locus-tag	class	description
OM992_RS00010	COG0592	DNA-directed DNA polymerase activity
OM992_RS00015	COG2501	S4 domain
OM992_RS00030	COG0187	DNA topoisomerase II activity
OM992_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OM992_RS00070	COG0516	GMP reductase activity
OM992_RS00070	COG0517	IMP dehydrogenase activity
OM992_RS00075	COG1686	Belongs to the peptidase S11 family
OM992_RS00095	COG1929	Belongs to the glycerate kinase type-1 family
OM992_RS00105	COG1428	Deoxynucleoside kinase
OM992_RS00110	COG1428	Deoxynucleoside kinase
OM992_RS00115	COG1388	LysM domain
OM992_RS00115	COG3858	chitin binding
OM992_RS00120	COG1335	isochorismatase
OM992_RS00125	COG0590	tRNA wobble adenosine to inosine editing
OM992_RS00135	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OM992_RS00140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OM992_RS00190	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OM992_RS00195	COG3853	Toxic anion resistance protein (TelA)
OM992_RS00200	COG1982	Orn Lys Arg decarboxylase major
OM992_RS00210	COG3870	Protein conserved in bacteria
OM992_RS00215	COG1728	Protein conserved in bacteria
OM992_RS00220	COG0470	DNA polymerase III
OM992_RS00225	COG1774	PSP1 C-terminal conserved region
OM992_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OM992_RS00245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OM992_RS00250	COG2002	toxin-antitoxin pair type II binding
OM992_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS00260	COG0084	hydrolase, TatD family'
OM992_RS00265	COG3583	domain protein
OM992_RS00265	COG3584	3D domain protein
OM992_RS00270	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OM992_RS00275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OM992_RS00285	COG4466	Protein conserved in bacteria
OM992_RS00300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OM992_RS00305	COG0251	oxidation-reduction process
OM992_RS00320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OM992_RS00340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OM992_RS00345	COG2002	toxin-antitoxin pair type II binding
OM992_RS00350	COG2244	polysaccharide biosynthetic process
OM992_RS00355	COG3956	TIGRFAM MazG family protein
OM992_RS00360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OM992_RS00375	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OM992_RS00380	COG1098	S1 RNA binding domain
OM992_RS00395	COG2208	phosphoserine phosphatase activity
OM992_RS00400	COG2304	oxidoreductase activity
OM992_RS00405	COG0515	serine threonine protein kinase
OM992_RS00410	COG0037	tRNA processing
OM992_RS00415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OM992_RS00420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OM992_RS00435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM992_RS00440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM992_RS00445	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM992_RS00450	COG0512	Glutamine amidotransferase of anthranilate synthase
OM992_RS00455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM992_RS00460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OM992_RS00465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OM992_RS00470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OM992_RS00475	COG1396	sequence-specific DNA binding
OM992_RS00480	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM992_RS00485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OM992_RS00565	COG4463	regulation of RNA biosynthetic process
OM992_RS00570	COG3880	PFAM UvrB UvrC protein
OM992_RS00580	COG0542	response to heat
OM992_RS00585	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OM992_RS00590	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OM992_RS00595	COG4956	integral membrane protein (PIN domain superfamily)
OM992_RS00615	COG1045	serine acetyltransferase
OM992_RS00625	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OM992_RS00630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM992_RS00635	COG3688	RNA-binding protein containing a PIN domain
OM992_RS00640	COG1595	DNA-templated transcription, initiation
OM992_RS00650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OM992_RS00655	COG0250	Participates in transcription elongation, termination and antitermination
OM992_RS00665	COG0081	regulation of translation
OM992_RS00680	COG2813	Specifically methylates the guanine in position
OM992_RS00695	COG1358	cellular component organization or biogenesis
OM992_RS00720	COG0596	Alpha beta hydrolase
OM992_RS00815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OM992_RS00830	COG0201	protein transport
OM992_RS00840	COG0024	Methionine aminopeptidase
OM992_RS00855	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OM992_RS00880	COG1122	ATPase activity
OM992_RS00885	COG1122	ATPase activity
OM992_RS00890	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OM992_RS00910	COG2226	methyltransferase
OM992_RS00915	COG2318	DinB family
OM992_RS00925	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS00930	COG0489	protein tyrosine kinase activity
OM992_RS00940	COG2194	sulfuric ester hydrolase activity
OM992_RS00945	COG0726	polysaccharide deacetylase
OM992_RS01005	COG0738	Major facilitator superfamily
OM992_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OM992_RS01025	COG0659	secondary active sulfate transmembrane transporter activity
OM992_RS01030	COG0385	Bile acid
OM992_RS01035	COG2819	hydrolase of the alpha beta superfamily
OM992_RS01040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS01045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS01050	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS01055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS01055	COG2207	Transcriptional regulator
OM992_RS01060	COG3876	Protein conserved in bacteria
OM992_RS01065	COG1472	Belongs to the glycosyl hydrolase 3 family
OM992_RS01070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM992_RS01075	COG1263	PTS System
OM992_RS01075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM992_RS01090	COG1683	Conserved Protein
OM992_RS01120	COG1595	DNA-templated transcription, initiation
OM992_RS01125	COG5662	AntiSigma factor
OM992_RS01130	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OM992_RS01135	COG4856	YbbR-like protein
OM992_RS01175	COG1346	cytolysis
OM992_RS01180	COG1380	Effector of murein hydrolase LrgA
OM992_RS01185	COG1846	Transcriptional regulator
OM992_RS01190	COG1113	amino acid transport
OM992_RS01195	COG1011	Hydrolase
OM992_RS01200	COG4585	Histidine kinase
OM992_RS01205	COG2197	response regulator
OM992_RS01210	COG1131	(ABC) transporter
OM992_RS01230	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OM992_RS01250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS01250	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS01250	COG3321	synthase
OM992_RS01250	COG4221	oxidoreductase activity
OM992_RS01255	COG0300	oxidoreductase activity
OM992_RS01255	COG3321	synthase
OM992_RS01255	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS01255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS01255	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS01295	COG0531	amino acid
OM992_RS01300	COG0584	glycerophosphoryl diester phosphodiesterase
OM992_RS01305	COG2271	Major facilitator Superfamily
OM992_RS01315	COG2368	4-hydroxyphenylacetate
OM992_RS01325	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS01340	COG0371	Dehydrogenase
OM992_RS01350	COG1183	phosphatidylcholine synthase activity
OM992_RS01355	COG0586	Pfam SNARE associated Golgi protein
OM992_RS01360	COG0688	phosphatidylethanolamine metabolic process
OM992_RS01375	COG1301	dicarboxylic acid transport
OM992_RS01380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM992_RS01385	COG0833	amino acid
OM992_RS01390	COG2040	homocysteine
OM992_RS01395	COG1115	amino acid carrier protein
OM992_RS01400	COG2066	Belongs to the glutaminase family
OM992_RS01405	COG4191	Histidine kinase
OM992_RS01410	COG0784	Response regulator, receiver
OM992_RS01415	COG3173	Aminoglycoside phosphotransferase
OM992_RS01425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM992_RS01430	COG0778	Nitroreductase
OM992_RS01435	COG0346	lactoylglutathione lyase activity
OM992_RS01440	COG2259	Doxx family
OM992_RS01445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS01455	COG3773	Cell wall hydrolase
OM992_RS01460	COG3540	Alkaline phosphatase
OM992_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM992_RS01470	COG0805	protein transport
OM992_RS01475	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OM992_RS01480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM992_RS01485	COG0477	Major facilitator Superfamily
OM992_RS01490	COG1309	transcriptional regulator
OM992_RS01495	COG0252	asparaginase activity
OM992_RS01500	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OM992_RS01505	COG1405	negative regulation of cell septum assembly
OM992_RS01505	COG3012	SEC-C Motif Domain Protein
OM992_RS01510	COG0667	Aldo Keto reductase
OM992_RS01520	COG1595	DNA-templated transcription, initiation
OM992_RS01525	COG1595	DNA-templated transcription, initiation
OM992_RS01530	COG1876	peptidase activity
OM992_RS01535	COG0457	Tetratricopeptide repeat
OM992_RS01540	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS01545	COG0366	Alpha amylase catalytic
OM992_RS01550	COG0803	Belongs to the bacterial solute-binding protein 9 family
OM992_RS01555	COG1121	(ABC) transporter
OM992_RS01560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OM992_RS01565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS01570	COG2310	stress, protein
OM992_RS01575	COG2310	stress, protein
OM992_RS01580	COG2310	stress, protein
OM992_RS01585	COG0861	Integral membrane protein TerC family
OM992_RS01595	COG3853	Toxic anion resistance protein (TelA)
OM992_RS01600	COG0477	Major facilitator Superfamily
OM992_RS01605	COG4175	Glycine betaine
OM992_RS01605	COG0517	IMP dehydrogenase activity
OM992_RS01610	COG4176	ABC-type proline glycine betaine transport system permease component
OM992_RS01615	COG2113	Glycine betaine
OM992_RS01620	COG1473	amidohydrolase
OM992_RS01625	COG1288	antiporter activity
OM992_RS01635	COG0366	Alpha amylase catalytic
OM992_RS01645	COG2814	Major facilitator Superfamily
OM992_RS01650	COG1846	Transcriptional regulator
OM992_RS01655	COG1280	lysine exporter protein (LysE YggA)
OM992_RS01660	COG3403	YqcI/YcgG family
OM992_RS01665	COG1113	amino acid transport
OM992_RS01670	COG3665	Urea carboxylase-associated protein
OM992_RS01685	COG1082	Xylose isomerase domain protein TIM barrel
OM992_RS01690	COG2271	Major facilitator Superfamily
OM992_RS01695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OM992_RS01700	COG3458	cephalosporin-C deacetylase activity
OM992_RS01705	COG3541	Predicted nucleotidyltransferase
OM992_RS01710	COG0506	proline dehydrogenase activity
OM992_RS01715	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS01720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM992_RS01725	COG2508	Transcriptional regulator
OM992_RS01735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM992_RS01735	COG1587	Uroporphyrinogen-III synthase
OM992_RS01740	COG2146	nitrite reductase [NAD(P)H] activity
OM992_RS01745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OM992_RS01755	COG0523	cobalamin synthesis protein
OM992_RS01760	COG1063	alcohol dehydrogenase
OM992_RS01765	COG1714	RDD family
OM992_RS01785	COG3209	COG3209 Rhs family protein
OM992_RS01790	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OM992_RS01795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
OM992_RS01800	COG1733	regulation of RNA biosynthetic process
OM992_RS01805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS01825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS01830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS01835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OM992_RS01850	COG2364	Membrane
OM992_RS01855	COG1126	abc transporter atp-binding protein
OM992_RS01860	COG0765	amino acid transport
OM992_RS01865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS01870	COG0583	DNA-binding transcription factor activity
OM992_RS01880	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OM992_RS01895	COG3104	oligopeptide transport
OM992_RS01900	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS01910	COG0697	spore germination
OM992_RS01920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OM992_RS01925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS01930	COG0456	acetyltransferase
OM992_RS01935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS01940	COG0765	amino acid transport
OM992_RS01945	COG1126	abc transporter atp-binding protein
OM992_RS01950	COG1473	amidohydrolase
OM992_RS01955	COG2079	MmgE PrpD family protein
OM992_RS01960	COG1136	(ABC) transporter
OM992_RS01965	COG0577	efflux transmembrane transporter activity
OM992_RS01970	COG0745	RESPONSE REGULATOR receiver
OM992_RS01975	COG3850	Histidine kinase
OM992_RS01975	COG5002	protein histidine kinase activity
OM992_RS01980	COG0457	Tetratricopeptide repeat
OM992_RS01995	COG0527	aspartate kinase activity
OM992_RS02000	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS02005	COG4605	iron ion homeostasis
OM992_RS02010	COG4604	ABC transporter, ATP-binding protein
OM992_RS02015	COG4607	ABC-type enterochelin transport system periplasmic component
OM992_RS02020	COG2814	Major facilitator Superfamily
OM992_RS02025	COG1309	transcriptional regulator
OM992_RS02030	COG0778	Nitroreductase
OM992_RS02035	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OM992_RS02040	COG0640	Transcriptional regulator
OM992_RS02045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM992_RS02050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OM992_RS02055	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS02060	COG4975	Glucose uptake
OM992_RS02065	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS02070	COG4549	nuclear export factor GLE1
OM992_RS02075	COG1276	copper resistance
OM992_RS02075	COG2372	response to copper ion
OM992_RS02080	COG1349	DNA-binding transcription factor activity
OM992_RS02090	COG2213	PTS system mannitol-specific
OM992_RS02095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM992_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OM992_RS02115	COG0561	phosphatase activity
OM992_RS02125	COG1914	H( )-stimulated, divalent metal cation uptake system
OM992_RS02135	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OM992_RS02140	COG1984	allophanate hydrolase subunit 2
OM992_RS02145	COG1414	Transcriptional regulator
OM992_RS02150	COG2755	lipolytic protein G-D-S-L family
OM992_RS02160	COG2329	Antibiotic biosynthesis monooxygenase
OM992_RS02165	COG0768	penicillin binding
OM992_RS02170	COG4989	oxidoreductase activity
OM992_RS02175	COG3711	transcriptional antiterminator
OM992_RS02180	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS02190	COG1917	Cupin 2, conserved barrel domain protein
OM992_RS02195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM992_RS02200	COG3871	stress protein (general stress protein 26)
OM992_RS02210	COG2814	Major facilitator Superfamily
OM992_RS02215	COG1522	sequence-specific DNA binding
OM992_RS02220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM992_RS02220	COG0551	DNA topoisomerase type I activity
OM992_RS02225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OM992_RS02230	COG3706	GGDEF domain
OM992_RS02235	COG5298	Protein conserved in bacteria
OM992_RS02240	COG1215	transferase activity, transferring glycosyl groups
OM992_RS02250	COG0531	amino acid
OM992_RS02255	COG0494	nUDIX hydrolase
OM992_RS02260	COG0028	Belongs to the TPP enzyme family
OM992_RS02295	COG1914	H( )-stimulated, divalent metal cation uptake system
OM992_RS02320	COG2217	Heavy metal translocating P-type atpase
OM992_RS02325	COG3729	General stress protein
OM992_RS02330	COG0662	Cupin 2, conserved barrel domain protein
OM992_RS02335	COG2329	Antibiotic biosynthesis monooxygenase
OM992_RS02340	COG3546	catalase activity
OM992_RS02345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OM992_RS02350	COG3290	protein histidine kinase activity
OM992_RS02355	COG4565	transcriptional regulatory protein
OM992_RS02360	COG1301	dicarboxylic acid transport
OM992_RS02365	COG0628	permease
OM992_RS02370	COG1131	(ABC) transporter
OM992_RS02375	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM992_RS02385	COG1960	acyl-CoA dehydrogenase activity
OM992_RS02400	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM992_RS02405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS02415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OM992_RS02420	COG0513	Belongs to the DEAD box helicase family
OM992_RS02425	COG3402	PFAM membrane-flanked domain
OM992_RS02430	COG3428	Bacterial PH domain
OM992_RS02435	COG0705	Rhomboid family
OM992_RS02445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OM992_RS02450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM992_RS02455	COG0864	Transcriptional regulator
OM992_RS02460	COG2337	Toxic component of a toxin-antitoxin (TA) module
OM992_RS02465	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS02470	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS02475	COG2172	sigma factor antagonist activity
