locus-tag	class	description
JD965_RS00010	COG0592	DNA-directed DNA polymerase activity
JD965_RS00015	COG2501	S4 domain
JD965_RS00030	COG0187	DNA topoisomerase II activity
JD965_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JD965_RS00070	COG0517	IMP dehydrogenase activity
JD965_RS00070	COG0516	GMP reductase activity
JD965_RS00075	COG1686	Belongs to the peptidase S11 family
JD965_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
JD965_RS00110	COG1428	Deoxynucleoside kinase
JD965_RS00115	COG1428	Deoxynucleoside kinase
JD965_RS00120	COG1388	LysM domain
JD965_RS00120	COG3858	chitin binding
JD965_RS00125	COG1335	isochorismatase
JD965_RS00130	COG0590	tRNA wobble adenosine to inosine editing
JD965_RS00140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JD965_RS00145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JD965_RS00195	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
JD965_RS00200	COG3853	Toxic anion resistance protein (TelA)
JD965_RS00205	COG1982	Orn Lys Arg decarboxylase major
JD965_RS00215	COG3870	Protein conserved in bacteria
JD965_RS00220	COG1728	Protein conserved in bacteria
JD965_RS00225	COG0470	DNA polymerase III
JD965_RS00230	COG1774	PSP1 C-terminal conserved region
JD965_RS00240	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JD965_RS00250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JD965_RS00255	COG2002	toxin-antitoxin pair type II binding
JD965_RS00260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JD965_RS00260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JD965_RS00265	COG0084	hydrolase, TatD family'
JD965_RS00270	COG3583	domain protein
JD965_RS00270	COG3584	3D domain protein
JD965_RS00275	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JD965_RS00280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JD965_RS00290	COG4466	Protein conserved in bacteria
JD965_RS00305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JD965_RS00310	COG0251	oxidation-reduction process
JD965_RS00325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JD965_RS00345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JD965_RS00350	COG2002	toxin-antitoxin pair type II binding
JD965_RS00355	COG2244	polysaccharide biosynthetic process
JD965_RS00360	COG3956	TIGRFAM MazG family protein
JD965_RS00365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JD965_RS00380	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JD965_RS00385	COG1098	S1 RNA binding domain
JD965_RS00400	COG2208	phosphoserine phosphatase activity
JD965_RS00405	COG2304	oxidoreductase activity
JD965_RS00410	COG0515	serine threonine protein kinase
JD965_RS00415	COG0037	tRNA processing
JD965_RS00420	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JD965_RS00425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JD965_RS00440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JD965_RS00445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JD965_RS00450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JD965_RS00455	COG0512	Glutamine amidotransferase of anthranilate synthase
JD965_RS00460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JD965_RS00465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JD965_RS00470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JD965_RS00475	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JD965_RS00480	COG1396	sequence-specific DNA binding
JD965_RS00485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JD965_RS00490	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JD965_RS00570	COG4463	regulation of RNA biosynthetic process
JD965_RS00575	COG3880	PFAM UvrB UvrC protein
JD965_RS00585	COG0542	response to heat
JD965_RS00590	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JD965_RS00595	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JD965_RS00600	COG4956	integral membrane protein (PIN domain superfamily)
JD965_RS00620	COG1045	serine acetyltransferase
JD965_RS00630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JD965_RS00635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JD965_RS00640	COG3688	RNA-binding protein containing a PIN domain
JD965_RS00645	COG1595	DNA-templated transcription, initiation
JD965_RS00655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JD965_RS00660	COG0250	Participates in transcription elongation, termination and antitermination
JD965_RS00670	COG0081	regulation of translation
JD965_RS00685	COG2813	Specifically methylates the guanine in position
JD965_RS00700	COG1358	cellular component organization or biogenesis
JD965_RS00725	COG0596	Alpha beta hydrolase
JD965_RS00820	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JD965_RS00835	COG0201	protein transport
JD965_RS00845	COG0024	Methionine aminopeptidase
JD965_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JD965_RS00880	COG1122	ATPase activity
JD965_RS00885	COG1122	ATPase activity
JD965_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JD965_RS00910	COG2226	methyltransferase
JD965_RS00915	COG2318	DinB family
JD965_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
JD965_RS00930	COG0489	protein tyrosine kinase activity
JD965_RS00940	COG2194	sulfuric ester hydrolase activity
JD965_RS00945	COG0726	polysaccharide deacetylase
JD965_RS01005	COG0738	Major facilitator superfamily
JD965_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JD965_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
JD965_RS01030	COG0385	Bile acid
JD965_RS01035	COG2819	hydrolase of the alpha beta superfamily
JD965_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JD965_RS01060	COG3876	Protein conserved in bacteria
JD965_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
JD965_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JD965_RS01075	COG1263	PTS System
JD965_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JD965_RS01090	COG1683	Conserved Protein
JD965_RS01120	COG1595	DNA-templated transcription, initiation
JD965_RS01125	COG5662	AntiSigma factor
JD965_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JD965_RS01135	COG4856	YbbR-like protein
JD965_RS01180	COG0596	Alpha beta hydrolase
JD965_RS01190	COG0642	Histidine kinase
JD965_RS01195	COG0515	serine threonine protein kinase
JD965_RS01205	COG1113	amino acid transport
JD965_RS01210	COG1011	Hydrolase
JD965_RS01220	COG2197	response regulator
JD965_RS01225	COG1131	(ABC) transporter
JD965_RS01235	COG0842	Transport permease protein
JD965_RS01235	COG1511	domain protein
JD965_RS01265	COG0531	amino acid
JD965_RS01270	COG0584	glycerophosphoryl diester phosphodiesterase
JD965_RS01275	COG2271	Major facilitator Superfamily
JD965_RS01285	COG2368	4-hydroxyphenylacetate
JD965_RS01305	COG0371	Dehydrogenase
JD965_RS01315	COG1183	phosphatidylcholine synthase activity
JD965_RS01320	COG0586	Pfam SNARE associated Golgi protein
JD965_RS01325	COG0688	phosphatidylethanolamine metabolic process
JD965_RS01340	COG1301	dicarboxylic acid transport
JD965_RS01345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JD965_RS01350	COG0833	amino acid
JD965_RS01355	COG2040	homocysteine
JD965_RS01360	COG1115	amino acid carrier protein
JD965_RS01365	COG2066	Belongs to the glutaminase family
JD965_RS01370	COG4191	Histidine kinase
JD965_RS01375	COG0784	Response regulator, receiver
JD965_RS01380	COG3173	Aminoglycoside phosphotransferase
JD965_RS01390	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JD965_RS01395	COG0778	Nitroreductase
JD965_RS01400	COG0346	lactoylglutathione lyase activity
JD965_RS01405	COG2259	Doxx family
JD965_RS01410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS01420	COG3773	Cell wall hydrolase
JD965_RS01425	COG3540	Alkaline phosphatase
JD965_RS01430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JD965_RS01435	COG0805	protein transport
JD965_RS01440	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JD965_RS01445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JD965_RS01450	COG0477	Major facilitator Superfamily
JD965_RS01455	COG1309	transcriptional regulator
JD965_RS01460	COG0252	asparaginase activity
JD965_RS01465	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JD965_RS01470	COG3012	SEC-C Motif Domain Protein
JD965_RS01470	COG1405	negative regulation of cell septum assembly
JD965_RS01475	COG0667	Aldo Keto reductase
JD965_RS01485	COG1595	DNA-templated transcription, initiation
JD965_RS01490	COG1595	DNA-templated transcription, initiation
JD965_RS01495	COG1876	peptidase activity
JD965_RS01500	COG0457	Tetratricopeptide repeat
JD965_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS01510	COG0366	Alpha amylase catalytic
JD965_RS01515	COG0803	Belongs to the bacterial solute-binding protein 9 family
JD965_RS01520	COG1121	(ABC) transporter
JD965_RS01525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JD965_RS01530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS01535	COG2310	stress, protein
JD965_RS01540	COG2310	stress, protein
JD965_RS01545	COG2310	stress, protein
JD965_RS01550	COG0861	Integral membrane protein TerC family
JD965_RS01560	COG3853	Toxic anion resistance protein (TelA)
JD965_RS01565	COG0477	Major facilitator Superfamily
JD965_RS01570	COG4175	Glycine betaine
JD965_RS01570	COG0517	IMP dehydrogenase activity
JD965_RS01575	COG4176	ABC-type proline glycine betaine transport system permease component
JD965_RS01580	COG2113	Glycine betaine
JD965_RS01585	COG1473	amidohydrolase
JD965_RS01590	COG1288	antiporter activity
JD965_RS01600	COG0366	Alpha amylase catalytic
JD965_RS01610	COG2814	Major facilitator Superfamily
JD965_RS01615	COG1846	Transcriptional regulator
JD965_RS01620	COG1280	lysine exporter protein (LysE YggA)
JD965_RS01625	COG3403	YqcI/YcgG family
JD965_RS01630	COG1113	amino acid transport
JD965_RS01635	COG3665	Urea carboxylase-associated protein
JD965_RS01645	COG1082	Xylose isomerase domain protein TIM barrel
JD965_RS01650	COG2271	Major facilitator Superfamily
JD965_RS01655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JD965_RS01660	COG3458	cephalosporin-C deacetylase activity
JD965_RS01665	COG3541	Predicted nucleotidyltransferase
JD965_RS01670	COG0506	proline dehydrogenase activity
JD965_RS01675	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS01680	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JD965_RS01685	COG2508	Transcriptional regulator
JD965_RS01695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JD965_RS01695	COG1587	Uroporphyrinogen-III synthase
JD965_RS01700	COG2146	nitrite reductase [NAD(P)H] activity
JD965_RS01705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JD965_RS01710	COG0523	cobalamin synthesis protein
JD965_RS01715	COG1063	alcohol dehydrogenase
JD965_RS01720	COG1714	RDD family
JD965_RS01740	COG3209	COG3209 Rhs family protein
JD965_RS01745	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JD965_RS01750	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
JD965_RS01755	COG1733	regulation of RNA biosynthetic process
JD965_RS01760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS01765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS01770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS01775	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JD965_RS01795	COG2364	Membrane
JD965_RS01800	COG1126	abc transporter atp-binding protein
JD965_RS01805	COG0765	amino acid transport
JD965_RS01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JD965_RS01815	COG0583	DNA-binding transcription factor activity
JD965_RS01820	COG0163	prenyltransferase activity
JD965_RS01825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JD965_RS01840	COG3104	oligopeptide transport
JD965_RS01855	COG0697	spore germination
JD965_RS01865	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JD965_RS01870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS01875	COG0456	acetyltransferase
JD965_RS01885	COG0765	amino acid transport
JD965_RS01890	COG1126	abc transporter atp-binding protein
JD965_RS01895	COG1473	amidohydrolase
JD965_RS01900	COG2079	MmgE PrpD family protein
JD965_RS01905	COG1136	(ABC) transporter
JD965_RS01910	COG0577	efflux transmembrane transporter activity
JD965_RS01915	COG0745	RESPONSE REGULATOR receiver
JD965_RS01920	COG3850	Histidine kinase
JD965_RS01920	COG5002	protein histidine kinase activity
JD965_RS01925	COG0457	Tetratricopeptide repeat
JD965_RS01940	COG0527	aspartate kinase activity
JD965_RS01945	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS01950	COG4605	iron ion homeostasis
JD965_RS01955	COG4604	ABC transporter, ATP-binding protein
JD965_RS01960	COG4607	ABC-type enterochelin transport system periplasmic component
JD965_RS01965	COG2814	Major facilitator Superfamily
JD965_RS01970	COG1309	transcriptional regulator
JD965_RS01975	COG0778	Nitroreductase
JD965_RS01980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JD965_RS01985	COG0640	Transcriptional regulator
JD965_RS01990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JD965_RS01995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JD965_RS02000	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS02005	COG4975	Glucose uptake
JD965_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS02015	COG4549	nuclear export factor GLE1
JD965_RS02020	COG2372	response to copper ion
JD965_RS02020	COG1276	copper resistance
JD965_RS02025	COG1349	DNA-binding transcription factor activity
JD965_RS02035	COG2213	PTS system mannitol-specific
JD965_RS02040	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JD965_RS02050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JD965_RS02060	COG0561	phosphatase activity
JD965_RS02070	COG1914	H( )-stimulated, divalent metal cation uptake system
JD965_RS02080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JD965_RS02085	COG1984	allophanate hydrolase subunit 2
JD965_RS02090	COG1414	Transcriptional regulator
JD965_RS02095	COG2755	lipolytic protein G-D-S-L family
JD965_RS02105	COG2329	Antibiotic biosynthesis monooxygenase
JD965_RS02110	COG0768	penicillin binding
JD965_RS02120	COG3711	transcriptional antiterminator
JD965_RS02125	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS02130	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS02135	COG1917	Cupin 2, conserved barrel domain protein
JD965_RS02140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JD965_RS02145	COG3871	stress protein (general stress protein 26)
JD965_RS02155	COG2814	Major facilitator Superfamily
JD965_RS02160	COG1522	sequence-specific DNA binding
JD965_RS02165	COG0551	DNA topoisomerase type I activity
JD965_RS02165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JD965_RS02170	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JD965_RS02175	COG3706	GGDEF domain
JD965_RS02180	COG5298	Protein conserved in bacteria
JD965_RS02185	COG1215	transferase activity, transferring glycosyl groups
JD965_RS02195	COG0531	amino acid
JD965_RS02200	COG0494	nUDIX hydrolase
JD965_RS02205	COG0028	Belongs to the TPP enzyme family
JD965_RS02245	COG1914	H( )-stimulated, divalent metal cation uptake system
JD965_RS02255	COG4876	unkown
JD965_RS02265	COG2076	Multidrug Resistance protein
JD965_RS02270	COG2217	Heavy metal translocating P-type atpase
JD965_RS02275	COG3729	General stress protein
JD965_RS02280	COG0662	Cupin 2, conserved barrel domain protein
JD965_RS02285	COG2329	Antibiotic biosynthesis monooxygenase
JD965_RS02295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JD965_RS02300	COG3290	protein histidine kinase activity
JD965_RS02305	COG4565	transcriptional regulatory protein
JD965_RS02310	COG1301	dicarboxylic acid transport
JD965_RS02315	COG0628	permease
JD965_RS02320	COG1131	(ABC) transporter
JD965_RS02325	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JD965_RS02335	COG1960	acyl-CoA dehydrogenase activity
JD965_RS02350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JD965_RS02355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS02365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JD965_RS02370	COG0513	Belongs to the DEAD box helicase family
JD965_RS02375	COG3402	PFAM membrane-flanked domain
JD965_RS02380	COG3428	Bacterial PH domain
JD965_RS02385	COG0705	Rhomboid family
JD965_RS02395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JD965_RS02400	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JD965_RS02405	COG0864	Transcriptional regulator
JD965_RS02410	COG2337	Toxic component of a toxin-antitoxin (TA) module
JD965_RS02415	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS02420	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS02425	COG2172	sigma factor antagonist activity
JD965_RS02430	COG2208	phosphoserine phosphatase activity
JD965_RS02435	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS02445	COG1191	sigma factor activity
JD965_RS02450	COG2208	phosphoserine phosphatase activity
JD965_RS02455	COG2183	response to ionizing radiation
JD965_RS02525	COG0697	spore germination
JD965_RS02550	COG1959	2 iron, 2 sulfur cluster binding
