locus-tag	class	description
LGQ02_RS00010	COG0592	DNA-directed DNA polymerase activity
LGQ02_RS00015	COG2501	S4 domain
LGQ02_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LGQ02_RS00030	COG0187	DNA topoisomerase II activity
LGQ02_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGQ02_RS00060	COG2340	Cysteine-rich secretory protein family
LGQ02_RS00065	COG0626	cystathionine gamma-synthase activity
LGQ02_RS00075	COG0516	GMP reductase activity
LGQ02_RS00075	COG0517	IMP dehydrogenase activity
LGQ02_RS00085	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LGQ02_RS00090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LGQ02_RS00095	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGQ02_RS00100	COG0444	Belongs to the ABC transporter superfamily
LGQ02_RS00105	COG4608	Belongs to the ABC transporter superfamily
LGQ02_RS00115	COG0601	transmembrane transport
LGQ02_RS00120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGQ02_RS00125	COG0444	Belongs to the ABC transporter superfamily
LGQ02_RS00130	COG4608	Belongs to the ABC transporter superfamily
LGQ02_RS00140	COG0601	transmembrane transport
LGQ02_RS00145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGQ02_RS00155	COG0590	tRNA wobble adenosine to inosine editing
LGQ02_RS00170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LGQ02_RS00175	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LGQ02_RS00180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGQ02_RS00210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS00220	COG1982	Orn Lys Arg decarboxylase major
LGQ02_RS00225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGQ02_RS00230	COG3870	Protein conserved in bacteria
LGQ02_RS00235	COG0470	DNA polymerase III
LGQ02_RS00240	COG1774	PSP1 C-terminal conserved region
LGQ02_RS00245	COG4467	Involved in initiation control of chromosome replication
LGQ02_RS00250	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LGQ02_RS00255	COG2827	Endonuclease containing a URI domain
LGQ02_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGQ02_RS00265	COG2002	toxin-antitoxin pair type II binding
LGQ02_RS00270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGQ02_RS00270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGQ02_RS00275	COG0084	hydrolase, TatD family'
LGQ02_RS00280	COG3584	3D domain protein
LGQ02_RS00280	COG3583	domain protein
LGQ02_RS00290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGQ02_RS00300	COG4466	Protein conserved in bacteria
LGQ02_RS00310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LGQ02_RS00315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGQ02_RS00320	COG2088	sporulation resulting in formation of a cellular spore
LGQ02_RS00325	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LGQ02_RS00330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGQ02_RS00335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LGQ02_RS00340	COG0193	aminoacyl-tRNA hydrolase activity
LGQ02_RS00350	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGQ02_RS00355	COG2002	toxin-antitoxin pair type II binding
LGQ02_RS00360	COG2244	polysaccharide biosynthetic process
LGQ02_RS00365	COG3956	TIGRFAM MazG family protein
LGQ02_RS00370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGQ02_RS00390	COG1098	S1 RNA binding domain
LGQ02_RS00395	COG2208	phosphoserine phosphatase activity
LGQ02_RS00400	COG2304	oxidoreductase activity
LGQ02_RS00405	COG0515	serine threonine protein kinase
LGQ02_RS00410	COG2966	Psort location CytoplasmicMembrane, score
LGQ02_RS00420	COG0037	tRNA processing
LGQ02_RS00425	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LGQ02_RS00430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGQ02_RS00440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LGQ02_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGQ02_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
LGQ02_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGQ02_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGQ02_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGQ02_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGQ02_RS00475	COG1396	sequence-specific DNA binding
LGQ02_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGQ02_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGQ02_RS00580	COG1285	pathogenesis
LGQ02_RS00590	COG3880	PFAM UvrB UvrC protein
LGQ02_RS00595	COG3869	Catalyzes the specific phosphorylation of arginine residues in
LGQ02_RS00600	COG0542	response to heat
LGQ02_RS00605	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LGQ02_RS00610	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LGQ02_RS00615	COG4956	integral membrane protein (PIN domain superfamily)
LGQ02_RS00620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LGQ02_RS00625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGQ02_RS00630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LGQ02_RS00635	COG1045	serine acetyltransferase
LGQ02_RS00640	COG0215	cysteine-tRNA ligase activity
LGQ02_RS00650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGQ02_RS00655	COG3688	RNA-binding protein containing a PIN domain
LGQ02_RS00665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGQ02_RS00670	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGQ02_RS00675	COG0250	Participates in transcription elongation, termination and antitermination
LGQ02_RS00680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGQ02_RS00685	COG0081	regulation of translation
LGQ02_RS00690	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGQ02_RS00695	COG0222	ribosome binding
LGQ02_RS00700	COG2813	Specifically methylates the guanine in position
LGQ02_RS00705	COG0085	RNA polymerase activity
LGQ02_RS00710	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGQ02_RS00715	COG1358	cellular component organization or biogenesis
LGQ02_RS00720	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGQ02_RS00725	COG0049	tRNA binding
LGQ02_RS00730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LGQ02_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGQ02_RS00745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGQ02_RS00750	COG0088	Forms part of the polypeptide exit tunnel
LGQ02_RS00755	COG0089	rRNA binding
LGQ02_RS00760	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGQ02_RS00765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGQ02_RS00770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGQ02_RS00775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LGQ02_RS00780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGQ02_RS00785	COG0255	Belongs to the universal ribosomal protein uL29 family
LGQ02_RS00790	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGQ02_RS00795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGQ02_RS00800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LGQ02_RS00805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGQ02_RS00810	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGQ02_RS00815	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LGQ02_RS00820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LGQ02_RS00825	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LGQ02_RS00835	COG1841	ribosomal large subunit assembly
LGQ02_RS00840	COG0200	Binds to the 23S rRNA
LGQ02_RS00845	COG0201	protein transport
LGQ02_RS00850	COG0563	adenylate kinase activity
LGQ02_RS00855	COG0024	Methionine aminopeptidase
LGQ02_RS00865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGQ02_RS00870	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGQ02_RS00875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGQ02_RS00880	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LGQ02_RS00885	COG0202	RNA polymerase activity
LGQ02_RS00890	COG0203	ribosomal protein L17
LGQ02_RS00905	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LGQ02_RS00910	COG0101	tRNA pseudouridine synthase activity
LGQ02_RS00915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGQ02_RS00920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGQ02_RS00930	COG2885	chlorophyll binding
LGQ02_RS00955	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGQ02_RS00960	COG0489	protein tyrosine kinase activity
LGQ02_RS00970	COG2194	sulfuric ester hydrolase activity
LGQ02_RS00975	COG0726	polysaccharide deacetylase
LGQ02_RS01035	COG1595	DNA-templated transcription, initiation
LGQ02_RS01040	COG5662	AntiSigma factor
LGQ02_RS01050	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LGQ02_RS01055	COG4856	YbbR-like protein
LGQ02_RS01060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGQ02_RS01065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LGQ02_RS01075	COG1454	alcohol dehydrogenase
LGQ02_RS01075	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS01080	COG2223	nitrite transmembrane transporter activity
LGQ02_RS01095	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS01100	COG2814	Major facilitator Superfamily
LGQ02_RS01130	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
LGQ02_RS01135	COG1279	arginine transmembrane transporter activity
LGQ02_RS01150	COG2226	methyltransferase
LGQ02_RS01180	COG0702	epimerase
LGQ02_RS01190	COG2514	catechol 2,3-dioxygenase activity
LGQ02_RS01200	COG1473	amidohydrolase
LGQ02_RS01220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGQ02_RS01225	COG0569	domain protein
LGQ02_RS01230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGQ02_RS01250	COG0110	maltose O-acetyltransferase activity
LGQ02_RS01290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGQ02_RS01345	COG1151	hydroxylamine reductase activity
LGQ02_RS01360	COG3173	Aminoglycoside phosphotransferase
LGQ02_RS01375	COG0626	cystathionine gamma-synthase activity
LGQ02_RS01380	COG0626	cystathionine gamma-synthase activity
LGQ02_RS01465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LGQ02_RS01480	COG1910	domain protein
LGQ02_RS01505	COG1714	RDD family
LGQ02_RS01510	COG1283	sodium-dependent phosphate transmembrane transporter activity
LGQ02_RS01525	COG4555	ABC transporter
LGQ02_RS01570	COG2268	Band 7 protein
LGQ02_RS01610	COG2239	Acts as a magnesium transporter
LGQ02_RS01620	COG1595	DNA-templated transcription, initiation
LGQ02_RS01635	COG3103	Sh3 type 3 domain protein
LGQ02_RS01635	COG0366	Alpha amylase catalytic
LGQ02_RS01645	COG0697	spore germination
LGQ02_RS01670	COG1846	Transcriptional regulator
LGQ02_RS01675	COG0655	NAD(P)H dehydrogenase (quinone) activity
LGQ02_RS01680	COG0346	lactoylglutathione lyase activity
LGQ02_RS01695	COG0840	transmembrane signaling receptor activity
LGQ02_RS01710	COG2201	protein-glutamate methylesterase activity
LGQ02_RS01715	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LGQ02_RS01755	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGQ02_RS01770	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS01775	COG2205	protein histidine kinase activity
LGQ02_RS01780	COG0517	IMP dehydrogenase activity
LGQ02_RS01785	COG1657	PFAM Prenyltransferase squalene oxidase
LGQ02_RS01790	COG2210	Belongs to the sulfur carrier protein TusA family
LGQ02_RS01795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS01800	COG1937	Protein conserved in bacteria
LGQ02_RS01805	COG5002	protein histidine kinase activity
LGQ02_RS01810	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS01815	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS01820	COG0785	Cytochrome C biogenesis protein
LGQ02_RS01830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS01830	COG0425	Belongs to the sulfur carrier protein TusA family
LGQ02_RS01835	COG2210	Belongs to the sulfur carrier protein TusA family
LGQ02_RS01840	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS01840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS01845	COG0425	Belongs to the sulfur carrier protein TusA family
LGQ02_RS01855	COG0288	reversible hydration of carbon dioxide
LGQ02_RS01860	COG2226	methyltransferase
LGQ02_RS01865	COG1757	Na H antiporter
LGQ02_RS01870	COG1368	sulfuric ester hydrolase activity
LGQ02_RS01890	COG3559	Exporter of polyketide antibiotics
LGQ02_RS01895	COG1131	(ABC) transporter
LGQ02_RS01900	COG1309	transcriptional regulator
LGQ02_RS01925	COG1215	transferase activity, transferring glycosyl groups
LGQ02_RS01940	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGQ02_RS01960	COG2608	mercury ion transmembrane transporter activity
LGQ02_RS01965	COG2217	Heavy metal translocating P-type atpase
LGQ02_RS01975	COG4176	ABC-type proline glycine betaine transport system permease component
LGQ02_RS01980	COG0517	IMP dehydrogenase activity
LGQ02_RS01980	COG4175	Glycine betaine
LGQ02_RS02020	COG4895	conserved protein (DUF2196)
LGQ02_RS02025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LGQ02_RS02030	COG0840	transmembrane signaling receptor activity
LGQ02_RS02035	COG0656	L-ascorbic acid biosynthetic process
LGQ02_RS02045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGQ02_RS02050	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LGQ02_RS02055	COG0386	Belongs to the glutathione peroxidase family
LGQ02_RS02065	COG3832	glyoxalase III activity
LGQ02_RS02070	COG0640	Transcriptional regulator
LGQ02_RS02075	COG1295	ribonuclease BN
LGQ02_RS02080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGQ02_RS02090	COG1280	lysine exporter protein (LysE YggA)
LGQ02_RS02095	COG1113	amino acid transport
LGQ02_RS02105	COG4152	abc transporter atp-binding protein
LGQ02_RS02125	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGQ02_RS02140	COG1051	belongs to the nudix hydrolase family
LGQ02_RS02145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LGQ02_RS02155	COG0583	DNA-binding transcription factor activity
LGQ02_RS02165	COG2226	methyltransferase
LGQ02_RS02180	COG2239	Acts as a magnesium transporter
LGQ02_RS02200	COG0589	response to stress
LGQ02_RS02205	COG0659	secondary active sulfate transmembrane transporter activity
LGQ02_RS02210	COG1940	carbohydrate kinase activity
LGQ02_RS02215	COG2188	Transcriptional regulator
LGQ02_RS02220	COG4821	SIS domain
LGQ02_RS02225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGQ02_RS02230	COG0363	glucosamine-6-phosphate deaminase activity
LGQ02_RS02265	COG1847	R3H domain protein
LGQ02_RS02270	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGQ02_RS02275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGQ02_RS02280	COG1288	antiporter activity
LGQ02_RS02285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGQ02_RS02290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS02295	COG0431	NADPH-dependent FMN reductase
LGQ02_RS02300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGQ02_RS02370	COG1510	regulation of RNA biosynthetic process
LGQ02_RS02375	COG1595	DNA-templated transcription, initiation
LGQ02_RS02385	COG3829	transcription factor binding
LGQ02_RS02390	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS02395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGQ02_RS02400	COG0506	proline dehydrogenase activity
LGQ02_RS02410	COG2239	Acts as a magnesium transporter
LGQ02_RS02415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGQ02_RS02430	COG3842	ATPase activity
LGQ02_RS02435	COG0705	Rhomboid family
LGQ02_RS02445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGQ02_RS02445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGQ02_RS02450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGQ02_RS02455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGQ02_RS02460	COG0864	Transcriptional regulator
LGQ02_RS02465	COG2337	Toxic component of a toxin-antitoxin (TA) module
LGQ02_RS02470	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS02475	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS02480	COG2172	sigma factor antagonist activity
LGQ02_RS02485	COG2208	phosphoserine phosphatase activity
LGQ02_RS02490	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS02495	COG2172	sigma factor antagonist activity
LGQ02_RS02500	COG1191	sigma factor activity
