	COG1196	nuclear chromosome segregation
BPUM_RS07535	COG0552	protein localization to endoplasmic reticulum
BPUM_RS07540	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BPUM_RS07545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BPUM_RS07550	COG0228	four-way junction DNA binding
BPUM_RS07555	COG1837	Belongs to the UPF0109 family
BPUM_RS07565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BPUM_RS07570	COG0336	Belongs to the RNA methyltransferase TrmD family
BPUM_RS07575	COG0335	large ribosomal subunit rRNA binding
BPUM_RS07580	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BPUM_RS07585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPUM_RS07595	COG2257	FlhB HrpN YscU SpaS Family
BPUM_RS07600	COG0045	succinate-CoA ligase (ADP-forming) activity
BPUM_RS07605	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BPUM_RS07610	COG0758	DNA mediated transformation
BPUM_RS07615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BPUM_RS07620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BPUM_RS07625	COG4974	Belongs to the 'phage' integrase family
BPUM_RS07630	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BPUM_RS07635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BPUM_RS07640	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BPUM_RS07645	COG1815	bacterial-type flagellum-dependent cell motility
BPUM_RS07650	COG1558	bacterial-type flagellum-dependent cell motility
BPUM_RS07655	COG1677	Flagellar hook-basal body complex protein FliE
BPUM_RS07660	COG1766	The M ring may be actively involved in energy transduction
BPUM_RS07665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BPUM_RS07670	COG1317	bacterial-type flagellum organization
BPUM_RS07675	COG1157	protein secretion by the type III secretion system
BPUM_RS07680	COG2882	bacterial-type flagellum organization
BPUM_RS07685	COG3334	PFAM MgtE intracellular
BPUM_RS07690	COG3144	bacterial-type flagellum assembly
BPUM_RS07695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BPUM_RS07700	COG4786	Flagellar basal body rod
BPUM_RS07705	COG1582	Flagellar protein (FlbD)
BPUM_RS07710	COG1580	Controls the rotational direction of flagella during chemotaxis
BPUM_RS07715	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BPUM_RS07720	COG1776	CheC inhibitor of MCP methylation
BPUM_RS07720	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BPUM_RS07725	COG2201	protein-glutamate methylesterase activity
BPUM_RS07730	COG3190	flagellar
BPUM_RS07735	COG1338	Plays a role in the flagellum-specific transport system
BPUM_RS07740	COG1987	bacterial-type flagellum assembly
BPUM_RS07745	COG1684	flagellar biosynthetic protein fliR
BPUM_RS07750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BPUM_RS07755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BPUM_RS07760	COG1419	protein localization to endoplasmic reticulum
BPUM_RS07765	COG0455	bacterial-type flagellum organization
BPUM_RS07770	COG2201	protein-glutamate methylesterase activity
BPUM_RS07775	COG0643	Histidine kinase
BPUM_RS07775	COG2198	Histidine kinase
BPUM_RS07780	COG0835	chemotaxis
BPUM_RS07785	COG1776	CheC inhibitor of MCP methylation
BPUM_RS07795	COG1191	sigma factor activity
BPUM_RS07810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BPUM_RS07820	COG0233	cytoplasmic translational termination
BPUM_RS07825	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BPUM_RS07830	COG4589	Belongs to the CDS family
BPUM_RS07835	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BPUM_RS07840	COG0750	zinc metalloprotease
BPUM_RS07845	COG0442	prolyl-tRNA aminoacylation
BPUM_RS07850	COG2176	DNA-directed DNA polymerase activity
BPUM_RS07865	COG3693	PFAM glycoside hydrolase, family 10
BPUM_RS07875	COG0779	Required for maturation of 30S ribosomal subunits
BPUM_RS07880	COG0195	Participates in both transcription termination and antitermination
BPUM_RS07885	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BPUM_RS07890	COG1358	cellular component organization or biogenesis
BPUM_RS07895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BPUM_RS07900	COG1550	Protein conserved in bacteria
BPUM_RS07905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BPUM_RS07910	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BPUM_RS07915	COG0196	riboflavin kinase activity
BPUM_RS07920	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BPUM_RS07925	COG1185	polyribonucleotide nucleotidyltransferase activity
BPUM_RS07930	COG0726	polysaccharide deacetylase
BPUM_RS07935	COG0612	Peptidase, M16
BPUM_RS07945	COG1873	PFAM PRC-barrel domain
BPUM_RS07950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPUM_RS07955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BPUM_RS07960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BPUM_RS07965	COG0527	aspartate kinase activity
BPUM_RS07975	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BPUM_RS07980	COG0740	serine-type endopeptidase activity
BPUM_RS07990	COG4980	gas vesicle protein
BPUM_RS07990	COG1674	ftsk spoiiie
BPUM_RS07995	COG2188	Transcriptional regulator
BPUM_RS08000	COG2814	Major facilitator Superfamily
BPUM_RS08005	COG1033	growth of symbiont in host cell
BPUM_RS08005	COG2409	Drug exporters of the RND superfamily
BPUM_RS08010	COG0612	Peptidase, M16
BPUM_RS08015	COG0612	Peptidase, M16
BPUM_RS08025	COG1033	growth of symbiont in host cell
BPUM_RS08025	COG2409	Drug exporters of the RND superfamily
BPUM_RS08030	COG0300	oxidoreductase activity
BPUM_RS08045	COG1426	Protein conserved in bacteria
BPUM_RS08050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BPUM_RS08055	COG1546	Belongs to the CinA family
BPUM_RS08055	COG1058	Belongs to the CinA family
BPUM_RS08060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BPUM_RS08065	COG1418	mRNA catabolic process
BPUM_RS08070	COG1692	metallophosphoesterase
BPUM_RS08075	COG2359	stage V sporulation protein S
BPUM_RS08080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BPUM_RS08085	COG1063	alcohol dehydrogenase
BPUM_RS08090	COG0156	8-amino-7-oxononanoate synthase activity
BPUM_RS08095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BPUM_RS08100	COG4550	Control of competence regulator ComK, YlbF/YmcA
BPUM_RS08110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BPUM_RS08115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BPUM_RS08135	COG1329	Transcriptional regulator
BPUM_RS08140	COG4195	phage-related replication protein
BPUM_RS08145	COG0457	Tetratricopeptide repeat
BPUM_RS08150	COG1404	Belongs to the peptidase S8 family
BPUM_RS08155	COG4195	phage-related replication protein
BPUM_RS08160	COG1764	response to oxidative stress
BPUM_RS08165	COG2076	Multidrug Resistance protein
BPUM_RS08190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BPUM_RS08195	COG1923	regulation of RNA biosynthetic process
BPUM_RS08210	COG1780	Probably involved in ribonucleotide reductase function
BPUM_RS08215	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPUM_RS08220	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BPUM_RS08225	COG4112	unkown
BPUM_RS08235	COG0464	growth
BPUM_RS08240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BPUM_RS08245	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BPUM_RS08250	COG0789	Transcriptional regulator
BPUM_RS08255	COG0174	glutamine synthetase
BPUM_RS08265	COG1752	Esterase of the alpha-beta hydrolase superfamily
BPUM_RS08315	COG0457	Tetratricopeptide repeat
BPUM_RS08320	COG5444	nuclease activity
BPUM_RS08330	COG5444	nuclease activity
BPUM_RS08355	COG5646	InterPro IPR014922
BPUM_RS08375	COG0457	Tetratricopeptide repeat
BPUM_RS08385	COG3619	membrane
BPUM_RS08390	COG3285	dna ligase
BPUM_RS08390	COG1793	dna ligase
BPUM_RS08395	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BPUM_RS08400	COG4876	unkown
BPUM_RS08410	COG1959	2 iron, 2 sulfur cluster binding
BPUM_RS08415	COG0702	epimerase
BPUM_RS08420	COG0247	lactate metabolic process
BPUM_RS08425	COG1139	Iron-sulfur cluster binding protein
BPUM_RS08430	COG1556	Lactate utilization protein
BPUM_RS08455	COG1309	transcriptional regulator
BPUM_RS08460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BPUM_RS08460	COG2124	cytochrome p450
BPUM_RS08465	COG3591	Belongs to the peptidase S1B family
BPUM_RS08470	COG3209	COG3209 Rhs family protein
BPUM_RS08475	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS08490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BPUM_RS08495	COG1388	LysM domain
BPUM_RS08500	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BPUM_RS08505	COG4224	UPF0291 protein
BPUM_RS08510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BPUM_RS08520	COG3763	UPF0154 protein
BPUM_RS08530	COG0785	Cytochrome C biogenesis protein
BPUM_RS08535	COG4846	Membrane protein involved in cytochrome C biogenesis
BPUM_RS08545	COG0071	Belongs to the small heat shock protein (HSP20) family
BPUM_RS08560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BPUM_RS08565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS08580	COG0824	Thioesterase
BPUM_RS08590	COG4841	protein insertion into membrane
BPUM_RS08595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BPUM_RS08600	COG1832	CoA-binding protein
BPUM_RS08610	COG0187	DNA topoisomerase II activity
BPUM_RS08615	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BPUM_RS08625	COG0738	Major facilitator superfamily
BPUM_RS08645	COG0604	alcohol dehydrogenase
BPUM_RS08660	COG2249	NAD(P)H dehydrogenase (quinone) activity
BPUM_RS08665	COG1733	regulation of RNA biosynthetic process
BPUM_RS08670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BPUM_RS08675	COG0251	oxidation-reduction process
BPUM_RS08715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BPUM_RS08745	COG0657	acetylesterase activity
BPUM_RS08755	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS08760	COG2190	(PTS) system
BPUM_RS08760	COG1263	PTS System
BPUM_RS08760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS08775	COG2205	protein histidine kinase activity
BPUM_RS08780	COG0745	RESPONSE REGULATOR receiver
BPUM_RS08790	COG3507	Belongs to the glycosyl hydrolase 43 family
BPUM_RS08795	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS08800	COG1486	melibiose metabolic process
BPUM_RS08805	COG0395	ABC-type sugar transport system, permease component
BPUM_RS08810	COG1175	transmembrane transport
BPUM_RS08815	COG1653	transport
BPUM_RS08820	COG1609	Transcriptional regulator
BPUM_RS08825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BPUM_RS08840	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS08865	COG5444	nuclease activity
BPUM_RS08870	COG1846	Transcriptional regulator
BPUM_RS08875	COG2814	Major facilitator Superfamily
BPUM_RS08885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS08885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS08885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS08890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS08890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS08890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BPUM_RS08895	COG1105	Belongs to the carbohydrate kinase PfkB family
