locus-tag	class	description
M0696_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M0696_RS00010	COG0592	DNA-directed DNA polymerase activity
M0696_RS00015	COG2501	S4 domain
M0696_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
M0696_RS00030	COG0187	DNA topoisomerase II activity
M0696_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M0696_RS00070	COG0516	GMP reductase activity
M0696_RS00070	COG0517	IMP dehydrogenase activity
M0696_RS00075	COG1686	Belongs to the peptidase S11 family
M0696_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
M0696_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
M0696_RS00100	COG1428	Deoxynucleoside kinase
M0696_RS00105	COG1428	Deoxynucleoside kinase
M0696_RS00110	COG1388	LysM domain
M0696_RS00110	COG3858	chitin binding
M0696_RS00115	COG1335	isochorismatase
M0696_RS00120	COG0590	tRNA wobble adenosine to inosine editing
M0696_RS00130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M0696_RS00135	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
M0696_RS00140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M0696_RS00185	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
M0696_RS00190	COG3853	Toxic anion resistance protein (TelA)
M0696_RS00195	COG1982	Orn Lys Arg decarboxylase major
M0696_RS00200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M0696_RS00205	COG3870	Protein conserved in bacteria
M0696_RS00210	COG1728	Protein conserved in bacteria
M0696_RS00215	COG0470	DNA polymerase III
M0696_RS00220	COG1774	PSP1 C-terminal conserved region
M0696_RS00225	COG4467	Involved in initiation control of chromosome replication
M0696_RS00230	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M0696_RS00235	COG2827	Endonuclease containing a URI domain
M0696_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M0696_RS00245	COG2002	toxin-antitoxin pair type II binding
M0696_RS00250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_RS00250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_RS00255	COG0084	hydrolase, TatD family'
M0696_RS00260	COG3583	domain protein
M0696_RS00260	COG3584	3D domain protein
M0696_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M0696_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M0696_RS00280	COG4466	Protein conserved in bacteria
M0696_RS00290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
M0696_RS00295	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_RS00300	COG0251	oxidation-reduction process
M0696_RS00305	COG2088	sporulation resulting in formation of a cellular spore
M0696_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M0696_RS00315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M0696_RS00320	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
M0696_RS00325	COG0193	aminoacyl-tRNA hydrolase activity
M0696_RS00335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M0696_RS00340	COG2002	toxin-antitoxin pair type II binding
M0696_RS00345	COG2244	polysaccharide biosynthetic process
M0696_RS00350	COG3956	TIGRFAM MazG family protein
M0696_RS00355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M0696_RS00370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M0696_RS00375	COG1098	S1 RNA binding domain
M0696_RS00390	COG2208	phosphoserine phosphatase activity
M0696_RS00395	COG2304	oxidoreductase activity
M0696_RS00400	COG0515	serine threonine protein kinase
M0696_RS00405	COG0037	tRNA processing
M0696_RS00410	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
M0696_RS00415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M0696_RS00420	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
M0696_RS00425	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M0696_RS00430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M0696_RS00435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_RS00440	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M0696_RS00445	COG0512	Glutamine amidotransferase of anthranilate synthase
M0696_RS00450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M0696_RS00460	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
M0696_RS00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M0696_RS00470	COG1396	sequence-specific DNA binding
M0696_RS00475	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M0696_RS00480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M0696_RS00560	COG4463	regulation of RNA biosynthetic process
M0696_RS00565	COG3880	PFAM UvrB UvrC protein
M0696_RS00570	COG3869	Catalyzes the specific phosphorylation of arginine residues in
M0696_RS00575	COG0542	response to heat
M0696_RS00580	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
M0696_RS00585	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
M0696_RS00590	COG4956	integral membrane protein (PIN domain superfamily)
M0696_RS00595	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M0696_RS00600	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
M0696_RS00605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M0696_RS00610	COG1045	serine acetyltransferase
M0696_RS00615	COG0215	cysteine-tRNA ligase activity
M0696_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M0696_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M0696_RS00630	COG3688	RNA-binding protein containing a PIN domain
M0696_RS00635	COG1595	DNA-templated transcription, initiation
M0696_RS00645	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M0696_RS00650	COG0250	Participates in transcription elongation, termination and antitermination
M0696_RS00660	COG0081	regulation of translation
M0696_RS00665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M0696_RS00675	COG2813	Specifically methylates the guanine in position
M0696_RS00680	COG0085	RNA polymerase activity
M0696_RS00685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M0696_RS00690	COG1358	cellular component organization or biogenesis
M0696_RS00700	COG0049	tRNA binding
M0696_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
M0696_RS00710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M0696_RS00715	COG0596	Alpha beta hydrolase
M0696_RS00725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
M0696_RS00740	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M0696_RS00760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M0696_RS00770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M0696_RS00775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M0696_RS00785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M0696_RS00795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
M0696_RS00800	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
M0696_RS00805	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
M0696_RS00820	COG0200	Binds to the 23S rRNA
M0696_RS00825	COG0201	protein transport
M0696_RS00830	COG0563	adenylate kinase activity
M0696_RS00835	COG0024	Methionine aminopeptidase
M0696_RS00845	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M0696_RS00855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M0696_RS00860	COG0202	RNA polymerase activity
M0696_RS00865	COG0203	ribosomal protein L17
M0696_RS00870	COG1122	ATPase activity
M0696_RS00875	COG1122	ATPase activity
M0696_RS00880	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M0696_RS00885	COG0101	tRNA pseudouridine synthase activity
M0696_RS00890	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M0696_RS00900	COG2226	methyltransferase
M0696_RS00910	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS00915	COG0489	protein tyrosine kinase activity
M0696_RS00925	COG2194	sulfuric ester hydrolase activity
M0696_RS00930	COG0726	polysaccharide deacetylase
M0696_RS01010	COG0738	Major facilitator superfamily
M0696_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M0696_RS01020	COG0483	inositol monophosphate 1-phosphatase activity
M0696_RS01025	COG1063	alcohol dehydrogenase
M0696_RS01030	COG0659	secondary active sulfate transmembrane transporter activity
M0696_RS01035	COG0385	Bile acid
M0696_RS01040	COG2819	hydrolase of the alpha beta superfamily
M0696_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS01050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS01060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS01060	COG2207	Transcriptional regulator
M0696_RS01065	COG3876	Protein conserved in bacteria
M0696_RS01070	COG1472	Belongs to the glycosyl hydrolase 3 family
M0696_RS01075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_RS01080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS01080	COG1263	PTS System
M0696_RS01085	COG1737	Transcriptional regulator
M0696_RS01090	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
M0696_RS01095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS01100	COG1683	Conserved Protein
M0696_RS01130	COG1595	DNA-templated transcription, initiation
M0696_RS01135	COG5662	AntiSigma factor
M0696_RS01140	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M0696_RS01145	COG4856	YbbR-like protein
M0696_RS01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M0696_RS01165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M0696_RS01170	COG3002	Belongs to the UPF0753 family
M0696_RS01175	COG0288	reversible hydration of carbon dioxide
M0696_RS01185	COG5609	conserved protein (DUF2294)
M0696_RS01190	COG0640	Transcriptional regulator
M0696_RS01195	COG2814	Major facilitator Superfamily
M0696_RS01210	COG0596	Alpha beta hydrolase
M0696_RS01215	COG0745	RESPONSE REGULATOR receiver
M0696_RS01220	COG0642	Histidine kinase
M0696_RS01230	COG0515	serine threonine protein kinase
M0696_RS01245	COG1113	amino acid transport
M0696_RS01260	COG2602	Beta-lactamase
M0696_RS01265	COG2124	cytochrome p450
M0696_RS01275	COG1283	sodium-dependent phosphate transmembrane transporter activity
M0696_RS01280	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_RS01285	COG2271	Major facilitator Superfamily
M0696_RS01295	COG1846	Transcriptional regulator
M0696_RS01295	COG0456	acetyltransferase
M0696_RS01300	COG2271	Major facilitator Superfamily
M0696_RS01310	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS01315	COG0697	spore germination
M0696_RS01320	COG2207	Transcriptional regulator
M0696_RS01320	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS01325	COG1397	ADP-ribosylglycohydrolase
M0696_RS01335	COG5444	nuclease activity
M0696_RS01340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
M0696_RS01345	COG3591	Belongs to the peptidase S1B family
M0696_RS01355	COG0596	Alpha beta hydrolase
M0696_RS01360	COG1183	phosphatidylcholine synthase activity
M0696_RS01365	COG0586	Pfam SNARE associated Golgi protein
M0696_RS01370	COG0688	phosphatidylethanolamine metabolic process
M0696_RS01380	COG2312	Erythromycin esterase
M0696_RS01385	COG1054	Belongs to the UPF0176 family
M0696_RS01390	COG1301	dicarboxylic acid transport
M0696_RS01395	COG2190	(PTS) system
M0696_RS01395	COG1263	PTS System
M0696_RS01395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS01400	COG0363	glucosamine-6-phosphate deaminase activity
M0696_RS01405	COG2188	Transcriptional regulator
M0696_RS01415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_RS01420	COG0833	amino acid
M0696_RS01425	COG2040	homocysteine
M0696_RS01430	COG1115	amino acid carrier protein
M0696_RS01435	COG2066	Belongs to the glutaminase family
M0696_RS01440	COG4191	Histidine kinase
M0696_RS01445	COG0784	Response regulator, receiver
M0696_RS01450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M0696_RS01455	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS01460	COG2271	Major facilitator Superfamily
M0696_RS01465	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_RS01470	COG2186	Transcriptional regulator
M0696_RS01475	COG2721	sulfolactate sulfo-lyase activity
M0696_RS01480	COG3173	Aminoglycoside phosphotransferase
M0696_RS01490	COG0697	spore germination
M0696_RS01495	COG0745	RESPONSE REGULATOR receiver
M0696_RS01500	COG2205	protein histidine kinase activity
M0696_RS01505	COG1131	(ABC) transporter
M0696_RS01530	COG3773	Cell wall hydrolase
M0696_RS01545	COG3540	Alkaline phosphatase
M0696_RS01550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M0696_RS01555	COG0805	protein transport
M0696_RS01560	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
M0696_RS01565	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M0696_RS01570	COG0477	Major facilitator Superfamily
M0696_RS01575	COG1309	transcriptional regulator
M0696_RS01580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M0696_RS01585	COG1714	RDD family
M0696_RS01590	COG3012	SEC-C Motif Domain Protein
M0696_RS01590	COG1405	negative regulation of cell septum assembly
M0696_RS01600	COG0667	Aldo Keto reductase
M0696_RS01615	COG1595	DNA-templated transcription, initiation
M0696_RS01620	COG1595	DNA-templated transcription, initiation
M0696_RS01625	COG1876	peptidase activity
M0696_RS01630	COG0457	Tetratricopeptide repeat
M0696_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS01640	COG0366	Alpha amylase catalytic
M0696_RS01645	COG0803	Belongs to the bacterial solute-binding protein 9 family
M0696_RS01650	COG1121	(ABC) transporter
M0696_RS01655	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_RS01660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_RS01665	COG2310	stress, protein
M0696_RS01670	COG2310	stress, protein
M0696_RS01675	COG2310	stress, protein
M0696_RS01680	COG0861	Integral membrane protein TerC family
M0696_RS01695	COG1358	cellular component organization or biogenesis
M0696_RS01710	COG3853	Toxic anion resistance protein (TelA)
M0696_RS01715	COG0477	Major facilitator Superfamily
M0696_RS01720	COG2814	Major facilitator Superfamily
M0696_RS01725	COG0640	Transcriptional regulator
M0696_RS01730	COG0517	IMP dehydrogenase activity
M0696_RS01730	COG4175	Glycine betaine
M0696_RS01735	COG4176	ABC-type proline glycine betaine transport system permease component
M0696_RS01740	COG2113	Glycine betaine
M0696_RS01745	COG2323	membrane
M0696_RS01750	COG0038	chloride channel
M0696_RS01765	COG0366	Alpha amylase catalytic
M0696_RS01770	COG0039	L-malate dehydrogenase activity
M0696_RS01775	COG1620	l-lactate permease
M0696_RS01780	COG2814	Major facilitator Superfamily
M0696_RS01785	COG1846	Transcriptional regulator
M0696_RS01790	COG1280	lysine exporter protein (LysE YggA)
M0696_RS01795	COG3403	YqcI/YcgG family
M0696_RS01800	COG1113	amino acid transport
M0696_RS01805	COG3665	Urea carboxylase-associated protein
M0696_RS01810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M0696_RS01815	COG1660	Displays ATPase and GTPase activities
M0696_RS01820	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M0696_RS01825	COG2226	methyltransferase
M0696_RS01830	COG0583	DNA-binding transcription factor activity
M0696_RS01835	COG3458	cephalosporin-C deacetylase activity
M0696_RS01840	COG3541	Predicted nucleotidyltransferase
M0696_RS01845	COG0506	proline dehydrogenase activity
M0696_RS01850	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS01855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS01860	COG2508	Transcriptional regulator
M0696_RS01865	COG3689	TIGRFAM TIGR03943 family protein
M0696_RS01870	COG0701	Predicted permease
M0696_RS01875	COG2267	carboxylic ester hydrolase activity
M0696_RS01880	COG0492	ferredoxin-NADP+ reductase activity
M0696_RS01885	COG1587	Uroporphyrinogen-III synthase
M0696_RS01885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M0696_RS01890	COG2146	nitrite reductase [NAD(P)H] activity
M0696_RS01895	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_RS01900	COG0243	molybdopterin cofactor binding
M0696_RS01905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_RS01910	COG2223	nitrite transmembrane transporter activity
M0696_RS01915	COG1469	GTP cyclohydrolase I activity
M0696_RS01920	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_RS01930	COG0523	cobalamin synthesis protein
M0696_RS01935	COG0765	amino acid transport
M0696_RS01940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_RS01950	COG1714	RDD family
M0696_RS01970	COG3842	ATPase activity
M0696_RS01975	COG2723	6-phospho-beta-galactosidase activity
M0696_RS01985	COG3209	COG3209 Rhs family protein
M0696_RS01990	COG0840	transmembrane signaling receptor activity
M0696_RS01990	COG3290	protein histidine kinase activity
M0696_RS01995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M0696_RS02000	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
M0696_RS02005	COG1733	regulation of RNA biosynthetic process
M0696_RS02010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS02035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS02040	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M0696_RS02055	COG0697	spore germination
M0696_RS02060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS02075	COG0701	Predicted permease
M0696_RS02080	COG2364	Membrane
M0696_RS02085	COG1126	abc transporter atp-binding protein
M0696_RS02090	COG0765	amino acid transport
M0696_RS02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_RS02100	COG0583	DNA-binding transcription factor activity
M0696_RS02105	COG0163	prenyltransferase activity
M0696_RS02110	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
M0696_RS02125	COG0596	Alpha beta hydrolase
M0696_RS02130	COG3104	oligopeptide transport
M0696_RS02135	COG5434	Belongs to the glycosyl hydrolase 28 family
M0696_RS02145	COG0697	spore germination
M0696_RS02155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M0696_RS02160	COG1136	(ABC) transporter
M0696_RS02165	COG0577	efflux transmembrane transporter activity
M0696_RS02170	COG0745	RESPONSE REGULATOR receiver
M0696_RS02175	COG5002	protein histidine kinase activity
M0696_RS02175	COG3850	Histidine kinase
M0696_RS02180	COG0457	Tetratricopeptide repeat
M0696_RS02195	COG0527	aspartate kinase activity
M0696_RS02200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS02205	COG4605	iron ion homeostasis
M0696_RS02210	COG4604	ABC transporter, ATP-binding protein
M0696_RS02215	COG4607	ABC-type enterochelin transport system periplasmic component
M0696_RS02220	COG2814	Major facilitator Superfamily
M0696_RS02225	COG1309	transcriptional regulator
M0696_RS02230	COG0778	Nitroreductase
M0696_RS02235	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M0696_RS02240	COG0640	Transcriptional regulator
M0696_RS02245	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS02250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M0696_RS02255	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS02260	COG4975	Glucose uptake
M0696_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS02270	COG4549	nuclear export factor GLE1
M0696_RS02275	COG1276	copper resistance
M0696_RS02275	COG2372	response to copper ion
M0696_RS02280	COG1349	DNA-binding transcription factor activity
M0696_RS02290	COG2213	PTS system mannitol-specific
M0696_RS02295	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS02300	COG0246	Mannitol dehydrogenase
M0696_RS02305	COG0473	3-isopropylmalate dehydrogenase activity
M0696_RS02310	COG0412	Dienelactone hydrolase
M0696_RS02315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_RS02325	COG0561	phosphatase activity
M0696_RS02330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
M0696_RS02335	COG1914	H( )-stimulated, divalent metal cation uptake system
M0696_RS02340	COG4336	lyase activity
M0696_RS02345	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M0696_RS02350	COG1984	allophanate hydrolase subunit 2
M0696_RS02355	COG1414	Transcriptional regulator
M0696_RS02360	COG2755	lipolytic protein G-D-S-L family
M0696_RS02370	COG2329	Antibiotic biosynthesis monooxygenase
M0696_RS02375	COG0768	penicillin binding
M0696_RS02380	COG4989	oxidoreductase activity
M0696_RS02385	COG3711	transcriptional antiterminator
M0696_RS02390	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS02395	COG2226	methyltransferase
M0696_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS02405	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS02415	COG3871	stress protein (general stress protein 26)
M0696_RS02425	COG2814	Major facilitator Superfamily
M0696_RS02430	COG1522	sequence-specific DNA binding
M0696_RS02435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M0696_RS02435	COG0551	DNA topoisomerase type I activity
M0696_RS02440	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
M0696_RS02445	COG3706	GGDEF domain
M0696_RS02450	COG5298	Protein conserved in bacteria
M0696_RS02455	COG1215	transferase activity, transferring glycosyl groups
M0696_RS02465	COG0531	amino acid
M0696_RS02470	COG0494	nUDIX hydrolase
M0696_RS02475	COG0028	Belongs to the TPP enzyme family
M0696_RS02485	COG1914	H( )-stimulated, divalent metal cation uptake system
M0696_RS02490	COG2261	transglycosylase associated protein
M0696_RS02495	COG4876	unkown
M0696_RS02500	COG2217	Heavy metal translocating P-type atpase
M0696_RS02505	COG3729	General stress protein
M0696_RS02510	COG0662	Cupin 2, conserved barrel domain protein
M0696_RS02515	COG2329	Antibiotic biosynthesis monooxygenase
M0696_RS02520	COG3546	catalase activity
M0696_RS02525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M0696_RS02530	COG3290	protein histidine kinase activity
M0696_RS02535	COG4565	transcriptional regulatory protein
M0696_RS02540	COG1301	dicarboxylic acid transport
M0696_RS02545	COG0628	permease
M0696_RS02550	COG1301	dicarboxylic acid transport
M0696_RS02555	COG1131	(ABC) transporter
M0696_RS02560	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_RS02570	COG1960	acyl-CoA dehydrogenase activity
M0696_RS02585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_RS02590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS02595	COG1181	Belongs to the D-alanine--D-alanine ligase family
M0696_RS02600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M0696_RS02605	COG0513	Belongs to the DEAD box helicase family
M0696_RS02610	COG3402	PFAM membrane-flanked domain
M0696_RS02615	COG3428	Bacterial PH domain
M0696_RS02620	COG0705	Rhomboid family
M0696_RS02625	COG0736	holo-[acyl-carrier-protein] synthase activity
