locus-tag	class	description
JNE45_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JNE45_RS00010	COG0592	DNA-directed DNA polymerase activity
JNE45_RS00015	COG2501	S4 domain
JNE45_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JNE45_RS00030	COG0187	DNA topoisomerase II activity
JNE45_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNE45_RS00070	COG0517	IMP dehydrogenase activity
JNE45_RS00070	COG0516	GMP reductase activity
JNE45_RS00075	COG1686	Belongs to the peptidase S11 family
JNE45_RS00080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JNE45_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JNE45_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JNE45_RS00100	COG0840	transmembrane signaling receptor activity
JNE45_RS00110	COG1428	Deoxynucleoside kinase
JNE45_RS00115	COG1428	Deoxynucleoside kinase
JNE45_RS00120	COG3858	chitin binding
JNE45_RS00120	COG1388	LysM domain
JNE45_RS00125	COG1335	isochorismatase
JNE45_RS00130	COG0590	tRNA wobble adenosine to inosine editing
JNE45_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JNE45_RS00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JNE45_RS00150	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JNE45_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JNE45_RS00200	COG3853	Toxic anion resistance protein (TelA)
JNE45_RS00205	COG1982	Orn Lys Arg decarboxylase major
JNE45_RS00210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JNE45_RS00215	COG3870	Protein conserved in bacteria
JNE45_RS00220	COG1728	Protein conserved in bacteria
JNE45_RS00225	COG0470	DNA polymerase III
JNE45_RS00230	COG1774	PSP1 C-terminal conserved region
JNE45_RS00235	COG4467	Involved in initiation control of chromosome replication
JNE45_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JNE45_RS00245	COG2827	Endonuclease containing a URI domain
JNE45_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JNE45_RS00255	COG2002	toxin-antitoxin pair type II binding
JNE45_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE45_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE45_RS00265	COG0084	hydrolase, TatD family'
JNE45_RS00270	COG3584	3D domain protein
JNE45_RS00270	COG3583	domain protein
JNE45_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JNE45_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JNE45_RS00290	COG4466	Protein conserved in bacteria
JNE45_RS00300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JNE45_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE45_RS00310	COG0251	oxidation-reduction process
JNE45_RS00315	COG2088	sporulation resulting in formation of a cellular spore
JNE45_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JNE45_RS00330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JNE45_RS00335	COG0193	aminoacyl-tRNA hydrolase activity
JNE45_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JNE45_RS00350	COG2002	toxin-antitoxin pair type II binding
JNE45_RS00355	COG2244	polysaccharide biosynthetic process
JNE45_RS00360	COG3956	TIGRFAM MazG family protein
JNE45_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JNE45_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JNE45_RS00385	COG1098	S1 RNA binding domain
JNE45_RS00400	COG2208	phosphoserine phosphatase activity
JNE45_RS00405	COG2304	oxidoreductase activity
JNE45_RS00410	COG0515	serine threonine protein kinase
JNE45_RS00415	COG0037	tRNA processing
JNE45_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JNE45_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JNE45_RS00430	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JNE45_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JNE45_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JNE45_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE45_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JNE45_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
JNE45_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE45_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JNE45_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JNE45_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JNE45_RS00480	COG1396	sequence-specific DNA binding
JNE45_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JNE45_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JNE45_RS00570	COG4463	regulation of RNA biosynthetic process
JNE45_RS00575	COG3880	PFAM UvrB UvrC protein
JNE45_RS00580	COG3869	Catalyzes the specific phosphorylation of arginine residues in
JNE45_RS00585	COG0542	response to heat
JNE45_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JNE45_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JNE45_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
JNE45_RS00605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JNE45_RS00610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JNE45_RS00615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JNE45_RS00620	COG1045	serine acetyltransferase
JNE45_RS00625	COG0215	cysteine-tRNA ligase activity
JNE45_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JNE45_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNE45_RS00640	COG3688	RNA-binding protein containing a PIN domain
JNE45_RS00645	COG1595	DNA-templated transcription, initiation
JNE45_RS00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE45_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JNE45_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
JNE45_RS00670	COG0081	regulation of translation
JNE45_RS00675	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JNE45_RS00680	COG0222	ribosome binding
JNE45_RS00685	COG2813	Specifically methylates the guanine in position
JNE45_RS00690	COG0085	RNA polymerase activity
JNE45_RS00695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JNE45_RS00700	COG1358	cellular component organization or biogenesis
JNE45_RS00705	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JNE45_RS00710	COG0049	tRNA binding
JNE45_RS00715	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JNE45_RS00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JNE45_RS00725	COG0596	Alpha beta hydrolase
JNE45_RS00735	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JNE45_RS00740	COG0088	Forms part of the polypeptide exit tunnel
JNE45_RS00745	COG0089	rRNA binding
JNE45_RS00750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JNE45_RS00755	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JNE45_RS00760	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JNE45_RS00765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JNE45_RS00775	COG0255	Belongs to the universal ribosomal protein uL29 family
JNE45_RS00780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JNE45_RS00785	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JNE45_RS00790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JNE45_RS00795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JNE45_RS00800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JNE45_RS00805	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JNE45_RS00810	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JNE45_RS00815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JNE45_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JNE45_RS00825	COG1841	ribosomal large subunit assembly
JNE45_RS00830	COG0200	Binds to the 23S rRNA
JNE45_RS00835	COG0201	protein transport
JNE45_RS00840	COG0563	adenylate kinase activity
JNE45_RS00845	COG0024	Methionine aminopeptidase
JNE45_RS00850	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JNE45_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JNE45_RS00860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JNE45_RS00865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JNE45_RS00870	COG0202	RNA polymerase activity
JNE45_RS00875	COG0203	ribosomal protein L17
JNE45_RS00880	COG1122	ATPase activity
JNE45_RS00885	COG1122	ATPase activity
JNE45_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE45_RS00895	COG0101	tRNA pseudouridine synthase activity
JNE45_RS00900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JNE45_RS00905	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JNE45_RS00915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS00940	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS00945	COG0489	protein tyrosine kinase activity
JNE45_RS00955	COG2194	sulfuric ester hydrolase activity
JNE45_RS00960	COG0726	polysaccharide deacetylase
JNE45_RS00990	COG0385	Bile acid
JNE45_RS00995	COG3876	Protein conserved in bacteria
JNE45_RS01000	COG1472	Belongs to the glycosyl hydrolase 3 family
JNE45_RS01005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JNE45_RS01010	COG1263	PTS System
JNE45_RS01010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS01015	COG1737	Transcriptional regulator
JNE45_RS01020	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JNE45_RS01055	COG1595	DNA-templated transcription, initiation
JNE45_RS01060	COG5662	AntiSigma factor
JNE45_RS01065	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JNE45_RS01070	COG4856	YbbR-like protein
JNE45_RS01075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JNE45_RS01080	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JNE45_RS01085	COG0745	RESPONSE REGULATOR receiver
JNE45_RS01090	COG2205	protein histidine kinase activity
JNE45_RS01095	COG1131	(ABC) transporter
JNE45_RS01125	COG1131	(ABC) transporter
JNE45_RS01140	COG1131	(ABC) transporter
JNE45_RS01150	COG1413	lyase activity
JNE45_RS01160	COG2311	Membrane
JNE45_RS01190	COG1131	(ABC) transporter
JNE45_RS01205	COG1113	amino acid transport
JNE45_RS01210	COG0584	glycerophosphoryl diester phosphodiesterase
JNE45_RS01215	COG2271	Major facilitator Superfamily
JNE45_RS01225	COG1331	Highly conserved protein containing a thioredoxin domain
JNE45_RS01230	COG1331	Highly conserved protein containing a thioredoxin domain
JNE45_RS01245	COG1331	Highly conserved protein containing a thioredoxin domain
JNE45_RS01250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JNE45_RS01270	COG1937	Protein conserved in bacteria
JNE45_RS01275	COG2210	Belongs to the sulfur carrier protein TusA family
JNE45_RS01280	COG1054	Belongs to the UPF0176 family
JNE45_RS01285	COG0425	Belongs to the sulfur carrier protein TusA family
JNE45_RS01285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE45_RS01290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE45_RS01290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE45_RS01295	COG0425	Belongs to the sulfur carrier protein TusA family
JNE45_RS01300	COG0730	response to heat
JNE45_RS01310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNE45_RS01315	COG2814	Major facilitator Superfamily
JNE45_RS01325	COG1846	Transcriptional regulator
JNE45_RS01335	COG1683	Conserved Protein
JNE45_RS01345	COG0656	L-ascorbic acid biosynthetic process
JNE45_RS01350	COG0371	Dehydrogenase
JNE45_RS01355	COG1054	Belongs to the UPF0176 family
JNE45_RS01360	COG0531	amino acid
JNE45_RS01370	COG3711	transcriptional antiterminator
JNE45_RS01375	COG1263	PTS System
JNE45_RS01375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS01375	COG2190	(PTS) system
JNE45_RS01380	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS01400	COG3711	transcriptional antiterminator
JNE45_RS01400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS01405	COG1940	carbohydrate kinase activity
JNE45_RS01410	COG0383	alpha-mannosidase activity
JNE45_RS01415	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS01420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS01430	COG1404	Belongs to the peptidase S8 family
JNE45_RS01450	COG0833	amino acid
JNE45_RS01455	COG2040	homocysteine
JNE45_RS01460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE45_RS01465	COG1695	Transcriptional regulator
JNE45_RS01480	COG2814	Major facilitator Superfamily
JNE45_RS01485	COG0456	acetyltransferase
JNE45_RS01500	COG1404	Belongs to the peptidase S8 family
JNE45_RS01510	COG1309	transcriptional regulator
JNE45_RS01515	COG1917	Cupin 2, conserved barrel domain protein
JNE45_RS01520	COG1063	alcohol dehydrogenase
JNE45_RS01525	COG1846	Transcriptional regulator
JNE45_RS01530	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS01535	COG0531	amino acid
JNE45_RS01545	COG0596	Alpha beta hydrolase
JNE45_RS01550	COG1115	amino acid carrier protein
JNE45_RS01555	COG2066	Belongs to the glutaminase family
JNE45_RS01560	COG4191	Histidine kinase
JNE45_RS01565	COG0784	Response regulator, receiver
JNE45_RS01570	COG1405	negative regulation of cell septum assembly
JNE45_RS01570	COG3012	SEC-C Motif Domain Protein
JNE45_RS01580	COG2197	response regulator
JNE45_RS01585	COG4585	Histidine kinase
JNE45_RS01595	COG0667	Aldo Keto reductase
JNE45_RS01600	COG3290	protein histidine kinase activity
JNE45_RS01605	COG3279	Response regulator of the LytR AlgR family
JNE45_RS01610	COG4555	ABC transporter
JNE45_RS01615	COG1668	transmembrane transport
JNE45_RS01630	COG1404	Belongs to the peptidase S8 family
JNE45_RS01640	COG3773	Cell wall hydrolase
JNE45_RS01645	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS01655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS01660	COG2310	stress, protein
JNE45_RS01665	COG2310	stress, protein
JNE45_RS01670	COG2310	stress, protein
JNE45_RS01675	COG0861	Integral membrane protein TerC family
JNE45_RS01705	COG3853	Toxic anion resistance protein (TelA)
JNE45_RS01710	COG4175	Glycine betaine
JNE45_RS01710	COG0517	IMP dehydrogenase activity
JNE45_RS01715	COG4176	ABC-type proline glycine betaine transport system permease component
JNE45_RS01720	COG2113	Glycine betaine
JNE45_RS01735	COG1473	amidohydrolase
JNE45_RS01740	COG1288	antiporter activity
JNE45_RS01745	COG0039	L-malate dehydrogenase activity
JNE45_RS01750	COG1620	l-lactate permease
JNE45_RS01755	COG1609	Transcriptional regulator
JNE45_RS01760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE45_RS01765	COG0561	phosphatase activity
JNE45_RS01770	COG0673	inositol 2-dehydrogenase activity
JNE45_RS01775	COG0738	Major facilitator superfamily
JNE45_RS01780	COG1280	lysine exporter protein (LysE YggA)
JNE45_RS01790	COG3403	YqcI/YcgG family
JNE45_RS01795	COG1113	amino acid transport
JNE45_RS01800	COG3665	Urea carboxylase-associated protein
JNE45_RS01805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JNE45_RS01825	COG3209	COG3209 Rhs family protein
JNE45_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS01840	COG0710	3-dehydroquinate dehydratase activity
JNE45_RS01845	COG0028	Belongs to the TPP enzyme family
JNE45_RS01855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JNE45_RS01860	COG2271	Major facilitator Superfamily
JNE45_RS01875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JNE45_RS01880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JNE45_RS01890	COG0477	Major facilitator Superfamily
JNE45_RS01895	COG2226	methyltransferase
JNE45_RS01900	COG0583	DNA-binding transcription factor activity
JNE45_RS01905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JNE45_RS01910	COG3458	cephalosporin-C deacetylase activity
JNE45_RS01920	COG3541	Predicted nucleotidyltransferase
JNE45_RS01925	COG0506	proline dehydrogenase activity
JNE45_RS01930	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS01935	COG2508	Transcriptional regulator
JNE45_RS01940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JNE45_RS01945	COG0765	amino acid transport
JNE45_RS01950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS01960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JNE45_RS01965	COG1522	sequence-specific DNA binding
JNE45_RS01970	COG2746	aminoglycoside 3-N-acetyltransferase activity
JNE45_RS01980	COG0840	transmembrane signaling receptor activity
JNE45_RS01980	COG3290	protein histidine kinase activity
JNE45_RS01985	COG3209	COG3209 Rhs family protein
JNE45_RS02005	COG3842	ATPase activity
JNE45_RS02020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE45_RS02025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE45_RS02030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE45_RS02045	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JNE45_RS02050	COG0697	spore germination
JNE45_RS02055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS02065	COG2207	Transcriptional regulator
JNE45_RS02065	COG3708	Transcriptional regulator
JNE45_RS02075	COG2364	Membrane
JNE45_RS02085	COG3764	Sortase (surface protein transpeptidase)
JNE45_RS02090	COG2002	toxin-antitoxin pair type II binding
JNE45_RS02095	COG1126	abc transporter atp-binding protein
JNE45_RS02100	COG0765	amino acid transport
JNE45_RS02105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS02110	COG0412	Dienelactone hydrolase
JNE45_RS02115	COG0833	amino acid
JNE45_RS02120	COG3104	oligopeptide transport
JNE45_RS02125	COG5434	Belongs to the glycosyl hydrolase 28 family
JNE45_RS02130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS02135	COG0456	acetyltransferase
JNE45_RS02140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS02145	COG0765	amino acid transport
JNE45_RS02150	COG1126	abc transporter atp-binding protein
JNE45_RS02155	COG1473	amidohydrolase
JNE45_RS02160	COG2079	MmgE PrpD family protein
JNE45_RS02165	COG0745	RESPONSE REGULATOR receiver
JNE45_RS02170	COG5002	protein histidine kinase activity
JNE45_RS02170	COG3850	Histidine kinase
JNE45_RS02175	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS02180	COG0527	aspartate kinase activity
JNE45_RS02185	COG2814	Major facilitator Superfamily
JNE45_RS02190	COG1309	transcriptional regulator
JNE45_RS02200	COG0640	Transcriptional regulator
JNE45_RS02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS02210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JNE45_RS02215	COG0531	amino acid
JNE45_RS02220	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS02225	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE45_RS02230	COG4549	nuclear export factor GLE1
JNE45_RS02235	COG2372	response to copper ion
JNE45_RS02235	COG1276	copper resistance
JNE45_RS02240	COG2213	PTS system mannitol-specific
JNE45_RS02245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS02250	COG0246	Mannitol dehydrogenase
JNE45_RS02255	COG0840	transmembrane signaling receptor activity
JNE45_RS02275	COG0346	lactoylglutathione lyase activity
JNE45_RS02285	COG0561	phosphatase activity
JNE45_RS02290	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JNE45_RS02295	COG1914	H( )-stimulated, divalent metal cation uptake system
JNE45_RS02300	COG4336	lyase activity
JNE45_RS02305	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JNE45_RS02310	COG1984	allophanate hydrolase subunit 2
JNE45_RS02315	COG1414	Transcriptional regulator
JNE45_RS02320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JNE45_RS02325	COG2755	lipolytic protein G-D-S-L family
JNE45_RS02335	COG3711	transcriptional antiterminator
JNE45_RS02340	COG2226	methyltransferase
JNE45_RS02345	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS02350	COG3871	stress protein (general stress protein 26)
JNE45_RS02370	COG2814	Major facilitator Superfamily
JNE45_RS02375	COG1802	Transcriptional regulator
JNE45_RS02380	COG1917	Cupin 2, conserved barrel domain protein