BPUM_RS08905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPUM_RS08925	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS08930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BPUM_RS08935	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BPUM_RS08940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BPUM_RS08945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BPUM_RS08950	COG1024	Enoyl-CoA hydratase
BPUM_RS08955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BPUM_RS08960	COG0511	ligase activity, forming carbon-carbon bonds
BPUM_RS08965	COG0439	Biotin carboxylase
BPUM_RS08970	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS08975	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS08980	COG1649	PFAM Uncharacterised BCR, COG1649
BPUM_RS08985	COG2365	Tyrosine phosphatase family
BPUM_RS08990	COG1349	DNA-binding transcription factor activity
BPUM_RS09000	COG3835	regulator
BPUM_RS09005	COG0277	FAD linked oxidase domain protein
BPUM_RS09010	COG0247	lactate metabolic process
BPUM_RS09040	COG0166	Belongs to the GPI family
BPUM_RS09045	COG0586	Pfam SNARE associated Golgi protein
BPUM_RS09050	COG1587	Uroporphyrinogen-III synthase
BPUM_RS09060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BPUM_RS09075	COG0534	Mate efflux family protein
BPUM_RS09080	COG2027	D-alanyl-D-alanine carboxypeptidase
BPUM_RS09085	COG4677	pectinesterase activity
BPUM_RS09090	COG2323	membrane
BPUM_RS09095	COG2146	nitrite reductase [NAD(P)H] activity
BPUM_RS09100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BPUM_RS09110	COG0493	'glutamate synthase
BPUM_RS09115	COG0069	glutamate synthase activity
BPUM_RS09115	COG0070	glutamate synthase
BPUM_RS09115	COG0067	glutamate synthase
BPUM_RS09120	COG0583	DNA-binding transcription factor activity
BPUM_RS09130	COG1132	(ABC) transporter
BPUM_RS09140	COG0454	-acetyltransferase
BPUM_RS09150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS09155	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BPUM_RS09160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BPUM_RS09175	COG0243	molybdopterin cofactor binding
BPUM_RS09185	COG1070	Carbohydrate kinase
BPUM_RS09190	COG2115	Belongs to the xylose isomerase family
BPUM_RS09195	COG1940	carbohydrate kinase activity
BPUM_RS09205	COG2211	Major facilitator Superfamily
BPUM_RS09210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPUM_RS09215	COG1994	Peptidase M50
BPUM_RS09235	COG1309	transcriptional regulator
BPUM_RS09240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BPUM_RS09245	COG3708	Transcriptional regulator
BPUM_RS09250	COG2378	regulation of single-species biofilm formation
BPUM_RS09260	COG0640	Transcriptional regulator
BPUM_RS09265	COG0531	amino acid
BPUM_RS09270	COG0741	lytic transglycosylase activity
BPUM_RS09275	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BPUM_RS09280	COG2079	MmgE PrpD family protein
BPUM_RS09285	COG0372	Belongs to the citrate synthase family
BPUM_RS09290	COG2322	membrane
BPUM_RS09300	COG1388	LysM domain
BPUM_RS09300	COG3584	3D domain protein
BPUM_RS09305	COG0514	ATP-dependent DNA helicase (RecQ)
BPUM_RS09315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BPUM_RS09335	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS09340	COG1657	PFAM Prenyltransferase squalene oxidase
BPUM_RS09345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BPUM_RS09350	COG0385	Bile acid
BPUM_RS09355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS09360	COG0567	Dehydrogenase, E1 component
BPUM_RS09365	COG4548	von Willebrand factor, type A
BPUM_RS09370	COG0714	Associated with various cellular activities
BPUM_RS09375	COG2032	superoxide dismutase activity
BPUM_RS09390	COG0534	Mate efflux family protein
BPUM_RS09395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BPUM_RS09400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BPUM_RS09410	COG2962	Rard protein
BPUM_RS09425	COG1733	regulation of RNA biosynthetic process
BPUM_RS09430	COG0778	Nitroreductase
BPUM_RS09440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BPUM_RS09445	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BPUM_RS09450	COG0793	Belongs to the peptidase S41A family
BPUM_RS09450	COG3409	Peptidoglycan-binding domain 1 protein
BPUM_RS09455	COG2226	methyltransferase
BPUM_RS09465	COG1876	peptidase activity
BPUM_RS09470	COG0813	purine-nucleoside phosphorylase activity
BPUM_RS09480	COG0671	phosphoesterase, PA-phosphatase related
BPUM_RS09490	COG4479	Belongs to the UPF0346 family
BPUM_RS09500	COG1509	lysine 2,3-aminomutase activity
BPUM_RS09505	COG3829	transcription factor binding
BPUM_RS09510	COG0463	Glycosyl transferase, family 2
BPUM_RS09525	COG4641	Protein conserved in bacteria
BPUM_RS09535	COG1086	Polysaccharide biosynthesis protein
BPUM_RS09540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BPUM_RS09545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BPUM_RS09550	COG1846	Transcriptional regulator
BPUM_RS09570	COG4698	Protein conserved in bacteria
BPUM_RS09575	COG2755	lipolytic protein G-D-S-L family
BPUM_RS09580	COG1999	signal sequence binding
BPUM_RS09595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BPUM_RS09600	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BPUM_RS09605	COG1272	protein, Hemolysin III
BPUM_RS09610	COG0204	Acyl-transferase
BPUM_RS09615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BPUM_RS09620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BPUM_RS09625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BPUM_RS09635	COG2521	methyltransferase
BPUM_RS09635	COG2136	Putative SAM-dependent methyltransferase
BPUM_RS09645	COG0129	dihydroxy-acid dehydratase activity
BPUM_RS09650	COG1413	lyase activity
BPUM_RS09655	COG1418	mRNA catabolic process
BPUM_RS09660	COG0386	Belongs to the glutathione peroxidase family
BPUM_RS09665	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BPUM_RS09670	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BPUM_RS09675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BPUM_RS09685	COG1278	Cold shock
BPUM_RS09700	COG0328	RNA-DNA hybrid ribonuclease activity
BPUM_RS09705	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BPUM_RS09710	COG0328	RNA-DNA hybrid ribonuclease activity
BPUM_RS09720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BPUM_RS09730	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BPUM_RS09735	COG1755	Isoprenylcysteine carboxyl methyltransferase
BPUM_RS09740	COG3424	synthase
BPUM_RS09745	COG0726	polysaccharide deacetylase
BPUM_RS09750	COG2233	PERMEase
BPUM_RS09755	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BPUM_RS09760	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BPUM_RS09765	COG1199	ATP-dependent helicase activity
BPUM_RS09775	COG2801	Transposase and inactivated derivatives
BPUM_RS09785	COG0116	Belongs to the methyltransferase superfamily
BPUM_RS09795	COG3599	regulation of cell shape
BPUM_RS09800	COG4474	Belongs to the UPF0398 family
BPUM_RS09805	COG3359	exonuclease
BPUM_RS09810	COG1205	dead DEAH box helicase
BPUM_RS09810	COG1111	helicase
BPUM_RS09815	COG1902	pentaerythritol trinitrate reductase activity
BPUM_RS09820	COG2190	(PTS) system
BPUM_RS09825	COG0071	Belongs to the small heat shock protein (HSP20) family
BPUM_RS09855	COG3331	DNA recombination
BPUM_RS09860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BPUM_RS09860	COG4499	WXG100 protein secretion system (Wss), protein YukC
BPUM_RS09870	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BPUM_RS09875	COG3935	DnaD domain protein
BPUM_RS09880	COG0017	Asparaginyl-tRNA synthetase
BPUM_RS09885	COG5353	protein conserved in bacteria
BPUM_RS09890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BPUM_RS09890	COG1199	ATP-dependent helicase activity
BPUM_RS09895	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BPUM_RS09900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BPUM_RS09905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BPUM_RS09915	COG0617	tRNA 3'-terminal CCA addition
BPUM_RS09920	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS09925	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BPUM_RS09930	COG1803	Methylglyoxal synthase
BPUM_RS09935	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BPUM_RS09940	COG1694	Mazg nucleotide pyrophosphohydrolase
BPUM_RS09945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BPUM_RS09955	COG4347	Protein of unknown function (DUF1405)
BPUM_RS09960	COG2010	Cytochrome c
BPUM_RS09960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BPUM_RS09965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BPUM_RS09970	COG0723	plastoquinol--plastocyanin reductase activity
BPUM_RS09980	COG5582	Belongs to the UPF0302 family
BPUM_RS09985	COG0457	Tetratricopeptide repeat
BPUM_RS09990	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BPUM_RS09995	COG0287	Prephenate dehydrogenase
BPUM_RS10000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BPUM_RS10005	COG0159	tryptophan synthase activity
BPUM_RS10010	COG0133	tryptophan synthase activity
BPUM_RS10015	COG0135	phosphoribosylanthranilate isomerase activity
BPUM_RS10020	COG0134	indole-3-glycerol-phosphate synthase activity
BPUM_RS10025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BPUM_RS10035	COG4401	Chorismate mutase type I
BPUM_RS10040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BPUM_RS10045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BPUM_RS10050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BPUM_RS10055	COG0105	UTP biosynthetic process
BPUM_RS10060	COG0142	geranyltranstransferase activity
BPUM_RS10065	COG2226	methyltransferase
BPUM_RS10070	COG0142	geranyltranstransferase activity
BPUM_RS10080	COG0302	gtp cyclohydrolase
BPUM_RS10085	COG0776	regulation of translation
BPUM_RS10090	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BPUM_RS10105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BPUM_RS10110	COG1160	GTP binding
BPUM_RS10130	COG1304	FMN binding
BPUM_RS10135	COG0539	negative regulation of cytoplasmic translation
BPUM_RS10140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BPUM_RS10150	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BPUM_RS10155	COG2959	enzyme of heme biosynthesis
BPUM_RS10160	COG3773	Cell wall hydrolase
BPUM_RS10160	COG3409	Peptidoglycan-binding domain 1 protein
BPUM_RS10165	COG2339	peptidase activity
BPUM_RS10170	COG0492	ferredoxin-NADP+ reductase activity
BPUM_RS10175	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BPUM_RS10180	COG4862	establishment of competence for transformation
BPUM_RS10185	COG1408	metallophosphoesterase
BPUM_RS10195	COG1388	LysM domain
BPUM_RS10200	COG1266	CAAX protease self-immunity
BPUM_RS10205	COG0514	ATP-dependent DNA helicase (RecQ)
BPUM_RS10210	COG4955	Helix-turn-helix domain
BPUM_RS10215	COG1141	Ferredoxin
BPUM_RS10220	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BPUM_RS10225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BPUM_RS10230	COG5632	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS10230	COG3409	Peptidoglycan-binding domain 1 protein
BPUM_RS10240	COG1595	DNA-templated transcription, initiation
BPUM_RS10245	COG5002	protein histidine kinase activity
BPUM_RS10250	COG0745	RESPONSE REGULATOR receiver