JD965_RS02570	COG2249	NAD(P)H dehydrogenase (quinone) activity
JD965_RS02600	COG0477	Major facilitator Superfamily
JD965_RS02610	COG1764	response to oxidative stress
JD965_RS02615	COG1846	Transcriptional regulator
JD965_RS02625	COG1959	2 iron, 2 sulfur cluster binding
JD965_RS02630	COG2910	NAD(P)H-binding
JD965_RS02640	COG1278	Cold shock
JD965_RS02645	COG1329	Transcriptional regulator
JD965_RS02650	COG2188	Transcriptional regulator
JD965_RS02655	COG1447	Phosphotransferase system cellobiose-specific component IIA
JD965_RS02665	COG2723	6-phospho-beta-galactosidase activity
JD965_RS02670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS02675	COG1940	carbohydrate kinase activity
JD965_RS02685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JD965_RS02690	COG0531	amino acid
JD965_RS02695	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JD965_RS02700	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JD965_RS02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JD965_RS02720	COG1794	racemase activity, acting on amino acids and derivatives
JD965_RS02735	COG0456	acetyltransferase
JD965_RS02735	COG1846	Transcriptional regulator
JD965_RS02740	COG2271	Major facilitator Superfamily
JD965_RS02745	COG3621	Patatin-like phospholipase
JD965_RS02755	COG0662	Cupin 2, conserved barrel domain protein
JD965_RS02775	COG0277	FAD linked oxidase domain protein
JD965_RS02795	COG0662	Cupin 2, conserved barrel domain protein
JD965_RS02800	COG0456	acetyltransferase
JD965_RS02805	COG2318	DinB family
JD965_RS02825	COG0789	Transcriptional regulator
JD965_RS02835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JD965_RS02850	COG3963	phosphatidate phosphatase activity
JD965_RS02860	COG5002	protein histidine kinase activity
JD965_RS02870	COG2814	Major facilitator Superfamily
JD965_RS02875	COG1309	transcriptional regulator
JD965_RS02885	COG5577	PFAM Coat F domain
JD965_RS02895	COG1063	alcohol dehydrogenase
JD965_RS02900	COG5577	PFAM Coat F domain
JD965_RS02910	COG4585	Histidine kinase
JD965_RS02915	COG2197	response regulator
JD965_RS02920	COG2409	Drug exporters of the RND superfamily
JD965_RS02925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JD965_RS02930	COG0488	(ABC) transporter
JD965_RS02935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JD965_RS02940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS02950	COG2814	Major facilitator Superfamily
JD965_RS02955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JD965_RS02965	COG0730	response to heat
JD965_RS02970	COG0456	acetyltransferase
JD965_RS02975	COG1051	belongs to the nudix hydrolase family
JD965_RS02980	COG0596	Alpha beta hydrolase
JD965_RS02985	COG0473	3-isopropylmalate dehydrogenase activity
JD965_RS02990	COG1802	Transcriptional regulator
JD965_RS02995	COG1819	glycosyl
JD965_RS03010	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JD965_RS03020	COG1388	LysM domain
JD965_RS03025	COG2814	Major facilitator Superfamily
JD965_RS03030	COG2188	Transcriptional regulator
JD965_RS03035	COG2186	Transcriptional regulator
JD965_RS03040	COG2807	transmembrane transport
JD965_RS03045	COG2076	Multidrug Resistance protein
JD965_RS03050	COG2076	Multidrug Resistance protein
JD965_RS03055	COG1309	transcriptional regulator
JD965_RS03060	COG0531	amino acid
JD965_RS03070	COG3832	glyoxalase III activity
JD965_RS03075	COG0604	alcohol dehydrogenase
JD965_RS03080	COG2814	Major facilitator Superfamily
JD965_RS03120	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JD965_RS03125	COG0802	atpase or kinase
JD965_RS03135	COG0456	acetyltransferase
JD965_RS03140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JD965_RS03145	COG0488	(ABC) transporter
JD965_RS03160	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JD965_RS03165	COG0805	protein transport
JD965_RS03175	COG1266	CAAX protease self-immunity
JD965_RS03195	COG2856	Zn peptidase
JD965_RS03210	COG1396	sequence-specific DNA binding
JD965_RS03280	COG3935	DnaD domain protein
JD965_RS03285	COG1484	DNA-dependent DNA replication
JD965_RS03295	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
JD965_RS03365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JD965_RS03380	COG2337	Toxic component of a toxin-antitoxin (TA) module
JD965_RS03390	COG4980	gas vesicle protein
JD965_RS03390	COG1674	ftsk spoiiie
JD965_RS03410	COG4626	Terminase
JD965_RS03410	COG1802	Transcriptional regulator
JD965_RS03470	COG5280	Phage tail tape measure protein TP901
JD965_RS03470	COG3953	SLT domain
JD965_RS03480	COG1705	Flagellar rod assembly protein muramidase FlgJ
JD965_RS03505	COG4824	toxin secretion phage lysis holin
JD965_RS03520	COG0156	8-amino-7-oxononanoate synthase activity
JD965_RS03540	COG3403	YqcI/YcgG family
JD965_RS03555	COG2814	Major facilitator Superfamily
JD965_RS03560	COG0457	Tetratricopeptide repeat
JD965_RS03565	COG1063	alcohol dehydrogenase
JD965_RS03570	COG2211	Major facilitator Superfamily
JD965_RS03575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JD965_RS03585	COG1842	Phage shock protein A
JD965_RS03590	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JD965_RS03595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JD965_RS03600	COG4260	virion core protein, lumpy skin disease virus
JD965_RS03610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
JD965_RS03610	COG2755	lipolytic protein G-D-S-L family
JD965_RS03620	COG1595	DNA-templated transcription, initiation
JD965_RS03625	COG1063	alcohol dehydrogenase
JD965_RS03630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JD965_RS03635	COG0823	Involved in the tonB-independent uptake of proteins
JD965_RS03655	COG2132	Multicopper oxidase
JD965_RS03660	COG1113	amino acid transport
JD965_RS03665	COG0714	Associated with various cellular activities
JD965_RS03670	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
JD965_RS03675	COG1305	Transglutaminase-like
JD965_RS03685	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JD965_RS03705	COG2211	Major facilitator Superfamily
JD965_RS03725	COG2252	PERMEase
JD965_RS03730	COG3064	Membrane
JD965_RS03750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JD965_RS03755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JD965_RS03760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JD965_RS03765	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JD965_RS03770	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JD965_RS03785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JD965_RS03795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JD965_RS03800	COG0138	bifunctional purine biosynthesis protein purh
JD965_RS03805	COG0151	Belongs to the GarS family
JD965_RS03815	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JD965_RS03820	COG1470	cell adhesion involved in biofilm formation
JD965_RS03825	COG4496	protein, YerC YecD
JD965_RS03830	COG0069	glutamate synthase activity
JD965_RS03840	COG0210	DNA helicase
JD965_RS03850	COG4851	CamS sex pheromone cAM373 precursor
JD965_RS03855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JD965_RS03860	COG1285	pathogenesis
JD965_RS03870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JD965_RS03890	COG1309	transcriptional regulator
JD965_RS03895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JD965_RS03900	COG1597	lipid kinase activity
JD965_RS03905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JD965_RS03910	COG1136	(ABC) transporter
JD965_RS03920	COG1131	(ABC) transporter
JD965_RS03950	COG3546	catalase activity
JD965_RS03965	COG2323	membrane
JD965_RS03975	COG2329	Antibiotic biosynthesis monooxygenase
JD965_RS03980	COG0346	lactoylglutathione lyase activity
JD965_RS03985	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS03990	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JD965_RS03995	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JD965_RS04000	COG4208	sulfate ABC transporter
JD965_RS04010	COG5583	Uncharacterized small protein (DUF2292)
JD965_RS04015	COG0196	riboflavin kinase activity
JD965_RS04020	COG0670	Belongs to the BI1 family
JD965_RS04025	COG1846	Transcriptional regulator
JD965_RS04030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JD965_RS04040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JD965_RS04040	COG2124	cytochrome p450
JD965_RS04055	COG1131	(ABC) transporter
JD965_RS04065	COG1368	sulfuric ester hydrolase activity
JD965_RS04070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JD965_RS04075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JD965_RS04080	COG1442	glycosyl transferase family 8
JD965_RS04085	COG1216	Glycosyl transferase, family 2
JD965_RS04090	COG1442	glycosyl transferase family 8
JD965_RS04095	COG2223	nitrite transmembrane transporter activity
JD965_RS04100	COG0531	amino acid
JD965_RS04105	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS04110	COG0840	transmembrane signaling receptor activity
JD965_RS04115	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS04155	COG0457	Tetratricopeptide repeat
JD965_RS04170	COG1695	Transcriptional regulator
JD965_RS04190	COG0577	efflux transmembrane transporter activity
JD965_RS04190	COG1136	(ABC) transporter
JD965_RS04215	COG0463	Glycosyl transferase, family 2
JD965_RS04215	COG0457	Tetratricopeptide repeat
JD965_RS04220	COG0488	(ABC) transporter
JD965_RS04225	COG0789	Transcriptional regulator
JD965_RS04230	COG2814	Major facilitator Superfamily
JD965_RS04235	COG0488	(ABC) transporter
JD965_RS04240	COG0513	Belongs to the DEAD box helicase family
JD965_RS04245	COG0456	acetyltransferase
JD965_RS04250	COG2130	NADP-dependent
JD965_RS04265	COG3866	Pectate lyase
JD965_RS04270	COG0471	metal ion transport
JD965_RS04290	COG3290	protein histidine kinase activity
JD965_RS04295	COG4565	transcriptional regulatory protein
JD965_RS04300	COG3181	Tripartite tricarboxylate transporter family receptor
JD965_RS04305	COG2851	Citrate transporter
JD965_RS04310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS04315	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JD965_RS04325	COG2258	MOSC domain
JD965_RS04345	COG0024	Methionine aminopeptidase
JD965_RS04350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS04350	COG1263	PTS System
JD965_RS04360	COG1368	sulfuric ester hydrolase activity
JD965_RS04370	COG0071	Belongs to the small heat shock protein (HSP20) family
JD965_RS04385	COG0778	Nitroreductase
JD965_RS04400	COG0737	Belongs to the 5'-nucleotidase family
JD965_RS04405	COG0693	protein deglycase activity
JD965_RS04410	COG1609	Transcriptional regulator
JD965_RS04425	COG2814	Major facilitator Superfamily
JD965_RS04435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JD965_RS04440	COG4980	gas vesicle protein
JD965_RS04445	COG1295	ribonuclease BN
JD965_RS04450	COG0477	Major facilitator Superfamily
JD965_RS04455	COG0387	Pfam Sodium calcium exchanger
JD965_RS04465	COG0668	transmembrane transport
JD965_RS04470	COG0535	radical SAM domain protein
JD965_RS04480	COG0726	polysaccharide deacetylase
JD965_RS04500	COG0745	RESPONSE REGULATOR receiver
JD965_RS04505	COG2205	protein histidine kinase activity
JD965_RS04510	COG2084	Dehydrogenase
JD965_RS04520	COG0598	Magnesium transport protein CorA
JD965_RS04525	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JD965_RS04530	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JD965_RS04540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JD965_RS04545	COG4637	Psort location Cytoplasmic, score
JD965_RS04550	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JD965_RS04555	COG0022	dehydrogenase e1 component
JD965_RS04560	COG0508	dehydrogenase complex catalyzes the overall conversion of
JD965_RS04565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JD965_RS04570	COG3284	Transcriptional regulator
JD965_RS04580	COG1486	melibiose metabolic process
JD965_RS04585	COG1737	Transcriptional regulator
JD965_RS04590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS04590	COG1263	PTS System
JD965_RS04595	COG5434	Belongs to the glycosyl hydrolase 28 family
JD965_RS04600	COG1132	(ABC) transporter
JD965_RS04605	COG1132	(ABC) transporter
JD965_RS04610	COG2259	Doxx family
JD965_RS04615	COG2514	catechol 2,3-dioxygenase activity
JD965_RS04625	COG1695	Transcriptional regulator
JD965_RS04630	COG2249	NAD(P)H dehydrogenase (quinone) activity
JD965_RS04635	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JD965_RS04640	COG2732	(Barnase) inhibitor
JD965_RS04645	COG2318	DinB family
JD965_RS04650	COG2814	Major facilitator Superfamily
JD965_RS04655	COG1846	Transcriptional regulator
JD965_RS04660	COG0392	lysyltransferase activity
JD965_RS04660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JD965_RS04670	COG0384	phenazine biosynthesis protein PhzF
JD965_RS04675	COG0778	Nitroreductase
JD965_RS04690	COG1090	epimerase
JD965_RS04705	COG2814	Major facilitator Superfamily
JD965_RS04720	COG3103	Sh3 type 3 domain protein
JD965_RS04725	COG5658	integral membrane protein
JD965_RS04730	COG0596	Alpha beta hydrolase
JD965_RS04735	COG0463	Glycosyl transferase, family 2
JD965_RS04740	COG4485	Bacterial membrane protein, YfhO
JD965_RS04745	COG1988	membrane-bound metal-dependent
JD965_RS04750	COG1194	a g-specific adenine glycosylase
JD965_RS04760	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS04780	COG1132	(ABC) transporter
JD965_RS04785	COG4129	membrane
JD965_RS04795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JD965_RS04800	COG0735	belongs to the Fur family
JD965_RS04950	COG5577	PFAM Coat F domain
JD965_RS04955	COG3340	Belongs to the peptidase S51 family
JD965_RS04960	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JD965_RS04965	COG0277	FAD linked oxidase domain protein
JD965_RS04975	COG4166	transmembrane transport
JD965_RS04980	COG0601	transmembrane transport
JD965_RS04985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JD965_RS04990	COG0444	Belongs to the ABC transporter superfamily
JD965_RS04995	COG4608	Belongs to the ABC transporter superfamily
JD965_RS05000	COG0753	catalase activity
JD965_RS05010	COG1116	anion transmembrane transporter activity
JD965_RS05015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JD965_RS05020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JD965_RS05045	COG1476	TRANSCRIPTIONal
JD965_RS05055	COG3382	B3 4 domain protein
JD965_RS05060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JD965_RS05070	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JD965_RS05075	COG0789	Transcriptional regulator
JD965_RS05080	COG1664	Polymer-forming cytoskeletal
JD965_RS05085	COG1664	Polymer-forming cytoskeletal
JD965_RS05090	COG2766	serine protein kinase
JD965_RS05100	COG1846	Transcriptional regulator
JD965_RS05105	COG1566	PFAM secretion protein HlyD family protein
JD965_RS05110	COG2814	Major facilitator Superfamily
JD965_RS05115	COG0655	NAD(P)H dehydrogenase (quinone) activity
JD965_RS05130	COG1725	Transcriptional regulator
JD965_RS05135	COG1131	(ABC) transporter
JD965_RS05140	COG1131	(ABC) transporter
JD965_RS05145	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
JD965_RS05150	COG1278	Cold shock
JD965_RS05160	COG3706	GGDEF domain
JD965_RS05165	COG1823	symporter activity
JD965_RS05185	COG5577	PFAM Coat F domain
JD965_RS05195	COG3764	Sortase (surface protein transpeptidase)
JD965_RS05200	COG0564	pseudouridine synthase activity
JD965_RS05210	COG0517	IMP dehydrogenase activity
JD965_RS05215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JD965_RS05220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JD965_RS05220	COG3153	acetyltransferase
JD965_RS05225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JD965_RS05230	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JD965_RS05235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JD965_RS05245	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JD965_RS05250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JD965_RS05255	COG4585	Histidine kinase
JD965_RS05255	COG2203	Gaf domain
JD965_RS05260	COG2197	response regulator
JD965_RS05265	COG0431	NADPH-dependent FMN reductase
JD965_RS05280	COG0791	NLP P60 protein
JD965_RS05280	COG1388	LysM domain
JD965_RS05285	COG1959	2 iron, 2 sulfur cluster binding
JD965_RS05290	COG0668	transmembrane transport
JD965_RS05295	COG2719	SpoVR family
JD965_RS05300	COG1785	Belongs to the alkaline phosphatase family
JD965_RS05305	COG0791	NLP P60 protein
JD965_RS05305	COG1388	LysM domain
JD965_RS05310	COG0583	DNA-binding transcription factor activity
JD965_RS05315	COG0372	Belongs to the citrate synthase family
JD965_RS05320	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS05325	COG0531	amino acid
JD965_RS05330	COG0733	neurotransmitter:sodium symporter activity
JD965_RS05345	COG1595	DNA-templated transcription, initiation
JD965_RS05350	COG0204	Acyl-transferase
JD965_RS05355	COG1253	flavin adenine dinucleotide binding
JD965_RS05360	COG0789	Transcriptional regulator
JD965_RS05365	COG0436	Aminotransferase
