locus-tag	class	description
CWD84_RS00020	COG0706	membrane insertase activity
CWD84_RS00025	COG1847	R3H domain protein
CWD84_RS00050	COG1192	Involved in chromosome partitioning
CWD84_RS00055	COG1475	DNA binding
CWD84_RS00070	COG3949	Membrane
CWD84_RS00075	COG4481	Protein conserved in bacteria
CWD84_RS00080	COG0243	molybdopterin cofactor binding
CWD84_RS00085	COG0012	GTP binding
CWD84_RS00095	COG0629	single-stranded DNA binding
CWD84_RS00105	COG2169	Transcriptional regulator
CWD84_RS00110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWD84_RS00115	COG0708	Exodeoxyribonuclease III
CWD84_RS00120	COG1609	Transcriptional regulator
CWD84_RS00125	COG0346	lactoylglutathione lyase activity
CWD84_RS00130	COG2814	Major facilitator Superfamily
CWD84_RS00130	COG0477	Major facilitator Superfamily
CWD84_RS00135	COG1266	CAAX protease self-immunity
CWD84_RS00140	COG1331	Highly conserved protein containing a thioredoxin domain
CWD84_RS00145	COG1331	Highly conserved protein containing a thioredoxin domain
CWD84_RS00150	COG2856	Zn peptidase
CWD84_RS00155	COG1396	sequence-specific DNA binding
CWD84_RS00185	COG1674	ftsk spoiiie
CWD84_RS00190	COG2946	Replication initiation factor
CWD84_RS00235	COG0433	COG0433 Predicted ATPase
CWD84_RS00245	COG5644	endopeptidase inhibitor activity
CWD84_RS00250	COG0741	lytic transglycosylase activity
CWD84_RS00250	COG0791	NLP P60 protein
CWD84_RS00270	COG0457	Tetratricopeptide repeat
CWD84_RS00280	COG1331	Highly conserved protein containing a thioredoxin domain
CWD84_RS00290	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWD84_RS00300	COG1131	(ABC) transporter
CWD84_RS00340	COG0697	spore germination
CWD84_RS00345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWD84_RS00350	COG2153	protein acetylation
CWD84_RS00355	COG1846	Transcriptional regulator
CWD84_RS00360	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS00365	COG1846	Transcriptional regulator
CWD84_RS00370	COG0778	Nitroreductase
CWD84_RS00380	COG0583	DNA-binding transcription factor activity
CWD84_RS00385	COG2211	Major facilitator Superfamily
CWD84_RS00390	COG2318	DinB family
CWD84_RS00395	COG1802	Transcriptional regulator
CWD84_RS00400	COG1621	beta-fructofuranosidase activity
CWD84_RS00405	COG1621	beta-fructofuranosidase activity
CWD84_RS00410	COG0697	spore germination
CWD84_RS00420	COG1733	regulation of RNA biosynthetic process
CWD84_RS00425	COG5577	PFAM Coat F domain
CWD84_RS00435	COG4241	membrane
CWD84_RS00440	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CWD84_RS00460	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS00465	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CWD84_RS00475	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS00480	COG3093	addiction module antidote protein HigA
CWD84_RS00495	COG0305	Participates in initiation and elongation during chromosome replication
CWD84_RS00500	COG0346	lactoylglutathione lyase activity
CWD84_RS00535	COG0745	RESPONSE REGULATOR receiver
CWD84_RS00540	COG5002	protein histidine kinase activity
CWD84_RS00545	COG4863	YycH protein
CWD84_RS00550	COG4853	Protein conserved in bacteria
CWD84_RS00555	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWD84_RS00560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWD84_RS00575	COG3829	transcription factor binding
CWD84_RS00580	COG0640	Transcriptional regulator
CWD84_RS00585	COG5658	integral membrane protein
CWD84_RS00590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWD84_RS00595	COG0833	amino acid
CWD84_RS00600	COG0010	Belongs to the arginase family
CWD84_RS00605	COG0457	Tetratricopeptide repeat
CWD84_RS00610	COG0456	acetyltransferase
CWD84_RS00615	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CWD84_RS00675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CWD84_RS00680	COG2068	MobA-Related Protein
CWD84_RS00695	COG2080	2 iron, 2 sulfur cluster binding
CWD84_RS00705	COG1113	amino acid transport
CWD84_RS00710	COG3634	alkyl hydroperoxide reductase activity
CWD84_RS00715	COG0450	alkyl hydroperoxide reductase
CWD84_RS00725	COG1714	RDD family
CWD84_RS00730	COG2814	Major facilitator Superfamily
CWD84_RS00735	COG0640	Transcriptional regulator
CWD84_RS00745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWD84_RS00750	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS00755	COG1309	transcriptional regulator
CWD84_RS00760	COG3239	Fatty acid desaturase
CWD84_RS00765	COG4585	Histidine kinase
CWD84_RS00770	COG2197	response regulator
CWD84_RS00775	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS00790	COG2814	Major facilitator Superfamily
CWD84_RS00795	COG0667	Aldo Keto reductase
CWD84_RS00800	COG1349	DNA-binding transcription factor activity
CWD84_RS00840	COG1082	Xylose isomerase domain protein TIM barrel
CWD84_RS00850	COG0191	fructose-bisphosphate aldolase activity
CWD84_RS00855	COG0745	RESPONSE REGULATOR receiver
CWD84_RS00860	COG2205	protein histidine kinase activity
CWD84_RS00865	COG1136	(ABC) transporter
CWD84_RS00870	COG0577	efflux transmembrane transporter activity
CWD84_RS00875	COG5294	Protein conserved in bacteria
CWD84_RS00880	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS00910	COG0561	phosphatase activity
CWD84_RS00915	COG2390	Transcriptional regulator
CWD84_RS00925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWD84_RS00930	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CWD84_RS00955	COG2723	6-phospho-beta-galactosidase activity
CWD84_RS00960	COG0589	response to stress
CWD84_RS00965	COG0697	spore germination
CWD84_RS00975	COG3209	COG3209 Rhs family protein
CWD84_RS01055	COG0513	Belongs to the DEAD box helicase family
CWD84_RS01060	COG2270	Major facilitator Superfamily
CWD84_RS01065	COG3711	transcriptional antiterminator
CWD84_RS01070	COG2273	Hydrolase Family 16
CWD84_RS01075	COG2851	Citrate transporter
CWD84_RS01080	COG0693	protein deglycase activity
CWD84_RS01080	COG0753	catalase activity
CWD84_RS01095	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWD84_RS01100	COG0500	methyltransferase
CWD84_RS01105	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWD84_RS01110	COG4894	glucomannan catabolic process
CWD84_RS01120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWD84_RS01130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS01135	COG2508	Transcriptional regulator
CWD84_RS01140	COG3842	ATPase activity
CWD84_RS01145	COG0726	polysaccharide deacetylase
CWD84_RS01150	COG3493	citrate carrier protein
CWD84_RS01155	COG1271	oxidase subunit
CWD84_RS01160	COG1294	oxidase, subunit
CWD84_RS01165	COG4988	ABC transporter
CWD84_RS01170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CWD84_RS01175	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWD84_RS01180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CWD84_RS01185	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CWD84_RS01190	COG0753	catalase activity
CWD84_RS01195	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CWD84_RS01200	COG0640	Transcriptional regulator
CWD84_RS01205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS01210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS01215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS01230	COG3711	transcriptional antiterminator
CWD84_RS01230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWD84_RS01235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWD84_RS01240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWD84_RS01245	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWD84_RS01250	COG1486	melibiose metabolic process
CWD84_RS01275	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS01285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS01290	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CWD84_RS01300	COG1696	Membrane protein involved in D-alanine export
CWD84_RS01325	COG1575	Belongs to the MenA family. Type 1 subfamily
CWD84_RS01330	COG2357	RelA SpoT domain protein
CWD84_RS01335	COG1442	glycosyl transferase family 8
CWD84_RS01340	COG1404	Belongs to the peptidase S8 family
CWD84_RS01345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWD84_RS01350	COG0346	lactoylglutathione lyase activity
CWD84_RS01355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWD84_RS01360	COG4895	conserved protein (DUF2196)
CWD84_RS01365	COG1346	cytolysis
CWD84_RS01375	COG0583	DNA-binding transcription factor activity
CWD84_RS01390	COG0672	)-iron permease
CWD84_RS01395	COG2822	iron ion transport
CWD84_RS01400	COG2837	iron assimilation
CWD84_RS01405	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CWD84_RS01415	COG2813	Specifically methylates the guanine in position
CWD84_RS01425	COG1309	transcriptional regulator
CWD84_RS01430	COG2246	polysaccharide biosynthetic process
CWD84_RS01435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWD84_RS01440	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWD84_RS01445	COG2261	transglycosylase associated protein
CWD84_RS01450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWD84_RS01455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWD84_RS01475	COG0454	-acetyltransferase
CWD84_RS01480	COG0772	Belongs to the SEDS family
CWD84_RS01485	COG0778	Nitroreductase
CWD84_RS01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWD84_RS01495	COG1404	Belongs to the peptidase S8 family
CWD84_RS01505	COG3711	transcriptional antiterminator
CWD84_RS01510	COG1263	PTS System
CWD84_RS01510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWD84_RS01515	COG1621	beta-fructofuranosidase activity
CWD84_RS01525	COG0351	phosphomethylpyrimidine kinase
CWD84_RS01530	COG1695	Transcriptional regulator
CWD84_RS01545	COG1216	Glycosyl transferase, family 2
CWD84_RS01560	COG2233	PERMEase
CWD84_RS01565	COG2363	Small membrane protein
CWD84_RS01575	COG0463	Glycosyl transferase, family 2
CWD84_RS01580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CWD84_RS01585	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWD84_RS01590	COG0456	acetyltransferase
CWD84_RS01595	COG2089	acid synthase
CWD84_RS01600	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
CWD84_RS01605	COG3980	spore coat polysaccharide biosynthesis protein
CWD84_RS01610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWD84_RS01615	COG1088	dTDP-glucose 4,6-dehydratase activity
CWD84_RS01620	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWD84_RS01625	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CWD84_RS01630	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWD84_RS01635	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS01640	COG4187	Peptidase family M20/M25/M40
CWD84_RS01645	COG0833	amino acid
CWD84_RS01650	COG2814	Major facilitator Superfamily
CWD84_RS01655	COG2814	Major facilitator Superfamily
CWD84_RS01685	COG0436	Aminotransferase
CWD84_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS01700	COG0280	phosphate acetyltransferase
CWD84_RS01705	COG2855	membrane
CWD84_RS01710	COG0583	DNA-binding transcription factor activity
CWD84_RS01740	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CWD84_RS01745	COG1131	(ABC) transporter
CWD84_RS01755	COG1695	Transcriptional regulator
CWD84_RS01770	COG1078	dGTPase activity
CWD84_RS01775	COG3465	dGTPase activity
CWD84_RS01780	COG0531	amino acid
CWD84_RS01790	COG1846	Transcriptional regulator
CWD84_RS01795	COG1942	4-Oxalocrotonate Tautomerase
CWD84_RS01800	COG1994	Peptidase M50
CWD84_RS01815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWD84_RS01820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CWD84_RS01825	COG0010	Belongs to the arginase family
CWD84_RS01835	COG0457	Tetratricopeptide repeat
CWD84_RS01840	COG4506	Protein conserved in bacteria
CWD84_RS01850	COG2223	nitrite transmembrane transporter activity
CWD84_RS01855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWD84_RS01865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWD84_RS01870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CWD84_RS01875	COG1140	nitrate reductase beta subunit
CWD84_RS01880	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CWD84_RS01885	COG2181	nitrate reductase activity
CWD84_RS01895	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWD84_RS01900	COG1132	(ABC) transporter
CWD84_RS01915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWD84_RS01920	COG0247	lactate metabolic process
CWD84_RS01920	COG2181	nitrate reductase activity
CWD84_RS01935	COG4821	SIS domain
CWD84_RS01940	COG2204	response regulator
CWD84_RS01945	COG0191	fructose-bisphosphate aldolase activity
CWD84_RS01955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWD84_RS01960	COG1494	fructose-1,6-bisphosphatase
CWD84_RS01970	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CWD84_RS01985	COG0281	malic enzyme
CWD84_RS01990	COG0679	Auxin Efflux Carrier
CWD84_RS01995	COG0789	Transcriptional regulator
CWD84_RS02000	COG0346	lactoylglutathione lyase activity
CWD84_RS02005	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWD84_RS02010	COG2890	protein-(glutamine-N5) methyltransferase activity
CWD84_RS02030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CWD84_RS02035	COG0009	L-threonylcarbamoyladenylate synthase
CWD84_RS02045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWD84_RS02050	COG0698	ribose 5-phosphate isomerase
CWD84_RS02120	COG4836	Membrane
CWD84_RS02130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWD84_RS02135	COG2385	sporulation resulting in formation of a cellular spore
CWD84_RS02145	COG2304	oxidoreductase activity
CWD84_RS02150	COG2304	oxidoreductase activity
CWD84_RS02155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CWD84_RS02165	COG0457	Tetratricopeptide repeat
CWD84_RS02170	COG1994	Peptidase M50
CWD84_RS02175	COG3237	CsbD-like
CWD84_RS02180	COG0831	urea catabolic process
CWD84_RS02195	COG1959	2 iron, 2 sulfur cluster binding
CWD84_RS02200	COG0726	polysaccharide deacetylase
CWD84_RS02210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWD84_RS02225	COG1247	-acetyltransferase
CWD84_RS02230	COG0739	heme binding
CWD84_RS02240	COG0671	phosphoesterase, PA-phosphatase related
CWD84_RS02245	COG0772	Belongs to the SEDS family
CWD84_RS02250	COG0347	Belongs to the P(II) protein family
CWD84_RS02255	COG0004	ammonium transporteR
CWD84_RS02260	COG1335	isochorismatase
CWD84_RS02265	COG0477	Major facilitator Superfamily
CWD84_RS02270	COG1953	Uracil, thiamine, allantoin
CWD84_RS02275	COG2814	Major facilitator Superfamily
CWD84_RS02280	COG1846	Transcriptional regulator
CWD84_RS02285	COG1609	Transcriptional regulator
CWD84_RS02290	COG1077	Cell shape determining protein MreB Mrl
CWD84_RS02295	COG4786	Flagellar basal body rod
CWD84_RS02300	COG4786	Flagellar basal body rod
CWD84_RS02305	COG0457	Tetratricopeptide repeat
CWD84_RS02330	COG0629	single-stranded DNA binding
CWD84_RS02335	COG1349	DNA-binding transcription factor activity
CWD84_RS02340	COG0561	phosphatase activity
CWD84_RS02345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWD84_RS02350	COG4715	Zinc finger, swim domain protein
CWD84_RS02360	COG3944	biosynthesis protein
CWD84_RS02365	COG0489	protein tyrosine kinase activity
CWD84_RS02370	COG4464	protein tyrosine phosphatase activity
CWD84_RS02375	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CWD84_RS02390	COG5444	nuclease activity
CWD84_RS02410	COG2059	Chromate
CWD84_RS02415	COG2059	Chromate
CWD84_RS02420	COG1522	sequence-specific DNA binding
CWD84_RS02425	COG0405	Gamma-glutamyltransferase
CWD84_RS02435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWD84_RS02445	COG5337	Spore coat protein CotH
CWD84_RS02460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CWD84_RS02465	COG0583	DNA-binding transcription factor activity
CWD84_RS02470	COG0028	Belongs to the TPP enzyme family
CWD84_RS02475	COG3527	Alpha-acetolactate decarboxylase
CWD84_RS02480	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWD84_RS02485	COG3103	Sh3 type 3 domain protein
CWD84_RS02490	COG1879	ABC-type sugar transport system periplasmic component
CWD84_RS02495	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWD84_RS02500	COG1129	ABC transporter
CWD84_RS02510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWD84_RS02515	COG1609	Transcriptional regulator
CWD84_RS02530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CWD84_RS02540	COG2843	Capsule synthesis protein
CWD84_RS02555	COG0791	NLP P60 protein
CWD84_RS02560	COG2433	Pfam Transposase IS66
CWD84_RS02565	COG0561	phosphatase activity
CWD84_RS02570	COG1316	TRANSCRIPTIONal
CWD84_RS02575	COG2814	Major facilitator Superfamily
CWD84_RS02580	COG0463	Glycosyl transferase, family 2
CWD84_RS02590	COG0814	amino acid
CWD84_RS02595	COG0697	spore germination
CWD84_RS02600	COG1482	cell wall glycoprotein biosynthetic process
CWD84_RS02605	COG4193	domain, Protein
CWD84_RS02610	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CWD84_RS02615	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CWD84_RS02620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWD84_RS02630	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CWD84_RS02635	COG1682	transport, permease protein
CWD84_RS02640	COG1134	teichoic acid transport
CWD84_RS02645	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWD84_RS02650	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CWD84_RS02655	COG1316	TRANSCRIPTIONal
CWD84_RS02665	COG2385	sporulation resulting in formation of a cellular spore
CWD84_RS02665	COG2247	cell wall binding repeat
CWD84_RS02670	COG2247	cell wall binding repeat
CWD84_RS02670	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS02680	COG2244	polysaccharide biosynthetic process
CWD84_RS02685	COG0297	glycogen (starch) synthase activity