LGQ02_RS02505	COG2208	phosphoserine phosphatase activity
LGQ02_RS02510	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS02515	COG2183	response to ionizing radiation
LGQ02_RS02525	COG3091	SprT-like family
LGQ02_RS02610	COG0626	cystathionine gamma-synthase activity
LGQ02_RS02615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGQ02_RS02620	COG0802	atpase or kinase
LGQ02_RS02625	COG1214	PFAM Peptidase M22, glycoprotease
LGQ02_RS02630	COG0456	acetyltransferase
LGQ02_RS02645	COG0326	Molecular chaperone. Has ATPase activity
LGQ02_RS02650	COG0488	(ABC) transporter
LGQ02_RS02660	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LGQ02_RS02665	COG2814	Major facilitator Superfamily
LGQ02_RS02670	COG0765	amino acid transport
LGQ02_RS02675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGQ02_RS02685	COG1266	CAAX protease self-immunity
LGQ02_RS02695	COG0459	protein refolding
LGQ02_RS02700	COG0582	viral genome integration into host DNA
LGQ02_RS02720	COG1484	DNA-dependent DNA replication
LGQ02_RS02740	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGQ02_RS02780	COG0456	acetyltransferase
LGQ02_RS02860	COG0433	COG0433 Predicted ATPase
LGQ02_RS02870	COG0737	Belongs to the 5'-nucleotidase family
LGQ02_RS02875	COG4667	esterase of the alpha-beta hydrolase superfamily
LGQ02_RS02880	COG3177	Filamentation induced by cAMP protein fic
LGQ02_RS02890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGQ02_RS02895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGQ02_RS02900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGQ02_RS02910	COG1120	ATPase activity
LGQ02_RS02920	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGQ02_RS02965	COG0697	spore germination
LGQ02_RS02975	COG2113	Glycine betaine
LGQ02_RS02980	COG1510	regulation of RNA biosynthetic process
LGQ02_RS02985	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS02990	COG0840	transmembrane signaling receptor activity
LGQ02_RS02995	COG0840	transmembrane signaling receptor activity
LGQ02_RS03000	COG4129	membrane
LGQ02_RS03025	COG0778	Nitroreductase
LGQ02_RS03035	COG0714	Associated with various cellular activities
LGQ02_RS03040	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
LGQ02_RS03045	COG1305	Transglutaminase-like
LGQ02_RS03050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGQ02_RS03050	COG0519	Catalyzes the synthesis of GMP from XMP
LGQ02_RS03055	COG2252	PERMEase
LGQ02_RS03060	COG3424	synthase
LGQ02_RS03065	COG1755	Isoprenylcysteine carboxyl methyltransferase
LGQ02_RS03070	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
LGQ02_RS03080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGQ02_RS03085	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGQ02_RS03090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGQ02_RS03095	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LGQ02_RS03100	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGQ02_RS03105	COG0047	phosphoribosylformylglycinamidine synthase activity
LGQ02_RS03110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGQ02_RS03115	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGQ02_RS03120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGQ02_RS03125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGQ02_RS03135	COG0151	Belongs to the GarS family
LGQ02_RS03145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LGQ02_RS03150	COG1470	cell adhesion involved in biofilm formation
LGQ02_RS03155	COG4496	protein, YerC YecD
LGQ02_RS03165	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LGQ02_RS03170	COG0210	DNA helicase
LGQ02_RS03175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGQ02_RS03180	COG4851	CamS sex pheromone cAM373 precursor
LGQ02_RS03185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGQ02_RS03195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGQ02_RS03200	COG0154	amidase activity
LGQ02_RS03205	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGQ02_RS03215	COG0456	acetyltransferase
LGQ02_RS03225	COG0154	amidase activity
LGQ02_RS03255	COG1597	lipid kinase activity
LGQ02_RS03265	COG1131	(ABC) transporter
LGQ02_RS03270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LGQ02_RS03275	COG2311	Membrane
LGQ02_RS03290	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LGQ02_RS03310	COG1295	ribonuclease BN
LGQ02_RS03320	COG0003	Pfam Anion-transporting ATPase
LGQ02_RS03330	COG1966	Carbon starvation protein
LGQ02_RS03340	COG3012	SEC-C Motif Domain Protein
LGQ02_RS03345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGQ02_RS03350	COG0667	Aldo Keto reductase
LGQ02_RS03355	COG0667	Aldo Keto reductase
LGQ02_RS03370	COG1175	transmembrane transport
LGQ02_RS03375	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS03380	COG5578	integral membrane protein
LGQ02_RS03395	COG1940	carbohydrate kinase activity
LGQ02_RS03405	COG1486	melibiose metabolic process
LGQ02_RS03410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGQ02_RS03415	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGQ02_RS03445	COG0531	amino acid
LGQ02_RS03455	COG0697	spore germination
LGQ02_RS03460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGQ02_RS03465	COG0765	amino acid transport
LGQ02_RS03470	COG1126	abc transporter atp-binding protein
LGQ02_RS03475	COG1609	Transcriptional regulator
LGQ02_RS03480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGQ02_RS03490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGQ02_RS03495	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
LGQ02_RS03500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LGQ02_RS03510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LGQ02_RS03515	COG1063	alcohol dehydrogenase
LGQ02_RS03520	COG0800	Aldolase
LGQ02_RS03525	COG1312	Catalyzes the dehydration of D-mannonate
LGQ02_RS03530	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS03545	COG1757	Na H antiporter
LGQ02_RS03570	COG0387	Pfam Sodium calcium exchanger
LGQ02_RS03575	COG2153	protein acetylation
LGQ02_RS03580	COG2153	protein acetylation
LGQ02_RS03585	COG0584	glycerophosphoryl diester phosphodiesterase
LGQ02_RS03595	COG0739	heme binding
LGQ02_RS03595	COG0741	lytic transglycosylase activity
LGQ02_RS03595	COG1196	nuclear chromosome segregation
LGQ02_RS03605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS03625	COG1757	Na H antiporter
LGQ02_RS03630	COG2362	D-Aminopeptidase
LGQ02_RS03635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS03645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGQ02_RS03655	COG1061	Type III restriction enzyme res subunit
LGQ02_RS03670	COG0737	Belongs to the 5'-nucleotidase family
LGQ02_RS03680	COG4989	oxidoreductase activity
LGQ02_RS03685	COG1609	Transcriptional regulator
LGQ02_RS03695	COG1175	transmembrane transport
LGQ02_RS03700	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS03705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGQ02_RS03710	COG1621	beta-fructofuranosidase activity
LGQ02_RS03715	COG5578	integral membrane protein
LGQ02_RS03720	COG0154	amidase activity
LGQ02_RS03730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGQ02_RS03735	COG2323	membrane
LGQ02_RS03740	COG0038	chloride channel
LGQ02_RS03755	COG0300	oxidoreductase activity
LGQ02_RS03765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS03780	COG0561	phosphatase activity
LGQ02_RS03790	COG0516	GMP reductase activity
LGQ02_RS03800	COG1164	Oligoendopeptidase f
LGQ02_RS03805	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LGQ02_RS03810	COG1116	anion transmembrane transporter activity
LGQ02_RS03815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGQ02_RS03820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGQ02_RS03850	COG1609	Transcriptional regulator
LGQ02_RS03855	COG0366	Alpha amylase catalytic
LGQ02_RS03865	COG0501	Belongs to the peptidase M48B family
LGQ02_RS03920	COG1271	oxidase subunit
LGQ02_RS03925	COG1294	oxidase, subunit
LGQ02_RS03955	COG1404	Belongs to the peptidase S8 family
LGQ02_RS03970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGQ02_RS03980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LGQ02_RS03985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGQ02_RS03990	COG0720	synthase
LGQ02_RS03995	COG0602	queuosine metabolic process
LGQ02_RS04000	COG0840	transmembrane signaling receptor activity
LGQ02_RS04025	COG1132	(ABC) transporter
LGQ02_RS04030	COG1132	(ABC) transporter
LGQ02_RS04035	COG0295	cytidine deaminase activity
LGQ02_RS04040	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LGQ02_RS04045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGQ02_RS04050	COG2390	Transcriptional regulator
LGQ02_RS04070	COG3300	MHYT domain
LGQ02_RS04070	COG5001	Diguanylate cyclase
LGQ02_RS04075	COG1231	oxidoreductase activity
LGQ02_RS04140	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LGQ02_RS04155	COG0346	lactoylglutathione lyase activity
LGQ02_RS04170	COG2011	ABC-type metal ion transport system permease component
LGQ02_RS04175	COG1464	Belongs to the NlpA lipoprotein family
LGQ02_RS04195	COG0400	carboxylic ester hydrolase activity
LGQ02_RS04200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGQ02_RS04205	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LGQ02_RS04210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LGQ02_RS04215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGQ02_RS04250	COG0488	(ABC) transporter
LGQ02_RS04265	COG0513	Belongs to the DEAD box helicase family
LGQ02_RS04270	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGQ02_RS04290	COG0488	(ABC) transporter
LGQ02_RS04320	COG0628	permease
LGQ02_RS04330	COG1757	Na H antiporter
LGQ02_RS04335	COG1077	Cell shape determining protein MreB Mrl
LGQ02_RS04340	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS04345	COG2258	MOSC domain
LGQ02_RS04355	COG4145	pantothenate transmembrane transporter activity
LGQ02_RS04370	COG0010	Belongs to the arginase family
LGQ02_RS04375	COG1228	amidohydrolase
LGQ02_RS04380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGQ02_RS04400	COG2199	diguanylate cyclase activity
LGQ02_RS04420	COG0534	Mate efflux family protein
LGQ02_RS04425	COG1994	Peptidase M50
LGQ02_RS04430	COG1403	HNH endonuclease
LGQ02_RS04435	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS04445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LGQ02_RS04455	COG0415	Belongs to the DNA photolyase family
LGQ02_RS04470	COG0312	modulator of DNA gyrase
LGQ02_RS04475	COG0312	modulator of DNA gyrase
LGQ02_RS04485	COG1254	Belongs to the acylphosphatase family
LGQ02_RS04490	COG0204	Acyl-transferase
LGQ02_RS04520	COG1131	(ABC) transporter
LGQ02_RS04550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS04565	COG0477	Major facilitator Superfamily
LGQ02_RS04575	COG0534	Mate efflux family protein
LGQ02_RS04595	COG0535	radical SAM domain protein
LGQ02_RS04610	COG0406	alpha-ribazole phosphatase activity
LGQ02_RS04615	COG2346	COG2346, Truncated hemoglobins
LGQ02_RS04635	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LGQ02_RS04640	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGQ02_RS04645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGQ02_RS04655	COG1876	peptidase activity
LGQ02_RS04670	COG0473	3-isopropylmalate dehydrogenase activity
LGQ02_RS04675	COG5001	Diguanylate cyclase
LGQ02_RS04680	COG2514	catechol 2,3-dioxygenase activity
LGQ02_RS04685	COG0737	Belongs to the 5'-nucleotidase family
LGQ02_RS04690	COG2884	Cell division ATP-binding protein ftsE
LGQ02_RS04715	COG0366	Alpha amylase catalytic
LGQ02_RS04720	COG2188	Transcriptional regulator
LGQ02_RS04745	COG1090	epimerase
LGQ02_RS04750	COG2137	regulation of response to DNA damage stimulus
LGQ02_RS04755	COG1620	l-lactate permease
LGQ02_RS04780	COG1988	membrane-bound metal-dependent
LGQ02_RS04790	COG1194	a g-specific adenine glycosylase
LGQ02_RS04795	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS04805	COG2059	Chromate
LGQ02_RS04810	COG2059	Chromate
LGQ02_RS04815	COG0604	alcohol dehydrogenase
LGQ02_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS04840	COG3557	Belongs to the UPF0374 family
LGQ02_RS04845	COG1132	(ABC) transporter
LGQ02_RS04850	COG4129	membrane
LGQ02_RS04855	COG0067	glutamate synthase
LGQ02_RS04855	COG0069	glutamate synthase activity
LGQ02_RS04855	COG0070	glutamate synthase
LGQ02_RS04860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGQ02_RS04865	COG4555	ABC transporter
LGQ02_RS04885	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGQ02_RS04945	COG3870	Protein conserved in bacteria
LGQ02_RS04950	COG0735	belongs to the Fur family
LGQ02_RS05055	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LGQ02_RS05065	COG0726	polysaccharide deacetylase
LGQ02_RS05070	COG0004	ammonium transporteR
LGQ02_RS05075	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LGQ02_RS05095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGQ02_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS05125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGQ02_RS05145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGQ02_RS05165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGQ02_RS05170	COG2766	serine protein kinase
LGQ02_RS05180	COG2718	Belongs to the UPF0229 family
LGQ02_RS05220	COG2031	fatty acid transporter
LGQ02_RS05235	COG3546	catalase activity
LGQ02_RS05240	COG5002	protein histidine kinase activity
LGQ02_RS05245	COG3237	CsbD-like
LGQ02_RS05250	COG3192	ethanolamine utilization protein
LGQ02_RS05265	COG2201	protein-glutamate methylesterase activity
LGQ02_RS05270	COG1744	ABC transporter substrate-binding protein PnrA-like
LGQ02_RS05275	COG3845	ABC transporter
LGQ02_RS05280	COG4603	Belongs to the binding-protein-dependent transport system permease family
LGQ02_RS05285	COG1079	Belongs to the binding-protein-dependent transport system permease family
LGQ02_RS05295	COG3153	acetyltransferase
LGQ02_RS05295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGQ02_RS05300	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LGQ02_RS05310	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGQ02_RS05320	COG0697	spore germination
LGQ02_RS05340	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LGQ02_RS05355	COG4149	molybdate abc transporter
LGQ02_RS05360	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGQ02_RS05370	COG2719	SpoVR family
LGQ02_RS05375	COG1522	sequence-specific DNA binding
LGQ02_RS05380	COG0569	domain protein
LGQ02_RS05385	COG3546	catalase activity
LGQ02_RS05390	COG1227	inorganic diphosphatase activity
LGQ02_RS05395	COG1363	Peptidase, m42
LGQ02_RS05415	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGQ02_RS05420	COG0523	cobalamin synthesis protein
LGQ02_RS05430	COG0717	Belongs to the dCTP deaminase family
LGQ02_RS05435	COG0523	cobalamin synthesis protein
LGQ02_RS05440	COG0822	iron-sulfur transferase activity
LGQ02_RS05455	COG1469	GTP cyclohydrolase I activity
LGQ02_RS05460	COG0701	Predicted permease
LGQ02_RS05490	COG1178	ABC-type Fe3 transport system permease component
LGQ02_RS05515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGQ02_RS05525	COG4608	Belongs to the ABC transporter superfamily
LGQ02_RS05530	COG0444	Belongs to the ABC transporter superfamily
LGQ02_RS05535	COG0601	transmembrane transport
LGQ02_RS05540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGQ02_RS05555	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGQ02_RS05565	COG3583	domain protein
LGQ02_RS05565	COG3584	3D domain protein
LGQ02_RS05580	COG0024	Methionine aminopeptidase
LGQ02_RS05585	COG2323	membrane
LGQ02_RS05595	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS05610	COG1794	racemase activity, acting on amino acids and derivatives
LGQ02_RS05630	COG0789	Transcriptional regulator
LGQ02_RS05635	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS05645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGQ02_RS05655	COG1533	DNA photolyase activity
