locus-tag	class	description
BS1321_RS00015	COG0814	amino acid
BS1321_RS00020	COG0697	spore germination
BS1321_RS00060	COG0805	protein transport
BS1321_RS00070	COG1876	peptidase activity
BS1321_RS00075	COG1316	TRANSCRIPTIONal
BS1321_RS00095	COG0745	RESPONSE REGULATOR receiver
BS1321_RS00110	COG1086	Polysaccharide biosynthesis protein
BS1321_RS00115	COG1295	ribonuclease BN
BS1321_RS00175	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS1321_RS00180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BS1321_RS00185	COG0583	DNA-binding transcription factor activity
BS1321_RS00200	COG0519	Catalyzes the synthesis of GMP from XMP
BS1321_RS00205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS1321_RS00205	COG0456	acetyltransferase
BS1321_RS00235	COG0252	asparaginase activity
BS1321_RS00240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS1321_RS00255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS00265	COG2814	Major facilitator Superfamily
BS1321_RS00275	COG0640	Transcriptional regulator
BS1321_RS00285	COG0110	maltose O-acetyltransferase activity
BS1321_RS00295	COG1414	Transcriptional regulator
BS1321_RS00300	COG2814	Major facilitator Superfamily
BS1321_RS00310	COG2329	Antibiotic biosynthesis monooxygenase
BS1321_RS00315	COG0673	inositol 2-dehydrogenase activity
BS1321_RS00325	COG0656	L-ascorbic acid biosynthetic process
BS1321_RS00330	COG4221	oxidoreductase activity
BS1321_RS00335	COG2814	Major facilitator Superfamily
BS1321_RS00340	COG2207	Transcriptional regulator
BS1321_RS00365	COG3732	PTS system glucitol sorbitol-specific
BS1321_RS00390	COG2318	DinB family
BS1321_RS00395	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BS1321_RS00405	COG2068	MobA-Related Protein
BS1321_RS00410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS1321_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS00455	COG4638	Rieske (2fe-2S)
BS1321_RS00470	COG0028	Belongs to the TPP enzyme family
BS1321_RS00475	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS00490	COG1414	Transcriptional regulator
BS1321_RS00515	COG2188	Transcriptional regulator
BS1321_RS00535	COG3964	amidohydrolase
BS1321_RS00550	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS00560	COG2814	Major facilitator Superfamily
BS1321_RS00565	COG0673	inositol 2-dehydrogenase activity
BS1321_RS00575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS00575	COG1263	PTS System
BS1321_RS00580	COG3876	Protein conserved in bacteria
BS1321_RS00585	COG1472	Belongs to the glycosyl hydrolase 3 family
BS1321_RS00595	COG1263	PTS System
BS1321_RS00595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS00600	COG1737	Transcriptional regulator
BS1321_RS00605	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BS1321_RS00620	COG0411	ABC transporter
BS1321_RS00630	COG0559	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS00650	COG2030	dehydratase
BS1321_RS00660	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS00665	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS00670	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS00675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS1321_RS00680	COG0187	DNA topoisomerase II activity
BS1321_RS00685	COG1832	CoA-binding protein
BS1321_RS00690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BS1321_RS00695	COG0840	transmembrane signaling receptor activity
BS1321_RS00700	COG3093	addiction module antidote protein HigA
BS1321_RS00705	COG1695	Transcriptional regulator
BS1321_RS00715	COG4841	protein insertion into membrane
BS1321_RS00725	COG0824	Thioesterase
BS1321_RS00750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS00755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BS1321_RS00775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS1321_RS00780	COG2022	thiamine diphosphate biosynthetic process
BS1321_RS00790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS1321_RS00795	COG0352	thiamine-phosphate diphosphorylase activity
BS1321_RS00805	COG1122	ATPase activity
BS1321_RS00810	COG4721	ABC-type cobalt transport system, permease component
BS1321_RS00815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS1321_RS00825	COG2814	Major facilitator Superfamily
BS1321_RS00855	COG0251	oxidation-reduction process
BS1321_RS00870	COG1414	Transcriptional regulator
BS1321_RS00875	COG2368	4-hydroxyphenylacetate
BS1321_RS00885	COG0515	serine threonine protein kinase
BS1321_RS00900	COG1492	cobalamin metabolic process
BS1321_RS00975	COG0310	cobalt ion transport
BS1321_RS00990	COG1122	ATPase activity
BS1321_RS01000	COG1115	amino acid carrier protein
BS1321_RS01005	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS01015	COG0583	DNA-binding transcription factor activity
BS1321_RS01020	COG2271	Major facilitator Superfamily
BS1321_RS01025	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BS1321_RS01030	COG0583	DNA-binding transcription factor activity
BS1321_RS01050	COG2135	peptidase activity
BS1321_RS01055	COG0010	Belongs to the arginase family
BS1321_RS01065	COG0405	Gamma-glutamyltransferase
BS1321_RS01080	COG2358	TRAP transporter, solute receptor (TAXI family
BS1321_RS01085	COG0583	DNA-binding transcription factor activity
BS1321_RS01095	COG1288	antiporter activity
BS1321_RS01100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS1321_RS01105	COG0492	ferredoxin-NADP+ reductase activity
BS1321_RS01120	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS01125	COG2271	Major facilitator Superfamily
BS1321_RS01135	COG1414	Transcriptional regulator
BS1321_RS01150	COG2197	response regulator
BS1321_RS01160	COG2223	nitrite transmembrane transporter activity
BS1321_RS01190	COG0243	molybdopterin cofactor binding
BS1321_RS01200	COG1984	allophanate hydrolase subunit 2
BS1321_RS01205	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BS1321_RS01210	COG4336	lyase activity
BS1321_RS01215	COG1914	H( )-stimulated, divalent metal cation uptake system
BS1321_RS01220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BS1321_RS01230	COG2986	histidine ammonia-lyase
BS1321_RS01235	COG0477	Major facilitator Superfamily
BS1321_RS01240	COG1228	amidohydrolase
BS1321_RS01245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BS1321_RS01265	COG1309	transcriptional regulator
BS1321_RS01270	COG0277	FAD linked oxidase domain protein
BS1321_RS01275	COG2271	Major facilitator Superfamily
BS1321_RS01285	COG0697	spore germination
BS1321_RS01290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS01300	COG0346	lactoylglutathione lyase activity
BS1321_RS01315	COG2610	gluconate transmembrane transporter activity
BS1321_RS01320	COG1024	Enoyl-CoA hydratase
BS1321_RS01330	COG3829	transcription factor binding
BS1321_RS01335	COG0022	dehydrogenase e1 component
BS1321_RS01340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS1321_RS01355	COG1132	(ABC) transporter
BS1321_RS01360	COG1846	Transcriptional regulator
BS1321_RS01365	COG2153	protein acetylation
BS1321_RS01405	COG2851	Citrate transporter
BS1321_RS01410	COG3829	transcription factor binding
BS1321_RS01410	COG3290	protein histidine kinase activity
BS1321_RS01415	COG2186	Transcriptional regulator
BS1321_RS01425	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS1321_RS01430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS1321_RS01450	COG1113	amino acid transport
BS1321_RS01460	COG0805	protein transport
BS1321_RS01465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS01470	COG3540	Alkaline phosphatase
BS1321_RS01480	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS01485	COG0444	Belongs to the ABC transporter superfamily
BS1321_RS01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS01495	COG0601	transmembrane transport
BS1321_RS01500	COG0747	negative chemotaxis
BS1321_RS01510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS1321_RS01515	COG2271	Major facilitator Superfamily
BS1321_RS01520	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS1321_RS01525	COG2318	DinB family
BS1321_RS01530	COG2217	Heavy metal translocating P-type atpase
BS1321_RS01535	COG2608	mercury ion transmembrane transporter activity
BS1321_RS01540	COG1937	Protein conserved in bacteria
BS1321_RS01545	COG0583	DNA-binding transcription factor activity
BS1321_RS01555	COG0183	Belongs to the thiolase family
BS1321_RS01565	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS01570	COG0300	oxidoreductase activity
BS1321_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS01585	COG0583	DNA-binding transcription factor activity
BS1321_RS01595	COG2271	Major facilitator Superfamily
BS1321_RS01605	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS01610	COG0657	acetylesterase activity
BS1321_RS01620	COG2271	Major facilitator Superfamily
BS1321_RS01630	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS01645	COG1668	transmembrane transport
BS1321_RS01650	COG4152	abc transporter atp-binding protein
BS1321_RS01655	COG1349	DNA-binding transcription factor activity
BS1321_RS01660	COG0235	Class ii aldolase
BS1321_RS01665	COG1070	Carbohydrate kinase
BS1321_RS01670	COG1069	ribulokinase activity
BS1321_RS01675	COG1879	ABC-type sugar transport system periplasmic component
BS1321_RS01685	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS01690	COG1129	ABC transporter
BS1321_RS01695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS01700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS1321_RS01710	COG2972	Histidine kinase
BS1321_RS01715	COG1879	ABC-type sugar transport system periplasmic component
BS1321_RS01725	COG4806	L-rhamnose isomerase
BS1321_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS01730	COG3347	Dehydrogenase
BS1321_RS01740	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS1321_RS01755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS01770	COG2851	Citrate transporter
BS1321_RS01775	COG0583	DNA-binding transcription factor activity
BS1321_RS01780	COG2828	Protein conserved in bacteria
BS1321_RS01785	COG1053	succinate dehydrogenase
BS1321_RS01790	COG0583	DNA-binding transcription factor activity
BS1321_RS01800	COG2851	Citrate transporter
BS1321_RS01825	COG0697	spore germination
BS1321_RS01830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS1321_RS01850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS1321_RS01940	COG3766	membrane
BS1321_RS01945	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS1321_RS01950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS1321_RS01965	COG0501	Belongs to the peptidase M48B family
BS1321_RS01985	COG0730	response to heat
BS1321_RS01990	COG0425	Belongs to the sulfur carrier protein TusA family
BS1321_RS01995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS1321_RS01995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS02005	COG0425	Belongs to the sulfur carrier protein TusA family
BS1321_RS02005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS1321_RS02015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS1321_RS02020	COG2210	Belongs to the sulfur carrier protein TusA family
BS1321_RS02030	COG1937	Protein conserved in bacteria
BS1321_RS02045	COG0531	amino acid
BS1321_RS02050	COG2186	Transcriptional regulator
BS1321_RS02055	COG1794	racemase activity, acting on amino acids and derivatives
BS1321_RS02060	COG0583	DNA-binding transcription factor activity
BS1321_RS02070	COG0028	Belongs to the TPP enzyme family
BS1321_RS02075	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS02080	COG4319	ketosteroid isomerase
BS1321_RS02090	COG2271	Major facilitator Superfamily
BS1321_RS02100	COG3485	protocatechuate 3,4-dioxygenase
BS1321_RS02105	COG0183	Belongs to the thiolase family
BS1321_RS02115	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS02125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS1321_RS02140	COG0596	Alpha beta hydrolase
BS1321_RS02150	COG0163	prenyltransferase activity
BS1321_RS02155	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BS1321_RS02165	COG1349	DNA-binding transcription factor activity
BS1321_RS02170	COG0805	protein transport
BS1321_RS02175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS02180	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS02185	COG1473	amidohydrolase
BS1321_RS02200	COG0477	Major facilitator Superfamily
BS1321_RS02210	COG1522	sequence-specific DNA binding
BS1321_RS02215	COG0697	spore germination
BS1321_RS02235	COG1473	amidohydrolase
BS1321_RS02240	COG1473	amidohydrolase
BS1321_RS02245	COG2271	Major facilitator Superfamily
BS1321_RS02255	COG0346	lactoylglutathione lyase activity
BS1321_RS02260	COG0154	amidase activity
BS1321_RS02275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS1321_RS02280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS1321_RS02300	COG0477	Major facilitator Superfamily
BS1321_RS02310	COG0346	lactoylglutathione lyase activity
BS1321_RS02315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS02320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS02360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS02365	COG0791	NLP P60 protein
BS1321_RS02365	COG1388	LysM domain
BS1321_RS02375	COG0786	glutamate:sodium symporter activity
BS1321_RS02380	COG0010	Belongs to the arginase family
BS1321_RS02385	COG2204	response regulator
BS1321_RS02390	COG3852	Histidine kinase
BS1321_RS02395	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS02405	COG0833	amino acid
BS1321_RS02410	COG1473	amidohydrolase
BS1321_RS02440	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS02450	COG0183	Belongs to the thiolase family
BS1321_RS02455	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS02460	COG0183	Belongs to the thiolase family
BS1321_RS02470	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS02480	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS1321_RS02485	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BS1321_RS02490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BS1321_RS02495	COG2851	Citrate transporter
BS1321_RS02510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS02515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS02535	COG3507	Belongs to the glycosyl hydrolase 43 family
BS1321_RS02555	COG1414	Transcriptional regulator
BS1321_RS02560	COG0129	dihydroxy-acid dehydratase activity
BS1321_RS02565	COG2610	gluconate transmembrane transporter activity
BS1321_RS02580	COG0531	amino acid
BS1321_RS02585	COG1113	amino acid transport
BS1321_RS02595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS1321_RS02605	COG2124	cytochrome p450
BS1321_RS02615	COG2132	Multicopper oxidase
BS1321_RS02620	COG3104	oligopeptide transport
BS1321_RS02625	COG0784	Response regulator, receiver
BS1321_RS02625	COG2198	Histidine kinase
BS1321_RS02625	COG2205	protein histidine kinase activity
BS1321_RS02630	COG2205	protein histidine kinase activity
BS1321_RS02720	COG1131	(ABC) transporter
BS1321_RS02735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS1321_RS02750	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS02755	COG1113	amino acid transport
BS1321_RS02760	COG3290	protein histidine kinase activity
BS1321_RS02760	COG3829	transcription factor binding
BS1321_RS02765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BS1321_RS02790	COG2843	Capsule synthesis protein
BS1321_RS02855	COG1024	Enoyl-CoA hydratase
BS1321_RS02860	COG0071	Belongs to the small heat shock protein (HSP20) family
BS1321_RS02865	COG0419	ATPase involved in DNA repair
BS1321_RS02885	COG0425	Belongs to the sulfur carrier protein TusA family
BS1321_RS02890	COG2391	methyltransferase activity
BS1321_RS02895	COG4846	Membrane protein involved in cytochrome C biogenesis
BS1321_RS02900	COG0785	Cytochrome C biogenesis protein
BS1321_RS02910	COG2259	Doxx family
BS1321_RS02920	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS02925	COG3118	belongs to the thioredoxin family
BS1321_RS02940	COG3763	UPF0154 protein
BS1321_RS02955	COG4224	UPF0291 protein
BS1321_RS02960	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BS1321_RS02970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS1321_RS02975	COG1705	Flagellar rod assembly protein muramidase FlgJ
BS1321_RS03000	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BS1321_RS03015	COG0510	thiamine kinase activity
BS1321_RS03025	COG2076	Multidrug Resistance protein
BS1321_RS03030	COG2076	Multidrug Resistance protein
BS1321_RS03035	COG2188	Transcriptional regulator
BS1321_RS03040	COG0366	Alpha amylase catalytic
BS1321_RS03045	COG1263	PTS System
BS1321_RS03045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS03060	COG4335	DNA alkylation repair
BS1321_RS03065	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BS1321_RS03065	COG3608	succinylglutamate desuccinylase aspartoacylase
BS1321_RS03070	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BS1321_RS03080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BS1321_RS03095	COG4989	oxidoreductase activity
BS1321_RS03100	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS1321_RS03105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS1321_RS03120	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS1321_RS03130	COG1473	amidohydrolase
BS1321_RS03135	COG2814	Major facilitator Superfamily
BS1321_RS03140	COG3829	transcription factor binding
BS1321_RS03150	COG0488	(ABC) transporter
BS1321_RS03155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS1321_RS03165	COG0745	RESPONSE REGULATOR receiver
BS1321_RS03170	COG0596	Alpha beta hydrolase
BS1321_RS03185	COG2329	Antibiotic biosynthesis monooxygenase
BS1321_RS03200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS03210	COG0697	spore germination
BS1321_RS03220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BS1321_RS03225	COG0697	spore germination
BS1321_RS03230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS1321_RS03250	COG2211	Major facilitator Superfamily
BS1321_RS03255	COG1904	glucuronate isomerase
BS1321_RS03260	COG1940	carbohydrate kinase activity
BS1321_RS03270	COG0346	lactoylglutathione lyase activity
BS1321_RS03275	COG4974	Belongs to the 'phage' integrase family
BS1321_RS03280	COG2207	Transcriptional regulator
BS1321_RS03280	COG4753	response regulator
BS1321_RS03295	COG1178	ABC-type Fe3 transport system permease component
BS1321_RS03300	COG3842	ATPase activity
BS1321_RS03315	COG2814	Major facilitator Superfamily
BS1321_RS03325	COG1940	carbohydrate kinase activity
BS1321_RS03330	COG3842	ATPase activity
BS1321_RS03360	COG1653	transport
BS1321_RS03365	COG1175	transmembrane transport
BS1321_RS03370	COG0395	ABC-type sugar transport system, permease component
BS1321_RS03375	COG0366	Alpha amylase catalytic
BS1321_RS03385	COG0697	spore germination
BS1321_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS03400	COG2197	response regulator
BS1321_RS03425	COG4638	Rieske (2fe-2S)
BS1321_RS03435	COG0861	Integral membrane protein TerC family
BS1321_RS03440	COG2602	Beta-lactamase
BS1321_RS03455	COG0488	(ABC) transporter
BS1321_RS03475	COG1970	mechanosensitive ion channel activity
BS1321_RS03490	COG2076	Multidrug Resistance protein
BS1321_RS03495	COG0561	phosphatase activity
BS1321_RS03505	COG3842	ATPase activity
BS1321_RS03545	COG2318	DinB family
BS1321_RS03555	COG2814	Major facilitator Superfamily
BS1321_RS03560	COG2814	Major facilitator Superfamily
BS1321_RS03560	COG0477	Major facilitator Superfamily
BS1321_RS03570	COG1070	Carbohydrate kinase
BS1321_RS03580	COG1940	carbohydrate kinase activity
BS1321_RS03595	COG3764	Sortase (surface protein transpeptidase)
BS1321_RS03610	COG0702	epimerase
BS1321_RS03615	COG1733	regulation of RNA biosynthetic process
BS1321_RS03630	COG0011	TIGRFAM Protein of
BS1321_RS03640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS03645	COG0697	spore germination
BS1321_RS03655	COG0657	acetylesterase activity
BS1321_RS03665	COG1793	dna ligase
BS1321_RS03685	COG0174	glutamine synthetase
BS1321_RS03690	COG0789	Transcriptional regulator
BS1321_RS03695	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
BS1321_RS03700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS1321_RS03705	COG2860	membrane
BS1321_RS03710	COG0464	growth
BS1321_RS03715	COG1923	regulation of RNA biosynthetic process
BS1321_RS03720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BS1321_RS03730	COG0577	efflux transmembrane transporter activity
BS1321_RS03735	COG1136	(ABC) transporter
BS1321_RS03740	COG5002	protein histidine kinase activity
BS1321_RS03745	COG0745	RESPONSE REGULATOR receiver
BS1321_RS03770	COG1252	NADH dehydrogenase
BS1321_RS03780	COG1486	melibiose metabolic process
BS1321_RS03785	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS1321_RS03790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS1321_RS03795	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS1321_RS03800	COG2188	Transcriptional regulator
BS1321_RS03805	COG0367	asparagine synthase
BS1321_RS03825	COG1297	OPT oligopeptide transporter protein
BS1321_RS03835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BS1321_RS03840	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BS1321_RS03850	COG4550	Control of competence regulator ComK, YlbF/YmcA
BS1321_RS03855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS1321_RS03860	COG1063	alcohol dehydrogenase
BS1321_RS03870	COG1013	pyruvate-flavodoxin oxidoreductase activity
BS1321_RS03875	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BS1321_RS03875	COG0674	pyruvate-flavodoxin oxidoreductase activity
BS1321_RS03885	COG2359	stage V sporulation protein S
BS1321_RS03890	COG1692	metallophosphoesterase
