locus-tag	class	description
B1NLA3E_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
B1NLA3E_RS00010	COG0592	DNA-directed DNA polymerase activity
B1NLA3E_RS00015	COG2501	S4 domain
B1NLA3E_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B1NLA3E_RS00030	COG0187	DNA topoisomerase II activity
B1NLA3E_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1NLA3E_RS00070	COG0516	GMP reductase activity
B1NLA3E_RS00070	COG0517	IMP dehydrogenase activity
B1NLA3E_RS00085	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
B1NLA3E_RS00090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
B1NLA3E_RS00100	COG1428	Deoxynucleoside kinase
B1NLA3E_RS00105	COG1428	Deoxynucleoside kinase
B1NLA3E_RS00110	COG3858	chitin binding
B1NLA3E_RS00110	COG1388	LysM domain
B1NLA3E_RS00115	COG2200	EAL domain
B1NLA3E_RS00115	COG2199	diguanylate cyclase activity
B1NLA3E_RS00120	COG0590	tRNA wobble adenosine to inosine editing
B1NLA3E_RS00125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B1NLA3E_RS00130	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
B1NLA3E_RS00135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B1NLA3E_RS00180	COG1982	Orn Lys Arg decarboxylase major
B1NLA3E_RS00185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
B1NLA3E_RS00190	COG3870	Protein conserved in bacteria
B1NLA3E_RS00195	COG0470	DNA polymerase III
B1NLA3E_RS00200	COG1774	PSP1 C-terminal conserved region
B1NLA3E_RS00205	COG4467	Involved in initiation control of chromosome replication
B1NLA3E_RS00210	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B1NLA3E_RS00220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
B1NLA3E_RS00225	COG2002	toxin-antitoxin pair type II binding
B1NLA3E_RS00235	COG0084	hydrolase, TatD family'
B1NLA3E_RS00240	COG3583	domain protein
B1NLA3E_RS00240	COG3584	3D domain protein
B1NLA3E_RS00250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B1NLA3E_RS00260	COG4466	Protein conserved in bacteria
B1NLA3E_RS00270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
B1NLA3E_RS00275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_RS00280	COG0251	oxidation-reduction process
B1NLA3E_RS00285	COG2088	sporulation resulting in formation of a cellular spore
B1NLA3E_RS00290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1NLA3E_RS00300	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1NLA3E_RS00305	COG0193	aminoacyl-tRNA hydrolase activity
B1NLA3E_RS00315	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B1NLA3E_RS00320	COG2002	toxin-antitoxin pair type II binding
B1NLA3E_RS00325	COG2244	polysaccharide biosynthetic process
B1NLA3E_RS00330	COG3956	TIGRFAM MazG family protein
B1NLA3E_RS00335	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B1NLA3E_RS00355	COG1098	S1 RNA binding domain
B1NLA3E_RS00365	COG2208	phosphoserine phosphatase activity
B1NLA3E_RS00370	COG2304	oxidoreductase activity
B1NLA3E_RS00375	COG0515	serine threonine protein kinase
B1NLA3E_RS00385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1NLA3E_RS00390	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
B1NLA3E_RS00395	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B1NLA3E_RS00400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_RS00405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_RS00410	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B1NLA3E_RS00415	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B1NLA3E_RS00420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B1NLA3E_RS00425	COG1396	sequence-specific DNA binding
B1NLA3E_RS00430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1NLA3E_RS00520	COG3880	PFAM UvrB UvrC protein
B1NLA3E_RS00525	COG3869	Catalyzes the specific phosphorylation of arginine residues in
B1NLA3E_RS00530	COG0542	response to heat
B1NLA3E_RS00535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
B1NLA3E_RS00540	COG4956	integral membrane protein (PIN domain superfamily)
B1NLA3E_RS00545	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
B1NLA3E_RS00550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
B1NLA3E_RS00555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B1NLA3E_RS00560	COG1045	serine acetyltransferase
B1NLA3E_RS00565	COG0215	cysteine-tRNA ligase activity
B1NLA3E_RS00575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1NLA3E_RS00580	COG3688	RNA-binding protein containing a PIN domain
B1NLA3E_RS00590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1NLA3E_RS00595	COG0250	Participates in transcription elongation, termination and antitermination
B1NLA3E_RS00600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
B1NLA3E_RS00605	COG0081	regulation of translation
B1NLA3E_RS00615	COG0222	ribosome binding
B1NLA3E_RS00620	COG2813	Specifically methylates the guanine in position
B1NLA3E_RS00625	COG0085	RNA polymerase activity
B1NLA3E_RS00630	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
B1NLA3E_RS00635	COG1358	cellular component organization or biogenesis
B1NLA3E_RS00640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
B1NLA3E_RS00645	COG0049	tRNA binding
B1NLA3E_RS00650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
B1NLA3E_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
B1NLA3E_RS00660	COG0051	transcription antitermination factor activity, RNA binding
B1NLA3E_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
B1NLA3E_RS00670	COG0088	Forms part of the polypeptide exit tunnel
B1NLA3E_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
B1NLA3E_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
B1NLA3E_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
B1NLA3E_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
B1NLA3E_RS00715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
B1NLA3E_RS00720	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
B1NLA3E_RS00740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
B1NLA3E_RS00745	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
B1NLA3E_RS00750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
B1NLA3E_RS00755	COG1841	ribosomal large subunit assembly
B1NLA3E_RS00760	COG0200	Binds to the 23S rRNA
B1NLA3E_RS00765	COG0201	protein transport
B1NLA3E_RS00770	COG0563	adenylate kinase activity
B1NLA3E_RS00775	COG0024	Methionine aminopeptidase
B1NLA3E_RS00780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
B1NLA3E_RS00785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
B1NLA3E_RS00790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B1NLA3E_RS00795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
B1NLA3E_RS00800	COG0202	RNA polymerase activity
B1NLA3E_RS00805	COG0203	ribosomal protein L17
B1NLA3E_RS00810	COG1122	ATPase activity
B1NLA3E_RS00815	COG1122	ATPase activity
B1NLA3E_RS00820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B1NLA3E_RS00830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B1NLA3E_RS00835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B1NLA3E_RS00865	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_RS00870	COG0489	protein tyrosine kinase activity
B1NLA3E_RS00880	COG2194	sulfuric ester hydrolase activity
B1NLA3E_RS00885	COG0726	polysaccharide deacetylase
B1NLA3E_RS00955	COG1595	DNA-templated transcription, initiation
B1NLA3E_RS00960	COG5662	AntiSigma factor
B1NLA3E_RS00965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B1NLA3E_RS00970	COG4856	YbbR-like protein
B1NLA3E_RS00975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1NLA3E_RS00980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B1NLA3E_RS00985	COG0778	Nitroreductase
B1NLA3E_RS00995	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_RS01010	COG3711	transcriptional antiterminator
B1NLA3E_RS01030	COG2323	membrane
B1NLA3E_RS01035	COG3300	MHYT domain
B1NLA3E_RS01035	COG5001	Diguanylate cyclase
B1NLA3E_RS01045	COG1253	flavin adenine dinucleotide binding
B1NLA3E_RS01050	COG2239	Acts as a magnesium transporter
B1NLA3E_RS01060	COG1181	Belongs to the D-alanine--D-alanine ligase family
B1NLA3E_RS01065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B1NLA3E_RS01070	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1NLA3E_RS01075	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_RS01080	COG4294	response to UV
B1NLA3E_RS01085	COG3402	PFAM membrane-flanked domain
B1NLA3E_RS01090	COG3428	Bacterial PH domain
B1NLA3E_RS01095	COG0705	Rhomboid family
B1NLA3E_RS01100	COG0736	holo-[acyl-carrier-protein] synthase activity
B1NLA3E_RS01105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B1NLA3E_RS01115	COG0864	Transcriptional regulator
B1NLA3E_RS01120	COG2337	Toxic component of a toxin-antitoxin (TA) module
B1NLA3E_RS01125	COG2183	response to ionizing radiation
B1NLA3E_RS01130	COG3091	SprT-like family
B1NLA3E_RS01210	COG0802	atpase or kinase
B1NLA3E_RS01215	COG1214	PFAM Peptidase M22, glycoprotease
B1NLA3E_RS01220	COG0456	acetyltransferase
B1NLA3E_RS01230	COG0488	(ABC) transporter
B1NLA3E_RS01235	COG0315	cyclic pyranopterin monophosphate synthase activity
B1NLA3E_RS01240	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
B1NLA3E_RS01245	COG2508	Transcriptional regulator
B1NLA3E_RS01250	COG1053	succinate dehydrogenase
B1NLA3E_RS01260	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_RS01265	COG0805	protein transport
B1NLA3E_RS01275	COG1266	CAAX protease self-immunity
B1NLA3E_RS01280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
B1NLA3E_RS01285	COG0459	protein refolding
B1NLA3E_RS01290	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_RS01295	COG2856	Zn peptidase
B1NLA3E_RS01320	COG1395	domain, Protein
B1NLA3E_RS01325	COG1476	TRANSCRIPTIONal
B1NLA3E_RS01405	COG2201	protein-glutamate methylesterase activity
B1NLA3E_RS01425	COG1595	DNA-templated transcription, initiation
B1NLA3E_RS01445	COG5484	DNA packaging
B1NLA3E_RS01450	COG1783	phage Terminase large subunit
B1NLA3E_RS01455	COG5518	Phage portal protein
B1NLA3E_RS01460	COG2369	cell adhesion
B1NLA3E_RS01470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
B1NLA3E_RS01475	COG4653	Phage capsid family
B1NLA3E_RS01655	COG3959	Transketolase, thiamine diphosphate binding domain
B1NLA3E_RS01660	COG3958	Transketolase
B1NLA3E_RS01665	COG1063	alcohol dehydrogenase
B1NLA3E_RS01675	COG2186	Transcriptional regulator
B1NLA3E_RS01680	COG0205	6-phosphofructokinase activity
B1NLA3E_RS01695	COG0277	FAD linked oxidase domain protein
B1NLA3E_RS01700	COG2086	electron transfer activity
B1NLA3E_RS01705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS01715	COG2086	electron transfer activity
B1NLA3E_RS01720	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS01725	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
B1NLA3E_RS01730	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS01735	COG2223	nitrite transmembrane transporter activity
B1NLA3E_RS01740	COG1070	Carbohydrate kinase
B1NLA3E_RS01745	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B1NLA3E_RS01750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B1NLA3E_RS01760	COG0039	L-malate dehydrogenase activity
B1NLA3E_RS01765	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS01770	COG2350	Protein conserved in bacteria
B1NLA3E_RS01775	COG0714	Associated with various cellular activities
B1NLA3E_RS01780	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
B1NLA3E_RS01785	COG1305	Transglutaminase-like
B1NLA3E_RS01790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B1NLA3E_RS01790	COG0519	Catalyzes the synthesis of GMP from XMP
B1NLA3E_RS01795	COG2252	PERMEase
B1NLA3E_RS01800	COG3711	transcriptional antiterminator
B1NLA3E_RS01805	COG2190	(PTS) system
B1NLA3E_RS01805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B1NLA3E_RS01805	COG1263	PTS System
B1NLA3E_RS01845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B1NLA3E_RS01850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B1NLA3E_RS01855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B1NLA3E_RS01860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
B1NLA3E_RS01865	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B1NLA3E_RS01880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
B1NLA3E_RS01885	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
B1NLA3E_RS01890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B1NLA3E_RS01900	COG0151	Belongs to the GarS family
B1NLA3E_RS01915	COG1470	cell adhesion involved in biofilm formation
B1NLA3E_RS01920	COG4496	protein, YerC YecD
B1NLA3E_RS01925	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
B1NLA3E_RS01930	COG0210	DNA helicase
B1NLA3E_RS01935	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B1NLA3E_RS01940	COG4851	CamS sex pheromone cAM373 precursor
B1NLA3E_RS01945	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS01950	COG2224	Isocitrate lyase
B1NLA3E_RS01960	COG5506	Protein of unknown function (DUF1694)
B1NLA3E_RS01965	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1NLA3E_RS01970	COG0154	amidase activity
B1NLA3E_RS01975	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B1NLA3E_RS01980	COG2205	protein histidine kinase activity
B1NLA3E_RS01985	COG1597	lipid kinase activity
B1NLA3E_RS01990	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B1NLA3E_RS02000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1NLA3E_RS02005	COG0166	Belongs to the GPI family
B1NLA3E_RS02010	COG1733	regulation of RNA biosynthetic process
B1NLA3E_RS02020	COG0730	response to heat
B1NLA3E_RS02030	COG1309	transcriptional regulator
B1NLA3E_RS02035	COG1272	protein, Hemolysin III
B1NLA3E_RS02050	COG2897	thiosulfate sulfurtransferase activity
B1NLA3E_RS02060	COG1607	acyl-coa hydrolase
B1NLA3E_RS02065	COG1607	acyl-coa hydrolase
B1NLA3E_RS02070	COG0789	Transcriptional regulator
B1NLA3E_RS02075	COG1664	Polymer-forming cytoskeletal
B1NLA3E_RS02085	COG2409	Drug exporters of the RND superfamily
B1NLA3E_RS02090	COG3279	Response regulator of the LytR AlgR family
B1NLA3E_RS02095	COG0427	acetyl-CoA hydrolase
B1NLA3E_RS02150	COG0596	Alpha beta hydrolase
B1NLA3E_RS02165	COG0697	spore germination
B1NLA3E_RS02170	COG2116	formate transmembrane transporter activity
B1NLA3E_RS02185	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_RS02215	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
B1NLA3E_RS02245	COG1492	cobalamin metabolic process
B1NLA3E_RS02260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
B1NLA3E_RS02265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1NLA3E_RS02275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
B1NLA3E_RS02325	COG1404	Belongs to the peptidase S8 family
B1NLA3E_RS02330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_RS02335	COG0789	Transcriptional regulator
B1NLA3E_RS02345	COG0765	amino acid transport
B1NLA3E_RS02360	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1NLA3E_RS02365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_RS02370	COG2966	Psort location CytoplasmicMembrane, score
B1NLA3E_RS02375	COG3610	response to peptide
B1NLA3E_RS02385	COG1131	(ABC) transporter
B1NLA3E_RS02395	COG3850	Histidine kinase
B1NLA3E_RS02395	COG5002	protein histidine kinase activity
B1NLA3E_RS02400	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS02415	COG1132	(ABC) transporter
B1NLA3E_RS02420	COG1132	(ABC) transporter
B1NLA3E_RS02430	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_RS02440	COG0004	ammonium transporteR
B1NLA3E_RS02455	COG1301	dicarboxylic acid transport
B1NLA3E_RS02460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
B1NLA3E_RS02465	COG3290	protein histidine kinase activity
B1NLA3E_RS02475	COG5002	protein histidine kinase activity
B1NLA3E_RS02480	COG0348	domain, Protein
B1NLA3E_RS02485	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_RS02485	COG2199	diguanylate cyclase activity
B1NLA3E_RS02495	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_RS02500	COG0626	cystathionine gamma-synthase activity
B1NLA3E_RS02530	COG4585	Histidine kinase
B1NLA3E_RS02535	COG2197	response regulator
B1NLA3E_RS02540	COG2244	polysaccharide biosynthetic process
B1NLA3E_RS02545	COG0670	Belongs to the BI1 family
B1NLA3E_RS02550	COG1970	mechanosensitive ion channel activity
B1NLA3E_RS02555	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
B1NLA3E_RS02565	COG2309	aminopeptidase activity
B1NLA3E_RS02570	COG0475	glutathione-regulated potassium exporter activity
B1NLA3E_RS02580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1NLA3E_RS02580	COG0551	DNA topoisomerase type I activity
B1NLA3E_RS02590	COG0024	Methionine aminopeptidase
B1NLA3E_RS02595	COG4840	Belongs to the UPF0435 family
B1NLA3E_RS02605	COG1295	ribonuclease BN
B1NLA3E_RS02620	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_RS02625	COG0477	Major facilitator Superfamily
B1NLA3E_RS02630	COG0387	Pfam Sodium calcium exchanger
B1NLA3E_RS02640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
B1NLA3E_RS02665	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
B1NLA3E_RS02670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
B1NLA3E_RS02675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B1NLA3E_RS02700	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS02705	COG2814	Major facilitator Superfamily
B1NLA3E_RS02710	COG0516	GMP reductase activity
B1NLA3E_RS02710	COG0517	IMP dehydrogenase activity
B1NLA3E_RS02730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
B1NLA3E_RS02740	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS02740	COG1136	(ABC) transporter
B1NLA3E_RS02745	COG4807	Protein conserved in bacteria
B1NLA3E_RS02750	COG2252	PERMEase
B1NLA3E_RS02775	COG1609	Transcriptional regulator
B1NLA3E_RS02780	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B1NLA3E_RS02785	COG0738	Major facilitator superfamily
B1NLA3E_RS02795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_RS02800	COG2610	gluconate transmembrane transporter activity
B1NLA3E_RS02805	COG1929	Belongs to the glycerate kinase type-1 family
B1NLA3E_RS02810	COG3835	regulator