M0696_RS02630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M0696_RS02635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M0696_RS02640	COG0864	Transcriptional regulator
M0696_RS02645	COG2337	Toxic component of a toxin-antitoxin (TA) module
M0696_RS02650	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS02655	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS02660	COG2172	sigma factor antagonist activity
M0696_RS02665	COG2208	phosphoserine phosphatase activity
M0696_RS02670	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS02675	COG2172	sigma factor antagonist activity
M0696_RS02680	COG1191	sigma factor activity
M0696_RS02685	COG2208	phosphoserine phosphatase activity
M0696_RS02690	COG2183	response to ionizing radiation
M0696_RS02700	COG3091	SprT-like family
M0696_RS02770	COG5444	nuclease activity
M0696_RS02785	COG2364	Membrane
M0696_RS02790	COG1846	Transcriptional regulator
M0696_RS02795	COG0456	acetyltransferase
M0696_RS02800	COG2808	Putative FMN-binding domain
M0696_RS02805	COG3239	Fatty acid desaturase
M0696_RS02810	COG1278	Cold shock
M0696_RS02815	COG1278	Cold shock
M0696_RS02825	COG1329	Transcriptional regulator
M0696_RS02830	COG2207	Transcriptional regulator
M0696_RS02830	COG3708	Transcriptional regulator
M0696_RS02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS02840	COG0477	Major facilitator Superfamily
M0696_RS02845	COG1132	(ABC) transporter
M0696_RS02855	COG0640	Transcriptional regulator
M0696_RS02860	COG0346	lactoylglutathione lyase activity
M0696_RS02870	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
M0696_RS02885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M0696_RS02890	COG1522	sequence-specific DNA binding
M0696_RS02895	COG0697	spore germination
M0696_RS02900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS02905	COG2030	dehydratase
M0696_RS02910	COG3545	Serine hydrolase
M0696_RS02915	COG1733	regulation of RNA biosynthetic process
M0696_RS02920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS02930	COG0640	Transcriptional regulator
M0696_RS02935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
M0696_RS02940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_RS02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS02955	COG0697	spore germination
M0696_RS02960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS02965	COG0076	glutamate decarboxylase activity
M0696_RS02970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M0696_RS02975	COG0640	Transcriptional regulator
M0696_RS02980	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M0696_RS02995	COG4585	Histidine kinase
M0696_RS03000	COG2197	response regulator
M0696_RS03005	COG2409	Drug exporters of the RND superfamily
M0696_RS03015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS03020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M0696_RS03025	COG1687	branched-chain amino acid
M0696_RS03030	COG1114	Component of the transport system for branched-chain amino acids
M0696_RS03040	COG1811	Na channel or pump
M0696_RS03045	COG0789	Transcriptional regulator
M0696_RS03045	COG4978	Transcriptional regulator
M0696_RS03050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_RS03055	COG0778	Nitroreductase
M0696_RS03060	COG0346	lactoylglutathione lyase activity
M0696_RS03065	COG2259	Doxx family
M0696_RS03070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS03090	COG2323	membrane
M0696_RS03095	COG2323	membrane
M0696_RS03100	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_RS03115	COG1309	transcriptional regulator
M0696_RS03125	COG0456	acetyltransferase
M0696_RS03135	COG2814	Major facilitator Superfamily
M0696_RS03145	COG0488	(ABC) transporter
M0696_RS03150	COG1113	amino acid transport
M0696_RS03155	COG2318	DinB family
M0696_RS03160	COG1846	Transcriptional regulator
M0696_RS03165	COG2409	Drug exporters of the RND superfamily
M0696_RS03165	COG1033	growth of symbiont in host cell
M0696_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS03180	COG0778	Nitroreductase
M0696_RS03185	COG1846	Transcriptional regulator
M0696_RS03190	COG2814	Major facilitator Superfamily
M0696_RS03195	COG0730	response to heat
M0696_RS03200	COG1802	Transcriptional regulator
M0696_RS03205	COG1388	LysM domain
M0696_RS03205	COG3858	chitin binding
M0696_RS03220	COG1785	Belongs to the alkaline phosphatase family
M0696_RS03230	COG0454	-acetyltransferase
M0696_RS03235	COG1078	dGTPase activity
M0696_RS03240	COG1388	LysM domain
M0696_RS03245	COG2814	Major facilitator Superfamily
M0696_RS03250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_RS03255	COG1447	Phosphotransferase system cellobiose-specific component IIA
M0696_RS03260	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_RS03265	COG2723	6-phospho-beta-galactosidase activity
M0696_RS03270	COG2188	Transcriptional regulator
M0696_RS03275	COG1940	carbohydrate kinase activity
M0696_RS03280	COG1482	cell wall glycoprotein biosynthetic process
M0696_RS03285	COG4124	Belongs to the glycosyl hydrolase 26 family
M0696_RS03330	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M0696_RS03335	COG0802	atpase or kinase
M0696_RS03340	COG1214	PFAM Peptidase M22, glycoprotease
M0696_RS03345	COG0456	acetyltransferase
M0696_RS03350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M0696_RS03355	COG0488	(ABC) transporter
M0696_RS03360	COG0315	cyclic pyranopterin monophosphate synthase activity
M0696_RS03365	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
M0696_RS03370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M0696_RS03375	COG0805	protein transport
M0696_RS03385	COG1266	CAAX protease self-immunity
M0696_RS03395	COG0459	protein refolding
M0696_RS03430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M0696_RS03450	COG1073	alpha beta
M0696_RS03455	COG0457	Tetratricopeptide repeat
M0696_RS03460	COG1063	alcohol dehydrogenase
M0696_RS03465	COG2211	Major facilitator Superfamily
M0696_RS03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_RS03475	COG1842	Phage shock protein A
M0696_RS03480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M0696_RS03485	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M0696_RS03490	COG4260	virion core protein, lumpy skin disease virus
M0696_RS03500	COG2814	Major facilitator Superfamily
M0696_RS03505	COG1063	alcohol dehydrogenase
M0696_RS03510	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M0696_RS03515	COG0823	Involved in the tonB-independent uptake of proteins
M0696_RS03530	COG2267	carboxylic ester hydrolase activity
M0696_RS03540	COG2132	Multicopper oxidase
M0696_RS03545	COG1113	amino acid transport
M0696_RS03550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M0696_RS03555	COG0714	Associated with various cellular activities
M0696_RS03560	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
M0696_RS03565	COG1305	Transglutaminase-like
M0696_RS03570	COG0519	Catalyzes the synthesis of GMP from XMP
M0696_RS03570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M0696_RS03575	COG2252	PERMEase
M0696_RS03580	COG3064	Membrane
M0696_RS03590	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
M0696_RS03600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M0696_RS03605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M0696_RS03610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M0696_RS03615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M0696_RS03620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M0696_RS03625	COG0047	phosphoribosylformylglycinamidine synthase activity
M0696_RS03630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M0696_RS03635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
M0696_RS03640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
M0696_RS03645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M0696_RS03650	COG0138	bifunctional purine biosynthesis protein purh
M0696_RS03655	COG0151	Belongs to the GarS family
M0696_RS03660	COG1522	sequence-specific DNA binding
M0696_RS03665	COG0531	amino acid
M0696_RS03675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M0696_RS03680	COG1470	cell adhesion involved in biofilm formation
M0696_RS03685	COG4496	protein, YerC YecD
M0696_RS03690	COG0069	glutamate synthase activity
M0696_RS03695	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
M0696_RS03700	COG0210	DNA helicase
M0696_RS03705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M0696_RS03710	COG4851	CamS sex pheromone cAM373 precursor
M0696_RS03715	COG2814	Major facilitator Superfamily
M0696_RS03725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_RS03735	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M0696_RS03740	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_RS03785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_RS03790	COG1785	Belongs to the alkaline phosphatase family
M0696_RS03795	COG1285	pathogenesis
M0696_RS03800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS03805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M0696_RS03810	COG0154	amidase activity
M0696_RS03815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M0696_RS03825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M0696_RS03830	COG1597	lipid kinase activity
M0696_RS03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M0696_RS03840	COG2197	response regulator
M0696_RS03850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS03855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_RS03860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS03875	COG1131	(ABC) transporter
M0696_RS03915	COG5444	nuclease activity
M0696_RS03930	COG2323	membrane
M0696_RS03940	COG0457	Tetratricopeptide repeat
M0696_RS03950	COG0217	transcriptional regulatory protein
M0696_RS03960	COG1309	transcriptional regulator
M0696_RS03965	COG3631	Ketosteroid isomerase-related protein
M0696_RS03990	COG3546	catalase activity
M0696_RS03995	COG0454	-acetyltransferase
M0696_RS04005	COG5578	integral membrane protein
M0696_RS04010	COG2972	Histidine kinase
M0696_RS04015	COG4753	response regulator
M0696_RS04015	COG2207	Transcriptional regulator
M0696_RS04020	COG1653	transport
M0696_RS04025	COG1175	transmembrane transport
M0696_RS04030	COG0395	ABC-type sugar transport system, permease component
M0696_RS04035	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
M0696_RS04040	COG2207	Transcriptional regulator
M0696_RS04045	COG2755	lipolytic protein G-D-S-L family
M0696_RS04055	COG5578	integral membrane protein
M0696_RS04060	COG3401	FG-GAP repeat protein
M0696_RS04065	COG3401	FG-GAP repeat protein
M0696_RS04070	COG2755	lipolytic protein G-D-S-L family
M0696_RS04075	COG1874	Beta-galactosidase
M0696_RS04085	COG1653	transport
M0696_RS04090	COG4209	transmembrane transport
M0696_RS04095	COG0395	ABC-type sugar transport system, permease component
M0696_RS04100	COG1486	melibiose metabolic process
M0696_RS04105	COG2323	membrane
M0696_RS04110	COG2329	Antibiotic biosynthesis monooxygenase
M0696_RS04115	COG0346	lactoylglutathione lyase activity
M0696_RS04130	COG5583	Uncharacterized small protein (DUF2292)
M0696_RS04135	COG0670	Belongs to the BI1 family
M0696_RS04145	COG1846	Transcriptional regulator
M0696_RS04150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M0696_RS04170	COG1368	sulfuric ester hydrolase activity
M0696_RS04175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M0696_RS04180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_RS04185	COG1442	glycosyl transferase family 8
M0696_RS04190	COG1216	Glycosyl transferase, family 2
M0696_RS04195	COG1442	glycosyl transferase family 8
M0696_RS04200	COG2223	nitrite transmembrane transporter activity
M0696_RS04205	COG1011	Hydrolase
M0696_RS04210	COG0531	amino acid
M0696_RS04215	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS04220	COG0840	transmembrane signaling receptor activity
M0696_RS04225	COG0488	(ABC) transporter
M0696_RS04235	COG0789	Transcriptional regulator
M0696_RS04240	COG2814	Major facilitator Superfamily
M0696_RS04245	COG0488	(ABC) transporter
M0696_RS04250	COG0513	Belongs to the DEAD box helicase family
M0696_RS04255	COG0456	acetyltransferase
M0696_RS04260	COG2130	NADP-dependent
M0696_RS04265	COG1120	ATPase activity
M0696_RS04270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS04275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS04280	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M0696_RS04295	COG3866	Pectate lyase
M0696_RS04300	COG0471	metal ion transport
M0696_RS04305	COG3290	protein histidine kinase activity
M0696_RS04310	COG4565	transcriptional regulatory protein
M0696_RS04315	COG3181	Tripartite tricarboxylate transporter family receptor
M0696_RS04320	COG2851	Citrate transporter
M0696_RS04325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS04330	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
M0696_RS04335	COG1254	Belongs to the acylphosphatase family
M0696_RS04340	COG2258	MOSC domain
M0696_RS04360	COG0024	Methionine aminopeptidase
M0696_RS04365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS04365	COG1263	PTS System
M0696_RS04370	COG1368	sulfuric ester hydrolase activity
M0696_RS04385	COG1115	amino acid carrier protein
M0696_RS04390	COG0531	amino acid
M0696_RS04405	COG0697	spore germination
M0696_RS04410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS04410	COG1263	PTS System
M0696_RS04415	COG0366	Alpha amylase catalytic
M0696_RS04420	COG2188	Transcriptional regulator
M0696_RS04425	COG0778	Nitroreductase
M0696_RS04430	COG0737	Belongs to the 5'-nucleotidase family
M0696_RS04435	COG0693	protein deglycase activity
M0696_RS04440	COG2814	Major facilitator Superfamily
M0696_RS04445	COG4840	Belongs to the UPF0435 family
M0696_RS04450	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_RS04455	COG4980	gas vesicle protein
M0696_RS04460	COG1295	ribonuclease BN
M0696_RS04465	COG0477	Major facilitator Superfamily
M0696_RS04470	COG0387	Pfam Sodium calcium exchanger
M0696_RS04480	COG0668	transmembrane transport
M0696_RS04485	COG0535	radical SAM domain protein
M0696_RS04495	COG0726	polysaccharide deacetylase
M0696_RS04500	COG2084	Dehydrogenase
M0696_RS04505	COG0598	Magnesium transport protein CorA
M0696_RS04510	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M0696_RS04520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M0696_RS04535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M0696_RS04545	COG4637	Psort location Cytoplasmic, score
M0696_RS04555	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_RS04560	COG0022	dehydrogenase e1 component
M0696_RS04565	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_RS04570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_RS04575	COG3284	Transcriptional regulator
M0696_RS04585	COG1742	UPF0060 membrane protein
M0696_RS04605	COG4842	Belongs to the WXG100 family
M0696_RS04610	COG1486	melibiose metabolic process
M0696_RS04615	COG1737	Transcriptional regulator
M0696_RS04620	COG1263	PTS System
M0696_RS04620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS04625	COG1132	(ABC) transporter
M0696_RS04630	COG1132	(ABC) transporter
M0696_RS04635	COG2259	Doxx family
M0696_RS04640	COG2514	catechol 2,3-dioxygenase activity
M0696_RS04645	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS04645	COG4977	sequence-specific DNA binding
M0696_RS04650	COG2814	Major facilitator Superfamily
M0696_RS04655	COG1082	Xylose isomerase domain protein TIM barrel
M0696_RS04660	COG0673	inositol 2-dehydrogenase activity
M0696_RS04670	COG2197	response regulator
M0696_RS04675	COG1131	(ABC) transporter
M0696_RS04680	COG0842	Transport permease protein
M0696_RS04680	COG1511	domain protein
M0696_RS04685	COG0842	Transport permease protein
M0696_RS04695	COG1695	Transcriptional regulator
M0696_RS04700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M0696_RS04705	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
M0696_RS04710	COG2318	DinB family
M0696_RS04715	COG2814	Major facilitator Superfamily
M0696_RS04720	COG1846	Transcriptional regulator
M0696_RS04725	COG0392	lysyltransferase activity
M0696_RS04725	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
M0696_RS04730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS04735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS04740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS04745	COG0384	phenazine biosynthesis protein PhzF
M0696_RS04750	COG0778	Nitroreductase
M0696_RS04765	COG1090	epimerase
M0696_RS04770	COG2137	regulation of response to DNA damage stimulus
M0696_RS04780	COG2814	Major facilitator Superfamily
M0696_RS04795	COG3103	Sh3 type 3 domain protein
M0696_RS04800	COG5658	integral membrane protein
M0696_RS04805	COG0596	Alpha beta hydrolase
M0696_RS04810	COG0463	Glycosyl transferase, family 2
M0696_RS04815	COG4485	Bacterial membrane protein, YfhO
M0696_RS04820	COG1988	membrane-bound metal-dependent
M0696_RS04825	COG1194	a g-specific adenine glycosylase
M0696_RS04835	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS04850	COG3557	Belongs to the UPF0374 family
M0696_RS04855	COG1132	(ABC) transporter
M0696_RS04860	COG4129	membrane
M0696_RS04865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M0696_RS04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M0696_RS04875	COG0735	belongs to the Fur family
M0696_RS04985	COG4326	sporulation control protein
M0696_RS04995	COG5577	PFAM Coat F domain
M0696_RS05000	COG3340	Belongs to the peptidase S51 family
M0696_RS05005	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M0696_RS05015	COG0753	catalase activity
M0696_RS05020	COG1116	anion transmembrane transporter activity
M0696_RS05025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M0696_RS05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M0696_RS05035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_RS05045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M0696_RS05055	COG1476	TRANSCRIPTIONal
M0696_RS05065	COG3382	B3 4 domain protein
M0696_RS05070	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M0696_RS05080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M0696_RS05085	COG0789	Transcriptional regulator
M0696_RS05090	COG1664	Polymer-forming cytoskeletal
M0696_RS05095	COG1664	Polymer-forming cytoskeletal
M0696_RS05100	COG2766	serine protein kinase
M0696_RS05105	COG2718	Belongs to the UPF0229 family
M0696_RS05110	COG1846	Transcriptional regulator
M0696_RS05115	COG1566	PFAM secretion protein HlyD family protein
M0696_RS05120	COG2814	Major facilitator Superfamily
M0696_RS05125	COG0655	NAD(P)H dehydrogenase (quinone) activity
M0696_RS05140	COG1725	Transcriptional regulator
M0696_RS05145	COG1131	(ABC) transporter
M0696_RS05150	COG1131	(ABC) transporter
M0696_RS05155	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_RS05160	COG1278	Cold shock
M0696_RS05165	COG1464	Belongs to the NlpA lipoprotein family
M0696_RS05170	COG3706	GGDEF domain
M0696_RS05175	COG1823	symporter activity
M0696_RS05195	COG5577	PFAM Coat F domain
M0696_RS05200	COG4085	toxin activity
M0696_RS05200	COG1525	nuclease
M0696_RS05200	COG0737	Belongs to the 5'-nucleotidase family
M0696_RS05205	COG3764	Sortase (surface protein transpeptidase)
M0696_RS05210	COG0564	pseudouridine synthase activity
M0696_RS05220	COG0517	IMP dehydrogenase activity
M0696_RS05225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M0696_RS05230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M0696_RS05230	COG3153	acetyltransferase
M0696_RS05240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_RS05245	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
M0696_RS05250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M0696_RS05255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M0696_RS05260	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M0696_RS05265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M0696_RS05270	COG4585	Histidine kinase
M0696_RS05270	COG2203	Gaf domain
M0696_RS05275	COG2197	response regulator
M0696_RS05280	COG0431	NADPH-dependent FMN reductase
M0696_RS05295	COG0791	NLP P60 protein
M0696_RS05295	COG1388	LysM domain
M0696_RS05300	COG1959	2 iron, 2 sulfur cluster binding
M0696_RS05310	COG2719	SpoVR family
M0696_RS05315	COG1785	Belongs to the alkaline phosphatase family
M0696_RS05320	COG1388	LysM domain
M0696_RS05320	COG0791	NLP P60 protein
M0696_RS05325	COG0583	DNA-binding transcription factor activity
M0696_RS05330	COG0372	Belongs to the citrate synthase family
M0696_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS05340	COG0531	amino acid
M0696_RS05345	COG0733	neurotransmitter:sodium symporter activity
M0696_RS05350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS05355	COG0456	acetyltransferase
M0696_RS05370	COG1595	DNA-templated transcription, initiation
M0696_RS05375	COG0667	Aldo Keto reductase
M0696_RS05380	COG0204	Acyl-transferase
M0696_RS05385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_RS05395	COG1253	flavin adenine dinucleotide binding
M0696_RS05400	COG0789	Transcriptional regulator
M0696_RS05405	COG0436	Aminotransferase
M0696_RS05410	COG1253	flavin adenine dinucleotide binding
M0696_RS05415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M0696_RS05420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M0696_RS05425	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_RS05435	COG0668	transmembrane transport
M0696_RS05440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M0696_RS05445	COG0726	polysaccharide deacetylase
M0696_RS05450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_RS05455	COG1757	Na H antiporter
M0696_RS05460	COG0589	response to stress
M0696_RS05470	COG1132	(ABC) transporter
M0696_RS05475	COG1132	(ABC) transporter
M0696_RS05480	COG0702	epimerase
M0696_RS05500	COG0189	ligase activity
M0696_RS05505	COG0189	ligase activity
M0696_RS05510	COG4399	Belongs to the UPF0754 family
M0696_RS05515	COG3679	Belongs to the UPF0342 family
M0696_RS05520	COG4335	DNA alkylation repair
M0696_RS05525	COG0561	phosphatase activity
M0696_RS05530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M0696_RS05535	COG0475	glutathione-regulated potassium exporter activity
M0696_RS05540	COG0490	domain, Protein
M0696_RS05550	COG1024	Enoyl-CoA hydratase