BS1321_RS03900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BS1321_RS03905	COG1058	Belongs to the CinA family
BS1321_RS03905	COG1546	Belongs to the CinA family
BS1321_RS03910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BS1321_RS03915	COG1426	Protein conserved in bacteria
BS1321_RS03930	COG0300	oxidoreductase activity
BS1321_RS03935	COG0612	Peptidase, M16
BS1321_RS03940	COG0612	Peptidase, M16
BS1321_RS03945	COG1079	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS03950	COG4603	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS03955	COG3845	ABC transporter
BS1321_RS03960	COG1744	ABC transporter substrate-binding protein PnrA-like
BS1321_RS03965	COG2188	Transcriptional regulator
BS1321_RS03975	COG1674	ftsk spoiiie
BS1321_RS03975	COG4980	gas vesicle protein
BS1321_RS03985	COG0740	serine-type endopeptidase activity
BS1321_RS03990	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS1321_RS03995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS1321_RS04000	COG0527	aspartate kinase activity
BS1321_RS04005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BS1321_RS04010	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS1321_RS04015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS1321_RS04020	COG1873	PFAM PRC-barrel domain
BS1321_RS04025	COG0612	Peptidase, M16
BS1321_RS04030	COG0726	polysaccharide deacetylase
BS1321_RS04035	COG1185	polyribonucleotide nucleotidyltransferase activity
BS1321_RS04045	COG0196	riboflavin kinase activity
BS1321_RS04050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BS1321_RS04055	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BS1321_RS04060	COG1550	Protein conserved in bacteria
BS1321_RS04065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BS1321_RS04070	COG1358	cellular component organization or biogenesis
BS1321_RS04075	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BS1321_RS04080	COG0195	Participates in both transcription termination and antitermination
BS1321_RS04085	COG0779	Required for maturation of 30S ribosomal subunits
BS1321_RS04090	COG2176	DNA-directed DNA polymerase activity
BS1321_RS04100	COG0750	zinc metalloprotease
BS1321_RS04105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BS1321_RS04110	COG4589	Belongs to the CDS family
BS1321_RS04125	COG0528	UMP kinase activity
BS1321_RS04145	COG1191	sigma factor activity
BS1321_RS04150	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BS1321_RS04155	COG1776	CheC inhibitor of MCP methylation
BS1321_RS04165	COG0643	Histidine kinase
BS1321_RS04165	COG2198	Histidine kinase
BS1321_RS04175	COG0455	bacterial-type flagellum organization
BS1321_RS04180	COG1419	protein localization to endoplasmic reticulum
BS1321_RS04185	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS1321_RS04190	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS1321_RS04195	COG1684	flagellar biosynthetic protein fliR
BS1321_RS04200	COG1987	bacterial-type flagellum assembly
BS1321_RS04205	COG1338	Plays a role in the flagellum-specific transport system
BS1321_RS04210	COG3190	flagellar
BS1321_RS04215	COG2201	protein-glutamate methylesterase activity
BS1321_RS04220	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS1321_RS04220	COG1776	CheC inhibitor of MCP methylation
BS1321_RS04225	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS1321_RS04230	COG1580	Controls the rotational direction of flagella during chemotaxis
BS1321_RS04235	COG1582	Flagellar protein (FlbD)
BS1321_RS04250	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BS1321_RS04265	COG2882	bacterial-type flagellum organization
BS1321_RS04270	COG1157	protein secretion by the type III secretion system
BS1321_RS04275	COG1317	bacterial-type flagellum organization
BS1321_RS04280	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BS1321_RS04285	COG1766	The M ring may be actively involved in energy transduction
BS1321_RS04290	COG1677	Flagellar hook-basal body complex protein FliE
BS1321_RS04295	COG1558	bacterial-type flagellum-dependent cell motility
BS1321_RS04300	COG1815	bacterial-type flagellum-dependent cell motility
BS1321_RS04305	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS1321_RS04310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BS1321_RS04320	COG4974	Belongs to the 'phage' integrase family
BS1321_RS04325	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BS1321_RS04330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS1321_RS04335	COG0758	DNA mediated transformation
BS1321_RS04340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BS1321_RS04345	COG0045	succinate-CoA ligase (ADP-forming) activity
BS1321_RS04350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BS1321_RS04360	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS1321_RS04365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS1321_RS04375	COG0335	large ribosomal subunit rRNA binding
BS1321_RS04380	COG0336	Belongs to the RNA methyltransferase TrmD family
BS1321_RS04385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BS1321_RS04395	COG1837	Belongs to the UPF0109 family
BS1321_RS04400	COG0228	four-way junction DNA binding
BS1321_RS04405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BS1321_RS04415	COG0552	protein localization to endoplasmic reticulum
BS1321_RS04420	COG1196	nuclear chromosome segregation
BS1321_RS04425	COG0571	ribonuclease III activity
BS1321_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS04440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BS1321_RS04450	COG1349	DNA-binding transcription factor activity
BS1321_RS04455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BS1321_RS04460	COG1760	l-serine dehydratase
BS1321_RS04465	COG1760	l-serine dehydratase
BS1321_RS04470	COG1461	Dihydroxyacetone kinase
BS1321_RS04475	COG1302	Protein conserved in bacteria
BS1321_RS04480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BS1321_RS04490	COG1564	THIamine pyrophosphokinase
BS1321_RS04495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BS1321_RS04500	COG1162	GTPase activity
BS1321_RS04505	COG0515	serine threonine protein kinase
BS1321_RS04505	COG2815	serine threonine protein kinase
BS1321_RS04510	COG0631	protein serine/threonine phosphatase activity
BS1321_RS04515	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BS1321_RS04520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS1321_RS04520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BS1321_RS04525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BS1321_RS04535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BS1321_RS04540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BS1321_RS04555	COG0194	GDP metabolic process
BS1321_RS04565	COG1561	YicC-like family, N-terminal region
BS1321_RS04570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BS1321_RS04580	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BS1321_RS04590	COG0167	dihydroorotate dehydrogenase activity
BS1321_RS04600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BS1321_RS04610	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS1321_RS04615	COG0540	Belongs to the ATCase OTCase family
BS1321_RS04625	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BS1321_RS04630	COG0564	pseudouridine synthase activity
BS1321_RS04635	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BS1321_RS04645	COG3599	regulation of cell shape
BS1321_RS04650	COG2302	S4 RNA-binding domain
BS1321_RS04655	COG0762	integral membrane protein
BS1321_RS04660	COG1799	cell septum assembly
BS1321_RS04665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BS1321_RS04670	COG1496	oxidoreductase activity
BS1321_RS04675	COG1873	PFAM PRC-barrel domain
BS1321_RS04680	COG1191	sigma factor activity
BS1321_RS04685	COG1191	sigma factor activity
BS1321_RS04695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BS1321_RS04700	COG0849	cell division
BS1321_RS04705	COG3856	small basic protein
BS1321_RS04710	COG3879	Bacterial protein of unknown function (DUF881)
BS1321_RS04715	COG3879	Bacterial protein of unknown function (DUF881)
BS1321_RS04720	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BS1321_RS04725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BS1321_RS04730	COG0772	Belongs to the SEDS family
BS1321_RS04735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BS1321_RS04740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS1321_RS04750	COG0768	penicillin binding
BS1321_RS04755	COG0768	penicillin binding
BS1321_RS04770	COG2001	Belongs to the MraZ family
BS1321_RS04775	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BS1321_RS04785	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS1321_RS04790	COG0454	-acetyltransferase
BS1321_RS04800	COG1024	Enoyl-CoA hydratase
BS1321_RS04805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BS1321_RS04810	COG1399	metal-binding, possibly nucleic acid-binding protein
BS1321_RS04815	COG1323	Belongs to the UPF0348 family
BS1321_RS04820	COG3480	Lon protease (S16) C-terminal proteolytic domain
BS1321_RS04825	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS1321_RS04830	COG3314	Sporulation integral membrane protein YlbJ
BS1321_RS04835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BS1321_RS04840	COG0742	ribosomal rna small subunit methyltransferase
BS1321_RS04855	COG4471	UPF0298 protein
BS1321_RS04865	COG3679	Belongs to the UPF0342 family
BS1321_RS04885	COG2340	Cysteine-rich secretory protein family
BS1321_RS04900	COG3336	cytochrome c oxidase
BS1321_RS04925	COG0109	protoheme IX farnesyltransferase activity
BS1321_RS04930	COG1612	heme a metabolic process
BS1321_RS04935	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BS1321_RS04940	COG4838	Belongs to the UPF0358 family
BS1321_RS04945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BS1321_RS04950	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BS1321_RS04960	COG4896	Protein conserved in bacteria
BS1321_RS04980	COG1217	gtp-binding protein TYPA
BS1321_RS04990	COG0483	inositol monophosphate 1-phosphatase activity
BS1321_RS05030	COG4476	Belongs to the UPF0223 family
BS1321_RS05040	COG1982	Orn Lys Arg decarboxylase major
BS1321_RS05055	COG0726	polysaccharide deacetylase
BS1321_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS1321_RS05075	COG0022	dehydrogenase e1 component
BS1321_RS05085	COG0497	DNA recombination
BS1321_RS05100	COG0561	phosphatase activity
BS1321_RS05105	COG5503	Protein of unknown function (DUF1447)
BS1321_RS05110	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS1321_RS05115	COG0569	domain protein
BS1321_RS05120	COG1473	amidohydrolase
BS1321_RS05125	COG2171	N-acyltransferase activity
BS1321_RS05130	COG0583	DNA-binding transcription factor activity
BS1321_RS05140	COG0477	Major facilitator Superfamily
BS1321_RS05145	COG0517	IMP dehydrogenase activity
BS1321_RS05155	COG4703	Protein of unknown function (DUF1797)
BS1321_RS05180	COG2200	EAL domain
BS1321_RS05185	COG0471	metal ion transport
BS1321_RS05185	COG0490	domain, Protein
BS1321_RS05190	COG1408	metallophosphoesterase
BS1321_RS05195	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS1321_RS05200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BS1321_RS05215	COG0784	Response regulator, receiver
BS1321_RS05215	COG0835	chemotaxis
BS1321_RS05220	COG0598	Magnesium transport protein CorA
BS1321_RS05225	COG0436	Aminotransferase
BS1321_RS05235	COG2084	Dehydrogenase
BS1321_RS05245	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BS1321_RS05250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS1321_RS05255	COG0390	transport system, permease component
BS1321_RS05260	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BS1321_RS05265	COG1525	nuclease
BS1321_RS05280	COG4873	Protein conserved in bacteria
BS1321_RS05290	COG3949	Membrane
BS1321_RS05295	COG1164	Oligoendopeptidase f
BS1321_RS05300	COG1846	Transcriptional regulator
BS1321_RS05305	COG3852	Histidine kinase
BS1321_RS05310	COG2223	nitrite transmembrane transporter activity
BS1321_RS05325	COG5002	protein histidine kinase activity
BS1321_RS05330	COG3594	Acyltransferase
BS1321_RS05355	COG1024	Enoyl-CoA hydratase
BS1321_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS05380	COG1024	Enoyl-CoA hydratase
BS1321_RS05385	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS05395	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS05405	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS05410	COG3852	Histidine kinase
BS1321_RS05415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS1321_RS05430	COG1191	sigma factor activity
BS1321_RS05435	COG0861	Integral membrane protein TerC family
BS1321_RS05445	COG0772	Belongs to the SEDS family
BS1321_RS05450	COG1757	Na H antiporter
BS1321_RS05455	COG0679	Auxin Efflux Carrier
BS1321_RS05460	COG0281	malic enzyme
BS1321_RS05465	COG4565	transcriptional regulatory protein
BS1321_RS05470	COG3290	protein histidine kinase activity
BS1321_RS05480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BS1321_RS05495	COG1131	(ABC) transporter
BS1321_RS05500	COG1725	Transcriptional regulator
BS1321_RS05505	COG1764	response to oxidative stress
BS1321_RS05515	COG0584	glycerophosphoryl diester phosphodiesterase
BS1321_RS05540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS1321_RS05540	COG1181	Belongs to the D-alanine--D-alanine ligase family
BS1321_RS05550	COG3871	stress protein (general stress protein 26)
BS1321_RS05555	COG1363	Peptidase, m42
BS1321_RS05565	COG0747	negative chemotaxis
BS1321_RS05570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS05575	COG0601	transmembrane transport
BS1321_RS05580	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS05590	COG0670	Belongs to the BI1 family
BS1321_RS05595	COG1607	acyl-coa hydrolase
BS1321_RS05600	COG1876	peptidase activity
BS1321_RS05605	COG2318	DinB family
BS1321_RS05610	COG1132	(ABC) transporter
BS1321_RS05620	COG1247	-acetyltransferase
BS1321_RS05635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BS1321_RS05645	COG0352	thiamine-phosphate diphosphorylase activity
BS1321_RS05645	COG0351	phosphomethylpyrimidine kinase
BS1321_RS05650	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BS1321_RS05655	COG0352	thiamine-phosphate diphosphorylase activity
BS1321_RS05660	COG0477	Major facilitator Superfamily
BS1321_RS05665	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS05670	COG2309	aminopeptidase activity
BS1321_RS05680	COG1278	Cold shock
BS1321_RS05700	COG5583	Uncharacterized small protein (DUF2292)
BS1321_RS05705	COG0531	amino acid
BS1321_RS05710	COG2017	converts alpha-aldose to the beta-anomer
BS1321_RS05725	COG3883	PFAM NLP P60 protein
BS1321_RS05725	COG0791	NLP P60 protein
BS1321_RS05735	COG4208	sulfate ABC transporter
BS1321_RS05745	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BS1321_RS05750	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS1321_RS05760	COG3483	tryptophan 2,3-dioxygenase activity
BS1321_RS05765	COG1113	amino acid transport
BS1321_RS05770	COG3844	kynureninase activity
BS1321_RS05775	COG2272	Belongs to the type-B carboxylesterase lipase family
BS1321_RS05780	COG0789	Transcriptional regulator
BS1321_RS05785	COG0659	secondary active sulfate transmembrane transporter activity
BS1321_RS05790	COG2723	6-phospho-beta-galactosidase activity
BS1321_RS05795	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS05805	COG0673	inositol 2-dehydrogenase activity
BS1321_RS05810	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS05815	COG2814	Major facilitator Superfamily
BS1321_RS05820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS1321_RS05825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS05835	COG5337	Spore coat protein CotH
BS1321_RS05850	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS05855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS1321_RS05860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS1321_RS05885	COG2323	membrane
BS1321_RS05890	COG0693	protein deglycase activity
BS1321_RS05930	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS1321_RS05935	COG2382	esterase
BS1321_RS05940	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BS1321_RS05945	COG2153	protein acetylation
BS1321_RS05965	COG0210	DNA helicase
BS1321_RS05985	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS1321_RS06020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BS1321_RS06025	COG2239	Acts as a magnesium transporter
BS1321_RS06035	COG0564	pseudouridine synthase activity
BS1321_RS06045	COG2357	RelA SpoT domain protein
BS1321_RS06050	COG4116	CYTH
BS1321_RS06055	COG0741	lytic transglycosylase activity
BS1321_RS06060	COG2346	COG2346, Truncated hemoglobins
BS1321_RS06065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS1321_RS06075	COG1164	Oligoendopeptidase f
BS1321_RS06080	COG4469	Competence protein
BS1321_RS06085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS1321_RS06090	COG4862	establishment of competence for transformation
BS1321_RS06095	COG1393	Belongs to the ArsC family
BS1321_RS06105	COG0456	acetyltransferase
BS1321_RS06120	COG0180	Tryptophanyl-tRNA synthetase
BS1321_RS06130	COG5504	Zn-dependent protease
BS1321_RS06135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS1321_RS06140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS1321_RS06160	COG2267	carboxylic ester hydrolase activity
BS1321_RS06170	COG0542	response to heat
BS1321_RS06175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BS1321_RS06190	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS1321_RS06205	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BS1321_RS06215	COG0505	Belongs to the CarA family
BS1321_RS06225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BS1321_RS06230	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BS1321_RS06235	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BS1321_RS06240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BS1321_RS06245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS1321_RS06250	COG2151	metal-sulfur cluster biosynthetic enzyme
BS1321_RS06255	COG1073	alpha beta
BS1321_RS06260	COG0561	phosphatase activity
BS1321_RS06270	COG3729	General stress protein
BS1321_RS06275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS06280	COG1307	EDD domain protein, DegV family
BS1321_RS06290	COG1666	GTP binding
BS1321_RS06295	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS06300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS06305	COG1609	Transcriptional regulator
BS1321_RS06310	COG0366	Alpha amylase catalytic
BS1321_RS06315	COG1874	Beta-galactosidase
BS1321_RS06315	COG0366	Alpha amylase catalytic
BS1321_RS06320	COG2182	Extracellular solute-binding protein
BS1321_RS06330	COG0367	asparagine synthase
BS1321_RS06345	COG2311	Membrane
BS1321_RS06350	COG2271	Major facilitator Superfamily
BS1321_RS06400	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BS1321_RS06410	COG0398	Pfam SNARE associated Golgi protein
BS1321_RS06425	COG2333	competence protein COMEC
BS1321_RS06425	COG0658	competence protein
BS1321_RS06435	COG4903	ComK protein
BS1321_RS06445	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS06450	COG0501	Belongs to the peptidase M48B family
BS1321_RS06455	COG2197	response regulator
BS1321_RS06460	COG1418	mRNA catabolic process
BS1321_RS06465	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS06470	COG0095	Lipoate-protein ligase
BS1321_RS06475	COG1234	tRNA 3'-trailer cleavage
BS1321_RS06485	COG1309	transcriptional regulator
BS1321_RS06490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BS1321_RS06495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BS1321_RS06500	COG2329	Antibiotic biosynthesis monooxygenase
BS1321_RS06505	COG0671	phosphoesterase, PA-phosphatase related
BS1321_RS06510	COG1473	amidohydrolase
BS1321_RS06520	COG4473	ABC transporter
BS1321_RS06525	COG1131	(ABC) transporter
BS1321_RS06530	COG0537	adenosine 5'-monophosphoramidase activity
BS1321_RS06550	COG4980	gas vesicle protein
BS1321_RS06555	COG1846	Transcriptional regulator
BS1321_RS06585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS1321_RS06605	COG1120	ATPase activity
BS1321_RS06615	COG4717	serine-type aminopeptidase activity
BS1321_RS06620	COG0420	3'-5' exonuclease activity
BS1321_RS06625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS1321_RS06635	COG1024	Enoyl-CoA hydratase
BS1321_RS06640	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS06650	COG1834	amidinotransferase
BS1321_RS06695	COG0832	Belongs to the urease beta subunit family
BS1321_RS06715	COG0561	phosphatase activity
BS1321_RS06720	COG3679	Belongs to the UPF0342 family
BS1321_RS06730	COG0189	ligase activity
BS1321_RS06735	COG0189	ligase activity
BS1321_RS06740	COG0189	ligase activity
BS1321_RS06745	COG0189	ligase activity
BS1321_RS06775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS1321_RS06780	COG2011	ABC-type metal ion transport system permease component
BS1321_RS06785	COG1464	Belongs to the NlpA lipoprotein family
BS1321_RS06790	COG0371	Dehydrogenase
BS1321_RS06800	COG2508	Transcriptional regulator
BS1321_RS06805	COG3842	ATPase activity
BS1321_RS06815	COG0114	fumarate hydratase activity
BS1321_RS06820	COG0626	cystathionine gamma-synthase activity
BS1321_RS06825	COG0626	cystathionine gamma-synthase activity
BS1321_RS06830	COG0254	rRNA binding
BS1321_RS06835	COG1132	(ABC) transporter
BS1321_RS06840	COG1132	(ABC) transporter
BS1321_RS06855	COG0768	penicillin binding
BS1321_RS06860	COG0516	GMP reductase activity
BS1321_RS06860	COG0517	IMP dehydrogenase activity