OM992_RS02480	COG2208	phosphoserine phosphatase activity
OM992_RS02485	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS02495	COG1191	sigma factor activity
OM992_RS02500	COG2208	phosphoserine phosphatase activity
OM992_RS02505	COG2183	response to ionizing radiation
OM992_RS02555	COG0582	viral genome integration into host DNA
OM992_RS02565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM992_RS02600	COG1959	2 iron, 2 sulfur cluster binding
OM992_RS02620	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM992_RS02635	COG1764	response to oxidative stress
OM992_RS02640	COG1846	Transcriptional regulator
OM992_RS02650	COG1959	2 iron, 2 sulfur cluster binding
OM992_RS02655	COG2910	NAD(P)H-binding
OM992_RS02660	COG3239	Fatty acid desaturase
OM992_RS02665	COG1278	Cold shock
OM992_RS02670	COG1329	Transcriptional regulator
OM992_RS02680	COG2175	clavaminate synthase activity
OM992_RS02695	COG0477	Major facilitator Superfamily
OM992_RS02715	COG0456	acetyltransferase
OM992_RS02715	COG1846	Transcriptional regulator
OM992_RS02720	COG2271	Major facilitator Superfamily
OM992_RS02725	COG3621	Patatin-like phospholipase
OM992_RS02745	COG0277	FAD linked oxidase domain protein
OM992_RS02765	COG0662	Cupin 2, conserved barrel domain protein
OM992_RS02770	COG0456	acetyltransferase
OM992_RS02785	COG1064	alcohol dehydrogenase
OM992_RS02790	COG0789	Transcriptional regulator
OM992_RS02800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM992_RS02815	COG3963	phosphatidate phosphatase activity
OM992_RS02835	COG2814	Major facilitator Superfamily
OM992_RS02840	COG1309	transcriptional regulator
OM992_RS02850	COG5577	PFAM Coat F domain
OM992_RS02860	COG1063	alcohol dehydrogenase
OM992_RS02865	COG5577	PFAM Coat F domain
OM992_RS02875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OM992_RS02880	COG0488	(ABC) transporter
OM992_RS02885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM992_RS02890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS02900	COG2814	Major facilitator Superfamily
OM992_RS02915	COG0730	response to heat
OM992_RS02920	COG0456	acetyltransferase
OM992_RS02925	COG1051	belongs to the nudix hydrolase family
OM992_RS02930	COG0596	Alpha beta hydrolase
OM992_RS02935	COG0473	3-isopropylmalate dehydrogenase activity
OM992_RS02940	COG1802	Transcriptional regulator
OM992_RS02945	COG1819	glycosyl
OM992_RS02960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM992_RS02970	COG1388	LysM domain
OM992_RS02975	COG2814	Major facilitator Superfamily
OM992_RS02980	COG2186	Transcriptional regulator
OM992_RS02985	COG2807	transmembrane transport
OM992_RS02990	COG2076	Multidrug Resistance protein
OM992_RS03000	COG1309	transcriptional regulator
OM992_RS03005	COG0531	amino acid
OM992_RS03015	COG3832	glyoxalase III activity
OM992_RS03020	COG0604	alcohol dehydrogenase
OM992_RS03025	COG2814	Major facilitator Superfamily
OM992_RS03065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OM992_RS03070	COG0802	atpase or kinase
OM992_RS03075	COG1214	PFAM Peptidase M22, glycoprotease
OM992_RS03080	COG0456	acetyltransferase
OM992_RS03085	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OM992_RS03090	COG0488	(ABC) transporter
OM992_RS03105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OM992_RS03110	COG0805	protein transport
OM992_RS03120	COG1266	CAAX protease self-immunity
OM992_RS03140	COG2856	Zn peptidase
OM992_RS03155	COG1396	sequence-specific DNA binding
OM992_RS03220	COG3935	DnaD domain protein
OM992_RS03225	COG1484	DNA-dependent DNA replication
OM992_RS03340	COG1595	DNA-templated transcription, initiation
OM992_RS03365	COG5484	DNA packaging
OM992_RS03495	COG1388	LysM domain
OM992_RS03495	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS03495	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM992_RS03530	COG0457	Tetratricopeptide repeat
OM992_RS03535	COG1063	alcohol dehydrogenase
OM992_RS03540	COG2211	Major facilitator Superfamily
OM992_RS03545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM992_RS03555	COG1842	Phage shock protein A
OM992_RS03560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM992_RS03565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OM992_RS03570	COG4260	virion core protein, lumpy skin disease virus
OM992_RS03575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OM992_RS03575	COG2755	lipolytic protein G-D-S-L family
OM992_RS03585	COG1595	DNA-templated transcription, initiation
OM992_RS03590	COG1063	alcohol dehydrogenase
OM992_RS03595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OM992_RS03600	COG0823	Involved in the tonB-independent uptake of proteins
OM992_RS03615	COG2132	Multicopper oxidase
OM992_RS03620	COG1113	amino acid transport
OM992_RS03630	COG0017	Asparaginyl-tRNA synthetase
OM992_RS03645	COG1181	Belongs to the D-alanine--D-alanine ligase family
OM992_RS03650	COG2175	clavaminate synthase activity
OM992_RS03655	COG1794	racemase activity, acting on amino acids and derivatives
OM992_RS03670	COG0714	Associated with various cellular activities
OM992_RS03675	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
OM992_RS03680	COG1305	Transglutaminase-like
OM992_RS03705	COG2252	PERMEase
OM992_RS03710	COG3064	Membrane
OM992_RS03730	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OM992_RS03735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OM992_RS03740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OM992_RS03745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OM992_RS03750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OM992_RS03765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OM992_RS03775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OM992_RS03780	COG0138	bifunctional purine biosynthesis protein purh
OM992_RS03785	COG0151	Belongs to the GarS family
OM992_RS03795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OM992_RS03800	COG1470	cell adhesion involved in biofilm formation
OM992_RS03805	COG4496	protein, YerC YecD
OM992_RS03810	COG0069	glutamate synthase activity
OM992_RS03820	COG0210	DNA helicase
OM992_RS03830	COG4851	CamS sex pheromone cAM373 precursor
OM992_RS03835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM992_RS03840	COG1285	pathogenesis
OM992_RS03845	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM992_RS03865	COG1309	transcriptional regulator
OM992_RS03870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OM992_RS03875	COG1597	lipid kinase activity
OM992_RS03880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM992_RS03915	COG5444	nuclease activity
OM992_RS03945	COG3546	catalase activity
OM992_RS03950	COG0454	-acetyltransferase
OM992_RS03960	COG2323	membrane
OM992_RS03970	COG2329	Antibiotic biosynthesis monooxygenase
OM992_RS03975	COG0346	lactoylglutathione lyase activity
OM992_RS03980	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS03985	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OM992_RS03990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OM992_RS03995	COG4208	sulfate ABC transporter
OM992_RS04005	COG5583	Uncharacterized small protein (DUF2292)
OM992_RS04010	COG0196	riboflavin kinase activity
OM992_RS04015	COG0670	Belongs to the BI1 family
OM992_RS04020	COG1846	Transcriptional regulator
OM992_RS04025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM992_RS04035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM992_RS04035	COG2124	cytochrome p450
OM992_RS04040	COG1368	sulfuric ester hydrolase activity
OM992_RS04045	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OM992_RS04050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS04055	COG1442	glycosyl transferase family 8
OM992_RS04060	COG1216	Glycosyl transferase, family 2
OM992_RS04065	COG1442	glycosyl transferase family 8
OM992_RS04070	COG2223	nitrite transmembrane transporter activity
OM992_RS04075	COG0531	amino acid
OM992_RS04080	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS04085	COG0840	transmembrane signaling receptor activity
OM992_RS04090	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS04095	COG0463	Glycosyl transferase, family 2
OM992_RS04095	COG0457	Tetratricopeptide repeat
OM992_RS04100	COG0488	(ABC) transporter
OM992_RS04105	COG0789	Transcriptional regulator
OM992_RS04110	COG2814	Major facilitator Superfamily
OM992_RS04115	COG0488	(ABC) transporter
OM992_RS04120	COG0513	Belongs to the DEAD box helicase family
OM992_RS04125	COG0456	acetyltransferase
OM992_RS04130	COG2130	NADP-dependent
OM992_RS04145	COG3866	Pectate lyase
OM992_RS04150	COG0471	metal ion transport
OM992_RS04165	COG3290	protein histidine kinase activity
OM992_RS04170	COG4565	transcriptional regulatory protein
OM992_RS04175	COG3181	Tripartite tricarboxylate transporter family receptor
OM992_RS04180	COG2851	Citrate transporter
OM992_RS04185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS04190	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OM992_RS04200	COG2258	MOSC domain
OM992_RS04220	COG0024	Methionine aminopeptidase
OM992_RS04225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS04225	COG1263	PTS System
OM992_RS04235	COG1368	sulfuric ester hydrolase activity
OM992_RS04245	COG0071	Belongs to the small heat shock protein (HSP20) family
OM992_RS04265	COG0778	Nitroreductase
OM992_RS04280	COG0737	Belongs to the 5'-nucleotidase family
OM992_RS04285	COG0693	protein deglycase activity
OM992_RS04290	COG1609	Transcriptional regulator
OM992_RS04305	COG2814	Major facilitator Superfamily
OM992_RS04315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM992_RS04320	COG4980	gas vesicle protein
OM992_RS04325	COG1295	ribonuclease BN
OM992_RS04330	COG0477	Major facilitator Superfamily
OM992_RS04335	COG0387	Pfam Sodium calcium exchanger
OM992_RS04345	COG0668	transmembrane transport
OM992_RS04350	COG0535	radical SAM domain protein
OM992_RS04360	COG0726	polysaccharide deacetylase
OM992_RS04365	COG2084	Dehydrogenase
OM992_RS04375	COG0598	Magnesium transport protein CorA
OM992_RS04380	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OM992_RS04385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OM992_RS04395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OM992_RS04400	COG4637	Psort location Cytoplasmic, score
OM992_RS04405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM992_RS04410	COG0022	dehydrogenase e1 component
OM992_RS04415	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM992_RS04420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM992_RS04425	COG3284	Transcriptional regulator
OM992_RS04435	COG1486	melibiose metabolic process
OM992_RS04440	COG1737	Transcriptional regulator
OM992_RS04445	COG1263	PTS System
OM992_RS04445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS04450	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS04455	COG1132	(ABC) transporter
OM992_RS04460	COG1132	(ABC) transporter
OM992_RS04465	COG2259	Doxx family
OM992_RS04470	COG2514	catechol 2,3-dioxygenase activity
OM992_RS04480	COG1695	Transcriptional regulator
OM992_RS04485	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM992_RS04490	COG3936	Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OM992_RS04495	COG0574	Belongs to the PEP-utilizing enzyme family
OM992_RS04495	COG3848	Pyruvate phosphate dikinase
OM992_RS04500	COG2732	(Barnase) inhibitor
OM992_RS04510	COG2814	Major facilitator Superfamily
OM992_RS04515	COG1846	Transcriptional regulator
OM992_RS04520	COG0392	lysyltransferase activity
OM992_RS04520	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OM992_RS04525	COG0384	phenazine biosynthesis protein PhzF
OM992_RS04530	COG0778	Nitroreductase
OM992_RS04545	COG1090	epimerase
OM992_RS04560	COG2814	Major facilitator Superfamily
OM992_RS04575	COG3103	Sh3 type 3 domain protein
OM992_RS04580	COG5658	integral membrane protein
OM992_RS04585	COG0596	Alpha beta hydrolase
OM992_RS04590	COG0463	Glycosyl transferase, family 2
OM992_RS04595	COG4485	Bacterial membrane protein, YfhO
OM992_RS04600	COG1988	membrane-bound metal-dependent
OM992_RS04605	COG0582	viral genome integration into host DNA
OM992_RS04645	COG3645	SOS response
OM992_RS04645	COG3646	Phage regulatory protein
OM992_RS04670	COG0305	Participates in initiation and elongation during chromosome replication
OM992_RS04695	COG1595	DNA-templated transcription, initiation
OM992_RS04745	COG0740	serine-type endopeptidase activity
OM992_RS04850	COG0457	Tetratricopeptide repeat
OM992_RS04860	COG1194	a g-specific adenine glycosylase
OM992_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS04890	COG1132	(ABC) transporter
OM992_RS04895	COG4129	membrane
OM992_RS04905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OM992_RS04910	COG0735	belongs to the Fur family
OM992_RS05030	COG3340	Belongs to the peptidase S51 family
OM992_RS05040	COG0277	FAD linked oxidase domain protein
OM992_RS05050	COG4166	transmembrane transport
OM992_RS05055	COG0601	transmembrane transport
OM992_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM992_RS05065	COG0444	Belongs to the ABC transporter superfamily
OM992_RS05070	COG4608	Belongs to the ABC transporter superfamily
OM992_RS05075	COG0753	catalase activity
OM992_RS05085	COG1116	anion transmembrane transporter activity
OM992_RS05090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM992_RS05095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM992_RS05115	COG1476	TRANSCRIPTIONal
OM992_RS05125	COG3382	B3 4 domain protein
OM992_RS05130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OM992_RS05140	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OM992_RS05145	COG0789	Transcriptional regulator
OM992_RS05150	COG1664	Polymer-forming cytoskeletal
OM992_RS05155	COG1664	Polymer-forming cytoskeletal
OM992_RS05160	COG2766	serine protein kinase
OM992_RS05170	COG1846	Transcriptional regulator
OM992_RS05175	COG1566	PFAM secretion protein HlyD family protein
OM992_RS05180	COG2814	Major facilitator Superfamily
OM992_RS05185	COG0655	NAD(P)H dehydrogenase (quinone) activity
OM992_RS05200	COG1725	Transcriptional regulator
OM992_RS05205	COG1131	(ABC) transporter
OM992_RS05210	COG1131	(ABC) transporter
OM992_RS05215	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM992_RS05220	COG1278	Cold shock
OM992_RS05225	COG1464	Belongs to the NlpA lipoprotein family
OM992_RS05230	COG3706	GGDEF domain
OM992_RS05235	COG1823	symporter activity
OM992_RS05255	COG5577	PFAM Coat F domain
OM992_RS05260	COG0737	Belongs to the 5'-nucleotidase family
OM992_RS05260	COG1525	nuclease
OM992_RS05260	COG4085	toxin activity
OM992_RS05265	COG3764	Sortase (surface protein transpeptidase)
OM992_RS05270	COG0564	pseudouridine synthase activity
OM992_RS05280	COG0517	IMP dehydrogenase activity
OM992_RS05285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OM992_RS05290	COG3153	acetyltransferase
OM992_RS05290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM992_RS05295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM992_RS05300	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OM992_RS05305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OM992_RS05315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OM992_RS05320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OM992_RS05325	COG2203	Gaf domain
OM992_RS05325	COG4585	Histidine kinase
OM992_RS05330	COG2197	response regulator
OM992_RS05335	COG0431	NADPH-dependent FMN reductase
OM992_RS05350	COG1388	LysM domain
OM992_RS05350	COG0791	NLP P60 protein
OM992_RS05355	COG1959	2 iron, 2 sulfur cluster binding
OM992_RS05360	COG0668	transmembrane transport
OM992_RS05365	COG2719	SpoVR family
OM992_RS05370	COG1785	Belongs to the alkaline phosphatase family
OM992_RS05375	COG0791	NLP P60 protein
OM992_RS05375	COG1388	LysM domain
OM992_RS05380	COG0583	DNA-binding transcription factor activity
OM992_RS05385	COG0372	Belongs to the citrate synthase family
OM992_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS05395	COG0531	amino acid
OM992_RS05400	COG0733	neurotransmitter:sodium symporter activity
OM992_RS05415	COG1595	DNA-templated transcription, initiation
OM992_RS05420	COG0204	Acyl-transferase
OM992_RS05425	COG1253	flavin adenine dinucleotide binding
OM992_RS05430	COG0789	Transcriptional regulator
OM992_RS05435	COG0436	Aminotransferase
OM992_RS05440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM992_RS05445	COG1253	flavin adenine dinucleotide binding
OM992_RS05450	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM992_RS05455	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OM992_RS05460	COG0584	glycerophosphoryl diester phosphodiesterase
OM992_RS05470	COG0668	transmembrane transport
OM992_RS05475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OM992_RS05480	COG0726	polysaccharide deacetylase
OM992_RS05485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM992_RS05490	COG3226	Transcriptional regulator
OM992_RS05500	COG0589	response to stress
OM992_RS05505	COG1132	(ABC) transporter
OM992_RS05510	COG1132	(ABC) transporter
OM992_RS05515	COG0702	epimerase
OM992_RS05535	COG0189	ligase activity
OM992_RS05540	COG0189	ligase activity
OM992_RS05555	COG4335	DNA alkylation repair
OM992_RS05560	COG0561	phosphatase activity
OM992_RS05565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM992_RS05575	COG0475	glutathione-regulated potassium exporter activity