LGQ02_RS05670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGQ02_RS05675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGQ02_RS05675	COG1263	PTS System
LGQ02_RS05690	COG1131	(ABC) transporter
LGQ02_RS05695	COG1725	Transcriptional regulator
LGQ02_RS05710	COG3437	response regulator, receiver
LGQ02_RS05720	COG0667	Aldo Keto reductase
LGQ02_RS05775	COG1595	DNA-templated transcription, initiation
LGQ02_RS05780	COG1132	(ABC) transporter
LGQ02_RS05785	COG1132	(ABC) transporter
LGQ02_RS05790	COG0702	epimerase
LGQ02_RS05800	COG1827	regulation of RNA biosynthetic process
LGQ02_RS05805	COG1104	cysteine desulfurase activity
LGQ02_RS05810	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGQ02_RS05815	COG0157	Belongs to the NadC ModD family
LGQ02_RS05820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGQ02_RS05825	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS05830	COG0439	Biotin carboxylase
LGQ02_RS05835	COG0511	ligase activity, forming carbon-carbon bonds
LGQ02_RS05840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LGQ02_RS05845	COG1024	Enoyl-CoA hydratase
LGQ02_RS05850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LGQ02_RS05855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGQ02_RS05860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGQ02_RS05875	COG3842	ATPase activity
LGQ02_RS05880	COG2508	Transcriptional regulator
LGQ02_RS05900	COG0189	ligase activity
LGQ02_RS05915	COG4399	Belongs to the UPF0754 family
LGQ02_RS05920	COG3679	Belongs to the UPF0342 family
LGQ02_RS05925	COG0561	phosphatase activity
LGQ02_RS05935	COG0318	PFAM AMP-dependent synthetase and ligase
LGQ02_RS05940	COG4221	oxidoreductase activity
LGQ02_RS05985	COG4717	serine-type aminopeptidase activity
LGQ02_RS05990	COG1510	regulation of RNA biosynthetic process
LGQ02_RS05995	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS06000	COG2770	Histidine kinase
LGQ02_RS06000	COG2205	protein histidine kinase activity
LGQ02_RS06005	COG3481	metal-dependent phosphohydrolase, HD sub domain
LGQ02_RS06025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGQ02_RS06055	COG1846	Transcriptional regulator
LGQ02_RS06060	COG0537	adenosine 5'-monophosphoramidase activity
LGQ02_RS06070	COG1131	(ABC) transporter
LGQ02_RS06075	COG4473	ABC transporter
LGQ02_RS06085	COG1473	amidohydrolase
LGQ02_RS06090	COG0785	Cytochrome C biogenesis protein
LGQ02_RS06095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGQ02_RS06105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGQ02_RS06110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGQ02_RS06115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGQ02_RS06120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LGQ02_RS06125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGQ02_RS06135	COG3852	Histidine kinase
LGQ02_RS06140	COG3290	protein histidine kinase activity
LGQ02_RS06145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGQ02_RS06155	COG4492	Belongs to the UPF0735 family
LGQ02_RS06160	COG0077	Prephenate dehydratase
LGQ02_RS06175	COG0217	transcriptional regulatory protein
LGQ02_RS06185	COG0632	four-way junction helicase activity
LGQ02_RS06200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LGQ02_RS06205	COG0343	queuine tRNA-ribosyltransferase activity
LGQ02_RS06210	COG1862	Preprotein translocase
LGQ02_RS06220	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGQ02_RS06225	COG2323	membrane
LGQ02_RS06230	COG2244	polysaccharide biosynthetic process
LGQ02_RS06245	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGQ02_RS06245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGQ02_RS06250	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGQ02_RS06250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGQ02_RS06255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGQ02_RS06260	COG5416	Lipopolysaccharide assembly protein A domain
LGQ02_RS06265	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGQ02_RS06265	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LGQ02_RS06270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGQ02_RS06275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGQ02_RS06280	COG1490	D-aminoacyl-tRNA deacylase activity
LGQ02_RS06290	COG0124	histidyl-tRNA synthetase
LGQ02_RS06295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGQ02_RS06305	COG0247	lactate metabolic process
LGQ02_RS06310	COG1139	Iron-sulfur cluster binding protein
LGQ02_RS06315	COG1556	Lactate utilization protein
LGQ02_RS06320	COG3344	reverse transcriptase
LGQ02_RS06330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGQ02_RS06335	COG2364	Membrane
LGQ02_RS06340	COG1959	2 iron, 2 sulfur cluster binding
LGQ02_RS06345	COG1104	cysteine desulfurase activity
LGQ02_RS06350	COG0482	sulfurtransferase activity
LGQ02_RS06360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGQ02_RS06380	COG0628	permease
LGQ02_RS06385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGQ02_RS06390	COG4472	Bacterial protein of unknown function (DUF965)
LGQ02_RS06400	COG3906	Belongs to the UPF0473 family
LGQ02_RS06410	COG4122	O-methyltransferase activity
LGQ02_RS06415	COG0826	peptidase U32
LGQ02_RS06420	COG0826	peptidase U32
LGQ02_RS06425	COG0572	uridine kinase
LGQ02_RS06430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGQ02_RS06435	COG1725	Transcriptional regulator
LGQ02_RS06440	COG1131	(ABC) transporter
LGQ02_RS06465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGQ02_RS06475	COG2814	Major facilitator Superfamily
LGQ02_RS06480	COG0494	nUDIX hydrolase
LGQ02_RS06485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGQ02_RS06490	COG4946	Tricorn protease homolog
LGQ02_RS06490	COG1506	peptidase
LGQ02_RS06490	COG0823	Involved in the tonB-independent uptake of proteins
LGQ02_RS06500	COG0366	Alpha amylase catalytic
LGQ02_RS06510	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGQ02_RS06540	COG1595	DNA-templated transcription, initiation
LGQ02_RS06575	COG4876	unkown
LGQ02_RS06580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGQ02_RS06615	COG1335	isochorismatase
LGQ02_RS06620	COG0095	Lipoate-protein ligase
LGQ02_RS06630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGQ02_RS06635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS06640	COG0450	alkyl hydroperoxide reductase
LGQ02_RS06645	COG0617	tRNA 3'-terminal CCA addition
LGQ02_RS06645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LGQ02_RS06645	COG3620	sequence-specific DNA binding
LGQ02_RS06650	COG1183	phosphatidylcholine synthase activity
LGQ02_RS06655	COG0688	phosphatidylethanolamine metabolic process
LGQ02_RS06660	COG3835	regulator
LGQ02_RS06665	COG0277	FAD linked oxidase domain protein
LGQ02_RS06670	COG0247	lactate metabolic process
LGQ02_RS06695	COG1484	DNA-dependent DNA replication
LGQ02_RS06710	COG1320	monovalent cation:proton antiporter activity
LGQ02_RS06715	COG2212	antiporter activity
LGQ02_RS06720	COG1863	multisubunit Na H antiporter MnhE subunit
LGQ02_RS06725	COG0651	ATP synthesis coupled electron transport
LGQ02_RS06730	COG1006	Multisubunit Na H antiporter MnhC subunit
LGQ02_RS06735	COG2111	Na H antiporter
LGQ02_RS06740	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGQ02_RS06740	COG2111	Na H antiporter
LGQ02_RS06755	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LGQ02_RS06760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LGQ02_RS06770	COG1534	Rna-binding protein
LGQ02_RS06775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGQ02_RS06780	COG1713	HD superfamily hydrolase involved in NAD metabolism
LGQ02_RS06785	COG0799	negative regulation of ribosome biogenesis
LGQ02_RS06790	COG2226	methyltransferase
LGQ02_RS06795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGQ02_RS06800	COG1596	polysaccharide export
LGQ02_RS06800	COG1555	photosystem II stabilization
LGQ02_RS06805	COG2131	deaminase
LGQ02_RS06815	COG1522	sequence-specific DNA binding
LGQ02_RS06850	COG0658	competence protein
LGQ02_RS06850	COG2333	competence protein COMEC
LGQ02_RS06860	COG1466	dna polymerase III delta subunit
LGQ02_RS06865	COG0268	Binds directly to 16S ribosomal RNA
LGQ02_RS06875	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGQ02_RS06885	COG0481	GTPase activity
LGQ02_RS06890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGQ02_RS06895	COG1420	regulation of RNA biosynthetic process
LGQ02_RS06900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGQ02_RS06905	COG0443	Heat shock 70 kDa protein
LGQ02_RS06910	COG0484	heat shock protein binding
LGQ02_RS06915	COG2264	protein methyltransferase activity
LGQ02_RS06920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGQ02_RS06925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGQ02_RS06930	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LGQ02_RS06935	COG1283	sodium-dependent phosphate transmembrane transporter activity
LGQ02_RS06940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGQ02_RS06945	COG1610	YqeY-like protein
LGQ02_RS06950	COG1030	water channel activity
LGQ02_RS06955	COG4864	UPF0365 protein
LGQ02_RS06985	COG1702	phosphate starvation-inducible protein PhoH
LGQ02_RS06990	COG1480	7TM receptor with intracellular HD hydrolase
LGQ02_RS07000	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGQ02_RS07015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGQ02_RS07025	COG1381	Involved in DNA repair and RecF pathway recombination
LGQ02_RS07030	COG0752	glycyl-tRNA synthetase alpha subunit
LGQ02_RS07035	COG0751	glycine-tRNA ligase activity
LGQ02_RS07040	COG0517	IMP dehydrogenase activity
LGQ02_RS07045	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGQ02_RS07050	COG1671	Belongs to the UPF0178 family
LGQ02_RS07055	COG0358	DNA primase activity
LGQ02_RS07060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGQ02_RS07070	COG0584	glycerophosphoryl diester phosphodiesterase
LGQ02_RS07075	COG2010	Cytochrome c
LGQ02_RS07080	COG2384	SAM-dependent methyltransferase
LGQ02_RS07085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGQ02_RS07090	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGQ02_RS07095	COG1329	Transcriptional regulator
LGQ02_RS07105	COG0513	Belongs to the DEAD box helicase family
LGQ02_RS07110	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGQ02_RS07120	COG1121	(ABC) transporter
LGQ02_RS07125	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGQ02_RS07135	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGQ02_RS07145	COG1121	(ABC) transporter
LGQ02_RS07150	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGQ02_RS07155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGQ02_RS07160	COG0735	belongs to the Fur family
LGQ02_RS07165	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
LGQ02_RS07170	COG4709	membrane
LGQ02_RS07175	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LGQ02_RS07180	COG1388	LysM domain
LGQ02_RS07185	COG2814	Major facilitator Superfamily
LGQ02_RS07190	COG4086	secreted protein
LGQ02_RS07205	COG1283	sodium-dependent phosphate transmembrane transporter activity
LGQ02_RS07225	COG4918	Iron-sulphur cluster biosynthesis
LGQ02_RS07230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGQ02_RS07235	COG5278	phosphoserine phosphatase activity
LGQ02_RS07235	COG0840	transmembrane signaling receptor activity
LGQ02_RS07240	COG0477	Major facilitator Superfamily
LGQ02_RS07255	COG0768	penicillin binding
LGQ02_RS07275	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGQ02_RS07280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGQ02_RS07290	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGQ02_RS07295	COG0039	L-malate dehydrogenase activity
LGQ02_RS07310	COG0457	Tetratricopeptide repeat
LGQ02_RS07310	COG0705	Rhomboid family
LGQ02_RS07320	COG0697	spore germination
LGQ02_RS07325	COG5506	Protein of unknown function (DUF1694)
LGQ02_RS07335	COG4483	Protein conserved in bacteria
LGQ02_RS07340	COG1940	carbohydrate kinase activity
LGQ02_RS07355	COG0011	TIGRFAM Protein of
LGQ02_RS07365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS07385	COG4980	gas vesicle protein
LGQ02_RS07395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGQ02_RS07400	COG1459	type II secretion system
LGQ02_RS07405	COG4537	Required for transformation and DNA binding
LGQ02_RS07435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGQ02_RS07450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGQ02_RS07455	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGQ02_RS07460	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGQ02_RS07465	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGQ02_RS07475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS07480	COG0095	Lipoate-protein ligase
LGQ02_RS07490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGQ02_RS07505	COG1321	iron dependent repressor
LGQ02_RS07510	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGQ02_RS07530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LGQ02_RS07535	COG0006	proline dipeptidase activity
LGQ02_RS07540	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGQ02_RS07545	COG3854	ATPases associated with a variety of cellular activities
LGQ02_RS07590	COG0511	ligase activity, forming carbon-carbon bonds
LGQ02_RS07595	COG0439	Biotin carboxylase
LGQ02_RS07600	COG1302	Protein conserved in bacteria
LGQ02_RS07605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGQ02_RS07610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGQ02_RS07615	COG1570	exodeoxyribonuclease VII activity
LGQ02_RS07620	COG1722	exodeoxyribonuclease VII activity
LGQ02_RS07625	COG0142	geranyltranstransferase activity
LGQ02_RS07635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGQ02_RS07645	COG1438	arginine binding
LGQ02_RS07650	COG0497	DNA recombination
LGQ02_RS07655	COG0750	zinc metalloprotease
LGQ02_RS07660	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS07670	COG1215	transferase activity, transferring glycosyl groups
LGQ02_RS07685	COG3829	transcription factor binding
LGQ02_RS07685	COG3290	protein histidine kinase activity
LGQ02_RS07690	COG0280	phosphate acetyltransferase
LGQ02_RS07700	COG3426	butyrate kinase activity
LGQ02_RS07705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGQ02_RS07710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LGQ02_RS07715	COG0022	dehydrogenase e1 component
LGQ02_RS07720	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGQ02_RS07745	COG4129	membrane
LGQ02_RS07750	COG1376	ErfK ybiS ycfS ynhG family protein
LGQ02_RS07760	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LGQ02_RS07760	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LGQ02_RS07765	COG0346	lactoylglutathione lyase activity
LGQ02_RS07770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LGQ02_RS07775	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGQ02_RS07790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGQ02_RS07800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGQ02_RS07820	COG1728	Protein conserved in bacteria
LGQ02_RS07835	COG1902	pentaerythritol trinitrate reductase activity
LGQ02_RS07840	COG0517	IMP dehydrogenase activity
LGQ02_RS07850	COG4187	Peptidase family M20/M25/M40
LGQ02_RS07860	COG2861	carbohydrate metabolic process
LGQ02_RS07865	COG0789	Transcriptional regulator
LGQ02_RS07875	COG1233	COG1233 Phytoene dehydrogenase and related
LGQ02_RS07880	COG0300	oxidoreductase activity
LGQ02_RS07885	COG1131	(ABC) transporter
LGQ02_RS07890	COG0842	Transport permease protein
LGQ02_RS07895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGQ02_RS07910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGQ02_RS07915	COG0460	homoserine dehydrogenase
LGQ02_RS07920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LGQ02_RS07930	COG0367	asparagine synthase
LGQ02_RS07935	COG2414	aldehyde ferredoxin oxidoreductase
LGQ02_RS07950	COG0406	alpha-ribazole phosphatase activity
LGQ02_RS07970	COG0561	phosphatase activity
LGQ02_RS07985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGQ02_RS08000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGQ02_RS08005	COG2190	(PTS) system