JNE45_RS02380	COG2207	Transcriptional regulator
JNE45_RS02385	COG0697	spore germination
JNE45_RS02390	COG0473	3-isopropylmalate dehydrogenase activity
JNE45_RS02395	COG0551	DNA topoisomerase type I activity
JNE45_RS02395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JNE45_RS02400	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JNE45_RS02405	COG3706	GGDEF domain
JNE45_RS02410	COG5298	Protein conserved in bacteria
JNE45_RS02415	COG1215	transferase activity, transferring glycosyl groups
JNE45_RS02425	COG0531	amino acid
JNE45_RS02430	COG0028	Belongs to the TPP enzyme family
JNE45_RS02465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS02470	COG1914	H( )-stimulated, divalent metal cation uptake system
JNE45_RS02475	COG2261	transglycosylase associated protein
JNE45_RS02480	COG2217	Heavy metal translocating P-type atpase
JNE45_RS02485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JNE45_RS02490	COG3290	protein histidine kinase activity
JNE45_RS02495	COG4565	transcriptional regulatory protein
JNE45_RS02500	COG1301	dicarboxylic acid transport
JNE45_RS02505	COG0628	permease
JNE45_RS02510	COG1301	dicarboxylic acid transport
JNE45_RS02515	COG1131	(ABC) transporter
JNE45_RS02520	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JNE45_RS02535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS02540	COG1181	Belongs to the D-alanine--D-alanine ligase family
JNE45_RS02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JNE45_RS02560	COG0513	Belongs to the DEAD box helicase family
JNE45_RS02565	COG3402	PFAM membrane-flanked domain
JNE45_RS02570	COG3428	Bacterial PH domain
JNE45_RS02575	COG0705	Rhomboid family
JNE45_RS02580	COG0736	holo-[acyl-carrier-protein] synthase activity
JNE45_RS02585	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JNE45_RS02590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JNE45_RS02595	COG0864	Transcriptional regulator
JNE45_RS02600	COG2337	Toxic component of a toxin-antitoxin (TA) module
JNE45_RS02605	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS02610	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS02615	COG2172	sigma factor antagonist activity
JNE45_RS02620	COG2208	phosphoserine phosphatase activity
JNE45_RS02625	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS02630	COG2172	sigma factor antagonist activity
JNE45_RS02635	COG1191	sigma factor activity
JNE45_RS02640	COG2208	phosphoserine phosphatase activity
JNE45_RS02645	COG2183	response to ionizing radiation
JNE45_RS02655	COG3091	SprT-like family
JNE45_RS02660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE45_RS02665	COG0022	dehydrogenase e1 component
JNE45_RS02670	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS02675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE45_RS02680	COG3284	Transcriptional regulator
JNE45_RS02735	COG0456	acetyltransferase
JNE45_RS02735	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JNE45_RS02740	COG1278	Cold shock
JNE45_RS02745	COG1329	Transcriptional regulator
JNE45_RS02750	COG1064	alcohol dehydrogenase
JNE45_RS02755	COG0789	Transcriptional regulator
JNE45_RS02770	COG0477	Major facilitator Superfamily
JNE45_RS02775	COG0657	acetylesterase activity
JNE45_RS02785	COG4221	oxidoreductase activity
JNE45_RS02790	COG0252	asparaginase activity
JNE45_RS02810	COG2814	Major facilitator Superfamily
JNE45_RS02815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS02845	COG1309	transcriptional regulator
JNE45_RS02850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JNE45_RS02855	COG1846	Transcriptional regulator
JNE45_RS02860	COG0778	Nitroreductase
JNE45_RS02875	COG1396	sequence-specific DNA binding
JNE45_RS02885	COG0456	acetyltransferase
JNE45_RS02895	COG4122	O-methyltransferase activity
JNE45_RS02905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JNE45_RS02910	COG0697	spore germination
JNE45_RS02920	COG1301	dicarboxylic acid transport
JNE45_RS02960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JNE45_RS02965	COG0802	atpase or kinase
JNE45_RS02970	COG1214	PFAM Peptidase M22, glycoprotease
JNE45_RS02975	COG0456	acetyltransferase
JNE45_RS02980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JNE45_RS02985	COG0488	(ABC) transporter
JNE45_RS02990	COG0315	cyclic pyranopterin monophosphate synthase activity
JNE45_RS02995	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JNE45_RS03000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JNE45_RS03005	COG0805	protein transport
JNE45_RS03020	COG1266	CAAX protease self-immunity
JNE45_RS03025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JNE45_RS03030	COG0459	protein refolding
JNE45_RS03040	COG1846	Transcriptional regulator
JNE45_RS03045	COG0456	acetyltransferase
JNE45_RS03050	COG2808	Putative FMN-binding domain
JNE45_RS03070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JNE45_RS03075	COG0823	Involved in the tonB-independent uptake of proteins
JNE45_RS03085	COG2132	Multicopper oxidase
JNE45_RS03090	COG1113	amino acid transport
JNE45_RS03095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JNE45_RS03100	COG0714	Associated with various cellular activities
JNE45_RS03105	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JNE45_RS03110	COG1305	Transglutaminase-like
JNE45_RS03115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JNE45_RS03115	COG0519	Catalyzes the synthesis of GMP from XMP
JNE45_RS03130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JNE45_RS03140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE45_RS03145	COG2207	Transcriptional regulator
JNE45_RS03180	COG1595	DNA-templated transcription, initiation
JNE45_RS03190	COG2814	Major facilitator Superfamily
JNE45_RS03195	COG0583	DNA-binding transcription factor activity
JNE45_RS03200	COG2252	PERMEase
JNE45_RS03215	COG3064	Membrane
JNE45_RS03220	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
JNE45_RS03230	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JNE45_RS03235	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JNE45_RS03240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JNE45_RS03245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JNE45_RS03250	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNE45_RS03255	COG0047	phosphoribosylformylglycinamidine synthase activity
JNE45_RS03260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JNE45_RS03265	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JNE45_RS03270	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JNE45_RS03275	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JNE45_RS03280	COG0138	bifunctional purine biosynthesis protein purh
JNE45_RS03285	COG0151	Belongs to the GarS family
JNE45_RS03305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JNE45_RS03310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JNE45_RS03315	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JNE45_RS03320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JNE45_RS03330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JNE45_RS03335	COG4496	protein, YerC YecD
JNE45_RS03340	COG0069	glutamate synthase activity
JNE45_RS03355	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JNE45_RS03360	COG0210	DNA helicase
JNE45_RS03365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JNE45_RS03370	COG4851	CamS sex pheromone cAM373 precursor
JNE45_RS03375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE45_RS03380	COG1285	pathogenesis
JNE45_RS03385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE45_RS03390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNE45_RS03395	COG0154	amidase activity
JNE45_RS03400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JNE45_RS03405	COG1309	transcriptional regulator
JNE45_RS03410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JNE45_RS03415	COG1957	nucleoside hydrolase
JNE45_RS03420	COG1597	lipid kinase activity
JNE45_RS03425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNE45_RS03435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JNE45_RS03445	COG1737	Transcriptional regulator
JNE45_RS03450	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS03450	COG1263	PTS System
JNE45_RS03455	COG1486	melibiose metabolic process
JNE45_RS03465	COG1959	2 iron, 2 sulfur cluster binding
JNE45_RS03470	COG0492	ferredoxin-NADP+ reductase activity
JNE45_RS03485	COG1486	melibiose metabolic process
JNE45_RS03495	COG2211	Major facilitator Superfamily
JNE45_RS03525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JNE45_RS03530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE45_RS03535	COG1442	glycosyl transferase family 8
JNE45_RS03540	COG1216	Glycosyl transferase, family 2
JNE45_RS03545	COG1442	glycosyl transferase family 8
JNE45_RS03550	COG2223	nitrite transmembrane transporter activity
JNE45_RS03560	COG0471	metal ion transport
JNE45_RS03575	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE45_RS03590	COG0531	amino acid
JNE45_RS03595	COG0463	Glycosyl transferase, family 2
JNE45_RS03600	COG0488	(ABC) transporter
JNE45_RS03605	COG1469	GTP cyclohydrolase I activity
JNE45_RS03610	COG0789	Transcriptional regulator
JNE45_RS03615	COG2814	Major facilitator Superfamily
JNE45_RS03620	COG0488	(ABC) transporter
JNE45_RS03625	COG0513	Belongs to the DEAD box helicase family
JNE45_RS03630	COG2130	NADP-dependent
JNE45_RS03650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS03650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS03655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JNE45_RS03665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE45_RS03665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE45_RS03675	COG3290	protein histidine kinase activity
JNE45_RS03680	COG4565	transcriptional regulatory protein
JNE45_RS03685	COG3181	Tripartite tricarboxylate transporter family receptor
JNE45_RS03690	COG2851	Citrate transporter
JNE45_RS03700	COG3479	Phenolic acid decarboxylase
JNE45_RS03705	COG1695	Transcriptional regulator
JNE45_RS03710	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JNE45_RS03715	COG0477	Major facilitator Superfamily
JNE45_RS03720	COG0583	DNA-binding transcription factor activity
JNE45_RS03730	COG1254	Belongs to the acylphosphatase family
JNE45_RS03735	COG2258	MOSC domain
JNE45_RS03750	COG0024	Methionine aminopeptidase
JNE45_RS03755	COG1263	PTS System
JNE45_RS03755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS03760	COG3739	integral membrane protein
JNE45_RS03780	COG1368	sulfuric ester hydrolase activity
JNE45_RS03785	COG0076	glutamate decarboxylase activity
JNE45_RS03800	COG1263	PTS System
JNE45_RS03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS03805	COG0366	Alpha amylase catalytic
JNE45_RS03810	COG2188	Transcriptional regulator
JNE45_RS03820	COG0737	Belongs to the 5'-nucleotidase family
JNE45_RS03825	COG0693	protein deglycase activity
JNE45_RS03830	COG4840	Belongs to the UPF0435 family
JNE45_RS03835	COG1115	amino acid carrier protein
JNE45_RS03840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JNE45_RS03845	COG4980	gas vesicle protein
JNE45_RS03850	COG1295	ribonuclease BN
JNE45_RS03855	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS03860	COG0477	Major facilitator Superfamily
JNE45_RS03870	COG0387	Pfam Sodium calcium exchanger
JNE45_RS03880	COG0217	transcriptional regulatory protein
JNE45_RS03885	COG0668	transmembrane transport
JNE45_RS03890	COG0535	radical SAM domain protein
JNE45_RS03900	COG0726	polysaccharide deacetylase
JNE45_RS03910	COG0598	Magnesium transport protein CorA
JNE45_RS03920	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JNE45_RS03925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JNE45_RS03950	COG0789	Transcriptional regulator
JNE45_RS03955	COG2814	Major facilitator Superfamily
JNE45_RS03975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNE45_RS04015	COG2076	Multidrug Resistance protein
JNE45_RS04020	COG2076	Multidrug Resistance protein
JNE45_RS04025	COG1309	transcriptional regulator
JNE45_RS04035	COG4637	Psort location Cytoplasmic, score
JNE45_RS04040	COG2755	lipolytic protein G-D-S-L family
JNE45_RS04045	COG0492	ferredoxin-NADP+ reductase activity
JNE45_RS04050	COG2169	Transcriptional regulator
JNE45_RS04055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS04060	COG1132	(ABC) transporter
JNE45_RS04065	COG1742	UPF0060 membrane protein
JNE45_RS04070	COG1595	DNA-templated transcription, initiation
JNE45_RS04090	COG2318	DinB family
JNE45_RS04100	COG1846	Transcriptional regulator
JNE45_RS04105	COG0392	lysyltransferase activity
JNE45_RS04105	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JNE45_RS04125	COG0778	Nitroreductase
JNE45_RS04140	COG1090	epimerase
JNE45_RS04145	COG2137	regulation of response to DNA damage stimulus
JNE45_RS04170	COG0463	Glycosyl transferase, family 2
JNE45_RS04175	COG4485	Bacterial membrane protein, YfhO
JNE45_RS04180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JNE45_RS04195	COG2140	Oxalate decarboxylase
JNE45_RS04205	COG1191	sigma factor activity
JNE45_RS04250	COG1988	membrane-bound metal-dependent
JNE45_RS04255	COG1194	a g-specific adenine glycosylase
JNE45_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS04280	COG3557	Belongs to the UPF0374 family
JNE45_RS04285	COG1132	(ABC) transporter
JNE45_RS04290	COG0444	Belongs to the ABC transporter superfamily
JNE45_RS04295	COG4608	Belongs to the ABC transporter superfamily
JNE45_RS04300	COG0747	negative chemotaxis
JNE45_RS04305	COG0601	transmembrane transport
JNE45_RS04310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE45_RS04315	COG4129	membrane
JNE45_RS04320	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JNE45_RS04325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JNE45_RS04330	COG0735	belongs to the Fur family
JNE45_RS04480	COG1368	sulfuric ester hydrolase activity
JNE45_RS04485	COG0681	Belongs to the peptidase S26 family
JNE45_RS04490	COG2873	o-acetylhomoserine
JNE45_RS04500	COG1116	anion transmembrane transporter activity
JNE45_RS04505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JNE45_RS04510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JNE45_RS04525	COG1131	(ABC) transporter
JNE45_RS04555	COG3382	B3 4 domain protein
JNE45_RS04560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JNE45_RS04570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JNE45_RS04575	COG2766	serine protein kinase
JNE45_RS04580	COG2718	Belongs to the UPF0229 family
JNE45_RS04585	COG1566	PFAM secretion protein HlyD family protein
JNE45_RS04590	COG2814	Major facilitator Superfamily
JNE45_RS04595	COG0655	NAD(P)H dehydrogenase (quinone) activity
JNE45_RS04605	COG1278	Cold shock
JNE45_RS04610	COG3706	GGDEF domain
JNE45_RS04635	COG5577	PFAM Coat F domain
JNE45_RS04640	COG5002	protein histidine kinase activity
JNE45_RS04645	COG1525	nuclease
JNE45_RS04645	COG0737	Belongs to the 5'-nucleotidase family
JNE45_RS04645	COG4085	toxin activity
JNE45_RS04650	COG3764	Sortase (surface protein transpeptidase)
JNE45_RS04655	COG0564	pseudouridine synthase activity
JNE45_RS04665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JNE45_RS04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JNE45_RS04670	COG3153	acetyltransferase
JNE45_RS04685	COG3835	regulator
JNE45_RS04690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JNE45_RS04695	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JNE45_RS04700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JNE45_RS04705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JNE45_RS04710	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JNE45_RS04715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JNE45_RS04720	COG2203	Gaf domain
JNE45_RS04720	COG4585	Histidine kinase
JNE45_RS04725	COG2197	response regulator
JNE45_RS04740	COG0753	catalase activity
JNE45_RS04745	COG1959	2 iron, 2 sulfur cluster binding
JNE45_RS04750	COG1017	nitric oxide dioxygenase activity
JNE45_RS04750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JNE45_RS04755	COG2719	SpoVR family
JNE45_RS04760	COG1785	Belongs to the alkaline phosphatase family
JNE45_RS04765	COG1388	LysM domain
JNE45_RS04765	COG0791	NLP P60 protein
JNE45_RS04770	COG0531	amino acid
JNE45_RS04785	COG1595	DNA-templated transcription, initiation
JNE45_RS04790	COG0204	Acyl-transferase
JNE45_RS04795	COG1253	flavin adenine dinucleotide binding
JNE45_RS04800	COG0789	Transcriptional regulator
JNE45_RS04805	COG1253	flavin adenine dinucleotide binding
JNE45_RS04815	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JNE45_RS04820	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JNE45_RS04825	COG0584	glycerophosphoryl diester phosphodiesterase
JNE45_RS04835	COG0668	transmembrane transport
JNE45_RS04840	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JNE45_RS04850	COG0726	polysaccharide deacetylase
JNE45_RS04855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE45_RS04860	COG0589	response to stress
JNE45_RS04865	COG1132	(ABC) transporter
JNE45_RS04870	COG1132	(ABC) transporter
JNE45_RS04880	COG0702	epimerase
JNE45_RS04890	COG3842	ATPase activity
JNE45_RS04895	COG2508	Transcriptional regulator
JNE45_RS04905	COG0189	ligase activity
JNE45_RS04910	COG0189	ligase activity
JNE45_RS04915	COG4399	Belongs to the UPF0754 family
JNE45_RS04920	COG3679	Belongs to the UPF0342 family
JNE45_RS04925	COG0561	phosphatase activity
JNE45_RS04930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JNE45_RS04940	COG0475	glutathione-regulated potassium exporter activity
JNE45_RS04945	COG0490	domain, Protein
JNE45_RS04955	COG1024	Enoyl-CoA hydratase
JNE45_RS04965	COG0420	3'-5' exonuclease activity
JNE45_RS04970	COG4717	serine-type aminopeptidase activity
JNE45_RS04975	COG3481	metal-dependent phosphohydrolase, HD sub domain
JNE45_RS04985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JNE45_RS05010	COG1846	Transcriptional regulator
JNE45_RS05015	COG4980	gas vesicle protein
JNE45_RS05030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JNE45_RS05035	COG0537	adenosine 5'-monophosphoramidase activity
JNE45_RS05040	COG1131	(ABC) transporter
JNE45_RS05045	COG4473	ABC transporter
JNE45_RS05055	COG1473	amidohydrolase
JNE45_RS05065	COG2329	Antibiotic biosynthesis monooxygenase
JNE45_RS05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE45_RS05075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JNE45_RS05080	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JNE45_RS05085	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JNE45_RS05090	COG1309	transcriptional regulator
JNE45_RS05095	COG1511	domain protein
JNE45_RS05100	COG1363	Peptidase, m42
JNE45_RS05105	COG1301	dicarboxylic acid transport
JNE45_RS05115	COG1234	tRNA 3'-trailer cleavage
JNE45_RS05120	COG0095	Lipoate-protein ligase
JNE45_RS05125	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS05135	COG0501	Belongs to the peptidase M48B family
JNE45_RS05140	COG1404	Belongs to the peptidase S8 family
JNE45_RS05145	COG0406	alpha-ribazole phosphatase activity
JNE45_RS05150	COG0840	transmembrane signaling receptor activity
JNE45_RS05155	COG0723	plastoquinol--plastocyanin reductase activity