BS1321_RS06865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BS1321_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS06890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BS1321_RS06895	COG0753	catalase activity
BS1321_RS06900	COG1522	sequence-specific DNA binding
BS1321_RS06910	COG1522	sequence-specific DNA binding
BS1321_RS06915	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS1321_RS06920	COG1113	amino acid transport
BS1321_RS06930	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS1321_RS06950	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS1321_RS06960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS1321_RS06965	COG0589	response to stress
BS1321_RS06970	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS1321_RS06975	COG3852	Histidine kinase
BS1321_RS06980	COG1253	flavin adenine dinucleotide binding
BS1321_RS06985	COG0586	Pfam SNARE associated Golgi protein
BS1321_RS06995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS07000	COG1253	flavin adenine dinucleotide binding
BS1321_RS07005	COG0628	permease
BS1321_RS07020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS07030	COG0456	acetyltransferase
BS1321_RS07040	COG1054	Belongs to the UPF0176 family
BS1321_RS07050	COG2851	Citrate transporter
BS1321_RS07055	COG2814	Major facilitator Superfamily
BS1321_RS07060	COG2271	Major facilitator Superfamily
BS1321_RS07065	COG0824	Thioesterase
BS1321_RS07070	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS07075	COG0183	Belongs to the thiolase family
BS1321_RS07080	COG1024	Enoyl-CoA hydratase
BS1321_RS07085	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS07090	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS07105	COG0659	secondary active sulfate transmembrane transporter activity
BS1321_RS07110	COG1227	inorganic diphosphatase activity
BS1321_RS07115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS1321_RS07120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS1321_RS07125	COG0716	FMN binding
BS1321_RS07130	COG1278	Cold shock
BS1321_RS07145	COG4149	molybdate abc transporter
BS1321_RS07150	COG1393	Belongs to the ArsC family
BS1321_RS07155	COG5002	protein histidine kinase activity
BS1321_RS07190	COG3327	negative regulation of DNA-templated transcription, initiation
BS1321_RS07195	COG1024	Enoyl-CoA hydratase
BS1321_RS07200	COG0183	Belongs to the thiolase family
BS1321_RS07205	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS07210	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS07215	COG1024	Enoyl-CoA hydratase
BS1321_RS07220	COG1024	Enoyl-CoA hydratase
BS1321_RS07245	COG3396	Phenylacetate-CoA oxygenase
BS1321_RS07255	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BS1321_RS07275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BS1321_RS07280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BS1321_RS07285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS1321_RS07295	COG2508	Transcriptional regulator
BS1321_RS07300	COG2233	PERMEase
BS1321_RS07305	COG3195	allantoin biosynthetic process
BS1321_RS07305	COG3648	Uricase
BS1321_RS07310	COG2351	hydroxyisourate hydrolase activity
BS1321_RS07330	COG2368	4-hydroxyphenylacetate
BS1321_RS07350	COG0697	spore germination
BS1321_RS07355	COG0405	Gamma-glutamyltransferase
BS1321_RS07360	COG2059	Chromate
BS1321_RS07365	COG2059	Chromate
BS1321_RS07370	COG1522	sequence-specific DNA binding
BS1321_RS07375	COG3850	Histidine kinase
BS1321_RS07375	COG5002	protein histidine kinase activity
BS1321_RS07380	COG0745	RESPONSE REGULATOR receiver
BS1321_RS07385	COG0398	Pfam SNARE associated Golgi protein
BS1321_RS07400	COG2814	Major facilitator Superfamily
BS1321_RS07415	COG1414	Transcriptional regulator
BS1321_RS07420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS07430	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS07435	COG2271	Major facilitator Superfamily
BS1321_RS07525	COG1595	DNA-templated transcription, initiation
BS1321_RS07530	COG1388	LysM domain
BS1321_RS07530	COG0791	NLP P60 protein
BS1321_RS07540	COG3344	reverse transcriptase
BS1321_RS07545	COG0657	acetylesterase activity
BS1321_RS07550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS1321_RS07555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BS1321_RS07560	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BS1321_RS07565	COG0640	Transcriptional regulator
BS1321_RS07575	COG2890	protein-(glutamine-N5) methyltransferase activity
BS1321_RS07610	COG2719	SpoVR family
BS1321_RS07615	COG3949	Membrane
BS1321_RS07620	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS07630	COG1473	amidohydrolase
BS1321_RS07640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BS1321_RS07660	COG0431	NADPH-dependent FMN reductase
BS1321_RS07665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS1321_RS07670	COG3153	acetyltransferase
BS1321_RS07670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS1321_RS07675	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS1321_RS07680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS07690	COG0564	pseudouridine synthase activity
BS1321_RS07695	COG2261	transglycosylase associated protein
BS1321_RS07700	COG0656	L-ascorbic acid biosynthetic process
BS1321_RS07705	COG0306	phosphate transporter
BS1321_RS07710	COG1392	Phosphate transport regulator
BS1321_RS07715	COG0306	phosphate transporter
BS1321_RS07720	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BS1321_RS07720	COG2508	Transcriptional regulator
BS1321_RS07725	COG2217	Heavy metal translocating P-type atpase
BS1321_RS07730	COG0686	Belongs to the AlaDH PNT family
BS1321_RS07735	COG0277	FAD linked oxidase domain protein
BS1321_RS07740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS1321_RS07745	COG0477	Major facilitator Superfamily
BS1321_RS07750	COG2094	Belongs to the DNA glycosylase MPG family
BS1321_RS07755	COG0701	Predicted permease
BS1321_RS07760	COG3689	TIGRFAM TIGR03943 family protein
BS1321_RS07765	COG0791	NLP P60 protein
BS1321_RS07765	COG1388	LysM domain
BS1321_RS07775	COG3961	Belongs to the TPP enzyme family
BS1321_RS07785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BS1321_RS07795	COG0778	Nitroreductase
BS1321_RS07805	COG0385	Bile acid
BS1321_RS07840	COG0463	Glycosyl transferase, family 2
BS1321_RS07850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS1321_RS07865	COG1113	amino acid transport
BS1321_RS07875	COG2807	transmembrane transport
BS1321_RS07890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS1321_RS07900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS1321_RS07910	COG4464	protein tyrosine phosphatase activity
BS1321_RS07915	COG0489	protein tyrosine kinase activity
BS1321_RS07920	COG3944	biosynthesis protein
BS1321_RS07965	COG2766	serine protein kinase
BS1321_RS07970	COG0531	amino acid
BS1321_RS07975	COG2066	Belongs to the glutaminase family
BS1321_RS07980	COG4191	Histidine kinase
BS1321_RS07985	COG0784	Response regulator, receiver
BS1321_RS07990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS07995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS08000	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS08005	COG1120	ATPase activity
BS1321_RS08010	COG0778	Nitroreductase
BS1321_RS08015	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BS1321_RS08025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BS1321_RS08030	COG3382	B3 4 domain protein
BS1321_RS08050	COG2130	NADP-dependent
BS1321_RS08055	COG2239	Acts as a magnesium transporter
BS1321_RS08065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS08110	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS08115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS1321_RS08130	COG2814	Major facilitator Superfamily
BS1321_RS08140	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BS1321_RS08150	COG1473	amidohydrolase
BS1321_RS08160	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS08170	COG0477	Major facilitator Superfamily
BS1321_RS08175	COG1309	transcriptional regulator
BS1321_RS08215	COG1609	Transcriptional regulator
BS1321_RS08225	COG0191	fructose-bisphosphate aldolase activity
BS1321_RS08230	COG1082	Xylose isomerase domain protein TIM barrel
BS1321_RS08235	COG1082	Xylose isomerase domain protein TIM barrel
BS1321_RS08240	COG0673	inositol 2-dehydrogenase activity
BS1321_RS08245	COG2814	Major facilitator Superfamily
BS1321_RS08255	COG3962	Belongs to the TPP enzyme family
BS1321_RS08260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS08265	COG3718	enzyme involved in inositol metabolism
BS1321_RS08280	COG0477	Major facilitator Superfamily
BS1321_RS08285	COG1011	Hydrolase
BS1321_RS08290	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS08305	COG0473	3-isopropylmalate dehydrogenase activity
BS1321_RS08310	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS08315	COG4638	Rieske (2fe-2S)
BS1321_RS08320	COG1141	Ferredoxin
BS1321_RS08330	COG3829	transcription factor binding
BS1321_RS08340	COG1595	DNA-templated transcription, initiation
BS1321_RS08350	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS1321_RS08355	COG0531	amino acid
BS1321_RS08360	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS08375	COG0697	spore germination
BS1321_RS08415	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS08430	COG1388	LysM domain
BS1321_RS08455	COG3546	catalase activity
BS1321_RS08470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS1321_RS08475	COG5577	PFAM Coat F domain
BS1321_RS08480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BS1321_RS08485	COG1011	Hydrolase
BS1321_RS08500	COG1063	alcohol dehydrogenase
BS1321_RS08505	COG0584	glycerophosphoryl diester phosphodiesterase
BS1321_RS08510	COG2205	protein histidine kinase activity
BS1321_RS08515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS1321_RS08525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS1321_RS08560	COG0582	viral genome integration into host DNA
BS1321_RS08570	COG2066	Belongs to the glutaminase family
BS1321_RS08585	COG4974	Belongs to the 'phage' integrase family
BS1321_RS08690	COG0735	belongs to the Fur family
BS1321_RS08705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BS1321_RS08715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS1321_RS08720	COG1607	acyl-coa hydrolase
BS1321_RS08735	COG4555	ABC transporter
BS1321_RS08745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS1321_RS08750	COG0069	glutamate synthase activity
BS1321_RS08750	COG0070	glutamate synthase
BS1321_RS08750	COG0067	glutamate synthase
BS1321_RS08755	COG4129	membrane
BS1321_RS08765	COG1566	PFAM secretion protein HlyD family protein
BS1321_RS08770	COG2814	Major facilitator Superfamily
BS1321_RS08775	COG0655	NAD(P)H dehydrogenase (quinone) activity
BS1321_RS08790	COG1132	(ABC) transporter
BS1321_RS08795	COG3557	Belongs to the UPF0374 family
BS1321_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS08825	COG1194	a g-specific adenine glycosylase
BS1321_RS08830	COG1988	membrane-bound metal-dependent
BS1321_RS08855	COG1090	epimerase
BS1321_RS08875	COG0183	Belongs to the thiolase family
BS1321_RS08880	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS08900	COG0583	DNA-binding transcription factor activity
BS1321_RS08910	COG1126	abc transporter atp-binding protein
BS1321_RS08915	COG0765	amino acid transport
BS1321_RS08925	COG0628	permease
BS1321_RS08930	COG0166	Belongs to the GPI family
BS1321_RS08945	COG2814	Major facilitator Superfamily
BS1321_RS08950	COG5002	protein histidine kinase activity
BS1321_RS08950	COG5001	Diguanylate cyclase
BS1321_RS08970	COG1695	Transcriptional regulator
BS1321_RS08985	COG1388	LysM domain
BS1321_RS08985	COG0791	NLP P60 protein
BS1321_RS08995	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BS1321_RS09005	COG0436	Aminotransferase
BS1321_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS09045	COG0765	amino acid transport
BS1321_RS09050	COG1126	abc transporter atp-binding protein
BS1321_RS09060	COG0745	RESPONSE REGULATOR receiver
BS1321_RS09065	COG2205	protein histidine kinase activity
BS1321_RS09075	COG0577	efflux transmembrane transporter activity
BS1321_RS09080	COG1136	(ABC) transporter
BS1321_RS09095	COG3069	C4-dicarboxylate transmembrane transporter activity
BS1321_RS09100	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS1321_RS09105	COG1131	(ABC) transporter
BS1321_RS09125	COG4975	Glucose uptake
BS1321_RS09130	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS09135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS09140	COG1464	Belongs to the NlpA lipoprotein family
BS1321_RS09145	COG2011	ABC-type metal ion transport system permease component
BS1321_RS09160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS09165	COG1473	amidohydrolase
BS1321_RS09170	COG0456	acetyltransferase
BS1321_RS09175	COG1126	abc transporter atp-binding protein
BS1321_RS09180	COG0765	amino acid transport
BS1321_RS09185	COG0765	amino acid transport
BS1321_RS09190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS09195	COG0456	acetyltransferase
BS1321_RS09200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BS1321_RS09205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS09210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS09215	COG0583	DNA-binding transcription factor activity
BS1321_RS09225	COG0277	FAD linked oxidase domain protein
BS1321_RS09230	COG1113	amino acid transport
BS1321_RS09235	COG1113	amino acid transport
BS1321_RS09245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS09255	COG0165	Argininosuccinate lyase
BS1321_RS09265	COG3842	ATPase activity
BS1321_RS09270	COG1840	ABC-type Fe3 transport system, periplasmic component
BS1321_RS09285	COG1126	abc transporter atp-binding protein
BS1321_RS09290	COG0765	amino acid transport
BS1321_RS09295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS09300	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS09315	COG0601	transmembrane transport
BS1321_RS09320	COG0747	negative chemotaxis
BS1321_RS09325	COG3314	Sporulation integral membrane protein YlbJ
BS1321_RS09345	COG0579	oxidoreductase
BS1321_RS09350	COG1072	(Pantothenic acid kinase))
BS1321_RS09365	COG1113	amino acid transport
BS1321_RS09375	COG0156	8-amino-7-oxononanoate synthase activity
BS1321_RS09390	COG4807	Protein conserved in bacteria
BS1321_RS09395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BS1321_RS09400	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS1321_RS09425	COG0535	radical SAM domain protein
BS1321_RS09435	COG0387	Pfam Sodium calcium exchanger
BS1321_RS09440	COG0477	Major facilitator Superfamily
BS1321_RS09445	COG2217	Heavy metal translocating P-type atpase
BS1321_RS09450	COG1295	ribonuclease BN
BS1321_RS09460	COG4840	Belongs to the UPF0435 family
BS1321_RS09465	COG0303	'Molybdopterin
BS1321_RS09470	COG1763	Mo-molybdopterin cofactor biosynthetic process
BS1321_RS09480	COG0024	Methionine aminopeptidase
BS1321_RS09485	COG0693	protein deglycase activity
BS1321_RS09495	COG1360	Flagellar Motor Protein
BS1321_RS09500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BS1321_RS09505	COG3180	Ammonia monooxygenase
BS1321_RS09510	COG1077	Cell shape determining protein MreB Mrl
BS1321_RS09515	COG0582	viral genome integration into host DNA
BS1321_RS09520	COG0490	domain, Protein
BS1321_RS09525	COG0475	glutathione-regulated potassium exporter activity
BS1321_RS09535	COG1295	ribonuclease BN
BS1321_RS09540	COG2404	hydrolase activity, acting on ester bonds
BS1321_RS09550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS1321_RS09550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS1321_RS09555	COG0307	riboflavin synthase, alpha
BS1321_RS09565	COG0626	cystathionine gamma-synthase activity
BS1321_RS09575	COG0513	Belongs to the DEAD box helicase family
BS1321_RS09580	COG5002	protein histidine kinase activity
BS1321_RS09585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS09590	COG0243	molybdopterin cofactor binding
BS1321_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS09605	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS09615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS1321_RS09620	COG0778	Nitroreductase
BS1321_RS09630	COG2027	D-alanyl-D-alanine carboxypeptidase
BS1321_RS09645	COG0840	transmembrane signaling receptor activity
BS1321_RS09650	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BS1321_RS09655	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS1321_RS09660	COG3584	3D domain protein
BS1321_RS09660	COG1388	LysM domain
BS1321_RS09665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BS1321_RS09670	COG1301	dicarboxylic acid transport
BS1321_RS09675	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS09680	COG0628	permease
BS1321_RS09685	COG0427	acetyl-CoA hydrolase
BS1321_RS09690	COG3279	Response regulator of the LytR AlgR family
BS1321_RS09700	COG0347	Belongs to the P(II) protein family
BS1321_RS09705	COG0004	ammonium transporteR
BS1321_RS09710	COG2879	small protein
BS1321_RS09715	COG1966	Carbon starvation protein
BS1321_RS09720	COG1132	(ABC) transporter
BS1321_RS09725	COG1132	(ABC) transporter
BS1321_RS09730	COG0778	Nitroreductase
BS1321_RS09735	COG0527	aspartate kinase activity
BS1321_RS09740	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BS1321_RS09765	COG1845	cytochrome c oxidase, subunit III
BS1321_RS09775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BS1321_RS09785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS1321_RS09800	COG3620	sequence-specific DNA binding
BS1321_RS09810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS1321_RS09820	COG1733	regulation of RNA biosynthetic process
BS1321_RS09825	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS09830	COG1129	ABC transporter
BS1321_RS09845	COG1114	Component of the transport system for branched-chain amino acids
BS1321_RS09850	COG0667	Aldo Keto reductase
BS1321_RS09855	COG0697	spore germination
BS1321_RS09860	COG1187	pseudouridine synthase activity
BS1321_RS09870	COG0673	inositol 2-dehydrogenase activity
BS1321_RS09875	COG0673	inositol 2-dehydrogenase activity
BS1321_RS09885	COG1609	Transcriptional regulator
BS1321_RS09910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS09920	COG0596	Alpha beta hydrolase
BS1321_RS09930	COG1136	(ABC) transporter
BS1321_RS09935	COG0577	efflux transmembrane transporter activity
BS1321_RS09940	COG3850	Histidine kinase
BS1321_RS09940	COG5002	protein histidine kinase activity
BS1321_RS09950	COG0385	Bile acid
BS1321_RS09955	COG2733	membrane
BS1321_RS09990	COG1397	ADP-ribosylglycohydrolase
BS1321_RS10010	COG5444	nuclease activity
BS1321_RS10025	COG2234	aminopeptidase activity
BS1321_RS10035	COG3852	Histidine kinase
BS1321_RS10040	COG2204	response regulator
BS1321_RS10060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS1321_RS10065	COG4708	membrane
BS1321_RS10075	COG5002	protein histidine kinase activity
BS1321_RS10085	COG2372	response to copper ion
BS1321_RS10085	COG1276	copper resistance
BS1321_RS10090	COG4549	nuclear export factor GLE1
BS1321_RS10095	COG1404	Belongs to the peptidase S8 family
BS1321_RS10100	COG0653	protein targeting
BS1321_RS10105	COG0778	Nitroreductase
BS1321_RS10110	COG3853	Toxic anion resistance protein (TelA)
BS1321_RS10115	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BS1321_RS10135	COG0004	ammonium transporteR
BS1321_RS10155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BS1321_RS10165	COG2323	membrane
BS1321_RS10170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS10185	COG0456	acetyltransferase
BS1321_RS10190	COG1597	lipid kinase activity
BS1321_RS10210	COG1595	DNA-templated transcription, initiation
BS1321_RS10215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS1321_RS10220	COG0154	amidase activity
BS1321_RS10225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BS1321_RS10230	COG4851	CamS sex pheromone cAM373 precursor
BS1321_RS10235	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BS1321_RS10240	COG0210	DNA helicase
BS1321_RS10245	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BS1321_RS10250	COG4496	protein, YerC YecD
BS1321_RS10255	COG1470	cell adhesion involved in biofilm formation
BS1321_RS10270	COG0151	Belongs to the GarS family
BS1321_RS10275	COG0138	bifunctional purine biosynthesis protein purh
BS1321_RS10280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BS1321_RS10285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BS1321_RS10290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS1321_RS10300	COG0047	phosphoribosylformylglycinamidine synthase activity
BS1321_RS10305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BS1321_RS10315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BS1321_RS10320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BS1321_RS10325	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BS1321_RS10350	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BS1321_RS10355	COG1609	Transcriptional regulator
BS1321_RS10360	COG2814	Major facilitator Superfamily
BS1321_RS10365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BS1321_RS10375	COG2814	Major facilitator Superfamily
BS1321_RS10395	COG2190	(PTS) system
BS1321_RS10395	COG1263	PTS System
BS1321_RS10395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS10400	COG3711	transcriptional antiterminator
BS1321_RS10405	COG2252	PERMEase
BS1321_RS10410	COG0519	Catalyzes the synthesis of GMP from XMP
BS1321_RS10410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BS1321_RS10415	COG1305	Transglutaminase-like
BS1321_RS10420	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BS1321_RS10425	COG0714	Associated with various cellular activities