M0696_RS05560	COG4152	abc transporter atp-binding protein
M0696_RS05565	COG1668	transmembrane transport
M0696_RS05570	COG0420	3'-5' exonuclease activity
M0696_RS05575	COG4717	serine-type aminopeptidase activity
M0696_RS05580	COG3481	metal-dependent phosphohydrolase, HD sub domain
M0696_RS05590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M0696_RS05620	COG1846	Transcriptional regulator
M0696_RS05625	COG4980	gas vesicle protein
M0696_RS05640	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M0696_RS05645	COG0537	adenosine 5'-monophosphoramidase activity
M0696_RS05650	COG1131	(ABC) transporter
M0696_RS05655	COG4473	ABC transporter
M0696_RS05665	COG1473	amidohydrolase
M0696_RS05670	COG3069	C4-dicarboxylate transmembrane transporter activity
M0696_RS05680	COG2329	Antibiotic biosynthesis monooxygenase
M0696_RS05685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_RS05690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M0696_RS05695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M0696_RS05700	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
M0696_RS05705	COG1309	transcriptional regulator
M0696_RS05710	COG1511	domain protein
M0696_RS05715	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_RS05720	COG4377	Putative membrane peptidase family (DUF2324)
M0696_RS05725	COG1363	Peptidase, m42
M0696_RS05730	COG4405	Protein conserved in bacteria
M0696_RS05735	COG1301	dicarboxylic acid transport
M0696_RS05745	COG1234	tRNA 3'-trailer cleavage
M0696_RS05750	COG0095	Lipoate-protein ligase
M0696_RS05755	COG0702	epimerase
M0696_RS05760	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS05770	COG0501	Belongs to the peptidase M48B family
M0696_RS05785	COG0604	alcohol dehydrogenase
M0696_RS05790	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
M0696_RS05795	COG0406	alpha-ribazole phosphatase activity
M0696_RS05800	COG0183	Belongs to the thiolase family
M0696_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS05810	COG1268	BioY protein
M0696_RS05815	COG0840	transmembrane signaling receptor activity
M0696_RS05820	COG0723	plastoquinol--plastocyanin reductase activity
M0696_RS05820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_RS05825	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS05835	COG4903	ComK protein
M0696_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS05850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS05865	COG0398	Pfam SNARE associated Golgi protein
M0696_RS05870	COG0681	Belongs to the peptidase S26 family
M0696_RS05875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M0696_RS05880	COG1846	Transcriptional regulator
M0696_RS05885	COG3180	Ammonia monooxygenase
M0696_RS05890	COG2814	Major facilitator Superfamily
M0696_RS05890	COG0477	Major facilitator Superfamily
M0696_RS05895	COG4533	DNA binding
M0696_RS05905	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M0696_RS05910	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
M0696_RS05915	COG1074	ATP-dependent DNA helicase activity
M0696_RS05920	COG0420	3'-5' exonuclease activity
M0696_RS05925	COG0419	ATPase involved in DNA repair
M0696_RS05930	COG1403	HNH endonuclease
M0696_RS05970	COG5337	Spore coat protein CotH
M0696_RS05975	COG0179	Fumarylacetoacetate (FAA) hydrolase
M0696_RS05985	COG1404	Belongs to the peptidase S8 family
M0696_RS05995	COG0367	asparagine synthase
M0696_RS06005	COG0534	Mate efflux family protein
M0696_RS06010	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS06010	COG2207	Transcriptional regulator
M0696_RS06015	COG1609	Transcriptional regulator
M0696_RS06020	COG0673	inositol 2-dehydrogenase activity
M0696_RS06025	COG2318	DinB family
M0696_RS06035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M0696_RS06040	COG1357	PFAM Pentapeptide repeats (8 copies)
M0696_RS06045	COG2267	carboxylic ester hydrolase activity
M0696_RS06050	COG0529	Catalyzes the synthesis of activated sulfate
M0696_RS06055	COG2046	Belongs to the sulfate adenylyltransferase family
M0696_RS06060	COG0175	sulfate reduction
M0696_RS06065	COG2045	Belongs to the ComB family
M0696_RS06070	COG1809	phosphosulfolactate synthase activity
M0696_RS06075	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS06080	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_RS06085	COG2814	Major facilitator Superfamily
M0696_RS06090	COG0454	-acetyltransferase
M0696_RS06095	COG2153	protein acetylation
M0696_RS06100	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M0696_RS06100	COG0646	methionine synthase
M0696_RS06105	COG1666	GTP binding
M0696_RS06120	COG1307	EDD domain protein, DegV family
M0696_RS06125	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS06145	COG0561	phosphatase activity
M0696_RS06150	COG1073	alpha beta
M0696_RS06155	COG2151	metal-sulfur cluster biosynthetic enzyme
M0696_RS06165	COG0277	FAD linked oxidase domain protein
M0696_RS06170	COG2271	Major facilitator Superfamily
M0696_RS06175	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M0696_RS06180	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M0696_RS06190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M0696_RS06195	COG0505	Belongs to the CarA family
M0696_RS06200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M0696_RS06205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M0696_RS06220	COG2267	carboxylic ester hydrolase activity
M0696_RS06230	COG1744	ABC transporter substrate-binding protein PnrA-like
M0696_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_RS06250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_RS06255	COG5504	Zn-dependent protease
M0696_RS06260	COG0444	Belongs to the ABC transporter superfamily
M0696_RS06265	COG4608	Belongs to the ABC transporter superfamily
M0696_RS06275	COG0601	transmembrane transport
M0696_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_RS06290	COG0180	Tryptophanyl-tRNA synthetase
M0696_RS06295	COG4166	transmembrane transport
M0696_RS06300	COG0601	transmembrane transport
M0696_RS06305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_RS06310	COG0444	Belongs to the ABC transporter superfamily
M0696_RS06315	COG4608	Belongs to the ABC transporter superfamily
M0696_RS06320	COG2814	Major facilitator Superfamily
M0696_RS06325	COG0456	acetyltransferase
M0696_RS06330	COG1393	Belongs to the ArsC family
M0696_RS06335	COG0861	Integral membrane protein TerC family
M0696_RS06345	COG4862	establishment of competence for transformation
M0696_RS06355	COG4469	Competence protein
M0696_RS06360	COG1164	Oligoendopeptidase f
M0696_RS06370	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M0696_RS06375	COG2346	COG2346, Truncated hemoglobins
M0696_RS06380	COG0741	lytic transglycosylase activity
M0696_RS06385	COG4116	CYTH
M0696_RS06395	COG2357	RelA SpoT domain protein
M0696_RS06400	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M0696_RS06405	COG0564	pseudouridine synthase activity
M0696_RS06410	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M0696_RS06415	COG0569	domain protein
M0696_RS06415	COG0475	glutathione-regulated potassium exporter activity
M0696_RS06420	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M0696_RS06425	COG0352	thiamine-phosphate diphosphorylase activity
M0696_RS06430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_RS06435	COG2104	thiamine diphosphate biosynthetic process
M0696_RS06440	COG2022	thiamine diphosphate biosynthetic process
M0696_RS06445	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M0696_RS06450	COG0351	phosphomethylpyrimidine kinase
M0696_RS06455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
M0696_RS06510	COG0210	DNA helicase
M0696_RS06520	COG2153	protein acetylation
M0696_RS06525	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M0696_RS06530	COG2382	esterase
M0696_RS06535	COG0626	cystathionine gamma-synthase activity
M0696_RS06540	COG0626	cystathionine gamma-synthase activity
M0696_RS06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS06550	COG5505	Protein of unknown function (DUF819)
M0696_RS06565	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M0696_RS06570	COG3711	transcriptional antiterminator
M0696_RS06570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS06575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_RS06575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_RS06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS06580	COG1482	cell wall glycoprotein biosynthetic process
M0696_RS06600	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M0696_RS06610	COG0109	protoheme IX farnesyltransferase activity
M0696_RS06620	COG0726	polysaccharide deacetylase
M0696_RS06635	COG5504	Zn-dependent protease
M0696_RS06640	COG2205	protein histidine kinase activity
M0696_RS06650	COG3383	formate dehydrogenase (NAD+) activity
M0696_RS06655	COG2427	Protein of unknown function (DUF1641)
M0696_RS06665	COG1051	belongs to the nudix hydrolase family
M0696_RS06675	COG2124	cytochrome p450
M0696_RS06680	COG1819	glycosyl
M0696_RS06690	COG1587	Uroporphyrinogen-III synthase
M0696_RS06695	COG0390	transport system, permease component
M0696_RS06700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_RS06705	COG0697	spore germination
M0696_RS06710	COG4297	protein containing double-stranded beta helix domain
M0696_RS06720	COG1252	NADH dehydrogenase
M0696_RS06725	COG1904	glucuronate isomerase
M0696_RS06730	COG2211	Major facilitator Superfamily
M0696_RS06735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
M0696_RS06740	COG1063	alcohol dehydrogenase
M0696_RS06745	COG1312	Catalyzes the dehydration of D-mannonate
M0696_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS06755	COG2271	Major facilitator Superfamily
M0696_RS06760	COG1609	Transcriptional regulator
M0696_RS06765	COG0246	Mannitol dehydrogenase
M0696_RS06770	COG2721	sulfolactate sulfo-lyase activity
M0696_RS06775	COG0730	response to heat
M0696_RS06780	COG2318	DinB family
M0696_RS06790	COG0457	Tetratricopeptide repeat
M0696_RS06800	COG2350	Protein conserved in bacteria
M0696_RS06805	COG1388	LysM domain
M0696_RS06805	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS06805	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_RS06815	COG4195	phage-related replication protein
M0696_RS06820	COG3546	catalase activity
M0696_RS06825	COG2856	Zn peptidase
M0696_RS06830	COG1396	sequence-specific DNA binding
M0696_RS06840	COG1522	sequence-specific DNA binding
M0696_RS06845	COG1484	DNA-dependent DNA replication
M0696_RS06865	COG1595	DNA-templated transcription, initiation
M0696_RS06870	COG5484	DNA packaging
M0696_RS06870	COG3728	DNA packaging
M0696_RS06875	COG1783	phage Terminase large subunit
M0696_RS06880	COG5518	Phage portal protein
M0696_RS06885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M0696_RS06890	COG4653	Phage capsid family
M0696_RS06940	COG3953	SLT domain
M0696_RS06940	COG5412	phage tail tape measure protein
M0696_RS06945	COG1652	LysM domain
M0696_RS06950	COG4193	domain, Protein
M0696_RS06960	COG3628	GPW Gp25 family protein
M0696_RS06965	COG3299	homolog of phage Mu protein gp47
M0696_RS06970	COG3778	Protein conserved in bacteria
M0696_RS07010	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS07010	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_RS07030	COG0306	phosphate transporter
M0696_RS07035	COG1392	Phosphate transport regulator
M0696_RS07040	COG0531	amino acid
M0696_RS07045	COG0346	lactoylglutathione lyase activity
M0696_RS07055	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M0696_RS07060	COG0463	Glycosyl transferase, family 2
M0696_RS07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_RS07075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_RS07080	COG2362	D-Aminopeptidase
M0696_RS07085	COG0601	transmembrane transport
M0696_RS07090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M0696_RS07095	COG0444	Belongs to the ABC transporter superfamily
M0696_RS07100	COG4166	transmembrane transport
M0696_RS07105	COG1619	proteins homologs of microcin C7 resistance protein MccF
M0696_RS07110	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_RS07115	COG0791	NLP P60 protein
M0696_RS07120	COG4608	Belongs to the ABC transporter superfamily
M0696_RS07125	COG2706	6-phosphogluconolactonase activity
M0696_RS07135	COG1607	acyl-coa hydrolase
M0696_RS07140	COG1017	nitric oxide dioxygenase activity
M0696_RS07140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M0696_RS07150	COG2323	membrane
M0696_RS07155	COG2318	DinB family
M0696_RS07160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS07165	COG2076	Multidrug Resistance protein
M0696_RS07170	COG2076	Multidrug Resistance protein
M0696_RS07175	COG0788	formyltetrahydrofolate deformylase activity
M0696_RS07180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M0696_RS07185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
M0696_RS07190	COG1764	response to oxidative stress
M0696_RS07195	COG1846	Transcriptional regulator
M0696_RS07200	COG1764	response to oxidative stress
M0696_RS07205	COG0457	Tetratricopeptide repeat
M0696_RS07205	COG0463	Glycosyl transferase, family 2
M0696_RS07210	COG0590	tRNA wobble adenosine to inosine editing
M0696_RS07215	COG0406	alpha-ribazole phosphatase activity
M0696_RS07220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_RS07225	COG1404	Belongs to the peptidase S8 family
M0696_RS07230	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS07235	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M0696_RS07240	COG1122	ATPase activity
M0696_RS07245	COG4721	ABC-type cobalt transport system, permease component
M0696_RS07255	COG0745	RESPONSE REGULATOR receiver
M0696_RS07260	COG3850	Histidine kinase
M0696_RS07260	COG5002	protein histidine kinase activity
M0696_RS07265	COG3212	peptidase
M0696_RS07270	COG3212	peptidase
M0696_RS07280	COG2239	Acts as a magnesium transporter
M0696_RS07285	COG0789	Transcriptional regulator
M0696_RS07300	COG1846	Transcriptional regulator
M0696_RS07305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_RS07310	COG0726	polysaccharide deacetylase
M0696_RS07315	COG1408	metallophosphoesterase
M0696_RS07325	COG0463	Glycosyl transferase, family 2
M0696_RS07330	COG3285	dna ligase
M0696_RS07330	COG1793	dna ligase
M0696_RS07335	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
M0696_RS07340	COG5001	Diguanylate cyclase
M0696_RS07340	COG3300	MHYT domain
M0696_RS07345	COG0586	Pfam SNARE associated Golgi protein
M0696_RS07350	COG0861	Integral membrane protein TerC family
M0696_RS07355	COG1191	sigma factor activity
M0696_RS07375	COG0501	Belongs to the peptidase M48B family
M0696_RS07380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M0696_RS07395	COG3594	Acyltransferase
M0696_RS07400	COG5002	protein histidine kinase activity
M0696_RS07405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M0696_RS07415	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
M0696_RS07420	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
M0696_RS07425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M0696_RS07430	COG0436	Aminotransferase
M0696_RS07435	COG1850	ribulose-bisphosphate carboxylase activity
M0696_RS07440	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
M0696_RS07445	COG0235	Class ii aldolase
M0696_RS07450	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
M0696_RS07455	COG3339	Conserved Protein
M0696_RS07470	COG3852	Histidine kinase
M0696_RS07475	COG1846	Transcriptional regulator
M0696_RS07480	COG1360	Flagellar Motor Protein
M0696_RS07485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M0696_RS07490	COG0542	response to heat
M0696_RS07495	COG3949	Membrane
M0696_RS07500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M0696_RS07505	COG0720	synthase
M0696_RS07510	COG0602	queuosine metabolic process
M0696_RS07515	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
M0696_RS07520	COG1733	regulation of RNA biosynthetic process
M0696_RS07525	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS07540	COG1388	LysM domain
M0696_RS07540	COG4641	Protein conserved in bacteria
M0696_RS07545	COG1388	LysM domain
M0696_RS07550	COG3858	chitin binding
M0696_RS07560	COG4873	Protein conserved in bacteria
M0696_RS07570	COG3773	Cell wall hydrolase
M0696_RS07575	COG2244	polysaccharide biosynthetic process
M0696_RS07580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS07585	COG2217	Heavy metal translocating P-type atpase
M0696_RS07595	COG0006	proline dipeptidase activity
M0696_RS07600	COG1609	Transcriptional regulator
M0696_RS07605	COG3711	transcriptional antiterminator
M0696_RS07610	COG1263	PTS System
M0696_RS07610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS07610	COG2190	(PTS) system
M0696_RS07615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS07620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M0696_RS07630	COG1533	DNA photolyase activity
M0696_RS07635	COG0456	acetyltransferase
M0696_RS07640	COG0840	transmembrane signaling receptor activity
M0696_RS07645	COG2084	Dehydrogenase
M0696_RS07650	COG4257	antibiotic catabolic process
M0696_RS07655	COG2340	Cysteine-rich secretory protein family
M0696_RS07660	COG0768	penicillin binding
M0696_RS07665	COG4191	Histidine kinase
M0696_RS07670	COG0436	Aminotransferase
M0696_RS07680	COG0835	chemotaxis
M0696_RS07680	COG0784	Response regulator, receiver
M0696_RS07690	COG2814	Major facilitator Superfamily
M0696_RS07695	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_RS07700	COG1408	metallophosphoesterase
M0696_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS07710	COG2200	EAL domain
M0696_RS07715	COG4703	Protein of unknown function (DUF1797)
M0696_RS07720	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
M0696_RS07730	COG0517	IMP dehydrogenase activity
M0696_RS07735	COG0583	DNA-binding transcription factor activity
M0696_RS07740	COG0716	FMN binding
M0696_RS07750	COG0716	FMN binding
M0696_RS07755	COG2171	N-acyltransferase activity
M0696_RS07760	COG1473	amidohydrolase
M0696_RS07770	COG0668	transmembrane transport
M0696_RS07775	COG0450	alkyl hydroperoxide reductase
M0696_RS07780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS07795	COG0746	molybdenum cofactor guanylyltransferase activity
M0696_RS07800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M0696_RS07805	COG0303	'Molybdopterin
M0696_RS07810	COG1763	Mo-molybdopterin cofactor biosynthetic process
M0696_RS07815	COG0314	molybdopterin synthase activity
M0696_RS07820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M0696_RS07825	COG1132	(ABC) transporter
M0696_RS07830	COG1132	(ABC) transporter
M0696_RS07840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M0696_RS07845	COG1136	(ABC) transporter
M0696_RS07850	COG0577	efflux transmembrane transporter activity
M0696_RS07855	COG1349	DNA-binding transcription factor activity
M0696_RS07860	COG1105	Belongs to the carbohydrate kinase PfkB family
M0696_RS07865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS07865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_RS07865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M0696_RS07870	COG0681	Belongs to the peptidase S26 family
M0696_RS07880	COG0488	(ABC) transporter
M0696_RS07885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M0696_RS07890	COG2309	aminopeptidase activity
M0696_RS07900	COG1077	Cell shape determining protein MreB Mrl
M0696_RS07905	COG2002	toxin-antitoxin pair type II binding
M0696_RS07910	COG3852	Histidine kinase
M0696_RS07915	COG2105	PFAM AIG2 family protein
M0696_RS07915	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
M0696_RS07920	COG0569	domain protein
M0696_RS07925	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M0696_RS07930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M0696_RS07935	COG5503	Protein of unknown function (DUF1447)
M0696_RS07940	COG0561	phosphatase activity
M0696_RS07945	COG0242	peptide deformylase activity
M0696_RS07955	COG0497	DNA recombination
M0696_RS07960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_RS07965	COG0022	dehydrogenase e1 component
M0696_RS07970	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_RS07975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_RS07980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS07990	COG1982	Orn Lys Arg decarboxylase major
M0696_RS07995	COG4476	Belongs to the UPF0223 family
M0696_RS08000	COG4493	Belongs to the UPF0637 family
M0696_RS08010	COG0483	inositol monophosphate 1-phosphatase activity
M0696_RS08020	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M0696_RS08040	COG1595	DNA-templated transcription, initiation
M0696_RS08060	COG1217	gtp-binding protein TYPA
M0696_RS08070	COG4896	Protein conserved in bacteria
M0696_RS08080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M0696_RS08085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M0696_RS08090	COG2066	Belongs to the glutaminase family
M0696_RS08095	COG4838	Belongs to the UPF0358 family
M0696_RS08100	COG0772	Belongs to the SEDS family
M0696_RS08105	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
M0696_RS08110	COG1612	heme a metabolic process
M0696_RS08115	COG0109	protoheme IX farnesyltransferase activity
M0696_RS08120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M0696_RS08120	COG2010	Cytochrome c
M0696_RS08125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M0696_RS08130	COG1845	cytochrome c oxidase, subunit III
M0696_RS08135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M0696_RS08140	COG3336	cytochrome c oxidase
M0696_RS08150	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
M0696_RS08155	COG2340	Cysteine-rich secretory protein family
M0696_RS08170	COG3679	Belongs to the UPF0342 family
M0696_RS08175	COG4471	UPF0298 protein
M0696_RS08180	COG0742	ribosomal rna small subunit methyltransferase
M0696_RS08185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
M0696_RS08190	COG3314	Sporulation integral membrane protein YlbJ
M0696_RS08195	COG1752	Esterase of the alpha-beta hydrolase superfamily
M0696_RS08200	COG3480	Lon protease (S16) C-terminal proteolytic domain
M0696_RS08205	COG1323	Belongs to the UPF0348 family