OM992_RS05580	COG0490	domain, Protein
OM992_RS05590	COG1024	Enoyl-CoA hydratase
OM992_RS05600	COG4152	abc transporter atp-binding protein
OM992_RS05605	COG1668	transmembrane transport
OM992_RS05610	COG0420	3'-5' exonuclease activity
OM992_RS05615	COG4717	serine-type aminopeptidase activity
OM992_RS05630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OM992_RS05665	COG4980	gas vesicle protein
OM992_RS05680	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OM992_RS05685	COG0537	adenosine 5'-monophosphoramidase activity
OM992_RS05690	COG1131	(ABC) transporter
OM992_RS05695	COG4473	ABC transporter
OM992_RS05705	COG1473	amidohydrolase
OM992_RS05710	COG3069	C4-dicarboxylate transmembrane transporter activity
OM992_RS05715	COG2329	Antibiotic biosynthesis monooxygenase
OM992_RS05720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM992_RS05730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OM992_RS05735	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OM992_RS05740	COG1309	transcriptional regulator
OM992_RS05745	COG1511	domain protein
OM992_RS05750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM992_RS05760	COG1363	Peptidase, m42
OM992_RS05765	COG1301	dicarboxylic acid transport
OM992_RS05775	COG1234	tRNA 3'-trailer cleavage
OM992_RS05780	COG0095	Lipoate-protein ligase
OM992_RS05785	COG0702	epimerase
OM992_RS05790	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS05800	COG0501	Belongs to the peptidase M48B family
OM992_RS05805	COG1404	Belongs to the peptidase S8 family
OM992_RS05810	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
OM992_RS05815	COG0406	alpha-ribazole phosphatase activity
OM992_RS05820	COG0183	Belongs to the thiolase family
OM992_RS05825	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS05830	COG1268	BioY protein
OM992_RS05835	COG0840	transmembrane signaling receptor activity
OM992_RS05840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM992_RS05840	COG0723	plastoquinol--plastocyanin reductase activity
OM992_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS05855	COG4903	ComK protein
OM992_RS05860	COG5646	InterPro IPR014922
OM992_RS05885	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM992_RS05900	COG0398	Pfam SNARE associated Golgi protein
OM992_RS05905	COG0681	Belongs to the peptidase S26 family
OM992_RS05910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OM992_RS05915	COG1846	Transcriptional regulator
OM992_RS05920	COG3180	Ammonia monooxygenase
OM992_RS05925	COG2814	Major facilitator Superfamily
OM992_RS05935	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
OM992_RS05940	COG2323	membrane
OM992_RS05955	COG0420	3'-5' exonuclease activity
OM992_RS05960	COG0419	ATPase involved in DNA repair
OM992_RS05965	COG1403	HNH endonuclease
OM992_RS06005	COG0179	Fumarylacetoacetate (FAA) hydrolase
OM992_RS06020	COG0367	asparagine synthase
OM992_RS06025	COG1562	ergosterol biosynthetic process
OM992_RS06030	COG0534	Mate efflux family protein
OM992_RS06035	COG1917	Cupin 2, conserved barrel domain protein
OM992_RS06035	COG2207	Transcriptional regulator
OM992_RS06040	COG2318	DinB family
OM992_RS06045	COG1357	PFAM Pentapeptide repeats (8 copies)
OM992_RS06055	COG0646	methionine synthase
OM992_RS06055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OM992_RS06065	COG2996	Protein conserved in bacteria
OM992_RS06075	COG1307	EDD domain protein, DegV family
OM992_RS06080	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS06100	COG0561	phosphatase activity
OM992_RS06105	COG1073	alpha beta
OM992_RS06110	COG2151	metal-sulfur cluster biosynthetic enzyme
OM992_RS06120	COG0277	FAD linked oxidase domain protein
OM992_RS06125	COG2271	Major facilitator Superfamily
OM992_RS06135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OM992_RS06145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM992_RS06150	COG0505	Belongs to the CarA family
OM992_RS06155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM992_RS06160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OM992_RS06175	COG2267	carboxylic ester hydrolase activity
OM992_RS06185	COG1744	ABC transporter substrate-binding protein PnrA-like
OM992_RS06200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM992_RS06205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OM992_RS06210	COG5504	Zn-dependent protease
OM992_RS06215	COG0444	Belongs to the ABC transporter superfamily
OM992_RS06220	COG4608	Belongs to the ABC transporter superfamily
OM992_RS06230	COG0601	transmembrane transport
OM992_RS06235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM992_RS06245	COG0180	Tryptophanyl-tRNA synthetase
OM992_RS06250	COG4166	transmembrane transport
OM992_RS06255	COG0601	transmembrane transport
OM992_RS06260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM992_RS06265	COG0444	Belongs to the ABC transporter superfamily
OM992_RS06270	COG4608	Belongs to the ABC transporter superfamily
OM992_RS06280	COG0456	acetyltransferase
OM992_RS06285	COG1393	Belongs to the ArsC family
OM992_RS06290	COG0861	Integral membrane protein TerC family
OM992_RS06300	COG4862	establishment of competence for transformation
OM992_RS06305	COG4469	Competence protein
OM992_RS06310	COG1164	Oligoendopeptidase f
OM992_RS06320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM992_RS06325	COG2346	COG2346, Truncated hemoglobins
OM992_RS06330	COG0741	lytic transglycosylase activity
OM992_RS06335	COG4116	CYTH
OM992_RS06345	COG2357	RelA SpoT domain protein
OM992_RS06350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM992_RS06355	COG0564	pseudouridine synthase activity
OM992_RS06365	COG0569	domain protein
OM992_RS06365	COG0475	glutathione-regulated potassium exporter activity
OM992_RS06370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OM992_RS06375	COG0352	thiamine-phosphate diphosphorylase activity
OM992_RS06380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM992_RS06385	COG2104	thiamine diphosphate biosynthetic process
OM992_RS06395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM992_RS06400	COG0351	phosphomethylpyrimidine kinase
OM992_RS06405	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OM992_RS06460	COG0210	DNA helicase
OM992_RS06480	COG1131	(ABC) transporter
OM992_RS06490	COG2153	protein acetylation
OM992_RS06500	COG2382	esterase
OM992_RS06505	COG0626	cystathionine gamma-synthase activity
OM992_RS06510	COG0626	cystathionine gamma-synthase activity
OM992_RS06525	COG5444	nuclease activity
OM992_RS06585	COG2367	Beta-lactamase
OM992_RS06590	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OM992_RS06595	COG2814	Major facilitator Superfamily
OM992_RS06600	COG1846	Transcriptional regulator
OM992_RS06610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OM992_RS06615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OM992_RS06620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OM992_RS06625	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM992_RS06625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM992_RS06630	COG1447	Phosphotransferase system cellobiose-specific component IIA
OM992_RS06635	COG2723	6-phospho-beta-galactosidase activity
OM992_RS06640	COG1349	DNA-binding transcription factor activity
OM992_RS06660	COG1285	pathogenesis
OM992_RS06670	COG2205	protein histidine kinase activity
OM992_RS06680	COG3383	formate dehydrogenase (NAD+) activity
OM992_RS06685	COG2427	Protein of unknown function (DUF1641)
OM992_RS06690	COG2124	cytochrome p450
OM992_RS06695	COG1819	glycosyl
OM992_RS06705	COG1587	Uroporphyrinogen-III synthase
OM992_RS06710	COG0390	transport system, permease component
OM992_RS06715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM992_RS06720	COG0697	spore germination
OM992_RS06725	COG4297	protein containing double-stranded beta helix domain
OM992_RS06735	COG1252	NADH dehydrogenase
OM992_RS06740	COG1609	Transcriptional regulator
OM992_RS06750	COG0730	response to heat
OM992_RS06755	COG2318	DinB family
OM992_RS06760	COG0457	Tetratricopeptide repeat
OM992_RS06770	COG1388	LysM domain
OM992_RS06770	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS06770	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM992_RS06780	COG4195	phage-related replication protein
OM992_RS06785	COG2856	Zn peptidase
OM992_RS06790	COG1396	sequence-specific DNA binding
OM992_RS06800	COG1522	sequence-specific DNA binding
OM992_RS06805	COG1484	DNA-dependent DNA replication
OM992_RS06825	COG1595	DNA-templated transcription, initiation
OM992_RS06830	COG3728	DNA packaging
OM992_RS06830	COG5484	DNA packaging
OM992_RS06835	COG1783	phage Terminase large subunit
OM992_RS06840	COG5518	Phage portal protein
OM992_RS06845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OM992_RS06850	COG4653	Phage capsid family
OM992_RS06900	COG3953	SLT domain
OM992_RS06900	COG3953	SLT domain
OM992_RS06900	COG5412	phage tail tape measure protein
OM992_RS06900	COG5412	phage tail tape measure protein
OM992_RS06900	COG3953	SLT domain
OM992_RS06900	COG5412	phage tail tape measure protein
OM992_RS06905	COG1652	LysM domain
OM992_RS06910	COG4193	domain, Protein
OM992_RS06920	COG3628	GPW Gp25 family protein
OM992_RS06925	COG3299	homolog of phage Mu protein gp47
OM992_RS06930	COG3778	Protein conserved in bacteria
OM992_RS06970	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS06970	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM992_RS06990	COG0306	phosphate transporter
OM992_RS06995	COG1392	Phosphate transport regulator
OM992_RS07000	COG0531	amino acid
OM992_RS07005	COG0346	lactoylglutathione lyase activity
OM992_RS07010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OM992_RS07015	COG0463	Glycosyl transferase, family 2
OM992_RS07025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM992_RS07030	COG0477	Major facilitator Superfamily
OM992_RS07035	COG2362	D-Aminopeptidase
OM992_RS07040	COG0601	transmembrane transport
OM992_RS07045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OM992_RS07050	COG0444	Belongs to the ABC transporter superfamily
OM992_RS07055	COG4166	transmembrane transport
OM992_RS07060	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM992_RS07065	COG4948	Mandelate Racemase Muconate Lactonizing
OM992_RS07070	COG0791	NLP P60 protein
OM992_RS07075	COG4608	Belongs to the ABC transporter superfamily
OM992_RS07080	COG2706	6-phosphogluconolactonase activity
OM992_RS07085	COG1834	amidinotransferase
OM992_RS07090	COG1607	acyl-coa hydrolase
OM992_RS07095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OM992_RS07100	COG2076	Multidrug Resistance protein
OM992_RS07105	COG2076	Multidrug Resistance protein
OM992_RS07110	COG0788	formyltetrahydrofolate deformylase activity
OM992_RS07115	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM992_RS07125	COG1764	response to oxidative stress
OM992_RS07130	COG1846	Transcriptional regulator
OM992_RS07135	COG1764	response to oxidative stress
OM992_RS07150	COG0463	Glycosyl transferase, family 2
OM992_RS07150	COG0457	Tetratricopeptide repeat
OM992_RS07160	COG0590	tRNA wobble adenosine to inosine editing
OM992_RS07165	COG2814	Major facilitator Superfamily
OM992_RS07170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM992_RS07180	COG1404	Belongs to the peptidase S8 family
OM992_RS07185	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS07190	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OM992_RS07195	COG1122	ATPase activity
OM992_RS07200	COG4721	ABC-type cobalt transport system, permease component
OM992_RS07205	COG1388	LysM domain
OM992_RS07205	COG3858	chitin binding
OM992_RS07215	COG2239	Acts as a magnesium transporter
OM992_RS07220	COG0789	Transcriptional regulator
OM992_RS07235	COG1846	Transcriptional regulator
OM992_RS07240	COG0726	polysaccharide deacetylase
OM992_RS07245	COG3285	dna ligase
OM992_RS07245	COG1793	dna ligase
OM992_RS07250	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OM992_RS07255	COG3300	MHYT domain
OM992_RS07255	COG5001	Diguanylate cyclase
OM992_RS07260	COG0586	Pfam SNARE associated Golgi protein
OM992_RS07270	COG1191	sigma factor activity
OM992_RS07295	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OM992_RS07300	COG2323	membrane
OM992_RS07310	COG3594	Acyltransferase
OM992_RS07315	COG5002	protein histidine kinase activity
OM992_RS07320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OM992_RS07340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OM992_RS07345	COG0436	Aminotransferase
OM992_RS07375	COG3852	Histidine kinase
OM992_RS07380	COG1846	Transcriptional regulator
OM992_RS07385	COG1360	Flagellar Motor Protein
OM992_RS07390	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM992_RS07395	COG0542	response to heat
OM992_RS07400	COG3949	Membrane
OM992_RS07415	COG0720	synthase
OM992_RS07420	COG0602	queuosine metabolic process
OM992_RS07480	COG4873	Protein conserved in bacteria
OM992_RS07490	COG3773	Cell wall hydrolase
OM992_RS07495	COG2244	polysaccharide biosynthetic process
OM992_RS07500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS07505	COG2217	Heavy metal translocating P-type atpase
OM992_RS07510	COG0006	proline dipeptidase activity
OM992_RS07520	COG1609	Transcriptional regulator
OM992_RS07525	COG3711	transcriptional antiterminator
OM992_RS07530	COG1263	PTS System
OM992_RS07530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS07530	COG2190	(PTS) system
OM992_RS07535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM992_RS07540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OM992_RS07550	COG1533	DNA photolyase activity
OM992_RS07555	COG0840	transmembrane signaling receptor activity
OM992_RS07560	COG2084	Dehydrogenase
OM992_RS07565	COG2340	Cysteine-rich secretory protein family
OM992_RS07570	COG0768	penicillin binding
OM992_RS07580	COG0436	Aminotransferase
OM992_RS07590	COG0784	Response regulator, receiver
OM992_RS07590	COG0835	chemotaxis
OM992_RS07600	COG2814	Major facilitator Superfamily
OM992_RS07605	COG1376	ErfK ybiS ycfS ynhG family protein
OM992_RS07610	COG1408	metallophosphoesterase
OM992_RS07615	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS07625	COG2200	EAL domain
OM992_RS07630	COG4703	Protein of unknown function (DUF1797)
OM992_RS07635	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
OM992_RS07645	COG0517	IMP dehydrogenase activity
OM992_RS07650	COG0583	DNA-binding transcription factor activity
OM992_RS07655	COG0716	FMN binding
OM992_RS07665	COG0716	FMN binding
OM992_RS07685	COG0668	transmembrane transport
OM992_RS07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS07710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OM992_RS07715	COG0303	'Molybdopterin
OM992_RS07720	COG1763	Mo-molybdopterin cofactor biosynthetic process
OM992_RS07725	COG0314	molybdopterin synthase activity
OM992_RS07730	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OM992_RS07740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OM992_RS07745	COG1136	(ABC) transporter
OM992_RS07750	COG0577	efflux transmembrane transporter activity
OM992_RS07755	COG1349	DNA-binding transcription factor activity
OM992_RS07760	COG1105	Belongs to the carbohydrate kinase PfkB family
OM992_RS07765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM992_RS07765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM992_RS07765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OM992_RS07770	COG0681	Belongs to the peptidase S26 family
OM992_RS07780	COG0488	(ABC) transporter
OM992_RS07785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM992_RS07790	COG2309	aminopeptidase activity
OM992_RS07800	COG1077	Cell shape determining protein MreB Mrl
OM992_RS07805	COG2002	toxin-antitoxin pair type II binding
OM992_RS07810	COG3852	Histidine kinase
OM992_RS07815	COG2105	PFAM AIG2 family protein
OM992_RS07815	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
OM992_RS07820	COG0569	domain protein
OM992_RS07830	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OM992_RS07840	COG0561	phosphatase activity
OM992_RS07845	COG0242	peptide deformylase activity
OM992_RS07855	COG0497	DNA recombination
OM992_RS07860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM992_RS07865	COG0022	dehydrogenase e1 component
OM992_RS07870	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM992_RS07875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM992_RS07880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS07895	COG1982	Orn Lys Arg decarboxylase major
OM992_RS07915	COG0483	inositol monophosphate 1-phosphatase activity
OM992_RS07925	COG3227	Zinc metalloprotease (Elastase)
OM992_RS07940	COG1595	DNA-templated transcription, initiation
OM992_RS07960	COG1217	gtp-binding protein TYPA
OM992_RS07970	COG4896	Protein conserved in bacteria
OM992_RS07980	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OM992_RS07985	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM992_RS07990	COG2066	Belongs to the glutaminase family
OM992_RS08000	COG0772	Belongs to the SEDS family
OM992_RS08005	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OM992_RS08020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM992_RS08020	COG2010	Cytochrome c
OM992_RS08025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM992_RS08030	COG1845	cytochrome c oxidase, subunit III