LGQ02_RS08020	COG0701	Predicted permease
LGQ02_RS08025	COG1968	undecaprenyl-diphosphatase activity
LGQ02_RS08030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS08035	COG0667	Aldo Keto reductase
LGQ02_RS08050	COG0494	nUDIX hydrolase
LGQ02_RS08055	COG1379	DNA repair
LGQ02_RS08060	COG1300	Membrane
LGQ02_RS08065	COG0735	belongs to the Fur family
LGQ02_RS08075	COG4974	Belongs to the 'phage' integrase family
LGQ02_RS08100	COG1686	Belongs to the peptidase S11 family
LGQ02_RS08105	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS08110	COG2172	sigma factor antagonist activity
LGQ02_RS08135	COG0697	spore germination
LGQ02_RS08140	COG0019	diaminopimelate decarboxylase activity
LGQ02_RS08145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGQ02_RS08150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGQ02_RS08150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGQ02_RS08155	COG0307	riboflavin synthase, alpha
LGQ02_RS08160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGQ02_RS08160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGQ02_RS08165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGQ02_RS08170	COG0456	acetyltransferase
LGQ02_RS08175	COG1547	Domain of unknown function (DUF309)
LGQ02_RS08180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LGQ02_RS08185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LGQ02_RS08195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGQ02_RS08200	COG2323	membrane
LGQ02_RS08220	COG2323	membrane
LGQ02_RS08225	COG1686	Belongs to the peptidase S11 family
LGQ02_RS08230	COG2715	membrane protein required for spore maturation
LGQ02_RS08235	COG0700	Nucleoside recognition
LGQ02_RS08240	COG1187	pseudouridine synthase activity
LGQ02_RS08245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS08250	COG1333	cytochrome c biogenesis protein
LGQ02_RS08255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGQ02_RS08260	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS08265	COG5002	protein histidine kinase activity
LGQ02_RS08270	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGQ02_RS08275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGQ02_RS08280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGQ02_RS08285	COG1120	ATPase activity
LGQ02_RS08290	COG2096	Adenosyltransferase
LGQ02_RS08305	COG2186	Transcriptional regulator
LGQ02_RS08315	COG1141	Ferredoxin
LGQ02_RS08320	COG4955	Helix-turn-helix domain
LGQ02_RS08325	COG0514	ATP-dependent DNA helicase (RecQ)
LGQ02_RS08330	COG1266	CAAX protease self-immunity
LGQ02_RS08365	COG4862	establishment of competence for transformation
LGQ02_RS08370	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LGQ02_RS08380	COG0492	ferredoxin-NADP+ reductase activity
LGQ02_RS08385	COG0252	asparaginase activity
LGQ02_RS08390	COG2339	peptidase activity
LGQ02_RS08400	COG3773	Cell wall hydrolase
LGQ02_RS08400	COG3409	Peptidoglycan-binding domain 1 protein
LGQ02_RS08405	COG2959	enzyme of heme biosynthesis
LGQ02_RS08415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LGQ02_RS08420	COG0204	Acyl-transferase
LGQ02_RS08425	COG0539	negative regulation of cytoplasmic translation
LGQ02_RS08445	COG1160	GTP binding
LGQ02_RS08450	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGQ02_RS08455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGQ02_RS08475	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LGQ02_RS08485	COG2409	Drug exporters of the RND superfamily
LGQ02_RS08500	COG0302	gtp cyclohydrolase
LGQ02_RS08510	COG0142	geranyltranstransferase activity
LGQ02_RS08515	COG2226	methyltransferase
LGQ02_RS08520	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LGQ02_RS08525	COG0163	prenyltransferase activity
LGQ02_RS08530	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LGQ02_RS08535	COG0142	geranyltranstransferase activity
LGQ02_RS08540	COG0105	UTP biosynthetic process
LGQ02_RS08545	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGQ02_RS08550	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LGQ02_RS08555	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LGQ02_RS08560	COG4401	Chorismate mutase type I
LGQ02_RS08565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGQ02_RS08570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGQ02_RS08575	COG0134	indole-3-glycerol-phosphate synthase activity
LGQ02_RS08580	COG0133	tryptophan synthase activity
LGQ02_RS08585	COG0159	tryptophan synthase activity
LGQ02_RS08590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGQ02_RS08595	COG0287	Prephenate dehydrogenase
LGQ02_RS08600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGQ02_RS08610	COG0457	Tetratricopeptide repeat
LGQ02_RS08620	COG5582	Belongs to the UPF0302 family
LGQ02_RS08630	COG0723	plastoquinol--plastocyanin reductase activity
LGQ02_RS08635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LGQ02_RS08640	COG2010	Cytochrome c
LGQ02_RS08640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LGQ02_RS08645	COG4347	Protein of unknown function (DUF1405)
LGQ02_RS08655	COG2738	Putative neutral zinc metallopeptidase
LGQ02_RS08660	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS08665	COG1694	Mazg nucleotide pyrophosphohydrolase
LGQ02_RS08670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LGQ02_RS08675	COG1803	Methylglyoxal synthase
LGQ02_RS08680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LGQ02_RS08685	COG0438	transferase activity, transferring glycosyl groups
LGQ02_RS08700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGQ02_RS08705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGQ02_RS08710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGQ02_RS08720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGQ02_RS08720	COG1199	ATP-dependent helicase activity
LGQ02_RS08725	COG0658	competence protein
LGQ02_RS08725	COG2333	competence protein COMEC
LGQ02_RS08730	COG0402	S-adenosylhomocysteine deaminase activity
LGQ02_RS08750	COG0436	Aminotransferase
LGQ02_RS08755	COG0017	Asparaginyl-tRNA synthetase
LGQ02_RS08760	COG3935	DnaD domain protein
LGQ02_RS08765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGQ02_RS08775	COG4499	WXG100 protein secretion system (Wss), protein YukC
LGQ02_RS08775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGQ02_RS08780	COG3331	DNA recombination
LGQ02_RS08790	COG0789	Transcriptional regulator
LGQ02_RS08805	COG2860	membrane
LGQ02_RS08820	COG0488	(ABC) transporter
LGQ02_RS08830	COG0406	alpha-ribazole phosphatase activity
LGQ02_RS08835	COG1335	isochorismatase
LGQ02_RS08845	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
LGQ02_RS08850	COG2391	methyltransferase activity
LGQ02_RS08875	COG1413	lyase activity
LGQ02_RS08885	COG3402	PFAM membrane-flanked domain
LGQ02_RS08890	COG3428	Bacterial PH domain
LGQ02_RS08900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS08905	COG1191	sigma factor activity
LGQ02_RS08945	COG1953	Uracil, thiamine, allantoin
LGQ02_RS08955	COG1597	lipid kinase activity
LGQ02_RS08960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGQ02_RS08965	COG0805	protein transport
LGQ02_RS09035	COG1428	Deoxynucleoside kinase
LGQ02_RS09040	COG1428	Deoxynucleoside kinase
LGQ02_RS09070	COG2814	Major facilitator Superfamily
LGQ02_RS09080	COG2322	membrane
LGQ02_RS09100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LGQ02_RS09105	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGQ02_RS09110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGQ02_RS09115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGQ02_RS09120	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS09155	COG1509	lysine 2,3-aminomutase activity
LGQ02_RS09160	COG3829	transcription factor binding
LGQ02_RS09165	COG3409	Peptidoglycan-binding domain 1 protein
LGQ02_RS09165	COG3773	Cell wall hydrolase
LGQ02_RS09170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGQ02_RS09180	COG0114	fumarate hydratase activity
LGQ02_RS09200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LGQ02_RS09205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGQ02_RS09210	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGQ02_RS09225	COG1686	Belongs to the peptidase S11 family
LGQ02_RS09240	COG0436	Aminotransferase
LGQ02_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS09250	COG2135	peptidase activity
LGQ02_RS09255	COG0567	Dehydrogenase, E1 component
LGQ02_RS09260	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGQ02_RS09295	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LGQ02_RS09345	COG1368	sulfuric ester hydrolase activity
LGQ02_RS09370	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LGQ02_RS09390	COG2124	cytochrome p450
LGQ02_RS09400	COG3243	poly(R)-hydroxyalkanoic acid synthase
LGQ02_RS09435	COG2223	nitrite transmembrane transporter activity
LGQ02_RS09440	COG0490	domain, Protein
LGQ02_RS09440	COG0471	metal ion transport
LGQ02_RS09460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGQ02_RS09485	COG0456	acetyltransferase
LGQ02_RS09490	COG3583	domain protein
LGQ02_RS09490	COG3584	3D domain protein
LGQ02_RS09520	COG2814	Major facilitator Superfamily
LGQ02_RS09655	COG0561	phosphatase activity
LGQ02_RS09670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGQ02_RS09670	COG3711	transcriptional antiterminator
LGQ02_RS09680	COG3730	PTS system glucitol sorbitol-specific
LGQ02_RS09685	COG3732	PTS system glucitol sorbitol-specific
LGQ02_RS09700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGQ02_RS09720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LGQ02_RS09730	COG4637	Psort location Cytoplasmic, score
LGQ02_RS09790	COG1401	restriction endodeoxyribonuclease activity
LGQ02_RS09810	COG0537	adenosine 5'-monophosphoramidase activity
LGQ02_RS09815	COG1061	Type III restriction enzyme res subunit
LGQ02_RS09840	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LGQ02_RS09850	COG3858	chitin binding
LGQ02_RS09855	COG1329	Transcriptional regulator
LGQ02_RS09905	COG0129	dihydroxy-acid dehydratase activity
LGQ02_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS09935	COG1472	Belongs to the glycosyl hydrolase 3 family
LGQ02_RS09955	COG0840	transmembrane signaling receptor activity
LGQ02_RS09960	COG1595	DNA-templated transcription, initiation
LGQ02_RS09980	COG2203	Gaf domain
LGQ02_RS09980	COG3706	GGDEF domain
LGQ02_RS09980	COG4251	negative regulation of phosphorylation
LGQ02_RS09980	COG5001	Diguanylate cyclase
LGQ02_RS10040	COG1278	Cold shock
LGQ02_RS10055	COG1278	Cold shock
LGQ02_RS10065	COG2267	carboxylic ester hydrolase activity
LGQ02_RS10075	COG2323	membrane
LGQ02_RS10095	COG1714	RDD family
LGQ02_RS10100	COG1858	cytochrome C peroxidase
LGQ02_RS10115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS10140	COG0561	phosphatase activity
LGQ02_RS10150	COG2211	Major facilitator Superfamily
LGQ02_RS10175	COG0519	Catalyzes the synthesis of GMP from XMP
LGQ02_RS10305	COG0202	RNA polymerase activity
LGQ02_RS10320	COG2066	Belongs to the glutaminase family
LGQ02_RS10340	COG2814	Major facilitator Superfamily
LGQ02_RS10380	COG0778	Nitroreductase
LGQ02_RS10385	COG0697	spore germination
LGQ02_RS10390	COG2502	aspartate--ammonia ligase
LGQ02_RS10395	COG1011	Hydrolase
LGQ02_RS10455	COG0494	nUDIX hydrolase
LGQ02_RS10480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGQ02_RS10495	COG0346	lactoylglutathione lyase activity
LGQ02_RS10500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGQ02_RS10510	COG0398	Pfam SNARE associated Golgi protein
LGQ02_RS10520	COG2962	Rard protein
LGQ02_RS10530	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LGQ02_RS10535	COG1074	ATP-dependent DNA helicase activity
LGQ02_RS10540	COG0420	3'-5' exonuclease activity
LGQ02_RS10545	COG0419	ATPase involved in DNA repair
LGQ02_RS10560	COG2814	Major facilitator Superfamily
LGQ02_RS10580	COG2359	stage V sporulation protein S
LGQ02_RS10585	COG0488	(ABC) transporter
LGQ02_RS10595	COG1164	Oligoendopeptidase f
LGQ02_RS10600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGQ02_RS10615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGQ02_RS10625	COG1309	transcriptional regulator
LGQ02_RS10635	COG2105	PFAM AIG2 family protein
LGQ02_RS10635	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
LGQ02_RS10640	COG0523	cobalamin synthesis protein
LGQ02_RS10655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGQ02_RS10660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGQ02_RS10670	COG1764	response to oxidative stress
LGQ02_RS10680	COG3871	stress protein (general stress protein 26)
LGQ02_RS10700	COG0346	lactoylglutathione lyase activity
LGQ02_RS10705	COG3942	CHAP domain
LGQ02_RS10705	COG1388	LysM domain
LGQ02_RS10710	COG1366	Belongs to the anti-sigma-factor antagonist family
LGQ02_RS10715	COG0431	NADPH-dependent FMN reductase
LGQ02_RS10720	COG2197	response regulator
LGQ02_RS10725	COG2203	Gaf domain
LGQ02_RS10725	COG4585	Histidine kinase
LGQ02_RS10730	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGQ02_RS10755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGQ02_RS10765	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LGQ02_RS10770	COG4294	response to UV
LGQ02_RS10775	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LGQ02_RS10790	COG1217	gtp-binding protein TYPA
LGQ02_RS10795	COG1278	Cold shock
LGQ02_RS10810	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LGQ02_RS10815	COG5522	Integral membrane protein (intg_mem_TP0381)
LGQ02_RS10835	COG4221	oxidoreductase activity
LGQ02_RS10845	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LGQ02_RS10850	COG0535	radical SAM domain protein
LGQ02_RS10865	COG2996	Protein conserved in bacteria
LGQ02_RS10870	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGQ02_RS10880	COG1376	ErfK ybiS ycfS ynhG family protein
LGQ02_RS10885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS10895	COG4191	Histidine kinase
LGQ02_RS10910	COG2340	Cysteine-rich secretory protein family
LGQ02_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS10920	COG1073	alpha beta
LGQ02_RS10925	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGQ02_RS10960	COG0791	NLP P60 protein
LGQ02_RS10965	COG3942	CHAP domain
LGQ02_RS10965	COG1388	LysM domain
LGQ02_RS10970	COG1054	Belongs to the UPF0176 family
LGQ02_RS10975	COG2508	Transcriptional regulator
LGQ02_RS10980	COG0006	proline dipeptidase activity
LGQ02_RS10995	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS11000	COG1388	LysM domain
LGQ02_RS11000	COG0791	NLP P60 protein
LGQ02_RS11035	COG2508	Transcriptional regulator
LGQ02_RS11040	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS11045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LGQ02_RS11060	COG2267	carboxylic ester hydrolase activity
LGQ02_RS11085	COG1834	amidinotransferase
LGQ02_RS11095	COG0243	molybdopterin cofactor binding
LGQ02_RS11105	COG1917	Cupin 2, conserved barrel domain protein
LGQ02_RS11110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGQ02_RS11115	COG0456	acetyltransferase
LGQ02_RS11120	COG2070	2-Nitropropane dioxygenase
LGQ02_RS11135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGQ02_RS11140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGQ02_RS11150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGQ02_RS11155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGQ02_RS11160	COG2362	D-Aminopeptidase
LGQ02_RS11165	COG1757	Na H antiporter
LGQ02_RS11175	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGQ02_RS11190	COG2244	polysaccharide biosynthetic process
LGQ02_RS11205	COG3858	chitin binding
LGQ02_RS11210	COG1404	Belongs to the peptidase S8 family
LGQ02_RS11215	COG1388	LysM domain
LGQ02_RS11215	COG0791	NLP P60 protein
LGQ02_RS11220	COG1388	LysM domain
LGQ02_RS11220	COG0791	NLP P60 protein
LGQ02_RS11230	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGQ02_RS11270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LGQ02_RS11275	COG0583	DNA-binding transcription factor activity