BPUM_RS10255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BPUM_RS10260	COG1333	cytochrome c biogenesis protein
BPUM_RS10265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS10270	COG1187	pseudouridine synthase activity
BPUM_RS10275	COG0700	Nucleoside recognition
BPUM_RS10280	COG2715	membrane protein required for spore maturation
BPUM_RS10285	COG1686	Belongs to the peptidase S11 family
BPUM_RS10295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BPUM_RS10300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BPUM_RS10305	COG1547	Domain of unknown function (DUF309)
BPUM_RS10310	COG0456	acetyltransferase
BPUM_RS10315	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BPUM_RS10325	COG0307	riboflavin synthase, alpha
BPUM_RS10345	COG2814	Major facilitator Superfamily
BPUM_RS10350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BPUM_RS10355	COG4086	secreted protein
BPUM_RS10360	COG0019	diaminopimelate decarboxylase activity
BPUM_RS10365	COG0697	spore germination
BPUM_RS10380	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BPUM_RS10400	COG1191	sigma factor activity
BPUM_RS10405	COG2172	sigma factor antagonist activity
BPUM_RS10415	COG1686	Belongs to the peptidase S11 family
BPUM_RS10420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BPUM_RS10425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BPUM_RS10430	COG4974	Belongs to the 'phage' integrase family
BPUM_RS10440	COG0735	belongs to the Fur family
BPUM_RS10445	COG1300	Membrane
BPUM_RS10460	COG2153	protein acetylation
BPUM_RS10465	COG1379	DNA repair
BPUM_RS10470	COG0494	nUDIX hydrolase
BPUM_RS10475	COG0667	Aldo Keto reductase
BPUM_RS10490	COG1073	alpha beta
BPUM_RS10495	COG0457	Tetratricopeptide repeat
BPUM_RS10505	COG4918	Iron-sulphur cluster biosynthesis
BPUM_RS10510	COG0456	acetyltransferase
BPUM_RS10510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BPUM_RS10515	COG0456	acetyltransferase
BPUM_RS10525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BPUM_RS10535	COG2211	Major facilitator Superfamily
BPUM_RS10540	COG1072	(Pantothenic acid kinase))
BPUM_RS10545	COG0446	pyridine nucleotide-disulphide oxidoreductase
BPUM_RS10550	COG0300	oxidoreductase activity
BPUM_RS10555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BPUM_RS10560	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BPUM_RS10570	COG4187	Peptidase family M20/M25/M40
BPUM_RS10575	COG1902	pentaerythritol trinitrate reductase activity
BPUM_RS10580	COG0596	Alpha beta hydrolase
BPUM_RS10585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BPUM_RS10590	COG1234	tRNA 3'-trailer cleavage
BPUM_RS10595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BPUM_RS10600	COG2188	Transcriptional regulator
BPUM_RS10605	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS10610	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS10615	COG1447	Phosphotransferase system cellobiose-specific component IIA
BPUM_RS10620	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS10630	COG4975	Glucose uptake
BPUM_RS10635	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BPUM_RS10640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BPUM_RS10655	COG0706	membrane insertase activity
BPUM_RS10665	COG2195	Cleaves the N-terminal amino acid of tripeptides
BPUM_RS10670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BPUM_RS10675	COG0346	lactoylglutathione lyase activity
BPUM_RS10680	COG1376	ErfK ybiS ycfS ynhG family protein
BPUM_RS10685	COG4129	membrane
BPUM_RS10690	COG1126	abc transporter atp-binding protein
BPUM_RS10695	COG0765	amino acid transport
BPUM_RS10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS10710	COG1597	lipid kinase activity
BPUM_RS10720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BPUM_RS10725	COG0022	dehydrogenase e1 component
BPUM_RS10730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BPUM_RS10735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BPUM_RS10740	COG3426	butyrate kinase activity
BPUM_RS10745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BPUM_RS10750	COG0280	phosphate acetyltransferase
BPUM_RS10755	COG3290	protein histidine kinase activity
BPUM_RS10755	COG3829	transcription factor binding
BPUM_RS10765	COG0584	glycerophosphoryl diester phosphodiesterase
BPUM_RS10770	COG0457	Tetratricopeptide repeat
BPUM_RS10780	COG0745	RESPONSE REGULATOR receiver
BPUM_RS10785	COG0750	zinc metalloprotease
BPUM_RS10790	COG0497	DNA recombination
BPUM_RS10795	COG1438	arginine binding
BPUM_RS10800	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BPUM_RS10805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BPUM_RS10810	COG0142	geranyltranstransferase activity
BPUM_RS10815	COG1722	exodeoxyribonuclease VII activity
BPUM_RS10820	COG1570	exodeoxyribonuclease VII activity
BPUM_RS10825	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BPUM_RS10830	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BPUM_RS10835	COG1302	Protein conserved in bacteria
BPUM_RS10840	COG0439	Biotin carboxylase
BPUM_RS10845	COG0511	ligase activity, forming carbon-carbon bonds
BPUM_RS10885	COG3854	ATPases associated with a variety of cellular activities
BPUM_RS10895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BPUM_RS10900	COG0006	proline dipeptidase activity
BPUM_RS10905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BPUM_RS10915	COG3872	metal-dependent enzyme
BPUM_RS10925	COG1752	Esterase of the alpha-beta hydrolase superfamily
BPUM_RS10930	COG1321	iron dependent repressor
BPUM_RS10935	COG0095	Lipoate-protein ligase
BPUM_RS10940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPUM_RS10945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BPUM_RS10950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BPUM_RS10955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BPUM_RS10960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BPUM_RS10970	COG1396	sequence-specific DNA binding
BPUM_RS10980	COG0681	Belongs to the peptidase S26 family
BPUM_RS11015	COG4970	Tfp pilus assembly protein FimT
BPUM_RS11020	COG4537	Required for transformation and DNA binding
BPUM_RS11025	COG1459	type II secretion system
BPUM_RS11030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BPUM_RS11035	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS11045	COG1393	Belongs to the ArsC family
BPUM_RS11055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BPUM_RS11060	COG0011	TIGRFAM Protein of
BPUM_RS11065	COG2814	Major facilitator Superfamily
BPUM_RS11070	COG2866	Carboxypeptidase
BPUM_RS11075	COG1368	sulfuric ester hydrolase activity
BPUM_RS11080	COG1940	carbohydrate kinase activity
BPUM_RS11085	COG4483	Protein conserved in bacteria
BPUM_RS11090	COG0457	Tetratricopeptide repeat
BPUM_RS11090	COG0705	Rhomboid family
BPUM_RS11095	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BPUM_RS11100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BPUM_RS11110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BPUM_RS11115	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BPUM_RS11120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BPUM_RS11125	COG0581	inorganic phosphate transmembrane transporter activity
BPUM_RS11130	COG0573	inorganic phosphate transmembrane transporter activity
BPUM_RS11135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BPUM_RS11140	COG0768	penicillin binding
BPUM_RS11145	COG0477	Major facilitator Superfamily
BPUM_RS11150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BPUM_RS11155	COG2839	Protein conserved in bacteria
BPUM_RS11160	COG5521	maltodextrose utilization protein MalA
BPUM_RS11165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BPUM_RS11170	COG1388	LysM domain
BPUM_RS11175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BPUM_RS11180	COG4709	membrane
BPUM_RS11185	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BPUM_RS11190	COG1940	carbohydrate kinase activity
BPUM_RS11200	COG0735	belongs to the Fur family
BPUM_RS11205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BPUM_RS11210	COG1121	(ABC) transporter
BPUM_RS11215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BPUM_RS11225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BPUM_RS11230	COG0513	Belongs to the DEAD box helicase family
BPUM_RS11240	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BPUM_RS11245	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BPUM_RS11250	COG2384	SAM-dependent methyltransferase
BPUM_RS11255	COG2010	Cytochrome c
BPUM_RS11260	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BPUM_RS11265	COG0358	DNA primase activity
BPUM_RS11270	COG1671	Belongs to the UPF0178 family
BPUM_RS11275	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BPUM_RS11280	COG0517	IMP dehydrogenase activity
BPUM_RS11285	COG0751	glycine-tRNA ligase activity
BPUM_RS11290	COG0752	glycyl-tRNA synthetase alpha subunit
BPUM_RS11295	COG1381	Involved in DNA repair and RecF pathway recombination
BPUM_RS11305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BPUM_RS11310	COG0295	cytidine deaminase activity
BPUM_RS11315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BPUM_RS11320	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BPUM_RS11325	COG1480	7TM receptor with intracellular HD hydrolase
BPUM_RS11330	COG1702	phosphate starvation-inducible protein PhoH
BPUM_RS11335	COG0561	phosphatase activity
BPUM_RS11355	COG4864	UPF0365 protein
BPUM_RS11360	COG1030	water channel activity
BPUM_RS11365	COG1610	YqeY-like protein
BPUM_RS11375	COG1283	sodium-dependent phosphate transmembrane transporter activity
BPUM_RS11380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BPUM_RS11385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BPUM_RS11390	COG2264	protein methyltransferase activity
BPUM_RS11395	COG0484	heat shock protein binding
BPUM_RS11400	COG0443	Heat shock 70 kDa protein
BPUM_RS11405	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BPUM_RS11410	COG1420	regulation of RNA biosynthetic process
BPUM_RS11415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BPUM_RS11420	COG0481	GTPase activity
BPUM_RS11430	COG0860	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS11435	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BPUM_RS11440	COG0268	Binds directly to 16S ribosomal RNA
BPUM_RS11445	COG1466	dna polymerase III delta subunit
BPUM_RS11450	COG0658	competence protein
BPUM_RS11450	COG2333	competence protein COMEC
BPUM_RS11455	COG2131	deaminase
BPUM_RS11460	COG1555	photosystem II stabilization
BPUM_RS11465	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BPUM_RS11470	COG2226	methyltransferase
BPUM_RS11475	COG0799	negative regulation of ribosome biogenesis
BPUM_RS11480	COG1713	HD superfamily hydrolase involved in NAD metabolism
BPUM_RS11485	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BPUM_RS11490	COG1534	Rna-binding protein
BPUM_RS11495	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BPUM_RS11500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BPUM_RS11505	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BPUM_RS11515	COG2755	lipolytic protein G-D-S-L family
BPUM_RS11525	COG0457	Tetratricopeptide repeat
BPUM_RS11580	COG0726	polysaccharide deacetylase
BPUM_RS11610	COG2160	L-arabinose isomerase activity