B1NLA3E_RS02845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS02850	COG0765	amino acid transport
B1NLA3E_RS02855	COG1126	abc transporter atp-binding protein
B1NLA3E_RS02870	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS02875	COG2814	Major facilitator Superfamily
B1NLA3E_RS02890	COG3344	reverse transcriptase
B1NLA3E_RS02900	COG3344	reverse transcriptase
B1NLA3E_RS02910	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS02925	COG3344	reverse transcriptase
B1NLA3E_RS02950	COG0454	-acetyltransferase
B1NLA3E_RS02955	COG2819	hydrolase of the alpha beta superfamily
B1NLA3E_RS02975	COG0322	excinuclease ABC activity
B1NLA3E_RS02980	COG1704	LemA family
B1NLA3E_RS02990	COG0217	transcriptional regulatory protein
B1NLA3E_RS03000	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS03005	COG5002	protein histidine kinase activity
B1NLA3E_RS03010	COG1268	BioY protein
B1NLA3E_RS03015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
B1NLA3E_RS03020	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_RS03030	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS03035	COG5002	protein histidine kinase activity
B1NLA3E_RS03040	COG4191	Histidine kinase
B1NLA3E_RS03075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1NLA3E_RS03080	COG5001	Diguanylate cyclase
B1NLA3E_RS03080	COG3300	MHYT domain
B1NLA3E_RS03095	COG3459	Glycosyltransferase 36 associated
B1NLA3E_RS03100	COG2205	protein histidine kinase activity
B1NLA3E_RS03105	COG1328	CTP reductase activity
B1NLA3E_RS03115	COG1309	transcriptional regulator
B1NLA3E_RS03120	COG1131	(ABC) transporter
B1NLA3E_RS03140	COG2270	Major facilitator Superfamily
B1NLA3E_RS03180	COG1113	amino acid transport
B1NLA3E_RS03185	COG0346	lactoylglutathione lyase activity
B1NLA3E_RS03190	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B1NLA3E_RS03195	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
B1NLA3E_RS03215	COG0494	nUDIX hydrolase
B1NLA3E_RS03250	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS03265	COG0697	spore germination
B1NLA3E_RS03295	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1NLA3E_RS03300	COG1304	FMN binding
B1NLA3E_RS03305	COG0549	Belongs to the carbamate kinase family
B1NLA3E_RS03310	COG2508	Transcriptional regulator
B1NLA3E_RS03345	COG1070	Carbohydrate kinase
B1NLA3E_RS03370	COG0778	Nitroreductase
B1NLA3E_RS03385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_RS03395	COG2132	Multicopper oxidase
B1NLA3E_RS03400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1NLA3E_RS03405	COG1742	UPF0060 membrane protein
B1NLA3E_RS03440	COG1183	phosphatidylcholine synthase activity
B1NLA3E_RS03445	COG2252	PERMEase
B1NLA3E_RS03450	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
B1NLA3E_RS03470	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS03490	COG1585	Membrane protein implicated in regulation of membrane protease activity
B1NLA3E_RS03495	COG2268	Band 7 protein
B1NLA3E_RS03500	COG1609	Transcriptional regulator
B1NLA3E_RS03505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_RS03515	COG1129	ABC transporter
B1NLA3E_RS03520	COG1172	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_RS03525	COG1879	ABC-type sugar transport system periplasmic component
B1NLA3E_RS03550	COG1132	(ABC) transporter
B1NLA3E_RS03555	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS03565	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_RS03585	COG4134	Bacterial extracellular solute-binding protein
B1NLA3E_RS03595	COG4149	molybdate abc transporter
B1NLA3E_RS03600	COG3842	ATPase activity
B1NLA3E_RS03610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1NLA3E_RS03625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B1NLA3E_RS03630	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
B1NLA3E_RS03635	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
B1NLA3E_RS03635	COG0028	Belongs to the TPP enzyme family
B1NLA3E_RS03675	COG1988	membrane-bound metal-dependent
B1NLA3E_RS03680	COG1194	a g-specific adenine glycosylase
B1NLA3E_RS03690	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS03705	COG3557	Belongs to the UPF0374 family
B1NLA3E_RS03710	COG1132	(ABC) transporter
B1NLA3E_RS03720	COG5577	PFAM Coat F domain
B1NLA3E_RS03725	COG4129	membrane
B1NLA3E_RS03730	COG0067	glutamate synthase
B1NLA3E_RS03730	COG0069	glutamate synthase activity
B1NLA3E_RS03730	COG0070	glutamate synthase
B1NLA3E_RS03735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1NLA3E_RS03740	COG4555	ABC transporter
B1NLA3E_RS03760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B1NLA3E_RS03765	COG2096	Adenosyltransferase
B1NLA3E_RS03770	COG0735	belongs to the Fur family
B1NLA3E_RS03895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B1NLA3E_RS03905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B1NLA3E_RS03910	COG2766	serine protein kinase
B1NLA3E_RS03920	COG2814	Major facilitator Superfamily
B1NLA3E_RS03925	COG1809	phosphosulfolactate synthase activity
B1NLA3E_RS03930	COG0406	alpha-ribazole phosphatase activity
B1NLA3E_RS03935	COG0175	sulfate reduction
B1NLA3E_RS03940	COG2046	Belongs to the sulfate adenylyltransferase family
B1NLA3E_RS03945	COG0529	Catalyzes the synthesis of activated sulfate
B1NLA3E_RS03950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS03955	COG2718	Belongs to the UPF0229 family
B1NLA3E_RS03990	COG0243	molybdopterin cofactor binding
B1NLA3E_RS04015	COG2223	nitrite transmembrane transporter activity
B1NLA3E_RS04020	COG4585	Histidine kinase
B1NLA3E_RS04025	COG2197	response regulator
B1NLA3E_RS04045	COG0628	permease
B1NLA3E_RS04060	COG0306	phosphate transporter
B1NLA3E_RS04065	COG1392	Phosphate transport regulator
B1NLA3E_RS04070	COG0564	pseudouridine synthase activity
B1NLA3E_RS04080	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS04090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B1NLA3E_RS04105	COG2719	SpoVR family
B1NLA3E_RS04125	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_RS04130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B1NLA3E_RS04135	COG1253	flavin adenine dinucleotide binding
B1NLA3E_RS04150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1NLA3E_RS04155	COG3852	Histidine kinase
B1NLA3E_RS04180	COG0702	epimerase
B1NLA3E_RS04195	COG3842	ATPase activity
B1NLA3E_RS04200	COG2508	Transcriptional regulator
B1NLA3E_RS04210	COG0189	ligase activity
B1NLA3E_RS04220	COG0561	phosphatase activity
B1NLA3E_RS04225	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS04235	COG4152	abc transporter atp-binding protein
B1NLA3E_RS04240	COG1668	transmembrane transport
B1NLA3E_RS04245	COG0420	3'-5' exonuclease activity
B1NLA3E_RS04250	COG4717	serine-type aminopeptidase activity
B1NLA3E_RS04265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_RS04280	COG1846	Transcriptional regulator
B1NLA3E_RS04300	COG0537	adenosine 5'-monophosphoramidase activity
B1NLA3E_RS04305	COG1131	(ABC) transporter
B1NLA3E_RS04310	COG4473	ABC transporter
B1NLA3E_RS04325	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_RS04330	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_RS04335	COG0747	negative chemotaxis
B1NLA3E_RS04340	COG0601	transmembrane transport
B1NLA3E_RS04345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_RS04355	COG5002	protein histidine kinase activity
B1NLA3E_RS04360	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS04390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS04395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS04400	COG3069	C4-dicarboxylate transmembrane transporter activity
B1NLA3E_RS04405	COG2329	Antibiotic biosynthesis monooxygenase
B1NLA3E_RS04415	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
B1NLA3E_RS04420	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
B1NLA3E_RS04425	COG1309	transcriptional regulator
B1NLA3E_RS04430	COG1511	domain protein
B1NLA3E_RS04435	COG1234	tRNA 3'-trailer cleavage
B1NLA3E_RS04440	COG0095	Lipoate-protein ligase
B1NLA3E_RS04445	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS04455	COG4120	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_RS04460	COG1122	ATPase activity
B1NLA3E_RS04470	COG1802	Transcriptional regulator
B1NLA3E_RS04475	COG2084	Dehydrogenase
B1NLA3E_RS04505	COG0697	spore germination
B1NLA3E_RS04510	COG0604	alcohol dehydrogenase
B1NLA3E_RS04525	COG1114	Component of the transport system for branched-chain amino acids
B1NLA3E_RS04530	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_RS04540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B1NLA3E_RS04550	COG0501	Belongs to the peptidase M48B family
B1NLA3E_RS04560	COG4903	ComK protein
B1NLA3E_RS04575	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_RS04590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_RS04600	COG5577	PFAM Coat F domain
B1NLA3E_RS04615	COG0410	ABC transporter
B1NLA3E_RS04620	COG0559	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_RS04630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_RS04635	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS04660	COG1113	amino acid transport
B1NLA3E_RS04665	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B1NLA3E_RS04665	COG2508	Transcriptional regulator
B1NLA3E_RS04670	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_RS04675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B1NLA3E_RS04680	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS04690	COG2308	Evidence 4 Homologs of previously reported genes of
B1NLA3E_RS04700	COG1305	Transglutaminase-like
B1NLA3E_RS04705	COG1268	BioY protein
B1NLA3E_RS04725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B1NLA3E_RS04740	COG0367	asparagine synthase
B1NLA3E_RS04770	COG1132	(ABC) transporter
B1NLA3E_RS04775	COG3944	biosynthesis protein
B1NLA3E_RS04780	COG0489	protein tyrosine kinase activity
B1NLA3E_RS04790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_RS04800	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS04805	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_RS04810	COG0463	Glycosyl transferase, family 2
B1NLA3E_RS04810	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
B1NLA3E_RS04820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_RS04825	COG0110	maltose O-acetyltransferase activity
B1NLA3E_RS04830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1NLA3E_RS04855	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_RS04870	COG1442	glycosyl transferase family 8
B1NLA3E_RS04870	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS04895	COG4372	Transposase
B1NLA3E_RS04910	COG1132	(ABC) transporter
B1NLA3E_RS04935	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
B1NLA3E_RS04940	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS04995	COG0367	asparagine synthase
B1NLA3E_RS05005	COG1874	Beta-galactosidase
B1NLA3E_RS05005	COG0366	Alpha amylase catalytic
B1NLA3E_RS05010	COG1666	GTP binding
B1NLA3E_RS05015	COG2996	Protein conserved in bacteria
B1NLA3E_RS05020	COG1307	EDD domain protein, DegV family
B1NLA3E_RS05025	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS05040	COG0561	phosphatase activity
B1NLA3E_RS05045	COG2151	metal-sulfur cluster biosynthetic enzyme
B1NLA3E_RS05055	COG1131	(ABC) transporter
B1NLA3E_RS05060	COG1511	domain protein
B1NLA3E_RS05060	COG0842	Transport permease protein
B1NLA3E_RS05065	COG0842	Transport permease protein
B1NLA3E_RS05070	COG0535	radical SAM domain protein
B1NLA3E_RS05075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS05080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_RS05085	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
B1NLA3E_RS05090	COG0303	'Molybdopterin
B1NLA3E_RS05095	COG1763	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_RS05105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS05110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
B1NLA3E_RS05120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
B1NLA3E_RS05140	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
B1NLA3E_RS05160	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_RS05185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_RS05190	COG5504	Zn-dependent protease
B1NLA3E_RS05200	COG0180	Tryptophanyl-tRNA synthetase
B1NLA3E_RS05205	COG4166	transmembrane transport
B1NLA3E_RS05210	COG0601	transmembrane transport
B1NLA3E_RS05215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_RS05220	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_RS05225	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_RS05235	COG1393	Belongs to the ArsC family
B1NLA3E_RS05240	COG4862	establishment of competence for transformation
B1NLA3E_RS05245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_RS05255	COG1164	Oligoendopeptidase f
B1NLA3E_RS05265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1NLA3E_RS05270	COG2346	COG2346, Truncated hemoglobins
B1NLA3E_RS05275	COG4116	CYTH
B1NLA3E_RS05280	COG2357	RelA SpoT domain protein
B1NLA3E_RS05290	COG0564	pseudouridine synthase activity
B1NLA3E_RS05295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B1NLA3E_RS05300	COG0475	glutathione-regulated potassium exporter activity
B1NLA3E_RS05300	COG0569	domain protein
B1NLA3E_RS05305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B1NLA3E_RS05325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_RS05340	COG0210	DNA helicase
B1NLA3E_RS05345	COG2153	protein acetylation
B1NLA3E_RS05350	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
B1NLA3E_RS05365	COG0247	lactate metabolic process
B1NLA3E_RS05370	COG1139	Iron-sulfur cluster binding protein
B1NLA3E_RS05375	COG1556	Lactate utilization protein
B1NLA3E_RS05380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1NLA3E_RS05380	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_RS05430	COG0463	Glycosyl transferase, family 2
B1NLA3E_RS05430	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS05455	COG0702	epimerase
B1NLA3E_RS05460	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
B1NLA3E_RS05465	COG1846	Transcriptional regulator
B1NLA3E_RS05490	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
B1NLA3E_RS05500	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1NLA3E_RS05505	COG2814	Major facilitator Superfamily
B1NLA3E_RS05510	COG2814	Major facilitator Superfamily
B1NLA3E_RS05515	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS05525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1NLA3E_RS05530	COG2151	metal-sulfur cluster biosynthetic enzyme
B1NLA3E_RS05540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
B1NLA3E_RS05550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B1NLA3E_RS05560	COG1191	sigma factor activity
B1NLA3E_RS05575	COG0247	lactate metabolic process
B1NLA3E_RS05580	COG0277	FAD linked oxidase domain protein
B1NLA3E_RS05585	COG3835	regulator
B1NLA3E_RS05610	COG1620	l-lactate permease
B1NLA3E_RS05615	COG2186	Transcriptional regulator
B1NLA3E_RS05620	COG0247	lactate metabolic process
B1NLA3E_RS05625	COG1139	Iron-sulfur cluster binding protein
B1NLA3E_RS05630	COG1556	Lactate utilization protein
B1NLA3E_RS05665	COG5002	protein histidine kinase activity
B1NLA3E_RS05675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1NLA3E_RS05680	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_RS05685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B1NLA3E_RS05690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B1NLA3E_RS05705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS05710	COG0644	oxidoreductase
B1NLA3E_RS05725	COG2972	Histidine kinase
B1NLA3E_RS05730	COG2201	protein-glutamate methylesterase activity
B1NLA3E_RS05740	COG1175	transmembrane transport
B1NLA3E_RS05765	COG0671	phosphoesterase, PA-phosphatase related
B1NLA3E_RS05775	COG1309	transcriptional regulator
B1NLA3E_RS05785	COG2318	DinB family
B1NLA3E_RS05790	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS05795	COG5002	protein histidine kinase activity
B1NLA3E_RS05800	COG1136	(ABC) transporter
B1NLA3E_RS05805	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS05840	COG0697	spore germination
B1NLA3E_RS05855	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS05860	COG1136	(ABC) transporter
B1NLA3E_RS05870	COG3850	Histidine kinase
B1NLA3E_RS05870	COG5002	protein histidine kinase activity
B1NLA3E_RS05900	COG0456	acetyltransferase
B1NLA3E_RS05905	COG0456	acetyltransferase
B1NLA3E_RS05915	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_RS05935	COG2207	Transcriptional regulator
B1NLA3E_RS05940	COG0667	Aldo Keto reductase
B1NLA3E_RS05945	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_RS05950	COG2223	nitrite transmembrane transporter activity
B1NLA3E_RS05955	COG1846	Transcriptional regulator
B1NLA3E_RS05965	COG3949	Membrane
B1NLA3E_RS05975	COG4873	Protein conserved in bacteria
B1NLA3E_RS05985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_RS05990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1NLA3E_RS06000	COG2084	Dehydrogenase
B1NLA3E_RS06005	COG0436	Aminotransferase
B1NLA3E_RS06010	COG0598	Magnesium transport protein CorA
B1NLA3E_RS06030	COG1408	metallophosphoesterase
B1NLA3E_RS06035	COG4990	cell redox homeostasis
B1NLA3E_RS06040	COG2200	EAL domain
B1NLA3E_RS06060	COG2323	membrane
B1NLA3E_RS06080	COG4703	Protein of unknown function (DUF1797)
B1NLA3E_RS06085	COG0517	IMP dehydrogenase activity
B1NLA3E_RS06090	COG2814	Major facilitator Superfamily
B1NLA3E_RS06095	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS06105	COG1473	amidohydrolase
B1NLA3E_RS06110	COG0450	alkyl hydroperoxide reductase
B1NLA3E_RS06120	COG0569	domain protein
B1NLA3E_RS06125	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_RS06130	COG5503	Protein of unknown function (DUF1447)
B1NLA3E_RS06135	COG0561	phosphatase activity
B1NLA3E_RS06140	COG0242	peptide deformylase activity
B1NLA3E_RS06150	COG0497	DNA recombination
B1NLA3E_RS06160	COG0022	dehydrogenase e1 component
B1NLA3E_RS06195	COG1982	Orn Lys Arg decarboxylase major