JNE45_RS05155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JNE45_RS05160	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS05170	COG4903	ComK protein
JNE45_RS05180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS05185	COG2814	Major facilitator Superfamily
JNE45_RS05190	COG2732	(Barnase) inhibitor
JNE45_RS05195	COG1316	TRANSCRIPTIONal
JNE45_RS05205	COG0398	Pfam SNARE associated Golgi protein
JNE45_RS05210	COG0681	Belongs to the peptidase S26 family
JNE45_RS05215	COG3180	Ammonia monooxygenase
JNE45_RS05225	COG0501	Belongs to the peptidase M48B family
JNE45_RS05230	COG2259	Doxx family
JNE45_RS05235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JNE45_RS05240	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JNE45_RS05245	COG1074	ATP-dependent DNA helicase activity
JNE45_RS05250	COG0420	3'-5' exonuclease activity
JNE45_RS05255	COG0419	ATPase involved in DNA repair
JNE45_RS05260	COG1403	HNH endonuclease
JNE45_RS05300	COG5337	Spore coat protein CotH
JNE45_RS05310	COG0179	Fumarylacetoacetate (FAA) hydrolase
JNE45_RS05325	COG0367	asparagine synthase
JNE45_RS05340	COG1562	ergosterol biosynthetic process
JNE45_RS05345	COG0534	Mate efflux family protein
JNE45_RS05350	COG2207	Transcriptional regulator
JNE45_RS05350	COG1917	Cupin 2, conserved barrel domain protein
JNE45_RS05380	COG0076	glutamate decarboxylase activity
JNE45_RS05415	COG0646	methionine synthase
JNE45_RS05415	COG1410	methionine synthase
JNE45_RS05420	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JNE45_RS05420	COG0646	methionine synthase
JNE45_RS05425	COG1666	GTP binding
JNE45_RS05430	COG2996	Protein conserved in bacteria
JNE45_RS05435	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE45_RS05440	COG0840	transmembrane signaling receptor activity
JNE45_RS05445	COG1307	EDD domain protein, DegV family
JNE45_RS05450	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE45_RS05470	COG0561	phosphatase activity
JNE45_RS05475	COG1073	alpha beta
JNE45_RS05480	COG2151	metal-sulfur cluster biosynthetic enzyme
JNE45_RS05485	COG0277	FAD linked oxidase domain protein
JNE45_RS05490	COG2271	Major facilitator Superfamily
JNE45_RS05495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JNE45_RS05500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JNE45_RS05505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JNE45_RS05510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JNE45_RS05515	COG0505	Belongs to the CarA family
JNE45_RS05520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JNE45_RS05525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JNE45_RS05535	COG2814	Major facilitator Superfamily
JNE45_RS05545	COG2267	carboxylic ester hydrolase activity
JNE45_RS05555	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE45_RS05570	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JNE45_RS05575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JNE45_RS05580	COG5504	Zn-dependent protease
JNE45_RS05585	COG0444	Belongs to the ABC transporter superfamily
JNE45_RS05590	COG4608	Belongs to the ABC transporter superfamily
JNE45_RS05600	COG0601	transmembrane transport
JNE45_RS05605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE45_RS05615	COG0180	Tryptophanyl-tRNA synthetase
JNE45_RS05625	COG4166	transmembrane transport
JNE45_RS05630	COG0601	transmembrane transport
JNE45_RS05635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE45_RS05640	COG0444	Belongs to the ABC transporter superfamily
JNE45_RS05645	COG4608	Belongs to the ABC transporter superfamily
JNE45_RS05655	COG0456	acetyltransferase
JNE45_RS05660	COG1393	Belongs to the ArsC family
JNE45_RS05665	COG0861	Integral membrane protein TerC family
JNE45_RS05670	COG4862	establishment of competence for transformation
JNE45_RS05675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE45_RS05685	COG1164	Oligoendopeptidase f
JNE45_RS05695	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JNE45_RS05700	COG2346	COG2346, Truncated hemoglobins
JNE45_RS05705	COG0741	lytic transglycosylase activity
JNE45_RS05710	COG4116	CYTH
JNE45_RS05720	COG2357	RelA SpoT domain protein
JNE45_RS05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JNE45_RS05730	COG0564	pseudouridine synthase activity
JNE45_RS05735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JNE45_RS05740	COG0475	glutathione-regulated potassium exporter activity
JNE45_RS05740	COG0569	domain protein
JNE45_RS05745	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JNE45_RS05750	COG0352	thiamine-phosphate diphosphorylase activity
JNE45_RS05760	COG2104	thiamine diphosphate biosynthetic process
JNE45_RS05765	COG2022	thiamine diphosphate biosynthetic process
JNE45_RS05770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JNE45_RS05775	COG0351	phosphomethylpyrimidine kinase
JNE45_RS05780	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JNE45_RS05835	COG0210	DNA helicase
JNE45_RS05855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JNE45_RS05860	COG2382	esterase
JNE45_RS05865	COG0626	cystathionine gamma-synthase activity
JNE45_RS05870	COG0626	cystathionine gamma-synthase activity
JNE45_RS05885	COG0384	phenazine biosynthesis protein PhzF
JNE45_RS05890	COG0457	Tetratricopeptide repeat
JNE45_RS05895	COG0825	malonyl-CoA metabolic process
JNE45_RS05915	COG2807	transmembrane transport
JNE45_RS05925	COG0583	DNA-binding transcription factor activity
JNE45_RS05940	COG0457	Tetratricopeptide repeat
JNE45_RS05955	COG3173	Aminoglycoside phosphotransferase
JNE45_RS05960	COG0583	DNA-binding transcription factor activity
JNE45_RS05980	COG0583	DNA-binding transcription factor activity
JNE45_RS05985	COG2807	transmembrane transport
JNE45_RS06005	COG0457	Tetratricopeptide repeat
JNE45_RS06035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JNE45_RS06055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE45_RS06060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE45_RS06065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE45_RS06085	COG4195	phage-related replication protein
JNE45_RS06090	COG2856	Zn peptidase
JNE45_RS06095	COG3409	Peptidoglycan-binding domain 1 protein
JNE45_RS06095	COG5632	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS06115	COG0306	phosphate transporter
JNE45_RS06120	COG1392	Phosphate transport regulator
JNE45_RS06130	COG0405	Gamma-glutamyltransferase
JNE45_RS06135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JNE45_RS06145	COG4208	sulfate ABC transporter
JNE45_RS06150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JNE45_RS06160	COG3775	system Galactitol-specific IIC component
JNE45_RS06175	COG1063	alcohol dehydrogenase
JNE45_RS06180	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE45_RS06185	COG0022	dehydrogenase e1 component
JNE45_RS06185	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS06190	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE45_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS06205	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS06210	COG2390	Transcriptional regulator
JNE45_RS06220	COG0531	amino acid
JNE45_RS06225	COG0346	lactoylglutathione lyase activity
JNE45_RS06230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE45_RS06235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE45_RS06240	COG2362	D-Aminopeptidase
JNE45_RS06245	COG0601	transmembrane transport
JNE45_RS06250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE45_RS06255	COG0444	Belongs to the ABC transporter superfamily
JNE45_RS06260	COG4166	transmembrane transport
JNE45_RS06265	COG1619	proteins homologs of microcin C7 resistance protein MccF
JNE45_RS06270	COG4948	Mandelate Racemase Muconate Lactonizing
JNE45_RS06275	COG0791	NLP P60 protein
JNE45_RS06280	COG4608	Belongs to the ABC transporter superfamily
JNE45_RS06285	COG1834	amidinotransferase
JNE45_RS06290	COG1607	acyl-coa hydrolase
JNE45_RS06295	COG1695	Transcriptional regulator
JNE45_RS06310	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS06325	COG2076	Multidrug Resistance protein
JNE45_RS06330	COG2076	Multidrug Resistance protein
JNE45_RS06340	COG0788	formyltetrahydrofolate deformylase activity
JNE45_RS06345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JNE45_RS06350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JNE45_RS06355	COG0457	Tetratricopeptide repeat
JNE45_RS06365	COG1764	response to oxidative stress
JNE45_RS06370	COG1846	Transcriptional regulator
JNE45_RS06375	COG1764	response to oxidative stress
JNE45_RS06380	COG0590	tRNA wobble adenosine to inosine editing
JNE45_RS06385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JNE45_RS06390	COG1404	Belongs to the peptidase S8 family
JNE45_RS06405	COG0745	RESPONSE REGULATOR receiver
JNE45_RS06410	COG3850	Histidine kinase
JNE45_RS06410	COG5002	protein histidine kinase activity
JNE45_RS06415	COG3212	peptidase
JNE45_RS06420	COG3212	peptidase
JNE45_RS06430	COG2239	Acts as a magnesium transporter
JNE45_RS06440	COG0583	DNA-binding transcription factor activity
JNE45_RS06450	COG0789	Transcriptional regulator
JNE45_RS06465	COG1846	Transcriptional regulator
JNE45_RS06470	COG5001	Diguanylate cyclase
JNE45_RS06470	COG3300	MHYT domain
JNE45_RS06475	COG0586	Pfam SNARE associated Golgi protein
JNE45_RS06480	COG0861	Integral membrane protein TerC family
JNE45_RS06485	COG1191	sigma factor activity
JNE45_RS06505	COG0501	Belongs to the peptidase M48B family
JNE45_RS06510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JNE45_RS06515	COG2323	membrane
JNE45_RS06530	COG3594	Acyltransferase
JNE45_RS06535	COG5002	protein histidine kinase activity
JNE45_RS06540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JNE45_RS06550	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JNE45_RS06555	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JNE45_RS06560	COG0436	Aminotransferase
JNE45_RS06565	COG1850	ribulose-bisphosphate carboxylase activity
JNE45_RS06570	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JNE45_RS06575	COG0235	Class ii aldolase
JNE45_RS06580	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JNE45_RS06590	COG3852	Histidine kinase
JNE45_RS06595	COG1846	Transcriptional regulator
JNE45_RS06600	COG1360	Flagellar Motor Protein
JNE45_RS06605	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JNE45_RS06610	COG0542	response to heat
JNE45_RS06615	COG3949	Membrane
JNE45_RS06620	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JNE45_RS06625	COG0720	synthase
JNE45_RS06630	COG0602	queuosine metabolic process
JNE45_RS06635	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JNE45_RS06645	COG4873	Protein conserved in bacteria
JNE45_RS06655	COG3773	Cell wall hydrolase
JNE45_RS06660	COG2244	polysaccharide biosynthetic process
JNE45_RS06665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS06670	COG2217	Heavy metal translocating P-type atpase
JNE45_RS06675	COG0006	proline dipeptidase activity
JNE45_RS06685	COG1609	Transcriptional regulator
JNE45_RS06690	COG3711	transcriptional antiterminator
JNE45_RS06695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS06695	COG1263	PTS System
JNE45_RS06695	COG2190	(PTS) system
JNE45_RS06700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS06705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JNE45_RS06715	COG1533	DNA photolyase activity
JNE45_RS06720	COG0840	transmembrane signaling receptor activity
JNE45_RS06730	COG2084	Dehydrogenase
JNE45_RS06735	COG2340	Cysteine-rich secretory protein family
JNE45_RS06740	COG0768	penicillin binding
JNE45_RS06745	COG4191	Histidine kinase
JNE45_RS06750	COG0436	Aminotransferase
JNE45_RS06755	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JNE45_RS06765	COG1714	RDD family
JNE45_RS06775	COG0835	chemotaxis
JNE45_RS06775	COG0784	Response regulator, receiver
JNE45_RS06795	COG2814	Major facilitator Superfamily
JNE45_RS06800	COG1376	ErfK ybiS ycfS ynhG family protein
JNE45_RS06805	COG1408	metallophosphoesterase
JNE45_RS06810	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS06815	COG2200	EAL domain
JNE45_RS06820	COG3546	catalase activity
JNE45_RS06825	COG4703	Protein of unknown function (DUF1797)
JNE45_RS06830	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JNE45_RS06840	COG0517	IMP dehydrogenase activity
JNE45_RS06845	COG0583	DNA-binding transcription factor activity
JNE45_RS06850	COG0716	FMN binding
JNE45_RS06860	COG0716	FMN binding
JNE45_RS06865	COG2171	N-acyltransferase activity
JNE45_RS06870	COG1473	amidohydrolase
JNE45_RS06880	COG0668	transmembrane transport
JNE45_RS06885	COG0450	alkyl hydroperoxide reductase
JNE45_RS06890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS06905	COG0746	molybdenum cofactor guanylyltransferase activity
JNE45_RS06910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JNE45_RS06915	COG0303	'Molybdopterin
JNE45_RS06920	COG1763	Mo-molybdopterin cofactor biosynthetic process
JNE45_RS06925	COG0314	molybdopterin synthase activity
JNE45_RS06930	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JNE45_RS06945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JNE45_RS06950	COG1136	(ABC) transporter
JNE45_RS06955	COG0577	efflux transmembrane transporter activity
JNE45_RS06960	COG1349	DNA-binding transcription factor activity
JNE45_RS06965	COG1105	Belongs to the carbohydrate kinase PfkB family
JNE45_RS06970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS06970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS06970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS06975	COG0681	Belongs to the peptidase S26 family
JNE45_RS06985	COG0488	(ABC) transporter
JNE45_RS06990	COG2309	aminopeptidase activity
JNE45_RS07000	COG1077	Cell shape determining protein MreB Mrl
JNE45_RS07005	COG2002	toxin-antitoxin pair type II binding
JNE45_RS07010	COG3852	Histidine kinase
JNE45_RS07015	COG2105	PFAM AIG2 family protein
JNE45_RS07015	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JNE45_RS07020	COG0569	domain protein
JNE45_RS07025	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JNE45_RS07030	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNE45_RS07035	COG5503	Protein of unknown function (DUF1447)
JNE45_RS07040	COG0561	phosphatase activity
JNE45_RS07045	COG0242	peptide deformylase activity
JNE45_RS07060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE45_RS07065	COG0022	dehydrogenase e1 component
JNE45_RS07070	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS07075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE45_RS07080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS07090	COG1982	Orn Lys Arg decarboxylase major
JNE45_RS07095	COG4476	Belongs to the UPF0223 family
JNE45_RS07100	COG4493	Belongs to the UPF0637 family
JNE45_RS07110	COG0483	inositol monophosphate 1-phosphatase activity
JNE45_RS07125	COG1595	DNA-templated transcription, initiation
JNE45_RS07145	COG1217	gtp-binding protein TYPA
JNE45_RS07155	COG4896	Protein conserved in bacteria
JNE45_RS07165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JNE45_RS07170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JNE45_RS07175	COG2066	Belongs to the glutaminase family
JNE45_RS07180	COG4838	Belongs to the UPF0358 family
JNE45_RS07185	COG0772	Belongs to the SEDS family
JNE45_RS07190	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JNE45_RS07195	COG0415	Belongs to the DNA photolyase family
JNE45_RS07200	COG1612	heme a metabolic process
JNE45_RS07205	COG0109	protoheme IX farnesyltransferase activity
JNE45_RS07210	COG2010	Cytochrome c
JNE45_RS07210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JNE45_RS07215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JNE45_RS07220	COG1845	cytochrome c oxidase, subunit III
JNE45_RS07225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JNE45_RS07230	COG3336	cytochrome c oxidase
JNE45_RS07240	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JNE45_RS07245	COG2340	Cysteine-rich secretory protein family
JNE45_RS07265	COG3679	Belongs to the UPF0342 family
JNE45_RS07270	COG4471	UPF0298 protein
JNE45_RS07275	COG0742	ribosomal rna small subunit methyltransferase
JNE45_RS07280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JNE45_RS07285	COG3314	Sporulation integral membrane protein YlbJ
JNE45_RS07290	COG1752	Esterase of the alpha-beta hydrolase superfamily
JNE45_RS07295	COG3480	Lon protease (S16) C-terminal proteolytic domain
JNE45_RS07305	COG1399	metal-binding, possibly nucleic acid-binding protein
JNE45_RS07310	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JNE45_RS07320	COG0454	-acetyltransferase
JNE45_RS07325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JNE45_RS07330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JNE45_RS07335	COG2001	Belongs to the MraZ family
JNE45_RS07340	COG0275	rRNA processing
JNE45_RS07345	COG4839	cell division protein FtsL
JNE45_RS07350	COG0768	penicillin binding
JNE45_RS07355	COG0768	penicillin binding
JNE45_RS07360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JNE45_RS07365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JNE45_RS07370	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JNE45_RS07375	COG0772	Belongs to the SEDS family
JNE45_RS07380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JNE45_RS07385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JNE45_RS07390	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JNE45_RS07395	COG3879	Bacterial protein of unknown function (DUF881)
JNE45_RS07400	COG3879	Bacterial protein of unknown function (DUF881)
JNE45_RS07405	COG3856	small basic protein
JNE45_RS07410	COG0849	cell division
JNE45_RS07415	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JNE45_RS07420	COG1404	Belongs to the peptidase S8 family
JNE45_RS07420	COG4412	M6 family metalloprotease domain protein
JNE45_RS07430	COG1191	sigma factor activity
JNE45_RS07435	COG1191	sigma factor activity
JNE45_RS07440	COG2390	Transcriptional regulator
JNE45_RS07455	COG3730	PTS system glucitol sorbitol-specific
JNE45_RS07460	COG3732	PTS system glucitol sorbitol-specific
JNE45_RS07470	COG1119	ATPase activity
JNE45_RS07475	COG1873	PFAM PRC-barrel domain
JNE45_RS07480	COG1496	oxidoreductase activity
JNE45_RS07485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JNE45_RS07490	COG1799	cell septum assembly
JNE45_RS07495	COG0762	integral membrane protein
JNE45_RS07500	COG2302	S4 RNA-binding domain
JNE45_RS07505	COG3599	regulation of cell shape
JNE45_RS07510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JNE45_RS07515	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE45_RS07520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JNE45_RS07525	COG0564	pseudouridine synthase activity
JNE45_RS07530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JNE45_RS07535	COG2233	PERMEase
JNE45_RS07540	COG0540	Belongs to the ATCase OTCase family
JNE45_RS07545	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JNE45_RS07550	COG0505	Belongs to the CarA family
JNE45_RS07555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JNE45_RS07560	COG0543	2 iron, 2 sulfur cluster binding
JNE45_RS07565	COG0167	dihydroorotate dehydrogenase activity
JNE45_RS07570	COG0284	orotidine-5'-phosphate decarboxylase activity