LGQ02_RS11280	COG2027	D-alanyl-D-alanine carboxypeptidase
LGQ02_RS11285	COG3300	MHYT domain
LGQ02_RS11285	COG5001	Diguanylate cyclase
LGQ02_RS11390	COG0537	adenosine 5'-monophosphoramidase activity
LGQ02_RS11405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGQ02_RS11420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGQ02_RS11425	COG0187	DNA topoisomerase II activity
LGQ02_RS11430	COG1832	CoA-binding protein
LGQ02_RS11440	COG1174	glycine betaine transport
LGQ02_RS11450	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LGQ02_RS11470	COG0116	Belongs to the methyltransferase superfamily
LGQ02_RS11480	COG0328	RNA-DNA hybrid ribonuclease activity
LGQ02_RS11485	COG3599	regulation of cell shape
LGQ02_RS11505	COG2871	sodium ion transport
LGQ02_RS11520	COG3359	exonuclease
LGQ02_RS11540	COG1111	helicase
LGQ02_RS11540	COG1205	dead DEAH box helicase
LGQ02_RS11595	COG3069	C4-dicarboxylate transmembrane transporter activity
LGQ02_RS11600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGQ02_RS11610	COG5001	Diguanylate cyclase
LGQ02_RS11610	COG3300	MHYT domain
LGQ02_RS11630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGQ02_RS11640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGQ02_RS11645	COG0686	Belongs to the AlaDH PNT family
LGQ02_RS11650	COG2508	Transcriptional regulator
LGQ02_RS11650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LGQ02_RS11655	COG1115	amino acid carrier protein
LGQ02_RS11670	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LGQ02_RS11710	COG1484	DNA-dependent DNA replication
LGQ02_RS11765	COG0535	radical SAM domain protein
LGQ02_RS11770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGQ02_RS11785	COG1376	ErfK ybiS ycfS ynhG family protein
LGQ02_RS11805	COG0693	protein deglycase activity
LGQ02_RS11810	COG0791	NLP P60 protein
LGQ02_RS11810	COG1388	LysM domain
LGQ02_RS11815	COG1418	mRNA catabolic process
LGQ02_RS11820	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGQ02_RS11825	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGQ02_RS11850	COG1131	(ABC) transporter
LGQ02_RS11855	COG1725	Transcriptional regulator
LGQ02_RS11860	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LGQ02_RS11865	COG1131	(ABC) transporter
LGQ02_RS11930	COG2814	Major facilitator Superfamily
LGQ02_RS11935	COG2200	EAL domain
LGQ02_RS11945	COG0613	PHP domain protein
LGQ02_RS11950	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGQ02_RS11965	COG0824	Thioesterase
LGQ02_RS11970	COG0464	growth
LGQ02_RS11985	COG0697	spore germination
LGQ02_RS11990	COG1388	LysM domain
LGQ02_RS11990	COG3858	chitin binding
LGQ02_RS11995	COG0398	Pfam SNARE associated Golgi protein
LGQ02_RS12015	COG2323	membrane
LGQ02_RS12025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGQ02_RS12045	COG1921	L-seryl-tRNASec selenium transferase activity
LGQ02_RS12055	COG0709	Synthesizes selenophosphate from selenide and ATP
LGQ02_RS12075	COG1595	DNA-templated transcription, initiation
LGQ02_RS12125	COG5609	conserved protein (DUF2294)
LGQ02_RS12130	COG2223	nitrite transmembrane transporter activity
LGQ02_RS12145	COG0762	integral membrane protein
LGQ02_RS12170	COG4846	Membrane protein involved in cytochrome C biogenesis
LGQ02_RS12185	COG1937	Protein conserved in bacteria
LGQ02_RS12195	COG1132	(ABC) transporter
LGQ02_RS12200	COG1132	(ABC) transporter
LGQ02_RS12205	COG3763	UPF0154 protein
LGQ02_RS12215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGQ02_RS12220	COG4224	UPF0291 protein
LGQ02_RS12225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGQ02_RS12230	COG1388	LysM domain
LGQ02_RS12235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGQ02_RS12245	COG0174	glutamine synthetase
LGQ02_RS12250	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LGQ02_RS12255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGQ02_RS12260	COG0464	growth
LGQ02_RS12270	COG1923	regulation of RNA biosynthetic process
LGQ02_RS12275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGQ02_RS12280	COG2136	Putative SAM-dependent methyltransferase
LGQ02_RS12280	COG2521	methyltransferase
LGQ02_RS12285	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGQ02_RS12290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGQ02_RS12305	COG4550	Control of competence regulator ComK, YlbF/YmcA
LGQ02_RS12310	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGQ02_RS12315	COG0156	8-amino-7-oxononanoate synthase activity
LGQ02_RS12320	COG1063	alcohol dehydrogenase
LGQ02_RS12330	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGQ02_RS12335	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGQ02_RS12335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGQ02_RS12340	COG2359	stage V sporulation protein S
LGQ02_RS12345	COG1692	metallophosphoesterase
LGQ02_RS12350	COG1418	mRNA catabolic process
LGQ02_RS12355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGQ02_RS12360	COG0513	Belongs to the DEAD box helicase family
LGQ02_RS12365	COG1058	Belongs to the CinA family
LGQ02_RS12365	COG1546	Belongs to the CinA family
LGQ02_RS12370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGQ02_RS12375	COG1426	Protein conserved in bacteria
LGQ02_RS12390	COG0300	oxidoreductase activity
LGQ02_RS12395	COG0612	Peptidase, M16
LGQ02_RS12400	COG0612	Peptidase, M16
LGQ02_RS12405	COG2188	Transcriptional regulator
LGQ02_RS12410	COG1674	ftsk spoiiie
LGQ02_RS12420	COG0740	serine-type endopeptidase activity
LGQ02_RS12430	COG0527	aspartate kinase activity
LGQ02_RS12435	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGQ02_RS12440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGQ02_RS12445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGQ02_RS12450	COG1873	PFAM PRC-barrel domain
LGQ02_RS12455	COG0612	Peptidase, M16
LGQ02_RS12460	COG0726	polysaccharide deacetylase
LGQ02_RS12465	COG1185	polyribonucleotide nucleotidyltransferase activity
LGQ02_RS12470	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LGQ02_RS12475	COG0196	riboflavin kinase activity
LGQ02_RS12480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LGQ02_RS12485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGQ02_RS12490	COG1550	Protein conserved in bacteria
LGQ02_RS12495	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LGQ02_RS12500	COG1358	cellular component organization or biogenesis
LGQ02_RS12505	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LGQ02_RS12510	COG0195	Participates in both transcription termination and antitermination
LGQ02_RS12515	COG0779	Required for maturation of 30S ribosomal subunits
LGQ02_RS12520	COG2176	DNA-directed DNA polymerase activity
LGQ02_RS12525	COG0442	prolyl-tRNA aminoacylation
LGQ02_RS12530	COG0750	zinc metalloprotease
LGQ02_RS12535	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LGQ02_RS12540	COG4589	Belongs to the CDS family
LGQ02_RS12545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LGQ02_RS12550	COG0233	cytoplasmic translational termination
LGQ02_RS12560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGQ02_RS12565	COG0052	Belongs to the universal ribosomal protein uS2 family
LGQ02_RS12585	COG1191	sigma factor activity
LGQ02_RS12595	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LGQ02_RS12600	COG1776	CheC inhibitor of MCP methylation
LGQ02_RS12605	COG0835	chemotaxis
LGQ02_RS12610	COG0643	Histidine kinase
LGQ02_RS12610	COG2198	Histidine kinase
LGQ02_RS12615	COG2201	protein-glutamate methylesterase activity
LGQ02_RS12620	COG0455	bacterial-type flagellum organization
LGQ02_RS12625	COG1419	protein localization to endoplasmic reticulum
LGQ02_RS12630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGQ02_RS12635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGQ02_RS12640	COG1684	flagellar biosynthetic protein fliR
LGQ02_RS12645	COG1987	bacterial-type flagellum assembly
LGQ02_RS12650	COG1338	Plays a role in the flagellum-specific transport system
LGQ02_RS12655	COG3190	flagellar
LGQ02_RS12660	COG2201	protein-glutamate methylesterase activity
LGQ02_RS12665	COG1776	CheC inhibitor of MCP methylation
LGQ02_RS12665	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGQ02_RS12670	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGQ02_RS12680	COG1582	Flagellar protein (FlbD)
LGQ02_RS12695	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LGQ02_RS12710	COG2882	bacterial-type flagellum organization
LGQ02_RS12715	COG1157	protein secretion by the type III secretion system
LGQ02_RS12720	COG1317	bacterial-type flagellum organization
LGQ02_RS12725	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGQ02_RS12730	COG1766	The M ring may be actively involved in energy transduction
LGQ02_RS12735	COG1677	Flagellar hook-basal body complex protein FliE
LGQ02_RS12740	COG1558	bacterial-type flagellum-dependent cell motility
LGQ02_RS12745	COG1815	bacterial-type flagellum-dependent cell motility
LGQ02_RS12750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LGQ02_RS12755	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGQ02_RS12760	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGQ02_RS12765	COG4974	Belongs to the 'phage' integrase family
LGQ02_RS12770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGQ02_RS12775	COG0758	DNA mediated transformation
LGQ02_RS12780	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGQ02_RS12785	COG0045	succinate-CoA ligase (ADP-forming) activity
LGQ02_RS12800	COG2257	FlhB HrpN YscU SpaS Family
LGQ02_RS12810	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGQ02_RS12825	COG0335	large ribosomal subunit rRNA binding
LGQ02_RS12830	COG0336	Belongs to the RNA methyltransferase TrmD family
LGQ02_RS12835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGQ02_RS12845	COG1837	Belongs to the UPF0109 family
LGQ02_RS12850	COG0228	four-way junction DNA binding
LGQ02_RS12855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGQ02_RS12860	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LGQ02_RS12865	COG0552	protein localization to endoplasmic reticulum
LGQ02_RS12870	COG1196	nuclear chromosome segregation
LGQ02_RS12875	COG4840	Belongs to the UPF0435 family
LGQ02_RS12910	COG0662	Cupin 2, conserved barrel domain protein
LGQ02_RS12955	COG0571	ribonuclease III activity
LGQ02_RS12960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGQ02_RS12965	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS12970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGQ02_RS12975	COG0416	fatty acid biosynthetic process
LGQ02_RS12980	COG1349	DNA-binding transcription factor activity
LGQ02_RS12985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGQ02_RS12990	COG1760	l-serine dehydratase
LGQ02_RS12995	COG1760	l-serine dehydratase
LGQ02_RS13000	COG1307	EDD domain protein, DegV family
LGQ02_RS13005	COG1461	Dihydroxyacetone kinase
LGQ02_RS13010	COG1302	Protein conserved in bacteria
LGQ02_RS13015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGQ02_RS13025	COG1564	THIamine pyrophosphokinase
LGQ02_RS13030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGQ02_RS13035	COG1162	GTPase activity
LGQ02_RS13040	COG2815	serine threonine protein kinase
LGQ02_RS13040	COG0515	serine threonine protein kinase
LGQ02_RS13045	COG0631	protein serine/threonine phosphatase activity
LGQ02_RS13050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGQ02_RS13050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGQ02_RS13055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGQ02_RS13060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGQ02_RS13065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGQ02_RS13070	COG1758	RNA polymerase activity
LGQ02_RS13075	COG0194	GDP metabolic process
LGQ02_RS13080	COG2052	Domain of unknown function (DUF370)
LGQ02_RS13085	COG1561	YicC-like family, N-terminal region
LGQ02_RS13095	COG1132	(ABC) transporter
LGQ02_RS13100	COG1132	(ABC) transporter
LGQ02_RS13115	COG0284	orotidine-5'-phosphate decarboxylase activity
LGQ02_RS13130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGQ02_RS13140	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LGQ02_RS13145	COG0540	Belongs to the ATCase OTCase family
LGQ02_RS13160	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LGQ02_RS13165	COG0564	pseudouridine synthase activity
LGQ02_RS13170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGQ02_RS13175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LGQ02_RS13180	COG3599	regulation of cell shape
LGQ02_RS13185	COG2302	S4 RNA-binding domain
LGQ02_RS13190	COG0762	integral membrane protein
LGQ02_RS13195	COG1799	cell septum assembly
LGQ02_RS13200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGQ02_RS13205	COG1873	PFAM PRC-barrel domain
LGQ02_RS13210	COG1191	sigma factor activity
LGQ02_RS13215	COG1191	sigma factor activity
LGQ02_RS13230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGQ02_RS13235	COG0849	cell division
LGQ02_RS13240	COG3856	small basic protein
LGQ02_RS13245	COG3879	Bacterial protein of unknown function (DUF881)
LGQ02_RS13250	COG3879	Bacterial protein of unknown function (DUF881)
LGQ02_RS13255	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGQ02_RS13260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGQ02_RS13265	COG0772	Belongs to the SEDS family
LGQ02_RS13270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LGQ02_RS13275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGQ02_RS13280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGQ02_RS13285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGQ02_RS13290	COG0768	penicillin binding
LGQ02_RS13295	COG0768	penicillin binding
LGQ02_RS13305	COG0275	rRNA processing
LGQ02_RS13310	COG2001	Belongs to the MraZ family
LGQ02_RS13315	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LGQ02_RS13325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGQ02_RS13330	COG0454	-acetyltransferase
LGQ02_RS13345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGQ02_RS13350	COG1399	metal-binding, possibly nucleic acid-binding protein
LGQ02_RS13355	COG1323	Belongs to the UPF0348 family
LGQ02_RS13365	COG3480	Lon protease (S16) C-terminal proteolytic domain
LGQ02_RS13370	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGQ02_RS13375	COG3314	Sporulation integral membrane protein YlbJ
LGQ02_RS13380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LGQ02_RS13385	COG0742	ribosomal rna small subunit methyltransferase
LGQ02_RS13390	COG4471	UPF0298 protein
LGQ02_RS13395	COG3679	Belongs to the UPF0342 family
LGQ02_RS13420	COG2340	Cysteine-rich secretory protein family
LGQ02_RS13425	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LGQ02_RS13435	COG0628	permease
LGQ02_RS13445	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGQ02_RS13450	COG1845	cytochrome c oxidase, subunit III
LGQ02_RS13455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGQ02_RS13460	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGQ02_RS13460	COG2010	Cytochrome c
LGQ02_RS13465	COG0109	protoheme IX farnesyltransferase activity
LGQ02_RS13470	COG1612	heme a metabolic process
LGQ02_RS13475	COG0783	Belongs to the Dps family
LGQ02_RS13480	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LGQ02_RS13485	COG4838	Belongs to the UPF0358 family
LGQ02_RS13490	COG2066	Belongs to the glutaminase family
LGQ02_RS13495	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGQ02_RS13500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LGQ02_RS13515	COG4896	Protein conserved in bacteria
LGQ02_RS13530	COG0483	inositol monophosphate 1-phosphatase activity
LGQ02_RS13540	COG4493	Belongs to the UPF0637 family
LGQ02_RS13545	COG4476	Belongs to the UPF0223 family
LGQ02_RS13550	COG1982	Orn Lys Arg decarboxylase major
LGQ02_RS13570	COG0726	polysaccharide deacetylase
LGQ02_RS13575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS13580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS13595	COG0022	dehydrogenase e1 component
LGQ02_RS13625	COG5503	Protein of unknown function (DUF1447)