CWD84_RS02685	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS02690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CWD84_RS02695	COG3307	-O-antigen
CWD84_RS02700	COG3206	protein involved in exopolysaccharide biosynthesis
CWD84_RS02705	COG1215	transferase activity, transferring glycosyl groups
CWD84_RS02710	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS02715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWD84_RS02720	COG1316	TRANSCRIPTIONal
CWD84_RS02725	COG1739	Uncharacterized protein family UPF0029
CWD84_RS02730	COG4585	Histidine kinase
CWD84_RS02735	COG2197	response regulator
CWD84_RS02740	COG1307	EDD domain protein, DegV family
CWD84_RS02745	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CWD84_RS02755	COG1040	competence protein
CWD84_RS02765	COG2747	anti-sigma28 factor FlgM
CWD84_RS02770	COG3418	PFAM FlgN family protein
CWD84_RS02775	COG1256	bacterial-type flagellum assembly
CWD84_RS02775	COG4786	Flagellar basal body rod
CWD84_RS02780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CWD84_RS02800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CWD84_RS02805	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CWD84_RS02810	COG1516	flagellar protein fliS
CWD84_RS02825	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CWD84_RS02840	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS02845	COG2010	Cytochrome c
CWD84_RS02850	COG2884	Cell division ATP-binding protein ftsE
CWD84_RS02855	COG2177	Part of the ABC transporter FtsEX involved in
CWD84_RS02860	COG3420	alginic acid biosynthetic process
CWD84_RS02865	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS02865	COG0793	Belongs to the peptidase S41A family
CWD84_RS02875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWD84_RS02885	COG2814	Major facilitator Superfamily
CWD84_RS02890	COG1309	transcriptional regulator
CWD84_RS02895	COG3848	Pyruvate phosphate dikinase
CWD84_RS02895	COG0574	Belongs to the PEP-utilizing enzyme family
CWD84_RS02900	COG4897	Protein conserved in bacteria
CWD84_RS02910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWD84_RS02925	COG3595	metallopeptidase activity
CWD84_RS02930	COG1983	PspC domain protein
CWD84_RS02935	COG1950	PFAM Membrane protein of
CWD84_RS02940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWD84_RS02945	COG1309	transcriptional regulator
CWD84_RS02950	COG2188	Transcriptional regulator
CWD84_RS02960	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CWD84_RS02980	COG0110	maltose O-acetyltransferase activity
CWD84_RS02985	COG4990	cell redox homeostasis
CWD84_RS03000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CWD84_RS03025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CWD84_RS03025	COG0140	phosphoribosyl-ATP diphosphatase activity
CWD84_RS03030	COG1132	(ABC) transporter
CWD84_RS03040	COG0745	RESPONSE REGULATOR receiver
CWD84_RS03045	COG5002	protein histidine kinase activity
CWD84_RS03050	COG0457	Tetratricopeptide repeat
CWD84_RS03060	COG3883	PFAM NLP P60 protein
CWD84_RS03060	COG0791	NLP P60 protein
CWD84_RS03065	COG0492	ferredoxin-NADP+ reductase activity
CWD84_RS03070	COG1051	belongs to the nudix hydrolase family
CWD84_RS03080	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CWD84_RS03090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWD84_RS03095	COG2162	N-hydroxyarylamine O-acetyltransferase activity
CWD84_RS03100	COG4290	ribonuclease
CWD84_RS03105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWD84_RS03115	COG0288	reversible hydration of carbon dioxide
CWD84_RS03120	COG0659	secondary active sulfate transmembrane transporter activity
CWD84_RS03125	COG1694	Mazg nucleotide pyrophosphohydrolase
CWD84_RS03130	COG1611	Belongs to the LOG family
CWD84_RS03140	COG0477	Major facilitator Superfamily
CWD84_RS03140	COG2814	Major facilitator Superfamily
CWD84_RS03145	COG2828	Protein conserved in bacteria
CWD84_RS03150	COG0583	DNA-binding transcription factor activity
CWD84_RS03160	COG1609	Transcriptional regulator
CWD84_RS03240	COG3479	Phenolic acid decarboxylase
CWD84_RS03245	COG0456	acetyltransferase
CWD84_RS03250	COG2364	Membrane
CWD84_RS03255	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWD84_RS03265	COG2272	Belongs to the type-B carboxylesterase lipase family
CWD84_RS03270	COG1396	sequence-specific DNA binding
CWD84_RS03275	COG3944	biosynthesis protein
CWD84_RS03280	COG0489	protein tyrosine kinase activity
CWD84_RS03285	COG1086	Polysaccharide biosynthesis protein
CWD84_RS03290	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS03295	COG1215	transferase activity, transferring glycosyl groups
CWD84_RS03300	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS03310	COG1216	Glycosyl transferase, family 2
CWD84_RS03315	COG5039	Polysaccharide pyruvyl transferase
CWD84_RS03320	COG1216	Glycosyl transferase, family 2
CWD84_RS03325	COG2244	polysaccharide biosynthetic process
CWD84_RS03330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWD84_RS03335	COG0110	maltose O-acetyltransferase activity
CWD84_RS03340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWD84_RS03345	COG5039	Polysaccharide pyruvyl transferase
CWD84_RS03355	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWD84_RS03360	COG1620	l-lactate permease
CWD84_RS03365	COG2186	Transcriptional regulator
CWD84_RS03370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWD84_RS03395	COG1070	Carbohydrate kinase
CWD84_RS03400	COG1737	Transcriptional regulator
CWD84_RS03405	COG1113	amino acid transport
CWD84_RS03415	COG0697	spore germination
CWD84_RS03420	COG0583	DNA-binding transcription factor activity
CWD84_RS03430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWD84_RS03435	COG1609	Transcriptional regulator
CWD84_RS03445	COG2390	Transcriptional regulator
CWD84_RS03450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWD84_RS03460	COG0126	phosphoglycerate kinase activity
CWD84_RS03480	COG0456	acetyltransferase
CWD84_RS03485	COG4640	response to antibiotic
CWD84_RS03490	COG3064	Membrane
CWD84_RS03505	COG2095	MarC family integral membrane protein
CWD84_RS03510	COG1510	regulation of RNA biosynthetic process
CWD84_RS03515	COG1125	glycine betaine transport
CWD84_RS03515	COG0517	IMP dehydrogenase activity
CWD84_RS03520	COG1174	glycine betaine transport
CWD84_RS03525	COG1732	Glycine betaine
CWD84_RS03530	COG1174	glycine betaine transport
CWD84_RS03535	COG1510	regulation of RNA biosynthetic process
CWD84_RS03540	COG1125	glycine betaine transport
CWD84_RS03540	COG0517	IMP dehydrogenase activity
CWD84_RS03550	COG1732	Glycine betaine
CWD84_RS03555	COG1174	glycine betaine transport
CWD84_RS03560	COG1131	(ABC) transporter
CWD84_RS03585	COG1733	regulation of RNA biosynthetic process
CWD84_RS03590	COG1396	sequence-specific DNA binding
CWD84_RS03595	COG1396	sequence-specific DNA binding
CWD84_RS03600	COG1476	TRANSCRIPTIONal
CWD84_RS03605	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWD84_RS03610	COG1647	Serine aminopeptidase, S33
CWD84_RS03615	COG0557	exoribonuclease II activity
CWD84_RS03645	COG2732	(Barnase) inhibitor
CWD84_RS03650	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS03655	COG0583	DNA-binding transcription factor activity
CWD84_RS03660	COG0454	-acetyltransferase
CWD84_RS03665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS03670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS03675	COG0765	amino acid transport
CWD84_RS03680	COG0765	amino acid transport
CWD84_RS03685	COG1126	abc transporter atp-binding protein
CWD84_RS03690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWD84_RS03695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWD84_RS03700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWD84_RS03715	COG2814	Major facilitator Superfamily
CWD84_RS03735	COG0673	inositol 2-dehydrogenase activity
CWD84_RS03740	COG1937	Protein conserved in bacteria
CWD84_RS03745	COG2608	mercury ion transmembrane transporter activity
CWD84_RS03750	COG2217	Heavy metal translocating P-type atpase
CWD84_RS03755	COG2217	Heavy metal translocating P-type atpase
CWD84_RS03760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CWD84_RS03765	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CWD84_RS03775	COG2860	membrane
CWD84_RS03780	COG3973	AAA domain
CWD84_RS03785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CWD84_RS03810	COG0656	L-ascorbic acid biosynthetic process
CWD84_RS03815	COG0842	Transport permease protein
CWD84_RS03825	COG1131	(ABC) transporter
CWD84_RS03830	COG3850	Histidine kinase
CWD84_RS03835	COG2197	response regulator
CWD84_RS03840	COG4149	molybdate abc transporter
CWD84_RS03845	COG0725	ABC transporter, periplasmic molybdate-binding protein
CWD84_RS03850	COG1910	domain protein
CWD84_RS03860	COG1368	sulfuric ester hydrolase activity
CWD84_RS03865	COG1988	membrane-bound metal-dependent
CWD84_RS03880	COG0531	amino acid
CWD84_RS03885	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CWD84_RS03890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS03900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS03905	COG1120	ATPase activity
CWD84_RS03915	COG2140	Oxalate decarboxylase
CWD84_RS03930	COG1191	sigma factor activity
CWD84_RS03940	COG0745	RESPONSE REGULATOR receiver
CWD84_RS03945	COG2205	protein histidine kinase activity
CWD84_RS03950	COG3386	PFAM SMP-30 Gluconolaconase
CWD84_RS03955	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS03960	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS03965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS03970	COG1120	ATPase activity
CWD84_RS03975	COG2096	Adenosyltransferase
CWD84_RS03980	COG2814	Major facilitator Superfamily
CWD84_RS03985	COG4758	membrane
CWD84_RS03990	COG1842	Phage shock protein A
CWD84_RS03995	COG3595	metallopeptidase activity
CWD84_RS04000	COG4758	membrane
CWD84_RS04005	COG4585	Histidine kinase
CWD84_RS04010	COG2197	response regulator
CWD84_RS04020	COG0814	amino acid
CWD84_RS04025	COG0697	spore germination
CWD84_RS04035	COG0114	fumarate hydratase activity
CWD84_RS04040	COG1309	transcriptional regulator
CWD84_RS04050	COG2770	Histidine kinase
CWD84_RS04050	COG2205	protein histidine kinase activity
CWD84_RS04055	COG0745	RESPONSE REGULATOR receiver
CWD84_RS04060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWD84_RS04065	COG0783	Belongs to the Dps family
CWD84_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS04085	COG1120	ATPase activity
CWD84_RS04105	COG1942	4-Oxalocrotonate Tautomerase
CWD84_RS04110	COG0477	Major facilitator Superfamily
CWD84_RS04115	COG1846	Transcriptional regulator
CWD84_RS04120	COG5577	PFAM Coat F domain
CWD84_RS04140	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWD84_RS04140	COG1024	Enoyl-CoA hydratase
CWD84_RS04145	COG0183	Belongs to the thiolase family
CWD84_RS04150	COG1960	acyl-CoA dehydrogenase activity
CWD84_RS04155	COG1393	Belongs to the ArsC family
CWD84_RS04170	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CWD84_RS04175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS04185	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWD84_RS04190	COG2011	ABC-type metal ion transport system permease component
CWD84_RS04195	COG1464	Belongs to the NlpA lipoprotein family
CWD84_RS04200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWD84_RS04210	COG0396	ATPase activity
CWD84_RS04215	COG0719	Fe-S assembly protein
CWD84_RS04220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWD84_RS04225	COG0822	iron-sulfur transferase activity
CWD84_RS04230	COG0719	Fe-S assembly protein
CWD84_RS04270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWD84_RS04285	COG2323	membrane
CWD84_RS04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWD84_RS04325	COG0322	excinuclease ABC activity
CWD84_RS04350	COG0789	Transcriptional regulator
CWD84_RS04355	COG2222	sugar isomerase
CWD84_RS04360	COG1653	transport
CWD84_RS04365	COG1175	transmembrane transport
CWD84_RS04370	COG0395	ABC-type sugar transport system, permease component
CWD84_RS04375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWD84_RS04380	COG2188	Transcriptional regulator
CWD84_RS04385	COG3842	ATPase activity
CWD84_RS04395	COG1116	anion transmembrane transporter activity
CWD84_RS04400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWD84_RS04405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWD84_RS04415	COG2356	endonuclease I
CWD84_RS04420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWD84_RS04425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CWD84_RS04430	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CWD84_RS04435	COG2068	MobA-Related Protein
CWD84_RS04440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CWD84_RS04445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWD84_RS04450	COG2080	2 iron, 2 sulfur cluster binding
CWD84_RS04455	COG1794	racemase activity, acting on amino acids and derivatives
CWD84_RS04460	COG2351	hydroxyisourate hydrolase activity
CWD84_RS04465	COG3648	Uricase
CWD84_RS04465	COG3195	allantoin biosynthetic process
CWD84_RS04470	COG2233	PERMEase
CWD84_RS04475	COG2233	PERMEase
CWD84_RS04480	COG2508	Transcriptional regulator
CWD84_RS04485	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWD84_RS04495	COG1801	Protein of unknown function DUF72
CWD84_RS04500	COG0730	response to heat
CWD84_RS04505	COG0737	Belongs to the 5'-nucleotidase family
CWD84_RS04515	COG0739	heme binding
CWD84_RS04530	COG4470	Protein conserved in bacteria
CWD84_RS04535	COG2445	Protein of unknown function DUF86
CWD84_RS04540	COG0647	UMP catabolic process
CWD84_RS04545	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWD84_RS04550	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CWD84_RS04560	COG0460	homoserine dehydrogenase
CWD84_RS04565	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CWD84_RS04575	COG4946	Tricorn protease homolog
CWD84_RS04575	COG1506	peptidase
CWD84_RS04575	COG0823	Involved in the tonB-independent uptake of proteins
CWD84_RS04580	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CWD84_RS04585	COG4837	Protein of unknown function (DUF1462)
CWD84_RS04590	COG1252	NADH dehydrogenase
CWD84_RS04600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CWD84_RS04610	COG0316	Belongs to the HesB IscA family
CWD84_RS04615	COG4974	Belongs to the 'phage' integrase family
CWD84_RS04625	COG0582	viral genome integration into host DNA
CWD84_RS04720	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CWD84_RS04745	COG1131	(ABC) transporter
CWD84_RS04775	COG1252	NADH dehydrogenase
CWD84_RS04790	COG3584	3D domain protein
CWD84_RS04795	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CWD84_RS04805	COG2056	Na+-H+ antiporter family
CWD84_RS04810	COG1268	BioY protein
CWD84_RS04815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWD84_RS04820	COG2819	hydrolase of the alpha beta superfamily
CWD84_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS04830	COG1169	isochorismate synthase
CWD84_RS04835	COG1021	2,3-dihydroxybenzoate-AMP ligase
CWD84_RS04840	COG1535	isochorismatase
CWD84_RS04840	COG3433	isochorismatase activity
CWD84_RS04845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS04850	COG3251	PFAM MbtH domain protein
CWD84_RS04855	COG5634	Uncharacterized conserved protein (DUF2278)
CWD84_RS04860	COG0686	Belongs to the AlaDH PNT family
CWD84_RS04865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CWD84_RS04865	COG2508	Transcriptional regulator
CWD84_RS04870	COG4842	Belongs to the WXG100 family
CWD84_RS04875	COG5417	Belongs to the EsaB family
CWD84_RS04880	COG4499	WXG100 protein secretion system (Wss), protein YukC
CWD84_RS04885	COG0433	COG0433 Predicted ATPase
CWD84_RS04885	COG1674	ftsk spoiiie
CWD84_RS04890	COG1511	domain protein
CWD84_RS04900	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS04905	COG1418	mRNA catabolic process
CWD84_RS04915	COG0628	permease
CWD84_RS04930	COG5506	Protein of unknown function (DUF1694)
CWD84_RS04935	COG1335	isochorismatase
CWD84_RS04940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWD84_RS04945	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CWD84_RS04965	COG0142	geranyltranstransferase activity
CWD84_RS04975	COG4585	Histidine kinase
CWD84_RS04980	COG2197	response regulator
CWD84_RS04985	COG2050	protein possibly involved in aromatic compounds catabolism
CWD84_RS04990	COG1320	monovalent cation:proton antiporter activity
CWD84_RS04995	COG2212	antiporter activity
CWD84_RS05000	COG1863	multisubunit Na H antiporter MnhE subunit
CWD84_RS05005	COG0651	ATP synthesis coupled electron transport
CWD84_RS05010	COG1006	Multisubunit Na H antiporter MnhC subunit
CWD84_RS05015	COG2111	Na H antiporter
CWD84_RS05020	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CWD84_RS05020	COG2111	Na H antiporter
CWD84_RS05030	COG1079	Belongs to the binding-protein-dependent transport system permease family
CWD84_RS05035	COG4603	Belongs to the binding-protein-dependent transport system permease family
CWD84_RS05040	COG3845	ABC transporter
CWD84_RS05045	COG1744	ABC transporter substrate-binding protein PnrA-like
CWD84_RS05050	COG4565	transcriptional regulatory protein
CWD84_RS05055	COG3290	protein histidine kinase activity
CWD84_RS05065	COG3011	Protein conserved in bacteria
CWD84_RS05070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWD84_RS05075	COG2814	Major facilitator Superfamily
CWD84_RS05080	COG5018	Exonuclease
CWD84_RS05090	COG2205	protein histidine kinase activity
CWD84_RS05095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWD84_RS05105	COG2267	carboxylic ester hydrolase activity
CWD84_RS05110	COG1522	sequence-specific DNA binding
CWD84_RS05115	COG0436	Aminotransferase