JNE45_RS07575	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JNE45_RS07585	COG0175	sulfate reduction
JNE45_RS07590	COG0306	phosphate transporter
JNE45_RS07595	COG2046	Belongs to the sulfate adenylyltransferase family
JNE45_RS07600	COG0529	Catalyzes the synthesis of activated sulfate
JNE45_RS07605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JNE45_RS07610	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JNE45_RS07615	COG1648	precorrin-2 dehydrogenase activity
JNE45_RS07630	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JNE45_RS07635	COG1561	YicC-like family, N-terminal region
JNE45_RS07640	COG2052	Domain of unknown function (DUF370)
JNE45_RS07645	COG0194	GDP metabolic process
JNE45_RS07650	COG1758	RNA polymerase activity
JNE45_RS07655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JNE45_RS07660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JNE45_RS07665	COG0242	peptide deformylase activity
JNE45_RS07670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JNE45_RS07675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JNE45_RS07675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JNE45_RS07680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JNE45_RS07685	COG0631	protein serine/threonine phosphatase activity
JNE45_RS07690	COG2815	serine threonine protein kinase
JNE45_RS07690	COG0515	serine threonine protein kinase
JNE45_RS07695	COG1162	GTPase activity
JNE45_RS07700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JNE45_RS07705	COG1564	THIamine pyrophosphokinase
JNE45_RS07715	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JNE45_RS07720	COG1302	Protein conserved in bacteria
JNE45_RS07725	COG1461	Dihydroxyacetone kinase
JNE45_RS07730	COG1760	l-serine dehydratase
JNE45_RS07735	COG1760	l-serine dehydratase
JNE45_RS07740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JNE45_RS07745	COG1349	DNA-binding transcription factor activity
JNE45_RS07750	COG0416	fatty acid biosynthetic process
JNE45_RS07755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JNE45_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS07765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNE45_RS07775	COG1196	nuclear chromosome segregation
JNE45_RS07780	COG0552	protein localization to endoplasmic reticulum
JNE45_RS07785	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JNE45_RS07790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JNE45_RS07795	COG0228	four-way junction DNA binding
JNE45_RS07800	COG1837	Belongs to the UPF0109 family
JNE45_RS07810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JNE45_RS07815	COG0336	Belongs to the RNA methyltransferase TrmD family
JNE45_RS07820	COG0335	large ribosomal subunit rRNA binding
JNE45_RS07825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JNE45_RS07830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNE45_RS07840	COG2257	FlhB HrpN YscU SpaS Family
JNE45_RS07845	COG0045	succinate-CoA ligase (ADP-forming) activity
JNE45_RS07850	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JNE45_RS07855	COG0758	DNA mediated transformation
JNE45_RS07860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JNE45_RS07865	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JNE45_RS07870	COG4974	Belongs to the 'phage' integrase family
JNE45_RS07875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JNE45_RS07880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JNE45_RS07885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JNE45_RS07890	COG1815	bacterial-type flagellum-dependent cell motility
JNE45_RS07895	COG1558	bacterial-type flagellum-dependent cell motility
JNE45_RS07900	COG1677	Flagellar hook-basal body complex protein FliE
JNE45_RS07905	COG1766	The M ring may be actively involved in energy transduction
JNE45_RS07910	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE45_RS07915	COG1317	bacterial-type flagellum organization
JNE45_RS07920	COG1157	protein secretion by the type III secretion system
JNE45_RS07925	COG2882	bacterial-type flagellum organization
JNE45_RS07930	COG3334	PFAM MgtE intracellular
JNE45_RS07935	COG3144	bacterial-type flagellum assembly
JNE45_RS07940	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JNE45_RS07945	COG4786	Flagellar basal body rod
JNE45_RS07950	COG1582	Flagellar protein (FlbD)
JNE45_RS07955	COG1580	Controls the rotational direction of flagella during chemotaxis
JNE45_RS07960	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE45_RS07965	COG1776	CheC inhibitor of MCP methylation
JNE45_RS07965	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JNE45_RS07970	COG2201	protein-glutamate methylesterase activity
JNE45_RS07975	COG3190	flagellar
JNE45_RS07980	COG1338	Plays a role in the flagellum-specific transport system
JNE45_RS07985	COG1987	bacterial-type flagellum assembly
JNE45_RS07990	COG1684	flagellar biosynthetic protein fliR
JNE45_RS07995	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JNE45_RS08000	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JNE45_RS08005	COG1419	protein localization to endoplasmic reticulum
JNE45_RS08010	COG0455	bacterial-type flagellum organization
JNE45_RS08015	COG2201	protein-glutamate methylesterase activity
JNE45_RS08020	COG0643	Histidine kinase
JNE45_RS08020	COG2198	Histidine kinase
JNE45_RS08025	COG0835	chemotaxis
JNE45_RS08030	COG1776	CheC inhibitor of MCP methylation
JNE45_RS08035	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JNE45_RS08040	COG1191	sigma factor activity
JNE45_RS08055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JNE45_RS08060	COG0528	UMP kinase activity
JNE45_RS08065	COG0233	cytoplasmic translational termination
JNE45_RS08070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JNE45_RS08075	COG4589	Belongs to the CDS family
JNE45_RS08080	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JNE45_RS08085	COG0750	zinc metalloprotease
JNE45_RS08090	COG0442	prolyl-tRNA aminoacylation
JNE45_RS08095	COG2176	DNA-directed DNA polymerase activity
JNE45_RS08110	COG3693	PFAM glycoside hydrolase, family 10
JNE45_RS08130	COG1131	(ABC) transporter
JNE45_RS08180	COG0779	Required for maturation of 30S ribosomal subunits
JNE45_RS08185	COG0195	Participates in both transcription termination and antitermination
JNE45_RS08190	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JNE45_RS08195	COG1358	cellular component organization or biogenesis
JNE45_RS08200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JNE45_RS08205	COG1550	Protein conserved in bacteria
JNE45_RS08210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JNE45_RS08215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JNE45_RS08220	COG0196	riboflavin kinase activity
JNE45_RS08225	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JNE45_RS08230	COG1185	polyribonucleotide nucleotidyltransferase activity
JNE45_RS08235	COG0726	polysaccharide deacetylase
JNE45_RS08240	COG0612	Peptidase, M16
JNE45_RS08250	COG1873	PFAM PRC-barrel domain
JNE45_RS08255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE45_RS08260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JNE45_RS08265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JNE45_RS08270	COG0527	aspartate kinase activity
JNE45_RS08280	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JNE45_RS08285	COG0740	serine-type endopeptidase activity
JNE45_RS08295	COG1674	ftsk spoiiie
JNE45_RS08295	COG4980	gas vesicle protein
JNE45_RS08300	COG2188	Transcriptional regulator
JNE45_RS08305	COG2814	Major facilitator Superfamily
JNE45_RS08310	COG2409	Drug exporters of the RND superfamily
JNE45_RS08310	COG1033	growth of symbiont in host cell
JNE45_RS08315	COG0612	Peptidase, M16
JNE45_RS08320	COG0612	Peptidase, M16
JNE45_RS08330	COG1033	growth of symbiont in host cell
JNE45_RS08330	COG2409	Drug exporters of the RND superfamily
JNE45_RS08335	COG0300	oxidoreductase activity
JNE45_RS08350	COG1426	Protein conserved in bacteria
JNE45_RS08355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JNE45_RS08360	COG1546	Belongs to the CinA family
JNE45_RS08360	COG1058	Belongs to the CinA family
JNE45_RS08365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JNE45_RS08370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JNE45_RS08375	COG1418	mRNA catabolic process
JNE45_RS08380	COG1692	metallophosphoesterase
JNE45_RS08385	COG2359	stage V sporulation protein S
JNE45_RS08390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JNE45_RS08395	COG1063	alcohol dehydrogenase
JNE45_RS08400	COG0156	8-amino-7-oxononanoate synthase activity
JNE45_RS08405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JNE45_RS08410	COG4550	Control of competence regulator ComK, YlbF/YmcA
JNE45_RS08420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JNE45_RS08425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JNE45_RS08440	COG1329	Transcriptional regulator
JNE45_RS08445	COG4195	phage-related replication protein
JNE45_RS08450	COG0457	Tetratricopeptide repeat
JNE45_RS08455	COG1404	Belongs to the peptidase S8 family
JNE45_RS08460	COG4195	phage-related replication protein
JNE45_RS08465	COG1764	response to oxidative stress
JNE45_RS08470	COG2076	Multidrug Resistance protein
JNE45_RS08495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JNE45_RS08500	COG1923	regulation of RNA biosynthetic process
JNE45_RS08515	COG1780	Probably involved in ribonucleotide reductase function
JNE45_RS08520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNE45_RS08525	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JNE45_RS08530	COG4112	unkown
JNE45_RS08535	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS08540	COG0464	growth
JNE45_RS08545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JNE45_RS08550	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JNE45_RS08555	COG0789	Transcriptional regulator
JNE45_RS08560	COG0174	glutamine synthetase
JNE45_RS08615	COG5484	DNA packaging
JNE45_RS08625	COG5518	Phage portal protein
JNE45_RS08630	COG2369	cell adhesion
JNE45_RS08650	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JNE45_RS08665	COG0457	Tetratricopeptide repeat
JNE45_RS08670	COG5444	nuclease activity
JNE45_RS08695	COG5646	InterPro IPR014922
JNE45_RS08700	COG0457	Tetratricopeptide repeat
JNE45_RS08710	COG3619	membrane
JNE45_RS08715	COG3285	dna ligase
JNE45_RS08715	COG1793	dna ligase
JNE45_RS08720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JNE45_RS08725	COG4876	unkown
JNE45_RS08730	COG0346	lactoylglutathione lyase activity
JNE45_RS08735	COG1959	2 iron, 2 sulfur cluster binding
JNE45_RS08740	COG0702	epimerase
JNE45_RS08745	COG0247	lactate metabolic process
JNE45_RS08750	COG1139	Iron-sulfur cluster binding protein
JNE45_RS08755	COG1556	Lactate utilization protein
JNE45_RS08775	COG2323	membrane
JNE45_RS08780	COG1309	transcriptional regulator
JNE45_RS08785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JNE45_RS08785	COG2124	cytochrome p450
JNE45_RS08790	COG3591	Belongs to the peptidase S1B family
JNE45_RS08795	COG3209	COG3209 Rhs family protein
JNE45_RS08800	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS08815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JNE45_RS08820	COG1388	LysM domain
JNE45_RS08825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JNE45_RS08830	COG4224	UPF0291 protein
JNE45_RS08835	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JNE45_RS08845	COG3763	UPF0154 protein
JNE45_RS08855	COG0785	Cytochrome C biogenesis protein
JNE45_RS08860	COG4846	Membrane protein involved in cytochrome C biogenesis
JNE45_RS08870	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE45_RS08885	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JNE45_RS08890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS08910	COG0824	Thioesterase
JNE45_RS08920	COG4841	protein insertion into membrane
JNE45_RS08925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JNE45_RS08930	COG1832	CoA-binding protein
JNE45_RS08935	COG0187	DNA topoisomerase II activity
JNE45_RS08940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JNE45_RS08950	COG0738	Major facilitator superfamily
JNE45_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS08965	COG1312	Catalyzes the dehydration of D-mannonate
JNE45_RS08970	COG1802	Transcriptional regulator
JNE45_RS08975	COG0673	inositol 2-dehydrogenase activity
JNE45_RS08985	COG1904	glucuronate isomerase
JNE45_RS08990	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE45_RS08995	COG1733	regulation of RNA biosynthetic process
JNE45_RS09005	COG2197	response regulator
JNE45_RS09010	COG4585	Histidine kinase
JNE45_RS09015	COG2409	Drug exporters of the RND superfamily
JNE45_RS09020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE45_RS09025	COG0251	oxidation-reduction process
JNE45_RS09065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JNE45_RS09080	COG0583	DNA-binding transcription factor activity
JNE45_RS09105	COG0657	acetylesterase activity
JNE45_RS09110	COG0789	Transcriptional regulator
JNE45_RS09120	COG2205	protein histidine kinase activity
JNE45_RS09125	COG0745	RESPONSE REGULATOR receiver
JNE45_RS09135	COG3507	Belongs to the glycosyl hydrolase 43 family
JNE45_RS09140	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS09145	COG1486	melibiose metabolic process
JNE45_RS09150	COG0395	ABC-type sugar transport system, permease component
JNE45_RS09155	COG1175	transmembrane transport
JNE45_RS09160	COG1653	transport
JNE45_RS09165	COG1609	Transcriptional regulator
JNE45_RS09170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JNE45_RS09185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS09195	COG0456	acetyltransferase
JNE45_RS09200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS09235	COG5444	nuclease activity
JNE45_RS09250	COG1846	Transcriptional regulator
JNE45_RS09255	COG2814	Major facilitator Superfamily
JNE45_RS09265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS09265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS09265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS09270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS09270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JNE45_RS09270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS09275	COG1105	Belongs to the carbohydrate kinase PfkB family
JNE45_RS09285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE45_RS09315	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JNE45_RS09320	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE45_RS09325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE45_RS09330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JNE45_RS09335	COG1024	Enoyl-CoA hydratase
JNE45_RS09340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE45_RS09345	COG0511	ligase activity, forming carbon-carbon bonds
JNE45_RS09350	COG0439	Biotin carboxylase
JNE45_RS09355	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS09360	COG1960	acyl-CoA dehydrogenase activity
JNE45_RS09365	COG1649	PFAM Uncharacterised BCR, COG1649
JNE45_RS09370	COG2365	Tyrosine phosphatase family
JNE45_RS09375	COG1349	DNA-binding transcription factor activity
JNE45_RS09385	COG3835	regulator
JNE45_RS09390	COG0277	FAD linked oxidase domain protein
JNE45_RS09395	COG0247	lactate metabolic process
JNE45_RS09420	COG0166	Belongs to the GPI family
JNE45_RS09425	COG2246	polysaccharide biosynthetic process
JNE45_RS09430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JNE45_RS09435	COG0586	Pfam SNARE associated Golgi protein
JNE45_RS09440	COG1587	Uroporphyrinogen-III synthase
JNE45_RS09450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS09465	COG0534	Mate efflux family protein
JNE45_RS09470	COG2027	D-alanyl-D-alanine carboxypeptidase
JNE45_RS09475	COG4677	pectinesterase activity
JNE45_RS09480	COG2323	membrane
JNE45_RS09485	COG2146	nitrite reductase [NAD(P)H] activity
JNE45_RS09490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE45_RS09495	COG0243	molybdopterin cofactor binding
JNE45_RS09500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JNE45_RS09505	COG2223	nitrite transmembrane transporter activity
JNE45_RS09510	COG0493	'glutamate synthase
JNE45_RS09515	COG0070	glutamate synthase
JNE45_RS09515	COG0067	glutamate synthase
JNE45_RS09515	COG0069	glutamate synthase activity
JNE45_RS09520	COG0583	DNA-binding transcription factor activity
JNE45_RS09530	COG1132	(ABC) transporter
JNE45_RS09535	COG4978	Transcriptional regulator
JNE45_RS09535	COG0789	Transcriptional regulator
JNE45_RS09540	COG0454	-acetyltransferase
JNE45_RS09545	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JNE45_RS09550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JNE45_RS09565	COG0243	molybdopterin cofactor binding
JNE45_RS09575	COG1070	Carbohydrate kinase
JNE45_RS09580	COG2115	Belongs to the xylose isomerase family
JNE45_RS09585	COG1940	carbohydrate kinase activity
JNE45_RS09595	COG2211	Major facilitator Superfamily
JNE45_RS09600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE45_RS09605	COG1994	Peptidase M50
JNE45_RS09625	COG1309	transcriptional regulator
JNE45_RS09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE45_RS09635	COG3708	Transcriptional regulator
JNE45_RS09640	COG2378	regulation of single-species biofilm formation
JNE45_RS09650	COG0640	Transcriptional regulator
JNE45_RS09655	COG0531	amino acid
JNE45_RS09660	COG0741	lytic transglycosylase activity
JNE45_RS09670	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JNE45_RS09675	COG2079	MmgE PrpD family protein
JNE45_RS09680	COG0372	Belongs to the citrate synthase family
JNE45_RS09685	COG2322	membrane
JNE45_RS09695	COG3584	3D domain protein
JNE45_RS09695	COG1388	LysM domain
JNE45_RS09700	COG0514	ATP-dependent DNA helicase (RecQ)
JNE45_RS09710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE45_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS09745	COG1657	PFAM Prenyltransferase squalene oxidase
JNE45_RS09750	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JNE45_RS09755	COG0385	Bile acid
JNE45_RS09760	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS09765	COG0567	Dehydrogenase, E1 component
JNE45_RS09770	COG4548	von Willebrand factor, type A
JNE45_RS09775	COG0714	Associated with various cellular activities
JNE45_RS09780	COG2032	superoxide dismutase activity
JNE45_RS09785	COG1388	LysM domain
JNE45_RS09785	COG0791	NLP P60 protein
JNE45_RS09790	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JNE45_RS09795	COG0534	Mate efflux family protein
JNE45_RS09800	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE45_RS09805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE45_RS09815	COG2962	Rard protein
JNE45_RS09830	COG1733	regulation of RNA biosynthetic process
JNE45_RS09835	COG0778	Nitroreductase
JNE45_RS09845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE45_RS09850	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JNE45_RS09855	COG3409	Peptidoglycan-binding domain 1 protein
JNE45_RS09855	COG0793	Belongs to the peptidase S41A family
JNE45_RS09860	COG2226	methyltransferase
JNE45_RS09870	COG1876	peptidase activity
JNE45_RS09875	COG0813	purine-nucleoside phosphorylase activity
JNE45_RS09885	COG0671	phosphoesterase, PA-phosphatase related