B1NLA3E_RS06205	COG4476	Belongs to the UPF0223 family
B1NLA3E_RS06210	COG4493	Belongs to the UPF0637 family
B1NLA3E_RS06220	COG0483	inositol monophosphate 1-phosphatase activity
B1NLA3E_RS06230	COG1217	gtp-binding protein TYPA
B1NLA3E_RS06265	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
B1NLA3E_RS06270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
B1NLA3E_RS06275	COG4838	Belongs to the UPF0358 family
B1NLA3E_RS06280	COG0772	Belongs to the SEDS family
B1NLA3E_RS06285	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
B1NLA3E_RS06290	COG1612	heme a metabolic process
B1NLA3E_RS06320	COG3336	cytochrome c oxidase
B1NLA3E_RS06330	COG0628	permease
B1NLA3E_RS06345	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
B1NLA3E_RS06355	COG2340	Cysteine-rich secretory protein family
B1NLA3E_RS06385	COG3679	Belongs to the UPF0342 family
B1NLA3E_RS06390	COG4471	UPF0298 protein
B1NLA3E_RS06405	COG0742	ribosomal rna small subunit methyltransferase
B1NLA3E_RS06410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
B1NLA3E_RS06415	COG3314	Sporulation integral membrane protein YlbJ
B1NLA3E_RS06420	COG1752	Esterase of the alpha-beta hydrolase superfamily
B1NLA3E_RS06425	COG3480	Lon protease (S16) C-terminal proteolytic domain
B1NLA3E_RS06430	COG1323	Belongs to the UPF0348 family
B1NLA3E_RS06435	COG1399	metal-binding, possibly nucleic acid-binding protein
B1NLA3E_RS06440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
B1NLA3E_RS06445	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS06455	COG0454	-acetyltransferase
B1NLA3E_RS06460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
B1NLA3E_RS06470	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
B1NLA3E_RS06475	COG2001	Belongs to the MraZ family
B1NLA3E_RS06480	COG0275	rRNA processing
B1NLA3E_RS06485	COG4839	cell division protein FtsL
B1NLA3E_RS06490	COG0768	penicillin binding
B1NLA3E_RS06495	COG0768	penicillin binding
B1NLA3E_RS06510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1NLA3E_RS06520	COG0772	Belongs to the SEDS family
B1NLA3E_RS06530	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B1NLA3E_RS06535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B1NLA3E_RS06540	COG3879	Bacterial protein of unknown function (DUF881)
B1NLA3E_RS06545	COG3879	Bacterial protein of unknown function (DUF881)
B1NLA3E_RS06550	COG3856	small basic protein
B1NLA3E_RS06555	COG0849	cell division
B1NLA3E_RS06560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B1NLA3E_RS06570	COG1191	sigma factor activity
B1NLA3E_RS06580	COG1191	sigma factor activity
B1NLA3E_RS06585	COG1873	PFAM PRC-barrel domain
B1NLA3E_RS06590	COG1496	oxidoreductase activity
B1NLA3E_RS06595	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B1NLA3E_RS06600	COG1799	cell septum assembly
B1NLA3E_RS06605	COG0762	integral membrane protein
B1NLA3E_RS06610	COG2302	S4 RNA-binding domain
B1NLA3E_RS06615	COG3599	regulation of cell shape
B1NLA3E_RS06620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B1NLA3E_RS06625	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B1NLA3E_RS06635	COG0564	pseudouridine synthase activity
B1NLA3E_RS06640	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
B1NLA3E_RS06670	COG0543	2 iron, 2 sulfur cluster binding
B1NLA3E_RS06675	COG0167	dihydroorotate dehydrogenase activity
B1NLA3E_RS06680	COG0284	orotidine-5'-phosphate decarboxylase activity
B1NLA3E_RS06685	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
B1NLA3E_RS06700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1NLA3E_RS06705	COG1561	YicC-like family, N-terminal region
B1NLA3E_RS06715	COG0194	GDP metabolic process
B1NLA3E_RS06725	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1NLA3E_RS06730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B1NLA3E_RS06740	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1NLA3E_RS06745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B1NLA3E_RS06745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B1NLA3E_RS06750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1NLA3E_RS06755	COG0631	protein serine/threonine phosphatase activity
B1NLA3E_RS06760	COG2815	serine threonine protein kinase
B1NLA3E_RS06760	COG0515	serine threonine protein kinase
B1NLA3E_RS06765	COG1162	GTPase activity
B1NLA3E_RS06770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1NLA3E_RS06775	COG1564	THIamine pyrophosphokinase
B1NLA3E_RS06790	COG0227	Belongs to the bacterial ribosomal protein bL28 family
B1NLA3E_RS06795	COG1302	Protein conserved in bacteria
B1NLA3E_RS06800	COG1461	Dihydroxyacetone kinase
B1NLA3E_RS06805	COG1760	l-serine dehydratase
B1NLA3E_RS06810	COG1760	l-serine dehydratase
B1NLA3E_RS06815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B1NLA3E_RS06820	COG1349	DNA-binding transcription factor activity
B1NLA3E_RS06825	COG0416	fatty acid biosynthetic process
B1NLA3E_RS06830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B1NLA3E_RS06835	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS06840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B1NLA3E_RS06845	COG0571	ribonuclease III activity
B1NLA3E_RS06850	COG1196	nuclear chromosome segregation
B1NLA3E_RS06855	COG0552	protein localization to endoplasmic reticulum
B1NLA3E_RS06875	COG0754	glutathionylspermidine amidase activity
B1NLA3E_RS06880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1NLA3E_RS06885	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
B1NLA3E_RS06890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B1NLA3E_RS06895	COG0228	four-way junction DNA binding
B1NLA3E_RS06900	COG1837	Belongs to the UPF0109 family
B1NLA3E_RS06910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B1NLA3E_RS06915	COG0336	Belongs to the RNA methyltransferase TrmD family
B1NLA3E_RS06945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
B1NLA3E_RS06950	COG0758	DNA mediated transformation
B1NLA3E_RS06955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1NLA3E_RS06965	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
B1NLA3E_RS06970	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_RS06975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
B1NLA3E_RS06985	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B1NLA3E_RS07005	COG0528	UMP kinase activity
B1NLA3E_RS07010	COG0233	cytoplasmic translational termination
B1NLA3E_RS07020	COG4589	Belongs to the CDS family
B1NLA3E_RS07025	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
B1NLA3E_RS07030	COG0750	zinc metalloprotease
B1NLA3E_RS07040	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_RS07045	COG0779	Required for maturation of 30S ribosomal subunits
B1NLA3E_RS07050	COG0195	Participates in both transcription termination and antitermination
B1NLA3E_RS07055	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B1NLA3E_RS07060	COG1358	cellular component organization or biogenesis
B1NLA3E_RS07070	COG1550	Protein conserved in bacteria
B1NLA3E_RS07075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
B1NLA3E_RS07080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B1NLA3E_RS07085	COG0196	riboflavin kinase activity
B1NLA3E_RS07090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
B1NLA3E_RS07095	COG1185	polyribonucleotide nucleotidyltransferase activity
B1NLA3E_RS07100	COG0726	polysaccharide deacetylase
B1NLA3E_RS07105	COG0612	Peptidase, M16
B1NLA3E_RS07110	COG1873	PFAM PRC-barrel domain
B1NLA3E_RS07115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_RS07120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B1NLA3E_RS07125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
B1NLA3E_RS07130	COG0527	aspartate kinase activity
B1NLA3E_RS07135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1NLA3E_RS07140	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_RS07145	COG0740	serine-type endopeptidase activity
B1NLA3E_RS07155	COG4980	gas vesicle protein
B1NLA3E_RS07155	COG1674	ftsk spoiiie
B1NLA3E_RS07160	COG2188	Transcriptional regulator
B1NLA3E_RS07165	COG1744	ABC transporter substrate-binding protein PnrA-like
B1NLA3E_RS07170	COG3845	ABC transporter
B1NLA3E_RS07175	COG4603	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_RS07180	COG1079	Belongs to the binding-protein-dependent transport system permease family
B1NLA3E_RS07185	COG0612	Peptidase, M16
B1NLA3E_RS07190	COG0612	Peptidase, M16
B1NLA3E_RS07195	COG0300	oxidoreductase activity
B1NLA3E_RS07210	COG1426	Protein conserved in bacteria
B1NLA3E_RS07215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1NLA3E_RS07220	COG1058	Belongs to the CinA family
B1NLA3E_RS07220	COG1546	Belongs to the CinA family
B1NLA3E_RS07225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
B1NLA3E_RS07230	COG1418	mRNA catabolic process
B1NLA3E_RS07235	COG1692	metallophosphoesterase
B1NLA3E_RS07240	COG2359	stage V sporulation protein S
B1NLA3E_RS07245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
B1NLA3E_RS07245	COG0674	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_RS07250	COG1013	pyruvate-flavodoxin oxidoreductase activity
B1NLA3E_RS07255	COG1349	DNA-binding transcription factor activity
B1NLA3E_RS07260	COG1105	Belongs to the carbohydrate kinase PfkB family
B1NLA3E_RS07265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_RS07265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_RS07265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_RS07270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1NLA3E_RS07275	COG4550	Control of competence regulator ComK, YlbF/YmcA
B1NLA3E_RS07290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
B1NLA3E_RS07295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B1NLA3E_RS07305	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_RS07310	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
B1NLA3E_RS07315	COG1923	regulation of RNA biosynthetic process
B1NLA3E_RS07325	COG0464	growth
B1NLA3E_RS07330	COG2860	membrane
B1NLA3E_RS07335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B1NLA3E_RS07340	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
B1NLA3E_RS07345	COG0789	Transcriptional regulator
B1NLA3E_RS07350	COG0174	glutamine synthetase
B1NLA3E_RS07355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B1NLA3E_RS07360	COG1388	LysM domain
B1NLA3E_RS07365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
B1NLA3E_RS07375	COG0477	Major facilitator Superfamily
B1NLA3E_RS07385	COG1271	oxidase subunit
B1NLA3E_RS07390	COG1294	oxidase, subunit
B1NLA3E_RS07400	COG3763	UPF0154 protein
B1NLA3E_RS07405	COG0791	NLP P60 protein
B1NLA3E_RS07405	COG3883	PFAM NLP P60 protein
B1NLA3E_RS07410	COG1132	(ABC) transporter
B1NLA3E_RS07415	COG1132	(ABC) transporter
B1NLA3E_RS07425	COG0785	Cytochrome C biogenesis protein
B1NLA3E_RS07430	COG2201	protein-glutamate methylesterase activity
B1NLA3E_RS07435	COG4846	Membrane protein involved in cytochrome C biogenesis
B1NLA3E_RS07475	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_RS07535	COG0277	FAD linked oxidase domain protein
B1NLA3E_RS07555	COG1136	(ABC) transporter
B1NLA3E_RS07560	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_RS07570	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS07570	COG1454	alcohol dehydrogenase
B1NLA3E_RS07580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B1NLA3E_RS07585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_RS07605	COG1131	(ABC) transporter
B1NLA3E_RS07635	COG5002	protein histidine kinase activity
B1NLA3E_RS07650	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS07655	COG0768	penicillin binding
B1NLA3E_RS07665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1NLA3E_RS07670	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
B1NLA3E_RS07675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
B1NLA3E_RS07680	COG3639	organic phosphonate transmembrane transporter activity
B1NLA3E_RS07690	COG1309	transcriptional regulator
B1NLA3E_RS07700	COG0667	Aldo Keto reductase
B1NLA3E_RS07710	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1NLA3E_RS07715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1NLA3E_RS07720	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS07725	COG2186	Transcriptional regulator
B1NLA3E_RS07730	COG1063	alcohol dehydrogenase
B1NLA3E_RS07740	COG0205	6-phosphofructokinase activity
B1NLA3E_RS07745	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS07750	COG5002	protein histidine kinase activity
B1NLA3E_RS07760	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS07770	COG1136	(ABC) transporter
B1NLA3E_RS07780	COG1113	amino acid transport
B1NLA3E_RS07815	COG0346	lactoylglutathione lyase activity
B1NLA3E_RS07830	COG3384	dioxygenase
B1NLA3E_RS07870	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_RS07875	COG1346	cytolysis
B1NLA3E_RS07880	COG1380	Effector of murein hydrolase LrgA
B1NLA3E_RS07885	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B1NLA3E_RS07910	COG1113	amino acid transport
B1NLA3E_RS07915	COG0672	)-iron permease
B1NLA3E_RS07930	COG1136	(ABC) transporter
B1NLA3E_RS07930	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS07935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B1NLA3E_RS07940	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS07945	COG5002	protein histidine kinase activity
B1NLA3E_RS07945	COG3850	Histidine kinase
B1NLA3E_RS07950	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS07955	COG2271	Major facilitator Superfamily
B1NLA3E_RS07965	COG0644	oxidoreductase
B1NLA3E_RS07975	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS07980	COG2086	electron transfer activity
B1NLA3E_RS07985	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS07990	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS07995	COG2271	Major facilitator Superfamily
B1NLA3E_RS08015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS08030	COG1376	ErfK ybiS ycfS ynhG family protein
B1NLA3E_RS08040	COG0322	excinuclease ABC activity
B1NLA3E_RS08045	COG4191	Histidine kinase
B1NLA3E_RS08080	COG0419	ATPase involved in DNA repair
B1NLA3E_RS08090	COG1252	NADH dehydrogenase
B1NLA3E_RS08095	COG0535	radical SAM domain protein
B1NLA3E_RS08100	COG2814	Major facilitator Superfamily
B1NLA3E_RS08120	COG2871	sodium ion transport
B1NLA3E_RS08125	COG1414	Transcriptional regulator
B1NLA3E_RS08150	COG0004	ammonium transporteR
B1NLA3E_RS08155	COG0196	riboflavin kinase activity
B1NLA3E_RS08175	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS08180	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS08185	COG0439	Biotin carboxylase
B1NLA3E_RS08190	COG0511	ligase activity, forming carbon-carbon bonds
B1NLA3E_RS08195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1NLA3E_RS08200	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS08205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1NLA3E_RS08210	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_RS08215	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_RS08220	COG0352	thiamine-phosphate diphosphorylase activity
B1NLA3E_RS08230	COG2104	thiamine diphosphate biosynthetic process
B1NLA3E_RS08235	COG2022	thiamine diphosphate biosynthetic process
B1NLA3E_RS08240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_RS08255	COG3437	response regulator, receiver
B1NLA3E_RS08255	COG2770	Histidine kinase
B1NLA3E_RS08260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_RS08265	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B1NLA3E_RS08275	COG0681	Belongs to the peptidase S26 family
B1NLA3E_RS08290	COG5583	Uncharacterized small protein (DUF2292)
B1NLA3E_RS08295	COG1116	anion transmembrane transporter activity
B1NLA3E_RS08300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_RS08305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS08310	COG0431	NADPH-dependent FMN reductase
B1NLA3E_RS08315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS08325	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B1NLA3E_RS08330	COG1119	ATPase activity
B1NLA3E_RS08340	COG1714	RDD family
B1NLA3E_RS08350	COG0175	sulfate reduction
B1NLA3E_RS08355	COG0306	phosphate transporter
B1NLA3E_RS08365	COG0529	Catalyzes the synthesis of activated sulfate
B1NLA3E_RS08370	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_RS08405	COG2340	Cysteine-rich secretory protein family
B1NLA3E_RS08410	COG1363	Peptidase, m42
B1NLA3E_RS08420	COG1368	sulfuric ester hydrolase activity
B1NLA3E_RS08450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS08460	COG0084	hydrolase, TatD family'
B1NLA3E_RS08490	COG0604	alcohol dehydrogenase
B1NLA3E_RS08495	COG2116	formate transmembrane transporter activity
B1NLA3E_RS08505	COG1309	transcriptional regulator
B1NLA3E_RS08565	COG0561	phosphatase activity
B1NLA3E_RS08575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B1NLA3E_RS08585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1NLA3E_RS08595	COG0668	transmembrane transport
B1NLA3E_RS08605	COG0531	amino acid
B1NLA3E_RS08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_RS08625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_RS08635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B1NLA3E_RS08645	COG4208	sulfate ABC transporter
B1NLA3E_RS08655	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B1NLA3E_RS08680	COG0697	spore germination
B1NLA3E_RS08685	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B1NLA3E_RS08695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_RS08700	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B1NLA3E_RS08705	COG1116	anion transmembrane transporter activity
B1NLA3E_RS08710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS08715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_RS08720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_RS08740	COG2323	membrane
B1NLA3E_RS08745	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS08750	COG0070	glutamate synthase
B1NLA3E_RS08750	COG0069	glutamate synthase activity