JD965_RS05370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JD965_RS05375	COG1253	flavin adenine dinucleotide binding
JD965_RS05380	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JD965_RS05385	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JD965_RS05390	COG0584	glycerophosphoryl diester phosphodiesterase
JD965_RS05400	COG0668	transmembrane transport
JD965_RS05405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JD965_RS05410	COG0726	polysaccharide deacetylase
JD965_RS05415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JD965_RS05420	COG3226	Transcriptional regulator
JD965_RS05430	COG0589	response to stress
JD965_RS05435	COG1132	(ABC) transporter
JD965_RS05440	COG1132	(ABC) transporter
JD965_RS05445	COG0702	epimerase
JD965_RS05460	COG0189	ligase activity
JD965_RS05465	COG0189	ligase activity
JD965_RS05480	COG4335	DNA alkylation repair
JD965_RS05485	COG0561	phosphatase activity
JD965_RS05490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JD965_RS05500	COG0475	glutathione-regulated potassium exporter activity
JD965_RS05505	COG0490	domain, Protein
JD965_RS05515	COG1024	Enoyl-CoA hydratase
JD965_RS05525	COG4152	abc transporter atp-binding protein
JD965_RS05530	COG1668	transmembrane transport
JD965_RS05535	COG0420	3'-5' exonuclease activity
JD965_RS05540	COG4717	serine-type aminopeptidase activity
JD965_RS05555	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JD965_RS05590	COG4980	gas vesicle protein
JD965_RS05605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JD965_RS05610	COG0537	adenosine 5'-monophosphoramidase activity
JD965_RS05615	COG1131	(ABC) transporter
JD965_RS05620	COG4473	ABC transporter
JD965_RS05630	COG1473	amidohydrolase
JD965_RS05635	COG3069	C4-dicarboxylate transmembrane transporter activity
JD965_RS05640	COG2329	Antibiotic biosynthesis monooxygenase
JD965_RS05645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JD965_RS05655	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JD965_RS05660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JD965_RS05665	COG1309	transcriptional regulator
JD965_RS05670	COG1511	domain protein
JD965_RS05675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JD965_RS05685	COG1363	Peptidase, m42
JD965_RS05690	COG1301	dicarboxylic acid transport
JD965_RS05700	COG1234	tRNA 3'-trailer cleavage
JD965_RS05705	COG0095	Lipoate-protein ligase
JD965_RS05710	COG0702	epimerase
JD965_RS05715	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS05725	COG0501	Belongs to the peptidase M48B family
JD965_RS05730	COG1404	Belongs to the peptidase S8 family
JD965_RS05735	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JD965_RS05740	COG0406	alpha-ribazole phosphatase activity
JD965_RS05745	COG0183	Belongs to the thiolase family
JD965_RS05750	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS05755	COG1268	BioY protein
JD965_RS05760	COG0840	transmembrane signaling receptor activity
JD965_RS05765	COG0723	plastoquinol--plastocyanin reductase activity
JD965_RS05765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JD965_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS05780	COG4903	ComK protein
JD965_RS05785	COG5646	InterPro IPR014922
JD965_RS05820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JD965_RS05835	COG0398	Pfam SNARE associated Golgi protein
JD965_RS05840	COG0681	Belongs to the peptidase S26 family
JD965_RS05845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JD965_RS05850	COG1846	Transcriptional regulator
JD965_RS05860	COG3180	Ammonia monooxygenase
JD965_RS05865	COG2814	Major facilitator Superfamily
JD965_RS05875	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
JD965_RS05880	COG2323	membrane
JD965_RS05895	COG0420	3'-5' exonuclease activity
JD965_RS05900	COG0419	ATPase involved in DNA repair
JD965_RS05905	COG1403	HNH endonuclease
JD965_RS05945	COG0179	Fumarylacetoacetate (FAA) hydrolase
JD965_RS05960	COG0367	asparagine synthase
JD965_RS05965	COG1562	ergosterol biosynthetic process
JD965_RS05970	COG0534	Mate efflux family protein
JD965_RS05975	COG1917	Cupin 2, conserved barrel domain protein
JD965_RS05975	COG2207	Transcriptional regulator
JD965_RS05980	COG2318	DinB family
JD965_RS05985	COG1279	arginine transmembrane transporter activity
JD965_RS05990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JD965_RS05995	COG1357	PFAM Pentapeptide repeats (8 copies)
JD965_RS06000	COG2153	protein acetylation
JD965_RS06005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JD965_RS06005	COG0646	methionine synthase
JD965_RS06015	COG2996	Protein conserved in bacteria
JD965_RS06025	COG1307	EDD domain protein, DegV family
JD965_RS06030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS06050	COG0561	phosphatase activity
JD965_RS06055	COG1073	alpha beta
JD965_RS06060	COG2151	metal-sulfur cluster biosynthetic enzyme
JD965_RS06070	COG0277	FAD linked oxidase domain protein
JD965_RS06075	COG2271	Major facilitator Superfamily
JD965_RS06085	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JD965_RS06095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JD965_RS06100	COG0505	Belongs to the CarA family
JD965_RS06105	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JD965_RS06110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JD965_RS06130	COG2267	carboxylic ester hydrolase activity
JD965_RS06140	COG1744	ABC transporter substrate-binding protein PnrA-like
JD965_RS06155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JD965_RS06160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JD965_RS06165	COG5504	Zn-dependent protease
JD965_RS06170	COG0444	Belongs to the ABC transporter superfamily
JD965_RS06175	COG4608	Belongs to the ABC transporter superfamily
JD965_RS06185	COG0601	transmembrane transport
JD965_RS06190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JD965_RS06200	COG0180	Tryptophanyl-tRNA synthetase
JD965_RS06205	COG4166	transmembrane transport
JD965_RS06210	COG0601	transmembrane transport
JD965_RS06215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JD965_RS06220	COG0444	Belongs to the ABC transporter superfamily
JD965_RS06225	COG4608	Belongs to the ABC transporter superfamily
JD965_RS06235	COG0456	acetyltransferase
JD965_RS06240	COG1393	Belongs to the ArsC family
JD965_RS06250	COG0861	Integral membrane protein TerC family
JD965_RS06260	COG4862	establishment of competence for transformation
JD965_RS06265	COG4469	Competence protein
JD965_RS06270	COG1164	Oligoendopeptidase f
JD965_RS06280	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JD965_RS06285	COG2346	COG2346, Truncated hemoglobins
JD965_RS06290	COG0741	lytic transglycosylase activity
JD965_RS06295	COG4116	CYTH
JD965_RS06305	COG2357	RelA SpoT domain protein
JD965_RS06310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JD965_RS06315	COG0564	pseudouridine synthase activity
JD965_RS06325	COG0569	domain protein
JD965_RS06325	COG0475	glutathione-regulated potassium exporter activity
JD965_RS06330	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JD965_RS06335	COG0352	thiamine-phosphate diphosphorylase activity
JD965_RS06340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JD965_RS06345	COG2104	thiamine diphosphate biosynthetic process
JD965_RS06355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JD965_RS06360	COG0351	phosphomethylpyrimidine kinase
JD965_RS06365	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JD965_RS06420	COG0210	DNA helicase
JD965_RS06440	COG1131	(ABC) transporter
JD965_RS06450	COG2153	protein acetylation
JD965_RS06460	COG2382	esterase
JD965_RS06465	COG0626	cystathionine gamma-synthase activity
JD965_RS06470	COG0626	cystathionine gamma-synthase activity
JD965_RS06605	COG2367	Beta-lactamase
JD965_RS06610	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JD965_RS06615	COG2814	Major facilitator Superfamily
JD965_RS06630	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JD965_RS06635	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JD965_RS06640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JD965_RS06645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS06645	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS06650	COG1447	Phosphotransferase system cellobiose-specific component IIA
JD965_RS06655	COG2723	6-phospho-beta-galactosidase activity
JD965_RS06660	COG1349	DNA-binding transcription factor activity
JD965_RS06680	COG1285	pathogenesis
JD965_RS06690	COG2205	protein histidine kinase activity
JD965_RS06700	COG3383	formate dehydrogenase (NAD+) activity
JD965_RS06705	COG2427	Protein of unknown function (DUF1641)
JD965_RS06710	COG2124	cytochrome p450
JD965_RS06715	COG1819	glycosyl
JD965_RS06725	COG1587	Uroporphyrinogen-III synthase
JD965_RS06730	COG0390	transport system, permease component
JD965_RS06735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JD965_RS06740	COG0697	spore germination
JD965_RS06755	COG1252	NADH dehydrogenase
JD965_RS06765	COG1609	Transcriptional regulator
JD965_RS06770	COG0745	RESPONSE REGULATOR receiver
JD965_RS06775	COG2205	protein histidine kinase activity
JD965_RS06775	COG2770	Histidine kinase
JD965_RS06785	COG0730	response to heat
JD965_RS06790	COG2318	DinB family
JD965_RS06795	COG0457	Tetratricopeptide repeat
JD965_RS06810	COG5632	N-Acetylmuramoyl-L-alanine amidase
JD965_RS06810	COG1388	LysM domain
JD965_RS06810	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS06820	COG4195	phage-related replication protein
JD965_RS06825	COG2856	Zn peptidase
JD965_RS06830	COG1396	sequence-specific DNA binding
JD965_RS06845	COG1484	DNA-dependent DNA replication
JD965_RS06865	COG1595	DNA-templated transcription, initiation
JD965_RS06870	COG5484	DNA packaging
JD965_RS06870	COG3728	DNA packaging
JD965_RS06875	COG1783	phage Terminase large subunit
JD965_RS06880	COG5518	Phage portal protein
JD965_RS06885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JD965_RS06890	COG4653	Phage capsid family
JD965_RS06940	COG5412	phage tail tape measure protein
JD965_RS06940	COG3953	SLT domain
JD965_RS06940	COG5412	phage tail tape measure protein
JD965_RS06940	COG5412	phage tail tape measure protein
JD965_RS06940	COG3953	SLT domain
JD965_RS06940	COG3953	SLT domain
JD965_RS06945	COG1652	LysM domain
JD965_RS06950	COG4193	domain, Protein
JD965_RS06960	COG3628	GPW Gp25 family protein
JD965_RS06965	COG3299	homolog of phage Mu protein gp47
JD965_RS06970	COG3778	Protein conserved in bacteria
JD965_RS07010	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS07010	COG5632	N-Acetylmuramoyl-L-alanine amidase
JD965_RS07030	COG0306	phosphate transporter
JD965_RS07035	COG1392	Phosphate transport regulator
JD965_RS07040	COG0531	amino acid
JD965_RS07045	COG0346	lactoylglutathione lyase activity
JD965_RS07050	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JD965_RS07055	COG0463	Glycosyl transferase, family 2
JD965_RS07065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JD965_RS07070	COG0477	Major facilitator Superfamily
JD965_RS07075	COG2362	D-Aminopeptidase
JD965_RS07080	COG0601	transmembrane transport
JD965_RS07085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JD965_RS07090	COG0444	Belongs to the ABC transporter superfamily
JD965_RS07095	COG4166	transmembrane transport
JD965_RS07100	COG1619	proteins homologs of microcin C7 resistance protein MccF
JD965_RS07105	COG4948	Mandelate Racemase Muconate Lactonizing
JD965_RS07110	COG0791	NLP P60 protein
JD965_RS07115	COG4608	Belongs to the ABC transporter superfamily
JD965_RS07120	COG2706	6-phosphogluconolactonase activity
JD965_RS07125	COG1834	amidinotransferase
JD965_RS07130	COG1607	acyl-coa hydrolase
JD965_RS07135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JD965_RS07140	COG2076	Multidrug Resistance protein
JD965_RS07145	COG2076	Multidrug Resistance protein
JD965_RS07150	COG0788	formyltetrahydrofolate deformylase activity
JD965_RS07155	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JD965_RS07165	COG1764	response to oxidative stress
JD965_RS07170	COG1846	Transcriptional regulator
JD965_RS07175	COG1764	response to oxidative stress
JD965_RS07190	COG0463	Glycosyl transferase, family 2
JD965_RS07190	COG0457	Tetratricopeptide repeat
JD965_RS07200	COG0590	tRNA wobble adenosine to inosine editing
JD965_RS07205	COG2814	Major facilitator Superfamily
JD965_RS07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JD965_RS07220	COG1404	Belongs to the peptidase S8 family
JD965_RS07225	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS07230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JD965_RS07235	COG1122	ATPase activity
JD965_RS07240	COG4721	ABC-type cobalt transport system, permease component
JD965_RS07245	COG3858	chitin binding
JD965_RS07245	COG1388	LysM domain
JD965_RS07255	COG2239	Acts as a magnesium transporter
JD965_RS07260	COG0789	Transcriptional regulator
JD965_RS07275	COG1846	Transcriptional regulator
JD965_RS07280	COG0726	polysaccharide deacetylase
JD965_RS07285	COG1793	dna ligase
JD965_RS07285	COG3285	dna ligase
JD965_RS07290	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JD965_RS07295	COG5001	Diguanylate cyclase
JD965_RS07295	COG3300	MHYT domain
JD965_RS07300	COG0586	Pfam SNARE associated Golgi protein
JD965_RS07305	COG0861	Integral membrane protein TerC family
JD965_RS07310	COG1191	sigma factor activity
JD965_RS07335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JD965_RS07340	COG2323	membrane
JD965_RS07350	COG3594	Acyltransferase
JD965_RS07355	COG5002	protein histidine kinase activity
JD965_RS07360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JD965_RS07375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JD965_RS07380	COG0436	Aminotransferase
JD965_RS07410	COG3852	Histidine kinase
JD965_RS07415	COG1846	Transcriptional regulator
JD965_RS07420	COG1360	Flagellar Motor Protein
JD965_RS07425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JD965_RS07430	COG0542	response to heat
JD965_RS07435	COG3949	Membrane
JD965_RS07450	COG0720	synthase
JD965_RS07455	COG0602	queuosine metabolic process
JD965_RS07485	COG4873	Protein conserved in bacteria
JD965_RS07495	COG3773	Cell wall hydrolase
JD965_RS07500	COG2244	polysaccharide biosynthetic process
JD965_RS07505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS07510	COG2217	Heavy metal translocating P-type atpase
JD965_RS07515	COG0006	proline dipeptidase activity
JD965_RS07520	COG1609	Transcriptional regulator
JD965_RS07525	COG3711	transcriptional antiterminator
JD965_RS07530	COG2190	(PTS) system
JD965_RS07530	COG1263	PTS System
JD965_RS07530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS07535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JD965_RS07540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JD965_RS07550	COG1533	DNA photolyase activity
JD965_RS07555	COG0840	transmembrane signaling receptor activity
JD965_RS07560	COG2084	Dehydrogenase
JD965_RS07570	COG2340	Cysteine-rich secretory protein family
JD965_RS07575	COG0768	penicillin binding
JD965_RS07585	COG0436	Aminotransferase
JD965_RS07595	COG0784	Response regulator, receiver
JD965_RS07595	COG0835	chemotaxis
JD965_RS07605	COG2814	Major facilitator Superfamily
JD965_RS07610	COG1376	ErfK ybiS ycfS ynhG family protein
JD965_RS07615	COG1408	metallophosphoesterase
JD965_RS07620	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS07630	COG2200	EAL domain
JD965_RS07635	COG4703	Protein of unknown function (DUF1797)
JD965_RS07640	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
JD965_RS07650	COG0517	IMP dehydrogenase activity
JD965_RS07655	COG0583	DNA-binding transcription factor activity
JD965_RS07660	COG0716	FMN binding
JD965_RS07670	COG0716	FMN binding
JD965_RS07695	COG0668	transmembrane transport
JD965_RS07700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS07720	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JD965_RS07725	COG0303	'Molybdopterin
JD965_RS07730	COG1763	Mo-molybdopterin cofactor biosynthetic process
JD965_RS07735	COG0314	molybdopterin synthase activity
JD965_RS07740	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JD965_RS07750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JD965_RS07755	COG1136	(ABC) transporter
JD965_RS07760	COG0577	efflux transmembrane transporter activity
JD965_RS07765	COG1349	DNA-binding transcription factor activity
JD965_RS07770	COG1105	Belongs to the carbohydrate kinase PfkB family
JD965_RS07775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JD965_RS07775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JD965_RS07775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JD965_RS07780	COG0681	Belongs to the peptidase S26 family
JD965_RS07790	COG0488	(ABC) transporter
JD965_RS07795	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JD965_RS07800	COG2309	aminopeptidase activity
JD965_RS07810	COG1077	Cell shape determining protein MreB Mrl
JD965_RS07815	COG2002	toxin-antitoxin pair type II binding
JD965_RS07820	COG3852	Histidine kinase
JD965_RS07825	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