BS1321_RS10435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS10445	COG1511	domain protein
BS1321_RS10450	COG1674	ftsk spoiiie
BS1321_RS10455	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS1321_RS10460	COG5417	Belongs to the EsaB family
BS1321_RS10465	COG4842	Belongs to the WXG100 family
BS1321_RS10480	COG2113	Glycine betaine
BS1321_RS10485	COG0517	IMP dehydrogenase activity
BS1321_RS10485	COG4175	Glycine betaine
BS1321_RS10490	COG0833	amino acid
BS1321_RS10495	COG2986	histidine ammonia-lyase
BS1321_RS10505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS10510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BS1321_RS10520	COG0697	spore germination
BS1321_RS10525	COG0531	amino acid
BS1321_RS10550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS1321_RS10620	COG3711	transcriptional antiterminator
BS1321_RS10625	COG0405	Gamma-glutamyltransferase
BS1321_RS10630	COG2271	Major facilitator Superfamily
BS1321_RS10640	COG2247	cell wall binding repeat
BS1321_RS10640	COG2385	sporulation resulting in formation of a cellular spore
BS1321_RS10655	COG0459	protein refolding
BS1321_RS10665	COG1266	CAAX protease self-immunity
BS1321_RS10675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BS1321_RS10680	COG0315	cyclic pyranopterin monophosphate synthase activity
BS1321_RS10685	COG0488	(ABC) transporter
BS1321_RS10695	COG0456	acetyltransferase
BS1321_RS10700	COG1214	PFAM Peptidase M22, glycoprotease
BS1321_RS10705	COG0802	atpase or kinase
BS1321_RS10805	COG2183	response to ionizing radiation
BS1321_RS10810	COG2208	phosphoserine phosphatase activity
BS1321_RS10815	COG1191	sigma factor activity
BS1321_RS10820	COG2172	sigma factor antagonist activity
BS1321_RS10825	COG1366	Belongs to the anti-sigma-factor antagonist family
BS1321_RS10830	COG2208	phosphoserine phosphatase activity
BS1321_RS10835	COG2172	sigma factor antagonist activity
BS1321_RS10840	COG1366	Belongs to the anti-sigma-factor antagonist family
BS1321_RS10845	COG1366	Belongs to the anti-sigma-factor antagonist family
BS1321_RS10850	COG2337	Toxic component of a toxin-antitoxin (TA) module
BS1321_RS10855	COG0864	Transcriptional regulator
BS1321_RS10865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BS1321_RS10870	COG0736	holo-[acyl-carrier-protein] synthase activity
BS1321_RS10875	COG0705	Rhomboid family
BS1321_RS10880	COG3428	Bacterial PH domain
BS1321_RS10885	COG3402	PFAM membrane-flanked domain
BS1321_RS10890	COG0513	Belongs to the DEAD box helicase family
BS1321_RS10895	COG2208	phosphoserine phosphatase activity
BS1321_RS10900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BS1321_RS10935	COG1597	lipid kinase activity
BS1321_RS10940	COG1309	transcriptional regulator
BS1321_RS10945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS1321_RS10950	COG4974	Belongs to the 'phage' integrase family
BS1321_RS11000	COG2208	phosphoserine phosphatase activity
BS1321_RS11005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS1321_RS11010	COG2198	Histidine kinase
BS1321_RS11010	COG2205	protein histidine kinase activity
BS1321_RS11010	COG0784	Response regulator, receiver
BS1321_RS11015	COG1253	flavin adenine dinucleotide binding
BS1321_RS11020	COG0789	Transcriptional regulator
BS1321_RS11030	COG0672	)-iron permease
BS1321_RS11035	COG2837	iron assimilation
BS1321_RS11040	COG2822	iron ion transport
BS1321_RS11045	COG1846	Transcriptional regulator
BS1321_RS11050	COG2814	Major facilitator Superfamily
BS1321_RS11065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS1321_RS11070	COG2819	hydrolase of the alpha beta superfamily
BS1321_RS11075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS11080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS11085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS11090	COG1120	ATPase activity
BS1321_RS11095	COG2190	(PTS) system
BS1321_RS11095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS11095	COG1263	PTS System
BS1321_RS11100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BS1321_RS11105	COG0363	glucosamine-6-phosphate deaminase activity
BS1321_RS11110	COG2188	Transcriptional regulator
BS1321_RS11115	COG4821	SIS domain
BS1321_RS11120	COG1033	growth of symbiont in host cell
BS1321_RS11120	COG2409	Drug exporters of the RND superfamily
BS1321_RS11135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS1321_RS11140	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BS1321_RS11145	COG1177	transmembrane transport
BS1321_RS11150	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS1321_RS11155	COG3842	ATPase activity
BS1321_RS11165	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BS1321_RS11170	COG0456	acetyltransferase
BS1321_RS11175	COG0025	NhaP-type Na H and K H
BS1321_RS11180	COG1597	lipid kinase activity
BS1321_RS11205	COG3835	regulator
BS1321_RS11225	COG0167	dihydroorotate dehydrogenase activity
BS1321_RS11235	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BS1321_RS11250	COG1278	Cold shock
BS1321_RS11255	COG0840	transmembrane signaling receptor activity
BS1321_RS11285	COG1132	(ABC) transporter
BS1321_RS11295	COG5002	protein histidine kinase activity
BS1321_RS11300	COG5646	InterPro IPR014922
BS1321_RS11305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BS1321_RS11310	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS1321_RS11315	COG4856	YbbR-like protein
BS1321_RS11320	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BS1321_RS11325	COG5662	AntiSigma factor
BS1321_RS11330	COG1595	DNA-templated transcription, initiation
BS1321_RS11410	COG0726	polysaccharide deacetylase
BS1321_RS11415	COG2194	sulfuric ester hydrolase activity
BS1321_RS11425	COG0489	protein tyrosine kinase activity
BS1321_RS11430	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS1321_RS11450	COG2814	Major facilitator Superfamily
BS1321_RS11460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BS1321_RS11465	COG0101	tRNA pseudouridine synthase activity
BS1321_RS11470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BS1321_RS11475	COG1122	ATPase activity
BS1321_RS11480	COG1122	ATPase activity
BS1321_RS11485	COG0203	ribosomal protein L17
BS1321_RS11490	COG0202	RNA polymerase activity
BS1321_RS11495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BS1321_RS11505	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BS1321_RS11510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BS1321_RS11515	COG0563	adenylate kinase activity
BS1321_RS11520	COG0201	protein transport
BS1321_RS11525	COG0200	Binds to the 23S rRNA
BS1321_RS11530	COG1841	ribosomal large subunit assembly
BS1321_RS11535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BS1321_RS11540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BS1321_RS11545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BS1321_RS11550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BS1321_RS11555	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS1321_RS11565	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BS1321_RS11570	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BS1321_RS11575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BS1321_RS11580	COG0255	Belongs to the universal ribosomal protein uL29 family
BS1321_RS11585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BS1321_RS11590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BS1321_RS11595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BS1321_RS11600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BS1321_RS11605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BS1321_RS11615	COG0088	Forms part of the polypeptide exit tunnel
BS1321_RS11620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BS1321_RS11625	COG0051	transcription antitermination factor activity, RNA binding
BS1321_RS11630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BS1321_RS11635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BS1321_RS11640	COG0049	tRNA binding
BS1321_RS11645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BS1321_RS11650	COG1358	cellular component organization or biogenesis
BS1321_RS11655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BS1321_RS11660	COG0085	RNA polymerase activity
BS1321_RS11665	COG2813	Specifically methylates the guanine in position
BS1321_RS11670	COG0222	ribosome binding
BS1321_RS11680	COG0081	regulation of translation
BS1321_RS11685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BS1321_RS11690	COG0250	Participates in transcription elongation, termination and antitermination
BS1321_RS11695	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS1321_RS11700	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS1321_RS11710	COG3688	RNA-binding protein containing a PIN domain
BS1321_RS11715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS1321_RS11725	COG0215	cysteine-tRNA ligase activity
BS1321_RS11730	COG1045	serine acetyltransferase
BS1321_RS11735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS1321_RS11740	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BS1321_RS11750	COG4956	integral membrane protein (PIN domain superfamily)
BS1321_RS11760	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BS1321_RS11765	COG0542	response to heat
BS1321_RS11770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BS1321_RS11775	COG3880	PFAM UvrB UvrC protein
BS1321_RS11800	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BS1321_RS11805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BS1321_RS11810	COG1396	sequence-specific DNA binding
BS1321_RS11815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BS1321_RS11820	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BS1321_RS11825	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BS1321_RS11830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS1321_RS11835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BS1321_RS11840	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BS1321_RS11845	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BS1321_RS11850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS1321_RS11855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BS1321_RS11860	COG0037	tRNA processing
BS1321_RS11865	COG0515	serine threonine protein kinase
BS1321_RS11870	COG2304	oxidoreductase activity
BS1321_RS11875	COG2208	phosphoserine phosphatase activity
BS1321_RS11890	COG1098	S1 RNA binding domain
BS1321_RS11910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BS1321_RS11915	COG3956	TIGRFAM MazG family protein
BS1321_RS11920	COG2244	polysaccharide biosynthetic process
BS1321_RS11925	COG2002	toxin-antitoxin pair type II binding
BS1321_RS11930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BS1321_RS11945	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BS1321_RS11950	COG1116	anion transmembrane transporter activity
BS1321_RS11955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS1321_RS11960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS11965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS1321_RS11975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BS1321_RS11985	COG2088	sporulation resulting in formation of a cellular spore
BS1321_RS11990	COG0251	oxidation-reduction process
BS1321_RS11995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS1321_RS12000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BS1321_RS12010	COG4466	Protein conserved in bacteria
BS1321_RS12030	COG3584	3D domain protein
BS1321_RS12030	COG3583	domain protein
BS1321_RS12035	COG0084	hydrolase, TatD family'
BS1321_RS12045	COG2002	toxin-antitoxin pair type II binding
BS1321_RS12050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BS1321_RS12060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BS1321_RS12065	COG4467	Involved in initiation control of chromosome replication
BS1321_RS12070	COG1774	PSP1 C-terminal conserved region
BS1321_RS12075	COG0470	DNA polymerase III
BS1321_RS12085	COG3870	Protein conserved in bacteria
BS1321_RS12090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BS1321_RS12095	COG1982	Orn Lys Arg decarboxylase major
BS1321_RS12145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BS1321_RS12150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BS1321_RS12155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BS1321_RS12165	COG0590	tRNA wobble adenosine to inosine editing
BS1321_RS12170	COG1335	isochorismatase
BS1321_RS12175	COG1428	Deoxynucleoside kinase
BS1321_RS12180	COG1428	Deoxynucleoside kinase
BS1321_RS12190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BS1321_RS12200	COG0517	IMP dehydrogenase activity
BS1321_RS12200	COG0516	GMP reductase activity
BS1321_RS12235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BS1321_RS12245	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BS1321_RS12250	COG0187	DNA topoisomerase II activity
BS1321_RS12260	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BS1321_RS12265	COG2501	S4 domain
BS1321_RS12270	COG0592	DNA-directed DNA polymerase activity
BS1321_RS12275	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BS1321_RS12290	COG0594	ribonuclease P activity
BS1321_RS12295	COG0706	membrane insertase activity
BS1321_RS12300	COG1847	R3H domain protein
BS1321_RS12310	COG0445	tRNA wobble uridine modification
BS1321_RS12315	COG0357	Ribosomal RNA small subunit methyltransferase G
BS1321_RS12320	COG1475	DNA binding
BS1321_RS12325	COG1192	Involved in chromosome partitioning
BS1321_RS12330	COG1475	DNA binding
BS1321_RS12345	COG0668	transmembrane transport
BS1321_RS12350	COG4481	Protein conserved in bacteria
BS1321_RS12355	COG0012	GTP binding
BS1321_RS12360	COG0360	Binds together with S18 to 16S ribosomal RNA
BS1321_RS12370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BS1321_RS12380	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BS1321_RS12385	COG0359	binds to the 23S rRNA
BS1321_RS12390	COG0305	Participates in initiation and elongation during chromosome replication
BS1321_RS12420	COG1196	nuclear chromosome segregation
BS1321_RS12420	COG0739	heme binding
BS1321_RS12420	COG0741	lytic transglycosylase activity
BS1321_RS12425	COG0745	RESPONSE REGULATOR receiver
BS1321_RS12430	COG5002	protein histidine kinase activity
BS1321_RS12440	COG4853	Protein conserved in bacteria
BS1321_RS12445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BS1321_RS12450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS1321_RS12460	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BS1321_RS12465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BS1321_RS12480	COG0753	catalase activity
BS1321_RS12480	COG0693	protein deglycase activity
BS1321_RS12485	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS1321_RS12495	COG5337	Spore coat protein CotH
BS1321_RS12515	COG0076	glutamate decarboxylase activity
BS1321_RS12540	COG1609	Transcriptional regulator
BS1321_RS12545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS12550	COG1869	D-ribose catabolic process
BS1321_RS12555	COG1129	ABC transporter
BS1321_RS12560	COG1172	Belongs to the binding-protein-dependent transport system permease family
BS1321_RS12565	COG1879	ABC-type sugar transport system periplasmic component
BS1321_RS12570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS1321_RS12575	COG0583	DNA-binding transcription factor activity
BS1321_RS12585	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BS1321_RS12595	COG1301	dicarboxylic acid transport
BS1321_RS12600	COG2267	carboxylic ester hydrolase activity
BS1321_RS12615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS12620	COG3162	membrane
BS1321_RS12630	COG1136	(ABC) transporter
BS1321_RS12635	COG1136	(ABC) transporter
BS1321_RS12635	COG0577	efflux transmembrane transporter activity
BS1321_RS12640	COG0745	RESPONSE REGULATOR receiver
BS1321_RS12645	COG5002	protein histidine kinase activity
BS1321_RS12655	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS1321_RS12660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS1321_RS12660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS1321_RS12665	COG1366	Belongs to the anti-sigma-factor antagonist family
BS1321_RS12670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BS1321_RS12680	COG0765	amino acid transport
BS1321_RS12685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS12705	COG0788	formyltetrahydrofolate deformylase activity
BS1321_RS12715	COG4895	conserved protein (DUF2196)
BS1321_RS12720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS1321_RS12720	COG0723	plastoquinol--plastocyanin reductase activity
BS1321_RS12745	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BS1321_RS12755	COG0363	glucosamine-6-phosphate deaminase activity
BS1321_RS12785	COG2252	PERMEase
BS1321_RS12810	COG0488	(ABC) transporter
BS1321_RS12815	COG0551	DNA topoisomerase type I activity
BS1321_RS12815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS1321_RS12825	COG0726	polysaccharide deacetylase
BS1321_RS12830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS12835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS12840	COG1120	ATPase activity
BS1321_RS12845	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BS1321_RS12850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS1321_RS12860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BS1321_RS12875	COG2096	Adenosyltransferase
BS1321_RS12895	COG1070	Carbohydrate kinase
BS1321_RS12900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BS1321_RS12910	COG0561	phosphatase activity
BS1321_RS12925	COG1846	Transcriptional regulator
BS1321_RS12930	COG2814	Major facilitator Superfamily
BS1321_RS12940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS1321_RS12945	COG0351	phosphomethylpyrimidine kinase
BS1321_RS12950	COG0746	molybdenum cofactor guanylyltransferase activity
BS1321_RS12955	COG0314	molybdopterin synthase activity
BS1321_RS12960	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BS1321_RS12965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BS1321_RS12980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BS1321_RS12995	COG2363	Small membrane protein
BS1321_RS13005	COG3253	May function as heme-dependent peroxidase
BS1321_RS13010	COG0280	phosphate acetyltransferase
BS1321_RS13030	COG4844	belongs to the
BS1321_RS13035	COG1078	dGTPase activity
BS1321_RS13040	COG3465	dGTPase activity
BS1321_RS13050	COG1994	Peptidase M50
BS1321_RS13060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS1321_RS13065	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BS1321_RS13070	COG0010	Belongs to the arginase family
BS1321_RS13080	COG0018	arginyl-trna synthetase
BS1321_RS13090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS1321_RS13095	COG0247	lactate metabolic process
BS1321_RS13095	COG2181	nitrate reductase activity
BS1321_RS13100	COG0183	Belongs to the thiolase family
BS1321_RS13105	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS13110	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS13115	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS13125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS1321_RS13125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS1321_RS13125	COG1703	isobutyryl-CoA mutase activity
BS1321_RS13130	COG3343	RNA polymerase activity
BS1321_RS13135	COG0504	CTP synthase activity
BS1321_RS13140	COG4821	SIS domain
BS1321_RS13145	COG2204	response regulator
BS1321_RS13155	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BS1321_RS13160	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BS1321_RS13165	COG1494	fructose-1,6-bisphosphatase
BS1321_RS13170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BS1321_RS13180	COG1435	thymidine kinase activity
BS1321_RS13190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BS1321_RS13210	COG0009	L-threonylcarbamoyladenylate synthase
BS1321_RS13215	COG1971	Probably functions as a manganese efflux pump
BS1321_RS13230	COG0698	ribose 5-phosphate isomerase
BS1321_RS13245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BS1321_RS13250	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS1321_RS13255	COG1404	Belongs to the peptidase S8 family
BS1321_RS13265	COG0356	it plays a direct role in the translocation of protons across the membrane
BS1321_RS13270	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS1321_RS13280	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BS1321_RS13295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BS1321_RS13305	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS1321_RS13310	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS1321_RS13315	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS1321_RS13320	COG0649	NAD binding
BS1321_RS13330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS1321_RS13335	COG0839	Belongs to the complex I subunit 6 family
BS1321_RS13340	COG0713	ATP synthesis coupled electron transport
BS1321_RS13345	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS1321_RS13350	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BS1321_RS13355	COG1007	ATP synthesis coupled electron transport
BS1321_RS13360	COG4836	Membrane
BS1321_RS13375	COG2385	sporulation resulting in formation of a cellular spore
BS1321_RS13385	COG0739	heme binding
BS1321_RS13390	COG1609	Transcriptional regulator
BS1321_RS13395	COG1077	Cell shape determining protein MreB Mrl
BS1321_RS13400	COG4786	Flagellar basal body rod
BS1321_RS13405	COG4786	Flagellar basal body rod
BS1321_RS13430	COG0629	single-stranded DNA binding
BS1321_RS13435	COG0444	Belongs to the ABC transporter superfamily