M0696_RS08215	COG1399	metal-binding, possibly nucleic acid-binding protein
M0696_RS08230	COG0454	-acetyltransferase
M0696_RS08235	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
M0696_RS08240	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
M0696_RS08245	COG2001	Belongs to the MraZ family
M0696_RS08250	COG0275	rRNA processing
M0696_RS08255	COG4839	cell division protein FtsL
M0696_RS08260	COG0768	penicillin binding
M0696_RS08265	COG0768	penicillin binding
M0696_RS08270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M0696_RS08275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M0696_RS08280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M0696_RS08285	COG0772	Belongs to the SEDS family
M0696_RS08290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_RS08295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M0696_RS08300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M0696_RS08305	COG3879	Bacterial protein of unknown function (DUF881)
M0696_RS08310	COG3879	Bacterial protein of unknown function (DUF881)
M0696_RS08315	COG3856	small basic protein
M0696_RS08320	COG0849	cell division
M0696_RS08325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M0696_RS08330	COG4412	M6 family metalloprotease domain protein
M0696_RS08330	COG1404	Belongs to the peptidase S8 family
M0696_RS08340	COG1191	sigma factor activity
M0696_RS08345	COG1191	sigma factor activity
M0696_RS08350	COG1119	ATPase activity
M0696_RS08355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_RS08360	COG1873	PFAM PRC-barrel domain
M0696_RS08365	COG1496	oxidoreductase activity
M0696_RS08370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M0696_RS08375	COG1799	cell septum assembly
M0696_RS08380	COG0762	integral membrane protein
M0696_RS08385	COG2302	S4 RNA-binding domain
M0696_RS08390	COG3599	regulation of cell shape
M0696_RS08395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M0696_RS08400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_RS08405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
M0696_RS08410	COG0564	pseudouridine synthase activity
M0696_RS08415	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
M0696_RS08420	COG2233	PERMEase
M0696_RS08425	COG0540	Belongs to the ATCase OTCase family
M0696_RS08430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M0696_RS08435	COG0505	Belongs to the CarA family
M0696_RS08440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M0696_RS08445	COG0543	2 iron, 2 sulfur cluster binding
M0696_RS08450	COG0167	dihydroorotate dehydrogenase activity
M0696_RS08455	COG0284	orotidine-5'-phosphate decarboxylase activity
M0696_RS08460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M0696_RS08465	COG0175	sulfate reduction
M0696_RS08470	COG0306	phosphate transporter
M0696_RS08475	COG2046	Belongs to the sulfate adenylyltransferase family
M0696_RS08480	COG0529	Catalyzes the synthesis of activated sulfate
M0696_RS08485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M0696_RS08490	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
M0696_RS08495	COG1648	precorrin-2 dehydrogenase activity
M0696_RS08500	COG1293	RNA-binding protein homologous to eukaryotic snRNP
M0696_RS08505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M0696_RS08510	COG1561	YicC-like family, N-terminal region
M0696_RS08520	COG0194	GDP metabolic process
M0696_RS08525	COG1758	RNA polymerase activity
M0696_RS08530	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M0696_RS08535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M0696_RS08540	COG0242	peptide deformylase activity
M0696_RS08545	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M0696_RS08550	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M0696_RS08550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M0696_RS08555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M0696_RS08560	COG0631	protein serine/threonine phosphatase activity
M0696_RS08565	COG0515	serine threonine protein kinase
M0696_RS08565	COG2815	serine threonine protein kinase
M0696_RS08570	COG1162	GTPase activity
M0696_RS08575	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M0696_RS08580	COG1564	THIamine pyrophosphokinase
M0696_RS08590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M0696_RS08595	COG1302	Protein conserved in bacteria
M0696_RS08600	COG1461	Dihydroxyacetone kinase
M0696_RS08605	COG1760	l-serine dehydratase
M0696_RS08610	COG1760	l-serine dehydratase
M0696_RS08615	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M0696_RS08620	COG1349	DNA-binding transcription factor activity
M0696_RS08620	COG2050	protein possibly involved in aromatic compounds catabolism
M0696_RS08625	COG0416	fatty acid biosynthetic process
M0696_RS08630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS08645	COG0571	ribonuclease III activity
M0696_RS08650	COG1196	nuclear chromosome segregation
M0696_RS08655	COG0552	protein localization to endoplasmic reticulum
M0696_RS08665	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
M0696_RS08670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M0696_RS08675	COG0228	four-way junction DNA binding
M0696_RS08680	COG1837	Belongs to the UPF0109 family
M0696_RS08690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M0696_RS08695	COG0336	Belongs to the RNA methyltransferase TrmD family
M0696_RS08700	COG0335	large ribosomal subunit rRNA binding
M0696_RS08705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M0696_RS08710	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M0696_RS08720	COG2257	FlhB HrpN YscU SpaS Family
M0696_RS08725	COG0045	succinate-CoA ligase (ADP-forming) activity
M0696_RS08730	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M0696_RS08735	COG0758	DNA mediated transformation
M0696_RS08740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M0696_RS08745	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
M0696_RS08750	COG4974	Belongs to the 'phage' integrase family
M0696_RS08755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
M0696_RS08760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
M0696_RS08765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M0696_RS08770	COG1815	bacterial-type flagellum-dependent cell motility
M0696_RS08775	COG1558	bacterial-type flagellum-dependent cell motility
M0696_RS08780	COG1677	Flagellar hook-basal body complex protein FliE
M0696_RS08785	COG1766	The M ring may be actively involved in energy transduction
M0696_RS08790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_RS08795	COG1317	bacterial-type flagellum organization
M0696_RS08800	COG1157	protein secretion by the type III secretion system
M0696_RS08805	COG2882	bacterial-type flagellum organization
M0696_RS08810	COG3334	PFAM MgtE intracellular
M0696_RS08815	COG3144	bacterial-type flagellum assembly
M0696_RS08820	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
M0696_RS08825	COG4786	Flagellar basal body rod
M0696_RS08830	COG1582	Flagellar protein (FlbD)
M0696_RS08835	COG1580	Controls the rotational direction of flagella during chemotaxis
M0696_RS08840	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_RS08845	COG1776	CheC inhibitor of MCP methylation
M0696_RS08845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M0696_RS08850	COG2201	protein-glutamate methylesterase activity
M0696_RS08855	COG3190	flagellar
M0696_RS08860	COG1338	Plays a role in the flagellum-specific transport system
M0696_RS08865	COG1987	bacterial-type flagellum assembly
M0696_RS08870	COG1684	flagellar biosynthetic protein fliR
M0696_RS08875	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M0696_RS08880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M0696_RS08885	COG1419	protein localization to endoplasmic reticulum
M0696_RS08890	COG0455	bacterial-type flagellum organization
M0696_RS08895	COG2201	protein-glutamate methylesterase activity
M0696_RS08900	COG2198	Histidine kinase
M0696_RS08900	COG0643	Histidine kinase
M0696_RS08905	COG0835	chemotaxis
M0696_RS08910	COG1776	CheC inhibitor of MCP methylation
M0696_RS08915	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
M0696_RS08920	COG1191	sigma factor activity
M0696_RS08930	COG0052	Belongs to the universal ribosomal protein uS2 family
M0696_RS08935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M0696_RS08940	COG0528	UMP kinase activity
M0696_RS08945	COG0233	cytoplasmic translational termination
M0696_RS08950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M0696_RS08955	COG4589	Belongs to the CDS family
M0696_RS08960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M0696_RS08965	COG0750	zinc metalloprotease
M0696_RS08970	COG0442	prolyl-tRNA aminoacylation
M0696_RS08975	COG2176	DNA-directed DNA polymerase activity
M0696_RS08980	COG0779	Required for maturation of 30S ribosomal subunits
M0696_RS08985	COG0195	Participates in both transcription termination and antitermination
M0696_RS08990	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M0696_RS08995	COG1358	cellular component organization or biogenesis
M0696_RS09000	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
M0696_RS09005	COG1550	Protein conserved in bacteria
M0696_RS09010	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
M0696_RS09015	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M0696_RS09020	COG0196	riboflavin kinase activity
M0696_RS09030	COG1185	polyribonucleotide nucleotidyltransferase activity
M0696_RS09035	COG0726	polysaccharide deacetylase
M0696_RS09040	COG0612	Peptidase, M16
M0696_RS09045	COG1873	PFAM PRC-barrel domain
M0696_RS09050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M0696_RS09055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M0696_RS09060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
M0696_RS09065	COG0527	aspartate kinase activity
M0696_RS09070	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M0696_RS09075	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
M0696_RS09080	COG0740	serine-type endopeptidase activity
M0696_RS09090	COG1674	ftsk spoiiie
M0696_RS09090	COG4980	gas vesicle protein
M0696_RS09095	COG2188	Transcriptional regulator
M0696_RS09100	COG2814	Major facilitator Superfamily
M0696_RS09105	COG0612	Peptidase, M16
M0696_RS09110	COG0612	Peptidase, M16
M0696_RS09115	COG0300	oxidoreductase activity
M0696_RS09130	COG1426	Protein conserved in bacteria
M0696_RS09135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M0696_RS09140	COG1058	Belongs to the CinA family
M0696_RS09140	COG1546	Belongs to the CinA family
M0696_RS09145	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M0696_RS09150	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_RS09155	COG1418	mRNA catabolic process
M0696_RS09160	COG1692	metallophosphoesterase
M0696_RS09165	COG2359	stage V sporulation protein S
M0696_RS09170	COG1063	alcohol dehydrogenase
M0696_RS09175	COG0156	8-amino-7-oxononanoate synthase activity
M0696_RS09180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M0696_RS09185	COG4550	Control of competence regulator ComK, YlbF/YmcA
M0696_RS09195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
M0696_RS09200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M0696_RS09215	COG3226	Transcriptional regulator
M0696_RS09220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS09230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_RS09235	COG3321	synthase
M0696_RS09240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M0696_RS09240	COG2070	2-Nitropropane dioxygenase
M0696_RS09245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS09250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M0696_RS09255	COG3425	synthase
M0696_RS09260	COG1024	Enoyl-CoA hydratase
M0696_RS09265	COG1024	Enoyl-CoA hydratase
M0696_RS09270	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS09270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS09270	COG3321	synthase
M0696_RS09270	COG0300	oxidoreductase activity
M0696_RS09275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS09275	COG0300	oxidoreductase activity
M0696_RS09275	COG3321	synthase
M0696_RS09275	COG4221	oxidoreductase activity
M0696_RS09280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_RS09280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09280	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS09280	COG3321	synthase
M0696_RS09280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS09285	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS09285	COG4221	oxidoreductase activity
M0696_RS09285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09285	COG3321	synthase
M0696_RS09290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS09290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M0696_RS09290	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M0696_RS09290	COG3321	synthase
M0696_RS09295	COG2124	cytochrome p450
M0696_RS09305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS09310	COG1404	Belongs to the peptidase S8 family
M0696_RS09320	COG4195	phage-related replication protein
M0696_RS09325	COG1764	response to oxidative stress
M0696_RS09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
M0696_RS09355	COG1923	regulation of RNA biosynthetic process
M0696_RS09370	COG1780	Probably involved in ribonucleotide reductase function
M0696_RS09375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M0696_RS09380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M0696_RS09385	COG4112	unkown
M0696_RS09390	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS09395	COG0464	growth
M0696_RS09400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M0696_RS09405	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
M0696_RS09410	COG0789	Transcriptional regulator
M0696_RS09415	COG0174	glutamine synthetase
M0696_RS09440	COG3403	YqcI/YcgG family
M0696_RS09445	COG0135	phosphoribosylanthranilate isomerase activity
M0696_RS09460	COG2273	Hydrolase Family 16
M0696_RS09485	COG0726	polysaccharide deacetylase
M0696_RS09490	COG2211	Major facilitator Superfamily
M0696_RS09495	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_RS09505	COG2115	Belongs to the xylose isomerase family
M0696_RS09510	COG1070	Carbohydrate kinase
M0696_RS09515	COG1525	nuclease
M0696_RS09525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M0696_RS09535	COG0756	dUTP diphosphatase activity
M0696_RS09585	COG3832	glyoxalase III activity
M0696_RS09600	COG2059	Chromate
M0696_RS09605	COG0697	spore germination
M0696_RS09610	COG0531	amino acid
M0696_RS09640	COG4195	phage-related replication protein
M0696_RS09650	COG0346	lactoylglutathione lyase activity
M0696_RS09655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M0696_RS09660	COG1388	LysM domain
M0696_RS09665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_RS09670	COG4224	UPF0291 protein
M0696_RS09675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M0696_RS09685	COG3763	UPF0154 protein
M0696_RS09695	COG0785	Cytochrome C biogenesis protein
M0696_RS09700	COG2201	protein-glutamate methylesterase activity
M0696_RS09705	COG4846	Membrane protein involved in cytochrome C biogenesis
M0696_RS09715	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_RS09730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M0696_RS09735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS09755	COG0824	Thioesterase
M0696_RS09765	COG4841	protein insertion into membrane
M0696_RS09770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M0696_RS09775	COG1832	CoA-binding protein
M0696_RS09780	COG0187	DNA topoisomerase II activity
M0696_RS09785	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
M0696_RS09795	COG1115	amino acid carrier protein
M0696_RS09800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
M0696_RS09810	COG5520	Belongs to the glycosyl hydrolase 30 family
M0696_RS09815	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_RS09820	COG2246	polysaccharide biosynthetic process
M0696_RS09825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_RS09830	COG0586	Pfam SNARE associated Golgi protein
M0696_RS09835	COG2404	hydrolase activity, acting on ester bonds
M0696_RS09840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M0696_RS09845	COG1024	Enoyl-CoA hydratase
M0696_RS09850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M0696_RS09855	COG0511	ligase activity, forming carbon-carbon bonds
M0696_RS09860	COG0439	Biotin carboxylase
M0696_RS09865	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS09870	COG1960	acyl-CoA dehydrogenase activity
M0696_RS09880	COG1309	transcriptional regulator
M0696_RS09890	COG1649	PFAM Uncharacterised BCR, COG1649
M0696_RS09900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M0696_RS09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS09925	COG2027	D-alanyl-D-alanine carboxypeptidase
M0696_RS09930	COG2017	converts alpha-aldose to the beta-anomer
M0696_RS09935	COG0534	Mate efflux family protein
M0696_RS09950	COG0582	viral genome integration into host DNA
M0696_RS09955	COG0166	Belongs to the GPI family
M0696_RS09960	COG0405	Gamma-glutamyltransferase
M0696_RS09965	COG0583	DNA-binding transcription factor activity
M0696_RS09970	COG0604	alcohol dehydrogenase
M0696_RS09975	COG0493	'glutamate synthase
M0696_RS09980	COG0069	glutamate synthase activity
M0696_RS09980	COG0070	glutamate synthase
M0696_RS09980	COG0067	glutamate synthase
M0696_RS09985	COG0583	DNA-binding transcription factor activity
M0696_RS09990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M0696_RS10010	COG0300	oxidoreductase activity
M0696_RS10015	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M0696_RS10025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS10030	COG2814	Major facilitator Superfamily
M0696_RS10035	COG1070	Carbohydrate kinase
M0696_RS10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M0696_RS10045	COG0243	molybdopterin cofactor binding
M0696_RS10055	COG1082	Xylose isomerase domain protein TIM barrel
M0696_RS10075	COG2368	4-hydroxyphenylacetate
M0696_RS10080	COG4305	rare lipoprotein A
M0696_RS10085	COG3619	membrane
M0696_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS10110	COG2135	peptidase activity
M0696_RS10145	COG2720	vancomycin resistance protein
M0696_RS10155	COG3655	Transcriptional regulator
M0696_RS10160	COG3739	integral membrane protein
M0696_RS10165	COG0583	DNA-binding transcription factor activity
M0696_RS10170	COG0697	spore germination
M0696_RS10190	COG0693	protein deglycase activity
M0696_RS10195	COG2367	Beta-lactamase
M0696_RS10205	COG3397	chitin binding
M0696_RS10210	COG2318	DinB family
M0696_RS10215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M0696_RS10220	COG3848	Pyruvate phosphate dikinase
M0696_RS10220	COG0574	Belongs to the PEP-utilizing enzyme family
M0696_RS10250	COG1231	oxidoreductase activity
M0696_RS10255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_RS10260	COG0662	Cupin 2, conserved barrel domain protein
M0696_RS10260	COG2207	Transcriptional regulator
M0696_RS10265	COG0456	acetyltransferase
M0696_RS10270	COG1309	transcriptional regulator
M0696_RS10275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS10280	COG3708	Transcriptional regulator
M0696_RS10285	COG2378	regulation of single-species biofilm formation
M0696_RS10295	COG0640	Transcriptional regulator
M0696_RS10300	COG0741	lytic transglycosylase activity
M0696_RS10305	COG2322	membrane
M0696_RS10325	COG3239	Fatty acid desaturase
M0696_RS10330	COG4585	Histidine kinase
M0696_RS10335	COG2197	response regulator
M0696_RS10340	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS10345	COG3584	3D domain protein
M0696_RS10345	COG1388	LysM domain
M0696_RS10360	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M0696_RS10365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_RS10385	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS10390	COG1657	PFAM Prenyltransferase squalene oxidase
M0696_RS10395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M0696_RS10400	COG0733	neurotransmitter:sodium symporter activity
M0696_RS10405	COG0385	Bile acid
M0696_RS10410	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_RS10415	COG0567	Dehydrogenase, E1 component
M0696_RS10420	COG4548	von Willebrand factor, type A
M0696_RS10425	COG0714	Associated with various cellular activities
M0696_RS10430	COG2032	superoxide dismutase activity
M0696_RS10435	COG1388	LysM domain
M0696_RS10435	COG0791	NLP P60 protein
M0696_RS10440	COG1819	glycosyl
M0696_RS10445	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M0696_RS10450	COG0534	Mate efflux family protein
M0696_RS10455	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS10460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_RS10465	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_RS10475	COG2962	Rard protein
M0696_RS10490	COG2610	gluconate transmembrane transporter activity
M0696_RS10495	COG1942	4-Oxalocrotonate Tautomerase
M0696_RS10505	COG1733	regulation of RNA biosynthetic process
M0696_RS10510	COG0778	Nitroreductase
M0696_RS10515	COG0400	carboxylic ester hydrolase activity
M0696_RS10520	COG0346	lactoylglutathione lyase activity
M0696_RS10530	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS10535	COG0793	Belongs to the peptidase S41A family
M0696_RS10535	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS10540	COG2226	methyltransferase
M0696_RS10550	COG1876	peptidase activity
M0696_RS10555	COG0813	purine-nucleoside phosphorylase activity
M0696_RS10570	COG0671	phosphoesterase, PA-phosphatase related
M0696_RS10590	COG4479	Belongs to the UPF0346 family
M0696_RS10600	COG1509	lysine 2,3-aminomutase activity
M0696_RS10605	COG0456	acetyltransferase
M0696_RS10610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_RS10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M0696_RS10620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M0696_RS10625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_RS10635	COG0456	acetyltransferase
M0696_RS10640	COG0463	Glycosyl transferase, family 2
M0696_RS10655	COG4641	Protein conserved in bacteria
M0696_RS10660	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
M0696_RS10665	COG1086	Polysaccharide biosynthesis protein