JNE45_RS09900	COG4479	Belongs to the UPF0346 family
JNE45_RS09910	COG1509	lysine 2,3-aminomutase activity
JNE45_RS09915	COG3829	transcription factor binding
JNE45_RS09920	COG0463	Glycosyl transferase, family 2
JNE45_RS09935	COG4641	Protein conserved in bacteria
JNE45_RS09945	COG1086	Polysaccharide biosynthesis protein
JNE45_RS09950	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JNE45_RS09955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JNE45_RS09960	COG1846	Transcriptional regulator
JNE45_RS09980	COG4698	Protein conserved in bacteria
JNE45_RS09985	COG2755	lipolytic protein G-D-S-L family
JNE45_RS09990	COG1999	signal sequence binding
JNE45_RS10005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JNE45_RS10010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JNE45_RS10015	COG1272	protein, Hemolysin III
JNE45_RS10020	COG0204	Acyl-transferase
JNE45_RS10025	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JNE45_RS10030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JNE45_RS10035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JNE45_RS10045	COG2136	Putative SAM-dependent methyltransferase
JNE45_RS10045	COG2521	methyltransferase
JNE45_RS10055	COG0129	dihydroxy-acid dehydratase activity
JNE45_RS10060	COG1413	lyase activity
JNE45_RS10065	COG1418	mRNA catabolic process
JNE45_RS10070	COG0386	Belongs to the glutathione peroxidase family
JNE45_RS10075	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JNE45_RS10080	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JNE45_RS10085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JNE45_RS10095	COG1278	Cold shock
JNE45_RS10110	COG0328	RNA-DNA hybrid ribonuclease activity
JNE45_RS10115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JNE45_RS10120	COG0328	RNA-DNA hybrid ribonuclease activity
JNE45_RS10130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE45_RS10140	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JNE45_RS10150	COG1755	Isoprenylcysteine carboxyl methyltransferase
JNE45_RS10155	COG3424	synthase
JNE45_RS10160	COG0726	polysaccharide deacetylase
JNE45_RS10165	COG2233	PERMEase
JNE45_RS10170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE45_RS10175	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JNE45_RS10180	COG1199	ATP-dependent helicase activity
JNE45_RS10190	COG0116	Belongs to the methyltransferase superfamily
JNE45_RS10200	COG3599	regulation of cell shape
JNE45_RS10205	COG4474	Belongs to the UPF0398 family
JNE45_RS10215	COG3359	exonuclease
JNE45_RS10220	COG1205	dead DEAH box helicase
JNE45_RS10220	COG1111	helicase
JNE45_RS10225	COG1902	pentaerythritol trinitrate reductase activity
JNE45_RS10230	COG2190	(PTS) system
JNE45_RS10235	COG0071	Belongs to the small heat shock protein (HSP20) family
JNE45_RS10265	COG3331	DNA recombination
JNE45_RS10270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE45_RS10270	COG4499	WXG100 protein secretion system (Wss), protein YukC
JNE45_RS10280	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JNE45_RS10285	COG3935	DnaD domain protein
JNE45_RS10290	COG0017	Asparaginyl-tRNA synthetase
JNE45_RS10295	COG5353	protein conserved in bacteria
JNE45_RS10305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JNE45_RS10305	COG1199	ATP-dependent helicase activity
JNE45_RS10310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JNE45_RS10315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JNE45_RS10320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JNE45_RS10330	COG0617	tRNA 3'-terminal CCA addition
JNE45_RS10335	COG0438	transferase activity, transferring glycosyl groups
JNE45_RS10340	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JNE45_RS10345	COG1803	Methylglyoxal synthase
JNE45_RS10350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JNE45_RS10355	COG1694	Mazg nucleotide pyrophosphohydrolase
JNE45_RS10360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE45_RS10370	COG4347	Protein of unknown function (DUF1405)
JNE45_RS10375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JNE45_RS10375	COG2010	Cytochrome c
JNE45_RS10380	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JNE45_RS10385	COG0723	plastoquinol--plastocyanin reductase activity
JNE45_RS10395	COG5582	Belongs to the UPF0302 family
JNE45_RS10400	COG0457	Tetratricopeptide repeat
JNE45_RS10405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JNE45_RS10410	COG0287	Prephenate dehydrogenase
JNE45_RS10415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JNE45_RS10420	COG0159	tryptophan synthase activity
JNE45_RS10425	COG0133	tryptophan synthase activity
JNE45_RS10430	COG0135	phosphoribosylanthranilate isomerase activity
JNE45_RS10435	COG0134	indole-3-glycerol-phosphate synthase activity
JNE45_RS10450	COG4401	Chorismate mutase type I
JNE45_RS10455	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JNE45_RS10460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JNE45_RS10465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JNE45_RS10470	COG0105	UTP biosynthetic process
JNE45_RS10475	COG0142	geranyltranstransferase activity
JNE45_RS10480	COG2226	methyltransferase
JNE45_RS10485	COG0142	geranyltranstransferase activity
JNE45_RS10495	COG0302	gtp cyclohydrolase
JNE45_RS10500	COG0776	regulation of translation
JNE45_RS10505	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JNE45_RS10520	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JNE45_RS10525	COG1160	GTP binding
JNE45_RS10550	COG1304	FMN binding
JNE45_RS10555	COG0539	negative regulation of cytoplasmic translation
JNE45_RS10560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JNE45_RS10570	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JNE45_RS10575	COG2959	enzyme of heme biosynthesis
JNE45_RS10580	COG3409	Peptidoglycan-binding domain 1 protein
JNE45_RS10580	COG3773	Cell wall hydrolase
JNE45_RS10585	COG2339	peptidase activity
JNE45_RS10590	COG0492	ferredoxin-NADP+ reductase activity
JNE45_RS10595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE45_RS10600	COG4862	establishment of competence for transformation
JNE45_RS10605	COG1408	metallophosphoesterase
JNE45_RS10615	COG1388	LysM domain
JNE45_RS10620	COG1266	CAAX protease self-immunity
JNE45_RS10625	COG0514	ATP-dependent DNA helicase (RecQ)
JNE45_RS10630	COG4955	Helix-turn-helix domain
JNE45_RS10635	COG1141	Ferredoxin
JNE45_RS10640	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JNE45_RS10645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JNE45_RS10650	COG1388	LysM domain
JNE45_RS10650	COG0791	NLP P60 protein
JNE45_RS10660	COG1595	DNA-templated transcription, initiation
JNE45_RS10665	COG5002	protein histidine kinase activity
JNE45_RS10670	COG0745	RESPONSE REGULATOR receiver
JNE45_RS10675	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JNE45_RS10680	COG1333	cytochrome c biogenesis protein
JNE45_RS10685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS10690	COG1187	pseudouridine synthase activity
JNE45_RS10695	COG0700	Nucleoside recognition
JNE45_RS10700	COG2715	membrane protein required for spore maturation
JNE45_RS10705	COG1686	Belongs to the peptidase S11 family
JNE45_RS10715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JNE45_RS10720	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JNE45_RS10730	COG1547	Domain of unknown function (DUF309)
JNE45_RS10735	COG0456	acetyltransferase
JNE45_RS10740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JNE45_RS10745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS10745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS10750	COG0307	riboflavin synthase, alpha
JNE45_RS10770	COG2814	Major facilitator Superfamily
JNE45_RS10775	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JNE45_RS10780	COG4086	secreted protein
JNE45_RS10785	COG0019	diaminopimelate decarboxylase activity
JNE45_RS10790	COG0697	spore germination
JNE45_RS10805	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JNE45_RS10825	COG1191	sigma factor activity
JNE45_RS10830	COG2172	sigma factor antagonist activity
JNE45_RS10840	COG1686	Belongs to the peptidase S11 family
JNE45_RS10845	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JNE45_RS10850	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JNE45_RS10855	COG4974	Belongs to the 'phage' integrase family
JNE45_RS10865	COG0735	belongs to the Fur family
JNE45_RS10870	COG1300	Membrane
JNE45_RS10875	COG1404	Belongs to the peptidase S8 family
JNE45_RS10885	COG2153	protein acetylation
JNE45_RS10890	COG1379	DNA repair
JNE45_RS10895	COG0494	nUDIX hydrolase
JNE45_RS10900	COG0667	Aldo Keto reductase
JNE45_RS10910	COG1073	alpha beta
JNE45_RS10915	COG0457	Tetratricopeptide repeat
JNE45_RS10925	COG4918	Iron-sulphur cluster biosynthesis
JNE45_RS10930	COG0456	acetyltransferase
JNE45_RS10930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JNE45_RS10935	COG0456	acetyltransferase
JNE45_RS10945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JNE45_RS10955	COG2211	Major facilitator Superfamily
JNE45_RS10960	COG1072	(Pantothenic acid kinase))
JNE45_RS10965	COG0446	pyridine nucleotide-disulphide oxidoreductase
JNE45_RS10970	COG0300	oxidoreductase activity
JNE45_RS10975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE45_RS10980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE45_RS10990	COG4187	Peptidase family M20/M25/M40
JNE45_RS10995	COG1902	pentaerythritol trinitrate reductase activity
JNE45_RS11000	COG0596	Alpha beta hydrolase
JNE45_RS11005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JNE45_RS11015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JNE45_RS11020	COG2188	Transcriptional regulator
JNE45_RS11025	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS11030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS11035	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE45_RS11040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS11045	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS11055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JNE45_RS11060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JNE45_RS11075	COG0706	membrane insertase activity
JNE45_RS11085	COG2195	Cleaves the N-terminal amino acid of tripeptides
JNE45_RS11090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JNE45_RS11095	COG0346	lactoylglutathione lyase activity
JNE45_RS11105	COG1376	ErfK ybiS ycfS ynhG family protein
JNE45_RS11110	COG4129	membrane
JNE45_RS11115	COG1126	abc transporter atp-binding protein
JNE45_RS11120	COG0765	amino acid transport
JNE45_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS11135	COG1597	lipid kinase activity
JNE45_RS11145	COG0508	dehydrogenase complex catalyzes the overall conversion of
JNE45_RS11150	COG0022	dehydrogenase e1 component
JNE45_RS11155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JNE45_RS11160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JNE45_RS11165	COG3426	butyrate kinase activity
JNE45_RS11170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE45_RS11175	COG0280	phosphate acetyltransferase
JNE45_RS11180	COG3829	transcription factor binding
JNE45_RS11180	COG3290	protein histidine kinase activity
JNE45_RS11190	COG0584	glycerophosphoryl diester phosphodiesterase
JNE45_RS11195	COG0457	Tetratricopeptide repeat
JNE45_RS11200	COG0745	RESPONSE REGULATOR receiver
JNE45_RS11205	COG0750	zinc metalloprotease
JNE45_RS11210	COG0497	DNA recombination
JNE45_RS11215	COG1438	arginine binding
JNE45_RS11220	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JNE45_RS11225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JNE45_RS11230	COG0142	geranyltranstransferase activity
JNE45_RS11235	COG1722	exodeoxyribonuclease VII activity
JNE45_RS11240	COG1570	exodeoxyribonuclease VII activity
JNE45_RS11245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JNE45_RS11250	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JNE45_RS11255	COG1302	Protein conserved in bacteria
JNE45_RS11260	COG0439	Biotin carboxylase
JNE45_RS11265	COG0511	ligase activity, forming carbon-carbon bonds
JNE45_RS11305	COG3854	ATPases associated with a variety of cellular activities
JNE45_RS11315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JNE45_RS11320	COG0006	proline dipeptidase activity
JNE45_RS11325	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JNE45_RS11335	COG3872	metal-dependent enzyme
JNE45_RS11345	COG1752	Esterase of the alpha-beta hydrolase superfamily
JNE45_RS11350	COG1321	iron dependent repressor
JNE45_RS11355	COG0095	Lipoate-protein ligase
JNE45_RS11360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE45_RS11365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JNE45_RS11370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JNE45_RS11375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JNE45_RS11380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JNE45_RS11405	COG0681	Belongs to the peptidase S26 family
JNE45_RS11435	COG4970	Tfp pilus assembly protein FimT
JNE45_RS11440	COG4537	Required for transformation and DNA binding
JNE45_RS11445	COG1459	type II secretion system
JNE45_RS11450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JNE45_RS11455	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS11465	COG1393	Belongs to the ArsC family
JNE45_RS11475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE45_RS11485	COG0011	TIGRFAM Protein of
JNE45_RS11490	COG2814	Major facilitator Superfamily
JNE45_RS11495	COG2866	Carboxypeptidase
JNE45_RS11500	COG1368	sulfuric ester hydrolase activity
JNE45_RS11505	COG1940	carbohydrate kinase activity
JNE45_RS11510	COG4483	Protein conserved in bacteria
JNE45_RS11515	COG0457	Tetratricopeptide repeat
JNE45_RS11515	COG0705	Rhomboid family
JNE45_RS11525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JNE45_RS11530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE45_RS11540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JNE45_RS11545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JNE45_RS11550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JNE45_RS11555	COG0581	inorganic phosphate transmembrane transporter activity
JNE45_RS11560	COG0573	inorganic phosphate transmembrane transporter activity
JNE45_RS11565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JNE45_RS11570	COG0768	penicillin binding
JNE45_RS11575	COG0477	Major facilitator Superfamily
JNE45_RS11580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JNE45_RS11585	COG2839	Protein conserved in bacteria
JNE45_RS11590	COG5521	maltodextrose utilization protein MalA
JNE45_RS11595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JNE45_RS11600	COG1388	LysM domain
JNE45_RS11605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JNE45_RS11610	COG4709	membrane
JNE45_RS11615	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JNE45_RS11620	COG1940	carbohydrate kinase activity
JNE45_RS11630	COG0735	belongs to the Fur family
JNE45_RS11635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JNE45_RS11640	COG1121	(ABC) transporter
JNE45_RS11645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE45_RS11655	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JNE45_RS11660	COG0513	Belongs to the DEAD box helicase family
JNE45_RS11670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JNE45_RS11675	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JNE45_RS11680	COG2384	SAM-dependent methyltransferase
JNE45_RS11685	COG2010	Cytochrome c
JNE45_RS11690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JNE45_RS11695	COG0358	DNA primase activity
JNE45_RS11700	COG1671	Belongs to the UPF0178 family
JNE45_RS11705	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JNE45_RS11710	COG0517	IMP dehydrogenase activity
JNE45_RS11715	COG0751	glycine-tRNA ligase activity
JNE45_RS11720	COG0752	glycyl-tRNA synthetase alpha subunit
JNE45_RS11725	COG1381	Involved in DNA repair and RecF pathway recombination
JNE45_RS11735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JNE45_RS11740	COG0295	cytidine deaminase activity
JNE45_RS11745	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JNE45_RS11750	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JNE45_RS11755	COG1480	7TM receptor with intracellular HD hydrolase
JNE45_RS11760	COG1702	phosphate starvation-inducible protein PhoH
JNE45_RS11765	COG0561	phosphatase activity
JNE45_RS11780	COG4864	UPF0365 protein
JNE45_RS11785	COG1030	water channel activity
JNE45_RS11790	COG1610	YqeY-like protein
JNE45_RS11800	COG1283	sodium-dependent phosphate transmembrane transporter activity
JNE45_RS11805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JNE45_RS11810	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JNE45_RS11815	COG2264	protein methyltransferase activity
JNE45_RS11820	COG0484	heat shock protein binding
JNE45_RS11825	COG0443	Heat shock 70 kDa protein
JNE45_RS11830	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JNE45_RS11835	COG1420	regulation of RNA biosynthetic process
JNE45_RS11840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JNE45_RS11845	COG0481	GTPase activity
JNE45_RS11855	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS11860	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JNE45_RS11865	COG0268	Binds directly to 16S ribosomal RNA
JNE45_RS11870	COG1466	dna polymerase III delta subunit
JNE45_RS11880	COG2333	competence protein COMEC
JNE45_RS11880	COG0658	competence protein
JNE45_RS11885	COG2131	deaminase
JNE45_RS11890	COG1555	photosystem II stabilization
JNE45_RS11895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JNE45_RS11900	COG2226	methyltransferase
JNE45_RS11905	COG0799	negative regulation of ribosome biogenesis
JNE45_RS11910	COG1713	HD superfamily hydrolase involved in NAD metabolism
JNE45_RS11915	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JNE45_RS11920	COG1534	Rna-binding protein
JNE45_RS11925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JNE45_RS11930	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JNE45_RS11935	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JNE45_RS11950	COG2755	lipolytic protein G-D-S-L family
JNE45_RS11960	COG0457	Tetratricopeptide repeat
JNE45_RS11970	COG2318	DinB family
JNE45_RS12000	COG0726	polysaccharide deacetylase
JNE45_RS12035	COG1122	ATPase activity
JNE45_RS12055	COG2160	L-arabinose isomerase activity
JNE45_RS12070	COG1609	Transcriptional regulator
JNE45_RS12080	COG1846	Transcriptional regulator
JNE45_RS12110	COG0657	acetylesterase activity
JNE45_RS12130	COG2602	Beta-lactamase
JNE45_RS12135	COG1960	acyl-CoA dehydrogenase activity
JNE45_RS12140	COG1126	abc transporter atp-binding protein
JNE45_RS12145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS12150	COG0765	amino acid transport
JNE45_RS12160	COG3546	catalase activity
JNE45_RS12165	COG1063	alcohol dehydrogenase
JNE45_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS12185	COG1115	amino acid carrier protein
JNE45_RS12190	COG0583	DNA-binding transcription factor activity
JNE45_RS12200	COG2226	methyltransferase
JNE45_RS12205	COG1063	alcohol dehydrogenase
JNE45_RS12210	COG2226	methyltransferase
JNE45_RS12235	COG0626	cystathionine gamma-synthase activity