JD965_RS07825	COG2105	PFAM AIG2 family protein
JD965_RS07830	COG0569	domain protein
JD965_RS07840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JD965_RS07850	COG0561	phosphatase activity
JD965_RS07860	COG0242	peptide deformylase activity
JD965_RS07870	COG0497	DNA recombination
JD965_RS07875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JD965_RS07880	COG0022	dehydrogenase e1 component
JD965_RS07885	COG0508	dehydrogenase complex catalyzes the overall conversion of
JD965_RS07890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JD965_RS07895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS07910	COG1982	Orn Lys Arg decarboxylase major
JD965_RS07930	COG0483	inositol monophosphate 1-phosphatase activity
JD965_RS07940	COG3227	Zinc metalloprotease (Elastase)
JD965_RS07955	COG1595	DNA-templated transcription, initiation
JD965_RS07980	COG1217	gtp-binding protein TYPA
JD965_RS07990	COG4896	Protein conserved in bacteria
JD965_RS08000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JD965_RS08005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JD965_RS08010	COG2066	Belongs to the glutaminase family
JD965_RS08020	COG0772	Belongs to the SEDS family
JD965_RS08025	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JD965_RS08040	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JD965_RS08040	COG2010	Cytochrome c
JD965_RS08045	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JD965_RS08050	COG1845	cytochrome c oxidase, subunit III
JD965_RS08055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JD965_RS08060	COG3336	cytochrome c oxidase
JD965_RS08075	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
JD965_RS08080	COG2340	Cysteine-rich secretory protein family
JD965_RS08095	COG3679	Belongs to the UPF0342 family
JD965_RS08105	COG0742	ribosomal rna small subunit methyltransferase
JD965_RS08115	COG3314	Sporulation integral membrane protein YlbJ
JD965_RS08120	COG1752	Esterase of the alpha-beta hydrolase superfamily
JD965_RS08125	COG3480	Lon protease (S16) C-terminal proteolytic domain
JD965_RS08135	COG1399	metal-binding, possibly nucleic acid-binding protein
JD965_RS08155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JD965_RS08175	COG4839	cell division protein FtsL
JD965_RS08180	COG0768	penicillin binding
JD965_RS08185	COG0768	penicillin binding
JD965_RS08205	COG0772	Belongs to the SEDS family
JD965_RS08220	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JD965_RS08225	COG0849	cell division
JD965_RS08230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JD965_RS08235	COG1404	Belongs to the peptidase S8 family
JD965_RS08235	COG4412	M6 family metalloprotease domain protein
JD965_RS08245	COG1191	sigma factor activity
JD965_RS08250	COG1191	sigma factor activity
JD965_RS08255	COG1119	ATPase activity
JD965_RS08260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JD965_RS08265	COG1873	PFAM PRC-barrel domain
JD965_RS08270	COG1496	oxidoreductase activity
JD965_RS08275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JD965_RS08285	COG0762	integral membrane protein
JD965_RS08290	COG2302	S4 RNA-binding domain
JD965_RS08295	COG3599	regulation of cell shape
JD965_RS08300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JD965_RS08305	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JD965_RS08315	COG0564	pseudouridine synthase activity
JD965_RS08325	COG2233	PERMEase
JD965_RS08335	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JD965_RS08340	COG0505	Belongs to the CarA family
JD965_RS08345	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JD965_RS08360	COG0284	orotidine-5'-phosphate decarboxylase activity
JD965_RS08365	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JD965_RS08375	COG0306	phosphate transporter
JD965_RS08390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JD965_RS08395	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
JD965_RS08400	COG1648	precorrin-2 dehydrogenase activity
JD965_RS08410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JD965_RS08415	COG1561	YicC-like family, N-terminal region
JD965_RS08425	COG0194	GDP metabolic process
JD965_RS08435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JD965_RS08440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JD965_RS08445	COG0242	peptide deformylase activity
JD965_RS08455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JD965_RS08455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JD965_RS08465	COG0631	protein serine/threonine phosphatase activity
JD965_RS08470	COG0515	serine threonine protein kinase
JD965_RS08470	COG2815	serine threonine protein kinase
JD965_RS08480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JD965_RS08485	COG1564	THIamine pyrophosphokinase
JD965_RS08500	COG1302	Protein conserved in bacteria
JD965_RS08505	COG1461	Dihydroxyacetone kinase
JD965_RS08510	COG1760	l-serine dehydratase
JD965_RS08520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JD965_RS08535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JD965_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS08555	COG1196	nuclear chromosome segregation
JD965_RS08560	COG0552	protein localization to endoplasmic reticulum
JD965_RS08575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JD965_RS08585	COG1837	Belongs to the UPF0109 family
JD965_RS08610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JD965_RS08625	COG2257	FlhB HrpN YscU SpaS Family
JD965_RS08635	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JD965_RS08640	COG0758	DNA mediated transformation
JD965_RS08645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JD965_RS08655	COG4974	Belongs to the 'phage' integrase family
JD965_RS08675	COG1815	bacterial-type flagellum-dependent cell motility
JD965_RS08680	COG1558	bacterial-type flagellum-dependent cell motility
JD965_RS08685	COG1677	Flagellar hook-basal body complex protein FliE
JD965_RS08690	COG1766	The M ring may be actively involved in energy transduction
JD965_RS08695	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JD965_RS08700	COG1317	bacterial-type flagellum organization
JD965_RS08705	COG1157	protein secretion by the type III secretion system
JD965_RS08710	COG2882	bacterial-type flagellum organization
JD965_RS08715	COG3334	PFAM MgtE intracellular
JD965_RS08720	COG3144	bacterial-type flagellum assembly
JD965_RS08725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JD965_RS08730	COG4786	Flagellar basal body rod
JD965_RS08735	COG1582	Flagellar protein (FlbD)
JD965_RS08740	COG1580	Controls the rotational direction of flagella during chemotaxis
JD965_RS08745	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JD965_RS08750	COG1776	CheC inhibitor of MCP methylation
JD965_RS08750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JD965_RS08755	COG2201	protein-glutamate methylesterase activity
JD965_RS08760	COG3190	flagellar
JD965_RS08765	COG1338	Plays a role in the flagellum-specific transport system
JD965_RS08770	COG1987	bacterial-type flagellum assembly
JD965_RS08775	COG1684	flagellar biosynthetic protein fliR
JD965_RS08780	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JD965_RS08785	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JD965_RS08790	COG1419	protein localization to endoplasmic reticulum
JD965_RS08795	COG0455	bacterial-type flagellum organization
JD965_RS08800	COG2201	protein-glutamate methylesterase activity
JD965_RS08805	COG0643	Histidine kinase
JD965_RS08805	COG2198	Histidine kinase
JD965_RS08810	COG0835	chemotaxis
JD965_RS08815	COG1776	CheC inhibitor of MCP methylation
JD965_RS08825	COG1191	sigma factor activity
JD965_RS08855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JD965_RS08860	COG4589	Belongs to the CDS family
JD965_RS08870	COG0750	zinc metalloprotease
JD965_RS08880	COG2176	DNA-directed DNA polymerase activity
JD965_RS08890	COG0195	Participates in both transcription termination and antitermination
JD965_RS08895	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JD965_RS08900	COG1358	cellular component organization or biogenesis
JD965_RS08910	COG1550	Protein conserved in bacteria
JD965_RS08925	COG0196	riboflavin kinase activity
JD965_RS08940	COG0726	polysaccharide deacetylase
JD965_RS08945	COG0612	Peptidase, M16
JD965_RS08950	COG1873	PFAM PRC-barrel domain
JD965_RS08955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JD965_RS08960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JD965_RS08965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JD965_RS08970	COG0527	aspartate kinase activity
JD965_RS08980	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JD965_RS08985	COG0740	serine-type endopeptidase activity
JD965_RS08995	COG4980	gas vesicle protein
JD965_RS08995	COG1674	ftsk spoiiie
JD965_RS09000	COG2188	Transcriptional regulator
JD965_RS09005	COG2814	Major facilitator Superfamily
JD965_RS09010	COG1846	Transcriptional regulator
JD965_RS09015	COG2409	Drug exporters of the RND superfamily
JD965_RS09015	COG1033	growth of symbiont in host cell
JD965_RS09020	COG0612	Peptidase, M16
JD965_RS09025	COG0612	Peptidase, M16
JD965_RS09030	COG0300	oxidoreductase activity
JD965_RS09045	COG1426	Protein conserved in bacteria
JD965_RS09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JD965_RS09065	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JD965_RS09075	COG1692	metallophosphoesterase
JD965_RS09080	COG2359	stage V sporulation protein S
JD965_RS09105	COG4550	Control of competence regulator ComK, YlbF/YmcA
JD965_RS09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS09160	COG3425	synthase
JD965_RS09165	COG1024	Enoyl-CoA hydratase
JD965_RS09170	COG1024	Enoyl-CoA hydratase
JD965_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS09175	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS09175	COG3321	synthase
JD965_RS09175	COG0300	oxidoreductase activity
JD965_RS09175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS09180	COG0300	oxidoreductase activity
JD965_RS09180	COG4221	oxidoreductase activity
JD965_RS09180	COG3321	synthase
JD965_RS09185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS09185	COG3321	synthase
JD965_RS09185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JD965_RS09185	COG3321	synthase
JD965_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JD965_RS09185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS09185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS09190	COG3321	synthase
JD965_RS09190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09190	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS09190	COG4221	oxidoreductase activity
JD965_RS09195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JD965_RS09195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS09195	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JD965_RS09195	COG3321	synthase
JD965_RS09200	COG2124	cytochrome p450
JD965_RS09205	COG3209	COG3209 Rhs family protein
JD965_RS09210	COG3619	membrane
JD965_RS09220	COG1404	Belongs to the peptidase S8 family
JD965_RS09230	COG4195	phage-related replication protein
JD965_RS09235	COG1764	response to oxidative stress
JD965_RS09245	COG2076	Multidrug Resistance protein
JD965_RS09285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JD965_RS09290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JD965_RS09295	COG4112	unkown
JD965_RS09300	COG0860	N-Acetylmuramoyl-L-alanine amidase
JD965_RS09305	COG0464	growth
JD965_RS09310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JD965_RS09315	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
JD965_RS09320	COG0789	Transcriptional regulator
JD965_RS09325	COG0174	glutamine synthetase
JD965_RS09335	COG2211	Major facilitator Superfamily
JD965_RS09340	COG3507	Belongs to the glycosyl hydrolase 43 family
JD965_RS09355	COG1070	Carbohydrate kinase
JD965_RS09360	COG0574	Belongs to the PEP-utilizing enzyme family
JD965_RS09360	COG3848	Pyruvate phosphate dikinase
JD965_RS09375	COG2378	regulation of single-species biofilm formation
JD965_RS09380	COG2318	DinB family
JD965_RS09385	COG1064	alcohol dehydrogenase
JD965_RS09390	COG4451	ribulose bisphosphate carboxylase, small
JD965_RS09390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JD965_RS09410	COG0456	acetyltransferase
JD965_RS09445	COG3397	chitin binding
JD965_RS09455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JD965_RS09465	COG5434	Belongs to the glycosyl hydrolase 28 family
JD965_RS09475	COG0756	dUTP diphosphatase activity
JD965_RS09480	COG4195	phage-related replication protein
JD965_RS09515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JD965_RS09525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JD965_RS09545	COG0785	Cytochrome C biogenesis protein
JD965_RS09550	COG2201	protein-glutamate methylesterase activity
JD965_RS09565	COG0071	Belongs to the small heat shock protein (HSP20) family
JD965_RS09580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JD965_RS09585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS09605	COG0824	Thioesterase
JD965_RS09615	COG4841	protein insertion into membrane
JD965_RS09625	COG1832	CoA-binding protein
JD965_RS09630	COG0187	DNA topoisomerase II activity
JD965_RS09635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JD965_RS09645	COG1115	amino acid carrier protein
JD965_RS09680	COG3507	Belongs to the glycosyl hydrolase 43 family
JD965_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS09710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JD965_RS09715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JD965_RS09720	COG2610	gluconate transmembrane transporter activity
JD965_RS09725	COG2124	cytochrome p450
JD965_RS09745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JD965_RS09755	COG2246	polysaccharide biosynthetic process
JD965_RS09760	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JD965_RS09765	COG0586	Pfam SNARE associated Golgi protein
JD965_RS09770	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JD965_RS09775	COG1024	Enoyl-CoA hydratase
JD965_RS09780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JD965_RS09785	COG0511	ligase activity, forming carbon-carbon bonds
JD965_RS09790	COG0439	Biotin carboxylase
JD965_RS09795	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS09800	COG1960	acyl-CoA dehydrogenase activity
JD965_RS09805	COG1649	PFAM Uncharacterised BCR, COG1649
JD965_RS09815	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JD965_RS09815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09830	COG2323	membrane
JD965_RS09835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JD965_RS09845	COG2323	membrane
JD965_RS09860	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JD965_RS09905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS09910	COG2027	D-alanyl-D-alanine carboxypeptidase
JD965_RS09915	COG2017	converts alpha-aldose to the beta-anomer
JD965_RS09920	COG0534	Mate efflux family protein
JD965_RS09935	COG0582	viral genome integration into host DNA
JD965_RS09940	COG0166	Belongs to the GPI family
JD965_RS09945	COG0405	Gamma-glutamyltransferase
JD965_RS09950	COG2814	Major facilitator Superfamily
JD965_RS09955	COG0640	Transcriptional regulator
JD965_RS09960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JD965_RS09970	COG0604	alcohol dehydrogenase
JD965_RS09975	COG0493	'glutamate synthase
JD965_RS09980	COG0067	glutamate synthase
JD965_RS09980	COG0070	glutamate synthase
JD965_RS09980	COG0069	glutamate synthase activity
JD965_RS09985	COG0583	DNA-binding transcription factor activity
JD965_RS09990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JD965_RS10005	COG0300	oxidoreductase activity
JD965_RS10010	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JD965_RS10020	COG2814	Major facilitator Superfamily
JD965_RS10025	COG1070	Carbohydrate kinase
JD965_RS10030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JD965_RS10070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JD965_RS10075	COG2207	Transcriptional regulator
JD965_RS10075	COG0662	Cupin 2, conserved barrel domain protein
JD965_RS10080	COG1309	transcriptional regulator
JD965_RS10085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS10095	COG0640	Transcriptional regulator
JD965_RS10100	COG0741	lytic transglycosylase activity
JD965_RS10105	COG2322	membrane
JD965_RS10120	COG1619	proteins homologs of microcin C7 resistance protein MccF
JD965_RS10130	COG3584	3D domain protein
JD965_RS10130	COG1388	LysM domain
JD965_RS10135	COG0514	ATP-dependent DNA helicase (RecQ)
JD965_RS10145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JD965_RS10150	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JD965_RS10165	COG0071	Belongs to the small heat shock protein (HSP20) family
JD965_RS10190	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS10195	COG1657	PFAM Prenyltransferase squalene oxidase
JD965_RS10200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JD965_RS10205	COG0733	neurotransmitter:sodium symporter activity