M0696_RS10675	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M0696_RS10680	COG1846	Transcriptional regulator
M0696_RS10685	COG0534	Mate efflux family protein
M0696_RS10695	COG4698	Protein conserved in bacteria
M0696_RS10700	COG2755	lipolytic protein G-D-S-L family
M0696_RS10705	COG1999	signal sequence binding
M0696_RS10715	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M0696_RS10720	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M0696_RS10725	COG1272	protein, Hemolysin III
M0696_RS10730	COG0204	Acyl-transferase
M0696_RS10735	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_RS10745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M0696_RS10755	COG2521	methyltransferase
M0696_RS10755	COG2136	Putative SAM-dependent methyltransferase
M0696_RS10765	COG0129	dihydroxy-acid dehydratase activity
M0696_RS10770	COG1413	lyase activity
M0696_RS10775	COG1418	mRNA catabolic process
M0696_RS10780	COG0386	Belongs to the glutathione peroxidase family
M0696_RS10785	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
M0696_RS10790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M0696_RS10800	COG1278	Cold shock
M0696_RS10820	COG0328	RNA-DNA hybrid ribonuclease activity
M0696_RS10825	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M0696_RS10830	COG0328	RNA-DNA hybrid ribonuclease activity
M0696_RS10840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_RS10855	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M0696_RS10865	COG1755	Isoprenylcysteine carboxyl methyltransferase
M0696_RS10870	COG3424	synthase
M0696_RS10875	COG2233	PERMEase
M0696_RS10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_RS10885	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
M0696_RS10895	COG0800	Aldolase
M0696_RS10900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_RS10905	COG1609	Transcriptional regulator
M0696_RS10910	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
M0696_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS10920	COG1199	ATP-dependent helicase activity
M0696_RS10935	COG0116	Belongs to the methyltransferase superfamily
M0696_RS10950	COG4474	Belongs to the UPF0398 family
M0696_RS10965	COG3359	exonuclease
M0696_RS10970	COG1111	helicase
M0696_RS10970	COG1205	dead DEAH box helicase
M0696_RS10975	COG2190	(PTS) system
M0696_RS10980	COG0071	Belongs to the small heat shock protein (HSP20) family
M0696_RS11015	COG3331	DNA recombination
M0696_RS11020	COG4499	WXG100 protein secretion system (Wss), protein YukC
M0696_RS11020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_RS11030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M0696_RS11035	COG3935	DnaD domain protein
M0696_RS11040	COG0017	Asparaginyl-tRNA synthetase
M0696_RS11045	COG0436	Aminotransferase
M0696_RS11050	COG5353	protein conserved in bacteria
M0696_RS11060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M0696_RS11060	COG1199	ATP-dependent helicase activity
M0696_RS11065	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
M0696_RS11070	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
M0696_RS11075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
M0696_RS11085	COG0617	tRNA 3'-terminal CCA addition
M0696_RS11090	COG0438	transferase activity, transferring glycosyl groups
M0696_RS11095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
M0696_RS11100	COG1803	Methylglyoxal synthase
M0696_RS11105	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
M0696_RS11110	COG1694	Mazg nucleotide pyrophosphohydrolase
M0696_RS11115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS11125	COG4347	Protein of unknown function (DUF1405)
M0696_RS11130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M0696_RS11130	COG2010	Cytochrome c
M0696_RS11135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M0696_RS11140	COG0723	plastoquinol--plastocyanin reductase activity
M0696_RS11150	COG5582	Belongs to the UPF0302 family
M0696_RS11155	COG0457	Tetratricopeptide repeat
M0696_RS11160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M0696_RS11165	COG0287	Prephenate dehydrogenase
M0696_RS11170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M0696_RS11175	COG0159	tryptophan synthase activity
M0696_RS11180	COG0133	tryptophan synthase activity
M0696_RS11185	COG0135	phosphoribosylanthranilate isomerase activity
M0696_RS11195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M0696_RS11200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M0696_RS11205	COG4401	Chorismate mutase type I
M0696_RS11210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
M0696_RS11215	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M0696_RS11220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M0696_RS11225	COG0105	UTP biosynthetic process
M0696_RS11230	COG0142	geranyltranstransferase activity
M0696_RS11235	COG2226	methyltransferase
M0696_RS11240	COG0142	geranyltranstransferase activity
M0696_RS11250	COG0302	gtp cyclohydrolase
M0696_RS11255	COG0776	regulation of translation
M0696_RS11260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
M0696_RS11275	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
M0696_RS11280	COG1160	GTP binding
M0696_RS11305	COG1304	FMN binding
M0696_RS11310	COG0539	negative regulation of cytoplasmic translation
M0696_RS11315	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
M0696_RS11325	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
M0696_RS11330	COG2959	enzyme of heme biosynthesis
M0696_RS11335	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS11335	COG3773	Cell wall hydrolase
M0696_RS11340	COG2339	peptidase activity
M0696_RS11345	COG0492	ferredoxin-NADP+ reductase activity
M0696_RS11350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_RS11355	COG4862	establishment of competence for transformation
M0696_RS11360	COG1408	metallophosphoesterase
M0696_RS11370	COG1388	LysM domain
M0696_RS11375	COG1266	CAAX protease self-immunity
M0696_RS11380	COG0514	ATP-dependent DNA helicase (RecQ)
M0696_RS11385	COG4955	Helix-turn-helix domain
M0696_RS11390	COG1141	Ferredoxin
M0696_RS11395	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M0696_RS11400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M0696_RS11405	COG0710	3-dehydroquinate dehydratase activity
M0696_RS11415	COG1595	DNA-templated transcription, initiation
M0696_RS11420	COG5002	protein histidine kinase activity
M0696_RS11425	COG0745	RESPONSE REGULATOR receiver
M0696_RS11430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M0696_RS11435	COG1333	cytochrome c biogenesis protein
M0696_RS11440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS11445	COG1187	pseudouridine synthase activity
M0696_RS11450	COG0700	Nucleoside recognition
M0696_RS11455	COG2715	membrane protein required for spore maturation
M0696_RS11460	COG1686	Belongs to the peptidase S11 family
M0696_RS11470	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M0696_RS11475	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M0696_RS11480	COG1547	Domain of unknown function (DUF309)
M0696_RS11485	COG0456	acetyltransferase
M0696_RS11490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
M0696_RS11495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M0696_RS11495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M0696_RS11500	COG0307	riboflavin synthase, alpha
M0696_RS11505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M0696_RS11505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M0696_RS11515	COG0681	Belongs to the peptidase S26 family
M0696_RS11530	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
M0696_RS11540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M0696_RS11545	COG4086	secreted protein
M0696_RS11550	COG0019	diaminopimelate decarboxylase activity
M0696_RS11555	COG0697	spore germination
M0696_RS11570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M0696_RS11590	COG1191	sigma factor activity
M0696_RS11595	COG2172	sigma factor antagonist activity
M0696_RS11600	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS11605	COG1686	Belongs to the peptidase S11 family
M0696_RS11610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
M0696_RS11615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
M0696_RS11620	COG4974	Belongs to the 'phage' integrase family
M0696_RS11630	COG0735	belongs to the Fur family
M0696_RS11635	COG1300	Membrane
M0696_RS11645	COG0281	malic enzyme
M0696_RS11650	COG1757	Na H antiporter
M0696_RS11655	COG1027	Aspartate ammonia-lyase
M0696_RS11660	COG0252	asparaginase activity
M0696_RS11665	COG1396	sequence-specific DNA binding
M0696_RS11670	COG1379	DNA repair
M0696_RS11675	COG0494	nUDIX hydrolase
M0696_RS11685	COG0667	Aldo Keto reductase
M0696_RS11695	COG1073	alpha beta
M0696_RS11700	COG0772	Belongs to the SEDS family
M0696_RS11705	COG0772	Belongs to the SEDS family
M0696_RS11710	COG3339	Conserved Protein
M0696_RS11720	COG4918	Iron-sulphur cluster biosynthesis
M0696_RS11725	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M0696_RS11725	COG0456	acetyltransferase
M0696_RS11730	COG2329	Antibiotic biosynthesis monooxygenase
M0696_RS11735	COG0456	acetyltransferase
M0696_RS11745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M0696_RS11755	COG2211	Major facilitator Superfamily
M0696_RS11765	COG0346	lactoylglutathione lyase activity
M0696_RS11770	COG1072	(Pantothenic acid kinase))
M0696_RS11775	COG3048	D-serine ammonia-lyase activity
M0696_RS11780	COG0300	oxidoreductase activity
M0696_RS11785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS11790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_RS11795	COG4187	Peptidase family M20/M25/M40
M0696_RS11800	COG1902	pentaerythritol trinitrate reductase activity
M0696_RS11805	COG0596	Alpha beta hydrolase
M0696_RS11815	COG1234	tRNA 3'-trailer cleavage
M0696_RS11820	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
M0696_RS11825	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M0696_RS11830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M0696_RS11840	COG0706	membrane insertase activity
M0696_RS11845	COG3361	conserved protein (COG2071)
M0696_RS11850	COG2195	Cleaves the N-terminal amino acid of tripeptides
M0696_RS11855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M0696_RS11860	COG0346	lactoylglutathione lyase activity
M0696_RS11870	COG1376	ErfK ybiS ycfS ynhG family protein
M0696_RS11875	COG4129	membrane
M0696_RS11880	COG1126	abc transporter atp-binding protein
M0696_RS11885	COG0765	amino acid transport
M0696_RS11890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_RS11900	COG1597	lipid kinase activity
M0696_RS11905	COG2814	Major facilitator Superfamily
M0696_RS11910	COG4978	Transcriptional regulator
M0696_RS11910	COG0789	Transcriptional regulator
M0696_RS11915	COG0508	dehydrogenase complex catalyzes the overall conversion of
M0696_RS11920	COG0022	dehydrogenase e1 component
M0696_RS11925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M0696_RS11930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M0696_RS11935	COG3426	butyrate kinase activity
M0696_RS11940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_RS11945	COG0280	phosphate acetyltransferase
M0696_RS11950	COG3829	transcription factor binding
M0696_RS11950	COG3290	protein histidine kinase activity
M0696_RS11960	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
M0696_RS11965	COG2079	MmgE PrpD family protein
M0696_RS11970	COG0372	Belongs to the citrate synthase family
M0696_RS11975	COG1960	acyl-CoA dehydrogenase activity
M0696_RS11980	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_RS11985	COG0183	Belongs to the thiolase family
M0696_RS11990	COG0584	glycerophosphoryl diester phosphodiesterase
M0696_RS11995	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS12005	COG1902	pentaerythritol trinitrate reductase activity
M0696_RS12010	COG0745	RESPONSE REGULATOR receiver
M0696_RS12015	COG0750	zinc metalloprotease
M0696_RS12020	COG0497	DNA recombination
M0696_RS12025	COG1438	arginine binding
M0696_RS12030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M0696_RS12035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
M0696_RS12040	COG0142	geranyltranstransferase activity
M0696_RS12045	COG1722	exodeoxyribonuclease VII activity
M0696_RS12050	COG1570	exodeoxyribonuclease VII activity
M0696_RS12055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M0696_RS12060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M0696_RS12065	COG1302	Protein conserved in bacteria
M0696_RS12070	COG0439	Biotin carboxylase
M0696_RS12075	COG0511	ligase activity, forming carbon-carbon bonds
M0696_RS12115	COG3854	ATPases associated with a variety of cellular activities
M0696_RS12125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
M0696_RS12130	COG0006	proline dipeptidase activity
M0696_RS12135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
M0696_RS12145	COG3872	metal-dependent enzyme
M0696_RS12155	COG1752	Esterase of the alpha-beta hydrolase superfamily
M0696_RS12160	COG1321	iron dependent repressor
M0696_RS12165	COG0095	Lipoate-protein ligase
M0696_RS12170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_RS12175	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M0696_RS12180	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M0696_RS12185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
M0696_RS12190	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M0696_RS12205	COG1396	sequence-specific DNA binding
M0696_RS12215	COG0681	Belongs to the peptidase S26 family
M0696_RS12240	COG4940	Competence protein ComGF
M0696_RS12250	COG4970	Tfp pilus assembly protein FimT
M0696_RS12255	COG4537	Required for transformation and DNA binding
M0696_RS12260	COG1459	type II secretion system
M0696_RS12265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M0696_RS12270	COG0517	IMP dehydrogenase activity
M0696_RS12275	COG0598	Magnesium transport protein CorA
M0696_RS12280	COG1253	flavin adenine dinucleotide binding
M0696_RS12285	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS12295	COG1393	Belongs to the ArsC family
M0696_RS12305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS12315	COG0011	TIGRFAM Protein of
M0696_RS12325	COG2866	Carboxypeptidase
M0696_RS12330	COG1368	sulfuric ester hydrolase activity
M0696_RS12335	COG1940	carbohydrate kinase activity
M0696_RS12345	COG0457	Tetratricopeptide repeat
M0696_RS12345	COG0705	Rhomboid family
M0696_RS12355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M0696_RS12365	COG0438	transferase activity, transferring glycosyl groups
M0696_RS12380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M0696_RS12385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_RS12390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M0696_RS12395	COG0581	inorganic phosphate transmembrane transporter activity
M0696_RS12400	COG0573	inorganic phosphate transmembrane transporter activity
M0696_RS12405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M0696_RS12410	COG0768	penicillin binding
M0696_RS12415	COG0477	Major facilitator Superfamily
M0696_RS12420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M0696_RS12425	COG2839	Protein conserved in bacteria
M0696_RS12430	COG5521	maltodextrose utilization protein MalA
M0696_RS12440	COG1388	LysM domain
M0696_RS12445	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
M0696_RS12450	COG4709	membrane
M0696_RS12455	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
M0696_RS12460	COG0735	belongs to the Fur family
M0696_RS12465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS12475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
M0696_RS12480	COG0513	Belongs to the DEAD box helicase family
M0696_RS12490	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
M0696_RS12495	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M0696_RS12500	COG2384	SAM-dependent methyltransferase
M0696_RS12505	COG2010	Cytochrome c
M0696_RS12510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M0696_RS12515	COG0358	DNA primase activity
M0696_RS12520	COG1671	Belongs to the UPF0178 family
M0696_RS12525	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
M0696_RS12530	COG0517	IMP dehydrogenase activity
M0696_RS12535	COG0751	glycine-tRNA ligase activity
M0696_RS12540	COG0752	glycyl-tRNA synthetase alpha subunit
M0696_RS12545	COG1381	Involved in DNA repair and RecF pathway recombination
M0696_RS12555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M0696_RS12560	COG0295	cytidine deaminase activity
M0696_RS12565	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M0696_RS12570	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
M0696_RS12575	COG1480	7TM receptor with intracellular HD hydrolase
M0696_RS12580	COG1702	phosphate starvation-inducible protein PhoH
M0696_RS12585	COG0561	phosphatase activity
M0696_RS12600	COG4864	UPF0365 protein
M0696_RS12605	COG1030	water channel activity
M0696_RS12610	COG1610	YqeY-like protein
M0696_RS12620	COG1283	sodium-dependent phosphate transmembrane transporter activity
M0696_RS12625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M0696_RS12630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M0696_RS12635	COG2264	protein methyltransferase activity
M0696_RS12640	COG0484	heat shock protein binding
M0696_RS12650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M0696_RS12655	COG1420	regulation of RNA biosynthetic process
M0696_RS12660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M0696_RS12665	COG0481	GTPase activity
M0696_RS12675	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS12680	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
M0696_RS12685	COG0268	Binds directly to 16S ribosomal RNA
M0696_RS12690	COG1466	dna polymerase III delta subunit
M0696_RS12705	COG0658	competence protein
M0696_RS12705	COG2333	competence protein COMEC
M0696_RS12710	COG2131	deaminase
M0696_RS12715	COG1596	polysaccharide export
M0696_RS12715	COG1555	photosystem II stabilization
M0696_RS12720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M0696_RS12725	COG2226	methyltransferase
M0696_RS12730	COG0799	negative regulation of ribosome biogenesis
M0696_RS12735	COG1713	HD superfamily hydrolase involved in NAD metabolism
M0696_RS12740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
M0696_RS12745	COG1534	Rna-binding protein
M0696_RS12750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M0696_RS12755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M0696_RS12760	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M0696_RS12770	COG2755	lipolytic protein G-D-S-L family
M0696_RS12775	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS12775	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_RS12780	COG0398	Pfam SNARE associated Golgi protein
M0696_RS12785	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
M0696_RS12795	COG3209	COG3209 Rhs family protein
M0696_RS12805	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS12830	COG1174	glycine betaine transport
M0696_RS12835	COG1125	glycine betaine transport
M0696_RS12835	COG0517	IMP dehydrogenase activity
M0696_RS12840	COG3321	synthase
M0696_RS12840	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS12840	COG0604	alcohol dehydrogenase
M0696_RS12845	COG1733	regulation of RNA biosynthetic process
M0696_RS12850	COG0457	Tetratricopeptide repeat
M0696_RS12860	COG5444	nuclease activity
M0696_RS12870	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_RS12870	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS12875	COG4824	toxin secretion phage lysis holin
M0696_RS12905	COG3778	Protein conserved in bacteria
M0696_RS12910	COG3299	homolog of phage Mu protein gp47
M0696_RS12915	COG3628	GPW Gp25 family protein
M0696_RS12925	COG4193	domain, Protein
M0696_RS12930	COG1652	LysM domain
M0696_RS12935	COG3953	SLT domain
M0696_RS12935	COG5280	Phage tail tape measure protein TP901
M0696_RS13000	COG4653	Phage capsid family
M0696_RS13005	COG0338	D12 class N6 adenine-specific DNA methyltransferase
M0696_RS13015	COG2369	cell adhesion
M0696_RS13020	COG5518	Phage portal protein
M0696_RS13025	COG1783	phage Terminase large subunit
M0696_RS13030	COG5484	DNA packaging
M0696_RS13055	COG3677	Transposase
M0696_RS13080	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
M0696_RS13090	COG1484	DNA-dependent DNA replication
M0696_RS13095	COG3935	DnaD domain protein
M0696_RS13100	COG3723	Recombinational DNA repair protein, rece pathway
M0696_RS13105	COG5377	YqaJ viral recombinase family
M0696_RS13140	COG3620	sequence-specific DNA binding
M0696_RS13155	COG2856	Zn peptidase
M0696_RS13175	COG2323	membrane
M0696_RS13180	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
M0696_RS13185	COG0730	response to heat
M0696_RS13190	COG0425	Belongs to the sulfur carrier protein TusA family
M0696_RS13195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_RS13195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS13200	COG2210	Belongs to the sulfur carrier protein TusA family
M0696_RS13205	COG0425	Belongs to the sulfur carrier protein TusA family
M0696_RS13205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_RS13210	COG1054	Belongs to the UPF0176 family
M0696_RS13215	COG2210	Belongs to the sulfur carrier protein TusA family
M0696_RS13220	COG1937	Protein conserved in bacteria
M0696_RS13230	COG0662	Cupin 2, conserved barrel domain protein
M0696_RS13240	COG0604	alcohol dehydrogenase
M0696_RS13250	COG2315	Protein conserved in bacteria
M0696_RS13255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_RS13270	COG0583	DNA-binding transcription factor activity
M0696_RS13275	COG0457	Tetratricopeptide repeat
M0696_RS13290	COG5444	nuclease activity
M0696_RS13300	COG5632	N-Acetylmuramoyl-L-alanine amidase
M0696_RS13300	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS13305	COG4824	toxin secretion phage lysis holin
M0696_RS13330	COG2856	Zn peptidase
M0696_RS13345	COG0789	Transcriptional regulator
M0696_RS13345	COG4978	Transcriptional regulator
M0696_RS13350	COG2814	Major facilitator Superfamily
M0696_RS13355	COG0456	acetyltransferase