BPUM_RS11625	COG1609	Transcriptional regulator
BPUM_RS11635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BPUM_RS11640	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BPUM_RS11645	COG1733	regulation of RNA biosynthetic process
BPUM_RS11650	COG0657	acetylesterase activity
BPUM_RS11665	COG3209	COG3209 Rhs family protein
BPUM_RS11670	COG2602	Beta-lactamase
BPUM_RS11675	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS11680	COG1126	abc transporter atp-binding protein
BPUM_RS11685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS11690	COG0765	amino acid transport
BPUM_RS11700	COG3546	catalase activity
BPUM_RS11705	COG1063	alcohol dehydrogenase
BPUM_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS11725	COG1115	amino acid carrier protein
BPUM_RS11730	COG0583	DNA-binding transcription factor activity
BPUM_RS11735	COG1132	(ABC) transporter
BPUM_RS11740	COG0454	-acetyltransferase
BPUM_RS11745	COG1063	alcohol dehydrogenase
BPUM_RS11750	COG2226	methyltransferase
BPUM_RS11760	COG0626	cystathionine gamma-synthase activity
BPUM_RS11765	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BPUM_RS11770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BPUM_RS11775	COG2226	methyltransferase
BPUM_RS11790	COG0768	penicillin binding
BPUM_RS11795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BPUM_RS11805	COG0572	uridine kinase
BPUM_RS11810	COG0826	peptidase U32
BPUM_RS11815	COG0826	peptidase U32
BPUM_RS11820	COG4122	O-methyltransferase activity
BPUM_RS11825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BPUM_RS11830	COG0183	Belongs to the thiolase family
BPUM_RS11835	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS11840	COG1268	BioY protein
BPUM_RS11845	COG3906	Belongs to the UPF0473 family
BPUM_RS11850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BPUM_RS11855	COG4472	Bacterial protein of unknown function (DUF965)
BPUM_RS11860	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BPUM_RS11865	COG0628	permease
BPUM_RS11870	COG1126	abc transporter atp-binding protein
BPUM_RS11875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS11880	COG0765	amino acid transport
BPUM_RS11885	COG0765	amino acid transport
BPUM_RS11895	COG3881	PFAM PRC-barrel domain
BPUM_RS11900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BPUM_RS11905	COG0457	Tetratricopeptide repeat
BPUM_RS11910	COG0482	sulfurtransferase activity
BPUM_RS11915	COG1104	cysteine desulfurase activity
BPUM_RS11920	COG1959	2 iron, 2 sulfur cluster binding
BPUM_RS11925	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BPUM_RS11930	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BPUM_RS11945	COG0124	histidyl-tRNA synthetase
BPUM_RS11950	COG0860	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS11950	COG4991	sh3 domain protein
BPUM_RS11950	COG3103	Sh3 type 3 domain protein
BPUM_RS11955	COG1490	D-aminoacyl-tRNA deacylase activity
BPUM_RS11960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BPUM_RS11965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BPUM_RS11970	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BPUM_RS11970	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BPUM_RS11975	COG5416	Lipopolysaccharide assembly protein A domain
BPUM_RS11980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BPUM_RS11980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BPUM_RS11990	COG2244	polysaccharide biosynthetic process
BPUM_RS11995	COG2323	membrane
BPUM_RS12005	COG1862	Preprotein translocase
BPUM_RS12010	COG0343	queuine tRNA-ribosyltransferase activity
BPUM_RS12015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BPUM_RS12025	COG2255	four-way junction helicase activity
BPUM_RS12030	COG0632	four-way junction helicase activity
BPUM_RS12040	COG2112	serine threonine protein kinase
BPUM_RS12050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BPUM_RS12065	COG1388	LysM domain
BPUM_RS12070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BPUM_RS12075	COG0157	Belongs to the NadC ModD family
BPUM_RS12080	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BPUM_RS12090	COG1827	regulation of RNA biosynthetic process
BPUM_RS12095	COG0077	Prephenate dehydratase
BPUM_RS12100	COG4492	Belongs to the UPF0735 family
BPUM_RS12105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BPUM_RS12110	COG3290	protein histidine kinase activity
BPUM_RS12115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BPUM_RS12120	COG2868	ribosomal protein
BPUM_RS12125	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BPUM_RS12130	COG1994	Peptidase M50
BPUM_RS12135	COG0739	heme binding
BPUM_RS12140	COG2894	cell division
BPUM_RS12145	COG0850	regulation of cytokinetic process
BPUM_RS12150	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BPUM_RS12160	COG1077	Cell shape determining protein MreB Mrl
BPUM_RS12165	COG2003	Belongs to the UPF0758 family
BPUM_RS12170	COG0424	maF-like protein
BPUM_RS12180	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BPUM_RS12185	COG0285	dihydrofolate synthase activity
BPUM_RS12190	COG0525	valine-tRNA ligase activity
BPUM_RS12200	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BPUM_RS12205	COG1388	LysM domain
BPUM_RS12210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BPUM_RS12215	COG0113	porphobilinogen synthase activity
BPUM_RS12220	COG1587	Uroporphyrinogen-III synthase
BPUM_RS12225	COG0181	hydroxymethylbilane synthase activity
BPUM_RS12230	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BPUM_RS12235	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BPUM_RS12245	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BPUM_RS12250	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BPUM_RS12255	COG1067	ATP-dependent peptidase activity
BPUM_RS12255	COG0470	DNA polymerase III
BPUM_RS12260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BPUM_RS12265	COG0544	peptidyl-prolyl cis-trans isomerase activity
BPUM_RS12270	COG1477	protein flavinylation
BPUM_RS12270	COG0457	Tetratricopeptide repeat
BPUM_RS12275	COG0066	3-isopropylmalate dehydratase activity
BPUM_RS12280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BPUM_RS12285	COG0473	3-isopropylmalate dehydrogenase activity
BPUM_RS12290	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BPUM_RS12295	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BPUM_RS12300	COG0440	acetolactate synthase activity
BPUM_RS12305	COG0028	Belongs to the TPP enzyme family
BPUM_RS12310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BPUM_RS12315	COG2706	6-phosphogluconolactonase activity
BPUM_RS12320	COG3339	Conserved Protein
BPUM_RS12325	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BPUM_RS12330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BPUM_RS12335	COG1696	Membrane protein involved in D-alanine export
BPUM_RS12350	COG0346	lactoylglutathione lyase activity
BPUM_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS12390	COG0622	Phosphoesterase
BPUM_RS12395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BPUM_RS12400	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BPUM_RS12405	COG5401	PFAM Sporulation and spore germination
BPUM_RS12410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BPUM_RS12415	COG1846	Transcriptional regulator
BPUM_RS12420	COG2197	response regulator
BPUM_RS12425	COG2851	Citrate transporter
BPUM_RS12430	COG0583	DNA-binding transcription factor activity
BPUM_RS12435	COG2828	Protein conserved in bacteria
BPUM_RS12445	COG0824	Thioesterase
BPUM_RS12450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BPUM_RS12455	COG1053	succinate dehydrogenase
BPUM_RS12460	COG2009	succinate dehydrogenase
BPUM_RS12465	COG1719	4-vinyl reductase, 4VR
BPUM_RS12470	COG0527	aspartate kinase activity
BPUM_RS12475	COG0322	excinuclease ABC activity
BPUM_RS12480	COG3118	belongs to the thioredoxin family
BPUM_RS12485	COG3534	alpha-L-arabinofuranosidase
BPUM_RS12490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BPUM_RS12495	COG2086	electron transfer activity
BPUM_RS12500	COG1024	Enoyl-CoA hydratase
BPUM_RS12505	COG1309	transcriptional regulator
BPUM_RS12510	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS12520	COG3766	membrane
BPUM_RS12525	COG1193	negative regulation of DNA recombination
BPUM_RS12530	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BPUM_RS12530	COG1796	DNA polymerase
BPUM_RS12535	COG1286	toxin biosynthetic process
BPUM_RS12540	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BPUM_RS12545	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BPUM_RS12550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPUM_RS12550	COG0072	phenylalanine-tRNA ligase activity
BPUM_RS12555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BPUM_RS12560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BPUM_RS12570	COG1966	Carbon starvation protein
BPUM_RS12575	COG1363	Peptidase, m42
BPUM_RS12585	COG3326	Membrane
BPUM_RS12590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BPUM_RS12595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BPUM_RS12600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BPUM_RS12605	COG1346	cytolysis
BPUM_RS12615	COG3279	Response regulator of the LytR AlgR family
BPUM_RS12620	COG3275	phosphorelay sensor kinase activity
BPUM_RS12625	COG1011	Hydrolase
BPUM_RS12635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BPUM_RS12645	COG0398	Pfam SNARE associated Golgi protein
BPUM_RS12650	COG1484	DNA-dependent DNA replication
BPUM_RS12655	COG3611	Membrane attachment protein
BPUM_RS12670	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BPUM_RS12675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BPUM_RS12680	COG0237	dephospho-CoA kinase activity
BPUM_RS12685	COG1971	Probably functions as a manganese efflux pump
BPUM_RS12690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BPUM_RS12695	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BPUM_RS12695	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BPUM_RS12700	COG5002	protein histidine kinase activity
BPUM_RS12705	COG0745	RESPONSE REGULATOR receiver
BPUM_RS12710	COG0039	L-malate dehydrogenase activity
BPUM_RS12715	COG0538	isocitrate dehydrogenase activity
BPUM_RS12720	COG0372	Belongs to the citrate synthase family
BPUM_RS12725	COG2707	UPF0756 membrane protein
BPUM_RS12730	COG0628	permease
BPUM_RS12735	COG3030	protein affecting phage T7 exclusion by the F plasmid
BPUM_RS12745	COG0205	6-phosphofructokinase activity
BPUM_RS12750	COG0825	malonyl-CoA metabolic process
BPUM_RS12755	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BPUM_RS12760	COG0281	malic enzyme
BPUM_RS12765	COG0587	DNA-directed DNA polymerase activity
BPUM_RS12785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BPUM_RS12795	COG4109	DRTGG domain
BPUM_RS12800	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BPUM_RS12805	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS12815	COG0165	Argininosuccinate lyase
BPUM_RS12820	COG0137	argininosuccinate synthase activity
BPUM_RS12830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BPUM_RS12835	COG0827	DNA restriction-modification system
BPUM_RS12840	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BPUM_RS12845	COG3874	Sporulation protein YtfJ