CWD84_RS05120	COG1098	S1 RNA binding domain
CWD84_RS05125	COG2155	Conserved Protein
CWD84_RS05130	COG1979	alcohol dehydrogenase
CWD84_RS05135	COG1979	alcohol dehydrogenase
CWD84_RS05140	COG1335	isochorismatase
CWD84_RS05165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWD84_RS05180	COG2738	Putative neutral zinc metallopeptidase
CWD84_RS05185	COG1253	flavin adenine dinucleotide binding
CWD84_RS05190	COG0366	Alpha amylase catalytic
CWD84_RS05195	COG0432	Pfam Uncharacterised protein family UPF0047
CWD84_RS05200	COG2070	2-Nitropropane dioxygenase
CWD84_RS05215	COG0840	transmembrane signaling receptor activity
CWD84_RS05220	COG0840	transmembrane signaling receptor activity
CWD84_RS05225	COG0840	transmembrane signaling receptor activity
CWD84_RS05230	COG0840	transmembrane signaling receptor activity
CWD84_RS05235	COG0693	protein deglycase activity
CWD84_RS05240	COG0673	inositol 2-dehydrogenase activity
CWD84_RS05245	COG0628	permease
CWD84_RS05270	COG0457	Tetratricopeptide repeat
CWD84_RS05285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWD84_RS05285	COG1017	nitric oxide dioxygenase activity
CWD84_RS05290	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS05295	COG0569	domain protein
CWD84_RS05305	COG1510	regulation of RNA biosynthetic process
CWD84_RS05310	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS05315	COG1454	alcohol dehydrogenase
CWD84_RS05325	COG2318	DinB family
CWD84_RS05330	COG1585	Membrane protein implicated in regulation of membrane protease activity
CWD84_RS05335	COG2268	Band 7 protein
CWD84_RS05340	COG3859	Proton-coupled thiamine transporter YuaJ
CWD84_RS05465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CWD84_RS05470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWD84_RS05475	COG1169	isochorismate synthase
CWD84_RS05485	COG0596	Alpha beta hydrolase
CWD84_RS05490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWD84_RS05500	COG4948	Mandelate Racemase Muconate Lactonizing
CWD84_RS05515	COG1294	oxidase, subunit
CWD84_RS05520	COG1271	oxidase subunit
CWD84_RS05530	COG0288	reversible hydration of carbon dioxide
CWD84_RS05555	COG0783	Belongs to the Dps family
CWD84_RS05560	COG4824	toxin secretion phage lysis holin
CWD84_RS05565	COG0494	nUDIX hydrolase
CWD84_RS05570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWD84_RS05575	COG1116	anion transmembrane transporter activity
CWD84_RS05580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWD84_RS05585	COG1506	peptidase
CWD84_RS05605	COG0367	asparagine synthase
CWD84_RS05610	COG1113	amino acid transport
CWD84_RS05615	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CWD84_RS05620	COG2267	carboxylic ester hydrolase activity
CWD84_RS05640	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CWD84_RS05645	COG1242	4 iron, 4 sulfur cluster binding
CWD84_RS05650	COG0477	Major facilitator Superfamily
CWD84_RS05655	COG0640	Transcriptional regulator
CWD84_RS05665	COG1725	Transcriptional regulator
CWD84_RS05670	COG1131	(ABC) transporter
CWD84_RS05690	COG1136	(ABC) transporter
CWD84_RS05695	COG0577	efflux transmembrane transporter activity
CWD84_RS05700	COG0745	RESPONSE REGULATOR receiver
CWD84_RS05705	COG2205	protein histidine kinase activity
CWD84_RS05710	COG1136	(ABC) transporter
CWD84_RS05715	COG0577	efflux transmembrane transporter activity
CWD84_RS05720	COG5522	Integral membrane protein (intg_mem_TP0381)
CWD84_RS05725	COG2814	Major facilitator Superfamily
CWD84_RS05730	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS05730	COG2202	Pas domain
CWD84_RS05745	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWD84_RS05765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWD84_RS05770	COG2081	HI0933 family
CWD84_RS05775	COG2244	polysaccharide biosynthetic process
CWD84_RS05780	COG1187	pseudouridine synthase activity
CWD84_RS05785	COG1349	DNA-binding transcription factor activity
CWD84_RS05790	COG1131	(ABC) transporter
CWD84_RS05795	COG4473	ABC transporter
CWD84_RS05800	COG2252	PERMEase
CWD84_RS05805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWD84_RS05810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWD84_RS05815	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CWD84_RS05825	COG1597	lipid kinase activity
CWD84_RS05830	COG0510	thiamine kinase activity
CWD84_RS05845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWD84_RS05850	COG0281	malic enzyme
CWD84_RS05855	COG5584	Small secreted protein
CWD84_RS05860	COG1363	Peptidase, m42
CWD84_RS05865	COG2323	membrane
CWD84_RS05870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWD84_RS05880	COG2323	membrane
CWD84_RS05895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWD84_RS05930	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS05975	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS05985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWD84_RS05990	COG1674	ftsk spoiiie
CWD84_RS06000	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CWD84_RS06005	COG4980	gas vesicle protein
CWD84_RS06010	COG3118	belongs to the thioredoxin family
CWD84_RS06015	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CWD84_RS06015	COG1605	Chorismate mutase
CWD84_RS06020	COG1609	Transcriptional regulator
CWD84_RS06025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CWD84_RS06030	COG1360	Flagellar Motor Protein
CWD84_RS06035	COG0123	including yeast histone deacetylase and acetoin utilization protein
CWD84_RS06040	COG0517	IMP dehydrogenase activity
CWD84_RS06045	COG0454	-acetyltransferase
CWD84_RS06050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWD84_RS06075	COG1378	Sugar-specific transcriptional regulator TrmB
CWD84_RS06080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWD84_RS06095	COG0693	protein deglycase activity
CWD84_RS06105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWD84_RS06105	COG1017	nitric oxide dioxygenase activity
CWD84_RS06140	COG4282	regulation of fungal-type cell wall biogenesis
CWD84_RS06145	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS06160	COG2203	Gaf domain
CWD84_RS06160	COG2199	diguanylate cyclase activity
CWD84_RS06165	COG1956	GAF domain-containing protein
CWD84_RS06170	COG1309	transcriptional regulator
CWD84_RS06175	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CWD84_RS06185	COG1114	Component of the transport system for branched-chain amino acids
CWD84_RS06190	COG1104	cysteine desulfurase activity
CWD84_RS06205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWD84_RS06210	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CWD84_RS06215	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWD84_RS06220	COG0616	signal peptide processing
CWD84_RS06225	COG1714	RDD family
CWD84_RS06235	COG3874	Sporulation protein YtfJ
CWD84_RS06240	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CWD84_RS06245	COG0827	DNA restriction-modification system
CWD84_RS06255	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWD84_RS06270	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS06280	COG4109	DRTGG domain
CWD84_RS06290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWD84_RS06310	COG0587	DNA-directed DNA polymerase activity
CWD84_RS06315	COG0281	malic enzyme
CWD84_RS06335	COG0469	pyruvate kinase activity
CWD84_RS06340	COG3030	protein affecting phage T7 exclusion by the F plasmid
CWD84_RS06345	COG0628	permease
CWD84_RS06355	COG0372	Belongs to the citrate synthase family
CWD84_RS06360	COG0538	isocitrate dehydrogenase activity
CWD84_RS06370	COG0745	RESPONSE REGULATOR receiver
CWD84_RS06375	COG5002	protein histidine kinase activity
CWD84_RS06380	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWD84_RS06380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWD84_RS06385	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWD84_RS06390	COG1971	Probably functions as a manganese efflux pump
CWD84_RS06395	COG0237	dephospho-CoA kinase activity
CWD84_RS06400	COG0656	L-ascorbic acid biosynthetic process
CWD84_RS06405	COG2814	Major facilitator Superfamily
CWD84_RS06410	COG1733	regulation of RNA biosynthetic process
CWD84_RS06415	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWD84_RS06430	COG3611	Membrane attachment protein
CWD84_RS06435	COG1484	DNA-dependent DNA replication
CWD84_RS06440	COG0398	Pfam SNARE associated Golgi protein
CWD84_RS06455	COG1011	Hydrolase
CWD84_RS06460	COG3275	phosphorelay sensor kinase activity
CWD84_RS06465	COG3279	Response regulator of the LytR AlgR family
CWD84_RS06470	COG1380	Effector of murein hydrolase LrgA
CWD84_RS06475	COG1346	cytolysis
CWD84_RS06480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWD84_RS06495	COG3326	Membrane
CWD84_RS06505	COG1363	Peptidase, m42
CWD84_RS06515	COG2160	L-arabinose isomerase activity
CWD84_RS06520	COG1069	ribulokinase activity
CWD84_RS06525	COG0235	Class ii aldolase
CWD84_RS06530	COG0647	UMP catabolic process
CWD84_RS06540	COG1653	transport
CWD84_RS06545	COG1175	transmembrane transport
CWD84_RS06550	COG0395	ABC-type sugar transport system, permease component
CWD84_RS06555	COG3534	alpha-L-arabinofuranosidase
CWD84_RS06560	COG1966	Carbon starvation protein
CWD84_RS06565	COG0247	lactate metabolic process
CWD84_RS06570	COG0277	FAD linked oxidase domain protein
CWD84_RS06575	COG3835	regulator
CWD84_RS06585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWD84_RS06590	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CWD84_RS06595	COG0072	phenylalanine-tRNA ligase activity
CWD84_RS06595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWD84_RS06610	COG1286	toxin biosynthetic process
CWD84_RS06615	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CWD84_RS06615	COG1796	DNA polymerase
CWD84_RS06625	COG3766	membrane
CWD84_RS06635	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS06640	COG1309	transcriptional regulator
CWD84_RS06645	COG1024	Enoyl-CoA hydratase
CWD84_RS06650	COG2086	electron transfer activity
CWD84_RS06655	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CWD84_RS06660	COG3534	alpha-L-arabinofuranosidase
CWD84_RS06665	COG3118	belongs to the thioredoxin family
CWD84_RS06675	COG0527	aspartate kinase activity
CWD84_RS06680	COG1719	4-vinyl reductase, 4VR
CWD84_RS06685	COG2009	succinate dehydrogenase
CWD84_RS06690	COG1053	succinate dehydrogenase
CWD84_RS06695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWD84_RS06700	COG0824	Thioesterase
CWD84_RS06705	COG2197	response regulator
CWD84_RS06710	COG1846	Transcriptional regulator
CWD84_RS06720	COG5401	PFAM Sporulation and spore germination
CWD84_RS06730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CWD84_RS06735	COG0622	Phosphoesterase
CWD84_RS06750	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CWD84_RS06790	COG0028	Belongs to the TPP enzyme family
CWD84_RS06795	COG0440	acetolactate synthase activity
CWD84_RS06810	COG0473	3-isopropylmalate dehydrogenase activity
CWD84_RS06825	COG0457	Tetratricopeptide repeat
CWD84_RS06825	COG1477	protein flavinylation
CWD84_RS06840	COG0470	DNA polymerase III
CWD84_RS06840	COG1067	ATP-dependent peptidase activity
CWD84_RS06845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWD84_RS06865	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWD84_RS06875	COG1587	Uroporphyrinogen-III synthase
CWD84_RS06880	COG0113	porphobilinogen synthase activity
CWD84_RS06890	COG1388	LysM domain
CWD84_RS06895	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CWD84_RS06905	COG0525	valine-tRNA ligase activity
CWD84_RS06910	COG0285	dihydrofolate synthase activity
CWD84_RS06915	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CWD84_RS06935	COG1077	Cell shape determining protein MreB Mrl
CWD84_RS06945	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CWD84_RS06955	COG2894	cell division
CWD84_RS06960	COG0739	heme binding
CWD84_RS06965	COG1994	Peptidase M50
CWD84_RS06975	COG2868	ribosomal protein
CWD84_RS06980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWD84_RS06985	COG3290	protein histidine kinase activity
CWD84_RS07000	COG0077	Prephenate dehydratase
CWD84_RS07005	COG1827	regulation of RNA biosynthetic process
CWD84_RS07010	COG1104	cysteine desulfurase activity
CWD84_RS07015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CWD84_RS07020	COG0157	Belongs to the NadC ModD family
CWD84_RS07030	COG1388	LysM domain
CWD84_RS07070	COG1862	Preprotein translocase
CWD84_RS07080	COG2323	membrane
CWD84_RS07085	COG2244	polysaccharide biosynthetic process
CWD84_RS07095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWD84_RS07095	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWD84_RS07100	COG0490	domain, Protein
CWD84_RS07105	COG5416	Lipopolysaccharide assembly protein A domain
CWD84_RS07110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWD84_RS07110	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWD84_RS07120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWD84_RS07125	COG1490	D-aminoacyl-tRNA deacylase activity
CWD84_RS07130	COG3103	Sh3 type 3 domain protein
CWD84_RS07130	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS07130	COG4991	sh3 domain protein
CWD84_RS07150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CWD84_RS07155	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWD84_RS07160	COG1959	2 iron, 2 sulfur cluster binding
CWD84_RS07165	COG1104	cysteine desulfurase activity
CWD84_RS07175	COG0457	Tetratricopeptide repeat
CWD84_RS07180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWD84_RS07185	COG3881	PFAM PRC-barrel domain
CWD84_RS07200	COG0765	amino acid transport
CWD84_RS07205	COG0765	amino acid transport
CWD84_RS07210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS07215	COG1126	abc transporter atp-binding protein
CWD84_RS07220	COG0628	permease
CWD84_RS07230	COG4472	Bacterial protein of unknown function (DUF965)
CWD84_RS07245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWD84_RS07250	COG4122	O-methyltransferase activity
CWD84_RS07255	COG0826	peptidase U32
CWD84_RS07260	COG0826	peptidase U32
CWD84_RS07280	COG1396	sequence-specific DNA binding
CWD84_RS07370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWD84_RS07375	COG0582	viral genome integration into host DNA
CWD84_RS07380	COG1674	ftsk spoiiie
CWD84_RS07380	COG4980	gas vesicle protein
CWD84_RS07480	COG3953	SLT domain
CWD84_RS07480	COG5280	Phage tail tape measure protein TP901
CWD84_RS07490	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS07495	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS07515	COG4824	toxin secretion phage lysis holin
CWD84_RS07520	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS07520	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS07560	COG1396	sequence-specific DNA binding
CWD84_RS07650	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWD84_RS07655	COG0582	viral genome integration into host DNA
CWD84_RS07660	COG4980	gas vesicle protein
CWD84_RS07660	COG1674	ftsk spoiiie
CWD84_RS07760	COG5280	Phage tail tape measure protein TP901
CWD84_RS07760	COG3953	SLT domain
CWD84_RS07770	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS07775	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS07795	COG4824	toxin secretion phage lysis holin
CWD84_RS07800	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS07800	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS07840	COG1396	sequence-specific DNA binding
CWD84_RS07930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWD84_RS07935	COG0582	viral genome integration into host DNA
CWD84_RS07940	COG1674	ftsk spoiiie
CWD84_RS07940	COG4980	gas vesicle protein
CWD84_RS08040	COG5280	Phage tail tape measure protein TP901
CWD84_RS08040	COG3953	SLT domain
CWD84_RS08050	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS08055	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS08075	COG4824	toxin secretion phage lysis holin
CWD84_RS08080	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS08080	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS08120	COG1396	sequence-specific DNA binding
CWD84_RS08210	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWD84_RS08215	COG0582	viral genome integration into host DNA
CWD84_RS08220	COG1674	ftsk spoiiie
CWD84_RS08220	COG4980	gas vesicle protein
CWD84_RS08320	COG5280	Phage tail tape measure protein TP901
CWD84_RS08320	COG3953	SLT domain
CWD84_RS08330	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS08335	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS08355	COG4824	toxin secretion phage lysis holin
CWD84_RS08360	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS08360	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS08400	COG1396	sequence-specific DNA binding
CWD84_RS08490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWD84_RS08495	COG0582	viral genome integration into host DNA
CWD84_RS08500	COG1674	ftsk spoiiie
CWD84_RS08500	COG4980	gas vesicle protein
CWD84_RS08600	COG5280	Phage tail tape measure protein TP901
CWD84_RS08600	COG3953	SLT domain
CWD84_RS08610	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS08615	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS08635	COG4824	toxin secretion phage lysis holin
CWD84_RS08640	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS08640	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS08675	COG0768	penicillin binding
CWD84_RS08700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWD84_RS08705	COG0626	cystathionine gamma-synthase activity
CWD84_RS08715	COG2427	Protein of unknown function (DUF1641)
CWD84_RS08720	COG3383	formate dehydrogenase (NAD+) activity
CWD84_RS08725	COG5609	conserved protein (DUF2294)
CWD84_RS08730	COG2116	formate transmembrane transporter activity