B1NLA3E_RS08750	COG0067	glutamate synthase
B1NLA3E_RS08755	COG0493	'glutamate synthase
B1NLA3E_RS08765	COG1388	LysM domain
B1NLA3E_RS08765	COG3942	CHAP domain
B1NLA3E_RS08775	COG2171	N-acyltransferase activity
B1NLA3E_RS08780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS08785	COG1346	cytolysis
B1NLA3E_RS08795	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS08805	COG1396	sequence-specific DNA binding
B1NLA3E_RS08810	COG0252	asparaginase activity
B1NLA3E_RS08820	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
B1NLA3E_RS08830	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
B1NLA3E_RS08840	COG1408	metallophosphoesterase
B1NLA3E_RS08845	COG3541	Predicted nucleotidyltransferase
B1NLA3E_RS08850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_RS08850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B1NLA3E_RS08850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_RS08860	COG2135	peptidase activity
B1NLA3E_RS08865	COG0531	amino acid
B1NLA3E_RS08870	COG1278	Cold shock
B1NLA3E_RS08885	COG3971	2-oxopent-4-enoate hydratase activity
B1NLA3E_RS08935	COG2871	sodium ion transport
B1NLA3E_RS08955	COG1914	H( )-stimulated, divalent metal cation uptake system
B1NLA3E_RS08960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
B1NLA3E_RS08990	COG0596	Alpha beta hydrolase
B1NLA3E_RS09000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_RS09005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_RS09010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_RS09015	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_RS09020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS09025	COG0765	amino acid transport
B1NLA3E_RS09030	COG1126	abc transporter atp-binding protein
B1NLA3E_RS09035	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS09040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_RS09055	COG0686	Belongs to the AlaDH PNT family
B1NLA3E_RS09065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS09070	COG0765	amino acid transport
B1NLA3E_RS09075	COG1126	abc transporter atp-binding protein
B1NLA3E_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS09095	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B1NLA3E_RS09100	COG0561	phosphatase activity
B1NLA3E_RS09105	COG1349	DNA-binding transcription factor activity
B1NLA3E_RS09115	COG1858	cytochrome C peroxidase
B1NLA3E_RS09135	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS09150	COG5434	Belongs to the glycosyl hydrolase 28 family
B1NLA3E_RS09175	COG0798	PFAM Bile acid sodium symporter
B1NLA3E_RS09180	COG0640	Transcriptional regulator
B1NLA3E_RS09185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B1NLA3E_RS09205	COG2226	methyltransferase
B1NLA3E_RS09230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_RS09240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS09245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS09250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B1NLA3E_RS09260	COG0454	-acetyltransferase
B1NLA3E_RS09260	COG0456	acetyltransferase
B1NLA3E_RS09265	COG1473	amidohydrolase
B1NLA3E_RS09275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_RS09280	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_RS09285	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_RS09290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS09300	COG3655	Transcriptional regulator
B1NLA3E_RS09315	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS09330	COG0196	riboflavin kinase activity
B1NLA3E_RS09360	COG0730	response to heat
B1NLA3E_RS09365	COG2733	membrane
B1NLA3E_RS09375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_RS09385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS09390	COG0765	amino acid transport
B1NLA3E_RS09395	COG1126	abc transporter atp-binding protein
B1NLA3E_RS09400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_RS09405	COG0194	GDP metabolic process
B1NLA3E_RS09410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B1NLA3E_RS09415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1NLA3E_RS09420	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1NLA3E_RS09430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B1NLA3E_RS09440	COG0488	(ABC) transporter
B1NLA3E_RS09445	COG1231	oxidoreductase activity
B1NLA3E_RS09480	COG4319	ketosteroid isomerase
B1NLA3E_RS09490	COG0156	8-amino-7-oxononanoate synthase activity
B1NLA3E_RS09505	COG0004	ammonium transporteR
B1NLA3E_RS09510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B1NLA3E_RS09510	COG0517	IMP dehydrogenase activity
B1NLA3E_RS09515	COG2723	6-phospho-beta-galactosidase activity
B1NLA3E_RS09520	COG2814	Major facilitator Superfamily
B1NLA3E_RS09535	COG3655	Transcriptional regulator
B1NLA3E_RS09540	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS09560	COG1846	Transcriptional regulator
B1NLA3E_RS09565	COG0386	Belongs to the glutathione peroxidase family
B1NLA3E_RS09575	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
B1NLA3E_RS09580	COG4085	toxin activity
B1NLA3E_RS09580	COG1525	nuclease
B1NLA3E_RS09580	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_RS09585	COG0137	argininosuccinate synthase activity
B1NLA3E_RS09605	COG2755	lipolytic protein G-D-S-L family
B1NLA3E_RS09605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
B1NLA3E_RS09645	COG2364	Membrane
B1NLA3E_RS09655	COG1414	Transcriptional regulator
B1NLA3E_RS09675	COG0006	proline dipeptidase activity
B1NLA3E_RS09695	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS09700	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS09705	COG4638	Rieske (2fe-2S)
B1NLA3E_RS09725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS09740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_RS09750	COG0196	riboflavin kinase activity
B1NLA3E_RS09780	COG1942	4-Oxalocrotonate Tautomerase
B1NLA3E_RS09820	COG2176	DNA-directed DNA polymerase activity
B1NLA3E_RS09850	COG1061	Type III restriction enzyme res subunit
B1NLA3E_RS09855	COG0537	adenosine 5'-monophosphoramidase activity
B1NLA3E_RS09880	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_RS09915	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_RS09930	COG3275	phosphorelay sensor kinase activity
B1NLA3E_RS09935	COG3279	Response regulator of the LytR AlgR family
B1NLA3E_RS09940	COG2223	nitrite transmembrane transporter activity
B1NLA3E_RS09990	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS09995	COG2249	NAD(P)H dehydrogenase (quinone) activity
B1NLA3E_RS10010	COG1733	regulation of RNA biosynthetic process
B1NLA3E_RS10020	COG2814	Major facilitator Superfamily
B1NLA3E_RS10025	COG1309	transcriptional regulator
B1NLA3E_RS10100	COG3773	Cell wall hydrolase
B1NLA3E_RS10110	COG0662	Cupin 2, conserved barrel domain protein
B1NLA3E_RS10135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS10155	COG2873	o-acetylhomoserine
B1NLA3E_RS10160	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS10180	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_RS10195	COG0531	amino acid
B1NLA3E_RS10210	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B1NLA3E_RS10215	COG0569	domain protein
B1NLA3E_RS10230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1NLA3E_RS10235	COG2818	Glycosylase
B1NLA3E_RS10240	COG0531	amino acid
B1NLA3E_RS10245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_RS10255	COG2204	response regulator
B1NLA3E_RS10260	COG3852	Histidine kinase
B1NLA3E_RS10270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_RS10280	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_RS10285	COG2910	NAD(P)H-binding
B1NLA3E_RS10290	COG2249	NAD(P)H dehydrogenase (quinone) activity
B1NLA3E_RS10295	COG3275	phosphorelay sensor kinase activity
B1NLA3E_RS10305	COG1966	Carbon starvation protein
B1NLA3E_RS10320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B1NLA3E_RS10345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B1NLA3E_RS10375	COG1090	epimerase
B1NLA3E_RS10380	COG1454	alcohol dehydrogenase
B1NLA3E_RS10380	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS10385	COG0701	Predicted permease
B1NLA3E_RS10390	COG3689	TIGRFAM TIGR03943 family protein
B1NLA3E_RS10395	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1NLA3E_RS10405	COG3584	3D domain protein
B1NLA3E_RS10405	COG3583	domain protein
B1NLA3E_RS10440	COG2186	Transcriptional regulator
B1NLA3E_RS10455	COG2822	iron ion transport
B1NLA3E_RS10460	COG2837	iron assimilation
B1NLA3E_RS10480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B1NLA3E_RS10485	COG0390	transport system, permease component
B1NLA3E_RS10500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_RS10505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS10510	COG1116	anion transmembrane transporter activity
B1NLA3E_RS10520	COG0439	Biotin carboxylase
B1NLA3E_RS10525	COG3665	Urea carboxylase-associated protein
B1NLA3E_RS10535	COG0531	amino acid
B1NLA3E_RS10550	COG0596	Alpha beta hydrolase
B1NLA3E_RS10560	COG5001	Diguanylate cyclase
B1NLA3E_RS10560	COG4251	negative regulation of phosphorylation
B1NLA3E_RS10560	COG2203	Gaf domain
B1NLA3E_RS10560	COG3706	GGDEF domain
B1NLA3E_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS10600	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_RS10620	COG1725	Transcriptional regulator
B1NLA3E_RS10630	COG4191	Histidine kinase
B1NLA3E_RS10635	COG2204	response regulator
B1NLA3E_RS10650	COG0720	synthase
B1NLA3E_RS10660	COG0302	gtp cyclohydrolase
B1NLA3E_RS10670	COG2861	carbohydrate metabolic process
B1NLA3E_RS10675	COG0561	phosphatase activity
B1NLA3E_RS10710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS10720	COG0789	Transcriptional regulator
B1NLA3E_RS10730	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
B1NLA3E_RS10740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_RS10745	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_RS10750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B1NLA3E_RS10750	COG1587	Uroporphyrinogen-III synthase
B1NLA3E_RS10765	COG0527	aspartate kinase activity
B1NLA3E_RS10770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B1NLA3E_RS10775	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
B1NLA3E_RS10780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
B1NLA3E_RS10790	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_RS10795	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
B1NLA3E_RS10800	COG2188	Transcriptional regulator
B1NLA3E_RS10805	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS10810	COG0561	phosphatase activity
B1NLA3E_RS10820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1NLA3E_RS10835	COG2814	Major facilitator Superfamily
B1NLA3E_RS10855	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS10885	COG1280	lysine exporter protein (LysE YggA)
B1NLA3E_RS10890	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_RS10900	COG0463	Glycosyl transferase, family 2
B1NLA3E_RS10930	COG1802	Transcriptional regulator
B1NLA3E_RS10940	COG0129	dihydroxy-acid dehydratase activity
B1NLA3E_RS10945	COG2755	lipolytic protein G-D-S-L family
B1NLA3E_RS10950	COG1131	(ABC) transporter
B1NLA3E_RS10955	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B1NLA3E_RS10965	COG2814	Major facilitator Superfamily
B1NLA3E_RS10975	COG3123	guanosine phosphorylase activity
B1NLA3E_RS11010	COG0450	alkyl hydroperoxide reductase
B1NLA3E_RS11015	COG3973	AAA domain
B1NLA3E_RS11040	COG0488	(ABC) transporter
B1NLA3E_RS11070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B1NLA3E_RS11075	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS11080	COG5002	protein histidine kinase activity
B1NLA3E_RS11080	COG3850	Histidine kinase
B1NLA3E_RS11085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_RS11120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B1NLA3E_RS11125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS11145	COG0824	Thioesterase
B1NLA3E_RS11155	COG4841	protein insertion into membrane
B1NLA3E_RS11170	COG5002	protein histidine kinase activity
B1NLA3E_RS11175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
B1NLA3E_RS11180	COG3858	chitin binding
B1NLA3E_RS11185	COG1832	CoA-binding protein
B1NLA3E_RS11190	COG0187	DNA topoisomerase II activity
B1NLA3E_RS11195	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B1NLA3E_RS11230	COG2368	4-hydroxyphenylacetate
B1NLA3E_RS11255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_RS11270	COG0716	FMN binding
B1NLA3E_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS11280	COG2030	dehydratase
B1NLA3E_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS11300	COG3243	poly(R)-hydroxyalkanoic acid synthase
B1NLA3E_RS11310	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS11315	COG1136	(ABC) transporter
B1NLA3E_RS11325	COG1131	(ABC) transporter
B1NLA3E_RS11330	COG1725	Transcriptional regulator
B1NLA3E_RS11335	COG1388	LysM domain
B1NLA3E_RS11335	COG0791	NLP P60 protein
B1NLA3E_RS11355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_RS11360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_RS11365	COG0010	Belongs to the arginase family
B1NLA3E_RS11370	COG1228	amidohydrolase
B1NLA3E_RS11375	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B1NLA3E_RS11380	COG2986	histidine ammonia-lyase
B1NLA3E_RS11395	COG2814	Major facilitator Superfamily
B1NLA3E_RS11400	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS11405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_RS11415	COG1183	phosphatidylcholine synthase activity
B1NLA3E_RS11425	COG2197	response regulator
B1NLA3E_RS11430	COG4585	Histidine kinase
B1NLA3E_RS11440	COG3239	Fatty acid desaturase
B1NLA3E_RS11445	COG4948	Mandelate Racemase Muconate Lactonizing
B1NLA3E_RS11455	COG0833	amino acid
B1NLA3E_RS11460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B1NLA3E_RS11460	COG0426	domain, Protein
B1NLA3E_RS11475	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS11480	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_RS11500	COG3104	oligopeptide transport
B1NLA3E_RS11515	COG0778	Nitroreductase
B1NLA3E_RS11525	COG2720	vancomycin resistance protein
B1NLA3E_RS11535	COG1368	sulfuric ester hydrolase activity
B1NLA3E_RS11540	COG1164	Oligoendopeptidase f
B1NLA3E_RS11545	COG4989	oxidoreductase activity
B1NLA3E_RS11565	COG2404	hydrolase activity, acting on ester bonds
B1NLA3E_RS11570	COG1011	Hydrolase
B1NLA3E_RS11580	COG1335	isochorismatase
B1NLA3E_RS11620	COG0697	spore germination
B1NLA3E_RS11670	COG1104	cysteine desulfurase activity
B1NLA3E_RS11680	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_RS11720	COG4221	oxidoreductase activity
B1NLA3E_RS11730	COG1272	protein, Hemolysin III
B1NLA3E_RS11740	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS11750	COG4191	Histidine kinase
B1NLA3E_RS11785	COG1695	Transcriptional regulator
B1NLA3E_RS11805	COG0028	Belongs to the TPP enzyme family
B1NLA3E_RS11815	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_RS11820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B1NLA3E_RS11825	COG1307	EDD domain protein, DegV family
B1NLA3E_RS11840	COG1392	Phosphate transport regulator
B1NLA3E_RS11875	COG0330	HflC and HflK could
B1NLA3E_RS11890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_RS11895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_RS11900	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1NLA3E_RS11905	COG0409	Hydrogenase expression formation protein
B1NLA3E_RS11910	COG0375	protein maturation
B1NLA3E_RS11930	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_RS11935	COG0650	Formate hydrogenlyase subunit 4
B1NLA3E_RS11940	COG0651	ATP synthesis coupled electron transport
B1NLA3E_RS11950	COG2414	aldehyde ferredoxin oxidoreductase
B1NLA3E_RS11955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B1NLA3E_RS11960	COG2207	Transcriptional regulator
B1NLA3E_RS11970	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_RS11975	COG0346	lactoylglutathione lyase activity
B1NLA3E_RS11995	COG4191	Histidine kinase
B1NLA3E_RS12000	COG0069	glutamate synthase activity
B1NLA3E_RS12010	COG2814	Major facilitator Superfamily
B1NLA3E_RS12015	COG4106	trans-aconitate 2-methyltransferase activity
B1NLA3E_RS12030	COG4221	oxidoreductase activity
B1NLA3E_RS12055	COG0653	protein targeting
B1NLA3E_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS12100	COG3339	Conserved Protein
B1NLA3E_RS12140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B1NLA3E_RS12190	COG0622	Phosphoesterase
B1NLA3E_RS12220	COG1074	ATP-dependent DNA helicase activity
B1NLA3E_RS12230	COG0427	acetyl-CoA hydrolase
B1NLA3E_RS12245	COG1876	peptidase activity
B1NLA3E_RS12250	COG0456	acetyltransferase
B1NLA3E_RS12260	COG0058	SHG alpha-glucan phosphorylase activity
B1NLA3E_RS12265	COG0297	glycogen (starch) synthase activity
B1NLA3E_RS12270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_RS12275	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_RS12285	COG0436	Aminotransferase
B1NLA3E_RS12290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_RS12295	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_RS12300	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_RS12305	COG0371	Dehydrogenase
B1NLA3E_RS12310	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS12320	COG3300	MHYT domain
B1NLA3E_RS12320	COG5001	Diguanylate cyclase
B1NLA3E_RS12335	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS12350	COG0667	Aldo Keto reductase
B1NLA3E_RS12360	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS12365	COG1136	(ABC) transporter
B1NLA3E_RS12375	COG2205	protein histidine kinase activity
B1NLA3E_RS12380	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS12395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B1NLA3E_RS12410	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
B1NLA3E_RS12410	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS12430	COG2824	Alkylphosphonate utilization operon protein PhnA
B1NLA3E_RS12435	COG1454	alcohol dehydrogenase