BPUM_RS12855	COG1714	RDD family
BPUM_RS12860	COG0616	signal peptide processing
BPUM_RS12865	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BPUM_RS12875	COG3239	Fatty acid desaturase
BPUM_RS12880	COG4585	Histidine kinase
BPUM_RS12885	COG2197	response regulator
BPUM_RS12890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS12895	COG0745	RESPONSE REGULATOR receiver
BPUM_RS12900	COG2205	protein histidine kinase activity
BPUM_RS12905	COG1136	(ABC) transporter
BPUM_RS12910	COG0577	efflux transmembrane transporter activity
BPUM_RS12915	COG0402	S-adenosylhomocysteine deaminase activity
BPUM_RS12920	COG2249	NAD(P)H dehydrogenase (quinone) activity
BPUM_RS12930	COG1279	arginine transmembrane transporter activity
BPUM_RS12935	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BPUM_RS12945	COG0301	tRNA thio-modification
BPUM_RS12955	COG1114	Component of the transport system for branched-chain amino acids
BPUM_RS12960	COG1114	Component of the transport system for branched-chain amino acids
BPUM_RS12965	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BPUM_RS12970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BPUM_RS12975	COG1309	transcriptional regulator
BPUM_RS12980	COG1956	GAF domain-containing protein
BPUM_RS12985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BPUM_RS12995	COG1335	isochorismatase
BPUM_RS13000	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BPUM_RS13010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BPUM_RS13015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BPUM_RS13020	COG0454	-acetyltransferase
BPUM_RS13025	COG0517	IMP dehydrogenase activity
BPUM_RS13030	COG0123	including yeast histone deacetylase and acetoin utilization protein
BPUM_RS13035	COG1609	Transcriptional regulator
BPUM_RS13040	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BPUM_RS13040	COG1605	Chorismate mutase
BPUM_RS13045	COG3118	belongs to the thioredoxin family
BPUM_RS13050	COG4980	gas vesicle protein
BPUM_RS13055	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BPUM_RS13060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BPUM_RS13070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BPUM_RS13075	COG4848	Belongs to the UPF0354 family
BPUM_RS13080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS13095	COG1363	Peptidase, m42
BPUM_RS13100	COG5584	Small secreted protein
BPUM_RS13105	COG0281	malic enzyme
BPUM_RS13110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BPUM_RS13115	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BPUM_RS13125	COG0510	thiamine kinase activity
BPUM_RS13130	COG1597	lipid kinase activity
BPUM_RS13140	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BPUM_RS13145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BPUM_RS13150	COG3340	Belongs to the peptidase S51 family
BPUM_RS13155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BPUM_RS13160	COG2252	PERMEase
BPUM_RS13165	COG1349	DNA-binding transcription factor activity
BPUM_RS13170	COG1187	pseudouridine synthase activity
BPUM_RS13175	COG2244	polysaccharide biosynthetic process
BPUM_RS13180	COG2081	HI0933 family
BPUM_RS13190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BPUM_RS13195	COG3196	Protein conserved in bacteria
BPUM_RS13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BPUM_RS13210	COG5578	integral membrane protein
BPUM_RS13215	COG0673	inositol 2-dehydrogenase activity
BPUM_RS13220	COG1653	transport
BPUM_RS13225	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BPUM_RS13230	COG4209	transmembrane transport
BPUM_RS13235	COG2207	Transcriptional regulator
BPUM_RS13240	COG1733	regulation of RNA biosynthetic process
BPUM_RS13245	COG2814	Major facilitator Superfamily
BPUM_RS13250	COG0656	L-ascorbic acid biosynthetic process
BPUM_RS13255	COG1653	transport
BPUM_RS13260	COG0395	ABC-type sugar transport system, permease component
BPUM_RS13265	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BPUM_RS13270	COG1073	alpha beta
BPUM_RS13275	COG0495	leucyl-tRNA aminoacylation
BPUM_RS13285	COG2202	Pas domain
BPUM_RS13285	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS13290	COG2433	Pfam Transposase IS66
BPUM_RS13295	COG0577	efflux transmembrane transporter activity
BPUM_RS13300	COG1136	(ABC) transporter
BPUM_RS13310	COG1131	(ABC) transporter
BPUM_RS13315	COG1725	Transcriptional regulator
BPUM_RS13330	COG1242	4 iron, 4 sulfur cluster binding
BPUM_RS13335	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BPUM_RS13345	COG2267	carboxylic ester hydrolase activity
BPUM_RS13350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BPUM_RS13355	COG0367	asparagine synthase
BPUM_RS13360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BPUM_RS13365	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BPUM_RS13375	COG1506	peptidase
BPUM_RS13380	COG1233	COG1233 Phytoene dehydrogenase and related
BPUM_RS13400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BPUM_RS13405	COG1116	anion transmembrane transporter activity
BPUM_RS13410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BPUM_RS13415	COG0494	nUDIX hydrolase
BPUM_RS13420	COG2310	stress, protein
BPUM_RS13435	COG4824	toxin secretion phage lysis holin
BPUM_RS13445	COG0783	Belongs to the Dps family
BPUM_RS13460	COG1854	S-ribosylhomocysteine lyase activity
BPUM_RS13465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BPUM_RS13470	COG0288	reversible hydration of carbon dioxide
BPUM_RS13475	COG3443	Belongs to the bacterial solute-binding protein 9 family
BPUM_RS13475	COG0803	Belongs to the bacterial solute-binding protein 9 family
BPUM_RS13490	COG1271	oxidase subunit
BPUM_RS13495	COG1294	oxidase, subunit
BPUM_RS13510	COG4948	Mandelate Racemase Muconate Lactonizing
BPUM_RS13515	COG0318	PFAM AMP-dependent synthetase and ligase
BPUM_RS13520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BPUM_RS13525	COG0596	Alpha beta hydrolase
BPUM_RS13530	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BPUM_RS13535	COG1169	isochorismate synthase
BPUM_RS13540	COG1575	Belongs to the MenA family. Type 1 subfamily
BPUM_RS13545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BPUM_RS13675	COG3859	Proton-coupled thiamine transporter YuaJ
BPUM_RS13685	COG1247	-acetyltransferase
BPUM_RS13690	COG3339	Conserved Protein
BPUM_RS13695	COG0772	Belongs to the SEDS family
BPUM_RS13705	COG2268	Band 7 protein
BPUM_RS13710	COG1585	Membrane protein implicated in regulation of membrane protease activity
BPUM_RS13715	COG2318	DinB family
BPUM_RS13720	COG1454	alcohol dehydrogenase
BPUM_RS13725	COG1012	belongs to the aldehyde dehydrogenase family
BPUM_RS13730	COG1510	regulation of RNA biosynthetic process
BPUM_RS13745	COG1876	peptidase activity
BPUM_RS13750	COG3594	Acyltransferase
BPUM_RS13795	COG3778	Protein conserved in bacteria
BPUM_RS13800	COG3299	homolog of phage Mu protein gp47
BPUM_RS13805	COG3628	GPW Gp25 family protein
BPUM_RS13815	COG4193	domain, Protein
BPUM_RS13820	COG1652	LysM domain
BPUM_RS13825	COG3953	SLT domain
BPUM_RS13825	COG5280	Phage tail tape measure protein TP901
BPUM_RS13825	COG3953	SLT domain
BPUM_RS13825	COG5280	Phage tail tape measure protein TP901
BPUM_RS13870	COG4653	Phage capsid family
BPUM_RS13875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BPUM_RS13880	COG5518	Phage portal protein
BPUM_RS13885	COG1783	phage Terminase large subunit
BPUM_RS13890	COG5484	DNA packaging
BPUM_RS13895	COG1595	DNA-templated transcription, initiation
BPUM_RS13920	COG1396	sequence-specific DNA binding
BPUM_RS13930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BPUM_RS13945	COG1968	undecaprenyl-diphosphatase activity
BPUM_RS13950	COG0628	permease
BPUM_RS13960	COG0673	inositol 2-dehydrogenase activity
BPUM_RS13965	COG0693	protein deglycase activity
BPUM_RS13970	COG0840	transmembrane signaling receptor activity
BPUM_RS13975	COG0840	transmembrane signaling receptor activity
BPUM_RS13980	COG0840	transmembrane signaling receptor activity
BPUM_RS13985	COG0840	transmembrane signaling receptor activity
BPUM_RS14000	COG2070	2-Nitropropane dioxygenase
BPUM_RS14005	COG0432	Pfam Uncharacterised protein family UPF0047
BPUM_RS14010	COG1253	flavin adenine dinucleotide binding
BPUM_RS14015	COG2738	Putative neutral zinc metallopeptidase
BPUM_RS14025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BPUM_RS14040	COG0166	Belongs to the GPI family
BPUM_RS14045	COG1979	alcohol dehydrogenase
BPUM_RS14050	COG1979	alcohol dehydrogenase
BPUM_RS14055	COG2155	Conserved Protein
BPUM_RS14060	COG1098	S1 RNA binding domain
BPUM_RS14065	COG0436	Aminotransferase
BPUM_RS14070	COG1522	sequence-specific DNA binding
BPUM_RS14075	COG2267	carboxylic ester hydrolase activity
BPUM_RS14085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BPUM_RS14090	COG2205	protein histidine kinase activity
BPUM_RS14105	COG5018	Exonuclease
BPUM_RS14110	COG2814	Major facilitator Superfamily
BPUM_RS14115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BPUM_RS14120	COG3011	Protein conserved in bacteria
BPUM_RS14130	COG3290	protein histidine kinase activity
BPUM_RS14135	COG4565	transcriptional regulatory protein
BPUM_RS14140	COG1744	ABC transporter substrate-binding protein PnrA-like
BPUM_RS14145	COG3845	ABC transporter
BPUM_RS14150	COG4603	Belongs to the binding-protein-dependent transport system permease family
BPUM_RS14155	COG1079	Belongs to the binding-protein-dependent transport system permease family
BPUM_RS14160	COG3493	citrate carrier protein
BPUM_RS14170	COG2111	Na H antiporter
BPUM_RS14170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BPUM_RS14175	COG2111	Na H antiporter
BPUM_RS14180	COG1006	Multisubunit Na H antiporter MnhC subunit
BPUM_RS14185	COG0651	ATP synthesis coupled electron transport
BPUM_RS14190	COG1863	multisubunit Na H antiporter MnhE subunit
BPUM_RS14195	COG2212	antiporter activity
BPUM_RS14200	COG1320	monovalent cation:proton antiporter activity
BPUM_RS14205	COG2050	protein possibly involved in aromatic compounds catabolism
BPUM_RS14210	COG2197	response regulator
BPUM_RS14215	COG4585	Histidine kinase
BPUM_RS14225	COG0142	geranyltranstransferase activity
BPUM_RS14240	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BPUM_RS14245	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BPUM_RS14250	COG1335	isochorismatase
BPUM_RS14255	COG5506	Protein of unknown function (DUF1694)
BPUM_RS14275	COG0628	permease
BPUM_RS14290	COG1418	mRNA catabolic process
BPUM_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS14305	COG1511	domain protein
BPUM_RS14310	COG0433	COG0433 Predicted ATPase
BPUM_RS14310	COG1674	ftsk spoiiie
BPUM_RS14315	COG4499	WXG100 protein secretion system (Wss), protein YukC
BPUM_RS14320	COG5417	Belongs to the EsaB family
BPUM_RS14325	COG4842	Belongs to the WXG100 family
BPUM_RS14330	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BPUM_RS14330	COG2508	Transcriptional regulator
BPUM_RS14335	COG0686	Belongs to the AlaDH PNT family
BPUM_RS14340	COG1268	BioY protein
BPUM_RS14345	COG4326	sporulation control protein
BPUM_RS14350	COG2056	Na+-H+ antiporter family
BPUM_RS14355	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BPUM_RS14360	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BPUM_RS14365	COG3584	3D domain protein