JNE45_RS12240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE45_RS12245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JNE45_RS12250	COG2226	methyltransferase
JNE45_RS12265	COG0768	penicillin binding
JNE45_RS12270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JNE45_RS12280	COG0572	uridine kinase
JNE45_RS12285	COG0826	peptidase U32
JNE45_RS12290	COG0826	peptidase U32
JNE45_RS12295	COG4122	O-methyltransferase activity
JNE45_RS12300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JNE45_RS12305	COG0183	Belongs to the thiolase family
JNE45_RS12310	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS12315	COG1268	BioY protein
JNE45_RS12320	COG3906	Belongs to the UPF0473 family
JNE45_RS12325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JNE45_RS12330	COG4472	Bacterial protein of unknown function (DUF965)
JNE45_RS12335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JNE45_RS12340	COG0628	permease
JNE45_RS12345	COG1126	abc transporter atp-binding protein
JNE45_RS12350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS12355	COG0765	amino acid transport
JNE45_RS12360	COG0765	amino acid transport
JNE45_RS12375	COG3881	PFAM PRC-barrel domain
JNE45_RS12380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JNE45_RS12385	COG0457	Tetratricopeptide repeat
JNE45_RS12390	COG0482	sulfurtransferase activity
JNE45_RS12395	COG1104	cysteine desulfurase activity
JNE45_RS12400	COG1959	2 iron, 2 sulfur cluster binding
JNE45_RS12405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JNE45_RS12410	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JNE45_RS12425	COG0124	histidyl-tRNA synthetase
JNE45_RS12435	COG4991	sh3 domain protein
JNE45_RS12435	COG3103	Sh3 type 3 domain protein
JNE45_RS12435	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS12440	COG1490	D-aminoacyl-tRNA deacylase activity
JNE45_RS12445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JNE45_RS12450	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JNE45_RS12455	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JNE45_RS12455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JNE45_RS12460	COG5416	Lipopolysaccharide assembly protein A domain
JNE45_RS12465	COG0490	domain, Protein
JNE45_RS12470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JNE45_RS12470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JNE45_RS12480	COG2244	polysaccharide biosynthetic process
JNE45_RS12485	COG2323	membrane
JNE45_RS12495	COG1862	Preprotein translocase
JNE45_RS12500	COG0343	queuine tRNA-ribosyltransferase activity
JNE45_RS12505	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JNE45_RS12515	COG2255	four-way junction helicase activity
JNE45_RS12520	COG0632	four-way junction helicase activity
JNE45_RS12530	COG2112	serine threonine protein kinase
JNE45_RS12545	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JNE45_RS12560	COG1388	LysM domain
JNE45_RS12560	COG1388	LysM domain
JNE45_RS12565	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JNE45_RS12570	COG0157	Belongs to the NadC ModD family
JNE45_RS12575	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JNE45_RS12580	COG1104	cysteine desulfurase activity
JNE45_RS12585	COG1827	regulation of RNA biosynthetic process
JNE45_RS12590	COG0077	Prephenate dehydratase
JNE45_RS12595	COG4492	Belongs to the UPF0735 family
JNE45_RS12600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JNE45_RS12605	COG3290	protein histidine kinase activity
JNE45_RS12610	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JNE45_RS12615	COG2868	ribosomal protein
JNE45_RS12620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JNE45_RS12625	COG1994	Peptidase M50
JNE45_RS12630	COG0739	heme binding
JNE45_RS12635	COG2894	cell division
JNE45_RS12640	COG0850	regulation of cytokinetic process
JNE45_RS12645	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JNE45_RS12655	COG1077	Cell shape determining protein MreB Mrl
JNE45_RS12660	COG2003	Belongs to the UPF0758 family
JNE45_RS12665	COG0424	maF-like protein
JNE45_RS12675	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JNE45_RS12680	COG0285	dihydrofolate synthase activity
JNE45_RS12685	COG0525	valine-tRNA ligase activity
JNE45_RS12695	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE45_RS12700	COG1388	LysM domain
JNE45_RS12705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JNE45_RS12710	COG0113	porphobilinogen synthase activity
JNE45_RS12715	COG1587	Uroporphyrinogen-III synthase
JNE45_RS12720	COG0181	hydroxymethylbilane synthase activity
JNE45_RS12725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JNE45_RS12730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JNE45_RS12740	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JNE45_RS12745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JNE45_RS12750	COG0470	DNA polymerase III
JNE45_RS12750	COG1067	ATP-dependent peptidase activity
JNE45_RS12755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JNE45_RS12760	COG0544	peptidyl-prolyl cis-trans isomerase activity
JNE45_RS12765	COG1477	protein flavinylation
JNE45_RS12765	COG0457	Tetratricopeptide repeat
JNE45_RS12770	COG0066	3-isopropylmalate dehydratase activity
JNE45_RS12775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JNE45_RS12780	COG0473	3-isopropylmalate dehydrogenase activity
JNE45_RS12785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JNE45_RS12790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JNE45_RS12795	COG0440	acetolactate synthase activity
JNE45_RS12800	COG0028	Belongs to the TPP enzyme family
JNE45_RS12805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE45_RS12810	COG2706	6-phosphogluconolactonase activity
JNE45_RS12815	COG3339	Conserved Protein
JNE45_RS12820	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JNE45_RS12825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JNE45_RS12830	COG1696	Membrane protein involved in D-alanine export
JNE45_RS12845	COG0346	lactoylglutathione lyase activity
JNE45_RS12895	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JNE45_RS12905	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS12920	COG0622	Phosphoesterase
JNE45_RS12925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JNE45_RS12930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JNE45_RS12935	COG5401	PFAM Sporulation and spore germination
JNE45_RS12940	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JNE45_RS12945	COG1846	Transcriptional regulator
JNE45_RS12950	COG2197	response regulator
JNE45_RS12955	COG2851	Citrate transporter
JNE45_RS12960	COG0583	DNA-binding transcription factor activity
JNE45_RS12965	COG2828	Protein conserved in bacteria
JNE45_RS12975	COG0824	Thioesterase
JNE45_RS12980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JNE45_RS12985	COG1053	succinate dehydrogenase
JNE45_RS12990	COG2009	succinate dehydrogenase
JNE45_RS12995	COG1719	4-vinyl reductase, 4VR
JNE45_RS13000	COG0527	aspartate kinase activity
JNE45_RS13005	COG0322	excinuclease ABC activity
JNE45_RS13010	COG3118	belongs to the thioredoxin family
JNE45_RS13015	COG3534	alpha-L-arabinofuranosidase
JNE45_RS13020	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JNE45_RS13025	COG2086	electron transfer activity
JNE45_RS13030	COG1024	Enoyl-CoA hydratase
JNE45_RS13035	COG1309	transcriptional regulator
JNE45_RS13040	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS13050	COG3766	membrane
JNE45_RS13055	COG1193	negative regulation of DNA recombination
JNE45_RS13060	COG1796	DNA polymerase
JNE45_RS13060	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JNE45_RS13065	COG1286	toxin biosynthetic process
JNE45_RS13070	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JNE45_RS13075	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JNE45_RS13080	COG0072	phenylalanine-tRNA ligase activity
JNE45_RS13080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE45_RS13085	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JNE45_RS13090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JNE45_RS13100	COG1966	Carbon starvation protein
JNE45_RS13105	COG1363	Peptidase, m42
JNE45_RS13115	COG3326	Membrane
JNE45_RS13120	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JNE45_RS13125	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JNE45_RS13130	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JNE45_RS13135	COG1346	cytolysis
JNE45_RS13145	COG3279	Response regulator of the LytR AlgR family
JNE45_RS13150	COG3275	phosphorelay sensor kinase activity
JNE45_RS13155	COG1011	Hydrolase
JNE45_RS13165	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JNE45_RS13175	COG0398	Pfam SNARE associated Golgi protein
JNE45_RS13180	COG1484	DNA-dependent DNA replication
JNE45_RS13185	COG3611	Membrane attachment protein
JNE45_RS13190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JNE45_RS13200	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JNE45_RS13205	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JNE45_RS13210	COG0237	dephospho-CoA kinase activity
JNE45_RS13215	COG1971	Probably functions as a manganese efflux pump
JNE45_RS13220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JNE45_RS13225	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE45_RS13225	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JNE45_RS13230	COG5002	protein histidine kinase activity
JNE45_RS13235	COG0745	RESPONSE REGULATOR receiver
JNE45_RS13240	COG0039	L-malate dehydrogenase activity
JNE45_RS13245	COG0538	isocitrate dehydrogenase activity
JNE45_RS13250	COG0372	Belongs to the citrate synthase family
JNE45_RS13255	COG2707	UPF0756 membrane protein
JNE45_RS13260	COG0628	permease
JNE45_RS13265	COG3030	protein affecting phage T7 exclusion by the F plasmid
JNE45_RS13275	COG0205	6-phosphofructokinase activity
JNE45_RS13280	COG0825	malonyl-CoA metabolic process
JNE45_RS13285	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JNE45_RS13290	COG0281	malic enzyme
JNE45_RS13295	COG0587	DNA-directed DNA polymerase activity
JNE45_RS13315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JNE45_RS13325	COG4109	DRTGG domain
JNE45_RS13330	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JNE45_RS13335	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS13345	COG0165	Argininosuccinate lyase
JNE45_RS13350	COG0137	argininosuccinate synthase activity
JNE45_RS13355	COG0521	Mo-molybdopterin cofactor biosynthetic process
JNE45_RS13360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JNE45_RS13365	COG0827	DNA restriction-modification system
JNE45_RS13370	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JNE45_RS13375	COG3874	Sporulation protein YtfJ
JNE45_RS13385	COG1714	RDD family
JNE45_RS13390	COG0616	signal peptide processing
JNE45_RS13395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JNE45_RS13405	COG3239	Fatty acid desaturase
JNE45_RS13410	COG4585	Histidine kinase
JNE45_RS13415	COG2197	response regulator
JNE45_RS13420	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS13425	COG0745	RESPONSE REGULATOR receiver
JNE45_RS13430	COG0642	Histidine kinase
JNE45_RS13435	COG0772	Belongs to the SEDS family
JNE45_RS13440	COG1695	Transcriptional regulator
JNE45_RS13445	COG1136	(ABC) transporter
JNE45_RS13450	COG0577	efflux transmembrane transporter activity
JNE45_RS13455	COG0402	S-adenosylhomocysteine deaminase activity
JNE45_RS13460	COG2249	NAD(P)H dehydrogenase (quinone) activity
JNE45_RS13470	COG1279	arginine transmembrane transporter activity
JNE45_RS13475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE45_RS13485	COG0301	tRNA thio-modification
JNE45_RS13490	COG1104	cysteine desulfurase activity
JNE45_RS13495	COG1114	Component of the transport system for branched-chain amino acids
JNE45_RS13500	COG1114	Component of the transport system for branched-chain amino acids
JNE45_RS13505	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JNE45_RS13510	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JNE45_RS13515	COG1309	transcriptional regulator
JNE45_RS13520	COG1956	GAF domain-containing protein
JNE45_RS13525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JNE45_RS13535	COG1335	isochorismatase
JNE45_RS13545	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JNE45_RS13550	COG2329	Antibiotic biosynthesis monooxygenase
JNE45_RS13555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JNE45_RS13560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JNE45_RS13565	COG0454	-acetyltransferase
JNE45_RS13570	COG0517	IMP dehydrogenase activity
JNE45_RS13575	COG0123	including yeast histone deacetylase and acetoin utilization protein
JNE45_RS13580	COG1609	Transcriptional regulator
JNE45_RS13585	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JNE45_RS13585	COG1605	Chorismate mutase
JNE45_RS13590	COG3118	belongs to the thioredoxin family
JNE45_RS13595	COG4980	gas vesicle protein
JNE45_RS13600	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JNE45_RS13605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JNE45_RS13610	COG1674	ftsk spoiiie
JNE45_RS13615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JNE45_RS13620	COG4848	Belongs to the UPF0354 family
JNE45_RS13625	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS13640	COG1363	Peptidase, m42
JNE45_RS13645	COG5584	Small secreted protein
JNE45_RS13650	COG0281	malic enzyme
JNE45_RS13655	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JNE45_RS13660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JNE45_RS13670	COG0510	thiamine kinase activity
JNE45_RS13675	COG1597	lipid kinase activity
JNE45_RS13685	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JNE45_RS13690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JNE45_RS13695	COG3340	Belongs to the peptidase S51 family
JNE45_RS13700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JNE45_RS13705	COG2252	PERMEase
JNE45_RS13710	COG1349	DNA-binding transcription factor activity
JNE45_RS13715	COG1187	pseudouridine synthase activity
JNE45_RS13720	COG2244	polysaccharide biosynthetic process
JNE45_RS13725	COG2081	HI0933 family
JNE45_RS13735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JNE45_RS13740	COG3196	Protein conserved in bacteria
JNE45_RS13750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JNE45_RS13755	COG5578	integral membrane protein
JNE45_RS13760	COG0673	inositol 2-dehydrogenase activity
JNE45_RS13765	COG1653	transport
JNE45_RS13770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JNE45_RS13775	COG4209	transmembrane transport
JNE45_RS13780	COG2207	Transcriptional regulator
JNE45_RS13785	COG1733	regulation of RNA biosynthetic process
JNE45_RS13790	COG2814	Major facilitator Superfamily
JNE45_RS13795	COG0656	L-ascorbic acid biosynthetic process
JNE45_RS13800	COG1653	transport
JNE45_RS13805	COG0395	ABC-type sugar transport system, permease component
JNE45_RS13810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE45_RS13815	COG1073	alpha beta
JNE45_RS13820	COG0495	leucyl-tRNA aminoacylation
JNE45_RS13830	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS13830	COG2202	Pas domain
JNE45_RS13835	COG2433	Pfam Transposase IS66
JNE45_RS13840	COG0577	efflux transmembrane transporter activity
JNE45_RS13845	COG1136	(ABC) transporter
JNE45_RS13855	COG1131	(ABC) transporter
JNE45_RS13860	COG1725	Transcriptional regulator
JNE45_RS13875	COG1242	4 iron, 4 sulfur cluster binding
JNE45_RS13880	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JNE45_RS13890	COG2267	carboxylic ester hydrolase activity
JNE45_RS13895	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JNE45_RS13900	COG0367	asparagine synthase
JNE45_RS13905	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JNE45_RS13910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JNE45_RS13920	COG1506	peptidase
JNE45_RS13925	COG1233	COG1233 Phytoene dehydrogenase and related
JNE45_RS13945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JNE45_RS13950	COG1116	anion transmembrane transporter activity
JNE45_RS13955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JNE45_RS13960	COG0494	nUDIX hydrolase
JNE45_RS13965	COG2310	stress, protein
JNE45_RS13980	COG4824	toxin secretion phage lysis holin
JNE45_RS13990	COG0783	Belongs to the Dps family
JNE45_RS14005	COG1854	S-ribosylhomocysteine lyase activity
JNE45_RS14010	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JNE45_RS14015	COG0288	reversible hydration of carbon dioxide
JNE45_RS14020	COG3443	Belongs to the bacterial solute-binding protein 9 family
JNE45_RS14020	COG0803	Belongs to the bacterial solute-binding protein 9 family
JNE45_RS14025	COG0254	rRNA binding
JNE45_RS14030	COG1271	oxidase subunit
JNE45_RS14035	COG1294	oxidase, subunit
JNE45_RS14050	COG4948	Mandelate Racemase Muconate Lactonizing
JNE45_RS14055	COG0318	PFAM AMP-dependent synthetase and ligase
JNE45_RS14060	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JNE45_RS14065	COG0596	Alpha beta hydrolase
JNE45_RS14070	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JNE45_RS14075	COG1169	isochorismate synthase
JNE45_RS14080	COG1575	Belongs to the MenA family. Type 1 subfamily
JNE45_RS14085	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JNE45_RS14215	COG3859	Proton-coupled thiamine transporter YuaJ
JNE45_RS14220	COG1247	-acetyltransferase
JNE45_RS14225	COG3339	Conserved Protein
JNE45_RS14235	COG0772	Belongs to the SEDS family
JNE45_RS14240	COG2268	Band 7 protein
JNE45_RS14245	COG1585	Membrane protein implicated in regulation of membrane protease activity
JNE45_RS14250	COG2318	DinB family
JNE45_RS14255	COG1454	alcohol dehydrogenase
JNE45_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS14265	COG1510	regulation of RNA biosynthetic process
JNE45_RS14280	COG5632	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS14280	COG3409	Peptidoglycan-binding domain 1 protein
JNE45_RS14325	COG3778	Protein conserved in bacteria
JNE45_RS14330	COG3299	homolog of phage Mu protein gp47
JNE45_RS14335	COG3628	GPW Gp25 family protein
JNE45_RS14345	COG4193	domain, Protein
JNE45_RS14350	COG1652	LysM domain
JNE45_RS14355	COG3953	SLT domain
JNE45_RS14355	COG5280	Phage tail tape measure protein TP901
JNE45_RS14355	COG3953	SLT domain
JNE45_RS14355	COG5280	Phage tail tape measure protein TP901
JNE45_RS14405	COG4653	Phage capsid family
JNE45_RS14410	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JNE45_RS14415	COG5518	Phage portal protein
JNE45_RS14420	COG1783	phage Terminase large subunit
JNE45_RS14425	COG5484	DNA packaging
JNE45_RS14430	COG1595	DNA-templated transcription, initiation
JNE45_RS14440	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JNE45_RS14460	COG1396	sequence-specific DNA binding
JNE45_RS14470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JNE45_RS14485	COG0628	permease
JNE45_RS14495	COG0673	inositol 2-dehydrogenase activity
JNE45_RS14500	COG0693	protein deglycase activity
JNE45_RS14505	COG0840	transmembrane signaling receptor activity
JNE45_RS14510	COG0840	transmembrane signaling receptor activity
JNE45_RS14515	COG0840	transmembrane signaling receptor activity
JNE45_RS14520	COG0840	transmembrane signaling receptor activity
JNE45_RS14535	COG2070	2-Nitropropane dioxygenase