JD965_RS10210	COG0385	Bile acid
JD965_RS10215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS10220	COG0508	dehydrogenase complex catalyzes the overall conversion of
JD965_RS10230	COG4548	von Willebrand factor, type A
JD965_RS10235	COG0714	Associated with various cellular activities
JD965_RS10240	COG2032	superoxide dismutase activity
JD965_RS10245	COG0791	NLP P60 protein
JD965_RS10245	COG1388	LysM domain
JD965_RS10250	COG1819	glycosyl
JD965_RS10255	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JD965_RS10260	COG0534	Mate efflux family protein
JD965_RS10265	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS10270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JD965_RS10275	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JD965_RS10285	COG2962	Rard protein
JD965_RS10300	COG1942	4-Oxalocrotonate Tautomerase
JD965_RS10310	COG1733	regulation of RNA biosynthetic process
JD965_RS10315	COG0778	Nitroreductase
JD965_RS10320	COG0400	carboxylic ester hydrolase activity
JD965_RS10325	COG0346	lactoylglutathione lyase activity
JD965_RS10335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JD965_RS10345	COG2723	6-phospho-beta-galactosidase activity
JD965_RS10350	COG2188	Transcriptional regulator
JD965_RS10355	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS10355	COG0793	Belongs to the peptidase S41A family
JD965_RS10360	COG2226	methyltransferase
JD965_RS10370	COG1876	peptidase activity
JD965_RS10390	COG0671	phosphoesterase, PA-phosphatase related
JD965_RS10420	COG1509	lysine 2,3-aminomutase activity
JD965_RS10425	COG0456	acetyltransferase
JD965_RS10430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JD965_RS10435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JD965_RS10440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JD965_RS10445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JD965_RS10450	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
JD965_RS10460	COG0456	acetyltransferase
JD965_RS10465	COG0463	Glycosyl transferase, family 2
JD965_RS10480	COG4641	Protein conserved in bacteria
JD965_RS10490	COG1086	Polysaccharide biosynthesis protein
JD965_RS10520	COG1357	PFAM Pentapeptide repeats (8 copies)
JD965_RS10535	COG0477	Major facilitator Superfamily
JD965_RS10570	COG0457	Tetratricopeptide repeat
JD965_RS10580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JD965_RS10585	COG0583	DNA-binding transcription factor activity
JD965_RS10610	COG0457	Tetratricopeptide repeat
JD965_RS10615	COG4282	regulation of fungal-type cell wall biogenesis
JD965_RS10620	COG1525	nuclease
JD965_RS10635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JD965_RS10655	COG1846	Transcriptional regulator
JD965_RS10660	COG4698	Protein conserved in bacteria
JD965_RS10665	COG2755	lipolytic protein G-D-S-L family
JD965_RS10670	COG1999	signal sequence binding
JD965_RS10680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JD965_RS10685	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JD965_RS10690	COG1272	protein, Hemolysin III
JD965_RS10695	COG0204	Acyl-transferase
JD965_RS10700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JD965_RS10715	COG2521	methyltransferase
JD965_RS10715	COG2136	Putative SAM-dependent methyltransferase
JD965_RS10730	COG1413	lyase activity
JD965_RS10740	COG0386	Belongs to the glutathione peroxidase family
JD965_RS10750	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JD965_RS10765	COG1278	Cold shock
JD965_RS10785	COG0328	RNA-DNA hybrid ribonuclease activity
JD965_RS10790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JD965_RS10795	COG0328	RNA-DNA hybrid ribonuclease activity
JD965_RS10805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JD965_RS10820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JD965_RS10830	COG1755	Isoprenylcysteine carboxyl methyltransferase
JD965_RS10835	COG3424	synthase
JD965_RS10860	COG1335	isochorismatase
JD965_RS10870	COG2233	PERMEase
JD965_RS10880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JD965_RS10885	COG1199	ATP-dependent helicase activity
JD965_RS10900	COG0116	Belongs to the methyltransferase superfamily
JD965_RS10930	COG3359	exonuclease
JD965_RS10935	COG1111	helicase
JD965_RS10935	COG1205	dead DEAH box helicase
JD965_RS10940	COG2190	(PTS) system
JD965_RS10945	COG0071	Belongs to the small heat shock protein (HSP20) family
JD965_RS10985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JD965_RS10985	COG4499	WXG100 protein secretion system (Wss), protein YukC
JD965_RS10995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JD965_RS11000	COG3935	DnaD domain protein
JD965_RS11010	COG0436	Aminotransferase
JD965_RS11015	COG5353	protein conserved in bacteria
JD965_RS11025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JD965_RS11025	COG1199	ATP-dependent helicase activity
JD965_RS11045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JD965_RS11045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JD965_RS11055	COG0438	transferase activity, transferring glycosyl groups
JD965_RS11060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JD965_RS11075	COG1694	Mazg nucleotide pyrophosphohydrolase
JD965_RS11080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS11085	COG2140	Oxalate decarboxylase
JD965_RS11095	COG4347	Protein of unknown function (DUF1405)
JD965_RS11100	COG2010	Cytochrome c
JD965_RS11100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JD965_RS11105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JD965_RS11110	COG0723	plastoquinol--plastocyanin reductase activity
JD965_RS11125	COG0457	Tetratricopeptide repeat
JD965_RS11135	COG0287	Prephenate dehydrogenase
JD965_RS11170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JD965_RS11175	COG4401	Chorismate mutase type I
JD965_RS11190	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JD965_RS11195	COG0105	UTP biosynthetic process
JD965_RS11200	COG0142	geranyltranstransferase activity
JD965_RS11210	COG0142	geranyltranstransferase activity
JD965_RS11225	COG0776	regulation of translation
JD965_RS11230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JD965_RS11270	COG0539	negative regulation of cytoplasmic translation
JD965_RS11285	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
JD965_RS11290	COG2959	enzyme of heme biosynthesis
JD965_RS11295	COG3773	Cell wall hydrolase
JD965_RS11295	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS11300	COG2339	peptidase activity
JD965_RS11305	COG0492	ferredoxin-NADP+ reductase activity
JD965_RS11310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JD965_RS11315	COG4862	establishment of competence for transformation
JD965_RS11320	COG1408	metallophosphoesterase
JD965_RS11330	COG1388	LysM domain
JD965_RS11335	COG1266	CAAX protease self-immunity
JD965_RS11340	COG0514	ATP-dependent DNA helicase (RecQ)
JD965_RS11345	COG4955	Helix-turn-helix domain
JD965_RS11350	COG1141	Ferredoxin
JD965_RS11355	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JD965_RS11360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JD965_RS11370	COG1595	DNA-templated transcription, initiation
JD965_RS11375	COG5002	protein histidine kinase activity
JD965_RS11380	COG0745	RESPONSE REGULATOR receiver
JD965_RS11385	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JD965_RS11390	COG1333	cytochrome c biogenesis protein
JD965_RS11395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS11400	COG1187	pseudouridine synthase activity
JD965_RS11405	COG0700	Nucleoside recognition
JD965_RS11410	COG2715	membrane protein required for spore maturation
JD965_RS11415	COG1686	Belongs to the peptidase S11 family
JD965_RS11440	COG1547	Domain of unknown function (DUF309)
JD965_RS11445	COG0456	acetyltransferase
JD965_RS11460	COG0307	riboflavin synthase, alpha
JD965_RS11465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JD965_RS11465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JD965_RS11475	COG0681	Belongs to the peptidase S26 family
JD965_RS11485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JD965_RS11490	COG4086	secreted protein
JD965_RS11495	COG0019	diaminopimelate decarboxylase activity
JD965_RS11500	COG0697	spore germination
JD965_RS11515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JD965_RS11535	COG1191	sigma factor activity
JD965_RS11545	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS11550	COG1686	Belongs to the peptidase S11 family
JD965_RS11555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JD965_RS11560	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JD965_RS11565	COG4974	Belongs to the 'phage' integrase family
JD965_RS11575	COG0735	belongs to the Fur family
JD965_RS11580	COG1300	Membrane
JD965_RS11590	COG0281	malic enzyme
JD965_RS11595	COG1757	Na H antiporter
JD965_RS11600	COG1027	Aspartate ammonia-lyase
JD965_RS11605	COG0252	asparaginase activity
JD965_RS11610	COG1396	sequence-specific DNA binding
JD965_RS11615	COG1379	DNA repair
JD965_RS11620	COG0494	nUDIX hydrolase
JD965_RS11630	COG0667	Aldo Keto reductase
JD965_RS11640	COG1073	alpha beta
JD965_RS11650	COG4918	Iron-sulphur cluster biosynthesis
JD965_RS11655	COG0456	acetyltransferase
JD965_RS11655	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JD965_RS11660	COG2329	Antibiotic biosynthesis monooxygenase
JD965_RS11665	COG0456	acetyltransferase
JD965_RS11670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JD965_RS11685	COG0628	permease
JD965_RS11695	COG0346	lactoylglutathione lyase activity
JD965_RS11705	COG3048	D-serine ammonia-lyase activity
JD965_RS11710	COG0300	oxidoreductase activity
JD965_RS11715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS11720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JD965_RS11730	COG0596	Alpha beta hydrolase
JD965_RS11745	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JD965_RS11750	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JD965_RS11765	COG0706	membrane insertase activity
JD965_RS11790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JD965_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS11800	COG2986	histidine ammonia-lyase
JD965_RS11805	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS11810	COG0109	protoheme IX farnesyltransferase activity
JD965_RS11815	COG2195	Cleaves the N-terminal amino acid of tripeptides
JD965_RS11820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JD965_RS11825	COG0346	lactoylglutathione lyase activity
JD965_RS11835	COG1376	ErfK ybiS ycfS ynhG family protein
JD965_RS11840	COG4129	membrane
JD965_RS11845	COG1126	abc transporter atp-binding protein
JD965_RS11850	COG0765	amino acid transport
JD965_RS11855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JD965_RS11865	COG1597	lipid kinase activity
JD965_RS11870	COG0508	dehydrogenase complex catalyzes the overall conversion of
JD965_RS11875	COG0022	dehydrogenase e1 component
JD965_RS11880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JD965_RS11885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JD965_RS11890	COG3426	butyrate kinase activity
JD965_RS11895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JD965_RS11900	COG0280	phosphate acetyltransferase
JD965_RS11905	COG3829	transcription factor binding
JD965_RS11905	COG3290	protein histidine kinase activity
JD965_RS11915	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JD965_RS11920	COG2079	MmgE PrpD family protein
JD965_RS11925	COG0372	Belongs to the citrate synthase family
JD965_RS11930	COG1960	acyl-CoA dehydrogenase activity
JD965_RS11935	COG1250	3-hydroxyacyl-CoA dehydrogenase
JD965_RS11940	COG0183	Belongs to the thiolase family
JD965_RS11945	COG0584	glycerophosphoryl diester phosphodiesterase
JD965_RS11950	COG0860	N-Acetylmuramoyl-L-alanine amidase
JD965_RS11975	COG1902	pentaerythritol trinitrate reductase activity
JD965_RS11990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JD965_RS11995	COG0745	RESPONSE REGULATOR receiver
JD965_RS12000	COG0750	zinc metalloprotease
JD965_RS12005	COG0497	DNA recombination
JD965_RS12015	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JD965_RS12025	COG0142	geranyltranstransferase activity
JD965_RS12035	COG1570	exodeoxyribonuclease VII activity
JD965_RS12050	COG1302	Protein conserved in bacteria
JD965_RS12055	COG0439	Biotin carboxylase
JD965_RS12060	COG0511	ligase activity, forming carbon-carbon bonds
JD965_RS12100	COG3854	ATPases associated with a variety of cellular activities
JD965_RS12115	COG0006	proline dipeptidase activity
JD965_RS12125	COG3872	metal-dependent enzyme
JD965_RS12135	COG1752	Esterase of the alpha-beta hydrolase superfamily
JD965_RS12150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JD965_RS12170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JD965_RS12185	COG1396	sequence-specific DNA binding
JD965_RS12195	COG0681	Belongs to the peptidase S26 family
JD965_RS12220	COG4940	Competence protein ComGF
JD965_RS12230	COG4970	Tfp pilus assembly protein FimT
JD965_RS12235	COG4537	Required for transformation and DNA binding
JD965_RS12240	COG1459	type II secretion system
JD965_RS12245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JD965_RS12250	COG0598	Magnesium transport protein CorA
JD965_RS12255	COG1253	flavin adenine dinucleotide binding
JD965_RS12260	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS12270	COG1393	Belongs to the ArsC family
JD965_RS12280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS12290	COG0011	TIGRFAM Protein of
JD965_RS12300	COG2866	Carboxypeptidase
JD965_RS12305	COG1940	carbohydrate kinase activity
JD965_RS12310	COG4483	Protein conserved in bacteria
JD965_RS12315	COG1757	Na H antiporter
JD965_RS12330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JD965_RS12345	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JD965_RS12350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JD965_RS12355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JD965_RS12360	COG0581	inorganic phosphate transmembrane transporter activity
JD965_RS12365	COG0573	inorganic phosphate transmembrane transporter activity
JD965_RS12370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JD965_RS12375	COG0768	penicillin binding
JD965_RS12380	COG0477	Major facilitator Superfamily
JD965_RS12385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JD965_RS12390	COG2839	Protein conserved in bacteria
JD965_RS12395	COG5521	maltodextrose utilization protein MalA
JD965_RS12400	COG1388	LysM domain
JD965_RS12410	COG4709	membrane
JD965_RS12415	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
JD965_RS12425	COG0735	belongs to the Fur family
JD965_RS12430	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS12445	COG0513	Belongs to the DEAD box helicase family
JD965_RS12460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JD965_RS12465	COG2384	SAM-dependent methyltransferase
JD965_RS12470	COG2010	Cytochrome c
JD965_RS12475	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JD965_RS12480	COG0358	DNA primase activity
JD965_RS12495	COG0517	IMP dehydrogenase activity
JD965_RS12500	COG0751	glycine-tRNA ligase activity
JD965_RS12520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JD965_RS12525	COG0295	cytidine deaminase activity
JD965_RS12530	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JD965_RS12540	COG1480	7TM receptor with intracellular HD hydrolase
JD965_RS12545	COG1702	phosphate starvation-inducible protein PhoH
JD965_RS12550	COG0561	phosphatase activity
JD965_RS12565	COG4864	UPF0365 protein
JD965_RS12570	COG1030	water channel activity
JD965_RS12575	COG1610	YqeY-like protein
JD965_RS12585	COG1283	sodium-dependent phosphate transmembrane transporter activity
JD965_RS12590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JD965_RS12595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JD965_RS12625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JD965_RS12640	COG0860	N-Acetylmuramoyl-L-alanine amidase
JD965_RS12655	COG1466	dna polymerase III delta subunit
JD965_RS12670	COG0658	competence protein
JD965_RS12670	COG2333	competence protein COMEC
JD965_RS12675	COG2131	deaminase
JD965_RS12680	COG1555	photosystem II stabilization
JD965_RS12680	COG1596	polysaccharide export
JD965_RS12685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JD965_RS12690	COG2226	methyltransferase
JD965_RS12695	COG0799	negative regulation of ribosome biogenesis
JD965_RS12700	COG1713	HD superfamily hydrolase involved in NAD metabolism
JD965_RS12710	COG1534	Rna-binding protein
JD965_RS12715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JD965_RS12720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JD965_RS12725	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JD965_RS12735	COG2755	lipolytic protein G-D-S-L family
JD965_RS12745	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS12745	COG5632	N-Acetylmuramoyl-L-alanine amidase
JD965_RS12750	COG0398	Pfam SNARE associated Golgi protein
JD965_RS12770	COG1733	regulation of RNA biosynthetic process