BPUM_RS14375	COG1252	NADH dehydrogenase
BPUM_RS14380	COG0492	ferredoxin-NADP+ reductase activity
BPUM_RS14395	COG0316	Belongs to the HesB IscA family
BPUM_RS14400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BPUM_RS14405	COG4844	belongs to the
BPUM_RS14410	COG1252	NADH dehydrogenase
BPUM_RS14420	COG4837	Protein of unknown function (DUF1462)
BPUM_RS14425	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BPUM_RS14430	COG1506	peptidase
BPUM_RS14430	COG0823	Involved in the tonB-independent uptake of proteins
BPUM_RS14430	COG4946	Tricorn protease homolog
BPUM_RS14435	COG0083	homoserine kinase activity
BPUM_RS14440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BPUM_RS14445	COG0460	homoserine dehydrogenase
BPUM_RS14450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPUM_RS14455	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BPUM_RS14460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BPUM_RS14465	COG0647	UMP catabolic process
BPUM_RS14470	COG2445	Protein of unknown function DUF86
BPUM_RS14475	COG4470	Protein conserved in bacteria
BPUM_RS14485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BPUM_RS14490	COG0739	heme binding
BPUM_RS14505	COG3377	Domain of unknown function (DUF1805)
BPUM_RS14510	COG0737	Belongs to the 5'-nucleotidase family
BPUM_RS14515	COG1801	Protein of unknown function DUF72
BPUM_RS14520	COG2508	Transcriptional regulator
BPUM_RS14525	COG2140	Oxalate decarboxylase
BPUM_RS14530	COG2814	Major facilitator Superfamily
BPUM_RS14535	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BPUM_RS14540	COG2356	endonuclease I
BPUM_RS14550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS14555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS14560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS14580	COG0642	Histidine kinase
BPUM_RS14580	COG5002	protein histidine kinase activity
BPUM_RS14585	COG0745	RESPONSE REGULATOR receiver
BPUM_RS14590	COG2311	Membrane
BPUM_RS14610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BPUM_RS14615	COG0719	Fe-S assembly protein
BPUM_RS14620	COG0822	iron-sulfur transferase activity
BPUM_RS14625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BPUM_RS14630	COG0719	Fe-S assembly protein
BPUM_RS14635	COG0396	ATPase activity
BPUM_RS14640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BPUM_RS14645	COG1464	Belongs to the NlpA lipoprotein family
BPUM_RS14650	COG2011	ABC-type metal ion transport system permease component
BPUM_RS14655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BPUM_RS14665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS14670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BPUM_RS14680	COG0509	glycine decarboxylation via glycine cleavage system
BPUM_RS14685	COG1393	Belongs to the ArsC family
BPUM_RS14690	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS14695	COG0183	Belongs to the thiolase family
BPUM_RS14700	COG1024	Enoyl-CoA hydratase
BPUM_RS14700	COG1250	3-hydroxyacyl-CoA dehydrogenase
BPUM_RS14710	COG5577	PFAM Coat F domain
BPUM_RS14730	COG1120	ATPase activity
BPUM_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS14745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BPUM_RS14750	COG0745	RESPONSE REGULATOR receiver
BPUM_RS14755	COG2770	Histidine kinase
BPUM_RS14755	COG2205	protein histidine kinase activity
BPUM_RS14760	COG1309	transcriptional regulator
BPUM_RS14765	COG0114	fumarate hydratase activity
BPUM_RS14770	COG0697	spore germination
BPUM_RS14775	COG0814	amino acid
BPUM_RS14790	COG2197	response regulator
BPUM_RS14795	COG4585	Histidine kinase
BPUM_RS14800	COG4758	membrane
BPUM_RS14810	COG1842	Phage shock protein A
BPUM_RS14815	COG4758	membrane
BPUM_RS14820	COG2096	Adenosyltransferase
BPUM_RS14825	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS14830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BPUM_RS14835	COG3395	kinase activity
BPUM_RS14840	COG2204	response regulator
BPUM_RS14855	COG1454	alcohol dehydrogenase
BPUM_RS14860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BPUM_RS14865	COG1120	ATPase activity
BPUM_RS14870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS14875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS14885	COG2721	sulfolactate sulfo-lyase activity
BPUM_RS14890	COG0246	Mannitol dehydrogenase
BPUM_RS14895	COG1609	Transcriptional regulator
BPUM_RS14900	COG1904	glucuronate isomerase
BPUM_RS14905	COG2205	protein histidine kinase activity
BPUM_RS14910	COG0745	RESPONSE REGULATOR receiver
BPUM_RS14915	COG1120	ATPase activity
BPUM_RS14920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS14925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS14930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS14935	COG0531	amino acid
BPUM_RS14955	COG1988	membrane-bound metal-dependent
BPUM_RS14960	COG1368	sulfuric ester hydrolase activity
BPUM_RS14965	COG0725	ABC transporter, periplasmic molybdate-binding protein
BPUM_RS14970	COG4149	molybdate abc transporter
BPUM_RS14975	COG0656	L-ascorbic acid biosynthetic process
BPUM_RS14980	COG1940	carbohydrate kinase activity
BPUM_RS14985	COG0025	NhaP-type Na H and K H
BPUM_RS14990	COG2860	membrane
BPUM_RS14995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BPUM_RS15000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BPUM_RS15005	COG2217	Heavy metal translocating P-type atpase
BPUM_RS15010	COG1121	(ABC) transporter
BPUM_RS15015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BPUM_RS15020	COG0803	Belongs to the bacterial solute-binding protein 9 family
BPUM_RS15030	COG3226	Transcriptional regulator
BPUM_RS15035	COG0784	Response regulator, receiver
BPUM_RS15040	COG4191	Histidine kinase
BPUM_RS15045	COG1027	Aspartate ammonia-lyase
BPUM_RS15055	COG2217	Heavy metal translocating P-type atpase
BPUM_RS15060	COG2608	mercury ion transmembrane transporter activity
BPUM_RS15065	COG1937	Protein conserved in bacteria
BPUM_RS15100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BPUM_RS15105	COG0557	exoribonuclease II activity
BPUM_RS15110	COG1647	Serine aminopeptidase, S33
BPUM_RS15115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BPUM_RS15120	COG2002	toxin-antitoxin pair type II binding
BPUM_RS15125	COG1476	TRANSCRIPTIONal
BPUM_RS15130	COG1396	sequence-specific DNA binding
BPUM_RS15135	COG1396	sequence-specific DNA binding
BPUM_RS15140	COG1733	regulation of RNA biosynthetic process
BPUM_RS15145	COG1174	glycine betaine transport
BPUM_RS15150	COG1732	Glycine betaine
BPUM_RS15155	COG1174	glycine betaine transport
BPUM_RS15160	COG0517	IMP dehydrogenase activity
BPUM_RS15160	COG1125	glycine betaine transport
BPUM_RS15165	COG1510	regulation of RNA biosynthetic process
BPUM_RS15170	COG2095	MarC family integral membrane protein
BPUM_RS15180	COG0456	acetyltransferase
BPUM_RS15200	COG1131	(ABC) transporter
BPUM_RS15210	COG0148	phosphopyruvate hydratase activity
BPUM_RS15215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BPUM_RS15220	COG0149	triose-phosphate isomerase activity
BPUM_RS15225	COG0126	phosphoglycerate kinase activity
BPUM_RS15230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BPUM_RS15235	COG2390	Transcriptional regulator
BPUM_RS15240	COG0833	amino acid
BPUM_RS15245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BPUM_RS15250	COG3829	transcription factor binding
BPUM_RS15255	COG2186	Transcriptional regulator
BPUM_RS15260	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BPUM_RS15270	COG0534	Mate efflux family protein
BPUM_RS15275	COG4608	Belongs to the ABC transporter superfamily
BPUM_RS15280	COG0444	Belongs to the ABC transporter superfamily
BPUM_RS15285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BPUM_RS15290	COG0601	transmembrane transport
BPUM_RS15295	COG0747	negative chemotaxis
BPUM_RS15300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BPUM_RS15305	COG0110	maltose O-acetyltransferase activity
BPUM_RS15310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BPUM_RS15315	COG2244	polysaccharide biosynthetic process
BPUM_RS15320	COG5039	Polysaccharide pyruvyl transferase
BPUM_RS15325	COG1216	Glycosyl transferase, family 2
BPUM_RS15335	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS15340	COG1215	transferase activity, transferring glycosyl groups
BPUM_RS15345	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS15350	COG1086	Polysaccharide biosynthesis protein
BPUM_RS15355	COG0489	protein tyrosine kinase activity
BPUM_RS15360	COG3944	biosynthesis protein
BPUM_RS15365	COG1396	sequence-specific DNA binding
BPUM_RS15375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS15380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS15385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BPUM_RS15390	COG0726	polysaccharide deacetylase
BPUM_RS15395	COG0488	(ABC) transporter
BPUM_RS15400	COG1124	(ABC) transporter
BPUM_RS15415	COG0601	transmembrane transport
BPUM_RS15420	COG0747	negative chemotaxis
BPUM_RS15425	COG1819	glycosyl
BPUM_RS15450	COG0740	serine-type endopeptidase activity
BPUM_RS15455	COG1611	Belongs to the LOG family
BPUM_RS15460	COG1694	Mazg nucleotide pyrophosphohydrolase
BPUM_RS15465	COG0659	secondary active sulfate transmembrane transporter activity
BPUM_RS15470	COG0288	reversible hydration of carbon dioxide
BPUM_RS15475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BPUM_RS15485	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BPUM_RS15490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS15495	COG1481	regulation of sporulation
BPUM_RS15500	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BPUM_RS15505	COG1660	Displays ATPase and GTPase activities
BPUM_RS15510	COG1051	belongs to the nudix hydrolase family
BPUM_RS15515	COG0492	ferredoxin-NADP+ reductase activity
BPUM_RS15520	COG0791	NLP P60 protein
BPUM_RS15520	COG3883	PFAM NLP P60 protein
BPUM_RS15525	COG0457	Tetratricopeptide repeat
BPUM_RS15530	COG0140	phosphoribosyl-ATP diphosphatase activity
BPUM_RS15530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BPUM_RS15535	COG0107	imidazoleglycerol-phosphate synthase activity
BPUM_RS15540	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BPUM_RS15545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BPUM_RS15550	COG0131	Imidazoleglycerol-phosphate dehydratase
BPUM_RS15555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BPUM_RS15560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BPUM_RS15565	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BPUM_RS15570	COG4990	cell redox homeostasis
BPUM_RS15580	COG2910	NAD(P)H-binding
BPUM_RS15585	COG1959	2 iron, 2 sulfur cluster binding
BPUM_RS15590	COG0110	maltose O-acetyltransferase activity
BPUM_RS15595	COG0546	phosphoglycolate phosphatase activity
BPUM_RS15600	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BPUM_RS15605	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BPUM_RS15610	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BPUM_RS15615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BPUM_RS15620	COG0363	glucosamine-6-phosphate deaminase activity
BPUM_RS15625	COG2188	Transcriptional regulator