BS1321_RS13440	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS13445	COG0747	negative chemotaxis
BS1321_RS13450	COG0601	transmembrane transport
BS1321_RS13455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS13470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS13475	COG1279	arginine transmembrane transporter activity
BS1321_RS13480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS1321_RS13485	COG4715	Zinc finger, swim domain protein
BS1321_RS13510	COG0768	penicillin binding
BS1321_RS13520	COG2247	cell wall binding repeat
BS1321_RS13520	COG2385	sporulation resulting in formation of a cellular spore
BS1321_RS13525	COG1785	Belongs to the alkaline phosphatase family
BS1321_RS13530	COG0653	protein targeting
BS1321_RS13545	COG1368	sulfuric ester hydrolase activity
BS1321_RS13550	COG1316	TRANSCRIPTIONal
BS1321_RS13555	COG1388	LysM domain
BS1321_RS13555	COG0791	NLP P60 protein
BS1321_RS13560	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS1321_RS13565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BS1321_RS13570	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS1321_RS13575	COG1442	glycosyl transferase family 8
BS1321_RS13575	COG1216	Glycosyl transferase, family 2
BS1321_RS13580	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS1321_RS13585	COG1682	transport, permease protein
BS1321_RS13590	COG1134	teichoic acid transport
BS1321_RS13595	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS13600	COG0728	peptidoglycan biosynthetic process
BS1321_RS13620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BS1321_RS13625	COG1316	TRANSCRIPTIONal
BS1321_RS13630	COG1739	Uncharacterized protein family UPF0029
BS1321_RS13635	COG4585	Histidine kinase
BS1321_RS13640	COG2197	response regulator
BS1321_RS13645	COG1307	EDD domain protein, DegV family
BS1321_RS13650	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BS1321_RS13680	COG4786	Flagellar basal body rod
BS1321_RS13680	COG1256	bacterial-type flagellum assembly
BS1321_RS13685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS1321_RS13700	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BS1321_RS13705	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BS1321_RS13710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BS1321_RS13720	COG1334	flagellar protein FlaG
BS1321_RS13725	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BS1321_RS13730	COG1516	flagellar protein fliS
BS1321_RS13740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BS1321_RS13750	COG1396	sequence-specific DNA binding
BS1321_RS13755	COG0653	protein targeting
BS1321_RS13765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS13775	COG2884	Cell division ATP-binding protein ftsE
BS1321_RS13780	COG2177	Part of the ABC transporter FtsEX involved in
BS1321_RS13785	COG0791	NLP P60 protein
BS1321_RS13785	COG3883	PFAM NLP P60 protein
BS1321_RS13790	COG0793	Belongs to the peptidase S41A family
BS1321_RS13790	COG3409	Peptidoglycan-binding domain 1 protein
BS1321_RS13795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BS1321_RS13800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS13805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS13810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS13815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS13820	COG2353	YceI-like domain
BS1321_RS13830	COG0753	catalase activity
BS1321_RS13835	COG4897	Protein conserved in bacteria
BS1321_RS13840	COG0556	nucleotide-excision repair
BS1321_RS13845	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BS1321_RS13850	COG3595	metallopeptidase activity
BS1321_RS13870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BS1321_RS13875	COG0546	phosphoglycolate phosphatase activity
BS1321_RS13880	COG0110	maltose O-acetyltransferase activity
BS1321_RS13885	COG3764	Sortase (surface protein transpeptidase)
BS1321_RS13895	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BS1321_RS13900	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BS1321_RS13905	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS1321_RS13910	COG0131	Imidazoleglycerol-phosphate dehydratase
BS1321_RS13915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BS1321_RS13920	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BS1321_RS13925	COG0107	imidazoleglycerol-phosphate synthase activity
BS1321_RS13930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BS1321_RS13930	COG0140	phosphoribosyl-ATP diphosphatase activity
BS1321_RS13935	COG0457	Tetratricopeptide repeat
BS1321_RS13940	COG0492	ferredoxin-NADP+ reductase activity
BS1321_RS13945	COG1051	belongs to the nudix hydrolase family
BS1321_RS13950	COG1660	Displays ATPase and GTPase activities
BS1321_RS13955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BS1321_RS13965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS1321_RS13970	COG0740	serine-type endopeptidase activity
BS1321_RS13980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BS1321_RS13995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS1321_RS14000	COG0126	phosphoglycerate kinase activity
BS1321_RS14005	COG0149	triose-phosphate isomerase activity
BS1321_RS14010	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BS1321_RS14025	COG1876	peptidase activity
BS1321_RS14035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BS1321_RS14040	COG1647	Serine aminopeptidase, S33
BS1321_RS14045	COG0557	exoribonuclease II activity
BS1321_RS14050	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BS1321_RS14065	COG2427	Protein of unknown function (DUF1641)
BS1321_RS14070	COG3383	formate dehydrogenase (NAD+) activity
BS1321_RS14075	COG5609	conserved protein (DUF2294)
BS1321_RS14080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BS1321_RS14085	COG0583	DNA-binding transcription factor activity
BS1321_RS14110	COG3290	protein histidine kinase activity
BS1321_RS14120	COG3239	Fatty acid desaturase
BS1321_RS14125	COG4585	Histidine kinase
BS1321_RS14130	COG2197	response regulator
BS1321_RS14135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS1321_RS14140	COG0745	RESPONSE REGULATOR receiver
BS1321_RS14145	COG3850	Histidine kinase
BS1321_RS14145	COG5002	protein histidine kinase activity
BS1321_RS14160	COG1657	PFAM Prenyltransferase squalene oxidase
BS1321_RS14170	COG4844	belongs to the
BS1321_RS14175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS14180	COG4605	iron ion homeostasis
BS1321_RS14185	COG4604	ABC transporter, ATP-binding protein
BS1321_RS14190	COG4607	ABC-type enterochelin transport system periplasmic component
BS1321_RS14200	COG1368	sulfuric ester hydrolase activity
BS1321_RS14205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BS1321_RS14245	COG0366	Alpha amylase catalytic
BS1321_RS14250	COG0833	amino acid
BS1321_RS14255	COG1609	Transcriptional regulator
BS1321_RS14260	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS1321_RS14265	COG1121	(ABC) transporter
BS1321_RS14270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS1321_RS14270	COG1321	iron dependent repressor
BS1321_RS14275	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS1321_RS14280	COG0772	Belongs to the SEDS family
BS1321_RS14285	COG5577	PFAM Coat F domain
BS1321_RS14295	COG0506	proline dehydrogenase activity
BS1321_RS14305	COG1024	Enoyl-CoA hydratase
BS1321_RS14305	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS14310	COG0183	Belongs to the thiolase family
BS1321_RS14315	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS14320	COG1393	Belongs to the ArsC family
BS1321_RS14325	COG0509	glycine decarboxylation via glycine cleavage system
BS1321_RS14330	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BS1321_RS14335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS14340	COG2873	o-acetylhomoserine
BS1321_RS14345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS1321_RS14350	COG2011	ABC-type metal ion transport system permease component
BS1321_RS14355	COG1464	Belongs to the NlpA lipoprotein family
BS1321_RS14365	COG0396	ATPase activity
BS1321_RS14370	COG0719	Fe-S assembly protein
BS1321_RS14375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BS1321_RS14380	COG0822	iron-sulfur transferase activity
BS1321_RS14385	COG0719	Fe-S assembly protein
BS1321_RS14390	COG1801	Protein of unknown function DUF72
BS1321_RS14395	COG0730	response to heat
BS1321_RS14400	COG0737	Belongs to the 5'-nucleotidase family
BS1321_RS14405	COG3377	Domain of unknown function (DUF1805)
BS1321_RS14420	COG0739	heme binding
BS1321_RS14425	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BS1321_RS14435	COG4470	Protein conserved in bacteria
BS1321_RS14450	COG2445	Protein of unknown function DUF86
BS1321_RS14455	COG0647	UMP catabolic process
BS1321_RS14460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BS1321_RS14465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS1321_RS14475	COG0460	homoserine dehydrogenase
BS1321_RS14480	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS1321_RS14485	COG0083	homoserine kinase activity
BS1321_RS14490	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BS1321_RS14495	COG4837	Protein of unknown function (DUF1462)
BS1321_RS14500	COG1252	NADH dehydrogenase
BS1321_RS14520	COG0316	Belongs to the HesB IscA family
BS1321_RS14530	COG0492	ferredoxin-NADP+ reductase activity
BS1321_RS14535	COG1252	NADH dehydrogenase
BS1321_RS14550	COG3584	3D domain protein
BS1321_RS14560	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
BS1321_RS14565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BS1321_RS14580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS1321_RS14580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BS1321_RS14595	COG2050	protein possibly involved in aromatic compounds catabolism
BS1321_RS14605	COG1320	monovalent cation:proton antiporter activity
BS1321_RS14610	COG2212	antiporter activity
BS1321_RS14615	COG1863	multisubunit Na H antiporter MnhE subunit
BS1321_RS14620	COG0651	ATP synthesis coupled electron transport
BS1321_RS14625	COG1006	Multisubunit Na H antiporter MnhC subunit
BS1321_RS14630	COG2111	Na H antiporter
BS1321_RS14635	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BS1321_RS14635	COG2111	Na H antiporter
BS1321_RS14645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS1321_RS14650	COG5018	Exonuclease
BS1321_RS14660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS1321_RS14670	COG0456	acetyltransferase
BS1321_RS14685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS1321_RS14690	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BS1321_RS14700	COG2267	carboxylic ester hydrolase activity
BS1321_RS14705	COG1522	sequence-specific DNA binding
BS1321_RS14710	COG0436	Aminotransferase
BS1321_RS14720	COG0733	neurotransmitter:sodium symporter activity
BS1321_RS14725	COG1098	S1 RNA binding domain
BS1321_RS14730	COG2155	Conserved Protein
BS1321_RS14735	COG1979	alcohol dehydrogenase
BS1321_RS14755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BS1321_RS14760	COG3858	chitin binding
BS1321_RS14760	COG1388	LysM domain
BS1321_RS14770	COG0584	glycerophosphoryl diester phosphodiesterase
BS1321_RS14775	COG1968	undecaprenyl-diphosphatase activity
BS1321_RS14780	COG0531	amino acid
BS1321_RS14785	COG2814	Major facilitator Superfamily
BS1321_RS14815	COG1191	sigma factor activity
BS1321_RS14830	COG2318	DinB family
BS1321_RS14835	COG0737	Belongs to the 5'-nucleotidase family
BS1321_RS14850	COG1113	amino acid transport
BS1321_RS14855	COG2356	endonuclease I
BS1321_RS14860	COG1950	PFAM Membrane protein of
BS1321_RS14870	COG0753	catalase activity
BS1321_RS14890	COG0196	riboflavin kinase activity
BS1321_RS14895	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BS1321_RS14900	COG1785	Belongs to the alkaline phosphatase family
BS1321_RS14915	COG0322	excinuclease ABC activity
BS1321_RS14920	COG0523	cobalamin synthesis protein
BS1321_RS14925	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS1321_RS14930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BS1321_RS14935	COG0346	lactoylglutathione lyase activity
BS1321_RS14940	COG3906	Belongs to the UPF0473 family
BS1321_RS14945	COG3773	Cell wall hydrolase
BS1321_RS14950	COG4191	Histidine kinase
BS1321_RS14955	COG0604	alcohol dehydrogenase
BS1321_RS14960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BS1321_RS15000	COG0833	amino acid
BS1321_RS15005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BS1321_RS15010	COG1994	Peptidase M50
BS1321_RS15015	COG2814	Major facilitator Superfamily
BS1321_RS15020	COG0640	Transcriptional regulator
BS1321_RS15025	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BS1321_RS15035	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
BS1321_RS15040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BS1321_RS15050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BS1321_RS15060	COG2508	Transcriptional regulator
BS1321_RS15065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS15070	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS15075	COG0506	proline dehydrogenase activity
BS1321_RS15085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS15110	COG1285	pathogenesis
BS1321_RS15245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BS1321_RS15250	COG1575	Belongs to the MenA family. Type 1 subfamily
BS1321_RS15255	COG1169	isochorismate synthase
BS1321_RS15260	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BS1321_RS15265	COG0596	Alpha beta hydrolase
BS1321_RS15270	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BS1321_RS15275	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS15280	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS15290	COG4565	transcriptional regulatory protein
BS1321_RS15295	COG3290	protein histidine kinase activity
BS1321_RS15300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BS1321_RS15305	COG3443	Belongs to the bacterial solute-binding protein 9 family
BS1321_RS15305	COG0803	Belongs to the bacterial solute-binding protein 9 family
BS1321_RS15310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BS1321_RS15315	COG1854	S-ribosylhomocysteine lyase activity
BS1321_RS15325	COG0783	Belongs to the Dps family
BS1321_RS15345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS1321_RS15350	COG1116	anion transmembrane transporter activity
BS1321_RS15355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS1321_RS15360	COG1506	peptidase
BS1321_RS15370	COG1683	Conserved Protein
BS1321_RS15390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BS1321_RS15415	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BS1321_RS15420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BS1321_RS15425	COG2267	carboxylic ester hydrolase activity
BS1321_RS15435	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BS1321_RS15440	COG1242	4 iron, 4 sulfur cluster binding
BS1321_RS15455	COG0495	leucyl-tRNA aminoacylation
BS1321_RS15460	COG1404	Belongs to the peptidase S8 family
BS1321_RS15485	COG1131	(ABC) transporter
BS1321_RS15500	COG5577	PFAM Coat F domain
BS1321_RS15505	COG0583	DNA-binding transcription factor activity
BS1321_RS15510	COG0069	glutamate synthase activity
BS1321_RS15510	COG0070	glutamate synthase
BS1321_RS15510	COG0067	glutamate synthase
BS1321_RS15515	COG0493	'glutamate synthase
BS1321_RS15520	COG2079	MmgE PrpD family protein
BS1321_RS15525	COG1126	abc transporter atp-binding protein
BS1321_RS15530	COG0765	amino acid transport
BS1321_RS15535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS15540	COG0456	acetyltransferase
BS1321_RS15545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS15550	COG1473	amidohydrolase
BS1321_RS15570	COG5566	PFAM Mor transcription activator
BS1321_RS15575	COG0702	epimerase
BS1321_RS15580	COG0110	maltose O-acetyltransferase activity
BS1321_RS15585	COG1114	Component of the transport system for branched-chain amino acids
BS1321_RS15590	COG0714	Associated with various cellular activities
BS1321_RS15595	COG4548	von Willebrand factor, type A
BS1321_RS15615	COG1288	antiporter activity
BS1321_RS15630	COG3192	ethanolamine utilization protein
BS1321_RS15640	COG4303	Ethanolamine ammonia lyase large subunit
BS1321_RS15645	COG4302	ethanolamine ammonia-lyase activity
BS1321_RS15660	COG0726	polysaccharide deacetylase
BS1321_RS15665	COG1595	DNA-templated transcription, initiation
BS1321_RS15680	COG3104	oligopeptide transport
BS1321_RS15710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS1321_RS15715	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BS1321_RS15725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BS1321_RS15735	COG0586	Pfam SNARE associated Golgi protein
BS1321_RS15740	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BS1321_RS15745	COG1910	domain protein
BS1321_RS15750	COG0725	ABC transporter, periplasmic molybdate-binding protein
BS1321_RS15765	COG0456	acetyltransferase
BS1321_RS15765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS1321_RS15770	COG1609	Transcriptional regulator
BS1321_RS15775	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS15780	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BS1321_RS15785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS15795	COG0456	acetyltransferase
BS1321_RS15795	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BS1321_RS15815	COG1131	(ABC) transporter
BS1321_RS15830	COG2814	Major facilitator Superfamily
BS1321_RS15845	COG0346	lactoylglutathione lyase activity
BS1321_RS15880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS15885	COG1959	2 iron, 2 sulfur cluster binding
BS1321_RS15890	COG1511	domain protein
BS1321_RS15895	COG0640	Transcriptional regulator
BS1321_RS15900	COG3832	glyoxalase III activity
BS1321_RS15910	COG2112	serine threonine protein kinase
BS1321_RS15915	COG4193	domain, Protein
BS1321_RS15920	COG1959	2 iron, 2 sulfur cluster binding
BS1321_RS15925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BS1321_RS15930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BS1321_RS15935	COG2910	NAD(P)H-binding
BS1321_RS15940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS1321_RS15945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS1321_RS15950	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BS1321_RS15950	COG0463	Glycosyl transferase, family 2
BS1321_RS15955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BS1321_RS15965	COG0384	phenazine biosynthesis protein PhzF
BS1321_RS15980	COG2226	methyltransferase
BS1321_RS15985	COG3615	Tellurite resistance protein tehB
BS1321_RS15985	COG0500	methyltransferase
BS1321_RS15990	COG1366	Belongs to the anti-sigma-factor antagonist family
BS1321_RS15995	COG0569	domain protein
BS1321_RS16000	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BS1321_RS16035	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS1321_RS16040	COG2188	Transcriptional regulator
BS1321_RS16045	COG1388	LysM domain
BS1321_RS16045	COG3858	chitin binding
BS1321_RS16050	COG0384	phenazine biosynthesis protein PhzF
BS1321_RS16055	COG1309	transcriptional regulator
BS1321_RS16060	COG1131	(ABC) transporter
BS1321_RS16065	COG3559	Exporter of polyketide antibiotics
BS1321_RS16080	COG1396	sequence-specific DNA binding
BS1321_RS16085	COG0737	Belongs to the 5'-nucleotidase family
BS1321_RS16095	COG1760	l-serine dehydratase
BS1321_RS16100	COG1760	l-serine dehydratase
BS1321_RS16110	COG1114	Component of the transport system for branched-chain amino acids
BS1321_RS16125	COG1073	alpha beta
BS1321_RS16130	COG1309	transcriptional regulator
BS1321_RS16140	COG0531	amino acid
BS1321_RS16170	COG3773	Cell wall hydrolase
BS1321_RS16190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BS1321_RS16205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BS1321_RS16250	COG0789	Transcriptional regulator
BS1321_RS16255	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS16265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS1321_RS16270	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS16275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BS1321_RS16290	COG2720	vancomycin resistance protein
BS1321_RS16300	COG3848	Pyruvate phosphate dikinase
BS1321_RS16300	COG0574	Belongs to the PEP-utilizing enzyme family
BS1321_RS16305	COG0640	Transcriptional regulator
BS1321_RS16310	COG0346	lactoylglutathione lyase activity
BS1321_RS16320	COG1335	isochorismatase
BS1321_RS16365	COG2364	Membrane
BS1321_RS16370	COG1846	Transcriptional regulator
BS1321_RS16375	COG0456	acetyltransferase
BS1321_RS16385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS16400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS16410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS16415	COG2808	Putative FMN-binding domain
BS1321_RS16420	COG1525	nuclease
BS1321_RS16420	COG4085	toxin activity
BS1321_RS16420	COG0737	Belongs to the 5'-nucleotidase family
BS1321_RS16425	COG0024	Methionine aminopeptidase
BS1321_RS16460	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS16500	COG1301	dicarboxylic acid transport
BS1321_RS16515	COG0772	Belongs to the SEDS family
BS1321_RS16520	COG1695	Transcriptional regulator
BS1321_RS16545	COG1404	Belongs to the peptidase S8 family
BS1321_RS16615	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS1321_RS16620	COG0604	alcohol dehydrogenase
BS1321_RS16620	COG3321	synthase
BS1321_RS16620	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS16625	COG1733	regulation of RNA biosynthetic process
BS1321_RS16655	COG0456	acetyltransferase
BS1321_RS16660	COG1757	Na H antiporter
BS1321_RS16665	COG0686	Belongs to the AlaDH PNT family