JD965_RS12775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JD965_RS12790	COG0583	DNA-binding transcription factor activity
JD965_RS12800	COG0656	L-ascorbic acid biosynthetic process
JD965_RS12830	COG0563	adenylate kinase activity
JD965_RS12840	COG2814	Major facilitator Superfamily
JD965_RS12855	COG2318	DinB family
JD965_RS12865	COG0561	phosphatase activity
JD965_RS12870	COG0561	phosphatase activity
JD965_RS12885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JD965_RS12890	COG2814	Major facilitator Superfamily
JD965_RS12895	COG2124	cytochrome p450
JD965_RS12895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JD965_RS12900	COG1309	transcriptional regulator
JD965_RS12905	COG2226	methyltransferase
JD965_RS12920	COG2116	formate transmembrane transporter activity
JD965_RS12925	COG5609	conserved protein (DUF2294)
JD965_RS12930	COG3383	formate dehydrogenase (NAD+) activity
JD965_RS12935	COG2427	Protein of unknown function (DUF1641)
JD965_RS12945	COG0626	cystathionine gamma-synthase activity
JD965_RS12950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JD965_RS12975	COG0768	penicillin binding
JD965_RS12990	COG0826	peptidase U32
JD965_RS12995	COG0826	peptidase U32
JD965_RS13000	COG4122	O-methyltransferase activity
JD965_RS13005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JD965_RS13020	COG4472	Bacterial protein of unknown function (DUF965)
JD965_RS13030	COG0628	permease
JD965_RS13035	COG1126	abc transporter atp-binding protein
JD965_RS13040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JD965_RS13045	COG0765	amino acid transport
JD965_RS13050	COG0765	amino acid transport
JD965_RS13070	COG3881	PFAM PRC-barrel domain
JD965_RS13075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JD965_RS13080	COG0457	Tetratricopeptide repeat
JD965_RS13090	COG1104	cysteine desulfurase activity
JD965_RS13095	COG1959	2 iron, 2 sulfur cluster binding
JD965_RS13100	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JD965_RS13105	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JD965_RS13130	COG3103	Sh3 type 3 domain protein
JD965_RS13130	COG4991	sh3 domain protein
JD965_RS13130	COG0860	N-Acetylmuramoyl-L-alanine amidase
JD965_RS13135	COG1490	D-aminoacyl-tRNA deacylase activity
JD965_RS13140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JD965_RS13150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JD965_RS13150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JD965_RS13155	COG5416	Lipopolysaccharide assembly protein A domain
JD965_RS13160	COG0490	domain, Protein
JD965_RS13165	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JD965_RS13165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JD965_RS13175	COG2244	polysaccharide biosynthetic process
JD965_RS13180	COG2323	membrane
JD965_RS13195	COG1862	Preprotein translocase
JD965_RS13235	COG1388	LysM domain
JD965_RS13245	COG0157	Belongs to the NadC ModD family
JD965_RS13250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JD965_RS13255	COG1104	cysteine desulfurase activity
JD965_RS13260	COG1827	regulation of RNA biosynthetic process
JD965_RS13265	COG0077	Prephenate dehydratase
JD965_RS13280	COG3290	protein histidine kinase activity
JD965_RS13285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JD965_RS13290	COG2868	ribosomal protein
JD965_RS13300	COG1994	Peptidase M50
JD965_RS13305	COG0739	heme binding
JD965_RS13310	COG2894	cell division
JD965_RS13320	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JD965_RS13330	COG1077	Cell shape determining protein MreB Mrl
JD965_RS13345	COG0457	Tetratricopeptide repeat
JD965_RS13450	COG0740	serine-type endopeptidase activity
JD965_RS13570	COG1396	sequence-specific DNA binding
JD965_RS13600	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JD965_RS13605	COG0285	dihydrofolate synthase activity
JD965_RS13610	COG0525	valine-tRNA ligase activity
JD965_RS13620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JD965_RS13625	COG1388	LysM domain
JD965_RS13635	COG0113	porphobilinogen synthase activity
JD965_RS13640	COG1587	Uroporphyrinogen-III synthase
JD965_RS13650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JD965_RS13670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JD965_RS13675	COG1067	ATP-dependent peptidase activity
JD965_RS13675	COG0470	DNA polymerase III
JD965_RS13690	COG0457	Tetratricopeptide repeat
JD965_RS13690	COG1477	protein flavinylation
JD965_RS13705	COG0473	3-isopropylmalate dehydrogenase activity
JD965_RS13720	COG0440	acetolactate synthase activity
JD965_RS13725	COG0028	Belongs to the TPP enzyme family
JD965_RS13755	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
JD965_RS13770	COG0622	Phosphoesterase
JD965_RS13775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JD965_RS13785	COG5401	PFAM Sporulation and spore germination
JD965_RS13795	COG1846	Transcriptional regulator
JD965_RS13800	COG2197	response regulator
JD965_RS13805	COG0824	Thioesterase
JD965_RS13810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JD965_RS13815	COG1053	succinate dehydrogenase
JD965_RS13820	COG2009	succinate dehydrogenase
JD965_RS13825	COG1719	4-vinyl reductase, 4VR
JD965_RS13830	COG0527	aspartate kinase activity
JD965_RS13840	COG3118	belongs to the thioredoxin family
JD965_RS13845	COG3534	alpha-L-arabinofuranosidase
JD965_RS13850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JD965_RS13855	COG2086	electron transfer activity
JD965_RS13860	COG1024	Enoyl-CoA hydratase
JD965_RS13865	COG1309	transcriptional regulator
JD965_RS13870	COG0318	PFAM AMP-dependent synthetase and ligase
JD965_RS13880	COG3766	membrane
JD965_RS13890	COG1796	DNA polymerase
JD965_RS13890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JD965_RS13895	COG1286	toxin biosynthetic process
JD965_RS13910	COG0072	phenylalanine-tRNA ligase activity
JD965_RS13910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JD965_RS13915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JD965_RS13920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JD965_RS13930	COG3835	regulator
JD965_RS13935	COG0277	FAD linked oxidase domain protein
JD965_RS13940	COG0247	lactate metabolic process
JD965_RS13945	COG1966	Carbon starvation protein
JD965_RS13950	COG3534	alpha-L-arabinofuranosidase
JD965_RS13955	COG0395	ABC-type sugar transport system, permease component
JD965_RS13965	COG1653	transport
JD965_RS13975	COG0647	UMP catabolic process
JD965_RS13980	COG0235	Class ii aldolase
JD965_RS13985	COG1069	ribulokinase activity
JD965_RS13990	COG2160	L-arabinose isomerase activity
JD965_RS13995	COG3507	Belongs to the glycosyl hydrolase 43 family
JD965_RS14000	COG1363	Peptidase, m42
JD965_RS14010	COG3326	Membrane
JD965_RS14025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JD965_RS14030	COG1346	cytolysis
JD965_RS14035	COG1380	Effector of murein hydrolase LrgA
JD965_RS14040	COG3279	Response regulator of the LytR AlgR family
JD965_RS14045	COG3275	phosphorelay sensor kinase activity
JD965_RS14050	COG1011	Hydrolase
JD965_RS14065	COG0398	Pfam SNARE associated Golgi protein
JD965_RS14070	COG1484	DNA-dependent DNA replication
JD965_RS14075	COG3611	Membrane attachment protein
JD965_RS14090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JD965_RS14095	COG1733	regulation of RNA biosynthetic process
JD965_RS14100	COG2814	Major facilitator Superfamily
JD965_RS14105	COG0656	L-ascorbic acid biosynthetic process
JD965_RS14110	COG0237	dephospho-CoA kinase activity
JD965_RS14115	COG1971	Probably functions as a manganese efflux pump
JD965_RS14120	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JD965_RS14125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JD965_RS14125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JD965_RS14130	COG5002	protein histidine kinase activity
JD965_RS14135	COG0745	RESPONSE REGULATOR receiver
JD965_RS14145	COG0538	isocitrate dehydrogenase activity
JD965_RS14150	COG0372	Belongs to the citrate synthase family
JD965_RS14185	COG0628	permease
JD965_RS14190	COG3030	protein affecting phage T7 exclusion by the F plasmid
JD965_RS14195	COG0469	pyruvate kinase activity
JD965_RS14215	COG0281	malic enzyme
JD965_RS14220	COG0587	DNA-directed DNA polymerase activity
JD965_RS14240	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JD965_RS14250	COG4109	DRTGG domain
JD965_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS14275	COG0521	Mo-molybdopterin cofactor biosynthetic process
JD965_RS14290	COG0827	DNA restriction-modification system
JD965_RS14295	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JD965_RS14300	COG3874	Sporulation protein YtfJ
JD965_RS14310	COG1714	RDD family
JD965_RS14315	COG0616	signal peptide processing
JD965_RS14320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JD965_RS14325	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JD965_RS14330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JD965_RS14345	COG1104	cysteine desulfurase activity
JD965_RS14350	COG1114	Component of the transport system for branched-chain amino acids
JD965_RS14360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JD965_RS14365	COG1309	transcriptional regulator
JD965_RS14370	COG1956	GAF domain-containing protein
JD965_RS14375	COG2199	diguanylate cyclase activity
JD965_RS14375	COG2203	Gaf domain
JD965_RS14390	COG4282	regulation of fungal-type cell wall biogenesis
JD965_RS14420	COG0693	protein deglycase activity
JD965_RS14435	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JD965_RS14440	COG1378	Sugar-specific transcriptional regulator TrmB
JD965_RS14460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JD965_RS14465	COG0454	-acetyltransferase
JD965_RS14470	COG0517	IMP dehydrogenase activity
JD965_RS14475	COG0123	including yeast histone deacetylase and acetoin utilization protein
JD965_RS14480	COG1360	Flagellar Motor Protein
JD965_RS14485	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JD965_RS14490	COG1609	Transcriptional regulator
JD965_RS14495	COG1605	Chorismate mutase
JD965_RS14495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JD965_RS14500	COG3118	belongs to the thioredoxin family
JD965_RS14505	COG4980	gas vesicle protein
JD965_RS14510	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JD965_RS14520	COG1674	ftsk spoiiie
JD965_RS14525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JD965_RS14535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS14545	COG1363	Peptidase, m42
JD965_RS14550	COG5584	Small secreted protein
JD965_RS14555	COG0281	malic enzyme
JD965_RS14560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JD965_RS14575	COG0510	thiamine kinase activity
JD965_RS14580	COG1597	lipid kinase activity
JD965_RS14590	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JD965_RS14595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JD965_RS14600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JD965_RS14605	COG2252	PERMEase
JD965_RS14610	COG4473	ABC transporter
JD965_RS14615	COG1131	(ABC) transporter
JD965_RS14620	COG1349	DNA-binding transcription factor activity
JD965_RS14625	COG1187	pseudouridine synthase activity
JD965_RS14630	COG2244	polysaccharide biosynthetic process
JD965_RS14635	COG2081	HI0933 family
JD965_RS14640	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JD965_RS14650	COG1609	Transcriptional regulator
JD965_RS14655	COG1653	transport
JD965_RS14660	COG1175	transmembrane transport
JD965_RS14665	COG0395	ABC-type sugar transport system, permease component
JD965_RS14670	COG1486	melibiose metabolic process
JD965_RS14680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JD965_RS14695	COG1366	Belongs to the anti-sigma-factor antagonist family
JD965_RS14695	COG2202	Pas domain
JD965_RS14700	COG2814	Major facilitator Superfamily
JD965_RS14705	COG5522	Integral membrane protein (intg_mem_TP0381)
JD965_RS14710	COG0577	efflux transmembrane transporter activity
JD965_RS14715	COG1136	(ABC) transporter
JD965_RS14720	COG2205	protein histidine kinase activity
JD965_RS14725	COG0745	RESPONSE REGULATOR receiver
JD965_RS14730	COG0577	efflux transmembrane transporter activity
JD965_RS14735	COG1136	(ABC) transporter
JD965_RS14755	COG1131	(ABC) transporter
JD965_RS14760	COG1725	Transcriptional regulator
JD965_RS14770	COG0640	Transcriptional regulator
JD965_RS14775	COG0477	Major facilitator Superfamily
JD965_RS14780	COG1242	4 iron, 4 sulfur cluster binding
JD965_RS14785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JD965_RS14800	COG2267	carboxylic ester hydrolase activity
JD965_RS14805	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JD965_RS14810	COG1113	amino acid transport
JD965_RS14815	COG0367	asparagine synthase
JD965_RS14835	COG1506	peptidase
JD965_RS14840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JD965_RS14845	COG1116	anion transmembrane transporter activity
JD965_RS14850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JD965_RS14855	COG0494	nUDIX hydrolase
JD965_RS14860	COG4824	toxin secretion phage lysis holin
JD965_RS14865	COG0783	Belongs to the Dps family
JD965_RS14890	COG0288	reversible hydration of carbon dioxide
JD965_RS14900	COG1271	oxidase subunit
JD965_RS14905	COG1294	oxidase, subunit
JD965_RS14915	COG4948	Mandelate Racemase Muconate Lactonizing
JD965_RS14925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JD965_RS14930	COG0596	Alpha beta hydrolase
JD965_RS14940	COG1169	isochorismate synthase
JD965_RS14945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JD965_RS14950	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
JD965_RS15075	COG3859	Proton-coupled thiamine transporter YuaJ
JD965_RS15080	COG2268	Band 7 protein
JD965_RS15085	COG1585	Membrane protein implicated in regulation of membrane protease activity
JD965_RS15090	COG2318	DinB family
JD965_RS15100	COG1454	alcohol dehydrogenase
JD965_RS15105	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS15110	COG1510	regulation of RNA biosynthetic process
JD965_RS15120	COG0569	domain protein
JD965_RS15125	COG1705	Flagellar rod assembly protein muramidase FlgJ
JD965_RS15130	COG1017	nitric oxide dioxygenase activity
JD965_RS15130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JD965_RS15170	COG0628	permease
JD965_RS15175	COG0673	inositol 2-dehydrogenase activity
JD965_RS15180	COG0693	protein deglycase activity
JD965_RS15185	COG0840	transmembrane signaling receptor activity
JD965_RS15190	COG0840	transmembrane signaling receptor activity
JD965_RS15195	COG0840	transmembrane signaling receptor activity
JD965_RS15200	COG0840	transmembrane signaling receptor activity
JD965_RS15215	COG2070	2-Nitropropane dioxygenase
JD965_RS15220	COG0432	Pfam Uncharacterised protein family UPF0047
JD965_RS15225	COG0366	Alpha amylase catalytic
JD965_RS15230	COG1253	flavin adenine dinucleotide binding
JD965_RS15235	COG2738	Putative neutral zinc metallopeptidase
JD965_RS15250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JD965_RS15275	COG1335	isochorismatase
JD965_RS15280	COG1979	alcohol dehydrogenase
JD965_RS15285	COG1979	alcohol dehydrogenase
JD965_RS15290	COG2155	Conserved Protein
JD965_RS15295	COG1098	S1 RNA binding domain
JD965_RS15300	COG0436	Aminotransferase
JD965_RS15305	COG1522	sequence-specific DNA binding
JD965_RS15310	COG2267	carboxylic ester hydrolase activity
JD965_RS15320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JD965_RS15325	COG2205	protein histidine kinase activity
JD965_RS15335	COG5018	Exonuclease
JD965_RS15340	COG2814	Major facilitator Superfamily
JD965_RS15345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JD965_RS15350	COG3011	Protein conserved in bacteria
JD965_RS15360	COG3290	protein histidine kinase activity
JD965_RS15365	COG4565	transcriptional regulatory protein
JD965_RS15370	COG1744	ABC transporter substrate-binding protein PnrA-like
JD965_RS15375	COG3845	ABC transporter
JD965_RS15380	COG4603	Belongs to the binding-protein-dependent transport system permease family
JD965_RS15385	COG1079	Belongs to the binding-protein-dependent transport system permease family
JD965_RS15395	COG2111	Na H antiporter
JD965_RS15395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JD965_RS15400	COG2111	Na H antiporter
JD965_RS15405	COG1006	Multisubunit Na H antiporter MnhC subunit
JD965_RS15410	COG0651	ATP synthesis coupled electron transport
JD965_RS15415	COG1863	multisubunit Na H antiporter MnhE subunit
JD965_RS15420	COG2212	antiporter activity
JD965_RS15425	COG1320	monovalent cation:proton antiporter activity
JD965_RS15430	COG2050	protein possibly involved in aromatic compounds catabolism
JD965_RS15435	COG2197	response regulator
JD965_RS15440	COG4585	Histidine kinase
JD965_RS15450	COG0142	geranyltranstransferase activity
JD965_RS15465	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JD965_RS15470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JD965_RS15475	COG1335	isochorismatase
JD965_RS15495	COG0628	permease
JD965_RS15505	COG1418	mRNA catabolic process