CWD84_RS08745	COG2226	methyltransferase
CWD84_RS08750	COG1309	transcriptional regulator
CWD84_RS08755	COG2124	cytochrome p450
CWD84_RS08755	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CWD84_RS08760	COG2814	Major facilitator Superfamily
CWD84_RS08765	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWD84_RS08780	COG0561	phosphatase activity
CWD84_RS08795	COG2318	DinB family
CWD84_RS08805	COG2814	Major facilitator Superfamily
CWD84_RS08815	COG0563	adenylate kinase activity
CWD84_RS08825	COG2207	Transcriptional regulator
CWD84_RS08825	COG3708	Transcriptional regulator
CWD84_RS08880	COG5484	DNA packaging
CWD84_RS08890	COG0656	L-ascorbic acid biosynthetic process
CWD84_RS08910	COG1733	regulation of RNA biosynthetic process
CWD84_RS08930	COG0398	Pfam SNARE associated Golgi protein
CWD84_RS08945	COG2755	lipolytic protein G-D-S-L family
CWD84_RS08955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CWD84_RS08960	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWD84_RS08965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWD84_RS08970	COG1534	Rna-binding protein
CWD84_RS08980	COG1713	HD superfamily hydrolase involved in NAD metabolism
CWD84_RS08985	COG0799	negative regulation of ribosome biogenesis
CWD84_RS08990	COG2226	methyltransferase
CWD84_RS08995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWD84_RS09000	COG1596	polysaccharide export
CWD84_RS09000	COG1555	photosystem II stabilization
CWD84_RS09005	COG2131	deaminase
CWD84_RS09010	COG2333	competence protein COMEC
CWD84_RS09010	COG0658	competence protein
CWD84_RS09020	COG1466	dna polymerase III delta subunit
CWD84_RS09035	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS09050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWD84_RS09080	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWD84_RS09085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWD84_RS09090	COG1283	sodium-dependent phosphate transmembrane transporter activity
CWD84_RS09100	COG1610	YqeY-like protein
CWD84_RS09105	COG1030	water channel activity
CWD84_RS09110	COG4864	UPF0365 protein
CWD84_RS09125	COG0561	phosphatase activity
CWD84_RS09130	COG1702	phosphate starvation-inducible protein PhoH
CWD84_RS09135	COG1480	7TM receptor with intracellular HD hydrolase
CWD84_RS09145	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CWD84_RS09150	COG0295	cytidine deaminase activity
CWD84_RS09155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWD84_RS09175	COG0751	glycine-tRNA ligase activity
CWD84_RS09180	COG0517	IMP dehydrogenase activity
CWD84_RS09195	COG0358	DNA primase activity
CWD84_RS09200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWD84_RS09205	COG2010	Cytochrome c
CWD84_RS09210	COG2384	SAM-dependent methyltransferase
CWD84_RS09215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWD84_RS09230	COG0513	Belongs to the DEAD box helicase family
CWD84_RS09245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS09250	COG0735	belongs to the Fur family
CWD84_RS09255	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
CWD84_RS09260	COG4709	membrane
CWD84_RS09270	COG1388	LysM domain
CWD84_RS09275	COG5521	maltodextrose utilization protein MalA
CWD84_RS09280	COG2839	Protein conserved in bacteria
CWD84_RS09285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWD84_RS09290	COG0477	Major facilitator Superfamily
CWD84_RS09295	COG0768	penicillin binding
CWD84_RS09300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWD84_RS09305	COG0573	inorganic phosphate transmembrane transporter activity
CWD84_RS09310	COG0581	inorganic phosphate transmembrane transporter activity
CWD84_RS09315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWD84_RS09320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWD84_RS09325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWD84_RS09340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWD84_RS09350	COG1757	Na H antiporter
CWD84_RS09355	COG4483	Protein conserved in bacteria
CWD84_RS09360	COG1940	carbohydrate kinase activity
CWD84_RS09365	COG2866	Carboxypeptidase
CWD84_RS09375	COG0011	TIGRFAM Protein of
CWD84_RS09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWD84_RS09395	COG1393	Belongs to the ArsC family
CWD84_RS09405	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS09410	COG1253	flavin adenine dinucleotide binding
CWD84_RS09415	COG0598	Magnesium transport protein CorA
CWD84_RS09420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWD84_RS09425	COG1459	type II secretion system
CWD84_RS09430	COG4537	Required for transformation and DNA binding
CWD84_RS09435	COG4970	Tfp pilus assembly protein FimT
CWD84_RS09445	COG4940	Competence protein ComGF
CWD84_RS09470	COG0681	Belongs to the peptidase S26 family
CWD84_RS09480	COG1396	sequence-specific DNA binding
CWD84_RS09495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWD84_RS09515	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWD84_RS09530	COG1752	Esterase of the alpha-beta hydrolase superfamily
CWD84_RS09540	COG3872	metal-dependent enzyme
CWD84_RS09550	COG0006	proline dipeptidase activity
CWD84_RS09565	COG3854	ATPases associated with a variety of cellular activities
CWD84_RS09605	COG0511	ligase activity, forming carbon-carbon bonds
CWD84_RS09610	COG0439	Biotin carboxylase
CWD84_RS09615	COG1302	Protein conserved in bacteria
CWD84_RS09630	COG1570	exodeoxyribonuclease VII activity
CWD84_RS09640	COG0142	geranyltranstransferase activity
CWD84_RS09650	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CWD84_RS09660	COG0497	DNA recombination
CWD84_RS09665	COG0750	zinc metalloprotease
CWD84_RS09670	COG0745	RESPONSE REGULATOR receiver
CWD84_RS09680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWD84_RS09695	COG1902	pentaerythritol trinitrate reductase activity
CWD84_RS09715	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS09720	COG0584	glycerophosphoryl diester phosphodiesterase
CWD84_RS09725	COG0183	Belongs to the thiolase family
CWD84_RS09730	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWD84_RS09735	COG1960	acyl-CoA dehydrogenase activity
CWD84_RS09740	COG0372	Belongs to the citrate synthase family
CWD84_RS09745	COG2079	MmgE PrpD family protein
CWD84_RS09750	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CWD84_RS09760	COG3829	transcription factor binding
CWD84_RS09760	COG3290	protein histidine kinase activity
CWD84_RS09765	COG0280	phosphate acetyltransferase
CWD84_RS09770	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWD84_RS09775	COG3426	butyrate kinase activity
CWD84_RS09780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWD84_RS09785	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWD84_RS09790	COG0022	dehydrogenase e1 component
CWD84_RS09795	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWD84_RS09800	COG1597	lipid kinase activity
CWD84_RS09810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS09815	COG0765	amino acid transport
CWD84_RS09820	COG1126	abc transporter atp-binding protein
CWD84_RS09825	COG4129	membrane
CWD84_RS09830	COG1376	ErfK ybiS ycfS ynhG family protein
CWD84_RS09835	COG0346	lactoylglutathione lyase activity
CWD84_RS09840	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWD84_RS09845	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWD84_RS09850	COG0706	membrane insertase activity
CWD84_RS09865	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CWD84_RS09870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWD84_RS09885	COG0596	Alpha beta hydrolase
CWD84_RS09900	COG0250	Participates in transcription elongation, termination and antitermination
CWD84_RS09910	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWD84_RS09910	COG2070	2-Nitropropane dioxygenase
CWD84_RS09925	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09935	COG3321	synthase
CWD84_RS09935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS09935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS09940	COG0300	oxidoreductase activity
CWD84_RS09940	COG3321	synthase
CWD84_RS09940	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS09940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09945	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09945	COG3321	synthase
CWD84_RS09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS09945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS09950	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09950	COG3321	synthase
CWD84_RS09950	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS09950	COG0300	oxidoreductase activity
CWD84_RS09955	COG0300	oxidoreductase activity
CWD84_RS09955	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS09955	COG3321	synthase
CWD84_RS09955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09960	COG3321	synthase
CWD84_RS09960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS09960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS09965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS09965	COG3321	synthase
CWD84_RS09965	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS09965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS09970	COG2124	cytochrome p450
CWD84_RS09975	COG3425	synthase
CWD84_RS09980	COG1024	Enoyl-CoA hydratase
CWD84_RS09985	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWD84_RS09990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWD84_RS09995	COG0300	oxidoreductase activity
CWD84_RS10000	COG3048	D-serine ammonia-lyase activity
CWD84_RS10010	COG0346	lactoylglutathione lyase activity
CWD84_RS10020	COG0628	permease
CWD84_RS10035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWD84_RS10040	COG0456	acetyltransferase
CWD84_RS10045	COG2329	Antibiotic biosynthesis monooxygenase
CWD84_RS10050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CWD84_RS10050	COG0456	acetyltransferase
CWD84_RS10055	COG4918	Iron-sulphur cluster biosynthesis
CWD84_RS10065	COG1073	alpha beta
CWD84_RS10075	COG0667	Aldo Keto reductase
CWD84_RS10085	COG0494	nUDIX hydrolase
CWD84_RS10090	COG1379	DNA repair
CWD84_RS10095	COG1396	sequence-specific DNA binding
CWD84_RS10100	COG0252	asparaginase activity
CWD84_RS10105	COG1027	Aspartate ammonia-lyase
CWD84_RS10110	COG1757	Na H antiporter
CWD84_RS10115	COG0281	malic enzyme
CWD84_RS10130	COG1300	Membrane
CWD84_RS10135	COG0735	belongs to the Fur family
CWD84_RS10145	COG4974	Belongs to the 'phage' integrase family
CWD84_RS10150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CWD84_RS10155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CWD84_RS10160	COG1686	Belongs to the peptidase S11 family
CWD84_RS10165	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS10175	COG1191	sigma factor activity
CWD84_RS10195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWD84_RS10210	COG0697	spore germination
CWD84_RS10215	COG0019	diaminopimelate decarboxylase activity
CWD84_RS10220	COG4086	secreted protein
CWD84_RS10225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CWD84_RS10235	COG0681	Belongs to the peptidase S26 family
CWD84_RS10245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWD84_RS10245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWD84_RS10250	COG0307	riboflavin synthase, alpha
CWD84_RS10265	COG0456	acetyltransferase
CWD84_RS10275	COG1547	Domain of unknown function (DUF309)
CWD84_RS10300	COG1686	Belongs to the peptidase S11 family
CWD84_RS10305	COG2715	membrane protein required for spore maturation
CWD84_RS10310	COG0700	Nucleoside recognition
CWD84_RS10315	COG1187	pseudouridine synthase activity
CWD84_RS10320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS10325	COG1333	cytochrome c biogenesis protein
CWD84_RS10330	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWD84_RS10335	COG0745	RESPONSE REGULATOR receiver
CWD84_RS10340	COG5002	protein histidine kinase activity
CWD84_RS10345	COG1595	DNA-templated transcription, initiation
CWD84_RS10355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWD84_RS10360	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CWD84_RS10365	COG1141	Ferredoxin
CWD84_RS10370	COG4955	Helix-turn-helix domain
CWD84_RS10375	COG0514	ATP-dependent DNA helicase (RecQ)
CWD84_RS10380	COG1266	CAAX protease self-immunity
CWD84_RS10385	COG1388	LysM domain
CWD84_RS10395	COG1408	metallophosphoesterase
CWD84_RS10400	COG4862	establishment of competence for transformation
CWD84_RS10405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWD84_RS10410	COG0492	ferredoxin-NADP+ reductase activity
CWD84_RS10415	COG2339	peptidase activity
CWD84_RS10420	COG3773	Cell wall hydrolase
CWD84_RS10420	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS10425	COG2959	enzyme of heme biosynthesis
CWD84_RS10430	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CWD84_RS10440	COG0539	negative regulation of cytoplasmic translation
CWD84_RS10480	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CWD84_RS10485	COG0776	regulation of translation
CWD84_RS10500	COG0142	geranyltranstransferase activity
CWD84_RS10510	COG0142	geranyltranstransferase activity
CWD84_RS10515	COG0105	UTP biosynthetic process
CWD84_RS10520	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CWD84_RS10535	COG4401	Chorismate mutase type I
CWD84_RS10540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWD84_RS10575	COG0287	Prephenate dehydrogenase
CWD84_RS10585	COG0457	Tetratricopeptide repeat
CWD84_RS10600	COG0723	plastoquinol--plastocyanin reductase activity
CWD84_RS10605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWD84_RS10610	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWD84_RS10610	COG2010	Cytochrome c
CWD84_RS10615	COG4347	Protein of unknown function (DUF1405)
CWD84_RS10625	COG2140	Oxalate decarboxylase
CWD84_RS10630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS10635	COG1694	Mazg nucleotide pyrophosphohydrolase
CWD84_RS10650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWD84_RS10655	COG0438	transferase activity, transferring glycosyl groups
CWD84_RS10665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CWD84_RS10665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CWD84_RS10685	COG1199	ATP-dependent helicase activity
CWD84_RS10685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWD84_RS10695	COG5353	protein conserved in bacteria
CWD84_RS10700	COG0436	Aminotransferase
CWD84_RS10710	COG3935	DnaD domain protein
CWD84_RS10715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWD84_RS10725	COG4499	WXG100 protein secretion system (Wss), protein YukC
CWD84_RS10725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWD84_RS10765	COG0071	Belongs to the small heat shock protein (HSP20) family
CWD84_RS10770	COG2190	(PTS) system
CWD84_RS10775	COG1205	dead DEAH box helicase
CWD84_RS10775	COG1111	helicase
CWD84_RS10780	COG3359	exonuclease
CWD84_RS10805	COG0116	Belongs to the methyltransferase superfamily
CWD84_RS10820	COG1199	ATP-dependent helicase activity
CWD84_RS10825	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CWD84_RS10835	COG2233	PERMEase
CWD84_RS10845	COG1335	isochorismatase
CWD84_RS10870	COG3424	synthase
CWD84_RS10875	COG1755	Isoprenylcysteine carboxyl methyltransferase
CWD84_RS10885	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CWD84_RS10900	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWD84_RS10910	COG0328	RNA-DNA hybrid ribonuclease activity
CWD84_RS10915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CWD84_RS10920	COG0328	RNA-DNA hybrid ribonuclease activity
CWD84_RS10940	COG1278	Cold shock
CWD84_RS10945	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWD84_RS10955	COG0386	Belongs to the glutathione peroxidase family
CWD84_RS10965	COG1413	lyase activity
CWD84_RS10980	COG2521	methyltransferase
CWD84_RS10980	COG2136	Putative SAM-dependent methyltransferase
CWD84_RS10995	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWD84_RS11000	COG0204	Acyl-transferase
CWD84_RS11005	COG1272	protein, Hemolysin III
CWD84_RS11010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CWD84_RS11015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWD84_RS11025	COG1999	signal sequence binding
CWD84_RS11030	COG2755	lipolytic protein G-D-S-L family
CWD84_RS11035	COG4698	Protein conserved in bacteria
CWD84_RS11040	COG1846	Transcriptional regulator
CWD84_RS11055	COG1086	Polysaccharide biosynthesis protein
CWD84_RS11060	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWD84_RS11085	COG4282	regulation of fungal-type cell wall biogenesis
CWD84_RS11090	COG5444	nuclease activity
CWD84_RS11120	COG3391	amine dehydrogenase activity
CWD84_RS11130	COG0457	Tetratricopeptide repeat
CWD84_RS11170	COG0477	Major facilitator Superfamily
CWD84_RS11180	COG1086	Polysaccharide biosynthesis protein
CWD84_RS11190	COG4641	Protein conserved in bacteria
CWD84_RS11205	COG0463	Glycosyl transferase, family 2
CWD84_RS11210	COG0456	acetyltransferase
CWD84_RS11220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CWD84_RS11225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWD84_RS11230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CWD84_RS11235	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWD84_RS11240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWD84_RS11245	COG0456	acetyltransferase
CWD84_RS11250	COG1509	lysine 2,3-aminomutase activity
CWD84_RS11275	COG0671	phosphoesterase, PA-phosphatase related
CWD84_RS11295	COG1876	peptidase activity
CWD84_RS11305	COG2226	methyltransferase
CWD84_RS11310	COG0793	Belongs to the peptidase S41A family
CWD84_RS11310	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS11315	COG2188	Transcriptional regulator
CWD84_RS11320	COG2723	6-phospho-beta-galactosidase activity