JNE45_RS14540	COG0432	Pfam Uncharacterised protein family UPF0047
JNE45_RS14545	COG1253	flavin adenine dinucleotide binding
JNE45_RS14550	COG2738	Putative neutral zinc metallopeptidase
JNE45_RS14560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JNE45_RS14575	COG0166	Belongs to the GPI family
JNE45_RS14580	COG1979	alcohol dehydrogenase
JNE45_RS14585	COG1979	alcohol dehydrogenase
JNE45_RS14590	COG2155	Conserved Protein
JNE45_RS14595	COG1098	S1 RNA binding domain
JNE45_RS14600	COG0436	Aminotransferase
JNE45_RS14605	COG1522	sequence-specific DNA binding
JNE45_RS14610	COG2267	carboxylic ester hydrolase activity
JNE45_RS14620	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JNE45_RS14625	COG2205	protein histidine kinase activity
JNE45_RS14640	COG5018	Exonuclease
JNE45_RS14645	COG2814	Major facilitator Superfamily
JNE45_RS14650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE45_RS14655	COG3011	Protein conserved in bacteria
JNE45_RS14665	COG3290	protein histidine kinase activity
JNE45_RS14670	COG4565	transcriptional regulatory protein
JNE45_RS14675	COG1744	ABC transporter substrate-binding protein PnrA-like
JNE45_RS14680	COG3845	ABC transporter
JNE45_RS14685	COG4603	Belongs to the binding-protein-dependent transport system permease family
JNE45_RS14690	COG1079	Belongs to the binding-protein-dependent transport system permease family
JNE45_RS14695	COG3493	citrate carrier protein
JNE45_RS14705	COG2111	Na H antiporter
JNE45_RS14705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JNE45_RS14710	COG2111	Na H antiporter
JNE45_RS14715	COG1006	Multisubunit Na H antiporter MnhC subunit
JNE45_RS14720	COG0651	ATP synthesis coupled electron transport
JNE45_RS14725	COG1863	multisubunit Na H antiporter MnhE subunit
JNE45_RS14730	COG2212	antiporter activity
JNE45_RS14735	COG1320	monovalent cation:proton antiporter activity
JNE45_RS14740	COG2050	protein possibly involved in aromatic compounds catabolism
JNE45_RS14745	COG2197	response regulator
JNE45_RS14750	COG4585	Histidine kinase
JNE45_RS14760	COG0142	geranyltranstransferase activity
JNE45_RS14775	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JNE45_RS14780	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JNE45_RS14785	COG1335	isochorismatase
JNE45_RS14790	COG5506	Protein of unknown function (DUF1694)
JNE45_RS14810	COG0628	permease
JNE45_RS14825	COG1418	mRNA catabolic process
JNE45_RS14830	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS14840	COG1511	domain protein
JNE45_RS14845	COG1674	ftsk spoiiie
JNE45_RS14845	COG0433	COG0433 Predicted ATPase
JNE45_RS14850	COG4499	WXG100 protein secretion system (Wss), protein YukC
JNE45_RS14855	COG5417	Belongs to the EsaB family
JNE45_RS14860	COG4842	Belongs to the WXG100 family
JNE45_RS14865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JNE45_RS14865	COG2508	Transcriptional regulator
JNE45_RS14870	COG0686	Belongs to the AlaDH PNT family
JNE45_RS14875	COG1268	BioY protein
JNE45_RS14880	COG4326	sporulation control protein
JNE45_RS14885	COG2056	Na+-H+ antiporter family
JNE45_RS14890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JNE45_RS14895	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JNE45_RS14900	COG3584	3D domain protein
JNE45_RS14915	COG1252	NADH dehydrogenase
JNE45_RS14920	COG0492	ferredoxin-NADP+ reductase activity
JNE45_RS14930	COG0789	Transcriptional regulator
JNE45_RS14935	COG5504	Zn-dependent protease
JNE45_RS14940	COG0316	Belongs to the HesB IscA family
JNE45_RS14945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JNE45_RS14950	COG4844	belongs to the
JNE45_RS14955	COG1252	NADH dehydrogenase
JNE45_RS14965	COG4837	Protein of unknown function (DUF1462)
JNE45_RS14970	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JNE45_RS14975	COG1506	peptidase
JNE45_RS14975	COG4946	Tricorn protease homolog
JNE45_RS14975	COG0823	Involved in the tonB-independent uptake of proteins
JNE45_RS14980	COG0083	homoserine kinase activity
JNE45_RS14985	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JNE45_RS14990	COG0460	homoserine dehydrogenase
JNE45_RS14995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE45_RS15000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JNE45_RS15005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JNE45_RS15010	COG0647	UMP catabolic process
JNE45_RS15015	COG2445	Protein of unknown function DUF86
JNE45_RS15020	COG4470	Protein conserved in bacteria
JNE45_RS15030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JNE45_RS15035	COG0739	heme binding
JNE45_RS15045	COG3377	Domain of unknown function (DUF1805)
JNE45_RS15050	COG0737	Belongs to the 5'-nucleotidase family
JNE45_RS15055	COG1801	Protein of unknown function DUF72
JNE45_RS15060	COG2508	Transcriptional regulator
JNE45_RS15065	COG2140	Oxalate decarboxylase
JNE45_RS15075	COG2814	Major facilitator Superfamily
JNE45_RS15080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JNE45_RS15085	COG2356	endonuclease I
JNE45_RS15095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS15125	COG5002	protein histidine kinase activity
JNE45_RS15125	COG0642	Histidine kinase
JNE45_RS15130	COG0745	RESPONSE REGULATOR receiver
JNE45_RS15135	COG2311	Membrane
JNE45_RS15145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JNE45_RS15150	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE45_RS15155	COG1309	transcriptional regulator
JNE45_RS15165	COG0719	Fe-S assembly protein
JNE45_RS15170	COG0822	iron-sulfur transferase activity
JNE45_RS15175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JNE45_RS15180	COG0719	Fe-S assembly protein
JNE45_RS15185	COG0396	ATPase activity
JNE45_RS15195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JNE45_RS15200	COG1464	Belongs to the NlpA lipoprotein family
JNE45_RS15205	COG2011	ABC-type metal ion transport system permease component
JNE45_RS15210	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JNE45_RS15220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS15225	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JNE45_RS15235	COG0509	glycine decarboxylation via glycine cleavage system
JNE45_RS15240	COG1393	Belongs to the ArsC family
JNE45_RS15245	COG1960	acyl-CoA dehydrogenase activity
JNE45_RS15250	COG0183	Belongs to the thiolase family
JNE45_RS15255	COG1024	Enoyl-CoA hydratase
JNE45_RS15255	COG1250	3-hydroxyacyl-CoA dehydrogenase
JNE45_RS15270	COG5577	PFAM Coat F domain
JNE45_RS15280	COG1120	ATPase activity
JNE45_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS15295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE45_RS15300	COG0745	RESPONSE REGULATOR receiver
JNE45_RS15305	COG2205	protein histidine kinase activity
JNE45_RS15305	COG2770	Histidine kinase
JNE45_RS15315	COG1309	transcriptional regulator
JNE45_RS15325	COG0114	fumarate hydratase activity
JNE45_RS15335	COG0697	spore germination
JNE45_RS15340	COG0814	amino acid
JNE45_RS15355	COG2197	response regulator
JNE45_RS15360	COG4585	Histidine kinase
JNE45_RS15365	COG4758	membrane
JNE45_RS15375	COG1842	Phage shock protein A
JNE45_RS15380	COG4758	membrane
JNE45_RS15390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS15395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS15405	COG2096	Adenosyltransferase
JNE45_RS15415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JNE45_RS15425	COG2204	response regulator
JNE45_RS15440	COG1454	alcohol dehydrogenase
JNE45_RS15445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JNE45_RS15450	COG1120	ATPase activity
JNE45_RS15455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS15470	COG2721	sulfolactate sulfo-lyase activity
JNE45_RS15475	COG0246	Mannitol dehydrogenase
JNE45_RS15480	COG1609	Transcriptional regulator
JNE45_RS15485	COG1904	glucuronate isomerase
JNE45_RS15490	COG2205	protein histidine kinase activity
JNE45_RS15495	COG0745	RESPONSE REGULATOR receiver
JNE45_RS15500	COG1120	ATPase activity
JNE45_RS15505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15515	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS15520	COG0531	amino acid
JNE45_RS15535	COG1988	membrane-bound metal-dependent
JNE45_RS15540	COG1368	sulfuric ester hydrolase activity
JNE45_RS15545	COG0725	ABC transporter, periplasmic molybdate-binding protein
JNE45_RS15550	COG4149	molybdate abc transporter
JNE45_RS15555	COG0656	L-ascorbic acid biosynthetic process
JNE45_RS15560	COG1940	carbohydrate kinase activity
JNE45_RS15565	COG0025	NhaP-type Na H and K H
JNE45_RS15570	COG2860	membrane
JNE45_RS15575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JNE45_RS15580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JNE45_RS15585	COG2217	Heavy metal translocating P-type atpase
JNE45_RS15590	COG1121	(ABC) transporter
JNE45_RS15595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JNE45_RS15600	COG0803	Belongs to the bacterial solute-binding protein 9 family
JNE45_RS15610	COG3226	Transcriptional regulator
JNE45_RS15615	COG0784	Response regulator, receiver
JNE45_RS15620	COG4191	Histidine kinase
JNE45_RS15625	COG1027	Aspartate ammonia-lyase
JNE45_RS15635	COG2217	Heavy metal translocating P-type atpase
JNE45_RS15640	COG2608	mercury ion transmembrane transporter activity
JNE45_RS15645	COG1937	Protein conserved in bacteria
JNE45_RS15680	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JNE45_RS15685	COG0557	exoribonuclease II activity
JNE45_RS15690	COG1647	Serine aminopeptidase, S33
JNE45_RS15695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JNE45_RS15700	COG2002	toxin-antitoxin pair type II binding
JNE45_RS15705	COG1476	TRANSCRIPTIONal
JNE45_RS15710	COG1396	sequence-specific DNA binding
JNE45_RS15715	COG1396	sequence-specific DNA binding
JNE45_RS15720	COG1733	regulation of RNA biosynthetic process
JNE45_RS15725	COG1174	glycine betaine transport
JNE45_RS15730	COG1732	Glycine betaine
JNE45_RS15735	COG1174	glycine betaine transport
JNE45_RS15740	COG1125	glycine betaine transport
JNE45_RS15740	COG0517	IMP dehydrogenase activity
JNE45_RS15745	COG1510	regulation of RNA biosynthetic process
JNE45_RS15750	COG2095	MarC family integral membrane protein
JNE45_RS15760	COG0456	acetyltransferase
JNE45_RS15780	COG1122	ATPase activity
JNE45_RS15790	COG0148	phosphopyruvate hydratase activity
JNE45_RS15795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JNE45_RS15800	COG0149	triose-phosphate isomerase activity
JNE45_RS15805	COG0126	phosphoglycerate kinase activity
JNE45_RS15810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JNE45_RS15815	COG2390	Transcriptional regulator
JNE45_RS15820	COG0833	amino acid
JNE45_RS15825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JNE45_RS15830	COG3829	transcription factor binding
JNE45_RS15835	COG2186	Transcriptional regulator
JNE45_RS15840	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JNE45_RS15850	COG0534	Mate efflux family protein
JNE45_RS15860	COG0444	Belongs to the ABC transporter superfamily
JNE45_RS15865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JNE45_RS15870	COG0601	transmembrane transport
JNE45_RS15875	COG0747	negative chemotaxis
JNE45_RS15880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE45_RS15885	COG0110	maltose O-acetyltransferase activity
JNE45_RS15890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JNE45_RS15895	COG2244	polysaccharide biosynthetic process
JNE45_RS15900	COG5039	Polysaccharide pyruvyl transferase
JNE45_RS15905	COG1216	Glycosyl transferase, family 2
JNE45_RS15915	COG0438	transferase activity, transferring glycosyl groups
JNE45_RS15920	COG1215	transferase activity, transferring glycosyl groups
JNE45_RS15925	COG0438	transferase activity, transferring glycosyl groups
JNE45_RS15930	COG1086	Polysaccharide biosynthesis protein
JNE45_RS15935	COG0489	protein tyrosine kinase activity
JNE45_RS15940	COG3944	biosynthesis protein
JNE45_RS15945	COG1396	sequence-specific DNA binding
JNE45_RS15955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS15960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS15970	COG0726	polysaccharide deacetylase
JNE45_RS15975	COG0488	(ABC) transporter
JNE45_RS15980	COG1819	glycosyl
JNE45_RS16005	COG0740	serine-type endopeptidase activity
JNE45_RS16010	COG1611	Belongs to the LOG family
JNE45_RS16015	COG1694	Mazg nucleotide pyrophosphohydrolase
JNE45_RS16020	COG0659	secondary active sulfate transmembrane transporter activity
JNE45_RS16025	COG0288	reversible hydration of carbon dioxide
JNE45_RS16030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JNE45_RS16040	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JNE45_RS16045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS16050	COG1481	regulation of sporulation
JNE45_RS16055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JNE45_RS16060	COG1660	Displays ATPase and GTPase activities
JNE45_RS16065	COG1051	belongs to the nudix hydrolase family
JNE45_RS16070	COG0492	ferredoxin-NADP+ reductase activity
JNE45_RS16075	COG0791	NLP P60 protein
JNE45_RS16075	COG3883	PFAM NLP P60 protein
JNE45_RS16080	COG0457	Tetratricopeptide repeat
JNE45_RS16085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JNE45_RS16085	COG0140	phosphoribosyl-ATP diphosphatase activity
JNE45_RS16090	COG0107	imidazoleglycerol-phosphate synthase activity
JNE45_RS16095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JNE45_RS16100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JNE45_RS16105	COG0131	Imidazoleglycerol-phosphate dehydratase
JNE45_RS16110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JNE45_RS16115	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JNE45_RS16120	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JNE45_RS16125	COG4990	cell redox homeostasis
JNE45_RS16135	COG2910	NAD(P)H-binding
JNE45_RS16140	COG1959	2 iron, 2 sulfur cluster binding
JNE45_RS16145	COG0110	maltose O-acetyltransferase activity
JNE45_RS16150	COG0546	phosphoglycolate phosphatase activity
JNE45_RS16155	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JNE45_RS16160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JNE45_RS16165	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JNE45_RS16170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JNE45_RS16175	COG0363	glucosamine-6-phosphate deaminase activity
JNE45_RS16180	COG2188	Transcriptional regulator
JNE45_RS16185	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JNE45_RS16190	COG1950	PFAM Membrane protein of
JNE45_RS16195	COG1983	PspC domain protein
JNE45_RS16200	COG3595	metallopeptidase activity
JNE45_RS16215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JNE45_RS16225	COG4897	Protein conserved in bacteria
JNE45_RS16230	COG0574	Belongs to the PEP-utilizing enzyme family
JNE45_RS16230	COG3848	Pyruvate phosphate dikinase
JNE45_RS16235	COG1309	transcriptional regulator
JNE45_RS16240	COG2814	Major facilitator Superfamily
JNE45_RS16250	COG0745	RESPONSE REGULATOR receiver
JNE45_RS16255	COG5002	protein histidine kinase activity
JNE45_RS16260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JNE45_RS16265	COG0463	Glycosyl transferase, family 2
JNE45_RS16270	COG1113	amino acid transport
JNE45_RS16275	COG0778	Nitroreductase
JNE45_RS16280	COG1733	regulation of RNA biosynthetic process
JNE45_RS16285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE45_RS16295	COG0793	Belongs to the peptidase S41A family
JNE45_RS16295	COG3409	Peptidoglycan-binding domain 1 protein
JNE45_RS16300	COG0730	response to heat
JNE45_RS16305	COG0791	NLP P60 protein
JNE45_RS16305	COG3883	PFAM NLP P60 protein
JNE45_RS16310	COG2177	Part of the ABC transporter FtsEX involved in
JNE45_RS16315	COG2884	Cell division ATP-binding protein ftsE
JNE45_RS16320	COG2010	Cytochrome c
JNE45_RS16325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JNE45_RS16345	COG0653	protein targeting
JNE45_RS16350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JNE45_RS16355	COG0840	transmembrane signaling receptor activity
JNE45_RS16370	COG1516	flagellar protein fliS
JNE45_RS16375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JNE45_RS16380	COG1334	flagellar protein FlaG
JNE45_RS16385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JNE45_RS16390	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JNE45_RS16400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JNE45_RS16405	COG4786	Flagellar basal body rod
JNE45_RS16405	COG1256	bacterial-type flagellum assembly
JNE45_RS16410	COG3418	PFAM FlgN family protein
JNE45_RS16425	COG1040	competence protein
JNE45_RS16435	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JNE45_RS16440	COG1307	EDD domain protein, DegV family
JNE45_RS16445	COG2197	response regulator
JNE45_RS16450	COG4585	Histidine kinase
JNE45_RS16455	COG1739	Uncharacterized protein family UPF0029
JNE45_RS16460	COG1316	TRANSCRIPTIONal
JNE45_RS16465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JNE45_RS16470	COG0438	transferase activity, transferring glycosyl groups
JNE45_RS16475	COG1215	transferase activity, transferring glycosyl groups
JNE45_RS16480	COG3206	protein involved in exopolysaccharide biosynthesis
JNE45_RS16485	COG3307	-O-antigen
JNE45_RS16490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JNE45_RS16495	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JNE45_RS16500	COG0297	glycogen (starch) synthase activity
JNE45_RS16500	COG0438	transferase activity, transferring glycosyl groups
JNE45_RS16505	COG2244	polysaccharide biosynthetic process
JNE45_RS16520	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS16520	COG2247	cell wall binding repeat
JNE45_RS16525	COG0860	N-Acetylmuramoyl-L-alanine amidase
JNE45_RS16525	COG2247	cell wall binding repeat
JNE45_RS16530	COG2385	sporulation resulting in formation of a cellular spore
JNE45_RS16530	COG2247	cell wall binding repeat
JNE45_RS16540	COG1316	TRANSCRIPTIONal
JNE45_RS16545	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JNE45_RS16550	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JNE45_RS16555	COG1134	teichoic acid transport
JNE45_RS16560	COG1682	transport, permease protein
JNE45_RS16565	COG1216	Glycosyl transferase, family 2
JNE45_RS16575	COG1181	Belongs to the D-alanine--D-alanine ligase family
JNE45_RS16580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE45_RS16590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNE45_RS16595	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE45_RS16605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JNE45_RS16610	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JNE45_RS16615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE45_RS16620	COG4193	domain, Protein
JNE45_RS16625	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE45_RS16625	COG0463	Glycosyl transferase, family 2
JNE45_RS16630	COG1482	cell wall glycoprotein biosynthetic process
JNE45_RS16640	COG1175	transmembrane transport
JNE45_RS16645	COG1653	transport
JNE45_RS16650	COG2197	response regulator
JNE45_RS16655	COG2972	Histidine kinase
JNE45_RS16665	COG0454	-acetyltransferase
JNE45_RS16670	COG0800	Aldolase
JNE45_RS16675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNE45_RS16680	COG1609	Transcriptional regulator
JNE45_RS16685	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JNE45_RS16690	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS16695	COG0697	spore germination