JD965_RS15510	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS15520	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JD965_RS15520	COG2508	Transcriptional regulator
JD965_RS15525	COG0686	Belongs to the AlaDH PNT family
JD965_RS15530	COG5634	Uncharacterized conserved protein (DUF2278)
JD965_RS15535	COG3251	PFAM MbtH domain protein
JD965_RS15540	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JD965_RS15545	COG3433	isochorismatase activity
JD965_RS15545	COG1535	isochorismatase
JD965_RS15550	COG1021	2,3-dihydroxybenzoate-AMP ligase
JD965_RS15555	COG1169	isochorismate synthase
JD965_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS15565	COG2819	hydrolase of the alpha beta superfamily
JD965_RS15570	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JD965_RS15575	COG1268	BioY protein
JD965_RS15580	COG2056	Na+-H+ antiporter family
JD965_RS15590	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JD965_RS15595	COG3584	3D domain protein
JD965_RS15610	COG1252	NADH dehydrogenase
JD965_RS15645	COG1131	(ABC) transporter
JD965_RS15670	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
JD965_RS15675	COG0316	Belongs to the HesB IscA family
JD965_RS15685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JD965_RS15695	COG1252	NADH dehydrogenase
JD965_RS15700	COG4837	Protein of unknown function (DUF1462)
JD965_RS15705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JD965_RS15710	COG1506	peptidase
JD965_RS15710	COG4946	Tricorn protease homolog
JD965_RS15710	COG0823	Involved in the tonB-independent uptake of proteins
JD965_RS15720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JD965_RS15725	COG0460	homoserine dehydrogenase
JD965_RS15730	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JD965_RS15735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JD965_RS15740	COG0647	UMP catabolic process
JD965_RS15745	COG2445	Protein of unknown function DUF86
JD965_RS15750	COG4470	Protein conserved in bacteria
JD965_RS15760	COG0739	heme binding
JD965_RS15770	COG0737	Belongs to the 5'-nucleotidase family
JD965_RS15775	COG0730	response to heat
JD965_RS15780	COG1801	Protein of unknown function DUF72
JD965_RS15790	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JD965_RS15795	COG2508	Transcriptional regulator
JD965_RS15800	COG2233	PERMEase
JD965_RS15805	COG2233	PERMEase
JD965_RS15810	COG3648	Uricase
JD965_RS15810	COG3195	allantoin biosynthetic process
JD965_RS15815	COG2351	hydroxyisourate hydrolase activity
JD965_RS15820	COG1794	racemase activity, acting on amino acids and derivatives
JD965_RS15825	COG2080	2 iron, 2 sulfur cluster binding
JD965_RS15830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JD965_RS15835	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
JD965_RS15840	COG2068	MobA-Related Protein
JD965_RS15845	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JD965_RS15850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JD965_RS15855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JD965_RS15860	COG2356	endonuclease I
JD965_RS15865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JD965_RS15870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JD965_RS15875	COG1116	anion transmembrane transporter activity
JD965_RS15885	COG3842	ATPase activity
JD965_RS15890	COG2188	Transcriptional regulator
JD965_RS15895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JD965_RS15900	COG0395	ABC-type sugar transport system, permease component
JD965_RS15905	COG1175	transmembrane transport
JD965_RS15910	COG1653	transport
JD965_RS15915	COG2222	sugar isomerase
JD965_RS15920	COG0789	Transcriptional regulator
JD965_RS15930	COG0322	excinuclease ABC activity
JD965_RS15935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JD965_RS15955	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS15960	COG0719	Fe-S assembly protein
JD965_RS15965	COG0822	iron-sulfur transferase activity
JD965_RS15970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JD965_RS15975	COG0719	Fe-S assembly protein
JD965_RS15980	COG0396	ATPase activity
JD965_RS15990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JD965_RS15995	COG1464	Belongs to the NlpA lipoprotein family
JD965_RS16000	COG2011	ABC-type metal ion transport system permease component
JD965_RS16005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JD965_RS16015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JD965_RS16020	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JD965_RS16035	COG1393	Belongs to the ArsC family
JD965_RS16040	COG1960	acyl-CoA dehydrogenase activity
JD965_RS16045	COG0183	Belongs to the thiolase family
JD965_RS16050	COG1250	3-hydroxyacyl-CoA dehydrogenase
JD965_RS16050	COG1024	Enoyl-CoA hydratase
JD965_RS16070	COG5577	PFAM Coat F domain
JD965_RS16075	COG1846	Transcriptional regulator
JD965_RS16080	COG0477	Major facilitator Superfamily
JD965_RS16085	COG1942	4-Oxalocrotonate Tautomerase
JD965_RS16095	COG0583	DNA-binding transcription factor activity
JD965_RS16105	COG1120	ATPase activity
JD965_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS16125	COG0783	Belongs to the Dps family
JD965_RS16130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JD965_RS16135	COG0745	RESPONSE REGULATOR receiver
JD965_RS16140	COG2205	protein histidine kinase activity
JD965_RS16140	COG2770	Histidine kinase
JD965_RS16150	COG1309	transcriptional regulator
JD965_RS16155	COG0114	fumarate hydratase activity
JD965_RS16165	COG0697	spore germination
JD965_RS16170	COG0814	amino acid
JD965_RS16180	COG2197	response regulator
JD965_RS16185	COG4585	Histidine kinase
JD965_RS16190	COG4758	membrane
JD965_RS16195	COG3595	metallopeptidase activity
JD965_RS16200	COG1842	Phage shock protein A
JD965_RS16205	COG4758	membrane
JD965_RS16210	COG2814	Major facilitator Superfamily
JD965_RS16215	COG2096	Adenosyltransferase
JD965_RS16220	COG1120	ATPase activity
JD965_RS16225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS16230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JD965_RS16235	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS16240	COG3386	PFAM SMP-30 Gluconolaconase
JD965_RS16245	COG2205	protein histidine kinase activity
JD965_RS16250	COG0745	RESPONSE REGULATOR receiver
JD965_RS16260	COG1191	sigma factor activity
JD965_RS16270	COG2140	Oxalate decarboxylase
JD965_RS16280	COG1120	ATPase activity
JD965_RS16285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS16290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS16295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JD965_RS16300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JD965_RS16305	COG0531	amino acid
JD965_RS16315	COG1988	membrane-bound metal-dependent
JD965_RS16320	COG1368	sulfuric ester hydrolase activity
JD965_RS16325	COG1910	domain protein
JD965_RS16330	COG0725	ABC transporter, periplasmic molybdate-binding protein
JD965_RS16335	COG4149	molybdate abc transporter
JD965_RS16340	COG2197	response regulator
JD965_RS16350	COG1131	(ABC) transporter
JD965_RS16360	COG0842	Transport permease protein
JD965_RS16375	COG0656	L-ascorbic acid biosynthetic process
JD965_RS16400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JD965_RS16405	COG3973	AAA domain
JD965_RS16410	COG2860	membrane
JD965_RS16420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JD965_RS16425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JD965_RS16430	COG2217	Heavy metal translocating P-type atpase
JD965_RS16435	COG2217	Heavy metal translocating P-type atpase
JD965_RS16440	COG2608	mercury ion transmembrane transporter activity
JD965_RS16445	COG1937	Protein conserved in bacteria
JD965_RS16450	COG0673	inositol 2-dehydrogenase activity
JD965_RS16460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS16465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JD965_RS16470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS16475	COG1126	abc transporter atp-binding protein
JD965_RS16480	COG0765	amino acid transport
JD965_RS16485	COG0765	amino acid transport
JD965_RS16490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JD965_RS16495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JD965_RS16500	COG0454	-acetyltransferase
JD965_RS16505	COG0583	DNA-binding transcription factor activity
JD965_RS16510	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS16515	COG2732	(Barnase) inhibitor
JD965_RS16535	COG0557	exoribonuclease II activity
JD965_RS16540	COG1647	Serine aminopeptidase, S33
JD965_RS16545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JD965_RS16550	COG1476	TRANSCRIPTIONal
JD965_RS16555	COG1396	sequence-specific DNA binding
JD965_RS16560	COG1396	sequence-specific DNA binding
JD965_RS16565	COG1733	regulation of RNA biosynthetic process
JD965_RS16590	COG1131	(ABC) transporter
JD965_RS16595	COG1174	glycine betaine transport
JD965_RS16600	COG1732	Glycine betaine
JD965_RS16605	COG1174	glycine betaine transport
JD965_RS16610	COG0517	IMP dehydrogenase activity
JD965_RS16610	COG1125	glycine betaine transport
JD965_RS16615	COG1510	regulation of RNA biosynthetic process
JD965_RS16620	COG1174	glycine betaine transport
JD965_RS16625	COG1732	Glycine betaine
JD965_RS16630	COG1174	glycine betaine transport
JD965_RS16635	COG0517	IMP dehydrogenase activity
JD965_RS16635	COG1125	glycine betaine transport
JD965_RS16640	COG1510	regulation of RNA biosynthetic process
JD965_RS16645	COG2095	MarC family integral membrane protein
JD965_RS16650	COG3064	Membrane
JD965_RS16655	COG4640	response to antibiotic
JD965_RS16660	COG0456	acetyltransferase
JD965_RS16680	COG0126	phosphoglycerate kinase activity
JD965_RS16685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JD965_RS16690	COG2390	Transcriptional regulator
JD965_RS16695	COG2814	Major facilitator Superfamily
JD965_RS16700	COG1609	Transcriptional regulator
JD965_RS16705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS16710	COG0583	DNA-binding transcription factor activity
JD965_RS16715	COG0697	spore germination
JD965_RS16720	COG1113	amino acid transport
JD965_RS16730	COG1609	Transcriptional regulator
JD965_RS16740	COG0561	phosphatase activity
JD965_RS16745	COG1737	Transcriptional regulator
JD965_RS16750	COG1070	Carbohydrate kinase
JD965_RS16770	COG2801	Transposase and inactivated derivatives
JD965_RS16800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JD965_RS16805	COG2186	Transcriptional regulator
JD965_RS16810	COG1620	l-lactate permease
JD965_RS16815	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
JD965_RS16825	COG5039	Polysaccharide pyruvyl transferase
JD965_RS16830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JD965_RS16835	COG0110	maltose O-acetyltransferase activity
JD965_RS16840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JD965_RS16845	COG2244	polysaccharide biosynthetic process
JD965_RS16850	COG1216	Glycosyl transferase, family 2
JD965_RS16855	COG5039	Polysaccharide pyruvyl transferase
JD965_RS16860	COG1216	Glycosyl transferase, family 2
JD965_RS16870	COG0438	transferase activity, transferring glycosyl groups
JD965_RS16875	COG1215	transferase activity, transferring glycosyl groups
JD965_RS16880	COG0438	transferase activity, transferring glycosyl groups
JD965_RS16885	COG1086	Polysaccharide biosynthesis protein
JD965_RS16890	COG0489	protein tyrosine kinase activity
JD965_RS16895	COG3944	biosynthesis protein
JD965_RS16900	COG1396	sequence-specific DNA binding
JD965_RS16905	COG2272	Belongs to the type-B carboxylesterase lipase family
JD965_RS16915	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JD965_RS16920	COG2364	Membrane
JD965_RS16925	COG0456	acetyltransferase
JD965_RS16930	COG3479	Phenolic acid decarboxylase
JD965_RS16960	COG1609	Transcriptional regulator
JD965_RS16970	COG0583	DNA-binding transcription factor activity
JD965_RS16975	COG2828	Protein conserved in bacteria
JD965_RS16980	COG0477	Major facilitator Superfamily
JD965_RS16980	COG2814	Major facilitator Superfamily
JD965_RS16990	COG1611	Belongs to the LOG family
JD965_RS16995	COG1694	Mazg nucleotide pyrophosphohydrolase
JD965_RS17005	COG0288	reversible hydration of carbon dioxide
JD965_RS17010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JD965_RS17015	COG4290	ribonuclease
JD965_RS17020	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JD965_RS17025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JD965_RS17035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JD965_RS17045	COG1051	belongs to the nudix hydrolase family
JD965_RS17050	COG0492	ferredoxin-NADP+ reductase activity
JD965_RS17055	COG0791	NLP P60 protein
JD965_RS17055	COG3883	PFAM NLP P60 protein
JD965_RS17060	COG0457	Tetratricopeptide repeat
JD965_RS17065	COG5002	protein histidine kinase activity
JD965_RS17070	COG0745	RESPONSE REGULATOR receiver
JD965_RS17080	COG1132	(ABC) transporter
JD965_RS17085	COG0140	phosphoribosyl-ATP diphosphatase activity
JD965_RS17085	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JD965_RS17110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JD965_RS17125	COG4990	cell redox homeostasis
JD965_RS17130	COG0110	maltose O-acetyltransferase activity
JD965_RS17150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JD965_RS17160	COG2188	Transcriptional regulator
JD965_RS17165	COG1309	transcriptional regulator
JD965_RS17170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JD965_RS17180	COG1950	PFAM Membrane protein of
JD965_RS17185	COG1983	PspC domain protein
JD965_RS17190	COG3595	metallopeptidase activity
JD965_RS17205	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JD965_RS17215	COG4897	Protein conserved in bacteria
JD965_RS17220	COG3848	Pyruvate phosphate dikinase
JD965_RS17220	COG0574	Belongs to the PEP-utilizing enzyme family
JD965_RS17225	COG1309	transcriptional regulator
JD965_RS17230	COG2814	Major facilitator Superfamily
JD965_RS17240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JD965_RS17250	COG3409	Peptidoglycan-binding domain 1 protein
JD965_RS17250	COG0793	Belongs to the peptidase S41A family
JD965_RS17255	COG3420	alginic acid biosynthetic process
JD965_RS17260	COG2177	Part of the ABC transporter FtsEX involved in
JD965_RS17265	COG2884	Cell division ATP-binding protein ftsE
JD965_RS17270	COG2010	Cytochrome c
JD965_RS17275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS17290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JD965_RS17305	COG1516	flagellar protein fliS
JD965_RS17310	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JD965_RS17315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JD965_RS17335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JD965_RS17340	COG1256	bacterial-type flagellum assembly
JD965_RS17340	COG4786	Flagellar basal body rod
JD965_RS17345	COG3418	PFAM FlgN family protein
JD965_RS17350	COG2747	anti-sigma28 factor FlgM
JD965_RS17360	COG1040	competence protein
JD965_RS17370	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JD965_RS17375	COG1307	EDD domain protein, DegV family
JD965_RS17380	COG2197	response regulator
JD965_RS17385	COG4585	Histidine kinase
JD965_RS17390	COG1739	Uncharacterized protein family UPF0029
JD965_RS17395	COG1316	TRANSCRIPTIONal
JD965_RS17400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JD965_RS17405	COG0438	transferase activity, transferring glycosyl groups
JD965_RS17410	COG1215	transferase activity, transferring glycosyl groups
JD965_RS17415	COG3206	protein involved in exopolysaccharide biosynthesis
JD965_RS17420	COG3307	-O-antigen
JD965_RS17425	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JD965_RS17430	COG0297	glycogen (starch) synthase activity
JD965_RS17430	COG0438	transferase activity, transferring glycosyl groups
JD965_RS17435	COG2244	polysaccharide biosynthetic process
JD965_RS17445	COG1316	TRANSCRIPTIONal
JD965_RS17450	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JD965_RS17455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JD965_RS17460	COG1134	teichoic acid transport
JD965_RS17465	COG1682	transport, permease protein
JD965_RS17470	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JD965_RS17480	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JD965_RS17485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JD965_RS17490	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
JD965_RS17495	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JD965_RS17500	COG4193	domain, Protein
JD965_RS17505	COG1216	Glycosyl transferase, family 2
JD965_RS17505	COG1442	glycosyl transferase family 8
JD965_RS17515	COG1181	Belongs to the D-alanine--D-alanine ligase family
JD965_RS17520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JD965_RS17520	COG0463	Glycosyl transferase, family 2
JD965_RS17530	COG1482	cell wall glycoprotein biosynthetic process
JD965_RS17535	COG0697	spore germination
JD965_RS17540	COG0814	amino acid
JD965_RS17550	COG0463	Glycosyl transferase, family 2
JD965_RS17555	COG2814	Major facilitator Superfamily
JD965_RS17560	COG1316	TRANSCRIPTIONal