LGQ02_RS13630	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGQ02_RS13635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS13640	COG0450	alkyl hydroperoxide reductase
LGQ02_RS13645	COG0668	transmembrane transport
LGQ02_RS13655	COG1473	amidohydrolase
LGQ02_RS13660	COG2171	N-acyltransferase activity
LGQ02_RS13675	COG0668	transmembrane transport
LGQ02_RS13680	COG1136	(ABC) transporter
LGQ02_RS13695	COG0778	Nitroreductase
LGQ02_RS13710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGQ02_RS13715	COG0626	cystathionine gamma-synthase activity
LGQ02_RS13730	COG2153	protein acetylation
LGQ02_RS13735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGQ02_RS13740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGQ02_RS13760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGQ02_RS13770	COG2323	membrane
LGQ02_RS13780	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGQ02_RS13815	COG1072	(Pantothenic acid kinase))
LGQ02_RS13825	COG3597	protein domain associated with
LGQ02_RS13830	COG2814	Major facilitator Superfamily
LGQ02_RS13845	COG0210	DNA helicase
LGQ02_RS13895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LGQ02_RS13900	COG0475	glutathione-regulated potassium exporter activity
LGQ02_RS13900	COG0569	domain protein
LGQ02_RS13905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LGQ02_RS13910	COG0564	pseudouridine synthase activity
LGQ02_RS13915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGQ02_RS13920	COG2357	RelA SpoT domain protein
LGQ02_RS13930	COG4116	CYTH
LGQ02_RS13940	COG2346	COG2346, Truncated hemoglobins
LGQ02_RS13950	COG1164	Oligoendopeptidase f
LGQ02_RS13960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGQ02_RS13965	COG4862	establishment of competence for transformation
LGQ02_RS13970	COG0861	Integral membrane protein TerC family
LGQ02_RS13975	COG1393	Belongs to the ArsC family
LGQ02_RS13980	COG0456	acetyltransferase
LGQ02_RS13990	COG1418	mRNA catabolic process
LGQ02_RS14005	COG0180	Tryptophanyl-tRNA synthetase
LGQ02_RS14020	COG5504	Zn-dependent protease
LGQ02_RS14025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGQ02_RS14030	COG2197	response regulator
LGQ02_RS14035	COG4585	Histidine kinase
LGQ02_RS14040	COG4758	membrane
LGQ02_RS14050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGQ02_RS14055	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGQ02_RS14070	COG1744	ABC transporter substrate-binding protein PnrA-like
LGQ02_RS14080	COG2267	carboxylic ester hydrolase activity
LGQ02_RS14100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGQ02_RS14105	COG1597	lipid kinase activity
LGQ02_RS14110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGQ02_RS14115	COG1597	lipid kinase activity
LGQ02_RS14120	COG0235	Class ii aldolase
LGQ02_RS14125	COG1063	alcohol dehydrogenase
LGQ02_RS14130	COG2223	nitrite transmembrane transporter activity
LGQ02_RS14135	COG2223	nitrite transmembrane transporter activity
LGQ02_RS14150	COG0437	4 iron, 4 sulfur cluster binding
LGQ02_RS14155	COG0243	molybdopterin cofactor binding
LGQ02_RS14165	COG4841	protein insertion into membrane
LGQ02_RS14180	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGQ02_RS14185	COG0314	molybdopterin synthase activity
LGQ02_RS14190	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGQ02_RS14195	COG0303	'Molybdopterin
LGQ02_RS14200	COG1999	signal sequence binding
LGQ02_RS14205	COG3336	cytochrome c oxidase
LGQ02_RS14210	COG0561	phosphatase activity
LGQ02_RS14230	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LGQ02_RS14255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGQ02_RS14265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS14280	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS14285	COG0628	permease
LGQ02_RS14300	COG3833	ABC-type maltose transport systems, permease component
LGQ02_RS14305	COG1175	transmembrane transport
LGQ02_RS14310	COG2182	Extracellular solute-binding protein
LGQ02_RS14315	COG0840	transmembrane signaling receptor activity
LGQ02_RS14320	COG1917	Cupin 2, conserved barrel domain protein
LGQ02_RS14320	COG2207	Transcriptional regulator
LGQ02_RS14325	COG0534	Mate efflux family protein
LGQ02_RS14330	COG2358	TRAP transporter, solute receptor (TAXI family
LGQ02_RS14340	COG1737	Transcriptional regulator
LGQ02_RS14345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGQ02_RS14350	COG1509	lysine 2,3-aminomutase activity
LGQ02_RS14365	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGQ02_RS14370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGQ02_RS14380	COG1032	radical SAM domain protein
LGQ02_RS14405	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGQ02_RS14420	COG0785	Cytochrome C biogenesis protein
LGQ02_RS14435	COG3300	MHYT domain
LGQ02_RS14435	COG5001	Diguanylate cyclase
LGQ02_RS14440	COG2154	pterin-4-alpha-carbinolamine dehydratase
LGQ02_RS14455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGQ02_RS14460	COG0640	Transcriptional regulator
LGQ02_RS14465	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LGQ02_RS14485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGQ02_RS14500	COG1272	protein, Hemolysin III
LGQ02_RS14520	COG2226	methyltransferase
LGQ02_RS14525	COG3290	protein histidine kinase activity
LGQ02_RS14525	COG0840	transmembrane signaling receptor activity
LGQ02_RS14540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGQ02_RS14550	COG2205	protein histidine kinase activity
LGQ02_RS14560	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LGQ02_RS14565	COG3300	MHYT domain
LGQ02_RS14565	COG5001	Diguanylate cyclase
LGQ02_RS14580	COG0686	Belongs to the AlaDH PNT family
LGQ02_RS14585	COG0840	transmembrane signaling receptor activity
LGQ02_RS14590	COG5001	Diguanylate cyclase
LGQ02_RS14610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LGQ02_RS14615	COG3639	organic phosphonate transmembrane transporter activity
LGQ02_RS14620	COG3639	organic phosphonate transmembrane transporter activity
LGQ02_RS14640	COG1234	tRNA 3'-trailer cleavage
LGQ02_RS14645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LGQ02_RS14650	COG2868	ribosomal protein
LGQ02_RS14655	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LGQ02_RS14660	COG1530	ribonuclease E activity
LGQ02_RS14665	COG1994	Peptidase M50
LGQ02_RS14670	COG0739	heme binding
LGQ02_RS14680	COG2894	cell division
LGQ02_RS14685	COG0850	regulation of cytokinetic process
LGQ02_RS14690	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGQ02_RS14700	COG1077	Cell shape determining protein MreB Mrl
LGQ02_RS14705	COG2003	Belongs to the UPF0758 family
LGQ02_RS14710	COG0424	maF-like protein
LGQ02_RS14715	COG1027	Aspartate ammonia-lyase
LGQ02_RS14740	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGQ02_RS14750	COG1459	type II secretion system
LGQ02_RS14760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGQ02_RS14775	COG2199	diguanylate cyclase activity
LGQ02_RS14775	COG2203	Gaf domain
LGQ02_RS14780	COG0285	dihydrofolate synthase activity
LGQ02_RS14785	COG0189	ligase activity
LGQ02_RS14805	COG1082	Xylose isomerase domain protein TIM barrel
LGQ02_RS14825	COG0697	spore germination
LGQ02_RS14830	COG2197	response regulator
LGQ02_RS14865	COG0525	valine-tRNA ligase activity
LGQ02_RS14875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGQ02_RS14885	COG1388	LysM domain
LGQ02_RS14885	COG1388	LysM domain
LGQ02_RS14895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGQ02_RS14900	COG0113	porphobilinogen synthase activity
LGQ02_RS14910	COG0181	hydroxymethylbilane synthase activity
LGQ02_RS14915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGQ02_RS14920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGQ02_RS14930	COG4974	Belongs to the 'phage' integrase family
LGQ02_RS14935	COG1126	abc transporter atp-binding protein
LGQ02_RS14940	COG0765	amino acid transport
LGQ02_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGQ02_RS14950	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGQ02_RS14955	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGQ02_RS14960	COG0470	DNA polymerase III
LGQ02_RS14960	COG1067	ATP-dependent peptidase activity
LGQ02_RS14965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGQ02_RS14970	COG0544	peptidyl-prolyl cis-trans isomerase activity
LGQ02_RS14975	COG0457	Tetratricopeptide repeat
LGQ02_RS14975	COG1477	protein flavinylation
LGQ02_RS15010	COG3344	reverse transcriptase
LGQ02_RS15025	COG3300	MHYT domain
LGQ02_RS15025	COG5001	Diguanylate cyclase
LGQ02_RS15050	COG0622	Phosphoesterase
LGQ02_RS15055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGQ02_RS15065	COG5401	PFAM Sporulation and spore germination
LGQ02_RS15090	COG1484	DNA-dependent DNA replication
LGQ02_RS15105	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS15120	COG0840	transmembrane signaling receptor activity
LGQ02_RS15150	COG1846	Transcriptional regulator
LGQ02_RS15165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGQ02_RS15170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGQ02_RS15175	COG3711	transcriptional antiterminator
LGQ02_RS15180	COG2197	response regulator
LGQ02_RS15185	COG0824	Thioesterase
LGQ02_RS15190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGQ02_RS15195	COG1053	succinate dehydrogenase
LGQ02_RS15200	COG2009	succinate dehydrogenase
LGQ02_RS15205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGQ02_RS15210	COG1719	4-vinyl reductase, 4VR
LGQ02_RS15245	COG0322	excinuclease ABC activity
LGQ02_RS15250	COG3118	belongs to the thioredoxin family
LGQ02_RS15255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LGQ02_RS15260	COG2086	electron transfer activity
LGQ02_RS15265	COG1024	Enoyl-CoA hydratase
LGQ02_RS15270	COG1309	transcriptional regulator
LGQ02_RS15275	COG0318	PFAM AMP-dependent synthetase and ligase
LGQ02_RS15280	COG0318	PFAM AMP-dependent synthetase and ligase
LGQ02_RS15290	COG3766	membrane
LGQ02_RS15295	COG1193	negative regulation of DNA recombination
LGQ02_RS15300	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LGQ02_RS15300	COG1796	DNA polymerase
LGQ02_RS15305	COG3344	reverse transcriptase
LGQ02_RS15315	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGQ02_RS15320	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGQ02_RS15345	COG0072	phenylalanine-tRNA ligase activity
LGQ02_RS15345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGQ02_RS15350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LGQ02_RS15355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGQ02_RS15365	COG1363	Peptidase, m42
LGQ02_RS15395	COG4721	ABC-type cobalt transport system, permease component
LGQ02_RS15400	COG4172	Belongs to the ABC transporter superfamily
LGQ02_RS15405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LGQ02_RS15410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LGQ02_RS15420	COG1793	dna ligase
LGQ02_RS15425	COG1793	dna ligase
LGQ02_RS15425	COG3285	dna ligase
LGQ02_RS15430	COG0398	Pfam SNARE associated Golgi protein
LGQ02_RS15440	COG1126	abc transporter atp-binding protein
LGQ02_RS15445	COG0765	amino acid transport
LGQ02_RS15450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGQ02_RS15455	COG1126	abc transporter atp-binding protein
LGQ02_RS15460	COG0765	amino acid transport
LGQ02_RS15470	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LGQ02_RS15475	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LGQ02_RS15480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LGQ02_RS15500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LGQ02_RS15510	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LGQ02_RS15515	COG1484	DNA-dependent DNA replication
LGQ02_RS15520	COG3611	Membrane attachment protein
LGQ02_RS15525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGQ02_RS15535	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LGQ02_RS15540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGQ02_RS15545	COG0237	dephospho-CoA kinase activity
LGQ02_RS15550	COG1971	Probably functions as a manganese efflux pump
LGQ02_RS15555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LGQ02_RS15560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGQ02_RS15560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGQ02_RS15565	COG5002	protein histidine kinase activity
LGQ02_RS15570	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS15580	COG0039	L-malate dehydrogenase activity
LGQ02_RS15585	COG0538	isocitrate dehydrogenase activity
LGQ02_RS15590	COG0372	Belongs to the citrate synthase family
LGQ02_RS15595	COG2707	UPF0756 membrane protein
LGQ02_RS15600	COG0628	permease
LGQ02_RS15605	COG3030	protein affecting phage T7 exclusion by the F plasmid
LGQ02_RS15615	COG0205	6-phosphofructokinase activity
LGQ02_RS15620	COG0825	malonyl-CoA metabolic process
LGQ02_RS15625	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LGQ02_RS15630	COG2186	Transcriptional regulator
LGQ02_RS15635	COG0281	malic enzyme
LGQ02_RS15640	COG0587	DNA-directed DNA polymerase activity
LGQ02_RS15660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LGQ02_RS15670	COG4109	DRTGG domain
LGQ02_RS15680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LGQ02_RS15685	COG0006	proline dipeptidase activity
LGQ02_RS15695	COG1028	Short-chain dehydrogenase reductase Sdr
LGQ02_RS15720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGQ02_RS15725	COG0827	DNA restriction-modification system
LGQ02_RS15745	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGQ02_RS15750	COG3874	Sporulation protein YtfJ
LGQ02_RS15760	COG1714	RDD family
LGQ02_RS15765	COG0616	signal peptide processing
LGQ02_RS15770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGQ02_RS15775	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LGQ02_RS15785	COG0301	tRNA thio-modification
LGQ02_RS15790	COG1104	cysteine desulfurase activity
LGQ02_RS15795	COG1114	Component of the transport system for branched-chain amino acids
LGQ02_RS15810	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LGQ02_RS15815	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LGQ02_RS15820	COG1309	transcriptional regulator
LGQ02_RS15825	COG1956	GAF domain-containing protein
LGQ02_RS15830	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGQ02_RS15845	COG0454	-acetyltransferase
LGQ02_RS15850	COG0517	IMP dehydrogenase activity
LGQ02_RS15855	COG0123	including yeast histone deacetylase and acetoin utilization protein
LGQ02_RS15860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGQ02_RS15885	COG1605	Chorismate mutase
LGQ02_RS15885	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LGQ02_RS15890	COG0849	cell division
LGQ02_RS15895	COG3118	belongs to the thioredoxin family
LGQ02_RS15900	COG4980	gas vesicle protein
LGQ02_RS15915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGQ02_RS15935	COG1674	ftsk spoiiie
LGQ02_RS15940	COG4848	Belongs to the UPF0354 family
LGQ02_RS15945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGQ02_RS15965	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGQ02_RS15970	COG1363	Peptidase, m42
LGQ02_RS15980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGQ02_RS15985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LGQ02_RS16000	COG0510	thiamine kinase activity
LGQ02_RS16015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGQ02_RS16025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGQ02_RS16030	COG1349	DNA-binding transcription factor activity
LGQ02_RS16035	COG1187	pseudouridine synthase activity
LGQ02_RS16045	COG0772	Belongs to the SEDS family
LGQ02_RS16050	COG0772	Belongs to the SEDS family
LGQ02_RS16055	COG1733	regulation of RNA biosynthetic process
LGQ02_RS16060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGQ02_RS16070	COG0352	thiamine-phosphate diphosphorylase activity
LGQ02_RS16075	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LGQ02_RS16080	COG2022	thiamine diphosphate biosynthetic process
LGQ02_RS16085	COG0351	phosphomethylpyrimidine kinase
LGQ02_RS16090	COG0352	thiamine-phosphate diphosphorylase activity