M0696_RS13360	COG1253	flavin adenine dinucleotide binding
M0696_RS13380	COG0789	Transcriptional regulator
M0696_RS13380	COG4978	Transcriptional regulator
M0696_RS13390	COG2315	Protein conserved in bacteria
M0696_RS13400	COG3443	Belongs to the bacterial solute-binding protein 9 family
M0696_RS13405	COG4991	sh3 domain protein
M0696_RS13410	COG4991	sh3 domain protein
M0696_RS13420	COG5577	PFAM Coat F domain
M0696_RS13425	COG1063	alcohol dehydrogenase
M0696_RS13435	COG5577	PFAM Coat F domain
M0696_RS13445	COG0789	Transcriptional regulator
M0696_RS13450	COG0789	Transcriptional regulator
M0696_RS13465	COG1064	alcohol dehydrogenase
M0696_RS13470	COG0693	protein deglycase activity
M0696_RS13475	COG1621	beta-fructofuranosidase activity
M0696_RS13485	COG3716	PTS system mannose fructose sorbose family IID component
M0696_RS13490	COG3715	PTS system
M0696_RS13495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS13500	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS13505	COG3933	PFAM sigma-54 factor interaction domain-containing protein
M0696_RS13505	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
M0696_RS13525	COG1113	amino acid transport
M0696_RS13530	COG1280	lysine exporter protein (LysE YggA)
M0696_RS13535	COG1378	Sugar-specific transcriptional regulator TrmB
M0696_RS13540	COG1595	DNA-templated transcription, initiation
M0696_RS13550	COG2755	lipolytic protein G-D-S-L family
M0696_RS13550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M0696_RS13560	COG2124	cytochrome p450
M0696_RS13560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M0696_RS13565	COG1309	transcriptional regulator
M0696_RS13570	COG2226	methyltransferase
M0696_RS13585	COG2116	formate transmembrane transporter activity
M0696_RS13590	COG5609	conserved protein (DUF2294)
M0696_RS13595	COG3383	formate dehydrogenase (NAD+) activity
M0696_RS13600	COG2427	Protein of unknown function (DUF1641)
M0696_RS13610	COG0626	cystathionine gamma-synthase activity
M0696_RS13615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_RS13620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M0696_RS13625	COG2226	methyltransferase
M0696_RS13640	COG0768	penicillin binding
M0696_RS13645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M0696_RS13650	COG0572	uridine kinase
M0696_RS13655	COG0826	peptidase U32
M0696_RS13660	COG0826	peptidase U32
M0696_RS13665	COG4122	O-methyltransferase activity
M0696_RS13670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M0696_RS13675	COG3906	Belongs to the UPF0473 family
M0696_RS13680	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M0696_RS13685	COG4472	Bacterial protein of unknown function (DUF965)
M0696_RS13690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M0696_RS13695	COG0628	permease
M0696_RS13710	COG3881	PFAM PRC-barrel domain
M0696_RS13715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M0696_RS13720	COG0457	Tetratricopeptide repeat
M0696_RS13725	COG0482	sulfurtransferase activity
M0696_RS13730	COG1104	cysteine desulfurase activity
M0696_RS13735	COG1959	2 iron, 2 sulfur cluster binding
M0696_RS13740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M0696_RS13745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M0696_RS13755	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
M0696_RS13760	COG0124	histidyl-tRNA synthetase
M0696_RS13770	COG3103	Sh3 type 3 domain protein
M0696_RS13770	COG4991	sh3 domain protein
M0696_RS13770	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS13775	COG1490	D-aminoacyl-tRNA deacylase activity
M0696_RS13780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M0696_RS13785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M0696_RS13790	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M0696_RS13790	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M0696_RS13795	COG5416	Lipopolysaccharide assembly protein A domain
M0696_RS13800	COG0490	domain, Protein
M0696_RS13805	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M0696_RS13805	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M0696_RS13815	COG2244	polysaccharide biosynthetic process
M0696_RS13820	COG2323	membrane
M0696_RS13830	COG1862	Preprotein translocase
M0696_RS13835	COG0343	queuine tRNA-ribosyltransferase activity
M0696_RS13840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
M0696_RS13850	COG2255	four-way junction helicase activity
M0696_RS13855	COG0632	four-way junction helicase activity
M0696_RS13865	COG2814	Major facilitator Superfamily
M0696_RS13870	COG0673	inositol 2-dehydrogenase activity
M0696_RS13875	COG2112	serine threonine protein kinase
M0696_RS13885	COG1115	amino acid carrier protein
M0696_RS13890	COG0217	transcriptional regulatory protein
M0696_RS13900	COG1388	LysM domain
M0696_RS13905	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M0696_RS13910	COG0157	Belongs to the NadC ModD family
M0696_RS13915	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
M0696_RS13920	COG1104	cysteine desulfurase activity
M0696_RS13925	COG1827	regulation of RNA biosynthetic process
M0696_RS13930	COG0077	Prephenate dehydratase
M0696_RS13935	COG4492	Belongs to the UPF0735 family
M0696_RS13940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M0696_RS13945	COG3290	protein histidine kinase activity
M0696_RS13955	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M0696_RS13960	COG2868	ribosomal protein
M0696_RS13965	COG0261	This protein binds to 23S rRNA in the presence of protein L20
M0696_RS13970	COG1994	Peptidase M50
M0696_RS13975	COG0739	heme binding
M0696_RS13980	COG2894	cell division
M0696_RS13985	COG0850	regulation of cytokinetic process
M0696_RS13990	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M0696_RS14000	COG1077	Cell shape determining protein MreB Mrl
M0696_RS14005	COG2003	Belongs to the UPF0758 family
M0696_RS14010	COG0424	maF-like protein
M0696_RS14020	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M0696_RS14025	COG0285	dihydrofolate synthase activity
M0696_RS14030	COG0525	valine-tRNA ligase activity
M0696_RS14040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_RS14045	COG1388	LysM domain
M0696_RS14050	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M0696_RS14055	COG0113	porphobilinogen synthase activity
M0696_RS14060	COG1587	Uroporphyrinogen-III synthase
M0696_RS14065	COG0181	hydroxymethylbilane synthase activity
M0696_RS14070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M0696_RS14075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
M0696_RS14085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
M0696_RS14090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M0696_RS14095	COG0470	DNA polymerase III
M0696_RS14095	COG1067	ATP-dependent peptidase activity
M0696_RS14100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
M0696_RS14105	COG0544	peptidyl-prolyl cis-trans isomerase activity
M0696_RS14110	COG0457	Tetratricopeptide repeat
M0696_RS14110	COG1477	protein flavinylation
M0696_RS14115	COG0066	3-isopropylmalate dehydratase activity
M0696_RS14120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M0696_RS14125	COG0473	3-isopropylmalate dehydrogenase activity
M0696_RS14130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M0696_RS14135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M0696_RS14140	COG0440	acetolactate synthase activity
M0696_RS14145	COG0028	Belongs to the TPP enzyme family
M0696_RS14155	COG0454	-acetyltransferase
M0696_RS14160	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
M0696_RS14170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M0696_RS14185	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
M0696_RS14200	COG0622	Phosphoesterase
M0696_RS14205	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M0696_RS14210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
M0696_RS14215	COG5401	PFAM Sporulation and spore germination
M0696_RS14220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M0696_RS14225	COG1846	Transcriptional regulator
M0696_RS14230	COG2197	response regulator
M0696_RS14235	COG0824	Thioesterase
M0696_RS14240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M0696_RS14245	COG1053	succinate dehydrogenase
M0696_RS14250	COG2009	succinate dehydrogenase
M0696_RS14255	COG1719	4-vinyl reductase, 4VR
M0696_RS14260	COG0527	aspartate kinase activity
M0696_RS14265	COG0322	excinuclease ABC activity
M0696_RS14270	COG3118	belongs to the thioredoxin family
M0696_RS14275	COG3534	alpha-L-arabinofuranosidase
M0696_RS14280	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
M0696_RS14285	COG2086	electron transfer activity
M0696_RS14290	COG1024	Enoyl-CoA hydratase
M0696_RS14295	COG1309	transcriptional regulator
M0696_RS14300	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS14305	COG3766	membrane
M0696_RS14310	COG1193	negative regulation of DNA recombination
M0696_RS14315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M0696_RS14315	COG1796	DNA polymerase
M0696_RS14320	COG1286	toxin biosynthetic process
M0696_RS14325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
M0696_RS14330	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M0696_RS14335	COG0072	phenylalanine-tRNA ligase activity
M0696_RS14335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_RS14340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M0696_RS14350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M0696_RS14360	COG3835	regulator
M0696_RS14365	COG0277	FAD linked oxidase domain protein
M0696_RS14370	COG0247	lactate metabolic process
M0696_RS14375	COG0346	lactoylglutathione lyase activity
M0696_RS14385	COG1966	Carbon starvation protein
M0696_RS14390	COG3534	alpha-L-arabinofuranosidase
M0696_RS14395	COG0395	ABC-type sugar transport system, permease component
M0696_RS14400	COG1175	transmembrane transport
M0696_RS14405	COG1653	transport
M0696_RS14410	COG0371	Dehydrogenase
M0696_RS14415	COG0647	UMP catabolic process
M0696_RS14420	COG0235	Class ii aldolase
M0696_RS14425	COG1069	ribulokinase activity
M0696_RS14430	COG2160	L-arabinose isomerase activity
M0696_RS14435	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_RS14440	COG1363	Peptidase, m42
M0696_RS14450	COG3326	Membrane
M0696_RS14455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M0696_RS14460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
M0696_RS14465	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M0696_RS14475	COG1346	cytolysis
M0696_RS14480	COG1380	Effector of murein hydrolase LrgA
M0696_RS14485	COG3279	Response regulator of the LytR AlgR family
M0696_RS14490	COG3275	phosphorelay sensor kinase activity
M0696_RS14495	COG1011	Hydrolase
M0696_RS14500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M0696_RS14510	COG0398	Pfam SNARE associated Golgi protein
M0696_RS14515	COG1484	DNA-dependent DNA replication
M0696_RS14520	COG3611	Membrane attachment protein
M0696_RS14525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M0696_RS14530	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
M0696_RS14535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M0696_RS14540	COG1733	regulation of RNA biosynthetic process
M0696_RS14545	COG2814	Major facilitator Superfamily
M0696_RS14550	COG0656	L-ascorbic acid biosynthetic process
M0696_RS14555	COG0237	dephospho-CoA kinase activity
M0696_RS14560	COG1971	Probably functions as a manganese efflux pump
M0696_RS14565	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M0696_RS14570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_RS14570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M0696_RS14575	COG5002	protein histidine kinase activity
M0696_RS14580	COG0745	RESPONSE REGULATOR receiver
M0696_RS14585	COG0039	L-malate dehydrogenase activity
M0696_RS14590	COG0538	isocitrate dehydrogenase activity
M0696_RS14595	COG0372	Belongs to the citrate synthase family
M0696_RS14600	COG2707	UPF0756 membrane protein
M0696_RS14605	COG0628	permease
M0696_RS14610	COG3030	protein affecting phage T7 exclusion by the F plasmid
M0696_RS14615	COG0469	pyruvate kinase activity
M0696_RS14620	COG0205	6-phosphofructokinase activity
M0696_RS14625	COG0825	malonyl-CoA metabolic process
M0696_RS14630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
M0696_RS14635	COG0281	malic enzyme
M0696_RS14640	COG0587	DNA-directed DNA polymerase activity
M0696_RS14660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M0696_RS14670	COG4109	DRTGG domain
M0696_RS14675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
M0696_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS14685	COG0165	Argininosuccinate lyase
M0696_RS14690	COG0137	argininosuccinate synthase activity
M0696_RS14695	COG0521	Mo-molybdopterin cofactor biosynthetic process
M0696_RS14700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M0696_RS14705	COG0827	DNA restriction-modification system
M0696_RS14710	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
M0696_RS14715	COG3874	Sporulation protein YtfJ
M0696_RS14725	COG1714	RDD family
M0696_RS14730	COG0616	signal peptide processing
M0696_RS14735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M0696_RS14740	COG1574	metal-dependent hydrolase with the TIM-barrel fold
M0696_RS14745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M0696_RS14755	COG0301	tRNA thio-modification
M0696_RS14760	COG1104	cysteine desulfurase activity
M0696_RS14765	COG1114	Component of the transport system for branched-chain amino acids
M0696_RS14770	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
M0696_RS14775	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
M0696_RS14780	COG1309	transcriptional regulator
M0696_RS14785	COG1956	GAF domain-containing protein
M0696_RS14790	COG2199	diguanylate cyclase activity
M0696_RS14790	COG2203	Gaf domain
M0696_RS14795	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M0696_RS14800	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M0696_RS14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M0696_RS14810	COG0454	-acetyltransferase
M0696_RS14815	COG0517	IMP dehydrogenase activity
M0696_RS14820	COG0123	including yeast histone deacetylase and acetoin utilization protein
M0696_RS14830	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
M0696_RS14835	COG1609	Transcriptional regulator
M0696_RS14840	COG1605	Chorismate mutase
M0696_RS14840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M0696_RS14845	COG3118	belongs to the thioredoxin family
M0696_RS14850	COG4980	gas vesicle protein
M0696_RS14855	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
M0696_RS14860	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M0696_RS14865	COG1674	ftsk spoiiie
M0696_RS14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M0696_RS14875	COG4848	Belongs to the UPF0354 family
M0696_RS14880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS14895	COG1363	Peptidase, m42
M0696_RS14900	COG5584	Small secreted protein
M0696_RS14905	COG0281	malic enzyme
M0696_RS14910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS14915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M0696_RS14925	COG0510	thiamine kinase activity
M0696_RS14930	COG1523	belongs to the glycosyl hydrolase 13 family
M0696_RS14935	COG1597	lipid kinase activity
M0696_RS14945	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
M0696_RS14950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M0696_RS14955	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_RS14960	COG2252	PERMEase
M0696_RS14965	COG4473	ABC transporter
M0696_RS14970	COG1131	(ABC) transporter
M0696_RS14975	COG1349	DNA-binding transcription factor activity
M0696_RS14980	COG1187	pseudouridine synthase activity
M0696_RS14985	COG2244	polysaccharide biosynthetic process
M0696_RS14990	COG2081	HI0933 family
M0696_RS14995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M0696_RS15005	COG5578	integral membrane protein
M0696_RS15010	COG0673	inositol 2-dehydrogenase activity
M0696_RS15015	COG1653	transport
M0696_RS15020	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
M0696_RS15025	COG4209	transmembrane transport
M0696_RS15030	COG2207	Transcriptional regulator
M0696_RS15035	COG1653	transport
M0696_RS15040	COG0395	ABC-type sugar transport system, permease component
M0696_RS15045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_RS15050	COG2124	cytochrome p450
M0696_RS15055	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M0696_RS15065	COG0156	8-amino-7-oxononanoate synthase activity
M0696_RS15070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M0696_RS15085	COG1073	alpha beta
M0696_RS15090	COG1609	Transcriptional regulator
M0696_RS15095	COG1653	transport
M0696_RS15100	COG1175	transmembrane transport
M0696_RS15105	COG0395	ABC-type sugar transport system, permease component
M0696_RS15110	COG1486	melibiose metabolic process
M0696_RS15115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M0696_RS15120	COG0495	leucyl-tRNA aminoacylation
M0696_RS15130	COG2202	Pas domain
M0696_RS15130	COG1366	Belongs to the anti-sigma-factor antagonist family
M0696_RS15135	COG2814	Major facilitator Superfamily
M0696_RS15140	COG2433	Pfam Transposase IS66
M0696_RS15145	COG0577	efflux transmembrane transporter activity
M0696_RS15150	COG1136	(ABC) transporter
M0696_RS15155	COG2205	protein histidine kinase activity
M0696_RS15160	COG0745	RESPONSE REGULATOR receiver
M0696_RS15165	COG0577	efflux transmembrane transporter activity
M0696_RS15170	COG1136	(ABC) transporter
M0696_RS15185	COG1131	(ABC) transporter
M0696_RS15190	COG1725	Transcriptional regulator
M0696_RS15205	COG1242	4 iron, 4 sulfur cluster binding
M0696_RS15210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M0696_RS15220	COG2267	carboxylic ester hydrolase activity
M0696_RS15225	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M0696_RS15230	COG1113	amino acid transport
M0696_RS15235	COG0367	asparagine synthase
M0696_RS15240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
M0696_RS15245	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
M0696_RS15255	COG1506	peptidase
M0696_RS15260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M0696_RS15265	COG1116	anion transmembrane transporter activity
M0696_RS15270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M0696_RS15275	COG0494	nUDIX hydrolase
M0696_RS15280	COG4824	toxin secretion phage lysis holin
M0696_RS15285	COG0783	Belongs to the Dps family
M0696_RS15300	COG1854	S-ribosylhomocysteine lyase activity
M0696_RS15305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
M0696_RS15310	COG0288	reversible hydration of carbon dioxide
M0696_RS15315	COG0254	rRNA binding
M0696_RS15320	COG1271	oxidase subunit
M0696_RS15325	COG1294	oxidase, subunit
M0696_RS15335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_RS15340	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M0696_RS15340	COG1321	iron dependent repressor
M0696_RS15345	COG1121	(ABC) transporter
M0696_RS15350	COG0803	Belongs to the bacterial solute-binding protein 9 family
M0696_RS15355	COG4948	Mandelate Racemase Muconate Lactonizing
M0696_RS15360	COG0318	PFAM AMP-dependent synthetase and ligase
M0696_RS15365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M0696_RS15370	COG0596	Alpha beta hydrolase
M0696_RS15375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
M0696_RS15380	COG1169	isochorismate synthase
M0696_RS15385	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M0696_RS15390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_RS15395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_RS15400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M0696_RS15405	COG0438	transferase activity, transferring glycosyl groups
M0696_RS15415	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_RS15420	COG0438	transferase activity, transferring glycosyl groups
M0696_RS15425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_RS15430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
M0696_RS15435	COG0058	SHG alpha-glucan phosphorylase activity
M0696_RS15445	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M0696_RS15450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
M0696_RS15455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
M0696_RS15580	COG3859	Proton-coupled thiamine transporter YuaJ
M0696_RS15585	COG1247	-acetyltransferase
M0696_RS15590	COG2268	Band 7 protein
M0696_RS15595	COG1585	Membrane protein implicated in regulation of membrane protease activity
M0696_RS15600	COG2318	DinB family
M0696_RS15610	COG1454	alcohol dehydrogenase
M0696_RS15615	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS15620	COG1510	regulation of RNA biosynthetic process
M0696_RS15630	COG0569	domain protein
M0696_RS15635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M0696_RS15640	COG4682	membrane
M0696_RS15645	COG1705	Flagellar rod assembly protein muramidase FlgJ
M0696_RS15650	COG0477	Major facilitator Superfamily
M0696_RS15655	COG5553	Cysteine dioxygenase type I
M0696_RS15665	COG1968	undecaprenyl-diphosphatase activity
M0696_RS15670	COG0628	permease
M0696_RS15675	COG0673	inositol 2-dehydrogenase activity
M0696_RS15680	COG4806	L-rhamnose isomerase
M0696_RS15685	COG3254	rhamnose metabolic process
M0696_RS15690	COG1070	Carbohydrate kinase
M0696_RS15695	COG1349	DNA-binding transcription factor activity
M0696_RS15700	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS15700	COG3347	Dehydrogenase
M0696_RS15705	COG0840	transmembrane signaling receptor activity
M0696_RS15710	COG0840	transmembrane signaling receptor activity
M0696_RS15715	COG0840	transmembrane signaling receptor activity
M0696_RS15720	COG0840	transmembrane signaling receptor activity
M0696_RS15735	COG2070	2-Nitropropane dioxygenase
M0696_RS15740	COG0432	Pfam Uncharacterised protein family UPF0047
M0696_RS15745	COG0366	Alpha amylase catalytic
M0696_RS15750	COG1253	flavin adenine dinucleotide binding
M0696_RS15755	COG2738	Putative neutral zinc metallopeptidase
M0696_RS15770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M0696_RS15785	COG0166	Belongs to the GPI family
M0696_RS15790	COG1979	alcohol dehydrogenase
M0696_RS15795	COG1979	alcohol dehydrogenase
M0696_RS15800	COG2155	Conserved Protein