OM992_RS08035	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OM992_RS08040	COG3336	cytochrome c oxidase
OM992_RS08050	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
OM992_RS08055	COG2340	Cysteine-rich secretory protein family
OM992_RS08070	COG3679	Belongs to the UPF0342 family
OM992_RS08080	COG0742	ribosomal rna small subunit methyltransferase
OM992_RS08090	COG3314	Sporulation integral membrane protein YlbJ
OM992_RS08095	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM992_RS08100	COG3480	Lon protease (S16) C-terminal proteolytic domain
OM992_RS08110	COG1399	metal-binding, possibly nucleic acid-binding protein
OM992_RS08130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OM992_RS08150	COG4839	cell division protein FtsL
OM992_RS08155	COG0768	penicillin binding
OM992_RS08160	COG0768	penicillin binding
OM992_RS08180	COG0772	Belongs to the SEDS family
OM992_RS08195	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OM992_RS08200	COG0849	cell division
OM992_RS08205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OM992_RS08210	COG4412	M6 family metalloprotease domain protein
OM992_RS08210	COG1404	Belongs to the peptidase S8 family
OM992_RS08220	COG1191	sigma factor activity
OM992_RS08225	COG1191	sigma factor activity
OM992_RS08230	COG1119	ATPase activity
OM992_RS08235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM992_RS08240	COG1873	PFAM PRC-barrel domain
OM992_RS08245	COG1496	oxidoreductase activity
OM992_RS08250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OM992_RS08260	COG0762	integral membrane protein
OM992_RS08265	COG2302	S4 RNA-binding domain
OM992_RS08270	COG3599	regulation of cell shape
OM992_RS08275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OM992_RS08280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM992_RS08290	COG0564	pseudouridine synthase activity
OM992_RS08300	COG2233	PERMEase
OM992_RS08310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM992_RS08315	COG0505	Belongs to the CarA family
OM992_RS08320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OM992_RS08335	COG0284	orotidine-5'-phosphate decarboxylase activity
OM992_RS08340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OM992_RS08350	COG0306	phosphate transporter
OM992_RS08365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OM992_RS08370	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
OM992_RS08375	COG1648	precorrin-2 dehydrogenase activity
OM992_RS08390	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OM992_RS08395	COG1561	YicC-like family, N-terminal region
OM992_RS08405	COG0194	GDP metabolic process
OM992_RS08415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM992_RS08420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OM992_RS08425	COG0242	peptide deformylase activity
OM992_RS08435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OM992_RS08435	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OM992_RS08445	COG0631	protein serine/threonine phosphatase activity
OM992_RS08450	COG0515	serine threonine protein kinase
OM992_RS08450	COG2815	serine threonine protein kinase
OM992_RS08460	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OM992_RS08465	COG1564	THIamine pyrophosphokinase
OM992_RS08480	COG1302	Protein conserved in bacteria
OM992_RS08485	COG1461	Dihydroxyacetone kinase
OM992_RS08490	COG1760	l-serine dehydratase
OM992_RS08495	COG1760	l-serine dehydratase
OM992_RS08500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OM992_RS08515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM992_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS08535	COG1196	nuclear chromosome segregation
OM992_RS08540	COG0552	protein localization to endoplasmic reticulum
OM992_RS08555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OM992_RS08565	COG1837	Belongs to the UPF0109 family
OM992_RS08590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OM992_RS08605	COG2257	FlhB HrpN YscU SpaS Family
OM992_RS08615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OM992_RS08620	COG0758	DNA mediated transformation
OM992_RS08625	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OM992_RS08635	COG4974	Belongs to the 'phage' integrase family
OM992_RS08655	COG1815	bacterial-type flagellum-dependent cell motility
OM992_RS08660	COG1558	bacterial-type flagellum-dependent cell motility
OM992_RS08665	COG1677	Flagellar hook-basal body complex protein FliE
OM992_RS08670	COG1766	The M ring may be actively involved in energy transduction
OM992_RS08675	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM992_RS08680	COG1317	bacterial-type flagellum organization
OM992_RS08685	COG1157	protein secretion by the type III secretion system
OM992_RS08690	COG2882	bacterial-type flagellum organization
OM992_RS08695	COG3334	PFAM MgtE intracellular
OM992_RS08700	COG3144	bacterial-type flagellum assembly
OM992_RS08705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OM992_RS08710	COG4786	Flagellar basal body rod
OM992_RS08715	COG1582	Flagellar protein (FlbD)
OM992_RS08720	COG1580	Controls the rotational direction of flagella during chemotaxis
OM992_RS08725	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM992_RS08730	COG1776	CheC inhibitor of MCP methylation
OM992_RS08730	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OM992_RS08735	COG2201	protein-glutamate methylesterase activity
OM992_RS08740	COG3190	flagellar
OM992_RS08745	COG1338	Plays a role in the flagellum-specific transport system
OM992_RS08750	COG1987	bacterial-type flagellum assembly
OM992_RS08755	COG1684	flagellar biosynthetic protein fliR
OM992_RS08760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM992_RS08765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OM992_RS08770	COG1419	protein localization to endoplasmic reticulum
OM992_RS08775	COG0455	bacterial-type flagellum organization
OM992_RS08780	COG2201	protein-glutamate methylesterase activity
OM992_RS08785	COG0643	Histidine kinase
OM992_RS08785	COG2198	Histidine kinase
OM992_RS08790	COG0835	chemotaxis
OM992_RS08795	COG1776	CheC inhibitor of MCP methylation
OM992_RS08805	COG1191	sigma factor activity
OM992_RS08835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OM992_RS08840	COG4589	Belongs to the CDS family
OM992_RS08850	COG0750	zinc metalloprotease
OM992_RS08870	COG0195	Participates in both transcription termination and antitermination
OM992_RS08875	COG2740	Nucleic-acid-binding protein implicated in transcription termination
OM992_RS08880	COG1358	cellular component organization or biogenesis
OM992_RS08890	COG1550	Protein conserved in bacteria
OM992_RS08905	COG0196	riboflavin kinase activity
OM992_RS08920	COG0726	polysaccharide deacetylase
OM992_RS08925	COG0612	Peptidase, M16
OM992_RS08930	COG1873	PFAM PRC-barrel domain
OM992_RS08935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM992_RS08940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OM992_RS08945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OM992_RS08950	COG0527	aspartate kinase activity
OM992_RS08960	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OM992_RS08965	COG0740	serine-type endopeptidase activity
OM992_RS08975	COG1674	ftsk spoiiie
OM992_RS08975	COG4980	gas vesicle protein
OM992_RS08980	COG2188	Transcriptional regulator
OM992_RS08985	COG2814	Major facilitator Superfamily
OM992_RS08990	COG1846	Transcriptional regulator
OM992_RS08995	COG1033	growth of symbiont in host cell
OM992_RS08995	COG2409	Drug exporters of the RND superfamily
OM992_RS09000	COG0612	Peptidase, M16
OM992_RS09005	COG0612	Peptidase, M16
OM992_RS09010	COG0300	oxidoreductase activity
OM992_RS09025	COG1426	Protein conserved in bacteria
OM992_RS09030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OM992_RS09045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OM992_RS09055	COG1692	metallophosphoesterase
OM992_RS09060	COG2359	stage V sporulation protein S
OM992_RS09080	COG4550	Control of competence regulator ComK, YlbF/YmcA
OM992_RS09125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS09130	COG3425	synthase
OM992_RS09135	COG1024	Enoyl-CoA hydratase
OM992_RS09140	COG1024	Enoyl-CoA hydratase
OM992_RS09145	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS09145	COG0300	oxidoreductase activity
OM992_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS09145	COG3321	synthase
OM992_RS09145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09150	COG4221	oxidoreductase activity
OM992_RS09150	COG3321	synthase
OM992_RS09150	COG0300	oxidoreductase activity
OM992_RS09150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS09155	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS09155	COG3321	synthase
OM992_RS09155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS09155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS09155	COG3321	synthase
OM992_RS09160	COG4221	oxidoreductase activity
OM992_RS09160	COG3321	synthase
OM992_RS09160	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS09160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09165	COG3321	synthase
OM992_RS09165	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OM992_RS09165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS09165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OM992_RS09170	COG2124	cytochrome p450
OM992_RS09175	COG3209	COG3209 Rhs family protein
OM992_RS09180	COG3619	membrane
OM992_RS09190	COG1404	Belongs to the peptidase S8 family
OM992_RS09200	COG4195	phage-related replication protein
OM992_RS09205	COG1764	response to oxidative stress
OM992_RS09215	COG2076	Multidrug Resistance protein
OM992_RS09255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM992_RS09260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OM992_RS09265	COG4112	unkown
OM992_RS09270	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS09275	COG0464	growth
OM992_RS09280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OM992_RS09285	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
OM992_RS09290	COG0789	Transcriptional regulator
OM992_RS09295	COG0174	glutamine synthetase
OM992_RS09305	COG2211	Major facilitator Superfamily
OM992_RS09310	COG3507	Belongs to the glycosyl hydrolase 43 family
OM992_RS09325	COG1070	Carbohydrate kinase
OM992_RS09330	COG3848	Pyruvate phosphate dikinase
OM992_RS09330	COG0574	Belongs to the PEP-utilizing enzyme family
OM992_RS09345	COG2378	regulation of single-species biofilm formation
OM992_RS09350	COG2318	DinB family
OM992_RS09355	COG1064	alcohol dehydrogenase
OM992_RS09360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM992_RS09360	COG4451	ribulose bisphosphate carboxylase, small
OM992_RS09380	COG0456	acetyltransferase
OM992_RS09405	COG3397	chitin binding
OM992_RS09425	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS09435	COG0756	dUTP diphosphatase activity
OM992_RS09440	COG4195	phage-related replication protein
OM992_RS09475	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OM992_RS09485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OM992_RS09505	COG0785	Cytochrome C biogenesis protein
OM992_RS09510	COG2201	protein-glutamate methylesterase activity
OM992_RS09515	COG4846	Membrane protein involved in cytochrome C biogenesis
OM992_RS09525	COG0071	Belongs to the small heat shock protein (HSP20) family
OM992_RS09540	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OM992_RS09545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS09565	COG0824	Thioesterase
OM992_RS09575	COG4841	protein insertion into membrane
OM992_RS09585	COG1832	CoA-binding protein
OM992_RS09590	COG0187	DNA topoisomerase II activity
OM992_RS09595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OM992_RS09610	COG1115	amino acid carrier protein
OM992_RS09645	COG3507	Belongs to the glycosyl hydrolase 43 family
OM992_RS09670	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS09675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OM992_RS09680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM992_RS09685	COG2610	gluconate transmembrane transporter activity
OM992_RS09690	COG2124	cytochrome p450
OM992_RS09710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM992_RS09720	COG2246	polysaccharide biosynthetic process
OM992_RS09725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM992_RS09730	COG0586	Pfam SNARE associated Golgi protein
OM992_RS09735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM992_RS09740	COG1024	Enoyl-CoA hydratase
OM992_RS09745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OM992_RS09750	COG0511	ligase activity, forming carbon-carbon bonds
OM992_RS09755	COG0439	Biotin carboxylase
OM992_RS09765	COG1960	acyl-CoA dehydrogenase activity
OM992_RS09770	COG1649	PFAM Uncharacterised BCR, COG1649
OM992_RS09780	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OM992_RS09780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS09790	COG2027	D-alanyl-D-alanine carboxypeptidase
OM992_RS09795	COG2017	converts alpha-aldose to the beta-anomer
OM992_RS09800	COG0534	Mate efflux family protein
OM992_RS09815	COG0582	viral genome integration into host DNA
OM992_RS09820	COG0166	Belongs to the GPI family
OM992_RS09825	COG0405	Gamma-glutamyltransferase
OM992_RS09830	COG2814	Major facilitator Superfamily
OM992_RS09835	COG0640	Transcriptional regulator
OM992_RS09840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OM992_RS09850	COG0604	alcohol dehydrogenase
OM992_RS09855	COG0493	'glutamate synthase
OM992_RS09860	COG0067	glutamate synthase
OM992_RS09860	COG0069	glutamate synthase activity
OM992_RS09860	COG0070	glutamate synthase
OM992_RS09865	COG0583	DNA-binding transcription factor activity
OM992_RS09870	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OM992_RS09885	COG0300	oxidoreductase activity
OM992_RS09890	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OM992_RS09900	COG2814	Major facilitator Superfamily
OM992_RS09905	COG1070	Carbohydrate kinase
OM992_RS09910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM992_RS09915	COG0243	molybdopterin cofactor binding
OM992_RS09950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS09955	COG0662	Cupin 2, conserved barrel domain protein
OM992_RS09955	COG2207	Transcriptional regulator
OM992_RS09960	COG1309	transcriptional regulator
OM992_RS09965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS09975	COG0640	Transcriptional regulator
OM992_RS09980	COG0741	lytic transglycosylase activity
OM992_RS09985	COG2322	membrane
OM992_RS10000	COG1619	proteins homologs of microcin C7 resistance protein MccF
OM992_RS10010	COG1388	LysM domain
OM992_RS10010	COG3584	3D domain protein
OM992_RS10015	COG0514	ATP-dependent DNA helicase (RecQ)
OM992_RS10025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM992_RS10030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM992_RS10045	COG0071	Belongs to the small heat shock protein (HSP20) family
OM992_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS10080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM992_RS10085	COG0733	neurotransmitter:sodium symporter activity
OM992_RS10090	COG0385	Bile acid
OM992_RS10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS10100	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM992_RS10110	COG4548	von Willebrand factor, type A
OM992_RS10115	COG0714	Associated with various cellular activities
OM992_RS10120	COG2032	superoxide dismutase activity
OM992_RS10125	COG0791	NLP P60 protein
OM992_RS10125	COG1388	LysM domain
OM992_RS10130	COG1819	glycosyl
OM992_RS10135	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OM992_RS10140	COG0534	Mate efflux family protein
OM992_RS10145	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS10150	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM992_RS10155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM992_RS10165	COG2962	Rard protein
OM992_RS10185	COG1733	regulation of RNA biosynthetic process
OM992_RS10190	COG0778	Nitroreductase
OM992_RS10195	COG0400	carboxylic ester hydrolase activity
OM992_RS10200	COG0346	lactoylglutathione lyase activity
OM992_RS10210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OM992_RS10220	COG2723	6-phospho-beta-galactosidase activity
OM992_RS10225	COG2188	Transcriptional regulator
OM992_RS10230	COG0793	Belongs to the peptidase S41A family
OM992_RS10230	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS10235	COG2226	methyltransferase
OM992_RS10245	COG1876	peptidase activity
OM992_RS10265	COG0671	phosphoesterase, PA-phosphatase related
OM992_RS10295	COG1509	lysine 2,3-aminomutase activity
OM992_RS10300	COG0456	acetyltransferase
OM992_RS10305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM992_RS10310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OM992_RS10315	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OM992_RS10320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OM992_RS10325	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OM992_RS10335	COG0456	acetyltransferase
OM992_RS10340	COG0463	Glycosyl transferase, family 2
OM992_RS10355	COG4641	Protein conserved in bacteria
OM992_RS10365	COG1086	Polysaccharide biosynthesis protein
OM992_RS10380	COG1846	Transcriptional regulator
OM992_RS10385	COG4698	Protein conserved in bacteria
OM992_RS10390	COG2755	lipolytic protein G-D-S-L family
OM992_RS10395	COG1999	signal sequence binding