BS1321_RS16670	COG3829	transcription factor binding
BS1321_RS16690	COG1794	racemase activity, acting on amino acids and derivatives
BS1321_RS16700	COG2070	2-Nitropropane dioxygenase
BS1321_RS16705	COG0477	Major facilitator Superfamily
BS1321_RS16710	COG1942	4-Oxalocrotonate Tautomerase
BS1321_RS16715	COG0583	DNA-binding transcription factor activity
BS1321_RS16730	COG1846	Transcriptional regulator
BS1321_RS16735	COG1819	glycosyl
BS1321_RS16770	COG0346	lactoylglutathione lyase activity
BS1321_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS16800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS1321_RS16805	COG1247	-acetyltransferase
BS1321_RS16810	COG3584	3D domain protein
BS1321_RS16810	COG1388	LysM domain
BS1321_RS16815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BS1321_RS16830	COG1131	(ABC) transporter
BS1321_RS16835	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS1321_RS16865	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
BS1321_RS16870	COG0583	DNA-binding transcription factor activity
BS1321_RS16875	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS16880	COG0697	spore germination
BS1321_RS16885	COG0791	NLP P60 protein
BS1321_RS16885	COG1388	LysM domain
BS1321_RS16890	COG2318	DinB family
BS1321_RS16900	COG3239	Fatty acid desaturase
BS1321_RS16905	COG2197	response regulator
BS1321_RS16910	COG0018	arginyl-trna synthetase
BS1321_RS16915	COG1609	Transcriptional regulator
BS1321_RS16925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BS1321_RS16935	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BS1321_RS16940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BS1321_RS16945	COG1252	NADH dehydrogenase
BS1321_RS16955	COG0047	phosphoribosylformylglycinamidine synthase activity
BS1321_RS16960	COG1522	sequence-specific DNA binding
BS1321_RS16970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS1321_RS17000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BS1321_RS17010	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS1321_RS17020	COG2207	Transcriptional regulator
BS1321_RS17025	COG2972	Histidine kinase
BS1321_RS17030	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS17035	COG0444	Belongs to the ABC transporter superfamily
BS1321_RS17045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS17050	COG0747	negative chemotaxis
BS1321_RS17055	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS17070	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS17075	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS17080	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS17085	COG2233	PERMEase
BS1321_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS17130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS17150	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BS1321_RS17155	COG1263	PTS System
BS1321_RS17155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS17155	COG2190	(PTS) system
BS1321_RS17175	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS1321_RS17180	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS1321_RS17185	COG3842	ATPase activity
BS1321_RS17190	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BS1321_RS17195	COG1193	negative regulation of DNA recombination
BS1321_RS17200	COG0697	spore germination
BS1321_RS17205	COG0583	DNA-binding transcription factor activity
BS1321_RS17210	COG0583	DNA-binding transcription factor activity
BS1321_RS17220	COG0582	viral genome integration into host DNA
BS1321_RS17230	COG1473	amidohydrolase
BS1321_RS17235	COG1288	antiporter activity
BS1321_RS17240	COG1595	DNA-templated transcription, initiation
BS1321_RS17245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS1321_RS17255	COG0393	Putative heavy-metal-binding
BS1321_RS17260	COG2909	trisaccharide binding
BS1321_RS17275	COG3275	phosphorelay sensor kinase activity
BS1321_RS17280	COG3279	Response regulator of the LytR AlgR family
BS1321_RS17285	COG1966	Carbon starvation protein
BS1321_RS17295	COG4122	O-methyltransferase activity
BS1321_RS17305	COG1309	transcriptional regulator
BS1321_RS17310	COG0477	Major facilitator Superfamily
BS1321_RS17330	COG1335	isochorismatase
BS1321_RS17335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS1321_RS17355	COG0561	phosphatase activity
BS1321_RS17360	COG1609	Transcriptional regulator
BS1321_RS17365	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS17370	COG1454	alcohol dehydrogenase
BS1321_RS17375	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS17400	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BS1321_RS17415	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BS1321_RS17420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS17425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BS1321_RS17430	COG1120	ATPase activity
BS1321_RS17435	COG2140	Oxalate decarboxylase
BS1321_RS17445	COG0402	S-adenosylhomocysteine deaminase activity
BS1321_RS17465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BS1321_RS17470	COG2011	ABC-type metal ion transport system permease component
BS1321_RS17475	COG1464	Belongs to the NlpA lipoprotein family
BS1321_RS17495	COG0412	Dienelactone hydrolase
BS1321_RS17530	COG1694	Mazg nucleotide pyrophosphohydrolase
BS1321_RS17545	COG1051	belongs to the nudix hydrolase family
BS1321_RS17580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS17585	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BS1321_RS17590	COG1687	branched-chain amino acid
BS1321_RS17605	COG3048	D-serine ammonia-lyase activity
BS1321_RS17620	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS1321_RS17690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BS1321_RS17695	COG0384	phenazine biosynthesis protein PhzF
BS1321_RS17700	COG0745	RESPONSE REGULATOR receiver
BS1321_RS17705	COG5002	protein histidine kinase activity
BS1321_RS17705	COG3850	Histidine kinase
BS1321_RS17715	COG0288	reversible hydration of carbon dioxide
BS1321_RS17720	COG0659	secondary active sulfate transmembrane transporter activity
BS1321_RS17725	COG2602	Beta-lactamase
BS1321_RS17765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BS1321_RS17770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS1321_RS17805	COG1914	H( )-stimulated, divalent metal cation uptake system
BS1321_RS17815	COG1027	Aspartate ammonia-lyase
BS1321_RS17825	COG4191	Histidine kinase
BS1321_RS17830	COG0784	Response regulator, receiver
BS1321_RS17840	COG3973	AAA domain
BS1321_RS17855	COG2205	protein histidine kinase activity
BS1321_RS17880	COG0477	Major facilitator Superfamily
BS1321_RS17895	COG2819	hydrolase of the alpha beta superfamily
BS1321_RS17910	COG1464	Belongs to the NlpA lipoprotein family
BS1321_RS17915	COG5444	nuclease activity
BS1321_RS18010	COG1061	Type III restriction enzyme res subunit
BS1321_RS18035	COG1376	ErfK ybiS ycfS ynhG family protein
BS1321_RS18060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BS1321_RS18075	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS1321_RS18100	COG0583	DNA-binding transcription factor activity
BS1321_RS18135	COG3011	Protein conserved in bacteria
BS1321_RS18140	COG3594	Acyltransferase
BS1321_RS18145	COG1686	Belongs to the peptidase S11 family
BS1321_RS18155	COG3773	Cell wall hydrolase
BS1321_RS18170	COG4257	antibiotic catabolic process
BS1321_RS18200	COG3708	Transcriptional regulator
BS1321_RS18200	COG2207	Transcriptional regulator
BS1321_RS18245	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS18250	COG1250	3-hydroxyacyl-CoA dehydrogenase
BS1321_RS18255	COG0183	Belongs to the thiolase family
BS1321_RS18260	COG3290	protein histidine kinase activity
BS1321_RS18260	COG3829	transcription factor binding
BS1321_RS18270	COG2610	gluconate transmembrane transporter activity
BS1321_RS18275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS1321_RS18280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS1321_RS18285	COG1876	peptidase activity
BS1321_RS18295	COG3829	transcription factor binding
BS1321_RS18300	COG1509	lysine 2,3-aminomutase activity
BS1321_RS18315	COG1141	Ferredoxin
BS1321_RS18320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS1321_RS18325	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS1321_RS18330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS1321_RS18335	COG0183	Belongs to the thiolase family
BS1321_RS18340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS1321_RS18360	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS1321_RS18365	COG1280	lysine exporter protein (LysE YggA)
BS1321_RS18370	COG2814	Major facilitator Superfamily
BS1321_RS18375	COG1113	amino acid transport
BS1321_RS18380	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BS1321_RS18385	COG1309	transcriptional regulator
BS1321_RS18390	COG2814	Major facilitator Superfamily
BS1321_RS18395	COG1511	domain protein
BS1321_RS18400	COG0583	DNA-binding transcription factor activity
BS1321_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS18420	COG2186	Transcriptional regulator
BS1321_RS18430	COG2271	Major facilitator Superfamily
BS1321_RS18435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS1321_RS18440	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS18450	COG2271	Major facilitator Superfamily
BS1321_RS18455	COG2721	sulfolactate sulfo-lyase activity
BS1321_RS18485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BS1321_RS18495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BS1321_RS18500	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS1321_RS18505	COG0778	Nitroreductase
BS1321_RS18510	COG0716	FMN binding
BS1321_RS18530	COG3647	Membrane
BS1321_RS18535	COG0596	Alpha beta hydrolase
BS1321_RS18550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS1321_RS18565	COG1280	lysine exporter protein (LysE YggA)
BS1321_RS18570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BS1321_RS18575	COG3483	tryptophan 2,3-dioxygenase activity
BS1321_RS18580	COG1113	amino acid transport
BS1321_RS18585	COG3844	kynureninase activity
BS1321_RS18610	COG4585	Histidine kinase
BS1321_RS18615	COG2197	response regulator
BS1321_RS18635	COG1113	amino acid transport
BS1321_RS18645	COG1823	symporter activity
BS1321_RS18660	COG3290	protein histidine kinase activity
BS1321_RS18665	COG4565	transcriptional regulatory protein
BS1321_RS18670	COG2851	Citrate transporter
BS1321_RS18680	COG1357	PFAM Pentapeptide repeats (8 copies)
BS1321_RS18685	COG0789	Transcriptional regulator
BS1321_RS18690	COG2890	protein-(glutamine-N5) methyltransferase activity
BS1321_RS18700	COG3142	Participates in the control of copper homeostasis
BS1321_RS18710	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BS1321_RS18725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BS1321_RS18730	COG2169	Transcriptional regulator
BS1321_RS18735	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BS1321_RS18750	COG3290	protein histidine kinase activity
BS1321_RS18755	COG4565	transcriptional regulatory protein
BS1321_RS18760	COG2851	Citrate transporter
BS1321_RS18765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS1321_RS18765	COG2213	PTS system mannitol-specific
BS1321_RS18770	COG3711	transcriptional antiterminator
BS1321_RS18775	COG0246	Mannitol dehydrogenase
BS1321_RS18785	COG0601	transmembrane transport
BS1321_RS18795	COG0444	Belongs to the ABC transporter superfamily
BS1321_RS18800	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS18805	COG0534	Mate efflux family protein
BS1321_RS18815	COG2259	Doxx family
BS1321_RS18820	COG2514	catechol 2,3-dioxygenase activity
BS1321_RS18830	COG3829	transcription factor binding
BS1321_RS18835	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS18840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BS1321_RS18845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS1321_RS18870	COG0671	phosphoesterase, PA-phosphatase related
BS1321_RS18875	COG0586	Pfam SNARE associated Golgi protein
BS1321_RS18880	COG0697	spore germination
BS1321_RS18890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS18900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS1321_RS18910	COG3655	Transcriptional regulator
BS1321_RS18915	COG3739	integral membrane protein
BS1321_RS18920	COG2076	Multidrug Resistance protein
BS1321_RS18925	COG2076	Multidrug Resistance protein
BS1321_RS18930	COG0697	spore germination
BS1321_RS18935	COG2002	toxin-antitoxin pair type II binding
BS1321_RS18940	COG0456	acetyltransferase
BS1321_RS18960	COG2318	DinB family
BS1321_RS18990	COG1388	LysM domain
BS1321_RS18990	COG0791	NLP P60 protein
BS1321_RS18995	COG4195	phage-related replication protein
BS1321_RS19030	COG0720	synthase
BS1321_RS19045	COG1309	transcriptional regulator
BS1321_RS19055	COG1078	dGTPase activity
BS1321_RS19075	COG1695	Transcriptional regulator
BS1321_RS19080	COG1647	Serine aminopeptidase, S33
BS1321_RS19090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BS1321_RS19105	COG1733	regulation of RNA biosynthetic process
BS1321_RS19110	COG2814	Major facilitator Superfamily
BS1321_RS19115	COG0656	L-ascorbic acid biosynthetic process
BS1321_RS19120	COG1902	pentaerythritol trinitrate reductase activity
BS1321_RS19125	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS1321_RS19130	COG0473	3-isopropylmalate dehydrogenase activity
BS1321_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS19155	COG2081	HI0933 family
BS1321_RS19160	COG2244	polysaccharide biosynthetic process
BS1321_RS19165	COG1187	pseudouridine synthase activity
BS1321_RS19170	COG1349	DNA-binding transcription factor activity
BS1321_RS19180	COG1349	DNA-binding transcription factor activity
BS1321_RS19210	COG0531	amino acid
BS1321_RS19220	COG2508	Transcriptional regulator
BS1321_RS19225	COG0492	ferredoxin-NADP+ reductase activity
BS1321_RS19230	COG0577	efflux transmembrane transporter activity
BS1321_RS19235	COG1136	(ABC) transporter
BS1321_RS19240	COG0642	Histidine kinase
BS1321_RS19245	COG0745	RESPONSE REGULATOR receiver
BS1321_RS19250	COG2824	Alkylphosphonate utilization operon protein PhnA
BS1321_RS19260	COG0613	PHP domain protein
BS1321_RS19285	COG3627	carbon phosphorus lyase activity
BS1321_RS19290	COG4107	phosphonate C-P lyase system protein PhnK
BS1321_RS19295	COG3454	Phosphonate metabolism
BS1321_RS19300	COG4778	phosphonate C-P lyase system protein PhnL
BS1321_RS19310	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BS1321_RS19315	COG3639	organic phosphonate transmembrane transporter activity
BS1321_RS19320	COG3639	organic phosphonate transmembrane transporter activity
BS1321_RS19335	COG0701	Predicted permease
BS1321_RS19345	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS19350	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BS1321_RS19355	COG0697	spore germination
BS1321_RS19365	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BS1321_RS19375	COG1587	Uroporphyrinogen-III synthase
BS1321_RS19380	COG1587	Uroporphyrinogen-III synthase
BS1321_RS19380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BS1321_RS19410	COG0586	Pfam SNARE associated Golgi protein
BS1321_RS19420	COG0534	Mate efflux family protein
BS1321_RS19425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS1321_RS19440	COG1914	H( )-stimulated, divalent metal cation uptake system
BS1321_RS19455	COG1597	lipid kinase activity
BS1321_RS19460	COG0510	thiamine kinase activity
BS1321_RS19470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BS1321_RS19475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS19485	COG1363	Peptidase, m42
BS1321_RS19490	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BS1321_RS19495	COG2207	Transcriptional regulator
BS1321_RS19495	COG3708	Transcriptional regulator
BS1321_RS19510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS19515	COG4848	Belongs to the UPF0354 family
BS1321_RS19520	COG1473	amidohydrolase
BS1321_RS19525	COG1674	ftsk spoiiie
BS1321_RS19530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BS1321_RS19535	COG2309	aminopeptidase activity
BS1321_RS19540	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BS1321_RS19545	COG4980	gas vesicle protein
BS1321_RS19550	COG3118	belongs to the thioredoxin family
BS1321_RS19555	COG1605	Chorismate mutase
BS1321_RS19555	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BS1321_RS19560	COG1609	Transcriptional regulator
BS1321_RS19565	COG0123	including yeast histone deacetylase and acetoin utilization protein
BS1321_RS19570	COG0517	IMP dehydrogenase activity
BS1321_RS19575	COG0454	-acetyltransferase
BS1321_RS19580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS1321_RS19595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BS1321_RS19600	COG1956	GAF domain-containing protein
BS1321_RS19605	COG1309	transcriptional regulator
BS1321_RS19610	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS1321_RS19615	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BS1321_RS19620	COG1104	cysteine desulfurase activity
BS1321_RS19625	COG0301	tRNA thio-modification
BS1321_RS19635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS1321_RS19640	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BS1321_RS19645	COG2962	Rard protein
BS1321_RS19655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BS1321_RS19665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BS1321_RS19675	COG0084	hydrolase, TatD family'
BS1321_RS19680	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BS1321_RS19700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BS1321_RS19705	COG0616	signal peptide processing
BS1321_RS19710	COG1714	RDD family
BS1321_RS19720	COG3874	Sporulation protein YtfJ
BS1321_RS19725	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BS1321_RS19735	COG0827	DNA restriction-modification system
BS1321_RS19740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BS1321_RS19750	COG0521	Mo-molybdopterin cofactor biosynthetic process
BS1321_RS19760	COG0137	argininosuccinate synthase activity
BS1321_RS19765	COG0165	Argininosuccinate lyase
BS1321_RS19770	COG0589	response to stress
BS1321_RS19775	COG0006	proline dipeptidase activity
BS1321_RS19780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BS1321_RS19790	COG4109	DRTGG domain
BS1321_RS19800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BS1321_RS19815	COG0587	DNA-directed DNA polymerase activity
BS1321_RS19820	COG0281	malic enzyme
BS1321_RS19825	COG2186	Transcriptional regulator
BS1321_RS19830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BS1321_RS19835	COG0825	malonyl-CoA metabolic process
BS1321_RS19840	COG0205	6-phosphofructokinase activity
BS1321_RS19855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BS1321_RS19860	COG2224	Isocitrate lyase
BS1321_RS19865	COG0628	permease
BS1321_RS19870	COG2707	UPF0756 membrane protein
BS1321_RS19875	COG0372	Belongs to the citrate synthase family
BS1321_RS19880	COG0538	isocitrate dehydrogenase activity
BS1321_RS19890	COG0745	RESPONSE REGULATOR receiver
BS1321_RS19895	COG5002	protein histidine kinase activity
BS1321_RS19900	COG0330	HflC and HflK could
BS1321_RS19905	COG0330	HflC and HflK could
BS1321_RS19910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS1321_RS19910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS1321_RS19915	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BS1321_RS19920	COG1971	Probably functions as a manganese efflux pump
BS1321_RS19925	COG0237	dephospho-CoA kinase activity
BS1321_RS19930	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BS1321_RS19935	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS1321_RS19940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BS1321_RS19945	COG3611	Membrane attachment protein
BS1321_RS19950	COG1484	DNA-dependent DNA replication
BS1321_RS19960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BS1321_RS19965	COG0456	acetyltransferase
BS1321_RS19970	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BS1321_RS19980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BS1321_RS19985	COG3326	Membrane
BS1321_RS20005	COG1363	Peptidase, m42
BS1321_RS20010	COG1556	Lactate utilization protein
BS1321_RS20015	COG1139	Iron-sulfur cluster binding protein
BS1321_RS20020	COG0247	lactate metabolic process
BS1321_RS20025	COG2186	Transcriptional regulator
BS1321_RS20030	COG1620	l-lactate permease
BS1321_RS20035	COG3835	regulator
BS1321_RS20040	COG0277	FAD linked oxidase domain protein
BS1321_RS20045	COG0247	lactate metabolic process
BS1321_RS20050	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
BS1321_RS20075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BS1321_RS20080	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BS1321_RS20085	COG0072	phenylalanine-tRNA ligase activity
BS1321_RS20085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BS1321_RS20090	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BS1321_RS20095	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BS1321_RS20100	COG1286	toxin biosynthetic process
BS1321_RS20105	COG1796	DNA polymerase
BS1321_RS20105	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BS1321_RS20110	COG1193	negative regulation of DNA recombination
BS1321_RS20115	COG3766	membrane
BS1321_RS20125	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS20130	COG1309	transcriptional regulator
BS1321_RS20135	COG1024	Enoyl-CoA hydratase
BS1321_RS20140	COG2086	electron transfer activity
BS1321_RS20145	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BS1321_RS20150	COG3118	belongs to the thioredoxin family
BS1321_RS20165	COG1719	4-vinyl reductase, 4VR
BS1321_RS20170	COG2009	succinate dehydrogenase
BS1321_RS20175	COG1053	succinate dehydrogenase