B1NLA3E_RS12450	COG0248	Ppx GppA phosphatase
B1NLA3E_RS12455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
B1NLA3E_RS12460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B1NLA3E_RS12475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_RS12490	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS12495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_RS12500	COG2258	MOSC domain
B1NLA3E_RS12510	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
B1NLA3E_RS12530	COG3594	Acyltransferase
B1NLA3E_RS12540	COG2814	Major facilitator Superfamily
B1NLA3E_RS12550	COG1098	S1 RNA binding domain
B1NLA3E_RS12560	COG2070	2-Nitropropane dioxygenase
B1NLA3E_RS12570	COG0247	lactate metabolic process
B1NLA3E_RS12570	COG2181	nitrate reductase activity
B1NLA3E_RS12585	COG1113	amino acid transport
B1NLA3E_RS12615	COG1247	-acetyltransferase
B1NLA3E_RS12625	COG1605	Chorismate mutase
B1NLA3E_RS12625	COG0077	Prephenate dehydratase
B1NLA3E_RS12635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_RS12650	COG2814	Major facilitator Superfamily
B1NLA3E_RS12655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS12665	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS12670	COG1136	(ABC) transporter
B1NLA3E_RS12680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
B1NLA3E_RS12685	COG1876	peptidase activity
B1NLA3E_RS12690	COG3011	Protein conserved in bacteria
B1NLA3E_RS12695	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_RS12710	COG2323	membrane
B1NLA3E_RS12715	COG1357	PFAM Pentapeptide repeats (8 copies)
B1NLA3E_RS12720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B1NLA3E_RS12740	COG1329	Transcriptional regulator
B1NLA3E_RS12750	COG0463	Glycosyl transferase, family 2
B1NLA3E_RS12760	COG0477	Major facilitator Superfamily
B1NLA3E_RS12775	COG1595	DNA-templated transcription, initiation
B1NLA3E_RS12780	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_RS12790	COG4895	conserved protein (DUF2196)
B1NLA3E_RS12795	COG2848	UPF0210 protein
B1NLA3E_RS12800	COG3830	Belongs to the UPF0237 family
B1NLA3E_RS12810	COG4647	ligase activity
B1NLA3E_RS12815	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
B1NLA3E_RS12820	COG0145	ligase activity
B1NLA3E_RS12830	COG4086	secreted protein
B1NLA3E_RS12835	COG1278	Cold shock
B1NLA3E_RS12850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
B1NLA3E_RS12865	COG3341	Caulimovirus viroplasmin
B1NLA3E_RS12865	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_RS12885	COG1279	arginine transmembrane transporter activity
B1NLA3E_RS12890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_RS12900	COG2027	D-alanyl-D-alanine carboxypeptidase
B1NLA3E_RS12910	COG0708	Exodeoxyribonuclease III
B1NLA3E_RS12915	COG3284	Transcriptional regulator
B1NLA3E_RS12925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1NLA3E_RS12930	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1NLA3E_RS12935	COG0022	dehydrogenase e1 component
B1NLA3E_RS12940	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1NLA3E_RS12945	COG0574	Belongs to the PEP-utilizing enzyme family
B1NLA3E_RS12945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B1NLA3E_RS12950	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B1NLA3E_RS12955	COG0517	IMP dehydrogenase activity
B1NLA3E_RS12975	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1NLA3E_RS13005	COG1657	PFAM Prenyltransferase squalene oxidase
B1NLA3E_RS13030	COG1587	Uroporphyrinogen-III synthase
B1NLA3E_RS13040	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B1NLA3E_RS13045	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_RS13050	COG0531	amino acid
B1NLA3E_RS13055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B1NLA3E_RS13060	COG0157	Belongs to the NadC ModD family
B1NLA3E_RS13065	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B1NLA3E_RS13070	COG1104	cysteine desulfurase activity
B1NLA3E_RS13080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B1NLA3E_RS13085	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B1NLA3E_RS13100	COG5337	Spore coat protein CotH
B1NLA3E_RS13115	COG3773	Cell wall hydrolase
B1NLA3E_RS13125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1NLA3E_RS13135	COG0535	radical SAM domain protein
B1NLA3E_RS13150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_RS13160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B1NLA3E_RS13165	COG2351	hydroxyisourate hydrolase activity
B1NLA3E_RS13175	COG2080	2 iron, 2 sulfur cluster binding
B1NLA3E_RS13180	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B1NLA3E_RS13185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
B1NLA3E_RS13190	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
B1NLA3E_RS13195	COG0402	S-adenosylhomocysteine deaminase activity
B1NLA3E_RS13205	COG0133	tryptophan synthase activity
B1NLA3E_RS13210	COG1418	mRNA catabolic process
B1NLA3E_RS13220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B1NLA3E_RS13230	COG0659	secondary active sulfate transmembrane transporter activity
B1NLA3E_RS13240	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_RS13255	COG0697	spore germination
B1NLA3E_RS13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS13270	COG0765	amino acid transport
B1NLA3E_RS13275	COG1126	abc transporter atp-binding protein
B1NLA3E_RS13285	COG3383	formate dehydrogenase (NAD+) activity
B1NLA3E_RS13290	COG0243	molybdopterin cofactor binding
B1NLA3E_RS13295	COG5002	protein histidine kinase activity
B1NLA3E_RS13305	COG2814	Major facilitator Superfamily
B1NLA3E_RS13310	COG1346	cytolysis
B1NLA3E_RS13315	COG1380	Effector of murein hydrolase LrgA
B1NLA3E_RS13320	COG1999	signal sequence binding
B1NLA3E_RS13325	COG0488	(ABC) transporter
B1NLA3E_RS13340	COG0384	phenazine biosynthesis protein PhzF
B1NLA3E_RS13350	COG1247	-acetyltransferase
B1NLA3E_RS13360	COG0456	acetyltransferase
B1NLA3E_RS13385	COG0725	ABC transporter, periplasmic molybdate-binding protein
B1NLA3E_RS13390	COG4149	molybdate abc transporter
B1NLA3E_RS13395	COG1686	Belongs to the peptidase S11 family
B1NLA3E_RS13410	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B1NLA3E_RS13440	COG2814	Major facilitator Superfamily
B1NLA3E_RS13445	COG1846	Transcriptional regulator
B1NLA3E_RS13450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1NLA3E_RS13450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B1NLA3E_RS13460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS13465	COG0626	cystathionine gamma-synthase activity
B1NLA3E_RS13470	COG0626	cystathionine gamma-synthase activity
B1NLA3E_RS13475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B1NLA3E_RS13475	COG0646	methionine synthase
B1NLA3E_RS13480	COG0646	methionine synthase
B1NLA3E_RS13480	COG1410	methionine synthase
B1NLA3E_RS13485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B1NLA3E_RS13495	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
B1NLA3E_RS13500	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS13530	COG0135	phosphoribosylanthranilate isomerase activity
B1NLA3E_RS13535	COG0134	indole-3-glycerol-phosphate synthase activity
B1NLA3E_RS13540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B1NLA3E_RS13545	COG0512	Glutamine amidotransferase of anthranilate synthase
B1NLA3E_RS13555	COG2814	Major facilitator Superfamily
B1NLA3E_RS13590	COG1278	Cold shock
B1NLA3E_RS13595	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_RS13605	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
B1NLA3E_RS13610	COG3285	dna ligase
B1NLA3E_RS13610	COG1793	dna ligase
B1NLA3E_RS13615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B1NLA3E_RS13620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
B1NLA3E_RS13625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1NLA3E_RS13625	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B1NLA3E_RS13630	COG0307	riboflavin synthase, alpha
B1NLA3E_RS13640	COG4667	esterase of the alpha-beta hydrolase superfamily
B1NLA3E_RS13650	COG1131	(ABC) transporter
B1NLA3E_RS13670	COG0402	S-adenosylhomocysteine deaminase activity
B1NLA3E_RS13680	COG0534	Mate efflux family protein
B1NLA3E_RS13725	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_RS13725	COG0793	Belongs to the peptidase S41A family
B1NLA3E_RS13730	COG1876	peptidase activity
B1NLA3E_RS13745	COG4326	sporulation control protein
B1NLA3E_RS13755	COG4479	Belongs to the UPF0346 family
B1NLA3E_RS13760	COG0534	Mate efflux family protein
B1NLA3E_RS13765	COG4608	Belongs to the ABC transporter superfamily
B1NLA3E_RS13770	COG0444	Belongs to the ABC transporter superfamily
B1NLA3E_RS13775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_RS13780	COG0601	transmembrane transport
B1NLA3E_RS13785	COG0747	negative chemotaxis
B1NLA3E_RS13790	COG0456	acetyltransferase
B1NLA3E_RS13795	COG1846	Transcriptional regulator
B1NLA3E_RS13800	COG2153	protein acetylation
B1NLA3E_RS13815	COG0243	molybdopterin cofactor binding
B1NLA3E_RS13820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_RS13825	COG2223	nitrite transmembrane transporter activity
B1NLA3E_RS13830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B1NLA3E_RS13835	COG2146	nitrite reductase [NAD(P)H] activity
B1NLA3E_RS13840	COG3848	Pyruvate phosphate dikinase
B1NLA3E_RS13840	COG0574	Belongs to the PEP-utilizing enzyme family
B1NLA3E_RS13850	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_RS13860	COG1064	alcohol dehydrogenase
B1NLA3E_RS13865	COG0789	Transcriptional regulator
B1NLA3E_RS13875	COG0110	maltose O-acetyltransferase activity
B1NLA3E_RS13885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_RS13890	COG0477	Major facilitator Superfamily
B1NLA3E_RS13895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B1NLA3E_RS13915	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_RS13965	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_RS13970	COG0789	Transcriptional regulator
B1NLA3E_RS13975	COG0596	Alpha beta hydrolase
B1NLA3E_RS13990	COG0456	acetyltransferase
B1NLA3E_RS14010	COG0488	(ABC) transporter
B1NLA3E_RS14020	COG0702	epimerase
B1NLA3E_RS14035	COG1309	transcriptional regulator
B1NLA3E_RS14055	COG2162	N-hydroxyarylamine O-acetyltransferase activity
B1NLA3E_RS14070	COG2910	NAD(P)H-binding
B1NLA3E_RS14090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_RS14105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B1NLA3E_RS14140	COG1794	racemase activity, acting on amino acids and derivatives
B1NLA3E_RS14155	COG0456	acetyltransferase
B1NLA3E_RS14155	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B1NLA3E_RS14165	COG1268	BioY protein
B1NLA3E_RS14210	COG3344	reverse transcriptase
B1NLA3E_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS14245	COG1595	DNA-templated transcription, initiation
B1NLA3E_RS14270	COG2808	Putative FMN-binding domain
B1NLA3E_RS14295	COG0412	Dienelactone hydrolase
B1NLA3E_RS14300	COG0697	spore germination
B1NLA3E_RS14340	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_RS14345	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS14350	COG1136	(ABC) transporter
B1NLA3E_RS14355	COG5002	protein histidine kinase activity
B1NLA3E_RS14360	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS14370	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_RS14390	COG1121	(ABC) transporter
B1NLA3E_RS14400	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_RS14410	COG5444	nuclease activity
B1NLA3E_RS14435	COG3706	GGDEF domain
B1NLA3E_RS14450	COG5001	Diguanylate cyclase
B1NLA3E_RS14485	COG2207	Transcriptional regulator
B1NLA3E_RS14490	COG0656	L-ascorbic acid biosynthetic process
B1NLA3E_RS14495	COG2814	Major facilitator Superfamily
B1NLA3E_RS14505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B1NLA3E_RS14515	COG0667	Aldo Keto reductase
B1NLA3E_RS14535	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_RS14595	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS14600	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS14605	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS14645	COG1509	lysine 2,3-aminomutase activity
B1NLA3E_RS14650	COG3829	transcription factor binding
B1NLA3E_RS14655	COG0456	acetyltransferase
B1NLA3E_RS14660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_RS14665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B1NLA3E_RS14670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B1NLA3E_RS14675	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
B1NLA3E_RS14680	COG1619	proteins homologs of microcin C7 resistance protein MccF
B1NLA3E_RS14700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1NLA3E_RS14705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
B1NLA3E_RS14715	COG4698	Protein conserved in bacteria
B1NLA3E_RS14725	COG1999	signal sequence binding
B1NLA3E_RS14730	COG1307	EDD domain protein, DegV family
B1NLA3E_RS14735	COG3764	Sortase (surface protein transpeptidase)
B1NLA3E_RS14740	COG0309	Hydrogenase expression formation protein (HypE)
B1NLA3E_RS14745	COG0409	Hydrogenase expression formation protein
B1NLA3E_RS14750	COG0298	carbon dioxide binding
B1NLA3E_RS14755	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
B1NLA3E_RS14760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
B1NLA3E_RS14775	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
B1NLA3E_RS14780	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
B1NLA3E_RS14785	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
B1NLA3E_RS14795	COG0805	protein transport
B1NLA3E_RS14800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_RS14805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B1NLA3E_RS14815	COG1272	protein, Hemolysin III
B1NLA3E_RS14820	COG0204	Acyl-transferase
B1NLA3E_RS14825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B1NLA3E_RS14830	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
B1NLA3E_RS14835	COG2310	stress, protein
B1NLA3E_RS14840	COG3853	Toxic anion resistance protein (TelA)
B1NLA3E_RS14875	COG0861	Integral membrane protein TerC family
B1NLA3E_RS14880	COG2310	stress, protein
B1NLA3E_RS14890	COG0436	Aminotransferase
B1NLA3E_RS14900	COG1819	glycosyl
B1NLA3E_RS14955	COG1413	lyase activity
B1NLA3E_RS14960	COG0488	(ABC) transporter
B1NLA3E_RS14965	COG1418	mRNA catabolic process
B1NLA3E_RS14980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
B1NLA3E_RS14985	COG2226	methyltransferase
B1NLA3E_RS14990	COG1321	iron dependent repressor
B1NLA3E_RS14995	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B1NLA3E_RS15000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B1NLA3E_RS15005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
B1NLA3E_RS15020	COG1278	Cold shock
B1NLA3E_RS15025	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_RS15030	COG0328	RNA-DNA hybrid ribonuclease activity
B1NLA3E_RS15045	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B1NLA3E_RS15055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_RS15065	COG1924	4 iron, 4 sulfur cluster binding
B1NLA3E_RS15075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B1NLA3E_RS15080	COG1755	Isoprenylcysteine carboxyl methyltransferase
B1NLA3E_RS15085	COG3424	synthase
B1NLA3E_RS15100	COG2233	PERMEase
B1NLA3E_RS15105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_RS15115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B1NLA3E_RS15120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B1NLA3E_RS15125	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
B1NLA3E_RS15140	COG1199	ATP-dependent helicase activity
B1NLA3E_RS15145	COG0116	Belongs to the methyltransferase superfamily
B1NLA3E_RS15150	COG3599	regulation of cell shape
B1NLA3E_RS15155	COG4474	Belongs to the UPF0398 family
B1NLA3E_RS15165	COG3359	exonuclease
B1NLA3E_RS15170	COG1111	helicase
B1NLA3E_RS15170	COG1205	dead DEAH box helicase
B1NLA3E_RS15180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS15185	COG1151	hydroxylamine reductase activity
B1NLA3E_RS15195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B1NLA3E_RS15230	COG4499	WXG100 protein secretion system (Wss), protein YukC
B1NLA3E_RS15230	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_RS15240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B1NLA3E_RS15245	COG3935	DnaD domain protein
B1NLA3E_RS15250	COG0017	Asparaginyl-tRNA synthetase
B1NLA3E_RS15265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B1NLA3E_RS15265	COG1199	ATP-dependent helicase activity
B1NLA3E_RS15270	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
B1NLA3E_RS15275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
B1NLA3E_RS15285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B1NLA3E_RS15285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B1NLA3E_RS15290	COG0617	tRNA 3'-terminal CCA addition
B1NLA3E_RS15295	COG0438	transferase activity, transferring glycosyl groups
B1NLA3E_RS15300	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_RS15305	COG1803	Methylglyoxal synthase
B1NLA3E_RS15310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
B1NLA3E_RS15315	COG1694	Mazg nucleotide pyrophosphohydrolase
B1NLA3E_RS15320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS15325	COG2738	Putative neutral zinc metallopeptidase
B1NLA3E_RS15335	COG4347	Protein of unknown function (DUF1405)
B1NLA3E_RS15340	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_RS15340	COG2010	Cytochrome c
B1NLA3E_RS15345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
B1NLA3E_RS15360	COG5582	Belongs to the UPF0302 family
B1NLA3E_RS15365	COG0457	Tetratricopeptide repeat
B1NLA3E_RS15375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B1NLA3E_RS15380	COG0287	Prephenate dehydrogenase
B1NLA3E_RS15385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
B1NLA3E_RS15390	COG4401	Chorismate mutase type I
B1NLA3E_RS15395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
B1NLA3E_RS15400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
B1NLA3E_RS15405	COG0105	UTP biosynthetic process
B1NLA3E_RS15410	COG0142	geranyltranstransferase activity