OM992_RS10405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OM992_RS10410	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OM992_RS10415	COG1272	protein, Hemolysin III
OM992_RS10420	COG0204	Acyl-transferase
OM992_RS10425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM992_RS10440	COG2521	methyltransferase
OM992_RS10440	COG2136	Putative SAM-dependent methyltransferase
OM992_RS10455	COG1413	lyase activity
OM992_RS10465	COG0386	Belongs to the glutathione peroxidase family
OM992_RS10475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OM992_RS10485	COG1278	Cold shock
OM992_RS10505	COG0328	RNA-DNA hybrid ribonuclease activity
OM992_RS10510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OM992_RS10515	COG0328	RNA-DNA hybrid ribonuclease activity
OM992_RS10525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS10540	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OM992_RS10550	COG1755	Isoprenylcysteine carboxyl methyltransferase
OM992_RS10555	COG3424	synthase
OM992_RS10585	COG1335	isochorismatase
OM992_RS10610	COG3331	DNA recombination
OM992_RS10685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OM992_RS10720	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM992_RS10725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OM992_RS10755	COG0756	dUTP diphosphatase activity
OM992_RS10760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS10800	COG1780	Probably involved in ribonucleotide reductase function
OM992_RS10870	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
OM992_RS10875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OM992_RS10890	COG3584	3D domain protein
OM992_RS10895	COG0587	DNA-directed DNA polymerase activity
OM992_RS10900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM992_RS10905	COG0358	DNA primase activity
OM992_RS10910	COG0305	Participates in initiation and elongation during chromosome replication
OM992_RS10920	COG2887	Belongs to the helicase family. UvrD subfamily
OM992_RS10935	COG3591	Belongs to the peptidase S1B family
OM992_RS10950	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS10950	COG3420	alginic acid biosynthetic process
OM992_RS10955	COG4195	phage-related replication protein
OM992_RS10985	COG2135	peptidase activity
OM992_RS10990	COG1793	dna ligase
OM992_RS11000	COG5484	DNA packaging
OM992_RS11000	COG3728	DNA packaging
OM992_RS11015	COG0756	dUTP diphosphatase activity
OM992_RS11040	COG4474	Belongs to the UPF0398 family
OM992_RS11100	COG3655	Transcriptional regulator
OM992_RS11225	COG3655	Transcriptional regulator
OM992_RS11230	COG3655	Transcriptional regulator
OM992_RS11315	COG0776	regulation of translation
OM992_RS11440	COG0582	viral genome integration into host DNA
OM992_RS11480	COG0739	heme binding
OM992_RS11480	COG0741	lytic transglycosylase activity
OM992_RS11480	COG1196	nuclear chromosome segregation
OM992_RS11490	COG2433	Pfam Transposase IS66
OM992_RS11505	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS11530	COG0457	Tetratricopeptide repeat
OM992_RS11540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM992_RS11575	COG5444	nuclease activity
OM992_RS11580	COG1525	nuclease
OM992_RS11600	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OM992_RS11605	COG1199	ATP-dependent helicase activity
OM992_RS11620	COG0116	Belongs to the methyltransferase superfamily
OM992_RS11650	COG3359	exonuclease
OM992_RS11655	COG1111	helicase
OM992_RS11655	COG1205	dead DEAH box helicase
OM992_RS11660	COG2190	(PTS) system
OM992_RS11665	COG0071	Belongs to the small heat shock protein (HSP20) family
OM992_RS11705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM992_RS11705	COG4499	WXG100 protein secretion system (Wss), protein YukC
OM992_RS11715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OM992_RS11720	COG3935	DnaD domain protein
OM992_RS11730	COG0436	Aminotransferase
OM992_RS11735	COG5353	protein conserved in bacteria
OM992_RS11745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OM992_RS11745	COG1199	ATP-dependent helicase activity
OM992_RS11765	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
OM992_RS11765	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
OM992_RS11775	COG0438	transferase activity, transferring glycosyl groups
OM992_RS11780	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OM992_RS11795	COG1694	Mazg nucleotide pyrophosphohydrolase
OM992_RS11800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS11805	COG2140	Oxalate decarboxylase
OM992_RS11815	COG4347	Protein of unknown function (DUF1405)
OM992_RS11820	COG2010	Cytochrome c
OM992_RS11820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM992_RS11825	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OM992_RS11830	COG0723	plastoquinol--plastocyanin reductase activity
OM992_RS11845	COG0457	Tetratricopeptide repeat
OM992_RS11855	COG0287	Prephenate dehydrogenase
OM992_RS11890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM992_RS11895	COG4401	Chorismate mutase type I
OM992_RS11910	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OM992_RS11915	COG0105	UTP biosynthetic process
OM992_RS11920	COG0142	geranyltranstransferase activity
OM992_RS11930	COG0142	geranyltranstransferase activity
OM992_RS11945	COG0776	regulation of translation
OM992_RS11950	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OM992_RS11990	COG0539	negative regulation of cytoplasmic translation
OM992_RS12005	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
OM992_RS12010	COG2959	enzyme of heme biosynthesis
OM992_RS12015	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS12015	COG3773	Cell wall hydrolase
OM992_RS12020	COG2339	peptidase activity
OM992_RS12025	COG0492	ferredoxin-NADP+ reductase activity
OM992_RS12030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OM992_RS12035	COG4862	establishment of competence for transformation
OM992_RS12040	COG1408	metallophosphoesterase
OM992_RS12050	COG1388	LysM domain
OM992_RS12055	COG1266	CAAX protease self-immunity
OM992_RS12060	COG0514	ATP-dependent DNA helicase (RecQ)
OM992_RS12065	COG4955	Helix-turn-helix domain
OM992_RS12070	COG1141	Ferredoxin
OM992_RS12075	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OM992_RS12080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OM992_RS12090	COG1595	DNA-templated transcription, initiation
OM992_RS12095	COG5002	protein histidine kinase activity
OM992_RS12100	COG0745	RESPONSE REGULATOR receiver
OM992_RS12105	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM992_RS12110	COG1333	cytochrome c biogenesis protein
OM992_RS12115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS12120	COG1187	pseudouridine synthase activity
OM992_RS12125	COG0700	Nucleoside recognition
OM992_RS12130	COG2715	membrane protein required for spore maturation
OM992_RS12135	COG1686	Belongs to the peptidase S11 family
OM992_RS12160	COG1547	Domain of unknown function (DUF309)
OM992_RS12165	COG0456	acetyltransferase
OM992_RS12180	COG0307	riboflavin synthase, alpha
OM992_RS12185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM992_RS12185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OM992_RS12195	COG0681	Belongs to the peptidase S26 family
OM992_RS12205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OM992_RS12210	COG4086	secreted protein
OM992_RS12215	COG0019	diaminopimelate decarboxylase activity
OM992_RS12220	COG0697	spore germination
OM992_RS12235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OM992_RS12255	COG1191	sigma factor activity
OM992_RS12265	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS12270	COG1686	Belongs to the peptidase S11 family
OM992_RS12275	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OM992_RS12280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OM992_RS12285	COG4974	Belongs to the 'phage' integrase family
OM992_RS12295	COG0735	belongs to the Fur family
OM992_RS12300	COG1300	Membrane
OM992_RS12315	COG0281	malic enzyme
OM992_RS12320	COG1757	Na H antiporter
OM992_RS12325	COG1027	Aspartate ammonia-lyase
OM992_RS12330	COG0252	asparaginase activity
OM992_RS12335	COG1396	sequence-specific DNA binding
OM992_RS12340	COG1379	DNA repair
OM992_RS12345	COG0494	nUDIX hydrolase
OM992_RS12355	COG0667	Aldo Keto reductase
OM992_RS12365	COG1073	alpha beta
OM992_RS12375	COG4918	Iron-sulphur cluster biosynthesis
OM992_RS12380	COG0456	acetyltransferase
OM992_RS12380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OM992_RS12390	COG0456	acetyltransferase
OM992_RS12395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OM992_RS12410	COG0628	permease
OM992_RS12420	COG0346	lactoylglutathione lyase activity
OM992_RS12430	COG3048	D-serine ammonia-lyase activity
OM992_RS12435	COG0300	oxidoreductase activity
OM992_RS12440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS12445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM992_RS12450	COG1024	Enoyl-CoA hydratase
OM992_RS12455	COG3425	synthase
OM992_RS12460	COG2124	cytochrome p450
OM992_RS12465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS12465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS12465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12465	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12465	COG3321	synthase
OM992_RS12470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS12470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS12470	COG3321	synthase
OM992_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12475	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS12475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12475	COG3321	synthase
OM992_RS12475	COG0300	oxidoreductase activity
OM992_RS12480	COG3321	synthase
OM992_RS12480	COG0300	oxidoreductase activity
OM992_RS12480	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS12480	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12485	COG3321	synthase
OM992_RS12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS12485	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12490	COG3321	synthase
OM992_RS12490	COG0300	oxidoreductase activity
OM992_RS12490	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS12490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12495	COG3321	synthase
OM992_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS12495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OM992_RS12495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OM992_RS12500	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS12505	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS12520	COG2070	2-Nitropropane dioxygenase
OM992_RS12520	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OM992_RS12525	COG0250	Participates in transcription elongation, termination and antitermination
OM992_RS12535	COG0596	Alpha beta hydrolase
OM992_RS12550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OM992_RS12555	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OM992_RS12570	COG0706	membrane insertase activity
OM992_RS12575	COG2195	Cleaves the N-terminal amino acid of tripeptides
OM992_RS12580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OM992_RS12585	COG0346	lactoylglutathione lyase activity
OM992_RS12595	COG1376	ErfK ybiS ycfS ynhG family protein
OM992_RS12600	COG4129	membrane
OM992_RS12605	COG1126	abc transporter atp-binding protein
OM992_RS12610	COG0765	amino acid transport
OM992_RS12615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS12625	COG1597	lipid kinase activity
OM992_RS12630	COG0508	dehydrogenase complex catalyzes the overall conversion of
OM992_RS12635	COG0022	dehydrogenase e1 component
OM992_RS12640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OM992_RS12645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OM992_RS12650	COG3426	butyrate kinase activity
OM992_RS12655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OM992_RS12660	COG0280	phosphate acetyltransferase
OM992_RS12665	COG3829	transcription factor binding
OM992_RS12665	COG3290	protein histidine kinase activity
OM992_RS12675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OM992_RS12680	COG2079	MmgE PrpD family protein
OM992_RS12685	COG0372	Belongs to the citrate synthase family
OM992_RS12690	COG1960	acyl-CoA dehydrogenase activity
OM992_RS12695	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM992_RS12700	COG0183	Belongs to the thiolase family
OM992_RS12705	COG0584	glycerophosphoryl diester phosphodiesterase
OM992_RS12710	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS12735	COG1902	pentaerythritol trinitrate reductase activity
OM992_RS12750	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OM992_RS12755	COG0745	RESPONSE REGULATOR receiver
OM992_RS12760	COG0750	zinc metalloprotease
OM992_RS12765	COG0497	DNA recombination
OM992_RS12775	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OM992_RS12785	COG0142	geranyltranstransferase activity
OM992_RS12795	COG1570	exodeoxyribonuclease VII activity
OM992_RS12810	COG1302	Protein conserved in bacteria
OM992_RS12815	COG0439	Biotin carboxylase
OM992_RS12820	COG0511	ligase activity, forming carbon-carbon bonds
OM992_RS12860	COG3854	ATPases associated with a variety of cellular activities
OM992_RS12875	COG0006	proline dipeptidase activity
OM992_RS12885	COG3872	metal-dependent enzyme
OM992_RS12895	COG1752	Esterase of the alpha-beta hydrolase superfamily
OM992_RS12910	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM992_RS12930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM992_RS12945	COG1396	sequence-specific DNA binding
OM992_RS12955	COG0681	Belongs to the peptidase S26 family
OM992_RS12980	COG4940	Competence protein ComGF
OM992_RS12990	COG4970	Tfp pilus assembly protein FimT
OM992_RS12995	COG4537	Required for transformation and DNA binding
OM992_RS13000	COG1459	type II secretion system
OM992_RS13005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OM992_RS13010	COG0598	Magnesium transport protein CorA
OM992_RS13015	COG1253	flavin adenine dinucleotide binding
OM992_RS13020	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS13030	COG1393	Belongs to the ArsC family
OM992_RS13040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS13050	COG0011	TIGRFAM Protein of
OM992_RS13060	COG2866	Carboxypeptidase
OM992_RS13065	COG1940	carbohydrate kinase activity
OM992_RS13070	COG4483	Protein conserved in bacteria
OM992_RS13075	COG1757	Na H antiporter
OM992_RS13085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OM992_RS13100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM992_RS13105	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM992_RS13110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OM992_RS13115	COG0581	inorganic phosphate transmembrane transporter activity
OM992_RS13120	COG0573	inorganic phosphate transmembrane transporter activity
OM992_RS13125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OM992_RS13130	COG0768	penicillin binding
OM992_RS13135	COG0477	Major facilitator Superfamily
OM992_RS13140	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OM992_RS13145	COG2839	Protein conserved in bacteria
OM992_RS13150	COG5521	maltodextrose utilization protein MalA
OM992_RS13155	COG1388	LysM domain
OM992_RS13165	COG4709	membrane
OM992_RS13170	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
OM992_RS13175	COG0735	belongs to the Fur family
OM992_RS13180	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS13195	COG0513	Belongs to the DEAD box helicase family
OM992_RS13210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OM992_RS13215	COG2384	SAM-dependent methyltransferase
OM992_RS13220	COG2010	Cytochrome c
OM992_RS13225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OM992_RS13230	COG0358	DNA primase activity
OM992_RS13245	COG0517	IMP dehydrogenase activity
OM992_RS13250	COG0751	glycine-tRNA ligase activity
OM992_RS13270	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OM992_RS13275	COG0295	cytidine deaminase activity
OM992_RS13280	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OM992_RS13290	COG1480	7TM receptor with intracellular HD hydrolase
OM992_RS13295	COG1702	phosphate starvation-inducible protein PhoH
OM992_RS13300	COG0561	phosphatase activity
OM992_RS13315	COG4864	UPF0365 protein
OM992_RS13320	COG1030	water channel activity
OM992_RS13325	COG1610	YqeY-like protein
OM992_RS13335	COG1283	sodium-dependent phosphate transmembrane transporter activity
OM992_RS13340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OM992_RS13345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OM992_RS13375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OM992_RS13390	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS13420	COG0658	competence protein
OM992_RS13420	COG2333	competence protein COMEC
OM992_RS13425	COG2131	deaminase
OM992_RS13430	COG1555	photosystem II stabilization
OM992_RS13430	COG1596	polysaccharide export
OM992_RS13435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OM992_RS13440	COG2226	methyltransferase
OM992_RS13445	COG0799	negative regulation of ribosome biogenesis
OM992_RS13450	COG1713	HD superfamily hydrolase involved in NAD metabolism
OM992_RS13460	COG1534	Rna-binding protein
OM992_RS13465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OM992_RS13470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OM992_RS13475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