CWD84_RS11330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWD84_RS11340	COG0346	lactoylglutathione lyase activity
CWD84_RS11345	COG0400	carboxylic ester hydrolase activity
CWD84_RS11350	COG0778	Nitroreductase
CWD84_RS11355	COG1733	regulation of RNA biosynthetic process
CWD84_RS11380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWD84_RS11385	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWD84_RS11390	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS11395	COG0534	Mate efflux family protein
CWD84_RS11400	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CWD84_RS11405	COG1819	glycosyl
CWD84_RS11410	COG1388	LysM domain
CWD84_RS11410	COG0791	NLP P60 protein
CWD84_RS11415	COG2032	superoxide dismutase activity
CWD84_RS11420	COG0714	Associated with various cellular activities
CWD84_RS11425	COG4548	von Willebrand factor, type A
CWD84_RS11435	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWD84_RS11440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWD84_RS11445	COG0385	Bile acid
CWD84_RS11450	COG0733	neurotransmitter:sodium symporter activity
CWD84_RS11455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWD84_RS11460	COG1657	PFAM Prenyltransferase squalene oxidase
CWD84_RS11465	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS11495	COG0071	Belongs to the small heat shock protein (HSP20) family
CWD84_RS11510	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWD84_RS11515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CWD84_RS11525	COG0514	ATP-dependent DNA helicase (RecQ)
CWD84_RS11530	COG3584	3D domain protein
CWD84_RS11530	COG1388	LysM domain
CWD84_RS11540	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWD84_RS11555	COG2322	membrane
CWD84_RS11560	COG0741	lytic transglycosylase activity
CWD84_RS11565	COG0640	Transcriptional regulator
CWD84_RS11575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWD84_RS11580	COG1309	transcriptional regulator
CWD84_RS11585	COG2207	Transcriptional regulator
CWD84_RS11585	COG0662	Cupin 2, conserved barrel domain protein
CWD84_RS11590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWD84_RS11595	COG5444	nuclease activity
CWD84_RS11625	COG0243	molybdopterin cofactor binding
CWD84_RS11630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWD84_RS11640	COG2814	Major facilitator Superfamily
CWD84_RS11650	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CWD84_RS11655	COG0300	oxidoreductase activity
CWD84_RS11670	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWD84_RS11675	COG0583	DNA-binding transcription factor activity
CWD84_RS11680	COG0067	glutamate synthase
CWD84_RS11680	COG0069	glutamate synthase activity
CWD84_RS11680	COG0070	glutamate synthase
CWD84_RS11685	COG0493	'glutamate synthase
CWD84_RS11695	COG0604	alcohol dehydrogenase
CWD84_RS11705	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWD84_RS11710	COG0640	Transcriptional regulator
CWD84_RS11715	COG2814	Major facilitator Superfamily
CWD84_RS11720	COG0405	Gamma-glutamyltransferase
CWD84_RS11725	COG0166	Belongs to the GPI family
CWD84_RS11730	COG0582	viral genome integration into host DNA
CWD84_RS11745	COG0534	Mate efflux family protein
CWD84_RS11750	COG2017	converts alpha-aldose to the beta-anomer
CWD84_RS11755	COG2027	D-alanyl-D-alanine carboxypeptidase
CWD84_RS11765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS11770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS11775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS11780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS11785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS11785	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CWD84_RS11795	COG1649	PFAM Uncharacterised BCR, COG1649
CWD84_RS11800	COG1960	acyl-CoA dehydrogenase activity
CWD84_RS11805	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS11810	COG0439	Biotin carboxylase
CWD84_RS11815	COG0511	ligase activity, forming carbon-carbon bonds
CWD84_RS11820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWD84_RS11825	COG1024	Enoyl-CoA hydratase
CWD84_RS11830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWD84_RS11835	COG0586	Pfam SNARE associated Golgi protein
CWD84_RS11840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWD84_RS11845	COG2246	polysaccharide biosynthetic process
CWD84_RS11855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWD84_RS11875	COG2124	cytochrome p450
CWD84_RS11880	COG2610	gluconate transmembrane transporter activity
CWD84_RS11885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CWD84_RS11890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWD84_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS11920	COG3507	Belongs to the glycosyl hydrolase 43 family
CWD84_RS11965	COG1115	amino acid carrier protein
CWD84_RS11975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWD84_RS11980	COG0187	DNA topoisomerase II activity
CWD84_RS11985	COG1832	CoA-binding protein
CWD84_RS11995	COG4841	protein insertion into membrane
CWD84_RS12005	COG0824	Thioesterase
CWD84_RS12025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS12030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWD84_RS12045	COG0071	Belongs to the small heat shock protein (HSP20) family
CWD84_RS12055	COG4846	Membrane protein involved in cytochrome C biogenesis
CWD84_RS12060	COG2201	protein-glutamate methylesterase activity
CWD84_RS12065	COG0785	Cytochrome C biogenesis protein
CWD84_RS12085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWD84_RS12095	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWD84_RS12130	COG4195	phage-related replication protein
CWD84_RS12135	COG0756	dUTP diphosphatase activity
CWD84_RS12140	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS12165	COG3397	chitin binding
CWD84_RS12185	COG0456	acetyltransferase
CWD84_RS12205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CWD84_RS12205	COG4451	ribulose bisphosphate carboxylase, small
CWD84_RS12210	COG1064	alcohol dehydrogenase
CWD84_RS12215	COG2318	DinB family
CWD84_RS12220	COG2378	regulation of single-species biofilm formation
CWD84_RS12235	COG0574	Belongs to the PEP-utilizing enzyme family
CWD84_RS12235	COG3848	Pyruvate phosphate dikinase
CWD84_RS12240	COG1070	Carbohydrate kinase
CWD84_RS12255	COG3507	Belongs to the glycosyl hydrolase 43 family
CWD84_RS12260	COG2211	Major facilitator Superfamily
CWD84_RS12280	COG5444	nuclease activity
CWD84_RS12315	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS12315	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS12345	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS12350	COG1705	Flagellar rod assembly protein muramidase FlgJ
CWD84_RS12360	COG3953	SLT domain
CWD84_RS12360	COG5412	phage tail tape measure protein
CWD84_RS12510	COG3646	Phage regulatory protein
CWD84_RS12510	COG3645	SOS response
CWD84_RS12520	COG1396	sequence-specific DNA binding
CWD84_RS12530	COG4974	Belongs to the 'phage' integrase family
CWD84_RS12535	COG0174	glutamine synthetase
CWD84_RS12540	COG0789	Transcriptional regulator
CWD84_RS12545	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CWD84_RS12550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWD84_RS12555	COG0464	growth
CWD84_RS12565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS12570	COG4112	unkown
CWD84_RS12575	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWD84_RS12580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWD84_RS12620	COG2076	Multidrug Resistance protein
CWD84_RS12630	COG1764	response to oxidative stress
CWD84_RS12635	COG4195	phage-related replication protein
CWD84_RS12645	COG1404	Belongs to the peptidase S8 family
CWD84_RS12660	COG3619	membrane
CWD84_RS12665	COG3209	COG3209 Rhs family protein
CWD84_RS12670	COG2124	cytochrome p450
CWD84_RS12675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS12675	COG3321	synthase
CWD84_RS12675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CWD84_RS12675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWD84_RS12680	COG3321	synthase
CWD84_RS12680	COG4221	oxidoreductase activity
CWD84_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS12680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS12685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS12685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS12685	COG3321	synthase
CWD84_RS12685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS12685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS12685	COG3321	synthase
CWD84_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS12685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS12685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS12690	COG0300	oxidoreductase activity
CWD84_RS12690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS12690	COG4221	oxidoreductase activity
CWD84_RS12690	COG3321	synthase
CWD84_RS12695	COG0300	oxidoreductase activity
CWD84_RS12695	COG3321	synthase
CWD84_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS12695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS12695	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS12700	COG1024	Enoyl-CoA hydratase
CWD84_RS12705	COG1024	Enoyl-CoA hydratase
CWD84_RS12710	COG3425	synthase
CWD84_RS12715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS12750	COG5444	nuclease activity
CWD84_RS12795	COG4550	Control of competence regulator ComK, YlbF/YmcA
CWD84_RS12815	COG2359	stage V sporulation protein S
CWD84_RS12820	COG1692	metallophosphoesterase
CWD84_RS12830	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWD84_RS12845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWD84_RS12850	COG1426	Protein conserved in bacteria
CWD84_RS12865	COG0300	oxidoreductase activity
CWD84_RS12870	COG0612	Peptidase, M16
CWD84_RS12875	COG0612	Peptidase, M16
CWD84_RS12880	COG2409	Drug exporters of the RND superfamily
CWD84_RS12880	COG1033	growth of symbiont in host cell
CWD84_RS12885	COG1846	Transcriptional regulator
CWD84_RS12890	COG2814	Major facilitator Superfamily
CWD84_RS12895	COG2188	Transcriptional regulator
CWD84_RS12900	COG1674	ftsk spoiiie
CWD84_RS12900	COG4980	gas vesicle protein
CWD84_RS12910	COG0740	serine-type endopeptidase activity
CWD84_RS12915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CWD84_RS12925	COG0527	aspartate kinase activity
CWD84_RS12930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWD84_RS12935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWD84_RS12940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWD84_RS12945	COG1873	PFAM PRC-barrel domain
CWD84_RS12950	COG0612	Peptidase, M16
CWD84_RS12955	COG0726	polysaccharide deacetylase
CWD84_RS12970	COG0196	riboflavin kinase activity
CWD84_RS12985	COG1550	Protein conserved in bacteria
CWD84_RS12995	COG1358	cellular component organization or biogenesis
CWD84_RS13000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CWD84_RS13005	COG0195	Participates in both transcription termination and antitermination
CWD84_RS13015	COG2176	DNA-directed DNA polymerase activity
CWD84_RS13025	COG0750	zinc metalloprotease
CWD84_RS13035	COG4589	Belongs to the CDS family
CWD84_RS13040	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWD84_RS13070	COG1191	sigma factor activity
CWD84_RS13080	COG1776	CheC inhibitor of MCP methylation
CWD84_RS13085	COG0835	chemotaxis
CWD84_RS13090	COG2198	Histidine kinase
CWD84_RS13090	COG0643	Histidine kinase
CWD84_RS13095	COG2201	protein-glutamate methylesterase activity
CWD84_RS13100	COG0455	bacterial-type flagellum organization
CWD84_RS13105	COG1419	protein localization to endoplasmic reticulum
CWD84_RS13110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CWD84_RS13115	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CWD84_RS13120	COG1684	flagellar biosynthetic protein fliR
CWD84_RS13125	COG1987	bacterial-type flagellum assembly
CWD84_RS13130	COG1338	Plays a role in the flagellum-specific transport system
CWD84_RS13135	COG3190	flagellar
CWD84_RS13140	COG2201	protein-glutamate methylesterase activity
CWD84_RS13145	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CWD84_RS13145	COG1776	CheC inhibitor of MCP methylation
CWD84_RS13150	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CWD84_RS13155	COG1580	Controls the rotational direction of flagella during chemotaxis
CWD84_RS13160	COG1582	Flagellar protein (FlbD)
CWD84_RS13165	COG4786	Flagellar basal body rod
CWD84_RS13170	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CWD84_RS13175	COG3144	bacterial-type flagellum assembly
CWD84_RS13180	COG3334	PFAM MgtE intracellular
CWD84_RS13185	COG2882	bacterial-type flagellum organization
CWD84_RS13190	COG1157	protein secretion by the type III secretion system
CWD84_RS13195	COG1317	bacterial-type flagellum organization
CWD84_RS13200	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CWD84_RS13205	COG1766	The M ring may be actively involved in energy transduction
CWD84_RS13210	COG1677	Flagellar hook-basal body complex protein FliE
CWD84_RS13215	COG1558	bacterial-type flagellum-dependent cell motility
CWD84_RS13220	COG1815	bacterial-type flagellum-dependent cell motility
CWD84_RS13240	COG4974	Belongs to the 'phage' integrase family
CWD84_RS13250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWD84_RS13255	COG0758	DNA mediated transformation
CWD84_RS13260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CWD84_RS13270	COG2257	FlhB HrpN YscU SpaS Family
CWD84_RS13285	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWD84_RS13310	COG1837	Belongs to the UPF0109 family
CWD84_RS13320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWD84_RS13335	COG0552	protein localization to endoplasmic reticulum
CWD84_RS13340	COG1196	nuclear chromosome segregation
CWD84_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS13360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWD84_RS13375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWD84_RS13380	COG1760	l-serine dehydratase
CWD84_RS13385	COG1760	l-serine dehydratase
CWD84_RS13390	COG1461	Dihydroxyacetone kinase
CWD84_RS13395	COG1302	Protein conserved in bacteria
CWD84_RS13410	COG1564	THIamine pyrophosphokinase
CWD84_RS13415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWD84_RS13425	COG0515	serine threonine protein kinase
CWD84_RS13425	COG2815	serine threonine protein kinase
CWD84_RS13430	COG0631	protein serine/threonine phosphatase activity
CWD84_RS13440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWD84_RS13440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWD84_RS13450	COG0242	peptide deformylase activity
CWD84_RS13455	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWD84_RS13460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWD84_RS13470	COG0194	GDP metabolic process
CWD84_RS13480	COG1561	YicC-like family, N-terminal region
CWD84_RS13485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWD84_RS13500	COG1648	precorrin-2 dehydrogenase activity
CWD84_RS13505	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CWD84_RS13510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWD84_RS13525	COG0306	phosphate transporter
CWD84_RS13535	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CWD84_RS13540	COG0284	orotidine-5'-phosphate decarboxylase activity
CWD84_RS13555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWD84_RS13560	COG0505	Belongs to the CarA family
CWD84_RS13565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWD84_RS13575	COG2233	PERMEase
CWD84_RS13585	COG0564	pseudouridine synthase activity
CWD84_RS13595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CWD84_RS13600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CWD84_RS13610	COG3599	regulation of cell shape
CWD84_RS13615	COG2302	S4 RNA-binding domain
CWD84_RS13620	COG0762	integral membrane protein
CWD84_RS13630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWD84_RS13635	COG1496	oxidoreductase activity
CWD84_RS13640	COG1873	PFAM PRC-barrel domain
CWD84_RS13645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWD84_RS13650	COG1119	ATPase activity
CWD84_RS13655	COG1191	sigma factor activity
CWD84_RS13660	COG1191	sigma factor activity
CWD84_RS13670	COG4412	M6 family metalloprotease domain protein
CWD84_RS13670	COG1404	Belongs to the peptidase S8 family
CWD84_RS13675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWD84_RS13680	COG0849	cell division
CWD84_RS13685	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CWD84_RS13700	COG0772	Belongs to the SEDS family
CWD84_RS13720	COG0768	penicillin binding
CWD84_RS13725	COG0768	penicillin binding
CWD84_RS13730	COG4839	cell division protein FtsL
CWD84_RS13750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWD84_RS13770	COG1399	metal-binding, possibly nucleic acid-binding protein
CWD84_RS13780	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWD84_RS13785	COG1752	Esterase of the alpha-beta hydrolase superfamily
CWD84_RS13790	COG3314	Sporulation integral membrane protein YlbJ
CWD84_RS13800	COG0742	ribosomal rna small subunit methyltransferase
CWD84_RS13810	COG3679	Belongs to the UPF0342 family
CWD84_RS13825	COG2340	Cysteine-rich secretory protein family
CWD84_RS13830	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
CWD84_RS13840	COG3336	cytochrome c oxidase
CWD84_RS13845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CWD84_RS13850	COG1845	cytochrome c oxidase, subunit III
CWD84_RS13855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWD84_RS13860	COG2010	Cytochrome c
CWD84_RS13860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWD84_RS13875	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWD84_RS13880	COG0772	Belongs to the SEDS family