M0696_RS15805	COG1098	S1 RNA binding domain
M0696_RS15810	COG0436	Aminotransferase
M0696_RS15815	COG1522	sequence-specific DNA binding
M0696_RS15820	COG2267	carboxylic ester hydrolase activity
M0696_RS15830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
M0696_RS15835	COG2205	protein histidine kinase activity
M0696_RS15845	COG5018	Exonuclease
M0696_RS15855	COG2814	Major facilitator Superfamily
M0696_RS15860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_RS15865	COG3011	Protein conserved in bacteria
M0696_RS15875	COG3290	protein histidine kinase activity
M0696_RS15880	COG4565	transcriptional regulatory protein
M0696_RS15885	COG1744	ABC transporter substrate-binding protein PnrA-like
M0696_RS15890	COG3845	ABC transporter
M0696_RS15895	COG4603	Belongs to the binding-protein-dependent transport system permease family
M0696_RS15900	COG1079	Belongs to the binding-protein-dependent transport system permease family
M0696_RS15905	COG3493	citrate carrier protein
M0696_RS15915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M0696_RS15915	COG2111	Na H antiporter
M0696_RS15920	COG2111	Na H antiporter
M0696_RS15925	COG1006	Multisubunit Na H antiporter MnhC subunit
M0696_RS15930	COG0651	ATP synthesis coupled electron transport
M0696_RS15935	COG1863	multisubunit Na H antiporter MnhE subunit
M0696_RS15940	COG2212	antiporter activity
M0696_RS15945	COG1320	monovalent cation:proton antiporter activity
M0696_RS15950	COG2050	protein possibly involved in aromatic compounds catabolism
M0696_RS15955	COG2197	response regulator
M0696_RS15970	COG0142	geranyltranstransferase activity
M0696_RS15990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
M0696_RS15995	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M0696_RS16000	COG1335	isochorismatase
M0696_RS16005	COG5506	Protein of unknown function (DUF1694)
M0696_RS16020	COG0628	permease
M0696_RS16030	COG1418	mRNA catabolic process
M0696_RS16035	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16045	COG1511	domain protein
M0696_RS16050	COG0433	COG0433 Predicted ATPase
M0696_RS16050	COG1674	ftsk spoiiie
M0696_RS16055	COG4499	WXG100 protein secretion system (Wss), protein YukC
M0696_RS16060	COG5417	Belongs to the EsaB family
M0696_RS16065	COG4842	Belongs to the WXG100 family
M0696_RS16070	COG2508	Transcriptional regulator
M0696_RS16070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M0696_RS16075	COG0686	Belongs to the AlaDH PNT family
M0696_RS16080	COG5634	Uncharacterized conserved protein (DUF2278)
M0696_RS16085	COG3251	PFAM MbtH domain protein
M0696_RS16090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS16095	COG1535	isochorismatase
M0696_RS16095	COG3433	isochorismatase activity
M0696_RS16100	COG1021	2,3-dihydroxybenzoate-AMP ligase
M0696_RS16105	COG1169	isochorismate synthase
M0696_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16115	COG2819	hydrolase of the alpha beta superfamily
M0696_RS16120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M0696_RS16125	COG1268	BioY protein
M0696_RS16130	COG2056	Na+-H+ antiporter family
M0696_RS16135	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M0696_RS16140	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
M0696_RS16145	COG3584	3D domain protein
M0696_RS16160	COG1252	NADH dehydrogenase
M0696_RS16165	COG0492	ferredoxin-NADP+ reductase activity
M0696_RS16175	COG0516	GMP reductase activity
M0696_RS16180	COG0316	Belongs to the HesB IscA family
M0696_RS16185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
M0696_RS16190	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_RS16195	COG4844	belongs to the
M0696_RS16200	COG1252	NADH dehydrogenase
M0696_RS16205	COG4837	Protein of unknown function (DUF1462)
M0696_RS16210	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
M0696_RS16220	COG0083	homoserine kinase activity
M0696_RS16225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M0696_RS16230	COG0460	homoserine dehydrogenase
M0696_RS16235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M0696_RS16240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M0696_RS16245	COG0647	UMP catabolic process
M0696_RS16250	COG2445	Protein of unknown function DUF86
M0696_RS16255	COG4470	Protein conserved in bacteria
M0696_RS16265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M0696_RS16270	COG0739	heme binding
M0696_RS16280	COG3377	Domain of unknown function (DUF1805)
M0696_RS16285	COG0737	Belongs to the 5'-nucleotidase family
M0696_RS16290	COG0730	response to heat
M0696_RS16295	COG1801	Protein of unknown function DUF72
M0696_RS16305	COG1819	glycosyl
M0696_RS16310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M0696_RS16315	COG2508	Transcriptional regulator
M0696_RS16320	COG2233	PERMEase
M0696_RS16325	COG2233	PERMEase
M0696_RS16330	COG3195	allantoin biosynthetic process
M0696_RS16330	COG3648	Uricase
M0696_RS16335	COG2351	hydroxyisourate hydrolase activity
M0696_RS16350	COG2080	2 iron, 2 sulfur cluster binding
M0696_RS16355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M0696_RS16360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
M0696_RS16365	COG2068	MobA-Related Protein
M0696_RS16370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
M0696_RS16375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M0696_RS16380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M0696_RS16390	COG2356	endonuclease I
M0696_RS16395	COG3842	ATPase activity
M0696_RS16400	COG2188	Transcriptional regulator
M0696_RS16405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_RS16410	COG0395	ABC-type sugar transport system, permease component
M0696_RS16415	COG1175	transmembrane transport
M0696_RS16420	COG1653	transport
M0696_RS16425	COG2222	sugar isomerase
M0696_RS16430	COG0322	excinuclease ABC activity
M0696_RS16435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M0696_RS16450	COG0719	Fe-S assembly protein
M0696_RS16455	COG0822	iron-sulfur transferase activity
M0696_RS16460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M0696_RS16465	COG0719	Fe-S assembly protein
M0696_RS16470	COG0396	ATPase activity
M0696_RS16480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M0696_RS16485	COG1464	Belongs to the NlpA lipoprotein family
M0696_RS16490	COG2011	ABC-type metal ion transport system permease component
M0696_RS16495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M0696_RS16505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M0696_RS16510	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
M0696_RS16520	COG0509	glycine decarboxylation via glycine cleavage system
M0696_RS16525	COG1393	Belongs to the ArsC family
M0696_RS16530	COG1960	acyl-CoA dehydrogenase activity
M0696_RS16535	COG0183	Belongs to the thiolase family
M0696_RS16540	COG1024	Enoyl-CoA hydratase
M0696_RS16540	COG1250	3-hydroxyacyl-CoA dehydrogenase
M0696_RS16550	COG0506	proline dehydrogenase activity
M0696_RS16560	COG5577	PFAM Coat F domain
M0696_RS16565	COG1846	Transcriptional regulator
M0696_RS16570	COG0477	Major facilitator Superfamily
M0696_RS16575	COG1942	4-Oxalocrotonate Tautomerase
M0696_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16585	COG0583	DNA-binding transcription factor activity
M0696_RS16595	COG1120	ATPase activity
M0696_RS16610	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16615	COG0783	Belongs to the Dps family
M0696_RS16620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_RS16625	COG0745	RESPONSE REGULATOR receiver
M0696_RS16630	COG2770	Histidine kinase
M0696_RS16630	COG2205	protein histidine kinase activity
M0696_RS16640	COG1309	transcriptional regulator
M0696_RS16645	COG0114	fumarate hydratase activity
M0696_RS16655	COG0697	spore germination
M0696_RS16660	COG0814	amino acid
M0696_RS16670	COG2197	response regulator
M0696_RS16675	COG4585	Histidine kinase
M0696_RS16680	COG4758	membrane
M0696_RS16685	COG3595	metallopeptidase activity
M0696_RS16690	COG1842	Phage shock protein A
M0696_RS16695	COG4758	membrane
M0696_RS16700	COG2814	Major facilitator Superfamily
M0696_RS16705	COG2096	Adenosyltransferase
M0696_RS16710	COG1120	ATPase activity
M0696_RS16715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS16720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS16725	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16730	COG3386	PFAM SMP-30 Gluconolaconase
M0696_RS16735	COG2205	protein histidine kinase activity
M0696_RS16740	COG0745	RESPONSE REGULATOR receiver
M0696_RS16750	COG1191	sigma factor activity
M0696_RS16760	COG2140	Oxalate decarboxylase
M0696_RS16770	COG0577	efflux transmembrane transporter activity
M0696_RS16775	COG1136	(ABC) transporter
M0696_RS16780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M0696_RS16785	COG1120	ATPase activity
M0696_RS16790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS16795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M0696_RS16800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS16805	COG0531	amino acid
M0696_RS16815	COG1988	membrane-bound metal-dependent
M0696_RS16820	COG1368	sulfuric ester hydrolase activity
M0696_RS16825	COG1910	domain protein
M0696_RS16830	COG0725	ABC transporter, periplasmic molybdate-binding protein
M0696_RS16835	COG4149	molybdate abc transporter
M0696_RS16840	COG0656	L-ascorbic acid biosynthetic process
M0696_RS16850	COG0025	NhaP-type Na H and K H
M0696_RS16855	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M0696_RS16860	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M0696_RS16865	COG3973	AAA domain
M0696_RS16870	COG2860	membrane
M0696_RS16875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M0696_RS16880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M0696_RS16885	COG2217	Heavy metal translocating P-type atpase
M0696_RS16890	COG2217	Heavy metal translocating P-type atpase
M0696_RS16895	COG2608	mercury ion transmembrane transporter activity
M0696_RS16900	COG1937	Protein conserved in bacteria
M0696_RS16905	COG0673	inositol 2-dehydrogenase activity
M0696_RS16910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M0696_RS16915	COG1289	transmembrane transporter activity
M0696_RS16920	COG1802	Transcriptional regulator
M0696_RS16925	COG0697	spore germination
M0696_RS16935	COG2076	Multidrug Resistance protein
M0696_RS16940	COG1309	transcriptional regulator
M0696_RS16945	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS16955	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
M0696_RS16960	COG0557	exoribonuclease II activity
M0696_RS16965	COG1647	Serine aminopeptidase, S33
M0696_RS16970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M0696_RS16975	COG0596	Alpha beta hydrolase
M0696_RS16980	COG1476	TRANSCRIPTIONal
M0696_RS16985	COG1396	sequence-specific DNA binding
M0696_RS16990	COG1396	sequence-specific DNA binding
M0696_RS16995	COG1733	regulation of RNA biosynthetic process
M0696_RS17000	COG0840	transmembrane signaling receptor activity
M0696_RS17005	COG1174	glycine betaine transport
M0696_RS17010	COG1732	Glycine betaine
M0696_RS17015	COG1174	glycine betaine transport
M0696_RS17020	COG0517	IMP dehydrogenase activity
M0696_RS17020	COG1125	glycine betaine transport
M0696_RS17025	COG1510	regulation of RNA biosynthetic process
M0696_RS17030	COG1174	glycine betaine transport
M0696_RS17035	COG1732	Glycine betaine
M0696_RS17040	COG1174	glycine betaine transport
M0696_RS17045	COG1125	glycine betaine transport
M0696_RS17045	COG0517	IMP dehydrogenase activity
M0696_RS17050	COG1510	regulation of RNA biosynthetic process
M0696_RS17060	COG3064	Membrane
M0696_RS17065	COG4640	response to antibiotic
M0696_RS17070	COG0456	acetyltransferase
M0696_RS17080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M0696_RS17085	COG0149	triose-phosphate isomerase activity
M0696_RS17090	COG0126	phosphoglycerate kinase activity
M0696_RS17095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M0696_RS17100	COG2390	Transcriptional regulator
M0696_RS17105	COG2814	Major facilitator Superfamily
M0696_RS17110	COG1609	Transcriptional regulator
M0696_RS17115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_RS17120	COG0583	DNA-binding transcription factor activity
M0696_RS17125	COG0697	spore germination
M0696_RS17130	COG1113	amino acid transport
M0696_RS17135	COG3858	chitin binding
M0696_RS17140	COG1556	Lactate utilization protein
M0696_RS17145	COG1139	Iron-sulfur cluster binding protein
M0696_RS17150	COG0247	lactate metabolic process
M0696_RS17165	COG2197	response regulator
M0696_RS17170	COG4585	Histidine kinase
M0696_RS17175	COG0842	Transport permease protein
M0696_RS17180	COG1131	(ABC) transporter
M0696_RS17185	COG0596	Alpha beta hydrolase
M0696_RS17190	COG2208	phosphoserine phosphatase activity
M0696_RS17195	COG3867	Arabinogalactan endo-beta-1,4-galactanase
M0696_RS17200	COG1874	Beta-galactosidase
M0696_RS17205	COG3833	ABC-type maltose transport systems, permease component
M0696_RS17210	COG1175	transmembrane transport
M0696_RS17215	COG2182	Extracellular solute-binding protein
M0696_RS17220	COG1609	Transcriptional regulator
M0696_RS17225	COG2186	Transcriptional regulator
M0696_RS17230	COG1620	l-lactate permease
M0696_RS17235	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M0696_RS17245	COG5039	Polysaccharide pyruvyl transferase
M0696_RS17250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M0696_RS17255	COG0110	maltose O-acetyltransferase activity
M0696_RS17260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M0696_RS17265	COG2244	polysaccharide biosynthetic process
M0696_RS17270	COG1216	Glycosyl transferase, family 2
M0696_RS17275	COG5039	Polysaccharide pyruvyl transferase
M0696_RS17280	COG1216	Glycosyl transferase, family 2
M0696_RS17290	COG0438	transferase activity, transferring glycosyl groups
M0696_RS17295	COG1215	transferase activity, transferring glycosyl groups
M0696_RS17300	COG0438	transferase activity, transferring glycosyl groups
M0696_RS17305	COG1086	Polysaccharide biosynthesis protein
M0696_RS17310	COG0489	protein tyrosine kinase activity
M0696_RS17315	COG3944	biosynthesis protein
M0696_RS17320	COG1396	sequence-specific DNA binding
M0696_RS17325	COG2272	Belongs to the type-B carboxylesterase lipase family
M0696_RS17335	COG3479	Phenolic acid decarboxylase
M0696_RS17345	COG1794	racemase activity, acting on amino acids and derivatives
M0696_RS17350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M0696_RS17355	COG0473	3-isopropylmalate dehydrogenase activity
M0696_RS17360	COG1621	beta-fructofuranosidase activity
M0696_RS17365	COG1621	beta-fructofuranosidase activity
M0696_RS17370	COG0577	efflux transmembrane transporter activity
M0696_RS17375	COG1136	(ABC) transporter
M0696_RS17375	COG0577	efflux transmembrane transporter activity
M0696_RS17415	COG1132	(ABC) transporter
M0696_RS17445	COG3290	protein histidine kinase activity
M0696_RS17450	COG3279	Response regulator of the LytR AlgR family
M0696_RS17455	COG0531	amino acid
M0696_RS17460	COG1309	transcriptional regulator
M0696_RS17465	COG2076	Multidrug Resistance protein
M0696_RS17470	COG2076	Multidrug Resistance protein
M0696_RS17490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M0696_RS17495	COG0366	Alpha amylase catalytic
M0696_RS17500	COG1554	hydrolase, family 65, central catalytic
M0696_RS17505	COG5521	maltodextrose utilization protein MalA
M0696_RS17510	COG3833	ABC-type maltose transport systems, permease component
M0696_RS17515	COG1175	transmembrane transport
M0696_RS17520	COG2182	Extracellular solute-binding protein
M0696_RS17525	COG0366	Alpha amylase catalytic
M0696_RS17530	COG1609	Transcriptional regulator
M0696_RS17535	COG1611	Belongs to the LOG family
M0696_RS17540	COG1694	Mazg nucleotide pyrophosphohydrolase
M0696_RS17545	COG0659	secondary active sulfate transmembrane transporter activity
M0696_RS17550	COG0288	reversible hydration of carbon dioxide
M0696_RS17555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M0696_RS17560	COG0577	efflux transmembrane transporter activity
M0696_RS17565	COG1136	(ABC) transporter
M0696_RS17570	COG5002	protein histidine kinase activity
M0696_RS17575	COG0745	RESPONSE REGULATOR receiver
M0696_RS17585	COG2162	N-hydroxyarylamine O-acetyltransferase activity
M0696_RS17590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS17595	COG1481	regulation of sporulation
M0696_RS17600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
M0696_RS17605	COG1660	Displays ATPase and GTPase activities
M0696_RS17610	COG1051	belongs to the nudix hydrolase family
M0696_RS17615	COG0492	ferredoxin-NADP+ reductase activity
M0696_RS17620	COG3883	PFAM NLP P60 protein
M0696_RS17620	COG0791	NLP P60 protein
M0696_RS17625	COG0457	Tetratricopeptide repeat
M0696_RS17630	COG1132	(ABC) transporter
M0696_RS17650	COG0140	phosphoribosyl-ATP diphosphatase activity
M0696_RS17650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M0696_RS17655	COG0107	imidazoleglycerol-phosphate synthase activity
M0696_RS17660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
M0696_RS17665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M0696_RS17670	COG0131	Imidazoleglycerol-phosphate dehydratase
M0696_RS17675	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M0696_RS17680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M0696_RS17685	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
M0696_RS17690	COG4990	cell redox homeostasis
M0696_RS17695	COG5297	Belongs to the glycosyl hydrolase family 6
M0696_RS17700	COG0110	maltose O-acetyltransferase activity
M0696_RS17705	COG0546	phosphoglycolate phosphatase activity
M0696_RS17710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
M0696_RS17715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M0696_RS17720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
M0696_RS17725	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
M0696_RS17730	COG0363	glucosamine-6-phosphate deaminase activity
M0696_RS17735	COG2188	Transcriptional regulator
M0696_RS17740	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M0696_RS17745	COG1846	Transcriptional regulator
M0696_RS17750	COG2124	cytochrome p450
M0696_RS17760	COG1846	Transcriptional regulator
M0696_RS17765	COG2814	Major facilitator Superfamily
M0696_RS17770	COG1950	PFAM Membrane protein of
M0696_RS17775	COG1983	PspC domain protein
M0696_RS17780	COG3595	metallopeptidase activity
M0696_RS17795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M0696_RS17800	COG0556	nucleotide-excision repair
M0696_RS17805	COG4897	Protein conserved in bacteria
M0696_RS17810	COG0574	Belongs to the PEP-utilizing enzyme family
M0696_RS17810	COG3848	Pyruvate phosphate dikinase
M0696_RS17815	COG1309	transcriptional regulator
M0696_RS17820	COG2814	Major facilitator Superfamily
M0696_RS17825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_RS17835	COG0793	Belongs to the peptidase S41A family
M0696_RS17835	COG3409	Peptidoglycan-binding domain 1 protein
M0696_RS17840	COG2177	Part of the ABC transporter FtsEX involved in
M0696_RS17845	COG2884	Cell division ATP-binding protein ftsE
M0696_RS17850	COG2010	Cytochrome c
M0696_RS17855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS17865	COG0653	protein targeting
M0696_RS17870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M0696_RS17885	COG1516	flagellar protein fliS
M0696_RS17890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M0696_RS17895	COG1334	flagellar protein FlaG
M0696_RS17900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M0696_RS17905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
M0696_RS17910	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
M0696_RS17920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M0696_RS17925	COG4786	Flagellar basal body rod
M0696_RS17925	COG1256	bacterial-type flagellum assembly
M0696_RS17930	COG3418	PFAM FlgN family protein
M0696_RS17935	COG2747	anti-sigma28 factor FlgM
M0696_RS17945	COG1040	competence protein
M0696_RS17955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M0696_RS17960	COG1307	EDD domain protein, DegV family
M0696_RS17965	COG2197	response regulator
M0696_RS17970	COG4585	Histidine kinase
M0696_RS17975	COG1739	Uncharacterized protein family UPF0029
M0696_RS17980	COG1316	TRANSCRIPTIONal
M0696_RS17985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M0696_RS17990	COG0438	transferase activity, transferring glycosyl groups
M0696_RS17995	COG1215	transferase activity, transferring glycosyl groups
M0696_RS18000	COG3206	protein involved in exopolysaccharide biosynthesis
M0696_RS18005	COG3307	-O-antigen
M0696_RS18010	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_RS18015	COG0438	transferase activity, transferring glycosyl groups
M0696_RS18015	COG0297	glycogen (starch) synthase activity
M0696_RS18020	COG2244	polysaccharide biosynthetic process
M0696_RS18035	COG0860	N-Acetylmuramoyl-L-alanine amidase
M0696_RS18035	COG2247	cell wall binding repeat
M0696_RS18040	COG2247	cell wall binding repeat
M0696_RS18040	COG2385	sporulation resulting in formation of a cellular spore
M0696_RS18050	COG1316	TRANSCRIPTIONal
M0696_RS18055	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M0696_RS18075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M0696_RS18080	COG1134	teichoic acid transport
M0696_RS18085	COG1682	transport, permease protein
M0696_RS18100	COG1215	transferase activity, transferring glycosyl groups
M0696_RS18100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M0696_RS18105	COG0463	Glycosyl transferase, family 2
M0696_RS18150	COG4193	domain, Protein
M0696_RS18155	COG1482	cell wall glycoprotein biosynthetic process
M0696_RS18160	COG0697	spore germination
M0696_RS18165	COG0814	amino acid
M0696_RS18175	COG2814	Major facilitator Superfamily
M0696_RS18180	COG1316	TRANSCRIPTIONal
M0696_RS18185	COG0561	phosphatase activity
M0696_RS18190	COG0791	NLP P60 protein
M0696_RS18200	COG2843	Capsule synthesis protein
M0696_RS18210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M0696_RS18215	COG1609	Transcriptional regulator
M0696_RS18220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_RS18225	COG1869	D-ribose catabolic process