OM992_RS13485	COG2755	lipolytic protein G-D-S-L family
OM992_RS13505	COG0398	Pfam SNARE associated Golgi protein
OM992_RS13525	COG1733	regulation of RNA biosynthetic process
OM992_RS13530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OM992_RS13545	COG0656	L-ascorbic acid biosynthetic process
OM992_RS13575	COG0563	adenylate kinase activity
OM992_RS13580	COG2814	Major facilitator Superfamily
OM992_RS13590	COG2318	DinB family
OM992_RS13600	COG0561	phosphatase activity
OM992_RS13605	COG0561	phosphatase activity
OM992_RS13620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OM992_RS13625	COG2814	Major facilitator Superfamily
OM992_RS13630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM992_RS13630	COG2124	cytochrome p450
OM992_RS13635	COG1309	transcriptional regulator
OM992_RS13640	COG2226	methyltransferase
OM992_RS13655	COG2116	formate transmembrane transporter activity
OM992_RS13660	COG5609	conserved protein (DUF2294)
OM992_RS13665	COG3383	formate dehydrogenase (NAD+) activity
OM992_RS13670	COG2427	Protein of unknown function (DUF1641)
OM992_RS13680	COG0626	cystathionine gamma-synthase activity
OM992_RS13685	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM992_RS13710	COG0768	penicillin binding
OM992_RS13725	COG0826	peptidase U32
OM992_RS13730	COG0826	peptidase U32
OM992_RS13735	COG4122	O-methyltransferase activity
OM992_RS13740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OM992_RS13755	COG4472	Bacterial protein of unknown function (DUF965)
OM992_RS13765	COG0628	permease
OM992_RS13770	COG1126	abc transporter atp-binding protein
OM992_RS13775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS13780	COG0765	amino acid transport
OM992_RS13785	COG0765	amino acid transport
OM992_RS13800	COG3881	PFAM PRC-barrel domain
OM992_RS13805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OM992_RS13810	COG0457	Tetratricopeptide repeat
OM992_RS13820	COG1104	cysteine desulfurase activity
OM992_RS13825	COG1959	2 iron, 2 sulfur cluster binding
OM992_RS13830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OM992_RS13835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OM992_RS13860	COG4991	sh3 domain protein
OM992_RS13860	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS13860	COG3103	Sh3 type 3 domain protein
OM992_RS13865	COG1490	D-aminoacyl-tRNA deacylase activity
OM992_RS13870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OM992_RS13880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OM992_RS13880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
OM992_RS13885	COG5416	Lipopolysaccharide assembly protein A domain
OM992_RS13890	COG0490	domain, Protein
OM992_RS13895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM992_RS13895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OM992_RS13905	COG2244	polysaccharide biosynthetic process
OM992_RS13910	COG2323	membrane
OM992_RS13920	COG1862	Preprotein translocase
OM992_RS13960	COG1388	LysM domain
OM992_RS13970	COG0157	Belongs to the NadC ModD family
OM992_RS13975	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OM992_RS13980	COG1104	cysteine desulfurase activity
OM992_RS13985	COG1827	regulation of RNA biosynthetic process
OM992_RS13990	COG0077	Prephenate dehydratase
OM992_RS14005	COG3290	protein histidine kinase activity
OM992_RS14010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OM992_RS14015	COG2868	ribosomal protein
OM992_RS14025	COG1994	Peptidase M50
OM992_RS14030	COG0739	heme binding
OM992_RS14035	COG2894	cell division
OM992_RS14045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OM992_RS14055	COG1077	Cell shape determining protein MreB Mrl
OM992_RS14070	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM992_RS14070	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS14070	COG1388	LysM domain
OM992_RS14075	COG4824	toxin secretion phage lysis holin
OM992_RS14095	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS14100	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM992_RS14115	COG3953	SLT domain
OM992_RS14115	COG5412	phage tail tape measure protein
OM992_RS14230	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS14230	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS14280	COG1396	sequence-specific DNA binding
OM992_RS14310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OM992_RS14315	COG0285	dihydrofolate synthase activity
OM992_RS14320	COG0525	valine-tRNA ligase activity
OM992_RS14330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM992_RS14335	COG1388	LysM domain
OM992_RS14345	COG0113	porphobilinogen synthase activity
OM992_RS14350	COG1587	Uroporphyrinogen-III synthase
OM992_RS14360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OM992_RS14380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OM992_RS14385	COG1067	ATP-dependent peptidase activity
OM992_RS14385	COG0470	DNA polymerase III
OM992_RS14400	COG1477	protein flavinylation
OM992_RS14400	COG0457	Tetratricopeptide repeat
OM992_RS14415	COG0473	3-isopropylmalate dehydrogenase activity
OM992_RS14430	COG0440	acetolactate synthase activity
OM992_RS14435	COG0028	Belongs to the TPP enzyme family
OM992_RS14490	COG0622	Phosphoesterase
OM992_RS14495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OM992_RS14505	COG5401	PFAM Sporulation and spore germination
OM992_RS14515	COG1846	Transcriptional regulator
OM992_RS14520	COG2197	response regulator
OM992_RS14525	COG0824	Thioesterase
OM992_RS14530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OM992_RS14535	COG1053	succinate dehydrogenase
OM992_RS14540	COG2009	succinate dehydrogenase
OM992_RS14545	COG1719	4-vinyl reductase, 4VR
OM992_RS14550	COG0527	aspartate kinase activity
OM992_RS14560	COG3118	belongs to the thioredoxin family
OM992_RS14565	COG3534	alpha-L-arabinofuranosidase
OM992_RS14570	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OM992_RS14575	COG2086	electron transfer activity
OM992_RS14580	COG1024	Enoyl-CoA hydratase
OM992_RS14585	COG1309	transcriptional regulator
OM992_RS14590	COG0318	PFAM AMP-dependent synthetase and ligase
OM992_RS14600	COG3766	membrane
OM992_RS14610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OM992_RS14610	COG1796	DNA polymerase
OM992_RS14615	COG1286	toxin biosynthetic process
OM992_RS14630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS14630	COG0072	phenylalanine-tRNA ligase activity
OM992_RS14635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OM992_RS14640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OM992_RS14650	COG3835	regulator
OM992_RS14655	COG0277	FAD linked oxidase domain protein
OM992_RS14660	COG0247	lactate metabolic process
OM992_RS14665	COG1966	Carbon starvation protein
OM992_RS14670	COG3534	alpha-L-arabinofuranosidase
OM992_RS14675	COG0395	ABC-type sugar transport system, permease component
OM992_RS14680	COG1175	transmembrane transport
OM992_RS14685	COG1653	transport
OM992_RS14695	COG0647	UMP catabolic process
OM992_RS14700	COG0235	Class ii aldolase
OM992_RS14705	COG1069	ribulokinase activity
OM992_RS14710	COG2160	L-arabinose isomerase activity
OM992_RS14715	COG3507	Belongs to the glycosyl hydrolase 43 family
OM992_RS14720	COG1363	Peptidase, m42
OM992_RS14730	COG3326	Membrane
OM992_RS14745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OM992_RS14750	COG1346	cytolysis
OM992_RS14760	COG3279	Response regulator of the LytR AlgR family
OM992_RS14765	COG3275	phosphorelay sensor kinase activity
OM992_RS14770	COG1011	Hydrolase
OM992_RS14785	COG0398	Pfam SNARE associated Golgi protein
OM992_RS14790	COG1484	DNA-dependent DNA replication
OM992_RS14795	COG3611	Membrane attachment protein
OM992_RS14810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM992_RS14815	COG1733	regulation of RNA biosynthetic process
OM992_RS14820	COG2814	Major facilitator Superfamily
OM992_RS14825	COG0656	L-ascorbic acid biosynthetic process
OM992_RS14830	COG0237	dephospho-CoA kinase activity
OM992_RS14835	COG1971	Probably functions as a manganese efflux pump
OM992_RS14840	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OM992_RS14845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS14845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS14850	COG5002	protein histidine kinase activity
OM992_RS14855	COG0745	RESPONSE REGULATOR receiver
OM992_RS14865	COG0538	isocitrate dehydrogenase activity
OM992_RS14870	COG0372	Belongs to the citrate synthase family
OM992_RS14900	COG0628	permease
OM992_RS14905	COG3030	protein affecting phage T7 exclusion by the F plasmid
OM992_RS14910	COG0469	pyruvate kinase activity
OM992_RS14930	COG0281	malic enzyme
OM992_RS14935	COG0587	DNA-directed DNA polymerase activity
OM992_RS14955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OM992_RS14965	COG4109	DRTGG domain
OM992_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS14995	COG0521	Mo-molybdopterin cofactor biosynthetic process
OM992_RS15005	COG0827	DNA restriction-modification system
OM992_RS15010	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OM992_RS15015	COG3874	Sporulation protein YtfJ
OM992_RS15025	COG1714	RDD family
OM992_RS15030	COG0616	signal peptide processing
OM992_RS15035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OM992_RS15040	COG1574	metal-dependent hydrolase with the TIM-barrel fold
OM992_RS15045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM992_RS15060	COG1104	cysteine desulfurase activity
OM992_RS15065	COG1114	Component of the transport system for branched-chain amino acids
OM992_RS15075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OM992_RS15080	COG1309	transcriptional regulator
OM992_RS15085	COG1956	GAF domain-containing protein
OM992_RS15090	COG2199	diguanylate cyclase activity
OM992_RS15090	COG2203	Gaf domain
OM992_RS15105	COG4282	regulation of fungal-type cell wall biogenesis
OM992_RS15115	COG1017	nitric oxide dioxygenase activity
OM992_RS15115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OM992_RS15125	COG0693	protein deglycase activity
OM992_RS15145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OM992_RS15150	COG1378	Sugar-specific transcriptional regulator TrmB
OM992_RS15175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OM992_RS15180	COG0454	-acetyltransferase
OM992_RS15185	COG0517	IMP dehydrogenase activity
OM992_RS15190	COG0123	including yeast histone deacetylase and acetoin utilization protein
OM992_RS15195	COG1360	Flagellar Motor Protein
OM992_RS15200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OM992_RS15205	COG1609	Transcriptional regulator
OM992_RS15210	COG1605	Chorismate mutase
OM992_RS15210	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
OM992_RS15215	COG3118	belongs to the thioredoxin family
OM992_RS15220	COG4980	gas vesicle protein
OM992_RS15225	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OM992_RS15235	COG1674	ftsk spoiiie
OM992_RS15240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS15260	COG1363	Peptidase, m42
OM992_RS15265	COG5584	Small secreted protein
OM992_RS15270	COG0281	malic enzyme
OM992_RS15275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OM992_RS15290	COG0510	thiamine kinase activity
OM992_RS15295	COG1597	lipid kinase activity
OM992_RS15305	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OM992_RS15310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OM992_RS15315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM992_RS15320	COG2252	PERMEase
OM992_RS15325	COG4473	ABC transporter
OM992_RS15330	COG1131	(ABC) transporter
OM992_RS15335	COG1349	DNA-binding transcription factor activity
OM992_RS15340	COG1187	pseudouridine synthase activity
OM992_RS15345	COG2244	polysaccharide biosynthetic process
OM992_RS15350	COG2081	HI0933 family
OM992_RS15355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OM992_RS15365	COG1609	Transcriptional regulator
OM992_RS15370	COG1653	transport
OM992_RS15375	COG1175	transmembrane transport
OM992_RS15380	COG0395	ABC-type sugar transport system, permease component
OM992_RS15385	COG1486	melibiose metabolic process
OM992_RS15395	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OM992_RS15410	COG1366	Belongs to the anti-sigma-factor antagonist family
OM992_RS15410	COG2202	Pas domain
OM992_RS15415	COG2814	Major facilitator Superfamily
OM992_RS15420	COG5522	Integral membrane protein (intg_mem_TP0381)
OM992_RS15425	COG0577	efflux transmembrane transporter activity
OM992_RS15430	COG1136	(ABC) transporter
OM992_RS15435	COG2205	protein histidine kinase activity
OM992_RS15440	COG0745	RESPONSE REGULATOR receiver
OM992_RS15445	COG0577	efflux transmembrane transporter activity
OM992_RS15450	COG1136	(ABC) transporter
OM992_RS15470	COG1131	(ABC) transporter
OM992_RS15475	COG1725	Transcriptional regulator
OM992_RS15490	COG1242	4 iron, 4 sulfur cluster binding
OM992_RS15495	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
OM992_RS15515	COG2267	carboxylic ester hydrolase activity
OM992_RS15520	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OM992_RS15525	COG1113	amino acid transport
OM992_RS15530	COG0367	asparagine synthase
OM992_RS15550	COG1506	peptidase
OM992_RS15555	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OM992_RS15560	COG1116	anion transmembrane transporter activity
OM992_RS15565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OM992_RS15570	COG0494	nUDIX hydrolase
OM992_RS15575	COG4824	toxin secretion phage lysis holin
OM992_RS15580	COG0783	Belongs to the Dps family
OM992_RS15605	COG0288	reversible hydration of carbon dioxide
OM992_RS15615	COG1271	oxidase subunit
OM992_RS15620	COG1294	oxidase, subunit
OM992_RS15630	COG4948	Mandelate Racemase Muconate Lactonizing
OM992_RS15640	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OM992_RS15645	COG0596	Alpha beta hydrolase
OM992_RS15655	COG1169	isochorismate synthase
OM992_RS15660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OM992_RS15665	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OM992_RS15790	COG3859	Proton-coupled thiamine transporter YuaJ
OM992_RS15795	COG2268	Band 7 protein
OM992_RS15800	COG1585	Membrane protein implicated in regulation of membrane protease activity
OM992_RS15815	COG1454	alcohol dehydrogenase
OM992_RS15820	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS15825	COG1510	regulation of RNA biosynthetic process
OM992_RS15835	COG0569	domain protein
OM992_RS15840	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM992_RS15845	COG1017	nitric oxide dioxygenase activity
OM992_RS15845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OM992_RS15885	COG0628	permease
OM992_RS15890	COG0673	inositol 2-dehydrogenase activity
OM992_RS15895	COG0693	protein deglycase activity
OM992_RS15900	COG0840	transmembrane signaling receptor activity
OM992_RS15905	COG0840	transmembrane signaling receptor activity
OM992_RS15910	COG0840	transmembrane signaling receptor activity
OM992_RS15915	COG0840	transmembrane signaling receptor activity
OM992_RS15930	COG2070	2-Nitropropane dioxygenase
OM992_RS15935	COG0432	Pfam Uncharacterised protein family UPF0047
OM992_RS15940	COG0366	Alpha amylase catalytic
OM992_RS15945	COG1253	flavin adenine dinucleotide binding
OM992_RS15950	COG2738	Putative neutral zinc metallopeptidase
OM992_RS15965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OM992_RS15990	COG1335	isochorismatase
OM992_RS15995	COG1979	alcohol dehydrogenase
OM992_RS16000	COG1979	alcohol dehydrogenase
OM992_RS16005	COG2155	Conserved Protein
OM992_RS16010	COG1098	S1 RNA binding domain
OM992_RS16015	COG0436	Aminotransferase
OM992_RS16020	COG1522	sequence-specific DNA binding
OM992_RS16025	COG2267	carboxylic ester hydrolase activity
OM992_RS16035	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OM992_RS16040	COG2205	protein histidine kinase activity
OM992_RS16050	COG5018	Exonuclease
OM992_RS16055	COG2814	Major facilitator Superfamily
OM992_RS16060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM992_RS16065	COG3011	Protein conserved in bacteria
OM992_RS16075	COG3290	protein histidine kinase activity
OM992_RS16080	COG4565	transcriptional regulatory protein
OM992_RS16085	COG1744	ABC transporter substrate-binding protein PnrA-like
OM992_RS16090	COG3845	ABC transporter
OM992_RS16095	COG4603	Belongs to the binding-protein-dependent transport system permease family
OM992_RS16100	COG1079	Belongs to the binding-protein-dependent transport system permease family
OM992_RS16110	COG2111	Na H antiporter
OM992_RS16110	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OM992_RS16115	COG2111	Na H antiporter
OM992_RS16120	COG1006	Multisubunit Na H antiporter MnhC subunit
OM992_RS16125	COG0651	ATP synthesis coupled electron transport
OM992_RS16130	COG1863	multisubunit Na H antiporter MnhE subunit
OM992_RS16135	COG2212	antiporter activity
OM992_RS16140	COG1320	monovalent cation:proton antiporter activity
OM992_RS16145	COG2050	protein possibly involved in aromatic compounds catabolism
OM992_RS16150	COG2197	response regulator
OM992_RS16155	COG4585	Histidine kinase
OM992_RS16165	COG0142	geranyltranstransferase activity
OM992_RS16180	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OM992_RS16185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OM992_RS16190	COG1335	isochorismatase
OM992_RS16195	COG5506	Protein of unknown function (DUF1694)