CWD84_RS13890	COG2066	Belongs to the glutaminase family
CWD84_RS13895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWD84_RS13900	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CWD84_RS13910	COG4896	Protein conserved in bacteria
CWD84_RS13920	COG1217	gtp-binding protein TYPA
CWD84_RS13945	COG1595	DNA-templated transcription, initiation
CWD84_RS13960	COG3227	Zinc metalloprotease (Elastase)
CWD84_RS13970	COG0483	inositol monophosphate 1-phosphatase activity
CWD84_RS13995	COG1982	Orn Lys Arg decarboxylase major
CWD84_RS14010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS14015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWD84_RS14020	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWD84_RS14025	COG0022	dehydrogenase e1 component
CWD84_RS14030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWD84_RS14035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWD84_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS14040	COG4221	oxidoreductase activity
CWD84_RS14040	COG3321	synthase
CWD84_RS14045	COG4221	oxidoreductase activity
CWD84_RS14045	COG0300	oxidoreductase activity
CWD84_RS14045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS14045	COG3321	synthase
CWD84_RS14050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS14050	COG4221	oxidoreductase activity
CWD84_RS14050	COG3321	synthase
CWD84_RS14050	COG0300	oxidoreductase activity
CWD84_RS14055	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS14055	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14055	COG3321	synthase
CWD84_RS14055	COG0300	oxidoreductase activity
CWD84_RS14055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS14060	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS14060	COG4221	oxidoreductase activity
CWD84_RS14060	COG3321	synthase
CWD84_RS14065	COG0300	oxidoreductase activity
CWD84_RS14065	COG3321	synthase
CWD84_RS14065	COG4221	oxidoreductase activity
CWD84_RS14065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWD84_RS14070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS14070	COG3321	synthase
CWD84_RS14070	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14070	COG4221	oxidoreductase activity
CWD84_RS14075	COG2070	2-Nitropropane dioxygenase
CWD84_RS14075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWD84_RS14085	COG0497	DNA recombination
CWD84_RS14095	COG0242	peptide deformylase activity
CWD84_RS14100	COG0561	phosphatase activity
CWD84_RS14110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CWD84_RS14120	COG0569	domain protein
CWD84_RS14125	COG2105	PFAM AIG2 family protein
CWD84_RS14125	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CWD84_RS14130	COG3852	Histidine kinase
CWD84_RS14135	COG2002	toxin-antitoxin pair type II binding
CWD84_RS14145	COG1077	Cell shape determining protein MreB Mrl
CWD84_RS14155	COG2309	aminopeptidase activity
CWD84_RS14160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWD84_RS14165	COG0488	(ABC) transporter
CWD84_RS14175	COG0681	Belongs to the peptidase S26 family
CWD84_RS14180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWD84_RS14180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWD84_RS14180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWD84_RS14185	COG1105	Belongs to the carbohydrate kinase PfkB family
CWD84_RS14190	COG1349	DNA-binding transcription factor activity
CWD84_RS14195	COG0577	efflux transmembrane transporter activity
CWD84_RS14200	COG1136	(ABC) transporter
CWD84_RS14205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWD84_RS14215	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CWD84_RS14220	COG0314	molybdopterin synthase activity
CWD84_RS14225	COG1763	Mo-molybdopterin cofactor biosynthetic process
CWD84_RS14230	COG0303	'Molybdopterin
CWD84_RS14235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWD84_RS14255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS14260	COG0668	transmembrane transport
CWD84_RS14280	COG0716	FMN binding
CWD84_RS14290	COG0716	FMN binding
CWD84_RS14295	COG0583	DNA-binding transcription factor activity
CWD84_RS14300	COG0517	IMP dehydrogenase activity
CWD84_RS14310	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
CWD84_RS14315	COG4703	Protein of unknown function (DUF1797)
CWD84_RS14325	COG2200	EAL domain
CWD84_RS14335	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14340	COG1408	metallophosphoesterase
CWD84_RS14345	COG1376	ErfK ybiS ycfS ynhG family protein
CWD84_RS14350	COG2814	Major facilitator Superfamily
CWD84_RS14360	COG0835	chemotaxis
CWD84_RS14360	COG0784	Response regulator, receiver
CWD84_RS14365	COG0436	Aminotransferase
CWD84_RS14370	COG4191	Histidine kinase
CWD84_RS14375	COG0768	penicillin binding
CWD84_RS14380	COG2340	Cysteine-rich secretory protein family
CWD84_RS14390	COG2084	Dehydrogenase
CWD84_RS14395	COG0840	transmembrane signaling receptor activity
CWD84_RS14400	COG1533	DNA photolyase activity
CWD84_RS14410	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CWD84_RS14415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWD84_RS14420	COG2190	(PTS) system
CWD84_RS14420	COG1263	PTS System
CWD84_RS14420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWD84_RS14425	COG3711	transcriptional antiterminator
CWD84_RS14430	COG1609	Transcriptional regulator
CWD84_RS14435	COG0006	proline dipeptidase activity
CWD84_RS14440	COG2217	Heavy metal translocating P-type atpase
CWD84_RS14445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS14450	COG2244	polysaccharide biosynthetic process
CWD84_RS14455	COG3773	Cell wall hydrolase
CWD84_RS14465	COG4873	Protein conserved in bacteria
CWD84_RS14480	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS14485	COG1733	regulation of RNA biosynthetic process
CWD84_RS14490	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CWD84_RS14495	COG0602	queuosine metabolic process
CWD84_RS14500	COG0720	synthase
CWD84_RS14515	COG3949	Membrane
CWD84_RS14520	COG0542	response to heat
CWD84_RS14525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CWD84_RS14530	COG1360	Flagellar Motor Protein
CWD84_RS14535	COG1846	Transcriptional regulator
CWD84_RS14540	COG3852	Histidine kinase
CWD84_RS14570	COG0436	Aminotransferase
CWD84_RS14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWD84_RS14590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWD84_RS14595	COG5002	protein histidine kinase activity
CWD84_RS14600	COG3594	Acyltransferase
CWD84_RS14610	COG2323	membrane
CWD84_RS14615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWD84_RS14640	COG1191	sigma factor activity
CWD84_RS14645	COG0861	Integral membrane protein TerC family
CWD84_RS14650	COG0586	Pfam SNARE associated Golgi protein
CWD84_RS14655	COG5001	Diguanylate cyclase
CWD84_RS14655	COG3300	MHYT domain
CWD84_RS14660	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CWD84_RS14665	COG1793	dna ligase
CWD84_RS14665	COG3285	dna ligase
CWD84_RS14670	COG0726	polysaccharide deacetylase
CWD84_RS14675	COG1846	Transcriptional regulator
CWD84_RS14690	COG0789	Transcriptional regulator
CWD84_RS14695	COG2239	Acts as a magnesium transporter
CWD84_RS14700	COG1388	LysM domain
CWD84_RS14700	COG3858	chitin binding
CWD84_RS14705	COG4721	ABC-type cobalt transport system, permease component
CWD84_RS14710	COG1122	ATPase activity
CWD84_RS14715	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWD84_RS14720	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS14725	COG1404	Belongs to the peptidase S8 family
CWD84_RS14740	COG2814	Major facilitator Superfamily
CWD84_RS14745	COG0590	tRNA wobble adenosine to inosine editing
CWD84_RS14755	COG0463	Glycosyl transferase, family 2
CWD84_RS14755	COG0457	Tetratricopeptide repeat
CWD84_RS14770	COG1764	response to oxidative stress
CWD84_RS14775	COG1846	Transcriptional regulator
CWD84_RS14780	COG1764	response to oxidative stress
CWD84_RS14790	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWD84_RS14795	COG0788	formyltetrahydrofolate deformylase activity
CWD84_RS14800	COG2076	Multidrug Resistance protein
CWD84_RS14805	COG2076	Multidrug Resistance protein
CWD84_RS14810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWD84_RS14815	COG1607	acyl-coa hydrolase
CWD84_RS14820	COG1834	amidinotransferase
CWD84_RS14825	COG2706	6-phosphogluconolactonase activity
CWD84_RS14830	COG4608	Belongs to the ABC transporter superfamily
CWD84_RS14835	COG0791	NLP P60 protein
CWD84_RS14840	COG4948	Mandelate Racemase Muconate Lactonizing
CWD84_RS14845	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWD84_RS14850	COG4166	transmembrane transport
CWD84_RS14855	COG0444	Belongs to the ABC transporter superfamily
CWD84_RS14860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWD84_RS14865	COG0601	transmembrane transport
CWD84_RS14870	COG2362	D-Aminopeptidase
CWD84_RS14875	COG0477	Major facilitator Superfamily
CWD84_RS14880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWD84_RS14885	COG0463	Glycosyl transferase, family 2
CWD84_RS14890	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CWD84_RS14895	COG0346	lactoylglutathione lyase activity
CWD84_RS14900	COG0531	amino acid
CWD84_RS14905	COG1392	Phosphate transport regulator
CWD84_RS14910	COG0306	phosphate transporter
CWD84_RS14925	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS14925	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS14965	COG3778	Protein conserved in bacteria
CWD84_RS14970	COG3299	homolog of phage Mu protein gp47
CWD84_RS14975	COG3628	GPW Gp25 family protein
CWD84_RS14985	COG4193	domain, Protein
CWD84_RS14990	COG1652	LysM domain
CWD84_RS14995	COG5412	phage tail tape measure protein
CWD84_RS14995	COG5412	phage tail tape measure protein
CWD84_RS14995	COG3953	SLT domain
CWD84_RS14995	COG5412	phage tail tape measure protein
CWD84_RS14995	COG3953	SLT domain
CWD84_RS14995	COG3953	SLT domain
CWD84_RS15045	COG4653	Phage capsid family
CWD84_RS15050	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CWD84_RS15055	COG5518	Phage portal protein
CWD84_RS15060	COG1783	phage Terminase large subunit
CWD84_RS15065	COG5484	DNA packaging
CWD84_RS15065	COG3728	DNA packaging
CWD84_RS15070	COG1595	DNA-templated transcription, initiation
CWD84_RS15085	COG1484	DNA-dependent DNA replication
CWD84_RS15090	COG1522	sequence-specific DNA binding
CWD84_RS15100	COG1396	sequence-specific DNA binding
CWD84_RS15105	COG2856	Zn peptidase
CWD84_RS15110	COG4195	phage-related replication protein
CWD84_RS15125	COG0457	Tetratricopeptide repeat
CWD84_RS15130	COG2318	DinB family
CWD84_RS15135	COG0730	response to heat
CWD84_RS15145	COG1609	Transcriptional regulator
CWD84_RS15155	COG1252	NADH dehydrogenase
CWD84_RS15165	COG4297	protein containing double-stranded beta helix domain
CWD84_RS15170	COG0697	spore germination
CWD84_RS15175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWD84_RS15180	COG0390	transport system, permease component
CWD84_RS15185	COG1587	Uroporphyrinogen-III synthase
CWD84_RS15195	COG1819	glycosyl
CWD84_RS15200	COG2124	cytochrome p450
CWD84_RS15205	COG2427	Protein of unknown function (DUF1641)
CWD84_RS15210	COG3383	formate dehydrogenase (NAD+) activity
CWD84_RS15220	COG2205	protein histidine kinase activity
CWD84_RS15230	COG1285	pathogenesis
CWD84_RS15250	COG1349	DNA-binding transcription factor activity
CWD84_RS15255	COG2723	6-phospho-beta-galactosidase activity
CWD84_RS15260	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWD84_RS15265	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWD84_RS15265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWD84_RS15270	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWD84_RS15275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWD84_RS15280	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWD84_RS15290	COG1846	Transcriptional regulator
CWD84_RS15295	COG2814	Major facilitator Superfamily
CWD84_RS15300	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CWD84_RS15305	COG2367	Beta-lactamase
CWD84_RS15455	COG4824	toxin secretion phage lysis holin
CWD84_RS15575	COG5484	DNA packaging
CWD84_RS15600	COG1595	DNA-templated transcription, initiation
CWD84_RS15675	COG1484	DNA-dependent DNA replication
CWD84_RS15680	COG3935	DnaD domain protein
CWD84_RS15740	COG1396	sequence-specific DNA binding
CWD84_RS15755	COG2856	Zn peptidase
CWD84_RS15760	COG0582	viral genome integration into host DNA
CWD84_RS15770	COG0626	cystathionine gamma-synthase activity
CWD84_RS15775	COG0626	cystathionine gamma-synthase activity
CWD84_RS15780	COG2382	esterase
CWD84_RS15790	COG2153	protein acetylation
CWD84_RS15800	COG1131	(ABC) transporter
CWD84_RS15820	COG0210	DNA helicase
CWD84_RS15875	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWD84_RS15880	COG0351	phosphomethylpyrimidine kinase
CWD84_RS15885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWD84_RS15895	COG2104	thiamine diphosphate biosynthetic process
CWD84_RS15900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWD84_RS15905	COG0352	thiamine-phosphate diphosphorylase activity
CWD84_RS15910	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CWD84_RS15915	COG0569	domain protein
CWD84_RS15915	COG0475	glutathione-regulated potassium exporter activity
CWD84_RS15925	COG0564	pseudouridine synthase activity
CWD84_RS15930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CWD84_RS15935	COG2357	RelA SpoT domain protein
CWD84_RS15945	COG4116	CYTH
CWD84_RS15950	COG0741	lytic transglycosylase activity
CWD84_RS15955	COG2346	COG2346, Truncated hemoglobins
CWD84_RS15960	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CWD84_RS15965	COG1164	Oligoendopeptidase f
CWD84_RS15970	COG4469	Competence protein
CWD84_RS15975	COG4862	establishment of competence for transformation
CWD84_RS15980	COG0861	Integral membrane protein TerC family
CWD84_RS15985	COG1393	Belongs to the ArsC family
CWD84_RS15990	COG0456	acetyltransferase
CWD84_RS16000	COG4608	Belongs to the ABC transporter superfamily
CWD84_RS16005	COG0444	Belongs to the ABC transporter superfamily
CWD84_RS16010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWD84_RS16015	COG0601	transmembrane transport
CWD84_RS16020	COG4166	transmembrane transport
CWD84_RS16030	COG0180	Tryptophanyl-tRNA synthetase
CWD84_RS16040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWD84_RS16045	COG0601	transmembrane transport
CWD84_RS16055	COG4608	Belongs to the ABC transporter superfamily
CWD84_RS16060	COG0444	Belongs to the ABC transporter superfamily
CWD84_RS16065	COG5504	Zn-dependent protease
CWD84_RS16070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWD84_RS16075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWD84_RS16090	COG1744	ABC transporter substrate-binding protein PnrA-like
CWD84_RS16120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWD84_RS16125	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWD84_RS16130	COG0505	Belongs to the CarA family
CWD84_RS16135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWD84_RS16145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CWD84_RS16155	COG2271	Major facilitator Superfamily
CWD84_RS16160	COG0277	FAD linked oxidase domain protein
CWD84_RS16170	COG2151	metal-sulfur cluster biosynthetic enzyme
CWD84_RS16175	COG1073	alpha beta
CWD84_RS16180	COG0561	phosphatase activity
CWD84_RS16195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS16200	COG1307	EDD domain protein, DegV family
CWD84_RS16210	COG2996	Protein conserved in bacteria
CWD84_RS16220	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CWD84_RS16220	COG0646	methionine synthase
CWD84_RS16230	COG1357	PFAM Pentapeptide repeats (8 copies)
CWD84_RS16235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWD84_RS16240	COG1279	arginine transmembrane transporter activity
CWD84_RS16245	COG2318	DinB family
CWD84_RS16250	COG1917	Cupin 2, conserved barrel domain protein
CWD84_RS16250	COG2207	Transcriptional regulator
CWD84_RS16255	COG0534	Mate efflux family protein
CWD84_RS16260	COG1562	ergosterol biosynthetic process
CWD84_RS16265	COG0367	asparagine synthase
CWD84_RS16285	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWD84_RS16325	COG1403	HNH endonuclease
CWD84_RS16330	COG0419	ATPase involved in DNA repair
CWD84_RS16335	COG0420	3'-5' exonuclease activity
CWD84_RS16350	COG2323	membrane
CWD84_RS16355	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CWD84_RS16365	COG2814	Major facilitator Superfamily
CWD84_RS16370	COG3180	Ammonia monooxygenase
CWD84_RS16375	COG1846	Transcriptional regulator
CWD84_RS16380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWD84_RS16385	COG0681	Belongs to the peptidase S26 family
CWD84_RS16390	COG0398	Pfam SNARE associated Golgi protein
CWD84_RS16405	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWD84_RS16425	COG5646	InterPro IPR014922
CWD84_RS16430	COG4903	ComK protein
CWD84_RS16440	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS16445	COG0723	plastoquinol--plastocyanin reductase activity
CWD84_RS16445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWD84_RS16450	COG0840	transmembrane signaling receptor activity
CWD84_RS16455	COG1268	BioY protein
CWD84_RS16460	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS16465	COG0183	Belongs to the thiolase family
CWD84_RS16470	COG0406	alpha-ribazole phosphatase activity
CWD84_RS16475	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CWD84_RS16485	COG1404	Belongs to the peptidase S8 family
CWD84_RS16490	COG0501	Belongs to the peptidase M48B family
CWD84_RS16500	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS16505	COG0702	epimerase
CWD84_RS16510	COG0095	Lipoate-protein ligase
CWD84_RS16515	COG1234	tRNA 3'-trailer cleavage