LGQ02_RS16095	COG2244	polysaccharide biosynthetic process
LGQ02_RS16105	COG0432	Pfam Uncharacterised protein family UPF0047
LGQ02_RS16110	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGQ02_RS16115	COG2022	thiamine diphosphate biosynthetic process
LGQ02_RS16120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGQ02_RS16130	COG1595	DNA-templated transcription, initiation
LGQ02_RS16140	COG2081	HI0933 family
LGQ02_RS16160	COG1785	Belongs to the alkaline phosphatase family
LGQ02_RS16170	COG0495	leucyl-tRNA aminoacylation
LGQ02_RS16175	COG2814	Major facilitator Superfamily
LGQ02_RS16180	COG0531	amino acid
LGQ02_RS16195	COG1242	4 iron, 4 sulfur cluster binding
LGQ02_RS16200	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LGQ02_RS16220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGQ02_RS16230	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGQ02_RS16235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGQ02_RS16240	COG1116	anion transmembrane transporter activity
LGQ02_RS16245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGQ02_RS16250	COG0494	nUDIX hydrolase
LGQ02_RS16255	COG0460	homoserine dehydrogenase
LGQ02_RS16260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGQ02_RS16270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGQ02_RS16285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGQ02_RS16290	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGQ02_RS16295	COG1910	domain protein
LGQ02_RS16300	COG0303	'Molybdopterin
LGQ02_RS16305	COG0746	molybdenum cofactor guanylyltransferase activity
LGQ02_RS16320	COG0437	4 iron, 4 sulfur cluster binding
LGQ02_RS16330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LGQ02_RS16350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGQ02_RS16355	COG0640	Transcriptional regulator
LGQ02_RS16365	COG0588	phosphoglycerate mutase activity
LGQ02_RS16385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS16390	COG1937	Protein conserved in bacteria
LGQ02_RS16410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGQ02_RS16415	COG0584	glycerophosphoryl diester phosphodiesterase
LGQ02_RS16420	COG2133	pyrroloquinoline quinone binding
LGQ02_RS16430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGQ02_RS16435	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGQ02_RS16460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGQ02_RS16465	COG1882	Formate acetyltransferase
LGQ02_RS16470	COG1191	sigma factor activity
LGQ02_RS16495	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LGQ02_RS16500	COG1363	Peptidase, m42
LGQ02_RS16505	COG1404	Belongs to the peptidase S8 family
LGQ02_RS16510	COG3344	reverse transcriptase
LGQ02_RS16520	COG2197	response regulator
LGQ02_RS16525	COG4585	Histidine kinase
LGQ02_RS16530	COG0714	Associated with various cellular activities
LGQ02_RS16545	COG1523	belongs to the glycosyl hydrolase 13 family
LGQ02_RS16550	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGQ02_RS16555	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGQ02_RS16560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGQ02_RS16565	COG0297	glycogen (starch) synthase activity
LGQ02_RS16570	COG0058	SHG alpha-glucan phosphorylase activity
LGQ02_RS16575	COG0596	Alpha beta hydrolase
LGQ02_RS16585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS16595	COG1335	isochorismatase
LGQ02_RS16600	COG1510	regulation of RNA biosynthetic process
LGQ02_RS16625	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LGQ02_RS16630	COG3639	organic phosphonate transmembrane transporter activity
LGQ02_RS16650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGQ02_RS16660	COG2391	methyltransferase activity
LGQ02_RS16665	COG2226	methyltransferase
LGQ02_RS16670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGQ02_RS16685	COG5002	protein histidine kinase activity
LGQ02_RS16715	COG2204	response regulator
LGQ02_RS16720	COG4191	Histidine kinase
LGQ02_RS16735	COG0437	4 iron, 4 sulfur cluster binding
LGQ02_RS16750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGQ02_RS16760	COG2502	aspartate--ammonia ligase
LGQ02_RS16780	COG2223	nitrite transmembrane transporter activity
LGQ02_RS16785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGQ02_RS16800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGQ02_RS16805	COG1940	carbohydrate kinase activity
LGQ02_RS16820	COG3119	arylsulfatase activity
LGQ02_RS16845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LGQ02_RS16865	COG1263	PTS System
LGQ02_RS16865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGQ02_RS16865	COG2190	(PTS) system
LGQ02_RS16870	COG3711	transcriptional antiterminator
LGQ02_RS16885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGQ02_RS16895	COG1131	(ABC) transporter
LGQ02_RS16915	COG1138	Cytochrome C-type biogenesis protein
LGQ02_RS16930	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LGQ02_RS16935	COG3005	denitrification pathway
LGQ02_RS16950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGQ02_RS16960	COG0166	Belongs to the GPI family
LGQ02_RS16965	COG1979	alcohol dehydrogenase
LGQ02_RS16970	COG2155	Conserved Protein
LGQ02_RS16975	COG1098	S1 RNA binding domain
LGQ02_RS16980	COG0733	neurotransmitter:sodium symporter activity
LGQ02_RS16985	COG0436	Aminotransferase
LGQ02_RS16990	COG1522	sequence-specific DNA binding
LGQ02_RS16995	COG1335	isochorismatase
LGQ02_RS17005	COG0644	oxidoreductase
LGQ02_RS17010	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LGQ02_RS17020	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
LGQ02_RS17025	COG1131	(ABC) transporter
LGQ02_RS17030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGQ02_RS17035	COG0791	NLP P60 protein
LGQ02_RS17155	COG2056	Na+-H+ antiporter family
LGQ02_RS17160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LGQ02_RS17165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LGQ02_RS17175	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LGQ02_RS17180	COG3584	3D domain protein
LGQ02_RS17195	COG1252	NADH dehydrogenase
LGQ02_RS17200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGQ02_RS17205	COG0316	Belongs to the HesB IscA family
LGQ02_RS17210	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LGQ02_RS17215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGQ02_RS17225	COG4844	belongs to the
LGQ02_RS17230	COG1252	NADH dehydrogenase
LGQ02_RS17235	COG4837	Protein of unknown function (DUF1462)
LGQ02_RS17240	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LGQ02_RS17245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGQ02_RS17250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGQ02_RS17255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGQ02_RS17260	COG0647	UMP catabolic process
LGQ02_RS17270	COG2445	Protein of unknown function DUF86
LGQ02_RS17275	COG1494	fructose-1,6-bisphosphatase
LGQ02_RS17290	COG4470	Protein conserved in bacteria
LGQ02_RS17300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGQ02_RS17305	COG0739	heme binding
LGQ02_RS17310	COG0733	neurotransmitter:sodium symporter activity
LGQ02_RS17315	COG1757	Na H antiporter
LGQ02_RS17320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LGQ02_RS17325	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LGQ02_RS17335	COG3377	Domain of unknown function (DUF1805)
LGQ02_RS17340	COG0737	Belongs to the 5'-nucleotidase family
LGQ02_RS17345	COG0730	response to heat
LGQ02_RS17350	COG1801	Protein of unknown function DUF72
LGQ02_RS17360	COG0719	Fe-S assembly protein
LGQ02_RS17365	COG0822	iron-sulfur transferase activity
LGQ02_RS17370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGQ02_RS17375	COG0719	Fe-S assembly protein
LGQ02_RS17380	COG0396	ATPase activity
LGQ02_RS17390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LGQ02_RS17395	COG1464	Belongs to the NlpA lipoprotein family
LGQ02_RS17400	COG2011	ABC-type metal ion transport system permease component
LGQ02_RS17405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGQ02_RS17425	COG0509	glycine decarboxylation via glycine cleavage system
LGQ02_RS17430	COG1393	Belongs to the ArsC family
LGQ02_RS17440	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS17445	COG0183	Belongs to the thiolase family
LGQ02_RS17450	COG1024	Enoyl-CoA hydratase
LGQ02_RS17450	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGQ02_RS17460	COG5577	PFAM Coat F domain
LGQ02_RS17470	COG0201	protein transport
LGQ02_RS17480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LGQ02_RS17485	COG2226	methyltransferase
LGQ02_RS17495	COG5002	protein histidine kinase activity
LGQ02_RS17500	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS17515	COG1271	oxidase subunit
LGQ02_RS17520	COG1294	oxidase, subunit
LGQ02_RS17530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGQ02_RS17535	COG4988	ABC transporter
LGQ02_RS17545	COG2323	membrane
LGQ02_RS17570	COG1063	alcohol dehydrogenase
LGQ02_RS17580	COG1607	acyl-coa hydrolase
LGQ02_RS17590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS17600	COG2814	Major facilitator Superfamily
LGQ02_RS17620	COG0189	ligase activity
LGQ02_RS17650	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGQ02_RS17670	COG0557	exoribonuclease II activity
LGQ02_RS17675	COG1647	Serine aminopeptidase, S33
LGQ02_RS17680	COG0596	Alpha beta hydrolase
LGQ02_RS17685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGQ02_RS17695	COG0148	phosphopyruvate hydratase activity
LGQ02_RS17700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGQ02_RS17705	COG0149	triose-phosphate isomerase activity
LGQ02_RS17710	COG0126	phosphoglycerate kinase activity
LGQ02_RS17715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGQ02_RS17730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGQ02_RS17740	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGQ02_RS17745	COG1481	regulation of sporulation
LGQ02_RS17750	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGQ02_RS17755	COG1660	Displays ATPase and GTPase activities
LGQ02_RS17760	COG1051	belongs to the nudix hydrolase family
LGQ02_RS17765	COG0492	ferredoxin-NADP+ reductase activity
LGQ02_RS17770	COG0457	Tetratricopeptide repeat
LGQ02_RS17785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGQ02_RS17785	COG0140	phosphoribosyl-ATP diphosphatase activity
LGQ02_RS17790	COG0107	imidazoleglycerol-phosphate synthase activity
LGQ02_RS17795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGQ02_RS17800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGQ02_RS17805	COG0131	Imidazoleglycerol-phosphate dehydratase
LGQ02_RS17810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGQ02_RS17815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LGQ02_RS17820	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LGQ02_RS17825	COG0110	maltose O-acetyltransferase activity
LGQ02_RS17830	COG0546	phosphoglycolate phosphatase activity
LGQ02_RS17835	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LGQ02_RS17840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGQ02_RS17845	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LGQ02_RS17850	COG1950	PFAM Membrane protein of
LGQ02_RS17855	COG1983	PspC domain protein
LGQ02_RS17860	COG3595	metallopeptidase activity
LGQ02_RS17865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGQ02_RS17870	COG0556	nucleotide-excision repair
LGQ02_RS17875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGQ02_RS17880	COG3409	Peptidoglycan-binding domain 1 protein
LGQ02_RS17880	COG0793	Belongs to the peptidase S41A family
LGQ02_RS17890	COG2177	Part of the ABC transporter FtsEX involved in
LGQ02_RS17895	COG2884	Cell division ATP-binding protein ftsE
LGQ02_RS17900	COG2010	Cytochrome c
LGQ02_RS17905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGQ02_RS17915	COG0653	protein targeting
LGQ02_RS17920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGQ02_RS17925	COG1278	Cold shock
LGQ02_RS17930	COG0367	asparagine synthase
LGQ02_RS17940	COG0629	single-stranded DNA binding
LGQ02_RS17950	COG1482	cell wall glycoprotein biosynthetic process
LGQ02_RS17965	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGQ02_RS17985	COG1516	flagellar protein fliS
LGQ02_RS17990	COG1334	flagellar protein FlaG
LGQ02_RS18000	COG0006	proline dipeptidase activity
LGQ02_RS18005	COG3344	reverse transcriptase
LGQ02_RS18010	COG5002	protein histidine kinase activity
LGQ02_RS18015	COG5002	protein histidine kinase activity
LGQ02_RS18025	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LGQ02_RS18030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LGQ02_RS18065	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGQ02_RS18070	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LGQ02_RS18080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LGQ02_RS18085	COG4786	Flagellar basal body rod
LGQ02_RS18085	COG1256	bacterial-type flagellum assembly
LGQ02_RS18095	COG2747	anti-sigma28 factor FlgM
LGQ02_RS18105	COG1040	competence protein
LGQ02_RS18110	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LGQ02_RS18115	COG1307	EDD domain protein, DegV family
LGQ02_RS18270	COG1739	Uncharacterized protein family UPF0029
LGQ02_RS18280	COG1316	TRANSCRIPTIONal
LGQ02_RS18290	COG1404	Belongs to the peptidase S8 family
LGQ02_RS18295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGQ02_RS18300	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LGQ02_RS18310	COG1682	transport, permease protein
LGQ02_RS18315	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGQ02_RS18320	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGQ02_RS18325	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGQ02_RS18330	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGQ02_RS18330	COG1215	transferase activity, transferring glycosyl groups
LGQ02_RS18335	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGQ02_RS18340	COG0463	Glycosyl transferase, family 2
LGQ02_RS18340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGQ02_RS18350	COG1215	transferase activity, transferring glycosyl groups
LGQ02_RS18350	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGQ02_RS18360	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGQ02_RS18360	COG2247	cell wall binding repeat
LGQ02_RS18405	COG3012	SEC-C Motif Domain Protein
LGQ02_RS18405	COG1405	negative regulation of cell septum assembly
LGQ02_RS18410	COG2843	Capsule synthesis protein
LGQ02_RS18420	COG1388	LysM domain
LGQ02_RS18420	COG3584	3D domain protein
LGQ02_RS18450	COG1473	amidohydrolase
LGQ02_RS18455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LGQ02_RS18465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGQ02_RS18470	COG0196	riboflavin kinase activity
LGQ02_RS18475	COG2267	carboxylic ester hydrolase activity
LGQ02_RS18485	COG0183	Belongs to the thiolase family
LGQ02_RS18495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGQ02_RS18500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGQ02_RS18505	COG3485	protocatechuate 3,4-dioxygenase
LGQ02_RS18515	COG3835	regulator
LGQ02_RS18530	COG3852	Histidine kinase
LGQ02_RS18545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LGQ02_RS18560	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LGQ02_RS18565	COG0698	ribose 5-phosphate isomerase
LGQ02_RS18570	COG0149	triose-phosphate isomerase activity
LGQ02_RS18580	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS18585	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
LGQ02_RS18595	COG4869	propanediol catabolic process
LGQ02_RS18600	COG2390	Transcriptional regulator
LGQ02_RS18610	COG2056	Na+-H+ antiporter family
LGQ02_RS18615	COG2986	histidine ammonia-lyase
LGQ02_RS18625	COG1363	Peptidase, m42
LGQ02_RS18630	COG2235	arginine
LGQ02_RS18635	COG0726	polysaccharide deacetylase
LGQ02_RS18665	COG1473	amidohydrolase
LGQ02_RS18720	COG3718	enzyme involved in inositol metabolism
LGQ02_RS18735	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS18755	COG0667	Aldo Keto reductase
LGQ02_RS18765	COG1940	carbohydrate kinase activity