OM992_RS16210	COG0628	permease
OM992_RS16220	COG1418	mRNA catabolic process
OM992_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS16235	COG1511	domain protein
OM992_RS16240	COG1674	ftsk spoiiie
OM992_RS16240	COG0433	COG0433 Predicted ATPase
OM992_RS16245	COG4499	WXG100 protein secretion system (Wss), protein YukC
OM992_RS16250	COG5417	Belongs to the EsaB family
OM992_RS16255	COG4842	Belongs to the WXG100 family
OM992_RS16260	COG2508	Transcriptional regulator
OM992_RS16260	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OM992_RS16265	COG0686	Belongs to the AlaDH PNT family
OM992_RS16270	COG5634	Uncharacterized conserved protein (DUF2278)
OM992_RS16275	COG3251	PFAM MbtH domain protein
OM992_RS16280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OM992_RS16285	COG1535	isochorismatase
OM992_RS16285	COG3433	isochorismatase activity
OM992_RS16290	COG1021	2,3-dihydroxybenzoate-AMP ligase
OM992_RS16295	COG1169	isochorismate synthase
OM992_RS16300	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS16305	COG2819	hydrolase of the alpha beta superfamily
OM992_RS16310	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OM992_RS16315	COG1268	BioY protein
OM992_RS16320	COG2056	Na+-H+ antiporter family
OM992_RS16330	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
OM992_RS16335	COG3584	3D domain protein
OM992_RS16350	COG1252	NADH dehydrogenase
OM992_RS16380	COG1131	(ABC) transporter
OM992_RS16405	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
OM992_RS16435	COG5632	N-Acetylmuramoyl-L-alanine amidase
OM992_RS16435	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS16435	COG1388	LysM domain
OM992_RS16460	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS16475	COG3953	SLT domain
OM992_RS16475	COG5280	Phage tail tape measure protein TP901
OM992_RS16520	COG0740	serine-type endopeptidase activity
OM992_RS16625	COG4974	Belongs to the 'phage' integrase family
OM992_RS16630	COG0316	Belongs to the HesB IscA family
OM992_RS16640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM992_RS16650	COG1252	NADH dehydrogenase
OM992_RS16655	COG4837	Protein of unknown function (DUF1462)
OM992_RS16660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OM992_RS16665	COG0823	Involved in the tonB-independent uptake of proteins
OM992_RS16665	COG1506	peptidase
OM992_RS16665	COG4946	Tricorn protease homolog
OM992_RS16675	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OM992_RS16680	COG0460	homoserine dehydrogenase
OM992_RS16685	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OM992_RS16690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OM992_RS16695	COG0647	UMP catabolic process
OM992_RS16700	COG2445	Protein of unknown function DUF86
OM992_RS16705	COG4470	Protein conserved in bacteria
OM992_RS16715	COG0739	heme binding
OM992_RS16725	COG0737	Belongs to the 5'-nucleotidase family
OM992_RS16730	COG0730	response to heat
OM992_RS16735	COG1801	Protein of unknown function DUF72
OM992_RS16745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OM992_RS16750	COG2508	Transcriptional regulator
OM992_RS16755	COG2233	PERMEase
OM992_RS16760	COG2233	PERMEase
OM992_RS16765	COG3195	allantoin biosynthetic process
OM992_RS16765	COG3648	Uricase
OM992_RS16770	COG2351	hydroxyisourate hydrolase activity
OM992_RS16775	COG1794	racemase activity, acting on amino acids and derivatives
OM992_RS16780	COG2080	2 iron, 2 sulfur cluster binding
OM992_RS16785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OM992_RS16790	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OM992_RS16795	COG2068	MobA-Related Protein
OM992_RS16800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM992_RS16805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OM992_RS16810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OM992_RS16815	COG2356	endonuclease I
OM992_RS16830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM992_RS16845	COG0072	phenylalanine-tRNA ligase activity
OM992_RS16845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OM992_RS16860	COG0527	aspartate kinase activity
OM992_RS16865	COG3842	ATPase activity
OM992_RS16870	COG2188	Transcriptional regulator
OM992_RS16875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM992_RS16880	COG0395	ABC-type sugar transport system, permease component
OM992_RS16885	COG1175	transmembrane transport
OM992_RS16890	COG1653	transport
OM992_RS16895	COG2222	sugar isomerase
OM992_RS16900	COG0789	Transcriptional regulator
OM992_RS16925	COG0322	excinuclease ABC activity
OM992_RS16930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OM992_RS16950	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS16975	COG4824	toxin secretion phage lysis holin
OM992_RS16995	COG5434	Belongs to the glycosyl hydrolase 28 family
OM992_RS17000	COG1705	Flagellar rod assembly protein muramidase FlgJ
OM992_RS17010	COG5412	phage tail tape measure protein
OM992_RS17010	COG3953	SLT domain
OM992_RS17115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS17115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OM992_RS17170	COG1396	sequence-specific DNA binding
OM992_RS17180	COG4974	Belongs to the 'phage' integrase family
OM992_RS17185	COG0719	Fe-S assembly protein
OM992_RS17190	COG0822	iron-sulfur transferase activity
OM992_RS17195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OM992_RS17200	COG0719	Fe-S assembly protein
OM992_RS17205	COG0396	ATPase activity
OM992_RS17215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OM992_RS17220	COG1464	Belongs to the NlpA lipoprotein family
OM992_RS17225	COG2011	ABC-type metal ion transport system permease component
OM992_RS17230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OM992_RS17240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OM992_RS17245	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OM992_RS17260	COG1393	Belongs to the ArsC family
OM992_RS17265	COG1960	acyl-CoA dehydrogenase activity
OM992_RS17270	COG0183	Belongs to the thiolase family
OM992_RS17275	COG1024	Enoyl-CoA hydratase
OM992_RS17275	COG1250	3-hydroxyacyl-CoA dehydrogenase
OM992_RS17290	COG0477	Major facilitator Superfamily
OM992_RS17300	COG5577	PFAM Coat F domain
OM992_RS17305	COG1846	Transcriptional regulator
OM992_RS17310	COG0477	Major facilitator Superfamily
OM992_RS17320	COG0583	DNA-binding transcription factor activity
OM992_RS17340	COG1120	ATPase activity
OM992_RS17355	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS17360	COG0783	Belongs to the Dps family
OM992_RS17365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM992_RS17370	COG0745	RESPONSE REGULATOR receiver
OM992_RS17375	COG2205	protein histidine kinase activity
OM992_RS17375	COG2770	Histidine kinase
OM992_RS17385	COG1309	transcriptional regulator
OM992_RS17390	COG0114	fumarate hydratase activity
OM992_RS17400	COG0697	spore germination
OM992_RS17405	COG0814	amino acid
OM992_RS17415	COG2197	response regulator
OM992_RS17420	COG4585	Histidine kinase
OM992_RS17425	COG4758	membrane
OM992_RS17430	COG3595	metallopeptidase activity
OM992_RS17435	COG1842	Phage shock protein A
OM992_RS17440	COG4758	membrane
OM992_RS17445	COG2814	Major facilitator Superfamily
OM992_RS17450	COG2096	Adenosyltransferase
OM992_RS17455	COG1120	ATPase activity
OM992_RS17460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS17465	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS17470	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS17475	COG3386	PFAM SMP-30 Gluconolaconase
OM992_RS17480	COG2205	protein histidine kinase activity
OM992_RS17485	COG0745	RESPONSE REGULATOR receiver
OM992_RS17495	COG1191	sigma factor activity
OM992_RS17505	COG2140	Oxalate decarboxylase
OM992_RS17515	COG1120	ATPase activity
OM992_RS17520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS17525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS17530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS17535	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OM992_RS17540	COG0531	amino acid
OM992_RS17550	COG1988	membrane-bound metal-dependent
OM992_RS17555	COG1368	sulfuric ester hydrolase activity
OM992_RS17560	COG1910	domain protein
OM992_RS17565	COG0725	ABC transporter, periplasmic molybdate-binding protein
OM992_RS17570	COG4149	molybdate abc transporter
OM992_RS17575	COG2197	response regulator
OM992_RS17585	COG1131	(ABC) transporter
OM992_RS17595	COG0842	Transport permease protein
OM992_RS17600	COG0656	L-ascorbic acid biosynthetic process
OM992_RS17620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OM992_RS17625	COG3973	AAA domain
OM992_RS17630	COG2860	membrane
OM992_RS17640	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OM992_RS17645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OM992_RS17650	COG2217	Heavy metal translocating P-type atpase
OM992_RS17655	COG2217	Heavy metal translocating P-type atpase
OM992_RS17660	COG2608	mercury ion transmembrane transporter activity
OM992_RS17665	COG1937	Protein conserved in bacteria
OM992_RS17670	COG0673	inositol 2-dehydrogenase activity
OM992_RS17685	COG2814	Major facilitator Superfamily
OM992_RS17700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS17705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OM992_RS17710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS17715	COG1126	abc transporter atp-binding protein
OM992_RS17720	COG0765	amino acid transport
OM992_RS17725	COG0765	amino acid transport
OM992_RS17730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS17735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OM992_RS17740	COG0454	-acetyltransferase
OM992_RS17745	COG0583	DNA-binding transcription factor activity
OM992_RS17750	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS17755	COG2732	(Barnase) inhibitor
OM992_RS17770	COG0557	exoribonuclease II activity
OM992_RS17775	COG1647	Serine aminopeptidase, S33
OM992_RS17780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OM992_RS17785	COG1476	TRANSCRIPTIONal
OM992_RS17790	COG1396	sequence-specific DNA binding
OM992_RS17795	COG1396	sequence-specific DNA binding
OM992_RS17800	COG1733	regulation of RNA biosynthetic process
OM992_RS17825	COG1131	(ABC) transporter
OM992_RS17830	COG1174	glycine betaine transport
OM992_RS17835	COG1732	Glycine betaine
OM992_RS17840	COG1174	glycine betaine transport
OM992_RS17845	COG0517	IMP dehydrogenase activity
OM992_RS17845	COG1125	glycine betaine transport
OM992_RS17850	COG1510	regulation of RNA biosynthetic process
OM992_RS17855	COG1174	glycine betaine transport
OM992_RS17860	COG1732	Glycine betaine
OM992_RS17865	COG1174	glycine betaine transport
OM992_RS17870	COG0517	IMP dehydrogenase activity
OM992_RS17870	COG1125	glycine betaine transport
OM992_RS17875	COG1510	regulation of RNA biosynthetic process
OM992_RS17880	COG2095	MarC family integral membrane protein
OM992_RS17885	COG3064	Membrane
OM992_RS17890	COG4640	response to antibiotic
OM992_RS17895	COG0456	acetyltransferase
OM992_RS17915	COG0126	phosphoglycerate kinase activity
OM992_RS17920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OM992_RS17925	COG2390	Transcriptional regulator
OM992_RS17930	COG2814	Major facilitator Superfamily
OM992_RS17935	COG1609	Transcriptional regulator
OM992_RS17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS17950	COG0583	DNA-binding transcription factor activity
OM992_RS17955	COG0697	spore germination
OM992_RS17960	COG1113	amino acid transport
OM992_RS17970	COG1737	Transcriptional regulator
OM992_RS17975	COG1070	Carbohydrate kinase
OM992_RS18000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM992_RS18005	COG2186	Transcriptional regulator
OM992_RS18010	COG1620	l-lactate permease
OM992_RS18015	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OM992_RS18025	COG5039	Polysaccharide pyruvyl transferase
OM992_RS18030	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OM992_RS18035	COG0110	maltose O-acetyltransferase activity
OM992_RS18040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OM992_RS18045	COG2244	polysaccharide biosynthetic process
OM992_RS18050	COG1216	Glycosyl transferase, family 2
OM992_RS18055	COG5039	Polysaccharide pyruvyl transferase
OM992_RS18060	COG1216	Glycosyl transferase, family 2
OM992_RS18070	COG0438	transferase activity, transferring glycosyl groups
OM992_RS18075	COG1215	transferase activity, transferring glycosyl groups
OM992_RS18080	COG0438	transferase activity, transferring glycosyl groups
OM992_RS18085	COG1086	Polysaccharide biosynthesis protein
OM992_RS18090	COG0489	protein tyrosine kinase activity
OM992_RS18095	COG3944	biosynthesis protein
OM992_RS18100	COG1396	sequence-specific DNA binding
OM992_RS18105	COG2272	Belongs to the type-B carboxylesterase lipase family
OM992_RS18115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OM992_RS18120	COG2364	Membrane
OM992_RS18125	COG0456	acetyltransferase
OM992_RS18130	COG3479	Phenolic acid decarboxylase
OM992_RS18205	COG2223	nitrite transmembrane transporter activity
OM992_RS18210	COG1609	Transcriptional regulator
OM992_RS18220	COG0583	DNA-binding transcription factor activity
OM992_RS18225	COG2828	Protein conserved in bacteria
OM992_RS18230	COG0477	Major facilitator Superfamily
OM992_RS18230	COG2814	Major facilitator Superfamily
OM992_RS18240	COG1611	Belongs to the LOG family
OM992_RS18245	COG1694	Mazg nucleotide pyrophosphohydrolase
OM992_RS18255	COG0288	reversible hydration of carbon dioxide
OM992_RS18260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OM992_RS18265	COG4290	ribonuclease
OM992_RS18270	COG2162	N-hydroxyarylamine O-acetyltransferase activity
OM992_RS18275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM992_RS18285	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OM992_RS18295	COG1051	belongs to the nudix hydrolase family
OM992_RS18300	COG0492	ferredoxin-NADP+ reductase activity
OM992_RS18305	COG0791	NLP P60 protein
OM992_RS18305	COG3883	PFAM NLP P60 protein
OM992_RS18315	COG0457	Tetratricopeptide repeat
OM992_RS18320	COG5002	protein histidine kinase activity
OM992_RS18325	COG0745	RESPONSE REGULATOR receiver
OM992_RS18335	COG1132	(ABC) transporter
OM992_RS18340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OM992_RS18340	COG0140	phosphoribosyl-ATP diphosphatase activity
OM992_RS18365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OM992_RS18380	COG4990	cell redox homeostasis
OM992_RS18385	COG0110	maltose O-acetyltransferase activity
OM992_RS18405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OM992_RS18415	COG2188	Transcriptional regulator
OM992_RS18420	COG1309	transcriptional regulator
OM992_RS18425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OM992_RS18430	COG1950	PFAM Membrane protein of
OM992_RS18435	COG1983	PspC domain protein
OM992_RS18440	COG3595	metallopeptidase activity
OM992_RS18455	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OM992_RS18465	COG4897	Protein conserved in bacteria
OM992_RS18470	COG3848	Pyruvate phosphate dikinase
OM992_RS18470	COG0574	Belongs to the PEP-utilizing enzyme family
OM992_RS18475	COG1309	transcriptional regulator
OM992_RS18480	COG2814	Major facilitator Superfamily
OM992_RS18485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM992_RS18495	COG0793	Belongs to the peptidase S41A family
OM992_RS18495	COG3409	Peptidoglycan-binding domain 1 protein
OM992_RS18500	COG3420	alginic acid biosynthetic process
OM992_RS18505	COG2177	Part of the ABC transporter FtsEX involved in
OM992_RS18510	COG2884	Cell division ATP-binding protein ftsE
OM992_RS18515	COG2010	Cytochrome c
OM992_RS18520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS18535	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OM992_RS18550	COG1516	flagellar protein fliS
OM992_RS18555	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OM992_RS18560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM992_RS18580	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OM992_RS18585	COG1256	bacterial-type flagellum assembly
OM992_RS18585	COG4786	Flagellar basal body rod
OM992_RS18590	COG3418	PFAM FlgN family protein
OM992_RS18595	COG2747	anti-sigma28 factor FlgM
OM992_RS18605	COG1040	competence protein
OM992_RS18615	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OM992_RS18620	COG1307	EDD domain protein, DegV family
OM992_RS18625	COG2197	response regulator
OM992_RS18630	COG4585	Histidine kinase
OM992_RS18635	COG1739	Uncharacterized protein family UPF0029
OM992_RS18640	COG1316	TRANSCRIPTIONal
OM992_RS18645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OM992_RS18650	COG0438	transferase activity, transferring glycosyl groups
OM992_RS18655	COG1215	transferase activity, transferring glycosyl groups
OM992_RS18660	COG3206	protein involved in exopolysaccharide biosynthesis
OM992_RS18665	COG3307	-O-antigen
OM992_RS18670	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OM992_RS18675	COG0438	transferase activity, transferring glycosyl groups
OM992_RS18675	COG0297	glycogen (starch) synthase activity
OM992_RS18680	COG2244	polysaccharide biosynthetic process
OM992_RS18690	COG2247	cell wall binding repeat
OM992_RS18690	COG0860	N-Acetylmuramoyl-L-alanine amidase
OM992_RS18695	COG2385	sporulation resulting in formation of a cellular spore
OM992_RS18695	COG2247	cell wall binding repeat