BS1321_RS20180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BS1321_RS20185	COG0824	Thioesterase
BS1321_RS20190	COG2197	response regulator
BS1321_RS20195	COG1846	Transcriptional regulator
BS1321_RS20210	COG5401	PFAM Sporulation and spore germination
BS1321_RS20230	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BS1321_RS20235	COG0622	Phosphoesterase
BS1321_RS20325	COG0028	Belongs to the TPP enzyme family
BS1321_RS20330	COG0440	acetolactate synthase activity
BS1321_RS20335	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BS1321_RS20340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS1321_RS20345	COG0473	3-isopropylmalate dehydrogenase activity
BS1321_RS20350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BS1321_RS20355	COG0066	3-isopropylmalate dehydratase activity
BS1321_RS20365	COG0544	peptidyl-prolyl cis-trans isomerase activity
BS1321_RS20375	COG1067	ATP-dependent peptidase activity
BS1321_RS20375	COG0470	DNA polymerase III
BS1321_RS20380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BS1321_RS20385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BS1321_RS20400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS1321_RS20405	COG0181	hydroxymethylbilane synthase activity
BS1321_RS20415	COG0113	porphobilinogen synthase activity
BS1321_RS20420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BS1321_RS20425	COG1388	LysM domain
BS1321_RS20430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BS1321_RS20445	COG0525	valine-tRNA ligase activity
BS1321_RS20450	COG0189	ligase activity
BS1321_RS20455	COG0189	ligase activity
BS1321_RS20460	COG0285	dihydrofolate synthase activity
BS1321_RS20465	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BS1321_RS20480	COG2003	Belongs to the UPF0758 family
BS1321_RS20485	COG1077	Cell shape determining protein MreB Mrl
BS1321_RS20490	COG1792	Involved in formation and maintenance of cell shape
BS1321_RS20500	COG0850	regulation of cytokinetic process
BS1321_RS20505	COG2894	cell division
BS1321_RS20510	COG1098	S1 RNA binding domain
BS1321_RS20515	COG0739	heme binding
BS1321_RS20520	COG1994	Peptidase M50
BS1321_RS20525	COG1530	ribonuclease E activity
BS1321_RS20530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BS1321_RS20535	COG2868	ribosomal protein
BS1321_RS20545	COG3290	protein histidine kinase activity
BS1321_RS20550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BS1321_RS20555	COG4492	Belongs to the UPF0735 family
BS1321_RS20560	COG0077	Prephenate dehydratase
BS1321_RS20570	COG1827	regulation of RNA biosynthetic process
BS1321_RS20575	COG1104	cysteine desulfurase activity
BS1321_RS20580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BS1321_RS20585	COG0157	Belongs to the NadC ModD family
BS1321_RS20595	COG2321	neutral zinc metallopeptidase
BS1321_RS20620	COG0632	four-way junction helicase activity
BS1321_RS20635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BS1321_RS20640	COG0343	queuine tRNA-ribosyltransferase activity
BS1321_RS20645	COG1862	Preprotein translocase
BS1321_RS20655	COG2323	membrane
BS1321_RS20660	COG2244	polysaccharide biosynthetic process
BS1321_RS20670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS1321_RS20670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BS1321_RS20675	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BS1321_RS20675	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BS1321_RS20680	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS1321_RS20685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BS1321_RS20690	COG1490	D-aminoacyl-tRNA deacylase activity
BS1321_RS20695	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS1321_RS20695	COG3103	Sh3 type 3 domain protein
BS1321_RS20695	COG4991	sh3 domain protein
BS1321_RS20700	COG0124	histidyl-tRNA synthetase
BS1321_RS20705	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BS1321_RS20725	COG1116	anion transmembrane transporter activity
BS1321_RS20745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BS1321_RS20765	COG0411	ABC transporter
BS1321_RS20790	COG0411	ABC transporter
BS1321_RS20820	COG2814	Major facilitator Superfamily
BS1321_RS20835	COG3944	biosynthesis protein
BS1321_RS20840	COG0489	protein tyrosine kinase activity
BS1321_RS20845	COG4464	protein tyrosine phosphatase activity
BS1321_RS20855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS1321_RS20860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BS1321_RS20870	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS20880	COG1215	transferase activity, transferring glycosyl groups
BS1321_RS20890	COG1045	serine acetyltransferase
BS1321_RS20950	COG1132	(ABC) transporter
BS1321_RS20960	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BS1321_RS20980	COG1316	TRANSCRIPTIONal
BS1321_RS20985	COG1131	(ABC) transporter
BS1321_RS21000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BS1321_RS21005	COG1959	2 iron, 2 sulfur cluster binding
BS1321_RS21010	COG1104	cysteine desulfurase activity
BS1321_RS21015	COG0482	sulfurtransferase activity
BS1321_RS21025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BS1321_RS21030	COG1704	LemA family
BS1321_RS21040	COG3881	PFAM PRC-barrel domain
BS1321_RS21050	COG0628	permease
BS1321_RS21065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BS1321_RS21070	COG3906	Belongs to the UPF0473 family
BS1321_RS21075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BS1321_RS21080	COG4122	O-methyltransferase activity
BS1321_RS21085	COG0826	peptidase U32
BS1321_RS21090	COG0826	peptidase U32
BS1321_RS21095	COG0572	uridine kinase
BS1321_RS21100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BS1321_RS21105	COG0768	penicillin binding
BS1321_RS21120	COG2226	methyltransferase
BS1321_RS21130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BS1321_RS21135	COG0626	cystathionine gamma-synthase activity
BS1321_RS21170	COG1183	phosphatidylcholine synthase activity
BS1321_RS21175	COG0688	phosphatidylethanolamine metabolic process
BS1321_RS21185	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BS1321_RS21190	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BS1321_RS21200	COG1534	Rna-binding protein
BS1321_RS21205	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BS1321_RS21210	COG1713	HD superfamily hydrolase involved in NAD metabolism
BS1321_RS21215	COG0799	negative regulation of ribosome biogenesis
BS1321_RS21220	COG2226	methyltransferase
BS1321_RS21225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS1321_RS21230	COG1555	photosystem II stabilization
BS1321_RS21230	COG1596	polysaccharide export
BS1321_RS21235	COG2131	deaminase
BS1321_RS21240	COG0658	competence protein
BS1321_RS21240	COG2333	competence protein COMEC
BS1321_RS21250	COG1466	dna polymerase III delta subunit
BS1321_RS21255	COG0268	Binds directly to 16S ribosomal RNA
BS1321_RS21265	COG0860	N-Acetylmuramoyl-L-alanine amidase
BS1321_RS21280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BS1321_RS21285	COG1420	regulation of RNA biosynthetic process
BS1321_RS21290	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BS1321_RS21295	COG0443	Heat shock 70 kDa protein
BS1321_RS21305	COG2264	protein methyltransferase activity
BS1321_RS21310	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BS1321_RS21315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BS1321_RS21320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BS1321_RS21330	COG1283	sodium-dependent phosphate transmembrane transporter activity
BS1321_RS21335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BS1321_RS21340	COG1610	YqeY-like protein
BS1321_RS21345	COG1030	water channel activity
BS1321_RS21350	COG4864	UPF0365 protein
BS1321_RS21370	COG1702	phosphate starvation-inducible protein PhoH
BS1321_RS21375	COG1480	7TM receptor with intracellular HD hydrolase
BS1321_RS21385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BS1321_RS21390	COG0295	cytidine deaminase activity
BS1321_RS21395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BS1321_RS21405	COG1381	Involved in DNA repair and RecF pathway recombination
BS1321_RS21410	COG0752	glycyl-tRNA synthetase alpha subunit
BS1321_RS21415	COG0751	glycine-tRNA ligase activity
BS1321_RS21420	COG0517	IMP dehydrogenase activity
BS1321_RS21425	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BS1321_RS21430	COG1671	Belongs to the UPF0178 family
BS1321_RS21435	COG0358	DNA primase activity
BS1321_RS21440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BS1321_RS21450	COG2010	Cytochrome c
BS1321_RS21455	COG2384	SAM-dependent methyltransferase
BS1321_RS21460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BS1321_RS21475	COG0513	Belongs to the DEAD box helicase family
BS1321_RS21480	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BS1321_RS21490	COG1121	(ABC) transporter
BS1321_RS21495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BS1321_RS21500	COG0735	belongs to the Fur family
BS1321_RS21505	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
BS1321_RS21510	COG4709	membrane
BS1321_RS21535	COG5521	maltodextrose utilization protein MalA
BS1321_RS21540	COG2839	Protein conserved in bacteria
BS1321_RS21550	COG0477	Major facilitator Superfamily
BS1321_RS21555	COG0768	penicillin binding
BS1321_RS21560	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BS1321_RS21565	COG0573	inorganic phosphate transmembrane transporter activity
BS1321_RS21570	COG0581	inorganic phosphate transmembrane transporter activity
BS1321_RS21580	COG0704	Plays a role in the regulation of phosphate uptake
BS1321_RS21605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BS1321_RS21610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BS1321_RS21620	COG0457	Tetratricopeptide repeat
BS1321_RS21620	COG0705	Rhomboid family
BS1321_RS21635	COG1940	carbohydrate kinase activity
BS1321_RS21640	COG1368	sulfuric ester hydrolase activity
BS1321_RS21660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS21680	COG1393	Belongs to the ArsC family
BS1321_RS21685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BS1321_RS21690	COG1459	type II secretion system
BS1321_RS21695	COG4537	Required for transformation and DNA binding
BS1321_RS21730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BS1321_RS21740	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BS1321_RS21750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BS1321_RS21755	COG0095	Lipoate-protein ligase
BS1321_RS21760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BS1321_RS21775	COG1752	Esterase of the alpha-beta hydrolase superfamily
BS1321_RS21785	COG3872	metal-dependent enzyme
BS1321_RS21800	COG0006	proline dipeptidase activity
BS1321_RS21805	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BS1321_RS21810	COG3854	ATPases associated with a variety of cellular activities
BS1321_RS21850	COG0511	ligase activity, forming carbon-carbon bonds
BS1321_RS21855	COG0439	Biotin carboxylase
BS1321_RS21860	COG1302	Protein conserved in bacteria
BS1321_RS21865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BS1321_RS21870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BS1321_RS21875	COG1570	exodeoxyribonuclease VII activity
BS1321_RS21880	COG1722	exodeoxyribonuclease VII activity
BS1321_RS21885	COG0142	geranyltranstransferase activity
BS1321_RS21890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BS1321_RS21895	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BS1321_RS21900	COG1438	arginine binding
BS1321_RS21905	COG0497	DNA recombination
BS1321_RS21910	COG0750	zinc metalloprotease
BS1321_RS21915	COG0745	RESPONSE REGULATOR receiver
BS1321_RS21925	COG0584	glycerophosphoryl diester phosphodiesterase
BS1321_RS21935	COG3290	protein histidine kinase activity
BS1321_RS21935	COG3829	transcription factor binding
BS1321_RS21945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS1321_RS21950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS1321_RS21955	COG0022	dehydrogenase e1 component
BS1321_RS21960	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS1321_RS21965	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS1321_RS21970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS1321_RS21970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BS1321_RS21975	COG1703	isobutyryl-CoA mutase activity
BS1321_RS21985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS21990	COG0765	amino acid transport
BS1321_RS21995	COG1126	abc transporter atp-binding protein
BS1321_RS22000	COG4129	membrane
BS1321_RS22005	COG1376	ErfK ybiS ycfS ynhG family protein
BS1321_RS22010	COG0346	lactoylglutathione lyase activity
BS1321_RS22015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS1321_RS22020	COG2195	Cleaves the N-terminal amino acid of tripeptides
BS1321_RS22030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS1321_RS22035	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BS1321_RS22045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BS1321_RS22075	COG0789	Transcriptional regulator
BS1321_RS22085	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BS1321_RS22090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BS1321_RS22095	COG0300	oxidoreductase activity
BS1321_RS22105	COG1388	LysM domain
BS1321_RS22105	COG0791	NLP P60 protein
BS1321_RS22110	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BS1321_RS22120	COG4918	Iron-sulphur cluster biosynthesis
BS1321_RS22125	COG1073	alpha beta
BS1321_RS22135	COG1846	Transcriptional regulator
BS1321_RS22140	COG1764	response to oxidative stress
BS1321_RS22145	COG0667	Aldo Keto reductase
BS1321_RS22160	COG1379	DNA repair
BS1321_RS22170	COG1300	Membrane
BS1321_RS22175	COG0735	belongs to the Fur family
BS1321_RS22185	COG4974	Belongs to the 'phage' integrase family
BS1321_RS22205	COG1686	Belongs to the peptidase S11 family
BS1321_RS22215	COG2172	sigma factor antagonist activity
BS1321_RS22225	COG2252	PERMEase
BS1321_RS22245	COG0697	spore germination
BS1321_RS22255	COG4086	secreted protein
BS1321_RS22265	COG1547	Domain of unknown function (DUF309)
BS1321_RS22280	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BS1321_RS22295	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BS1321_RS22310	COG1686	Belongs to the peptidase S11 family
BS1321_RS22315	COG2715	membrane protein required for spore maturation
BS1321_RS22320	COG0700	Nucleoside recognition
BS1321_RS22325	COG1187	pseudouridine synthase activity
BS1321_RS22330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BS1321_RS22335	COG1333	cytochrome c biogenesis protein
BS1321_RS22340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BS1321_RS22345	COG0745	RESPONSE REGULATOR receiver
BS1321_RS22350	COG5002	protein histidine kinase activity
BS1321_RS22355	COG1595	DNA-templated transcription, initiation
BS1321_RS22365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BS1321_RS22370	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BS1321_RS22380	COG4955	Helix-turn-helix domain
BS1321_RS22385	COG0514	ATP-dependent DNA helicase (RecQ)
BS1321_RS22390	COG1266	CAAX protease self-immunity
BS1321_RS22395	COG1388	LysM domain
BS1321_RS22405	COG1408	metallophosphoesterase
BS1321_RS22415	COG4862	establishment of competence for transformation
BS1321_RS22420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS1321_RS22425	COG0492	ferredoxin-NADP+ reductase activity
BS1321_RS22435	COG2339	peptidase activity
BS1321_RS22440	COG3409	Peptidoglycan-binding domain 1 protein
BS1321_RS22440	COG3773	Cell wall hydrolase
BS1321_RS22445	COG2959	enzyme of heme biosynthesis
BS1321_RS22460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BS1321_RS22470	COG0539	negative regulation of cytoplasmic translation
BS1321_RS22495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BS1321_RS22500	COG0531	amino acid
BS1321_RS22510	COG3290	protein histidine kinase activity
BS1321_RS22510	COG3829	transcription factor binding
BS1321_RS22530	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS1321_RS22535	COG0776	regulation of translation
BS1321_RS22540	COG0302	gtp cyclohydrolase
BS1321_RS22550	COG0142	geranyltranstransferase activity
BS1321_RS22555	COG2226	methyltransferase
BS1321_RS22560	COG0142	geranyltranstransferase activity
BS1321_RS22565	COG0105	UTP biosynthetic process
BS1321_RS22570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BS1321_RS22575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BS1321_RS22580	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BS1321_RS22585	COG4401	Chorismate mutase type I
BS1321_RS22590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BS1321_RS22595	COG0287	Prephenate dehydrogenase
BS1321_RS22600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BS1321_RS22605	COG0457	Tetratricopeptide repeat
BS1321_RS22610	COG5582	Belongs to the UPF0302 family
BS1321_RS22630	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BS1321_RS22630	COG2010	Cytochrome c
BS1321_RS22635	COG4347	Protein of unknown function (DUF1405)
BS1321_RS22645	COG2738	Putative neutral zinc metallopeptidase
BS1321_RS22650	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS22655	COG1694	Mazg nucleotide pyrophosphohydrolase
BS1321_RS22665	COG1803	Methylglyoxal synthase
BS1321_RS22670	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BS1321_RS22675	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS22680	COG0617	tRNA 3'-terminal CCA addition
BS1321_RS22690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BS1321_RS22695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BS1321_RS22700	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BS1321_RS22705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BS1321_RS22705	COG1199	ATP-dependent helicase activity
BS1321_RS22720	COG0436	Aminotransferase
BS1321_RS22730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS1321_RS22735	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS22745	COG0196	riboflavin kinase activity
BS1321_RS22755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS22760	COG0583	DNA-binding transcription factor activity
BS1321_RS22780	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS1321_RS22795	COG0017	Asparaginyl-tRNA synthetase
BS1321_RS22800	COG3935	DnaD domain protein
BS1321_RS22805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BS1321_RS22815	COG4499	WXG100 protein secretion system (Wss), protein YukC
BS1321_RS22815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BS1321_RS22820	COG3331	DNA recombination
BS1321_RS22855	COG1111	helicase
BS1321_RS22855	COG1205	dead DEAH box helicase
BS1321_RS22860	COG3359	exonuclease
BS1321_RS22870	COG4474	Belongs to the UPF0398 family
BS1321_RS22875	COG3599	regulation of cell shape
BS1321_RS22885	COG0116	Belongs to the methyltransferase superfamily
BS1321_RS22890	COG1278	Cold shock
BS1321_RS22895	COG1199	ATP-dependent helicase activity
BS1321_RS22900	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BS1321_RS22905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BS1321_RS22910	COG2233	PERMEase
BS1321_RS22920	COG3424	synthase
BS1321_RS22925	COG1755	Isoprenylcysteine carboxyl methyltransferase
BS1321_RS22930	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BS1321_RS22945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BS1321_RS22960	COG0328	RNA-DNA hybrid ribonuclease activity
BS1321_RS22965	COG0328	RNA-DNA hybrid ribonuclease activity
BS1321_RS22975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BS1321_RS22980	COG1959	2 iron, 2 sulfur cluster binding
BS1321_RS22995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BS1321_RS23000	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BS1321_RS23015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BS1321_RS23025	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS23030	COG0028	Belongs to the TPP enzyme family
BS1321_RS23035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS1321_RS23040	COG0833	amino acid
BS1321_RS23050	COG4638	Rieske (2fe-2S)
BS1321_RS23095	COG0697	spore germination
BS1321_RS23135	COG0531	amino acid
BS1321_RS23140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BS1321_RS23160	COG2235	arginine
BS1321_RS23165	COG4187	Peptidase family M20/M25/M40
BS1321_RS23170	COG1288	antiporter activity
BS1321_RS23180	COG1834	amidinotransferase
BS1321_RS23185	COG0833	amino acid
BS1321_RS23220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BS1321_RS23225	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS23235	COG1454	alcohol dehydrogenase
BS1321_RS23245	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS23255	COG1649	PFAM Uncharacterised BCR, COG1649
BS1321_RS23270	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BS1321_RS23280	COG1486	melibiose metabolic process
BS1321_RS23285	COG1447	Phosphotransferase system cellobiose-specific component IIA
BS1321_RS23295	COG2971	BadF BadG BcrA BcrD
BS1321_RS23300	COG1737	Transcriptional regulator
BS1321_RS23305	COG2188	Transcriptional regulator
BS1321_RS23310	COG2814	Major facilitator Superfamily
BS1321_RS23315	COG1309	transcriptional regulator
BS1321_RS23325	COG0702	epimerase
BS1321_RS23355	COG2188	Transcriptional regulator
BS1321_RS23360	COG1609	Transcriptional regulator
BS1321_RS23375	COG1175	transmembrane transport
BS1321_RS23380	COG0395	ABC-type sugar transport system, permease component
BS1321_RS23385	COG1940	carbohydrate kinase activity
BS1321_RS23390	COG2222	sugar isomerase
BS1321_RS23400	COG3684	Belongs to the aldolase LacD family
BS1321_RS23405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BS1321_RS23410	COG3715	PTS system