B1NLA3E_RS15415	COG2226	methyltransferase
B1NLA3E_RS15420	COG0142	geranyltranstransferase activity
B1NLA3E_RS15430	COG0776	regulation of translation
B1NLA3E_RS15435	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
B1NLA3E_RS15460	COG1160	GTP binding
B1NLA3E_RS15480	COG1304	FMN binding
B1NLA3E_RS15485	COG0539	negative regulation of cytoplasmic translation
B1NLA3E_RS15505	COG2959	enzyme of heme biosynthesis
B1NLA3E_RS15510	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_RS15510	COG3773	Cell wall hydrolase
B1NLA3E_RS15515	COG2339	peptidase activity
B1NLA3E_RS15520	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_RS15525	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B1NLA3E_RS15530	COG4862	establishment of competence for transformation
B1NLA3E_RS15535	COG1408	metallophosphoesterase
B1NLA3E_RS15560	COG3546	catalase activity
B1NLA3E_RS15570	COG1705	Flagellar rod assembly protein muramidase FlgJ
B1NLA3E_RS15570	COG1388	LysM domain
B1NLA3E_RS15575	COG1266	CAAX protease self-immunity
B1NLA3E_RS15580	COG0514	ATP-dependent DNA helicase (RecQ)
B1NLA3E_RS15585	COG4955	Helix-turn-helix domain
B1NLA3E_RS15595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B1NLA3E_RS15600	COG0739	heme binding
B1NLA3E_RS15610	COG1595	DNA-templated transcription, initiation
B1NLA3E_RS15615	COG5002	protein histidine kinase activity
B1NLA3E_RS15620	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS15625	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_RS15630	COG1333	cytochrome c biogenesis protein
B1NLA3E_RS15635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS15640	COG1187	pseudouridine synthase activity
B1NLA3E_RS15645	COG0700	Nucleoside recognition
B1NLA3E_RS15650	COG2715	membrane protein required for spore maturation
B1NLA3E_RS15655	COG1686	Belongs to the peptidase S11 family
B1NLA3E_RS15665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B1NLA3E_RS15680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B1NLA3E_RS15685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B1NLA3E_RS15690	COG1547	Domain of unknown function (DUF309)
B1NLA3E_RS15700	COG0531	amino acid
B1NLA3E_RS15710	COG0697	spore germination
B1NLA3E_RS15730	COG1191	sigma factor activity
B1NLA3E_RS15735	COG2172	sigma factor antagonist activity
B1NLA3E_RS15745	COG1686	Belongs to the peptidase S11 family
B1NLA3E_RS15765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
B1NLA3E_RS15770	COG4974	Belongs to the 'phage' integrase family
B1NLA3E_RS15780	COG0735	belongs to the Fur family
B1NLA3E_RS15785	COG1300	Membrane
B1NLA3E_RS15790	COG1379	DNA repair
B1NLA3E_RS15800	COG0667	Aldo Keto reductase
B1NLA3E_RS15815	COG1073	alpha beta
B1NLA3E_RS15830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1NLA3E_RS15835	COG1476	TRANSCRIPTIONal
B1NLA3E_RS15850	COG0300	oxidoreductase activity
B1NLA3E_RS15855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_RS15860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_RS15865	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_RS15875	COG3478	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
B1NLA3E_RS15880	COG0583	DNA-binding transcription factor activity
B1NLA3E_RS15890	COG0778	Nitroreductase
B1NLA3E_RS15900	COG1234	tRNA 3'-trailer cleavage
B1NLA3E_RS15905	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
B1NLA3E_RS15910	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B1NLA3E_RS15915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B1NLA3E_RS15920	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1NLA3E_RS15925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B1NLA3E_RS15930	COG0346	lactoylglutathione lyase activity
B1NLA3E_RS15935	COG1376	ErfK ybiS ycfS ynhG family protein
B1NLA3E_RS15940	COG4129	membrane
B1NLA3E_RS15955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_RS15955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_RS15965	COG0508	dehydrogenase complex catalyzes the overall conversion of
B1NLA3E_RS15970	COG0022	dehydrogenase e1 component
B1NLA3E_RS15975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B1NLA3E_RS15980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B1NLA3E_RS15985	COG3426	butyrate kinase activity
B1NLA3E_RS15995	COG3829	transcription factor binding
B1NLA3E_RS15995	COG3290	protein histidine kinase activity
B1NLA3E_RS16005	COG0584	glycerophosphoryl diester phosphodiesterase
B1NLA3E_RS16010	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS16015	COG0750	zinc metalloprotease
B1NLA3E_RS16020	COG0497	DNA recombination
B1NLA3E_RS16025	COG1438	arginine binding
B1NLA3E_RS16030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B1NLA3E_RS16035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B1NLA3E_RS16045	COG1722	exodeoxyribonuclease VII activity
B1NLA3E_RS16055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
B1NLA3E_RS16065	COG1302	Protein conserved in bacteria
B1NLA3E_RS16070	COG0439	Biotin carboxylase
B1NLA3E_RS16075	COG0511	ligase activity, forming carbon-carbon bonds
B1NLA3E_RS16115	COG3854	ATPases associated with a variety of cellular activities
B1NLA3E_RS16130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_RS16140	COG4555	ABC transporter
B1NLA3E_RS16160	COG1138	Cytochrome C-type biogenesis protein
B1NLA3E_RS16175	COG2010	Cytochrome c
B1NLA3E_RS16185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
B1NLA3E_RS16190	COG0006	proline dipeptidase activity
B1NLA3E_RS16200	COG3872	metal-dependent enzyme
B1NLA3E_RS16210	COG1752	Esterase of the alpha-beta hydrolase superfamily
B1NLA3E_RS16220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B1NLA3E_RS16225	COG0095	Lipoate-protein ligase
B1NLA3E_RS16230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_RS16240	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1NLA3E_RS16245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B1NLA3E_RS16250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
B1NLA3E_RS16255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_RS16290	COG4537	Required for transformation and DNA binding
B1NLA3E_RS16295	COG1459	type II secretion system
B1NLA3E_RS16300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1NLA3E_RS16310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B1NLA3E_RS16390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1NLA3E_RS16415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_RS16440	COG1368	sulfuric ester hydrolase activity
B1NLA3E_RS16445	COG1940	carbohydrate kinase activity
B1NLA3E_RS16455	COG0697	spore germination
B1NLA3E_RS16475	COG0705	Rhomboid family
B1NLA3E_RS16475	COG0457	Tetratricopeptide repeat
B1NLA3E_RS16500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B1NLA3E_RS16505	COG0267	Belongs to the bacterial ribosomal protein bL33 family
B1NLA3E_RS16520	COG0704	Plays a role in the regulation of phosphate uptake
B1NLA3E_RS16535	COG0573	inorganic phosphate transmembrane transporter activity
B1NLA3E_RS16540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B1NLA3E_RS16545	COG0768	penicillin binding
B1NLA3E_RS16550	COG0477	Major facilitator Superfamily
B1NLA3E_RS16560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS16565	COG2839	Protein conserved in bacteria
B1NLA3E_RS16570	COG5521	maltodextrose utilization protein MalA
B1NLA3E_RS16580	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
B1NLA3E_RS16585	COG4709	membrane
B1NLA3E_RS16590	COG5663	Belongs to the 5'(3')-deoxyribonucleotidase family
B1NLA3E_RS16595	COG0735	belongs to the Fur family
B1NLA3E_RS16600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B1NLA3E_RS16605	COG1121	(ABC) transporter
B1NLA3E_RS16615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
B1NLA3E_RS16620	COG0513	Belongs to the DEAD box helicase family
B1NLA3E_RS16630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
B1NLA3E_RS16635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B1NLA3E_RS16640	COG2384	SAM-dependent methyltransferase
B1NLA3E_RS16645	COG2010	Cytochrome c
B1NLA3E_RS16650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B1NLA3E_RS16655	COG0358	DNA primase activity
B1NLA3E_RS16660	COG1671	Belongs to the UPF0178 family
B1NLA3E_RS16670	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
B1NLA3E_RS16675	COG0517	IMP dehydrogenase activity
B1NLA3E_RS16680	COG0423	glycine-tRNA ligase activity
B1NLA3E_RS16685	COG1381	Involved in DNA repair and RecF pathway recombination
B1NLA3E_RS16690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B1NLA3E_RS16695	COG0295	cytidine deaminase activity
B1NLA3E_RS16700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B1NLA3E_RS16705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
B1NLA3E_RS16710	COG1480	7TM receptor with intracellular HD hydrolase
B1NLA3E_RS16715	COG1702	phosphate starvation-inducible protein PhoH
B1NLA3E_RS16730	COG4430	Bacteriocin-protection, YdeI or OmpD-Associated
B1NLA3E_RS16740	COG4864	UPF0365 protein
B1NLA3E_RS16745	COG1030	water channel activity
B1NLA3E_RS16750	COG1610	YqeY-like protein
B1NLA3E_RS16755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
B1NLA3E_RS16760	COG1283	sodium-dependent phosphate transmembrane transporter activity
B1NLA3E_RS16765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
B1NLA3E_RS16775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
B1NLA3E_RS16780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B1NLA3E_RS16785	COG2264	protein methyltransferase activity
B1NLA3E_RS16790	COG0484	heat shock protein binding
B1NLA3E_RS16795	COG0443	Heat shock 70 kDa protein
B1NLA3E_RS16800	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B1NLA3E_RS16805	COG1420	regulation of RNA biosynthetic process
B1NLA3E_RS16810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B1NLA3E_RS16815	COG0481	GTPase activity
B1NLA3E_RS16825	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_RS16835	COG0268	Binds directly to 16S ribosomal RNA
B1NLA3E_RS16840	COG1466	dna polymerase III delta subunit
B1NLA3E_RS16850	COG0658	competence protein
B1NLA3E_RS16850	COG2333	competence protein COMEC
B1NLA3E_RS16855	COG2131	deaminase
B1NLA3E_RS16865	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B1NLA3E_RS16870	COG2226	methyltransferase
B1NLA3E_RS16875	COG0799	negative regulation of ribosome biogenesis
B1NLA3E_RS16880	COG1713	HD superfamily hydrolase involved in NAD metabolism
B1NLA3E_RS16885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B1NLA3E_RS16890	COG1534	Rna-binding protein
B1NLA3E_RS16895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B1NLA3E_RS16900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B1NLA3E_RS16905	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B1NLA3E_RS16915	COG0688	phosphatidylethanolamine metabolic process
B1NLA3E_RS16920	COG1183	phosphatidylcholine synthase activity
B1NLA3E_RS16935	COG0626	cystathionine gamma-synthase activity
B1NLA3E_RS16940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_RS16945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B1NLA3E_RS16950	COG2226	methyltransferase
B1NLA3E_RS16960	COG0768	penicillin binding
B1NLA3E_RS16965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B1NLA3E_RS16970	COG0572	uridine kinase
B1NLA3E_RS16975	COG0826	peptidase U32
B1NLA3E_RS16980	COG0826	peptidase U32
B1NLA3E_RS16985	COG4122	O-methyltransferase activity
B1NLA3E_RS16990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B1NLA3E_RS16995	COG3906	Belongs to the UPF0473 family
B1NLA3E_RS17015	COG0628	permease
B1NLA3E_RS17055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B1NLA3E_RS17070	COG1104	cysteine desulfurase activity
B1NLA3E_RS17075	COG1959	2 iron, 2 sulfur cluster binding
B1NLA3E_RS17080	COG2364	Membrane
B1NLA3E_RS17085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B1NLA3E_RS17090	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
B1NLA3E_RS17095	COG1131	(ABC) transporter
B1NLA3E_RS17100	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B1NLA3E_RS17105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
B1NLA3E_RS17110	COG0124	histidyl-tRNA synthetase
B1NLA3E_RS17120	COG3103	Sh3 type 3 domain protein
B1NLA3E_RS17120	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_RS17120	COG4991	sh3 domain protein
B1NLA3E_RS17125	COG1490	D-aminoacyl-tRNA deacylase activity
B1NLA3E_RS17130	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B1NLA3E_RS17135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B1NLA3E_RS17140	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B1NLA3E_RS17140	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B1NLA3E_RS17145	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1NLA3E_RS17145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B1NLA3E_RS17155	COG2244	polysaccharide biosynthetic process
B1NLA3E_RS17160	COG2323	membrane
B1NLA3E_RS17170	COG1862	Preprotein translocase
B1NLA3E_RS17175	COG0343	queuine tRNA-ribosyltransferase activity
B1NLA3E_RS17180	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
B1NLA3E_RS17210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B1NLA3E_RS17225	COG1827	regulation of RNA biosynthetic process
B1NLA3E_RS17230	COG0077	Prephenate dehydratase
B1NLA3E_RS17235	COG4492	Belongs to the UPF0735 family
B1NLA3E_RS17240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B1NLA3E_RS17245	COG3290	protein histidine kinase activity
B1NLA3E_RS17255	COG2868	ribosomal protein
B1NLA3E_RS17265	COG1530	ribonuclease E activity
B1NLA3E_RS17270	COG1994	Peptidase M50
B1NLA3E_RS17275	COG0739	heme binding
B1NLA3E_RS17280	COG2894	cell division
B1NLA3E_RS17290	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B1NLA3E_RS17295	COG1792	Involved in formation and maintenance of cell shape
B1NLA3E_RS17300	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_RS17305	COG2003	Belongs to the UPF0758 family
B1NLA3E_RS17335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
B1NLA3E_RS17345	COG1459	type II secretion system
B1NLA3E_RS17355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B1NLA3E_RS17385	COG0285	dihydrofolate synthase activity
B1NLA3E_RS17390	COG0525	valine-tRNA ligase activity
B1NLA3E_RS17400	COG1388	LysM domain
B1NLA3E_RS17405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
B1NLA3E_RS17410	COG0113	porphobilinogen synthase activity
B1NLA3E_RS17420	COG0181	hydroxymethylbilane synthase activity
B1NLA3E_RS17425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
B1NLA3E_RS17445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
B1NLA3E_RS17450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
B1NLA3E_RS17455	COG0470	DNA polymerase III
B1NLA3E_RS17455	COG1067	ATP-dependent peptidase activity
B1NLA3E_RS17465	COG0544	peptidyl-prolyl cis-trans isomerase activity
B1NLA3E_RS17470	COG0457	Tetratricopeptide repeat
B1NLA3E_RS17470	COG1477	protein flavinylation
B1NLA3E_RS17475	COG0066	3-isopropylmalate dehydratase activity
B1NLA3E_RS17480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
B1NLA3E_RS17485	COG0473	3-isopropylmalate dehydrogenase activity
B1NLA3E_RS17490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B1NLA3E_RS17495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
B1NLA3E_RS17500	COG0440	acetolactate synthase activity
B1NLA3E_RS17505	COG0028	Belongs to the TPP enzyme family
B1NLA3E_RS17525	COG0622	Phosphoesterase
B1NLA3E_RS17535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
B1NLA3E_RS17540	COG5401	PFAM Sporulation and spore germination
B1NLA3E_RS17550	COG1846	Transcriptional regulator
B1NLA3E_RS17555	COG2197	response regulator
B1NLA3E_RS17560	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_RS17565	COG1053	succinate dehydrogenase
B1NLA3E_RS17570	COG2009	succinate dehydrogenase
B1NLA3E_RS17590	COG0322	excinuclease ABC activity
B1NLA3E_RS17595	COG3118	belongs to the thioredoxin family
B1NLA3E_RS17600	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS17605	COG2086	electron transfer activity
B1NLA3E_RS17610	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS17615	COG1309	transcriptional regulator
B1NLA3E_RS17630	COG0318	PFAM AMP-dependent synthetase and ligase
B1NLA3E_RS17635	COG3766	membrane
B1NLA3E_RS17645	COG1796	DNA polymerase
B1NLA3E_RS17645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_RS17650	COG1286	toxin biosynthetic process
B1NLA3E_RS17655	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
B1NLA3E_RS17660	COG0072	phenylalanine-tRNA ligase activity
B1NLA3E_RS17660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B1NLA3E_RS17665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
B1NLA3E_RS17670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B1NLA3E_RS17680	COG1363	Peptidase, m42
B1NLA3E_RS17690	COG3326	Membrane
B1NLA3E_RS17695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
B1NLA3E_RS17705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B1NLA3E_RS17710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
B1NLA3E_RS17720	COG1484	DNA-dependent DNA replication
B1NLA3E_RS17725	COG3611	Membrane attachment protein
B1NLA3E_RS17730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B1NLA3E_RS17735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B1NLA3E_RS17740	COG0237	dephospho-CoA kinase activity
B1NLA3E_RS17745	COG1971	Probably functions as a manganese efflux pump
B1NLA3E_RS17750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B1NLA3E_RS17755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_RS17755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B1NLA3E_RS17760	COG5002	protein histidine kinase activity
B1NLA3E_RS17765	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS17770	COG0039	L-malate dehydrogenase activity
B1NLA3E_RS17775	COG0538	isocitrate dehydrogenase activity
B1NLA3E_RS17780	COG0372	Belongs to the citrate synthase family
B1NLA3E_RS17785	COG2707	UPF0756 membrane protein
B1NLA3E_RS17790	COG0628	permease
B1NLA3E_RS17795	COG3030	protein affecting phage T7 exclusion by the F plasmid