JD965_RS17565	COG0561	phosphatase activity
JD965_RS17570	COG2433	Pfam Transposase IS66
JD965_RS17575	COG0791	NLP P60 protein
JD965_RS17585	COG2843	Capsule synthesis protein
JD965_RS17595	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JD965_RS17605	COG1609	Transcriptional regulator
JD965_RS17610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JD965_RS17620	COG1129	ABC transporter
JD965_RS17625	COG1172	Belongs to the binding-protein-dependent transport system permease family
JD965_RS17630	COG1879	ABC-type sugar transport system periplasmic component
JD965_RS17635	COG3103	Sh3 type 3 domain protein
JD965_RS17640	COG2249	NAD(P)H dehydrogenase (quinone) activity
JD965_RS17645	COG3527	Alpha-acetolactate decarboxylase
JD965_RS17650	COG0028	Belongs to the TPP enzyme family
JD965_RS17655	COG0583	DNA-binding transcription factor activity
JD965_RS17660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JD965_RS17675	COG5337	Spore coat protein CotH
JD965_RS17685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JD965_RS17695	COG0405	Gamma-glutamyltransferase
JD965_RS17700	COG1522	sequence-specific DNA binding
JD965_RS17705	COG2059	Chromate
JD965_RS17710	COG2059	Chromate
JD965_RS17720	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JD965_RS17725	COG4464	protein tyrosine phosphatase activity
JD965_RS17730	COG0489	protein tyrosine kinase activity
JD965_RS17735	COG3944	biosynthesis protein
JD965_RS17745	COG4715	Zinc finger, swim domain protein
JD965_RS17750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JD965_RS17755	COG0561	phosphatase activity
JD965_RS17760	COG1349	DNA-binding transcription factor activity
JD965_RS17765	COG0629	single-stranded DNA binding
JD965_RS17790	COG0457	Tetratricopeptide repeat
JD965_RS17795	COG4786	Flagellar basal body rod
JD965_RS17800	COG4786	Flagellar basal body rod
JD965_RS17805	COG1077	Cell shape determining protein MreB Mrl
JD965_RS17810	COG1609	Transcriptional regulator
JD965_RS17815	COG1846	Transcriptional regulator
JD965_RS17820	COG2814	Major facilitator Superfamily
JD965_RS17825	COG1953	Uracil, thiamine, allantoin
JD965_RS17830	COG0477	Major facilitator Superfamily
JD965_RS17835	COG1335	isochorismatase
JD965_RS17840	COG0004	ammonium transporteR
JD965_RS17845	COG0347	Belongs to the P(II) protein family
JD965_RS17850	COG0772	Belongs to the SEDS family
JD965_RS17855	COG0671	phosphoesterase, PA-phosphatase related
JD965_RS17865	COG0739	heme binding
JD965_RS17870	COG1247	-acetyltransferase
JD965_RS17885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JD965_RS17895	COG0726	polysaccharide deacetylase
JD965_RS17900	COG1959	2 iron, 2 sulfur cluster binding
JD965_RS17915	COG0831	urea catabolic process
JD965_RS17920	COG3237	CsbD-like
JD965_RS17925	COG1994	Peptidase M50
JD965_RS17930	COG0457	Tetratricopeptide repeat
JD965_RS17940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JD965_RS17950	COG2304	oxidoreductase activity
JD965_RS17955	COG2304	oxidoreductase activity
JD965_RS17960	COG2385	sporulation resulting in formation of a cellular spore
JD965_RS17965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JD965_RS17975	COG4836	Membrane
JD965_RS18045	COG0698	ribose 5-phosphate isomerase
JD965_RS18050	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JD965_RS18060	COG0009	L-threonylcarbamoyladenylate synthase
JD965_RS18065	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JD965_RS18085	COG2890	protein-(glutamine-N5) methyltransferase activity
JD965_RS18090	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JD965_RS18095	COG0346	lactoylglutathione lyase activity
JD965_RS18100	COG0789	Transcriptional regulator
JD965_RS18105	COG0679	Auxin Efflux Carrier
JD965_RS18110	COG0281	malic enzyme
JD965_RS18125	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JD965_RS18130	COG1494	fructose-1,6-bisphosphatase
JD965_RS18135	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JD965_RS18145	COG0191	fructose-bisphosphate aldolase activity
JD965_RS18150	COG2204	response regulator
JD965_RS18155	COG4821	SIS domain
JD965_RS18170	COG0247	lactate metabolic process
JD965_RS18170	COG2181	nitrate reductase activity
JD965_RS18175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JD965_RS18195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JD965_RS18205	COG2181	nitrate reductase activity
JD965_RS18210	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
JD965_RS18215	COG1140	nitrate reductase beta subunit
JD965_RS18220	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JD965_RS18225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JD965_RS18235	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JD965_RS18240	COG2223	nitrite transmembrane transporter activity
JD965_RS18250	COG4506	Protein conserved in bacteria
JD965_RS18255	COG3391	amine dehydrogenase activity
JD965_RS18260	COG0457	Tetratricopeptide repeat
JD965_RS18285	COG0010	Belongs to the arginase family
JD965_RS18290	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JD965_RS18295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JD965_RS18310	COG1994	Peptidase M50
JD965_RS18315	COG1942	4-Oxalocrotonate Tautomerase
JD965_RS18320	COG1846	Transcriptional regulator
JD965_RS18325	COG0531	amino acid
JD965_RS18330	COG3465	dGTPase activity
JD965_RS18335	COG1078	dGTPase activity
JD965_RS18350	COG1695	Transcriptional regulator
JD965_RS18370	COG0583	DNA-binding transcription factor activity
JD965_RS18375	COG2855	membrane
JD965_RS18380	COG0280	phosphate acetyltransferase
JD965_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS18405	COG2814	Major facilitator Superfamily
JD965_RS18410	COG2814	Major facilitator Superfamily
JD965_RS18415	COG0833	amino acid
JD965_RS18420	COG4187	Peptidase family M20/M25/M40
JD965_RS18425	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS18430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JD965_RS18435	COG2205	protein histidine kinase activity
JD965_RS18440	COG0745	RESPONSE REGULATOR receiver
JD965_RS18455	COG1131	(ABC) transporter
JD965_RS18460	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
JD965_RS18465	COG1091	dTDP-4-dehydrorhamnose reductase activity
JD965_RS18470	COG1088	dTDP-glucose 4,6-dehydratase activity
JD965_RS18475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JD965_RS18480	COG3980	spore coat polysaccharide biosynthesis protein
JD965_RS18485	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
JD965_RS18490	COG2089	acid synthase
JD965_RS18495	COG0456	acetyltransferase
JD965_RS18500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JD965_RS18505	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JD965_RS18510	COG0463	Glycosyl transferase, family 2
JD965_RS18520	COG2363	Small membrane protein
JD965_RS18525	COG2233	PERMEase
JD965_RS18540	COG1216	Glycosyl transferase, family 2
JD965_RS18555	COG1695	Transcriptional regulator
JD965_RS18560	COG0351	phosphomethylpyrimidine kinase
JD965_RS18570	COG1621	beta-fructofuranosidase activity
JD965_RS18575	COG1263	PTS System
JD965_RS18575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS18580	COG3711	transcriptional antiterminator
JD965_RS18590	COG1404	Belongs to the peptidase S8 family
JD965_RS18595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JD965_RS18600	COG2378	regulation of single-species biofilm formation
JD965_RS18620	COG0778	Nitroreductase
JD965_RS18625	COG0772	Belongs to the SEDS family
JD965_RS18630	COG0454	-acetyltransferase
JD965_RS18650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JD965_RS18655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JD965_RS18660	COG2261	transglycosylase associated protein
JD965_RS18665	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JD965_RS18670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JD965_RS18675	COG2246	polysaccharide biosynthetic process
JD965_RS18680	COG1309	transcriptional regulator
JD965_RS18690	COG2813	Specifically methylates the guanine in position
JD965_RS18700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JD965_RS18705	COG2837	iron assimilation
JD965_RS18710	COG2822	iron ion transport
JD965_RS18725	COG0583	DNA-binding transcription factor activity
JD965_RS18735	COG1346	cytolysis
JD965_RS18740	COG4895	conserved protein (DUF2196)
JD965_RS18745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JD965_RS18750	COG0346	lactoylglutathione lyase activity
JD965_RS18755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS18760	COG1404	Belongs to the peptidase S8 family
JD965_RS18765	COG1442	glycosyl transferase family 8
JD965_RS18770	COG2357	RelA SpoT domain protein
JD965_RS18775	COG1575	Belongs to the MenA family. Type 1 subfamily
JD965_RS18790	COG1696	Membrane protein involved in D-alanine export
JD965_RS18805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JD965_RS18810	COG1486	melibiose metabolic process
JD965_RS18815	COG1447	Phosphotransferase system cellobiose-specific component IIA
JD965_RS18820	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS18825	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JD965_RS18830	COG3711	transcriptional antiterminator
JD965_RS18830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JD965_RS18840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS18845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JD965_RS18855	COG0640	Transcriptional regulator
JD965_RS18860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JD965_RS18865	COG0753	catalase activity
JD965_RS18870	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
JD965_RS18875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JD965_RS18880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JD965_RS18885	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JD965_RS18890	COG4988	ABC transporter
JD965_RS18895	COG1294	oxidase, subunit
JD965_RS18900	COG1271	oxidase subunit
JD965_RS18905	COG3493	citrate carrier protein
JD965_RS18910	COG0726	polysaccharide deacetylase
JD965_RS18915	COG3842	ATPase activity
JD965_RS18920	COG2508	Transcriptional regulator
JD965_RS18925	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS18935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JD965_RS18950	COG4894	glucomannan catabolic process
JD965_RS18955	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JD965_RS18960	COG0500	methyltransferase
JD965_RS18965	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JD965_RS18980	COG0753	catalase activity
JD965_RS18980	COG0693	protein deglycase activity
JD965_RS18985	COG2851	Citrate transporter
JD965_RS18990	COG2273	Hydrolase Family 16
JD965_RS18995	COG3711	transcriptional antiterminator
JD965_RS19000	COG2270	Major facilitator Superfamily
JD965_RS19005	COG0513	Belongs to the DEAD box helicase family
JD965_RS19055	COG3209	COG3209 Rhs family protein
JD965_RS19065	COG0697	spore germination
JD965_RS19070	COG0589	response to stress
JD965_RS19075	COG2723	6-phospho-beta-galactosidase activity
JD965_RS19080	COG1263	PTS System
JD965_RS19080	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JD965_RS19080	COG2190	(PTS) system
JD965_RS19090	COG0494	nUDIX hydrolase
JD965_RS19100	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JD965_RS19105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JD965_RS19115	COG2390	Transcriptional regulator
JD965_RS19120	COG0561	phosphatase activity
JD965_RS19150	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JD965_RS19155	COG5294	Protein conserved in bacteria
JD965_RS19160	COG0577	efflux transmembrane transporter activity
JD965_RS19165	COG1136	(ABC) transporter
JD965_RS19170	COG2205	protein histidine kinase activity
JD965_RS19175	COG0745	RESPONSE REGULATOR receiver
JD965_RS19180	COG2205	protein histidine kinase activity
JD965_RS19185	COG0745	RESPONSE REGULATOR receiver
JD965_RS19205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JD965_RS19210	COG0191	fructose-bisphosphate aldolase activity
JD965_RS19215	COG1082	Xylose isomerase domain protein TIM barrel
JD965_RS19250	COG1349	DNA-binding transcription factor activity
JD965_RS19255	COG0667	Aldo Keto reductase
JD965_RS19260	COG2814	Major facilitator Superfamily
JD965_RS19270	COG1028	Short-chain dehydrogenase reductase Sdr
JD965_RS19275	COG2197	response regulator
JD965_RS19280	COG4585	Histidine kinase
JD965_RS19285	COG3239	Fatty acid desaturase
JD965_RS19290	COG1309	transcriptional regulator
JD965_RS19300	COG1476	TRANSCRIPTIONal
JD965_RS19330	COG1012	belongs to the aldehyde dehydrogenase family
JD965_RS19335	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JD965_RS19345	COG0640	Transcriptional regulator
JD965_RS19350	COG2814	Major facilitator Superfamily
JD965_RS19355	COG1714	RDD family
JD965_RS19365	COG0450	alkyl hydroperoxide reductase
JD965_RS19370	COG3634	alkyl hydroperoxide reductase activity
JD965_RS19375	COG1113	amino acid transport
JD965_RS19385	COG2080	2 iron, 2 sulfur cluster binding
JD965_RS19400	COG2068	MobA-Related Protein
JD965_RS19405	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JD965_RS19445	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JD965_RS19470	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JD965_RS19475	COG0456	acetyltransferase
JD965_RS19480	COG0457	Tetratricopeptide repeat
JD965_RS19485	COG0010	Belongs to the arginase family
JD965_RS19490	COG0833	amino acid
JD965_RS19495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JD965_RS19500	COG5658	integral membrane protein
JD965_RS19505	COG0640	Transcriptional regulator
JD965_RS19510	COG3829	transcription factor binding
JD965_RS19520	COG0488	(ABC) transporter
JD965_RS19535	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JD965_RS19550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JD965_RS19555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JD965_RS19560	COG4853	Protein conserved in bacteria
JD965_RS19565	COG4863	YycH protein
JD965_RS19570	COG5002	protein histidine kinase activity
JD965_RS19575	COG0745	RESPONSE REGULATOR receiver
JD965_RS19605	COG0346	lactoylglutathione lyase activity
JD965_RS19610	COG0305	Participates in initiation and elongation during chromosome replication
JD965_RS19625	COG3093	addiction module antidote protein HigA
JD965_RS19630	COG0438	transferase activity, transferring glycosyl groups
JD965_RS19640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JD965_RS19645	COG0438	transferase activity, transferring glycosyl groups
JD965_RS19665	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
JD965_RS19670	COG4241	membrane
JD965_RS19680	COG5577	PFAM Coat F domain
JD965_RS19685	COG1733	regulation of RNA biosynthetic process
JD965_RS19710	COG0697	spore germination
JD965_RS19715	COG1621	beta-fructofuranosidase activity
JD965_RS19720	COG1621	beta-fructofuranosidase activity
JD965_RS19725	COG1802	Transcriptional regulator
JD965_RS19730	COG2318	DinB family
JD965_RS19735	COG2211	Major facilitator Superfamily
JD965_RS19745	COG2197	response regulator
JD965_RS19750	COG0512	Glutamine amidotransferase of anthranilate synthase
JD965_RS19750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JD965_RS19755	COG0697	spore germination
JD965_RS19760	COG0583	DNA-binding transcription factor activity
JD965_RS19770	COG0778	Nitroreductase
JD965_RS19775	COG1846	Transcriptional regulator
JD965_RS19780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JD965_RS19785	COG1846	Transcriptional regulator
JD965_RS19790	COG2153	protein acetylation
JD965_RS19800	COG1078	dGTPase activity
JD965_RS19805	COG1331	Highly conserved protein containing a thioredoxin domain
JD965_RS19815	COG0457	Tetratricopeptide repeat
JD965_RS19840	COG0741	lytic transglycosylase activity
JD965_RS19840	COG0791	NLP P60 protein
JD965_RS19845	COG5644	endopeptidase inhibitor activity
JD965_RS19855	COG0433	COG0433 Predicted ATPase
JD965_RS19905	COG2946	Replication initiation factor
JD965_RS19910	COG1674	ftsk spoiiie
JD965_RS19935	COG1396	sequence-specific DNA binding
JD965_RS19940	COG2856	Zn peptidase
JD965_RS19960	COG1331	Highly conserved protein containing a thioredoxin domain
JD965_RS19965	COG1331	Highly conserved protein containing a thioredoxin domain
JD965_RS19970	COG1266	CAAX protease self-immunity
JD965_RS19975	COG2814	Major facilitator Superfamily
JD965_RS19975	COG0477	Major facilitator Superfamily
JD965_RS19980	COG0346	lactoylglutathione lyase activity
JD965_RS19985	COG1609	Transcriptional regulator
JD965_RS19990	COG0708	Exodeoxyribonuclease III
JD965_RS19995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JD965_RS20000	COG2169	Transcriptional regulator
JD965_RS20010	COG0629	single-stranded DNA binding
JD965_RS20020	COG0012	GTP binding
JD965_RS20025	COG0243	molybdopterin cofactor binding
JD965_RS20030	COG4481	Protein conserved in bacteria
JD965_RS20035	COG3949	Membrane
JD965_RS20050	COG1475	DNA binding
JD965_RS20055	COG1192	Involved in chromosome partitioning
JD965_RS20080	COG1847	R3H domain protein
JD965_RS20085	COG0706	membrane insertase activity