CWD84_RS16525	COG1301	dicarboxylic acid transport
CWD84_RS16530	COG1363	Peptidase, m42
CWD84_RS16540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWD84_RS16545	COG1511	domain protein
CWD84_RS16550	COG1309	transcriptional regulator
CWD84_RS16555	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CWD84_RS16560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CWD84_RS16570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWD84_RS16575	COG2329	Antibiotic biosynthesis monooxygenase
CWD84_RS16580	COG3069	C4-dicarboxylate transmembrane transporter activity
CWD84_RS16585	COG1473	amidohydrolase
CWD84_RS16595	COG4473	ABC transporter
CWD84_RS16600	COG1131	(ABC) transporter
CWD84_RS16605	COG0537	adenosine 5'-monophosphoramidase activity
CWD84_RS16610	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CWD84_RS16625	COG4980	gas vesicle protein
CWD84_RS16665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWD84_RS16680	COG4717	serine-type aminopeptidase activity
CWD84_RS16685	COG0420	3'-5' exonuclease activity
CWD84_RS16690	COG1668	transmembrane transport
CWD84_RS16695	COG4152	abc transporter atp-binding protein
CWD84_RS16705	COG1024	Enoyl-CoA hydratase
CWD84_RS16715	COG0490	domain, Protein
CWD84_RS16720	COG0475	glutathione-regulated potassium exporter activity
CWD84_RS16730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWD84_RS16735	COG0561	phosphatase activity
CWD84_RS16740	COG4335	DNA alkylation repair
CWD84_RS16755	COG0189	ligase activity
CWD84_RS16760	COG0189	ligase activity
CWD84_RS16780	COG0702	epimerase
CWD84_RS16785	COG1132	(ABC) transporter
CWD84_RS16790	COG1132	(ABC) transporter
CWD84_RS16795	COG0589	response to stress
CWD84_RS16805	COG3226	Transcriptional regulator
CWD84_RS16810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS16815	COG0726	polysaccharide deacetylase
CWD84_RS16820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CWD84_RS16825	COG0668	transmembrane transport
CWD84_RS16835	COG0584	glycerophosphoryl diester phosphodiesterase
CWD84_RS16840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWD84_RS16845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWD84_RS16850	COG1253	flavin adenine dinucleotide binding
CWD84_RS16855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWD84_RS16860	COG0436	Aminotransferase
CWD84_RS16865	COG0789	Transcriptional regulator
CWD84_RS16870	COG1253	flavin adenine dinucleotide binding
CWD84_RS16875	COG0204	Acyl-transferase
CWD84_RS16880	COG1595	DNA-templated transcription, initiation
CWD84_RS16900	COG0733	neurotransmitter:sodium symporter activity
CWD84_RS16905	COG0531	amino acid
CWD84_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS16920	COG0372	Belongs to the citrate synthase family
CWD84_RS16925	COG0583	DNA-binding transcription factor activity
CWD84_RS16930	COG0791	NLP P60 protein
CWD84_RS16930	COG1388	LysM domain
CWD84_RS16935	COG1785	Belongs to the alkaline phosphatase family
CWD84_RS16940	COG2719	SpoVR family
CWD84_RS16945	COG0668	transmembrane transport
CWD84_RS16950	COG1959	2 iron, 2 sulfur cluster binding
CWD84_RS16955	COG1388	LysM domain
CWD84_RS16955	COG0791	NLP P60 protein
CWD84_RS16970	COG0431	NADPH-dependent FMN reductase
CWD84_RS16980	COG2203	Gaf domain
CWD84_RS16980	COG4585	Histidine kinase
CWD84_RS16985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWD84_RS16990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWD84_RS17000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWD84_RS17005	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CWD84_RS17010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWD84_RS17015	COG3153	acetyltransferase
CWD84_RS17015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWD84_RS17020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWD84_RS17025	COG0517	IMP dehydrogenase activity
CWD84_RS17035	COG0564	pseudouridine synthase activity
CWD84_RS17040	COG3764	Sortase (surface protein transpeptidase)
CWD84_RS17045	COG4085	toxin activity
CWD84_RS17045	COG1525	nuclease
CWD84_RS17045	COG0737	Belongs to the 5'-nucleotidase family
CWD84_RS17050	COG5577	PFAM Coat F domain
CWD84_RS17070	COG1823	symporter activity
CWD84_RS17075	COG3706	GGDEF domain
CWD84_RS17090	COG1278	Cold shock
CWD84_RS17095	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CWD84_RS17100	COG1131	(ABC) transporter
CWD84_RS17105	COG1131	(ABC) transporter
CWD84_RS17110	COG1725	Transcriptional regulator
CWD84_RS17125	COG0655	NAD(P)H dehydrogenase (quinone) activity
CWD84_RS17130	COG2814	Major facilitator Superfamily
CWD84_RS17135	COG1566	PFAM secretion protein HlyD family protein
CWD84_RS17140	COG1846	Transcriptional regulator
CWD84_RS17150	COG2766	serine protein kinase
CWD84_RS17160	COG1664	Polymer-forming cytoskeletal
CWD84_RS17165	COG1664	Polymer-forming cytoskeletal
CWD84_RS17170	COG0789	Transcriptional regulator
CWD84_RS17175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CWD84_RS17185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWD84_RS17190	COG3382	B3 4 domain protein
CWD84_RS17200	COG1476	TRANSCRIPTIONal
CWD84_RS17225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWD84_RS17230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWD84_RS17235	COG1116	anion transmembrane transporter activity
CWD84_RS17245	COG0753	catalase activity
CWD84_RS17250	COG4608	Belongs to the ABC transporter superfamily
CWD84_RS17255	COG0444	Belongs to the ABC transporter superfamily
CWD84_RS17260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWD84_RS17265	COG0601	transmembrane transport
CWD84_RS17270	COG4166	transmembrane transport
CWD84_RS17280	COG0277	FAD linked oxidase domain protein
CWD84_RS17290	COG3340	Belongs to the peptidase S51 family
CWD84_RS17440	COG0735	belongs to the Fur family
CWD84_RS17445	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CWD84_RS17455	COG4129	membrane
CWD84_RS17460	COG1132	(ABC) transporter
CWD84_RS17480	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS17490	COG1194	a g-specific adenine glycosylase
CWD84_RS17495	COG0457	Tetratricopeptide repeat
CWD84_RS17555	COG5280	Phage tail tape measure protein TP901
CWD84_RS17555	COG3953	SLT domain
CWD84_RS17595	COG0740	serine-type endopeptidase activity
CWD84_RS17650	COG1595	DNA-templated transcription, initiation
CWD84_RS17660	COG0305	Participates in initiation and elongation during chromosome replication
CWD84_RS17685	COG3646	Phage regulatory protein
CWD84_RS17685	COG3645	SOS response
CWD84_RS17720	COG0582	viral genome integration into host DNA
CWD84_RS17730	COG1988	membrane-bound metal-dependent
CWD84_RS17735	COG4485	Bacterial membrane protein, YfhO
CWD84_RS17740	COG0463	Glycosyl transferase, family 2
CWD84_RS17745	COG0596	Alpha beta hydrolase
CWD84_RS17750	COG5658	integral membrane protein
CWD84_RS17755	COG3103	Sh3 type 3 domain protein
CWD84_RS17770	COG2814	Major facilitator Superfamily
CWD84_RS17785	COG1090	epimerase
CWD84_RS17800	COG0778	Nitroreductase
CWD84_RS17805	COG0384	phenazine biosynthesis protein PhzF
CWD84_RS17810	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CWD84_RS17810	COG0392	lysyltransferase activity
CWD84_RS17815	COG1846	Transcriptional regulator
CWD84_RS17820	COG2814	Major facilitator Superfamily
CWD84_RS17825	COG2318	DinB family
CWD84_RS17830	COG2732	(Barnase) inhibitor
CWD84_RS17835	COG0574	Belongs to the PEP-utilizing enzyme family
CWD84_RS17835	COG3848	Pyruvate phosphate dikinase
CWD84_RS17840	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CWD84_RS17845	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWD84_RS17850	COG1695	Transcriptional regulator
CWD84_RS17865	COG2514	catechol 2,3-dioxygenase activity
CWD84_RS17870	COG2259	Doxx family
CWD84_RS17875	COG1132	(ABC) transporter
CWD84_RS17880	COG1132	(ABC) transporter
CWD84_RS17885	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS17890	COG1263	PTS System
CWD84_RS17890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWD84_RS17895	COG1737	Transcriptional regulator
CWD84_RS17900	COG1486	melibiose metabolic process
CWD84_RS17910	COG3284	Transcriptional regulator
CWD84_RS17915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWD84_RS17920	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWD84_RS17925	COG0022	dehydrogenase e1 component
CWD84_RS17930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWD84_RS17940	COG4637	Psort location Cytoplasmic, score
CWD84_RS17950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWD84_RS17960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWD84_RS17965	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CWD84_RS17970	COG0598	Magnesium transport protein CorA
CWD84_RS17980	COG2084	Dehydrogenase
CWD84_RS17985	COG0726	polysaccharide deacetylase
CWD84_RS17995	COG0535	radical SAM domain protein
CWD84_RS18000	COG0668	transmembrane transport
CWD84_RS18010	COG0387	Pfam Sodium calcium exchanger
CWD84_RS18015	COG0477	Major facilitator Superfamily
CWD84_RS18020	COG1295	ribonuclease BN
CWD84_RS18025	COG4980	gas vesicle protein
CWD84_RS18030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWD84_RS18040	COG2814	Major facilitator Superfamily
CWD84_RS18055	COG1609	Transcriptional regulator
CWD84_RS18060	COG0693	protein deglycase activity
CWD84_RS18065	COG0737	Belongs to the 5'-nucleotidase family
CWD84_RS18080	COG0778	Nitroreductase
CWD84_RS18100	COG0071	Belongs to the small heat shock protein (HSP20) family
CWD84_RS18110	COG1368	sulfuric ester hydrolase activity
CWD84_RS18120	COG1263	PTS System
CWD84_RS18120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWD84_RS18125	COG0024	Methionine aminopeptidase
CWD84_RS18145	COG2258	MOSC domain
CWD84_RS18155	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CWD84_RS18170	COG3181	Tripartite tricarboxylate transporter family receptor
CWD84_RS18175	COG4565	transcriptional regulatory protein
CWD84_RS18180	COG3290	protein histidine kinase activity
CWD84_RS18195	COG0471	metal ion transport
CWD84_RS18200	COG3866	Pectate lyase
CWD84_RS18215	COG2130	NADP-dependent
CWD84_RS18225	COG0513	Belongs to the DEAD box helicase family
CWD84_RS18230	COG0488	(ABC) transporter
CWD84_RS18235	COG2814	Major facilitator Superfamily
CWD84_RS18240	COG0789	Transcriptional regulator
CWD84_RS18260	COG0488	(ABC) transporter
CWD84_RS18265	COG0457	Tetratricopeptide repeat
CWD84_RS18265	COG0463	Glycosyl transferase, family 2
CWD84_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS18275	COG0840	transmembrane signaling receptor activity
CWD84_RS18280	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS18285	COG0531	amino acid
CWD84_RS18290	COG2223	nitrite transmembrane transporter activity
CWD84_RS18295	COG1442	glycosyl transferase family 8
CWD84_RS18300	COG1216	Glycosyl transferase, family 2
CWD84_RS18305	COG1442	glycosyl transferase family 8
CWD84_RS18310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWD84_RS18315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CWD84_RS18320	COG1368	sulfuric ester hydrolase activity
CWD84_RS18325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CWD84_RS18325	COG2124	cytochrome p450
CWD84_RS18335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWD84_RS18340	COG1846	Transcriptional regulator
CWD84_RS18345	COG0670	Belongs to the BI1 family
CWD84_RS18350	COG0196	riboflavin kinase activity
CWD84_RS18355	COG5583	Uncharacterized small protein (DUF2292)
CWD84_RS18360	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS18365	COG0346	lactoylglutathione lyase activity
CWD84_RS18370	COG2329	Antibiotic biosynthesis monooxygenase
CWD84_RS18375	COG2323	membrane
CWD84_RS18385	COG0454	-acetyltransferase
CWD84_RS18390	COG3546	catalase activity
CWD84_RS18415	COG5444	nuclease activity
CWD84_RS18455	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWD84_RS18460	COG1597	lipid kinase activity
CWD84_RS18465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWD84_RS18470	COG1309	transcriptional regulator
CWD84_RS18490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWD84_RS18495	COG1285	pathogenesis
CWD84_RS18500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CWD84_RS18505	COG4851	CamS sex pheromone cAM373 precursor
CWD84_RS18515	COG0210	DNA helicase
CWD84_RS18530	COG0069	glutamate synthase activity
CWD84_RS18535	COG4496	protein, YerC YecD
CWD84_RS18540	COG1470	cell adhesion involved in biofilm formation
CWD84_RS18545	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CWD84_RS18555	COG0151	Belongs to the GarS family
CWD84_RS18560	COG0138	bifunctional purine biosynthesis protein purh
CWD84_RS18565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWD84_RS18575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CWD84_RS18590	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWD84_RS18595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWD84_RS18600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWD84_RS18605	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWD84_RS18610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWD84_RS18630	COG3064	Membrane
CWD84_RS18635	COG2252	PERMEase
CWD84_RS18655	COG1305	Transglutaminase-like
CWD84_RS18660	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
CWD84_RS18665	COG0714	Associated with various cellular activities
CWD84_RS18680	COG1794	racemase activity, acting on amino acids and derivatives
CWD84_RS18685	COG2175	clavaminate synthase activity
CWD84_RS18690	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWD84_RS18705	COG0017	Asparaginyl-tRNA synthetase
CWD84_RS18715	COG1113	amino acid transport
CWD84_RS18720	COG2132	Multicopper oxidase
CWD84_RS18735	COG0823	Involved in the tonB-independent uptake of proteins
CWD84_RS18740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CWD84_RS18745	COG1063	alcohol dehydrogenase
CWD84_RS18750	COG1595	DNA-templated transcription, initiation
CWD84_RS18760	COG2755	lipolytic protein G-D-S-L family
CWD84_RS18760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CWD84_RS18765	COG4260	virion core protein, lumpy skin disease virus
CWD84_RS18770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CWD84_RS18775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWD84_RS18780	COG1842	Phage shock protein A
CWD84_RS18790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWD84_RS18795	COG2211	Major facilitator Superfamily
CWD84_RS18800	COG1063	alcohol dehydrogenase
CWD84_RS18805	COG0457	Tetratricopeptide repeat
CWD84_RS18830	COG1266	CAAX protease self-immunity
CWD84_RS18840	COG0805	protein transport
CWD84_RS18845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWD84_RS18860	COG0488	(ABC) transporter
CWD84_RS18865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWD84_RS18870	COG0456	acetyltransferase
CWD84_RS18875	COG1214	PFAM Peptidase M22, glycoprotease
CWD84_RS18880	COG0802	atpase or kinase
CWD84_RS18885	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CWD84_RS18925	COG2814	Major facilitator Superfamily
CWD84_RS18930	COG0604	alcohol dehydrogenase
CWD84_RS18935	COG3832	glyoxalase III activity
CWD84_RS18945	COG0531	amino acid
CWD84_RS18950	COG1309	transcriptional regulator
CWD84_RS18955	COG2076	Multidrug Resistance protein
CWD84_RS18960	COG2076	Multidrug Resistance protein
CWD84_RS18965	COG2807	transmembrane transport
CWD84_RS18970	COG2186	Transcriptional regulator
CWD84_RS18980	COG2814	Major facilitator Superfamily
CWD84_RS18985	COG1388	LysM domain
CWD84_RS18990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWD84_RS19005	COG1819	glycosyl
CWD84_RS19010	COG1802	Transcriptional regulator
CWD84_RS19015	COG0473	3-isopropylmalate dehydrogenase activity
CWD84_RS19020	COG0596	Alpha beta hydrolase
CWD84_RS19025	COG1051	belongs to the nudix hydrolase family
CWD84_RS19030	COG0456	acetyltransferase
CWD84_RS19035	COG0730	response to heat
CWD84_RS19045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWD84_RS19050	COG2814	Major facilitator Superfamily
CWD84_RS19060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWD84_RS19065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWD84_RS19070	COG0488	(ABC) transporter
CWD84_RS19075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWD84_RS19080	COG2409	Drug exporters of the RND superfamily
CWD84_RS19085	COG2197	response regulator
CWD84_RS19090	COG4585	Histidine kinase
CWD84_RS19095	COG0110	maltose O-acetyltransferase activity
CWD84_RS19105	COG0738	Major facilitator superfamily
CWD84_RS19115	COG5577	PFAM Coat F domain
CWD84_RS19120	COG1063	alcohol dehydrogenase
CWD84_RS19130	COG5577	PFAM Coat F domain
CWD84_RS19165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWD84_RS19175	COG0789	Transcriptional regulator
CWD84_RS19180	COG1064	alcohol dehydrogenase
CWD84_RS19195	COG2318	DinB family
CWD84_RS19200	COG0456	acetyltransferase
CWD84_RS19205	COG0662	Cupin 2, conserved barrel domain protein
CWD84_RS19225	COG0277	FAD linked oxidase domain protein
CWD84_RS19240	COG0662	Cupin 2, conserved barrel domain protein
CWD84_RS19250	COG3621	Patatin-like phospholipase
CWD84_RS19255	COG2271	Major facilitator Superfamily
CWD84_RS19260	COG1846	Transcriptional regulator
CWD84_RS19260	COG0456	acetyltransferase
CWD84_RS19280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWD84_RS19285	COG0477	Major facilitator Superfamily
CWD84_RS19305	COG2814	Major facilitator Superfamily
CWD84_RS19310	COG2807	transmembrane transport
CWD84_RS19320	COG0583	DNA-binding transcription factor activity
CWD84_RS19325	COG1329	Transcriptional regulator
CWD84_RS19330	COG1278	Cold shock
CWD84_RS19335	COG3381	protein complex oligomerization
CWD84_RS19345	COG2910	NAD(P)H-binding
CWD84_RS19350	COG1959	2 iron, 2 sulfur cluster binding