JNE45_RS16700	COG0814	amino acid
JNE45_RS16715	COG2814	Major facilitator Superfamily
JNE45_RS16720	COG1316	TRANSCRIPTIONal
JNE45_RS16725	COG0561	phosphatase activity
JNE45_RS16730	COG0791	NLP P60 protein
JNE45_RS16740	COG2843	Capsule synthesis protein
JNE45_RS16750	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JNE45_RS16755	COG0697	spore germination
JNE45_RS16770	COG1609	Transcriptional regulator
JNE45_RS16775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JNE45_RS16780	COG1869	D-ribose catabolic process
JNE45_RS16785	COG1129	ABC transporter
JNE45_RS16790	COG1172	Belongs to the binding-protein-dependent transport system permease family
JNE45_RS16795	COG1879	ABC-type sugar transport system periplasmic component
JNE45_RS16800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JNE45_RS16805	COG0583	DNA-binding transcription factor activity
JNE45_RS16810	COG0028	Belongs to the TPP enzyme family
JNE45_RS16815	COG3527	Alpha-acetolactate decarboxylase
JNE45_RS16820	COG1522	sequence-specific DNA binding
JNE45_RS16825	COG2059	Chromate
JNE45_RS16830	COG2059	Chromate
JNE45_RS16835	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JNE45_RS16845	COG4715	Zinc finger, swim domain protein
JNE45_RS16850	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JNE45_RS16855	COG2202	Pas domain
JNE45_RS16855	COG1366	Belongs to the anti-sigma-factor antagonist family
JNE45_RS16860	COG0561	phosphatase activity
JNE45_RS16875	COG1970	mechanosensitive ion channel activity
JNE45_RS16880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JNE45_RS16885	COG0457	Tetratricopeptide repeat
JNE45_RS16890	COG4786	Flagellar basal body rod
JNE45_RS16895	COG4786	Flagellar basal body rod
JNE45_RS16900	COG1077	Cell shape determining protein MreB Mrl
JNE45_RS16905	COG1609	Transcriptional regulator
JNE45_RS16910	COG1846	Transcriptional regulator
JNE45_RS16915	COG2814	Major facilitator Superfamily
JNE45_RS16920	COG0671	phosphoesterase, PA-phosphatase related
JNE45_RS16925	COG0477	Major facilitator Superfamily
JNE45_RS16930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS16935	COG0765	amino acid transport
JNE45_RS16945	COG0004	ammonium transporteR
JNE45_RS16950	COG0347	Belongs to the P(II) protein family
JNE45_RS16955	COG0739	heme binding
JNE45_RS16960	COG1247	-acetyltransferase
JNE45_RS16995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JNE45_RS17000	COG0523	cobalamin synthesis protein
JNE45_RS17005	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JNE45_RS17015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JNE45_RS17020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JNE45_RS17025	COG2223	nitrite transmembrane transporter activity
JNE45_RS17030	COG0243	molybdopterin cofactor binding
JNE45_RS17035	COG2304	oxidoreductase activity
JNE45_RS17040	COG2304	oxidoreductase activity
JNE45_RS17045	COG2385	sporulation resulting in formation of a cellular spore
JNE45_RS17050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNE45_RS17060	COG4836	Membrane
JNE45_RS17070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JNE45_RS17075	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JNE45_RS17080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JNE45_RS17085	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JNE45_RS17090	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNE45_RS17095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JNE45_RS17100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JNE45_RS17105	COG0356	it plays a direct role in the translocation of protons across the membrane
JNE45_RS17115	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JNE45_RS17120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JNE45_RS17125	COG4475	Protein of unknown function (DUF436)
JNE45_RS17130	COG0698	ribose 5-phosphate isomerase
JNE45_RS17135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JNE45_RS17140	COG1971	Probably functions as a manganese efflux pump
JNE45_RS17145	COG0009	L-threonylcarbamoyladenylate synthase
JNE45_RS17150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JNE45_RS17165	COG2890	protein-(glutamine-N5) methyltransferase activity
JNE45_RS17170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JNE45_RS17175	COG0789	Transcriptional regulator
JNE45_RS17180	COG0679	Auxin Efflux Carrier
JNE45_RS17185	COG0281	malic enzyme
JNE45_RS17190	COG1435	thymidine kinase activity
JNE45_RS17195	COG0254	rRNA binding
JNE45_RS17200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JNE45_RS17205	COG1494	fructose-1,6-bisphosphatase
JNE45_RS17210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JNE45_RS17215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JNE45_RS17220	COG0191	fructose-bisphosphate aldolase activity
JNE45_RS17225	COG2204	response regulator
JNE45_RS17230	COG4821	SIS domain
JNE45_RS17235	COG0504	CTP synthase activity
JNE45_RS17240	COG3343	RNA polymerase activity
JNE45_RS17250	COG1960	acyl-CoA dehydrogenase activity
JNE45_RS17255	COG1960	acyl-CoA dehydrogenase activity
JNE45_RS17260	COG1250	3-hydroxyacyl-CoA dehydrogenase
JNE45_RS17265	COG0183	Belongs to the thiolase family
JNE45_RS17270	COG0247	lactate metabolic process
JNE45_RS17270	COG2181	nitrate reductase activity
JNE45_RS17275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE45_RS17280	COG4294	response to UV
JNE45_RS17290	COG1619	proteins homologs of microcin C7 resistance protein MccF
JNE45_RS17310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JNE45_RS17325	COG0018	arginyl-trna synthetase
JNE45_RS17330	COG4506	Protein conserved in bacteria
JNE45_RS17340	COG0010	Belongs to the arginase family
JNE45_RS17345	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JNE45_RS17350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JNE45_RS17360	COG1994	Peptidase M50
JNE45_RS17365	COG1942	4-Oxalocrotonate Tautomerase
JNE45_RS17375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS17380	COG0583	DNA-binding transcription factor activity
JNE45_RS17385	COG0431	NADPH-dependent FMN reductase
JNE45_RS17390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS17395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JNE45_RS17400	COG0454	-acetyltransferase
JNE45_RS17405	COG0765	amino acid transport
JNE45_RS17410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS17420	COG1126	abc transporter atp-binding protein
JNE45_RS17425	COG3465	dGTPase activity
JNE45_RS17430	COG1078	dGTPase activity
JNE45_RS17435	COG4844	belongs to the
JNE45_RS17510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JNE45_RS17520	COG0280	phosphate acetyltransferase
JNE45_RS17530	COG2814	Major facilitator Superfamily
JNE45_RS17535	COG1522	sequence-specific DNA binding
JNE45_RS17540	COG2814	Major facilitator Superfamily
JNE45_RS17545	COG0077	Prephenate dehydratase
JNE45_RS17555	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS17560	COG0151	Belongs to the GarS family
JNE45_RS17565	COG0436	Aminotransferase
JNE45_RS17570	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS17575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JNE45_RS17580	COG1091	dTDP-4-dehydrorhamnose reductase activity
JNE45_RS17585	COG1088	dTDP-glucose 4,6-dehydratase activity
JNE45_RS17590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JNE45_RS17595	COG3980	spore coat polysaccharide biosynthesis protein
JNE45_RS17600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JNE45_RS17605	COG2089	acid synthase
JNE45_RS17610	COG0456	acetyltransferase
JNE45_RS17615	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JNE45_RS17620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JNE45_RS17625	COG0463	Glycosyl transferase, family 2
JNE45_RS17645	COG2363	Small membrane protein
JNE45_RS17650	COG2233	PERMEase
JNE45_RS17660	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS17665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JNE45_RS17670	COG1216	Glycosyl transferase, family 2
JNE45_RS17680	COG0351	phosphomethylpyrimidine kinase
JNE45_RS17700	COG3964	amidohydrolase
JNE45_RS17710	COG1621	beta-fructofuranosidase activity
JNE45_RS17715	COG1263	PTS System
JNE45_RS17715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS17720	COG3711	transcriptional antiterminator
JNE45_RS17730	COG1404	Belongs to the peptidase S8 family
JNE45_RS17735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JNE45_RS17740	COG0778	Nitroreductase
JNE45_RS17745	COG0772	Belongs to the SEDS family
JNE45_RS17755	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JNE45_RS17760	COG1845	cytochrome c oxidase, subunit III
JNE45_RS17765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JNE45_RS17770	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JNE45_RS17780	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JNE45_RS17785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JNE45_RS17790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JNE45_RS17805	COG2246	polysaccharide biosynthetic process
JNE45_RS17825	COG3162	membrane
JNE45_RS17830	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JNE45_RS17845	COG0352	thiamine-phosphate diphosphorylase activity
JNE45_RS17850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JNE45_RS17855	COG0583	DNA-binding transcription factor activity
JNE45_RS17860	COG1380	Effector of murein hydrolase LrgA
JNE45_RS17865	COG1346	cytolysis
JNE45_RS17870	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JNE45_RS17875	COG0346	lactoylglutathione lyase activity
JNE45_RS17885	COG0765	amino acid transport
JNE45_RS17890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JNE45_RS17895	COG0457	Tetratricopeptide repeat
JNE45_RS17905	COG2357	RelA SpoT domain protein
JNE45_RS17910	COG1172	Belongs to the binding-protein-dependent transport system permease family
JNE45_RS17915	COG1129	ABC transporter
JNE45_RS17925	COG3420	alginic acid biosynthetic process
JNE45_RS17930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JNE45_RS17940	COG1486	melibiose metabolic process
JNE45_RS17945	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE45_RS17950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS17955	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS17960	COG3711	transcriptional antiterminator
JNE45_RS17960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS17975	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JNE45_RS17990	COG1595	DNA-templated transcription, initiation
JNE45_RS18000	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JNE45_RS18005	COG4988	ABC transporter
JNE45_RS18010	COG1294	oxidase, subunit
JNE45_RS18015	COG1271	oxidase subunit
JNE45_RS18025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JNE45_RS18035	COG4509	Sortase family
JNE45_RS18060	COG5386	Cell surface protein
JNE45_RS18065	COG5386	Cell surface protein
JNE45_RS18070	COG1733	regulation of RNA biosynthetic process
JNE45_RS18075	COG2514	catechol 2,3-dioxygenase activity
JNE45_RS18080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS18080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JNE45_RS18085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE45_RS18085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JNE45_RS18090	COG0346	lactoylglutathione lyase activity
JNE45_RS18095	COG0726	polysaccharide deacetylase
JNE45_RS18100	COG1447	Phosphotransferase system cellobiose-specific component IIA
JNE45_RS18105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS18110	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS18115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JNE45_RS18120	COG3711	transcriptional antiterminator
JNE45_RS18120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JNE45_RS18145	COG1757	Na H antiporter
JNE45_RS18150	COG1027	Aspartate ammonia-lyase
JNE45_RS18155	COG0252	asparaginase activity
JNE45_RS18160	COG1396	sequence-specific DNA binding
JNE45_RS18185	COG4842	Belongs to the WXG100 family
JNE45_RS18190	COG2195	Cleaves the N-terminal amino acid of tripeptides
JNE45_RS18205	COG1737	Transcriptional regulator
JNE45_RS18210	COG2084	Dehydrogenase
JNE45_RS18220	COG2610	gluconate transmembrane transporter activity
JNE45_RS18225	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JNE45_RS18230	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS18235	COG1263	PTS System
JNE45_RS18235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS18235	COG2190	(PTS) system
JNE45_RS18240	COG3711	transcriptional antiterminator
JNE45_RS18245	COG3878	Protein conserved in bacteria
JNE45_RS18255	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE45_RS18260	COG1122	ATPase activity
JNE45_RS18265	COG4721	ABC-type cobalt transport system, permease component
JNE45_RS18270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JNE45_RS18305	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JNE45_RS18310	COG0778	Nitroreductase
JNE45_RS18315	COG1846	Transcriptional regulator
JNE45_RS18320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JNE45_RS18325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JNE45_RS18330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JNE45_RS18335	COG2390	Transcriptional regulator
JNE45_RS18345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JNE45_RS18345	COG2755	lipolytic protein G-D-S-L family
JNE45_RS18365	COG0561	phosphatase activity
JNE45_RS18370	COG0789	Transcriptional regulator
JNE45_RS18375	COG0673	inositol 2-dehydrogenase activity
JNE45_RS18380	COG0840	transmembrane signaling receptor activity
JNE45_RS18385	COG1113	amino acid transport
JNE45_RS18390	COG4335	DNA alkylation repair
JNE45_RS18400	COG1070	Carbohydrate kinase
JNE45_RS18405	COG1737	Transcriptional regulator
JNE45_RS18440	COG0583	DNA-binding transcription factor activity
JNE45_RS18445	COG1609	Transcriptional regulator
JNE45_RS18450	COG2182	Extracellular solute-binding protein
JNE45_RS18455	COG1175	transmembrane transport
JNE45_RS18460	COG3833	ABC-type maltose transport systems, permease component
JNE45_RS18470	COG1874	Beta-galactosidase
JNE45_RS18475	COG2851	Citrate transporter
JNE45_RS18485	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JNE45_RS18490	COG1131	(ABC) transporter
JNE45_RS18495	COG2824	Alkylphosphonate utilization operon protein PhnA
JNE45_RS18500	COG1929	Belongs to the glycerate kinase type-1 family
JNE45_RS18505	COG2610	gluconate transmembrane transporter activity
JNE45_RS18510	COG3835	regulator
JNE45_RS18515	COG1309	transcriptional regulator
JNE45_RS18520	COG2814	Major facilitator Superfamily
JNE45_RS18530	COG0577	efflux transmembrane transporter activity
JNE45_RS18530	COG1136	(ABC) transporter
JNE45_RS18540	COG0457	Tetratricopeptide repeat
JNE45_RS18545	COG3711	transcriptional antiterminator
JNE45_RS18550	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS18555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS18555	COG1263	PTS System
JNE45_RS18555	COG2190	(PTS) system
JNE45_RS18590	COG1113	amino acid transport
JNE45_RS18595	COG1609	Transcriptional regulator
JNE45_RS18600	COG2814	Major facilitator Superfamily
JNE45_RS18610	COG2814	Major facilitator Superfamily
JNE45_RS18615	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS18625	COG2190	(PTS) system
JNE45_RS18625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JNE45_RS18625	COG1263	PTS System
JNE45_RS18640	COG1012	belongs to the aldehyde dehydrogenase family
JNE45_RS18660	COG0163	prenyltransferase activity
JNE45_RS18665	COG0583	DNA-binding transcription factor activity
JNE45_RS18670	COG2723	6-phospho-beta-galactosidase activity
JNE45_RS18680	COG2188	Transcriptional regulator
JNE45_RS18695	COG0384	phenazine biosynthesis protein PhzF
JNE45_RS18700	COG0583	DNA-binding transcription factor activity
JNE45_RS18720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JNE45_RS18730	COG2814	Major facilitator Superfamily
JNE45_RS18735	COG0640	Transcriptional regulator
JNE45_RS18760	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JNE45_RS18770	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JNE45_RS18780	COG4720	Psort location CytoplasmicMembrane, score
JNE45_RS18800	COG0456	acetyltransferase
JNE45_RS18805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JNE45_RS18810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JNE45_RS18815	COG4853	Protein conserved in bacteria
JNE45_RS18820	COG4863	YycH protein
JNE45_RS18825	COG5002	protein histidine kinase activity
JNE45_RS18830	COG0745	RESPONSE REGULATOR receiver
JNE45_RS18855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JNE45_RS18865	COG2311	Membrane
JNE45_RS18870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JNE45_RS18875	COG1309	transcriptional regulator
JNE45_RS18880	COG2124	cytochrome p450
JNE45_RS18885	COG0346	lactoylglutathione lyase activity
JNE45_RS18890	COG0305	Participates in initiation and elongation during chromosome replication
JNE45_RS18910	COG2819	hydrolase of the alpha beta superfamily
JNE45_RS18915	COG1028	Short-chain dehydrogenase reductase Sdr
JNE45_RS18920	COG1169	isochorismate synthase
JNE45_RS18925	COG1021	2,3-dihydroxybenzoate-AMP ligase
JNE45_RS18930	COG1535	isochorismatase
JNE45_RS18930	COG3433	isochorismatase activity
JNE45_RS18935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JNE45_RS18940	COG3251	PFAM MbtH domain protein
JNE45_RS18945	COG2207	Transcriptional regulator
JNE45_RS18945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS18950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JNE45_RS18955	COG2819	hydrolase of the alpha beta superfamily
JNE45_RS18960	COG3093	addiction module antidote protein HigA
JNE45_RS18965	COG2807	transmembrane transport
JNE45_RS18970	COG0359	binds to the 23S rRNA
JNE45_RS18975	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JNE45_RS18980	COG4241	membrane
JNE45_RS18985	COG1227	inorganic diphosphatase activity
JNE45_RS18995	COG1595	DNA-templated transcription, initiation
JNE45_RS19005	COG0753	catalase activity
JNE45_RS19010	COG0655	NAD(P)H dehydrogenase (quinone) activity
JNE45_RS19015	COG0400	carboxylic ester hydrolase activity
JNE45_RS19020	COG0346	lactoylglutathione lyase activity
JNE45_RS19025	COG1174	glycine betaine transport
JNE45_RS19030	COG1125	glycine betaine transport
JNE45_RS19030	COG0517	IMP dehydrogenase activity
JNE45_RS19035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JNE45_RS19040	COG0629	single-stranded DNA binding
JNE45_RS19045	COG0360	Binds together with S18 to 16S ribosomal RNA
JNE45_RS19050	COG0012	GTP binding
JNE45_RS19055	COG4481	Protein conserved in bacteria
JNE45_RS19070	COG3949	Membrane
JNE45_RS19080	COG1475	DNA binding
JNE45_RS19085	COG1192	Involved in chromosome partitioning
JNE45_RS19090	COG1475	DNA binding
JNE45_RS19095	COG0357	Ribosomal RNA small subunit methyltransferase G
JNE45_RS19100	COG0445	tRNA wobble uridine modification
JNE45_RS19105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JNE45_RS19110	COG1847	R3H domain protein
JNE45_RS19115	COG0706	membrane insertase activity
JNE45_RS19120	COG0594	ribonuclease P activity
JNE45_RS19125	COG0230	Belongs to the bacterial ribosomal protein bL34 family