B1NLA3E_RS17805	COG0205	6-phosphofructokinase activity
B1NLA3E_RS17810	COG0825	malonyl-CoA metabolic process
B1NLA3E_RS17815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
B1NLA3E_RS17820	COG2186	Transcriptional regulator
B1NLA3E_RS17825	COG0281	malic enzyme
B1NLA3E_RS17830	COG0587	DNA-directed DNA polymerase activity
B1NLA3E_RS17845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B1NLA3E_RS17855	COG4109	DRTGG domain
B1NLA3E_RS17865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
B1NLA3E_RS17870	COG0006	proline dipeptidase activity
B1NLA3E_RS17880	COG0589	response to stress
B1NLA3E_RS17885	COG0165	Argininosuccinate lyase
B1NLA3E_RS17890	COG0137	argininosuccinate synthase activity
B1NLA3E_RS17900	COG0521	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_RS17910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B1NLA3E_RS17915	COG0827	DNA restriction-modification system
B1NLA3E_RS17920	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
B1NLA3E_RS17925	COG3874	Sporulation protein YtfJ
B1NLA3E_RS17935	COG1714	RDD family
B1NLA3E_RS17940	COG0616	signal peptide processing
B1NLA3E_RS17945	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B1NLA3E_RS17960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_RS17975	COG1104	cysteine desulfurase activity
B1NLA3E_RS17980	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
B1NLA3E_RS17985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_RS17990	COG1309	transcriptional regulator
B1NLA3E_RS18025	COG2199	diguanylate cyclase activity
B1NLA3E_RS18025	COG2203	Gaf domain
B1NLA3E_RS18030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
B1NLA3E_RS18035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B1NLA3E_RS18045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B1NLA3E_RS18050	COG0454	-acetyltransferase
B1NLA3E_RS18055	COG0517	IMP dehydrogenase activity
B1NLA3E_RS18060	COG0123	including yeast histone deacetylase and acetoin utilization protein
B1NLA3E_RS18070	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B1NLA3E_RS18070	COG1605	Chorismate mutase
B1NLA3E_RS18075	COG3118	belongs to the thioredoxin family
B1NLA3E_RS18080	COG4980	gas vesicle protein
B1NLA3E_RS18085	COG4768	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
B1NLA3E_RS18090	COG2309	aminopeptidase activity
B1NLA3E_RS18095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B1NLA3E_RS18100	COG1674	ftsk spoiiie
B1NLA3E_RS18105	COG4848	Belongs to the UPF0354 family
B1NLA3E_RS18110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS18120	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
B1NLA3E_RS18125	COG1363	Peptidase, m42
B1NLA3E_RS18130	COG5584	Small secreted protein
B1NLA3E_RS18135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B1NLA3E_RS18145	COG0510	thiamine kinase activity
B1NLA3E_RS18150	COG1523	belongs to the glycosyl hydrolase 13 family
B1NLA3E_RS18155	COG1597	lipid kinase activity
B1NLA3E_RS18165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B1NLA3E_RS18175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_RS18180	COG1349	DNA-binding transcription factor activity
B1NLA3E_RS18185	COG1187	pseudouridine synthase activity
B1NLA3E_RS18195	COG2244	polysaccharide biosynthetic process
B1NLA3E_RS18200	COG2081	HI0933 family
B1NLA3E_RS18220	COG1309	transcriptional regulator
B1NLA3E_RS18225	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1NLA3E_RS18225	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_RS18240	COG4221	oxidoreductase activity
B1NLA3E_RS18245	COG1902	pentaerythritol trinitrate reductase activity
B1NLA3E_RS18250	COG0789	Transcriptional regulator
B1NLA3E_RS18255	COG1733	regulation of RNA biosynthetic process
B1NLA3E_RS18260	COG2085	NADP oxidoreductase coenzyme F420-dependent
B1NLA3E_RS18285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_RS18290	COG0495	leucyl-tRNA aminoacylation
B1NLA3E_RS18295	COG2814	Major facilitator Superfamily
B1NLA3E_RS18300	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
B1NLA3E_RS18310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS18325	COG1138	Cytochrome C-type biogenesis protein
B1NLA3E_RS18345	COG1242	4 iron, 4 sulfur cluster binding
B1NLA3E_RS18350	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B1NLA3E_RS18360	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS18365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B1NLA3E_RS18370	COG0367	asparagine synthase
B1NLA3E_RS18375	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
B1NLA3E_RS18390	COG1506	peptidase
B1NLA3E_RS18395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_RS18400	COG1116	anion transmembrane transporter activity
B1NLA3E_RS18405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS18415	COG0494	nUDIX hydrolase
B1NLA3E_RS18430	COG0783	Belongs to the Dps family
B1NLA3E_RS18435	COG1854	S-ribosylhomocysteine lyase activity
B1NLA3E_RS18440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
B1NLA3E_RS18445	COG0288	reversible hydration of carbon dioxide
B1NLA3E_RS18450	COG0803	Belongs to the bacterial solute-binding protein 9 family
B1NLA3E_RS18455	COG4948	Mandelate Racemase Muconate Lactonizing
B1NLA3E_RS18465	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
B1NLA3E_RS18470	COG0596	Alpha beta hydrolase
B1NLA3E_RS18475	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B1NLA3E_RS18480	COG1169	isochorismate synthase
B1NLA3E_RS18485	COG1575	Belongs to the MenA family. Type 1 subfamily
B1NLA3E_RS18495	COG0058	SHG alpha-glucan phosphorylase activity
B1NLA3E_RS18500	COG0297	glycogen (starch) synthase activity
B1NLA3E_RS18505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_RS18510	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
B1NLA3E_RS18650	COG1285	pathogenesis
B1NLA3E_RS18655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B1NLA3E_RS18670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
B1NLA3E_RS18690	COG1012	belongs to the aldehyde dehydrogenase family
B1NLA3E_RS18700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS18705	COG2368	4-hydroxyphenylacetate
B1NLA3E_RS18710	COG2368	4-hydroxyphenylacetate
B1NLA3E_RS18715	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_RS18725	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_RS18745	COG0789	Transcriptional regulator
B1NLA3E_RS18750	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
B1NLA3E_RS18755	COG0671	phosphoesterase, PA-phosphatase related
B1NLA3E_RS18785	COG2814	Major facilitator Superfamily
B1NLA3E_RS18790	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B1NLA3E_RS18805	COG2197	response regulator
B1NLA3E_RS18810	COG1191	sigma factor activity
B1NLA3E_RS18820	COG0455	bacterial-type flagellum organization
B1NLA3E_RS18825	COG1419	protein localization to endoplasmic reticulum
B1NLA3E_RS18830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B1NLA3E_RS18835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
B1NLA3E_RS18840	COG1684	flagellar biosynthetic protein fliR
B1NLA3E_RS18845	COG1987	bacterial-type flagellum assembly
B1NLA3E_RS18850	COG1338	Plays a role in the flagellum-specific transport system
B1NLA3E_RS18870	COG1157	protein secretion by the type III secretion system
B1NLA3E_RS18880	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_RS18885	COG1766	The M ring may be actively involved in energy transduction
B1NLA3E_RS18890	COG1677	Flagellar hook-basal body complex protein FliE
B1NLA3E_RS18895	COG1558	bacterial-type flagellum-dependent cell motility
B1NLA3E_RS18900	COG1815	bacterial-type flagellum-dependent cell motility
B1NLA3E_RS18920	COG1516	flagellar protein fliS
B1NLA3E_RS18935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
B1NLA3E_RS18940	COG1256	bacterial-type flagellum assembly
B1NLA3E_RS18940	COG4786	Flagellar basal body rod
B1NLA3E_RS18960	COG1334	flagellar protein FlaG
B1NLA3E_RS18970	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
B1NLA3E_RS18975	COG4786	Flagellar basal body rod
B1NLA3E_RS18980	COG4786	Flagellar basal body rod
B1NLA3E_RS18990	COG1728	Protein conserved in bacteria
B1NLA3E_RS18995	COG0840	transmembrane signaling receptor activity
B1NLA3E_RS19000	COG0835	chemotaxis
B1NLA3E_RS19005	COG0835	chemotaxis
B1NLA3E_RS19010	COG2198	Histidine kinase
B1NLA3E_RS19010	COG0643	Histidine kinase
B1NLA3E_RS19015	COG2201	protein-glutamate methylesterase activity
B1NLA3E_RS19020	COG1776	CheC inhibitor of MCP methylation
B1NLA3E_RS19020	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_RS19025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
B1NLA3E_RS19030	COG4786	Flagellar basal body rod
B1NLA3E_RS19035	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
B1NLA3E_RS19045	COG2201	protein-glutamate methylesterase activity
B1NLA3E_RS19050	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
B1NLA3E_RS19055	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
B1NLA3E_RS19080	COG1396	sequence-specific DNA binding
B1NLA3E_RS19085	COG0730	response to heat
B1NLA3E_RS19090	COG0753	catalase activity
B1NLA3E_RS19095	COG0385	Bile acid
B1NLA3E_RS19100	COG0783	Belongs to the Dps family
B1NLA3E_RS19105	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_RS19115	COG3773	Cell wall hydrolase
B1NLA3E_RS19120	COG2814	Major facilitator Superfamily
B1NLA3E_RS19130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_RS19140	COG0697	spore germination
B1NLA3E_RS19145	COG0352	thiamine-phosphate diphosphorylase activity
B1NLA3E_RS19150	COG0351	phosphomethylpyrimidine kinase
B1NLA3E_RS19155	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
B1NLA3E_RS19175	COG0205	6-phosphofructokinase activity
B1NLA3E_RS19180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B1NLA3E_RS19185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_RS19190	COG0698	ribose 5-phosphate isomerase
B1NLA3E_RS19200	COG1063	alcohol dehydrogenase
B1NLA3E_RS19205	COG3775	system Galactitol-specific IIC component
B1NLA3E_RS19210	COG3414	Phosphotransferase system galactitol-specific IIB component
B1NLA3E_RS19215	COG3414	Phosphotransferase system galactitol-specific IIB component
B1NLA3E_RS19235	COG0004	ammonium transporteR
B1NLA3E_RS19245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B1NLA3E_RS19260	COG1979	alcohol dehydrogenase
B1NLA3E_RS19265	COG2155	Conserved Protein
B1NLA3E_RS19270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B1NLA3E_RS19275	COG1098	S1 RNA binding domain
B1NLA3E_RS19285	COG0436	Aminotransferase
B1NLA3E_RS19290	COG1522	sequence-specific DNA binding
B1NLA3E_RS19295	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS19300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B1NLA3E_RS19305	COG2032	superoxide dismutase activity
B1NLA3E_RS19315	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B1NLA3E_RS19325	COG5018	Exonuclease
B1NLA3E_RS19330	COG2050	protein possibly involved in aromatic compounds catabolism
B1NLA3E_RS19335	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_RS19340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
B1NLA3E_RS19345	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
B1NLA3E_RS19350	COG3584	3D domain protein
B1NLA3E_RS19360	COG1252	NADH dehydrogenase
B1NLA3E_RS19385	COG0316	Belongs to the HesB IscA family
B1NLA3E_RS19395	COG1252	NADH dehydrogenase
B1NLA3E_RS19400	COG4837	Protein of unknown function (DUF1462)
B1NLA3E_RS19405	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
B1NLA3E_RS19410	COG0083	homoserine kinase activity
B1NLA3E_RS19415	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B1NLA3E_RS19420	COG0460	homoserine dehydrogenase
B1NLA3E_RS19425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_RS19430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B1NLA3E_RS19435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B1NLA3E_RS19440	COG0647	UMP catabolic process
B1NLA3E_RS19445	COG2445	Protein of unknown function DUF86
B1NLA3E_RS19455	COG4470	Protein conserved in bacteria
B1NLA3E_RS19465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B1NLA3E_RS19470	COG0739	heme binding
B1NLA3E_RS19480	COG3377	Domain of unknown function (DUF1805)
B1NLA3E_RS19485	COG0737	Belongs to the 5'-nucleotidase family
B1NLA3E_RS19490	COG0719	Fe-S assembly protein
B1NLA3E_RS19495	COG0822	iron-sulfur transferase activity
B1NLA3E_RS19500	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B1NLA3E_RS19505	COG0719	Fe-S assembly protein
B1NLA3E_RS19510	COG0396	ATPase activity
B1NLA3E_RS19515	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_RS19520	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_RS19525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_RS19530	COG2873	o-acetylhomoserine
B1NLA3E_RS19545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS19550	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
B1NLA3E_RS19555	COG0509	glycine decarboxylation via glycine cleavage system
B1NLA3E_RS19560	COG1393	Belongs to the ArsC family
B1NLA3E_RS19565	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS19570	COG0183	Belongs to the thiolase family
B1NLA3E_RS19575	COG1024	Enoyl-CoA hydratase
B1NLA3E_RS19575	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1NLA3E_RS19580	COG0506	proline dehydrogenase activity
B1NLA3E_RS19590	COG1120	ATPase activity
B1NLA3E_RS19595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1NLA3E_RS19600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B1NLA3E_RS19605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B1NLA3E_RS19625	COG0772	Belongs to the SEDS family
B1NLA3E_RS19635	COG1910	domain protein
B1NLA3E_RS19645	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B1NLA3E_RS19650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_RS19655	COG0673	inositol 2-dehydrogenase activity
B1NLA3E_RS19665	COG2112	serine threonine protein kinase
B1NLA3E_RS19670	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B1NLA3E_RS19685	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
B1NLA3E_RS19695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_RS19700	COG1227	inorganic diphosphatase activity
B1NLA3E_RS19705	COG0004	ammonium transporteR
B1NLA3E_RS19725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_RS19750	COG2706	6-phosphogluconolactonase activity
B1NLA3E_RS19755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B1NLA3E_RS19755	COG0392	lysyltransferase activity
B1NLA3E_RS19760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B1NLA3E_RS19765	COG4990	cell redox homeostasis
B1NLA3E_RS19770	COG4990	cell redox homeostasis
B1NLA3E_RS19790	COG0071	Belongs to the small heat shock protein (HSP20) family
B1NLA3E_RS19805	COG4221	oxidoreductase activity
B1NLA3E_RS19810	COG5002	protein histidine kinase activity
B1NLA3E_RS19815	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS19820	COG1132	(ABC) transporter
B1NLA3E_RS19830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B1NLA3E_RS19835	COG0196	riboflavin kinase activity
B1NLA3E_RS19845	COG3300	MHYT domain
B1NLA3E_RS19845	COG5001	Diguanylate cyclase
B1NLA3E_RS19855	COG0805	protein transport
B1NLA3E_RS19865	COG4149	molybdate abc transporter
B1NLA3E_RS19870	COG0725	ABC transporter, periplasmic molybdate-binding protein
B1NLA3E_RS19880	COG0314	molybdopterin synthase activity
B1NLA3E_RS19885	COG1763	Mo-molybdopterin cofactor biosynthetic process
B1NLA3E_RS19890	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B1NLA3E_RS19895	COG0303	'Molybdopterin
B1NLA3E_RS19900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_RS19905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_RS19915	COG3302	dmso reductase anchor subunit
B1NLA3E_RS19920	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_RS19925	COG0243	molybdopterin cofactor binding
B1NLA3E_RS19930	COG2964	Protein conserved in bacteria
B1NLA3E_RS19935	COG0251	oxidation-reduction process
B1NLA3E_RS19940	COG0626	cystathionine gamma-synthase activity
B1NLA3E_RS19945	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B1NLA3E_RS19950	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B1NLA3E_RS19955	COG0833	amino acid
B1NLA3E_RS19960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B1NLA3E_RS19980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
B1NLA3E_RS19985	COG0557	exoribonuclease II activity
B1NLA3E_RS19990	COG1647	Serine aminopeptidase, S33
B1NLA3E_RS19995	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B1NLA3E_RS20045	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_RS20060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_RS20065	COG1481	regulation of sporulation
B1NLA3E_RS20070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
B1NLA3E_RS20075	COG1660	Displays ATPase and GTPase activities
B1NLA3E_RS20080	COG1051	belongs to the nudix hydrolase family
B1NLA3E_RS20085	COG0492	ferredoxin-NADP+ reductase activity
B1NLA3E_RS20090	COG0457	Tetratricopeptide repeat
B1NLA3E_RS20095	COG0140	phosphoribosyl-ATP diphosphatase activity
B1NLA3E_RS20095	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B1NLA3E_RS20100	COG0107	imidazoleglycerol-phosphate synthase activity
B1NLA3E_RS20105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
B1NLA3E_RS20110	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B1NLA3E_RS20115	COG0131	Imidazoleglycerol-phosphate dehydratase
B1NLA3E_RS20120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B1NLA3E_RS20125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B1NLA3E_RS20130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
B1NLA3E_RS20135	COG0110	maltose O-acetyltransferase activity
B1NLA3E_RS20145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
B1NLA3E_RS20150	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
B1NLA3E_RS20160	COG1950	PFAM Membrane protein of
B1NLA3E_RS20170	COG3595	metallopeptidase activity
B1NLA3E_RS20180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B1NLA3E_RS20205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B1NLA3E_RS20210	COG1309	transcriptional regulator