CWD84_RS19355	COG2030	dehydratase
CWD84_RS19365	COG1846	Transcriptional regulator
CWD84_RS19370	COG1764	response to oxidative stress
CWD84_RS19400	COG2249	NAD(P)H dehydrogenase (quinone) activity
CWD84_RS19420	COG1959	2 iron, 2 sulfur cluster binding
CWD84_RS19430	COG1660	Displays ATPase and GTPase activities
CWD84_RS19485	COG2183	response to ionizing radiation
CWD84_RS19490	COG2208	phosphoserine phosphatase activity
CWD84_RS19495	COG1191	sigma factor activity
CWD84_RS19505	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS19510	COG2208	phosphoserine phosphatase activity
CWD84_RS19515	COG2172	sigma factor antagonist activity
CWD84_RS19520	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS19525	COG1366	Belongs to the anti-sigma-factor antagonist family
CWD84_RS19530	COG2337	Toxic component of a toxin-antitoxin (TA) module
CWD84_RS19535	COG0864	Transcriptional regulator
CWD84_RS19540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWD84_RS19545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CWD84_RS19555	COG0705	Rhomboid family
CWD84_RS19560	COG3428	Bacterial PH domain
CWD84_RS19565	COG3402	PFAM membrane-flanked domain
CWD84_RS19570	COG0513	Belongs to the DEAD box helicase family
CWD84_RS19575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWD84_RS19585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS19590	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWD84_RS19605	COG1960	acyl-CoA dehydrogenase activity
CWD84_RS19615	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CWD84_RS19620	COG1131	(ABC) transporter
CWD84_RS19625	COG0628	permease
CWD84_RS19630	COG1301	dicarboxylic acid transport
CWD84_RS19635	COG4565	transcriptional regulatory protein
CWD84_RS19640	COG3290	protein histidine kinase activity
CWD84_RS19645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWD84_RS19650	COG3546	catalase activity
CWD84_RS19655	COG2329	Antibiotic biosynthesis monooxygenase
CWD84_RS19660	COG0662	Cupin 2, conserved barrel domain protein
CWD84_RS19665	COG3729	General stress protein
CWD84_RS19670	COG2217	Heavy metal translocating P-type atpase
CWD84_RS19675	COG2076	Multidrug Resistance protein
CWD84_RS19685	COG4876	unkown
CWD84_RS19700	COG1914	H( )-stimulated, divalent metal cation uptake system
CWD84_RS19745	COG0028	Belongs to the TPP enzyme family
CWD84_RS19750	COG0494	nUDIX hydrolase
CWD84_RS19755	COG0531	amino acid
CWD84_RS19765	COG1215	transferase activity, transferring glycosyl groups
CWD84_RS19770	COG5298	Protein conserved in bacteria
CWD84_RS19775	COG3706	GGDEF domain
CWD84_RS19780	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CWD84_RS19785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWD84_RS19785	COG0551	DNA topoisomerase type I activity
CWD84_RS19790	COG1522	sequence-specific DNA binding
CWD84_RS19795	COG2814	Major facilitator Superfamily
CWD84_RS19805	COG3871	stress protein (general stress protein 26)
CWD84_RS19810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWD84_RS19815	COG1917	Cupin 2, conserved barrel domain protein
CWD84_RS19820	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS19825	COG0318	PFAM AMP-dependent synthetase and ligase
CWD84_RS19830	COG3711	transcriptional antiterminator
CWD84_RS19835	COG4989	oxidoreductase activity
CWD84_RS19840	COG0768	penicillin binding
CWD84_RS19845	COG2329	Antibiotic biosynthesis monooxygenase
CWD84_RS19855	COG2755	lipolytic protein G-D-S-L family
CWD84_RS19860	COG1414	Transcriptional regulator
CWD84_RS19865	COG1984	allophanate hydrolase subunit 2
CWD84_RS19870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CWD84_RS19880	COG1914	H( )-stimulated, divalent metal cation uptake system
CWD84_RS19890	COG0561	phosphatase activity
CWD84_RS19900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWD84_RS19910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWD84_RS19915	COG2213	PTS system mannitol-specific
CWD84_RS19925	COG1349	DNA-binding transcription factor activity
CWD84_RS19930	COG1276	copper resistance
CWD84_RS19930	COG2372	response to copper ion
CWD84_RS19935	COG4549	nuclear export factor GLE1
CWD84_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS19945	COG4975	Glucose uptake
CWD84_RS19950	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS19955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS19960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWD84_RS19965	COG0640	Transcriptional regulator
CWD84_RS19970	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CWD84_RS19975	COG0778	Nitroreductase
CWD84_RS19980	COG1309	transcriptional regulator
CWD84_RS19985	COG2814	Major facilitator Superfamily
CWD84_RS19990	COG4607	ABC-type enterochelin transport system periplasmic component
CWD84_RS19995	COG4604	ABC transporter, ATP-binding protein
CWD84_RS20000	COG4605	iron ion homeostasis
CWD84_RS20005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS20010	COG0527	aspartate kinase activity
CWD84_RS20025	COG0457	Tetratricopeptide repeat
CWD84_RS20030	COG5002	protein histidine kinase activity
CWD84_RS20030	COG3850	Histidine kinase
CWD84_RS20035	COG0745	RESPONSE REGULATOR receiver
CWD84_RS20040	COG0577	efflux transmembrane transporter activity
CWD84_RS20045	COG1136	(ABC) transporter
CWD84_RS20050	COG2079	MmgE PrpD family protein
CWD84_RS20055	COG1473	amidohydrolase
CWD84_RS20060	COG1126	abc transporter atp-binding protein
CWD84_RS20065	COG0765	amino acid transport
CWD84_RS20070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS20075	COG0456	acetyltransferase
CWD84_RS20080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWD84_RS20085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CWD84_RS20095	COG0697	spore germination
CWD84_RS20105	COG5434	Belongs to the glycosyl hydrolase 28 family
CWD84_RS20110	COG3104	oligopeptide transport
CWD84_RS20125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CWD84_RS20130	COG0163	prenyltransferase activity
CWD84_RS20135	COG0583	DNA-binding transcription factor activity
CWD84_RS20140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWD84_RS20145	COG0765	amino acid transport
CWD84_RS20150	COG1126	abc transporter atp-binding protein
CWD84_RS20155	COG2364	Membrane
CWD84_RS20170	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CWD84_RS20175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS20180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS20185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CWD84_RS20190	COG1733	regulation of RNA biosynthetic process
CWD84_RS20195	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CWD84_RS20200	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CWD84_RS20205	COG3209	COG3209 Rhs family protein
CWD84_RS20225	COG1714	RDD family
CWD84_RS20230	COG1063	alcohol dehydrogenase
CWD84_RS20235	COG0523	cobalamin synthesis protein
CWD84_RS20240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CWD84_RS20245	COG2146	nitrite reductase [NAD(P)H] activity
CWD84_RS20250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWD84_RS20250	COG1587	Uroporphyrinogen-III synthase
CWD84_RS20260	COG2508	Transcriptional regulator
CWD84_RS20265	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWD84_RS20270	COG1012	belongs to the aldehyde dehydrogenase family
CWD84_RS20275	COG0506	proline dehydrogenase activity
CWD84_RS20280	COG3541	Predicted nucleotidyltransferase
CWD84_RS20285	COG3458	cephalosporin-C deacetylase activity
CWD84_RS20290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWD84_RS20295	COG2271	Major facilitator Superfamily
CWD84_RS20315	COG3665	Urea carboxylase-associated protein
CWD84_RS20320	COG1113	amino acid transport
CWD84_RS20325	COG3403	YqcI/YcgG family
CWD84_RS20330	COG1280	lysine exporter protein (LysE YggA)
CWD84_RS20335	COG1846	Transcriptional regulator
CWD84_RS20340	COG2814	Major facilitator Superfamily
CWD84_RS20350	COG0366	Alpha amylase catalytic
CWD84_RS20360	COG1288	antiporter activity
CWD84_RS20365	COG1473	amidohydrolase
CWD84_RS20375	COG2113	Glycine betaine
CWD84_RS20380	COG4176	ABC-type proline glycine betaine transport system permease component
CWD84_RS20385	COG0517	IMP dehydrogenase activity
CWD84_RS20385	COG4175	Glycine betaine
CWD84_RS20390	COG0477	Major facilitator Superfamily
CWD84_RS20395	COG3853	Toxic anion resistance protein (TelA)
CWD84_RS20405	COG0861	Integral membrane protein TerC family
CWD84_RS20410	COG2310	stress, protein
CWD84_RS20415	COG2310	stress, protein
CWD84_RS20420	COG2310	stress, protein
CWD84_RS20430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWD84_RS20435	COG1121	(ABC) transporter
CWD84_RS20440	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWD84_RS20445	COG0366	Alpha amylase catalytic
CWD84_RS20460	COG1028	Short-chain dehydrogenase reductase Sdr
CWD84_RS20465	COG0457	Tetratricopeptide repeat
CWD84_RS20470	COG1876	peptidase activity
CWD84_RS20475	COG1595	DNA-templated transcription, initiation
CWD84_RS20480	COG1595	DNA-templated transcription, initiation
CWD84_RS20490	COG0667	Aldo Keto reductase
CWD84_RS20495	COG1405	negative regulation of cell septum assembly
CWD84_RS20495	COG3012	SEC-C Motif Domain Protein
CWD84_RS20505	COG0252	asparaginase activity
CWD84_RS20510	COG1309	transcriptional regulator
CWD84_RS20515	COG0477	Major facilitator Superfamily
CWD84_RS20520	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWD84_RS20525	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CWD84_RS20530	COG0805	protein transport
CWD84_RS20535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWD84_RS20540	COG3540	Alkaline phosphatase
CWD84_RS20550	COG3773	Cell wall hydrolase
CWD84_RS20565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWD84_RS20570	COG2259	Doxx family
CWD84_RS20575	COG0346	lactoylglutathione lyase activity
CWD84_RS20580	COG0778	Nitroreductase
CWD84_RS20585	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWD84_RS20590	COG0784	Response regulator, receiver
CWD84_RS20595	COG4191	Histidine kinase
CWD84_RS20600	COG2066	Belongs to the glutaminase family
CWD84_RS20605	COG1115	amino acid carrier protein
CWD84_RS20610	COG2040	homocysteine
CWD84_RS20615	COG0833	amino acid
CWD84_RS20620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS20625	COG1301	dicarboxylic acid transport
CWD84_RS20640	COG0688	phosphatidylethanolamine metabolic process
CWD84_RS20645	COG0586	Pfam SNARE associated Golgi protein
CWD84_RS20650	COG1183	phosphatidylcholine synthase activity
CWD84_RS20660	COG0371	Dehydrogenase
CWD84_RS20670	COG5444	nuclease activity
CWD84_RS20680	COG3409	Peptidoglycan-binding domain 1 protein
CWD84_RS20690	COG2368	4-hydroxyphenylacetate
CWD84_RS20705	COG2271	Major facilitator Superfamily
CWD84_RS20710	COG0584	glycerophosphoryl diester phosphodiesterase
CWD84_RS20725	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CWD84_RS20730	COG0531	amino acid
CWD84_RS20760	COG1511	domain protein
CWD84_RS20760	COG0842	Transport permease protein
CWD84_RS20770	COG1131	(ABC) transporter
CWD84_RS20775	COG2197	response regulator
CWD84_RS20780	COG4585	Histidine kinase
CWD84_RS20785	COG1011	Hydrolase
CWD84_RS20790	COG1113	amino acid transport
CWD84_RS20795	COG1846	Transcriptional regulator
CWD84_RS20800	COG1380	Effector of murein hydrolase LrgA
CWD84_RS20805	COG1346	cytolysis
CWD84_RS20830	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CWD84_RS20845	COG4856	YbbR-like protein
CWD84_RS20850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CWD84_RS20855	COG5662	AntiSigma factor
CWD84_RS20860	COG1595	DNA-templated transcription, initiation
CWD84_RS20890	COG1683	Conserved Protein
CWD84_RS20895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWD84_RS20905	COG1263	PTS System
CWD84_RS20905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWD84_RS20910	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWD84_RS20915	COG1472	Belongs to the glycosyl hydrolase 3 family
CWD84_RS20920	COG3876	Protein conserved in bacteria
CWD84_RS20925	COG2207	Transcriptional regulator
CWD84_RS20925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS20930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWD84_RS20935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS20940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWD84_RS20945	COG2819	hydrolase of the alpha beta superfamily
CWD84_RS20950	COG0385	Bile acid
CWD84_RS20970	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS20975	COG0738	Major facilitator superfamily
CWD84_RS21035	COG0726	polysaccharide deacetylase
CWD84_RS21040	COG2194	sulfuric ester hydrolase activity
CWD84_RS21050	COG0489	protein tyrosine kinase activity
CWD84_RS21055	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWD84_RS21065	COG2318	DinB family
CWD84_RS21070	COG2226	methyltransferase
CWD84_RS21090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWD84_RS21095	COG1122	ATPase activity
CWD84_RS21100	COG1122	ATPase activity
CWD84_RS21125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWD84_RS21140	COG0024	Methionine aminopeptidase
CWD84_RS21150	COG0201	protein transport
CWD84_RS21165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWD84_RS21260	COG0596	Alpha beta hydrolase
CWD84_RS21285	COG1358	cellular component organization or biogenesis
CWD84_RS21300	COG2813	Specifically methylates the guanine in position
CWD84_RS21325	COG0250	Participates in transcription elongation, termination and antitermination
CWD84_RS21330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWD84_RS21340	COG1595	DNA-templated transcription, initiation
CWD84_RS21345	COG3688	RNA-binding protein containing a PIN domain
CWD84_RS21350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWD84_RS21355	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CWD84_RS21365	COG1045	serine acetyltransferase
CWD84_RS21385	COG4956	integral membrane protein (PIN domain superfamily)
CWD84_RS21390	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CWD84_RS21395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CWD84_RS21400	COG0542	response to heat
CWD84_RS21410	COG3880	PFAM UvrB UvrC protein
CWD84_RS21415	COG4463	regulation of RNA biosynthetic process
CWD84_RS21500	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWD84_RS21505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWD84_RS21510	COG1396	sequence-specific DNA binding
CWD84_RS21515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CWD84_RS21520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWD84_RS21525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CWD84_RS21530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWD84_RS21535	COG0512	Glutamine amidotransferase of anthranilate synthase
CWD84_RS21540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWD84_RS21545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWD84_RS21550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWD84_RS21565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWD84_RS21570	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWD84_RS21575	COG0037	tRNA processing
CWD84_RS21580	COG0515	serine threonine protein kinase
CWD84_RS21585	COG2304	oxidoreductase activity
CWD84_RS21590	COG2208	phosphoserine phosphatase activity
CWD84_RS21605	COG1098	S1 RNA binding domain
CWD84_RS21610	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CWD84_RS21625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWD84_RS21630	COG3956	TIGRFAM MazG family protein
CWD84_RS21635	COG2244	polysaccharide biosynthetic process
CWD84_RS21640	COG2002	toxin-antitoxin pair type II binding
CWD84_RS21645	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWD84_RS21665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWD84_RS21680	COG0251	oxidation-reduction process
CWD84_RS21685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWD84_RS21700	COG4466	Protein conserved in bacteria
CWD84_RS21710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWD84_RS21715	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CWD84_RS21720	COG3584	3D domain protein
CWD84_RS21720	COG3583	domain protein
CWD84_RS21725	COG0084	hydrolase, TatD family'
CWD84_RS21730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWD84_RS21730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWD84_RS21735	COG2002	toxin-antitoxin pair type II binding
CWD84_RS21740	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CWD84_RS21750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWD84_RS21760	COG1774	PSP1 C-terminal conserved region
CWD84_RS21765	COG0470	DNA polymerase III
CWD84_RS21770	COG1728	Protein conserved in bacteria
CWD84_RS21775	COG3870	Protein conserved in bacteria
CWD84_RS21785	COG1982	Orn Lys Arg decarboxylase major
CWD84_RS21790	COG3853	Toxic anion resistance protein (TelA)
CWD84_RS21795	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
CWD84_RS21845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CWD84_RS21850	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWD84_RS21860	COG0590	tRNA wobble adenosine to inosine editing
CWD84_RS21865	COG1335	isochorismatase
CWD84_RS21870	COG3858	chitin binding
CWD84_RS21870	COG1388	LysM domain
CWD84_RS21875	COG1428	Deoxynucleoside kinase
CWD84_RS21880	COG1428	Deoxynucleoside kinase
CWD84_RS21890	COG1929	Belongs to the glycerate kinase type-1 family
CWD84_RS21910	COG1686	Belongs to the peptidase S11 family
CWD84_RS21915	COG0516	GMP reductase activity
CWD84_RS21915	COG0517	IMP dehydrogenase activity
CWD84_RS21950	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWD84_RS21955	COG0187	DNA topoisomerase II activity
CWD84_RS21970	COG2501	S4 domain
CWD84_RS21975	COG0592	DNA-directed DNA polymerase activity