OM992_RS18705	COG1316	TRANSCRIPTIONal
OM992_RS18710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OM992_RS18715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OM992_RS18720	COG1134	teichoic acid transport
OM992_RS18725	COG1682	transport, permease protein
OM992_RS18730	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OM992_RS18740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OM992_RS18745	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
OM992_RS18750	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OM992_RS18755	COG4193	domain, Protein
OM992_RS18760	COG1482	cell wall glycoprotein biosynthetic process
OM992_RS18765	COG0697	spore germination
OM992_RS18770	COG0814	amino acid
OM992_RS18780	COG0463	Glycosyl transferase, family 2
OM992_RS18785	COG2814	Major facilitator Superfamily
OM992_RS18790	COG1316	TRANSCRIPTIONal
OM992_RS18795	COG0561	phosphatase activity
OM992_RS18800	COG2433	Pfam Transposase IS66
OM992_RS18805	COG0791	NLP P60 protein
OM992_RS18815	COG2843	Capsule synthesis protein
OM992_RS18825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OM992_RS18835	COG1609	Transcriptional regulator
OM992_RS18840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OM992_RS18850	COG1129	ABC transporter
OM992_RS18855	COG1172	Belongs to the binding-protein-dependent transport system permease family
OM992_RS18860	COG1879	ABC-type sugar transport system periplasmic component
OM992_RS18865	COG3103	Sh3 type 3 domain protein
OM992_RS18870	COG2249	NAD(P)H dehydrogenase (quinone) activity
OM992_RS18875	COG3527	Alpha-acetolactate decarboxylase
OM992_RS18880	COG0028	Belongs to the TPP enzyme family
OM992_RS18885	COG0583	DNA-binding transcription factor activity
OM992_RS18890	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OM992_RS18905	COG5337	Spore coat protein CotH
OM992_RS18915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OM992_RS18925	COG0405	Gamma-glutamyltransferase
OM992_RS18930	COG1522	sequence-specific DNA binding
OM992_RS18935	COG2059	Chromate
OM992_RS18940	COG2059	Chromate
OM992_RS18950	COG0655	NAD(P)H dehydrogenase (quinone) activity
OM992_RS18955	COG0583	DNA-binding transcription factor activity
OM992_RS18970	COG5444	nuclease activity
OM992_RS18985	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OM992_RS18990	COG4464	protein tyrosine phosphatase activity
OM992_RS18995	COG0489	protein tyrosine kinase activity
OM992_RS19000	COG3944	biosynthesis protein
OM992_RS19010	COG4715	Zinc finger, swim domain protein
OM992_RS19015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OM992_RS19020	COG0561	phosphatase activity
OM992_RS19025	COG1349	DNA-binding transcription factor activity
OM992_RS19030	COG0629	single-stranded DNA binding
OM992_RS19055	COG0457	Tetratricopeptide repeat
OM992_RS19060	COG4786	Flagellar basal body rod
OM992_RS19065	COG4786	Flagellar basal body rod
OM992_RS19070	COG1077	Cell shape determining protein MreB Mrl
OM992_RS19075	COG1609	Transcriptional regulator
OM992_RS19080	COG1846	Transcriptional regulator
OM992_RS19085	COG2814	Major facilitator Superfamily
OM992_RS19090	COG1953	Uracil, thiamine, allantoin
OM992_RS19095	COG0477	Major facilitator Superfamily
OM992_RS19100	COG1335	isochorismatase
OM992_RS19105	COG0004	ammonium transporteR
OM992_RS19110	COG0347	Belongs to the P(II) protein family
OM992_RS19115	COG0772	Belongs to the SEDS family
OM992_RS19120	COG0671	phosphoesterase, PA-phosphatase related
OM992_RS19135	COG0739	heme binding
OM992_RS19140	COG1247	-acetyltransferase
OM992_RS19155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM992_RS19165	COG0726	polysaccharide deacetylase
OM992_RS19170	COG1959	2 iron, 2 sulfur cluster binding
OM992_RS19185	COG0831	urea catabolic process
OM992_RS19190	COG3237	CsbD-like
OM992_RS19195	COG1994	Peptidase M50
OM992_RS19200	COG0457	Tetratricopeptide repeat
OM992_RS19210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OM992_RS19220	COG2304	oxidoreductase activity
OM992_RS19225	COG2304	oxidoreductase activity
OM992_RS19230	COG2385	sporulation resulting in formation of a cellular spore
OM992_RS19235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM992_RS19245	COG4836	Membrane
OM992_RS19315	COG0698	ribose 5-phosphate isomerase
OM992_RS19320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OM992_RS19330	COG0009	L-threonylcarbamoyladenylate synthase
OM992_RS19335	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OM992_RS19355	COG2890	protein-(glutamine-N5) methyltransferase activity
OM992_RS19360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OM992_RS19365	COG0346	lactoylglutathione lyase activity
OM992_RS19370	COG0789	Transcriptional regulator
OM992_RS19375	COG0679	Auxin Efflux Carrier
OM992_RS19380	COG0281	malic enzyme
OM992_RS19395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OM992_RS19405	COG1494	fructose-1,6-bisphosphatase
OM992_RS19410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OM992_RS19420	COG0191	fructose-bisphosphate aldolase activity
OM992_RS19425	COG2204	response regulator
OM992_RS19430	COG4821	SIS domain
OM992_RS19445	COG2181	nitrate reductase activity
OM992_RS19445	COG0247	lactate metabolic process
OM992_RS19450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM992_RS19465	COG1132	(ABC) transporter
OM992_RS19470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OM992_RS19480	COG2181	nitrate reductase activity
OM992_RS19485	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
OM992_RS19490	COG1140	nitrate reductase beta subunit
OM992_RS19495	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OM992_RS19500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM992_RS19510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OM992_RS19515	COG2223	nitrite transmembrane transporter activity
OM992_RS19525	COG4506	Protein conserved in bacteria
OM992_RS19535	COG3391	amine dehydrogenase activity
OM992_RS19540	COG3391	amine dehydrogenase activity
OM992_RS19545	COG0457	Tetratricopeptide repeat
OM992_RS19555	COG0010	Belongs to the arginase family
OM992_RS19560	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OM992_RS19565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OM992_RS19580	COG1994	Peptidase M50
OM992_RS19585	COG1942	4-Oxalocrotonate Tautomerase
OM992_RS19590	COG1846	Transcriptional regulator
OM992_RS19595	COG0531	amino acid
OM992_RS19600	COG3465	dGTPase activity
OM992_RS19605	COG1078	dGTPase activity
OM992_RS19620	COG1695	Transcriptional regulator
OM992_RS19630	COG1131	(ABC) transporter
OM992_RS19635	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
OM992_RS19665	COG0583	DNA-binding transcription factor activity
OM992_RS19670	COG2855	membrane
OM992_RS19675	COG0280	phosphate acetyltransferase
OM992_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS19695	COG2814	Major facilitator Superfamily
OM992_RS19700	COG2814	Major facilitator Superfamily
OM992_RS19705	COG0833	amino acid
OM992_RS19710	COG4187	Peptidase family M20/M25/M40
OM992_RS19715	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS19720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OM992_RS19725	COG2205	protein histidine kinase activity
OM992_RS19730	COG0745	RESPONSE REGULATOR receiver
OM992_RS19745	COG1131	(ABC) transporter
OM992_RS19750	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
OM992_RS19755	COG1091	dTDP-4-dehydrorhamnose reductase activity
OM992_RS19760	COG1088	dTDP-glucose 4,6-dehydratase activity
OM992_RS19765	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OM992_RS19770	COG3980	spore coat polysaccharide biosynthesis protein
OM992_RS19775	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OM992_RS19780	COG2089	acid synthase
OM992_RS19785	COG0456	acetyltransferase
OM992_RS19790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OM992_RS19795	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OM992_RS19800	COG0463	Glycosyl transferase, family 2
OM992_RS19810	COG2363	Small membrane protein
OM992_RS19815	COG2233	PERMEase
OM992_RS19830	COG1216	Glycosyl transferase, family 2
OM992_RS19835	COG0351	phosphomethylpyrimidine kinase
OM992_RS19845	COG1621	beta-fructofuranosidase activity
OM992_RS19850	COG1263	PTS System
OM992_RS19850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS19855	COG3711	transcriptional antiterminator
OM992_RS19865	COG1404	Belongs to the peptidase S8 family
OM992_RS19870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OM992_RS19875	COG0778	Nitroreductase
OM992_RS19880	COG0772	Belongs to the SEDS family
OM992_RS19885	COG0454	-acetyltransferase
OM992_RS19905	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OM992_RS19910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OM992_RS19915	COG2261	transglycosylase associated protein
OM992_RS19920	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
OM992_RS19925	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OM992_RS19930	COG2246	polysaccharide biosynthetic process
OM992_RS19935	COG1309	transcriptional regulator
OM992_RS19955	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OM992_RS19960	COG2837	iron assimilation
OM992_RS19965	COG2822	iron ion transport
OM992_RS19970	COG0672	)-iron permease
OM992_RS19985	COG0583	DNA-binding transcription factor activity
OM992_RS19995	COG1346	cytolysis
OM992_RS20000	COG4895	conserved protein (DUF2196)
OM992_RS20005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OM992_RS20010	COG0346	lactoylglutathione lyase activity
OM992_RS20015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM992_RS20020	COG1404	Belongs to the peptidase S8 family
OM992_RS20025	COG1442	glycosyl transferase family 8
OM992_RS20030	COG2357	RelA SpoT domain protein
OM992_RS20035	COG1575	Belongs to the MenA family. Type 1 subfamily
OM992_RS20050	COG1696	Membrane protein involved in D-alanine export
OM992_RS20060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OM992_RS20065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OM992_RS20070	COG1486	melibiose metabolic process
OM992_RS20075	COG1447	Phosphotransferase system cellobiose-specific component IIA
OM992_RS20080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM992_RS20085	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OM992_RS20090	COG3711	transcriptional antiterminator
OM992_RS20090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OM992_RS20105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS20110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OM992_RS20115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS20120	COG0640	Transcriptional regulator
OM992_RS20125	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OM992_RS20130	COG0753	catalase activity
OM992_RS20135	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
OM992_RS20140	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OM992_RS20145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OM992_RS20150	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OM992_RS20155	COG4988	ABC transporter
OM992_RS20160	COG1294	oxidase, subunit
OM992_RS20165	COG1271	oxidase subunit
OM992_RS20170	COG3493	citrate carrier protein
OM992_RS20175	COG0726	polysaccharide deacetylase
OM992_RS20180	COG3842	ATPase activity
OM992_RS20185	COG2508	Transcriptional regulator
OM992_RS20190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS20200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OM992_RS20215	COG4894	glucomannan catabolic process
OM992_RS20220	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OM992_RS20225	COG0500	methyltransferase
OM992_RS20230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM992_RS20245	COG0753	catalase activity
OM992_RS20245	COG0693	protein deglycase activity
OM992_RS20250	COG2851	Citrate transporter
OM992_RS20255	COG2273	Hydrolase Family 16
OM992_RS20260	COG3711	transcriptional antiterminator
OM992_RS20265	COG2270	Major facilitator Superfamily
OM992_RS20270	COG0513	Belongs to the DEAD box helicase family
OM992_RS20310	COG0697	spore germination
OM992_RS20315	COG0589	response to stress
OM992_RS20320	COG2723	6-phospho-beta-galactosidase activity
OM992_RS20325	COG1263	PTS System
OM992_RS20325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OM992_RS20325	COG2190	(PTS) system
OM992_RS20335	COG0494	nUDIX hydrolase
OM992_RS20340	COG3507	Belongs to the glycosyl hydrolase 43 family
OM992_RS20350	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OM992_RS20355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OM992_RS20365	COG2390	Transcriptional regulator
OM992_RS20370	COG0561	phosphatase activity
OM992_RS20400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OM992_RS20405	COG5294	Protein conserved in bacteria
OM992_RS20410	COG0577	efflux transmembrane transporter activity
OM992_RS20415	COG1136	(ABC) transporter
OM992_RS20420	COG2205	protein histidine kinase activity
OM992_RS20425	COG0745	RESPONSE REGULATOR receiver
OM992_RS20430	COG0191	fructose-bisphosphate aldolase activity
OM992_RS20475	COG1349	DNA-binding transcription factor activity
OM992_RS20480	COG0667	Aldo Keto reductase
OM992_RS20485	COG2814	Major facilitator Superfamily
OM992_RS20495	COG1028	Short-chain dehydrogenase reductase Sdr
OM992_RS20500	COG2197	response regulator
OM992_RS20505	COG4585	Histidine kinase
OM992_RS20510	COG3239	Fatty acid desaturase
OM992_RS20515	COG1309	transcriptional regulator
OM992_RS20520	COG1012	belongs to the aldehyde dehydrogenase family
OM992_RS20525	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OM992_RS20535	COG0640	Transcriptional regulator
OM992_RS20540	COG2814	Major facilitator Superfamily
OM992_RS20545	COG1714	RDD family
OM992_RS20555	COG0450	alkyl hydroperoxide reductase
OM992_RS20560	COG3634	alkyl hydroperoxide reductase activity
OM992_RS20565	COG1113	amino acid transport
OM992_RS20575	COG2080	2 iron, 2 sulfur cluster binding
OM992_RS20590	COG2068	MobA-Related Protein
OM992_RS20595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OM992_RS20660	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OM992_RS20665	COG0456	acetyltransferase
OM992_RS20675	COG0457	Tetratricopeptide repeat
OM992_RS20680	COG0010	Belongs to the arginase family
OM992_RS20685	COG0833	amino acid
OM992_RS20690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OM992_RS20695	COG5658	integral membrane protein
OM992_RS20700	COG0640	Transcriptional regulator
OM992_RS20705	COG3829	transcription factor binding
OM992_RS20715	COG5002	protein histidine kinase activity
OM992_RS20715	COG3850	Histidine kinase
OM992_RS20725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OM992_RS20730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OM992_RS20735	COG4853	Protein conserved in bacteria
OM992_RS20740	COG4863	YycH protein
OM992_RS20745	COG5002	protein histidine kinase activity
OM992_RS20750	COG0745	RESPONSE REGULATOR receiver
OM992_RS20780	COG0346	lactoylglutathione lyase activity
OM992_RS20785	COG0305	Participates in initiation and elongation during chromosome replication
OM992_RS20800	COG3093	addiction module antidote protein HigA
OM992_RS20805	COG0438	transferase activity, transferring glycosyl groups
OM992_RS20815	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OM992_RS20820	COG0438	transferase activity, transferring glycosyl groups
OM992_RS20840	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
OM992_RS20845	COG4241	membrane
OM992_RS20855	COG5577	PFAM Coat F domain
OM992_RS20860	COG1733	regulation of RNA biosynthetic process
OM992_RS20870	COG0697	spore germination
OM992_RS20875	COG1621	beta-fructofuranosidase activity
OM992_RS20880	COG1621	beta-fructofuranosidase activity
OM992_RS20885	COG1802	Transcriptional regulator
OM992_RS20890	COG2318	DinB family
OM992_RS20895	COG2211	Major facilitator Superfamily
OM992_RS20900	COG2197	response regulator
OM992_RS20905	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OM992_RS20905	COG0512	Glutamine amidotransferase of anthranilate synthase
OM992_RS20910	COG0697	spore germination
OM992_RS20920	COG0583	DNA-binding transcription factor activity
OM992_RS20930	COG0778	Nitroreductase
OM992_RS20940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OM992_RS20945	COG1846	Transcriptional regulator
OM992_RS20950	COG2153	protein acetylation
OM992_RS20960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OM992_RS20965	COG0697	spore germination
OM992_RS20970	COG1078	dGTPase activity
OM992_RS20975	COG1331	Highly conserved protein containing a thioredoxin domain
OM992_RS20980	COG1266	CAAX protease self-immunity
OM992_RS20985	COG0477	Major facilitator Superfamily
OM992_RS20985	COG2814	Major facilitator Superfamily
OM992_RS20990	COG0346	lactoylglutathione lyase activity
OM992_RS20995	COG1609	Transcriptional regulator
OM992_RS21000	COG0708	Exodeoxyribonuclease III
OM992_RS21005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OM992_RS21010	COG2169	Transcriptional regulator
OM992_RS21020	COG0629	single-stranded DNA binding
OM992_RS21030	COG0012	GTP binding
OM992_RS21035	COG0243	molybdopterin cofactor binding
OM992_RS21040	COG4481	Protein conserved in bacteria
OM992_RS21045	COG3949	Membrane
OM992_RS21060	COG1475	DNA binding
OM992_RS21065	COG1192	Involved in chromosome partitioning
OM992_RS21090	COG1847	R3H domain protein
OM992_RS21095	COG0706	membrane insertase activity