B1NLA3E_RS20215	COG4549	nuclear export factor GLE1
B1NLA3E_RS20240	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_RS20245	COG2608	mercury ion transmembrane transporter activity
B1NLA3E_RS20270	COG2132	Multicopper oxidase
B1NLA3E_RS20290	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS20295	COG5002	protein histidine kinase activity
B1NLA3E_RS20310	COG5002	protein histidine kinase activity
B1NLA3E_RS20320	COG2217	Heavy metal translocating P-type atpase
B1NLA3E_RS20340	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B1NLA3E_RS20350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
B1NLA3E_RS20365	COG5002	protein histidine kinase activity
B1NLA3E_RS20365	COG3850	Histidine kinase
B1NLA3E_RS20370	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS20375	COG0586	Pfam SNARE associated Golgi protein
B1NLA3E_RS20395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_RS20400	COG3409	Peptidoglycan-binding domain 1 protein
B1NLA3E_RS20400	COG0793	Belongs to the peptidase S41A family
B1NLA3E_RS20405	COG1968	undecaprenyl-diphosphatase activity
B1NLA3E_RS20415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
B1NLA3E_RS20420	COG0791	NLP P60 protein
B1NLA3E_RS20420	COG3883	PFAM NLP P60 protein
B1NLA3E_RS20425	COG2177	Part of the ABC transporter FtsEX involved in
B1NLA3E_RS20430	COG2884	Cell division ATP-binding protein ftsE
B1NLA3E_RS20440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B1NLA3E_RS20445	COG1253	flavin adenine dinucleotide binding
B1NLA3E_RS20450	COG2738	Putative neutral zinc metallopeptidase
B1NLA3E_RS20455	COG0861	Integral membrane protein TerC family
B1NLA3E_RS20505	COG0653	protein targeting
B1NLA3E_RS20510	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B1NLA3E_RS20515	COG2059	Chromate
B1NLA3E_RS20520	COG2059	Chromate
B1NLA3E_RS20535	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B1NLA3E_RS20540	COG4193	domain, Protein
B1NLA3E_RS20545	COG1307	EDD domain protein, DegV family
B1NLA3E_RS20650	COG2197	response regulator
B1NLA3E_RS20655	COG1739	Uncharacterized protein family UPF0029
B1NLA3E_RS20660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B1NLA3E_RS20665	COG1091	dTDP-4-dehydrorhamnose reductase activity
B1NLA3E_RS20680	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B1NLA3E_RS20705	COG4166	transmembrane transport
B1NLA3E_RS20710	COG0860	N-Acetylmuramoyl-L-alanine amidase
B1NLA3E_RS20720	COG1442	glycosyl transferase family 8
B1NLA3E_RS20720	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS20730	COG2244	polysaccharide biosynthetic process
B1NLA3E_RS20755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_RS20760	COG1316	TRANSCRIPTIONal
B1NLA3E_RS20810	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS20820	COG1216	Glycosyl transferase, family 2
B1NLA3E_RS20835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_RS20840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_RS20860	COG0640	Transcriptional regulator
B1NLA3E_RS20865	COG5658	integral membrane protein
B1NLA3E_RS20880	COG3037	sugar-specific permease SgaT UlaA
B1NLA3E_RS20890	COG3711	transcriptional antiterminator
B1NLA3E_RS20895	COG0446	pyridine nucleotide-disulphide oxidoreductase
B1NLA3E_RS20900	COG1937	Protein conserved in bacteria
B1NLA3E_RS20915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_RS20930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_RS20930	COG2199	diguanylate cyclase activity
B1NLA3E_RS20935	COG0346	lactoylglutathione lyase activity
B1NLA3E_RS20940	COG0071	Belongs to the small heat shock protein (HSP20) family
B1NLA3E_RS20945	COG0028	Belongs to the TPP enzyme family
B1NLA3E_RS20975	COG3344	reverse transcriptase
B1NLA3E_RS20990	COG1482	cell wall glycoprotein biosynthetic process
B1NLA3E_RS20995	COG1940	carbohydrate kinase activity
B1NLA3E_RS21015	COG2720	vancomycin resistance protein
B1NLA3E_RS21035	COG2048	Heterodisulfide reductase, subunit B
B1NLA3E_RS21040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_RS21045	COG1053	succinate dehydrogenase
B1NLA3E_RS21055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B1NLA3E_RS21055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B1NLA3E_RS21060	COG0471	metal ion transport
B1NLA3E_RS21065	COG4565	transcriptional regulatory protein
B1NLA3E_RS21070	COG3290	protein histidine kinase activity
B1NLA3E_RS21075	COG3764	Sortase (surface protein transpeptidase)
B1NLA3E_RS21085	COG1278	Cold shock
B1NLA3E_RS21100	COG3853	Toxic anion resistance protein (TelA)
B1NLA3E_RS21105	COG4915	5-bromo-4-chloroindolyl phosphate hydrolysis protein
B1NLA3E_RS21110	COG0833	amino acid
B1NLA3E_RS21130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B1NLA3E_RS21135	COG1053	succinate dehydrogenase
B1NLA3E_RS21140	COG2009	succinate dehydrogenase
B1NLA3E_RS21145	COG1027	Aspartate ammonia-lyase
B1NLA3E_RS21150	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
B1NLA3E_RS21160	COG4191	Histidine kinase
B1NLA3E_RS21165	COG0784	Response regulator, receiver
B1NLA3E_RS21170	COG1609	Transcriptional regulator
B1NLA3E_RS21175	COG1979	alcohol dehydrogenase
B1NLA3E_RS21185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B1NLA3E_RS21190	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
B1NLA3E_RS21195	COG0800	Aldolase
B1NLA3E_RS21200	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS21205	COG2731	YhcH YjgK YiaL family protein
B1NLA3E_RS21210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
B1NLA3E_RS21215	COG0675	Transposase, IS605 OrfB family
B1NLA3E_RS21225	COG2814	Major facilitator Superfamily
B1NLA3E_RS21235	COG2267	carboxylic ester hydrolase activity
B1NLA3E_RS21245	COG0243	molybdopterin cofactor binding
B1NLA3E_RS21255	COG0494	nUDIX hydrolase
B1NLA3E_RS21270	COG0183	Belongs to the thiolase family
B1NLA3E_RS21295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_RS21295	COG0425	Belongs to the sulfur carrier protein TusA family
B1NLA3E_RS21305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B1NLA3E_RS21305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B1NLA3E_RS21310	COG0730	response to heat
B1NLA3E_RS21315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B1NLA3E_RS21320	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
B1NLA3E_RS21375	COG1131	(ABC) transporter
B1NLA3E_RS21380	COG1309	transcriptional regulator
B1NLA3E_RS21385	COG2814	Major facilitator Superfamily
B1NLA3E_RS21400	COG1126	abc transporter atp-binding protein
B1NLA3E_RS21405	COG0765	amino acid transport
B1NLA3E_RS21410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS21415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B1NLA3E_RS21430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B1NLA3E_RS21435	COG1028	Short-chain dehydrogenase reductase Sdr
B1NLA3E_RS21450	COG0398	Pfam SNARE associated Golgi protein
B1NLA3E_RS21455	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
B1NLA3E_RS21455	COG2199	diguanylate cyclase activity
B1NLA3E_RS21475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B1NLA3E_RS21480	COG2011	ABC-type metal ion transport system permease component
B1NLA3E_RS21485	COG1464	Belongs to the NlpA lipoprotein family
B1NLA3E_RS21505	COG2259	Doxx family
B1NLA3E_RS21510	COG1846	Transcriptional regulator
B1NLA3E_RS21520	COG1126	abc transporter atp-binding protein
B1NLA3E_RS21525	COG0765	amino acid transport
B1NLA3E_RS21530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B1NLA3E_RS21575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B1NLA3E_RS21580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B1NLA3E_RS21590	COG1733	regulation of RNA biosynthetic process
B1NLA3E_RS21620	COG0606	chelatase, subunit chli
B1NLA3E_RS21625	COG0252	asparaginase activity
B1NLA3E_RS21700	COG1086	Polysaccharide biosynthesis protein
B1NLA3E_RS21715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B1NLA3E_RS21720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
B1NLA3E_RS21725	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B1NLA3E_RS21735	COG4464	protein tyrosine phosphatase activity
B1NLA3E_RS21740	COG0489	protein tyrosine kinase activity
B1NLA3E_RS21745	COG3944	biosynthesis protein
B1NLA3E_RS21750	COG0791	NLP P60 protein
B1NLA3E_RS21750	COG1388	LysM domain
B1NLA3E_RS21755	COG1785	Belongs to the alkaline phosphatase family
B1NLA3E_RS21760	COG1904	glucuronate isomerase
B1NLA3E_RS21765	COG1609	Transcriptional regulator
B1NLA3E_RS21770	COG0246	Mannitol dehydrogenase
B1NLA3E_RS21775	COG2721	sulfolactate sulfo-lyase activity
B1NLA3E_RS21780	COG0800	Aldolase
B1NLA3E_RS21795	COG3958	Transketolase
B1NLA3E_RS21800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B1NLA3E_RS21810	COG1175	transmembrane transport
B1NLA3E_RS21820	COG2188	Transcriptional regulator
B1NLA3E_RS21825	COG4715	Zinc finger, swim domain protein
B1NLA3E_RS21830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B1NLA3E_RS21860	COG2894	cell division
B1NLA3E_RS21915	COG0366	Alpha amylase catalytic
B1NLA3E_RS21940	COG1484	DNA-dependent DNA replication
B1NLA3E_RS21950	COG0577	efflux transmembrane transporter activity
B1NLA3E_RS21965	COG3842	ATPase activity
B1NLA3E_RS21985	COG0629	single-stranded DNA binding
B1NLA3E_RS22010	COG1077	Cell shape determining protein MreB Mrl
B1NLA3E_RS22015	COG1609	Transcriptional regulator
B1NLA3E_RS22020	COG3829	transcription factor binding
B1NLA3E_RS22035	COG2271	Major facilitator Superfamily
B1NLA3E_RS22040	COG2030	dehydratase
B1NLA3E_RS22050	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B1NLA3E_RS22055	COG0644	oxidoreductase
B1NLA3E_RS22060	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
B1NLA3E_RS22065	COG2086	electron transfer activity
B1NLA3E_RS22070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B1NLA3E_RS22075	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS22085	COG0657	acetylesterase activity
B1NLA3E_RS22095	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
B1NLA3E_RS22105	COG0768	penicillin binding
B1NLA3E_RS22110	COG0739	heme binding
B1NLA3E_RS22120	COG2385	sporulation resulting in formation of a cellular spore
B1NLA3E_RS22135	COG4836	Membrane
B1NLA3E_RS22145	COG1007	ATP synthesis coupled electron transport
B1NLA3E_RS22150	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_RS22155	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B1NLA3E_RS22160	COG0713	ATP synthesis coupled electron transport
B1NLA3E_RS22165	COG0839	Belongs to the complex I subunit 6 family
B1NLA3E_RS22175	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
B1NLA3E_RS22185	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_RS22190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_RS22195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B1NLA3E_RS22225	COG0205	6-phosphofructokinase activity
B1NLA3E_RS22230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B1NLA3E_RS22240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
B1NLA3E_RS22245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
B1NLA3E_RS22255	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1NLA3E_RS22260	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
B1NLA3E_RS22265	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B1NLA3E_RS22270	COG0356	it plays a direct role in the translocation of protons across the membrane
B1NLA3E_RS22285	COG1404	Belongs to the peptidase S8 family
B1NLA3E_RS22295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
B1NLA3E_RS22300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
B1NLA3E_RS22310	COG0698	ribose 5-phosphate isomerase
B1NLA3E_RS22320	COG1971	Probably functions as a manganese efflux pump
B1NLA3E_RS22325	COG0009	L-threonylcarbamoyladenylate synthase
B1NLA3E_RS22340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
B1NLA3E_RS22350	COG0243	molybdopterin cofactor binding
B1NLA3E_RS22355	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_RS22380	COG1435	thymidine kinase activity
B1NLA3E_RS22390	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
B1NLA3E_RS22395	COG1494	fructose-1,6-bisphosphatase
B1NLA3E_RS22405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B1NLA3E_RS22410	COG0191	fructose-bisphosphate aldolase activity
B1NLA3E_RS22415	COG2204	response regulator
B1NLA3E_RS22420	COG4821	SIS domain
B1NLA3E_RS22440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_RS22440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
B1NLA3E_RS22440	COG1703	isobutyryl-CoA mutase activity
B1NLA3E_RS22450	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS22455	COG1960	acyl-CoA dehydrogenase activity
B1NLA3E_RS22460	COG1250	3-hydroxyacyl-CoA dehydrogenase
B1NLA3E_RS22465	COG0183	Belongs to the thiolase family
B1NLA3E_RS22470	COG0247	lactate metabolic process
B1NLA3E_RS22470	COG2181	nitrate reductase activity
B1NLA3E_RS22475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B1NLA3E_RS22495	COG0018	arginyl-trna synthetase
B1NLA3E_RS22500	COG4506	Protein conserved in bacteria
B1NLA3E_RS22505	COG0010	Belongs to the arginase family
B1NLA3E_RS22510	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
B1NLA3E_RS22515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B1NLA3E_RS22530	COG1994	Peptidase M50
B1NLA3E_RS22540	COG3465	dGTPase activity
B1NLA3E_RS22545	COG1078	dGTPase activity
B1NLA3E_RS22570	COG0280	phosphate acetyltransferase
B1NLA3E_RS22575	COG3253	May function as heme-dependent peroxidase
B1NLA3E_RS22585	COG2363	Small membrane protein
B1NLA3E_RS22595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B1NLA3E_RS22605	COG0314	molybdopterin synthase activity
B1NLA3E_RS22610	COG1910	domain protein
B1NLA3E_RS22615	COG0303	'Molybdopterin
B1NLA3E_RS22620	COG0746	molybdenum cofactor guanylyltransferase activity
B1NLA3E_RS22635	COG0437	4 iron, 4 sulfur cluster binding
B1NLA3E_RS22650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B1NLA3E_RS22655	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_RS22660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
B1NLA3E_RS22670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS22680	COG0561	phosphatase activity
B1NLA3E_RS22690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B1NLA3E_RS22695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B1NLA3E_RS22695	COG0723	plastoquinol--plastocyanin reductase activity
B1NLA3E_RS22710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B1NLA3E_RS22720	COG0788	formyltetrahydrofolate deformylase activity
B1NLA3E_RS22735	COG2197	response regulator
B1NLA3E_RS22740	COG1131	(ABC) transporter
B1NLA3E_RS22765	COG2195	Cleaves the N-terminal amino acid of tripeptides
B1NLA3E_RS22770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B1NLA3E_RS22780	COG1187	pseudouridine synthase activity
B1NLA3E_RS22810	COG0579	oxidoreductase
B1NLA3E_RS22820	COG1114	Component of the transport system for branched-chain amino acids
B1NLA3E_RS22850	COG3437	response regulator, receiver
B1NLA3E_RS22850	COG2770	Histidine kinase
B1NLA3E_RS22855	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B1NLA3E_RS22885	COG3290	protein histidine kinase activity
B1NLA3E_RS22900	COG0179	Fumarylacetoacetate (FAA) hydrolase
B1NLA3E_RS22915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
B1NLA3E_RS22925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B1NLA3E_RS22930	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B1NLA3E_RS22935	COG4853	Protein conserved in bacteria
B1NLA3E_RS22940	COG4863	YycH protein
B1NLA3E_RS22945	COG5002	protein histidine kinase activity
B1NLA3E_RS22950	COG0745	RESPONSE REGULATOR receiver
B1NLA3E_RS22955	COG4942	peptidase
B1NLA3E_RS22955	COG1388	LysM domain
B1NLA3E_RS22990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B1NLA3E_RS22995	COG0305	Participates in initiation and elongation during chromosome replication
B1NLA3E_RS23000	COG0359	binds to the 23S rRNA
B1NLA3E_RS23005	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
B1NLA3E_RS23010	COG4241	membrane
B1NLA3E_RS23015	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
B1NLA3E_RS23025	COG0360	Binds together with S18 to 16S ribosomal RNA
B1NLA3E_RS23030	COG0012	GTP binding
B1NLA3E_RS23035	COG4481	Protein conserved in bacteria
B1NLA3E_RS23040	COG0668	transmembrane transport
B1NLA3E_RS23070	COG1475	DNA binding
B1NLA3E_RS23075	COG1192	Involved in chromosome partitioning
B1NLA3E_RS23080	COG1475	DNA binding
B1NLA3E_RS23085	COG0357	Ribosomal RNA small subunit methyltransferase G
B1NLA3E_RS23090	COG0445	tRNA wobble uridine modification
B1NLA3E_RS23095	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
B1NLA3E_RS23100	COG1847	R3H domain protein
B1NLA3E_RS23110	COG0594	ribonuclease P activity
B1NLA3E_RS23145	COG0741	lytic transglycosylase activity
B1NLA3E_RS23145	COG1196	nuclear chromosome segregation
B1NLA3E_RS23145	COG0739	heme binding
B1NLA3E_RS23170	COG0840	transmembrane signaling receptor activity
B1NLA3E_RS23175	COG5002	protein histidine kinase activity
B1NLA3E_RS23185	COG4585	Histidine kinase
B1NLA3E_RS23190	COG5002	protein histidine kinase activity
B1NLA3E_RS23195	COG1388	LysM domain
B1NLA3E_RS23195	COG1705	Flagellar rod assembly protein muramidase FlgJ
B1NLA3E_RS23200	COG0791	NLP P60 protein
B1NLA3E_RS23200	COG1388	LysM domain
B1NLA3E_RS23230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B1NLA3E_RS23265	COG0484	heat shock protein binding
B1NLA3E_RS23270	COG2814	Major facilitator Superfamily
B1NLA3E_RS23275	COG2814	Major facilitator Superfamily
B1NLA3E_RS23285	COG3858	chitin binding
B1NLA3E_RS23310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B1NLA3E_RS23360	COG1596	polysaccharide export
B1NLA3E_RS23360	COG1555	photosystem II stabilization
B1NLA3E_RS23370	COG1388	LysM domain
B1NLA3E_RS23380	COG3190	flagellar
B1NLA3E_RS23385	COG0739	heme binding
B1NLA3E_RS23385	COG0741	lytic transglycosylase activity
B1NLA3E_RS23385	COG1196	nuclear chromosome segregation
B1NLA3E_RS23420	COG0606	chelatase, subunit chli