BS1321_RS23415	COG3716	PTS system mannose fructose sorbose family IID component
BS1321_RS23445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BS1321_RS23470	COG1027	Aspartate ammonia-lyase
BS1321_RS23480	COG1802	Transcriptional regulator
BS1321_RS23485	COG2234	aminopeptidase activity
BS1321_RS23490	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS1321_RS23495	COG4208	sulfate ABC transporter
BS1321_RS23500	COG4143	(ABC) transporter
BS1321_RS23505	COG3842	ATPase activity
BS1321_RS23515	COG0789	Transcriptional regulator
BS1321_RS23520	COG2814	Major facilitator Superfamily
BS1321_RS23525	COG1064	alcohol dehydrogenase
BS1321_RS23540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BS1321_RS23545	COG0789	Transcriptional regulator
BS1321_RS23550	COG4326	sporulation control protein
BS1321_RS23555	COG1388	LysM domain
BS1321_RS23555	COG0791	NLP P60 protein
BS1321_RS23565	COG0251	oxidation-reduction process
BS1321_RS23570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BS1321_RS23575	COG4974	Belongs to the 'phage' integrase family
BS1321_RS23630	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BS1321_RS23675	COG0785	Cytochrome C biogenesis protein
BS1321_RS23700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS23705	COG0805	protein transport
BS1321_RS23750	COG1247	-acetyltransferase
BS1321_RS23780	COG2132	Multicopper oxidase
BS1321_RS23795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BS1321_RS23800	COG1321	iron dependent repressor
BS1321_RS23805	COG2226	methyltransferase
BS1321_RS23815	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BS1321_RS23825	COG0386	Belongs to the glutathione peroxidase family
BS1321_RS23830	COG1307	EDD domain protein, DegV family
BS1321_RS23835	COG1418	mRNA catabolic process
BS1321_RS23840	COG0488	(ABC) transporter
BS1321_RS23845	COG1413	lyase activity
BS1321_RS23850	COG0129	dihydroxy-acid dehydratase activity
BS1321_RS23860	COG2521	methyltransferase
BS1321_RS23860	COG2136	Putative SAM-dependent methyltransferase
BS1321_RS23865	COG0405	Gamma-glutamyltransferase
BS1321_RS23875	COG0861	Integral membrane protein TerC family
BS1321_RS23880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS1321_RS23900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BS1321_RS23905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BS1321_RS23910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS23915	COG0805	protein transport
BS1321_RS23925	COG1307	EDD domain protein, DegV family
BS1321_RS23930	COG1999	signal sequence binding
BS1321_RS23935	COG2755	lipolytic protein G-D-S-L family
BS1321_RS23950	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS1321_RS23955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BS1321_RS23970	COG1619	proteins homologs of microcin C7 resistance protein MccF
BS1321_RS24090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS1321_RS24095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BS1321_RS24100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BS1321_RS24105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BS1321_RS24110	COG0456	acetyltransferase
BS1321_RS24115	COG3829	transcription factor binding
BS1321_RS24120	COG1509	lysine 2,3-aminomutase activity
BS1321_RS24135	COG4191	Histidine kinase
BS1321_RS24150	COG0813	purine-nucleoside phosphorylase activity
BS1321_RS24155	COG3409	Peptidoglycan-binding domain 1 protein
BS1321_RS24155	COG0793	Belongs to the peptidase S41A family
BS1321_RS24165	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BS1321_RS24170	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BS1321_RS24175	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BS1321_RS24180	COG0436	Aminotransferase
BS1321_RS24185	COG1850	ribulose-bisphosphate carboxylase activity
BS1321_RS24190	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
BS1321_RS24195	COG0235	Class ii aldolase
BS1321_RS24200	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BS1321_RS24205	COG0523	cobalamin synthesis protein
BS1321_RS24210	COG4876	unkown
BS1321_RS24230	COG0745	RESPONSE REGULATOR receiver
BS1321_RS24235	COG5002	protein histidine kinase activity
BS1321_RS24245	COG2340	Cysteine-rich secretory protein family
BS1321_RS24255	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS24260	COG0534	Mate efflux family protein
BS1321_RS24265	COG0668	transmembrane transport
BS1321_RS24280	COG1346	cytolysis
BS1321_RS24285	COG1380	Effector of murein hydrolase LrgA
BS1321_RS24310	COG0288	reversible hydration of carbon dioxide
BS1321_RS24320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BS1321_RS24325	COG3285	dna ligase
BS1321_RS24325	COG1793	dna ligase
BS1321_RS24330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BS1321_RS24335	COG2258	MOSC domain
BS1321_RS24340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BS1321_RS24340	COG0646	methionine synthase
BS1321_RS24345	COG1410	methionine synthase
BS1321_RS24345	COG0646	methionine synthase
BS1321_RS24350	COG0726	polysaccharide deacetylase
BS1321_RS24355	COG3384	dioxygenase
BS1321_RS24360	COG0567	Dehydrogenase, E1 component
BS1321_RS24365	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS1321_RS24370	COG1349	DNA-binding transcription factor activity
BS1321_RS24375	COG1105	Belongs to the carbohydrate kinase PfkB family
BS1321_RS24380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BS1321_RS24380	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS1321_RS24380	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BS1321_RS24400	COG0432	Pfam Uncharacterised protein family UPF0047
BS1321_RS24410	COG3773	Cell wall hydrolase
BS1321_RS24415	COG0640	Transcriptional regulator
BS1321_RS24420	COG1272	protein, Hemolysin III
BS1321_RS24430	COG1268	BioY protein
BS1321_RS24435	COG1585	Membrane protein implicated in regulation of membrane protease activity
BS1321_RS24440	COG2268	Band 7 protein
BS1321_RS24465	COG0778	Nitroreductase
BS1321_RS24470	COG1846	Transcriptional regulator
BS1321_RS24475	COG0656	L-ascorbic acid biosynthetic process
BS1321_RS24485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS24505	COG0531	amino acid
BS1321_RS24515	COG0697	spore germination
BS1321_RS24530	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS24540	COG0697	spore germination
BS1321_RS24545	COG0697	spore germination
BS1321_RS24555	COG0488	(ABC) transporter
BS1321_RS24560	COG1714	RDD family
BS1321_RS24570	COG3973	AAA domain
BS1321_RS24600	COG2996	Protein conserved in bacteria
BS1321_RS24605	COG3546	catalase activity
BS1321_RS24620	COG1388	LysM domain
BS1321_RS24620	COG3584	3D domain protein
BS1321_RS24625	COG0514	ATP-dependent DNA helicase (RecQ)
BS1321_RS24640	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BS1321_RS24645	COG5002	protein histidine kinase activity
BS1321_RS24650	COG2814	Major facilitator Superfamily
BS1321_RS24660	COG1131	(ABC) transporter
BS1321_RS24665	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BS1321_RS24675	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BS1321_RS24680	COG1506	peptidase
BS1321_RS24680	COG0823	Involved in the tonB-independent uptake of proteins
BS1321_RS24680	COG4946	Tricorn protease homolog
BS1321_RS24695	COG1733	regulation of RNA biosynthetic process
BS1321_RS24700	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
BS1321_RS24730	COG1764	response to oxidative stress
BS1321_RS24735	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS24755	COG0346	lactoylglutathione lyase activity
BS1321_RS24760	COG0346	lactoylglutathione lyase activity
BS1321_RS24765	COG0400	carboxylic ester hydrolase activity
BS1321_RS24770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BS1321_RS24775	COG0833	amino acid
BS1321_RS24780	COG2040	homocysteine
BS1321_RS24785	COG1396	sequence-specific DNA binding
BS1321_RS24790	COG0252	asparaginase activity
BS1321_RS24795	COG1027	Aspartate ammonia-lyase
BS1321_RS24810	COG1937	Protein conserved in bacteria
BS1321_RS24815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS1321_RS24820	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS24825	COG1388	LysM domain
BS1321_RS24825	COG3858	chitin binding
BS1321_RS24840	COG1132	(ABC) transporter
BS1321_RS24845	COG1482	cell wall glycoprotein biosynthetic process
BS1321_RS24850	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BS1321_RS24855	COG1088	dTDP-glucose 4,6-dehydratase activity
BS1321_RS24860	COG1091	dTDP-4-dehydrorhamnose reductase activity
BS1321_RS24865	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BS1321_RS24880	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BS1321_RS24880	COG0662	Cupin 2, conserved barrel domain protein
BS1321_RS24950	COG0463	Glycosyl transferase, family 2
BS1321_RS24965	COG1216	Glycosyl transferase, family 2
BS1321_RS24965	COG0463	Glycosyl transferase, family 2
BS1321_RS25005	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS1321_RS25015	COG1917	Cupin 2, conserved barrel domain protein
BS1321_RS25015	COG2207	Transcriptional regulator
BS1321_RS25020	COG2271	Major facilitator Superfamily
BS1321_RS25025	COG1473	amidohydrolase
BS1321_RS25030	COG1760	l-serine dehydratase
BS1321_RS25045	COG5002	protein histidine kinase activity
BS1321_RS25050	COG0745	RESPONSE REGULATOR receiver
BS1321_RS25055	COG0666	response to abiotic stimulus
BS1321_RS25065	COG0840	transmembrane signaling receptor activity
BS1321_RS25070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BS1321_RS25075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BS1321_RS25080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BS1321_RS25085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BS1321_RS25095	COG0129	dihydroxy-acid dehydratase activity
BS1321_RS25100	COG1414	Transcriptional regulator
BS1321_RS25110	COG2721	sulfolactate sulfo-lyase activity
BS1321_RS25115	COG2721	sulfolactate sulfo-lyase activity
BS1321_RS25120	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS25125	COG4948	Mandelate Racemase Muconate Lactonizing
BS1321_RS25130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BS1321_RS25145	COG0179	Fumarylacetoacetate (FAA) hydrolase
BS1321_RS25150	COG1606	tRNA processing
BS1321_RS25155	COG1691	(AIR) carboxylase
BS1321_RS25160	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BS1321_RS25165	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BS1321_RS25185	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BS1321_RS25190	COG1063	alcohol dehydrogenase
BS1321_RS25195	COG0800	Aldolase
BS1321_RS25200	COG1312	Catalyzes the dehydration of D-mannonate
BS1321_RS25205	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS25210	COG1609	Transcriptional regulator
BS1321_RS25215	COG2271	Major facilitator Superfamily
BS1321_RS25220	COG2207	Transcriptional regulator
BS1321_RS25220	COG3708	Transcriptional regulator
BS1321_RS25225	COG2721	sulfolactate sulfo-lyase activity
BS1321_RS25230	COG1063	alcohol dehydrogenase
BS1321_RS25235	COG0246	Mannitol dehydrogenase
BS1321_RS25240	COG0861	Integral membrane protein TerC family
BS1321_RS25245	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS25255	COG3852	Histidine kinase
BS1321_RS25260	COG1113	amino acid transport
BS1321_RS25275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BS1321_RS25280	COG0561	phosphatase activity
BS1321_RS25290	COG1511	domain protein
BS1321_RS25295	COG2176	DNA-directed DNA polymerase activity
BS1321_RS25310	COG2340	Cysteine-rich secretory protein family
BS1321_RS25335	COG4166	transmembrane transport
BS1321_RS25340	COG0601	transmembrane transport
BS1321_RS25345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BS1321_RS25350	COG0444	Belongs to the ABC transporter superfamily
BS1321_RS25355	COG4608	Belongs to the ABC transporter superfamily
BS1321_RS25360	COG1024	Enoyl-CoA hydratase
BS1321_RS25365	COG1278	Cold shock
BS1321_RS25375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BS1321_RS25380	COG1012	belongs to the aldehyde dehydrogenase family
BS1321_RS25385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BS1321_RS25400	COG2706	6-phosphogluconolactonase activity
BS1321_RS25410	COG0590	tRNA wobble adenosine to inosine editing
BS1321_RS25415	COG0679	Auxin Efflux Carrier
BS1321_RS25425	COG1126	abc transporter atp-binding protein
BS1321_RS25430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BS1321_RS25435	COG0765	amino acid transport
BS1321_RS25440	COG0765	amino acid transport
BS1321_RS25465	COG1376	ErfK ybiS ycfS ynhG family protein
BS1321_RS25475	COG0628	permease
BS1321_RS25480	COG2223	nitrite transmembrane transporter activity
BS1321_RS25485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BS1321_RS25495	COG2197	response regulator
BS1321_RS25515	COG3403	YqcI/YcgG family
BS1321_RS25525	COG1164	Oligoendopeptidase f
BS1321_RS25535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS25540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BS1321_RS25550	COG3048	D-serine ammonia-lyase activity
BS1321_RS25555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BS1321_RS25560	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BS1321_RS25565	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BS1321_RS25580	COG0431	NADPH-dependent FMN reductase
BS1321_RS25590	COG0175	sulfate reduction
BS1321_RS25595	COG2046	Belongs to the sulfate adenylyltransferase family
BS1321_RS25600	COG0529	Catalyzes the synthesis of activated sulfate
BS1321_RS25605	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS1321_RS25630	COG0730	response to heat
BS1321_RS25635	COG3663	DNA glycosylase
BS1321_RS25655	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BS1321_RS25660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS1321_RS25665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BS1321_RS25670	COG0297	glycogen (starch) synthase activity
BS1321_RS25675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BS1321_RS25680	COG0708	Exodeoxyribonuclease III
BS1321_RS25705	COG0406	alpha-ribazole phosphatase activity
BS1321_RS25710	COG0702	epimerase
BS1321_RS25720	COG0501	Belongs to the peptidase M48B family
BS1321_RS25725	COG2259	Doxx family
BS1321_RS25755	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS25785	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BS1321_RS25790	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BS1321_RS25820	COG0438	transferase activity, transferring glycosyl groups
BS1321_RS25825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BS1321_RS25845	COG2814	Major facilitator Superfamily
BS1321_RS25860	COG0716	FMN binding
BS1321_RS25870	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS25875	COG1125	glycine betaine transport
BS1321_RS25875	COG0517	IMP dehydrogenase activity
BS1321_RS25880	COG1174	glycine betaine transport
BS1321_RS25885	COG1732	Glycine betaine
BS1321_RS25890	COG1174	glycine betaine transport
BS1321_RS25895	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BS1321_RS25905	COG0583	DNA-binding transcription factor activity
BS1321_RS25925	COG1388	LysM domain
BS1321_RS25925	COG0791	NLP P60 protein
BS1321_RS25930	COG0542	response to heat
BS1321_RS25935	COG1523	belongs to the glycosyl hydrolase 13 family
BS1321_RS25945	COG3383	formate dehydrogenase (NAD+) activity
BS1321_RS25955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS1321_RS25955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BS1321_RS25960	COG2427	Protein of unknown function (DUF1641)
BS1321_RS25965	COG0697	spore germination
BS1321_RS25975	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
BS1321_RS25985	COG4294	response to UV
BS1321_RS26000	COG0582	viral genome integration into host DNA
BS1321_RS26015	COG1802	Transcriptional regulator
BS1321_RS26020	COG0579	oxidoreductase
BS1321_RS26050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BS1321_RS26065	COG2814	Major facilitator Superfamily
BS1321_RS26070	COG0069	glutamate synthase activity
BS1321_RS26075	COG2508	Transcriptional regulator
BS1321_RS26080	COG3835	regulator
BS1321_RS26090	COG1929	Belongs to the glycerate kinase type-1 family
BS1321_RS26095	COG2610	gluconate transmembrane transporter activity
BS1321_RS26125	COG0668	transmembrane transport
BS1321_RS26135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BS1321_RS26145	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BS1321_RS26150	COG1609	Transcriptional regulator
BS1321_RS26160	COG1175	transmembrane transport
BS1321_RS26165	COG0395	ABC-type sugar transport system, permease component
BS1321_RS26170	COG3345	alpha-galactosidase
BS1321_RS26175	COG1069	ribulokinase activity
BS1321_RS26195	COG2223	nitrite transmembrane transporter activity
BS1321_RS26200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS1321_RS26205	COG0243	molybdopterin cofactor binding
BS1321_RS26220	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BS1321_RS26225	COG2146	nitrite reductase [NAD(P)H] activity
BS1321_RS26260	COG0640	Transcriptional regulator
BS1321_RS26265	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
BS1321_RS26275	COG5002	protein histidine kinase activity
BS1321_RS26280	COG2204	response regulator
BS1321_RS26290	COG1840	ABC-type Fe3 transport system, periplasmic component
BS1321_RS26295	COG3842	ATPase activity
BS1321_RS26300	COG1176	ABC-type spermidine putrescine transport system, permease component I
BS1321_RS26315	COG0277	FAD linked oxidase domain protein
BS1321_RS26320	COG0247	lactate metabolic process
BS1321_RS26325	COG1280	lysine exporter protein (LysE YggA)
BS1321_RS26330	COG1378	Sugar-specific transcriptional regulator TrmB
BS1321_RS26340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BS1321_RS26345	COG1802	Transcriptional regulator
BS1321_RS26350	COG0697	spore germination
BS1321_RS26355	COG4221	oxidoreductase activity
BS1321_RS26365	COG0789	Transcriptional regulator
BS1321_RS26370	COG5002	protein histidine kinase activity
BS1321_RS26385	COG2318	DinB family
BS1321_RS26420	COG3284	Transcriptional regulator
BS1321_RS26425	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS26430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BS1321_RS26435	COG0508	dehydrogenase complex catalyzes the overall conversion of
BS1321_RS26440	COG0022	dehydrogenase e1 component
BS1321_RS26445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BS1321_RS26455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BS1321_RS26460	COG2205	protein histidine kinase activity
BS1321_RS26465	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS26480	COG0024	Methionine aminopeptidase
BS1321_RS26500	COG2318	DinB family
BS1321_RS26520	COG0741	lytic transglycosylase activity
BS1321_RS26535	COG1028	Short-chain dehydrogenase reductase Sdr
BS1321_RS26545	COG1802	Transcriptional regulator
BS1321_RS26555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BS1321_RS26555	COG0515	serine threonine protein kinase
BS1321_RS26570	COG3706	GGDEF domain
BS1321_RS26580	COG2205	protein histidine kinase activity
BS1321_RS26590	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BS1321_RS26595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BS1321_RS26600	COG5609	conserved protein (DUF2294)
BS1321_RS26615	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BS1321_RS26655	COG0833	amino acid
BS1321_RS26665	COG2244	polysaccharide biosynthetic process
BS1321_RS26710	COG3706	GGDEF domain
BS1321_RS26730	COG0697	spore germination
BS1321_RS26735	COG1742	UPF0060 membrane protein
BS1321_RS26740	COG2814	Major facilitator Superfamily
BS1321_RS26750	COG2814	Major facilitator Superfamily
BS1321_RS26760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BS1321_RS26765	COG0840	transmembrane signaling receptor activity
BS1321_RS26770	COG0531	amino acid
BS1321_RS26810	COG1876	peptidase activity
BS1321_RS26825	COG0596	Alpha beta hydrolase
BS1321_RS26830	COG2208	phosphoserine phosphatase activity
BS1321_RS26845	COG1942	4-Oxalocrotonate Tautomerase
BS1321_RS26850	COG4977	sequence-specific DNA binding
BS1321_RS26850	COG1917	Cupin 2, conserved barrel domain protein
BS1321_RS26855	COG2814	Major facilitator Superfamily
BS1321_RS26860	COG0673	inositol 2-dehydrogenase activity
BS1321_RS26865	COG1082	Xylose isomerase domain protein TIM barrel
BS1321_RS26875	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BS1321_RS26920	COG5444	nuclease activity
BS1321_RS26955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BS1321_RS26960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BS1321_RS26965	COG1335	isochorismatase
BS1321_RS26970	COG0494	nUDIX hydrolase
BS1321_RS26975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BS1321_RS26980	COG1024	Enoyl-CoA hydratase
BS1321_RS26985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BS1321_RS26990	COG0511	ligase activity, forming carbon-carbon bonds
BS1321_RS26995	COG0439	Biotin carboxylase
BS1321_RS27000	COG0318	PFAM AMP-dependent synthetase and ligase
BS1321_RS27005	COG1960	acyl-CoA dehydrogenase activity
BS1321_RS27010	COG1309	transcriptional regulator
BS1321_RS27020	COG1294	oxidase, subunit
BS1321_RS27025	COG1271	oxidase subunit
BS1321_RS27040	COG1607	acyl-coa hydrolase
BS1321_RS27050	COG0506	proline dehydrogenase activity
BS1321_RS27055	COG1231	oxidoreductase activity
BS1321_RS27065	COG0814	amino acid
BS1321_RS27070	COG0697	spore germination
BS1321_RS27095	COG0805	protein transport
BS1321_RS27105	COG1876	peptidase activity
BS1321_RS27110	COG1316	TRANSCRIPTIONal
BS1321_RS27130	COG0745	RESPONSE REGULATOR receiver
BS1321_RS27145	COG1086	Polysaccharide biosynthesis protein
BS1321_RS27150	COG1295	ribonuclease BN