BPUM_RS15630	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BPUM_RS15635	COG1950	PFAM Membrane protein of
BPUM_RS15640	COG1983	PspC domain protein
BPUM_RS15645	COG3595	metallopeptidase activity
BPUM_RS15660	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BPUM_RS15670	COG4897	Protein conserved in bacteria
BPUM_RS15675	COG0574	Belongs to the PEP-utilizing enzyme family
BPUM_RS15675	COG3848	Pyruvate phosphate dikinase
BPUM_RS15680	COG1309	transcriptional regulator
BPUM_RS15685	COG2814	Major facilitator Superfamily
BPUM_RS15695	COG0745	RESPONSE REGULATOR receiver
BPUM_RS15700	COG5002	protein histidine kinase activity
BPUM_RS15705	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BPUM_RS15710	COG0463	Glycosyl transferase, family 2
BPUM_RS15715	COG1113	amino acid transport
BPUM_RS15720	COG0778	Nitroreductase
BPUM_RS15725	COG1733	regulation of RNA biosynthetic process
BPUM_RS15730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BPUM_RS15740	COG0793	Belongs to the peptidase S41A family
BPUM_RS15740	COG3409	Peptidoglycan-binding domain 1 protein
BPUM_RS15745	COG0730	response to heat
BPUM_RS15750	COG3883	PFAM NLP P60 protein
BPUM_RS15750	COG0791	NLP P60 protein
BPUM_RS15755	COG2177	Part of the ABC transporter FtsEX involved in
BPUM_RS15760	COG2884	Cell division ATP-binding protein ftsE
BPUM_RS15765	COG2010	Cytochrome c
BPUM_RS15770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BPUM_RS15785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BPUM_RS15790	COG0653	protein targeting
BPUM_RS15795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BPUM_RS15800	COG0840	transmembrane signaling receptor activity
BPUM_RS15815	COG1516	flagellar protein fliS
BPUM_RS15820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BPUM_RS15825	COG1334	flagellar protein FlaG
BPUM_RS15830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BPUM_RS15835	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BPUM_RS15845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BPUM_RS15850	COG4786	Flagellar basal body rod
BPUM_RS15850	COG1256	bacterial-type flagellum assembly
BPUM_RS15855	COG3418	PFAM FlgN family protein
BPUM_RS15870	COG1040	competence protein
BPUM_RS15880	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BPUM_RS15885	COG1307	EDD domain protein, DegV family
BPUM_RS15890	COG2197	response regulator
BPUM_RS15895	COG4585	Histidine kinase
BPUM_RS15900	COG1739	Uncharacterized protein family UPF0029
BPUM_RS15905	COG1316	TRANSCRIPTIONal
BPUM_RS15910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BPUM_RS15915	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS15920	COG1215	transferase activity, transferring glycosyl groups
BPUM_RS15925	COG3206	protein involved in exopolysaccharide biosynthesis
BPUM_RS15930	COG3307	-O-antigen
BPUM_RS15935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BPUM_RS15940	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BPUM_RS15945	COG0297	glycogen (starch) synthase activity
BPUM_RS15945	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS15950	COG2244	polysaccharide biosynthetic process
BPUM_RS15965	COG0860	N-Acetylmuramoyl-L-alanine amidase
BPUM_RS15965	COG2247	cell wall binding repeat
BPUM_RS15970	COG2247	cell wall binding repeat
BPUM_RS15970	COG2385	sporulation resulting in formation of a cellular spore
BPUM_RS15980	COG1316	TRANSCRIPTIONal
BPUM_RS15985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BPUM_RS15990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BPUM_RS15995	COG1134	teichoic acid transport
BPUM_RS16000	COG1682	transport, permease protein
BPUM_RS16005	COG1216	Glycosyl transferase, family 2
BPUM_RS16015	COG1181	Belongs to the D-alanine--D-alanine ligase family
BPUM_RS16020	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BPUM_RS16030	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BPUM_RS16035	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BPUM_RS16040	COG0438	transferase activity, transferring glycosyl groups
BPUM_RS16045	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BPUM_RS16050	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BPUM_RS16055	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BPUM_RS16060	COG4193	domain, Protein
BPUM_RS16065	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BPUM_RS16065	COG0463	Glycosyl transferase, family 2
BPUM_RS16070	COG1482	cell wall glycoprotein biosynthetic process
BPUM_RS16080	COG1175	transmembrane transport
BPUM_RS16085	COG1653	transport
BPUM_RS16090	COG2197	response regulator
BPUM_RS16095	COG2972	Histidine kinase
BPUM_RS16105	COG0454	-acetyltransferase
BPUM_RS16110	COG0800	Aldolase
BPUM_RS16115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPUM_RS16120	COG1609	Transcriptional regulator
BPUM_RS16125	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BPUM_RS16130	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS16135	COG0697	spore germination
BPUM_RS16140	COG0814	amino acid
BPUM_RS16155	COG2814	Major facilitator Superfamily
BPUM_RS16160	COG1316	TRANSCRIPTIONal
BPUM_RS16165	COG0561	phosphatase activity
BPUM_RS16170	COG0791	NLP P60 protein
BPUM_RS16175	COG2843	Capsule synthesis protein
BPUM_RS16185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BPUM_RS16190	COG0697	spore germination
BPUM_RS16205	COG1609	Transcriptional regulator
BPUM_RS16210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BPUM_RS16215	COG1869	D-ribose catabolic process
BPUM_RS16220	COG1129	ABC transporter
BPUM_RS16225	COG1172	Belongs to the binding-protein-dependent transport system permease family
BPUM_RS16230	COG1879	ABC-type sugar transport system periplasmic component
BPUM_RS16235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BPUM_RS16240	COG0583	DNA-binding transcription factor activity
BPUM_RS16245	COG0028	Belongs to the TPP enzyme family
BPUM_RS16250	COG3527	Alpha-acetolactate decarboxylase
BPUM_RS16255	COG1522	sequence-specific DNA binding
BPUM_RS16260	COG2059	Chromate
BPUM_RS16265	COG2059	Chromate
BPUM_RS16270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BPUM_RS16275	COG4715	Zinc finger, swim domain protein
BPUM_RS16280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BPUM_RS16285	COG2202	Pas domain
BPUM_RS16285	COG1366	Belongs to the anti-sigma-factor antagonist family
BPUM_RS16290	COG0561	phosphatase activity
BPUM_RS16305	COG1970	mechanosensitive ion channel activity
BPUM_RS16310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BPUM_RS16315	COG0457	Tetratricopeptide repeat
BPUM_RS16320	COG4786	Flagellar basal body rod
BPUM_RS16325	COG4786	Flagellar basal body rod
BPUM_RS16330	COG1077	Cell shape determining protein MreB Mrl
BPUM_RS16335	COG1609	Transcriptional regulator
BPUM_RS16340	COG1846	Transcriptional regulator
BPUM_RS16345	COG2814	Major facilitator Superfamily
BPUM_RS16350	COG0671	phosphoesterase, PA-phosphatase related
BPUM_RS16355	COG0477	Major facilitator Superfamily
BPUM_RS16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS16365	COG0765	amino acid transport
BPUM_RS16370	COG1126	abc transporter atp-binding protein
BPUM_RS16375	COG0004	ammonium transporteR
BPUM_RS16380	COG0347	Belongs to the P(II) protein family
BPUM_RS16385	COG0739	heme binding
BPUM_RS16390	COG1247	-acetyltransferase
BPUM_RS16425	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BPUM_RS16430	COG0523	cobalamin synthesis protein
BPUM_RS16435	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BPUM_RS16445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BPUM_RS16450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BPUM_RS16455	COG2223	nitrite transmembrane transporter activity
BPUM_RS16460	COG0243	molybdopterin cofactor binding
BPUM_RS16465	COG2304	oxidoreductase activity
BPUM_RS16470	COG2304	oxidoreductase activity
BPUM_RS16475	COG2385	sporulation resulting in formation of a cellular spore
BPUM_RS16480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BPUM_RS16490	COG4836	Membrane
BPUM_RS16500	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BPUM_RS16505	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BPUM_RS16510	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BPUM_RS16515	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BPUM_RS16520	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPUM_RS16525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BPUM_RS16530	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BPUM_RS16535	COG0356	it plays a direct role in the translocation of protons across the membrane
BPUM_RS16545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BPUM_RS16550	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BPUM_RS16555	COG4475	Protein of unknown function (DUF436)
BPUM_RS16560	COG0698	ribose 5-phosphate isomerase
BPUM_RS16565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BPUM_RS16570	COG1971	Probably functions as a manganese efflux pump
BPUM_RS16575	COG0009	L-threonylcarbamoyladenylate synthase
BPUM_RS16580	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BPUM_RS16595	COG2890	protein-(glutamine-N5) methyltransferase activity
BPUM_RS16600	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BPUM_RS16605	COG0789	Transcriptional regulator
BPUM_RS16610	COG0679	Auxin Efflux Carrier
BPUM_RS16615	COG0281	malic enzyme
BPUM_RS16620	COG1435	thymidine kinase activity
BPUM_RS16625	COG0254	rRNA binding
BPUM_RS16635	COG1494	fructose-1,6-bisphosphatase
BPUM_RS16640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BPUM_RS16645	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BPUM_RS16650	COG0191	fructose-bisphosphate aldolase activity
BPUM_RS16655	COG2204	response regulator
BPUM_RS16660	COG4821	SIS domain
BPUM_RS16665	COG0504	CTP synthase activity
BPUM_RS16670	COG3343	RNA polymerase activity
BPUM_RS16680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BPUM_RS16705	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS16710	COG1960	acyl-CoA dehydrogenase activity
BPUM_RS16715	COG1250	3-hydroxyacyl-CoA dehydrogenase
BPUM_RS16720	COG0183	Belongs to the thiolase family
BPUM_RS16725	COG0247	lactate metabolic process
BPUM_RS16725	COG2181	nitrate reductase activity
BPUM_RS16730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPUM_RS16735	COG4294	response to UV
BPUM_RS16745	COG1619	proteins homologs of microcin C7 resistance protein MccF
BPUM_RS16750	COG1132	(ABC) transporter
BPUM_RS16755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BPUM_RS16760	COG1619	proteins homologs of microcin C7 resistance protein MccF
BPUM_RS16770	COG0018	arginyl-trna synthetase
BPUM_RS16775	COG4506	Protein conserved in bacteria
BPUM_RS16785	COG0010	Belongs to the arginase family
BPUM_RS16790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BPUM_RS16795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BPUM_RS16805	COG1994	Peptidase M50
BPUM_RS16810	COG1942	4-Oxalocrotonate Tautomerase
BPUM_RS16820	COG3465	dGTPase activity
BPUM_RS16825	COG1078	dGTPase activity
BPUM_RS16830	COG4844	belongs to the
BPUM_RS16885	COG5444	nuclease activity
BPUM_RS16915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BPUM_RS16925	COG0280	phosphate acetyltransferase
BPUM_RS16935	COG2814	Major facilitator Superfamily