M0696_RS18230	COG1129	ABC transporter
M0696_RS18235	COG1172	Belongs to the binding-protein-dependent transport system permease family
M0696_RS18240	COG1879	ABC-type sugar transport system periplasmic component
M0696_RS18245	COG3103	Sh3 type 3 domain protein
M0696_RS18255	COG2249	NAD(P)H dehydrogenase (quinone) activity
M0696_RS18260	COG3527	Alpha-acetolactate decarboxylase
M0696_RS18265	COG0028	Belongs to the TPP enzyme family
M0696_RS18270	COG0583	DNA-binding transcription factor activity
M0696_RS18275	COG5337	Spore coat protein CotH
M0696_RS18285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M0696_RS18295	COG0405	Gamma-glutamyltransferase
M0696_RS18300	COG1522	sequence-specific DNA binding
M0696_RS18305	COG2059	Chromate
M0696_RS18310	COG2059	Chromate
M0696_RS18320	COG0655	NAD(P)H dehydrogenase (quinone) activity
M0696_RS18325	COG0583	DNA-binding transcription factor activity
M0696_RS18335	COG2207	Transcriptional regulator
M0696_RS18335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS18360	COG5444	nuclease activity
M0696_RS18375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
M0696_RS18380	COG4464	protein tyrosine phosphatase activity
M0696_RS18385	COG0489	protein tyrosine kinase activity
M0696_RS18390	COG3944	biosynthesis protein
M0696_RS18400	COG4715	Zinc finger, swim domain protein
M0696_RS18405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M0696_RS18410	COG0561	phosphatase activity
M0696_RS18415	COG1349	DNA-binding transcription factor activity
M0696_RS18420	COG0629	single-stranded DNA binding
M0696_RS18435	COG3764	Sortase (surface protein transpeptidase)
M0696_RS18445	COG3279	Response regulator of the LytR AlgR family
M0696_RS18455	COG0745	RESPONSE REGULATOR receiver
M0696_RS18455	COG2972	Histidine kinase
M0696_RS18460	COG1970	mechanosensitive ion channel activity
M0696_RS18465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M0696_RS18470	COG0457	Tetratricopeptide repeat
M0696_RS18475	COG4786	Flagellar basal body rod
M0696_RS18480	COG4786	Flagellar basal body rod
M0696_RS18485	COG1077	Cell shape determining protein MreB Mrl
M0696_RS18490	COG1609	Transcriptional regulator
M0696_RS18500	COG1846	Transcriptional regulator
M0696_RS18505	COG2814	Major facilitator Superfamily
M0696_RS18510	COG3420	alginic acid biosynthetic process
M0696_RS18515	COG1953	Uracil, thiamine, allantoin
M0696_RS18520	COG0477	Major facilitator Superfamily
M0696_RS18535	COG0004	ammonium transporteR
M0696_RS18540	COG0347	Belongs to the P(II) protein family
M0696_RS18545	COG0671	phosphoesterase, PA-phosphatase related
M0696_RS18555	COG0739	heme binding
M0696_RS18560	COG1247	-acetyltransferase
M0696_RS18570	COG2089	acid synthase
M0696_RS18580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_RS18585	COG0789	Transcriptional regulator
M0696_RS18595	COG2910	NAD(P)H-binding
M0696_RS18600	COG1959	2 iron, 2 sulfur cluster binding
M0696_RS18605	COG0804	urea catabolic process
M0696_RS18610	COG0832	Belongs to the urease beta subunit family
M0696_RS18615	COG0831	urea catabolic process
M0696_RS18645	COG3237	CsbD-like
M0696_RS18650	COG1994	Peptidase M50
M0696_RS18655	COG0457	Tetratricopeptide repeat
M0696_RS18660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M0696_RS18665	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M0696_RS18675	COG2304	oxidoreductase activity
M0696_RS18680	COG2304	oxidoreductase activity
M0696_RS18685	COG2385	sporulation resulting in formation of a cellular spore
M0696_RS18690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M0696_RS18700	COG4836	Membrane
M0696_RS18715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
M0696_RS18720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
M0696_RS18725	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
M0696_RS18730	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M0696_RS18735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M0696_RS18745	COG0356	it plays a direct role in the translocation of protons across the membrane
M0696_RS18755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
M0696_RS18760	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
M0696_RS18765	COG4475	Protein of unknown function (DUF436)
M0696_RS18770	COG0698	ribose 5-phosphate isomerase
M0696_RS18775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M0696_RS18780	COG1971	Probably functions as a manganese efflux pump
M0696_RS18785	COG0009	L-threonylcarbamoyladenylate synthase
M0696_RS18790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M0696_RS18810	COG2890	protein-(glutamine-N5) methyltransferase activity
M0696_RS18815	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M0696_RS18820	COG0346	lactoylglutathione lyase activity
M0696_RS18825	COG0789	Transcriptional regulator
M0696_RS18830	COG0679	Auxin Efflux Carrier
M0696_RS18835	COG0281	malic enzyme
M0696_RS18840	COG1435	thymidine kinase activity
M0696_RS18850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M0696_RS18860	COG1494	fructose-1,6-bisphosphatase
M0696_RS18865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M0696_RS18870	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M0696_RS18875	COG0191	fructose-bisphosphate aldolase activity
M0696_RS18880	COG2204	response regulator
M0696_RS18885	COG4821	SIS domain
M0696_RS18890	COG0504	CTP synthase activity
M0696_RS18895	COG3343	RNA polymerase activity
M0696_RS18900	COG1960	acyl-CoA dehydrogenase activity
M0696_RS18905	COG2181	nitrate reductase activity
M0696_RS18905	COG0247	lactate metabolic process
M0696_RS18910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_RS18915	COG4294	response to UV
M0696_RS18925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M0696_RS18930	COG1132	(ABC) transporter
M0696_RS18935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M0696_RS18945	COG2181	nitrate reductase activity
M0696_RS18950	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
M0696_RS18955	COG1140	nitrate reductase beta subunit
M0696_RS18960	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
M0696_RS18965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M0696_RS18975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M0696_RS18980	COG2223	nitrite transmembrane transporter activity
M0696_RS18985	COG0018	arginyl-trna synthetase
M0696_RS18990	COG4506	Protein conserved in bacteria
M0696_RS19000	COG0535	radical SAM domain protein
M0696_RS19010	COG1131	(ABC) transporter
M0696_RS19035	COG3391	amine dehydrogenase activity
M0696_RS19040	COG3391	amine dehydrogenase activity
M0696_RS19045	COG0457	Tetratricopeptide repeat
M0696_RS19060	COG0010	Belongs to the arginase family
M0696_RS19065	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
M0696_RS19070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M0696_RS19080	COG1994	Peptidase M50
M0696_RS19085	COG1942	4-Oxalocrotonate Tautomerase
M0696_RS19090	COG1846	Transcriptional regulator
M0696_RS19095	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M0696_RS19105	COG3465	dGTPase activity
M0696_RS19110	COG1078	dGTPase activity
M0696_RS19115	COG4844	belongs to the
M0696_RS19125	COG0697	spore germination
M0696_RS19130	COG0095	Lipoate-protein ligase
M0696_RS19135	COG0583	DNA-binding transcription factor activity
M0696_RS19140	COG0280	phosphate acetyltransferase
M0696_RS19145	COG3253	May function as heme-dependent peroxidase
M0696_RS19150	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS19155	COG0436	Aminotransferase
M0696_RS19160	COG2814	Major facilitator Superfamily
M0696_RS19165	COG0151	Belongs to the GarS family
M0696_RS19170	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS19175	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS19180	COG0077	Prephenate dehydratase
M0696_RS19185	COG2814	Major facilitator Superfamily
M0696_RS19190	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS19195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M0696_RS19205	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
M0696_RS19210	COG1091	dTDP-4-dehydrorhamnose reductase activity
M0696_RS19215	COG1088	dTDP-glucose 4,6-dehydratase activity
M0696_RS19220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M0696_RS19225	COG3980	spore coat polysaccharide biosynthesis protein
M0696_RS19230	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
M0696_RS19235	COG2089	acid synthase
M0696_RS19240	COG0456	acetyltransferase
M0696_RS19245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M0696_RS19250	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
M0696_RS19255	COG0463	Glycosyl transferase, family 2
M0696_RS19265	COG2363	Small membrane protein
M0696_RS19270	COG2233	PERMEase
M0696_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS19285	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
M0696_RS19290	COG1216	Glycosyl transferase, family 2
M0696_RS19300	COG0351	phosphomethylpyrimidine kinase
M0696_RS19310	COG1621	beta-fructofuranosidase activity
M0696_RS19315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS19315	COG1263	PTS System
M0696_RS19320	COG2116	formate transmembrane transporter activity
M0696_RS19325	COG3711	transcriptional antiterminator
M0696_RS19335	COG1404	Belongs to the peptidase S8 family
M0696_RS19340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_RS19345	COG0778	Nitroreductase
M0696_RS19350	COG0772	Belongs to the SEDS family
M0696_RS19360	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M0696_RS19365	COG1845	cytochrome c oxidase, subunit III
M0696_RS19380	COG2261	transglycosylase associated protein
M0696_RS19385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M0696_RS19390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
M0696_RS19395	COG2246	polysaccharide biosynthetic process
M0696_RS19400	COG1309	transcriptional regulator
M0696_RS19410	COG3162	membrane
M0696_RS19415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M0696_RS19420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M0696_RS19425	COG2837	iron assimilation
M0696_RS19430	COG2822	iron ion transport
M0696_RS19435	COG0672	)-iron permease
M0696_RS19440	COG0352	thiamine-phosphate diphosphorylase activity
M0696_RS19445	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
M0696_RS19450	COG0583	DNA-binding transcription factor activity
M0696_RS19455	COG1380	Effector of murein hydrolase LrgA
M0696_RS19460	COG1346	cytolysis
M0696_RS19465	COG2814	Major facilitator Superfamily
M0696_RS19470	COG4895	conserved protein (DUF2196)
M0696_RS19475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M0696_RS19480	COG0346	lactoylglutathione lyase activity
M0696_RS19490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_RS19495	COG1404	Belongs to the peptidase S8 family
M0696_RS19500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS19500	COG1263	PTS System
M0696_RS19505	COG3711	transcriptional antiterminator
M0696_RS19510	COG1442	glycosyl transferase family 8
M0696_RS19515	COG5522	Integral membrane protein (intg_mem_TP0381)
M0696_RS19520	COG1846	Transcriptional regulator
M0696_RS19525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M0696_RS19530	COG2234	aminopeptidase activity
M0696_RS19535	COG2357	RelA SpoT domain protein
M0696_RS19540	COG1575	Belongs to the MenA family. Type 1 subfamily
M0696_RS19555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M0696_RS19560	COG1696	Membrane protein involved in D-alanine export
M0696_RS19565	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M0696_RS19570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M0696_RS19575	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
M0696_RS19580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M0696_RS19615	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M0696_RS19620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M0696_RS19645	COG1486	melibiose metabolic process
M0696_RS19650	COG1447	Phosphotransferase system cellobiose-specific component IIA
M0696_RS19655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_RS19660	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M0696_RS19665	COG3711	transcriptional antiterminator
M0696_RS19665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M0696_RS19675	COG2094	Belongs to the DNA glycosylase MPG family
M0696_RS19680	COG0753	catalase activity
M0696_RS19685	COG2814	Major facilitator Superfamily
M0696_RS19690	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
M0696_RS19695	COG1131	(ABC) transporter
M0696_RS19715	COG1595	DNA-templated transcription, initiation
M0696_RS19720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M0696_RS19725	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M0696_RS19730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
M0696_RS19735	COG4988	ABC transporter
M0696_RS19740	COG1294	oxidase, subunit
M0696_RS19745	COG1271	oxidase subunit
M0696_RS19750	COG3493	citrate carrier protein
M0696_RS19755	COG0501	Belongs to the peptidase M48B family
M0696_RS19765	COG0726	polysaccharide deacetylase
M0696_RS19780	COG3842	ATPase activity
M0696_RS19785	COG2508	Transcriptional regulator
M0696_RS19790	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS19795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M0696_RS19805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M0696_RS19815	COG4585	Histidine kinase
M0696_RS19820	COG2197	response regulator
M0696_RS19825	COG2195	Cleaves the N-terminal amino acid of tripeptides
M0696_RS19835	COG4894	glucomannan catabolic process
M0696_RS19840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_RS19845	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
M0696_RS19850	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS19855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M0696_RS19860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M0696_RS19865	COG2610	gluconate transmembrane transporter activity
M0696_RS19870	COG0500	methyltransferase
M0696_RS19875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_RS19890	COG0753	catalase activity
M0696_RS19890	COG0693	protein deglycase activity
M0696_RS19895	COG2851	Citrate transporter
M0696_RS19900	COG2323	membrane
M0696_RS19910	COG2723	6-phospho-beta-galactosidase activity
M0696_RS19915	COG2190	(PTS) system
M0696_RS19915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS19915	COG1263	PTS System
M0696_RS19920	COG3711	transcriptional antiterminator
M0696_RS19930	COG2270	Major facilitator Superfamily
M0696_RS19935	COG0513	Belongs to the DEAD box helicase family
M0696_RS19940	COG3401	FG-GAP repeat protein
M0696_RS19940	COG2755	lipolytic protein G-D-S-L family
M0696_RS20000	COG0697	spore germination
M0696_RS20010	COG0861	Integral membrane protein TerC family
M0696_RS20015	COG0589	response to stress
M0696_RS20020	COG2723	6-phospho-beta-galactosidase activity
M0696_RS20025	COG2190	(PTS) system
M0696_RS20025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS20025	COG1263	PTS System
M0696_RS20035	COG5444	nuclease activity
M0696_RS20050	COG3507	Belongs to the glycosyl hydrolase 43 family
M0696_RS20065	COG2986	histidine ammonia-lyase
M0696_RS20070	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M0696_RS20075	COG1228	amidohydrolase
M0696_RS20080	COG0010	Belongs to the arginase family
M0696_RS20085	COG0833	amino acid
M0696_RS20090	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
M0696_RS20095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M0696_RS20100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
M0696_RS20105	COG2390	Transcriptional regulator
M0696_RS20115	COG3192	ethanolamine utilization protein
M0696_RS20120	COG2079	MmgE PrpD family protein
M0696_RS20125	COG1473	amidohydrolase
M0696_RS20130	COG1126	abc transporter atp-binding protein
M0696_RS20135	COG0765	amino acid transport
M0696_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M0696_RS20145	COG0456	acetyltransferase
M0696_RS20150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M0696_RS20155	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
M0696_RS20160	COG0561	phosphatase activity
M0696_RS20185	COG5294	Protein conserved in bacteria
M0696_RS20190	COG0577	efflux transmembrane transporter activity
M0696_RS20195	COG1136	(ABC) transporter
M0696_RS20200	COG2205	protein histidine kinase activity
M0696_RS20205	COG0745	RESPONSE REGULATOR receiver
M0696_RS20215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M0696_RS20220	COG0191	fructose-bisphosphate aldolase activity
M0696_RS20225	COG1082	Xylose isomerase domain protein TIM barrel
M0696_RS20230	COG1082	Xylose isomerase domain protein TIM barrel
M0696_RS20235	COG0673	inositol 2-dehydrogenase activity
M0696_RS20240	COG2814	Major facilitator Superfamily
M0696_RS20245	COG1082	Xylose isomerase domain protein TIM barrel
M0696_RS20250	COG3962	Belongs to the TPP enzyme family
M0696_RS20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M0696_RS20265	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS20270	COG1349	DNA-binding transcription factor activity
M0696_RS20275	COG0667	Aldo Keto reductase
M0696_RS20290	COG2814	Major facilitator Superfamily
M0696_RS20295	COG0326	Molecular chaperone. Has ATPase activity
M0696_RS20305	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS20310	COG1309	transcriptional regulator
M0696_RS20315	COG1012	belongs to the aldehyde dehydrogenase family
M0696_RS20325	COG0667	Aldo Keto reductase
M0696_RS20330	COG0789	Transcriptional regulator
M0696_RS20335	COG1714	RDD family
M0696_RS20340	COG2311	Membrane
M0696_RS20345	COG1917	Cupin 2, conserved barrel domain protein
M0696_RS20350	COG1309	transcriptional regulator
M0696_RS20355	COG1028	Short-chain dehydrogenase reductase Sdr
M0696_RS20380	COG5039	Polysaccharide pyruvyl transferase
M0696_RS20385	COG1929	Belongs to the glycerate kinase type-1 family
M0696_RS20390	COG1802	Transcriptional regulator
M0696_RS20395	COG1070	Carbohydrate kinase
M0696_RS20400	COG2610	gluconate transmembrane transporter activity
M0696_RS20405	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
M0696_RS20410	COG0450	alkyl hydroperoxide reductase
M0696_RS20415	COG3634	alkyl hydroperoxide reductase activity
M0696_RS20425	COG2723	6-phospho-beta-galactosidase activity
M0696_RS20430	COG2190	(PTS) system
M0696_RS20430	COG1263	PTS System
M0696_RS20430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M0696_RS20435	COG2188	Transcriptional regulator
M0696_RS20445	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
M0696_RS20450	COG1192	Involved in chromosome partitioning
M0696_RS20470	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
M0696_RS20485	COG1063	alcohol dehydrogenase
M0696_RS20505	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
M0696_RS20510	COG0456	acetyltransferase
M0696_RS20515	COG0457	Tetratricopeptide repeat
M0696_RS20525	COG0010	Belongs to the arginase family
M0696_RS20530	COG0833	amino acid
M0696_RS20535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M0696_RS20540	COG3829	transcription factor binding
M0696_RS20545	COG5002	protein histidine kinase activity
M0696_RS20550	COG0745	RESPONSE REGULATOR receiver
M0696_RS20570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M0696_RS20575	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M0696_RS20580	COG4853	Protein conserved in bacteria
M0696_RS20585	COG4863	YycH protein
M0696_RS20590	COG5002	protein histidine kinase activity
M0696_RS20595	COG0745	RESPONSE REGULATOR receiver
M0696_RS20625	COG0346	lactoylglutathione lyase activity
M0696_RS20630	COG0305	Participates in initiation and elongation during chromosome replication
M0696_RS20645	COG3093	addiction module antidote protein HigA
M0696_RS20650	COG2807	transmembrane transport
M0696_RS20655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
M0696_RS20660	COG0359	binds to the 23S rRNA
M0696_RS20665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
M0696_RS20670	COG4241	membrane
M0696_RS20680	COG5577	PFAM Coat F domain
M0696_RS20685	COG1733	regulation of RNA biosynthetic process
M0696_RS20690	COG1227	inorganic diphosphatase activity
M0696_RS20700	COG2271	Major facilitator Superfamily
M0696_RS20705	COG4978	Transcriptional regulator
M0696_RS20705	COG0789	Transcriptional regulator
M0696_RS20725	COG2814	Major facilitator Superfamily
M0696_RS20730	COG0583	DNA-binding transcription factor activity
M0696_RS20735	COG2153	protein acetylation
M0696_RS20745	COG0583	DNA-binding transcription factor activity
M0696_RS20765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M0696_RS20770	COG1733	regulation of RNA biosynthetic process
M0696_RS20790	COG2315	Protein conserved in bacteria
M0696_RS20820	COG1131	(ABC) transporter
M0696_RS20850	COG1733	regulation of RNA biosynthetic process
M0696_RS20855	COG0657	acetylesterase activity
M0696_RS20860	COG1309	transcriptional regulator
M0696_RS20865	COG1902	pentaerythritol trinitrate reductase activity
M0696_RS20870	COG1331	Highly conserved protein containing a thioredoxin domain
M0696_RS20875	COG1266	CAAX protease self-immunity
M0696_RS20880	COG2814	Major facilitator Superfamily
M0696_RS20880	COG0477	Major facilitator Superfamily
M0696_RS20885	COG0110	maltose O-acetyltransferase activity
M0696_RS20890	COG0346	lactoylglutathione lyase activity
M0696_RS20895	COG1609	Transcriptional regulator
M0696_RS20900	COG0708	Exodeoxyribonuclease III
M0696_RS20905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M0696_RS20910	COG0629	single-stranded DNA binding
M0696_RS20915	COG0360	Binds together with S18 to 16S ribosomal RNA
M0696_RS20920	COG0012	GTP binding
M0696_RS20925	COG0243	molybdopterin cofactor binding
M0696_RS20930	COG4481	Protein conserved in bacteria
M0696_RS20935	COG3949	Membrane
M0696_RS20945	COG1475	DNA binding
M0696_RS20950	COG1192	Involved in chromosome partitioning
M0696_RS20960	COG1475	DNA binding
M0696_RS20965	COG0357	Ribosomal RNA small subunit methyltransferase G
M0696_RS20970	COG0445	tRNA wobble uridine modification
M0696_RS20975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
M0696_RS20980	COG1847	R3H domain protein
M0696_RS20985	COG0706	membrane insertase activity
M0696_RS20990	COG0594	ribonuclease P activity