LGQ02_RS18775	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS18780	COG1175	transmembrane transport
LGQ02_RS18790	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LGQ02_RS18795	COG2207	Transcriptional regulator
LGQ02_RS18800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGQ02_RS18805	COG1486	melibiose metabolic process
LGQ02_RS18810	COG0673	inositol 2-dehydrogenase activity
LGQ02_RS18820	COG1609	Transcriptional regulator
LGQ02_RS18825	COG1082	Xylose isomerase domain protein TIM barrel
LGQ02_RS18835	COG1012	belongs to the aldehyde dehydrogenase family
LGQ02_RS18845	COG3718	enzyme involved in inositol metabolism
LGQ02_RS18850	COG0673	inositol 2-dehydrogenase activity
LGQ02_RS18855	COG1082	Xylose isomerase domain protein TIM barrel
LGQ02_RS18860	COG0561	phosphatase activity
LGQ02_RS18870	COG3842	ATPase activity
LGQ02_RS18880	COG1840	ABC-type Fe3 transport system, periplasmic component
LGQ02_RS18885	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS18890	COG1175	transmembrane transport
LGQ02_RS18895	COG1653	transport
LGQ02_RS18900	COG1609	Transcriptional regulator
LGQ02_RS18905	COG3459	Glycosyltransferase 36 associated
LGQ02_RS18940	COG1929	Belongs to the glycerate kinase type-1 family
LGQ02_RS18950	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS18965	COG1609	Transcriptional regulator
LGQ02_RS18970	COG0438	transferase activity, transferring glycosyl groups
LGQ02_RS18985	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGQ02_RS18990	COG0726	polysaccharide deacetylase
LGQ02_RS18990	COG1649	PFAM Uncharacterised BCR, COG1649
LGQ02_RS18995	COG0747	negative chemotaxis
LGQ02_RS19000	COG0747	negative chemotaxis
LGQ02_RS19005	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS19010	COG1175	transmembrane transport
LGQ02_RS19020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGQ02_RS19030	COG1609	Transcriptional regulator
LGQ02_RS19035	COG3344	reverse transcriptase
LGQ02_RS19055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGQ02_RS19060	COG1346	cytolysis
LGQ02_RS19070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGQ02_RS19075	COG3266	domain, Protein
LGQ02_RS19075	COG2911	Protein conserved in bacteria
LGQ02_RS19075	COG1361	Conserved repeat domain
LGQ02_RS19080	COG2252	PERMEase
LGQ02_RS19085	COG1523	belongs to the glycosyl hydrolase 13 family
LGQ02_RS19100	COG0840	transmembrane signaling receptor activity
LGQ02_RS19120	COG2201	protein-glutamate methylesterase activity
LGQ02_RS19135	COG0561	phosphatase activity
LGQ02_RS19140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGQ02_RS19165	COG5564	TIM-barrel signal transduction protein
LGQ02_RS19190	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS19195	COG1175	transmembrane transport
LGQ02_RS19205	COG2972	Histidine kinase
LGQ02_RS19210	COG4753	response regulator
LGQ02_RS19210	COG2207	Transcriptional regulator
LGQ02_RS19215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGQ02_RS19220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGQ02_RS19245	COG0800	Aldolase
LGQ02_RS19260	COG1414	Transcriptional regulator
LGQ02_RS19275	COG0747	negative chemotaxis
LGQ02_RS19280	COG0006	proline dipeptidase activity
LGQ02_RS19290	COG0501	Belongs to the peptidase M48B family
LGQ02_RS19325	COG0006	proline dipeptidase activity
LGQ02_RS19335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LGQ02_RS19335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LGQ02_RS19340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LGQ02_RS19360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LGQ02_RS19370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LGQ02_RS19375	COG1802	Transcriptional regulator
LGQ02_RS19415	COG3949	Membrane
LGQ02_RS19420	COG4948	Mandelate Racemase Muconate Lactonizing
LGQ02_RS19430	COG1473	amidohydrolase
LGQ02_RS19465	COG1484	DNA-dependent DNA replication
LGQ02_RS19500	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGQ02_RS19515	COG2089	acid synthase
LGQ02_RS19520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGQ02_RS19525	COG3980	spore coat polysaccharide biosynthesis protein
LGQ02_RS19530	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
LGQ02_RS19535	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGQ02_RS19540	COG1086	Polysaccharide biosynthesis protein
LGQ02_RS19585	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LGQ02_RS19590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGQ02_RS19600	COG4464	protein tyrosine phosphatase activity
LGQ02_RS19605	COG0489	protein tyrosine kinase activity
LGQ02_RS19610	COG3944	biosynthesis protein
LGQ02_RS19615	COG1316	TRANSCRIPTIONal
LGQ02_RS19635	COG1388	LysM domain
LGQ02_RS19635	COG0791	NLP P60 protein
LGQ02_RS19640	COG0768	penicillin binding
LGQ02_RS19645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGQ02_RS19650	COG3011	Protein conserved in bacteria
LGQ02_RS19660	COG2259	Doxx family
LGQ02_RS19665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGQ02_RS19675	COG0791	NLP P60 protein
LGQ02_RS19675	COG1388	LysM domain
LGQ02_RS19690	COG2364	Membrane
LGQ02_RS19695	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGQ02_RS19700	COG1737	Transcriptional regulator
LGQ02_RS19705	COG1472	Belongs to the glycosyl hydrolase 3 family
LGQ02_RS19710	COG0395	ABC-type sugar transport system, permease component
LGQ02_RS19715	COG1175	transmembrane transport
LGQ02_RS19725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LGQ02_RS19730	COG2385	sporulation resulting in formation of a cellular spore
LGQ02_RS19740	COG3876	Protein conserved in bacteria
LGQ02_RS19745	COG2971	BadF BadG BcrA BcrD
LGQ02_RS19750	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGQ02_RS19770	COG2843	Capsule synthesis protein
LGQ02_RS19780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LGQ02_RS19820	COG4786	Flagellar basal body rod
LGQ02_RS19825	COG4786	Flagellar basal body rod
LGQ02_RS19830	COG1077	Cell shape determining protein MreB Mrl
LGQ02_RS19835	COG1609	Transcriptional regulator
LGQ02_RS19840	COG0739	heme binding
LGQ02_RS19845	COG2385	sporulation resulting in formation of a cellular spore
LGQ02_RS19850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGQ02_RS19865	COG1007	ATP synthesis coupled electron transport
LGQ02_RS19875	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGQ02_RS19885	COG0839	Belongs to the complex I subunit 6 family
LGQ02_RS19890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGQ02_RS19895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGQ02_RS19900	COG0649	NAD binding
LGQ02_RS19905	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGQ02_RS19910	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGQ02_RS19920	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGQ02_RS19925	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LGQ02_RS19930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGQ02_RS19935	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGQ02_RS19940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LGQ02_RS19945	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGQ02_RS19955	COG0356	it plays a direct role in the translocation of protons across the membrane
LGQ02_RS19975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGQ02_RS19980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGQ02_RS19985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LGQ02_RS19990	COG4475	Protein of unknown function (DUF436)
LGQ02_RS19995	COG0698	ribose 5-phosphate isomerase
LGQ02_RS20000	COG0840	transmembrane signaling receptor activity
LGQ02_RS20015	COG0009	L-threonylcarbamoyladenylate synthase
LGQ02_RS20035	COG2890	protein-(glutamine-N5) methyltransferase activity
LGQ02_RS20040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGQ02_RS20045	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGQ02_RS20055	COG1435	thymidine kinase activity
LGQ02_RS20060	COG0254	rRNA binding
LGQ02_RS20065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGQ02_RS20070	COG1494	fructose-1,6-bisphosphatase
LGQ02_RS20075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGQ02_RS20080	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGQ02_RS20085	COG0191	fructose-bisphosphate aldolase activity
LGQ02_RS20090	COG2204	response regulator
LGQ02_RS20100	COG1115	amino acid carrier protein
LGQ02_RS20105	COG0504	CTP synthase activity
LGQ02_RS20110	COG3343	RNA polymerase activity
LGQ02_RS20115	COG1703	isobutyryl-CoA mutase activity
LGQ02_RS20115	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LGQ02_RS20115	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LGQ02_RS20120	COG1309	transcriptional regulator
LGQ02_RS20125	COG1703	isobutyryl-CoA mutase activity
LGQ02_RS20130	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS20135	COG1960	acyl-CoA dehydrogenase activity
LGQ02_RS20140	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGQ02_RS20145	COG0183	Belongs to the thiolase family
LGQ02_RS20150	COG0247	lactate metabolic process
LGQ02_RS20150	COG2181	nitrate reductase activity
LGQ02_RS20155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGQ02_RS20160	COG2217	Heavy metal translocating P-type atpase
LGQ02_RS20165	COG2267	carboxylic ester hydrolase activity
LGQ02_RS20175	COG0018	arginyl-trna synthetase
LGQ02_RS20185	COG0010	Belongs to the arginase family
LGQ02_RS20190	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGQ02_RS20195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGQ02_RS20215	COG3465	dGTPase activity
LGQ02_RS20220	COG1078	dGTPase activity
LGQ02_RS20225	COG4844	belongs to the
LGQ02_RS20235	COG2746	aminoglycoside 3-N-acetyltransferase activity
LGQ02_RS20240	COG0488	(ABC) transporter
LGQ02_RS20245	COG0280	phosphate acetyltransferase
LGQ02_RS20250	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGQ02_RS20250	COG1902	pentaerythritol trinitrate reductase activity
LGQ02_RS20255	COG1024	Enoyl-CoA hydratase
LGQ02_RS20260	COG3253	May function as heme-dependent peroxidase
LGQ02_RS20265	COG3773	Cell wall hydrolase
LGQ02_RS20280	COG3773	Cell wall hydrolase
LGQ02_RS20285	COG2363	Small membrane protein
LGQ02_RS20300	COG0456	acetyltransferase
LGQ02_RS20320	COG3852	Histidine kinase
LGQ02_RS20325	COG2084	Dehydrogenase
LGQ02_RS20330	COG0656	L-ascorbic acid biosynthetic process
LGQ02_RS20335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LGQ02_RS20345	COG1621	beta-fructofuranosidase activity
LGQ02_RS20360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LGQ02_RS20375	COG1368	sulfuric ester hydrolase activity
LGQ02_RS20380	COG2309	aminopeptidase activity
LGQ02_RS20385	COG3314	Sporulation integral membrane protein YlbJ
LGQ02_RS20390	COG0251	oxidation-reduction process
LGQ02_RS20395	COG1984	allophanate hydrolase subunit 2
LGQ02_RS20400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGQ02_RS20405	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGQ02_RS20415	COG0444	Belongs to the ABC transporter superfamily
LGQ02_RS20420	COG4608	Belongs to the ABC transporter superfamily
LGQ02_RS20425	COG0747	negative chemotaxis
LGQ02_RS20430	COG0601	transmembrane transport
LGQ02_RS20435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGQ02_RS20440	COG0183	Belongs to the thiolase family
LGQ02_RS20445	COG0737	Belongs to the 5'-nucleotidase family
LGQ02_RS20445	COG1525	nuclease
LGQ02_RS20445	COG4085	toxin activity
LGQ02_RS20455	COG0701	Predicted permease
LGQ02_RS20460	COG1970	mechanosensitive ion channel activity
LGQ02_RS20465	COG0723	plastoquinol--plastocyanin reductase activity
LGQ02_RS20465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGQ02_RS20485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGQ02_RS20495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LGQ02_RS20510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LGQ02_RS20515	COG0243	molybdopterin cofactor binding
LGQ02_RS20545	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LGQ02_RS20570	COG3448	diguanylate cyclase activity
LGQ02_RS20570	COG4175	Glycine betaine
LGQ02_RS20590	COG2894	cell division
LGQ02_RS20640	COG2323	membrane
LGQ02_RS20645	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGQ02_RS20650	COG2224	Isocitrate lyase
LGQ02_RS20660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGQ02_RS20665	COG1959	2 iron, 2 sulfur cluster binding
LGQ02_RS20675	COG1126	abc transporter atp-binding protein
LGQ02_RS20680	COG0765	amino acid transport
LGQ02_RS20685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGQ02_RS20715	COG1510	regulation of RNA biosynthetic process
LGQ02_RS20730	COG0165	Argininosuccinate lyase
LGQ02_RS20735	COG0137	argininosuccinate synthase activity
LGQ02_RS20740	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LGQ02_RS20750	COG0505	Belongs to the CarA family
LGQ02_RS20755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGQ02_RS20790	COG1234	tRNA 3'-trailer cleavage
LGQ02_RS20795	COG1612	heme a metabolic process
LGQ02_RS20810	COG3383	formate dehydrogenase (NAD+) activity
LGQ02_RS20815	COG5609	conserved protein (DUF2294)
LGQ02_RS20820	COG2223	nitrite transmembrane transporter activity
LGQ02_RS20825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LGQ02_RS20830	COG0066	3-isopropylmalate dehydratase activity
LGQ02_RS20835	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGQ02_RS20840	COG0473	3-isopropylmalate dehydrogenase activity
LGQ02_RS20845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LGQ02_RS20850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LGQ02_RS20855	COG0440	acetolactate synthase activity
LGQ02_RS20860	COG0028	Belongs to the TPP enzyme family
LGQ02_RS20865	COG0129	dihydroxy-acid dehydratase activity
LGQ02_RS20880	COG3181	Tripartite tricarboxylate transporter family receptor
LGQ02_RS20895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGQ02_RS20900	COG0579	oxidoreductase
LGQ02_RS20905	COG1187	pseudouridine synthase activity
LGQ02_RS20915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGQ02_RS20925	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGQ02_RS20975	COG2003	Belongs to the UPF0758 family
LGQ02_RS20980	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGQ02_RS21000	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGQ02_RS21005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGQ02_RS21015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGQ02_RS21020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGQ02_RS21025	COG4853	Protein conserved in bacteria
LGQ02_RS21030	COG4863	YycH protein
LGQ02_RS21035	COG5002	protein histidine kinase activity
LGQ02_RS21040	COG0745	RESPONSE REGULATOR receiver
LGQ02_RS21045	COG0739	heme binding
LGQ02_RS21045	COG0741	lytic transglycosylase activity
LGQ02_RS21045	COG1196	nuclear chromosome segregation
LGQ02_RS21085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGQ02_RS21090	COG0305	Participates in initiation and elongation during chromosome replication
LGQ02_RS21095	COG0359	binds to the 23S rRNA
LGQ02_RS21100	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LGQ02_RS21115	COG5001	Diguanylate cyclase
LGQ02_RS21120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGQ02_RS21125	COG0629	single-stranded DNA binding
LGQ02_RS21130	COG0360	Binds together with S18 to 16S ribosomal RNA
LGQ02_RS21135	COG0012	GTP binding
LGQ02_RS21140	COG4481	Protein conserved in bacteria
LGQ02_RS21145	COG3949	Membrane
LGQ02_RS21160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGQ02_RS21165	COG1475	DNA binding
LGQ02_RS21170	COG1192	Involved in chromosome partitioning
LGQ02_RS21175	COG1475	DNA binding
LGQ02_RS21185	COG0445	tRNA wobble uridine modification
LGQ02_RS21190	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGQ02_RS21195	COG1847	R3H domain protein
LGQ02_RS21200	COG0706	membrane insertase activity
LGQ02_RS21215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGQ02_RS21300	COG4974	Belongs to the 'phage' integrase family
LGQ02_RS21305	COG4974	Belongs to the 'phage' integrase family