BPUM_RS16940	COG1522	sequence-specific DNA binding
BPUM_RS16945	COG2814	Major facilitator Superfamily
BPUM_RS16950	COG0077	Prephenate dehydratase
BPUM_RS16955	COG1917	Cupin 2, conserved barrel domain protein
BPUM_RS16960	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS16965	COG0151	Belongs to the GarS family
BPUM_RS16970	COG0436	Aminotransferase
BPUM_RS16975	COG1028	Short-chain dehydrogenase reductase Sdr
BPUM_RS16980	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BPUM_RS16985	COG1091	dTDP-4-dehydrorhamnose reductase activity
BPUM_RS16990	COG1088	dTDP-glucose 4,6-dehydratase activity
BPUM_RS16995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BPUM_RS17000	COG3980	spore coat polysaccharide biosynthesis protein
BPUM_RS17005	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
BPUM_RS17010	COG2089	acid synthase
BPUM_RS17015	COG0456	acetyltransferase
BPUM_RS17020	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BPUM_RS17025	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BPUM_RS17030	COG0463	Glycosyl transferase, family 2
BPUM_RS17050	COG2363	Small membrane protein
BPUM_RS17055	COG2233	PERMEase
BPUM_RS17070	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BPUM_RS17075	COG1216	Glycosyl transferase, family 2
BPUM_RS17085	COG0351	phosphomethylpyrimidine kinase
BPUM_RS17100	COG1621	beta-fructofuranosidase activity
BPUM_RS17105	COG1263	PTS System
BPUM_RS17105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS17110	COG3711	transcriptional antiterminator
BPUM_RS17120	COG1404	Belongs to the peptidase S8 family
BPUM_RS17130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BPUM_RS17135	COG0778	Nitroreductase
BPUM_RS17140	COG0772	Belongs to the SEDS family
BPUM_RS17150	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BPUM_RS17155	COG1845	cytochrome c oxidase, subunit III
BPUM_RS17160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BPUM_RS17165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BPUM_RS17175	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
BPUM_RS17180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BPUM_RS17185	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BPUM_RS17200	COG2246	polysaccharide biosynthetic process
BPUM_RS17225	COG0457	Tetratricopeptide repeat
BPUM_RS17240	COG3162	membrane
BPUM_RS17245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BPUM_RS17260	COG0352	thiamine-phosphate diphosphorylase activity
BPUM_RS17265	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BPUM_RS17270	COG0583	DNA-binding transcription factor activity
BPUM_RS17275	COG1380	Effector of murein hydrolase LrgA
BPUM_RS17280	COG1346	cytolysis
BPUM_RS17285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BPUM_RS17290	COG0346	lactoylglutathione lyase activity
BPUM_RS17295	COG1126	abc transporter atp-binding protein
BPUM_RS17300	COG0765	amino acid transport
BPUM_RS17305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BPUM_RS17310	COG0457	Tetratricopeptide repeat
BPUM_RS17315	COG2357	RelA SpoT domain protein
BPUM_RS17320	COG1172	Belongs to the binding-protein-dependent transport system permease family
BPUM_RS17325	COG1129	ABC transporter
BPUM_RS17335	COG3420	alginic acid biosynthetic process
BPUM_RS17340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BPUM_RS17355	COG1486	melibiose metabolic process
BPUM_RS17360	COG1447	Phosphotransferase system cellobiose-specific component IIA
BPUM_RS17365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS17370	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS17375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS17375	COG3711	transcriptional antiterminator
BPUM_RS17390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BPUM_RS17405	COG1595	DNA-templated transcription, initiation
BPUM_RS17415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BPUM_RS17420	COG4988	ABC transporter
BPUM_RS17425	COG1294	oxidase, subunit
BPUM_RS17430	COG1271	oxidase subunit
BPUM_RS17450	COG4509	Sortase family
BPUM_RS17475	COG5386	Cell surface protein
BPUM_RS17480	COG5386	Cell surface protein
BPUM_RS17485	COG1733	regulation of RNA biosynthetic process
BPUM_RS17490	COG2514	catechol 2,3-dioxygenase activity
BPUM_RS17495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPUM_RS17495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BPUM_RS17500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BPUM_RS17500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BPUM_RS17510	COG0726	polysaccharide deacetylase
BPUM_RS17515	COG1447	Phosphotransferase system cellobiose-specific component IIA
BPUM_RS17520	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS17525	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS17535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BPUM_RS17540	COG3711	transcriptional antiterminator
BPUM_RS17540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BPUM_RS17565	COG1757	Na H antiporter
BPUM_RS17570	COG1027	Aspartate ammonia-lyase
BPUM_RS17575	COG0252	asparaginase activity
BPUM_RS17580	COG1396	sequence-specific DNA binding
BPUM_RS17605	COG4842	Belongs to the WXG100 family
BPUM_RS17610	COG2195	Cleaves the N-terminal amino acid of tripeptides
BPUM_RS17625	COG1737	Transcriptional regulator
BPUM_RS17630	COG2084	Dehydrogenase
BPUM_RS17640	COG2610	gluconate transmembrane transporter activity
BPUM_RS17645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BPUM_RS17655	COG1136	(ABC) transporter
BPUM_RS17660	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS17665	COG1263	PTS System
BPUM_RS17665	COG2190	(PTS) system
BPUM_RS17665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS17670	COG3711	transcriptional antiterminator
BPUM_RS17680	COG3878	Protein conserved in bacteria
BPUM_RS17690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPUM_RS17695	COG1122	ATPase activity
BPUM_RS17700	COG4721	ABC-type cobalt transport system, permease component
BPUM_RS17705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BPUM_RS17735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BPUM_RS17740	COG0778	Nitroreductase
BPUM_RS17745	COG1846	Transcriptional regulator
BPUM_RS17750	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BPUM_RS17755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BPUM_RS17760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BPUM_RS17765	COG2390	Transcriptional regulator
BPUM_RS17775	COG2755	lipolytic protein G-D-S-L family
BPUM_RS17775	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BPUM_RS17780	COG0477	Major facilitator Superfamily
BPUM_RS17800	COG0561	phosphatase activity
BPUM_RS17805	COG0789	Transcriptional regulator
BPUM_RS17810	COG0673	inositol 2-dehydrogenase activity
BPUM_RS17815	COG0840	transmembrane signaling receptor activity
BPUM_RS17820	COG1113	amino acid transport
BPUM_RS17825	COG4335	DNA alkylation repair
BPUM_RS17835	COG1070	Carbohydrate kinase
BPUM_RS17840	COG1737	Transcriptional regulator
BPUM_RS17880	COG0583	DNA-binding transcription factor activity
BPUM_RS17885	COG1609	Transcriptional regulator
BPUM_RS17890	COG2182	Extracellular solute-binding protein
BPUM_RS17895	COG1175	transmembrane transport
BPUM_RS17900	COG3833	ABC-type maltose transport systems, permease component
BPUM_RS17910	COG1874	Beta-galactosidase
BPUM_RS17915	COG2851	Citrate transporter
BPUM_RS17925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BPUM_RS17930	COG1131	(ABC) transporter
BPUM_RS17940	COG1131	(ABC) transporter
BPUM_RS17970	COG2824	Alkylphosphonate utilization operon protein PhnA
BPUM_RS17975	COG1929	Belongs to the glycerate kinase type-1 family
BPUM_RS17980	COG2610	gluconate transmembrane transporter activity
BPUM_RS17985	COG3835	regulator
BPUM_RS17990	COG1309	transcriptional regulator
BPUM_RS17995	COG2814	Major facilitator Superfamily
BPUM_RS18005	COG1136	(ABC) transporter
BPUM_RS18005	COG0577	efflux transmembrane transporter activity
BPUM_RS18035	COG0457	Tetratricopeptide repeat
BPUM_RS18040	COG3711	transcriptional antiterminator
BPUM_RS18045	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS18050	COG1263	PTS System
BPUM_RS18050	COG2190	(PTS) system
BPUM_RS18050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BPUM_RS18090	COG1113	amino acid transport
BPUM_RS18095	COG1609	Transcriptional regulator
BPUM_RS18100	COG2814	Major facilitator Superfamily
BPUM_RS18110	COG2814	Major facilitator Superfamily
BPUM_RS18130	COG2723	6-phospho-beta-galactosidase activity
BPUM_RS18135	COG2188	Transcriptional regulator
BPUM_RS18150	COG0384	phenazine biosynthesis protein PhzF
BPUM_RS18155	COG0583	DNA-binding transcription factor activity
BPUM_RS18200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BPUM_RS18205	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BPUM_RS18215	COG4720	Psort location CytoplasmicMembrane, score
BPUM_RS18235	COG0456	acetyltransferase
BPUM_RS18240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BPUM_RS18245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BPUM_RS18250	COG4853	Protein conserved in bacteria
BPUM_RS18255	COG4863	YycH protein
BPUM_RS18260	COG5002	protein histidine kinase activity
BPUM_RS18265	COG0745	RESPONSE REGULATOR receiver
BPUM_RS18290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BPUM_RS18300	COG2311	Membrane
BPUM_RS18305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BPUM_RS18310	COG1309	transcriptional regulator
BPUM_RS18315	COG2124	cytochrome p450
BPUM_RS18320	COG0346	lactoylglutathione lyase activity
BPUM_RS18325	COG0305	Participates in initiation and elongation during chromosome replication
BPUM_RS18340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS18340	COG2207	Transcriptional regulator
BPUM_RS18345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BPUM_RS18350	COG2819	hydrolase of the alpha beta superfamily
BPUM_RS18355	COG2807	transmembrane transport
BPUM_RS18360	COG0359	binds to the 23S rRNA
BPUM_RS18365	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BPUM_RS18375	COG1227	inorganic diphosphatase activity
BPUM_RS18385	COG1595	DNA-templated transcription, initiation
BPUM_RS18395	COG0753	catalase activity
BPUM_RS18400	COG0655	NAD(P)H dehydrogenase (quinone) activity
BPUM_RS18405	COG0400	carboxylic ester hydrolase activity
BPUM_RS18410	COG0346	lactoylglutathione lyase activity
BPUM_RS18415	COG1174	glycine betaine transport
BPUM_RS18420	COG1125	glycine betaine transport
BPUM_RS18420	COG0517	IMP dehydrogenase activity
BPUM_RS18425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BPUM_RS18430	COG0629	single-stranded DNA binding
BPUM_RS18435	COG0360	Binds together with S18 to 16S ribosomal RNA
BPUM_RS18440	COG0012	GTP binding
BPUM_RS18445	COG4481	Protein conserved in bacteria
BPUM_RS18460	COG3949	Membrane
BPUM_RS18470	COG1475	DNA binding
BPUM_RS18475	COG1192	Involved in chromosome partitioning
BPUM_RS18485	COG1475	DNA binding
BPUM_RS18490	COG0357	Ribosomal RNA small subunit methyltransferase G
BPUM_RS18495	COG0445	tRNA wobble uridine modification
BPUM_RS18500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BPUM_RS18505	COG1847	R3H domain protein
BPUM_RS18510	COG0706	membrane insertase activity
BPUM_RS18515	COG0594	ribonuclease P activity